LOCUS       DACGEU010000001       101124 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.001, whole genome shotgun sequence.
ACCESSION   DACGEU010000001 DACGEU010000000
VERSION     DACGEU010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 101124)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 101124)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..101124
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.001"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            212..604
                     /locus_tag="IXR40_000001"
     CDS             212..604
                     /locus_tag="IXR40_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAQ4359883.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
     gene            632..1972
                     /gene="glnA"
                     /locus_tag="IXR40_000002"
     CDS             632..1972
                     /gene="glnA"
                     /locus_tag="IXR40_000002"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HAQ4359884.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            3165..4775
                     /locus_tag="IXR40_000003"
     CDS             3165..4775
                     /locus_tag="IXR40_000003"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HAQ4359885.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            5067..5936
                     /locus_tag="IXR40_000004"
     CDS             5067..5936
                     /locus_tag="IXR40_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HAQ4359886.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            6101..7372
                     /locus_tag="IXR40_000005"
     CDS             6101..7372
                     /locus_tag="IXR40_000005"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HAQ4359887.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            7369..8664
                     /locus_tag="IXR40_000006"
     CDS             7369..8664
                     /locus_tag="IXR40_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HAQ4359888.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            8763..9026
                     /locus_tag="IXR40_000007"
     CDS             8763..9026
                     /locus_tag="IXR40_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HAQ4359889.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            9471..9920
                     /locus_tag="IXR40_000008"
     CDS             9471..9920
                     /locus_tag="IXR40_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAQ4359890.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            9977..11395
                     /locus_tag="IXR40_000009"
     CDS             9977..11395
                     /locus_tag="IXR40_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4359891.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            11395..12255
                     /locus_tag="IXR40_000010"
     CDS             11395..12255
                     /locus_tag="IXR40_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HAQ4359892.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            12429..13202
                     /locus_tag="IXR40_000011"
     CDS             12429..13202
                     /locus_tag="IXR40_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAQ4359893.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            13349..13714
                     /locus_tag="IXR40_000012"
     CDS             13349..13714
                     /locus_tag="IXR40_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HAQ4359894.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(13862..15070)
                     /locus_tag="IXR40_000013"
     CDS             complement(13862..15070)
                     /locus_tag="IXR40_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAQ4359895.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(15089..15367)
                     /locus_tag="IXR40_000014"
     CDS             complement(15089..15367)
                     /locus_tag="IXR40_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4359896.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            15560..16216
                     /locus_tag="IXR40_000015"
     CDS             15560..16216
                     /locus_tag="IXR40_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HAQ4359897.1"
                     /translation="MDSRVLKEYLDKNDFPIIRKGYHKYLTFEGMEDSHTYILKEGTV
                     KASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESEYAEFYRINRVRFW
                     QNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLYELYDLFGVRTEEG
                     MLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIVILNMDLLEDNIIF
                     "
     gene            complement(16658..17455)
                     /locus_tag="IXR40_000016"
     CDS             complement(16658..17455)
                     /locus_tag="IXR40_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HAQ4359898.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(17452..18636)
                     /locus_tag="IXR40_000017"
     CDS             complement(17452..18636)
                     /locus_tag="IXR40_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HAQ4359899.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(18661..19908)
                     /locus_tag="IXR40_000018"
     CDS             complement(18661..19908)
                     /locus_tag="IXR40_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virion core protein"
                     /protein_id="HAQ4359900.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            20123..21868
                     /gene="dnaX"
                     /locus_tag="IXR40_000019"
     CDS             20123..21868
                     /gene="dnaX"
                     /locus_tag="IXR40_000019"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HAQ4359901.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            21888..22202
                     /locus_tag="IXR40_000020"
     CDS             21888..22202
                     /locus_tag="IXR40_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HAQ4359902.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            22227..22823
                     /gene="recR"
                     /locus_tag="IXR40_000021"
     CDS             22227..22823
                     /gene="recR"
                     /locus_tag="IXR40_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HAQ4359903.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            22887..23531
                     /locus_tag="IXR40_000022"
     CDS             22887..23531
                     /locus_tag="IXR40_000022"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HAQ4359904.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            23546..23875
                     /locus_tag="IXR40_000023"
     CDS             23546..23875
                     /locus_tag="IXR40_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4359905.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            23889..24827
                     /gene="holB"
                     /locus_tag="IXR40_000024"
     CDS             23889..24827
                     /gene="holB"
                     /locus_tag="IXR40_000024"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HAQ4359906.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            24863..25687
                     /locus_tag="IXR40_000025"
     CDS             24863..25687
                     /locus_tag="IXR40_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HAQ4359907.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYDTAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            25680..26027
                     /locus_tag="IXR40_000026"
     CDS             25680..26027
                     /locus_tag="IXR40_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HAQ4359908.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            26096..26968
                     /gene="rsmI"
                     /locus_tag="IXR40_000027"
     CDS             26096..26968
                     /gene="rsmI"
                     /locus_tag="IXR40_000027"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HAQ4359909.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            27077..28198
                     /gene="dinB"
                     /locus_tag="IXR40_000028"
     CDS             27077..28198
                     /gene="dinB"
                     /locus_tag="IXR40_000028"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HAQ4359910.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="IXR40_000029"
     CDS             complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="IXR40_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HAQ4359911.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="IXR40_000030"
     CDS             complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="IXR40_000030"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HAQ4359912.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            31684..32451
                     /locus_tag="IXR40_000031"
     CDS             31684..32451
                     /locus_tag="IXR40_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4359913.1"
                     /translation="MEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGEFVGIMGPSG
                     AGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQEFNLIDTLN
                     AKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQRIAAARALV
                     VQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTASYCDRILFIK
                     DGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            32441..34483
                     /locus_tag="IXR40_000032"
     CDS             32441..34483
                     /locus_tag="IXR40_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4359914.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            34764..34913
                     /locus_tag="IXR40_000033"
     CDS             34764..34913
                     /locus_tag="IXR40_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HAQ4359915.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            34924..36438
                     /gene="dltA"
                     /locus_tag="IXR40_000034"
     CDS             34924..36438
                     /gene="dltA"
                     /locus_tag="IXR40_000034"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HAQ4359916.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            36435..37640
                     /gene="dltB"
                     /locus_tag="IXR40_000035"
     CDS             36435..37640
                     /gene="dltB"
                     /locus_tag="IXR40_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HAQ4359917.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            37685..37918
                     /gene="dltC"
                     /locus_tag="IXR40_000036"
     CDS             37685..37918
                     /gene="dltC"
                     /locus_tag="IXR40_000036"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HAQ4359918.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWCTPNKIIQQATALKG"
     gene            37921..39189
                     /gene="dltD"
                     /locus_tag="IXR40_000037"
     CDS             37921..39189
                     /gene="dltD"
                     /locus_tag="IXR40_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HAQ4359919.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            39330..40412
                     /locus_tag="IXR40_000038"
     CDS             39330..40412
                     /locus_tag="IXR40_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HAQ4359920.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            40412..41215
                     /locus_tag="IXR40_000039"
     CDS             40412..41215
                     /locus_tag="IXR40_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HAQ4359921.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            41285..42025
                     /locus_tag="IXR40_000040"
     CDS             41285..42025
                     /locus_tag="IXR40_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAQ4359922.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            42036..43040
                     /locus_tag="IXR40_000041"
     CDS             42036..43040
                     /locus_tag="IXR40_000041"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HAQ4359923.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(43085..44929)
                     /locus_tag="IXR40_000042"
     CDS             complement(43085..44929)
                     /locus_tag="IXR40_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4359924.1"
                     /translation="MSFFNNIYNKKESFYLRIKWSIIIILSLLFLTGIAYFFYFIFSP
                     ADSNQMKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLEKPLDEANLL
                     IKGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTLTVSSPYQNY
                     AGLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMYKQKRLEYSL
                     ILLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYYWSRMFYYKK
                     WYGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLACIGEAYKNNR
                     FYVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISYNLIDHILNT
                     DKDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLMHTDQTKAKN
                     YVEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLPEELPINDDD
                     LAQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYDTNLFSRGIT
                     EELDDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
     gene            45140..45658
                     /locus_tag="IXR40_000043"
     CDS             45140..45658
                     /locus_tag="IXR40_000043"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HAQ4359925.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            45786..46469
                     /locus_tag="IXR40_000044"
     CDS             45786..46469
                     /locus_tag="IXR40_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HAQ4359926.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            46778..46851
                     /locus_tag="IXR40_000045"
     tRNA            46778..46851
                     /locus_tag="IXR40_000045"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:46812..46814,aa:Arg,seq:tct)
     gene            47010..47369
                     /locus_tag="IXR40_000046"
     CDS             47010..47369
                     /locus_tag="IXR40_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 family protein"
                     /protein_id="HAQ4359927.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            47492..49123
                     /locus_tag="IXR40_000047"
     CDS             47492..49123
                     /locus_tag="IXR40_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HAQ4359928.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(49185..49826)
                     /locus_tag="IXR40_000048"
     CDS             complement(49185..49826)
                     /locus_tag="IXR40_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HAQ4359929.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     gene            50108..50416
                     /gene="rplU"
                     /locus_tag="IXR40_000049"
     CDS             50108..50416
                     /gene="rplU"
                     /locus_tag="IXR40_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HAQ4359930.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            50443..50787
                     /locus_tag="IXR40_000050"
     CDS             50443..50787
                     /locus_tag="IXR40_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HAQ4359931.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            50800..51093
                     /gene="rpmA"
                     /locus_tag="IXR40_000051"
     CDS             50800..51093
                     /gene="rpmA"
                     /locus_tag="IXR40_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HAQ4359932.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
     gene            51500..54334
                     /locus_tag="IXR40_000052"
     CDS             51500..54334
                     /locus_tag="IXR40_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAQ4359933.1"
                     /translation="MAKRIDRIYMYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNS
                     SKDLNQLVREGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDT
                     KDIFAKIIGANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAH
                     HVIDEETELIVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLD
                     EIHRLPPEGQEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRI
                     PINIKLPAFEKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQL
                     KSNIQLVCARGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKIT
                     VAPNDTIMKIQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFY
                     KDHGFSFNADSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKK
                     INLGEERHTNDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLR
                     ANQASGRIGVVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNV
                     QEVDEGSGVILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDL
                     DMLHESLKNFRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNK
                     RQETELEVLALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVI
                     LDQLLMESELEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTT
                     GIGDEEYGFKINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLED
                     QIKVKVPIEEMYYLLRLVHNQLDKKEYTVP"
     gene            54525..55016
                     /locus_tag="IXR40_000053"
     CDS             54525..55016
                     /locus_tag="IXR40_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIB"
                     /protein_id="HAQ4359934.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            55119..56108
                     /gene="manX"
                     /locus_tag="IXR40_000054"
     CDS             55119..56108
                     /gene="manX"
                     /locus_tag="IXR40_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HAQ4359935.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            56141..56944
                     /locus_tag="IXR40_000055"
     CDS             56141..56944
                     /locus_tag="IXR40_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HAQ4359936.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            56965..57879
                     /locus_tag="IXR40_000056"
     CDS             56965..57879
                     /locus_tag="IXR40_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HAQ4359937.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            57962..58336
                     /locus_tag="IXR40_000057"
     CDS             57962..58336
                     /locus_tag="IXR40_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HAQ4359938.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGNNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            58475..58720
                     /locus_tag="IXR40_000058"
     CDS             58475..58720
                     /locus_tag="IXR40_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAQ4359939.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            58892..59956
                     /locus_tag="IXR40_000059"
     CDS             58892..59956
                     /locus_tag="IXR40_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HAQ4359940.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            60202..60627
                     /locus_tag="IXR40_000060"
     CDS             60202..60627
                     /locus_tag="IXR40_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAQ4359941.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            60620..61069
                     /gene="nusB"
                     /locus_tag="IXR40_000061"
     CDS             60620..61069
                     /gene="nusB"
                     /locus_tag="IXR40_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HAQ4359942.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            61166..62020
                     /locus_tag="IXR40_000062"
     CDS             61166..62020
                     /locus_tag="IXR40_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HAQ4359943.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            62021..63358
                     /locus_tag="IXR40_000063"
     CDS             62021..63358
                     /locus_tag="IXR40_000063"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HAQ4359944.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            63363..63587
                     /locus_tag="IXR40_000064"
     CDS             63363..63587
                     /locus_tag="IXR40_000064"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HAQ4359945.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            63589..64479
                     /locus_tag="IXR40_000065"
     CDS             63589..64479
                     /locus_tag="IXR40_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HAQ4359946.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            64488..65306
                     /locus_tag="IXR40_000066"
     CDS             64488..65306
                     /locus_tag="IXR40_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HAQ4359947.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            65413..65862
                     /locus_tag="IXR40_000067"
     CDS             65413..65862
                     /locus_tag="IXR40_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HAQ4359948.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            65880..67562
                     /gene="recN"
                     /locus_tag="IXR40_000068"
     CDS             65880..67562
                     /gene="recN"
                     /locus_tag="IXR40_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HAQ4359949.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(67617..67733)
                     /locus_tag="IXR40_000069"
     CDS             complement(67617..67733)
                     /locus_tag="IXR40_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HAQ4359950.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(67806..68762)
                     /locus_tag="IXR40_000070"
     CDS             complement(67806..68762)
                     /locus_tag="IXR40_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HAQ4359951.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            68933..69301
                     /locus_tag="IXR40_000071"
     CDS             68933..69301
                     /locus_tag="IXR40_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HAQ4359952.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            69471..69902
                     /gene="mraZ"
                     /locus_tag="IXR40_000072"
     CDS             69471..69902
                     /gene="mraZ"
                     /locus_tag="IXR40_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HAQ4359953.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            69923..70882
                     /gene="rsmH"
                     /locus_tag="IXR40_000073"
     CDS             69923..70882
                     /gene="rsmH"
                     /locus_tag="IXR40_000073"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HAQ4359954.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            70887..71288
                     /gene="ftsL"
                     /locus_tag="IXR40_000074"
     CDS             70887..71288
                     /gene="ftsL"
                     /locus_tag="IXR40_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HAQ4359955.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            71289..73481
                     /locus_tag="IXR40_000075"
     CDS             71289..73481
                     /locus_tag="IXR40_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HAQ4359956.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAKNGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            73507..74469
                     /locus_tag="IXR40_000076"
     CDS             73507..74469
                     /locus_tag="IXR40_000076"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HAQ4359957.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            74483..75844
                     /locus_tag="IXR40_000077"
     CDS             74483..75844
                     /locus_tag="IXR40_000077"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HAQ4359958.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            75870..76958
                     /gene="murG"
                     /locus_tag="IXR40_000078"
     CDS             75870..76958
                     /gene="murG"
                     /locus_tag="IXR40_000078"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HAQ4359959.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            76973..78193
                     /locus_tag="IXR40_000079"
     CDS             76973..78193
                     /locus_tag="IXR40_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsQ-type POTRA domain-containing protein"
                     /protein_id="HAQ4359960.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            78349..79674
                     /gene="ftsA"
                     /locus_tag="IXR40_000080"
     CDS             78349..79674
                     /gene="ftsA"
                     /locus_tag="IXR40_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HAQ4359961.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            79697..80938
                     /gene="ftsZ"
                     /locus_tag="IXR40_000081"
     CDS             79697..80938
                     /gene="ftsZ"
                     /locus_tag="IXR40_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HAQ4359962.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            80955..81632
                     /locus_tag="IXR40_000082"
     CDS             80955..81632
                     /locus_tag="IXR40_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HAQ4359963.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            81646..82245
                     /locus_tag="IXR40_000083"
     CDS             81646..82245
                     /locus_tag="IXR40_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HAQ4359964.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            82260..82547
                     /locus_tag="IXR40_000084"
     CDS             82260..82547
                     /locus_tag="IXR40_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HAQ4359965.1"
                     /translation="MYTIALLLHLLQRAAYFYSIILMVYALLSWFPGGYQSGLGRLLA
                     KICEPYISLFDRLPLRIGPLDFTILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            82596..83378
                     /locus_tag="IXR40_000085"
     CDS             82596..83378
                     /locus_tag="IXR40_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HAQ4359966.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            83399..84106
                     /locus_tag="IXR40_000086"
     CDS             83399..84106
                     /locus_tag="IXR40_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HAQ4359967.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            84368..87166
                     /gene="ileS"
                     /locus_tag="IXR40_000087"
     CDS             84368..87166
                     /gene="ileS"
                     /locus_tag="IXR40_000087"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HAQ4359968.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKGYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(87215..88741)
                     /locus_tag="IXR40_000088"
     CDS             complement(87215..88741)
                     /locus_tag="IXR40_000088"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HAQ4359969.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(88756..89403)
                     /locus_tag="IXR40_000089"
     CDS             complement(88756..89403)
                     /locus_tag="IXR40_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HAQ4359970.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(89587..89916)
                     /locus_tag="IXR40_000090"
     CDS             complement(89587..89916)
                     /locus_tag="IXR40_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HAQ4359971.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            90093..90821
                     /gene="sfsA"
                     /locus_tag="IXR40_000091"
     CDS             90093..90821
                     /gene="sfsA"
                     /locus_tag="IXR40_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HAQ4359972.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            90837..91850
                     /locus_tag="IXR40_000092"
     CDS             90837..91850
                     /locus_tag="IXR40_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAQ4359973.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKDELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            91850..93127
                     /locus_tag="IXR40_000093"
     CDS             91850..93127
                     /locus_tag="IXR40_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HAQ4359974.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            93190..95892
                     /locus_tag="IXR40_000094"
     CDS             93190..95892
                     /locus_tag="IXR40_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAQ4359975.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            96044..96361
                     /locus_tag="IXR40_000095"
     CDS             96044..96361
                     /locus_tag="IXR40_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAQ4359976.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            96391..96711
                     /locus_tag="IXR40_000096"
     CDS             96391..96711
                     /locus_tag="IXR40_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAQ4359977.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            96819..98279
                     /locus_tag="IXR40_000097"
     CDS             96819..98279
                     /locus_tag="IXR40_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4359978.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGILPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGSNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            98347..98568
                     /locus_tag="IXR40_000098"
     CDS             98347..98568
                     /locus_tag="IXR40_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4359979.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            98599..98781
                     /locus_tag="IXR40_000099"
     CDS             98599..98781
                     /locus_tag="IXR40_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HAQ4359980.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            98781..99194
                     /locus_tag="IXR40_000100"
     CDS             98781..99194
                     /locus_tag="IXR40_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HAQ4359981.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            99317..100498
                     /locus_tag="IXR40_000101"
     CDS             99317..100498
                     /locus_tag="IXR40_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4359982.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            100887..100960
                     /locus_tag="IXR40_000102"
     tRNA            100887..100960
                     /locus_tag="IXR40_000102"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:100921..100923,aa:Arg,seq:cct)
     gene            complement(101029..>101124)
                     /locus_tag="IXR40_000103"
     CDS             complement(101029..>101124)
                     /locus_tag="IXR40_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HAQ4359983.1"
                     /translation="MSTYLHIVRELEDQDKEKINAVFDSLYKNDN"
BASE COUNT        33039 a        17312 c        21449 g        29324 t
ORIGIN      
        1 aataaaaaca ctaataaagg atagtacagt ataataaaaa ataaaaggta tctggtacga
       61 aaatcaacta gatacctttt ttgtgttctt atttttttgt tattttataa aaaatagaga
      121 tctcatgtta gaaaacctaa catatgcagt tgacaatatt ttttttaatt ggtacacttt
      181 agccaactta taaaacgaaa ggggacgtct gatgggagaa aaggaattgc gccgatctat
      241 gtccgtattt ccaattggta cagttatgaa gctgactgat ttgtctgctc ggcaaattcg
      301 ctattatgaa gaacaagatt tagttcatcc ggaacgaagc gaaggaaacc gacgtatgta
      361 ttcgctgaat gatattgata tgttgcttga gattaaagac tatctttcag agggattgaa
      421 tatggctggg atcaaacgtg tatacgaaat ggcacaggcg aaaaaacaag aagcaaaaaa
      481 caagaagccg ttgacagatc atgacgttcg acaaattttt cgtgatgaga ttttggcgca
      541 aggtgggtta agcaaaacag gtcattatca gtcgcaagga ttgcaaagac aattctttga
      601 ctgaataaat taaaaaagga agagggatac catggtaaag aaacagataa caggtgaaga
      661 aatcaaacga atcattgagg aagaaaacgt acgattttta cgattgatgt tcacagacat
      721 cttaggtacg atcaaaaatg tagaagttcc agtgagccag atcgacaaag tattagaaaa
      781 taaaatgatg tttgacggtt cttcgattga aggatttgtt cgaattgaag aaagcgatat
      841 gtatttgtat ccagatctct ccacttggat gatcttcccg tgggaaagtg ctcatggaaa
      901 agttgctcgt ttaatttgtg atatctataa tccggatggg acaccatttg ccggcgatcc
      961 tcgcgggaat ttgaaacgag cattgaaaga tatgcgcgac cttggtttta cctctttcaa
     1021 tttaggacct gaaccagaat tcttcttatt taaattagac gaagacggtg ggatcacaac
     1081 gaccttgaat gataaaggtg gttattttga ttttgcacca acagatttag gtgaaaattg
     1141 ccgccgtgac atcgtgttgg aattagaaag tctaggcttt gaagtggaag cttcacatca
     1201 tgaagtagcg ccaggacagc atgaaattga ctttaaatat gcagatgtgg tagatgcttg
     1261 tgataatatc caaaccttca agctcgttgt caaaacgatt gcacgcaagc atggacttca
     1321 cgcgactttc atgccgaaac cgttatttgg gatcaatggt tctggtatgc attgcaatat
     1381 gtctttgttc aatgatgaag gaaatgtttt ctatgataaa gacggtgaat tggaactaag
     1441 tgaaacagct tatcatttct taggtggttt gctgaaacat gctcgtgcct acacagccgt
     1501 ttgcaatcca acagtcaatt cttataaacg tctcgttcca ggttatgaag cgcctgttta
     1561 tgtcgcatgg agtggccgta atcgttcgcc attagtacgt gtaccagaat ctcgcggttt
     1621 atccacacgt ttggaattgc ggtcagttga tccatctgca aacccatact tggcaatggc
     1681 agtattgttg caagcaggac tagacggtat ccgtaatcag atcacaccgc cagcagctgt
     1741 tgaccgtaac atttatgtaa tggatgagga agaaagagaa gctgcacata tccaggactt
     1801 accttcaact atccataatg ctatcaaaga attgcgtaag gataatgtaa tgattgacgc
     1861 attaggacaa catatcttct caaattttgt tgaagcaaaa cgtctcgaat gggcggcatt
     1921 cagacaaact gtttccgagt gggaaagaga acaatatcta gaactttatt aaaacaggaa
     1981 taccgtgaat tagaggctgt gaaatcagcg ttttgacctg agtattagag aaactaacgg
     2041 aaaaatagtt cctcatattt tgccgttttt tgagctaata ccgagggtca gctgattgaa
     2101 caccgtttag tggagaggtt gtgaaaaagc tgccctgcaa caagtaataa gaatagccaa
     2161 gcaaaaacag cttttcttgt ttttgaattg gctgaactta ttaccgcaga tgcaagcttt
     2221 tgaacaccgt ttaccaagag gttttgaaaa agacgtttag tttcgagtat taagaaaaat
     2281 tttgtgaaaa tggctttcta catttttgca taaatttggc ttaataccga gaaactggct
     2341 tttgaatacc gtttatccag aggttgtgag cctaccattt aactccgaat cacaagaaat
     2401 aatttcaaaa acagcttctc atgtttgatg gatattgtga cttgtgaccg aggagttggc
     2461 aggagaacac cgtttattta gaaataagga ggcacgactt ttgtcgcatc tccttatttt
     2521 ttacttatgt gattcgttac cttcaatgaa tccctacaag gcacttttgt tgaaaaaaag
     2581 gtcatctttg aaaaaattag tggaattgtt ttgtttttga tattatttaa tagaaaagat
     2641 atgccaaaaa tccgagaact gtggactacg ttttttacgt aaaggaggta aataagggtg
     2701 aaagaaaaag attgtttcta cgataagcta tataaactgt tgctgcaagt aggaaaaagt
     2761 agttctttgt taggtgggat attatctatc ataatgtttg ttttattttt ttatctatta
     2821 tttcacttaa aatttttcag taacgatttt ctgatttgct taggtttaac gttagctatg
     2881 tttatatcaa gcttattatg tgggttaaat tttttttgca ctcataaagg acttaagaaa
     2941 taatttctca aaggatatcg aaaaagaaaa aattgtaagc ggatagtatt catttgagta
     3001 cttgactttc ccttagtcag cttgtattat acaccttggg caccctttta gagggtcaga
     3061 agtttacaga aatttcggct ccctattctt attgaagaat agggagcttt gtttattgtc
     3121 tgagactttt cctgcacata aattaaaaag gagtttttga acttatgaca aaatatattt
     3181 ttgtgaccgg cggtgtcgtt tcatcaatcg gaaaagggat tgttgcagct tctttaggac
     3241 gcttattgaa aaaccgcggc ttaaaagtaa ctatccaaaa atttgatcca tacatcaacg
     3301 tggatccggg gacgatgagc ccatatcagc acggagaagt attcgtaaca gatgatggtg
     3361 ctgaaacaga tttggatctg ggccactacg aacgttttat tgacatcaat ttgaacaaat
     3421 actccaacgt gacgacagga aaaatctatt ctgaagtttt gcgtaaagaa cgtaagggcg
     3481 aatacttggg agcaactgtt caagttattc ctcatattac aaatgagatc aaagaaaaaa
     3541 tcatgcgagc agctaaaatg actgattcag atgtgatcat tacagaagta gggggaacag
     3601 taggggatat agaatctttg ccattccttg aagcacttcg tcaaatgaaa gcagatgtcg
     3661 gtacagataa tgttatgtat atccatacaa cattgattcc ttacttgaaa gctgctggag
     3721 aaatgaaaac taaaccaacg cagcacagtg taaaagagct acgtggttta ggtatccaac
     3781 cgaatatttt ggtggtacgt acagagcaac ctgtttctca aagcgtgaaa aacaaattgg
     3841 cacaattttg tgatgtcgaa ccagaagcag ttatcgagtc gccagatgta gatacacttt
     3901 actccatccc attagtttta caagcacaag gaatggatca aattgtttgc gaccatttaa
     3961 aactagatac accagaagca gacatgacag aatggaaaga attagaagaa cgtgtcttga
     4021 acttgaagaa aaaagtacgg attgcgcttg tcggtaaata tgtcgagtta ccagatgcat
     4081 atatctcagt agttgaagca ttgaaacatt ctggtttcgc ctataattca gacatcgaga
     4141 tcgattggat caaagcacaa gaattaacga gagaaaatgt agaagaacgt ttgaaagacg
     4201 cagatggaat cttggttcct ggtggatttg gtgatcgcgg agtagaaggg aaaatcgaag
     4261 cgattcgtta tgctcgcgaa aatgacgttc cgtttttagg tatttgtctt ggtatgcaga
     4321 tggcttgtgt cgaatttgca cgtaacgtcg ttggattaga agatgcgtca tcagctgaaa
     4381 cgaatccaga tacagcaaac aatattattg atttaatggc tgatcaggaa aacatcgaga
     4441 atttgggtgg aactttacgc cttggattat acccatgtaa aatcaaaaaa ggaacgaaga
     4501 cggctgaagc atatgatgga gccgatgttg tgcaagaacg tcaccgtcac cgctatgagt
     4561 tcaataacaa atatcgtcaa ttgtttgaag aacaagggct agtcttttca ggtgtctcac
     4621 cagataaccg tttagtagaa atcgtagagc tgccagagaa aaaattcttt gtgggatgcc
     4681 aattccaccc agaattgatt tctcgtccaa atcgcccgca aaaattaatc aaagcatttg
     4741 tcggagcatc attagcagat cacgaaacaa aataattttt gaacttgata gaaagagaaa
     4801 agtagcaaga gaaggggata agcaattttc ttgtcacttt tctctttttc tgatttgtta
     4861 ttatttgtag gaaaaaagat agaaagcaaa agactttttt cgattaaagc gctattggat
     4921 attttatttt ttgcaaaaaa cttcttgaaa attttcattt tcattgattt tagtagaaaa
     4981 ctaccgaaat gtttggtaaa atagggtcgt tggttaagaa ttgtcttaac aaatttagtt
     5041 ttacaaaact taggaggaat tttattatgc cagtagtatc aggagctgaa tttttaaaag
     5101 ctgctcgtaa aggcggttac gctgtcggcg gattcaacac aaacaacttg gaatggactc
     5161 aagcaatcct tgaagcggct gaagcaaaac aagcaccagt acttatccaa acatcaatgg
     5221 gtgcagctaa atacatgggt ggttacaaaa tctgtaaaga tttaatcact gatttagttg
     5281 aagcaatgaa catcactgtt ccagttgcta tccacttaga ccatggtgat tacgaagctg
     5341 ctttggaatg tatcgaatta ggctatactt cagtaatgtt cgatggttca catctaccat
     5401 ttgaagaaaa cttgaaatta gctaaagacg ttgttgaaaa agcacatgca aaaggtatct
     5461 cagttgaatg tgaagttggt tcaatcggcg gagaagaaga cggaatcatc ggtaacggcg
     5521 aattagctga tattgaagaa tgcaaacaaa tggttgctac aggtatcgac tacttagctt
     5581 gcggtatcgg taacatccat ggtcaatatc cagaaaactg gaaaggatta gcttttgacc
     5641 acttacaagc aattgctgat gctgtaggtc cagacatgcc tttagtatta catggcggat
     5701 caggtattcc tcaagatcaa atcgaaaaag ctatctcaat gggtatctca aaagtaaatg
     5761 ttaacactga attccaatta tcatttgctg cagctactcg taaatatatc gaagctggta
     5821 aagataaaga aggtaaagga ttcgaccctc gtaaattatt agctccaggt aaagcagcaa
     5881 tcgttgaaga tgctaaatct catatcgact ggttcggttc agctaacaaa gcgtaagcat
     5941 ccacataaca gatacgatat ataggaatgg agaacgactt ttgaagtcgc tctccattct
     6001 tttttactta aaacggcaga ccatgctcgt ttcttttttt tatctatgat aaaatacaag
     6061 catatccatg aaaaaagatt aataaacaag gtggaaacag atgaaaaaaa tcgtaatcaa
     6121 aggaaaccga cctttagctg gtgaagtaac gatcagcggt gcaaaaaata gtgcagtcgc
     6181 attgattcca gctgcaatct tagctgattc cccagtgatc ttggaaggtg tgccggacat
     6241 acaagatgtt cattcattaa ttgaaatttt agagatcatg ggcgcaactg tccatttttc
     6301 caacaacata ctagaaatcg atcctcgaga agtcgtatcg attccgatgc cgcacggaaa
     6361 aatcaatagt ttgcgtgctt cttattattt tatgggaaca ctgcttggta aatttggcga
     6421 agcggtagta ggcctgccag gtggctgtta tttaggccct agaccgattg acctacacgt
     6481 caaaggattt gaagctctag gtgctgaagt gacaaatgaa catggtgcca tgtatttacg
     6541 gacagaaaat aaaggattgc gtggcaatcg gattttcatg gacgtggttt cagtcggagc
     6601 aacgatcaat gtgatgttag ctgctgtaaa agcaaaagga cagacagtaa ttgaaaacgc
     6661 tgcacgagaa ccggaaatca tagatgtggc aactttactg aataatatgg gggcaaaagt
     6721 tcgaggagcg ggtacagatg tgatccgtat cgaaggagtc gaaacattac atggctgtcg
     6781 gcatttcatg attcctgacc gcatcgaagc aggaacctat ctagcattag cagctgcagt
     6841 aggaaatggt atcaaagtga aaaatgtgat ctttgaacat ttggaaagct ttatagcaaa
     6901 attgcaggaa attggtgtcc atatgaaaat cagcgaagat gaaatcgaag tttacccctc
     6961 gaaagaatta aaacccgcaa acatcatgac ctatccttat ccaggatttg ccacagatct
     7021 gcagcagcca cttactgcgt tactattgat gactacaggc acttcagaaa tcatcgatac
     7081 gatctatgcg aaacgtgtga accatgtgcc ggaactagca cgaatgggcg ctgatattac
     7141 cgtggaagga aatatgatca tcgtgaatgg tccaaataaa cttcacggca cagaagtcgt
     7201 ggcttctgat cttcgggcag gtgcttgttt agtgattgct ggactattgg cagaagggac
     7261 aacgacgatt tacaatgtag attatatctt acgcggttat gatcatatta tcgagaaact
     7321 aacagcctta ggggcatcaa ttgaaatgat agaggaagtg ggagctgaat gagcgattat
     7381 ttgacaatgg cagaactaga gaacaaaacg ttaaaagaag tttatagtta tgccaaagaa
     7441 tttaaaattc cttattacag taagatgaat aaaaaggaat tatctctagc tgtgattcgt
     7501 gcacaagcag agaaacaagg attttattat atggaaggaa tattggatat cgttggtcaa
     7561 gatggttacg gttttttacg gccaatcaat tatggaccaa gtgcagaaga tatctatatt
     7621 tctgcctcac aaatcagacg attcagtttg agaaatgggg acaaagtggc aggaaaagcc
     7681 cgtccaccta aagaatcgga acgttattat ggtttgatgc acgtggaaag cgttaatgga
     7741 aaagatccgg aagaagcaaa agaacgtccg cattttccag ccttaacacc tctttatccg
     7801 caaagacagc ttcaactgga aacaacaccg caaagactat ctacccgaat gatcgatatc
     7861 ttttctccaa tcggttttgg tcagcgtgga ttgatcgtcg caccgccaaa agcagggaaa
     7921 acttctgtat taaaagaaat cgcaaatggt atcaccgaaa actatccgga agtagaatta
     7981 atcgttctac tgattgatga acgaccggaa gaagtaacgg atctagaacg aagcgtgaaa
     8041 ggcgacgtgg tatcttctac atttgatctg cagccgcaaa accatactcg agtttctgaa
     8101 ttagtattgg aacgcgcaat gcgtttagtc gaagataaac gagatgtcgt tatcttgatg
     8161 gatagtatta ctagacttgc tcgggcctat aacttagtcg ttccaccaag cggacgtaca
     8221 ttgagtggcg ggattgaccc agccgcattg tataaaccta agaaattttt cggggcagca
     8281 agaaacatcg aagaaggtgg cagtttgacg attttagcga ccgctttagt cgatacagga
     8341 agccgtatgg atgacgtgat ctatgaagaa ttcaaaggaa ctggaaatct agaattacaa
     8401 ctttcacgtg aattatctga acgtcggatc ttcccagcca tcgatatcaa aaaatcaggt
     8461 acccgaaaag aagaattatt gatgccaagt gaagaattag aagaaatttg gaaacttcga
     8521 aaaaatatga ctggagattc attagaatat acggaacaac tgatccgctt tttgcgtaaa
     8581 acaaaaaaca atcagcaatt tttcaaagaa tttcaagatg tctcctttgg taaaaaaaat
     8641 ccgaccagaa atctgaaaag ataattgcaa ccttgactga aacatgttaa gatgttaatg
     8701 ttgtaaatcg acaaatcaac tctggttcag caaatggagc agggcaaagg agcgaaaaaa
     8761 tcatgaaaga aaacatccat ccagattacc acccagtagt attcatggat tcaacaactg
     8821 gtttcaaatt cttgtcaggt tcaacaaaaa cttcacaaga aacagttgaa tgggaagacg
     8881 gtaatacata cccagtcatc cgtgtcgaag taacttctga ctcacatcca ttctacactg
     8941 gacgtcaaaa attcacacaa gcagacggac gtgtggaccg tttcaacaaa aaatacggtc
     9001 tcaaagacgc aaacgctgcg gaataataaa aacgctgata actcaacgtt tagcagacta
     9061 tctgataggg atagtctgtt tttttatgtt ttttgccaat ttaaaacttc gtttgatgct
     9121 gaaaaagtcg taggatcata atgcacaaaa caatgaaaaa ctagtatata gttttaatta
     9181 tccacttgat aaaaacacct tatattaacg aaatgaagag gggttatttc gaagtaaaaa
     9241 accatttacc taaaattaga agctaagctt tcctttcaag gaaggctttt tgttttgtta
     9301 tagacttgcg attgtttgtg agctagatcg ttcattttaa tgacttatac acgcggatga
     9361 tgggtctttt tcctctgttc attcataata ttgaacggta cagctagcga tgctatactg
     9421 acctcagttc caagaaaacg ttaacatttt ttgtggggga gaggtttttt atgaggtttg
     9481 atcaattgat cgcagaagaa ctgattgttt tcgatccatc gatagattca aaaggatcat
     9541 tatttgagcg aataggggat gtgttgaaaa aaacaaataa ggtaagaaat gttcaaaaag
     9601 tcgttaaggc actattcaaa cgagaggagg agatctccac aggaatagaa gatggatttg
     9661 ggattcccca tgcaaaaagc aaatatgtga caaaaccagc actgtgtttt tttcatacag
     9721 ccaaattaac ggactatagc gggatagatg aaatgccaat tgaatatatt tttgccatcg
     9781 tagttcctga aaaatcagca gatatgcatc tagagattct cagcacactc tccagacgat
     9841 tgatgaatgc agattttaga aagggaataa aagaagccac tacgccagca gatatcatca
     9901 gacagattag tcaagaatga aaatagtaga gtctttgtcc gagtatcgat agtgaagaaa
     9961 aaggaggaaa ataatcatga aaatcgttgg tgtaactgct tgcccgactg gaattgctca
    10021 tacttatatg tcggcagaaa aattagaagt aacagcaaga aatctaaacc atcaagcaaa
    10081 attcgaaaca caaggtgtaa aaacagaaaa tcagttatct gaacaagaaa tcaaagaggc
    10141 agatgcaatc attcttgcag tagataaaga aatcgaattg gaccgatttg ccgggaaaaa
    10201 agtaaagcgt gtctctacaa gccgagcaat caaagaaccg caagtagtaa tagacgaagc
    10261 attgagagat attggcgtat tcgttgtgtc taatgaaaaa gaaccagctg caaatgagaa
    10321 aaagccgaca atctataatc atttcatgaa tggtgtgaat tacatgcttc catttgtgat
    10381 cgcaggcgga atcatcatcg cactgagttt tgcctttggg attacagcgg ctgatcccaa
    10441 ctcagcagac tataatgtgt tagcagctgc attttcaagg atcggaggag atacagcgtt
    10501 tgccatgatg gttcctgcgt taggcgcggg gattgctaca tcgattgctg gaaaagcagg
    10561 ttttgcccca ggaattgttg ccggattact ggcctctaca ggtggttcag gttttcttgg
    10621 cggaatgatt ggtggcgtgc tagcagggta tatctgtgat tttctggcaa ataaaattag
    10681 cgtaaaaaaa gaattttctg ctatttatca gctgattgtc gtcccctttt tatcgatctt
    10741 aattattggg cttttgatgg tatttgtgat tgaacaaccg atcacatggg tgttggatgc
    10801 tttgacaaat tggctgaata gcttgggaaa tacatccggg ctattgttcg gattacttat
    10861 cgggatcatg atggcagctg atatgggtgg gccgatcaat aaatcgactt cgactttctc
    10921 gatcggtttg atgtcagctg gagtaaatgc accgattgct gcttgtatgg ctgcaggaat
    10981 gacacctccc ctaggtattg ctttagccac tttattattc aaacataaat ttaccaaaga
    11041 agaacggact tcaggtcaat catgctggat tttaggcgct tcgtatatta cagaaggtgc
    11101 tataccgttt gcggtatctg acccgatccg cgtgatacct agtttgatga caggttcagc
    11161 agtcgctgca gggatttcca tggcagtagg agttacttca atggcacctc atggagggat
    11221 ttgggtgatg ctaattccaa atgttatgaa caatttacct atgtatgtct tggcaattgc
    11281 atcaggtaca gtcactacag cctttatgct tggactattg aaaaaaacag tgaaagagaa
    11341 aaaacaagac aagtggacga aaaatgaaaa tctaacaaat gaggtggaag cgtaatgtta
    11401 tatacaatga aagagttatt gaaagtggct aaagagaatc aatttgcagt accagccttc
    11461 aatatttgca gctatgatat gatgaaagca atcatcgaag aagcagagag attagaagca
    11521 ccagtaatct tagaaattca tcctgatgaa atcgcctatt taagtgatga gtttgttgcg
    11581 gcagtaagag cctatgctta tacaagtaaa ctgccgatcg ttatccactt ggatcatggc
    11641 ggtacgatag aagatgtctt acgggcgatt cgaaacggct attcttccgt gatgatcgat
    11701 gcgtctttga aatcattcga cgacaatgta cagattacga aaaaagtggt tgcgttagct
    11761 catgcggtaa atgtctcagt ggaggctgag cttggaacga ttgggaataa tggttctgct
    11821 gaaggaggtg ctgaaacaat catttataca gatcctgatc aagcgaagat ttttgtgaaa
    11881 gaaacaggaa tcgatacact tgctgtagca attggaacag cgcatggctt gtatccgaaa
    11941 aacagaactc caaaattaaa tatcgactta ctgaaagaat tgaaccaaca aatcgatctt
    12001 ccatttgttt tacatggcgg ttcaggtaat ccggacgcag aagtcagcga agcagtaaaa
    12061 tacggagttg ccaaagtgaa tttgagctca gatcttaaaa gcgtcttttt caatgctttg
    12121 agagaaatat tgagtgaaaa tccatcgatg tacgagccga atgcaattta tccagcagct
    12181 aataaaaagg tacaagaagt ggtcaaacat aaaatggaaa ttttgaacac agtaggcaag
    12241 gctagtttat actaaaaata aaaatgtgtg gtcaagaggg tatgacaata gtcttgtcat
    12301 accctcttaa ccacacacga tgttcagaag tagttttttc gaaaaatttc ttcttatttc
    12361 tcgaagccaa tcacttctgt cacaacctct tttttcctgt tactatataa agtaaatggg
    12421 gtgattttat gttgaatgaa gtggagaata gacagcagga gattgtgaat tatctaaaaa
    12481 acaaccaatt tgcaagagtc accgatttga tcgagttagt aaattatagc gaagccacga
    12541 ttaaacgtga ccttgttttt ctggaaaaaa gtggattgat ccgtagagtt cgcggtggcg
    12601 ccatgcttat tgacaatcga aaaattgacg tgccttacct gatgaagatc accaaattag
    12661 aagaagaaac agaaaaacgt aagattgcag atacagcttc ttctttgatt cgagatgata
    12721 tggtcttatt cttggattcc agtacaacct ctttacactt agtcagaaac ctagcaagat
    12781 ttgatggttt gcagatcatt acgaatggca tcgtcacagc tgctatgttg agtgaatata
    12841 caacggcaaa agtatctgta ttgggagggg caattgttcc gaaacgagca acaatcaacg
    12901 gttcaaaagc ctataacgat gcattgtcat attatgcgga tttagcgata atgagttgtc
    12961 gcgggctaga tttcagccaa ggagtaacag aaactcatga aggagaggca atggtcaaaa
    13021 aagcttttag aaaacaatca gaccggcttg ccgttttagt tacacagcaa aaaattgcac
    13081 ataaattcat gcatcaagcc attgcttttc atgaaatcga ttatctggtg acaagtaaag
    13141 aactgacaaa agaacagtat gcgaaagtaa aggaacacca tatcgaatgt ctgtacggat
    13201 aaattattac gtgaatgttc taagtggctt cctcattttt agataggacc ttatctttgc
    13261 tcgcttctct cagccgatgg tataataatg aaaaggttat cttgttagat aatcttactt
    13321 ttttatccag gagaaaggag tgcagaaaat gaaacatgtg aaggcgttgg tagtgaaggc
    13381 aatcatgatc tgggcgattc tgtgggtcgt gctgacaggt ttatacggtg ttagctttat
    13441 ggattcaacg attgttgggg taattattgt agtcatgatc tatgtgctag gggatctgtt
    13501 gatcttacgt aaagtaggga acatcgcagc gacgatcgca gatgctggtt cagctgcagt
    13561 tatcttgtgg ctctatctat attttatgaa tgatacagtc gatatttgga tgaaagtatt
    13621 gattcctgct ctattgatcg gtgtggcaga atggttcttc cacaagtggt tgctaagtca
    13681 aggcatcgta ccagatgaac ggaaaatgga ataaatcaac agttaaacta ttcttatcga
    13741 taaatgaaag ctttaaaaat aaatagatgt ttaattaaga ataatcataa actattttta
    13801 ctcaaaaaac cgctcagatt attttcagat ctgaacggtt ttttttatct attcatcaag
    13861 atcaaatttc atttttcaat gattcaatca attcgccctc tgcttcatga ctatgttttc
    13921 ggccattaac aagatagagt gctgtacata tcaatggaat gactccggca atcacataca
    13981 atcctctaaa tgaagtaaga gattttagca tccccatcaa ataaggacca acgcctaagc
    14041 ctaggtctaa accaataaag taggtagata aagcaatact gattcgatgt tcgcggacga
    14101 tttttaaaca aacagcctgt ccatttgaca taaacgtacc ataacctagg ccgactaatg
    14161 ctccagagat aagcaatgtc acactattcg tcgttacact cagtaaaaat aatcctgctg
    14221 ttaagaataa atagctagga tacatcacgt attgttctcc tttgacatcg aaaatccttc
    14281 cagtcaatgg acgtgtaaat gtgatgacca aagcatatac gacgaagaaa aatgacccag
    14341 cagcaactaa gtggattact tttgtataag aagataaaaa tgataaaaca cttgaataag
    14401 aaagacccat caaaaaggca attcctgtaa tgaaaagtgc tttcttttca ataaaactat
    14461 tgatattcca tgagcgaaga gatatttttt gttcttcaga taatggaata ttttttacag
    14521 gaaagacaag gcaggcaatc gtaacaaaga agaccagtac aattgaaaac cagataatga
    14581 aacgaaaatc agtcatattc agcaaaatca ttcctaaaaa tggcccaaca gcggcagcta
    14641 aactagtact taatccataa taattgatgc cttccccttt tttagatgca gggatatatg
    14701 cagtaacgat agcatttgta gctgtagaaa ctgtaccgta gccgaatcca ttcaagaatc
    14761 gaactaaata caatgccccg atagttggcg tataaagata tgctaatgtt gaaaggagat
    14821 agaagatcgc gccgcctctt aaggtaaact tccgaccaaa tagttctaac tgtttcccca
    14881 tgaataagcg tgccagcaat gttccgatga tatagatccc agaagcaaaa cctgcttggc
    14941 tcaagctggc gtgtaaggtg tcttgcgcaa tgactgccat gatgaccatc aacagataat
    15001 aaatcaggta gacaataaaa ttgatcaatg tgattccaat aaaatattta ttaaataatt
    15061 tcttttccat gtatgttata cattcccctt aagctgaata tgcttttaat ttttgtattt
    15121 gaacttctac atcgtgataa ttggatggat agcgatcaac aagttggcga ataaataaat
    15181 ctcttgtaga cataaacaga tttaaaaatt cttcgcattc gtttgttgga ttctcatcca
    15241 ctgctttgat caattcgatc gagttttgat acgcatcatt taaaaagact aaagaagctt
    15301 tcatatcaaa tcttgtttga tatgctgttt ctaatcgatt aatgattgtg ttcatccagt
    15361 aattcatgtt ttttccctct attcttaaaa aattttactt ctgcagtata acgaataaaa
    15421 aaaaggaaaa aaatcgcata agtgatggaa aaaggtactt aacaaatgtt aatatcatta
    15481 gtaaaatacc tttggacttt aaaaagtttt aaagtactgt atgatctttt tagatgaaag
    15541 tttggatggg ggagcatcat tggatagtag agtcttaaag gaatatttgg ataaaaatga
    15601 ttttccgatt atacgcaaag gatatcataa atatttgaca ttcgaaggga tggaagattc
    15661 ccatacgtat atcttgaaag agggaacggt aaaagcaagt gttatttcaa atgatgggag
    15721 agaatttaac cttcgctata tcaaagatct tgaaatcgtc tctcttttaa aagacgaata
    15781 ttcacaattc atcgattcgc cgtataatat tcgagttgaa tcagaatatg cagagtttta
    15841 tcgaatcaat cgtgtgcgct tttggcaaaa tatcaaccaa gacccaaagc tacaacacta
    15901 tgtaaaagag tattaccgct atcgtctgct ttattcgatg aaaaaaatgc agcaaatgct
    15961 attaaacgga aagctgggag ctgtttgtac gcaactttac gaattatatg atttattcgg
    16021 tgtgcggaca gaagaaggga tgctgatcga tttttcgatc acgaatgaag aaatcgccaa
    16081 attttgtggc atctcaactg ctagcagtgt aaacagaatt ttaaaacaac tgaaaaaaga
    16141 tggtattatc accgttaaag accatcatat cgttattttg aatatggact tgttagaaga
    16201 caatattatc ttttgatgaa caaagaggtt gtgaaatcag cgttttgacc tgagtattag
    16261 agaaacaaac ggaaaaatag ttcctcatat tttgccgttt tttgagctaa taccgagggt
    16321 cagctgattg aacaccgttt accaagaggt tgtgagcctg ccgtttaact ctgagtcaca
    16381 aggaacaatt tcaaaaaaca gcttttcatg tttgatgaat attgtgactt gtgaccgagg
    16441 agttggtagg agaacaccgt ttaccaagag gttgtgaaaa agctgttctg catcaagtaa
    16501 taagaagagc caagtaaaaa cagtctctta tgtttttaac ttggctggac ttatcaccgt
    16561 agatgtaagc ttttgaacgc cgtttatttg caacaaaagg ggctgtgaca cgatttttgt
    16621 cacagccctt tttttgcgaa cattcattta gcaattttta gaaacttctg ccgccaccgc
    16681 caaaagtccc gccaccgcta gaatgggtag tacttccgcc accgccgctt ccaggaggtg
    16741 ggcttttggg gattcttctt gtcgtgacaa aagaatttgt cagacgatcg gttttttcag
    16801 ttaatttgat actggatttt tctcggaatg gatatttgta gatgcctgat ttcaattgat
    16861 aacgcgaaac agtcacaaaa taaaagacaa gactaaggat aagagccaaa acaacagcaa
    16921 tgatgatttc tactgtcgtc aaaaccttat agcgtgtaat tttgccagtt tcttcgtcta
    16981 cacgataatg tcctcctgga actccgtctt ccacatatgt tgctgattta gacaggtaag
    17041 cttttgcagc attgtaatag gcagcatttg tcatctgatc ataaacatca tctaagatcg
    17101 aatcgattct gctatcagtc aaataatcga tcatattacc agaagtcgaa atgtagattt
    17161 cacgctgtcc catatctaat agcaatactg agccattttg atcatttccg actgcgtctc
    17221 ttaagtaatt atcagcaaag tctcttggtt cttctgaatt agatgtagtc gttacgatca
    17281 agactcgtcc tttgattttt tcattcagct tttctgcctg ttgttccaaa gattggattt
    17341 gatctgttgt gaataaccca gcctcatcat ttaccgtagc tgtatctgca tgagtagcca
    17401 ccggccagcc aacacttact agcaaaagaa agaataaaaa aaattttttc atcatatcaa
    17461 gtaacctccg atcagaaaga ggatcgctag cccagcgaaa atcccaagag cggtcagtcc
    17521 caattttttc tggctgatcg gcaggacacc gctgaccttt cctgtttgtc cattcattgc
    17581 gtagtagtag acttttttac ttgagtcatt gcttcgataa gtaacaagcc ataccggcag
    17641 taatacgtaa ttatttactt cgtttgtgat tgaagcagaa gttcgcacac cggtcaatgt
    17701 tgtatatcca tttgcggtat cttttaacag cttctctgaa tagtctttta attcagattg
    17761 aatctgtgat ttgattgcct catattcgat atctcttttt tctgcttgga acccggctaa
    17821 atactggctt ttaaaatcaa ttgctttatc taacgggaaa ggttgcacgc cttcgaccat
    17881 cttttgttgc gtattttttg ataaggcatt ttttactagt tctttaaaag aaagcttgcc
    17941 tgctcttgaa acagcaaatt gcttcgtttc tgtgtattcg atgtcaccta tccgccatat
    18001 gcggataact gtaccattcg cctgcatggc accatctact tcagcatctg tagcccaata
    18061 agggaaatac acacctgtca acttatcgat ttgatcctta ttgaaaaaag ctttgggaac
    18121 aaaccatttt ttcttggtcc aagcgagaaa tctgttgatt gcttcttctt tctcgacagc
    18181 aaaaggaagt actttatttg gcaagaattc tccgcttaaa cgtcccgata gtacgacggg
    18241 attatggcag tagtaacaat aagtcgcagc agttgtcgca tcagtcacga tctctgcacc
    18301 acagttggga caaagaaaaa gatctatcgc tgcggtatta tctgcagatt cgtccgctgt
    18361 atctgaaaaa ccgcctgcct cgtcaaccgc tttgcgctcg gcttcattca tatcggcaag
    18421 ctgttcttgg gctgtaaaag taaaatcttc ggtaggtgaa ggttcttctt tgctttcttc
    18481 gccagccata cgcgcttctt tttgcttttg ctcatattgg ctgacttctt cttctgtata
    18541 gatattcagg cagtattcgc aatgaaattt ttggtctttg ggatcaaaag tcaacggacc
    18601 gccgcaatta ggacatttat gtgtaagaac atccatcagc tgcacacctt tctaaataaa
    18661 ttaattaacg gggattcctt taaacggttt accacagttt ggacagaatt tagggatgcc
    18721 gttggaaaga tccacgatct cattgcattc actgcatcgc atttgtagct taggctgaac
    18781 gttttctaca ggtttggcag ctccgcagtt ggaacagaat tttccggaat tttctgtccc
    18841 gcaaactgga catgtccaag tatccgcatt tccttgtgca gtttgttgat tttgtttttc
    18901 tgcttgttgt ttgatttgtt cttggttatt ttgagctgct tgagaaagat aagaaccatt
    18961 tgcattcatt cccataccta cacccataaa gccggtcatt gctcctgctt cattttttcc
    19021 ggctgcttcc ataccacgtg caatggaacc ttgcacgtag ccttcacgta cgctaggatc
    19081 acctagcatc gccccttcgt tacgcatatt gatcagtttc acagaatcat cggtgtaaga
    19141 aatgctggct acagccacag aaacaatctc catcccacgt aattcacgcc aagaatcatc
    19201 caatgcagta tccatgtatt tgcttaattc caaactctta gatggtacat aagaaatccg
    19261 ttgaccatct gcagacatct gattgattgc tgattgtagc gctgttagga attcagctaa
    19321 atactgctca ttgatatcat tgatttccac ttgtgttttg tttttaggga ttgcgtttgt
    19381 ataaaataaa atcgggtcaa cgacatgaat agaataagtg ccatgtgccc gtaagaataa
    19441 ttctgcgtta tagaaattgt caaagtagtt caacggcgcg cttgtaccga atttgattcc
    19501 ctttatttct tggagattga tataaaaaac ttgttgtttc tgcggtgtga cgccgccaaa
    19561 tttgaatcgg tcaaaagttt cagcaattgc ttctttcagt gttccattga acatggaagg
    19621 agctgcgtca tttttaatgg tgtaataacc ttcctcagcg gtataatcga tgatttttcc
    19681 accatcgacc aaaagcatca tcatgtttgg atagacatgg acgactgttc cgtctgttaa
    19741 aacatcttct gttcctttac gattggagcc acgtttgtca tctttgcgga ctttgacacc
    19801 ttttgtcatg accgttgtat cactcatatt gtctggttcg atgacttcta gccattgatc
    19861 tgccagaccg ccgccaacca tacttgttgc tgctttgata agacccataa aaaattcctc
    19921 ctctgattca gctagtgcca aacaattatt gtttatttat tataccatag gaagatgtga
    19981 aacttctcgg actagagacg gaattgaaat ggaaaattgc gtattgttta aatacctgaa
    20041 aaagccgaga aggatagtag tttttttacc taatatcacg tataataaga gatagtgaat
    20101 tttttaaaaa agggggatcc ttatggcata tcaagcactt tatcgagtct ggcgttcgca
    20161 gcgtttcgaa gacatcgttg gacaaaaagc tgtgacacag acactaaaaa atgctattgt
    20221 ttcccacaaa acctcacatg cctacttgtt tacaggaccc agaggaaccg gaaagacgag
    20281 tgcagcaaag attttcgcaa aagcaatcaa ctgtccgaac agtaaagacg gtgagccatg
    20341 caacgaatgc gaaatgtgtc gatcaattac tgctggtacg caagaagatg tgatcgaaat
    20401 cgatgctgcc agcaataacg gagtcgaaga aatccgattt atccgtgatc gggcaaatta
    20461 tgcgcctaca aaggcagcgt acaaagtgta cattattgat gaggtacata tgctttcaac
    20521 aggagctttc aatgccttgt tgaaaacatt ggaagagcca aaagaaagtg tcatattcat
    20581 cttagcaacg accgaacctc acaaaatacc agctacgatc atttcacgga ctcagcgatt
    20641 tgattttaaa cggatcaata cggcagatat tgtcgaacat cttgaattta tcttgaaaga
    20701 atcgactatc agctatgaac cagctgcatt gaatgtgatt gcccgttctg cagaaggcgg
    20761 gatgcgggat gcattgagta ttcttgatca ggcaatctcg tttagtgaag gaacaattac
    20821 tttagatgat gccatgcaag tgacaggtag cttaactgac gaaatgatgg acagttactt
    20881 gagtgcttgc gtgaaaaaag aagtaccaga agcattggaa acattgaacc aaattctcgc
    20941 agccggcaaa gaatcacgtc gctttctaga ggatatgtta caatactgcc gtgacttgct
    21001 gatgtatcag caagcaccta acctagttga ggaacaatcg agtacgatca gaagtacatt
    21061 tacagaattg gcacaaactg tttcagcgga tcagctgttt tcaatgataa agattttgag
    21121 cgatactcaa aatgaaattc gttttaccaa tagtgccgct atttatttgg aagtcgctac
    21181 agtcaaactt gcacagctac cgtctgcttc tgttccttca gcagatgtag catttgcaga
    21241 tgatcagata gtaaaacagc tacaacaaga gattaaggaa ctaagaaacg aaatcaagga
    21301 actacgcagt aatacaggaa ttgagaatac aaaagtacag ccggtacagc aaacaaatca
    21361 taaaaaacag acaagtacct atcgtgtacc gacggaacga gtatataaag ttctgcggga
    21421 agcgacaaga cagcatctga accaagtaaa agaagtatgg gaagacttgc tgatgagtct
    21481 atctgtcact cagcgagcaa tgcttaaagc aagcgaacca gttgcagctg gacctacagg
    21541 actagtgatt gcgtttgatt atgagattgt ttgtcaaaga gcagcaaatg acgaagaatt
    21601 gcagctttcg gtacacaaca acttaagccg aatgatcaaa gattatgcgc ctgatcctgt
    21661 ttatattaca agagaaagct ggccagaact tcgaagaaat tatttgacgc aggcacaaga
    21721 agagggaaca gaaaactctt ttgcttctga agactcagaa ggagaaatcg agttgcttcc
    21781 tcaagaacaa gaagtaccag aagaaacact tgtagtaaaa gcagaggaac tgtttggctc
    21841 cgaagctgtt acagtggtag atgattaata aaaaggagta gataattatg atgcgtggaa
    21901 tgggcaatat gcaaggcatg atgaaacaag tacaaaaaat gcaaaaagaa atggcagaag
    21961 cacaagagct gctaaataaa acagagttta caggtaaagc caccaatgaa ttggtcaaag
    22021 cggtttttac aggcgatcgt cgcatgaaag atatccaaat caatgaagaa gtcgttgatc
    22081 ctgatgatat cgagatgctt caggatcttg tcgtaatggc agtcaatgat gcgatcgcac
    22141 aaattgatgt ggaaactgag aaaaaattag ggaaatacgc aaaaggtttg ccaggatttt
    22201 agttttaaac tgaaggagta atgaatatgc aatatccaga accaattgcg aaactgatcg
    22261 acagctacat gaaacttcca ggaatcggtc agaaaacagc gacaagactc gccttttata
    22321 cgatcgatat gaaagatgaa gtagtaaatg aatttgctaa atctttgtta agtgtaaaac
    22381 gcgatttgca tttttgtagt atctgcggaa acatcacaga agaagatccc tgcgaaatat
    22441 gtagaaatcc ttcacgtgat cgaagcgtta tcctagtggt cgaagagccg aaagatgtaa
    22501 tggcaatgga aaaaatgcga gaatatcacg gactttatca tgttctccat ggtgtgttat
    22561 caccgatgga agggacaggt ccagaagaca tcaatatttc ttctctgttg cagcggctgc
    22621 atgatgcaga tgtaaaagaa gtgattatcg caacaaatgc aacaacagag ggagaagcaa
    22681 cagctatgta tctctcacgt ctgatcaaac ccgcaggtat caaagtgact cgtctagcac
    22741 atggtctgtc tgtaggctct gatatcgagt atgcagatga agttacttta ttgaaagctg
    22801 tcgaaggaag acgtgagtta taaatttcta attaagtgtt ttttcagata caatataaaa
    22861 gcagcacaag agatgggggc aacaatgtga acggactatt tattacaatc gaggggcctg
    22921 atggtgcagg aaaaaccagc atcttgaatg aactttaccc tcttttgaaa gaagtagcaa
    22981 aaacagaaat cattcaaaca agagaaccag gaggcattcc gattgctgaa gagatccgag
    23041 cagtgatcct tgatccaaaa aatgatcgga tggatgaacg tacggaagca ctgctttatg
    23101 cagcagcaag aagacaacat ctagtcgaaa aggttctgcc tgctctggca aaagggaaaa
    23161 tcgttttatg cgatagattt gtcgacagtt ctcttgctta tcaaggtgca ggccgacgca
    23221 tcggcgttac cgagattgct cggttgaatg agtttgctac agaaggtact acgccggatt
    23281 ttacccttta tcttgacgta gattcagaca ccggattaag aagaatcaag aaaaacagac
    23341 aaaatcaaat cgaccgttta gattcggaag gtttggaatt ccaccagcgt gtacgtcatg
    23401 cttacttaaa gctggcagaa gagaatccgg aaagaatcca caaagttgat gcaagaaaaa
    23461 gctttgaaga agtgctgcaa acaagttatc atacaattat tgaacagtat ccgcaatttt
    23521 ttgaaaacta ggaaggtgaa cgtttatgaa aattatttta gcgattatcc aagacaaaga
    23581 cagcaaccgt ttatcaaatg aattgattga tgcaaatatc cgtgccacaa aactatcatc
    23641 gacaggcggc ttccttaagg ctggaaacag tacgtttatc gtgggtattg aagatgaccg
    23701 tgtagaagaa gcattggaaa tcatcaaaaa aacgtgtgaa tcaagaaagc aatttgtatc
    23761 tacacctgtt acactggata tttcgatgga tgggggcgtc ccttatccag tagaagtaga
    23821 agtaggcggt gccacagtct tcgtcttacc tgttgaagga ttccatcaat tttaggagga
    23881 gctgagctat gaatcaagaa ataaacttgg ctcaaatgca accgatcgtg tatcagcagc
    23941 ttcaacggag ttttgagcat gggcgtatcg ctcatgctta tctttttgaa ggggagaaag
    24001 gaacaggaaa acatgaagta ggtatatggc ttgcacagca cctgttctgt acccaaatga
    24061 aagacaatct gccttgtgga aaatgcaaca attgtcagcg gatcgaaaag aaagaacatc
    24121 cagatgtttt ggttattgaa ccggaaggac aaaccatcaa agtcgatcag atcagacgtt
    24181 tgcagacgga attcagtcgc agcggttacg aatcaagaaa aaaagttttt ttgatcaaag
    24241 aagctgaaaa aatgaatagc agtgcggcaa acagtttgtt gaaattcttg gaagagcccc
    24301 ctggagattt tttagcggtg ttagaaacag atgcagtagg aagaattctc cctactattc
    24361 aatctcgttg tcaagttctg cattttcaag aactttcgaa agaagcactg atccatcgat
    24421 tgcaagaaga gcagattcca ttggaaaaag caaaactttt ggctttctta acaaacagtt
    24481 taggaaaagc agttgaaatc tctcaagatg aatggtttaa tgatgctaag gacttgattt
    24541 atcaatggtt cgtttacttg caaaagcaag atactcaagc ctttatctat gtccaaaaaa
    24601 aattggtaaa atcatttaaa gaaaaaacac aacagtttac aggattatct gtcttgatgt
    24661 tttattatca ggaagcacag cgtcaagcag tagcaaacgg cgaatatggc aaagtgaaac
    24721 agataaacca gataattgaa cggatattga tcgcagagca gaaactacgc agcaatgtca
    24781 gttttcaggc tgttgcggaa cagttcgttt tgcatacgat tttttagctt gccgcaaagg
    24841 atgatgatca aggaggatgg aaatggtaga agtagtaggt gtccgatata gagatgcagg
    24901 tcatatctat tattttgcac caggagactc tgaatatgtt tatagtgaca aggtattagt
    24961 cgaatctcag caatccttac atattgctac tgttgtcctt cctaaaaaag agattgatcc
    25021 caatgacctt cctgaagcta tccgtccgat cttgcataaa gcgtcacaag ctgaattaga
    25081 aaaagacaaa aaaaacaaaa aagatgctta tgatgcattg aaaatcgcaa aagaaaaagt
    25141 gcagttgcgt gagttggaaa tgaaaatggt caaagccgaa tacacatttg atcgaaataa
    25201 attgattttt tctttcacag cggacgggcg aattgacttt agagaattgg taaaagatct
    25261 ggccgctgta tttcgtactc gtattgagct tcgacaaatt ggtgtccgcg atgaagcaaa
    25321 gataataggc ggaattggtc catgtgggcg tccattatgc tgttcttctt ttttaggcga
    25381 tttcgtgcct gtatcaatca aaatggcaaa agatcaaagt ttatctttga atccaacaaa
    25441 aatttccggt ttatgcggac gcttgatgtg ctgtctgcaa tatgagagcg aagaatacga
    25501 tacagcgaaa aaagaactcc ctgactttgg aaaagtaatt gctacacctg atggtaaagg
    25561 gaaagtcgta gggttgaatc tgcttagccg tatcgttagt attcggctga ctggacggga
    25621 aaatcctgtc gaatatgaat gggatgaatt gaaagaattt atccaagtag gtgagatgaa
    25681 tggataagag atcattatac gacggattga atcaattaga atcagagttg agaaatacat
    25741 taacagaact tgttgaaatg aagcatgctt tgcatgagat cgtagaaaaa aatacaactt
    25801 tggagatgga aaatcaacgt ctgcgggaac acctgcggga attgaaccaa gttgcacaag
    25861 ctccagctga aaatgtgaag caggaacttt ctaagtctcg tatgaatctt gaaaaaattt
    25921 atgaagaagg attccatgtc tgctacgatt tatatggatc aagaagggac aatgacgagc
    25981 cttgtgcgtt ttgtctagaa gtgatctatc gcgaaagcgg tcgatgacca ataacaagag
    26041 gagactggag cggagaaata ctgctccagt ctttttatta aggagattgt gacagatgta
    26101 taatcaaaaa agtttcaagg gaaatccggt atatggggat ttatatcttg taccgacgcc
    26161 aattggaaat ttagaagata tgagctacag aagtgttcgt atgctgcaag aatccgatct
    26221 tatcgcaagt gaggatacgc gtaatacaca aaagttattg aatcattttg aaatccatac
    26281 accccaaaaa agtttacatg aacataatta taaagaacgt gtccctcaat tgattgcttt
    26341 gttaaaagaa ggaaaaacga ttgctcaagt cagtgacgca ggaatgcctt ccatcagcga
    26401 tcctggacat gagctagttt tagcctgcat aaaagaaggg atttctgtga tctctatccc
    26461 aggacctaca gctgggatga cggctttgat tgcttcaggg ctagtgcctc aaccattttt
    26521 attttatggc ttccttccac gtaagaaaaa agaacagaaa gaaacattga aaaagctaaa
    26581 agaacagaca gttacgctga ttttttatga gtcaccttat cggatcactg ctacattgac
    26641 gaatttctta gaaatttttg gaaatcgcca agtcgttttg tgtcgggaat tgacaaaggt
    26701 ccatgaagaa taccttagag gaagtacgga agagctactc gcttatatcg aagaacatcc
    26761 agtaaagggt gaatgttgtc tgcttgtaga agggaatttg ttcgaaatgc cagtgacgga
    26821 agttgatgaa gagttgggaa cgttaaagga acaagtagaa gcaaagatcg cttcaggcga
    26881 aaaaccaaat gctgctatca aagcagtagc gctgaaaaat gggctgaaaa aacaagaagt
    26941 ctaccgtcag taccatgaat tagactgaga tagtataagt tgtctataat gaaagactaa
    27001 tgaggaaatc agctactaac ttttcaaatc tcttgaacgc gaacgaatgt tcttgtataa
    27061 tgaataagag gtgaggatga tggagctgca atttccttta cataatgata catcaagaaa
    27121 aatcattcat attgatatgg atgctttttt cgcttcggtt gaagaacgag atcatcctga
    27181 gtttcgcgga catccattag taattgccag acaccccagt gacactggtg ggcgtggagt
    27241 agtgactaca gcaaattatg aagcaagaaa attcggaatt cattcagcaa tgagtgcaca
    27301 aaaagcgtat gagctttgtc cgcaagccat ctttaagcct ggcgaccatc ataaatacag
    27361 cgatatttcc aaacaagtac gggaagtatt ctatcgttat acagatattg tggaaccagt
    27421 tagtatcgat gaagcgtatc ttgatgtgac cgaaaataaa atcaattgca agtcagccat
    27481 caaaatcgcc cgaatgatcc aagcagatat ttgggagagt gtccagctaa catgttctgc
    27541 gggagtaagt tacaataagt ttttggccaa attagcatca gactatcaaa aacctagagg
    27601 aatcacggta gttgcccctc aagacgctgt gccattttta aaagctttgc caattgaaaa
    27661 atttcatggg gtagggaaga aaactgtacc tagaatgcat gagctaggga tttatacagg
    27721 aaaagaccta tatgaatgca cagaaatgat gttgattcga aattttggaa aaatgggcta
    27781 ttctctttat cgtaaagtca gaggaatcca tgattctcca gtaaacgtta caagagagcg
    27841 aaaatctgtg ggaaaagagc atacttatgg gcagccgttg caaacggaag aagcagtgct
    27901 gactcagttg cgccaactag ctgaaaaagt agaagaagca ctgagaagag tccaaaaaca
    27961 tgggaaaaca gtagttttga aggtcaggta cacggactat tctactgtga ccaaaagagt
    28021 gacattgcca gaatatatct ataaaaaaga agcactcttt tatcaagcaa gccttatatg
    28081 ggaggaaatc ttgggagtag aaaaaggaat ccgattgtta gggattactt tgacgaatct
    28141 ggacccgatg acttatgaaa acatcgtcct tccattatgg gaaaatcaag aaatataaaa
    28201 acagctttga gagttgaaac cggaaatccg ttttctctcc caaagctgtt tttatatcaa
    28261 gtcttgcttt ttgatttgtt cataggtttc tgttgcatcc gtacattttt cccaaatcac
    28321 aacttgattg gattctaaag atttttggac gtcaatgatc cgctggttgc tacttccgcg
    28381 aaattgtagt tttaggtcac gtttgcttaa ttcaaagcgt ccgtcaacaa ggatatcgat
    28441 ttgcgaaagg agttctaatt tatcttctga atcttgtagc aattcatcaa aggtatagcc
    28501 tgtccatgac cagatatctt ttgtcgtacc gaactctttt cggatacgtc gtacgacttg
    28561 cagacaaaca tctgtattca aaaaaggttc gccaccaagt aaagttaatc cttgcacgta
    28621 atcgttgcgc aagtcagcga tgatttgttc ttctaattca ggtgtgaatg gtttgccata
    28681 tcgaaaattt tgtgcagctt tgttgaagca gccttcgcag gcaaataagc agccactaac
    28741 gtaaagactg ttgcggacac cttcaccatc gacaaaatta aacggtttgt agtcagcaat
    28801 atagttttgg ctgtagtctt ttgctaacca ttcttttggt tttggatttc tcataaaaaa
    28861 acttctttca tttaaggttc aaagatatag ctattgaaga taaaatctac tcgaccacat
    28921 aaataagaac aaactgacct aaatccattg ttcaagaaag cttgttctta ttttgataga
    28981 gggcgttcaa agatacaaag ccatcgaaag agggtggtga aaaaagactt gtcatagcct
    29041 cttattctga ataaacggtg ttcaaaagct tgcatctgca gtaataagcc caactaaacg
    29101 aaaaatatga ggaactattt ttgtttagct attcttatta cttgatgcag gacagctttt
    29161 tcacaacctc atttcatgtg tttcacacgt gaggaaattt ctttatggcg gccatgtacc
    29221 atcggacgag cttgcggatt tcctaaatag ccacaagtac gtttgactac atcacatgtt
    29281 tttggatcat gatttccaca ttctggacat tcgaaccctc gttctgtcgg tttgaaatca
    29341 ccttcgaaac cacattgata gcaatgatcg attggcgtat tcgtaccaag atacccgatt
    29401 ttgtcatatg caaaatccca tacagcttct aaagctttcg gattttgttg gagcataggg
    29461 tattcacagt agtggatgaa tccacctgaa caatattttg gataatcctt ctcaaattcc
    29521 aatttttcaa atggcgttgg gtttttacgc acatcatagt ggaaactgtt tgtataatat
    29581 tctttatctg tgatattttc gatgatgccg aatttttctg tatccaaacg gcagaaacgg
    29641 tcagttagac tttcacttgg agttgaatag acactgaaat gataaccata ttcatccccc
    29701 catgcatctg cattagcttt taattctttg acgatatcaa gtgtgaaagc ttttgcttct
    29761 gggtttgttt cccattcgcc accgaagaaa gctgaagcaa cttcatacaa tccaatgtag
    29821 cctaacgata cagtagctcg acggtttttg aataattcat tgacagaatc ggtacgtgaa
    29881 agacgtttcc cgaaagcacc atacatatat aaaattggcg catttgctgg aatggcttct
    29941 ttacaacgtt ctacacgata gagaagcgca tctttcatga tttctaagcg gtcagacagt
    30001 aactgccaga atttattctg atctcctttt gattcgatcg cgattcttgg caaattcaat
    30061 gtaacaacac ctaaattcat tcgtccgaca tttacttctt gaccattttc gtctttccac
    30121 ccttgcaaga atgaacgaca gcccataggt actttgaaac ttccagttaa ttcaacgatt
    30181 ttatcgtaat tcagaatatc aggatacatt cttttcgttg cacattccaa tgctagttgt
    30241 ttgatgtcgt aattaggatc ttcagggttt aagttcacac cttttttcaa agtgaagatc
    30301 agtttaggga agatagctgt ccgcttttca ctccctaatc cattgattcg aatctgtaaa
    30361 attgcttttt gaatttctct ttcaaaccag ttttctccta gtccaaatcc taatgaagtg
    30421 aaaggagttt gtccatttga agtaaataag gtattgattt catattccaa actttgcata
    30481 gcatcgaaga tatctttttt ggtttttgct tttgcatatt ctttttggcg ttctggcgaa
    30541 tcgatccatt cttccgcgtc ttttagatgt tttttatagt tcaattctgc aaaaggagca
    30601 agcaattcat ctgttcggtc ggcagaacag ccaccatatt gacttgacgc tacattggca
    30661 ataatctgtg agatttgtgc tgtggcggtc tggatagatt ttggcgattc gacttcggca
    30721 ttgccgattt tgaacccatt gttcagcatg cctttgaaat caatcaagca gcaattcgtc
    30781 atcggtgtat aaggatgata atccaaatca tggtaatgga tatcgccttt ttgatgcgca
    30841 tttgctatat gtggtggcaa cattttcagt ccgattgatt ttccaacgat cccggctgtc
    30901 agatctcgct gtgtattgaa aacattactg tctttatttg cgttttcgtt cacgacagtt
    30961 tggtccttgt tgattagctt ttcaatcgaa aagttgatat ctgttgcttt actgcgagca
    31021 aaatctcgtt tggtacgata attgatgtac tcttctgcta attcatattc gtttttttct
    31081 agtaatatat gttccacgat gttttgaatc tcatagattt tgacattttc agcaaaccgg
    31141 cttttgattt cttggacaac caagtctgca atcatttgaa ttttttcata agtaagtggt
    31201 gataatgagc cgtgaatttt cttttctgct ttgatcagtg cttcattgat cttttgttca
    31261 tcgaaatcaa catggcggcc atcgcgtttg atgactttca tctgggatgt ctctggctgc
    31321 tgagtaacga cagttttttc ttcataattt actttcatta tcttcaactc ctgctaaatt
    31381 gttcttgtct atcataaaac aaaatcgggg aaggagcaac taaatatcgg ctatatatag
    31441 tattcaatgt gctgtataat tggatttcta tactatatgt agtgtatatt ttattgtgaa
    31501 aaaaggtgaa aacttgtagc tggtggattt gttttttgca tatttaattt tgctgaataa
    31561 aataattgaa taaaattttt tattcagtcc aagtaaaagt gacaaaaaca taagagcaaa
    31621 ttattcgtag atatgctact atgcaaataa atagaaatga aaaatgaaag aggaggagaa
    31681 gaattggaaa agatgatcga agtgaaacat ctaagtaaaa gctacggcag caaactttct
    31741 cccgtcaaag ccttagataa tatctcattc acagtagaag aaggcgagtt tgttgggatt
    31801 atgggcccaa gtggtgcagg aaagacaacg ctgatgaata tcttgtccac gatcaatttg
    31861 cctacgatgg gcagtgtctc gatccaagga aaagaaatca caaaaatgaa aaacagtgag
    31921 ctcagtgact ttcgtcgaaa aaaactagga ttcatttttc aagagttcaa tttgatcgat
    31981 accctaaatg caaaagacaa tatcctattg cccctagcag ttgaacggat gactaaagag
    32041 gaaatggaaa agagagtaag acatgtagct caattgttga atatagaaga actgctcaaa
    32101 cggtatcccg atgaactttc tgtcggacag agacaacgaa ttgcagctgc tagagcactt
    32161 gttgttcagc cacaagtgat ttttgcagat gaaccaactg gctctttgga ctcgaagtcg
    32221 gctacagaat tgttgaacta cttgaagacc atgaatcaaa aagaaaaagc aacgatactg
    32281 ttagtcaccc atgatccata tacagcaagc tactgcgata gaattttatt tattaaagat
    32341 ggtgtgattt tttctgaagt tgtcagaaga gggacaagaa gagagttctt tgagaaagta
    32401 atagacatgc aggcgacgat tggcggagga ggaaaaatga atgctgtata aactagccgt
    32461 taaaagtttt tttcggcagt cacgaggcta tcttgtttat tttttcagtt tgactttatc
    32521 cgtaatgatc tattattcct tcagcgcaat gacctacgat caatctttag tcagaagagc
    32581 aagtcaagat acttcgatag atggtggatt gagttttggt ggatttatca ttactgttgt
    32641 tttgcttttt ttcgtattca gtgccaaccg atttttcttg aatagaaggc aaaaggaaat
    32701 aggcatctat cagctttttg gtatgaataa actgcagata tcaggtatat atgtgttaga
    32761 aatcatgata attggattgt tcgcctgtat ttctgggata ttactcggta ttattttttc
    32821 caaactcttt tcaatgattt tggttcgaat gatggatatg gatcttacta gtccattttt
    32881 tatctccatt ccatcagtag tagatacttt atttgctttt ttcatcatcc ttttagcagt
    32941 atctgtatat tcaatatgga aaatatggcg ctatccaatg attcgaagtt ttggagaaaa
    33001 agaacaagca gatagttcaa caatgcgctt caggacaagg caccgattac tcgcagtcat
    33061 cgggttacta cttttaacga gcggatattt tggagctagt cattttaggg aaatcacttc
    33121 atggatgatc agttatcatt atcttgatac attagttttc ttttttcctt ttttaatttt
    33181 tttcgtttgt gtggtcggta cttatttgtt tttctgttat acatttcggt tatttttgat
    33241 catattgagt aaatggaaga tttattacta tggtatcaat tttttgataa tgggtaacac
    33301 gcaagttcat ttgctcaaaa gttggcgtac aaattctctg attacagtca ttctcggaat
    33361 ttctttaatg acaattggcg gcacggctag tatctctact attttatcct accaggagaa
    33421 agtttcctcc ccgatggact atcagtttga tgttgagaca gagaaaaaaa tcaagccgat
    33481 tctagcagag gaagggcaga agataactaa agaaatcacc ttgcattata aagtcattgg
    33541 gagtatctat agtcaaaatc tcgaagaacc tatgtttcaa actgctaatc tgatcacgga
    33601 aacacaatat caagccttca gaaaagttaa tccagatttg ccgaacattt ctttgaaatc
    33661 acctggtcat actgttttgc ttgatcaaat gcaaactctt tttcggaata tttcattata
    33721 tggatctagt attggactgc cagataatca agaattgaag attcaacaaa tgcttccaag
    33781 tgtattaggt gacgaaacaa tggtatatct aagtcctgta ctgattgtag atgataccgt
    33841 ttttgaaaaa gcaaaaggtg tggattatca agtagtcaat gtagatgtat caggtggaaa
    33901 taatgaaaaa atagatgaac gactgagcaa tgacctgtcg ataaagtggc tcaatgctgt
    33961 ttattattct tatgatatcg taaatggaag tctacaagga gaaattagca caaagaaact
    34021 tccggatgac caaatgaagg aagcacaatt tagccaagaa agctctcgtt tgaatttctc
    34081 ttccagctat tcgaaattgc gtgcagttaa tcggcgaatc ggtatcaata tttttgtcac
    34141 actatttgtc gggatgatcg tgattattgc tactggtagt attttgacag tccggcaatt
    34201 agcagaagca gaggaagaaa aagaaaatta tcacctattg actaagctgg ggattccaca
    34261 aagaaggatc agacggatga tcttcgagca aaacgcactt accttctttc cacccatgat
    34321 attagggatc actcacgcag tatttgcaat caatgtcttc actcagtata taaaaactgc
    34381 cgattactgg ttggcttatc ttgtgagtgg cttattgatc cttatctatc ttttgcttta
    34441 tgtcattacg agtcagttat attgtcggat tatcgaggaa tgatatacgg aataagacaa
    34501 gataataaat agaactaaat tttgaatacc atttatttgg aataagaggt tgtgacacga
    34561 tttttgtcac aacctcttta ttttttatat tttttaaaag tacgagaaat tataaagaaa
    34621 aaagcagtga tttgatgtgc tatttttata aaagctatgt gacaaaactg ttagtaaaaa
    34681 aacggtttct gtaagctaga cacatgtttc tttttgtcaa aattagttac actttgtgtg
    34741 aggttatatg aggagggaat ccaatgaaca aatggcgttc taatccaaaa ttgaattatt
    34801 ggggaaaatt catcattcga acaatttttt atagtgcagt actgctgttc ctgatttatc
    34861 tgtatcacta taaaaatatt caaggaggaa cttttatcta taacgaattt taggaggaag
    34921 agtatggaaa tcaaaacgat tattgaagca atcgatgatt ggggaataaa tgaacctgat
    34981 cgagttgctt atcaggcgga tgagacgcat acttttggtg aattgaaaca agcatcagac
    35041 gcacttgctt attatttaga aaaaaaggta gaaggcgatg gaccaattgt cgtttttggc
    35101 aatttggagt ttgaaatgat tgtctcattt ctaggggttg tcaaatctgg ccatgcctat
    35161 ttgccgattg aagagcatac acccaaggag cgtatcctat cgatctttcg ggtggctaaa
    35221 ccatctatgg tcatcagtat cggggactgg atagaagata ttccttcggt tcctgtcata
    35281 acaaaaaaag aatttcaaga aatcaagaag ataccagtag gattttatcc cagaaatagc
    35341 gtaaaaggta cagaaaattt ttatattatt tttacttctg gtactactgg agaaccaaaa
    35401 ggcgtacaaa tcagtcatga taatctagtc agctttgttc aatggacgat ggaagacttt
    35461 gggatcaagc ctggtatgca tttcttagcc caagcgccat tttcttttga tttatcggta
    35521 ttttctattt atcctgcatt agtttctggc ggaatgctga agccgttaaa taaagcagtt
    35581 gttcaagact ttcgtcaatt attcgcgaca ttgccagcct tgaagttgaa tgtgtgggtt
    35641 tctactccat catttatgga tatttgcttg atggaaccta cattcaatgg agaaaatgtg
    35701 ccggaattgg acatgttttt attttgcgga gaagaattga cgaaaaaaac tgcagaaagt
    35761 ctacttgatc gattcccaaa tgcacggata tataatactt acggtccaac agaagcaact
    35821 gtagctattt caagtattca gattgaccag catgtactag atagttatga ccgactaccg
    35881 attggctacg taaaaaaaga cacgaaagtt tctattgtcc aagaaggtaa acctgtttca
    35941 aaaggagaaa cgggtgaaat cattattgca ggaccaagcg tatcaaaagg ttacctgaac
    36001 aatcccgaaa agacagctgc tgcgttcttt tgtcaaaatg acttagcaag ttaccataca
    36061 ggggatgcag gtagactaga tgaatatggg cttttatttt atgaaggacg tatggatcag
    36121 caggtcaaat tacatggata ccggattgaa ctcggggata tcgaacatta tctgctccaa
    36181 gacaaccgaa tcaaacaagc tgtcgtcgta ccaaaatacc aaggaacaaa agtacagcag
    36241 ctggttgctt ttgtcgtatt agaaaacaaa acgaaacagc cggattttca gttgactaaa
    36301 tctatcaaag aacaattact agaagttgta atggattata tgattcctca gaagttccat
    36361 tatgtcgatc tgctgcctca gacagttaat ggaaaaatcg atcgaaaaaa attaacagct
    36421 gaggtgaatc ctgaatgatg ttacctcata tgatccctta tgcagagccg ttttattttt
    36481 ttcttttagc cattgcgctt gtaccgatcg ttctatcttt attgatatgg gaaaaaagat
    36541 taccagttta tcaatcagca gtgacacttt tctttttatt tgtcagcttt ggaggtaatt
    36601 attggcaaca gggagcggcg ctgattgggt atgttttgtg gcagacgata cttgtatggg
    36661 gctattttgt ttatcggcaa aggaaaaatc agacaggatg gttttttgcc gccgttattt
    36721 tagcgataat tccactgttt ttaacgaaag tgactccttt ttttgaacat ggaaaagcat
    36781 cgttacttgg ttttttagga atctcttatt taacctttaa atctgtacaa atgatcatgg
    36841 aaataagaga tggcatgatc aaaacatata agccatttcg ttatatccag tttctgctgt
    36901 tctttccaac aatctcttct ggaccaatcg atcgctatag gagatttgaa aaagatcagc
    36961 tccatccgcc tgttcgtgat aaatatgttg atcttttggg aaaaggcgtc caaaatattt
    37021 ttgtcggttt tttatataaa ttcattatcg gttattattt tggtcaagta ctgcttcctg
    37081 tagtgggacg cattgcctta cagcatggtg gtatttcatg ggcattagta ggttatatgt
    37141 acgtgtacag tatgtatttg ttttttgatt ttgctggcta tagcttattt gcagtcggta
    37201 caagctacat gatgggatat cagacaccaa tcaatttcaa taaacctttt ttatcatgga
    37261 atatcaaaga attctggaat cgttggcata tgacgctgtc cttttggttc cgtgattatg
    37321 tatatatgcg attgatgttc ttcatgatga agaaaaaatt ttttaaaagc aagatcgtaa
    37381 tgtcaaatat cggttatttt gctttgtttc ttctaatggg tatatggcat ggattgacgt
    37441 ggtactacat cgtatatgga ctgtatcatg cttgtctgat ctgtctgaca gatgcatgga
    37501 tccgatttaa gaagaagcat aaagagcagt tgccttctaa caaatttacg catggcttag
    37561 ccgtattttt gacatttcaa gcagtatgtt ttagcttcct gattttttca ggatttttag
    37621 ataaactttt ttttagctaa cgaatagtga catattaatt tatataacaa aggagaaaag
    37681 gaaaatggaa gaacaaattt tatcaatctt agaagaaata acaggaacag atgaagtaag
    37741 aaaaaatcgt gatattgatc tatttgatga agggttgctt gattctttag catctgttca
    37801 attattagtc gagctagacg gagagctgga tatccaagtc cctgtatctg aattcgagcg
    37861 agaggattgg tgcacaccga ataaaatcat tcaacaagca actgcattga agggttgagt
    37921 atgaaaaaga aactttttgc tattttcggc ccggttgttt tagctgttgg cttactgttt
    37981 gtgtttttta cctcctccta tcaagtagat atctctaatc cagaaacgat tagacgtgcc
    38041 tcttcttcca tgtcagtgaa cgtgttgaaa ggagatgcga taaaaaatta tgcattatct
    38101 gaaaaacaat atattccttt ttttggctca agtgaattaa gcagaatcag tccatttcat
    38161 ccgtctgttc tggcagaaaa ataccagcga aactatcgtc catttttgct gggagcaccc
    38221 gggacacaat cgttaagcca atatatgatg atgcgttctg caggagatgc tatgaaaaac
    38281 aagaaagtcg tctttattat ttctcctcag tggttcgtta aaaatggtgt aaaaactgat
    38341 tactttaata cgtattattc tgaacttcaa acatacgact ggttgttttc aatgaagaaa
    38401 gtaacgcctg ctgatcgcta tttagctaga agattattaa ctttctcaaa agtaaaagag
    38461 aatgatacgt tgacggcgat tctgcaaacg atcaaaaaag ggaagctacc tttacctgaa
    38521 tctttgaatc agctgcgcag ccaatggaac atgctgaaga gagaggatga agtattcagc
    38581 aatattgggt tgaaagatcg acagcaaaaa atcgatcatg agtcaaaacg attaccaaaa
    38641 caataccaag aaacagaatt atccatttta gcaaatcaaa ttggagaacg agaaacgacg
    38701 aataatccat tcgggttgaa aaacgatttt tatacgcatc gtatccgagc ccacgagcca
    38761 gagctcaaac agtcacaaaa aaattgggat tatcgttttt cgccagaatt ttctgatttt
    38821 cagctggtct tggatcaatt agcaaaaaac cataacgaag tattgttcat catcccaccg
    38881 gttaacgaga aatggagcga ttataccgga ctatctcaag aaatgttaca aggatttgcc
    38941 aaaaagatca aatttcaatt aaatagccaa ggattcaatc gaatagctga ttttgtcaat
    39001 caagcgggta ccaactattt tatggaagac acgatccatc taggctggaa aggctggttg
    39061 gctgcagatc aacagatcag accgttttta gaagaaaatc atattactgc tagtaagtat
    39121 catcttgacg atgctttttt tagcaaatct tggcaacatc aaataccaga taaactacaa
    39181 ttaaaataaa gaaaacaggc gagtgttgct cgcttgtttt ctttattttt gaatattctg
    39241 aataaaagat aaaaatacca agtttgcctg aacaaaaatc ataagcaatg gtataatcac
    39301 aatatgaata tagaaatggg ggaaaacatt tggatacaaa agaagaacag ctacttattg
    39361 atttaacttc tgcaaaagga gtacctggaa atgaagaaga ggtaagagaa gtattcagag
    39421 aatatgccaa accattcgct gatgatattt tttatgacgg tttaggcagt gtgattgcca
    39481 aacatggtgc tggcggaggc cccaaggtct ttatttctgg acatatggac gaagttggtt
    39541 ttatggtaac aaaaataacc gaaaaaggat tcttggaatt ccaaactctt ggaggttggt
    39601 gggggcaagt catgcttgct cagcaagttg aaatcaaaac acgtgaaggg aaaatcgtcc
    39661 acggtgtgat tggttccaaa ccaccacatg ttttaacacc tcaagtaaga aataaacctt
    39721 atgaaataaa ggatatgttc attgatattg gcgcatcaag ccaagaagaa gccaaagagt
    39781 ggggcatacg tcctggagat atggtcactc catatattga atacaaacga atgaatggca
    39841 gtaaatattt actggcaaaa gcatgggata atcgtatcgg gacagctgtt tctctgcgag
    39901 tattagagaa tctatctaaa gaagcacacc caaatgtttt attcgcagga agcgatgtgc
    39961 aagaagaagt aggcttgcga ggtgctcgaa caagtacaca ccttgtaaat cccgatattg
    40021 cttttgcttt agatactggt acagcaggag acactccagg aatgacacca aaagaagcag
    40081 attcgatttt aggaaaaggc ccacagattt tgatttttga tgcatctatg atcccgcata
    40141 aaaaattatt gaattttgtt attgatgtag cagaggaaat ggatattcca ttccaatata
    40201 cagtgatttc tggcggagga actgatgcag gacaaatgca tttgacaaga gatggtgttc
    40261 cgtctgtagc cattaccgtt cctgttcgtt atctgcattc ccatacatca gtgattcatg
    40321 aagatgatta tttgaataca gtgaaactag tcacagaatt agtgaaacgg cttgatagtg
    40381 aaacagttga aaaaattcgg agttatgaat aatgaataat agaataccta tttctgaata
    40441 tcggaaaaaa gcacgagttt ctttggaaaa tcaatgggga atcaatactt ggcttgtttt
    40501 cttatctata atatttacga gcgtcatcca gaactttttt gacggtttca gtccttttcc
    40561 ggaagaaagc atgcagcagc acttattgag ttttctagtc gataatttac ttttattcgc
    40621 attcaactat gcattgtttt acattgcgct agtagttgta cggggtggca gaccaaaaag
    40681 taacctttta ttttcagttt tccaaagaaa gtattttggt tcgatacttg gcatcaattt
    40741 gatcaattca gtcatcaact ggctactcaa cagtttaatc tttctgccca tgtttttaat
    40801 cagcggagtg agtacttata tgcagctgct tttcagttca aatgcggtac ctacgggtgt
    40861 catgccagaa gattttcttg atatcagctt tgttttatcg atgataggga tgatttttgt
    40921 ttcagcactc atcatgagta ttgttggcgg tttattccaa tttgctgcat ggacaaagtt
    40981 cgactatcct gatttgtcgg ttattcaatg tttgaaatat ggctggtttt tattgaaaga
    41041 tagaattggt acgtatattt tgttgcagct gtcttttatc ggctggtatt tgctaggagc
    41101 aatcgctttg ttcatcggtc ttttgtgggt cattgtttat gtgaatgtgt cagttgcaga
    41161 attttatgaa caagcacgga ttgaaaaagg aggtccagac gcctatttta cttagcatgt
    41221 aagcagttta ttcatcaaaa aaataacttt tgtggtagga taaatctttg agggggaatg
    41281 tacgatgaaa ttaactgttt taggatgctt aggagcgtat ccttataaaa atcaagggac
    41341 aacaggttat ttgcttcaat ctgacgggtt caatttgttg atcgatgcag gtagtgctac
    41401 gctgatcaaa ttacaagaac accttgatcc acttgatcta gatgctgtga tccttagcca
    41461 ttatcatcat gatcatattg ctgaccttgg tgtattacag tattactggc aacttcatcc
    41521 taagagaaat ccggagacat tgctttcaat ttatggacac acaaaagatt ccattcactt
    41581 tgaagaattg acgttggaaa atgtctcaaa aggacatcct tattttgaag ctgaagaatt
    41641 aaaaattggt ccttttctga ttacttttat ggaaacaatc catccagtag tatgttacgc
    41701 catgcgtatc gtagaagaaa caacggggaa agtattcgta tttacaggtg attcaggtta
    41761 tttggaaagt ttcgctgatt ttgcgaaaga tgctgatttg tttctagcag atacctatct
    41821 ttttgaagga aatgaacatc atcatgccca tttcacttca aaagaagctg gagaacttgc
    41881 gaaatcagct aacgtaaaga aacttgtact tacacaccta cctcagtttg gtgatttaga
    41941 acaattgaaa aatgaagcgc aaaaggcagc aggcaaaggg attgatatag aacttgctgc
    42001 agttgacaaa gtgtttaaca tttaggagga agaacatgat ttttgtacca aatgaaaacc
    42061 acgacccaag aatcaattta gcaattgaac aatatttgct gcaagaaatg cctttagatg
    42121 aacctatttt gctcttttat atcaatgaac cttcaatcat catcggcaga aaccaaaata
    42181 cgcttgaaga aatcaatcga gattatgtgg aagaaaatgg cattcatgtt gtccgtcgct
    42241 taagtggagg cggagctgtc taccatgatt ttggaaacct gaactttagt tttatcatgc
    42301 ctgatgatgg ggattcattc cgtgactttg cgaaagtaac acagccaatc atccaagcac
    42361 ttcatgaatt gggtgttgct ggggcggaat tgaaaggccg aaatgatcta gtcattgatg
    42421 gcatgaaatt ttctggcaac gcgatgtatg ctaccaacgg tcggatgttt gctcatggaa
    42481 caattatgtt cgactctgat atcaatgaag tagtcaatgc attaaaagta aaaaaagaca
    42541 aaatcgaatc aaaaggaatc aaatcgatcc gttctcgtgt aacgaatatc aaaccatttc
    42601 ttccagaaga aaagcaaaaa atgacaacag aagaatttcg tcaagaaatc ttgttgaaaa
    42661 ttttcggcgt agagtcagta gaagaagtaa aaacgtacga attgactgat gaagattgga
    42721 aaaaaatcaa tcgaatctct gaggaatatt atcgaaattg ggattggaat tacgggaagt
    42781 ctccagattt caatttctct cgccaaaaac gtttttctat cggttcgatt gaagtccatt
    42841 tgaatgtctc agaaggaatg atcaaagaag caaaaatctt tggcgatttc ttcggactag
    42901 gagatatctc tgacgtggaa aaaaaattgg ttggacagaa atatgataaa gcatctctat
    42961 caaaaatagt cagccaaatt gatgtgaaga aatattttgg tgcgatagaa ccagaagaat
    43021 tgcttacctt actttattga aaataaaaaa tagcggaatc cacatatatg gattccgcta
    43081 ttttttatac aggattcggg taatttcgag agagttgaac agtgatccga tcaatgaaag
    43141 tatctttttc ctgcgttagt gttcctgtgt aacgatccgc tacgtctttc atcatcatta
    43201 agtcaaaacg ttcctgatca tctaattctt ctgtgatgcc tcgactaaat aggtttgtat
    43261 cgtaatgtgc actatgttcg caacaaatga cgaaatgttc ctcttgttcg tgtatcgaca
    43321 aataaatttt tcgatacagt ggattttcga tggcatgagt ttctctaaag gaatgctcta
    43381 aagcgtggat caaaagttga gccagatcgt catcgttgat aggaagttct tcgggaagat
    43441 ctgcttggaa ggttatctga atattccgtt tggcagctaa cttctggtaa cgcgctaaga
    43501 taagatttgt cacctggtgg ttgcaaaaag aacacagcat ttcgaaattt tttgcttctt
    43561 ctaatatctt ttccacatag tttttagctt ttgtttggtc cgtatgcatt aaatcttgca
    43621 gattctccat ctcttggaca aattccaggc gaagtgtatt tacttcttgg atatgctgtc
    43681 gaagctgctc ataatgttgc tccaacaaat catttttgat ttttaagaaa tctacttgtc
    43741 tccgatcttt gtcggtattt aagatgtgat cgattagatt gtagctgata ataacgatta
    43801 gaatgataat atataaaatc gtagaccaat tgatcgttgt ttgatagata cctaatgccg
    43861 tttggatgta aatcaagcaa tggataatgg ctaccaagac gatccaaggt gtacaagcta
    43921 cataaaaacg gttattctta tatgcttcgc caatgcatgc aagtgaagtg actaaagtgc
    43981 ttataacact agcaatatta gcaatcggca ttaattcagg aagttctgca ggagtaaaag
    44041 ttgcataaag cagaacgccg ataaaaatca aaagttggaa cgtacaaaaa attccgtacc
    44101 attttttata gtaaaacatt cggctccaat agtagcagat gatgaaagct gacgttaaga
    44161 taataaataa atgagataaa aaagaatgaa cgaatggttc aaaaagaata ccacttaaaa
    44221 tatcttctga tacagcttca aatcctaatg ccaaagcaaa gcaacttaag agaataagtg
    44281 agtattcaag acgtttttgt ttatacatca agtagatcgt atagaaaaag gtccctatag
    44341 cgataaaaac agcgattatc atcgtcaata cttgcggcac tgattgtgaa taaataaaac
    44401 taatcaatgg tccagttgtt cctagataaa ctttcggtgg cagtccagca tagttctgat
    44461 aaggagatga gactgtaagg gtcaattttt ttccgatata atttgctggt aaatctatca
    44521 cagccaatga gagtccggga ttgctttctt cctgataatc tttccgttgg tataaaatct
    44581 tttcgcctag atatacagta atccattgat ggtttccttt gattagtaaa tttgcttcgt
    44641 ccaacggttt ttcaagtgtc gtttccataa tgaatgtttc gtctttatcc acggtaggaa
    44701 tcgtacgagt gtacttgctg tcaaacttaa aatcaggatc atcttttgta tagaaaaccc
    44761 acgaatcttt tatttctttc atttgattgc tgtccgcagg agaaaaaata aaataaaaga
    44821 aataagcaat tcctgttaaa aataacaatg ataatataat gattatgctc cactttatac
    44881 gtaaataaaa agattctttt ttattatata tgttattaaa aaaagacata aaggtattcc
    44941 tttctaaaac ttgtaatgtt agggtaaacg ttttttaaac taacgtcaat tatttataat
    45001 aaaaaatgag ataaagatga ggaaatagaa ttagaaacat ataattatta aagggaaaca
    45061 tttttacagc tataatttga aaaaatttat cgttattata tgattaagaa ggattgaata
    45121 aagaaagaag ttgaaaacga tacctgatta caaaaaaata acttttataa gttctataac
    45181 gttgattata tttttaattc ttattcttct cgtcgtcttg gttccccgaa tttttggttt
    45241 gactccttat attattgagg acaaagaaat gagtccatat tatgcacaag gaaatctgat
    45301 atatgtacga ccgaaaaata caaatgagat tttagtcgga gatattatta catattatga
    45361 aaattcagga aaaaaaatct cgacgcgtcg cgtaatagcc gttgaaaaca accacgaaga
    45421 tttttataca aaagctgata caaagactta tattgagcct ggagtagtaa aaaagagaaa
    45481 tattatcggt agtcccatct ttcagattcc atatattgga ctagtccttt caaaaacggc
    45541 atttgcatgg attcaggggt tattctttac gattgctttt tgcctaacag gaatcacagc
    45601 atggaatacc tttgtagagt tgaaaaagaa gcggagacga acacagaaat ttttgtaaga
    45661 atgttaaaaa cataaatgta ttccagagat ccaacgactc ttctgaacat gaaacacgag
    45721 aaaacactca tgcagcttgt agatttagtc agttgttcgt ataatgtgtg aagaggagga
    45781 gtagtatgcg caatgaaatg atgcatcgtc ctgtagtcaa agaagaacta ttggatttta
    45841 tgcgtaccca gcaaaaaaaa ttaccgggtg agctaggcaa actggaagaa gaagctcatg
    45901 tagcagaagt accagttatt ccccatgaaa cagttgtatt tttgaaattt ttacttggac
    45961 agcttcagcc tgaacgaatc ttggagatcg gagcagctat cggtttttca tcaagtgtca
    46021 tggccacgac aatcggagaa aacgctcatg ttacgacaat tgatcgtttc gatgtcatga
    46081 tcgagaaagc taaaaaaaac tatgaacgtc taggactgac agataaagtg actttgcttg
    46141 aaggtcaagc agcagatatc ttgccggagt tgtctggtcc gtatgacttt atttttatgg
    46201 atagtgcaaa atcaaaatat attgaatttt tacctgaatg cttacgtttg ttaagaaaag
    46261 gtggcgtttt gatggtagat gacatcttcc aaggaggaac gatcttgctc ccagatgaag
    46321 agattccccg tggcaaacga gctatccatc gtaaattaaa tgaatttctt cgtgttgtga
    46381 tggatcatcc cgatttgaca tcgacaatct tgccattagg tgatggtgtg atcttaatga
    46441 caaaggaatc agaaacaatc gagttgtgat acatgattat ggcagcctgt agataatcga
    46501 ttgaatcgag ggctcaattc gaacttgatg taaaagtttc tatatttgta agtcaattaa
    46561 aggatacagg aaatctaaat aaacaggagt agcatgaagt caatgtagct cctgttttca
    46621 attgataacc ttagaacagc tgaaggagaa tgtctcgttt taaaagattg atttagtagt
    46681 tgggccaaaa taattcatta tttgctaatt aaataactat ttcgtattga cagaagcaat
    46741 ttaattatct ataattattg atgttccgct gattcttgtc atagtagctc agctggatag
    46801 agcatccgcc ttctaagcgg acggtcgggg gttcgaatcc ctcctgtgac gctaaaaaac
    46861 cgttagaaac tgaggtttct aacggttttt ctttgttttt tgtgccaata ttgtttgttt
    46921 tcaaaggcaa ataaaataaa aaaacatcct tatcgagtac aattataagg agcaaaaaaa
    46981 taaaactcat cagaaaagag gaagaagata tgacgatact atctagaatt ttagtgactc
    47041 tagttgcaat tgaatttttt tatatcatgt atatcgaaac ggtgagaact gattctgaca
    47101 cgacaagtag ggtttttaaa atgagtaaag aagagttaag cagaaaatct gttcaaacat
    47161 tgtttaagaa ccaaggagtg tacaatggac tattaggagt gggactactt tatggagctt
    47221 atctttcttc cgcatctaaa gaaatcacaa gtatgctatt aatatctatt ttttttgttg
    47281 cattatatgg cagtttgact agcgatcgtt ggattttact caaacaaggt gggctagctc
    47341 tgttggcatt gctttctatt ttcttataaa tatagaaaaa ataagaattt atctaacagg
    47401 aaactttgtg aaaaatatta ctttatctca tgaaatatga tattctaatg aatggtattt
    47461 tagaaaattt catgaaaaag gagttagata ggtgttcaaa aattatgttt cctcactaaa
    47521 aaaagaattt tcaggttatg atctttcaag atttcagaaa gatcttttgg ctgggatcac
    47581 agtagctgct gtagcattgc ctttagcctt ggcttttggg gtatcaagcg gagctgatgc
    47641 ggccgcaggt ttgattacgg ctatcattgc cggtatcgtt attggcggtt tatcaggcgg
    47701 tttttatcaa atatcaggtc cgacaggtgc gatggcagct atcttgatgt ctattgcggc
    47761 aacaaaggga atgcaaggtg tattgcttgc tactttttta gcgggtctat ttttacttgc
    47821 agcaggactt ttccgattag gaacactgac ttcttttatc ccagcacccg taattacggg
    47881 gtttacttca ggtattgcta tcattattgc attaggtcag atcgataatt tatttggtgt
    47941 tcactcggaa ggtacaaacg ttattgaaaa actaagtagt tatcaaacga taggatttcc
    48001 gataaacaca gcctctttga tcatgggagg gctagtcatt ttagggatgt ttatctatcc
    48061 aaaaaaatgg gcgaaacgaa tgcctagttc gctgctggct atcattttgg caacagcagt
    48121 tatgctattg ttccatttac cagtagcaac tgtgggtaag attccacaaa cattgatcag
    48181 tagtaatcgt ttgaatatgg gagattttag cttttctgcc ttgcaacaag tggcagttcc
    48241 agctattagc attgctttat taggaatgat tgaaagcttg ctatgtggtg cttcggctgg
    48301 ccgaatggca aataagccct tagatagcaa tcaagaatta atggcgcaag gaattggaaa
    48361 tctgttgctt cctttctttg gcgggattcc tgctactgcg gccatcgccc gtacaagcgt
    48421 ggccatcaaa tctggtgcac aaactagatt agctggtatg atacatgcag ttgtcttact
    48481 gctctccatg cttgtttttg cgccagtgat gtcacagatt ccaatgccag cacttgcagg
    48541 tgttttgatt gtgacggctt ggcgtatgaa tgaatgggaa acgatcaagg agctatttac
    48601 taataaatat tggtcagcag ttctattgtt tatccttacg atgatttgta cagttatctt
    48661 tgatttaagt attgctatcg tgatcggggt gatcggcggc tgtgtatttt ttgttgtcaa
    48721 aagcgctgct atcacgattt cattagaaac gatcgattgg caaagaatgg ggctgccaga
    48781 aacggaaaag ctgaataact ggacagtagt gtatattagt ggtccactgt tttttatgtc
    48841 ttcagaaaaa ctcaaaaata aattggaaga actaaatcat cacgatggtg tcattttctc
    48901 catgcgaggc gtaccaagta ttgatttgac ggcacgtgca gtttttgatg aatttcaaga
    48961 aaaagcagag caaagaggac aaacgattat ctatacttcc ttgcagccag aagtagaaaa
    49021 acaactttct cacttgtggg aacatacatt cacgcatcaa catcaaacag ttgctcatgc
    49081 gttgacagct ttacatgcga aatatactgc aattagccat taaaacaatg aaaaagaaca
    49141 gacaagactg taaactgaag attttatggt cttgtctgtt ctttttaata ttgctgtaaa
    49201 agtgaagcta gtacttgcca gtcttgatgg ataacaggta caagggagcg attgtagaaa
    49261 atagctgctg gatgaaaaag tggaagaatt cgatagtttt tttctgacca ttcgtaggca
    49321 tccttttgtt ctgttaattg taagacaggc cctgtataga gttgaccatg atttttggta
    49381 accgtatatt ctttgccaag taaacgttga agaccaatgt ttccaagtgt cgcaattaat
    49441 tttggctgga ccttcatcag ttcgtaatcc aatattggtg catgcgcaaa tacttcggaa
    49501 cgagtaggtg tccgatttgg ataaacagtt tctgactgtt gtgtccgttt attgatccga
    49561 tgagtcacgc gatacgggcg gctccttaca gcactggtga tatacacctc ttctcgtgtt
    49621 aagccagttg aagaaagtgc ctgcatcaat tcttttccag cttgaccgct aaaaggaaca
    49681 tgcgtatcaa tctctgtttt ccctggggct tctcccacga gcatcagttt aggatgaaga
    49741 ggtccttgcc cagcgataaa tccttctaca ggacggccgt tcattcttaa agaagcttct
    49801 tgtatcagtt cttttgggta ttccatttat gctcctcctt tttcttttat tataagaata
    49861 aaagaaacac aatgcgacta ttttatttgg tagaactgtg aggatagaaa agcagaagta
    49921 ttgcttgaat ttttgtttta ctttttgatt ttaaatttag ttgactaacg gttgctgttc
    49981 tggtaagcta gtactgttgt aattgtggac tccacagcta caaccgctca gaacaagtaa
    50041 taagcacagc atatgctgtc acttcggatg gcgagtctaa gtatatcaga aggaggtgct
    50101 ttatagcatg tacgcaatta ttaaaactgg tggtaaacaa gtaaaagttg aagtgggaca
    50161 agcaatctat gttgaaaaac ttgacgttga agcaggagaa aaagttgttt ttgacgaagt
    50221 tatcttagta ggcggagaat ctacaaaagt aggcgctcca actgttgcag gtgcaactgt
    50281 tgaaggtact gttgaaaaac acggcaaaca aaagaaagtc gttactttca aatacaaacc
    50341 taaaaaacat tcacaccgta aacaaggtca tcgtcaacca tatacaaaag tggttatcga
    50401 cgcgatcaac gcttaatagc gtttgagaaa gaaggcctat atatgatcaa aggaacattt
    50461 aagcgaaatg acgcaggtca gatcgtttca ttcactttga ccgggcatgc tgatgctggt
    50521 ccttatggaa gtgatatcgt ttgtgcgggt gtttctgcgt tagcgatcag cactgtcaac
    50581 gggattgcct cattagccgg ttttgagccg attgttgaaa tgaatgaaga agaaggcggt
    50641 tatctttata ccgaagtcac ttcaggaatg acacaagaac aaaacaatat tgctgagatt
    50701 ctattagaaa atcttttatt aggattacaa tcgatagaag ctgaaaactc agaatatatc
    50761 caaattaaaa caattaatga taaataggag gtgcagacca tgttgttatc tatgaatcta
    50821 caattatttg cccacaaaaa aggtggcggt tctacatcta acggccgtga ctcagaatca
    50881 aaacgtctag gtgctaaacg tgctgatgga caaacagtta caggtggatc aattctttac
    50941 cgtcaacgcg gtacaaaaat ctatccaggt gtaaacgtgg gtatcggtgg agacgacact
    51001 ttatttgcaa aagttgatgg cgtagtacgt ttcgaacgta aaggccgtaa caaaaaacaa
    51061 gtgtctgttt atccagtagc tcaagaagct taattgaatc ttatgattaa agaggttgtg
    51121 acaagacttt tgtcacagcc ttttttgttt ataaaaataa aagttgtagt ggaggctacg
    51181 aagtttactt tgtcttttta cacttaatat ttttttgcca atttggaatc aggatgtttt
    51241 gataactatc gttttcaatt gatggaagct atattgtttg ctatcagtga aataattata
    51301 tggtaaacag tgttcttttt cttgtttcca ttataaaaat cgtatcggga tttttcgttc
    51361 ttttaaattg aacatttcta tctatccgcg tgttatcaac aaaacaaaat caggtaaata
    51421 gttgacgaaa cagaaataaa tacatagtat tatgttttga agcctaagta caatagtcta
    51481 tagaaaagga gcgataccat tggcaaaacg cattgaccga atttatatgt atgtcaaaga
    51541 aaaaaccgct catttaacaa aggcagaata tgatcaagga gtaacaacac aggaaattgc
    51601 tgaagtgtta gggattcagc gaacaaatag cagtaaagat ctgaatcagc tagtgcgcga
    51661 aggaaaactg ataaagacag acggacgacc agtacgttac atatatcaaa cactcgttac
    51721 gcacgtaaag ccagttacaa aacatgtagt cagttacaaa gaaacgccgg tctctgaaga
    51781 aaaaaataca ctccaaatag atactaagga tatctttgca aaaatcattg gagctaacgg
    51841 cagcatgaaa aattcagtgg aacaggcaaa agctgcgatt ttgtatccgc caagaggatt
    51901 aaattgtttg attacaggac ctaccggatc aggaaagact tattttgcac acgcgatgta
    51961 tcattttgca aaagcgcatc atgtaataga tgaggaaacg gaactgattg ttttcaattg
    52021 tgctgattat gccaataacc ctgagctttt gatgagtcat ttatttgggt acgcaaaagg
    52081 tgcttttaca ggcgcagatg aagaaaaaat ggggattatc gatcaagcgg atggcggtat
    52141 gctgtttttg gatgagattc accggttgcc gcctgaaggt caagaaatga tcttttactt
    52201 tatggatcat ggaacttaca gtcgtcttgg ggaaacaacg aaatcccatg aagcaaatgt
    52261 acggatcgta ggtgcgacca cagaagaccc aggttcttct ctattagaaa cttttgttcg
    52321 gcgtatccca atcaatatca aacttccggc ttttgaaaaa cgtcctgcaa atgagaaagt
    52381 cgatttagta aaaatcatga ttgcccacga agcaaaccgc acgcagcgaa agatttcttt
    52441 gacagaagat gtagcaaaag cattgatcgg cagtgtgacc tatggaaata taggacaatt
    52501 gaagtcaaat atccagttag tatgtgcacg aggatttcta aatcatatgc aatcacccga
    52561 aatctcgatc acaatcgatg atttgacaga agggattcgt agcggattga ttcaattagc
    52621 aagcaaccgc agtgcaatgg cagagctttc taaaatattg gagccaaaga taactgtagc
    52681 accaaatgat acgatcatga aaatccaatc ggactcctat gagttacctt ataatctata
    52741 tgatatcatc ggagataaag cagctttact gaagtcggat ggtttggatc aagaagcaat
    52801 caatcatttc atttctacag atatcaacat ccatctgaag tctttctata aagaccatgg
    52861 tttttctttt aatgcagaca gcaaattagc agaatttgta gatccgaaaa tcatagaagt
    52921 gaccaatcag atttatgtaa tggtcaaaag atctttacca tatgagtttc agcaaaactt
    52981 tatttatgct atgagcttgc atatcagttc ttttttgaaa aaaatcaact taggagaaga
    53041 acggcatacg aatgataaca tccgtgagat ggcttttgat tttccagatg aatatgctgt
    53101 tgcgaaagaa gtgcgtagtt atatcgaaac gtattttcaa gtggagattc cagaaagtga
    53161 agactattac ttgaccgttc tactcgtctc gttacgggca aatcaagcaa gcggcagaat
    53221 cggtgtagtc gttgcagctc acggaaacag cacagcaagc agtatggtcc aagttgtcca
    53281 acagttgtta gatgcagaga acgtacgagc agtagacatg cctttggata tggatccgaa
    53341 aacagcattg gaccgaattg aacgcaatgt acaagaagta gatgaaggaa gcggggtcat
    53401 actcttagta gatatggggt cccttgcgtc gtttaattcg caaattcaaa gagacactgg
    53461 aattccagta cgtactgttg atatggtaac aacttctcta gttttggaaa ctgtacgaaa
    53521 ggtctcagta ttagggacag atctagatat gttgcatgaa tcattgaaaa attttcgagg
    53581 ttacgcagaa atatcttctg tagaatctgt tcaggaagca aaacctattc ataagaaaaa
    53641 agctgttttg gctatctgcg catctggcga aggtacagca caaagaatca aagaattgat
    53701 cgaacgagcg gtaaacaagc gtcaagaaac agaattagaa gttctagctt tgtcgattgt
    53761 ggaagtgaaa gaagaactgc cagttatcca aaaagaatat cagatcatag ctactactgg
    53821 gattactgat ttgaatatcc aagccccatt tattccttta gaacgtttta ttgatcaaaa
    53881 tatcgaagtc attttggatc agttgctgat ggaatcagaa ttggaggaaa ctgaattcat
    53941 ctccctagat gaagagtcag ctaaaaatac gtgtgttgag tttatctctg ataacttcat
    54001 ctttattaat ggtagtaagt taatcgatcc aatgtggcaa ttttctacac aaatctctca
    54061 gacgacggga atcggcgatg aagaatatgg attcaaaatc aacctagtga tgcacacagc
    54121 aggaatgatc gaacgtatta ttcggaatga accattgact gtggaagaaa acgaattgac
    54181 aaatacaacg aatgatcctc tttatagcca attggcagcc tcagttgttc tgttggaaga
    54241 tcagataaaa gtaaaagtgc cgatagaaga aatgtattat ctgctacgtc tagtccataa
    54301 tcagttagat aaaaaagaat acactgtgcc atgaatacac aaaaacgata cacttttata
    54361 gtgtatcgtt tttgtgtatt ggttaagaat cctttaaatt caattagtgt atcgtaaaaa
    54421 agttggcacg ctttttgctt atagtagtgt gtgctaggag gtggttgttc acacagaaat
    54481 gataggggtt tctgtgaagt agtgaggaag aaggagtttt gcagatggat attcgattgg
    54541 cacgtataga tgatcgttta atccacgggc aagtcgcaac agtttggtcg aagcaaacag
    54601 gtgttgaacg tatcattgtg atcagcgatg tagtcgctca agataaattg agaaagtttc
    54661 tactaaaaga agctgcaccg ccggggatca cagcaaatgt aataaccgtg cagaaaatga
    54721 ttcaaatcta tcatagtgga ttattatcac gagcaaaagt gatgctttta ttcaccaatc
    54781 cccaagatgt tgaagcggtt gtccgctgcg gtgtacagtt gaagtcgttg aatatcggcg
    54841 gtatgagttt tactgaaggc aaatcaatga ttaccaattt tgtttcagta aatcaacaag
    54901 atattgattc ctttcgttac ttgaacagtc aagaagtgga gttagagatt cgaaaagtac
    54961 ctgctgacag gaaaatcctt ttgatggaac tactagcgaa aatcaaaaag gtgtagcaag
    55021 aatggttgtt ggaaaaggtc aaataattct gttgtaatgg ttagcaatta ttaatatttt
    55081 tgaatttgtt acaacaaaag taaataggag gtataaatat ggtagggatt atcctagcaa
    55141 gtcatggaca atttgctgaa ggaatcttac aatccggttc aatgatcttt ggcgaacaag
    55201 aaaacgtcaa agccgtgatt ttgaaaccaa gtgaaggtcc agatgacttg agagccaaat
    55261 tggaagaagc ggttgcttct tttgataatc aagacgaagt gttattctta gttgatttat
    55321 ggggcggaac accgttcaat caatcaaaca cattattcga agagcacaaa gataaatggg
    55381 caatcgtcag cggtttgaat ttaccaatgt tgattgaagc ctacgcatca cgcttttcaa
    55441 tggaatctgc tcatgaaatt gcagcacaca tcattgaaac agcaaaagac ggtgtaaaag
    55501 taaaaccgga agaattagaa ccggcagaag caccgaaagc agcagttgaa gacgcacaac
    55561 ctaaaggagc acttccagaa ggaactgtgg tcggagacgg aaaaatcaaa tatgtattag
    55621 cacgtgttga ctcacgtctg ttacatggac aagttgcgac agcttggaca aaagcagtgc
    55681 aaccaaaccg tattatcgtt gtttcagatg cagtatcaaa ggatgatctg cgtaagagac
    55741 taatcgaaca agctgctcct ccaggtgtaa aagcaaatgt tattcctatt agcaaaatga
    55801 tcgaagtagc aaaagaccct cgttttggaa ataccaaagc attgctttta tttgaaaatc
    55861 ctgaagacgt attgacagct gttgaaggtg gcgtagacat caaagaatta aatgttgggt
    55921 caatggcgca ttcggtcggt aaagtcgttg taagtaaagt attgtctatg ggacaagaag
    55981 acgttgaagc gtttgagaag cttgaacaaa aaggtgtgaa attcgatgta cgtaaagtac
    56041 ctaatgattc acgcgataac atggatgata ttttgaaaaa agcaaaagct gaattagcaa
    56101 aagcgtaata aataatatta aaatttatag gaggcttatc atgtctatta tttcaataat
    56161 tttagtcgta ttagttgcct ttctagctgg tatggaaggt attcttgatg aatttcaatt
    56221 tcatcaacca ctagtggcat gtacattgat cggtttagtt accggtaacc tcgaagctgg
    56281 tatcgtactt ggcggtacgc ttcagatgat cgctttaggt tgggcaaata tcggtgccgc
    56341 tgtagcacca gatgctgcat tagcatcagt agcatcagca attattttag ttttaggtgg
    56401 acaaggtgtt aaaggtgttc cttctgcgat cgcgattgcc gttcctttgg ctgttgcagg
    56461 gttgttctta acaatgatcg tacgtacaat cgctgttcca atcgttcatt tgatggatgc
    56521 ggctgctgaa gaaggaaaca tccgtaaggt tgaaatgtgg cacatcattg ctgtatgttt
    56581 acaaggggtt cgtatcgcgg tcccagcagc agcgttgcta tttatcccag cacaaactgt
    56641 gcaatcattc cttgaatcaa tgccagcatg gttaacagat ggtatggcta tcggtggggg
    56701 aatggtcgta gctgtaggtt acgctttggt aatcaacatg atggctacaa aagaagtatg
    56761 gccattcttc gttattggtt tcgttgtagc tgcaatttct caattaacat tgattgctct
    56821 aggtgcttta ggtgttgcat tagctcttat ttacttgaac ctttctaaaa tgggtggttc
    56881 atcaaataat ggaggcggaa gcaactctgg tgacccttta ggcgacattt tgaatgacta
    56941 ttaatcttga aggaggaaaa taaaatggca gaagaaaaaa tcaaattatc aaaaaaagat
    57001 cgtttagctg ttgcgtggcg ctctaccttc attcaaggtt catggaacta cgaacgtatg
    57061 caaaacggtg gctgggcatt ttctatgatt ccagcaatca aaaaattata caaaacaaaa
    57121 gaagaacgtt ctgcagcatt aaaacgtcac ttggaattct ttaatacaca cccatacatt
    57181 gcttctccaa ttttaggggt tacattggct ctggaagaag aacgtgcgaa tggcgcgcct
    57241 gttgatgatg tagcgattca aggggttaaa gtaggtatga tgggtccttt agctggtgtt
    57301 ggtgacccag tgttctggtt tacagtacgt ccaatgctag gtgcactagg tgcttcatta
    57361 gctatgggag gaaatatcct tggaccaatc atcttcttct taggttggaa cattattcgt
    57421 tgggcattca tgtggtatac acaagaattt ggctacaaag ctggttctaa aattactgat
    57481 gacctttctg gcggattgtt acaagacgta acaaaaggtg cttcaatttt agggatgttc
    57541 gtattagctg cccttgtaca aagatgggta tcaatcaaat tcttaccagt tgtatcaact
    57601 gtaaaattag ataaaggtgc ttacatcgaa tgggataaat tgccttcagg tggtgaagga
    57661 atcaagagtg catttgaaca agttaataat ggcttagccc tttctcctga aaaggtaaca
    57721 acattacaag acaacttaga ccaattgatt cctggtttag ctgcattagg attaacattg
    57781 ttatgtatgt ggttgcttaa gaaaaaggtt tctccaatcg ttatcatcct tggtttattc
    57841 gtagtcggtg ttgttggaca cgtcatcgga cttttataat ccataaaaat atagctcggg
    57901 cgttgtcccg agcttttttt atatagtata ctgttcataa acaaatatct ggagggagaa
    57961 aatggttcaa tcaatcaata caaaagtaga cttggtaatt gatgctactt cgtttacggg
    58021 tctgacagat tacgggcaaa tcatgatagg taataatggt tttgagtttt accatgcgcg
    58081 agatagacgc aaatatatcc aaattccatg ggaagaagtg gattatgtac tagcatcagt
    58141 catgctaaag ggaaaatgga ttcctcgata tgccattcaa acgaaaaaaa atggtacata
    58201 cacattttct tccaaagaac ctaaaaaagt gcttcgtgcg atcagagaat atgtagatga
    58261 agatagaatg gtacaatcat tgagtttctt tgatgtagtg aaacgtggta ttcgtagtat
    58321 gtttaaacgc aagtaaaaaa taaagaaaac ttctaagagg aggttttctt tattttttta
    58381 ctttgcagaa gaaaatatga aatagcaaaa ccaattattt gtccccttta aatcccatat
    58441 gctaaaattg attagcaaag aaggaggtta tattatgagt tggttatgga cattgattgt
    58501 tggagccgtg atcggagcaa ttgcaggtgc gatcaccagt aaaggaaatt cgatgggctg
    58561 tgtaacgaat atcattgctg gactagtcgg ttcaagtatt ggacaagcga ttttcggcga
    58621 atggggacca aaagctgcag gtatggcact tattccatct attttaggcg cagtgatttt
    58681 ggtagcagtt gtctcatttt tctttggaaa acgatcataa gtttttacaa aatagtaaac
    58741 taaaaggagt tgcagcgaga ctgtgactcc tttttggctt tatttattta aaataaaaag
    58801 aagttttccg gaaattttta tttaactgtc gtgtacgaag aaaagtttgc tataatggaa
    58861 aaaagcgtgc aaagaaagag ggagtttcat tatgatgcta cgtgtagaaa aattgcgcaa
    58921 aaaaatgcaa gaagaaaatt tggattcatt tttggttacc agtccgtaca atcttcgtta
    58981 cttaacgaac tttacaggta cgacaggatt agctgttatt actttggaaa aagcattttt
    59041 tattactgat tttcgttata ccgagcaggc ggcagcgcag gctcaagggt ttgaaattat
    59101 taaaaatgtc ggacctattt ttgatgaggt agcaaactta gtacgcaaag aagaactgca
    59161 ctcattagct tttgaggaaa caacagtctc atttttagaa tattcggttt tagaagaaat
    59221 catcgatgcg gaattagtac ctgtttcaca gatgatcgaa gaactcagag aagtgaaaga
    59281 tgaagaagaa atcgctatta tcgaaaaagc atgtcatatt gcggatatgg catatgatca
    59341 catcctgaaa atgatccaac cgggcatgac tgagattgaa gtcgcaaatc aactagactt
    59401 ttatatgcgt tctcttggcg cttcaggtgt ttcttttgat acgatcgttg ctagcggatt
    59461 gcgttcggct atgccgcatg gtgtagcaag caaaaaaatc atcgaacaag gtgacttgat
    59521 cacattggac tttggttgct attacgaagg gtacgtttcc gatatgacac gtacattcgc
    59581 tattggtgat cctggggaaa aattaaaaga aatttatcaa atagtcttag atgctcaatt
    59641 agcagttatt gatgctgcaa aaccaggaat gactggtgtc caattagatg cagttgctag
    59701 agattatatt tcaaaacatg gttacgggga agcatttgga cattctacag gacatgggat
    59761 cggtttagag atccacgaag gaccaaacgt ttcttctcgt gcagaaaagc aatttgtacc
    59821 aggaaatgtg atcactgatg aaccagggat ctacttacca ggaatcggtg gagtacgtat
    59881 tgaggatgac ttgttgatca cagaagatgg aaatcgtgtg ttgactcgtt caccaaaaga
    59941 attgatcatc ttatagtttc atcaatagaa gaagtaagcg taaaaatcag tgttcacaga
    60001 ctttgttata gaaaatcact cgatttaatg atacactata gaagaacttt taagctgtaa
    60061 gagataataa agttgggtgt tttctccaat tcatagcagt ttgcagctga tcggcggcag
    60121 ttttcttacc acgtgatcac tatgccgcat catagagaat tcggatgtat ctcgtgctta
    60181 ggcaaaggga ggaataaata aatggcagat gaaaaaaatt tgattttaaa cgcaaaccaa
    60241 gatttaggag agatcgtgat cgctcctgaa gtcatcgaag taattatcgg gattgcagct
    60301 tctaaagtag aaggcgtata cggaatgcgc ggaacttttg ccagcaatgt cactgaatta
    60361 ttaggacgtg cagctcacgg aaaaggtgtt tacttagcaa acgaggaaga tggcttgaaa
    60421 gtagatcttt actgttatct agaatatggt gtttcagttc ctaaagtagc aatggaaatg
    60481 caggaacggg tcagccagca agtccttttc atgacggata tcgatttatc tgaagtcaat
    60541 atccatgtag tagctgttgt tcctgaaaaa ttagaacaac caacaatcga agaacttttt
    60601 gaagacgaag aggaagagaa tgaataaaga attatcaaga cacgagattc gggaaatggc
    60661 attgcaggct ttatttccat tagacttcaa tgcagaccta acaaaagaag atgcgatttt
    60721 caacgcaatc gaattagacc accgcgacat gatcaacgaa gatgaatcag agtttgttcc
    60781 tgtttatctt gatacgctag ttggcggtgt ctgtgcaaaa aaagatgaat tggataaagt
    60841 gattgaaaaa catttaaaaa acaattggca catcaatcgg atctcaaaaa tggatttggt
    60901 gatcttgcgt atcgcgattt ttgaaatgac ttatgtgaca gatgtaccag cggctgttgc
    60961 tttaaatgaa gcaatcgagt tggcaaaaac atttagtgat gaccgttcac gtaaattcgt
    61021 caacggtgtt ttatccaatg tattgaaaga attagaagct ggggcgtaag tcctagcttt
    61081 tttctatgaa tcatcataaa cctgttataa atcgggaaaa ttctatggta gaatgaaaac
    61141 acaaaaaata tctgggagtg gttagatggc agaattgatt aacggaaaag aattagctga
    61201 aaaaatgcag gcagagattg ctgaaaaaat ccaaaaattg aaagataatg gtatccatcc
    61261 cggattagtc gttttattgg taggggaaaa tccagccagc caaatctatg taagaaataa
    61321 agaacgtgta gcaaaagaaa tcggaatcca ttcattggta gagcgttatc ctgagacgat
    61381 ttctgaagac gaactacttg cagaaattga aaaatacaat caagatccta gttttcatgg
    61441 tatattggtc caattaccat tgccaaagca tatagatgaa gaaaagatcc tgttagctat
    61501 ccgccctgaa aaagacgtag acggttttca tccgatgaat ttaggcagac tccttgcggg
    61561 taaaccggac aagattcctt gtactccata cggcatcatg aaaatgtttg aagcttattc
    61621 tatcgatccg gcgggtaaac gagcagtagt tatcggacga agcaatatcg tcggtaaacc
    61681 gatggctcag ctactcttga tggcagatgc aactgttact gttgctcatt ctaaaaccga
    61741 aaatctggct gaactggcac aagaagcaga tattttagtc gtagcaatag gacgtggaca
    61801 ttttgtcaca aaagaattcg taaaaccagg tgctgtagtg atagatgtag ggatgaatcg
    61861 tgatgctaac ggtaagctga tcggtgatgt gaaatttgat gaagtggagc ctattgcagg
    61921 ctggatcact cctgtgccaa agggtgtagg gccaatgact atcacgatgc tgatgtatca
    61981 aaccgtaaaa tctgccgaag cttttggagc aggtgaatag atggcacaag aatatttaac
    62041 tgtcactaca ttaacgaagt atttgaaaag aaaatttgat gccgatcctt atttagaacg
    62101 cgtatattta acaggcgaaa tatcgaattt ccgtttacgt gccaatgccc atcaatattt
    62161 cagcttaaaa gatgaccatg caaaaatatc tgctattatg ttcaaaggag cattccaaaa
    62221 attacgattc cagccaaaag aaggaatgaa agtccttgtc gttgggcgta tttcattata
    62281 tgaagcggga ggttcttatc aaatctatgt agagcacatg gagcctgatg gaataggtgc
    62341 tttatatcaa gaattggaag aacgaaaaga aaagctgatg aaggaaggcc tttttcaagg
    62401 gcctaaaaaa atgctgccac gtttcccaaa gcgaatcgcg gtccttacca gtccaagcgg
    62461 agcggttatc cgcgatatca tcacgacggt gaaaagaaga tatccaattg tccaattggt
    62521 tttgttccca acagttgtac aaggaaacca agcagcggac aatgttgtca ggaatatcca
    62581 gagagtagaa gagatgggca atttcgatac aatgatcatc ggtcgtgggg gtggttcgat
    62641 tgaggattta tggccgttta atgaagagcg ggttgctcgg gcgatttatc aagctaatac
    62701 gccggtgatt tcatctgtag gacatgaaac agataccacg atcgctgatt tagtagcaga
    62761 tgttcgggct gccactccaa cagcagctgc agaattagct gttcctgttt tgtcagaaga
    62821 gttgatgcgc attcaagaac ggcaagctag attgcagcag gcgtttgtac gccagatcca
    62881 gcgcaaacaa gaacggttcg agcgtgctcg acgttcctat gtatttcggc agcctgaaag
    62941 attgtatgaa ggtcagacca tcaaattaga ccagttgaaa cagcgattat atcaagctac
    63001 acagcaaatt tatcatgcga aagaaaaaca aacgatcgca ttaagccacc aattggaaca
    63061 agtggctccg ctttatcgag ttaaagcagc tcgccaagaa actgcttatc tagaaaaacg
    63121 cttagaagag aaaatccaac aatatatgaa acaacagcag cagcgttttg ctcaagctgt
    63181 tcaatctctt gatttgttga gtccattgaa aatcatggga agaggctaca gctatacgac
    63241 gttaaatgat caagtagtaa aaagtgtcac cgagattcat caaggggatt tgctgacgat
    63301 ccattatcaa gatggaatcg ttaaaggaca agtacaagag atagacaaag gagaataaaa
    63361 atatggaaaa tccaactttt gaagagtcac tgcaagaatt agaaaaaatt gtcatgcagt
    63421 tagaacaagg agacgttcca ttagaatcag ctctagattc gtttaaacga ggaatggaat
    63481 taagcaaaca ttgccaagat acattagcta aagcagaaga gaccttgacg aaaatgatga
    63541 cagaatcaaa tgaagaagtt gattttgacg gaaacgagga aagctgagat gagattaact
    63601 gacttttcag ctattcatct acctgctgta gaaaaagaaa tcttgtcttt tttagatgag
    63661 catacaacgg atagaggact ctatgatgcg atgagttatt cagtgaaagc aggcgggaaa
    63721 agaatacgtc ccttattact tttaacggcc gttgcttcct ttgatgagcc tattgatgtt
    63781 cccgtctatc aagtagcagc tgctttagaa atggtgcata cgtattcctt gatccacgat
    63841 gatttgcctg cgatggacaa tgatgatctt cgtagaggaa aacctaccaa tcataaagta
    63901 ttcggcgaag cattagctat attggccgga gatggtttgc ttacaggagc attccagcta
    63961 atcagtatgg cacacttagg taattctcct aagcttctgc tgcttcagca attagctgtt
    64021 tgtgcgggat cacaaggtat ggttgctggg caagctgcag atatcgaggg cgaatcgaaa
    64081 aagctttctt tagaagaatt agcatttatt catgaaagaa agacagggca tttgattcgt
    64141 tatgccttgc tggctggtgg catattagcg aagcaacctg aagaaatctt attgctactt
    64201 caacgattag ccgaacattt aggtttagct tttcagataa gagatgatct actcgatgtg
    64261 attggtacaa cgaaaacatt agggaaaaca gctggtaaag atgaacgtat ggaaaaaaat
    64321 acttacccgc gtttattagg cctagaaaag acacgtgagg cgttggagat tgagctgtta
    64381 tccgccaaca agatcataga caaattagaa gaggacgttt tttcttttga tggcgggctg
    64441 atgcgccaga tgatcaagca atttgatgtg gagaaatgag ggaaagaatg gaaaaagaac
    64501 gcgtagatgt attagcggtc aaacaaggat tatttgaaac aagagaacaa gccaaacgtt
    64561 cagtgatggc tggtttgatt tacaacgaaa aaaacgagcg gtttgataaa ccgggagaaa
    64621 aaattccagt gagtagtgaa ttaagagtca aaggtaaaaa acttccttat gtttctcgag
    64681 ggggattaaa attagaaaaa gcactcaaag catttgatct atctgttgaa ggaaaaacat
    64741 tgttagatat tggtgcatcc actggcggat ttactgatgc agctttgcaa aatggcgcaa
    64801 aaatgagtta tgctttagac gttggctaca atcagctagc ttggaaaata agacaagatc
    64861 ctagagtcgt cgtaatggaa agagtgaatt ttcgttatgc aaaacccgaa gactttacct
    64921 taggaattcc agaagttgct gttatcgatg tttcttttat ttcactaaaa ctgatgctgc
    64981 ctccattaca tgctatttta aaagaagagg gagaagtgat tgctttaatc aaaccccaat
    65041 tcgaagcagg cagagaagct gtagggaaaa acggaattgt tcgtgaccct cagacccatc
    65101 aaaaagtttt agaagacatt ttgtcatttg cggcacaagg tggatatgat gtgctggaat
    65161 taagttattc tccgatcacg gggggagaag gaaatatcga gttcttggct cacttgagga
    65221 aagtacccga aagcggaaca atcaattcag ctattaatat ggcagaagtg gtttcaaatg
    65281 cacacgaaca gtttgaccat aaataaattg taactgtgaa aatcaagtga gaagtatgcg
    65341 gattcttctt tattatacca aggaaataag ctatcattga ttaagaagaa tatgctaagg
    65401 agcgaagacg taatgagaaa aaaagatcgg catcgtttga ttactcgatt gttgagtgag
    65461 caagatatcc gaaagcagga agaatttgtt gaaatcctga aaagcaaagg aatatctgtt
    65521 actcaagcta cgatttccag agatataaag gaactgaaac tgatcaaggt accggcttca
    65581 gatggcggct accgttatag cataccagct gaaacaaacg aagatgtaaa tactaaattg
    65641 gaaaaactat taaaagacgc tttcgtggca gttgaccaaa tggaaaaatt tgttattttg
    65701 aaaacattgc cgggaaatgc ttcggcagca gcaaatttga ttgataaacg ttacaagaaa
    65761 gaattatttt cgattatcaa tgatgacgat aatgttttga tgattacacg aactgaagac
    65821 caggcagttt tattgaagaa agacttcctg cattaccttt aagttgagga gcgaatgtga
    65881 tgctacaaga aatcagtatt actaactttg cgattattcc ggaattgcgg ctttcttttc
    65941 acgaaggaat gaccgcgctg accggagaga ctggtgcggg taaatccatt attatcgatg
    66001 ctttaggtct gttagcagga ggaagaggtt caagcgatta tatacgtcaa ggagcagaaa
    66061 aatgtgtgct tgaagggttg tttgaactac caaaacaaga aggattctct gaactgatgg
    66121 ttgaattagg gatcgaaaca gatgaggaca atctgattgt tcgacgggat atgtccttaa
    66181 ctggaaaaaa tgtttgtcga gtgaatggtc atattatcac attagctaat ctgagaagaa
    66241 tcggcagtta tttagtagat atccaaggac aaaacgaaca tcaggaactg ctccagcctg
    66301 aatcacatct tgctttattg gatcgttttg gagatgtagc tttccaacag aagaaaaaga
    66361 gttatcagca agaatatatc tcttatcgtg agctggaaaa aagggtacga aaagtgcagc
    66421 aaaatgaaaa atcctatgtt cagagaatag atatgctcca tttccagcaa gaagaaatag
    66481 ctgctgctga tttgcaagtc ggagaagaag agaaattaaa agaagaaaga gaaaaactta
    66541 gcaattatca aaaaattgct gatggattag ctgcaggtta cggagcactg acgaataatg
    66601 aacaaaacag tgtagatggt gttggcttgg ccgtttcaga actgcaaggg atcgcccatc
    66661 tagatgtgga gtatgaagca atttatgaaa atatccaaag tgcttactat ttgctgcaag
    66721 atgcaatcgg cgatatgagt cgtcagattg atttattgga gttagatgag agtcgtttag
    66781 aagaagttac gcaacgttta gaattaatcc gacagttgaa acgtaaatac ggcgaatcca
    66841 ttgagtcaat attggcttac tatgacgaaa tcaccgaaga gctagcttct tctgattttt
    66901 cagaaggtca attggacaaa atgaaagagg aactagagca aaaagagctt ctacttcagc
    66961 aacaagccgc agatcttcat gaagcgcgta aaaaaatcgc aaaagaattg gaaaaatcca
    67021 ttctgcatga attgaaaagt ctgtatatgg aaaacactga gtttgaggta cgtttcttaa
    67081 aagaagaaaa tagacaattg aatcatgatg gatttgacca aatcgaattt tacattacga
    67141 ccaatccagg agagccactg aagcctttgg tgaaagtcgc ttctggtggc gaactgtctc
    67201 ggatgttgct tgctttgaaa actatttttt cttctgagca aggtgtgaca agtattattt
    67261 ttgatgaagt ggatacaggt gtgagcggaa gagttgcaca ggccatcgca gataaaattt
    67321 ctcaaatatc gaaatactct caagttttgt gcatcactca tctgcctcaa gttgctgcag
    67381 tcgccgacta tcaatattat attgtgaaag cagtgattga tggacgtacg caaacttctg
    67441 tttcagagtt gaaaacaaaa gaaagagaag aagaaattgc acgtatgctg gctggaagtg
    67501 agattacaaa actcacactc gaacatgcaa aagaactatt gaaactcgca aaaaggacct
    67561 gagccacctc gcagtggttc aggtcctttt cagcagctga tagctatatt ttatttttac
    67621 atgacactca ttacagcagt caatacaaca gatccaatcg ttaaaatcag cattgtccaa
    67681 atgacaaatt ttgttacttt agcaaaagta cttgtttgtt ttttttcacg cattgttttc
    67741 aacctcgtca ttaattagtt gattcaagtg tacaatcttt tttccatttc cacaagaggg
    67801 cttttttata aaaacttccc tttttttaaa taataggtag ttacgataca aataaataat
    67861 gttaatagaa ctagccatat aaaggcatca tccctttcag caataggtaa cttaatgttc
    67921 attccataga tactgccgac gattgtcggt atagttaaaa taatcgttaa agaagttaaa
    67981 attttcataa tattattcag attattcgat acgattgctg aaaaagtctg attcatttgt
    68041 tctactagtt ttaattgaat gcgagaagta gtcattgcct gctctgtttc caccaataca
    68101 tcacgtaaat gatttttcaa agcatgattt tcttggaaaa gtttattttg cgctagttct
    68161 ttcaatgcat ctaaattagc agaagtcgct tctctgaaat aaacgaggct tttttggata
    68221 tccatgattt gataaagttg tttgttttca gtggatactt gaagtttggc ttccaaagta
    68281 tcgcattgag attgaagcgt agctaaataa ctgttgtaag agagtgtgac ctgccaaatg
    68341 aattgaaaga agatattgag attaggcgaa atatcacttt ttggaaaggt ctggctaaag
    68401 actttcttta aaaacagtgg ttcatgattc gtaattgtga taagcttctt tttgggcgtc
    68461 aaaataatag agagcgggta tgtatccact tgaaaataac cgctaggact tgttttagca
    68521 aaaggatatt gtaacaataa taacgctggc tttgtcaact ttgattgatt gaattcttct
    68581 gtacgggaat tttctgcatc gtccaatatg gaagtgatgt aatctgacgg aatttcaaat
    68641 tgatgtgtca gctgatgaat ctcttcttga ttaggacgtt ctacacaata ccagatcgtt
    68701 tggtcagttt cctttccggt attacgcagt ttctcattat ctaatgtaaa atatttgatc
    68761 atgattttcc tcctgttgcc tgtttctttt attataacgg atagggaatt ggaatacatg
    68821 gaatgtgttt gtaagatata gaatataact gcataaattt aaataaaatg aaacagttgt
    68881 gtaaagtata tacagtatac ttgaagcaac gataaaaaag gagtttacgt tcatgggcac
    68941 attcacacca cttatcttgt tttggtatat ttacccggta atcgttttgt ttggttgcca
    69001 atttcttgta aaattatttt cgttaaatcg tcgttttaaa ataaaagccc ctgatttggc
    69061 gattcctttt ttgtggggcg gtatgcatgc attgtctaga aatacaggga caatttctat
    69121 cttaccgttt ttctttattt ctgttttgct aatgggaatt tgtattgctg ttttccaagc
    69181 atattattat gaagaaatta tttatccgcg ttatttcaag atgacttggc gtttggtttt
    69241 tctgttgaca atcgtcttgt acgctgtctt gatcattgtg aacatacttt cttacctatg
    69301 aaaaaaatag aaaagctgta aaaagtcttt taaaaggctt tttgcagctt gatttttaaa
    69361 aaaatgttta tgaataaaaa aagttgttcc cggatttccc agaaaaggtg gtagaaagtg
    69421 ggggattgtg gtagactaat tttagttagt ggaggaatgg ggggctttca atgttgatgg
    69481 gtgaattcca acataatatt gatgcaaaag gacgtttaat cgtgccctca aaacttcgtg
    69541 aagaacttgg cgaaaagttt gttctgacac gcggattgga tggctgtctt ttcggctatc
    69601 cgatgagcga atgggaaaat ctggaagcta aactgaacga aatgccgttg gctaaaaaag
    69661 acgcacgtac ttttgtgcga ttcttctatt cggctgccac tgaatgcgaa cttgataaac
    69721 aaggacgaat caatataccc agcacgttaa gaaattatgc agctttgaca aaaggttgcg
    69781 tagtcatcgg tgtatctaac cgaattgaaa tttgggatga gacacgatgg caagattttt
    69841 ctgcagcagc agaagagaac tttgacgaaa ttgctgaaag tatgattgat ttcggactat
    69901 aagaatagga agaggctgac taatgactga aacatttcaa cactatacag tcatgttgaa
    69961 agaaacggta gatggattga acatcaaacc ggatggcgtt tatgtagact gtacactcgg
    70021 cggtgccgga catagtgaat atttattaag ccaactaagt tctaaagggc atctgtatgc
    70081 gtttgaccaa gatcaaaaag caatcgatca cgccaagctg cgtttagctt cttatgtcga
    70141 acaaggtatg gtcacattta tcaaagcgaa cttcagagaa ttagaagaac gcttgagtga
    70201 gcatgtagat aaggtagacg gcattttgta tgatctaggg gtttcctctc ctcagctaga
    70261 tgaagcagaa cgtggattta gttatcatca agatgcaccg ttggatatgc gcatggatca
    70321 gtcagctcct ttatccgctt atcacgtaat taatgaatat tcctaccatg aattagtaaa
    70381 gattttcttc cgctatggcg aggagaaatt ttccaaacaa attgctcgtg aaatcgaacg
    70441 agtacgaaaa acaaaaccaa tccaaacaac tggtgagctt gtcgaaatca ttaaacaagt
    70501 catcccagct cccgcaagaa gaaaaggcgg gcatcctgca aaaagaattt ttcaagctgt
    70561 gcggattgca gtaaatgacg aactcggtgc cgaagaggcc tctttagaac aggcaatccg
    70621 gttattgaaa gtcaatggaa gaatcagcgt aatcacattc cattcattgg aagacagaat
    70681 tgtcaaaagt atgtttaaag aatatagtac ggtacaagat ctaccaccgg gacttcctgt
    70741 catacctgac gaattccaac cagaactgaa agtcattact cgtaaaccaa tccttccttc
    70801 agaggaagag ctaacagaaa acaatcgatc acgcagtgca aagttacgta ttgcagaaaa
    70861 aataagaatg aaagaggagt agaatgatgg cagaattaaa gaaaatgcaa gattacgaat
    70921 atgatttacc tgaattggtg gatcagccgg aacaacaaat gcctgattct tcttcgaatc
    70981 aagaaatcat tcttccacaa tcaccggcaa aacgattaaa gcagatttct gctttggaaa
    71041 aaattgctgt ggcaagcgtg gcgattgcta ttgttgcttt atgtgtttta acagttatgc
    71101 tgcgcacaaa tatcagcgga gctgaaaaag aaatcacgtc aatacaaaca gaaatcaatg
    71161 ataaaaagca agaaaaaacg agtttagaac aagaaaaaaa cgaactttct cgtactgaac
    71221 ggattaaaca aatcgcagaa gaaaaaggat tgtctattaa tgacgacaat ttaaggaaag
    71281 tgaagtaaat gagtcttaaa aataaaattc ggcggtttat ggaaaagaaa aatctaaatc
    71341 cgatgaacaa tcgcaaaaaa gtaggtatca ttttatttgc tacgagtatt ggattgttct
    71401 ttttatttgc cgtccgtttc tcgtatatcg ttattggagg tcatgttgct ggtacctcat
    71461 tagctgaaaa aacaaaacag ttgtaccaag gaagtgaagt agtaaaagca aaaagaggaa
    71521 cgatttatga tcgtaacggt gtggcgctcg cagaagatgc ctcctcttat tcaattaaag
    71581 cgatactctc aaaaacatat acctctgggg ataaaaaact gtatgttgaa gaaaagaatt
    71641 ttgataaaat agcagaaatc ctgcataaga atctttctat agacaaaaaa gatgcactga
    71701 atattttaga ggacggcgca aaaaaagagc tgtatcaagt tgaatttggt agctatggga
    71761 aaaatatctc ccaagaaacc aagcaaaaca tcgaagcgga catgaaaaaa gaaggtgtcg
    71821 ctggtcttta ttttgtcgac catcaggctc ggatgtatcc aaatggcgtc ttttcttctc
    71881 attttattgg atacgcagtt ccagacaaag atgagaatgg cttagttggt aaactaggtt
    71941 tggagtctgc ttacaatgat atcttgagcg gtaaagatgg taagattatt tatcaaaaag
    72001 ataattttca aaatcctctg ccaggtacag tggcagaaga agaaaaagct gtcgacggac
    72061 aagatatcta cacgacttta gacagcagac tacaaagtta tttagaaaca ctgatggatc
    72121 aagtaaatga agaatatcag ccagaagaat tgacagcagt cctgatgaaa gcaaaaaccg
    72181 gagaaatctt ggcaatggga caacgaccta ctttcaatcc tgaaacaatg gaaggattga
    72241 ctggaaaaga tgctatctgg cgtaatttct tggtacaaga tagttatgaa ccaggatcaa
    72301 ccatgaaagt tttcactact gcagctgcta tcgaagaagg agaattcaac gagaatgaaa
    72361 ccttccaatc tggaaaaatc caagtagaag atgctacgat caatgaccat gactttggtg
    72421 aaaaaggtgt gctgaccatg cgtcaagctc tttcatggtc aagtaacgtc gggatggtca
    72481 tactggaaca gcgattaggc ggacgatggt ataactattt acaaaaactg ggatttggac
    72541 aaagtactca ttctggatta gatgatgaag taaacggtgc tttacctaca ttaaatattg
    72601 tcgaccgagc aatgagtgct tatggacaag cggtaggtgt gacgaatttc caaatgatga
    72661 aagctttcac ttctattgcg aataacggta caatgattca acctcgatat atcagcaaag
    72721 tggtggatcc ccaaactgga gaagagcgaa caactcaaac agaagttcta gggcaacctt
    72781 tttcaaaaga aacaacagaa aaagtccgtg aatatatgag agatgttgtc gaaagcgaaa
    72841 actacggtag tgcttatggt gtatatagtg tacctggata caatgtatcg gcaaaaaacg
    72901 gaacagccca aatcgcttct gatacagggg gatatcaaac aggagataca gcctacctgt
    72961 attcgattgt ggagatggtt ccttctgaag atccagacta tgtcttgtat ctaacaatga
    73021 aacaccctaa gacatatgat cgaatggcat tggctaaaat cgcaaatcca ttgatgaaac
    73081 gggcaatgga ttttaaagaa actgaagaag attcagatac agaaacaaaa acagaaaaag
    73141 tatccgtagc cgattatcgt aatcttgaag cggacgttgc agcagctgat gctcaaaaaa
    73201 gtggactgca acctgtagtg atcggtaatg gtaaaaaagt acaaaaacaa tctactgcca
    73261 acggtgatca gttgatctct ggagaaaaac tgatcctata tactggtggt gataagctga
    73321 tgcctgacgt aacaggatgg tcaaaagcag atatcatgaa gctggggaaa atcctcggta
    73381 ttgaagttag ttttgatgga gatggttatt gtgtcaaaca agaacttgct ccatatgaaa
    73441 aaatcactga agacaaactt agttttactt tagaagaata agaagagaaa taggagagaa
    73501 aagagcatgg aatggacaca agcattgatt cccattgtca gcagttgtgc aatgacaatt
    73561 gccgcaatgc cgctatttat tggttatttt caaatgaaaa agcaaggtca ggcgattcgt
    73621 gaggagggac caaagtggca caatagcaaa gccggaactc ctacaatggg cggcttagtg
    73681 tttctgatcg gctctatttt gacaggaatt tgggttggag cttggcaaaa acagctaact
    73741 cctactcttt tcatcttgct ttttgtatta gcgttatacg gagtaatcgg ctttcttgat
    73801 gattttataa aaatattcaa gaaaagaaac atgggactga actcgaagca gaaattgatt
    73861 ggacagattc tagggggaat catcttttat cttgtttacc gttctgaagg ttatccaggt
    73921 gtattgaatt tcttcggact agatctacct ttaggaatca tttatggtat tttcgctctc
    73981 ttctggcttg ttggattttc aaatgcagta aatctgacag atggcatcga tggattagtt
    74041 gctggcttag gaagtatctc ttttgcagct tacggtctaa ttgcttggca tcagcatcag
    74101 tatgatgtat taatcatttg cttaagtgtt ttaggaggtt tactgggttt cttcgtctac
    74161 aacagaaaac ctgccaagat ttttatggga gatgtcggtt cattagcgtt gggcggactt
    74221 ttagcggcaa tttctataat gctaaaccaa gaatggacat tgcttttgat tggtttgatc
    74281 tatgttatgg aaacagcaag tgtgatgctt caagttactt cctttaagct tacaggaaaa
    74341 cgaattttta aaatgtctcc aattcatcat cactttgaaa tgtgcggatg gtcggagtgg
    74401 aagattgata cagttttttg gttgatcagc attgtgactt cgttgatcac attatggatc
    74461 gtttggtagg agatgacggg aaatgaaaaa aatatcaaca tatgaaaata agaaagtgct
    74521 tgtcttagga ctcgcaaaaa gcggagtaag tgcggccaaa ttattacatg aattgggcgc
    74581 acttgtcacc gttaatgatg gaaaaccttt tgacgaaaat ccggaagcac aagagctgct
    74641 ttctttaggg ataaaagtaa taacaggtag tcatccaatc gaattgttgg atgaagaatt
    74701 ttcattgatg gtcaaaaatc cagggattcc ctacagtcat cctttagtag caaaagccca
    74761 agaaatgggt attccggtaa ttacggaagt tgagctagct tacgaagtag cggaatgccc
    74821 aattattggg attacaggaa cgaacggaaa aacaacgaca acaacgatga caggactact
    74881 actgaatgca ggagcagatc aaggaattgc acgtttagcg ggtaatattg ggtatccagc
    74941 aagtggtgta gcgcaagaag caaaatcaga agataaaatt gtgatggaat tgtctagctt
    75001 ccaactcatg ggaatcacag atttccgccc tcatatagcg gtgattacca atatctatga
    75061 agcacatatt gattatcatg gtacaagaaa agaatatgtc aaagctaaat ggaaccttca
    75121 aaaaaacatg acagaaaaag attatctgat ccttaactgg aatcagtcag aactacaaga
    75181 attagcgcaa agaacaaaag cacgcgtact gcctttctcg acaaaagaag tgttggaaga
    75241 cggtgtgtat gctgacgatt actcaatata ctataaaaaa gaaaaaataa tggaaatatc
    75301 tgaacttggc gtaccaggta agcataatgt agaaaatgca ctagctgcta tttctgtagc
    75361 aaaattgtat ggtatatcaa atgaagctat acgagaaacg ttgcattttt tccatggcgt
    75421 accacatcgt acgcaatatg taggagaaat ccaaggcaga aaattttata atgattcaaa
    75481 agcaaccaat attttagcga ctaaaatggc tctaagtgga tttgaaacgt ctaaggtcgt
    75541 gttattggct ggcggattag acagaggaaa tacatttgat gaattaattc cttcattaaa
    75601 aggaatcaaa gcaatggtcg tatttggcca aacaaaagaa aagttgatgg atgctggaaa
    75661 aaaagcaggc atcgagacaa tagtaacagc cgattctgta gaacaagcag ttcctttagc
    75721 attagaaaac agtacagatg gtgatgtagt tttattatca ccagcgaatg ccagctggga
    75781 tcaataccca aattttgaaa ctagaggaaa cagattcatg gaagctgtga accgattaaa
    75841 atagaaaaag tagaagcgag cgataaaaaa tgaaaatttt ggttacaggc ggaggaacag
    75901 ggggacatat ttatccagct cttgcctttg tcaattatgt aaagactcaa gaaccgaatg
    75961 ctgaattcat gtatgtggga gcaaaacgag gtctagaaaa caaaatcgtc cctgatacag
    76021 gaatgccttt ccataccttg gagattcaag gatttaaacg aaaaatttcc atgcataaca
    76081 tcaagacggt ccgattgttt cttaagagta tccgtcaagc aaaaaaaatc ctcagtgatt
    76141 ttcaaccaga tatcgttatc ggtactggag gatatgtttc cggagcggta gtgtacgctg
    76201 cagccaaaat gggtattcca acagttatcc atgaacaaaa cagtgtacca ggtgttacca
    76261 ataaattttt aagccgatat gtggatcgga tcgctctttc atttaaagat gcggcttcct
    76321 tttttcctga aaacaaagca gttcttgtag gtaatcctcg agcacaagaa gtagcagata
    76381 ctaaaaaatc agatattttg aaaacatttg atttggatcc agaaaagaaa acagtcttga
    76441 tttttggcgg tagtcaagga gcacttaaaa tcaatcaagc agtatcagtt tttttaagtg
    76501 aatatattcc ttcttcttac caagttttgt atgcttcagg agatagatat tatgaagaga
    76561 tcctaaataa aataaatcct gaaatacaaa atattagtgt ccagccttat atcaaaaata
    76621 tggcagaggt catggcttcc agtgatctgc tggtggggcg tgctggtgca acttcgatcg
    76681 cagaattcac agctctgggg ttaccggcag tgttggttcc cagcccatat gttacgaatg
    76741 atcatcagac taaaaatgca atgagtcttg ttcacgcagg agcagcaaaa atgattgcag
    76801 ataatgaact aacaggtgaa tcactaagtc agacagtcaa cgaaatcatg ggtgatgaag
    76861 aattgcaaaa gcaaatgtgc cgagcttcta aagaacaagg aatccctgat gcttcaaaac
    76921 gtctttatga cttagtaaaa caaataatca aaaaataaag gcggtggtct tagtgagtaa
    76981 gaaaaaagaa ccaaaaaaat tgtctcatcc gtcttctgat gaaaacaatt tgactccttg
    77041 gcaaaaggct aaccgaaaat atctggcaga acaagagatg aaaaaccaag agccaaaaaa
    77101 agaagacata acattagata cacccctttc agattctgaa gaagaaaaaa cggttcaaga
    77161 ggaacagcaa gaagaaagcc agtccgagaa aaaaatcgaa ttttttgaag agatcaagca
    77221 aaagaaaaac ggtggaccat ataacggttc ttttttgaac cggctgccca atttaaaaag
    77281 tcaacggcac aaagtactat ttcgtcggtt agctttgatc atcactgtat tgggtatacc
    77341 gctgattttt ttgatctatt atgtttctcc ttatagcaaa ttacaagcag ttgcagtatc
    77401 aggcaataag acagtcaaca gccaagaaat catctctgat acaaaattgt cattaggaga
    77461 aaatgtttgg ggacagtatt ttcatcgatc tacttatatc gatcgcctta aaaaagcaca
    77521 gccaagaatc gaaacagcaa atatacattt caaagggatg aatgaattcg atttggatgt
    77581 aacagaatat aaagagattg ctttgatcgc aaaaaacaat caatactacc cagtgattga
    77641 aaatggaaca gtattagatg aaaaagtagc aaatcctaca aaaaatctcc ctatcttgga
    77701 agagttcaaa gactctgcaa aaatcaaaga attaacaaag caatacaatc agttatcatc
    77761 agaattacaa aaagcaattt ctgaaatcaa gtacacgcca agagcaagca ataaaaatct
    77821 gatccaattg aatatgaatg acggcaatca agttattgta aatatcaata atcttgcgaa
    77881 ccaaatgaaa tattattcgc aagtagccaa agatatggat gaaaaaggtg tgatcgacat
    77941 ggaagttggt atcttctcgc atccttacgg tagcactcaa gaaacggaag aatcgggcca
    78001 atcggaagaa acaactgaaa gtgaagaaaa tgcggatcaa acaaacgaat caagtgaaga
    78061 ggcagaaacg caaaaagcac aaacacctgg atcgtctagc acaaacggat catctgattc
    78121 aaatgattca agtgaaacaa gtcaaataga agataatcca agtacaactc cgtcaagttt
    78181 aaatgaaaat tgataaaaca actttaaaaa gtaagaatgt actttctaaa aaccagtaat
    78241 ttatggtaga attggaagca gtgaatatat ctattaataa gtatatttta aaacggacgc
    78301 tagttgttcg cttgtatatg gaatagtaag taggagggaa tcccattcat ggcaaaaaca
    78361 ggaatgtatg taggccttga tattggaacg acatctgtta aagttgtcgt ggctgaatat
    78421 atcgacagcc aaatgaatat tattggagta ggaaacgcaa aatcagaagg gattaaccga
    78481 ggcattatcg ttgatatcga taaaacggtc caagcgatac aacgagcagt acgacaagca
    78541 gaagaaaaag caggtatcca gatcaaaggc gtaagtgtcg gtttgccagc aaacatgctt
    78601 gaagtagaaa attgccaggg aatgattgca gttaacggag attcaaagga aatcaccgat
    78661 gaagatgtca gaaatgtggc ttcagctgcc cttgttcgtt caatacctcc tgaacgtcaa
    78721 atcgtgtcaa tattgccaca agattttact gtcgatgggt tcgagggaat caaagatcct
    78781 cgtggaatga tcggcgtaag attagaaatg tacggtctgt tgtttacagg acctaaaacg
    78841 atcatccata acatacgtaa atgcgtggaa aatgccggat taatcgtcaa cgaaatggtg
    78901 attactcctt tagcgctgac tgaatcaatt ctttctgacg gagaaaaaga ttttggtacg
    78961 atcgtcattg atatgggtgg cggccaaaca acaacggctg ttatgcatga taagcaattg
    79021 aagtttacca atcttgacca agaaggtggc gaatttgtca ctaaagatat ctctattgta
    79081 ttaaatacgt catttaacaa tgcagaagcg ttgaaaataa actacgggga tgcataccca
    79141 gaacggacat caccagatga agaatttcca gtagatgtga ttggtcagtc agaaccagtg
    79201 aaagtcgatg aacgctactt gtcagaaatt atttcagctc gaatggaaca gattttcaac
    79261 aaagcaaaag atgcattgga ccaaatcgaa gcattagagt tgccaggtgg cgtcgtattg
    79321 acaggcggag ctgctagtct tcctggtgtt gtggacttgg cacaagaaat cttcggcgta
    79381 aatgtaaaat tgtatgttcc aaatcacatg gggctgagaa acccggtatt tacaaatgta
    79441 ataagtatcg tggattattc agcaaacttg agtgaagtgt atcaattggc aaaaattgct
    79501 gttacgggtg aaacctcagc agctcgtcaa atggtagttg aacaagaaac aacaaacaca
    79561 tatgagagct atgaagcacc tgaagaaaca atctacgatg agccggaacc aaaagagtcc
    79621 ggagaaaatg taaaaaataa aatcaagggt ttctttacaa atatttttga ttaattcatc
    79681 ctgggaggaa taagatatgg aattctcaat tgataataat atcaatgacg gcgcagtaat
    79741 caaagtcatc ggagtcggtg gtggcggtgg aaatgctgta aaccgaatga ttgaagaaaa
    79801 cgttaaaggt gttgaattca ttacagccaa cacagacgtg caagcattaa aaaattcaaa
    79861 agctgaaaca gttatccaat taggccccaa atatactcgt ggtttaggtg ctggttctca
    79921 gccagaagtt ggacaaaaag cggcagaaga aagtgaacaa tccttacgcg aagctttaga
    79981 cggtgcagat atgattttca tcactgcagg aatgggtgga ggaaccggta caggtgctgc
    80041 accaatcgtt gcaggtatcg cgaaagaatt gggcgcattg actgttggtg tcgtgacacg
    80101 tccattcact tttgaaggac cgaaacgtgg ccgttttgct gcagaaggta tcgctcgttt
    80161 gaaagaaaat gtggatacat tattaattat ctcaaataac cgtttattag aagttgtaga
    80221 taaaaagaca ccgatgcttg aagctttccg tgaagcagat aatgttttac gacaaggtgt
    80281 acaaggtatc tctgatttga tcacagcgcc aggttacgtt aaccttgact ttgctgacgt
    80341 gaaaacagtg atggaaaacc aaggtacagc attgatgggg atcggtgtgg ctagtggaga
    80401 agatcgcgta gtagaagcaa cgaaaaaagc aatctcctct ccattgcttg aaacatctat
    80461 tgatggagct gaacaagtac ttcttaacat cacaggcggt ttggatatga cattgttcga
    80521 agcacaagat gcttcagata tcgtagcaaa tgcagcaact ggcgatgtaa atatcattct
    80581 aggtacatct atcaatgaag aaatgggcga tgaaatccgt gtgacggtca tcgcaacagg
    80641 tatcgatgaa tcaaaaaagg aacgcaagtc tagccgacca gctagacaag cacaaatgca
    80701 atcacctgct caaaagactg tattagatat ggatcaagct aaaccaactt cttcagaaga
    80761 agaaaacagt tttggcgatt gggatatcag acgtgaacaa aatgttcgtc ctagagttga
    80821 tgattccaat tttgacaata tcgaaaaaaa agaatttgat acattcaacc gcgaagaaac
    80881 aaaatctcat ggcgatgatg aattaaatac gccaccgttt ttccgtcgta aaaaataaag
    80941 gagaggaaga gcacatgatt gctgacaact tgcagaaaat caagcaagaa attcaggatt
    81001 cgtgtgctct tgttcatcgt gatccgaaag aagttacatt agtagctgta acaaaatctg
    81061 ttgaatccgc tcaagctgaa gaattggtta gagctggcgt tatgaattgt gcagaaaacc
    81121 gagtagataa attattagaa aagaaacaag atttatttga ttttcctgaa ataaagtggc
    81181 atttaattgg taatttacag cgcagaaagg taaaattgat tgtaaatgaa attgattact
    81241 ttcatgcgtt ggacagttta agattagcag aagaaatcca gaagcggtta gagaaagaat
    81301 tatcctgttt tattgaagta aatgtttctg gtgaggaatc aaaacatgga atttcaccag
    81361 atgagctttt accgtttgtg gaatctttag ctgcctgcac aaaaatcaag gttgttgggt
    81421 tgatgactat ggcgcctaaa gaagcttctg atgagcaaat ccataaagtg tttggtacgc
    81481 tgaaagaatt gcgtgatctt gttcaagcaa aaggttatgc ccatgcacca tgtagtgaat
    81541 taagtatggg gatgagtcaa gactttcaaa ttgcgattga agaaggtgca acatttatcc
    81601 gtgtaggaac agcgctattc aaagacgaat aaaggaggaa caaaaatgcc gcttttaaac
    81661 agaggagcaa ttgctaattt tttcggatta gctgatgagg aagagtacga ataccaagat
    81721 tatcctgaaa caacaaaaaa ggctgtacag ccaactaaaa aaaatacaac acagaatcaa
    81781 tcaactcatt ctgtatctgc tgcgaatact catgaaaaac aaaaaacggc gacttcacgt
    81841 cctgtaacgc atgaaagtat tcagccggct gaaaagaaaa aagtaattga actacatcaa
    81901 tcacctacaa aaactgtagc gaaagaaaga acagcttcaa gaacctctac acaacctaaa
    81961 gcaaatcttg ctggaaaaat cactgtaatg gaaccaagag cttattctga agctatggcg
    82021 attgctaaac gaatcattgc tggagaagca accttagtga attttcattt agtagaagaa
    82081 aaacaagcga gaagaatcgt tgattttcta acaggaacag tttatgcact agatggagat
    82141 atcaaacgtg ttggagatga gatttttctt tgtacaccga ctgggatgga gattgacagt
    82201 tcaaccgctc aatcttttgc agatgcgaat ttgtttgatc tgtaagagga ggaactacga
    82261 tttatactat tgcactatta cttcatttac ttcaacgggc agcctatttc tatagcatta
    82321 tcttgatggt atatgcattg ctctcttggt ttccaggcgg gtatcaatca gggctaggac
    82381 gattattagc taagatctgc gaaccgtata tcagtttgtt cgatcgtctg cctttgagga
    82441 ttggaccctt ggatttcaca attttagggg caatcctgat cttgaactta gccgtacaag
    82501 gtttagcaca gatcgttata tggataactg tccatttagt ttattgattg aagcaacaaa
    82561 atctttattc tcagaataga taggagggga aaattttgga tgcaaatgta taccagcact
    82621 ttcgggcaga tgaacgtaca tttatcgatt cggtaggcga ttggattgaa caggttcaag
    82681 gacaatatgc accctatctg accgaatttc ttgacccaag acaatcctat attttagaaa
    82741 cactgattcg acaaagcagt gatttgcgtt tcatgtttta tggcggatat gaacaggcag
    82801 aaagaaaaag atgtttgatt ttccccgatt attacgaacc tgtagaggaa gattttgaaa
    82861 cagcattgta tgaaatccat tatcctagca aatttgccag cctaagtcat gggaaaatcc
    82921 ttggaacttt agtgggaacg gggatcaaac gctcttactt tggcgatatc atctcggacg
    82981 gtgatcgctg gcaagtattt attgcaaatg aggtggatca ttttgttgct gcacaagtaa
    83041 caaagattgg aaaggttgct gtacgcttgg aaccaatcaa atacacagaa atgattatgc
    83101 cgaaagatag ctggacacaa gaaagaggaa cagttagttc catgcgacta gacagtgtga
    83161 tctctgagat ttataatatt tccagacagc ggtccaagca gctgatcgaa gctggtaaag
    83221 taaaagtgaa ctggacagaa aatacaagac ctgattttgt acttgaacta ttagatatta
    83281 tttcagtcag aggttatggc agagtccaga tccaagaact tgaggggaag acgaaaaaag
    83341 aaaagtacag ggtactgttc ggtgtattac gtaaataaaa taaaaaggtg gtttactcat
    83401 ggctttaact ccattagata tccaaaataa gacattcccg acaaaaatgc ggggatataa
    83461 tcaagacgaa gtagatgatt tcttagattt agttgttcgt gactatgagg aattgactca
    83521 aagaaatcga gaattagaaa aagcagtcaa acattctgaa gaaaaacttg agtacttcaa
    83581 tgaattaaaa gatgctttga accaatcaat catcgtagct caagatacgg ctgataaagt
    83641 aaaaacaagt gcaagcaagg aatccgaagt gatcgttact tctgcacaaa acaaagcaga
    83701 tgagttagtt gcgaacgctg aaaaacgtgc acatcaatta acaactgatg cagaagaaaa
    83761 agcaagaaaa atcttgacag atgcaacaga aaaagcaaga cagcttgcga cagaaactga
    83821 agatcttaag aaaaaaacac gagtattcca tcaacgtatc agcttgatgc ttgagtctca
    83881 attagaacaa gtgaaaagtc cggaatggga tgaaatttta caaccattct ccagctacgt
    83941 gactgacagc catgaagtga tcaaagaagt tttagcaaaa cagcttgaca atgaaaatga
    84001 tactgatgta aactcagaca caggagtcat agaagcacct atgacggcat ttgatacaca
    84061 ggctattgat atctcgatcg tgcctggtga aaatgaaaac gagtagaaca gaaaagcact
    84121 ttgttattct taaagcgagc cgatgagagt ggaagttcgg taagacactg catggtgaaa
    84181 gatcctctac ttgagacctg cttttccgaa attagagtaa gaagcagcgg ctgacctcgt
    84241 tattggtcac agagagtttg cactagatag atgcaactaa atttgggtgg taccacggca
    84301 tgttcgtccc ttgcggctga acatgctttt ttgtgtccgg aaaacaaata aaggagtgta
    84361 tggttgaatg aaaatgaaag aaaccttgca attaggaaaa acaaaattcc ctatgcgtgg
    84421 taatttgcca aaccgagaag gcgagtggca aaaagaatgg gaagaaaatc gaatctacca
    84481 aaaaagacaa gagttgaacg aaggaaaacc tagctttgtt cttcatgatg gacctccata
    84541 tgccaatggt aatatccatt taggacattc attgaataaa atcagtaaag acattatcat
    84601 tcgttcaaaa tcaatgtctg gctatcgtgc accatatgtt ccaggatggg atacacatgg
    84661 attgccgatt gaacaagtat tggctaataa aggcgtgaaa cgtaaagaaa tgtccatggc
    84721 agaatacttg gaaaaatgtc gtgaatatgc actttcccaa gtagataagc aacgagcaga
    84781 tttcaaacgc ctaggagttg caggagattg ggaacatcct tatgttacat tagatccttc
    84841 ttatgaagct gcacaagtac gcgtatttgg taaaatggct gaaaaaggct atatttacaa
    84901 aggattgaaa ccaatttact ggtctccgtc aagtgagtct tctttagcgg aagctgaaat
    84961 tgaatataaa gatgtaaaat ctccatctat ttttgtagct ttcaatgtca aagacggcaa
    85021 agatattctt gatgaagata cagcttttgt catttggacg acaacaccat ggacattgcc
    85081 agcaaaccaa ggtattgctg taaatccaaa atttacgtat gtattggtgg aagccgatgg
    85141 ccgtaagttt gtcgtagcga aagatttgct agaaacagtc caatcagaaa tcggttggga
    85201 aaatgtaaca gttctaaaag aatttgctgg acaagaaatg gaatatatga ctgcaagtca
    85261 tccattctat gaacgtgaat cacttgtgat tttaggcgat catgttactt tagacgctgg
    85321 tactggatta gtccatactg ctccaggaca tggggaagat gactatatcg ctggtagcaa
    85381 atataaacta tctgtagtgt cacctgtaga ctcaaaagga ttgtttacag aagaagcacc
    85441 tggatttgaa ggtatctttt atgacaaagc aaatcctatg atcactgatc tattaaaaga
    85501 aaaaggagct ttgctgaagc tagatttctt tactcatagt tatcctcacg attggcggac
    85561 gaaaaagcct gtgatctatc gggcaactcc acaatggttt gcatctatcg ataaattccg
    85621 tcagaatatt ttggatgaag tagaaaaagt agagtgggtt atcccatggg gtaaaacacg
    85681 tttgtataat atgatccgtg accgcggcga ttgggtaatt tcccgtcagc gtgcatgggg
    85741 agtaccactt ccgattttct atgctgaaaa tggagaagca atcatcacac cagaaacaat
    85801 cgaacatgtg gcaaaattat ttgctgaaca tggatcaatt atctggtttg aaaaagaagc
    85861 gaaagaactt cttcctgaag gatttaccca cccaggttct cctaatggcg aatttacaaa
    85921 agaaaaagat atcatggatg tctggtttga ttctggttct tctcatgaag ctgttttacg
    85981 tcagcgacca gaattatcat tcccagcaga tatgtattta gaaggatcag accaatatcg
    86041 tggctggttc aactcaagta tcacgactag tgtggctatc aatggtgtag caccatacaa
    86101 atcagttatt tctcaaggat ttgctttaga tggtgaaggc cgtaagatga gtaaatcttt
    86161 aggaaacatc attgcaccag aaaaagtgat caaacaattt ggtgcagata tccttcgctt
    86221 atgggtatct agtgtagatt atgaagcaga tgttcgtgtt tctatggata tcttaagtca
    86281 agtggcagaa gtatatcgta aaatcagaaa tacgatgcgt ttcttattag cgaatacaga
    86341 agatttcgat cctaaaaaag atactgtttc gtacaatgat ttacgttctg tagacaaata
    86401 tatgaccgtt cgattgaacc aagtaatcaa agaaatccga gaagaagggt acgacaaata
    86461 taacttcatg catatttacc gtacagttat gaacttcttg acggttgatc tatcgtcatt
    86521 ctacctggat tttgctaaag atgtagttta tattgaagca gaagatgatt atcaacgtcg
    86581 ttgcatgcaa actgttttct atcaaacagc tgtagctttg acaaaattat tgactcctat
    86641 cattccgcat acagcagaag aaatctggtc attcctgaaa gaagaagagg agtacgttca
    86701 gttaagcgag tttcctggtt atgaagagtt tgcaaaccaa gaagaattga tggatacctg
    86761 gactgctttc atggacttcc gtgataatgt cttaaaagca ttggaagaag caagaaacag
    86821 caaattgatt ggtaaatctt tggaagcaaa actaactgtt tatccaaaac aacaagttcg
    86881 tgaaatgtta aaagctttgg atgcagatat tgcacaatta ttgatcgttt caccagacta
    86941 ctttgaagtt atggcagcag atgaacaagt gccagataac gctatggtat ttgatgatgt
    87001 tgctattaca gtggaaaaag cagacgggga aacttgcgat cgctgtcgcc aagttcgtaa
    87061 agatgtagga gtagatgaaa aacttcctca tctatgcggt cgttgtgcaa aaatcgttga
    87121 agacttctat cctgaagctg tagctgaagg attcgaagaa aagtaaaagg gaaaaggggg
    87181 tgtgacatgt tctttgtcac accccctttt gttatcaatc gtttaatttt ccacgttcac
    87241 gataccagtt atctggttgc cagatccatt cgaatccgtc tttttcaagt agttcgaaag
    87301 ctgctttagg tcccattgat ccagctttgt agttgggaaa atccggttgt gtttggtccc
    87361 aagcttttcg aatgacatcc acgatatgcc aagattgagc gacttcttcc caatgagaga
    87421 agttcgttcc atcaccattc aacgcatcta atagtaattt ttcgtaagct tctgggctat
    87481 tttcaaccat ttctgcacta tttctaaatt ccaatttgat tggttccgtt tcaaatcctt
    87541 gccctacttc tttcccattc aaggataaag aaaatccttc agttggctga atatagatcg
    87601 ttagaacatt aggtggaagt gtcgtatcgt cacatggttc atcgacagat gttttgaata
    87661 cattaacagg aacttgtttg aatacgatgt tgatccgagt ccctttttca gtcaaacgtt
    87721 tgcctgtacg tacatagaaa ggaacacctg accaacggaa gttatcgata gtgaatttgc
    87781 ctgcgacgaa tgtttcagtc tctgattgag catccacttt gtcttcttcg cgatagccct
    87841 tgaattgtac accatccaat tcaccttgag catattgccc gcgaacgaag ttttctaaca
    87901 cttcttcttc gttataaatg cggatagctt tcaatgcttt gatcttttct gtacggattt
    87961 ctttttcgga aaatgctact ggcggttcca ttgcaagtaa tgctacaacc tgtaaaatat
    88021 gattttgcac catgtcttta agtgcgccac tatgatcgta gtagcccccg cgatcttcta
    88081 caccgaggtt ttcgccaaaa gtaatttgga tattgtcgat atagcgattg ttccattgag
    88141 cctcaaaaat attattggca aaacggatag ctgagatgtt ttggatcatt tcttttccta
    88201 aataatgatc aatcctgaaa atatcttgtt ctgggaatac ttctctgatt tgctggttca
    88261 attcaaaagc agactggtaa tcagaaccga acggtttttc tatgatcaaa cgattgaagc
    88321 cattttttgt cataatattt tgtgatttca aatgagaaac gatcgttcca aaaaattgag
    88381 gtgccatagc caaataatag acacggttac cgtttaattg atagtgtcca tctaatcggt
    88441 cagacaattc ttttaatgtc tgataatgcg ttgaatcatt tacatcatgg gattgatagt
    88501 aaaaatggct tgcaaaggta gttgcttctt catctgaagg attcaatgca cggattgttt
    88561 ctttgacaac ttcacggtag tgctcatcgc tccagggacg gcgagcggtt ccgattacag
    88621 caaaatgctc gcctaaattt ccttttctgt aaaggcggaa caaagacggg tacaatttac
    88681 gctgggctag gtcacctgta ccgccgaata tcgtaaacaa tacatttttt tcattagaca
    88741 tgtggataca ctcctttata ttttatcgac aaaaatcgtg ctggccgcct taaagctgac
    88801 ggggattttc tttctatcat tttggatagt gatcggtcct tcataagctg cgatgtcaac
    88861 gatctcatat tcttcgttga tattcaggtc aatagtgact aagtaatcca acaattcttt
    88921 ttcatcaagc actcgtgcga tacgcacttt tgtaccgaca ggataggact ccaatgtttg
    88981 tcggcgttct tcatggacaa cttcctcttt tttaggaatc gatcctccat gaggacaatg
    89041 ttcaggatga ttcaaatagt tttctaaatg atctgcaaga tgttccgaag tcacatgttc
    89101 caatacttca gcatcatcat ggacttcatt ccagctatag tctaaatgtt caactaaaaa
    89161 aacttcccat aagcgatgtt tgcgaatcag actgctagct ttttgcagtc cgcttgcagt
    89221 caattgtaca ccttgataag gggaatgttc tacaagctct tctttcacaa gtttagaaat
    89281 catttcactg acagatgcag ctgagacatc tagactagat acgatttgtt tattgttgac
    89341 tttcgttgta tctccaccta gttctaaaat gattttcaaa taatcttctc gatttggtgt
    89401 catattcgat catcctttca tggtaaaaaa ccatcattag taagtgtaac aaaaaaaacg
    89461 ttaattgact atttttctaa ataaaaaaca aaggattttt agacgttttt acaacaaaaa
    89521 acgaaagatg atagagaaga ctcattcttt cgtttataaa ggatatatat atacattggg
    89581 agggatctat ttttcagata acaacttata tgaagtgtct gcagattcgt cataaagagt
    89641 ttgttcggga taagaaaaga taagataaaa accatactga tcacgtacga ctaaacgata
    89701 ttcatctatt tctaccacag atgtgccaag agactgaccg ttgatcaaaa acgtgtaatc
    89761 agatgtaatc tgtaattgtt gtttttgctg gctatcacta aagaaccatg taccttgata
    89821 ctttgagagt ccttctgact tttccgcttg ttttttcttt ttcaagtaaa taaaacttga
    89881 gagaacggta atgagtgaac caagaaaata gatcattttt tttatcacca aatcactcct
    89941 ttatgagaaa ataatcgcat agacatattc tttcttcttt atttcattgt accgaataaa
    90001 agctaaaatt tctctaagac tttcgactgg tttttttact gtttttctac aaattatgat
    90061 aggatacata gtaggaagaa aggtgacata atttgaagta tcagcaagtg gaaatagctt
    90121 tttttattga ccgcccgaat cggtttatag cacattgtat gaaaaaagac ggagaaataa
    90181 ttattgcgca tgtcaaaaat acaggtagag gaaaagaggt cctgatacca ggcgctgaag
    90241 tggctattgt atttgctcct ggacctaaac ggaaaaccgc ctatgatctg attgctgtaa
    90301 aaaagaaggg tgactggttt aatatcgata gtcaattgcc taatcggctg gcaattgatg
    90361 gtattttaga cggcacgatc cttttaccag gattaactgg tccatttacg gtatacaagc
    90421 gtgaagtaac ttatcttcac tccaaatttg atatttattt agagacggtg gtcggacaaa
    90481 aagcatttgt tgaagtcaaa ggtatgacac ttgaaaataa agcgattggt gcttttcctg
    90541 atgcgcccac actcagagga ttgaaacata taggagaatt aacgtatgcc gcacaagatg
    90601 gttatgccgc ttatgtcttg tttattgctc agttcgaaca tcttcatctg gcaacgatcc
    90661 atgaagaaat gcaaccagca ctagctgata tggttcgaca tgcgcagcaa agcggagttc
    90721 aaatcctcgc ctataattgt caagtatcgg cagatgaggt aactgtcaag caggccattc
    90781 catttgatgt agatatccct tttgaagatc ctatacaata gaaagaaggt aaaataatga
    90841 tcaacttagg tattatcgga acaaattgga ttactcatca atttgtccaa gcagctttaa
    90901 gcacaaaaaa agatgaattg acagcggtat attctagaca tttggaaaaa gcacaggaat
    90961 ttggttctca ttatgaaggg gatatcgaat tcgcaacaga tttgaagact tttttcaata
    91021 ttactcatat ggacaccatt tatattgctt ctccgaatag tcttcacttt agtcaagcta
    91081 agcaagcaat tttggcagga aaaaatgtga tagttgaaaa gccagctttt tcgacgccaa
    91141 aagaaatgga tgaaatcatc catttggcaa atgaacacaa tgtgtatttt tttgaagcag
    91201 caagaaatat ccatgaatca ggttttaaaa agattgccga ttacttacca ttaaaagacg
    91261 agataatcgg tgcaaatttc agctatatga aatattcttc gcgctatgac caagtattag
    91321 atggagaaga accgaatatc ttctcgactc atttctcagg tggtgcattg atggatttag
    91381 gtgtttacct tgtatatgca gctgttgctt ggtttggaat gccaaaagaa gtccattatt
    91441 tcccaagaaa gatttctact ggtgtagatg gtcttggatg ggggatctta cgttatgaga
    91501 attttgatgt atcgatccag ccaggtaaaa tcggtgattc ttatttaccg tcagagattt
    91561 attttgactc aggaacgcta gtgatgaatg gagtcaatgc aattgaacaa gcacaatttc
    91621 atgatcgcgc gcataaagaa atcattgatt tggcggtaac agctgcagaa aatccaatgg
    91681 cagatgaagc agaggatttt gccaatgtca tggctcatcc gaaagatcca gcttggggat
    91741 tgttgtatga agagtggatc gagctagcta gaaatgtgaa ccaagtgatt tatgatttaa
    91801 gaaaaaatgg cggcatcaaa ttcgatgcag ataatgagga agatttttaa tgaacgaatt
    91861 tgtacaagta tttcccgaaa attggcagaa aaaatatgag gataaagggt ttatctcacc
    91921 ttctcttatt caacgagcag tttttcagcc actaagtaat aaacaaagta tagtagcggt
    91981 ttctcctaca ggttcaggta aaacactggc ttatctttgg cctctactac taaacgtgga
    92041 accaggtgaa gcaagtgcgt tggtcatttt tgcttcttct caagaactag ctattcaagt
    92101 agcagatgtt gcacgtgaat ggggaaaaga caaagagttg aaagtccaat ctttggtggg
    92161 cggagccaac gtcaaacgtc agattgaggg tttgaaggaa aaaccagaaa tcttgattgg
    92221 tacaccagga agaatattgg aattgatgaa agcaaaaaaa ataaaagcac atcaagtgaa
    92281 aacaatggta tttgatgaag cagaccagct atttgacgct gggaacagcc aaatcattga
    92341 tcaaattctt catcaagctc caacagagta tcagctagct tttttttcag cgacagcaga
    92401 tcgttccctt gaaagcattg aaaaaatcac tgggaaaacg tttgagacaa ttgacgtgac
    92461 agcagaggac gattctcgaa aaggactgag acattacttt ttacgtgtac cgatacgaaa
    92521 gaaagatgac tacttgagac gtctcacgca tatagaagat tttcatggtc tgattttctt
    92581 taatcaactg actgaattag gcgtaatgga agaaaaattg ctgtatagag gtgtaccggt
    92641 aggaagtctg gcctctgatc agaacaagct actccgaaaa gcagcgctag aacaattcaa
    92701 aaagaaaatg gtcagagcac ttttgaccac agatgtggcg gctagaggtt tagatattac
    92761 aggtcttcct tatgtagtga atgcagaagt tccgttaagt gaagaagctt atttgcatcg
    92821 ttcgggaaga actggtcgaa tgggtaatga aggaatagta attacactcg tacaagataa
    92881 taatctaaga gatttaaaac ggcttttacg tccatcaaat ataacacttg aagagatttt
    92941 tttatacgga ggtaagctgc aaactgagca gccaaccaaa gaagatgcag ctcctgcagt
    93001 aaataaaaag tatgcgaaaa ctttttctgg aaaggagcag aacccagaat ataacaaaga
    93061 aaaaataaga aaaaaagtta aaaataaatc aaaaaaagag agaaataaag gagcaaggcg
    93121 caaataagcg cctttttatg ctatgattat gaaaacggga acaaaattgg ttgccagagg
    93181 aggggttatg tgaaagaacg tcaagaagag atcttgcagc tattgacaga aaaccaacaa
    93241 ggattgacag caagtgatgt agctgagcgc ttaactatcg atcgaagcaa tgcaagccga
    93301 tatttaagtg aactatacaa ggcccatcat attgtaaaaa ccgctggccg accagtcgtt
    93361 tactctttgc caacggaaaa gtcaaaatct gatgaagtgc atgtcgactc ttctacgcaa
    93421 gtgacttttg aaacactcgt tggagaaaat gattctttaa aagtcagcat acagcaggca
    93481 aaagctgcga ttctttatcc accgcggggg ttgcatacga ttatttttgg agaaactggt
    93541 acagggaagt cgatgtttgc tgaatgtatg tatcattttg caatcgattc agagatgctt
    93601 tctgcagatg cgccatttgt ttctttcaat tgtgcggatt atgctcaaaa tccgcaactg
    93661 ctctttggac acatctttgg gatcaaaaaa ggggcttaca caggagcagc tcaagatagt
    93721 cccggtctaa tagccaaagc agacggcggt atattgtttt tagatgagat ccaccgttta
    93781 ccgccggaag ggcaggaaat gctgtttact ttcattgata aaggtattta ccgtccgctt
    93841 ggagaaagtg cacaagtaca tgaagcatct gttcagatca ttggggcgac gactgaatct
    93901 tcagaaagtt tcttatctac gttcaatcga cggattccta tggcaatcac cttgccgaat
    93961 cttgcttcac gttcactgga tgagcgttat gaaatcatct ctctttttat caaacaagaa
    94021 gcgaatcgtt tgaatcaacg tatcgatatc gaaaaagaag cgattcttgc cttcatgctt
    94081 tatgatgcgg aaggaaatat cggtcaagtg aaacgagact tgaaactagt ctgtgcaaaa
    94141 tcttttttac attaccgtac tcatcatgag aaaaagctaa tcattcgaaa agaagaactt
    94201 tcccttcaag tacaaaaagg attactgaaa atcaaggaaa taccggaacg tctcgaccga
    94261 ttcatggaca gcaaaagtca gtatttgaca tttgaaccag gatttgctga tgttgtctgg
    94321 tcacaagatc cagaacgaaa catgcaggtc tataacgata ttgaggaaaa agtcacttct
    94381 ctttccgaaa ccggtgtgga gaacattgat ctagagaccc tcatttcaaa agatgtggat
    94441 gcttatttcc agacatatgt caaagaattg actaaaagtt cgattcccaa agatcttttg
    94501 ccagatgaaa tctggcggtt aaccaatcaa ttgtatgatg tggctgaaaa acggttagac
    94561 cgtatttata atgaaaaagc tcgttttgct tttgctttgc atctgcaaag tacattggat
    94621 cgtgtgagag aaggtcatat gatcgtccac ccagatttga ataacgtacg gaaaaatttt
    94681 aagagggaat tccaggtagc aatcgatctt tcaacgatca ttgaagaaga agaacaagtt
    94741 gagattcctt ttgatgaaat cggctttatt agtatgtttc tttctatcaa tctaggagaa
    94801 agtgagcctg ttaaagaaaa caaagtagat gttctcatat tgatgcacgg cagacagact
    94861 gcttcaagca tgttggagat ggcacaagaa ctattaggaa caaaagtagg gaaagctttt
    94921 aatatgccac tggttatgga agttcaaaca atgtatgaag aagtgttaca atatgtcaaa
    94981 aactatcaag agcatttgac gaatggccta ctcttgttaa cagatatggg atcattaaac
    95041 accttcagtg atttgattta tgaagagact ggcattcgga cgaaagctat cacgatgaca
    95101 agtaccatga ttgtgataga agcgatacgg atggcaagtg ttggaagaag cttagaagat
    95161 atttatcaaa atatccagct ttcctttgaa tcgatcgtac gtgatcagtt caaagcggaa
    95221 aagtctgaaa ctttacagcg taaaaaagcc gtaatcgtga catgctttac tggtgaagga
    95281 gtagctgcca aattatatca gcgtattatg ccagtgatta atcaaaataa ggtagaactg
    95341 atccagatgc agtttttaga acgtgaatca ttcaaaaaac acatcgatgc cttattggaa
    95401 gaatatgaga tcaaagcaat tgcgggaaca gttgatgttg attatcaaaa tatcccattt
    95461 ttttcagcct atgacgtttt tgatgatgaa aaactaaata ttttaaagcg tatagctgat
    95521 gatgagatcc cgacagctaa aattgtcgat tcacttgctg gatcattaag cgatgtcttt
    95581 tctattgatg aactgatccg ttcattgcaa aagacagttc agcagatcca gaccgatttg
    95641 tcgattatcg tggaacctgg agtagatact ggaatcgtta tccatttagc cttcatgtta
    95701 gacggattga tcaaacaaga aagccatcgg caatttgaga aactgtctat tttctcaaaa
    95761 atttatcgtt tggaaatgga tatcgttcgg gcaaacttga tggcactaga acgaaaatat
    95821 caggtaaaaa ttccagaaga tgatatcgca tttcttacac aaatgtttct tgaaaataaa
    95881 ataaaaaaat gaacacacta atcatactgt ttacacacta aacatctgtg tgcgcactat
    95941 aaaaaagagc taaaaagcat gaaaacgcta tttcagctct tttttttatt ggcatgcttc
    96001 ttgcgttata taaaagtgta aaaaaataaa aggagtgtta aaaatggcaa aaaaaacaat
    96061 catgttagtt tgttcagcag ggatgagtac gagtttattg gtcacaaaaa tgcaaaaagc
    96121 agcagaagaa aaagggatgg aagccgatat ttttgcggtc tctgcctcag atgcagataa
    96181 taatttagaa tctaagaatg tcgatgtatt attattaggt cctcaagtac gtttcatgaa
    96241 agctcaattt gaacaaaaac ttgcgcctaa aggtattcca ttagatgtca tcaatatgca
    96301 agactatggc atgatgaacg gagaaaaagt tcttgcacaa gcagaaaatc taatgaaata
    96361 aatcaagtat gcagttgggg gtataacaac gtggaagatc aacaaaatct agaagccatc
    96421 atggggttaa tcatgtttgg cggtaatgca aagagcgatg caatggaagc gattgcggct
    96481 gctaaaatcg gtgattttga gttagcggat aggaaaatcg ctgatgcaga agaatcactt
    96541 atacaagcgc atcatgcaca aacagacatg ttgacacaag aagcacaagg aaatcatatg
    96601 caagtgacat tattgactgt tcacagtcaa gatcacttaa tgacatctat tgcgtttact
    96661 gatttagcaa aagaaatcat cgaactttat cgtcgcgtat acagcgaata aatacaactt
    96721 cttttttgaa cggaagaaga aaaatttttg aacggatttt ttattttgtt ataaggagaa
    96781 ctctctttat ataaaaaact tataggagga agtaaaaaat gaacggacta tcaagttgga
    96841 tggagaaata catcctgccg gttgccgcaa aaatcggagc gcaaaaacat ttagttgctt
    96901 tgcgtgatgc ttttatcggc atactgcccg caacaatggc gggatcagtc gctgtaatga
    96961 tcaatgcaat tattcgtgat ttaccgcaac agtttaacag tacctatgct gacagtttag
    97021 cagcagacaa aggaatcttt gccgtattga atgtcatcat cggaatcaat ggttttgtct
    97081 ggaacggtac actagcaatc gccggattga tctttgcctt ttcttggggg tataatcttg
    97141 cccgagctta tggagtaaat gatctagctg gggggatcgt tggtttagct accttgattc
    97201 aaggtatttc ctttggtcca gcattatcag cagcattaga tgtgaatgtt ccttcaaatg
    97261 tcgcagatgc aatcaatagt tctgagattg gtgcaacgat tgcagatggc acactgtcag
    97321 ttggattatg gggttggcta aaactagatc atttgaatgg aaacgcttat tttacagtta
    97381 tgatcatggg agctatttca gtcattattt tttgtaaatt gatgcttgcc aacattacga
    97441 tcaaaatgcc tgattcagta ccaccagcag tatctaaagc atttgcagcc attttaccag
    97501 cgacgatcgc tttatacgtc attgctatta tcaattatat cgtaggtcgt gtagctgatg
    97561 ggcaactgat cattgatttg gtgcaaaaat atattgcaga accattccta ggattatctc
    97621 aagggttggg agcagtattg atcgtcacag tatttgttca agtattctgg ttctttggta
    97681 ttcatggatc aaatgtattg gcaccagtgc tagagggaat ctggggacaa gcacaactaa
    97741 tcaatattga tattttccaa aaaggttata acggaaaaac tggtacacca gccgtgttag
    97801 atgcaatcga agatggaaaa gcttatatgt gggtccgcgg atcgttcgat gcttttgcat
    97861 ggtttggcgg atcaggcgga acgatcgtct tactgatagc tatcttgatt ttctctaaac
    97921 gtgcagatta tctaacagta gctaaattat ccattgggcc tggtatcttc aatatcaacg
    97981 aaccagtgat gtttggtctg ccaatcgtat tgaatgcaat catgtttatc ccattcttga
    98041 ttgctccagt agtagcaaca gcaattggat ggacagctac ttatcttggc ctagtcgctc
    98101 cggtatcgca gcaagtcaca tgggtagtac cgccgttctt attgtcattc ttagcaacag
    98161 gagcggattg gcgggcaccg atcgtaacat tagtatgtat ggtcgtgact ttcttgattt
    98221 gggcaccatt tgtcatctct gcaaacaaaa tggaccctgc cgcaggcgaa caacaataag
    98281 atgaacgtga ggagcgggac gctttaagtt tcgttcctca taatgaattt tcgaggagga
    98341 actgaaatga ttacaattgc cagtgcaatg caacaagatg aaatcaaaga attgttagaa
    98401 ggatacaatg aagaaggaat gacttttaca tttaaagaaa aacaaggaat caagctgttc
    98461 tttgaaacaa gtgcagaaga tccggaagtt gcggctaaaa aagcaaagga actaatcaaa
    98521 gcacagcctt ggggaacagt cctttatttt caatcaacag ctgtttagaa aatggtttaa
    98581 aaagatagga tggttgagat gataaaaaac ggtttatttt tatgtagtat tggttctttg
    98641 atcgtgttgt atagtttgaa tccacattcg caaaggtatg atttgtatag tatggtcaca
    98701 ggtctttttc taacaggatt aggaatctat ttcttcatga aggggaaaaa aagagaagaa
    98761 gcaaaggaga aaaataacta atggaaatca cgaaaaaatt aaatattcca gcatcgtttt
    98821 tttacgataa agttatggac tctgtccttt tcgatgtacg taaagcgacc ggcaaatcag
    98881 taactagaaa acagctgaaa aatttggagt acgtcaaaca attctcgcaa aataaccggg
    98941 ctcgcataaa aatcgaagaa gtcattgaaa accagtctta taagtttcgt acatcgacaa
    99001 cgaagaatga attcgtcgtt cattatcaaa tcaaaccatt ggacgattcg acctgtgagg
    99061 ttcattacac agaaaaaatg gagtcttatg gcatgcttca aaagttgaat gatatgcttt
    99121 taggaacaat cttgatgtat tttaaacgga gacgtttcaa aaaaatgcta gatatgatcg
    99181 aagcaacgta ttaaatcaat gaaacatggt actatttagt tattgaaaaa tgaagtaagc
    99241 tagaaggaat ttttcatagg aagatagatc tttcctgcga atcctcacta gcttttttgt
    99301 aggaaggggc agcaaaatga caaacaaagt aagagagcta ggtgtatctt cgattgagga
    99361 aatgtttgat ttagccactt atgcatttaa tggggcagat acacctgaaa ggcgagaacg
    99421 ttttcgtaca cttgcggaga attcttggaa ttacggattt tttgatgagg aggatcggct
    99481 aacaagtcaa gtcatggcga ccccttttcc agtgaatttt tacggacaag agtacctaat
    99541 ggccggcatt ggctatgttg cttcttatcc agaagcaagg ggacaaggcg ggatcaatca
    99601 gatcatggaa aagatccttg aagattgccg tgatcgtaaa gtaagcttat cttatctggc
    99661 gccattctcc tatcccttct atcggcgcta tggctatgaa caatcatttg ataaaatcag
    99721 ttatcaacta aacagtcgtg atgtgccgtt tatcaaaaaa aaatctggaa aaataaagcg
    99781 tatggatttt gaagatgcaa aagctgcaat cagaagaatt tatgaacaga tgccggaaaa
    99841 ccaacgagct ggtctgaagc gcgaagactg gtggtatacg tataaattca agcaaaaagg
    99901 caattaccag tttgctttgc attttgatga taatgaggaa gcaacgggat atatcgttta
    99961 tcagcttgca acgtcttcct ttattattgc ggagtgggga tttttggatc atgatgcttt
   100021 ttgcagcctt gttcgcttcg taagttctca caatggtgct tttgaaacat ttgaatattc
   100081 atgcggctac ggcggtaatg atcaaaatta tctattagaa aatccatttg cttctgtaat
   100141 gatcacacct tatatgatgg cgaggatcgt agatatttct ttgtttttgg aaaattatcc
   100201 atttaaaaag agacaagctg catttgccct acaaatagaa gaagatcatt atgcgaaatg
   100261 gaatgaagga atcgtggaag taacaatcga aaatggaaaa aatcatctct caaaagtaga
   100321 acaaacaaaa ctcccaatcg ttcgaggaag tatccaacat atcacgcagc tattattagg
   100381 gtatcgtaaa gtggaagagt tggtattcca agaaagaata caggtgacaa aagaatatga
   100441 agaaacgtta agctcaatct tgccacagca acagccaatt cttaatgact atttttgata
   100501 aaaaacgggt gatgacaata tttttgtcac cacccttttg tttttcattt ggcatttgaa
   100561 ggaaaatgtt aaagtaaatc ctcttttttc gtaaatttga attttttgtt ttcttttgtt
   100621 ttagggtttt cttttttgtg gtcttggatt gcttctttcg taatcttttc ccgatttttt
   100681 ttagatgaat ctaagcgttc tgcgtatact ttttcttttg gcttatcatt cattggaaag
   100741 gacctcccta cattatttca ttctacctct agtttatcat ctgttaagga ctagtggaaa
   100801 cgttttgcct aacttataag ctgatttttt tagcagataa gcttgcaagt aaaaaacaaa
   100861 caagctacaa ttgatttatt gaaattgttc ctgtagctca gtaggataga gcaatcgcct
   100921 cctaagcgat aggtcgctgg ttcaattcca gtcaggaacg tacaaataac ccctgtatcc
   100981 tttgtgatac aggggtttgt tttgtgtttg tgccaaaaat gtgccaaact agttatcatt
   101041 tttatataaa ctatcgaaca cagcattgat tttttcttta tcctgatctt caagctctcg
   101101 aacaatatga agataagtag acat
//
LOCUS       DACGEU010000002        68274 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.002, whole genome shotgun sequence.
ACCESSION   DACGEU010000002 DACGEU010000000
VERSION     DACGEU010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 68274)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68274)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68274
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.002"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            28..909
                     /locus_tag="IXR40_000104"
     CDS             28..909
                     /locus_tag="IXR40_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4359984.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            922..2532
                     /locus_tag="IXR40_000105"
     CDS             922..2532
                     /locus_tag="IXR40_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HAQ4359985.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(2609..3268)
                     /locus_tag="IXR40_000106"
     CDS             complement(2609..3268)
                     /locus_tag="IXR40_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HAQ4359986.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(3551..4216)
                     /locus_tag="IXR40_000107"
     CDS             complement(3551..4216)
                     /locus_tag="IXR40_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4359987.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
     gene            complement(4363..4968)
                     /gene="dhaL"
                     /locus_tag="IXR40_000108"
     CDS             complement(4363..4968)
                     /gene="dhaL"
                     /locus_tag="IXR40_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
                     /protein_id="HAQ4359988.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(4996..5979)
                     /gene="dhaK"
                     /locus_tag="IXR40_000109"
     CDS             complement(4996..5979)
                     /gene="dhaK"
                     /locus_tag="IXR40_000109"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HAQ4359989.1"
                     /translation="MKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRVVAKNQKAEQ
                     VGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEADSGKGVLLIV
                     KNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAGTVLVHKIVG
                     DAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDEIEYGVGIHG
                     EPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQFVFMNDVLA
                     LLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTISW"
     gene            complement(5981..6376)
                     /gene="dhaM"
                     /locus_tag="IXR40_000110"
     CDS             complement(5981..6376)
                     /gene="dhaM"
                     /locus_tag="IXR40_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HAQ4359990.1"
                     /translation="MKKSILLISHSQKVTDGIKEMIEQMQKSEEVQIFSLGGINGEIG
                     SDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEEEQQQRYHLVDAPLVEGA
                     FAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            6530..6850
                     /locus_tag="IXR40_000111"
     CDS             6530..6850
                     /locus_tag="IXR40_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HAQ4359991.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            complement(6962..7831)
                     /locus_tag="IXR40_000112"
     CDS             complement(6962..7831)
                     /locus_tag="IXR40_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAQ4359992.1"
                     /translation="MGKVMKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTI
                     SSSGAENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELE
                     EALEAAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQ
                     QAKEFNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAAS
                     FQRIKDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGV
                     LVAAAYGIIRKKK"
     gene            complement(7927..9231)
                     /locus_tag="IXR40_000113"
     CDS             complement(7927..9231)
                     /locus_tag="IXR40_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAQ4359993.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEYTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            complement(9228..9737)
                     /locus_tag="IXR40_000114"
     CDS             complement(9228..9737)
                     /locus_tag="IXR40_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4359994.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            complement(9912..12047)
                     /locus_tag="IXR40_000115"
     CDS             complement(9912..12047)
                     /locus_tag="IXR40_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAQ4359995.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(12130..13785)
                     /locus_tag="IXR40_000116"
     CDS             complement(12130..13785)
                     /locus_tag="IXR40_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAQ4359996.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(13787..14101)
                     /locus_tag="IXR40_000117"
     CDS             complement(13787..14101)
                     /locus_tag="IXR40_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HAQ4359997.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            14271..14531
                     /locus_tag="IXR40_000118"
     CDS             14271..14531
                     /locus_tag="IXR40_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HAQ4359998.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            14545..14859
                     /locus_tag="IXR40_000119"
     CDS             14545..14859
                     /locus_tag="IXR40_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur reduction protein DsrE"
                     /protein_id="HAQ4359999.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(15589..16143)
                     /locus_tag="IXR40_000120"
     CDS             complement(15589..16143)
                     /locus_tag="IXR40_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HAQ4360000.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(16269..18198)
                     /locus_tag="IXR40_000121"
                     /pseudo
     CDS             complement(16269..18198)
                     /locus_tag="IXR40_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
     gene            complement(18504..19220)
                     /locus_tag="IXR40_000122"
     CDS             complement(18504..19220)
                     /locus_tag="IXR40_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HAQ4360001.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(19221..21044)
                     /gene="glpO"
                     /locus_tag="IXR40_000123"
     CDS             complement(19221..21044)
                     /gene="glpO"
                     /locus_tag="IXR40_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HAQ4360002.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(21058..22554)
                     /gene="glpK"
                     /locus_tag="IXR40_000124"
     CDS             complement(21058..22554)
                     /gene="glpK"
                     /locus_tag="IXR40_000124"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HAQ4360003.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(22690..24150)
                     /locus_tag="IXR40_000125"
     CDS             complement(22690..24150)
                     /locus_tag="IXR40_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAQ4360004.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(24140..25435)
                     /locus_tag="IXR40_000126"
     CDS             complement(24140..25435)
                     /locus_tag="IXR40_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAQ4360005.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(25767..26444)
                     /locus_tag="IXR40_000127"
     CDS             complement(25767..26444)
                     /locus_tag="IXR40_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HAQ4360006.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(26474..27565)
                     /locus_tag="IXR40_000128"
     CDS             complement(26474..27565)
                     /locus_tag="IXR40_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HAQ4360007.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEEAYKELYLPSPLYNFLKARYQ"
     gene            complement(27666..28100)
                     /locus_tag="IXR40_000129"
     CDS             complement(27666..28100)
                     /locus_tag="IXR40_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAQ4360008.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(28684..30141)
                     /gene="ascB"
                     /locus_tag="IXR40_000130"
     CDS             complement(28684..30141)
                     /gene="ascB"
                     /locus_tag="IXR40_000130"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HAQ4360009.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENW
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIKDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(30138..32033)
                     /locus_tag="IXR40_000131"
     CDS             complement(30138..32033)
                     /locus_tag="IXR40_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4360010.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPIILLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSSVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(32091..33866)
                     /locus_tag="IXR40_000132"
     CDS             complement(32091..33866)
                     /locus_tag="IXR40_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAQ4360011.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARFPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(33916..35412)
                     /locus_tag="IXR40_000133"
     CDS             complement(33916..35412)
                     /locus_tag="IXR40_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAQ4360012.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     VIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRTWKEEDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(35606..37228)
                     /locus_tag="IXR40_000134"
     CDS             complement(35606..37228)
                     /locus_tag="IXR40_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HAQ4360013.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESIKAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTIPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(37556..38869)
                     /locus_tag="IXR40_000135"
     CDS             complement(37556..38869)
                     /locus_tag="IXR40_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HAQ4360014.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCVLMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLFGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFVGFMWILNVK"
     gene            complement(39114..39338)
                     /locus_tag="IXR40_000136"
     CDS             complement(39114..39338)
                     /locus_tag="IXR40_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360015.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(39358..39726)
                     /locus_tag="IXR40_000137"
     CDS             complement(39358..39726)
                     /locus_tag="IXR40_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HAQ4360016.1"
                     /translation="MIQKTRVMLYVNDVEMICRFFVEKIGAEISETIELPEEFKSIVL
                     SISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETIYENMEEPGEITDNNGILT
                     FNFSDPEGNYFVIGKAESSD"
     gene            complement(39922..40632)
                     /locus_tag="IXR40_000138"
     CDS             complement(39922..40632)
                     /locus_tag="IXR40_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360017.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGGESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(40650..41147)
                     /locus_tag="IXR40_000139"
     CDS             complement(40650..41147)
                     /locus_tag="IXR40_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4360018.1"
                     /translation="MTPSDVDLLQQISIETFTDTFGKDNSPEHLADYLTQAYALEKLT
                     EELKDKETDFFLVSIDQEPAGYLKLNTGTSQSEEMADHFLEIERIYVRKKFKHQGIGT
                     FLLDTAIEKAKEKQKTAIWLGVWEHNDVALAFYRKKGFIKYSEHVFYMGDDPQTDYLF
                     IKQLF"
     gene            complement(41184..41636)
                     /locus_tag="IXR40_000140"
     CDS             complement(41184..41636)
                     /locus_tag="IXR40_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003331879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAQ4360019.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(41771..42376)
                     /locus_tag="IXR40_000141"
     CDS             complement(41771..42376)
                     /locus_tag="IXR40_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HAQ4360020.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(42826..43446)
                     /locus_tag="IXR40_000142"
     CDS             complement(42826..43446)
                     /locus_tag="IXR40_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAQ4360021.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(43448..44317)
                     /locus_tag="IXR40_000143"
     CDS             complement(43448..44317)
                     /locus_tag="IXR40_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase family
                     protein"
                     /protein_id="HAQ4360022.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(44340..44747)
                     /locus_tag="IXR40_000144"
     CDS             complement(44340..44747)
                     /locus_tag="IXR40_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HAQ4360023.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDKHKLAKLYEQVGLKFSELYVNDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(44766..46055)
                     /locus_tag="IXR40_000145"
     CDS             complement(44766..46055)
                     /locus_tag="IXR40_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4360024.1"
                     /translation="MGVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     VLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFNNATATDVDTVAAALLYAWILSPVLKAF"
     gene            complement(46082..46384)
                     /locus_tag="IXR40_000146"
     CDS             complement(46082..46384)
                     /locus_tag="IXR40_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAQ4360025.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(46409..48502)
                     /locus_tag="IXR40_000147"
     CDS             complement(46409..48502)
                     /locus_tag="IXR40_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAQ4360026.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLVEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            complement(48991..49755)
                     /locus_tag="IXR40_000148"
     CDS             complement(48991..49755)
                     /locus_tag="IXR40_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HAQ4360027.1"
                     /translation="MKKINYLAIILLVGLCLFALPTQGFAVAGGHGGGTSSGRSSGRG
                     SFGGRSYGGSYFGSRSYGRDSYGYYGPGTGPSSYEQTGFLALAVLSVGGVSAFSIVKN
                     KRQKKRLKAEILSRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFA
                     EHQKVLQKNKADGVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLI
                     SGSKTQRQYFSQIWYFDFSEKEKRWQADFIQPIMLD"
     gene            complement(49866..50735)
                     /gene="mdcB"
                     /locus_tag="IXR40_000149"
     CDS             complement(49866..50735)
                     /gene="mdcB"
                     /locus_tag="IXR40_000149"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
                     /protein_id="HAQ4360028.1"
                     /translation="MINDERKKAVTQQLAALVEEALIAEVTLSPKPGLVDALDAGAHS
                     DMDYALFLKSAKTLTPFFEEMAQIAWHHAIDQELRERIAEIGRKAEKAMLIATNGINT
                     HKGAIWAMGLLISVIAQKISMEQPFSLSKILDDVSKLAAFPDTKYRHKKTTHGHRVKQ
                     KYGVNGAYEEAILGYPHIRLAIQAAKELDNDSYVQKQMHMLLVLMSSLDDTCVLHRSD
                     QKTLVEMQKLAHAASQSALPNRPFTALLHFCQENQISPGGSADLLSASLFMLKIEELW
                     TADTYICPMLLND"
     gene            complement(50760..51836)
                     /locus_tag="IXR40_000150"
     CDS             complement(50760..51836)
                     /locus_tag="IXR40_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HAQ4360029.1"
                     /translation="MFENKKIKINVSDFQKVSAVTAVMMQTILSFALANSHSATNTAF
                     LGTFYVIVKYTAPMFIFAIVYNMVKTSQHLSYWEFLKEKFFELVVPYLLWTTAYLWLF
                     PAVQQQTPYTDTASFLLKYVTGDGAPHLWYTVMMLQIQLFMPFFVWLGYKVFANKKYV
                     WPVLIGSTILYVAWYLFYQTQVLTGPYHDSWYLLDRFVASFMIYGVAAFVYHEKVYQY
                     LDRVRYLFLPVALVIAFFSVRSLLAHPGDLSFANAPYLNTIQSLYSLVIIFAVFIGAS
                     KMIVNDSPKLPLFKWLSVYAYRTYLANVFVFQVLLLLFKDSWLQLPSGVMILVAYLMT
                     ASCAFALSWLLHIIWVAIKKGFSK"
     gene            complement(51860..52453)
                     /locus_tag="IXR40_000151"
     CDS             complement(51860..52453)
                     /locus_tag="IXR40_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase holo-ACP synthase"
                     /protein_id="HAQ4360030.1"
                     /translation="MIQAHDIVLFDKHEIEGFTLPEWVVLTEKMFGTVRRASTDHAEI
                     LPIGLRGPARNQRWSTEISKHAVKQVIHPWDIIEQESYRQEKIMDYPVYQQFHAARNI
                     LSGCKWGIGGSLGFELSTGIPAVKETSDFDLLLYANSPIELPIQVIQSHPAFFEQFDT
                     QVVTRQGGFSLKEYLREPEKKILLKTVEGPKLTKELW"
     gene            complement(52457..54133)
                     /gene="mdcD"
                     /locus_tag="IXR40_000152"
     CDS             complement(52457..54133)
                     /gene="mdcD"
                     /locus_tag="IXR40_000152"
                     /EC_number="4.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-independent malonate decarboxylase
                     subunit beta"
                     /protein_id="HAQ4360031.1"
                     /translation="MKNSFVELNARERVNALLDNGRELIDPFDQIIAPSLPAQGIVPE
                     SDDGIVVSRGTINGKQAVVIAMEGKFQGGGIGEVSGAKIVAALEHVLEENKKGNEIFP
                     VIVLDTGGVRLQEANYGLLSISEIGNVIIALKQYVPVIGLIPGRVGSFGGMSITSALM
                     SYLIATKKARVGLNGPEVIEQEAGVREFDSSDKDLIWNTLGSRQRVESKIIDELVTDS
                     VEAIKAAVIAAMDERKDTHRSESSAFYLSLLDSLDLSKPMAIDDYNEAIANHQAKSID
                     LPEVAEGNEPAAASVGYDWFAALTGMKNPTSSISTVYYGKSSKFIEEAIVTSIVPDPK
                     NPMYRVRNGEVGLVEGFRMGQILDHVYEEDKDKKVKRPIIVVIDVPSQAYGYNEELIG
                     IHVALANSAAAYAKLRQAGHPVIGLIAGNAISGAFLAHGLQSSRLIALNNKEITVQAM
                     SKESAARVTKRSVAEIEAAAEKVPAIAYDINNYTKLGAIYHFLEDITDQAASEQNVSK
                     VIEAINEAIQDVRNTNDTMLTNRYTNETAKTFGRVETNKVRAKMDEEWDA"
     gene            complement(54123..54422)
                     /locus_tag="IXR40_000153"
     CDS             complement(54123..54422)
                     /locus_tag="IXR40_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit delta"
                     /protein_id="HAQ4360032.1"
                     /translation="MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKTESTVKI
                     CTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK"
     gene            complement(54524..56170)
                     /gene="mdcA"
                     /locus_tag="IXR40_000154"
     CDS             complement(54524..56170)
                     /gene="mdcA"
                     /locus_tag="IXR40_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit alpha"
                     /protein_id="HAQ4360033.1"
                     /translation="MEKPNRNWASKREKKAQRLEKISNLLNGKYVETEKIVEVMEKLI
                     APGDKVVLEGDNQKQASFLSESLEKVDAEKVNDLHLIMSSISRPEHLNIFEKGIASKI
                     DFSYAGAQSLRVAQMIEDGTMKLGDIHTYLELYGRLFIDLIPNVVLVAADKADKDGNL
                     YTGFNTEETPTIIEAAAFKDGIVIVQVNEVVDSLPRVDIPGDWVDVVVKADKPYQLEA
                     LFTRDPQNITELQILMAMMAIKGIYAEHGVQSLNHGIGFNTAAIELLLPTYGESLGLK
                     GKIAKNWVLNPHPTMIPAIESGWVESIHSFGGEVGMEKYIAARPDVFFVGKDGTMRSN
                     RTLSQAAGQYAIDMFIGSTLQLDYEGNSSTVTKGRLSGFGGAPNMGHNPGGRRHSTPA
                     WQSLRDNDDPLGKGQKLVVQMVETYGSNKKPVFVEELDALAVQKQAGLANAPVMIYSE
                     DTTHIVTEEGIAYLYKAKTKEERQAAIAAIGGVTPLGMTSTKESLDSLRAAGIVKLPE
                     DLGIKRSEAKRSLLAAQTIDDLIEWSDGLYEPPMKFRTWS"
     gene            complement(56177..57088)
                     /locus_tag="IXR40_000155"
     CDS             complement(56177..57088)
                     /locus_tag="IXR40_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HAQ4360034.1"
                     /translation="MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENY
                     QDTVFIQLALLTKAVFYLDEMEKNGIQPDIAAGHSIGAFCAAVACRSLRFENAAELVY
                     HRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSI
                     EGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKN
                     TDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKF
                     GVDKGIRTINLDQHGIDDATFLYQKWR"
     gene            57208..58065
                     /locus_tag="IXR40_000156"
     CDS             57208..58065
                     /locus_tag="IXR40_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAQ4360035.1"
                     /translation="MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELG
                     VPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASV
                     SIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAI
                     PKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATL
                     RSIVKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAK
                     TMREFYLGK"
     gene            complement(58252..58614)
                     /locus_tag="IXR40_000157"
     CDS             complement(58252..58614)
                     /locus_tag="IXR40_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360036.1"
                     /translation="MLTKKELIDHINETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVL
                     MSVPEEKIYDDASDHRIINILDLKVDPELGGILRGKEGYFPAYHMNKEHWISIDLRKI
                     EKLDELADLIDGSFKSTQ"
     gene            58960..60399
                     /locus_tag="IXR40_000158"
     CDS             58960..60399
                     /locus_tag="IXR40_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAQ4360037.1"
                     /translation="MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIGTTER
                     TIFSDLQSIRSQLPEGWDIISDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLF
                     TKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDLQIDLTKYTACILGKERAIRTFY
                     HRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELAVETEEIFGTCWFFINTIRIKA
                     NCRLDSSIHTNSTLSSLYDSALKKLYLTEGIYLKDTELSFASFCFLESWNYNNNYGQE
                     TARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLILKYHESPILIEALDR
                     QYHRFLETYDQQYAHLYQQKENLLNDLKKEIEINEPNYFLQLLSLLIQQTIFSIKPNL
                     FNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELTDLSTISFEKTDILISNFPLDS
                     LDIPIVYISSIPTKNELNRLTELTFKTFL"
     gene            complement(60406..62958)
                     /locus_tag="IXR40_000159"
     CDS             complement(60406..62958)
                     /locus_tag="IXR40_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HAQ4360038.1"
                     /translation="MNWYRLTVEDVLKNYQTSTEGLSQEERQKRLTDQGYNEIKARQQ
                     TKRWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEE
                     SLNGLKQLMGQEAIVLSNGMQEKIPAKELVKGDVIVLRAGDVVPADIRLIEAHDLLVE
                     ESILTGESEASEKSHAVLTEEESIGDQKNMGFSGTLVQSGSAVGVVVETGNTTEIGKI
                     NQALQSVEQQTTPLIKKINRLNKQIFQGILCLSLFLVIFTTFRYGMDWHILLSATIAL
                     VVSMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNE
                     MTVVDVAAKEEACVLSIMKNCQELKTKEEQKTENLSGNPTEVALIRHTETANLPLKKI
                     EAKIPFSSEYKYMATMHAEEKGAVIYVKGAPEVLFAKSTLSSAEQEAWSQTAAEFARK
                     GQRVLGFAYKKVDSKQELTHETLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKM
                     ITGDHKDTAKAIAEQIGLKHTAKVLEGIDLDLMSDEELIQQVPIVDVFARTTPEHKLR
                     IVKALQKNGEIVGMTGDGVNDAPALKRSDVGIAMGIKGSEVSKQAADMVLGDDNFHTI
                     AKAVKEGRRILDNLQKTINFFLPTALAQGLILIWALMLNRPLPLSPVQILWVNMVTTI
                     TLSYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVSLLIMVPAYLLAMQFEGQS
                     LQQTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKALFLSLGILALLQGMVIFLPV
                     GQQLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREYSR"
     gene            complement(63072..64403)
                     /locus_tag="IXR40_000160"
     CDS             complement(63072..64403)
                     /locus_tag="IXR40_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAQ4360039.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRAMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKENFGQIDELLPFGFAGMVVSFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKKAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQGGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFAGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            complement(64369..65847)
                     /locus_tag="IXR40_000161"
     CDS             complement(64369..65847)
                     /locus_tag="IXR40_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAQ4360040.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLENPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            complement(66152..67987)
                     /gene="tdc"
                     /locus_tag="IXR40_000162"
     CDS             complement(66152..67987)
                     /gene="tdc"
                     /locus_tag="IXR40_000162"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HAQ4360041.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEKVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     GQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKKIAKAMEKKLNEIIQ"
BASE COUNT        19422 a        14569 c        11676 g        22607 t
ORIGIN      
        1 atttttagaa aaaggagtgg ggtttttatg gcagaaatcg tcaaagtcac acatttgaaa
       61 aagagctttg gtcgtttcga agctttaaaa gatgtctctt tcaccgtaca ttcaggtgaa
      121 gtcgttggat ttatcggacc aaatggttct ggaaaatcca cgacgattcg gacactttta
      181 gggattataa aaaaagacgg cggaacggca acgatttttg ggcaagatgt atgggaagat
      241 agtttatcta tccatgaacg tctttcttat gttccaggcg atatctcttt gtggggaaat
      301 ttgactggag gagcgatcat cgatctcttc atgaagcttc atggaaaagg gagtgctcaa
      361 aaaaaagatg aactgattca acgtttctct cttgatccta agaaaaaagc aaaaaactat
      421 tcaaaaggaa atcgccaaaa agtgggcttg attgctgctt tggctgttga ttcggatctc
      481 tatttatttg atgagcctac ttctggttta gatcctttga tggaaacgat tttccaagaa
      541 gaagttgaaa aattgaaaga acagggcaaa tccatcctac tttcttctca tattctcagt
      601 gaagtcgagc gactagcgga taaagtcgtg atcatacgcg aaggaacact cgatgaagaa
      661 ggaacactcg atgaattgcg tcatttgact cgttcgacca tcactataga aacagaagca
      721 gagaatagtc acttagcaca attgaacggt gtccatgact ttgtgcaaaa aggtcacctc
      781 gctcaatttg ctgctgataa cgaagctttc gatgtgattt tagctgaagc gtccaaatta
      841 ggtgtgaaaa aatttgaatc tattccaccg actcttgagg atttattcat gagacattat
      901 gaaggatgag gaggaagcga aatgactgat aaattttcac gctggtccac ccttttttct
      961 caaaacctta gccgtgactg gaaaaagatc ctgatatggc tagtcggtgt cactgctttt
     1021 tctggtggtt ttgtccctgc gtttgaagaa ttgacttccg gacaaggatt agctggatta
     1081 tacgaaacct tgcaaaaccc ggcaatgatt gcaatggtcg gaccaactcc agcttcgaat
     1141 gctgctgagt atactttagg agcgatgtat gcaaatgaaa tgttgctttt ttgcagtttg
     1201 tttgctgctg tgatctctgt tttacacgtg gtgagccaaa cgagaaaaaa agaagaactt
     1261 ggtctgattg aacttattcg ttcctttcga gtcggacgtc aagcaaactc tttagctgtc
     1321 atcgctgaaa gtattctgat caatttgctt ttagcaatat cgatcagctg tacgatgatt
     1381 tttttccaag cggattcgat cactgcagaa ggtgcttggc tttttgggct atctgtaggt
     1441 agtatgggga ttttggggag tgccgttgca ctgtttgctg cacaactgat gccaagttca
     1501 gccagttcga atggtctgtc tttagcgttt ttaggtggac tttaccttct acgagcaata
     1561 acagatgtag ctgattcctc cctttcgatg tggaatcctt taggctggtc ttatttgacc
     1621 tatccattta caactaacaa ctggattcct ttgctttatt tgtttttgtt cagtctaatc
     1681 ttgataatca gttcatttgt tttagaggaa catcgagatt tgaacaccgg ctatatcccc
     1741 gaacgtgaag gaaaaccgta tgctaaacgt tctcttttat ccttgcgtgg tttattattc
     1801 tatctaaata aagggatgac aatcagttgg cttatcactt ttggtttgat gggggcggca
     1861 tacggctcta tctacgggaa tatgcaacag tttttagaaa gtaacgactt aatgaaacag
     1921 atgtttatcc aatctggcgt ctcaattgaa aaaaacttta caagcacgat catggtagtc
     1981 ttgatttgtc tagctgctat tttaccaatt gctagcatca atcgtttatt tacagaagaa
     2041 acccacggac gtatgaatca gctgttcgca acaaaaattt ctaggaacca actttattgg
     2101 accaatatgt tactagctat tctatttgct atattggcaa tcctgattag ttctggtgca
     2161 ctagggcttt ctgctttggc ttcgatgaag gatgcgaaag acatggatct attgatgttt
     2221 cttaaagccg ggttcaattt cctgcctgcc gttttagtgt ttatcggaat tagtggcttt
     2281 ctattcggat ggcttcctcg aatcggtaaa cttgcttata tctacttagc ttactccttt
     2341 gcactcaatt actttggcgg aattttggat ttaccagaat ggttttccaa aacagctgtc
     2401 cctagctggg ttccacggat gccaaacgat tcttttgatc tttccgtgtt ccttacgtta
     2461 tcatgtatca gccttgcact gttcgtcctt ggttctattg gttataggcg aagagactta
     2521 ctagaaggat aataaaaaag catgtacaat ttcatgctag cctccaaatc tgggtcaaaa
     2581 atccaacatt tggaggtcat ttttttattt acaagtcttc taactgctct ttatcaatga
     2641 tccagacttc tcgattcttt ctttttacat aaccattctc ctctaataat ttaaattttc
     2701 tagataaagt ttcgggggtc gtaccgataa atgcagcaag ttctttcatt ttcattggca
     2761 ggaaaaagtg atccttccct gtcgctttag ctaagtcaag cagatagaca gcgactcgtt
     2821 cttctacttt ttccatcatc aaaaaagttg tctgctgctg tacttttgtt aatttctcaa
     2881 cgttgattgc taaaagtttc agactaaggg cgggataatg cagtaagagt tccgagaaat
     2941 ctttttgtct caatatgcaa atttccgttt tttctagtgc ttcgccaaat aaagactcat
     3001 ttggaacgcc tagcaactgg ctctctccct catatccgcc cggctctatt actcgtaaaa
     3061 gctgttcctt tccgctagca gataattgat acactttcat actgccggag gccacgatca
     3121 ctaattgagg ttctccattc ggcgcaagaa tctgttctcc tttttccaca tagtgatgtt
     3181 tgacaagtgc gtgtactttt tcttgatctt gctgtactaa gtgattgaac aaaggaacaa
     3241 atgaaacaca taaatgatca tgactcataa tctctcctcc ttctaaacag ctatttctaa
     3301 taaagaaaca taacttccct tattccaact gataattttc ttttatcata gcataaacgt
     3361 caagcgaacc agataccagc aaatagagtg gatttctttt tgtcccttgc tttattttcc
     3421 ttcttttgag accttaagta attgattcct atcaattttt taaatattta ctttttgaat
     3481 aatcaaaaac aaaccttcac tcgcaagccg agagtaaggt ttgtttttcg cattgcttat
     3541 ttcgtgttgt ctattgaaat ttttccgcac ctagcttttg atatagtggt gctagttctt
     3601 gtaaggtttc agcggttatt tgctcaacgt gttcgatttc ttgcggatag aagaatagtt
     3661 tacccatttg aaaggttcgg tctctcatcg cttttttcaa ctcttcttgt ttctttgtat
     3721 cggacaaata gtcagacaaa gctaagtggt cgtcaagttc atgttctggt tgcggccata
     3781 tgtaataatc cttgatatcg actgttttgc tccactcttt cagtatcgca agcaactggt
     3841 tatacgctgc aatgctacca tatcgttctt cgcttttata atgttggtac atcaaataga
     3901 tttggtattg tttttgattc aacaaaactg ctagacaggc attctcgtct tgacgagatt
     3961 cgcttcggta cgcgctccaa aaatgactgc gtaaattcca gccattcgtc cagctttcga
     4021 ttttaggttt gctcatgccg tacatatcag gcaaaagtgc agctgtctgg agctgaatct
     4081 ctttccattt ttgccagtgt tctttatatt ctttcttgat ttgttcaatc ttatctgttg
     4141 gatggctctc tttgagctgt ttgaatgcgt agattggtcg atcaaacaac tgataatctg
     4201 attttccaag ttccattgtt tcgcctcttt ccgttatctt ttgtattcta cctgaatttt
     4261 gcgatatgga caaatagagg ttgtgaaaaa gctgttctgc atcaagtcat aagaacagcc
     4321 aaacaaaaaa ctgcgatgag catcaccgca gttttattga acttaaggtt gattgatcac
     4381 atctaaaagc gttgaaaata aaatggcact agaagcagct cctgggtcga tatgtccgat
     4441 tgcacgctct cctagatagg aagctcgtcc ttttttagct accaagactt tggtgtgttc
     4501 ttttgcctgg tcaatgattt cttttgttaa attccctgcc ttcaatgcct ctgtgactgg
     4561 cagccaaaca tctaacatcg ttttatcgtc agcttctgcc tttcctcggc tttgaatacc
     4621 cgctgttccc tgctcgatca cttcgcctaa tttttcttga gaatcaatag aatcgacctc
     4681 ttttgtcgct ttcatcatgt tcatgaatgc agatccgtat aacggaccag aagccccacc
     4741 gactttcgat atcatcgcca tagagaatac tttgaatgta tcgctgattg tttcaggatg
     4801 atcggcttga aaagcttctt cataagctga aacccctctt cccatgttat ttccatggtc
     4861 tccatcgcca atcggggtat ctagatcact gagatattgt ttgttctgat tgattgcctc
     4921 tgcaaattgc gtgagccatt cttggatttc ttgaacggtt agtttcatat tatcaccctt
     4981 ttatcttgag attttttacc atgaaatcgt ctgtacattg ctttctaaag aatctttcca
     5041 ttgtgtctcc gtcaagtcga tcagtgttag agaaagacct tgcatatcta gtgaggtcat
     5101 aaaattaccg acttttcgga aaactacatt gacgcctctt tcttccaaca gagctaaaac
     5161 atcattcatg aacacgaact gttccatcaa aggcgtcccg cccattccgt tgactagtac
     5221 acctgcttct tttggtaaat tcgagtaatc atctaaaatc ttagtaacaa gttcctttgc
     5281 cagtacttta gaaggctgca tcttttctcg acgatagcct ggctcaccgt ggataccaac
     5341 accatactcg atctcatctt ctcctagttc gaatcctggt ttccctactt ctggtacagt
     5401 tgctgctcga agcgctagac cgatcgtctt agttgcctgt acgacctttt ctcccagttc
     5461 tttcaactca gctagggaag caccgtttct tgctgcatcg cccacgattt tgtgtacaag
     5521 gacagtacct gcaactccgc gttttccagc agtatacgta ctattttcaa cggcgatatc
     5581 atcatctacg atcacacttt ctacttcaat atcgtccata gcagctaatt cctttgccat
     5641 atcgaagttc aatgcatccc ctgtataatt cttaacgatc agcaaaactc cttttccact
     5701 atcggcttcc ttaatagccg tctgaatctg atctggagtt ggagaagtaa acacatcacc
     5761 aagcaccgct gcacttaaca tcccttcccc tacaaacccg gcatgggatg gttcatgtcc
     5821 gcttcctcca ccagaaacca aaccaacttg ttccgctttc tgattcttgg ctacaacacg
     5881 ggaagattct acacgatgaa caagttctgg atagcttttt actaatcctt ccagcatttc
     5941 ttcgacaata ttgcttggat cattcatgat ttttttcaat ttattcccat cctttctttc
     6001 cggcattttg tgcttctgtt aagatttgct gagtatcatc tgttataccg gcagtgatgg
     6061 ctgctgcaaa agctccttcc actaaaggcg catccaccag atgataacgt tgctgctgct
     6121 cttcttccaa catgtctttt gccagttccg agttcaatac cgcgctaccg atatccgcaa
     6181 aaacaaaata actagctgca tcgcttgatt cattgactgc ttctacgatt ttcatcgggt
     6241 ctgatccgat ctcgccattt attccgccga gagaaaaaat ttgcacctct tcggattttt
     6301 gcatctgctc aatcatttct ttaataccat ctgttacttt ttgactatga gaaataagca
     6361 aaatactttt tttcacaaga atcttccttt cttttacata gttgctaacg attggtttcg
     6421 ctttcattaa tgaacaattc aagtatataa taaatttcta attttgggaa aatatgtgta
     6481 gtgcttcttg aagtttgtta tactttaatt aaaagagagg agtgatcgaa tgattacaac
     6541 aacaacgaac agtgtagagg gaaaagccgt agtagcttat aaagggatcg tttttggtga
     6601 ggtcattact gggatccatg catttaaaga cttggaggcg gggttgcgaa atatctttgg
     6661 cggccgctca aaaagctatg aaaacgaact aatgggtgca agagaagaag cacttgccga
     6721 aatggccgaa cgtgcaaaag cattaggagc tgatgcgatc attggcgtaa aaatggacta
     6781 tgaagtatta ggcagcgaca atggcatgct gatggtcaca tgtagtggaa cagctgtctc
     6841 cacgagataa gtaggggaca tctgttttaa taactaaaga gagatgggac atgtagtggc
     6901 actcaagaat tagatttttc agtctaactt cgaggtactc taccttccca tcctctcttt
     6961 tttatttctt tttgcggatg attccgtaag ctgctgcgac taacacaccc gcccctgcta
     7021 aggaataact gacagaagct gttttttcat ttgtttttgg caaagtctga cttgttgatt
     7081 tggatggctc tgtcgtttgc tgaactgttt ctgtcgtgct tccagaggtc actgattttt
     7141 ctcctgccga atgcaaaata tcttttattc gttggaaact agctgctaag tcagcttttt
     7201 ttgcttcaaa atcattagca actgtttgtg cttcgctgat ctttccgtgg attgcttgac
     7261 tggccgctgt gatatccgct tgagtttgac ttagctttcc agaagctgtt tgagcaacct
     7321 gatttaattg ctgattgaat tcttttgctt gttggatctt cccgtcaaga tctgtttgga
     7381 cagcttccgc ttttgctttc gcttcggcaa gctttttctc aagttgtgca cggtcatttc
     7441 ccactttatt tttaagatca gctaaatctt gatcgattgc tgcttggtct tctttcaatt
     7501 tgttttttgc agcttctaat gcttcttcga gttcttttct tttattttcc aagtcttgca
     7561 aatgatcgat ttggtcagaa gaggtagaac tatttattga tgtatcttct gaagatgaaa
     7621 tcgtttctcc tgaattatct gtcggtacat tggaagtcat ttctgtttcc gaggcaccgt
     7681 tttcagcacc agaagagctt atggttgttg aaggttctgt ttgagcaggt tcagaagttt
     7741 ccgcaaaagc tgtctgtccc aataagaaaa tactggaaac agcaattggc cagattaacg
     7801 gcttcattct ttttttcatc acttttccca tccttactac tttttaacta atttcttatt
     7861 ataagcaaaa atgtttggaa gaaccataaa cacaacaggc tgtttgtcta aaaaacggtg
     7921 catcttttat ttttttgtac gttccgggct tttccatgtc ccgcttccat aacctaaaat
     7981 cgttttgact gctggaatga aagtcgtcac gatcgttatc gcgttcacta tccagaacaa
     8041 aagcatatat agtggtgcga aaagaaggta tttcaatttt cttcgtcgat catctacaat
     8101 cagcgaagct agcaactgga aaaatcctgc gaccatttca aagcagatga acacaaaact
     8161 gaatgtaaaa gtaatataaa tctgttcgta gtttccttga tatacataat gcccgattaa
     8221 tccagcaaaa agaactacgg aaatacaaaa gaatattgac cagacaatac tcaatgtttg
     8281 atcaatgaag atgatcgttc ttccaatatg tttaaaagga tggagcatca cttttttgaa
     8341 attcgtcagc cagacttctg ttccaccttt tgcccaacgt tttctgtgtc gatatagcat
     8401 cttcaacgtc acaggtactt ccatgaaaaa gataatctca ggagcaaaaa cagataacca
     8461 gtcatttaac tgatgatccc aagcaatact gatgtcttct gtcgctcgat cttgtctgaa
     8521 tccgcccaca tcgatcaagg cttcttttcg atacatcgta tttgctccac tgtacgcata
     8581 aagaccaccg aaaacagctg actgtgttcg tttaatgatg cccacgatac ttgagaattc
     8641 aaccgtttga gattttgcaa tcaatttggt acgattttgg acatccatat ttgcagtgac
     8701 cgcagcaata tgtcttgcac cagggcgaat gaaataattc acatacctaa tcagtgcatc
     8761 tggctccggt accgtgtctg catcattgct taaaatcaat ttcccttttg caaaggcaag
     8821 tccgatatta aacgcgtggg cttttccttt atttttttcg atccgaacca cacgaagatt
     8881 agcgtatttt ttcatcagtc tagctaatat ttctggtgtt tggtccgttg aaccatcgtc
     8941 tgtcactaat acctcatagt tgtgataatt caatttcgtc atcaaatact cgattgtata
     9001 ttcgatcaca atttcttcat tatgggctgg caccatgatc gtgatgaacg gttcgacact
     9061 caagggaaca tctacccatt ctttttgctt atgtttgtat aaaaacacat aacaccagac
     9121 accaataaac catacaaatc cgcctaaaat cggataagaa acgagaaaaa aatacataat
     9181 agacaaacaa gtatctaaga ataaattacc tgtatgggtg attgagatca tttcagttcc
     9241 accccatttt ctttatacaa atctgcaatg aatgtcgtat ctagattttt ctcttcggag
     9301 acagaataaa aacggaccgt ttctctctct tcttttgttc caaaacgttc cgtatacact
     9361 tcttcaagta attcttgtct ttttttcaat ttttcatctt catattcaaa agatttattt
     9421 acttttttgt atagatttcg attgttccac ctagtcaata caaatgaggt aatcaggaaa
     9481 ctgaaaaaaa tcaatacaaa aaagccgatt aagaaataca gcattttctt ttctgataaa
     9541 aaagcgtaca aggaaaaatc cttggctctt tctggtctcg ttaatgggaa aaagacccat
     9601 ataaaaggaa gaacaacgat catccatcct aaaagagcca ctaacgtttg ccaaatcttt
     9661 aaccagtaat taccttttga aaaatactta tctttcacca aaattgatgc aacttcttct
     9721 cttgttactt ttttcatatc ctcacctcac gtttttttgt tacgacgtag gagtttacca
     9781 tacatttcat ttcttttcac ataaagtgtt cctaaatttt tcctaagaaa aagaacaaaa
     9841 catttctcat cagcaaatga aaaatatttt gttcttttta tcagttgttc tttttatttt
     9901 ttatctctta attatgttgc tctttccaat acgacaatgc ttttcattcc tctagatatc
     9961 gccgtgtaca tttgtctgcg tcttctttgc tcatctccat cgttttcaaa tggatataag
    10021 attacatgat caaattccag tccttttgct agactcaaag gaatgatttg gcagttttct
    10081 aatccatatg aatttttttt aatcgattct tgtagcgttt gggtttcctc ttctgtttgg
    10141 gtgataactg ccgctttttc tccttttaga gaaaccaaaa tctcagctag tattttcaac
    10201 aattcttcag aggatcgaaa agagcggtat tcgggttctt ttccttgcgg tcggatcgat
    10261 acgatgtcga tcttctcttg atccacagca taggttttga aaagctctgt gattgctccg
    10321 ctagaacggt aactatttct aagatcatac cgatggatcg gcagatggta gtcgtcgaaa
    10381 caacgcataa tatcagcaaa agtagtggaa gaattaaaga ttgcctgatt ctcgtcacct
    10441 actaaagtaa agtgagtttt tggaaataat tcgatcaata gacctaattg tgccagggta
    10501 taatcttgta cttcatcaat caatagatag cgaaatgctg gtacatttac cttttcaaca
    10561 agtaaatgac gaatagctaa tataatgact gcttcatcaa cagtacgtgt gggttgccaa
    10621 gcataagctg agccatatcg tttttcataa attctttcaa acaactgatg ctcatccacc
    10681 catgccattt cttcgatttg tctggttatt tttcgatatt ttttttgtaa aagtttcctt
    10741 gcataagcta caatactttg ttccgaatca tcagaaatca atttaccgaa taattccaac
    10801 tgcctatctt ctgtcaacga gagtacctga ttctgcacag caggactttt tgcttgtttc
    10861 aaaagatgat tcttccattc gctcatcagt gcctttttcg ttgcttgaag cctatcgatc
    10921 aatttaggat gagcaggaac tttctcatat attttttcga tcgttttttt agaaaggact
    10981 gtttttccat ttttagtaag tccacggata aaattcggat gatctaaaaa caaaggatct
    11041 gattgtttta gattatcgat aaactttttg ctacgcaaac gttctgtctg ctccgataca
    11101 ttttctcccg tgatacgttt gaaataagcc tcttcacctt ctatttcctc tgctgaaagc
    11161 tgtgaaacca gctgtatgat ggttagattc agtggatttc tttcacctaa tgatggtagg
    11221 acattcgaaa tatagtcgat aaaccgatga ttaggtgata gaatcagcaa gtcatcggat
    11281 gtcatcgtat ctcgatataa atagagcaga tacgcaatac gctgcatgat agcagaggtt
    11341 ttaccacttc ctgctacgcc atttaccaag atattttgac ttttcacatc ccgaatgatt
    11401 gtgttttgtt ccgattggat cgtagcagtg atagccttca tttcattggt ctcatcttgg
    11461 cctaagactt ctaataatac gtcatcttga atagctacag acgtatcaaa aaacttgacc
    11521 aaacgatctc tttccaaaag aaattgtcgt ctttctttaa taaccgtatc gattttattt
    11581 tgacgaaccg tataagaaga tggaccaatc atgttattgt aaaaaagttc ggcaattggt
    11641 gaacgccaat cataaacaag attttcatct gcatcatctg tgaaatttgc tgtaccgata
    11701 taaaaggatt cttttggctc attatccaga aagtctacaa cgacttttcc aaagtaggga
    11761 cttttcaata aacgttcgat ctttgctagc tgattttctg cgtttttctg tttgatattc
    11821 atctgatcga tttctctatt tttcatttca atcatcgaaa aagtatccag gttatctaag
    11881 taactgtcaa aattcaatcg aagctcgcca gccatttctt tcaacgactg gtttccttct
    11941 atttttgccg tatccatcga ttcccgcagt tcgttttttt tatcaattag cttttgatac
    12001 acgttcttca gatatgcttc ttctaactgt ttttgtgtgt tgaccataca cattctcctc
    12061 tttttttaaa gtggtggaac cgattagttt acctctttta agagtcgaat gcaagctttt
    12121 taacgagtat catttgttag gatatatcag ttcttcaggt cggacagttt gatataaaga
    12181 aaatgcacca tcaaggtttt ttacgtggta gccagactgc ttcaagattc tttccgctag
    12241 atagctacgt aatccgctat gacagctgac gatatattct tgttggctgt ctaattcatt
    12301 taatcggtcc cgaagttcat tcaaagggat atgtttggct tccttgaatt tgcccttttc
    12361 caattcttct gctgttcgca catctaataa aatttttcct tttgctagtt ctgtcggcaa
    12421 ttcatgccat tgtacggttt cactaagccc ttctgcaatg ttcattgctg catatcctag
    12481 catgtttact ggatctttgg ctgagccaaa tggcggtgca tacgtcaatt ctaattccgg
    12541 taaatcgaag atcgtcaaat gccctttgat tgctgttgct aaaatatcga tccgtttatc
    12601 cacacctttt gccccaacac cttgtgcacc ataaatctcg ccagtctctg gatggaagat
    12661 caacttcagt aaaatatctg ttgcttctgg ataatagctt gcatgatctt ttcctgatac
    12721 atgaatgact tcaaaagaca gttcgttttc tttggctgtt ctttcactta aaccggtgga
    12781 tgcggcagtc attccaaacg ttcgtataat tgctgttcca ataccgcctt gatttcttcg
    12841 agaaattccg gaaatcgtgt ccgcaacttg tctaccttga cgattggctg gtgaagcaag
    12901 agaaataagt gcatcttttc cagtgatttg ctgttttaca acgatagcat cccccaccgc
    12961 ataaatatca ggaatattcg tttgataacg ttcgtctact aggatacccc cgcgtatgcc
    13021 taattcgatt ccagcggtca ctgctagctg gttatcagga cgaacaccaa tggataaaat
    13081 aactaaatca gcagggatgg tacgcccatc atccagtcgc aatcgtttcc cgtggtcttc
    13141 aaatccagcg acagcatgag aagtaatcac ttctactcct tgatgagaca attctttttc
    13201 tataaaagct gccatttctt catccagtgt tggaagaata tgtggtgctt gttcgatcac
    13261 catgacttct aaacctcttc tttttaggtt ttctgccatt tccaatccga tgaatcctgc
    13321 accaacgatc acggcacgct ttggctgttt ttctaatgca tgcatcactt tatcgatatc
    13381 tggtacattt ctaatagaaa aaacattgtc ggcttctgtt atccctggaa tcgatggaac
    13441 aactggtttt gcaccaggag ataaaaccaa tgcatcgtac tgttcaatgt gtttttgacc
    13501 ctcatgtacg acttctaccg ttttgttttc gggaaagatg gctgtcactt catgatttgg
    13561 acgcacatct aaacaaaaac gagcggataa tgattctggc gtttggacaa gaagattttc
    13621 ccgttcactg atttctcccg aaagataata aggcaagccg caatttgcaa aagaaacata
    13681 cggtcctttt tcaaaaacaa cgatttctgc atcttccatt aatcggcgaa gccgtgtagc
    13741 agcagacatt ccacctgcta cacctccgac aataacgatt ttcatcttat ttccctccta
    13801 ctgttcgatc aaaccattga ttcatgccac cacgtacatt cactacatca taaccagatt
    13861 tctttaattc tttagctgct tgtttactcc tcatccctga ttgacaaatc acatagacgg
    13921 tcttttcttt gtctccatca tatctgttta tactttgtaa tggaacattt ttagctcctt
    13981 ttatatgccc gccccggtat tctgcaggtg ttctaacatc aagtaacgct ggattttcca
    14041 aaagcttttc ctttaattct gggactgtta tcgattttat tgattgaaat agcaaattca
    14101 ttttctgcac ctcatttaca tttttataaa tacctcatgg ggtatattaa acaggagctt
    14161 tattaatatg tcaaccagaa tgactcttca tttttttcac tactttttat atttgcataa
    14221 aataccgata aggggtatta tctaattata aaaatagagg agaatgtgtt atggagattg
    14281 ataataaaaa tatcctgaac cgtttgaaac gtacagaggg acaaattcgt ggtatccaaa
    14341 aaatgatcga agacgaaaaa gaatgtatgg atgtcatcac tcaattaagc gctgttcgtt
    14401 ctagtattga tcgcgtaatg ggcatgatcg ttgcagataa tctgaaaaat tgctttgaga
    14461 aacctgatag taatccagaa gaacaagcgg ctaaactaga acaagcgatc aagatgatta
    14521 ttaaaaagta aaggaatgat ttcaatgaaa gtcgttttcc atattgatga attagaaaaa
    14581 tggtcagaaa cagggaaaaa cgtaaaaaac ctgataaaag cttctccaga aacgacgatt
    14641 gtcgtatctg taaatggcat cgcgattacc ggttatctag actctgccaa tgcagaattc
    14701 ttagatttgc aaggagtcgt ttttcacgct tgcgccaatg ctatgcgtgc taatcatatt
    14761 tcagaaagtt ctttacctga acaagtaatc gttgtaccag caggtgtcct tgatttagtt
    14821 gaactgcaat cccaaggtta tgcttatatc aagccttagt cagtagaggt tgcgacagaa
    14881 gtgatcagct tcaagaaatt tcggcttatt tttcgaagaa gctacttctg gaaaaccgtg
    14941 aatcaaaggt tgtgaaaacg ctgtcctgca tcaagtaata agaacagcca aacaaaaata
    15001 gcttctcata tttttcgttt ggttgggctt attaccgcag atgcaagctt ttgaacaccg
    15061 tttaaggaag aggttgtgaa atcagcggtt tgacctaagt attagagaaa aaaacgggaa
    15121 aatagctcct catattttgc cgttttttga gctaataccg aaggtcagct gattgaacac
    15181 cgtttaagga agagattgtg aaaaagtcgc ttagtttcga gtattaagaa aaattttgtg
    15241 aaaatggatt tctacatttt tgcataaatt tggcttaata ccgagaaact ggcttttgaa
    15301 taccgtttaa ggaagaggtt gtaaaatcag cggtttgacc tgagtattag agaaacaaac
    15361 ggaaaaatag ctgctcatat tttgccgttt tttgagctaa taccgaaggt cagctgattg
    15421 aacaccgttt accaagaggt tgtgagccta ccatttaact ccgaatcaca agaaataatt
    15481 tcaaaaacaa cttctcctgt ttttggttcg gttggcttat tatcgagaag tagctactgg
    15541 gagtctattt atcaaaaaaa ggaatgcgac ataggtcaca cccctttttt attttctttg
    15601 aaacatcttt cggtactcga cagcatacaa gacaaaagat tgtaaaagac cgtaagtgat
    15661 gacggcaaaa atgactctca cccacagcgt tggtaattct gggaaaagca gcaaaaggat
    15721 catgccaaca tagatgacag cagtcgctac tttgccatac cacttcgctc cacttaattt
    15781 gatattttta gatagcccga ttaatccagc tacaaacata aagccttctt ttatcaagaa
    15841 tagaccaaac aacagccaaa gccacggtcg ataccatgcc atagacaaaa tcagaaaaag
    15901 ttgtgtcaat ttatctgcaa acggatcaag caccttccct aagtctgtta cctgattata
    15961 tctccgagca atgaccccgt ctagataatc agacaaacct gagacaacaa tgaccgctcc
    16021 tgctatataa aatgactgtc tcagcacaaa ataaagataa atcggcagca aaaaaatacg
    16081 gaatatcgat aaaagattcg gaatcgtttg tatttcttta cgccagtctg tgcttaattt
    16141 cattttatcg ccctacctcc tcagcactct tttcttttta ttttagctta cacggggaat
    16201 aaaaccaatg atttcactgt ttttattttt ctttacagac actgatatta tgagctaatt
    16261 tgagataatc acttgctgtt ttcatcgttt actcttcttt cttcctgtcg tttgcgcatt
    16321 tcttttacta gtactttatg agcttttttt gatcctcgct ctaggtcacg ctgccgttta
    16381 cgtgttttat aatcgataaa cagactgtct aaatcgtaac ctgtcgggta cagatcttct
    16441 gctgaacgca ccagacgaac acgctgacga ggcacgtgga ttattttttt gtctaaatat
    16501 acatcaatcg tatcttcacc tatatcttca taaactaacg cttctttttg gtattcattg
    16561 acaaatatcc gatcaccttt tgcaaagagc tgacgttctt ttttattctc cttcctattt
    16621 gtaactgctg tcttaggaag aaattctttt ttctgtgtcc gataggcttt ttccgccaag
    16681 taacgctctg cttgatggat caatttcatc gacatatcca ttttatgagc aatccacaaa
    16741 gcttggcttt ctcctgtttc ttccaacccg caactgatat ttaggacgaa gtgcttcccg
    16801 atcgaaagcc atagcagccg gcacaaaatc ttcatgatct ccggcgaatt tcttgatttc
    16861 tccataatgg gtcgtggcaa tgatcaatgc cccttgctca tacatagatt ccatgattgc
    16921 gatcgctagt gcagcccctt catttggctc tgttccactg ccaatctcat ctaaaagtac
    16981 caacgtattc ctttttatct ttttcaaaat agcagcgatg ttttgcatat gaccagaaaa
    17041 tgtactcaac gcattttcta aattttggtg gtcaccgaca tcgacgaaaa tctcatcaaa
    17101 gacagcaagc tctgtccctt cttttgccgg aacttgcata ccgaacatcg ccatcaaagt
    17161 caataaaccg actgtcttca acacgactgt tttgcctccg gcatttgctc cggtgataat
    17221 caagcctcga tagtctttac cgatttcaac atccaatggt accgcatgct caggtaaaaa
    17281 tggatgtctg ccttgcttga taatgatatg ttccgattta ttgattctag gtgtgcttcc
    17341 attgatttct cggctaaatt ttgcccgagc aaagatgata tctaacaccg tgatcgtttc
    17401 gatcaataaa tcgatcactt cttcgttttc tgcgatagca ccagtcaatg ccgccaggac
    17461 ttgatattct tcactgattt cttcagcttt taacaactga tagtgttcat tcaatttaga
    17521 aatcacagtt ggttcaataa aaaccgtcgt tcttttattt gattcatcga taatcgttcc
    17581 atctatttta tttttatagc tggctttgat aggaatcgta tagtattcgc ctttttgaac
    17641 aatcattgct tcttggatca tttctttgtt tttcggatga cgcaagaatt tcagtaattt
    17701 tgactggatt tctttttcga ttagttgtaa ttgtttgcgt actttacgca aattacgtga
    17761 cgcgtcgtca ctgactttat tattttttat tttctggtca atcaactctt ctacatttat
    17821 caaatcagga agatgtttgc tataagcaaa caacaagggt gtctggtatt gattcttatc
    17881 aaaaaacttt gtgatcatcc gactgcttct aagaaaatcc gcatattcga tcaaatcggt
    17941 tggctgcaga atcaaccctt ttttgacttg ttctgtcagt gcatcgatcc tcggcaaccc
    18001 cataaatgga acatgctgac tgctttctaa gatcaagcgt gcttctcttg tttcttcttg
    18061 acgatccaag acagtttgta ggtttgtcga gaccgtcata tcgctgattc gttttttgct
    18121 atagtttcca attgctcttg cttggatttc ctttttgatc cgatcaaatt gtaattgact
    18181 aatcatttcg ttgtccatat tctctccttt tcttgaagag atacctgtcc caaaataaat
    18241 aagggcctag agataaataa aaggatagaa cacagcttaa aaaagtcatg tcctatcctt
    18301 attagaatac aaagatattg ttttcctgac aggtaccgtt tcataagcac accaaataaa
    18361 ctttgtttat tggctattcg acttactgat tagataccag ctacactcac aaaacatacc
    18421 ccattcttct aggtcttatt tattttccac ttaactatag caagacacat tttggttgtc
    18481 aaactttagt atgttttata gatttacacc attaatgaat agacacctac cgcgataatt
    18541 gctccgatca ttggacctgc gattggtacc catgaatatg cccaatctga agttccttta
    18601 ttagctattg gcaataccgc atgtgctaat cgaggaccaa agtcccgagc agggttgatt
    18661 gcatatcctg ttggccctcc taatgaaaga ccgatggcta agatcaatcc acctacagcg
    18721 aatacgttcg ttccaggtgc aaattcgttt tgtccaaaag ctagcaaccc aagaactaat
    18781 acaaatgtac caattaattc tgtgatcaca tttgctggat aattccgtat agcaggacct
    18841 gttgcaaacg ttcctaaaat cgcgctttca tctttcgttg cattccaatg tggcaaataa
    18901 gaaagccaaa caagaatggc ccctgcaaaa gctcctaaaa cttgcgcaat gatgaaagga
    18961 acgacaagat tccaactaat tgcccctgtc atcgccatag ctagagagac tgcaggattc
    19021 aaatgagctg ggcccatgaa tccagaaata tagacagcca ttgttacagc gagtccccaa
    19081 ccaaatgcga tgacaatcca gccagaagcc tgtgctttac ttttgtttaa attcacagcc
    19141 gcacacacac catctccaag caaaactagg atcagtgtcc caataaactc ccccatgatt
    19201 tgagtcatat cactgttcat ttatttctcc ccctttagtt cccgcagatc tgattctgca
    19261 atcaatgctt ctaaacgttt agtctgttgc gccttctcct cttctgtcca ttcaaaatat
    19321 ccagcaattg catcgatcac aggttgcttg atctcatcaa gctgatctcg ttcaaacaac
    19381 agatgatttg tacgacgaat gagataatcg cctggggcca aaaccatttc ttcttctaaa
    19441 ccataacgta accgagctga ctcagcgaga ctcaaaccag gataaggtgc catttctttt
    19501 gctaattcaa agatacgtcg ggcattagtc ccgtaaaaat cagcgatata agtagcatct
    19561 tcttcctcta aaccggctgc tactccttct tttgctaatt ctgtcactgt ttcttctaat
    19621 ttagttggat cgaagtttcc acctgaaatc tgatattttt tagagtcgat ttctttcgtc
    19681 tctattccgt attcttcttt taataattgg cgtatcaatc gcaaagctcc ttctgccatc
    19741 ttacggtaat cggtgatttt cccaccagat aaagtcagca aaccatctgg ttctctttct
    19801 aaagaactac ctctggaaat cgtagaaggt gctttttcat cacggctgtt ttccaaatgg
    19861 ttcaacacgt cttctacttc agcacgagaa actttgtttt ccttatattc acttactgta
    19921 tcgacaactt tattgaagct cttgtctgaa atcgatccat tatctccacc attgtaatca
    19981 gaaccagaat taccaatcaa cagtggacga agtcctgccc agcttgcttc gatatcattc
    20041 aatgtgatat ttgcttctgg atagcgatga ttgatcacat ccaatagata atctacatct
    20101 tcttgtgtga ctttcggatc cgtaaaatct ccttggtaat ccgtatctgt cgtaccaaag
    20161 taagtcttgt tttctcttgg aatagcaaaa accatccgcc catcttgctt tcctgtatcg
    20221 aagtatgtgg gttgcggtac aggcagtttt ttcgcatcta caactaaatg gatcccttta
    20281 gttggacgca ttttaggaga gactggacgc gtaaaattca agtttcgtac tttatctacc
    20341 caaggaccac tcgtattgat cactaatttt gctttgattt cgatcacttc atctgtcagc
    20401 aggtcacgag ctttgacgcc aacgatttga tcgccatcat ataaaaagcc aaccgctttc
    20461 attttactta ctagataagc cccatcttcg gcagcctttt tgatattatc aatcactaaa
    20521 cgggcatcat tgttgcggaa atctagatag acacccgcgc cttttagccc ttcttttttc
    20581 aaaaacggtt ctctttccaa tacttcttct ggtgtcagcg tataattctc atatttggtt
    20641 cctgtcacat ttgccagttt gtcataaagg tccattgcta ctttgaccga gaacatattg
    20701 aaggttgttg ctccttcgcc ctcatagatt ggcaaaagca ttggatctgg ttttgggatg
    20761 tgtggggcaa tactttgtac gactgcacgt tcaccaactg tgtcagctac tacttccaca
    20821 tcaaatgtct tcagataacg aataccgcca tgaacaagtt tggtcgagcg agaggaagtc
    20881 ccttctgcaa aatcctgcat ttcgatcaat cctgttttga ttcctgatgc tgctgactgg
    20941 actgccacac cggcaccagt gattccgcca ccgatgatca acagatccaa ttcttcttgc
    21001 tgcatttttt gaatgctatc ttgtcttgtc ttgtttgaaa acatatggat ttcctcctta
    21061 ttcaaatgct tgggtagctt ttactgcttt tttccaaccg ttgtaaagtt tttctcggcg
    21121 ctcttcctcc atttgaactt caaatagctt gccagcttca taaaattcgc ggatctcgtc
    21181 tgtatctttc caataaccga cagctaatcc tgctaaaaat gctgccccta gcgccgttgt
    21241 ttccaagttt tctgctcgtt ggatcggtac attcaagata tctgtttgga attgcatcag
    21301 atattcattg tttgctgcac cgccatctac tttcaataca ggaatcttga ttccagtgtc
    21361 atcttgcatc gtatcgatga tatctctcac ttgataagca atcgactgta aagtagcttt
    21421 aatgatatct tcttttgtcg taccacgtgt caagccaaac atagcccctc gtgctgcctg
    21481 atcccaataa ggagcaccta gcccaacgaa tgcaggaaca acataaacct catcttcgct
    21541 tgtagagcgt ttcgctgcgt cttctgaatc gctagctttt tgcaacattt gaagtccatc
    21601 tctcagccat tgaatcgaag aaccagccac aaaaatactt ccttctaaag catagtaaac
    21661 ctttccattt atgccgtaac caattgtcgt caataaatta tttttggata attgcggttt
    21721 ttcaccggta ttcatgacaa taaatgaacc tgtaccataa gtattcttga ccatgcctgg
    21781 ttcgaatgcc atttgtccga ataatgcggc ttgctggtct cctgccatcc ctgaaattgg
    21841 tgcttcgctt ccataaaaat gataaccttg cgtataacca taaacttctg agttagaagt
    21901 gacttttggt aacatcactc gaggaatatt tagtaaatct aaaatctcct gatcccaatc
    21961 tagctgatgg atattgaaca acatcgtccg actggcattc gagtaatcag taacatgtgc
    22021 ttgtccatcg gtcagtttcc atactaacca agaatcgatc gttccaaaca tcaattcgcc
    22081 tttttcagct cgttcttgcg cgccttctac atgatcaaga atccagcgta tcttcgttgc
    22141 tgagaaatag gcatcgatca ctaaccctgt tttttcgtgg aaaaattctt gatagccttc
    22201 attttttaag ttatctgcaa ttccagctga ctgtctggat tgccaaacaa ctgcatgata
    22261 gattggacgt cctgtatctt tttcccatat tactgttgtt tcacgctggt tcgttatgcc
    22321 aatcccagca atctgatttg gtttgatccc tgattcgatg aacgctccgg caataactga
    22381 ctgtacagaa ttccagattt catttgcatc atgttccacc caactttctt gcgggaaata
    22441 ttgcgtgaac tctttttgag aactgccgat gtgtcttcct ttcttgtcaa agataattgc
    22501 tcgtgagcta gttgtacctt ggtcaatcgc catgatatac gttgattctg tcattgtgat
    22561 tccctccatt atatgcaaac gctttcttta actactctta tcatactact gttttaaaaa
    22621 aagaaactgt caaaatttta ttcttttttt ctttttttga cagtttttta ttatgaagct
    22681 attttttaat caattctttt cttttttcag cgtctctatt cttcttttca atcgaataat
    22741 gtcgtaaggt gacgcaaatt ctgacagata atattcacac tgttttttgt ttctctggca
    22801 aaatgtgatc accaaatcat attctttacc ttcttcataa cttccaatct caataccgcc
    22861 gattcccctc agttctctga tcagatattg ttgaaaagca atacgataaa tcggcagact
    22921 ttctaaatcg attccaatca ctactggttt tgcaatataa aaatcgatca tcaaaagaac
    22981 attggcatac tggatcatca ggtaactaag ctcactatct tcagctcttt tcctcggcaa
    23041 ttgctgcacc gctgtttcct gtaatttcgc cagtaactgt gttaaggaat gcccgagcat
    23101 tttctgctgc tgttccaaaa gccgatcacg ctcatagact tcgatctttc caacaaagaa
    23161 aaaccattca ttgttgatct gggaaatttg gtagcctact gccttttctt ctttgatttt
    23221 caaacgacga ggacgataat gccataacat cgtttcccga atgtaagtat ctaaaacagc
    23281 ggttggtaac tttttgctcc gtgtcaaatc atactgataa aatatttctt cgtctactat
    23341 cgaaaaagaa acaaaaaagc tgtaaaacat cattgtttcg tatacattca gttctgctgc
    23401 tgttcgacta agatgcatca cgatgattgg atcgattgct tgataaagcc ggtccgactg
    23461 atagagtaat ttcttttctt tcaaagttgc gtacgtactt ttttcattca atagtctttt
    23521 tttcgtaatc ccgagccagc aagcaatctg tgcttctgct gatgccgtaa acgttgtttc
    23581 taatacacgg tccaatccta gaatgaacgg tcttttttct ggtgtatttt gcaaaaaaag
    23641 cggtcgctga tcttccggga tatattggaa tagttcataa taaaaatatc gtatctgtag
    23701 ctcttctccg tataattgac cgtttttgat ttgtaatcca aattcctcta agagctggtt
    23761 caattctttg atctttcgaa aaacagaaga ctcactgata ttaaacgctg tcgctaatcg
    23821 aacgatggat acttgctgat gttctaataa atagacgagc atcttaaact tcaagctttc
    23881 ctgcaataaa aacaatagaa ttttttccaa acttacatct tcgtccaaca caagcagcgc
    23941 ctgatactca tttcgctgta cttctacttt tttttccatc attcggccaa tcaattcaat
    24001 atcttccaaa tattgatcaa acgaggcttt tgacagttgg acatgctctc tcaaaccatt
    24061 gatagaggct gttccccctt gcagaacaag gtttcgcaaa atcaggatct gtaactgctc
    24121 ttttctttct aataatgctt caatcttcat aggcagtatt cgccaccttt gaccacacca
    24181 tatctggcac acggtattct ggctggaaaa atagctcatg ttcttctaac tgttcaaacg
    24241 tccatccttc ttctactgca attgtcagtt ggtcaagaag gtggaacatc tcttttttgc
    24301 tttggagctg tgctccaaga atcttttttt cagaatcaaa tagaaatttg agtttaactt
    24361 tgctttgatt tattgctgta agcttgtagt ctacgtatcc tgtttcaatt ttttggggat
    24421 aaaaaatgct ctcttcttct gtcaaaccta cgcttcctaa gaaatagcca aaccactgat
    24481 tgccgactgg acgataggtt ccctgatcct ttgtctgtga gccactaatt gtcttgctga
    24541 catttcgtgc tgtacggaca gcgttattta ctagagaaac atacattttt tcatttgttg
    24601 gacgaaaagt tacttggatc gcatcgccaa tcgcataaac gtctttttga gacgtttgca
    24661 agtagtcatc tacccagatc gttccatcat cattcaatgt taattgttct tcccacatct
    24721 gattgtcggg acgagaatga ttagccagca aaacaagatc atagttctcc tttctttttt
    24781 ccgtctctac aatagcggtt tcattttcgg tcaaagacac aacttgttct tctaaaaaaa
    24841 gtgaaagccc ttgatttttc atttccttta ctaacggttc tgtcatttca ggatctagat
    24901 aacgaaaaag aattgacttt cggctttcgt aaagatggat ttgttttttt cttgatgcca
    24961 acccttcagc tatttcgatt cctgcttgtc ctgcaccaat aattgcaatt ttctttgcat
    25021 tcatgatctt ttgctgaaga gccgttacgt tttgtatctt tttaactggg tgaataagcg
    25081 ttgattctgc agaaatattt cgaaactttt gatttgaacc agtcgctaga atcaaacgat
    25141 caaaatccaa tttttttcct cctgctaaaa cgactttttt ttctttcaat cctattactg
    25201 tcttttctgt gtaaacatgg attcgatagc ggtcagtcag ttcttctttc gtgatccaag
    25261 aaagttgttt ttcactggta acctttcctt ttaatatcaa attgaacccg ctgggaatcc
    25321 atcctaactt cgattgcttt tcaatcaaat atatttcact tgttggcatc aattggcgaa
    25381 gataaatagc cgcatgaatc cctgcaaacg acccgccgac aattacaatg ttcatctgca
    25441 ttcctctttc ttataaggtg ttctactgct aacttctcaa tcagaaaaca cagtattcat
    25501 aactcgcttt caaccttatg atacatagcg atgcagcaga atcaaccctc tccatcatac
    25561 cgtgttctag gtctgcttct caataatgta ctagtggacc taattgaaga gtatcatttc
    25621 tgaagagatg tttcaaaaaa tgtactctta taaaagaaaa aaactcgcct tttacgtacc
    25681 tctgtccaaa taggaaacag aaaagaacga aaagacgagt tttagcgtgt gtaatgtaat
    25741 agttagaata gacacatcat ttatttttaa ttctttaatg cttcaacaac tgcttcgcct
    25801 aattgatgag cagattgagg attttgccct gtaagaagcc gcccatcaat ttgaaccact
    25861 tctgaaaaag ctgctccaga ctgatagttt gctccttttt ctttcaaagc atcttctgct
    25921 aagaatggta cttcattcgt tgtaccattt gcttcctctt cttcattact gaacccagtc
    25981 actgtacgtc cagctaaaat agattttcca gactcatctg taactggcaa caatcctaca
    26041 acaccgtgac aaacagctga gaccagccct tcatttcgat agatttgtga agcgactttc
    26101 ccaagatcta ttgcttctgg aaaatcccac attgttccgt ggccaccagc ataataaacc
    26161 gctgcataat catttgcatc cacatcatca ggacgtaagg tatttcccaa ggcccgattt
    26221 ctgaaatctt catcttcata ataggcccaa tcgatttcat ccatattcaa aacactttgc
    26281 ggttctaaag gtacatatcc gcctttagga ctgacaaaat ctgcatcgat cccatttttt
    26341 actaatacat cataaaaatg agtcagttca cttaaccaca aacctgtagg acgctcgatc
    26401 ttttcgtact tttctacatt tgttaatacg atcaatactt tcattttccc atcctctttc
    26461 tataaaaatt gcgttattga taacgtgctt tcaagaaatt atataatggg cttggcaaat
    26521 aaagctcttt atatgcttct tcaaaaggtt tcgttacaaa ttcatcctca cggttttcca
    26581 ataatttctc tgcccagtca ggatcgacga tcatttgctg tccaattgct gcaagttctg
    26641 catatttcaa tacctgctct acatcttcgc gattgcggat cccaccgaca ccaactaaag
    26701 ggatctttcc ttgaatcgtg ttatggacca cttcaagaat cgatttatcg ttgtatttat
    26761 cagaacgagc tattcgatca tacatattta atgaaacatg cagataatct agttttgact
    26821 cacgtaatcg ttcaagaagc cagatcgtgt cttcaaaacg gatacctggt gtttcatatt
    26881 cttctggtga gaaacgatac cctacgatga atggtttttt agcatattgt tcaaccgctg
    26941 agaaaaccgt tgttaataat tcttcaataa aacgataacg attttccaag ctaccgcccc
    27001 attgatcctc tcgtctattc gaatgcggag agaaaaattg ttggatcaaa tacgtatttg
    27061 ctccatgcaa ctcgattcca tcaaatcctg attcaatcgc tctacgtgtg gctttgccaa
    27121 atgcttggat tgtttcaacg atttcttctt cactcattgc tcgtggtgtt tccgcatcag
    27181 gacgttttgc tgcaactgca cttgcagata caggctgttc tccagataaa gttgctcgac
    27241 ttgtcattcg tccaccgtgg aaaatctgaa taatcgcttt tgcgccttct ccttggattg
    27301 ctttcgctag ctcacttaat cgaggaatca tttcatcatg agcgatgctg agttcacctg
    27361 gccagccttt tccgatatct tggacatttg cagcaccagt aataacagca ccaagacctt
    27421 tagaacgttg tttataataa gtgatctcat cttcggtgat cactccattg aaaaagctga
    27481 gttgtgtcgt cataggcgac agcatcaatc ggttcttcaa ttgaactcct gaaggtaaag
    27541 taattgattg atcaaattgt gacattgtca ttcctcccat aattcgctct gattaaccta
    27601 tcgagaatca tctatcatta aaccactcga ttagttgtac atgcaactaa tttgcttaaa
    27661 aaattttatt ttttttgtaa cttatctgtt gcatcattca ttgtctgggc taattcttta
    27721 cttgcttcat ttcccaaaac tgctttgtat gactgatgaa gttcttccca gctaccatcg
    27781 acttccttag caaattggcg tccttgttct gtaagataaa ctaatgacaa gcgaccttcg
    27841 ctaactgttt tgacgtatcc tttatattct aatttttcaa caaaacgagc aatcgttgat
    27901 ggggcggaat agagcatttg tgcaatatct ttttgtggta ttccatcttt ttcttttaat
    27961 atcaataaaa taaaaccata agttggtgcc agacctgtcc ttctaaacgc ttcatcagct
    28021 aatttattca acatgcgatc tagctttttc acgctaaaga aaagacattc atctaacgct
    28081 ttttcaattg gcttttccat ttcatcccct ccattggcgt acatatcata gtatgatttt
    28141 tattttttgt caaaaaacac ggaataatgt ccgcctcctc tgtctagatt tgaaaaaaag
    28201 aagtagccat cttcaaagaa tttcggcttg ttttcgacaa aactccttct ggaacaccgt
    28261 gaatcagagg ttgtgaaaaa gtcgtttagt tttgagtatg aagaaaaatt ttgtgaaaat
    28321 ggctttccac atttttgcat aaatttggct taataccgaa aaactggctt ttgaacaccg
    28381 tttatatcag aggttgtgaa aaagccgtcc tgcatcaagt aataagaaca gccaaacaaa
    28441 aatagttcct catattttgt cgttttttga gctaatgccg atggtcagct gattgtacac
    28501 cgtttattga gaggtcgtga gcctgccgtt gaactccgag tcacaaggag caatttcaaa
    28561 aaacagcttc tcatgtttta tgactatggt gacttgtgat cgaggagttg gcaggagaat
    28621 actgtttatt cgtaaagaag gggctgtgac aagacttttg tcacagtccc ttatttcctt
    28681 ttattatagg atttcgccat ttgattggat gacttgtctg taccaatcaa atgatttttt
    28741 ctttaaccgt ttctttgtgc cattcccttc gtcatcttga tcaacataga tatatccata
    28801 acgttttgac atttgtgaag tagaagcgct gacgatatca atgcagcccc acgacgtata
    28861 accaaataaa tctactccat ctttgatagc ttccttcatc tgctcaatat gctgcttcaa
    28921 atagtcaatg cggtaatcgt cttgaacggt tccatcttct tctactttgt ctatagctcc
    28981 gagtccgttt tcagctatga acagtggttt ttgataccta tcatataatt gattcaaagc
    29041 aattctcaaa cccttaggat caatctgcca gccccattca cttgatggaa gatacggatt
    29101 tttaattcct ccagttatta agtttccttg gaccccttcc caattttctg gatgagcact
    29161 gactgcacta gacatgtagt agctaaaaga aacaaaatca acagggtagg ctgctaagat
    29221 ttcttcatca cctacttcta tttttaagtt gacacctttt tcttcaaaca ttcgttgcgt
    29281 atacgctgga taatatcctc ttgcttgaac atcactaaag aacaaagaag ttctttgctg
    29341 ctcaattgtt ttttgaatat catccggatc acaagaatac ggaacaagaa gctgatagct
    29401 gatcatacaa ccgacttgtg aacctttgat aatttcatga caagcttttg tagctaaagc
    29461 acttgctata aactgatggt gtgcaccttg gtatttcgct tgttccaaat ggggatggtt
    29521 ttcttcaatt actcctacgc taacaaaagg gtgatgtttt acacagttga tctcattgaa
    29581 agtcatccaa tattttactt tatttttata gcgtttgaat actgtttcag cgaaacgaac
    29641 gtaaaactga ataagctttc gattaggcca tccaccatat tctgtaacca aatataacgg
    29701 catttcataa tgggaaagag aaacgactgg ctcaatccca tattttagac attcgtcaaa
    29761 cacttgatca taaaaaaata atcccgcttc attgggtgtt tcttcatcac catgaggaaa
    29821 aattcttgtc catgcgatag acatccgata gcatttaaaa cccatttcag caaataaacg
    29881 gatgtcttct ttaaagtgat gatagaaatc atttccgtgt cttttaggat aataatactt
    29941 gctgttggga tcctgcgccg cttttacttg ctgatgcgtc atcatatgcc attgatctgt
    30001 ccatttttct ttaggtaaat cgctgtcgaa tgtatacaca tcagacacag ataatccttt
    30061 ttcatctaca tcccatgcac cttcacattg attggccgct gtcgctccgc cccataaaaa
    30121 tccttctgga aattttttca tatcgatccc cctaaacttg ctagttttct tgtttgatta
    30181 tttttcttat gactagtaat gatatttttg aatctactac tatttgtaac aataaccatt
    30241 gtggtcggat catatccctc tttgattaat tcttgcaaat ctacttccat caataaatcg
    30301 cctttacgta ctttttttcc atcagatact gcactttgaa agtatttgcc atttaaattc
    30361 actgtatcaa taccgatatg gatcagtatc tctgctcctt cttcactgac taccccaatt
    30421 gcatgtttcg ttggaaaaac tgttgaaact tccccgttta cagaactgta gatttttccg
    30481 tccgttggaa tgatcgcaaa cccttctcct aaagatccac tagcaaatgt tggatcgttt
    30541 acttcagata aatcaattat ttcacctgct gcaggagtac ttaacactat atcctttgag
    30601 gattcttctt cgatttcatc cttgtagccg aaaagaaaag ttagcataca ggaactgatc
    30661 atcgctaaga aataactagc aactagccaa acaaatcctt caccaatata aatcgggaaa
    30721 gacaaaatac ttcttgtagc aactgccaaa gcaccggctc ctgcggcacc agctactcca
    30781 ccaaatatag ctccacatat acaagcaatg taaaatggtc gtttatattt aagagtcaca
    30841 ccataaacag caggttcagt gattccaaat aatgctgtga taaatgcaga taaagataaa
    30901 ctttttactt tcttattttt cgttttcaaa aataccccaa gtactgctcc tgcttgcgca
    30961 gctacggcag tcatacatgc tggacctagc gtatcacgac cgtagaaaga aagattgttg
    31021 gtcattactg gtacaagtcc ccaatgtaac ccaaaaatca ctaacacttg ccaaaatccg
    31081 ccgataacag caccagataa aacagggcta aagttataaa cagctaaata tccagctgca
    31141 atcagctgac ttgcataatc tgcaattgga cctacaacta ataaaataat tgggaccatc
    31201 acgatgatac aaatgaatgg tgtcaataaa tttcgaatac tttcgtgcaa gcttttgcga
    31261 atcttaggct caatataaga aagaacccat acagctaaaa ttgctggaat aaccgtactt
    31321 gtataccttg ctagaatcac gggcatccct agaaatcgca aggttatgct atcactatat
    31381 gcactgacaa tcgtaggata aacgagagct gctgcaataa ccatagcgat gaaacgatct
    31441 gtattgaact tttttgcagc agtatatgcc aaaaatatag gcaagaaata gaaaaatgca
    31501 tcagctgctg cattcaaaat gatataagtt cctgattcag tagttaataa attcaaactc
    31561 gtacataagg cgagtactcc tttgatcaaa ccacttcctg ccaagacgcc taaagtcggg
    31621 gcaaaaacag cggcgatcat gtctataaaa gagtttaaaa tgcctttttt ctcagttcct
    31681 ctctttccac tagatgcatc atcttctagt ttcatttgtt tggataatac gtcatacact
    31741 tcatttactg catttcctac tacgacttga aacattcctc cagcttcgac tacagtgatc
    31801 acaccttcta gttgctctac cttctcctta tctgccttct tattatcttt tagggtaaag
    31861 cgtaaccttg ttgcacaatg gtaaacattg ctgacatttt cttcgcctcc gacaaatcgg
    31921 acaatatctt tcgctaattg tgaatagtcc atttttactt cccccttgtt aattaatgcc
    31981 gtagcaatcc ttcttacaag ataagtatag ttcttagaaa acggtttctc cattcaatta
    32041 gtaccccttc taatagcgaa cgaaactgta caatagtgtg tatggtttac ttagccgagc
    32101 aaatcactca ctgcttgaaa gaaaacaagt atatcgtttc tcttatagtc aaaggagaca
    32161 aaaaaaacac gcttgatctt cctttgctga tgtataagtg gtatctcaag ctgatactct
    32221 gtgatttttg tttctacttg gcttttgata agacagcaca acaaagtctc ggcatttaac
    32281 ggaagcataa ctaggtcaga actaggagag attagttgct gaatggaatc tatcttttta
    32341 tggattttta tttgattttc ttctttgtag taatgatcaa gcagttttgt tttctttttt
    32401 tcttcaacta tggtcagctt ttcacgcaaa atctgataaa tctcccaaga ttcaaactca
    32461 tctagaacac taggtagata aatcaaatca tcccactcaa aaataagctc ttgctcagta
    32521 gtcaaaattg catcatattc cgttattttg tttgattgat ttttgaaaag atacactggt
    32581 tctatccggc attctttgat ccacatgttc atactttgtt gaatctgttt ttttagtgta
    32641 ttcaaaatac taattggctg gttactaaca atcagtatct ccccttgttt tcgaaaagga
    32701 ttcaacgctt cggcaagata caaaacaaaa taagcgcttt cagctaaatt gggacgtaat
    32761 tgaaaatgta ttgggaagaa acgccgaatt aaataaattt ctaaaggata acgggagatg
    32821 atcttttgta caaaatgatt catggtatta tgtccggcat ccatcctcgt tttcatttgt
    32881 ttgatatggg ttagcaaaaa ttctgtttca tggaacaata acgaaacagg aagatctaaa
    32941 aaacgaataa tcgtttgctc aaatgctctt agattcttct ctatttcttt gtttttttca
    33001 tcattaatca tcaaataatt taactctaat agtcgatttt caattgcttg tttttcttga
    33061 ttggaaaaag aatagggtag ttctgatgat aacttttttg tgagggtctc taccatcgga
    33121 ataaataatg tatacctgtt tgttttttct aaaagttctt ctcttcgaag aatggtcaaa
    33181 acgagatacc gagaaaatcg tatgaagtcc tctcctgaaa caatataatt atatgatata
    33241 agaacctctt ttaatgtctt ttggacagtc ggcatgatat tggaaaaaat tgtactgatt
    33301 tgttgaggaa accttgcgtg ttggatcacc gtttctgttc caacaagaga taagaaaatt
    33361 ctttttgaat tttcttcagc aatgattttt agtccttttg tcgacgaaac ttccagttct
    33421 aatttaggat tgcgctcgat ccaacgcaaa atcgttttta tttgtaatga tacggctgtt
    33481 tttgaaagaa agaaaatgtc tgctatcttt tgcatactga catacccttt ttgaaacaat
    33541 aagtacgtca caatagttga agctcggaaa tccatgctgg aatagatttt atgtttcgtc
    33601 acctcttgta tgatttgctg tttagtttca gattcaattg attctaaaaa ataacctgaa
    33661 cgtttatttg actggataat gattttcttc tcgtagatag caagcatatt tttgatttca
    33721 gtttggatcg ttttcttgtt ggtacctaaa gcttcagcta attcttcgct tgttatccaa
    33781 tgattcttat ttcttaatac tacaagaatt tggagttgtc gtttatttaa gtccatttgc
    33841 ttacacctcc tctttgttat aaacatacag gaaaaacctc tcaaatgaca atagtcactt
    33901 gcagaggttt aaaaatcatt tgaagaaaga tctatattca aggtttttac cattagactg
    33961 gataatttgt ttataatatt caaaactatc ttttttcaat ctcctaaagc ttccgctccc
    34021 atcattttgt ctatccacat aaataaagcc atatcgcttc ctcatttccc ctgttcctgc
    34081 cgatacgata tcgattggtc cccaccataa gtaaccaatg atttggcaac catcttttat
    34141 tgcctcagca atttcctgaa gatgtatttt tagatactca caacgttttg gatcgtggat
    34201 tcgattcaat tcatctggtg cttcatctag tccaatgcca ttttcaacta tgaataatgg
    34261 taattcataa cggtctgtca attcattcat gacataacga aaccctagag gatcaattgg
    34321 ccaactccaa ggttcgggag atttttcctt caaaaaggga ttatcgaaac catttgctcc
    34381 gccagtatct acgcgcattt ctgcttcttt tttatagaca gcgctacgat aataactaaa
    34441 tgcaatataa tctgccgtgt tagcttgcaa gcactgttcg tctccatcta acattactgg
    34501 tgcacagtct tcttccttcc atgtcctgta aatataagct ggataatgcc ctcggcacat
    34561 gacatcggag aaaaaccatg aattgcgttt aaattgcagt gaaccaaata cattctctgg
    34621 atcacagtca tatgcataag tcgctaatgc agaaaagcta cacataatac ccatcttagc
    34681 atttggatcg attttcttta ataattgagt agcacgggcg ttcgctagaa acatatgatg
    34741 acaggcttga taaatcactt tttttgttag tgtagcaatg ggttcaagtt tatctctagc
    34801 agggaatgta accaatccag cagctgcata aggcatacga aaagcattat tgatctcatt
    34861 aaaggtcatc caatatttca ctttcccttg gtagcgttca aagacggtct gcgcataaaa
    34921 ttcaaaaaag tcgattaatt ttcgattttg ccacccccca tactctccta ccaatgctaa
    34981 gggggtttca taatgactaa gagtaattac tggctcgata tcatatcgat ttaatgtatt
    35041 gattagtctg tcataaaata cgagaccagc ctcatttggc ttctgttcgt ctcctcttgg
    35101 aaatattcgt gcccatgaga tgcttgttcg aaaagctttt aaacctaact ccttcagtaa
    35161 acgaatatcc tcttcaaatc gatgataaaa atcaatcgct tcatgagaaa gataatggag
    35221 tgattcgtct aaagcaatct cccaaatctt tttttcttca ttccactgaa tactaggatg
    35281 ctggttcatg atcccgataa gcgtatctgt cacattaggt aatttgccgt cttccaacca
    35341 tgcaccttca cattgattag cagctactgc tccgccccat aaaaaatttt ctggaaatat
    35401 ttcctgatcc ataactatct ctcctcgcta tcaacaattt cttacttgaa gtatagctcg
    35461 attcatcaaa acaagatatt ctaactattt cggcagaaga gaagaaaaaa attgaatgct
    35521 actcttcatt tttaatattt atatataaca aatacataag acgatccccg aaagaaaaca
    35581 ctcgttaacc atctaagcaa acgatttatt ttacttccaa cacaaatgct tcataaggtc
    35641 gtaaatcaac tttgccgtct ggtaactgtt tcagaggata atttgacaca ataaccctta
    35701 aagcttcacg tggaatagtg aacgtctgct tttcactgga catattacaa ataacgagcc
    35761 attgctggtc ttcatatatg cgagaatagg caaagacatg ctcaggcgtc ttttccacta
    35821 attcatagtc tccccagacg atgatgtcat gttttctacg caaatcgatc aatttcttgt
    35881 acatataaaa aacagaatct tgatctgcta acgcttcttc tgcattgatt tctttataat
    35941 ttggattgac tcgaagccat ggaattccag tagtaaaccc agcatgttca cgggcgttcc
    36001 attgcatagg cgtcctagca ttgtctcttc ctttcgcctt gattgattcc aagatttcct
    36061 cttttgtaaa tccagaagaa atcctttcgt tatacatatt gattgtctca atatcttttg
    36121 cttccgcgat atcatcgatt gggcaattcg tcatgcctaa ctcttctcct tgatagatat
    36181 aaggggtgcc tttcatcata tggagcaaga tagcaaacat cttggcactt tcttttcgat
    36241 acacatcgtc atttccccaa cgagaaacaa ttcgcggaag atcgtgatta ttccaaaata
    36301 aactattcca tccttcatca cctaaagatg tttgccattt ggataatact tttttcagtt
    36361 cagagatact caagggtttc aaatcccatt tgtctttgcc ttcttgctga tctaatccta
    36421 tgtgttcgaa ttggaagacc atggataatt catttctttt aggattggaa taaagtttag
    36481 cgatttcggt agttgctccc catgtttcgc caacagtcat cagatttttg tcaccaaaag
    36541 ttgcttgatt catttcctga agatactcat gcagtttagg tccattactt gtgatttctt
    36601 tatccggttc tttgccaatc atatcgatca cgtccatacg aaagccccca atacctttat
    36661 cgatccagaa attcatcatt tgataaatct cttggcgaac ctgtttattt ttccaattca
    36721 aatcaggttg acgcttgcta tacaagtgca gaaaatattg ccccgttttt tcatccaact
    36781 gccaagcaga accactgaat attgagcgca atctattagg ctcttttcca ttgaccggat
    36841 cacgccaaat ataatagtcc cgataaggat tttctttatt tttacgggcc tcaatgaacc
    36901 acggatgttc atcagaagta tgattcacca ccagatccat gatgatacgg atatttcttt
    36961 tctttgcttc ttcaatcagt tcttccattt cttccatcgt accgaattct gccatgattg
    37021 cttgataatt actgatatca tacccattgt catcattcgg agactcgtat actggagaaa
    37081 gccaaattgc atcaatacct aaatacgcca gataatccaa cctggaaata atcccccgca
    37141 aatctccaat accatcttga tttgaatctt gaaaacttct tggatagatt tgataaacaa
    37201 ctgaatggtg ccaccatttt tgttccatga ttttcctcct ataaatggat gtttctattt
    37261 tttgcttaat catttatttt agtctctctc actaaaaatt gtaacgcttt caaatagcta
    37321 ttgcaccttg ttatcggtaa cagaataaaa caaaaaaaca gctgaggaaa ttccctcaac
    37381 tgttttttga aaggattgat ttatgcaggg aagaatgctg atttcacaac ttctttataa
    37441 acggtgttca ctcagctgtc ccttggtatt agctcaaaaa acggcaaaat ataagaaact
    37501 attttttcgt ttttttctct aatactcagg ccagaacgct gatttcacaa cctctttatt
    37561 tcacattcaa tatccacatg aatcccacaa atacaaagaa cagaccatac atgattggag
    37621 atacttcttt tcctctttta gctgctaaca tggtaattgg atagaagata aaacctaatg
    37681 caatcccatc tgaaatacta taagtcaaag gcatgccgat caagatcaag aatgaaggga
    37741 tcgcaatctc taagtttccc cattcgattt gtcgcaaaga ttgtgccatc aatactccta
    37801 ccataatcaa tgctggtgca gttacttgtg aagtaacaac tgatagtaat ggagaaaaga
    37861 acaagcctaa caagaagaaa atccctgtag taatagctgt gatacctgaa cgtcctccaa
    37921 cggcgatacc agctgatgat tctacaaatg caccaacagg agaagtacca aataaggaac
    37981 ccgcaagcat agctgttgaa tcagaagcta aagctttccc tacacgaggc atcttgttgt
    38041 ctttcatgaa acctgcttgg tttgctaatc caactaaagt tcctgctgta tcaaagaaag
    38101 tcacaagcaa gaatgtcagc actacgaccc acatttgaag agaattgatg tcccctacat
    38161 gttttaatgc aactaaaaat gttggtttca aacttggtgc tgcggcaaca atttcagaag
    38221 gcattggaat caaacctgtg accagaccta aaatcgttgt agctgccatc ccgatgaaga
    38281 tgccacctgg tacacgccga acaagcaaga tagcagttac gactaatcca aaaatcgtca
    38341 accaagtaga accaacgttg agtgatccta atcctactaa tgtagattca ttcgaaacga
    38401 tgatcccacc ttcgctcaga ccaaggaaag cgataaatag accgataccg ccagaaatcg
    38461 catatttcaa atctgctggg atcgcatcaa tgatcatttc ccgcagcttg aagattgtga
    38521 tcaaaataaa aatcaaagaa gcaacgaata cgccggctaa tgctgtttcc catggaatcc
    38581 ccattcctaa acaaacagaa taagcaaaaa aagcattgat cccaagagca ggtgccgttc
    38641 caattggata acgggctaat acccccatta aaacacagcc gatcgcactg gctaatgcag
    38701 tcgcagtaaa cactgctcct tcatccattc cagaagcacc taatacagtt ggatttacaa
    38761 ataagatata agccattgag ataaatgttg taaatcctgc cagtacctca cgttttaccg
    38821 tggtgttcaa tttttctatt tcgaagtagg aaagtatttt ttccttcatc ttccatcccc
    38881 ctaaatccga acattataaa taaagtccgt taaaatttcg atttattaat aaaacaacgt
    38941 gttttatcat atactaaaac aaaacataag taaacaaaaa attcggattt taagcaaaat
    39001 ccgaacgttc catctgatta aatcccttta tctcaaagtt catgaacatt cactttggat
    39061 tacaagaatt tctttattgt gttaataaag tttcttcatt ctagtctcaa aaatcaatag
    39121 tgtgatttga ttttaccatt tcgtttctgt tcttctttga tgaattcttt tgtatcgaca
    39181 ggattcagat tatttagtcc gccaaaacct gtatcgacca tttttcccca gccttttgtc
    39241 ttcttttttc ctgatttgag attctttgct cgaagcttct cactatgttt tgctcgccga
    39301 tacttcaaat aaccttctaa tcttcccatt agatccactg tttttcctcc tttttattca
    39361 atcagacgac tcagcttttc ctataacaaa ataattgcct tcagggtcag aaaaattgaa
    39421 agtcaagatg ccattgttat ctgtgatttc tcctggttct tccatgttct cgtagatagt
    39481 ttcaaattca tccgtaaaaa atactaaaga aggcggtggt cctaatacct ctggtgaaaa
    39541 cttctgcaca aatacttttg ggaatacgcc taattctaat tcttttgaga tgctgagtac
    39601 aatactctta aattcttctg gcaattcgat tgtttcagaa atttctgcac caattttttc
    39661 tacaaagaat cggcaaatca tctctacgtc attgacataa agcatcacac gtgttttttg
    39721 tatcatcatt tgacccttct ttctatttga ttttctttcc tgtctataaa ctgattccat
    39781 tatatcacga aagcgcaaac accttgtgtt tgatactatt caagaaaaat aaagcaatag
    39841 tttctaggat tgctttcctc cacaaacttt ttttacaaaa aaaaaacggc aatgaatgcc
    39901 gctcttctta tttcgattct tttataattc tgcttctgat tcatctttgg ttagtgtgtg
    39961 tctaacacta gttacgccaa atgtttgatc gattttttcc ttcaacgctt cgattgcctg
    40021 tgcgccacgt gccgcttgtt cagcattgat ggattcaatg accagcaccg ctgcttgtgt
    40081 ttcttccgtc agcatcgttc tttgggcttc acgccagttg agacagcgac agatcgctcc
    40141 ttgttcatca tagtagatga tttcttccgg aagtgccgga gcatcggaat ctgcacctaa
    40201 aggcaggaat gattcgccac cttgggcttt tcctaaatgc agatttcctg cgatcttttc
    40261 gatatcttct ccgccgcaag gtacgccaaa agacaaggaa atactattat agatatctac
    40321 aagcggattg attgggaaaa attcccgttc ttgatttgca cgtttcagta aagcttcaat
    40381 agaagaacgt gcaccttttt tagtcttgaa tgtggtaaat gcctgacgcc actgagcaat
    40441 gacttcgttt tggctgaatg tttcttctgt aaggtaattt cttgcttctt ttgctgcctc
    40501 attcaataat tgatgatacg tttcttcact ttcttttgtt acgtggttat cgataccatt
    40561 tacggataag atttcgatgg ttgcttcagg aaatacttcc cagaaattgg tatccactat
    40621 tacttttttc atctgttcac acctcttgat tagaataatt gcttgatgaa tagatagtct
    40681 gtttggggat catctcccat ataaaaaaca tgttcgctgt atttgataaa tcctttttta
    40741 cgataaaaag cgagcgcaac atcgttgtgt tcccaaacac cgagccaaat ggctgttttt
    40801 tgcttttctt ttgctttttc aatagctgta tctagtaaaa atgtaccgat accttgatgt
    40861 ttaaattttt ttcgtacata gattcgctcg atttctaaaa aatgatcagc catttcctca
    40921 gattgactcg ttcctgtatt tagtttcagg taacccgcag gctcttgatc gatactcact
    40981 aggaaaaaat cggtttcttt atcttttagc tcttctgtaa gtttttctag tgcataagct
    41041 tgtgtcaagt aatcagctaa atgctccggt gaattatctt ttccaaatgt atctgtaaat
    41101 gtttcgatac taatttgttg tagtaagtct acatctgaag gcgtcatttt tcgaatttcg
    41161 tatttattca cggcttcttc ctttcaatag atccttttat tgcctttttt gacaaaattc
    41221 caatcttcgc taacattctt gcatacttta tttaaaagat attccaattg ttttgcttct
    41281 tcgtcagaaa gaccatttaa tgcgactgca ttggagtagt tgttttctcg aatgatgaaa
    41341 ggatagattt ctgctccttt tttagtcgga tagagtttct tgattttttt attttcttta
    41401 tcttccaaac gttcgatcat cccattggat tctaatttct tgattgctcg ggcagtcgtt
    41461 gtacgatcta ctttgatcat ttctgctagt ttttcttgga tgattccagg attttcgcaa
    41521 atacgtacta aataaagata ctgtcctctt gttaaatcga cttctttgaa ttcgatattg
    41581 ctaatagaat ctagcgctcg ggcaatcatt ccgatgtctc gaaggatttc agccatttca
    41641 tcccaccttt attttgtttg taagactagt tcacctcttt ttgttgcaaa tgcaactatt
    41701 ttcaataaaa aaatcaagtt cttttttaat aactagtaaa gtatattctt ttcttctttt
    41761 acgaaaaagc tcaatcacaa tagatctggt ttttgttttc taaaataagt aactgtttct
    41821 tcgttgttcg cttttctgat agctttggca actcttctat actaaaaaat cccatgttgg
    41881 aagtttcatt attctcaata aacttggcct cttcaccgtg gatcgcacaa gcaaaaacaa
    41941 gtttataata ctgaaaaagc tgtggaatat ctttttgttt attcgtatca aaaactgctc
    42001 gcaactgagt agtttctact gttaatcctg tttcttcata gacttcttta cgcacatttt
    42061 cttcaggaga caatcctatt tcagcaaatc caccaggaag tgaccattct ttcgtccgtt
    42121 tatcttcgat tagtaggacc ttgccatctt ttttgatata ggcacgaaca tctacttttg
    42181 gtgttggatg tccttctcca atcgttgtga gcgcttttat ttcttcgaaa gtttcttttc
    42241 ctatttcact gatcagttcc aatgaaatcg tccggatctc ctcaaaacgc tctttatcaa
    42301 atacatcttt tccataatat agaccagctt gagaaagtgc gagtagtctt ttgtattgag
    42361 ccaacttctt gttcattctc ttcccttctt ttttagcaaa tgtatgacta tgtaatcaag
    42421 tatagaagac tggtttaatt acggcaaata aatataatga aatctgcaat aaataaaaga
    42481 atgttaaaaa actcgagaac aaaagacatt cgacttctct ggggctgtga ataaatggcg
    42541 ttcaaaagct tgcatctgcg gtaataagcc ccaccaaacg aaaaatatga cgagctattc
    42601 ttgtctggct gttcttatta attgaggcag gacagctttt tcacaacctc cccactaaac
    42661 ggtgttctcc taccaactcc tcggtcacaa gtcacaatat tcatcaaaca tgagaagctg
    42721 tttttttgaa attgctcctt gtgactcgga gctgaacgac aggctcacga cctctcggta
    42781 aacagcgttc aaaagccaat ttttcgatat taagccattt ctttgttact tattgtcatt
    42841 gatttctttt tctaatttat ccaatagtgg agtgtaatcc acttgagtat agtctgttac
    42901 atcaaattca tatagtgttc ctaactggaa tttgtcatat tttcggtcgg cgatgatctt
    42961 tttgaatgct tctttcgtaa tatgattggt ccctttcgtt cgatcttcca atacgtcacc
    43021 atagtgataa tgatccatga tatagctcaa atgacgatct gattcacgat cacgtttgta
    43081 ccgacgttgc cataacactt caaagtctgc tgttaggcga atcgtgatca cctgatatcc
    43141 gtatctatct gctaattctt ggagtcgtgc tttttgctta tcactaaaag gatactcgga
    43201 cacaatcact ttctttcctg cttccatata caaatcaagt gctttgtaat agaaaggata
    43261 aactttcgtc ctttcttgtt ccgcccgttc ttccaaattg ttaaacccga tggattctgc
    43321 atagtattcc ttgatttcat cgagcgtgat ggcatacata tctggaaatc gttcccgtag
    43381 tttattcata agatatgttt ttcctgtacc aggactacca gccagaagaa tgaaatactt
    43441 tttcatctca tttatttcct aagttaattg gactttccaa gttcataaac agtccaatct
    43501 tatgcttgac aatttctttt actgcttcat ttgctggaat cacattatgg cgaagagact
    43561 tgttgatttc tgtttcacta aaggtttctt tagctacttt cgtccagttg actaaaagct
    43621 ccgttccaac attgaatttg cggatcccgt tattgatcaa ttcaggataa tcttcttctt
    43681 tcacacctgt tcctccatgg ataactaggg ggacatcaac tactgcatcg atttctttca
    43741 gcaagggaat gtttacttct gtttttgatt tgaattgtcc atgattcgta ccgatagcaa
    43801 tagctaatgc atccacgcct gtagcttcta caaatttcac tgcgtcttcc ggtcttgtat
    43861 ataccttgtc attttcagcg acatggattc cttcttctgt accgccgatt gttccaagtt
    43921 ctccttctac ggaaacaccg tgcgcatggg catattctac tactgctttt gtcttcagga
    43981 tattttcttt gaaaggcaga tgggacccat catacatgac agaagtatat ccgctgtcga
    44041 ttgcttcttt gatatcatca aagtctcggg cgtggtctaa gtgcaagact gcatcaacca
    44101 tttcttcttc tgcaatagct gtcattacat tgactaacac atgcatgccg atatatttag
    44161 cggtatcgac acttgtttga ataatgatcg gcgaacccat ttcttttgct gcgcctagca
    44221 tagcaggaag catttctagg ttatgcgtat taaaagctcc aactgtaaaa ttcaactctt
    44281 ctgctgtttt tgttacttct ttcaatgttg tatacatctt ttattgccac cttatctttt
    44341 tatttgtttc ctttgatcgt tacttgtttt gcaatttgtc gcatctcatc cattttgccc
    44401 atgtagtaat cgatcccttg atcatcacca gcacgagcag catctgcacg cttctggtta
    44461 tagaggctca tcagtttttt atacccatct ccgatcgtct gtttattttc caaactcttt
    44521 tctaaatatt ggatggcttg atcgttcaca tacaattcag aaaatttaag tccaacttgt
    44581 tcataaagtt tcgctaattt atgcttatct tgggtagtgg aaatctcttg tttcaattgt
    44641 gtaatctctg attgaatctt ttcggtcgct tctggcgata gggctttttc ttcttttgcc
    44701 agaacttttt tcggttcttt ttcttttttc ttaaaaaatc caaacatcat tttccctact
    44761 ttcaattaaa atgctttcaa aactgggctt aagatccagg catataagag tgctgcggct
    44821 actgtatcta catcggttgc tgtagcattg ttgaatccca tcgaattaaa gatcgttact
    44881 agcaaagcgg gcaataatgt aataaagaaa ccatgagcaa taccgccaat gatcgctcct
    44941 cggcgtccgc caactgcgtt gccaaatatc cctgctgtcc ctccggcaaa gaaattggtt
    45001 agcataccag gtaaaatcat cgctaagccg aacatgggca aagtaaacat ggcaataatc
    45061 gtaccaatcg ttgtcgtaat gaaacctaaa atgacagcat ttgggctata aggaaagaaa
    45121 actggacaat ctaaggcagg gatcgcatca ggaactaatt tcatagctat ccctcgaaat
    45181 gccggcacga tttcacctaa cagtagacgt acaccagcta gcaatacata cacacccact
    45241 acgaattgga tggcttgtaa aaaggcaaac atgatatagt tttgatctcc tgataattca
    45301 gaagcgaatg gttcgcctgc aaataaaaca gtgatgatat atagcgggac catcacgacc
    45361 atgacagaca aataagtatc ttgcagaaat tcgaaatgtg tcggcaactt gatatcttcg
    45421 atcgactttt tattttcgcc tttctcacca aaaagcttag caacaccggc ttcaaataag
    45481 tacccgatcg tacaaaaatg acctaaagca atatcatttg atccagtgat tttacgaatg
    45541 atcggttgcg ctactgccgg catagcaatg gcgaaacaag ctccgataaa accaccgacc
    45601 aagatcaata cgatccctcg cagaccggca aaatagccaa agactgtcgt catcgttgcc
    45661 atccataaaa ttgcttgacc agttaaaaaa atgtacttcc attttgtgaa acgagccaaa
    45721 ataatattga atacaaaaat ggctaagaac gtcagtgcaa tatctctacc taaacccaaa
    45781 tcattcattg cttgaccatt gatagattca atagaaggga tgatcccttg catatgaaat
    45841 ccttcagtaa agattttccc gaaataagtt aaacttccaa cgatgatgct cgaaccggca
    45901 ctcaacactt gaaatcctag gagtgtcttt aacgtgccag agatgacttg tcctgctgat
    45961 ttcttctgca gtagtagacc caacatagca atcaatgcaa tggtgatcga tgcctgagtc
    46021 aaaatatttt cgatgataaa attgataacg cccatgtttt taccctcttt tctttttgta
    46081 tttagataac tcccttatct tgcagaactg gggtgatttt ttcttcaatt tcattttttg
    46141 aaacaatatt tttcaaatag atcatcgccg ttttaggatc aactgcgaac ttttcgaact
    46201 gcgaacgaaa attttctgct gtgatgatca catctggttt catggaaact gcggaagaaa
    46261 tatcacaatg gtccagtttg gcttctactc ctaatttgtt caaaacatcc tcagcagaca
    46321 tctgtgctgc aaaactactt cctaaacctg caccgcatac gaataaaatg ttcaatttgt
    46381 tcatctttgt tctcccccgt atcatttatt atttctcaac tactgaaaaa agcagttgtt
    46441 tgaaatcttc gatatttgtg cattcaatca atcgatccaa cttctcttcg ttgttgatca
    46501 attcaattag ttctttcatg atgttcagat gcgagtagga gtctactgct gccaaacaaa
    46561 aaataatctt tactggatcc atttcaggat taccgaaatc gattggttgc tcaatcgtag
    46621 ctacgctgac tcctaattta ttgaccccat cttctggtcg ggcatgggct agtgccatgt
    46681 gtttgccaat cacgatatac ggtccgtaat cattcactgc acgaatcatc gcttcgacat
    46741 agcgctcttc gacaatgttt tctttaacca atggtctagc agctagttca atcgattcct
    46801 cccaagtagt ggctttttct ttgatcatga tattgctgtc cgtcaaaata tcttttaaca
    46861 taggctggat ctcccttttg ttgatttcta aattgtttgt ttcgaataat ttttctaact
    46921 tgccatagat gattcgatct actcggccac cactttcttt catgacatct attatttgag
    46981 tgaataactc cgtcgattca tgactgttag gctctaaccg ctgtagttct tcatttcttt
    47041 tcaaaaagtc ttctataacc aagatattcg tctcagttaa aatcggatcg acaactaaaa
    47101 gcggcttatt tcgataattc aattgaaagg tgctgaaaac cagattgaca tccaatttat
    47161 ctactaattc gatttctttt gaacttaaaa ctgcagtaat ctcgatctga ggaaactttt
    47221 ctttcagatt ctctgctaac agatttccag tagccatccc atggttacag acaacgactg
    47281 atttataaac ataattcaag tctcgcttga ttacactggc gatcgtcgaa aagtggatga
    47341 caagaaaagc tatctcgtcc tccagtatct tgccaccaat tacttcttcg atcgtaggaa
    47401 caaaatgagt gactgcgcgg tagattggga aataatttgt tcggatgttt tctttcaatg
    47461 gattcatgac ttggatatga ttcttgattc ttacaatcag tgcagccatg tgcttataga
    47521 gattttcgaa taaagcttct tcctttagat ggaaaggtac gtgtgtctcg ttctctacaa
    47581 attggatcaa ttggatcgtt agtaattgag cttgtaccca ctcgattgaa ttggagatat
    47641 ctctagcatt gaacgtctca atagtgaaac gaagataatt tctttctact tgcgggacat
    47701 tgtccaattg aaattcctcg atcatgtggt caataaatgc agaaaagcta ctgtctttta
    47761 tttctgtatt tttccaatta atggcagaga taaattcatg tttcctgatt cgctggatcc
    47821 agatcaatgt aaaaagcagg atttgttttt tataaatatc atcttcttgt ttcaacaact
    47881 tattggaata gatctcctgt atttttttga tttccaccaa aggaaaataa tggagaaaga
    47941 ttttttgagc cggtgttaat tgtgcatctt gattcataaa gaagtcggtc attcccagat
    48001 tctgattgat aaaatcatag atcatcgtac ggatagatcg ttctgaacct ttataaacca
    48061 gtccttgctt tccataactg acgatctcta tcccataact gaccagtgtt gctcgtaacc
    48121 gtctcatatc ttcatctaat gtacttttag agatttgaaa ttcttcttct tttttgttta
    48181 gatggatcgg gattcggctg taagcaacgg ctaaaactag atcaaaaata cgttcgcgcc
    48241 gattcaaaaa gccgtctttc acatctttta tttcagtttc taatcgagct tgcttttcct
    48301 tttccagctt caacaaaaaa cctttgttgc gaattgtacg gatctccgga agctttttac
    48361 tgctcaacca gatattcgct tcaagaactt cctgacggat cgtccgctga ctgacattga
    48421 actcacttgc tagatgtttt gcttttactg gatattgggc tgtcatgatt ctgtgaagta
    48481 tttcaattgt tcttgttttc atagaaatga tctccttctg atttcaagta tatggttccg
    48541 cttacataat aaaaagtaga tatttctgcc acttgaagtg gaaagaaagt aagcaaagca
    48601 aacaaaaaat aagccatatg ctttttcatc tcctcaacga aaaagacata cgcctattat
    48661 tacaaaaatt ttgcccatct atacaaaaaa gaggttgtga aaaagctgtc ctgcatcaag
    48721 taataagaac aactaaacta aaatagtgct tcctattttt cgtttggttg ttcttattat
    48781 cgcagatgca agcttttaaa caccatttag tggagaggtt gtgacagaga tgttcagcct
    48841 tgagcgataa gaagcgattt tgaaaaatcg cttcccatat tttacaaaat cgtgccttat
    48901 tgccgatagg ctatctctgg cacaccgttt attcagaaaa aggagctgcg acaaggcttt
    48961 tgtcacaact ccgttcataa atatttcctg tcaatccagc ataatcggct gaataaaatc
    49021 ggcttgccat cttttttctt tctcagaaaa atcaaaatac catatctgag aaaaatactg
    49081 tcgttgtgtc ttacttcctg agatcaatcg cccatctttt cgatcgactg aataatcaca
    49141 gcatctgaaa tcaattcgga tggcaaaact attttcgtgg atctgtcgat aatttcctac
    49201 ttcctgaata gttatttttt tagtatgatt tcttacaccg tctgctttgt ttttttgcag
    49261 aactttctga tgttcggcaa acagcttgtc tgtataacag cttctggctt tttcaggagt
    49321 ttcttcttcc caagcggatt ggatcttcat gaatatcttt tggatttcca gaaactgtgc
    49381 tttcttttct ttagccgttc ctgacatgcg ggacaatatc tccgctttca gccttttctt
    49441 ttgtctttta ttcttgacga tagaaaaagc agaaacccct cctactgaca aaacagctaa
    49501 tgcaagaaat cccgtttgct cataactaga aggacctgta cctggaccat aatacccata
    49561 agaatctctg ccgtaagaac gactgccaaa ataactgccc ccatatgaac gaccaccaaa
    49621 tgaacctctg cccgaacttc gaccgctaga tgtacctcca ccatgaccac ccgcgacagc
    49681 gaatccttgg gtcggcagag caaacaaaca taggcccact aacaaaatga ttgctaaata
    49741 attgattttt ttcattgtct tcctcgttat cttttattac aaaaaactat ttttatgata
    49801 gccttgctaa aaggaagagt caataaccag atgcataaac tgttttttta gcaattttgt
    49861 cttatttagt cattgagtaa catcggacaa atgtatgtgt cggcagtcca taattcctct
    49921 atcttcagca tgaacaagct tgcagacaag agatctgcgc ttcctccagg agagatttgg
    49981 ttttcctgac aaaagtgcaa cagtgctgta aatggacgat ttggtaaagc actttgacta
    50041 gcagcatgag caagtttttg catttccact aacgttttct gatcactgcg atgcaatacg
    50101 catgtgtcat ctagcgaact catcaaaact aacaacatat gcatttgttt ctgtacatat
    50161 gaatcattat ctagctcctt agctgcttga attgcaagcc tgatatgcgg ataccctaat
    50221 atcgcttctt catatgcacc atttacgcca tatttttgct tcaccctatg accatgagtg
    50281 gtttttttat gacgatattt tgtatcagga aaagcagcaa gcttgctgac atcatcaagt
    50341 attttcgata aagaaaaagg ctgttccata ctgatttttt gtgcaatgac actgatcaat
    50401 agccccattg cccaaatcgc tcctttatgg gtattgatgc catttgtagc aatcagcatt
    50461 gccttttccg cttttcgccc aatctcagca attctttctc ttaactcctg atcaatagca
    50521 tgatgccatg ctatttgagc catttcttca aaaaaaggag ttagcgtctt agcagactta
    50581 agaaataaag catagtccat atcggaatgt gcacccgcat ccagtgcatc cactaatcca
    50641 ggttttggac ttaatgttac ttctgcgatc aatgcttcct ctaccaacgc agcgagttgc
    50701 tgagtcactg ctttttttcg ttcgtcattt atcatgacac tcactccttc ttcctactat
    50761 tacttgctga aacctttttt gatagctacc caaatgatat gaagtaacca gcttaaagca
    50821 aatgcacaac ttgccgtcat tagataagct acaagaatca tgactcctga aggtaactgc
    50881 agccaactat ctttaaacaa taataacagt acttggaaaa caaatacatt ggctaaatac
    50941 gtacgataag cataaacaga caaccatttg aacaatggca attttggcga atcgtttaca
    51001 atcattttgg aagcgcctat gaagacagca aagatgatga ctaaactgta taaactttgg
    51061 atcgtattca agtaaggtgc attcgcaaag ctcaagtctc ctggatgtgc gagcaatgaa
    51121 cggacagaaa agaacgcgat aactaaggca acaggtaaga aaagataacg tactctgtcc
    51181 aaatattgat agactttttc gtgataaaca aatgcggcta ccccataaat catgaaacta
    51241 gcaacaaacc gatctaataa gtaccagctg tcatgataag gcccagtcaa tacttgtgtt
    51301 tgatagaaca gataccatgc gacatataaa atcgttgaac caatcaatac tggccataca
    51361 tattttttat tagcaaatac tttgtaaccg agccaaacaa aaaacggcat gaacaattgg
    51421 atctgcagca tcataacggt ataccataaa tgaggcgctc catcacctgt gacatatttc
    51481 agtaaaaagc ttgcagtatc cgtatacgga gtttgttgtt ggactgctgg aaatagccaa
    51541 agataagccg tcgtccatag aagatacgga acgactagtt caaaaaactt ttctttcaaa
    51601 aattcccaat aagacaaatg ctgacttgtt tttaccatat tataaacaat tgcaaaaata
    51661 aacattggtg ctgtgtattt aacgatgacg taaaaggtac caagaaaagc tgtatttgtt
    51721 gcgctgtggc tgtttgccaa agcaaagctc aatatcgttt gcatcataac agccgttaca
    51781 gctgatactt tctggaagtc acttacgttg attttgattt ttttgttttc aaacatctct
    51841 ttctctctct ttttctttat taccaaagtt ctttggttaa tttaggtcct tcgactgttt
    51901 tcaatagaat ttttttctct ggctctctca aatactcttt tagtgaaaaa ccgccttgcc
    51961 gagtcactac ttgggtatcg aattgctcaa aaaaagcagg atgcgattga attacctgaa
    52021 ttggcaattc aatcggtgaa tttgcgtaca gcagcaaatc aaaatcactg gtttctttta
    52081 ctgccggaat cccagtcgat aattcaaatc ctaagctgcc gccgattccc catttacatc
    52141 ctgataatat gtttctagca gcatgaaatt gctgataaac aggataatcc atgattttct
    52201 cttgtctata cgattcttgt tcgatgatgt cccacggatg aatgacttgt ttgacggcat
    52261 gttttgagat ttctgttgac catctctgat tgcgggcagg tccacgtaaa ccaatcggta
    52321 gtatttctgc gtgatccgtc gacgcacgac gaactgttcc gaacatcttt tcagttagaa
    52381 cgacccattc aggcaaggtg aacccttcta tttcatgttt atcaaaaagg acaatatcat
    52441 gtgcttgaat cattttttat gcatcccatt cttcgtccat tttggcacgg actttatttg
    52501 tttcgacacg tccgaatgtt ttggctgttt cgtttgtgta tcgatttgtc agcatcgtgt
    52561 catttgtatt gcggacatct tgaatggctt cattgattgc ttcgatgact ttgctgacat
    52621 tttgttctga agcagcttgg tcggtgatat cttctaggaa atgatagatc gctcctagtt
    52681 ttgtataatt attgatatcg taagcgatag ctggaacttt ttcagcagct gcttcgattt
    52741 cagcaaccga acgttttgtc acacgtgcag cactttcttt agacatcgct tggacggtaa
    52801 tttctttatt gtttaaagca atcaagcggc ttgattgtaa tccatgtgct aaaaatgcac
    52861 ctgaaatagc atttcctgca atcaatccaa taactggatg tccagcttga cggagttttg
    52921 cataagcagc agcactatta gccaaagcca catggatacc gatcaattct tcgttatagc
    52981 cgtatgcttg gcttggtaca tcgatcacaa cgatgattgg ccgtttcact tttttgtctt
    53041 tatcttcttc gtaaacgtga tccaaaattt gtcccatgcg gaaaccttca actaaaccaa
    53101 cttcaccgtt tcgtacacgg tacatcgggt ttttaggatc aggtacgatt gatgtcacga
    53161 tggcttcttc tatgaattta cttgatttac cataatacac agtactaata gaagaagttg
    53221 gatttttcat gccagttagt gccgcaaacc aatcgtaacc aacacttgct gcagctggtt
    53281 catttccttc tgctacttct ggtaagtcaa ttgattttgc ttgatggtta gcaattgctt
    53341 cattgtaatc gtcaatggcc attggttttg aaagatctaa agaatcaagt aatgataaat
    53401 aaaatgctga gctttcactg cgatgcgtgt cttttcgttc gtccattgct gcgatgacag
    53461 cagctttgat tgcttctaca ctatcagtca ctaattcatc aatgattttt gattctaccc
    53521 gttgacgaga tcctaatgta ttccaaatca agtctttgtc actagaatca aattctcgaa
    53581 cgcctgcttc ttgttcaata acttctggtc cattcaaacc gactctcgct ttttttgttg
    53641 cgattaaata actcattaat gctgaagtaa tcgacatacc gccaaatgat cctacacgtc
    53701 ctggaatcaa accgatgact ggtacatatt gttttagagc aatgattaca tttccgattt
    53761 ctgaaataga taacagtccg tagtttgctt cttgcaaacg aacaccacct gtatctagta
    53821 caatgactgg aaagatctca tttccttttt tattttcttc taacacatgt tcaagtgcag
    53881 caacgatttt tgcaccggaa acttcaccga taccgccacc ttggaatttt ccttccatag
    53941 cgattactac tgcttgtttg ccattgatcg tgccacggct gacaacgatc ccgtcatcac
    54001 tttcagggac gattccttgt gctggtaaac ttggcgcgat gatttgatcg aatggatcaa
    54061 tcaattcacg tccattgtca agtagagcgt tcactcgttc tctggcgttt aattctacaa
    54121 aactattttt catctgaaag ttcctccatt gcttgcgtca atcgtaggta cacaactcct
    54181 ggtgtagcac cgaagtcatt gatcacgata tctgctgaaa ttggataacg atcaaaaaat
    54241 ctcgttaata cattgttcca tacttcgccg aagccatcgc ttcctgtaca aatttttaca
    54301 gtagattctg ttttttctgt tggaaacatc aagatttcca aatctcctga accgaccact
    54361 cctacatgga ttttcttatt gatcggctgt ttcgttggat atttataagc taattgttcc
    54421 atggatctct cccctttttg taaaacagag catacacgtt ctgcttattc gtctttcttc
    54481 ttccatctgg gtaaatggcg acaaaaggtt tttctcgcca attttatgac caagttctga
    54541 atttcattgg tggttcatac aggccatctg accattcgat caaatcatcg atggtttgtg
    54601 cagctaataa tgaacgtttc gcttcactac gtttgatgcc tagatcttct ggtaatttca
    54661 cgatgccggc tgcacgcaag ctatctagtg attctttcgt gctagtcatt ccaagaggtg
    54721 taacaccgcc aattgctgca attgctgctt gtcgttcttc ttttgttttt gctttgtaca
    54781 aataagcaat tccttcttct gtcacgatat gtgtagtatc ttcgctataa atcatcactg
    54841 gtgcattggc taagcctgct tgtttttgaa cagctagtgc atctaattct tcgacaaaga
    54901 ctggtttttt atttgaacca tatgtttcaa ccatttgaac aactaatttt tggcctttcc
    54961 ctaatggatc atcattgtcg cgaagtgatt gccatgctgg tgtagaatga cgacgaccgc
    55021 caggattatg tcccatgtta ggcgcaccgc caaaaccaga taaacgtcct tttgttacgg
    55081 tagaagagtt tccttcgtaa tctaattgca aggttgaacc gataaacata tcgatggcat
    55141 attgtcctgc agcttgtgat aatgttcggt tactgcgcat cgtgccgtct ttaccgacaa
    55201 aaaagacatc tgggcgagca gcaatatatt tttccatacc aacttcgcca ccaaaactat
    55261 ggatgctttc aacccaacct gattcgatgg ctggaatcat cgttggatgt gggttcaata
    55321 cccagttctt cgcgattttc ccttttaacc ctagtgattc accataagtt ggcagtaaca
    55381 attcgatagc tgctgtattg aatccaatac cgtgattcaa agattgtacg ccgtgttctg
    55441 cgtagattcc tttgattgcc atcattgcca ttagaatttg caattctgtg atgttttgag
    55501 gatctcgtgt gaataaagct tctaattgat aaggtttatc tgctttcacg acaacgtcta
    55561 cccagtcacc agggatatct acacgtggta aagaatcgac aacttcgtta acttgaacga
    55621 tcacgatacc atctttgaaa gctgcagctt cgatgattgt tggtgtttct tccgtattga
    55681 aacctgtgta caagttgccg tctttatctg ctttatctgc agctactaaa acaacatttg
    55741 gaatcaaatc gatgaataag cgtccataaa gttccaaata agtatggata tcacctaatt
    55801 tcattgtgcc gtcttcaatc atttgggcga cacgcaagct ttgtgcacca gcataagaga
    55861 aatcgatctt gcttgcgatt cctttttcaa aaatattcaa atgttctggt cgtgagatac
    55921 tagacatgat caaatgcaga tcattcactt tttctgcatc tactttttca agactttctg
    55981 aaagaaaact tgcttgtttt tgattgtcgc cttctaatac aactttgtcg ccgggagcaa
    56041 tcagtttttc cattacttct acgatttttt cagtttctac atacttgcca ttgagcaagt
    56101 tgctgatttt ttccaatcgc tgcgcttttt tttcgcgttt agaagcccag ttgcggtttg
    56161 gtttttccat aattagtcat ctccattttt gatatagaaa cgtggcgtca tcaataccat
    56221 gttggtctag attgatcgta cggatccctt tatctacacc aaattttgta tgaatcagct
    56281 ttgtcaaagt attgccgggg ggaaattcaa tcgtcagatc cattcctaat tcttttgcca
    56341 agtccatcat ttggttccac tgcacaggga aagctaggtt ttccaacaaa tctttacgaa
    56401 tctcttctgc gtcctgagtg gctcttccat ccgtattttt tatatacaaa catctagcat
    56461 cagatagatg gacagactgc atatacggct tgaatttctt gaccgtatca ttcatcaaga
    56521 gacagtgaga tggcacaggg actttcagca gcttcgctgt ttgcgcttgg tgccgtttgg
    56581 cttctgccaa cgtaacggat aaaccttcga tactcccaga taacgtatgt tgcatcggac
    56641 aattttcatt tgacagataa actggatggt caggatcaaa tgtttttgct acaatttcct
    56701 cagcttcgct tctcgtcaca cctactacta cgcccattgc ataaccgctt ggataagctt
    56761 ctttcattaa gactgcgcgg tgatagacta gttccgctgc attctcaaat ctcaaagatc
    56821 gacaagcaac agctgcacaa aaagcaccaa tcgaatgtcc tgctgcaata tcaggctgaa
    56881 taccgttttt ttccatttca tctaaataaa atactgcttt tgtcagtaat gctagctgga
    56941 taaaaaccgt atcttgatag ttttcttctt tatcaactaa ccgatacccc gtcacatttt
    57001 ctaaacgttc catgtacatt tcagggatat ccgctaacat ccctaacttc tgactgcctt
    57061 gtccaggaaa taagaaacct gtactcatga gcctcgcctc ctcagcactt actttttcca
    57121 ctgctatctt agtcaatttc tgctataata aaaaatgcca aaaaaagaaa aaaccataac
    57181 aaaaaggtat ggatgggatg gataattatg aaattgcttc atctgcagta ttttaaaaaa
    57241 gtattcgaaa caaaaaatgt tacccaagca gccaaagaat tatttatttc tcaacctgcc
    57301 ttgagccgtg cgatcaaaca tttggaaaac gaattaggtg tccctttgtt ttaccatagc
    57361 ggcagaaaca ttgagacgac cgtttatgca gaagaatttt atccatatgc agtcaagaca
    57421 ttagacacat tagaagaagg aatcaaatta ttgtcttcgg tcaatgagaa gatcgttact
    57481 tccgtcatat tgtatttaga ggtagcctct gtttctattc cgaacttggt ccgaattttt
    57541 atggaaaagc atcctgatat ccaattaacg atcatgcaac atcatttacc agatgatatt
    57601 accgatcctg tactgtacat cacttcggag atgaagcctg gcatgaccaa tattcctatc
    57661 atgaaagaac ctgtttatgt cgccattcct aagaaacatc ctcttgctaa aaaagaacat
    57721 ctgcaattag aagatatcca acgcaccccc atcttgatgc tgtcaaagag caacgccttc
    57781 cgtcatacac tggatgcagc acttgaagcg aaaagtatcg aattgacgat cagttcgacg
    57841 acagatgatc ctgcgacatt acgttctatt gtcaagcaag gattagctgt tagctttttc
    57901 ccaaaagttt cttggtctta cgataaaaat gatcctttcg tcttgcggga aatcaaagat
    57961 ttgcccttga cacgaacaat ttatttatct tctagcttca cagaagatca tcctttgatc
    58021 aaaatgattg caaaaacgat gcgggaattt tatttaggaa aataaaaaaa aaagagctgg
    58081 gacaaaattc ttgtcgcagc tcttttttcg aacaaacggt gttccagaag taatttctta
    58141 gaaaataagc cgaaatttcc caaaaatttg agaagcaatt ttcgtaaatt ccttcttatt
    58201 tcttgaagct aaacatttct gtcacaacct cttctctatt gtcctagaca ttcattgcgt
    58261 tgatttaaaa cttccatcaa tcaaatctgc tagttcatct agcttttcta ttttacgtag
    58321 atcaatagag atccaatgtt ctttattcat gtgataggct ggaaaatacc cctcttttcc
    58381 tcgcaaaatt ccgccaagtt caggatcgac cttcaaatca agaatattga tgatcctatg
    58441 gtcacttgca tcatcataga ttttttcttc tggaacagac atcaggaccc caaaccattt
    58501 tttgcttttt tgatgtctga atacgcaata atcaggaaat tttttaaaaa tatattctgg
    58561 agacaaattg tatgtttcat tgatgtgatc gattagttct tttttcgtta gcatctgctt
    58621 ccatctcttt cttattgatt cgctttattc aaagatacca cgtaagaata gaaaaatgaa
    58681 tacaagtagt tgctaatcaa atacttcgat atttttcttt tttatcaact cttaaatgtt
    58741 caatccgcct gtgttggtct tgctaccatc tactattaaa atgtttatta ttgtttgccc
    58801 acctattttt tgattttagt ggtatcattt ttcaagttca tgatgaaatt cttatcatca
    58861 gtaaatgctc cagaaaaata aacaatgatt gaaaaatcag ttgaaacttg accaccgttt
    58921 attttctccg tattcttaga atagaaggga gtctgattga tgtattcact aatgaaaaaa
    58981 atcattaccg aaaaagatat tcgacgtcat gtttctttag tagaacaatt gctgaatcat
    59041 acaaagataa ccgtaaatga attagctgaa atcataggga caaccgaacg aacgattttt
    59101 tctgaccttc aatctattcg ctctcagctg cccgaaggct gggacatcat cagcgatcaa
    59161 gcaggaatca gtttgcaaaa ccagcaaaat ttattaacaa atgacctttg ggagattttt
    59221 ttcaaacaat cagtcagtgt cgaactgctg aaaaatctgc tttttacaaa aaaagttgct
    59281 gtccctgatt ttctagccga ccatgggctt tcttatggga cattgaaaag acatgtgact
    59341 aaaatcaatc agcgtttagc aagttacgac ttgcagatcg atttgacgaa atatacagct
    59401 tgtattcttg gaaaagagcg tgcgattcgt actttttatc atcgattgct gattcctttc
    59461 actcataaca actatttttt cgaggattat tcgatccatg aatcccatta ttttcaattt
    59521 ttaagaaacc tcagtcaaac tgaactagcg gttgaaacag aagagatttt cggaacatgt
    59581 tggttcttta tcaatacgat ccgtataaaa gcgaattgcc gattagattc ttctatccat
    59641 accaacagca cactctcctc cctgtatgac tctgcattga aaaaattgta tttaacggaa
    59701 ggtatttatc ttaaagacac tgagctttct tttgcttctt tctgctttct ggaaagttgg
    59761 aattacaaca ataactatgg acaagaaacc gctcgctgcc tgcatcattc tccattttta
    59821 gaggtcctcg aaacgtttgt agaggaacta gcttcagagc tgtctcttga tcaactaaaa
    59881 aaaacatctc tgactgataa cttggctctc ctcatattaa aatatcatga atcgccgata
    59941 ttgattgaag cattggaccg tcaataccat cgttttttag aaacatatga tcagcaatat
    60001 gcacacttgt atcaacagaa agagaattta ctgaacgatc taaaaaaaga aatagaaatc
    60061 aatgaaccaa attactttct ccaactcttg tctctactga tccaacaaac gattttttct
    60121 atcaaaccga atttgttcaa tgtctatttt attttccaag gagaaccttc atggaaggcg
    60181 ttcttgcagc aggaattaaa agattactta ggaaaacgtg tctgcttctt acctatcgaa
    60241 ctaaccgatc tttccactat ttcttttgaa aaaacagata tcttgatttc caatttccct
    60301 ctagattctc tagatatccc tattgtatac atttcttcta ttccaacgaa aaatgagctc
    60361 aatcgtttga ctgaactcac tttcaaaact tttttatagt aacggctagc gactgtattc
    60421 tctagctgtt ttttcttttt tgcgaaacag tttgttcatg atcccttttt ctatttctac
    60481 aactaagaat agaagaatca catttgctcc aatcaataac tgttgtgtca tcgttaaact
    60541 tactgtaccg atcagctgct ggccgactgg tagaaaaata accatccctt gcaataaagc
    60601 aaggatacct aatgaaagaa aaagcgcttt gttttgcaaa agaccttggt tcaatgacgg
    60661 cttggacaac tctctgcaat tgatcatgta aacagcttga gctaagacga tattttgcag
    60721 aagaatggtt tgctgtaagc tttgcccttc aaactgcata gccaataaat aggcaggaac
    60781 catgatcagt agggagacat agatgatccg aaacaaatga taaccagata ggattccttg
    60841 ctttggatct cttggtgggc gcttcatgat ttctggatct ggcgactcga accctagtgc
    60901 ataagataaa gtgattgtcg ttaccatatt gacccataaa atctgtactg gggacaaagg
    60961 tagcgggcga ttcagcataa gtgcccaaat caagatcaat ccttgagcta atgcagttgg
    61021 caagaagaaa ttgatggttt tttgcaaatt atccaaaatc cgccggccct cttttacggc
    61081 ttttgcaatc gtatggaaat tatcatctcc taaaaccata tcagctgcct gtttgcttac
    61141 ttcactacct ttgattccca tagcaattcc tacatcggat cttttcaaag caggtgcatc
    61201 atttacgccg tctccggtca ttccgacgat ttctccattt ttctgcaaag ctttaacaat
    61261 tcgcagttta tgttctggtg tcgttcgagc aaagacatcg actattggca cttgctgaat
    61321 caactcttca tcagacataa gatccaaatc gatcccttct aaaactttgg cagtatgttt
    61381 taagccaatt tgttccgcaa tcgcttttgc tgtgtctttg tgatcccctg taatcatttt
    61441 cactgagatc cctgcttgtt ggcattcctt tacagctttg actgcacttt cttttggcgg
    61501 atcgatcaat ccggcgatcc ctgcaaaagt taattgggtt aaagtctcat gcgtgagttc
    61561 ctgtttcgaa tctacttttt tataagcaaa tcctaaaaca cgctgacctt ttctcgcaaa
    61621 ttctgcagct gtctgactcc atgcttcttg ttctgcagaa gaaagagttg atttagcaaa
    61681 taatacttct ggtgcacctt tgacgtaaat caccgctcct ttttcctccg catgcatcgt
    61741 tgccatatat ttgtattcag aactgaacgg aatctttgct tctatttttt tcaaaggtag
    61801 attggctgtt tctgtgtgtc gaatcagcgc aacttctgtc ggattgccac ttaaattttc
    61861 tgttttctgt tcttcttttg tttttaattc ctgacagttt ttcataatgg acaacacgca
    61921 ggcttcttct tttgcagcta catccacaac tgtcatttca ttttttgtca atgttcctgt
    61981 cttatctgaa cagatcactg tcatagaacc taatgtttct accgaaggaa gtcctttgat
    62041 gatcgccttt tcttttgcca tttcatgtac tccaacggat agaatcatgg tcaaaacagc
    62101 tggcaatcct tcgggtacca ttgacaccac caaagcaatc gtagccgaaa gaagaatatg
    62161 ccaatccata ccatatcgaa atgtcgtaaa aataactaag aataggctca aacaaagaat
    62221 gccttgaaaa atttgtttgt ttaatcggtt gattttttta atcagaggcg tcgtttgttg
    62281 ttcgaccgat tgcaatgctt gattgatttt accgatttct gtcgtgtttc ctgtttctac
    62341 aacgacaccg actgcagaac cagattgtac aagcgttcct gaaaaaccca tatttttctg
    62401 gtcgccgatc gattcttctt ctgtcaaaac ggcatgactt ttttcagatg cttctgattc
    62461 tcccgtcaaa atcgattctt ccactaataa atcatgtgct tcgattaatc ggatatctgc
    62521 tggaacgaca tctccggcac gtaagacaat gacatctcct tttaccagtt ctttcgcagg
    62581 gattttttct tgcatcccgt ttgatagtac tatcgcttct tgtcccatca gctgcttcaa
    62641 accattcaat gattcttccg cttttctttc ttgccagtaa ctaacgagtc cattgacgat
    62701 cactacgaat aaaataatac ttccttcaat atattcacta gaagcaaatt tcaaaaaaga
    62761 ggcaatgatc aacacgatca tcagcagatc agtaaaatgc tttgctattt ttttccatcg
    62821 ttttgtctgc tgccttgctt ttatttcatt atatccttga tcagtcaggc gtttctgtcg
    62881 ttcttcttgc gacaagcctt ctgttgatgt ttgatagttt ttcaatacat cttctaccgt
    62941 caatctgtac cagttcatcc tatcccctcc tgtttaattg atactgttat tatacgcagg
    63001 gaagtttttt caggcgtatc gattatttca ggggggtctg aaataattcg ttttgcaaaa
    63061 tgtatctggg cctaactgat atttctattg cttattcttt tatatacaaa atttaagaat
    63121 acaaaccaga taaccaataa aaaaggaata aagcgtgtcg tgctttcgaa taacaagctg
    63181 aaagcaattg aagtaaaaaa caccaacaaa gcaagatctt tatatctttg tgtagtgttc
    63241 cgtttctttt ctttaataaa ttgaacatgt gcacacaaga tcgaagacca cacaaataga
    63301 aaacaactcg ttgtcatgcc tgccaaaagc tgaaaaaaca atcgactatc agctacaaaa
    63361 aaatgtagac aaagaccggc aaaaaataac attcctgtaa ttaaaatacc gtgtaaaggt
    63421 acgcctttct tagaaagcgc acaaaaccaa tggggcaaac ttttttcttt tgctgtttga
    63481 tataaaatcc tgctagtact gtagactgca ctatttgctg aggacaaaga agcaaccaaa
    63541 atcattagat tgacaattgc tgctccgcct tggcaatgga tcacttgcag catagtcact
    63601 aaaggacttt cttttaaatc taaacaatgc catggaacaa caaataaaat cgacaaaatc
    63661 gttcctatat agaaaaagag aatacgccaa ggcagacagt tgattgcttt tttcaaattc
    63721 ttttgcggat cacttgtctc gccaacggtt aagccgatca tttcaattcc agcaaaactg
    63781 aataaaacca taggaaatga gactaccatt ccagcaaagc caaacggtag taattcatcg
    63841 atctgtccaa aattttcttt gattccgata gactgggtat gaaaatctga gacactcaat
    63901 cctataccca ataagataaa aaggaaaatc cccaagatct tgatgattga gaaaaaagat
    63961 tccaattcac caaaccactt gactgcaaca aggttgactg ccattaagat cattagtgcg
    64021 ctacctccgc ttatcaaagc tggtacatgt acaaaccaga aatggatata caatcctatt
    64081 gctgttaatt ccgcaagtcc agctccaagc cagcaaagcc aataagtcca attgacaaaa
    64141 aatgcccact ttttgcctaa ataatagtca acgaaatcac tgatagagtt aaatgtacta
    64201 tttgctaaaa ataaatcacc catggcccgc atcaaaccat aaatagccaa accgcatatc
    64261 aaataaacga gaataacagc tggccctgct gatgcaattg cctttgctga acctaaaaat
    64321 aatcctgttc caattgcgcc acctaatgcg attaactgga tatttcgatt agttagagtc
    64381 cgtttcattg ccggtttttc catcaagttc acctttttct ttttcaagca gcatggcgac
    64441 ttcctgttcc caagaaggtt tctttatttt ttcaatacag agtggtacta caaacaaaat
    64501 gacactgatg gctgtgactg caattagatt gatccatgtt ccagctttca tcgtcagtcc
    64561 gacagaaaat ccgattgccg caaataaaac aataacgaca gtccaaactc caagattgct
    64621 ctttttctct ttttttccaa ttctaaatgg tcgattcaac tttgcatgtg tataacgcaa
    64681 tctcaaaact gcgatcccca tgatgacata gacgatacag tagataacag tagttgaatt
    64741 tacgagcatc aaaaatgctt gattgacgcc aggaatcagc aaataaaaaa gtgcaaagat
    64801 tgagataatg acagactgag tcaaaataac ggatttggat acgtcaaatt gattcgtctt
    64861 ccaaaaattg aattttggtg gatacgcacc ttttctagca ctttctgtca ctgtctttgc
    64921 tggtcctgag gcccaagcag ataattggac tgctacacca atgaagacaa gtaaactaaa
    64981 cagattcaca ataagatgtg gcaaaccaag aatttggcaa taaatcgaaa tagattgcgc
    65041 gatattattc aattccattt gtccttttgg tacgacattt gctacaacta aagcattcaa
    65101 aatattgacg aaaaatataa aaattaacgc ggcaaatact ccgcgaatat acgttttaac
    65161 tggattttcc aatcgagtga tatacacaga ggacatttcg ataccagtaa aaataaacat
    65221 gatcggcgca aaataaacaa atgaggatgc agtcgtagta tctggtatta atttgtccca
    65281 tgaaaaactg cctaatgttc cggttggtac gatcccaact ttgatccacg cagcaaaccc
    65341 taataagagc atcatcgtca aaggcacgta caatcctaac caaacaccga cttttccgcc
    65401 gatttttgcc atatcaaatt tcaaattcaa aaaagtgatg atccaataaa cgactaaaat
    65461 gacaactaat gtaaatttgc tgttcaaacc aagcggcaca ttatcgataa tattaccaaa
    65521 caacggagcg agtgctgaag cgaccatcac catcccagga aacatttgga cccataacag
    65581 ccatgagaca acgaaccccc atttttttcc tagagcattc gatacccaaa gttctggacc
    65641 acctttttgg ggaaacattc cagcaaattc accagagatc aatgagattg gaaaagcgta
    65701 caataatact gcaaccagca tgtaaaaaat catcgtccag ctcgttgctg ctacatctgg
    65761 aatatttcgt acacttgcta caagggcgca ggtcattccg ataaaggtca tggtcgtgat
    65821 ttgctttgat gaaccagtat ctttcatctt tattccttct ttcaatagcg acatatgttt
    65881 ttgttttctt ttatttttgt tcaagaacag aaatgacaag gtttcatcga ttcagtacaa
    65941 aacccagtat caccgaaaca tccattgaac gatcttagtg aactgggttt gatacatgaa
    66001 acgaacgatc caacttatag aacgttttat aaaaaagaat atcttggcga ggaatatatg
    66061 aaaaacaggg ggaaatacaa ttgttttgat gaagcaaata attgtctgtt ctccatatgt
    66121 ctcttgttat tctttcacac aaaaatcagt tctattggat gatttcgttt agtttctttt
    66181 ccattgcttt ggcgattttt tttgtataaa aattgaaaat tcgatcatca ttcaaataag
    66241 gagtcatgat agccgcacgt agcagagtga ttttctgttc ttttttccat tcttctttcg
    66301 ttagacccat tctttcaaca aaacgaatcg gagaatcacc gtaatcttct tgtgtaaatg
    66361 tagtatgaga agtaataaac cgttcaccat aaacatcgcc atccatataa gaagaccgat
    66421 cgaacatttt ttcatttaat tcattgatag cgttcaaatc tgtacagcct tgttctttga
    66481 atacccaatt gaccatatta aaatcaggat gattcaatgg atagacttcg attgtttttc
    66541 ctttaacagt aaaagtcaga tgatcgagaa attctctgaa tctttgagct gcctcgattg
    66601 aagccccaat caattgacca tatccggtca cattcaatgg caatacacga tgtgctgtcc
    66661 agactgcggc ggcggttgct ccagcttttg atccttccaa aatataagct cctaacatat
    66721 ctggagcctt tactgatttt tcaaacacat atggcgcgaa ataagaaatg atatttctca
    66781 tatttttatg tttgattacg attcctccag cagcataagg gacatagccc atcttatgag
    66841 gatctatcgt gacagaatcc gcttctgaaa tagctctgaa cccttcatat acctctttgt
    66901 caatcgttac gcagtggtgg aaaacatgat gttcttcaaa gaattcagct aaggaagcat
    66961 acggcacaaa ttctcctgct tcgtttagaa acagtgaacg cgcatagccg ccatatgcgg
    67021 catcaacatg taaatagaaa tagatccctt catcttttaa cctttctctt aattggacga
    67081 ttttatctac actgtctact tgaccttctt ctgtcgttcc tacgacagca accacaccta
    67141 gaattgggat tttttgtcca gctaattcac gaattgtttt ttccaaagca ttaatatcca
    67201 ttcgataatc ctcttgaact gggatagcaa ccatctgatc taagccgact ccgcaaatat
    67261 ctaacgcctt catccaagaa tagtgttttg tttgagggac cagccatttc cctaatcttt
    67321 ggatattttt tccgctacgg gaagaagctg ctttgacctc atccatttct tcgtccgtaa
    67381 agctttcggt catttccaaa atttcttcaa cagataaatt caaaagttcc cactcagaca
    67441 tttttttcac tttttcaggc agcacttcct tgacagctaa aggaatcgat ttgatgcaac
    67501 gggcgtacca taatccttca agattagcaa tagaaccatc tgctgcaatg tgtccccatc
    67561 cgtctgtcat attgaataat gaagcaaaat cctgtcctac ttctgcttcc atttgcgaag
    67621 ttgccataga agattccaat gcaacattat ttgggttcca cagcatcgca tagttgtaag
    67681 ctaataaagc aggcatcaat gtttcagcat tcatttgtcc ccagtaacgg cctgctgaat
    67741 gccatgggat cgatcctgcg cgtaatcgct gactgacttc atccaagacc tctatcatat
    67801 ggtcgcgggt ggctagataa tctggagtga gcttatctcc ttcgctaatt gcaggcatat
    67861 ctgaaggaat ataattttct ctccatccaa gatgttcatc taccatcttg ttcaacaaca
    67921 ttttataaac tggtccattt tcagctttgt cgcctataaa gacggccttg atatccatat
    67981 ctttcatttt tcttccctcc atattttgtt ggtcaatgtc ttgcagatac atgtgtttat
    68041 ctgtaacacc tcttcactat agcgccaaaa atgagaattt tttttttata acatcaaatc
    68101 cacgtagatt tttacaaaca aaaataaata aagtcggatt tttctgataa ttcaacgcaa
    68161 aaaagcgaac aatttttcaa taaatcagtc ttctaaaata gataacctaa aaaaagcgaa
    68221 caaacaaata aaatgactgt ccttcattca ctaaacatat ttttattttt ttat
//
LOCUS       DACGEU010000003        65458 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.003, whole genome shotgun sequence.
ACCESSION   DACGEU010000003 DACGEU010000000
VERSION     DACGEU010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 65458)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 65458)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..65458
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.003"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            146..1009
                     /locus_tag="IXR40_000163"
     CDS             146..1009
                     /locus_tag="IXR40_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAQ4360042.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(1138..2760)
                     /locus_tag="IXR40_000164"
     CDS             complement(1138..2760)
                     /locus_tag="IXR40_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAQ4360043.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            3009..3530
                     /locus_tag="IXR40_000165"
     CDS             3009..3530
                     /locus_tag="IXR40_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360044.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(3716..5446)
                     /gene="spxB"
                     /locus_tag="IXR40_000166"
     CDS             complement(3716..5446)
                     /gene="spxB"
                     /locus_tag="IXR40_000166"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HAQ4360045.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            5611..6429
                     /locus_tag="IXR40_000167"
     CDS             5611..6429
                     /locus_tag="IXR40_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005232914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HAQ4360046.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKHHFAVFGVMSGFIIMMILDVALG"
     gene            complement(6532..6729)
                     /locus_tag="IXR40_000168"
     CDS             complement(6532..6729)
                     /locus_tag="IXR40_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360047.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            6898..7476
                     /locus_tag="IXR40_000169"
     CDS             6898..7476
                     /locus_tag="IXR40_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HAQ4360048.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            complement(8521..9024)
                     /locus_tag="IXR40_000170"
     CDS             complement(8521..9024)
                     /locus_tag="IXR40_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HAQ4360049.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            9383..10408
                     /locus_tag="IXR40_000171"
     CDS             9383..10408
                     /locus_tag="IXR40_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAQ4360050.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            10731..11609
                     /locus_tag="IXR40_000172"
     CDS             10731..11609
                     /locus_tag="IXR40_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360051.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLAGEHIGSGLGILTS"
     gene            12085..12201
                     /locus_tag="IXR40_000173"
     CDS             12085..12201
                     /locus_tag="IXR40_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HAQ4360052.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            13129..13467
                     /locus_tag="IXR40_000174"
     CDS             13129..13467
                     /locus_tag="IXR40_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360053.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            13561..13791
                     /locus_tag="IXR40_000175"
     CDS             13561..13791
                     /locus_tag="IXR40_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360054.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            14191..14562
                     /locus_tag="IXR40_000176"
     CDS             14191..14562
                     /locus_tag="IXR40_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HAQ4360055.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(14836..15528)
                     /locus_tag="IXR40_000177"
     CDS             complement(14836..15528)
                     /locus_tag="IXR40_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAQ4360056.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(15531..16316)
                     /locus_tag="IXR40_000178"
     CDS             complement(15531..16316)
                     /locus_tag="IXR40_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAQ4360057.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            16553..17953
                     /gene="lacG"
                     /locus_tag="IXR40_000179"
     CDS             16553..17953
                     /gene="lacG"
                     /locus_tag="IXR40_000179"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HAQ4360058.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            17978..18295
                     /locus_tag="IXR40_000180"
     CDS             17978..18295
                     /locus_tag="IXR40_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAQ4360059.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            18308..19981
                     /locus_tag="IXR40_000181"
     CDS             18308..19981
                     /locus_tag="IXR40_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4360060.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSAMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            19995..21626
                     /locus_tag="IXR40_000182"
     CDS             19995..21626
                     /locus_tag="IXR40_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016608433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinogalactan endo-1,4-beta-galactosidase"
                     /protein_id="HAQ4360061.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            complement(22117..23682)
                     /gene="guaA"
                     /locus_tag="IXR40_000183"
     CDS             complement(22117..23682)
                     /gene="guaA"
                     /locus_tag="IXR40_000183"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HAQ4360062.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVNARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(23741..24664)
                     /locus_tag="IXR40_000184"
     CDS             complement(23741..24664)
                     /locus_tag="IXR40_000184"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HAQ4360063.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            24860..25465
                     /locus_tag="IXR40_000185"
     CDS             24860..25465
                     /locus_tag="IXR40_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAQ4360064.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            25773..26789
                     /locus_tag="IXR40_000186"
     CDS             25773..26789
                     /locus_tag="IXR40_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAQ4360065.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            26930..28231
                     /locus_tag="IXR40_000187"
     CDS             26930..28231
                     /locus_tag="IXR40_000187"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HAQ4360066.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            28277..28939
                     /gene="deoC"
                     /locus_tag="IXR40_000188"
     CDS             28277..28939
                     /gene="deoC"
                     /locus_tag="IXR40_000188"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HAQ4360067.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            28960..29358
                     /locus_tag="IXR40_000189"
     CDS             28960..29358
                     /locus_tag="IXR40_000189"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HAQ4360068.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            29424..30506
                     /locus_tag="IXR40_000190"
     CDS             29424..30506
                     /locus_tag="IXR40_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HAQ4360069.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            30718..32280
                     /locus_tag="IXR40_000191"
     CDS             30718..32280
                     /locus_tag="IXR40_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4360070.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            32273..33406
                     /locus_tag="IXR40_000192"
     CDS             32273..33406
                     /locus_tag="IXR40_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4360071.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            33406..34362
                     /locus_tag="IXR40_000193"
     CDS             33406..34362
                     /locus_tag="IXR40_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4360072.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            34461..35627
                     /gene="deoB"
                     /locus_tag="IXR40_000194"
     CDS             34461..35627
                     /gene="deoB"
                     /locus_tag="IXR40_000194"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HAQ4360073.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            35651..36469
                     /locus_tag="IXR40_000195"
     CDS             35651..36469
                     /locus_tag="IXR40_000195"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HAQ4360074.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            36486..37193
                     /gene="deoD"
                     /locus_tag="IXR40_000196"
     CDS             36486..37193
                     /gene="deoD"
                     /locus_tag="IXR40_000196"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HAQ4360075.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(37491..38177)
                     /gene="gpmA"
                     /locus_tag="IXR40_000197"
     CDS             complement(37491..38177)
                     /gene="gpmA"
                     /locus_tag="IXR40_000197"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HAQ4360076.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(38349..38930)
                     /locus_tag="IXR40_000198"
     CDS             complement(38349..38930)
                     /locus_tag="IXR40_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAQ4360077.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(39063..39746)
                     /gene="rpiA"
                     /locus_tag="IXR40_000199"
     CDS             complement(39063..39746)
                     /gene="rpiA"
                     /locus_tag="IXR40_000199"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HAQ4360078.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            40065..40478
                     /gene="rpsL"
                     /locus_tag="IXR40_000200"
     CDS             40065..40478
                     /gene="rpsL"
                     /locus_tag="IXR40_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007085295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HAQ4360079.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            40562..41032
                     /gene="rpsG"
                     /locus_tag="IXR40_000201"
     CDS             40562..41032
                     /gene="rpsG"
                     /locus_tag="IXR40_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HAQ4360080.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            41126..43213
                     /gene="fusA"
                     /locus_tag="IXR40_000202"
     CDS             41126..43213
                     /gene="fusA"
                     /locus_tag="IXR40_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HAQ4360081.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            43385..44572
                     /gene="tuf"
                     /locus_tag="IXR40_000203"
     CDS             43385..44572
                     /gene="tuf"
                     /locus_tag="IXR40_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HAQ4360082.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            44979..45281
                     /gene="rpsJ"
                     /locus_tag="IXR40_000204"
     CDS             44979..45281
                     /gene="rpsJ"
                     /locus_tag="IXR40_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009488059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HAQ4360083.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL"
     gene            45312..45941
                     /gene="rplC"
                     /locus_tag="IXR40_000205"
     CDS             45312..45941
                     /gene="rplC"
                     /locus_tag="IXR40_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HAQ4360084.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            45969..46592
                     /gene="rplD"
                     /locus_tag="IXR40_000206"
     CDS             45969..46592
                     /gene="rplD"
                     /locus_tag="IXR40_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HAQ4360085.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            46592..46882
                     /gene="rplW"
                     /locus_tag="IXR40_000207"
     CDS             46592..46882
                     /gene="rplW"
                     /locus_tag="IXR40_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HAQ4360086.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            46921..47754
                     /gene="rplB"
                     /locus_tag="IXR40_000208"
     CDS             46921..47754
                     /gene="rplB"
                     /locus_tag="IXR40_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010747214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HAQ4360087.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            47797..48075
                     /gene="rpsS"
                     /locus_tag="IXR40_000209"
     CDS             47797..48075
                     /gene="rpsS"
                     /locus_tag="IXR40_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HAQ4360088.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            48098..48445
                     /gene="rplV"
                     /locus_tag="IXR40_000210"
     CDS             48098..48445
                     /gene="rplV"
                     /locus_tag="IXR40_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HAQ4360089.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            48459..49115
                     /gene="rpsC"
                     /locus_tag="IXR40_000211"
     CDS             48459..49115
                     /gene="rpsC"
                     /locus_tag="IXR40_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HAQ4360090.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            49118..49552
                     /gene="rplP"
                     /locus_tag="IXR40_000212"
     CDS             49118..49552
                     /gene="rplP"
                     /locus_tag="IXR40_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HAQ4360091.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            49542..49730
                     /gene="rpmC"
                     /locus_tag="IXR40_000213"
     CDS             49542..49730
                     /gene="rpmC"
                     /locus_tag="IXR40_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HAQ4360092.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            49755..50021
                     /gene="rpsQ"
                     /locus_tag="IXR40_000214"
     CDS             49755..50021
                     /gene="rpsQ"
                     /locus_tag="IXR40_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HAQ4360093.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            50079..50447
                     /gene="rplN"
                     /locus_tag="IXR40_000215"
     CDS             50079..50447
                     /gene="rplN"
                     /locus_tag="IXR40_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002460061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HAQ4360094.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            50484..50792
                     /gene="rplX"
                     /locus_tag="IXR40_000216"
     CDS             50484..50792
                     /gene="rplX"
                     /locus_tag="IXR40_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HAQ4360095.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            50820..51359
                     /gene="rplE"
                     /locus_tag="IXR40_000217"
     CDS             50820..51359
                     /gene="rplE"
                     /locus_tag="IXR40_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HAQ4360096.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            51378..51563
                     /locus_tag="IXR40_000218"
     CDS             51378..51563
                     /locus_tag="IXR40_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HAQ4360097.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            51599..51997
                     /gene="rpsH"
                     /locus_tag="IXR40_000219"
     CDS             51599..51997
                     /gene="rpsH"
                     /locus_tag="IXR40_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HAQ4360098.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            52029..52565
                     /gene="rplF"
                     /locus_tag="IXR40_000220"
     CDS             52029..52565
                     /gene="rplF"
                     /locus_tag="IXR40_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HAQ4360099.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            52726..53082
                     /gene="rplR"
                     /locus_tag="IXR40_000221"
     CDS             52726..53082
                     /gene="rplR"
                     /locus_tag="IXR40_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014125626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HAQ4360100.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            53103..53603
                     /gene="rpsE"
                     /locus_tag="IXR40_000222"
     CDS             53103..53603
                     /gene="rpsE"
                     /locus_tag="IXR40_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HAQ4360101.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            53618..53797
                     /gene="rpmD"
                     /locus_tag="IXR40_000223"
     CDS             53618..53797
                     /gene="rpmD"
                     /locus_tag="IXR40_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HAQ4360102.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            53841..54281
                     /gene="rplO"
                     /locus_tag="IXR40_000224"
     CDS             53841..54281
                     /gene="rplO"
                     /locus_tag="IXR40_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HAQ4360103.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            54281..55576
                     /gene="secY"
                     /locus_tag="IXR40_000225"
     CDS             54281..55576
                     /gene="secY"
                     /locus_tag="IXR40_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HAQ4360104.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            55638..56285
                     /locus_tag="IXR40_000226"
     CDS             55638..56285
                     /locus_tag="IXR40_000226"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HAQ4360105.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            56476..56694
                     /gene="infA"
                     /locus_tag="IXR40_000227"
     CDS             56476..56694
                     /gene="infA"
                     /locus_tag="IXR40_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HAQ4360106.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            56727..56843
                     /gene="rpmJ"
                     /locus_tag="IXR40_000228"
     CDS             56727..56843
                     /gene="rpmJ"
                     /locus_tag="IXR40_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HAQ4360107.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            56861..57226
                     /gene="rpsM"
                     /locus_tag="IXR40_000229"
     CDS             56861..57226
                     /gene="rpsM"
                     /locus_tag="IXR40_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HAQ4360108.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            57254..57643
                     /gene="rpsK"
                     /locus_tag="IXR40_000230"
     CDS             57254..57643
                     /gene="rpsK"
                     /locus_tag="IXR40_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HAQ4360109.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            57723..58661
                     /locus_tag="IXR40_000231"
     CDS             57723..58661
                     /locus_tag="IXR40_000231"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HAQ4360110.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            58689..59069
                     /gene="rplQ"
                     /locus_tag="IXR40_000232"
     CDS             58689..59069
                     /gene="rplQ"
                     /locus_tag="IXR40_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HAQ4360111.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            59341..60180
                     /locus_tag="IXR40_000233"
     CDS             59341..60180
                     /locus_tag="IXR40_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HAQ4360112.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMVFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            60156..61025
                     /locus_tag="IXR40_000234"
     CDS             60156..61025
                     /locus_tag="IXR40_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HAQ4360113.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            61015..61812
                     /locus_tag="IXR40_000235"
     CDS             61015..61812
                     /locus_tag="IXR40_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HAQ4360114.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            62015..62761
                     /gene="truA"
                     /locus_tag="IXR40_000236"
     CDS             62015..62761
                     /gene="truA"
                     /locus_tag="IXR40_000236"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HAQ4360115.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKVRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            63426..63663
                     /locus_tag="IXR40_000237"
                     /pseudo
     CDS             63426..63663
                     /locus_tag="IXR40_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299509.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(63807..64583)
                     /locus_tag="IXR40_000238"
     CDS             complement(63807..64583)
                     /locus_tag="IXR40_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAQ4360116.1"
                     /translation="MNIHHIRNATAILDYGGKKFLIDPMLAEKGTLPPFISKGPFPSP
                     RKDQMNPLVDLPMPVEDIINGIDAVIVTHLHLDHWDDIAKEVLPKEIKLFVQDENDAN
                     EIRLYGFKNVEVLREDTVFESIQLVKTKGKHGRGEILNYVGNVCGIVFKHSTEKTLYF
                     TGDTVWYEAVKQTIDQYNPEIIVANAGDNHFLVGESLIMGKDDLYELHKAIPDSTIIA
                     VHMEAVNHWGLSREELKSFNKEKGISEKVLVPEDGDNIFI"
     gene            64706..65113
                     /locus_tag="IXR40_000239"
     CDS             64706..65113
                     /locus_tag="IXR40_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HAQ4360117.1"
                     /translation="MLDQTDINIIEELSKNSRITMKELGEKVHLTGPAVSARVTKLEE
                     SGVIENYTVKLNMEKLGFSIHAFLIIITQNLNHKPYLSFIKNHEKFLIRNYKISGGGC
                     YLLECRFTSKKSMNSFLEQLNEYANYKLSIVID"
BASE COUNT        20824 a        11647 c        13798 g        19189 t
ORIGIN      
        1 ttatttcttg aagctgacca cttctgtcac aacctcttat tttgattaga acttgcgaaa
       61 ataaaccggt taaagtgtgt ctagcgcaag agatttgcta taatagacga taagggtaaa
      121 atgtaacgag aaggggttga aaaatgtgta tcaaattgta acagattctt gttgtgatct
      181 gccataccat gtattagcaa aagaaaaagt tgatttttta tcaatgaatc tccaattgaa
      241 tgatcaagag ttagtagatg acctcggaaa gacattcaat tatgaccgct acatgaatca
      301 gctgaaaaat ggtgcgatgc ctacgacatc acaaatcaat gttggccgat atttagaatt
      361 tttccgttct tatgcggaaa aacagattcc tgttttatat gtggcttttt ccagtggatt
      421 aagcggctct tacagtagtg cgcttcaagc ggttgaattg ctgaaggaag aatatgaaga
      481 ccctgagatc tatgtttttg atacaaaagc tgcaagtatt ggggaagggc ttttagtatt
      541 ggaagctgta agattgaaaa aagaaggtaa aagcatcgaa gaaaccctag agtggctgga
      601 aagtaattat ttgaaagtcc attcatgggt aacagtagac gatctgaaat atctagaacg
      661 aggcggtagg atttccaaag caagtgctac tcttggcagt ctattgagtg taaagcctat
      721 tattacggtg gataaagaag gaaggctgac gaatgttgac aaagttcgag gaagaaacaa
      781 gtcgatccag acaatcgtca atgagacggt aaaaacaatc gttgcaccac ttgatcaaat
      841 cgtttatgtg gcttacgctg gggatctaga gagcgcggag aaggcaaaac ggcttttgga
      901 agagcagata aagatgaaag atgtgaagct ttatccctta ggaccaacga tcgccagtca
      961 cacaggctat ggctgtatcg cgattttttc gatgggaatc agtcgataaa agcagtaact
     1021 cattctgtaa aaaagcccag aaattgattg taacaaaaac agcgactctt aaaagataga
     1081 tgagcatcct atctcttaga ggtcgctgtt tttttatttt ttaagctaaa taggccatta
     1141 tgcccataac tcgttcaatt gtttttgaat atctgcattt tccaaaaatt catcatatgt
     1201 cgtatcagct cgatcgatca cacctttatc cgaaacggca atgatgcggt ttgccaatgt
     1261 ttggataaat tgatggtcat gtgacgcaaa taagattgag ccagtaaatg ccatcaagcc
     1321 gtcattcaat gctgtgattg attctaagtc taaatggttc gttggatcat ctaatacaag
     1381 tacgttagct ttcgaaagca tcatttttga aagcatgcaa cggactttct ctccaccaga
     1441 taaaacattc actggtttca atacttcttc accagaaaac aacattcttc ctaagaagct
     1501 tcttaagaag gtgttatcat cttcttcttt acttgcatat tgacgcaacc agtctaaaat
     1561 cgttagatca gtatcgaatt ctttcgttgt atcctttggt aaataagaat tacttgttgt
     1621 cacaccccaa cgtactgttc cagtatctgg cgtaatttca cccatgataa ctttgaatag
     1681 cgttgttgtt gttatatcat tttctgcgac gaaagcgacc ttgtcttctt tgctcaaatt
     1741 aaaagatata tcatctaaaa ttttctttcc atcaatcgtt acacttacat tttctacctg
     1801 caataagtcg tttccaatct cacgttcagg tttgaatcca acgaatggat aacgtctaga
     1861 agaaggttgg atatcgtcta aagtaatttt ttcaagcatt tttttacgtg aagttgcttg
     1921 ttttgatttt gatgcattcg cactaaagcg ggcaataaat tcttggagtt ctttgatttg
     1981 ttcttctttt ttggcatttg cgtttgcttg aagtttagcc gctagttgac tagattccaa
     2041 ccaaaaatca taatttccta cataaagttt gattttacca aaatctagat ccgccatatg
     2101 tgtacatact ttgttcaaaa agtgacggtc atgggataca acgatcacag tattttcaaa
     2161 attgatcaaa aattcttcca gccaattgat cgattggata tccagaccgt ttgttggttc
     2221 gtctagcaaa agaacatcag gtttaccaaa tagtgtttgt gctaataaca cttttacctt
     2281 ttgtccacca gttaattcac tcatttgctg atggtgcaat tcttcaggga tgttcagacc
     2341 ttgcagtaaa acagctgctt ctggttcagc ttcccatcca ttaagctcag caaattctcc
     2401 ttctaattca gctgctcgaa taccatcttc gtcagtgaaa tcctctttca tgtaaatcgc
     2461 atctttttct ttcagcactt catacagacg cttgtgtccc atgatgactg tttcaagtac
     2521 agtatagtct tcatagtcgt aatggttctg tttcaatacg gccatccgtt catctggtcc
     2581 catagtaacg gaacctgtgg aaggctgcag atcccctgat aacactttaa ggaacgttga
     2641 tttacctgca ccatttgcac caatcaagcc atagcagttt ccgggggtaa atttaatatt
     2701 cacatcatca aatagtttgc ggtctgaaaa gtgcaaactc acatcattta cagtaatcaa
     2761 tttttttcct cacttttatc attattagtt ttgacaagtc ttatagaatt atatagggga
     2821 aaggtaaaag attcaaggca atcgaacatt ctttgtgttt cacgtgaaac agaatgaaaa
     2881 aaataaaaat aaaagcggag cgaaaatagc tactatagga tttattagtt tgcaacagca
     2941 taatttttga cgttatttat aagagggagt actataaaac tgtaaaagaa atgaaagaag
     3001 gattgaaaat ggatgaaaaa agaaccatcg actggggctc attgattttg ggaattttat
     3061 ttgtacttgt ctcattgtta tcatttcaag accctgtcgg aaatttagtt gcaattgtag
     3121 tagtctttgc gatttttgcc tttattaaag ggatatttga actgtttgta cggaacagat
     3181 taaaagagct aacaggatat aaaggaaaga tgcccttaat aatcgggatc atcgatattc
     3241 tagttggcgt ctttttctta ttcaatattg gtgcaggagt cgcagcattg ccttttgttt
     3301 ttgcagtatg gtttattgct gattcagttt tagcgttatt tactgctgac ttggcaagag
     3361 gagtaagtga aggatattat tggtttacga tcatcgtcaa tattttagga attttattag
     3421 gaattttctt attgtttaat ccaatttctt ctgcgttgac attaagcttt ttagttggat
     3481 tctattttat gttatttggt atcacacata tcgtctatgc atttagataa gtaaaatcaa
     3541 acaaataaaa aagccggctt ccgattacag ttttactgtt gtaattggaa gccggctttt
     3601 ttatcatgga caaatatgca cgaggtgatt tttaggtgtc gagacaaatt tatgcaaaaa
     3661 tgtgagaagc tatatacaca aattttatct taatactcga agcatagcgc agttgtcaca
     3721 acctcttttc atataattca ttcaatactg gcaaatcatg gacttcatat ttttctttga
     3781 atgcttggat ttcttcttca gaatattttc ttggatctaa atgcagatct tctactggca
     3841 atgggcgctt gttattgatc ttcacatcga ttactacagg acgatctgat tttgcagctg
     3901 catcaaaggc aaatcgaagt tgcgagtatt ctgtgactgt aaagctattt gccccgagcg
     3961 cttctccaac tttaccgaaa tctgcatctt ctaaaaatac accaaatttc ttttgttccg
     4021 tatcttcttg ttctgcttcg atgaaaccaa aagaatcatt cgaaaagaca acattaataa
     4081 ttggaagctg atatttgact tgtgtaatga tatcttgcat gaccatagca aacccgccat
     4141 caccacttaa ggtaaatact tgtttttctg ggtagcttag ttgtgcggca attcctcctg
     4201 gcacaccatt acccatagtt gcgaaccatc cagatgtcgt atgtttttgt ttaccgttca
     4261 tattcaataa acgaatagaa tggatagtcg tgttaccgac atctgtgacg aaaatcgcat
     4321 cgtcttcagc aatacgattg atttctttat agacagcctc tggacgaatc ggttcttcct
     4381 ctcgatcttc aaaagatttc aaccaattta cccatttttc tttattttct tgatttgcta
     4441 ggtaccagct atcagcaggg cgagcatccc ctaactcgac aagtctttgc aaagctgtgt
     4501 ttgcatcacc gaggatcgac aaagatgttt catggcgtcg tccaaatttt gacgcatcga
     4561 tatcgatttg gataaattca gcagttggat taaaaaatgc acgtccaaat gggaagtcgc
     4621 taccgacaaa taagatcaga tcggcttctg ccaatgcttc atttccgggt ttagtagcga
     4681 cacgtccagc aaaaccaaga aagttttcat aatcatcagg aataattcct tttgctagaa
     4741 cggaagcgac aacaggaact gaaaaatgtt ctgagaattc tttgatttgc ggaaatccgt
     4801 ttcgcgttcc ttgaccaaca taaagaactg gtttttttgc tttttcaaga taaggcaaag
     4861 cagctagcaa atctttttct tctggtaata tcacacttgt tttgtgagtg tgagcggtgg
     4921 agaaaggttg ttcgtcaatt tcttcaaaac caagatcaac agggatagtc acgatagcca
     4981 cgcctttatg ctcataggcg gctttaatgg cttcatctac tacatgcgga agactttgtg
     5041 gtgtcatgac tgtacgattg tatacgctaa catctgcgaa aataggattt tcatttagtt
     5101 cctggaaaga gttatagttc atggatgtag aagcaacttg tcctaagaac gctactagag
     5161 gcacatggtc catctgtgca tcatacaaac cattgatcaa atgtgtcgca ccaggtcctg
     5221 cagagccgaa gacagcgccg actttccccg ttaattttgc atctgcagcg gctgcgagtg
     5281 cgccgacttc ttcatgacga acttgaatgt agttgatttc ggttttttct tgatatagcg
     5341 catccataat tgaattgaaa gatcctccgg gaatgccgta aatatggtcg ataccccagc
     5401 tttcaagaac ttttaccatt gcgattcctg cattgatttt tgacatggtg tttcactcct
     5461 ttagcaatga tgatacataa attttttgta tctagagtat agaacttttt atcgaaaatc
     5521 ccaactaatt cgtcttttca caaaaatgta gtcatgtttt tgggaatatg ctagagtagt
     5581 acatagatag attcaagaga ggggaatggc atggttgaat ggctattgag acttgaacct
     5641 tggcagcaag cacttgctgg gacagctttt acttatttta tgacagctct tggtgccggg
     5701 ttggtttttt tctttaaaga aatcaaaaaa gaagtgctaa acttgatgtt aggatttgct
     5761 tctggtgtca tgattgctgc aagtttttgg tctttgttag atccggctat tacaaaagca
     5821 gaagaaaatg gagatattgc ttggctagtt gtaagtattg ggtttggttt aggcggtgtg
     5881 tttttatata tggcagataa aacactgccc catatgcatt ttggaccaca acatgaagca
     5941 gaaggattgc ctacccattt aaaacggacg atcttgcttg ttttttctat tacattgcat
     6001 aacattcctg aaggtttagc cgtgggggta gcattcggtg cagcagcaac tgcggataat
     6061 ccgacagccg ctatattagc cgctgtttcg gtggcgctag gtattggtat ccaaaacttc
     6121 ccagaaggag cagctgtatc aatcccgttg cgacaagaag gtctgagtcg taaaaaggcc
     6181 tttgtttacg gacaagcttc tggaatcgtt gaaccaattg ctggagtgat tggagcgcta
     6241 ctagtaacga aagtggagct gctgcttcct tatgcacttg cttttgccgc aggagcaatg
     6301 atttatgtcg tggtggaaga attgatccct gaagcacagc agacattgtc cagcaaacat
     6361 cattttgcag tttttggcgt catgagtgga tttatcatta tgatgatttt ggatgtggca
     6421 ttaggataaa taaaaaaaat atatatgata tatcaaatag ggccgcgaac ttatatcgcg
     6481 accctatttt tttagtaagt tatatcataa tgaagtgaat ggtatcatac attaataata
     6541 gttttttcta tgtgtatttc ctttgatcca gcgaacaagc cagatgataa gtgcgattgg
     6601 gattagaact ttgaccgcaa accataaaag cccgcttagg acactgacaa aaagactgat
     6661 gacgaagcta gctgcaatta gcactaaaag aaccatgaag atatttaaga acatattttt
     6721 ttgacgcata caaaaccctc ctcttgttca ttctttacta tagaaaaagt ataacaggga
     6781 ttgtttaaaa acacctccaa ctgaagactg atttttactt catctactta aatgatcaaa
     6841 caattgcttt ttctctggtt tatcatctaa aatagagcgg aaaaggagga gaatatcatg
     6901 cctaaaaatc gtcttgaagc atttacagat gctgtaatcg cgattatcat gactatttta
     6961 gttttagaac ttcatgaacc taacggagac acgtgggagg cgctcgctgc attaggttac
     7021 cgatttttta tctatattgt cagttttatc attttagcga tttattggaa caatcatcat
     7081 catttatttc aagttgtaca taagataaat ggacgggtct tatgggcgaa cagtttcttt
     7141 gtttttgcgc tttcgctttt tccgtttgca acttcatgga tcagtgagta catcaatagc
     7201 ctggctccag aaatgactta tggttttgtt accttgaccg ctaatattgc gtattatatc
     7261 ttggcaaaag aacttgtcaa agcaaataaa ggccacgaga aagcattgaa ggcgatgttg
     7321 aataattaca agaaatcgta tctatcgatt ggtttgaatg tgttaggaat tgtcttaggg
     7381 tatttagtag cgccagtagc cgtgctgatc gcaaacatcg tgattctagc tgcttggatc
     7441 atcccaagtc gtaccatcga atcacaatat cggtaaaatg atccgtgttt aaaatttaag
     7501 agaaaaatat agaaaaaata aataaacgat caaatatccg agtgatacta gtattcaaag
     7561 agggatgcag atggatcaaa aaagaattca tgtaggactg attactagtt ttgtcacgat
     7621 gcttatttat ttggatcaag gtcatttgac ttggacagta gttggtgtcg taggattttt
     7681 gacattattc acagcaataa aaaaataaac atctttatgt aatctgatgt tctatctatt
     7741 taagaaaagc atgtttacag cagtatgatt ctgttgtaaa cgtgttttta tttgtggaaa
     7801 atttaatttt tagaaaagtg tatcgaaaaa tagatagtta gtttttccac agtggataac
     7861 ttcgtaagag ataaaaataa aaaattagtc aaagaagggc gtatagattt cttttgatag
     7921 gagatataca acagaaatga ataaatatta acgtgttttc aaacagtata aaacggtgtg
     7981 gtttttggaa taaaaaaata acatatctca ttttacactt ttgttatttt atacttaaaa
     8041 aataacgaca cagaaaatac cgtgtctcag atttctctac tacttctaaa aactactgtt
     8101 tttttccttt gaaatgcctt caaaaagtag gatcaggcag aatatactgg cagaatcaag
     8161 gagaagggag cctaaataag gagaaaaacc atagaaaata taaagtaatt acttataaaa
     8221 caagcttttt atagaaaaat aatatacctg agtagggtat aaattaagac ggaattcctt
     8281 tctagattga gatattgact aggaagaatg ttaagatttt aagcctttaa gctaaaaaaa
     8341 aacccttttt gttaaataag gggaatatag cctgtcagtt tcaaactgca agtcgtcctg
     8401 ctgcaataat atagtagatt agagatgaaa atagattttt ttaaaccaat gactgaataa
     8461 aaagaccgtc atagatacac attggaatgt gtctattacg gtcttttttt acgaacgatt
     8521 ttattgaaga cggacagttc gggtcaaaaa taaaaaagct acgatcagaa ataagaataa
     8581 aatgtatccc aaaataatgg ctagacggtc taacttattt gtcgatagat gtttgtttag
     8641 aagttgatag gcccataaac ctatcagtcc tcctgttgta ttagttatca aatcagtgat
     8701 gtccgctacg ccaataccga ataggaattg aatcaattct gccaagaagc ttacaaggaa
     8761 aataatccct aattttttag aaaaagaaag tctcttgaaa ttgacattca aaagcacccc
     8821 aaaaggaaaa aagacaatca agttataagt ggtctcacgt aataccgtcg tattttcaaa
     8881 agaaaaagta gaaaaaggga cgagattgac attgctgtaa gaataagtga gaaattgtgg
     8941 aagattaaat gatagcttga ataaaatcaa ccataataga aagaataaat aaatccctaa
     9001 taaaaatttt gatacatacc gcatagacat ctcctccatt taaaaagtat accatcgaaa
     9061 accgctgaaa aatcataaaa aagtatgaag tttaaggacc aacgtagtta tcgtacgaaa
     9121 attagaagct tttttttgtt gggaatccgg tttctttaac aaagctaaga tagcgagttg
     9181 cttggaaaag ttgctatctt ttttctgtca aaacgactcg gaatgttcgt tttttgttct
     9241 aatttctcca agttgtttac tttttgatac taagtttatg aaaaatcaag aaatagttgt
     9301 tatactaggt aatgctgaca aacgggattg gcatttcatc ttggttcagc tttttttcca
     9361 attactagga aggagggata gattgttcaa gacttatttt cgtttcaata aaatacaaga
     9421 taatcctttt cgtatcatga atctgatgct acttatcttt attgtattat ggttaggtta
     9481 cataaatcat gattttttga tttcaagttt ttcatcatta gggatcttta cttttttcta
     9541 ttatcaaaac ataccgatga aatatttgct gaaacgtatg tttctgatcg gttgcggact
     9601 gttggttgct ttcgttttgg ggatcttatc gacttatgtt ttatggcttg aaccatttgc
     9661 cgtagctttg gttgcttttt ccagcagatt cgtgttgcga ttattccata tttctaaacc
     9721 aggtggcttg ttttttgcga tgctttctgc catgggaacg agcatgcagc tgccaatcgc
     9781 tcaattaccg atcgtctcac tttatttttt tatgggtgtc gtttttgccc tgattgcggc
     9841 agtgattaca aaattactgg attcacggcc tgagcagaca attgaaaaag caactttaaa
     9901 agaaagattt cacgaagagc ctttagtgat cattgattct gttttctaca gcgctgcctt
     9961 atttctttcc gtttatgtca gtcacggctt gaatctgcat aatccttatt ggttgacctt
    10021 gtcatgtgca tcgattttgc tagcagaaaa cttggatgcg atgaagcatc gacaagtcca
    10081 atatctgatt ggatcgatgg gtgggttatg tgtgtcggca ttcttgtcat ttgtgccgtt
    10141 tacgcagttg cagaccattt ttctgatcac ttttctatat ggaatcgcac aatttctagt
    10201 tgctagaaat tatgcagttg ctaatatttt tcttaatccg atggcgttga tgctatctac
    10261 acttattcgt ggagcatact tgatttcttt gatcgaatat cgttttttag ggatcgtcat
    10321 aggaagtttc atcggtttag gtgttgcgtg ggtaatgacg gttggtttgc aacattattt
    10381 aacggttgtt cgtcaaaaat tagaatagaa ggacaaatat atgtgccaaa agaggttatg
    10441 acaagatttt tgtcacaacc tctaattcaa ggtgttcaaa agccagattc tcagcattaa
    10501 gtcaaattca cacaaaaatg tggaaaggaa ctttcaaaaa aattttatat ttattctatc
    10561 aaaaaatttt gtttatgatg gtaactgaat aaactttcct gagatggtca atgctttcct
    10621 tgaaagtctt acagatattc tttcttcata gaaagtttaa gttttatagt tagtgtacaa
    10681 taaaagtatg tttataccat atggtgtccg gataatcagt catttaaaca atgaggttca
    10741 aagatatgaa aaggggaaat ttgatgaaga aaataagcaa tgaaatccaa attctggcag
    10801 aaactttaac tcttcccaaa gtcgttatag agcaaatgat tgtacaagca aaaaacatcc
    10861 ttgatgaggt gtttgagcaa tatagtcatg aactaatgga tcctaataaa gcaaaggcga
    10921 ctgcaaagaa aatagacaaa gtctatgaag aggaaccttt tgcagcatta gctatttatc
    10981 tatatgcagc ttctcaaagt tggaaaaaaa tttatcaacc attgaagatt ccaagaacta
    11041 tctatttggc aacaatgaat gcttttacta gatttattca tgaacatttc caagtaacag
    11101 gaagctatcg ctttgaccgt ggtttttgga tttggcatta cactagtggc ttgatctttc
    11161 ggattggtga attggagtac gaaatgacat attttccgaa agggtacacg gatctaagat
    11221 tagaaggaaa gcagtgcctt tctcttcata ttccttccga tgcagattta tctcagaata
    11281 agataagaga tagttacgaa agtgccattc gtttttttga actttatttt cctgattacc
    11341 attaccaagt gatgtacaca gatacttggt tactatcacc caatcttact aaatggttga
    11401 aaaaagagtc aaaaatctgt ctttttgcag ccgattatcg attattatca gttgatgaac
    11461 aggacgatag tggagtccct tggatctttg gacgagtaga tgcccaaata catgattatc
    11521 cagaaagtac gagtttacag cgacaagcaa aagagcaatt gcttgcaggc gagcacattg
    11581 gctctggctt aggtattctt acttcataag tttagtactt cgaaatagtt taaaagagcg
    11641 tgagacaaaa gtaaagaaca cttttgtctc acgctctaaa cacgtataaa cggcggaagc
    11701 agaagcaact ccttcggaaa taagctgaaa ttcacaaaaa tttgaaaagc aattttcgtg
    11761 aatttcttct tatttcttgg agttaaacgc ttctgtccca gcctcttttt tagtgttcta
    11821 tcgaacacac agtacgttca ataggtaaac tagctataac aatagatatt aaagttaacg
    11881 gacaagaggg ccttttttag gtagctaaaa cgtaataatg aaaatttatt tccagagata
    11941 ggagtcaatc agctagtctg atcgactgtt ttaacaagtt gactttcatt ttaacttttg
    12001 ataccattta aaacacaaat cgtaattgtt tcgatttgtg ttttttagca tgactacaat
    12061 caaagaagaa agtgggtcgt ccatatggaa aaaacagata tctcaagtgc ataccgccgc
    12121 ttgaaaagcc caaatatcaa aacacgaaaa cgtgcgctga agatcatcaa agatgtgaaa
    12181 cggaatagtg ggaaaaggta agaagaagga aacttaatta aaaaaatagc cgaaaaacgt
    12241 ttttcggcta ttttcaataa tcggtttttg tgtaaggttt ccgaaagaac tgctgttgat
    12301 tttccatttt taacatatga taaattggta gaatctttct tttcaaattg ataccattcc
    12361 ctaattccag ttatatagtt aactacagaa ccacaaagca cgtacgttta taaaagtatt
    12421 atctgtagtt atttttcaat tccctttcaa cctcttattt tgaccagtag tattgatcac
    12481 tttacctttt aacacctttg ttcgtttttg aaacattttt agtcaagaat ggaaacgtaa
    12541 ctacataatc aaaggttttg cgaaatattt catgaaatat ttcatgtaga agcgagcaat
    12601 acggttgcaa ataaccatta tcgtttaata agcagttacg aaagctccca atatctctaa
    12661 cgttcagctc actccatttc ttttcttcaa aaaaatcagt gattcgtatc tctttctatt
    12721 tgtcgaaaaa gttaacttta aaaagtaacg ccgaaaaaat atgcaaaaaa ataaaaaagc
    12781 agttactatt gctagaataa catcaaggaa taataagttt tggttttcag ataatagtcg
    12841 ataagttgtg tattggaatt ttagatacag taataaagta tttttcatga aattttgtga
    12901 gaatcactat tacaagtatc tttaataaaa ttaatggtta aggaggaact taaagtagaa
    12961 tgtaaatgaa tagttgtagt cagtcgattg tgatactaga ctcaaagttg caggaataag
    13021 tttttcaatt tgtgattgga agataaaaaa tgaaaaagaa gggctttttt ttatactttg
    13081 ttgattgtag tgtttatttt ccctctgttt agccaagtaa cattttctat gactcaacca
    13141 gtttcaagtg aggaacatga taaccttttt cgtgctacag aagagtttaa gaaatatcag
    13201 gaaaatattg ttccggagac tccattagct agtgagccaa ttactgatat tgatggaaac
    13261 caaataggat ggtatataca gtacgaagtt atggtggtaa ataatgactc aatagtaaaa
    13321 aatacagtag gcttagagct aacaccgatt gaaaaggtga gttcattgtt aacgtatatt
    13381 tatactgatg aaagtgacga gactgagatc attttaacgg attactcaaa aattgctact
    13441 gataaaaagt atatattgtg gatgtagaca ctagtgaaat actttatgat atagaaattg
    13501 atgaaaattt actagatgta gcacaagaaa tcgatcatca aaagcaggaa gctattcgat
    13561 atgctggtag aaaagggaaa agaaaatatt tattacgtga atgtagcaaa agttagagaa
    13621 gatgaaaatg agtggaaaga attcaagagt cgctactcaa ttaactcgac tccgacattt
    13681 acagtttaca gagaaggatc gatagaaaaa actgtttttt ggactaaaga aagtggaatg
    13741 tctttagctg aagtagaaga gtttttggat tatgttagta tgcaacagta agggagttct
    13801 tattatgaaa aattttgaca catattatgt tattgttttt tcgatatctt tgctgttaat
    13861 attactaact ttaatgcagt ataaagagta tccagagtat tttattttaa cttttgtata
    13921 tttagtaagt agctacacac ttctatataa attcagaagt tcttctagag tttctaaagt
    13981 ttgtttctta attagcttat tgattctata atatttttga tttatatagg aaattaaaaa
    14041 tattatagaa tcaacactca gagaacgggt tggtttttaa tagatttaat aagtactgat
    14101 aatgaaattt ctcctggttg ggaaaacgaa gttggttacc ctgtagaaga attttttcaa
    14161 gattactttg cggagtatgc cgataggata atgagagatt acgtaacaga taaaactcaa
    14221 gaagtcatca atcaatccca gtcattaaat gaattatctg ataaggcgaa agaagaagca
    14281 gttgccatta tttcttcagg gattagtgac tatattgata tgagtggtga aatcaattat
    14341 ggcgataaag acaaaattgt acgcatgata aaagctttta tcaaaacttt tgatgtgaag
    14401 gcagatctta agtttaatga tacttaccta gtaggaaaat taattaatat ccttgggaca
    14461 gagaaagata cggaaacgtt tatttcctct ttgtctatgt tgtttacaga taagcatttt
    14521 tcaactcagc ttggtggaga ggaactagtg gaaatctttt aaccattacg cccagcatta
    14581 ataaaagtat atcaaaaaag tactcctgat gatttttaag attggtttga gaaataatgt
    14641 gaaaacacta tttttaatgt taattataga tagagatgaa cgcgtcatat ggttaaaaga
    14701 atgaaaaagt caaagataca ctgctatatt tcactaagga tatagcagtg tatctttcat
    14761 gtcgtttcac tggcagtttt ttataaaagg aggtgtgcat ttcagttgct tttctttggt
    14821 agttagttga atcgtttaag aattaacgga tgtggcagac aggtgctctg tccaaaaacc
    14881 agtaaaatct ttgatggttc catctttatt tagctgtgcc tgttcaaata ctgttttgtt
    14941 tttaccgaat ggatcaattg caataattgt tccgatcccc gcacgtttgg cagcaagtaa
    15001 tcctgagtaa gcatcttcga taacaagaca atcagccgga gctaagctca gtttgtctgc
    15061 cgctttaaga aaaatatccg gttgcggttt cccagggaaa gagccgtcgt catagacaat
    15121 cttgtcccag tcaaaccagc gggctaaatc gaaaatatca aaataaaaag caacattctc
    15181 tttgacagta gccgtggcaa tcgttaatgg aatctgttgg tcagtcagct ggtcaagagt
    15241 cgcttcaagc ccttttgtca actgaagctc gttttcattt tgcaagcaaa gcatacgata
    15301 atagctttct ttttcttctg acaatacggc gatctcagag gcggtcaaat gctctgaaat
    15361 gaaatgtttc aaaatctccg tattcgtccg accatgaata ttttttaaaa tatcctcgtc
    15421 tgataaacca tcttttgtat gatcatgtat catatgcagc caagcagctt catgcagatg
    15481 agagtccaaa aacattgttc cgttgaaatc aaatataatc cctttcatag ttacgctcct
    15541 atagtggtat tttcggttga atcagcaatt tgcagatcga catattgtgc atagtgctct
    15601 tgaacctccc gcgagatctg gcgatccgta atgagcagat cgaaatcatg caaattataa
    15661 aacacataaa aatcatctcg attgaatttt ttattatcaa cgagtagata tttcttacgg
    15721 gaattattta gagcgatctg ctgtgcttct ccttcttcgg tactgtaagt agagatcgct
    15781 tcgttgtgaa cgccatttga actgataaat gcttttgtaa actttagtct tcttaaattg
    15841 tcgttggtga tcggtccgac aaatgcgccg gtatttttcc ggaaatcacc gccaatcagt
    15901 agaatttctg gtccatctgc ttgagcaaga atatcaaaaa ctggataatt atttgtaatg
    15961 atccgaattt tcttgttcag taaatgcgtc gccaatagtt cgattgttgt acctggtcct
    16021 aagaaaatcg tttctccctc gtgaatcaag gaggctgctg tggcagcaat ttcttttttt
    16081 tcttgaatct gcagagtggc tttttcagtg tgagaaagtt cttgatctaa agtgtaggaa
    16141 agactttgag cccctccatg gacacgcagc agcttgcccg atttttctaa ttcatctaaa
    16201 tctctgcgaa cggtcatatc agaaacatct aattgattga tgatttcatt aacggtaagg
    16261 attccttttt tattgaccat ttctacgata gtaagcaatc tttctttttt caacattgtc
    16321 ttcacctcta atttaaggat aatctatcat ataaacggac aacagtcaat ctaattcgaa
    16381 caaaagtaaa catttagggt ggtttttatg tttgttacaa tagattttat tgctgttttc
    16441 tggtttttat gattatttgt gtttgttttt gttgacaaat gttttggatg cgtttacaat
    16501 gcaatcagtt agaaagagcg aaaactgatt atagatttga ggagagatgt acatgcttaa
    16561 attaccagaa gattttattt ttggcggagc cacagcagcc tatcaggttg aaggagccac
    16621 taaggaaggt ggcaaaggcg ctgttgcttg ggatgacttt ttagaggaac aagggcgatt
    16681 cagtcccgat ccggcaagtg atttttatca tcaatatgca aaggacattg aattgtgtga
    16741 acgttttggt gtaaatggtc taagattatc cattgcttgg agccgcattt ttcctgatgg
    16801 agctgggaaa ccaaatccag aaggaatcgc tttttatcat cgtgtgttcg aagaatgtaa
    16861 gaaaagaaac gtaacgccgt ttgtgacgtt gcatcatttt gataccccta aacgtttgtt
    16921 tgaccatgga gattttttga atcgagaaac aatagaagca tttgtttcct atgccatttt
    16981 ttgttttcat gaattcaaag aagtcaaggt gtggagtacc tttaatgaaa tctatccagt
    17041 tgcaaccaat caatatttgt taggtgtttt cccaccagga atcaaatatg attttacaaa
    17101 gatcgtcgcc tgtcttcata atatgatggt tgctcatgcc cgtgtagtga actatttcaa
    17161 agaaaacgaa cttccgggtg aaattggtgt agttcactca ttagagacga aatatgcggc
    17221 aacagacgcg ccggaagata agcatgctgc ctttttagac gatgcattgt cgatccgttt
    17281 cttattagat gctacctatt taggctatta ttcaactgaa accttgactg ctcttgatga
    17341 gatatgtgaa gcaaatcagg ccagctatca ttttcctgaa gaagatttcg ttgaattgaa
    17401 aaaagcatcc acgcgtaatg actacttagg gatcaatcac taccaatgcc attttgtcaa
    17461 agcttacgat ggagaaaatg caatccatca taacggtacg ggtgaaaaag ggacctctgt
    17521 ttataaagtg aagggaatcg gagaacgtat ttataaagaa ggaattcctc gaactgattg
    17581 ggactggctg atttatccag aaggtctata tgacttgttg ctgcgaatta aaagcgatta
    17641 cccacattac aacaaaatct atatcactga gaacgggatg gggtataaag atcagtttga
    17701 agatggcatt attatggatc agccgagaat cgactatttg agagtctatt tggaatcctt
    17761 aagcaaggcg ataacagccg gggtaaatgt gaaggggtat tttttgtggt cgcttatgga
    17821 tcttttctca tggacaaatg ggtataacaa aaggtatggc ttgttttatg ttgattttga
    17881 aacccagaag cgttacccaa aagaatcagc ttactggtac aagttggtca gtgaaaccaa
    17941 aacgattatt taataagtga taatggagga agaaaagatg aataaagagg aattacaaat
    18001 gcttggtttt gagatcgttg catattcagg cgacgctcgc agtacattat tgaaattatt
    18061 gaaagaagta agacaaggaa actttgaaca tgttgattcg gcgttgaaag aagccgacga
    18121 aaatttaacc cttgcacata attcgcaaac aaaaatttta gcggaagaag catctgggaa
    18181 agagatggag atgggattca tttttatcca tgggcaggat catttaatga ccactttatt
    18241 gctgagagat ctgattcaag actttattgt actgtacaga cagaatcaag gataggagaa
    18301 gaacgctatg gatggaatca ttaaacaaat cgaaaaaggg aaaccatttt ttgaaaaaat
    18361 ctcacgtaat agttatttag gagccgttcg tgacggattt ttaacagcga tgccagctat
    18421 tttattttca agcattttca ttttgattgc tgcggttcct gagatttttg gttaccaatg
    18481 gcctgaatct gtctccacat ggctatggaa agtctataat tattcgatgg gtgttgtagg
    18541 gttactcgtt tcagcaacca ctgctcgctg cttggctgat tcgatgaatc gtcgcttacc
    18601 gaaaaacaaa gtaatcaaca ccacctctgt gatgctggcc tctgtggtaa gtttcctgtt
    18661 gttaagcgtc tctccgattg aaggtggatt ttcaacggaa tatatgggga caaagggact
    18721 actggcttcc tttgtcgctg catttttaac agttaattta tataagtttt gtgtgctgaa
    18781 agatattacc attaaaatgc ctaaagaagt tcctggaacg atttcgcaaa ccttccgaga
    18841 tatttttcct ttctcttttt cagtatttgc ggccgtttta attgatttag gcattcgaca
    18901 aatcttccaa atctcatttg cagaagcaat cattacggtg ctgcagccgc tatttacagc
    18961 agctgacggg tacttaggaa tcgctattat ctggggagcg atggcgctgt tttggtttgt
    19021 cggtgttcat ggaccgtcga tcgtggagcc ggcaattgcg gcaattatct atgccaatgt
    19081 ggaaaccaat ctgcaattgt tcaattccgg tgaacaagct tctaaagtac tgacggtggg
    19141 tttagggaat tttgtaggaa ctatgggagg aactggggca acattggttg ttccttttat
    19201 cttcctactc tttgctaagt ctaagcagtt gaaggcagtt gggaaagctt cctttattcc
    19261 agtaagtttc gctgtcaacg aaccattgct atttgcggca cccatgattt tgaaccctta
    19321 tttttttatt ccatttttgt taacacctgt tgtaaacgtt tgcctgttca agttttttgt
    19381 cgatgtattg ggcatgaaca gctttatgta cgttttgcct tgggcaactc cagcaccgat
    19441 cggtttggtt ctaggaacgg gcatgggtat cttagctttt gttctagcag cggttctaat
    19501 cgtcgttgac ttcctgatct atctaccatt ttgcaaagca tacgatgctg tcttagtaga
    19561 gaaagaagca caaaaagcag aggtgatcgc aaccgaggaa ggtgcttctg ccgatgtacg
    19621 tgaggaagta cctgtggcag cgagtcaagt tatcagcgat gcaaataaag aaatcaatgt
    19681 gttggtactt tgtgctggcg cagggacaag tgcgatgtta gctaatgctt taaaaaaagg
    19741 tgcatctgaa tcgaaagcac cgatcagtgc aatggcgggt gcttatggtt ctcattacga
    19801 aatgctgcag gattttgata tggtggtctt agcaccgcaa gtcaattctt actatgatga
    19861 tatcaaagaa gacaccgatc gcttaggaat caagctggtt gcgacaaaag gagcagaata
    19921 tatcggatta acgagagatc ctgaaaaagc tgttcagttt attctgaacc aatttcaata
    19981 aaggaggagc cataatgaaa atgggaattt ggttgcgtaa agctgtttta tttgcagctg
    20041 tgttaggggc tttgggggct gtttcaaaaa ctgttgaagc atctgccagc gaatttattc
    20101 gcggagcaga tatttcgatc ctgtcagata tggaaaaatc tggtgcaaaa tattatgaag
    20161 acgatatttc aaaagatgcc ttagagattt taaaaaataa tggtgtcaac tatgttcgac
    20221 tgcgtttgtg gcaggatcct tataatagta atggagaaag ttatggagca gggacaaatg
    20281 atctggaaac gacgattgac cttgcaaaac gagcaaaaaa tctgggactt aaggtgctgc
    20341 tggattttca ctacagtgat ttttgggttg atcctgggaa acagaatctt cctaaagcat
    20401 ggcaaggtct gacctttgaa gaaatgaata cggcattgta cgactataca aagaacgttc
    20461 tgtcggaaat gaagcagctg gacgtttatc ctgatatggt tcagatcggc aatgaactga
    20521 atagcggaat gctctggcct tatggcaagt cttggggaga aggcggggga gaatttgatc
    20581 gattggctgc ttttttgaag tctggtatcc aagctgttcg agacactcaa cctaaaacaa
    20641 ctccagtaat gctccactta gctgatggtg gcgatacagg agcatttact tggtggtttg
    20701 atgaaatcac gagtcgaggt gtgtcatttg atttaattgg agtgtcgtat tatccgtatt
    20761 ggcacggttc aatgaatgaa cttcaaacca atatgaatgc gatcagccaa cggtatggta
    20821 aagaagtgat cgtagttgaa acagcttatg ggcatacaac agcgaatgcc gatactatgc
    20881 caaatgcttt tggtgaagcc gaagcagctg cggggggata tgaaccaaca ccgacaggac
    20941 aagcagagta tttgctggat cttgccgatc ggattcaggc agtaccgaat aatcgcgggg
    21001 cgggcttctt ctattgggaa cctctttggt acaacggaaa tgtgagttgg gcaacacaag
    21061 caggtatgaa ttatctcagt gttcaatcca ctatgggaaa cgaatgggac aaccaagcga
    21121 tgtttgattt tgctggaaac gccttgccaa gcttgcgtgc gtttaaacaa gcaggggcgc
    21181 aaataaatct agttaaaaat gcaagtttcg aaagcgatgg accaacgacc agtccttcca
    21241 attggcaaac ctggtttcaa caaggaaccg ctaagggtac gatcaaaacg gaagcgggca
    21301 ctttttttgg ggactacaaa ctaacttttt ggcaggatca agcatacgag gcatcagctt
    21361 atcaaaatgt tagtggcata agcaaaggaa cttacacatt gagtgcctat gtaatgtctg
    21421 ggggagagtt tgatactaat cagttatata tcaaaaatta tggtggagcg gaactaaata
    21481 ctgcggttgt taaaacaagt gaatggacaa aaattacaat caaagacatt ccaattacaa
    21541 caggtgtttg tgaaattggg gtttatagca aggcttcagg aaatgcttgg acgaacgttg
    21601 attttgtttc attggtgaaa caatagactg cggatcgttt cgattcaaga tcggaggttc
    21661 ccttcagcca catcgttagc gtagaaggca ggaatcgaac ctgcacctcg cctttgccaa
    21721 aaataaccag aaacgatttc cagtcatttt taccaaaacg agtaaagcac cagacttcat
    21781 ctacactttg tattatgcta aagagagttc aacgatttcg taagaagcaa tgaaaaaatt
    21841 gcaaaaagtt gtgcagataa cataaagttt gtttaagaaa gggtaacctt agaattccgt
    21901 cgtgaatatg atttgagcac ttagatggat agaaaaaagt tctcggaaaa cagttcgttt
    21961 ttcgagaact tctttttatg ataagaatga aacaaattaa cttatattat agtctctttt
    22021 ggtagggaac catcttattt ttaatgaaaa tcaagcattt tagctattga agaatgttga
    22081 tttataggga ttccccctcc atattatgtt ggctctttat tcccactcca ctgttgctgg
    22141 tggtttagaa gtgatgtcat acacgatacg gttgacgtgg gctacttcgt ttacgatacg
    22201 tacagagatt ttttgcaaga cttcccatgg gatacgggca aagtcagcgg tcattccgtc
    22261 gattgaagtt acagcacgga taccgactgt gtagtcgtaa gtacgtccgt cacccataac
    22321 accgacagag cggatccctg gaagaacagt gaaatattgc cagatatcac ggtcaagtcc
    22381 agcagctgcg atttcttcac gcaagatagc atcagattcg cgtacgattt ctagcttgtc
    22441 ttcagtgatt tcgccaagaa cacgaatacc aagaccagga ccagggaatg gctgacgcca
    22501 aacgattgaa tcaggcatgc ctaactgagt ccctaattca cggacttcgt ctttgaataa
    22561 tgtgtttaat ggttcgatca attcaaattg catatcttct ggcagtccac ctacattatg
    22621 gtgagatttg atcgtctgtg ctgtttctgt accagattcg ataacgtcag tatacaacgt
    22681 tccttgtgct aggaaagaga cgccttcttc accagcaagt tttgttgctt cgtcatcaaa
    22741 aacatatacg aattcattcc caatgatttt acgtttttgt tctgggtcag atacaccttt
    22801 caacttgtct aagaagcgat ctcttgcatt gactttgatg atgttcaagc cgaattttcc
    22861 gcctagactt tccattactt gttccgcttc gcctttgcgt agcagaccgt ggtcaacaaa
    22921 gatagatgtc aattggtcac cgatcgcttt ttgtaaaaga accccaacga cactagaatc
    22981 aacgccacct gaaagaccaa gcaagacttt tttgtcacca acttgttcac ggattttttc
    23041 tacttgcata tcgataaagt tatccattgt ccagttacct tcacagtgac aaacatcaaa
    23101 ggcaaagtgg cgcagcaatt cgattccgta ttcggaatga cgtacttctg catggaattg
    23161 gataccataa aaattacgtg ttgtgtcttg gatagaagca atcggacaat ctttgcttgt
    23221 tccgactgtt tcaaagcctt caggaacttt agttaccaag tcaccatggc tcatccatac
    23281 tgtttgttgt tttggtgttt ctttaaacaa gacagcttga tcgcttgtta cttctaacaa
    23341 ggctttccca tattcgcggt ttttagcagg ctctacggaa ccgccaagtt tgtacgtgat
    23401 caattgcata ccatagcaaa tccctaatac aggaatacct aaattgaaga tctcaggatc
    23461 gatcccaaat gcattctcat catatacact gtttggtccg ccagaaagaa tgattccctt
    23521 tggattcatc gcttttactt cttctgcagt aatgcggtgg ctcaataatt cggaaaagac
    23581 tccaagatca cgaatacgtc ttgtgatcaa ttggttatac tgactaccgt agtctaatac
    23641 gataatcttt tcaacgttcg tcatatcggc aacgtttgtc aaatttatta cccctatccc
    23701 tttaaatttt atctcaaaat agtcaaacta ttttaaaatg ctaatatttt cgcatgaaaa
    23761 tcgaatcgat gatatgattt tcagttttat ggagaattat atcggctctt cctcgtgtag
    23821 gcaagatata ttcctgtaaa tttttcaaat tcacattttt ccatacatct tttgccattt
    23881 taaaggcttc ttcacgatct ccgatagcaa aacgataata ataattctct ggattttgga
    23941 aagccgtatc cagtaacgca ccaaaacgat ccaaatacca tttttcgatc agcacgggat
    24001 cggcatcgac atagacagaa aaatcaaaaa agtcgctgac gtagatttgc tgattcgcag
    24061 gtaattgaag cgtattgatc ccctcaacga tcaagatatc aggctgctgg atcaattcgt
    24121 acttgtctgg aatgatatca tacacatcat gtgagtaaac aggtactttt atctcttcct
    24181 gaccagattt tacacggttc aagaaatcga tcagcatctc catatcataa ctttcaggaa
    24241 atcctttacg gtccatgatt ccacgctctt ttaatatacg atttggataa agaaatccgt
    24301 cagtcgtgat cagctgaacg tttcttcgtt tgaaggtacg agacaaaatc gtctgcagca
    24361 gtctggctgt tgtacttttt ccaacggcta cacttccggc gatcccgata ataaaaggcg
    24421 gtacttctac gtatttatga agaaataaac ctttactcaa gaacaaagat tcaaattctt
    24481 tcatataaag ataaatcaga tgagcaagag gtacatagat atctcgaaca tcctgcatgg
    24541 aaatgcggtc attcaaactt ttgatattat ctagttcatc ttgtgtcaaa ggtgcttgcc
    24601 cattacgata aaattctcgc cattcttctc ttgccacacg gtagtagttc attggatcat
    24661 tcatattagc ctcctgcgtt ctcccatcaa tggaactatt ttaacacaaa ataaacgcaa
    24721 accccaccac ttaagagaga ttgccgatct ttttgtataa tctttataat agaaagaaac
    24781 ggagtcttat tcttgacttg cgcacggata cataaaagga tagactgttg tcatgaaaga
    24841 aatgagaagg atggaagaca tgacaaatca ttactattct gaacgcccag atacggcgca
    24901 cgattttgaa caatgggctt ttgagttaaa aggcagaacc tttcaatttg taacagattc
    24961 tggtgtattt tcacgtgaaa cagtggatta tggttcacgt gtcctgattg atgctttcga
    25021 ttgggaagag ttacctgatg aaggaaagat cttagatgtg ggatgcgggt atggaccgat
    25081 tgggttagct ttggcatttg cgacacagcg gtttgttgaa atggtcgaca ttaatgaacg
    25141 agcggtaagt ctagcgcaag gaaacgcaaa gcgtaaccaa atcgaacatg ttgatatcca
    25201 tcaatcgaat atctatgaag cagttcatga agaaacctat gcagctatcg taagcaatcc
    25261 gccgatccgt gctggaaaaa aagttgtaca tgaaattttg acaggcgcat atcctcggtt
    25321 gaagaagggc ggtacactga caattgtgat ccagaagaaa caaggagcgc cgagtgcgca
    25381 aaagaaaatg gaagaaacat ttggtaatgc agaaatcgtc acaaaagata aaggatatta
    25441 tatcatcaaa agtgtgaaag aataactagc tgaaaaatag tggagcgacg aaagagtgga
    25501 actgggcgtg catgtacggg tacgtatcag ttcttttttt gttgagaagt ttttaaaaac
    25561 aaagaactat tttttcttca aaaagaaata gtaggaacag agtcgttgtt ttttacgata
    25621 aaataaataa gatacagaac ttgtatagaa ggctgccaag tcggtagata aaggaggttt
    25681 ttatcaaaaa acatactttc cttttttctc tattcttttc ttgggggttt tggtacactg
    25741 atagggaatt tagatagaag ggagccaata ggatgaagct gaccatcaga gatatcgcag
    25801 aaatggcagg cgtatcagta acaactgtct cacagatttt gaataacaaa ggaagcagat
    25861 ttagtgataa gacaagaaaa aaagtgttgt cgatcgtgaa tgaacatcat tataagcccg
    25921 attatttcgc ttcaaatgtg atcaatcgac attcaaagac catcggaatg atcgtccctg
    25981 atgtcactga tttcttcttc tccaaactga tcgaaggtgt agagagctat ttgaatcctt
    26041 tgggctatgt gatcatgtta tgcaattctc gtcatagcca agaaaatgag atcaagtatt
    26101 tacaagagct ttcccaccgc tcagtggacg gaatcttgct ggccacacca aatattttac
    26161 ctgagaaata tgcattagac agcggttttt atcaaaaaat gccaatcatt ttaatcgatc
    26221 gcggattgaa tcgtcgggat aacggacggc ttatcgtaaa ggaatatgag ggcgcctatc
    26281 aagctgtttc gctgtttatt gaaaatggcc atacgaagat cggcatgctg aaggaaacca
    26341 ctggatacta tcaattagaa gaacgtttca acggatatcg tcatgcgctg aaagatcatg
    26401 gcctgccttt taatgggaaa tttgttgaac atggagagtt gactgtccaa ggtggatata
    26461 ctgcatcaaa aaaattactc aaacataaag atatcacggc tattttttgc gggaatgatg
    26521 ccatggcgat cggatgctat caggcgatcg atgaattggg caaaaaaatc ccagaagata
    26581 tctcagtcat aggattcgat ggattaaagc tgtcagaata catgattccg caattgacga
    26641 cagtgcagca gccaagtttt gatattggat tttatgctgc acgtttcctg atcgatacga
    26701 tcgaatttcc tcaaagaaaa gttccgaaca aagtgttcga aacaaaatta attattcgtg
    26761 agagcgtaaa agtattgaca aagggctaac tcggcggtat attgcttatg taagcattta
    26821 caaaggctag ttagtgcttt ttttattttt agtaaaccag tttactaaag tggtttacct
    26881 ttcctaaaaa taatgtataa taccgaatga agacaaggag gatcaggcaa tgcgaatggt
    26941 ggatctgatt gaaaaaaaga gggatggaaa cgagctgtcg aaagaggaaa tcgagtacat
    27001 cgtcacgaac tatacgaatg gaaagattcc agattatcaa gtcagtgcat tattgatggc
    27061 aattttttat caagacatga caaatgaaga aatcacgaac ttaacattgg cgattgctaa
    27121 ttctggtgat gtcatcgatt tgagttctct tgaaggaata aaggtagata agcattcgac
    27181 aggtggcgtt ggtgacacga ccacattgat tttagccccc ctagtagcta gtgtcggagt
    27241 gacagtggct aaaatgtctg gacgcggtct aggttacaca ggtggtacac tagacaagct
    27301 agaagcaatt cccggatttc agatcgagct ttcggatgaa gaatttgtac gcattgttaa
    27361 tgaaagtaaa gtagcggtaa ttggtcaatc aggaaacttg gcaccggcgg acaaaaaatt
    27421 gtatgccttg cgtgacgtca cagcgaccgt tgattctctt ccgctgattg ccagttcgat
    27481 tatgagtaaa aaaatcgcgg caggagcaga tgcaatcgtt ttggatgtga ccactggaga
    27541 cggtgctttc atgaagaaca tcgaagatgc aagacgtctg gcaaagacca tgacgagcat
    27601 tgggaaactg gctaaccgag aaacagtggc ggttatctca gatatgtcag aacctcttgg
    27661 cgaagctatc ggaaatagtc tagaagttgt cgaggcaatc gaaacattac aaggaaatgg
    27721 tccagaagat ctagtagaaa tgtgctacgc cttaggaagc caaatggttg ttcttgctgg
    27781 caaagctaag acaaccgatg aagcaagaac gttgcttcaa gaagctctgg aatcaggtaa
    27841 agcgttagca aaattcaaag aaatgatcca aaatcaaggg ggagacccag cgatcgtgga
    27901 acatccagaa cgaattttga ctgcacgcta cacaatggag cttcctgcta aacaaagcgg
    27961 agttgtgtca aaaatcgtgg caaatgaatt aggaattgct gcaatgatgc taggtgctgg
    28021 gcgtaaaacc aaagaagaag atattgatca cgctgttgga ttgaaactgc ataaaaaaat
    28081 tggtgacact gtgacaaaag gtgagtcact attgacgatc tatagtaacg acgaagaaat
    28141 cacttctgtc attgaattat tatataaaaa tattgaaatt ggtgaatcgg caatgaagcc
    28201 aacgttgatt catgacatca tcacagaata aaggaaaaaa gcggacttta ccgttttaaa
    28261 gaaaagggga aaagaaatgg aactaaaccg aatgatcgac catactattt tgaaagcaga
    28321 cgcatctaaa gaagctgtga tgcaaattat cgaagaagca aaaaaatacc atttttattc
    28381 tgtctgcatc aatccagcat gggttgcgct agcgaaagaa caattacaag gtgagccagt
    28441 agccgtatgt acagtaatcg ggtttcctct aggagcaaac acacccgaga caaaagcatt
    28501 tgaaacaaca gatgccatca ataacggtgc agatgaagtc gatatggtca tcaatatcgg
    28561 tgctttgaaa tcaaaggatg atcaacaagt ccaaaaagat atcgaagcag ttgttgaagc
    28621 agcaaaagat cgtgcgcttg tcaaagttat tattgaaaca tcgttattag atagagaaga
    28681 aatcatccga gcttgcgaaa tagcaaaagc tgcaggcgct gattttgtca aaacatcaac
    28741 tggtttctca acaggcggag caaaggtaga ggatgtccgt ttgatgcgtg aaactgtagg
    28801 accagaaatg ggtgtcaaag cttccggcgg tatccataac gaagaagaag caatggcaat
    28861 gatcgaagct ggtgctacaa gaatcggaac aagcgcagga gtagcaatcg tatctggttc
    28921 aactggtgaa ggctattaat tttttcaaag gagaagctca tggcagaact caaacaagaa
    28981 tggatcaaca cagctattga agcgttagat aaagcctatg ttccttattc ccattttccg
    29041 gtaggcgctt gtctcgtaac ggaatcaggc aagatttatc aaggcatcaa cattgagaat
    29101 gcatcatttg gattaacgaa ttgtgccgag cgcacagctt ttttcaaagc agtatctgaa
    29161 ggagaaaaaa catttacgca tctagtcgta gcggggcaca cccccgatcc tatctctcct
    29221 tgtggtgcat gtcgacaagt aatggcagaa ttctgttccc ctgatatgcc ggttacgcta
    29281 gtaggagaca atggtgtgac gaaggcaacg accgttcgtg cactgctgcc ttatgcattt
    29341 actgaaaaag atctataact catgttcatt cagtcagctg actgttgaaa aataaaacaa
    29401 ttattttagg aggctttaca gaaatgaaaa aagcaaaatt atttggttta ggtgctgtcg
    29461 cactagcagc agggttattt ttaggtgcat gcggcaacaa cggctctact gattcatccg
    29521 gtggcaaaag ctcatcagac acaacaactg cagcattgat cacagacaca ggtggtgtag
    29581 acgaccgttc attcaaccag tcagcttggg aaggactaga aaaatggggg aaagatcaag
    29641 gactttcacg aggaaatgat ggcttccaat atttccaatc ttcaaatgaa tcagattaca
    29701 tcccaaatat tgaccaagca ttgaatgctg gattcaaaac gatttttggt attggttata
    29761 aactaaaacc agcgatccaa gaacaagcaa caaacaatac aggtacgaac tttgttatta
    29821 tcgatgatgt catcgatgga ttagataacg ttgtatctgc aactttcaaa gacaacgaag
    29881 cttcttatct tgcaggtgtt gcagcagctt atacgactga aacaaacgta gtcggcttta
    29941 tcggcggtgt aaaaggtgaa gtaatcgatc gttttgatgc tggattcaaa gccggtgttg
    30001 atgcaggtgc gaaagaatta ggaaaagaaa tcaaagtatt gaatcaatat gctggtgact
    30061 tctctgctcc agataaagga cgttcaattg ctcaaggtat gtatgcacaa aacgcagata
    30121 tcatcttcca tgcttcaggc ggtacaggta acggtgtatt ccaagaagca aaatcattga
    30181 acgaatcagg cgacaaaaaa gtttgggtta tcggtgttga ccgcgaccaa tcagacgaag
    30241 gcgaatacac attaaacggc gaaaagaaaa acttcacatt gacatctaca ctgaaagcag
    30301 ttggaacagt agtagaagat ttggcacaaa aatcagcgga cggtaaattc cctggcggcg
    30361 aacacactgt ttatggattg aaagaagacg gtgttggtct aacagaagga caactttctg
    30421 acgaagcgaa aaaagcagtt gatgaagcaa aagaaaaaat catttcaggt gacgtaaaag
    30481 ttccagaaac tcctgaagaa aactaaaacc atttctatag ccttgttaga cacatgtttg
    30541 acaaggctat ggtttgatta gaacaagaat tgttcattta tccaagctgc cttgtgacag
    30601 tttggataag ggaacaactc cctgaagtaa tgtttgtttc aaaagaagaa cgctcactaa
    30661 gcgtgaatct tagtcaatcg ttgccctaga tagaaatcgt taggatgtga aaaaaaggtg
    30721 gttcaagaaa atattgtcat agaaatgcag aatattacca aagaatttgg aacattcaag
    30781 gcaaatgaca acatcaattt acaagtaaag gcaggagaaa ttcatgcgtt gcttggagaa
    30841 aacggtgctg gcaaatctac attgatgaac gtgctttccg gattattaga gccgacatca
    30901 gggaaaattt tgatgcgtgg gaaagaagta aagatcacaa gtccgaccaa agccaaccaa
    30961 ttagggattg ggatggtcca tcagcacttt atgcttgttg atgcctttac tgtaacagaa
    31021 aacatcgtgt tgggaagcga gcctagtcgc gcagggatgc ttgaccataa aaaagcacga
    31081 aaagagatcc aaaaagtttc tgaacagtat ggattgtcag tcaacccaga tgcttacgtt
    31141 cgtgatattt cagttggaat ggaacaacgg gtagaaattt taaaaacact ttaccgagga
    31201 gcagatgtac tgatttttga tgagccgaca gctgtattga cccctcaaga aattgatgaa
    31261 ttaatcgtga tcatgaagga attagtcaaa gaaggcaagt cgatcatttt gattacgcat
    31321 aagttagatg aaatcaaagc agtagctgac cgctgtacag ttatccgccg tggaaaagga
    31381 atcggtacag tcaacgttaa agacgtaacc tcacaacaat tagccgatat gatggttgga
    31441 agaacggttt cattcaaaac gatgaaaaaa gaagcgaagc ctcaagaagt cgttttgtct
    31501 attgaaaatc tagtggtgaa agaaaatcgt ggattagaag ccgtgaaaaa cttgaactta
    31561 gaggttcgtg ctggcgaagt acttggtatc gctggaatcg atggaaacgg gcagtcggag
    31621 ttgatccaag ctttgactgg tttgcgaaag gcagaaagcg gacatatcaa gctaaaaggg
    31681 gaagacatca ctaataaaaa accccgaaaa atcactgaac atggtgtagg acacgtgcca
    31741 gaagaccgtc ataaatacgg gttagtccta gatatgacat tatctgaaaa tatcgcacta
    31801 caaacctatc atcaaaaacc ttacagtaaa aacggcatgc tgaattattc agtaatgaat
    31861 gaacatgcca gagaattgat cgaagaatat gatgttcgaa caacgaatga acttgttccc
    31921 gcaaaagctt tatcaggcgg aaatcagcaa aaagcaatta tcgctcgtga agtcgaccga
    31981 gatcctgatc tgttgattgt tgcaaatcca actcgtggac tggatgtagg tgcgatcgaa
    32041 tttattcata aacgtctgat cgaacaaagg gacaaataca aagcagtgtt actgatcagt
    32101 ttcgaattag aagaaatttt aaatgtttcg gatcgtattg ctgttatcca tgaaggagaa
    32161 attgtcggta tcgttgatcc gaaagaaaca tctgaaaatg aattaggtct attgatggcg
    32221 ggctatacct tagaagaagc acgaaaagag ttagaaaagg gggctggcgc acatgaatga
    32281 tcgcagcgaa aaattccgta atttattagt gcctgtactt tcagttgttt taggattgat
    32341 cttaggcgcg atattgatgg ctgcttttgg ttttcagccc atccaaggtt attcttctat
    32401 gctagatgca gcccttggtt cgcaaagagg gataggtgaa acgttaaggc aagcaacgcc
    32461 gttgattttt acagcattag gtttttctgt agctaactca gctgggtttt tcaatattgg
    32521 gctttctgga caagcacttt gcgggtggat cgtcagtgtc tgggtggcac ttgcgtttcc
    32581 agatctgcca aaagttgttt tgcttccgtt atgcgtgatc ttaggtgcct tagctggtgc
    32641 gatggcagcg gctgttccag gtttacttcg agcatttttt ggaacaagtg aagtgatcgt
    32701 aacaatcatg atgaactata tcttattata cgtaagcaca tttgctttac atgaagtgat
    32761 gcctgaaagc tatcgctcaa gtttggactc ttccaatatg atcagtcaaa atgcctcact
    32821 gcggttacca tggttaacac aagcttttgg cggctctcgc gtaaactcag gattattttt
    32881 agcaatcatc gcgcttattt tcgtttggct gctgatgaag aaaacgactt taggatttga
    32941 aatccgttct gttggattga atccttttgc ttctgagtat gcaggaatga gtagtaaacg
    33001 tacgatcgtt ttgtcgatgg tcatttctgg cgctttggca gggcttggcg gtgtggttga
    33061 aggattagga acgtatcaaa acttctttgt tcaaacgact tcgctatcta ttggatttga
    33121 cggaatggct gtttccttgc ttggttctgg atcagcaatc ggtattcttt tatcagcgat
    33181 cttgttcagt attttgaaga tcggtggact tggcatgcag acaggagcag gtgttccgtt
    33241 tgagatcgtc aatgtatcga ttgctttgat tatcttcttt gtcgggatca acttcctgat
    33301 tcgtttcgtc atggctaaag tcttccaagg gaaaaaacaa gaagagatcg ttgcgacaat
    33361 agaatcgaaa ccaacgaatc aaaaccatga agggggcgaa ctataatgtc gactatcgaa
    33421 ttaattgcct tgatccttac ttctacactg gtttattcaa caccgctaat tctaacgtca
    33481 ctaggcggaa ctttttctga acgaagcggg atcgtaaacg tagggctaga gggaatcatg
    33541 gtcatgggtg cttttagttc catcgttttc aacttgacga tgagtccatc acttggttct
    33601 atgacaccat ggatcgctat tttagtgggt ggcgtcgtag gtatcctatt ttctctgatt
    33661 cacgcagtag caacagtcag tttgcgtgct gaccatatta tcagcgggac agtaattaat
    33721 ctgatggcac ctgctttagg tgttttcttg atcaaagcat ggtatggtaa aggtcaaact
    33781 gataacatca cgcagaatct ggggtatttt tctttcccag gattagcaga tattccggtc
    33841 attggaccaa ttttctttaa aaatacattc ttacctgctt attgtgctat tttgattgct
    33901 gtcctagctt gggtgatcat cttcaagacg aaattcggct tgcgcctccg ttcagttggt
    33961 gaaaatcctc aagctgccga cacattaggt atcaatgtat atgctatgcg ttattcaggc
    34021 gtactgattt ctggcttgtt aggcggtatg ggcggtgctg tttttgctca gtcgatttcc
    34081 ggtaactttt cagctggtac gatcgttgga caagggttca tctccatggc tgctatgatc
    34141 tttggtaagt ggaatccttt aggggcaatg ggtgcctcat tgttctttgg ttttgctcaa
    34201 agcttgagta tcattggcgc acaattacca gttatttctt cgattccgcc agtattgctg
    34261 caaattgctc catatttgct gacaatcatt gtgctggttg ttttcttagg gaaagcttct
    34321 ggtccaaaag caaacgggaa gaactatatc aaatcaaaat aatcttttag cgaataaaaa
    34381 gggtgggtta cgggaagtgt ttttcgtctc gccctttttg ttttaaaggc aataaaaata
    34441 aaaagaaaga aggaataatc atgtttaaac gcgtacatct gatcgtcatg gattcagtag
    34501 gaattggaga agcaccagat gccgataagt tcggtgatgt tggttctgat acattaggac
    34561 acattgcgaa agaagcagga ttgaacgttc cacatttaga gcagcttggt ttaggaacga
    34621 tccgtcctct tgaaggtgtg gaatcagtga aagatcatca aggctatgcg acgaaattag
    34681 aagaagtttc tgtagggaaa gatacgatga caggccactg ggaaatcatg ggattgaata
    34741 tcaaaactcc atttcgtgtg tttcctaatg gattccctga tgatctgatc aaacaaatcg
    34801 aagaattttc tggccgtaaa gtcgtatgta acaaacctta tagcggaaca gctgttattg
    34861 acgattacgg tgaacaccaa atgaaaacag gcgatttaat tgtatatact tctgccgatc
    34921 ctgtccttca gatcgcggca catgaagaaa tcattccttt agaagaatta tatcggattt
    34981 gccaattcgt tcgtgatata acaaaagatg atccgtatat gattggccga atcattgcac
    35041 gtccgtacgt gggtgaacca ggagacttca cacgaacaag caatcgccat gattatgcgt
    35101 tgaatccatt cggacacaca gtccttgatt ctttgaaaga agcaggaaag gacgtgattg
    35161 ctgttggaaa gatcaacgat attttcaacg gacaaggaat cactgaatct gtccgcacga
    35221 aaagcaatat ggatggcgtt gaccagctgc tgaaagttat gaaaaacgat ttttcaggaa
    35281 tcagctttac caatttagta gattttgatg cattatacgg tcatcgtcgg gatgtagtcg
    35341 gctatgcgca tgcgattgaa gaatttgact tacgaattcc agaattgctt gaagcgatgg
    35401 aagaagacga cttgctaatg attacagccg atcacggaaa cgatccgacg tttactggta
    35461 ccgatcatac gcgagaatat gtaccgttat tggtttacag taaaaaaatg aaagaacaag
    35521 gggcattgcc tcaaggatat tattcagata tttcagcaac gattgctgag aactttagtg
    35581 tttcttcgac tgaaaatggc gaaagcttct tgaaattatt aaaataatct ttttaaatag
    35641 gagaaagcaa atgaccaagt taagcgagat gttacaagaa acgacccagt ttatccttga
    35701 taaaggagta aaagaaattg attttggttt gattctaggt tcaggattag gtgaattagc
    35761 agatgaaatc gaagatgctg taatgatttc ttatgatgag atcccgttct ttcctgtttc
    35821 gacagtagtt gggcatgcag gaaagctagt ttatgggtct ctggcaggca agaaagtgtt
    35881 agccatgcaa gggagattcc actactatga aggtcattcc atgcaaacag tgacctatcc
    35941 agtacgtgtg atggccggac taggggccca ttcagtcatt gtgactaatg catgtggtgg
    36001 tgtcaacgaa tcatttgtac caggagattt gatgctgatt accgatcata tcaattttac
    36061 tggtgaaaat cctttgatcg gtccgaatga agatgcaatg ggccctagat ttccagatat
    36121 gagtcaagct tatacgcctg actatcaagc aacagcaaaa gcagcagcag aaaaactagg
    36181 tttggatctt aaagaaggcg tatatatggg ctattctgga ccaacttatg aaacgcctgc
    36241 ggagatccga atgtctcgga caataggagc cgatgcagta gggatgtcga ctgttccaga
    36301 agtcatcgta gcagctcaca gcggattaaa agtgttagga atctcttgta ttaccaactt
    36361 agcagcaggt atgcaagcga atctgagcca tgaagaagtt gtagaaacaa ctcagagagt
    36421 caaacaatct tttaaagcat tggttaaaga aacattgaca ttattgtaat aggaggaaca
    36481 ataaaatgag tgtgcatatt gaagcgaaag aaggcgagat cgccgataag attttacttc
    36541 cgggagatcc tttgcgagct aaatatattg cggagacttt tttggaagat ccagtttgtt
    36601 acaatcaggt acgcggtatg ttaggcttta ccggcaaata taaaggagaa cgtatttctg
    36661 ttcaaggaac aggaatggga atgccatcag ccaccatcta tgcccatgaa ttgatccagt
    36721 cgtatggtgt aaagaaattg attcgagtag gtacatgcgg tgcattgtca aaagacgtcc
    36781 atgttcgtga tttagtacta gcacaaggtg cagcgaccag ttcttcgatg atcgaaaaaa
    36841 atttccaagc ctttcatttt cctccaatca gtgatttcaa tctattactg aaagcatatg
    36901 agatagctaa agaaaagggc tatacggttc atgtaggaaa tgttctttcg gaagattctt
    36961 tctacaaaga tgatttgaca gagacgttcc aattagctga acttggcgtt ttaggagtgg
    37021 aaatggaagc agcggctctt tattacttag gcgcgaaata ccatgtgcag acattaagtt
    37081 tgatgaccgt tagcgaccat ttgatcaccg gtgaagaaac aacagctgca gaacgtcaat
    37141 ctacgttcaa tgaaatgatc gaagtaggat tggaaacagc gatagcagaa taagaaggaa
    37201 atgaaaaagc tgccctgcat taagtaataa gaacatccaa gcaaaaatag ctcctcatgt
    37261 ttttgacttg gctggactta ttattgcaaa tgtaagcttt tgaacaccgt ttaccaagag
    37321 gttgtgaatc tgccgtttaa ctctgagtca caaggaacaa tttcaaaaaa cagcttttca
    37381 tgtttgatga atattgtgac ttgtgaccga gaagttggca ggagaaaacc gtttatacga
    37441 aaaaagggac tgtgacaaat cgtgtcacag tccctttttt atagtgtttt ttataggtag
    37501 tattttttag caactgttaa gtcatcattt aattcataaa caagtggttg acctgttgga
    37561 atttcaagat ccatgatgtc ttcgtcagag ataccttcga tatgtttagc tagggcgcgt
    37621 aatgagttac catgtgcagc tactaaaaca gttttgttgt ctagtaatgc tggagcaatt
    37681 tcatcttgcc agaatggcaa agcgcgttct aatgtcactt tcaagttttc tccaccagga
    37741 atatcgcgtt tgtctaacat tgcgtaacga cggtcatttg ctgcagaacc ttcgtcagtt
    37801 tcttccatta atggaggaag agtatcgtaa gaacgacgcc agatgtgcac ttgttcgtcg
    37861 ccgtattttt cagctgtttc ttttttgttc aaaccttgta atttaccata gtgacgttcg
    37921 tttaagcgcc atgatttgat ttgtggtacc caaagttgat ctgaatattc taagatcaag
    37981 ttacatgttt tgattgcacg agttaaaaca gaagtgtaag caacatcaaa ttcgattcca
    38041 gcttctttga ttttgcgtcc gccttctttt gcttcttcga ttccttctgg tgctagattt
    38101 acatcagccc aaccagtaaa ttggttcaat gcattccatt cactaagacc gtgacgagaa
    38161 aaaactaatt ttggcatgtt tagctctcct tttaagatag gtttatattt ctgaaatttt
    38221 cagttctgtt ttattgtaca attttttgga agagatttcc atcgaaaaat tagataagat
    38281 tctatgagaa aacaagtaga gaatataaaa aaacgaacag tgcccacgca actgttcgtt
    38341 tttaggtatt agatgcataa ttgctcgatt tctttttcag gtaaattgat atatttataa
    38401 catgttccaa ctgaaacacc gcattttgaa gaaataaatt ggatcgtttc ttttttttca
    38461 taatagagac gtcggatttt tttgatcgtt tttgcatcga tttttggtct tccgccgatt
    38521 tttccttttt tacgagcttc atctaatcca actaatgtac gttctttgat caatgcgcac
    38581 tccatgtttg ctaggttttc cattaattgg aaatagattt ttcccatttc gcgcgtatcg
    38641 attccttcat caagactaat caagtgcagc ccgcgatctt tgaataattg cgtgagttct
    38701 gttaattgcc gcgtagattt gcctaatcga tgaagttggc aaatgactag tgcatcgcct
    38761 tgttgcatgt cagcgatcac tgactccaaa tgaacagcag tagaatcatt ttgttccact
    38821 tcatatgtct catggaaaat ttcttgacaa ccaaagtcag ataattgatc aacctgagtt
    38881 gttaaatcaa cgtcatttat ggttgtgcgt gcataaccaa taattttcat ggtgattcct
    38941 ttctagcagt gattttctaa ctggatataa cagtaaaaat gtagcataaa gtacgtcaaa
    39001 aagatagttt tttcgcaaat tttccgctgt ctttttttat tggatgatca agcagttttt
    39061 ctttatttac gacggattgc gtcaagaatc tcaacgcctt tttctgagcc gacaactact
    39121 ttagaaacca tgtttaggaa aagcccatgt tctactaccc caacaagttc atctaaatag
    39181 gtagctaagc tttctggctg ttcgatgact tctagatgca gatcaatgat gtaatgacca
    39241 ccatctgtgg ttaagacttc tccgttttcg tctgtacgca agacgggttg gaatcttttt
    39301 tcttcaaaaa tatgaagtag ctgttgggag ccataaggga tcacttcaac tgggagtggg
    39361 aacttcccaa gtttatcgac taatttagaa gaatcaacga tccaaatcgt ttcttttgag
    39421 tacgtagcga ctattttctc gaaaagcaaa gcagcgccgc cgcctttgat cccttgaaaa
    39481 tcagcactga tttcatcagc accgtctatt gtcaaatcga ctacggggac ttcatcaata
    39541 ctctttaacg gtattcctaa tttttccgct tgttcttttg tcgcatttga agtagtaact
    39601 cctgtgatac gtaaaccttc ttcacgcata cggcgaccaa tctcttctac catataatag
    39661 gcggttgaac cggtcccgag acctacgatc atcccgtcct ttacgaattt cgcggcttca
    39721 atgccagcta attgttttaa attcatcttt gcgtccacct ttttttagtt tgagcatcgt
    39781 gctttcctca ctattttagc gtgatttacg gtaaaaagat accattcttt tttattccaa
    39841 taaagctttt tcaaaaaaaa ttgcatctct tgttgacatg ttttttcatt cgtgatattc
    39901 taacaaaggt gctttatcta caggtttctg tgaagaaacg tgctgactgt ttatcaaagc
    39961 atatttgata aggatgcaga cattgcattt attttttatc acaaaaaaag aaccacctgg
    40021 atgtgtggaa ctagacgcaa atcgtgggaa ggaggaaaca aggaatgcct acaattaacc
    40081 aattagtacg taaacctcgt aaatcaaagg tggaaaaatc taattcacct gctttgaaca
    40141 aaggatataa cagctttaag aaaactcaaa ctaacgtaaa ctcacctcaa aaacgtgggg
    40201 tagcaactcg tgtgggtaca atgacaccta aaaaaccgaa ctcagcttta cgtaaatatg
    40261 cacgtgttcg tttgtcaaac ttaattgaag ttactgctta tatcccaggg attggtcata
    40321 acttacaaga acacagtgtt gtattattac gcggtggtcg tgtaaaagac ttaccagggg
    40381 tacgttacca tatcgttcgc ggtgctttag atactgctgg tgttaacgac cgtaaacaaa
    40441 gccgttctaa atacggaact aaaaaaccta aagcttaatt ttaattatta aacaaatgaa
    40501 acttgcttct actatataga agtaattact atgaacaata tttcggaagg aggagttacg
    40561 gatgccacgt aaaggtcctg ttgcaaaacg tgatgtttta ccagatccta tttataactc
    40621 aaaattagta actcgcttga tcaaccgtgt aatggttgac ggaaaacgcg ggattgcagc
    40681 taacattatc tataatgcct ttgacttgat caaagaatct acaggtaacg atccattaga
    40741 agtgtttgaa caagcaatga aaaacgttca acctgttctt gaagttaaag cacgtcgtgt
    40801 tgggggttca aactaccaag taccagttga agttcgccct gaacgccgcg ttactctagg
    40861 tcttcgttgg gtagtaaact acgctcgctt gcgcggtgaa cacacaatgg aagaacgctt
    40921 agcaaaagaa atcatggatg ctgcaaacaa cacaggtgct tctgttaaaa aacgtgaaga
    40981 cactcataaa atggctgatg ccaaccgtgc gtttgctcac tatcgctggt aagattctct
    41041 ctgtttggtc ggcttttata agtcgacctc agatagtgtc cttattttta gcaactagat
    41101 agtaaagaga ggagaaacaa ggagaatgac cagagaattt tctttacaaa acactcgtaa
    41161 tatcggtatc atggcccaca tcgatgctgg taaaacgact gctactgaac gtatcttgta
    41221 ctatactggt aaaatccata aaattggtga aactcatgaa ggagcttcac aaatggactg
    41281 gatggaacaa gaacaagaac gtggtattac gatcacttct gctgctacta cagcacaatg
    41341 gaagggtcac cgaatcaaca tcatcgacac accaggacac gtagacttca cagttgaagt
    41401 tgaacgttca ttgcgtgtac ttgatggtgc tgtaactgtt cttgatgcac aatcaggtgt
    41461 tgaacctcaa actgaaacag tttggcgtca agcaacaact tatggtgtac ctcgtatcgt
    41521 atttgcaaac aaaatggaca agatcggtgc tgacttctta tattcagtat caactttaca
    41581 tgaccgtttg caagcaaacg ctcacccaat ccaattacca attggtgcgg aagacgactt
    41641 cacaggaatt atcgaccttg taacaatgaa ggctgaaatg tatacaaacg atcttggaac
    41701 agagatcgaa gaaacagaaa ttcctgaaga ataccgcgaa ttagctgaag aatggcgcga
    41761 aaaattggtt gaagctgtag ctgaaactga tgaagaactt actttgaaat acttagaagg
    41821 tgaagaaatc actgaagctg agttaaaaga aggtatccgc cgcgcaacag ttaacgtaga
    41881 attctaccca gtactatgtg gttcagcatt taagaacaaa ggggttcaat tactattgga
    41941 cgctgttctt gattacttgc catcaccgtt agatatccca gctatcaaag ggattgaccc
    42001 taaaactgat gaagaagtag aacgtcctgc agacgacagc gctcctttct cagctttagc
    42061 atttaaagtt atgactgacc cattcgtagg tcgtttaact ttcttccgtg tgtactctgg
    42121 tgttttacaa tcaggttcat acgtacaaaa cgcaacaaaa ggcaaacgtg aacgtgttgg
    42181 tcgtatccta cagatgcatg ccaactctcg ttcagaaatc tctgaagttt acgctggaga
    42241 tatcgctgct gctgttggtt tgaaagacac aactactggg gacacactat gtgatgaaaa
    42301 gagtctagtt attcttgaat ccatggaatt cccagaacca gttatccaag tcgctattga
    42361 acctaaatca aaagctgacc aagataaaat gggtgtggct ttacaaaaac tatctgaaga
    42421 agatcctact ttccgtgctg aaacaaacgt ggaaacaggc gaaacaatca tcgctggtat
    42481 gggtgaactt cacttagata tcatcgttga ccgtatgcgt cgtgaattca aagttgaagc
    42541 taacgtaggt gcgcctcaag tatcttaccg tgaaactttc cgtgctggca ctcaagccga
    42601 aggtaagttt gtacgtcagt ctggtggtaa aggtcaatac ggtcacgtat ggattgaatt
    42661 tacaccaaat gaagaaggtg ctggtttcga atttgaaaat gcgatcgtcg gtggggttgt
    42721 tcctcgtgaa tacattccag ctgttgaaac tggtttgaaa gatgctatgg aaaatggtgt
    42781 cttagctggc tatccattag tagatatcaa agctaaactt tacgatggtt cataccatga
    42841 tgtcgattca aatgaaactg ccttccgtgt tgctgcttct atggcattac gtgcagcagc
    42901 taagaaagct aatccagtaa tccttgaacc aatcatggct gtagaagttg ttatccctga
    42961 agattattta ggtgatgtta tgggtcacgt aactgctcgt cgtggacgtg ttgaaggtat
    43021 ggaagctcgc gctggcggcc aacaagttgt tcgtgcgatg gttccacttg ctgaaatgtt
    43081 tggttatgct acaactcttc gttctgctac tcaaggtcgt ggtacattta caatgacatt
    43141 tgaccactac gaagatgtac caaaatcagt acaagaagaa atcattaaga aaaacggcgg
    43201 aaaagctgaa taatttctta aaaccggata gtcctgcaaa gagattatcc aaagagacta
    43261 tatttttaat atagtttcgt gtaaaataat tatcgatgat atgggcatgt ggtgtacctt
    43321 gtgtacatca tatacctatc agacaaataa aaaatatatt gtatttttag gaggacattt
    43381 taaaatggca aaagaaaaat ttgaccgttc taaaccacac gttaacattg gtactatcgg
    43441 acacgttgac catggtaaaa ctacattaac agctgcaatc acaactgtac tatctaagaa
    43501 aaacggcggc caagctatgg cttacgatca aatcgatggt gctccagaag aacgcgaacg
    43561 cggaatcaca atctcaacag ctcacgttga gtatgaaaca gatacacgcc actacgctca
    43621 cgttgactgc ccaggacacg cggattacgt taaaaacatg atcactggtg ctgctcaaat
    43681 ggacggagct atcttggtag tttctgctgc tgacggccca atgcctcaaa ctcgtgaaca
    43741 catcctattg tctcgtcaag ttggtgttcc ttacatcgtt gtattcttga acaaagtaga
    43801 catggttgat gacgaagaat tactagaatt agttgaaatg gaagttcgtg acctattaac
    43861 agaatacgaa ttccctggtg acgatgttcc tgtagttgct ggatcagctt tgaaagctct
    43921 agaaggcgac gcttcatacg aagaaaaaat tcttgaatta atggctgcag ttgacgaata
    43981 catcccaact ccagaacgtg acaacgacaa accattcatg atgccagttg aagacgtgtt
    44041 ctcaattact ggacgtggta ctgttgctac aggtcgtgtt gaacgtggac aagttcgcgt
    44101 tggtgacgaa gttgaagttg ttggtattgc tgaagaaact tcaaaaacaa cagttactgg
    44161 tgttgaaatg ttccgtaaat tgttagacta cgctgaagct ggagacaaca ttggtgcttt
    44221 actacgtggt gttgcacgtg aagacatcca acgtggacaa gttttagcta aaccaggtac
    44281 aatcacacct catacaaaat tctctgcaga agtatacgtg ttgacaaaag aagaaggtgg
    44341 acgtcatact ccattcttca ctaactaccg tccacaattc tacttccgta caactgacgt
    44401 aacaggtgtt gttgaattac cagaaggaac tgaaatggtt atgcctggcg acaacgtaac
    44461 aatggaagtt gaattaatcc acccaatcgc tatcgaaaac ggtactaaat tctcaatccg
    44521 tgaaggcgga cgtacagttg gtgccggtgt cgttacagaa atcaaagctt aattcactta
    44581 agttttaaag taaagcaaca tttattcgga cgtaatcgct cggaacgaag gtcttaggat
    44641 ctttgttccg agctttttta tttattgcag gatcaggaaa aaagacagga gtattataaa
    44701 tagaagaaac acgaaataaa agagtcagta ttttctaaat gaaactttat gaaaacaaaa
    44761 tgttttttac aagaaaaagc cttgctttgt gagtttatat atattataat gacaaaggtg
    44821 cgtttacttt agtgaattgc acagacgtaa tcagaatgat ttcgtcggct aagaaacgag
    44881 aggttgcgac acgcccggac gctttgccac gaacgagcgt gacggaaatt ttcgtggagc
    44941 tatgtctact tttcaaaata ggcgaaggag ggaacaagat ggcaaaacaa aaaattcgta
    45001 tccgtttaaa agcgtatgaa caccgtattt tagatcaatc agcggataaa atcgtggaaa
    45061 ctgcaaaaag aactggagct agcgtgtctg gtccaattcc attaccaact gaacgcagtc
    45121 tttacacaat catccgtcat aaatacaaag attcacgcga acaattcgaa atgcgtacac
    45181 acaaacgtct tatcgacatt gtgaacccaa caccaaaaac tgttgatgct ttgatgaagc
    45241 tagacttacc atctggtgta aacatcgaaa tcaaattata aaactaaaac aaaaataatg
    45301 gaggtgtact catgaccaaa ggaatcttag ggaaaaaagt gggaatgaca caaatcttca
    45361 ctgaatctgg tgaattaatt ccagtaactg ttgtagaagc tactccaaac gtagtactac
    45421 aagtgaaaac aatggaaacg gatggctacg aagctattca agttggttac caagatatgc
    45481 gtgaagtttt atcaaacaaa cctgcgaaag gtcatgttgc aaaagcaaac acggctccta
    45541 agcgcttcat tcgtgaattc aaaaatgttg agctaggaga atatgaagta ggaaaagaaa
    45601 ttacagtaga tgttttccaa gcaggagaca ttattgatgt aacaggtact acgaaaggta
    45661 aaggattcca aggggttatc aaacgccacg gacaaagccg cggaccaatg gctcacggtt
    45721 ctcgttacca tcgtcgtcct gggtcaatgg gtccagttgc acctaaccgt gtatttaaaa
    45781 acaaacgtct tgctggccgt atgggtggca accgcgtaac tatccaaaac ttggaagttg
    45841 tacgtgtcga tgcagaaaga aatgttatct tgatcaaagg taatgttcct ggagctaaaa
    45901 aatctttaat tactatcaaa tcagctgtga aagctaaata attgtaggaa gaaaggagga
    45961 actaaggaat gccgaatgta gcattattca aacaagatgg aagccaaaac ggtgaaatca
    46021 cacttaacga agaaatcttc ggaattgaac ctaatgaaag tgttgtttac gatgcaatcg
    46081 taatgcaacg tgcgtcatta agacaaggaa cacacgcggt taaaaaccgt agcgctgttc
    46141 gcggcggcgg acgtaaacca tggcgtcaaa aaggaacagg tcgtgcacgt caaggatcta
    46201 tccgctcacc acaatggcgt ggaggtggcg tagtctttgg accaacacca cgttcttaca
    46261 gctacaaact tcctaaaaaa gttcgtcgtt tagcaatgaa atctgtattg tcagaaaaag
    46321 ttgctgaaaa caacttggta gcaatcgaag gcttgaactt cgacgcacca aaaacaaaag
    46381 aattcaaaca agttcttgct aacttatcta tcgactctaa agtattggtt gttctagaaa
    46441 aaggtaacga ctttgctgct ttatcagcac gtaacttacc aaacgtttct gtagtaactt
    46501 ctgataatgt gagtgtgcta gacgttgtat caaatacaaa agtgttagca acacaaactg
    46561 ctcttactca aattgaggag gtgcttgcat aatgaactta ctagacgtaa tcaaacgccc
    46621 agtgatcact gaaaaatcaa tgcttgccat ggatgacaag aaatacactt ttgaagtgga
    46681 cactcgcgca aacaaaactt tagtaaaaca agcggtagaa gctgcttttg acgttaaagt
    46741 caaaaacgtg aacatcgtga acgtacgtgc gaaattcaaa cgtatgggca aatatgcagg
    46801 atatacaaaa aaacgtcgca aagcgatcgt tacattgact gaagattcaa aagaaatcca
    46861 attattcgaa gctgctgaat aagcactaat agataactca ttaaattagg agggaaaaac
    46921 gtggcgatta aaaagtacaa acctacctca aatggtcgtc gtaacatgac aggttctgat
    46981 tttgctgaaa tcacaacatc aacacctgaa aaatcattgt tacaaccatt gaaaaaccat
    47041 gctggacgta acaacaacgg ccgcatcact gtacgtcatc aaggtggcgg acacaaacgc
    47101 caatatcgcg tgatcgactt caaacgtaac aaagataacg ttgttgcaac tgttcaaacg
    47161 atcgaatatg atccaaaccg ttcagctaac atcgcgttag tacactatga agatggagtg
    47221 aaagcttaca tcttagcacc taaaggacta gaagtgggta tgaaacttgt ttcaggtcca
    47281 gaagcagata tcaaagtcgg aaatgctctt ccattagaaa acattccagt tggtactgtt
    47341 atccacaaca ttgaaatgaa acctggtaaa ggtggacaat tgatccgttc tgctggtaca
    47401 agtgctcaag tacttggtaa agaaggcaaa tacgtattga tccgcttgaa ctctggtgaa
    47461 gttcgtatga tcttagctgc atgccgtgct acaatcggtt ctgtaggtaa cgaacaacac
    47521 gaattaatca acatcggtaa agctggacgc tctcgttgga tgcgtaaacg cccaactgta
    47581 cgtggtagcg taatgaaccc taatgatcac ccacacggtg gtggtgaagg taaagctcct
    47641 atcggacgta aagcaccagt ttctccttgg ggtcaaccag ctcttggtta caaaactcgt
    47701 aacaaaaaag ctaaatcaga caaacttatt gttcgtcgtc gcaaaaataa ataattactt
    47761 tgaccatgtg tcgcacattt tgagaggagg ttcaccatgg gtcgtagttt aaagaaagga
    47821 ccttttgtcg atgagcattt aatgaaaaaa gttgaagctc aagcaggggt tgaaaagaaa
    47881 aaagttatca aaacttggtc acgccgttca acagttttcc caagttttgt tggatatacc
    47941 atcgcagttt atgatggacg taaacatgta ccagtttaca tccaagaaga catggtagga
    48001 cacaaattag gtgaatttgc acctacaaga acttatcgtg gacatgctgc tgacgataag
    48061 aaaacgaaac gctaatttga ggggaggata aatccaaatg gcagaacaaa tcacatcagc
    48121 taaagcaact gcaaaaacag ttcgcacttc acctcgaaaa gcccgtttag taattgacct
    48181 tatcagaggt aaaagtgtcg cagatgcaat ttcaatcttg aaattcacac caaacaaatc
    48241 tgctggaatc attgaaaaag tattgatgtc agcagttgcg aatgcagaaa ataactttga
    48301 cttagatgtt gaaaacttgg tagtaagcga agcttttgtt aacgaaggac ctacaatgaa
    48361 acgtttccgt cctcgtgcaa aaggatcagc ttctccaatc aacaaacgta caagtcatat
    48421 cacggtagtc gtatcagaaa aataaggagg gataatcagt gggtcaaaaa gtacatccaa
    48481 ttggaatgcg tgtaggcatc atccgcgact gggatgctaa atggtatgct gaaaaagagt
    48541 atgctgagtt cttacacgaa gatttaagaa tccgtaaatt tatttcaact aaacttgctg
    48601 atgctgctgt atcaacagtt gaaatcgaac gcgcaacagg tcgcgtaaac atttcaattc
    48661 acacagctaa accaggtatg gttattggta aaggcggttc tgaagtcgaa agcctaagaa
    48721 aagaattaaa caaattaact ggtaaaagaa tccatatcaa tatcgtggaa atcaaaaaac
    48781 cagatctaga tgcaaaatta gtaggtgaag gaatcgcacg tcaattagaa aaccgtgttg
    48841 ctttccgtcg cgctcaaaaa caagccatcc aacgctcaat gcgtgctggc gctcaaggga
    48901 tcaaaactca agtatctggt cgtctaaacg gagcagatat cgctcgttca gaaggatact
    48961 cagaaggaac tgttcctctt catactttac gtgcggacat tgattacgca tgggaagaag
    49021 cagatacaac atacggaaaa ctaggagtta aagtgtggat ctatcgtgga gaaattcttc
    49081 caactaaaaa aaacactgag aaaggaggga aataatcatg ttagtaccta aacgtgtaaa
    49141 acaccgtcgt gaattccgcg gaaaaatgcg cggggaagct aaaggcggaa aagaagtagc
    49201 attcggtgaa tacggtttgc aagctgttga ttcacattgg atcacaaacc gccaaatcga
    49261 agctgctcgt atcgcaatga ctcgttacat gaaacgtggt gggaaagtat ggattaaaat
    49321 tttccctcac aaatcttata ctgccaaagc aattggggta cgtatgggtt ctggtaaagg
    49381 ggcacctgaa ggatgggttg caccagtaaa acgtggtaaa atcatgtttg aaatcgcagg
    49441 cgttcctgaa gaagtagctc gtgaagcgtt acgtctagct tctcacaaat taccaatgaa
    49501 aactaagatc gtaaaacgtg aggaaatggg tggtgaatcg aatgaaggtt aaagaaatca
    49561 gagaattaac cactgccgaa atgcttgatc aagaaaaaca attaaaagaa gaattgttta
    49621 atcttagatt ccaattagca acaggtcaat tagaaaacac tgcacgtatt aaagaagtac
    49681 gtaaatcgat tgcacgcatc aaaactgtgt tgcgtgaaca agctaagtaa ttatggaagg
    49741 aggccattaa gcgtatgact gaaggaagaa atcaacgcaa agtttatcaa ggtcgcgtgg
    49801 tttcagacaa aatggataaa acaattaccg ttgctgtcga aacaaagaaa aaccacccta
    49861 tctatggcaa acgcatgaac tattctaaga aatacaaagt gcatgatgaa aacaacacag
    49921 caaaagttgg cgacatcgtg agaattatgg aaactcgtcc attatcagct acaaaacgtt
    49981 tccgtttgtt ggaagtagtc gaagaagcag ttattatcta ataacacgag attttcctat
    50041 atagattgaa tgcaaaatct gaaaggagga tacacaacgt gatccaagca gaaagtcgtt
    50101 taaaagtcgc tgataactca ggcgcacgtg aaattttgac gatcaaagtc cttggtggat
    50161 ctggtcgtaa aactgctaac atcggtgatg tgatcgttgc tacggttaaa caagcaacgc
    50221 caggtggggt tgtcaaaaaa ggtgacgtcg ttaaagccgt tatcgttcga acaaaatcag
    50281 gagctcgtcg tacagacggt tcatatatta aatttgatga aaatgctgca gtgattattc
    50341 gtgatgataa aagccctcgt ggaacacgta tctttgggcc agttgcacgt gaactacgtg
    50401 aaaacaactt catgaagatc gtttcactag caccagaagt tttataatct tgagacactt
    50461 atcaaaggag gtgcgaaaca gttatgtttg ttaaaaaagg cgataaagtt aaagttatca
    50521 ctggaaaaga caaaaacaaa gaaggcgttg tactagcagc gttcccgaaa aaagataaag
    50581 ttattgtcga aggtgtaaat gtcgttaaaa aacaccaaaa accttctcaa gctgctcctc
    50641 aaggtggaat tgttgagatg gaagcgccaa ttcatgtttc taacgtgatg gtggttgact
    50701 ctactggtgt agctggccga gttggctaca aagaagtaga cggcaaaaaa gtccgtgttt
    50761 ctaaaaaaac cggtgaagtt ttagataaat aaaagtttaa ggaaggaggg tcttactgaa
    50821 tgaaccgcct aaaagaaaaa tatcttaaag aagtaactcc atcattgatg gaaaaattta
    50881 actatagctc tgttatgcaa acacctaaag ttgaaaaaat cgtcatcaac atgggtgttg
    50941 gtgatgcggt atcaaacgct aaaaacttag ataaagcagt tgaagaatta actttgatca
    51001 ctggtcaaaa accaatgatt acaaaagcta aaaaatcaat cgctggattc cgtttacgtg
    51061 aaggaatgcc aattggtgca aaagttacat tgcgcggaga aagaatgtac gaattcttag
    51121 acaaattggt ttctgtttca ctaccacgtg tacgtgactt ccatggtgta agtaaaaaag
    51181 cctttgacgg tcgtggaaac tatactttag gtattaaaga acaattgatc ttcccagaag
    51241 tagattatga tttagtagat aaagtacgtg gtatggacat cgttattgta acaacagcaa
    51301 actctgatga agaatctcgt gagttgttga cacaattagg catgccattc caaaaataat
    51361 taaaggaggc gaactacgtg gctaaaaaat caatgattgc taaaaacaaa cgtcctgcaa
    51421 aattttcaac acaagcttat actcgttgcg aacgttgcgg acgtccacat tcagtttatc
    51481 gtaagttcca tctttgccgt atttgcttcc gcgaacttgc ctataaaggt caaattcccg
    51541 gcgtgaagaa agctagctgg taaaaagtaa attcgcataa gaaggaggta aaagatcaat
    51601 ggtcatgaca gatccaattg cagattttct aactcgtatc cgtaacgcaa acatggttaa
    51661 acatgagtct ttagaagtac ctgcatcaaa aattaaacgt gacatcgctg aaatcttgaa
    51721 acgtgaaggt ttcgttcgtg atgttgaata catcgaagat gacaaacaag gcgtgatccg
    51781 tgttttccta aaatttggta aaaacggcga acgtgttatc acaaacttaa aacgtatctc
    51841 taaaccaggt ttgcgtgctt atgtcaaagc tgacgaagta ccaaaagtat tgaacggttt
    51901 aggtatcgca atcatttcga cttctgaagg tgttgtcact gataaagaag ctcgtgaaaa
    51961 aaatatcggc ggcgaagtta tcgcttacgt atggtaatca agtagaatct acaaggaggt
    52021 gtctttaagt gagccgtatc ggaaataaag tcgttgttat ccctgaagga gtaacagtta
    52081 ctcaagacgg aaacaacgtt acagttaaag gaccaaaagg tgaattgact cgtacttttt
    52141 cagcagatat caaaatgaat atcgaaggaa acgaagtaac tttcactcgt ccaaacgaca
    52201 gtaaagaaat gaaaacaatt catggaacaa ctcgtgcgaa cttcaacaac atggttgtag
    52261 gtgtcagcga aggtttccaa aaagcgttag aactaatcgg ggttgggtac cgtgcacaat
    52321 tacaaggatc aaaacttgta ttgaacgttg gttactcaca tccagtagaa atcacaccac
    52381 cagctggagt aactgttgaa gtaccagcta acacacaagt aattgttaaa ggtgcgaaca
    52441 aagaagaagt tggcgaatta gctgcaaaca ttcgtggaac tcgtcctcca gaaccttata
    52501 aaggtaaagg tattcgttat gttggcgaat atgtacgccg taaagaaggt aaaactggta
    52561 aataatcgtt tagaaaaatt gcatagaagc cagcagcagg aaaaaggcat ttggctgaag
    52621 tttaccttca aaaaaataca tttttacttg tgccgcagct tctatttttc gaaacgtatt
    52681 tactgcttga aatagtagta caataaaaat aaagaggtga caattgtgat tacaaaacca
    52741 gataagaaca aaacacgtca aaagagacat cgtcgtgtac gtaacaatat ctctggtact
    52801 gctgagcgcc cacgcttgaa cgtttttcgt tctaacaaaa acatctacgc tcaaattatt
    52861 gatgacgtag cgggtgtaac gctagcaagt gcctctacct tggataaaga aatttcaggt
    52921 ggaacaaaaa cagaagcagc acaagctgtc ggtaaactag ttgctgaacg tgcagctgaa
    52981 aaaggcatta aagtagtagt ctttgaccgt ggtggatacc tttaccatgg ccgtgtgcaa
    53041 gctttagctg aagctgctcg cgaaaatgga ctagaatttt agaagaagga ggaataccat
    53101 tcatggttta tatcgatcca aaacatttgg aattagaaga ccgcgttgtt gcaattaacc
    53161 gtgtaacaaa agttgttaaa ggtggacgtc gtctacgttt tgctgcttta gttgttgtcg
    53221 gtgacaaaaa cggacacgta gggtttggta caggtaaagc tcaagaagtt cctgaagcaa
    53281 tccgtaaagc aattgaagat gcgaagaaaa acttagttga agtacctatg gttggttcaa
    53341 caatcccaca cgaagtaatc ggtgctttta gtggtggtag aatcctaatg aaacctgctg
    53401 tagaaggttc tggggttgct gctggtggac cagttcgtgc cgtattagaa ttagctgggg
    53461 tagcagatat cacttctaaa tctttaggct caaatacacc aatcaacgtt gttcgcgcaa
    53521 cagttgaagg tttgaaacaa ttgaaacgtg cagaagaagt tgcagaactt cgcggcaaat
    53581 cagttgaaga attaatcgga taaggaggac aacaataatg gctgaattaa aagttacttt
    53641 aaaacgcagt attatcggac gtcctcaaaa ccaacgcgat acagttaaag cgttaggtct
    53701 tacaaagatt aacagttcag tggttaagcc ttctaatgaa gcaattaaag gcatgatcaa
    53761 tactgtttct cacctagtgg acgttgaaga aatttaattt agaaaaatca taactagaac
    53821 attaaggagg tgccaaacct atgaaacttc atgaattaaa acctgctgaa ggttcacgcc
    53881 aagtacgtaa ccgtgttggt cgtggtactt catctggtaa cggaaaaact gccggacgcg
    53941 gacaaaaagg acaaaaagct cgttcaggcg gcggtgtgcg tttaggattt gaagggggac
    54001 aaacaccatt gttccgtcgt ttaccaaaac gaggattcac aaacgtgaac cgtaaagact
    54061 atgcagtcat taatcttgat gtattgaacc gctttgaaga cggagctgaa gtaactcctg
    54121 ttgctttagt tgaagctgga atcgtgaaaa acgaaaaagc tggaatcaaa gtattagcta
    54181 atggggaact aaacaagaaa ttaactgtga aagcagcaaa attctctaaa gcagctcaag
    54241 aagcaattga agcggctggt ggatcaatcg aggtgatcta atgtttagac tattaaaaga
    54301 tgcttttaaa gtaaaagaca ttagatcgaa aatcctattt actgtatttg tgttgtttgt
    54361 atttcgccta ggtgcacata ttactgtacc aggcgtaaat gctgcttcat tgcaaaacct
    54421 ttcttctttg ccatttttca acatgttgaa cttggtaagt ggtagtgcga tgcaaaactt
    54481 ttccattttc tcaatggggg tttcaccata cattactgct tctatcgtca ttcagcttct
    54541 tcaaatggac atcgtgcctc gatttgttga atggtcgaaa caaggggaag ttggtcgtaa
    54601 aaaactgaat caagcgactc gatatctgac attagtattg gcatttatcc aatctgtcgg
    54661 tatcactgct ggattcaatc aatacgctca attaggtttc gtgaataatc ctaacgtagc
    54721 aacttacgta acgatcggtt tgattctaac agccggtacg atgtttgtta cttggctagg
    54781 agaacagatc acagaaaaag gtatcggaaa tggcgtatca atgatcattt ttgcaggtat
    54841 catttctaga ttgcctgaaa gtatcagaga aatttatgaa gattacttta taaatattga
    54901 tccttcagac atatggaaat ctgctatttt tgtggccatt ttactagtag cggtcttgtt
    54961 gatcgtgaca ttcgtaacat ttttccaaca agctgaacgc aagatcccga tccaatatac
    55021 gaaacgcgta gctggcgcgc ctacaagcag ctatctgccg ttgaaagtaa atgcagctgg
    55081 agttattcca gttatctttg ctagttcgtt tattgctacg ccaaatgctg ttttacaagc
    55141 attgagcggt agattcggtt ctgaaaactg gtacaaagtg atgatggaga tctttaacta
    55201 taatacagca cctggtgcta cgatttatac gattctgatc gttgccttca ctttcttcta
    55261 cgcctttgtt caagtaaacc ctgagaaatt agcggaaaac ttgcaaaagc aaggaagtta
    55321 tataccaagc gtacgccctg gtaaggggac tgaagagtat gtctcaagat tactgatgcg
    55381 tttaagtaca gttggtgcag tcttccttgg tttagtggca ttgcttccaa tcattgctca
    55441 aatggtttgg gatcttccac aatcaatcgg attaggcggt acaagcttac tgatcgttat
    55501 cggtgtagct ttagaaactg cgaaacagtt agaaggctta atgctgaaac gtaaatatgt
    55561 tggattcatt gagtaagaaa gcgtgttgag gtttcccctc aacacacgtt ctcacacatt
    55621 tattaggagg gaaaacaatg aacctcattt taatggggct gccaggcgca ggtaaaggaa
    55681 cacaagctga aaaaatcatt gatgcttatg gtattccgca catctcaaca ggagatatgt
    55741 tccgcgcagc gatgcaaaac gaaacagctc ttggcctgga agcaaagtct tatatggata
    55801 aaggtgcatt agttcctgat gaagtaacaa atggaatcgt gaaagagcga ctagctgaac
    55861 cagatacaga gaaaggcttc ttattagatg gctttccacg tacgctagat caagcaaaag
    55921 ctctggacgc aatgctaaaa gatttgaata aaaaaattga tgctgtcatc gatatccatg
    55981 ttggtgaaga aatcttggtc gaacgtctag ccggccgatt tatctgcagc aattgtggag
    56041 caacttacca taaaattttc aaccctacaa aagttgaaga cacatgtgat cgttgcggtg
    56101 ggcatgaatt ctatcaaaga gaagatgata aacctgagac ggttaaaaat cgtctggcta
    56161 tcaacatcaa aaatagtgaa ccaatcttgg cttattataa agaacaaggt ttgctaaaca
    56221 ctattgatgg tgctcgtgaa atcgatgctg tatttgcaga tgtacaaaaa atcattgaaa
    56281 aatagcacga ttgcccgtag ccgacttgca ttatgcagtt actcttgtca agttcaataa
    56341 attatgatag aatatgtcag tccgacttct agagaatcct ctagatgatc cattttgaga
    56401 attttgaggt gggaactgca gtttccgcca ttttatcgtg tgaaaatgcg aaacaagtac
    56461 aaggaggtac tgtgcgtggc aaaagaagat atgattgaag tcgaaggtac agtcgtcgaa
    56521 actttgccga atgcaatgtt taaagttgaa ctagaaaacg gacaccaagt tcttgctact
    56581 gtttcaggta aaattcgtat gcattacatc cgtatcttac ctggtgacaa agtaacggtt
    56641 gaattgtctc catacgatct taaccgtggc cgtattactt atcgctttaa ataattgtac
    56701 tccgtaaaac tacaggaggt attatcatga aagtaagacc atcagtaaaa ccaatgtgcg
    56761 aacattgtaa agtaattcgt cgtaaaggac gcgttatggt gatttgccca gcaaatccaa
    56821 aacataaaca acgtcaagga taattggagg tgctataaat atggctcgta ttgcaggagt
    56881 agatattcct cgtgataaac gtgtagtagt ttcacttact tatatctatg gtattggtaa
    56941 cactactgct aaaaagatct tagctgatgc tggtgtatct gaagatgttc gcgttcgtga
    57001 attaacgaat gaacaaacag atgctatccg tgcagaagta gataaattaa aagttgaagg
    57061 ggatcttcgt cgtgaagtga acttgaacat caaacgtttg atggaaatcg gttcttaccg
    57121 tggaatccgt catcgccgtg gattgcctgt tcgtggacaa aacacgaaaa acaatgcacg
    57181 tactcgtaaa ggcccagctc gcgctatcgc tggcaagaaa aaataattct taagtgaagg
    57241 aggttaaaac ttcatggcag caaaaaaagt gaatcgtaaa cgccgtgtga agaagaatat
    57301 agaagcaggt attgcacata tccattctac attcaataac actatcatca tgatcactga
    57361 tactcacgga aatgcattag cgtggtcatc agctggttca ttaggtttca aaggaagcaa
    57421 aaaatcaact ccttttgccg ctcaaatggc agcagaaact gctacaaaag cagcaatgga
    57481 acacggatta aagactgttg aagtaacagt taaaggacct ggttctggac gtgaagcagc
    57541 aattcgttca ttacaagcta caggtttaga agtgactgca attcgtgacg tgactccagt
    57601 tcctcataat ggtgcccgcc ctccaaaacg ccgtcgtgtt taatgagtgc cgctcatttt
    57661 gagttttatc agtaacgtca ttgaacaaga cacttttcgt tttgaaaggg gtaaagataa
    57721 gaatgattga gttcgaaaaa ccaagaatcg caaaaattga tgaagaaaaa gattatggca
    57781 agttcatcgt tgaacctctt gaaagagggt atgggactac tttagggaat tccctacgtc
    57841 gtattttatt atcttctttg ccaggtgctg ccatcactaa tattcaaatc gatggtgtac
    57901 tgcatgaatt ctctaccatc aaaggtgtta gagaagacgt cactcaaatc atcttgaaca
    57961 ttaaaggctt agcgctgaaa atgtatggcc aagaagaaaa aacccttgaa atcgatatta
    58021 ccggacctgc tacagtaact gctggcgata ttatcgttga tagtgatgta gaaattctta
    58081 acaaagatat gtacatctgt agtgtctctg aaggagctac gttccatgct cgcttaacag
    58141 tgaaacctgg acgtggttat gttcaagcag atgaaaataa aaaagaagat atgccaattg
    58201 gcgttcttcc agtcgattca atctacacac ctgttcgtcg tgtgaactat caagttgaga
    58261 acacacgtgt tggacaccgt gaagattttg ataaattgac gatggagatt tggacagatg
    58321 gttcaattga accgttggaa gcaatgagtt tgtctgcgaa aatcatgact gaacatttgg
    58381 atatttttgt gaacttaact gatgaagcaa aaaatgctga aatcatggtc gaaaaagaag
    58441 aaacacaaaa agaaaaaatg ttggaaatga cgatcgaaga gttagacttg tctgttcgct
    58501 cttacaattg tttgaaacgt gcaggaatca atactgtaca agaacttaca aataaatctg
    58561 agcctgaaat gatcaaagtc cgtaacttag gacgtaaatc attagaagaa gttaaagcaa
    58621 aattgcacga cttaggttta ggtttacgta aagaagatta aaacctttta cgaaggaggg
    58681 aaaccaacgt gagttatcgt aaactaggac gcacatctag ccaacgtaaa gcgatgttgc
    58741 gtgatttaac aactgattta ttaatcaacg aacgtattgt gactactgaa gctcgtgcga
    58801 aagaagttcg ctcaactgca gaaaaaatga tcactttagg taaacgcgga gatttgcatg
    58861 cacgtcgtca agctgcggct ttcgtacgta atgaagttgc cagcgtgcgt gaagaaaatg
    58921 aggacatcgt cattgaatca gctttacaaa aactgttcaa cgatattgca cctcgttacg
    58981 cagaacgtca aggcggatac acacgcattt tgaagacaga accaagacgc ggtgatggtg
    59041 caccaatggt tgtcttagaa cttgtctaaa atcacactaa taacatcact ttatagatga
    59101 ttcttttaga gtgttatgat gttggaagat atttttccga gtctagctca gcgctgctcc
    59161 tcaagcgaat atcgcttggg gagtaagcac tcatcataaa gtgttttttt ataccttcaa
    59221 ttacctgtca tgacagatat gtttgaaggc ataaaaaaac attttaagcg agaaataatt
    59281 gaaaattttg tctttttttg atagtgttag taggaacttt aggatgaaga aggagtaatc
    59341 atggagccaa ttattgaatt agaaaagata aattataaat accagccaga tgatcttcgc
    59401 cccgcattga aagatgtctc ctttacaatt gataaaggtg agtggatcgc tattattgga
    59461 cacaatggtt caggaaaatc gacacttgcc aaaacgatca atggattgct tctgccagaa
    59521 tcagggatcg tgaaagtggg aaatcaaata ttggatgaag aaaatatttg gacgatccga
    59581 cagatggttg gaatggtttt tcaaaatcca gacaatcagt ttgttggttc gacagtagaa
    59641 gatgacgttg cttttggtct tgaaaatcaa gggattccca gagaagaaat gctagtgcgt
    59701 gtgaaagatg cacttgagaa agttagaatg gctgagtttg cttcacgcga gcctgctcgt
    59761 ttatcaggag ggcaaaaaca acgtgttgcc attgccggcg tggttgcctt acgacctgat
    59821 atcattattt tagatgaagc aaccagtatg ctagatccag aaggtcgtga agaagtgatc
    59881 tctacgatca agaagatcaa agaagaaagt caattgaccg ttatatctat cactcatgat
    59941 attgatgaag cagctaatgc caatcggata ctagtgatga gacaaggcga acttgtccgt
    60001 gaaggtacac caaaagaaat tttttctgct ggtcctgaac tgatcgactt aggtctagat
    60061 ctaccatttc ctgaaaaact gaagagcgca ctgaaagaac gtggggttga tgtgcccagt
    60121 gaatatatga cagaagaaag gatggtggat tggttatgga catccgtttt gaacaagtag
    60181 acttcactta tcagccgaat acaccatttg aacaaagagc cttatttgac atcaatatga
    60241 cgatcaaaga aaacagttat actgcattag tagggcatac cggaagcggg aaatcaacct
    60301 tacttcagca tttgaatgcg cttgttaagc caacaagcgg tacagtccat attggagaac
    60361 gagatattca gccggatacg gataataaga atttaaagcc catccgaaaa aaagttggca
    60421 tcgtctttca gtttccagaa gcacagctat tcgaagaaac ggtagcaaaa gacattgctt
    60481 tcggtcctaa aaactttggt gtcagcgaag aagaagcact agtcctagca aaagaaacat
    60541 tagaacaagt tgggctggat gaaagctatt tggaacgttc gccatttgaa ctttcaggag
    60601 ggcaaatgcg tagagtagca atcgctggtg tgcttgccat gaggccggaa gtacttgtat
    60661 tggatgaacc aacggcagga cttgatcccc agggtagaaa agaaatgatg gagatgtttt
    60721 ggcgtcttca taaggaacag cagatcacta ttgtattagt tacgcattta atggatgatg
    60781 tagccaattt tgcagattat gtctatgtgt tggaaaaggg acgaatcgtt aatagcgggg
    60841 agccgcaaga ggtctttcaa aacattgaat ggctaaaaga aaaacaacta ggcgtaccta
    60901 ctgccaccga gtttgcagaa gaattaatgg ctaaagggat gaactttgct accttgcctt
    60961 tgacagctga agaattagca gacgctatcg tccattatgc tggaggaaat gcccatgatg
    61021 aataaattga tatttggtcg ttatatgcct ggagattcct tgatccatcg attggatccc
    61081 cgagctaaat tattagccag tttttatttt atcggaatca tttttttagc aaataattgg
    61141 gaaacgtacc ttttgttggc atttttcaca ttactttctg tcttcttgtc aaaagtagat
    61201 ttgaaatttt ttatccgagg cattcgccca ttgatctggc taatcctctt cactgtagct
    61261 ttgcaggtct tgtttacaag tggcggagaa acttattgga gttggggtgt tttccatatc
    61321 actgaatttg gtgtgatgaa cggcctcttt attttctgtc gattcgtgtt gatcattttt
    61381 atgtcgactc tactcacgct tactacaccg cctttggaat tatcggatgc gattgagtac
    61441 ttgcttcgtc cattgaaagc cgtacggttc ccagtccacg aaatttcatt gatgctgtcg
    61501 attgctcttc gttttgtgcc tacattgatg gacgaaacag aaaagatcat gaacgctcag
    61561 cgcgctcgcg gtgttgattt tggtgaagga aacctagttc agaaaatgaa agcagtcatt
    61621 cctttgctga ttcctttatt tgtcagcagc ttcaaccgtg cggaagatct tgcgactgct
    61681 atggaagcaa gaggctacaa aggtggggaa ggaagaacga aatatcgtgt attgcattgg
    61741 cataatagag acacgatggt tatcattgct tttgtattat taactgtgct actgatcttt
    61801 ttgagaggat aaacgttcag tgggccgcta tctattcttt tcttgctgat ctgtttgcaa
    61861 gaaaggatgc gagcagtgta tgacaagaaa tattagggtc tgtggcagac taaggtcaca
    61921 ggcctctttc ttttatctga aaagaaagaa cgaaaaaatt ttataaaaaa atcattattc
    61981 cagataacct tttaggaaca aaggagagaa aaacatggta cgttacaaag caatcattgc
    62041 atacgacgga acaaatttta atggattcca aaaacagcca aatgggcgta ctgttcaaga
    62101 agaagtagaa aaaacattac aaaaaatggc aaatggaaaa gaaatcacgg tctttggttc
    62161 gggaaggaca gatgccggag tacatgcgat tgggcaagta atccattttg attatccaga
    62221 ggagcgtccg ttagaacgaa tgcgtttcgc gctagatacc cagtcaccag aggatattgc
    62281 tgtaagacaa gtagaaattg tttcagaaga cttccacgca agatatttgg tcaaagaaaa
    62341 gacgtatcaa tttcgagtgg atatagggaa accacgcagt ccttttcgac gccattatgc
    62401 aagttatttt ccttaccctc ttgatttgga aaaaattcag cgggcgcttc ctgatttatt
    62461 agggactcac gatttcacct ctttttgtgc atcaggaagc tcgatagagg ataaagtacg
    62521 tacgatctac gaggctaaga tggaggtaaa tgaaacaaaa gacgaattgt tgtttacatt
    62581 taggggaaat ggcttcttgt ataagatgat acggatctta gtaggaacgc ttttgaaaat
    62641 tggcaatggc cgattgcctg aagatagtat cccagatatt attgcgaaaa aagatcgtaa
    62701 tgcagcagga cctacagcac atcctgaagg actttatttg tatgaagtga aatatgaata
    62761 agaggttgtg acagaagtgg tcagcttcaa gaaataagaa ggaatttacg aaaattactt
    62821 ctcaaaattt tgcaaaattt cggcttattt tcgaaggagc tacttctgga acaccgtgaa
    62881 tcagaggttg tgaaaaagct gccctgcatc aagtaataag aacaaccaaa caaaaatagc
    62941 tcgtcatatt tttcgtttgg ttgggcttat taccgcagat gcaagctttt gaacaccgtt
    63001 taaggaagag gttgtgaaat cagcgttttg acctgagtat tagagaaaca aacggaaaaa
    63061 tagttcctca tattttgccg tttgttgagc taataccgaa ggtcagctga ttgaacaccg
    63121 tttaagaaag aggtcgtgag cctgtcattt aactctgagt cacaagtaac aatttcaaaa
    63181 aacagcttct catctttgat gaatatcgtg acttgtggac gaggcgttga taagtgaatc
    63241 atctttttgt tacctatttt ttctgtaacc aaaaaacgat ggaacgttgt tttgattgcc
    63301 cttaatgagg acagtcggaa caggtttgtc atttttatat ttaaatggca caaatttttc
    63361 taattatttg tcatttagcg ctgaaaattt ttgctattta tctaaaaaag tgataactac
    63421 ttaagatgaa gcagaatatt tacgccatac ggcatacaac cgcgaaaaat ataaaaaaaa
    63481 gaaaacgatt gaacgcgttt ttgcagtcgc aaaggaaaag catggaatgc gctacatcaa
    63541 gtatcgagac ttggaaaaca atcaggtgta tacgctgatt gtttttgctg caatgaatct
    63601 gaaaaagttg tccacttggc agttggaaca tatgtcttca tatcttttat tatacaaaaa
    63661 tagcaaaagc accagtctac actcttagta aagaggaaac tgatcctttt gtctacattc
    63721 ttaaagtact taaactaagt actttatttt actctttagg attgatacag tagcatctat
    63781 ccctttatta ataatctttt atttttttaa ataaagatgt tgtctccatc ttcaggcact
    63841 aaaacttttt cggaaattcc tttttcttta ttgaaagact ttaattcttc tcttgacagt
    63901 ccccaatggt ttacagcttc catatgaacg gcaataattg tggaatctgg tattgcttta
    63961 tgcaattcat ataaatcgtc tttccccata ataagagatt ctccaactaa aaaatgatta
    64021 tctccagcat ttgctactat gatttctgga ttatactgat caatagtttg tttaacagct
    64081 tcataccaaa ctgtatctcc tgtaaagtat agtgtcttct cagtcgaatg tttgaaaaca
    64141 ataccgcaaa cattacctac ataattcaag atttctcctc tgccatgttt gccttttgtt
    64201 ttaaccaatt gtatagattc aaaaactgtg tcttctcgta gtacctccac atttttaaaa
    64261 ccatatagtc gaatttcatt cgcatcattt tcatcttgca caaataattt tatttcttta
    64321 ggtaggacct ctttcgctat atcgtcccaa tgatctagat gtaaatgtgt tacaataaca
    64381 gcatcaatac cgttgataat atcttcgact ggcattggca aatcaactag aggattcatt
    64441 tgatcttttc ttggtgatgg aaaaggacct ttcgaaataa atggtggaag tgttcctttt
    64501 tccgctaaca ttggatcaat taaaaatttt ttacctccat agtctaagat agctgttgca
    64561 ttacgaatgt gatgtatatt cataaacgtt gtctcctttt tgttgatatg aaatattttt
    64621 agtataattc aattccatac aataaataaa ccgaacaaaa aaagtctttt actattttta
    64681 cttaatttat gaaaggttgt ttaccatgtt agaccaaaca gatataaata tcattgagga
    64741 actatcaaaa aatagtcgaa tcacaatgaa agaacttgga gaaaaagtac atttgactgg
    64801 acccgctgtc tcggcgagag tgacaaaact agaggaaagt ggagttattg aaaattatac
    64861 agtaaaatta aatatggaaa agctagggtt ttcgattcac gcttttttaa ttataattac
    64921 gcaaaattta aatcataaac cctatttatc atttattaaa aatcatgaaa aattcttgat
    64981 tagaaattat aagattagtg gagggggctg ttatcttttg gaatgtagat ttacttcaaa
    65041 aaaatcaatg aacagctttt tggaacagct taatgaatat gcgaattata aattatctat
    65101 tgttatagat taataataaa actagcagat ggtaaaaata ctaatatgcg agacacacat
    65161 tcaaccataa ctatataact tatcaattta aaactaaact gatggaaaca agtaaggcaa
    65221 aaacatttat attttgccct acttattttt ttaattaaat tcattgatga ttcatattta
    65281 gaaaattcta tgaaggccaa atgagtatcc tgtcactttt ttagataaat agcaaaaatt
    65341 ttcagcgtta aatgacaaat aattagaaat atttgtgcca tttaaatata aaaatgacac
    65401 caagtatatc atgaacgcac aaaaagacca acagggtata ccctgttggt ctaaataa
//
LOCUS       DACGEU010000004        63818 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.004, whole genome shotgun sequence.
ACCESSION   DACGEU010000004 DACGEU010000000
VERSION     DACGEU010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 63818)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 63818)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..63818
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.004"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            125..1168
                     /locus_tag="IXR40_000240"
     CDS             125..1168
                     /locus_tag="IXR40_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HAQ4360118.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(1230..1694)
                     /locus_tag="IXR40_000241"
     CDS             complement(1230..1694)
                     /locus_tag="IXR40_000241"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HAQ4360119.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            1940..2887
                     /locus_tag="IXR40_000242"
     CDS             1940..2887
                     /locus_tag="IXR40_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAQ4360120.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            complement(3098..5170)
                     /locus_tag="IXR40_000243"
     CDS             complement(3098..5170)
                     /locus_tag="IXR40_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAQ4360121.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(5103..5480)
                     /locus_tag="IXR40_000244"
     CDS             complement(5103..5480)
                     /locus_tag="IXR40_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HAQ4360122.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            complement(5609..6169)
                     /locus_tag="IXR40_000245"
     CDS             complement(5609..6169)
                     /locus_tag="IXR40_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAQ4360123.1"
                     /translation="MKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDIKAPSLY
                     NHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSNQAVYEL
                     LISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYLSLRFLG
                     YFTKEPTIDPEDSYFWMINNFIATLP"
     gene            6319..7611
                     /locus_tag="IXR40_000246"
     CDS             6319..7611
                     /locus_tag="IXR40_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAQ4360124.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            complement(7671..8789)
                     /locus_tag="IXR40_000247"
     CDS             complement(7671..8789)
                     /locus_tag="IXR40_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HAQ4360125.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(8803..10224)
                     /gene="arcD"
                     /locus_tag="IXR40_000248"
     CDS             complement(8803..10224)
                     /gene="arcD"
                     /locus_tag="IXR40_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HAQ4360126.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            complement(10470..11591)
                     /gene="mnmA"
                     /locus_tag="IXR40_000249"
     CDS             complement(10470..11591)
                     /gene="mnmA"
                     /locus_tag="IXR40_000249"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HAQ4360127.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            11995..12594
                     /locus_tag="IXR40_000250"
     CDS             11995..12594
                     /locus_tag="IXR40_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphatase"
                     /protein_id="HAQ4360128.1"
                     /translation="MNYFISDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            complement(12732..14018)
                     /gene="efmA"
                     /locus_tag="IXR40_000251"
     CDS             complement(12732..14018)
                     /gene="efmA"
                     /locus_tag="IXR40_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HAQ4360129.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(14289..14633)
                     /locus_tag="IXR40_000252"
     CDS             complement(14289..14633)
                     /locus_tag="IXR40_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HAQ4360130.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            complement(14770..15906)
                     /locus_tag="IXR40_000253"
     CDS             complement(14770..15906)
                     /locus_tag="IXR40_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HAQ4360131.1"
                     /translation="MKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGRHAH
                     EKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIEHPA
                     VLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLMPIK
                     EIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKRDGV
                     NIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLILDTL
                     EANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNIEPS
                     HVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            complement(16095..17069)
                     /locus_tag="IXR40_000254"
     CDS             complement(16095..17069)
                     /locus_tag="IXR40_000254"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HAQ4360132.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            complement(17149..18024)
                     /locus_tag="IXR40_000255"
     CDS             complement(17149..18024)
                     /locus_tag="IXR40_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HAQ4360133.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            18154..20061
                     /locus_tag="IXR40_000256"
     CDS             18154..20061
                     /locus_tag="IXR40_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M13 family peptidase"
                     /protein_id="HAQ4360134.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            complement(20602..23880)
                     /locus_tag="IXR40_000257"
     CDS             complement(20602..23880)
                     /locus_tag="IXR40_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1565 domain-containing protein"
                     /protein_id="HAQ4360135.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
     gene            complement(24151..24696)
                     /locus_tag="IXR40_000258"
     CDS             complement(24151..24696)
                     /locus_tag="IXR40_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAQ4360136.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDSVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(24708..25400)
                     /locus_tag="IXR40_000259"
     CDS             complement(24708..25400)
                     /locus_tag="IXR40_000259"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HAQ4360137.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(25419..25703)
                     /locus_tag="IXR40_000260"
     CDS             complement(25419..25703)
                     /locus_tag="IXR40_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360138.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(25716..26279)
                     /locus_tag="IXR40_000261"
     CDS             complement(25716..26279)
                     /locus_tag="IXR40_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HAQ4360139.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            26507..27169
                     /locus_tag="IXR40_000262"
     CDS             26507..27169
                     /locus_tag="IXR40_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     protein"
                     /protein_id="HAQ4360140.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            27293..28489
                     /locus_tag="IXR40_000263"
     CDS             27293..28489
                     /locus_tag="IXR40_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HAQ4360141.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(28590..29966)
                     /locus_tag="IXR40_000264"
     CDS             complement(28590..29966)
                     /locus_tag="IXR40_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAQ4360142.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(30003..30869)
                     /locus_tag="IXR40_000265"
     CDS             complement(30003..30869)
                     /locus_tag="IXR40_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose transporter GlcU"
                     /protein_id="HAQ4360143.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(30958..31983)
                     /locus_tag="IXR40_000266"
     CDS             complement(30958..31983)
                     /locus_tag="IXR40_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAQ4360144.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(32001..32675)
                     /locus_tag="IXR40_000267"
     CDS             complement(32001..32675)
                     /locus_tag="IXR40_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4360145.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(32859..33752)
                     /locus_tag="IXR40_000268"
     CDS             complement(32859..33752)
                     /locus_tag="IXR40_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAQ4360146.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(33826..35523)
                     /locus_tag="IXR40_000269"
     CDS             complement(33826..35523)
                     /locus_tag="IXR40_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HAQ4360147.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(35516..36829)
                     /locus_tag="IXR40_000270"
     CDS             complement(35516..36829)
                     /locus_tag="IXR40_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAQ4360148.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPVNDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(36829..40866)
                     /locus_tag="IXR40_000271"
     CDS             complement(36829..40866)
                     /locus_tag="IXR40_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HAQ4360149.1"
                     /translation="MVVDERIDNQELQENETDTEDSAEIQRSEENEMEKLDEPIVPSG
                     QALQRIQRQLFNGILERLGPTATQDPYEYIYPSGEVENEQHRYPKFTTNDYTKVLGNW
                     TQSNERYQGDKGSPYDGENLIDDSDYTNGGANWRNYDYATNNGSTAGEEDRNVPAQTV
                     QLWGNERNFENSYLDYNGAYIKKWVEPVLPSSTASDLHPEDATTLYNVYLDVIGGEKK
                     EISPIDIVFVLDKSASMSELTAGTNSQTKNAALIEAVNEMSKDLLSDPSLDIRIGMVN
                     FYHNSTAINNHEQISSDIFPLTNDINRLTGSENTALNRTPIGGTPLTLGLKNGYETLY
                     KDNGGENRNPEKILIVVGDGTPTFSYAPIQSSYRTSTNGAWSNWTVMEDKIAEDNDVL
                     FRNFEEFSGNTSNAGFTHPVTYASDFNRPEDEVNVHYRYGEVKEGDNKATHWVGDGSS
                     NNNTNGSPTSQEKSSAINTVAYHHWLKNKYQENPPSIFSIGLGIDGNVSGRQRLDAIG
                     RNVLKNIADLEEDGVTPRYYNANNKNDIVTALEDISSTFKRTIQQATLYDETGFNVSP
                     FGAGRSADIQFYHLDPGENGMKYQEPEIWDEERHGQAPPEVVATPTTYVGRENQAYKF
                     SPISLGEGEMVRIKYQVKLDAGAQDGNFCTVNNMAYIQNLEDYENDITTGRMYFPSSS
                     IRYEHKGRNFQVSKKGQNGEPLAGVEFALYDQNPESGEAEPIETSKTTTDGIAIFETK
                     MPILGDETGAVSDIFWIREIAGPPRYQLVDETYQFQIKKYAANEDEMLGHYELVDEYT
                     SGSRVGGPEGKDPNSYYEGEYHKLSVVQEPNIEGTEYDELYVKLEMRNEFKPIHMNIN
                     KLIEGSNMPINGAEFELYETDGNGLEIGYPVAKGLSGVNEVEEEKGRLTFYSVDEDGK
                     YVIVDGEKVIHPIGEPDSFVYKDSEETTNYAEYKIIESQNPEGFKEPDENDTWILRLY
                     DNAIGTIQLKQTGEENWQYLTYTTDEEDRLWVAFTAYNTFDYREIRVRKLDHEGHTLD
                     GAGFDIRKVGDSSFPLYRAYTGNPLEPEESKRLPGIGYFYSRAVGVEKYVDLNYDQPL
                     HLSIGEYEVSESVAPNGYRLSDQVFQFALNEEGKFIIEDTVIEDETAPLPEGYEIIDG
                     VLQVTLEDELAPIDLELLKIDSMNSRRLEGAEFSIEKQNSAGEYEIIEGGLAPDPNDS
                     SLFNASDLLEGVYRIKEVKSPDSYRKLPGYFILEISYREEPDIENDRVVPGKEAGTLK
                     VEISYYPNEEAETPDLQQELEYELLETNRIRLQLSVGNDPENPLPATGGSGRLFYILL
                     AAFFMALAGAAYGLFVRQSKKEGAR"
     gene            complement(40879..41337)
                     /locus_tag="IXR40_000272"
     CDS             complement(40879..41337)
                     /locus_tag="IXR40_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAQ4360150.1"
                     /translation="MKGLKLKLLQLVTVSLLFGPYFQSVYHMTTLDVAAESTETKEDE
                     VFLDEDYAKIEGKYIEKEETLEWHLAFEKKESANEGRIRLAIDAAAAGIGTVKNVRGT
                     GLSSYDEDGEDLKVETIDGQEWYVGKVYSKEAETGTLIFETEKIPDVNEG"
     gene            complement(41635..42153)
                     /locus_tag="IXR40_000273"
     CDS             complement(41635..42153)
                     /locus_tag="IXR40_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HAQ4360151.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(42155..42772)
                     /locus_tag="IXR40_000274"
     CDS             complement(42155..42772)
                     /locus_tag="IXR40_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HAQ4360152.1"
                     /translation="MMNRSIGKKANDYFLEIIEWIPRLIHLQLLWFLCVLPVFTLGTA
                     SRTVLYMIYHYKKNEEKKLGSLFWKKFRENFSLYGKQDSLASVYFLLLLIDYQIFRYW
                     GGGIGYTLMYTTLFLLLLSALLFSYKILLQLEQKEASWITAFFLFFNDFKSALFYLAG
                     TLILLVAFWFAGPIYFALLGFSFLFYFQVLLFIHRTQEKVLKKEE"
     gene            complement(42769..43623)
                     /locus_tag="IXR40_000275"
     CDS             complement(42769..43623)
                     /locus_tag="IXR40_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAQ4360153.1"
                     /translation="MMDYFKKTSVNRQTKKILSYVLMTVIGIILIIPLLWMVFTSLKP
                     MEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFIAYG
                     FAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGNAFN
                     IFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWNDFL
                     GPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFIEGM
                     DLTGGSKG"
     gene            complement(43620..44531)
                     /locus_tag="IXR40_000276"
     CDS             complement(43620..44531)
                     /locus_tag="IXR40_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAQ4360154.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAMSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(44572..45906)
                     /locus_tag="IXR40_000277"
     CDS             complement(44572..45906)
                     /locus_tag="IXR40_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAQ4360155.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKLFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            46114..46944
                     /locus_tag="IXR40_000278"
     CDS             46114..46944
                     /locus_tag="IXR40_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HAQ4360156.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(47188..47437)
                     /locus_tag="IXR40_000279"
                     /pseudo
     CDS             complement(47188..47437)
                     /locus_tag="IXR40_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(47628..47822)
                     /locus_tag="IXR40_000280"
     CDS             complement(47628..47822)
                     /locus_tag="IXR40_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360157.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            complement(48327..48512)
                     /locus_tag="IXR40_000281"
     CDS             complement(48327..48512)
                     /locus_tag="IXR40_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360158.1"
                     /translation="MSKNSKGFLTILLAFIGYMLVGLLKSYSNELLNFSTFINDTLVP
                     SLFFIVFFAVGYFIIKI"
     gene            complement(49362..49703)
                     /locus_tag="IXR40_000282"
     CDS             complement(49362..49703)
                     /locus_tag="IXR40_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAQ4360159.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(49703..49933)
                     /locus_tag="IXR40_000283"
     CDS             complement(49703..49933)
                     /locus_tag="IXR40_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016178973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAQ4360160.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            50220..50558
                     /locus_tag="IXR40_000284"
     CDS             50220..50558
                     /locus_tag="IXR40_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360161.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(50763..51002)
                     /locus_tag="IXR40_000285"
     CDS             complement(50763..51002)
                     /locus_tag="IXR40_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase"
                     /protein_id="HAQ4360162.1"
                     /translation="MFSNKEKIVYIGGFYRSHQDEKMAESIIMTTEPNRTVAPIHDRM
                     PLVLTEEQIEPWVTDISFARKIITQQMPELVMEKV"
     gene            complement(50978..51325)
                     /locus_tag="IXR40_000286"
     CDS             complement(50978..51325)
                     /locus_tag="IXR40_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF159 family protein"
                     /protein_id="HAQ4360163.1"
                     /translation="MCGRYFFDLESELLQNYYREAQTKQPKQAAELAAGEVFPSNLVV
                     TLRKEEENILTPEIMKWGFTGFKKGQLMINARAETVEEKKTFHQPFLQNRCVFPMSGM
                     KKKTNLCFQIRKK"
     gene            complement(52057..52638)
                     /locus_tag="IXR40_000287"
     CDS             complement(52057..52638)
                     /locus_tag="IXR40_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAQ4360164.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(52821..53447)
                     /locus_tag="IXR40_000288"
     CDS             complement(52821..53447)
                     /locus_tag="IXR40_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAQ4360165.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(53469..54800)
                     /locus_tag="IXR40_000289"
     CDS             complement(53469..54800)
                     /locus_tag="IXR40_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HAQ4360166.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(54955..55356)
                     /locus_tag="IXR40_000290"
     CDS             complement(54955..55356)
                     /locus_tag="IXR40_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HAQ4360167.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(55442..55648)
                     /locus_tag="IXR40_000291"
     CDS             complement(55442..55648)
                     /locus_tag="IXR40_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360168.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(55743..57245)
                     /locus_tag="IXR40_000292"
     CDS             complement(55743..57245)
                     /locus_tag="IXR40_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HAQ4360169.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(57263..57718)
                     /gene="argR"
                     /locus_tag="IXR40_000293"
     CDS             complement(57263..57718)
                     /gene="argR"
                     /locus_tag="IXR40_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HAQ4360170.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(57816..58433)
                     /locus_tag="IXR40_000294"
     CDS             complement(57816..58433)
                     /locus_tag="IXR40_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360171.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            58654..60027
                     /locus_tag="IXR40_000295"
     CDS             58654..60027
                     /locus_tag="IXR40_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAQ4360172.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLFLSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            60102..61214
                     /locus_tag="IXR40_000296"
     CDS             60102..61214
                     /locus_tag="IXR40_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HAQ4360173.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(61286..62923)
                     /locus_tag="IXR40_000297"
     CDS             complement(61286..62923)
                     /locus_tag="IXR40_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HAQ4360174.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAAVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(63091..63699)
                     /locus_tag="IXR40_000298"
     CDS             complement(63091..63699)
                     /locus_tag="IXR40_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAQ4360175.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
BASE COUNT        18206 a        13505 c        11305 g        20802 t
ORIGIN      
        1 tattcgaaac aagaggtcgt acaagacttt tgtcacgacc tcttgttctt ttgtcaaaat
       61 actggtttag tgctactatg ttcgagtatg cttttagtat ttattgacga aaggaaccga
      121 tcaaatgaaa tcattgtcac atccaataaa atctgtaaag gattcagcgg tccgcgaaat
      181 cttacccggt ttactgcttt cttttgccat cgctgccttc agcaggcttc ttgctattta
      241 tctgccacag ttaggtggag cgactattgc tattttattg ggtattttat taggaaatac
      301 tttttttaaa cagcctgttc tagcaatcgg cacaaaattt gctgaaagca aactattaga
      361 attctctgtt tttttactag gtgcaactgt cacagctcaa acgattgctc aaattggtgt
      421 aaaaggaatt gtttttgtgt tactgcaaat gtcagtcact atcatcggtg cttacttgat
      481 tggtaaaaaa ctgcaattca gcgatacttc ttctttgatg atggctggag gaaacgctgt
      541 ttgtggttct tctgctattg cttcaatcgc cccttccatc catgcgaaag aggaagaaaa
      601 aggacagatc atcacactag tcaatctact gggtactgtg atgatgttga ctctcccttt
      661 tcttggatta cagttgtttg gtggaaatct cattgaaaaa agtgcacttt tgggtggtac
      721 actccaatct gttggtcaag tagtcgctgg ggcaagctta cttgacaatt ctgttgtcga
      781 attcgccatg ctatttaaga ttctacgtat tatgatgctc gttgttgttg tctatctgtt
      841 tgaaaaattc atgcacaaga aacaaccagc tctgtttgaa acgccaactg atacgcagaa
      901 aaaacgaaaa ttaccgcttc cttggtatgt attagggttt gtgatctttt gtttggtcaa
      961 cagcttgttt tctttacctg tagttattga ccaatcggca cattttatca gcagctggtt
     1021 tgagatcact gctttagcgg caattggtct gcgtttagac tttgcaaaat tcatgaaaga
     1081 aggtacacgc ttcttatctt atggattagc tgtcgggctt ctccaaacag tgatggcttt
     1141 actatttatt tggctgatca aagtttagaa tgaacatgaa aaaacagttg tgattctcgc
     1201 atggaacaat gtccgaatca caactgtttt taattttgca gatatccttc taacaacaac
     1261 aattggcgtt tgatttcaac cccatctatt gcgtttccca tatatcctgt cagttttcca
     1321 ttttgcccga tcactcgatg acaaggaata acgattggca atggattggt tcgatttgcc
     1381 tgcccaatcg ctcgcacagc tttcggacta tcaacagcaa cggctacttc tttatacgtt
     1441 cggatttctc cataaggaat ggtcgacaaa gctttccaga cattttgctg aaaaggcgta
     1501 cctctcttta tagataaagg aacatcaaat tcttttcttt ttcccgcaaa atattcttca
     1561 aactgttctt gtgtgcgcgt taaaattcgc tgattcgctg attcgctttc tgaaattggc
     1621 tgaaaagata cagcagtcaa tccggattca tctgcatcta accataaaaa gccgataggt
     1681 gtgtgtattt tcattttgtt tgctcctagt caatagactg gaacttcctc ctttttctct
     1741 atccaaaact acttgccaac taataaaaat tgttcttaaa agtttgataa accgaggaaa
     1801 catggtaaac taaatacgtt agtttacaaa aagaatacct gttcttttac gtaaaatcaa
     1861 attttaaagg tgttatttaa ggtttattaa attttgaatg taaaccatat ataaacatac
     1921 gattgaaagg atagaaacga tgaaagtatc aattgttgtc ccatgtttta atgaagaaaa
     1981 aactgttcct cttttttttg atgaggttga aaaattcaaa ggtgcccatg agttcgaata
     2041 tttgtttatt gacgacggat caaaagacgg tacgttagca gcaatcaaga agctagcctc
     2101 agcttatcct tatgtccgct ttgtctcatt ttccagaaat tttgggaaag aagcggctct
     2161 gtacgctgga ttgcaagctt ctacaggaga tttagtgacc gtgatggatg ttgatctgca
     2221 agatccgccc gaactgcttc ctgagatgat caaccggatc actacttctg atatcgattg
     2281 tgtcggcacc cggcgttcga ctcgtgaagg cgagcctgcg atacgcagtt tctttgcgaa
     2341 aaaattctac cagttgatca ataaaatcag cgatacagaa atggtcgatg gcgctcgtga
     2401 tttccgcttg atgactcgtc aaatggtgga tgccgtccta gaattaacag aatacaaccg
     2461 attttcaaaa ggattattta gctgggtcgg atttaaaaca gaatatattt cttatgaaaa
     2521 ccgcgaacgt gtggctggcg aaacatcttg gtccttctgg aaattattca actactcgat
     2581 tgatggtatc gtgaacttct cggatgcacc gttaacgatt gcttcattta tcggcgcttt
     2641 gtcttgtgtc ggttctggta ttgcaatttt gttcattatt ttgcgggcat tgttgtttgg
     2701 tgatcctaca tcaggatggc cttccatggt ctcgatcttc ctgttcattg gtggaatcca
     2761 attgttatgt cttggaatca tcgggaaata tattgggaaa atcttcttag aaacgaaaca
     2821 gcgtcctgtt tatatcataa gagaaacaga aaaagtgaag ccaaatgaat tgaagcctca
     2881 ccaataatat acgtcaaatg aagtaaacat ttttttaaat gaaaaaggac tgtgacaaaa
     2941 gtcttgtcac agtccttttt tccgaataaa tggtgttcca gaagtagctt cttcggaaat
     3001 aagccgaaat ttcacaaaaa tttgagaagc aattttcgta aattccttct tatttcttga
     3061 agctgaccac ttctatcaca acctctttca tatcttatta cttcttcatt gctgctttta
     3121 gtgctgctgc taatgggctt tcttctggtt cttctgcttg tgcatatttt ttcagcaagc
     3181 gtcgttcttc atgtttggtc attttcttct tctgctcttt tttatcaagc aatttttctg
     3241 tcgttccatc gtatttacaa cggaaataag caccgttttt accttcgatg atttccattt
     3301 tccggtgaca ttgcgggcat cgatgattag agacttttgg atcttttctt ctgcggtagt
     3361 tgcaatctga attggtgcag acatagattt tgccgtcacg tgtgtttttc tcgcgcagat
     3421 tggccccaca ttctgggcat ttcttttggg taatcgagaa atcttgatat tcttgtttgc
     3481 ttgatttgat ctcattcacc aagcgttttg tttctttttc gattccattc aagaaggttc
     3541 ctgcttgttt ctttcctgca gcaatagctt caaggtcttt ttcccagctt tctgtcaaat
     3601 ctggtgttac taaagaggga tttaccaata ctaataattg cttaccttta ggagatactt
     3661 gcagtccttg aggggtacgt tccatcagtt cagatttgat tagtttctcg ataatctctg
     3721 cacgcgtagc tggggttccc agactgtatt tttccatttg accaagcaag cttgcttctg
     3781 acaatggttt aggcggtgca gatagttctt ttttgatggc gaaatcggga ttgattctca
     3841 ttcctttttc ccatttgact gtttccgtct cagtttcagt ttcgcctttc catcctgctt
     3901 ggacgacacg attttgccga aaaatgaatc gttctttacc aaattcaacc gtaacttttg
     3961 tttggctgac tttatggggt tgagcaaaca gtcctaaaaa acgagagaca atcatttgat
     4021 agatttttcg ctcttcatta cttaattttt cataacgtgc tctgttttca gttggcaaaa
     4081 gtgcatggtg atcggtcact ttactgtctt ggaatacttt tgtctgttgg acgatggctc
     4141 cgtttttcaa atactgcttg acctcaggag caaagtcgct gactgcttgc aatcgttctt
     4201 tcatcgtact tttcatgtca tttgtcagat atttgctgtc tgtacgcgga taagtaacga
     4261 tcttatgggt ctcatacaaa ctttgtacaa gacttaatgt tttctttgca gaatagccat
     4321 agcgttgatt ggcttctctt tggatctctg ttaaatcata aggcaatggc gcagattccg
     4381 tttttaattt ttcttggact tctgtgacag ttcctttgct tgtactgatc aattgaacaa
     4441 gtttttgtgc ttcttcttgt gtttttaaag caaattgatt tttttgaagc attttggctt
     4501 gttcttttcc agcttgcaac gtgatcgtga aatacgtttg tggacggaac tgctcgattt
     4561 tcttttcttg gtctctcact aatgctagtg tcggtgtctg cacacggcct gctgataaat
     4621 tatccgcgta cttcacagtt aaggctctgg tcacattcaa tcctaccagc cagtccgctt
     4681 ttgcccgggc aagagcagat tcatacaatg catcatattc tttcgcaggt cttagttgct
     4741 tgaatccagt tttgattgct ttatctgttt gagaagagat ccataaccgc ttcactggtt
     4801 tattgaaatg cacatactct aagatccagc gagcaacaag ttccccttct cttccggcat
     4861 ctgtcgcaat gactgcttct gagacatctt ttcgctgagc cagctgcttg attgctttta
     4921 attgatgtcc tgttttagga agtggtttga ttcctagttt tttagggatc attggcaacg
     4981 tgtccatttg ccagctctgc cattccttat tcagatcttc cggcattttc aatcctaata
     5041 aatgaccaag ggcccaagta acgatcacct tgggtccttc ataataattt ttgtgctttt
     5101 gattagcacc aagcaccttg cttaggtctt tcgcaacgct tggtttttcc gctagaatta
     5161 gttgtttcat aaaattcctt tctgctttct actgtgatgg gctgatgatt tttcaacaac
     5221 gcaagtccct tgtattgctg taaatcatcg tcacactctt cacaccagcg ctcatctccg
     5281 tcattccaaa aggcgctgag aaagttactt tttgcattga tatattcata attttgatgg
     5341 atttcgttcc attgtttttc gtacgcttgt cgtgcttctt cgaaagactc gaatgtttct
     5401 tcttcttcaa tatcttcttc ccagtcttca aaaaaccacc aaggctcatt gtccccgaac
     5461 atggtaatta cttgatacat actcgtgctc cttctttcag cttttctaga ctcatcttag
     5521 tcacttttca agaaagttgc aagaattttc tcttataaaa gggtcattta atgaacatct
     5581 taaaattgtt acaaatgaat ctgattgttt aaggcaaagt agcgataaag ttattgatca
     5641 tccaaaaata gctgtcttct ggatcgattg ttggttcttt tgtaaagtat cctaaaaaac
     5701 gtaaggaaag ataaccgtgg atcatactac gaagttccct gcttcgatga actttttctt
     5761 ctttcgttaa ttgaaaagcc tcaaatatct gcaaaatgat ctgattcgtt tcatggattc
     5821 catctaataa aacagcttca ttggtatgcg gtacactgat cagtaactca tacactgctt
     5881 gatttgaaaa agcaaaggat cgataagttt ctgcatagat ctgcagtgct tcctgaccac
     5941 tttttcccac aagagcccgt cgcagctggt cattaagttc ctgcagaagt ttcgctgtta
     6001 gcgctgtttt gacatcacga atatttttga aatggttata cagcgaggga gccttgatat
     6061 ccaagcgttt ggctaaatgc tgaaaggtta tttgctgaac atccatctct tctgctagtt
     6121 ctcgaaagca gtcgatgatt ttctcttgag acagatttct ttttttcatt tccatgtttc
     6181 ctctcataaa ataaatcctt cactctttca gtttaccacg aaaaagaaag agaaaaaaga
     6241 gactttcatt gataaactac atattgtagt ttataataaa gagctgtaga tgaaaatttt
     6301 cagaaagaag gagtctaatt ggctgcaaga ataaaggaaa aattatttag gaaaagagaa
     6361 acttgggaac aaaacttgtt tgtcttatgg tttggaacat ttatggctgg tatcggattt
     6421 agtttagtca tgccttttat gtcactttac atagatacgt taggtaatta tagtacgtca
     6481 caattgaact tttggagcgg attgactttt tcatctactt tcttggtgac tacgcttatc
     6541 tctccttggt ggggaaaatt agccgaccaa aaaggaagaa aattgatgct gttgcgtgct
     6601 tcattaggaa tggcaatcgt catttctttg atgggttgcg tgactagtgt gtatcaatta
     6661 gtcgcattgc gtctgcttca agggattttt tctggttata tcagtaatgc cactgccctt
     6721 gtcgcaactg ggacgccaaa agaaaaaagt ggtcaagttc ttggaacctt agcaactggt
     6781 tctgttacag gaacattact tggaccgctt cttggcggga tctctgcttc agcgtttggc
     6841 tatcgcccta cctttttcat tacagggatc atcttatttt tcgtcttctt gttgagtctg
     6901 tttttcgtcc atgaaaaatt tgtcccagtg aaaaaagaaa acatggtttc tgccaaacag
     6961 attttcaaag acttgaaata tccacacgtc gtcatcggta tgttcgtcac aacgatgatc
     7021 atccaagcat ccaacaattc cattagtcca atcatcagtc tgtacattcg ccaattgctg
     7081 catggacatg ggaatgttac gttgatcagc ggaatcattg cttcgatacc tgggattgcc
     7141 actttgatag ccgctccaag atttggtcgc ttaggtgaca agattgggag tgaaagaata
     7201 cttgcgattg gtttgggttt tgcgattctg gtttatatcc caatggcatt cgtcacgaat
     7261 gtttggcaat tagctgcctt acgttttttg attggtatct ctgatgcttg tctgctccct
     7321 gctgtccaag cattgatcac aaaatattcg cctcatcaag ctgctggacg gatcttcagt
     7381 tataaccaat ctttccaagc aactggtaac gtagtagggc ctatgatcgg ctccagtgtt
     7441 tccagtgcat ttggttatcg cggcgtcttt ctttcgactt ctcttcttgt tttggtcaac
     7501 ttcttgcttg tacgacacaa tacacaagag atccatcagc aagaaactgc agaagaaaaa
     7561 gcttcaggag tctccatagc ttcagggcac tctccttctc atagacaata agcgtaaatg
     7621 aaaaacactg cttgaacagt tgtcacagac tgtccttgca gtgtttttgt ttaggcctgt
     7681 tttttcaaga actcagataa gaggaataat cccttttcca aggtttcttt tttacaacag
     7741 taacctagtc gggcatgctt cggtaaatca aaggcacttc ctggtactaa tagtactcct
     7801 gtttcttcta ataaattgat acaaaatgtc tggtcatctt cttcgatggc taatttaatg
     7861 aaagaagtag agacgtaatt gggagcgaca agttcaactt tcggttcatt ggctacccat
     7921 tgttttaaaa tcacaaggtt ctctgtaatg atctttttgt ttcgcgccaa tattttttct
     7981 ttattcttca atgcatgtac agcaagatca tctgacagga ctccgccgca aatcatcgtg
     8041 tagtctcgat actttcgaaa aacttctgcc aactcaggtc cagtagctgt ccagccaata
     8101 cgaatacctg gaatggagta ggttttggat agggaattgg ttgctatacc tttttcatag
     8161 acatctacga tcgacaagaa ttcaccttta tccgttaaag gcgcatatac ttcatctatc
     8221 aatacatatg catctactgt acgagcaatt tctgcgattt tttctaaagt tttccgatct
     8281 agcaatgtgc ctgtaggatt gtttgcacta ttcaaacaga tgatttttgt ttcaggtttg
     8341 actaaggctt ctagctgttc taaatcaaac tgccaatctt cttcttcctt caaatgaaca
     8401 aagtcaacag cggcacctaa agatttgggg atgtcatata attgctgata agtaggaagc
     8461 atcgaaacaa catggtctcc tgcttccact aacgcgtata gagctaaaag attagcacca
     8521 gtcgctccat tcgtttgtaa gatgttttcc ggatcgacgg tttgataaag agaagcgact
     8581 tcttgtttga aaacatctga tccttcgatc cagccatagt ccaatggttc gtttttgcgt
     8641 ttttcgaaaa atttacttac gctagtccca tctaagccaa cgagttcgtc taatgtcaat
     8701 gcttcgatcg agctttgtgc aatatcatat accgctttct tttcccattt atttagccat
     8761 tcttctacac cgaaatttgc gattttcatg tttctttccc ccttatatct tgatccagcc
     8821 tacagcaagc aacccgattg aaagcagtgc ggccacacaa atcagcccaa tcattacttt
     8881 ttcttttccc gtaatttgat gtttggtttc acgacaagcg atccagtaga agcaaaaacc
     8941 aggaagatag gcaatactac ataaaaggac ataagaaaat cctgctaaaa tgatgcccat
     9001 caattcaaaa actacagcaa tcccaccgat cactacttgt tttttgattc cttcttttaa
     9061 agaaaactgg acttgataga tcccgacaag tagataacaa atcaaaattg ccgctgtaca
     9121 taaagaatag gcaaattgat aggcataatc agtaactaag aaagtcaata agaatagatt
     9181 agtcaagatt gcagtaacaa ctaacgaata agttggggca ttttttttat tcgtttttcc
     9241 ccaacctttc ggcaacagac cgtctcgagc catcaacatc gttgtttctg ctgggagcat
     9301 cgtccaagac aaccaagaac caatgatcga aataatcaag ccgatattga tcagcgctgc
     9361 tccccaattt cccacgattc cttttaaaat atttgccata gcaggttgtg aaatagttgc
     9421 taactcttct tgagataaga cgccgtatgg caagatcgaa gcaaggatat agataaacaa
     9481 taaacaaagc agaccaatga tcgatgcttg ctgggcttct gaacgtttct tcgcgcggtt
     9541 ggctaaaaca cttgcgcctt cgatccctac aaagacccac atcataacca tcaaacaacc
     9601 tttaatctgc aaccagatcg ttccttgctg ccctgttcca ttcactagat tatcagatac
     9661 gttaccccaa aaatcagcag tgaatatatt cactttaaat gcgataaata caaatattaa
     9721 aaataggaat aatggcacta atttacagat cgtcacgatt gtattgatga cgctcgctcc
     9781 ttcaactcca ttgtttacta ataaagtcag accccaaata aaaatacttg caaataaaat
     9841 agaaggaaca ttttgtccac ctttgaatat cgggaaaaat tctcccatgg cgctcatcag
     9901 catcgttgca aaagcaacat ttcccagcca cgcagacaac cagtaacccc aaccactgat
     9961 gaagccacct aatttaccaa atgaagcttc cgcgtaaccg aaaataccac catctagatc
    10021 tggacgcttt tctcctaaat gattcagcga taataccaaa gctaaaatac caatcccaac
    10081 gattatccat gaaaggatcg ctggccctgg agctgcagaa ctagccagat cacttgtgat
    10141 cccaaacaca ccgcttccga ttgacgaact gacaaccaga gcaaccagtc cccatttgct
    10201 aatacccgtc gatttctttt ccatttccat caccctcact tataaaattg aacaaatcac
    10261 ttgcaaaaga ttcccttcta ttttgcaact gctcttgctt aacaaaaagc aactttattc
    10321 atattattgg atattatgaa ctttttacac aagtatttca agtataaaat gaataaaaat
    10381 taattttatt gcaaaaaaac agctatgcta tccaaaagaa aaggtgtttc ttttgttagc
    10441 catagctgtt ttgattcatt taatatcgct taaacgtatt gtaaaacttt tgtttcttga
    10501 tatgcgtggt cgatcaaacc accacccaga cattccattc catcataaaa tacaactgct
    10561 tgtccaggag tgattgcacg tacaggttcg tcgaatacga cttctgcacg attatcatcc
    10621 aataagcgaa ctgtcacagg aacgtcttgc tgacgataac ggaatttcgc tgtacacttg
    10681 aattcttttg gcattggttc attcgtcgta aagtggattt cacttgcatc caagcttgtg
    10741 gcatacaatg caggatgatg gaacccttgc cccacatata atgtgtttgt cgctagatct
    10801 tttcctacaa caaaccaggg ttcttgcgaa tctcctccgc caccgatccc tagtccttga
    10861 cgttgaccaa tcgtataata catcaagcca gcatgttgtc ctttgacttc accatcaaga
    10921 gtgaccatat ttcctttttt tgctggcaga tagttgctca aaaattgttt gaagttcttt
    10981 tcaccaataa agcagattcc cgttgaatct tttttcttag cagtcgcaag gcctgcgcgt
    11041 tcagcaattg cccgtacttc tgatttttcc atgccgccta gagggaacat cgtttttgaa
    11101 agctgttctt gtgataattg gctaaggaag taagtttgat ctttattatt gtctactcca
    11161 cgaagcatgt ggaccacgcc gttttcatcg cgagtgactt gcgcataatg tccagtagct
    11221 acataatcgg cgccaagatc cattgcataa tccaagaatg ctttgaattt gatttctttg
    11281 ttgcacatca cgtctgggtt aggtgtacgt cctgcgcggt attcggctag gaaatattca
    11341 aatacacgat cccaatattc tttttcaaaa ttcacagagt aataaggaat cccgatttga
    11401 gcagctactt tcgctacatc cttataatct tccgtggccg tgcatacacc gttttcgtcc
    11461 gtgtcatccc aatttttcat gaatattccg atcacgtcgt atccttgttc ctttaacaaa
    11521 agtgctgtta cagatgagtc gacaccgccg ctcatcccta cgacaacgcg tgttttgctg
    11581 ttgtctgtca tgatatcacc atcatttcaa ttagattctg aaacatctac gagttgaagg
    11641 tcgcaacttt tcagtatttt acattatacg tcatatttct gaaaatttca tcccttaatt
    11701 atcaagtcgt aaaaatactg ttctactgga cctattcagt acacaaacat gatagtcaac
    11761 caaaaaatca ctcatctttt gagcattcga tataaaaaat tggcatactc ataaaaaggg
    11821 ccagcctttc ggcaataagg aataatttta taaattgtga aaaactattt ttcaaaattg
    11881 cttcttatcg cttaaagctg cacgtctcat ttacaacctt ttctttttag atgttatgag
    11941 ttgctcagat aagtgatttt gtttactcta agaaaaaagg gaggcaaaag atacatgaat
    12001 tactttatca gtgatatgca ctttttccat gaacgcttat taggaaaaaa cgactttgct
    12061 ccgcggctct ttgcaaatgt ggatgaaatg aaccaacagt tgatcactag ctggaatgca
    12121 gtaataaaag aaaccgacca tgtttatcat ctaggcgacc ttgctatgca tccgcaatat
    12181 gaaaaagcaa atgcagaaat tttggaactg gtcactcaac tgcaaggaac aatccacttg
    12241 atcaaaggga accatgacag tcgcgctttt ttccgttatt tagaaaaaaa tgatcctagg
    12301 cttactgacg gaagtcccaa attttatttt tatgatgtag gtgccatcgt taaattcgac
    12361 catcaacaat attacttgac tcattatccg atgttgctcg ggcctaacga cactatccgc
    12421 aatcttcatg gacatatcca tcattacagc gtacctatcg agaacgatgt caatgtaggc
    12481 gtagacgcac cggaaagaga actcttaaag gaaaaactac catttggcac tccgttatct
    12541 gagcaacaaa tcaaagaaat ctatgaagca aagaggaagt acgataggtc gtgaaaaaac
    12601 tgccctatat caagtattaa acaaataaag ataattactc atatttttca tttgagtagg
    12661 cttattgcca caggaacatt aggatcagaa atggagttgt aacaagactt ctgtcacaac
    12721 tccattccat actattcgtc tttttgctca tggtgttctt ttaccagttt tttctgtaat
    12781 tctttatcat aatttcgggc agctgacgtt aaaaataaaa cgattccgca taataaaatc
    12841 ccgattccgg aaaacaagaa cattttttct acccctaaac gatcagctaa tggtcctgca
    12901 aataataatc caattggacc tgccaggttc atcaaagagt tgaagttccc taagacacga
    12961 cctaaaacat tcgattcata actctgctgg atcattgcca tcagcagtgt attgaaatat
    13021 ggcgttgcac aacctgctcc tgcattcaag ataagaaagt acaagaaccc ttgactatcg
    13081 tttggaacca atccgcttgc accgatcgtc aggcccataa tgatgtaggc tataataata
    13141 ggtttcattc ggtctttcca tgttcctata aaactgatca gtgcaccgcc taagagcatt
    13201 ccgactgcgt agactacttc cactgctccc gcctgtccaa cggaaccacc aaagtaatct
    13261 agcgtcatca atggatacag actgattgct ggcatgaaca acagcatcac aaatgcacca
    13321 ttgatcgtta tgtaccataa ccctttatta tccatcaatt gctgcagccc aaattttgca
    13381 tctttaaaaa tagtaagcgg aacttccaat atttcaggag aaacttttgg gatcttcaca
    13441 aaaatcaata agccgacacc aaaaactgcc cccaatacat ctaataaaat aaggtaattg
    13501 acaggaacga ctgaaaacaa agccgcacct agagctggcg caatgatgaa attcgctgat
    13561 tggaccattc ctaactgtcc attcgtcctt gttatgtgag aagatggaac gattgtcggc
    13621 ataatcgact ggatcgttgg catttggaat gtttgtgcga ccgaacgcat aaacaaagac
    13681 acaaaaacta gccaaatcgg gaaggattct gaaatcgttc cgactactgc taaaataagc
    13741 gcgaaaatcg ctacaataat atccgtgaca atcaaaagag cttttttatc ccagcgatcc
    13801 actagcggtc ctacaaatgg gcttagtaaa accatgggaa tcattcctag taaagtagca
    13861 aaactcaaaa ttgtcgccga accggtttct cttgtcaaat accagatgat cgcatattgg
    13921 acgaccatac tagtgattcc tgacaaaaac tgtcccgata aaaagaacaa ataatttctc
    13981 ttccaattcg ttaaaacgac cgactgttca ttttccataa acatccctct tttctttttc
    14041 attttgtata gcgtttgcac aacaatcatt atacgggatt cttttttcaa aaaatacctt
    14101 tttccctaaa taacaatcgt ttcaatttaa atttctttac ttagaaacaa taaatcagca
    14161 aaatattaaa aataacaaca tgtgttaaat ttaaaaataa aaaagacaac taatttgcgt
    14221 cgtccttaca aagttagtca tctaacaata ggccgtttca aaactagttg tctttttata
    14281 tccacagatc attcgacttt ttcgaataac ccacggctaa tcatcccatc catcagaaaa
    14341 taaaatttat cttggctcat tttctgtttt ggatctttga aaatattgac tgctttcaat
    14401 ccatttgctg tagtgatcga cattttcaat gtttgaatat cttttgatac agtgattttt
    14461 aatttgaatc cttctttgct ttgcggcgtg gcatctaatg gtcggatcaa ttgataattg
    14521 cctccgtttg tttctgtaaa tccattatcg cgcaatgtat atctttttgc atcaggatgc
    14581 aaacgatagc taattggtgc gcccagtacc gttgctgttg tttcaaatgc catgattttc
    14641 acctcgataa aattagtttc tctttattat aaaagtttat cctgattttt actaggtttt
    14701 tcagttaagt tccctaaaaa atgaaggcgt tctctcagac atctgttcat ataagaatga
    14761 cttcactagt tattttttga cagcacgaac taattgatca aggaaatact ggatgtcgtc
    14821 ttcggtattt cccaaaccaa agctgatacg gatggattct tttagtatcg gtgtatcttc
    14881 tccatacatt gcttctaata cgtgtgaagg ctcgatattt cctgctgtac aagctgaacc
    14941 agtagaaata gcgaccccat taagatcaag cttcatcagt agcaaatcat ttgcttcgcc
    15001 aattaagcga agattcaaca catgagggag tttattcgtt aaatcaccat ttacttgata
    15061 agggatttcg tttgcttcta atgtatcaag aatcaattgc tggaatcctt tatatttgtt
    15121 gttacgtgct tcacgttctt caggtgacag cagttcaact gcttttgcca taccccagat
    15181 ccctgctaaa ttttctgtac ctgcacgccg cttttcttcc tgctccccgc ctaaaagcaa
    15241 tgcagggata tttactccgt ctcgtttata taagaaaccg acgccttttg gcccattgat
    15301 tttatgagca gagatactta ataaatcgat tcctaattct tctggatgga tcgtttggtt
    15361 tccgtacgct tgtaccgcat ctgtatggaa ataagctgga tgatccgcta aaagttcacc
    15421 gatttctttg attggcatca aatttccgat ttcattgttc ccgtacatca cagagaccaa
    15481 gatcgtatct tctcgtaacg cttttttgac ctcttcgatc gacagattcc ctttttcatc
    15541 tacaggcaga tatgtaacgt caaacccctt tgtctctaaa tatttcatgg tattaagaac
    15601 agcaggatgt tcgatagctg tagtgattag atgtctgcct tctttttgac gcgagaacgc
    15661 tgtttctaag atagctgtat tatccccttc tgttccccca ctgttaaaga tgatctcgtg
    15721 aggttttgct tgcagactgt ctgcaatgat ttgtcttgct gtttccaatt tttcatgcgc
    15781 gtggcgacca aatccatgta tgcttgaagg atttccaaac gtgtcttgca tgattgccgt
    15841 catcgcttca attacttgtg gatgcatggg ggtagttgcc gcatgatcca gataaatagt
    15901 tttcacttca ttcatccctt ccaaattatt gctaggcaca ttctagcata aaatagcgaa
    15961 caaaccaaag aagagctcat ttttgtctag aggacgtttc atgggcatag aaaaaaggag
    16021 ctgtgacaaa agtcttgtcg cagctccttg aagctgctca cttctgtcac aacttctttc
    16081 cctctttttt ttgtttattc gaattctttt tcttccagac ggaataacgg actcatcggt
    16141 gtattttcat ggatgcgttt gaccgcttca cccattaatt ctgaacatgt aacgattgtt
    16201 aagttttctg gatgacgatt ttcttctgtg aaaacagaat cagtgataca aatatctttg
    16261 attggtgcat tgtctaaaat acttttcgca tgatcggaca ataatccatg tgacgcacag
    16321 gcatatactt cttttgcgcc gttttctttt aatacatttg ctgctcgtgc aagcgttgct
    16381 cctgtgttca agatatcatc taccatgata catgtctttc cttgaacatc accgatcaca
    16441 taaccaccct cagttgaagc atcatctgca tgatctacga tggctaatgt gctgttcaaa
    16501 tattctgaaa gactacgtgc acgctgaaca ccgctgtttt ttggcgaaac aactacgatg
    16561 tcatctcccg tcagacctaa ttgacggtaa taatgagcaa acaacggcat cgtaaataaa
    16621 ttatctacag gaatatcaaa gaatccttgt acttgaaccg tgtgcagatc taaagtcagt
    16681 actcgagttg cccctgcttc ttcgatcaag ttagcgatca atttcgcagt gatcggttca
    16741 tgaggtttcg ccgtgcggtc ttgcctagca tacccatagt aaggcaatac gacattgatc
    16801 gttttcgcac ttgctcgctt cattgcatcg atcatgatca gtagttccat atagtaatca
    16861 ttgacaggtg cattcgttga ttgaacgata tacacatgat cccctcgaat actttcttcg
    16921 atattgatgg aaatctcgcc atcactaaat tgcttcacga cgcttttacc taattctgtt
    16981 ccgaacactt tcgcgatttt ttcagctaat ggacggttgc cattcaaact aaaaatcttc
    17041 aacgtgtcat cctgatactt attactcatg tagtcctccc caaaacttct ctattcttcg
    17101 atagtttaac atatttttcc aagattttct gttaatttca gcaaattctt aaggaagtga
    17161 aactgttccg ttactccaac tggcaggaat gactttatga taatcgcccc agttgtcgtg
    17221 tactttgtaa taacgttctc ctgtttcagt ttcaaaataa gcgtacgctg tcacccaatg
    17281 attgccatat gtactgccaa gtactttcaa aataccaatc atcacaggtt tgccttcacg
    17341 tatacgtttt gtagctcgct gccatgaacc tagaagagtt gctcgtgcac gctcatgatt
    17401 gccattcttc tttaaaaaac tagaaatccc tgtactaacc tgaaaaggaa tcgtaggaag
    17461 tcctagtggt tggatctggc tacgcaatgc cttcgtcaaa accaacgaat cagccgtatt
    17521 tttcttgcga atctcatttg gaagcatcca ccccttacga tagtcttgat aataggcaag
    17581 gagaactgct gccgcgtaag taccacaaag atagcctgag ggggtagccc atttcttata
    17641 cctcaaaaaa cgttcttctg gcaatcccac ccagcaattt gcgagttcct ttcctgacct
    17701 tttttcttcg atcaaaacgg gaatatcttc ttttctgttg atccatctag ataactcgat
    17761 tggctcttca ttgatcagct tccatttttt acaagaaaga ccctcttgat aagtatattt
    17821 tgctggagaa tattctaccg gatgtcctga ttgatcgata atcacataac tttgatcttc
    17881 aaaaaccaga gctaaaaaaa gcaatttact ttttcttgac tgcagctgct gagtgctggc
    17941 taatttttta atttttttat ctactttgaa atataaaggt ttatccacta cttgattcag
    18001 ttgggatcgc ctcctttttt tcattataag tgaaggattg aaaaaaacaa atcagtttga
    18061 ttgttcgaat tttcaatttt ttatgttcta tttgttaatt ccttcatttt gtaagataat
    18121 gggcacacga aacaaaaaag gagcgatcga tgaatgaaca aagaacgatt gaaacaagat
    18181 ttctatgaag cagtcaatga agaatggcaa aaaacagcaa aaatccctgc agataaacca
    18241 gctacaggcg gtttccaaga tttagttgac gggatcgacc aacttttgat gggagaaaca
    18301 gacgatctgc ttgcccatcc agaaaaagtg tcttcagaaa aaatgaaaca tttccttgca
    18361 tattatcaac tggcaaacga ttatgaccga agaaatgagt tgcatgctca accgcttcaa
    18421 cctataatcg aaaaagttga atcattgcag tctttcgacg aattgaataa gcaatttcca
    18481 gaatggctgt tggatacatt accattgcca tttaatctgg atgtagatgc agatatgaag
    18541 aatgcgcaaa cgaacgcctt ctttgcttat ccgccttctt tattccttcc agataagacg
    18601 tattatgcat cagaccatcc caacggtgca caactaatag gcgttttctt tgatatggct
    18661 gttcagttat tagagcttgc cggcaaagaa aaaagtcagg cagaagcaat cacggaacaa
    18721 gcagtgcaat ttgataaatt gattgctcct catgtaaaaa gtgcagaaga aaacgcagat
    18781 tacagcaaaa tgtataatcc gcaatctttt gatacattta ttaaatacac agataaactg
    18841 gacttgaaaa aacttgtcac gggtttgatt gggacaactc cagataaagt gatcgtaact
    18901 gatccagtgt acttcgatca tttgaatgac atcctgacag aagctcattt tccgttattc
    18961 aaaagctgga tgatcattaa aacagtacgt tctcttagtg gttatctatc agaagaattc
    19021 cgccaagtca gcggaatcta ttctcgcgta ttgtctggaa cagacgaagc aatgcctcag
    19081 aaaaaagcag cgtattacct tgcctctgga caattcgatc aagtagttgg cgattactac
    19141 ggaaaaaaat attttggcga agctgctaaa aaagacgtag aacaaatggt gaaaaaaatg
    19201 atcgccgttt ataaaaaacg tctagaagaa aatgactggc ttggggatgc aacaaaagaa
    19261 aaagccgtca taaaattaaa taacttaggt atccaagtag gctaccccga taagatccca
    19321 gcattattcg accagttcaa aacagtacct gcagatcagg gtggtacttt gctttcaaat
    19381 actcttgttt tcagcaaact cacattaaaa gatcgtttca gcaaatggaa caaaccagtg
    19441 gatcgttcag aatgggaaat gagtgctgac acggtcaatg cttattatca tccatttcgg
    19501 aatgtgatcg tctttccggc agcgatcctt caagcaccat tttacagtct agaacaatca
    19561 agctctgcta attatggtgg aatcggagct gttatcgctc atgagatttc ccatgcattt
    19621 gataataacg gcgctttatt tgacgaatat ggcaacttga acaactggtg gacagaagaa
    19681 gatcttacac aatttcaaaa caaagcacaa gcaatgatcg aagaattcga tggtctgcct
    19741 tttgctgacg gaaaagtaaa cggaaaatta accgtttcgg aaaatattgc tgatgcaggc
    19801 ggtctaagct gtgcattgga agcagcaaaa acggaatcag atctttctat cgaggaattc
    19861 tttgtcaatt gggcaacgat ttggcgtaca aaagcaaaaa aagaatacca acaactttta
    19921 ctgcaaatcg atgtccatgc ccctgctaaa ctccgagcaa acgtgcaacc aaaaaacctt
    19981 gacgaattct atgaaacatt tggtatcacg gaacaagacg ctatgtatct agcgccagaa
    20041 aaaagagtgc gaatctggta agaggttgtg ccagaagtgg tcagcttcaa gaaataagaa
    20101 ggaatttggg aaaatcgctt ctcaaatttt tgtgacattt cggcttattt ttcgaagaag
    20161 ttacttctgg aataccatgt attagaggtt gtgaaaaagc tgcttagttt caagtagtaa
    20221 gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa atttgactta ctaccgagaa
    20281 actggctttt gaacaccgtt tatcgagagg ttgtgaaatc agcgtcctga cctgagtatt
    20341 agagaaaaaa acggaaaaat agttcctcat attttgccgt ttgttgagct aataccgagg
    20401 gtcagctgat tgaacaccgt ttagtggaga gattgtgaaa aagctgtcct gcatcaagta
    20461 ataagaacag ccaatcaaaa gcagcaagga gaacctcatc tataaaaaga tagaaggaag
    20521 tgagacatct attggtctca tttccttcta tttttacttt cctcagtcaa ttgttttaca
    20581 tcataaaagg agaaattcca cttatttttt tcgctgtttc atgacataaa caactacacc
    20641 gattaacaaa attcctccag ctaatgctag caacgggtta ttaaattctc ccgtttttgg
    20701 gagtccttga gtgccatttt tttcactttc ttttgctgtc ctatccggat gagaaggttt
    20761 tccatttggt tttccatttg gtgattcatt tcctggattt tctctttctg gtttgtcatt
    20821 tcccgggggc acatcggcag tttctcgcac agtgatcgct ttttgctggg taacagattc
    20881 tgtatgagca gaccattttt ccccatcaaa tatttccgaa cgataagtga cttctagcgt
    20941 atattctcct tttgaaggtg ctgaaaaaat agcggtatga ttagaaaatt gagcacttga
    21001 ctgtgtttca acgatttgga tcttttctgg gaaataacgc atatcttcaa agacaggcgt
    21061 tccttgattt ggtgtgaaag ttgacacaaa aactgtaaaa ggcttcagtt caatgatatt
    21121 tccttctgca ttctccgcca caccatttgc ttcttgtata ataatcggat tattttgttc
    21181 atttggtttt gtctgatttg gttcttgtac gattgcatac tctggatatt ccgaagacgg
    21241 tgaggtttct ccgtcaaaaa tagcacctac agataatgga agaccatcca ctctttcctt
    21301 ttctgtttga cgattccccg gtttaatctg catcagtcca tgaacatgga tacttccatt
    21361 ttcatagcgc gtaacaggct gctgaccttc tttcgaacat gtatttagag actcgatcca
    21421 atcttttgat atggtatgtc caagagtatt ttctgattgt ttctctcgtt cattccaata
    21481 gtagttcaac gagtggtaga tttgatcttc gttttgattc aatgggcgga tctgctctct
    21541 catctcaaga ttctctgttc ggaaagataa gataccagaa gcatggtagt ctgtgtttcc
    21601 tgctgaagag gtataaagag ccacattata tgaaccgtta ttaaaacttg tactgctatt
    21661 gacgataata tctgttccgc tattggaatc gattcctttc gcaagatttt cgaaagacaa
    21721 actattgatc aattcatgag ggcccgttaa agaagaaccg cccattttga atccattacc
    21781 gttaccttct ccctcaattc ctggtaccca gccgtttcga taagcaactg agtttttgat
    21841 gattactttt ccgatcgaac ctgtttcatt tttagcaaaa aggtcccaac cgtcatctgc
    21901 attatgatac gcgatacaac cgtcaaatac atttccttct cctattgtca gtttggccgc
    21961 aaatccatcg gcatcttcaa atcctggatc ggcattttca aaagatgtac agttcttgac
    22021 taagttatgc gcgggccatg cttcgaaagg atcatttgag ctaccgctga tttggattcc
    22081 tgtatttcca ttccgataag catgaatctc ttcgatcaaa ttatgatttc cagaaatctg
    22141 taatcctttt tgcatagctg cactatttgt aatgtcaaac cctcgtaaac cccagtagtg
    22201 actgaacagt gtcatcccat ttccagttcc tttaaaatca agtacaggac gcttgttttc
    22261 tggatttttc tctgcaatca actgaatcgg gttttctctt gtcccgttaa cgccttttgg
    22321 aatcgtcaat cctctttcga aggaataagt tccaggcgcc atgacgattg tctgcccagc
    22381 atatgcgtat ctcaatgctt gtgtcagaga taatggattt tgtctgcttc cgtttcctgc
    22441 atctgaccct tctggtgtta cataaactgt cgaatattta ggtttacggt agtccactgt
    22501 atgaagaatc tcttttgttt cataactagt catctctacg tattcttctg gcggatagtt
    22561 tttatctggc gtaaaactga aagtaaattc gttcgttcct tccatcagtt ttgtctgata
    22621 atcaaattcc cgattcgcag tgatagccaa gttttttgcg ttcttaagca cctctcctgt
    22681 tgctttattt ttaattgtca ataatccgtc agcatttgct ctaaaggaca tagtatgatc
    22741 ttggtttcct gaatgattac tagaggtcac agtgtaaatc ggatcaatca agcgagtagg
    22801 tctttcttgc ccaggaggat ctgtcgcagg atctgagtaa gcaacttcga ttccttctac
    22861 cttgatcgtc atattccttg ctgcagcaaa tcctgcataa ataaccgatt catctgaagc
    22921 gtataatttt tcccagtcat acatgatgtc agaagccatt tcttctcctg tttcaggatc
    22981 gtaataatat gcctctaaac cagtattcgt ttttttcatc tctacgtcca gtttagtaat
    23041 cgagttcgtg gccggaaaca gattcccatg accgtttccg aatatattat aagaacctgt
    23101 ttctttttcc aagaaccctg ctgaagtctc taaaggtgtt gtttccactg agacactccc
    23161 aggagctggc gcagcttgcg gatcttcaga tgatattcct gtgattgccc gtgtccccaa
    23221 tccaagtcgc atcgtatatt tgctgccgct cgtgttgacc acttcttgtc tatccgagtc
    23281 ccagacatat tcgatccgac tgcctagtat ggcaaatgaa tttgaataaa atgcctgccc
    23341 aaacaaatga ttttttggta ctgcgtctct taccattaaa gcaaatcctt cttgggcatt
    23401 cgtataggtc caagattcta tttcgatcgt cgcccgcatc ctaaagttga tgtctttggg
    23461 gattgcttga taataatagg tcattccatc tgatccgctt gactggaatt ttccgccgtt
    23521 attcgtggaa gagagccgca cgccgtcttc taatggttca atggcatacc tactagcact
    23581 tgtgctttct ccgaaaacaa cccctttcca ctcttcattt gcttcttcag attgcttttt
    23641 tgtcttttca ttttctgatt ctttcatcat aggatcattt ccttcttccg tatccatatc
    23701 ttcactagtt cttggtattt cctccattgt tgacatccct tcaatgttca cgtgtgcatt
    23761 ttcttcgttc acagactgtt gttcgttagc agcaacttca acgacagaaa ttaaaaccgg
    23821 ggtactgagc ataaggagat tcatcattag cgcactgtat tttatacgtt tttttaacaa
    23881 gtgtattcct cccgtaacaa attagaaagc gtttacttaa agtattacct aatttatttt
    23941 tactgtcaat aaaaaacaaa attataataa gtgtatttta taaaaagaaa aaatataact
    24001 taagttgttg ataataaaga gatttattaa cgtaaaaaga ataagttttt ttaaaataac
    24061 gtataaaaaa gagcataaaa caaagtcgtt tgttttatgc tcttctttta ttattttgtg
    24121 ctttttattt tatcaaatca ctttgttttt ttataaaatt tctgcgccta gtgtggactc
    24181 aaaatgtctc aatgcccatt catgtccaac gggatcgaaa cttgccacgg aatctttgaa
    24241 aatatggagt ttgtatccta gattatacgc atcgactgct gtatgcaaca cacagatatc
    24301 tgtacatacg ccggtcaaat aaatatctgt gatctggcgt tctcgcaaac ggatgtctag
    24361 atctgttcca ctaaaagcgg aataatgccg tttgtctatc caataaacat tttcctcttg
    24421 ctcatagtct tggtataaac tttttaaaga gccgtacaat tcccgtccac ccgttcctat
    24481 cacattatgc ggaggaaata agcggttctc cggatgaaag gaatcttttg gatcatgcgc
    24541 atcaatggca aaaacgacaa aatccttttg atcaataaac ttctttgtat gagcagtcag
    24601 ctttttttca attacttgtc ctgctgtccc agtagtcagc tttccatcct ctgcaacaaa
    24661 atcatatgtg tagtcaatcg agatcaatgc gttcatctta gtcctcctta tacgagatgt
    24721 ttgacaaatt cgatcaccat ttctgctgat cgtttgcctg cgtcttcgat aaattcgtca
    24781 aagctttgtg tcgccgagtg atctgctgtg tcgctcattg cacgtacgat caaaaatggg
    24841 atattgaact gacgagctgt ttgtccaaca gcggctcctt ccatttcgca agctaatgct
    24901 tcagggaaat tcgttaagat ttctttgatt ttatctggcg agtcgacaaa tgtatcacct
    24961 gtaacgatca atccttcttt tgcgttcaaa ttcgttgctt ttgctgcttt aaccatttca
    25021 ctgcgcaaat atgtgcttgc ttcataatat agaggcattc ctggtaattg tcctgggttg
    25081 tagccaaatc ctgttgcatc tgcatcaaaa taagctactt tgtctgatat aacgatgtca
    25141 cctacttgta agccttcacc gattccgcca gctgaacctg tattgatcac catgttcacg
    25201 ccgtattgtt ggatcaacag acttgtggta atagatgcta agacttttcc tataccggaa
    25261 cgtacgacga tcacttcgtg gttacctaat gaacctgaaa taaataaagc gcctgcgcgt
    25321 tcccatgata atggttcgct taggttctct ctcaaaattt ttacttcttc ttccattgcg
    25381 ccgataatac cgattttcat ctttttaatt ccttctttct atataaatgc gattgctaaa
    25441 aaaaccacac ataacattag gataacaata ataagagatt tcatcaaaaa agagttccat
    25501 ttggtcgtct tttcccgttc gctgatcctt gttttcgtga ttggtttatt ctttttgctt
    25561 tctttacgat aaaagctggc aatctttttt tcttcttgct gataagctgt ttctgctttt
    25621 cgctgttttt ttaatgactc gcttgcttgt gcttgttgtc gcttgcgaag ttcgcttcgc
    25681 gtaataagcg gtcctttggc cataagccga tccctctact ttcctttggt caatagttcc
    25741 cagtattgaa tcgcataaat cgtctttgca tcacaaatca actgatcttt catcgcttgt
    25801 tgcgcctctt caagagttag atgatacaac tccagtactt cgtcttcatc ttgtgctaaa
    25861 ggattctcga ccttctctac cccttgtgca tgataaatat gaaggacttc atttgcaaaa
    25921 cctggtgaaa gatacatcga agtaagatgg ctcagcgact tcgcacgata gccagtttct
    25981 tcttctaatt ctctagctgc tgtcatttcg ggattttgtc cttctcctgg atcgattttt
    26041 ccagctggaa tctccaaaat cactttttct aaaggttttc gaaattgttt gacaagaagc
    26101 agacgatctt gttcgtcaaa agcaatgatc ccgacaccgc caggatgaaa taccagttct
    26161 ctcttcgaag ttcctccatc tggcaaacga acttcgtcta cagcaacatc aataattttt
    26221 ccgctataga tttctttgcg actgattgtt ttttcttcaa attgctcatt gttcagcata
    26281 tcttctcctg ctttctttgt aatcataact gctttttttt catttttcaa tttttctcaa
    26341 aaactcctta ttagtttacc atagataaac cttagatttt ctctaaatat agaaaatcct
    26401 tctttagtcc gatactcttt ctagtagtcc gtatgctaaa ataagtatgt aatcgaataa
    26461 cgaaaagaat tcaatactca acgataaatg acatggaggg tttattatga taaaacgaaa
    26521 ttggccgtgg cttctagcat tggtcttgct atttctcttt gtccgaaaca atagtttttc
    26581 ttttgttcta ggacttttat tgataggtgt agttttagtt ttgtggggac tctttggttc
    26641 gcgcaggaaa aagggaaaac aagaagaaat tcctgcactg actgacgaac ttgaaactca
    26701 ctatgaaaaa agcggtatga cagcgaatga aatttcattt tttcgacaaa caatgaatca
    26761 aacaaaaaat gagatcaatc aattgcaaat gaatatgcag cagacagcca aacttaaagc
    26821 aatcgatctc cgccatgatc cagtcaaagc agcgaaagct ttattcaaag aattggtgaa
    26881 agaaccaaac cgactgcatg aagcaagtca gtttctttat acgcatctgc cgaatctagt
    26941 tgatttgaca aataagtata atgagatcaa tgaccatgag atcaaaaaca aacagaccta
    27001 tgaaaaacta gaagaaagcg cgcagatcat cgaccagctg tcagctttaa tcgcacaaga
    27061 ttatcaaaaa ttcgttgctg aggatctaga tgatatcgac gtagagatat ctgttgcgaa
    27121 acagagctta aagcgtgata ataaatatga accagaacaa aaggattaac tcttttgttc
    27181 ataaaagaag actcggaaca ttcagatgat gtctggctgt ttcgagtact ttttctaaag
    27241 tagagacatt catgtaagaa tcgagaacag attcaacaag gaggaatttt ttatggatca
    27301 taaaccgact gaaacaaaag atgttacacc agttaacgat acacttgaag atttattgaa
    27361 caacccgttt tcaactccaa cagatacgct gaccacttca caacaagcgg agattgatca
    27421 gctccaagag caacagacag ctgctcgttt aattgacaaa ctaccggcgg aacgccaaga
    27481 acaagctaaa cagctagcag caaaaatcga tgctaatgat gcacagtctg tcatcagcta
    27541 cggatcggct gcccaagcaa aattaagtga attctcacaa tcgatgttga atcatgtgca
    27601 agcacaagat attggtcctg taggagattc cttaactgaa ctgatgtatc gtctccaaga
    27661 agccaatcct gacgaactgc gtgccggaga agggaacatc ttccagcgtg tcttcgggaa
    27721 ggtcaaacaa tcgatctatg aagtgacagc aaaatatcaa aagattggtg cacaaattga
    27781 caagatttca gtgaaattag ataaagaaaa agacggtctg ctaaaagata atctgatgtt
    27841 agaacagctt taccagaaaa acaaagacta ctttgatgca ctgaatattt atatcgctgc
    27901 tggagaattg aaaatggaag aacttcaaac aacgatcatt ccagaagcga tgaaaagagc
    27961 agaagaaact ggcgatcaga tggatgttca gattgccaat gattacacgc aattcctaga
    28021 tcgtctggat aaacgtacgc atgatcttcg cttagctaga cagatcacga tccagcaagc
    28081 accacaaatc cgtttgatcc aaaacacaaa tcaggccttg gctgaaaaga tccaagcatc
    28141 tatcgctaca gccattccgc tgtggaaaaa ccaagtcgtg atcgcattga ccttgcttcg
    28201 tcaaaaagat gcagtaactg ctcaacgcca agtctctgaa acaacaaacg acttattgaa
    28261 gaaaaattca gaaatgctga aaatctcagc catcgaaaca gcgaaagaaa atgaacgtgg
    28321 aatcgtggat atcgagaccc ttcaaaccac tcaaaatgat ttgatcgaaa caatccaaga
    28381 gacattgcgt atccaaaaag aaggaaaaga aaaacgtcgt catgcagaag tagagcttgg
    28441 acacatggaa gaagatctga aacaaaaact gttggattta acccaataga tcacctttcg
    28501 cttgttacta aaacaaacgc ccaacaacag tttattacaa ctgttgatgg gcgtttttct
    28561 tatctttctt ctaacttctc cattggagtc tatttctcat tcatcttgct gtgtccatag
    28621 ccatagccaa aataaatgat cagtccaata accattacga taccgaacac gatccatgtc
    28681 acagtttgca gacgaagcat caatacaata caagtcaaaa tggagacgat tggcaatagc
    28741 ggaacgaatg gcactttgaa ttctccagct tttggtttgc caaacatttt tctcaacttc
    28801 agtaagccta gactaacaag catcaaatag gcgagcgcca tgatattcgt tagttccgct
    28861 aatacattca atgggaaaaa tccggcaaag aatacagctg ccacaccagc ggcataagtc
    28921 gcttttttcg gtgtacgatg cttttgatcg atttctgtca taaacttagg aagtaagcca
    28981 tccttgctga cagcaaacag taaacgagca agtgaataca tcatcgagat cgttaccgtc
    29041 agtagcgtta aaattgcccc tacagcgatc accgcgccca ctgttccatg tcctacatac
    29101 ctcattgcaa aagccactgg gtcattgact cctagttcag tatacggaac gattcctgtc
    29161 aagatcagcg tcacgatgat gtaaaggaca gtagcaatca gtatcgaacc aatgattcct
    29221 cttggcacat ctttttgcgg gtttttgact tcctcggctg ccattgcaac ggcatcaaat
    29281 cccaagaaag caaaaaacac aagagctgca ccatctagca caccggaaaa accaaaaggc
    29341 atgaatggct gccagttatc aggtttaacg aaaaatattc ctacaatgat aaacaacgcg
    29401 atgataccaa atttgacata taccatggca ttattcaaac gtaatgcttt cttggcttca
    29461 agcgacacga tgtaagtgac gaatatcact acgagcaccg caatcaagtc aatgtatgta
    29521 ccattttccg gattgtaccc gccagttaat gcttgtggaa gttcggcccc taaacttttc
    29581 aaaaaacctt gcatatagcc agaccatccg gaagcaacag aggaaaccgc tagtaaaaat
    29641 tccccgatca acaaccaccc tgtcagccag gcagcaaatt caccaaatac aacatacaga
    29701 taggcatatg gcccaccaat cactggcact cgcgaagcaa attctgcgaa acttagtcca
    29761 gacaaaatga caacgattgc agctaagaca aatgaaagtg acagtgctgg accagcattt
    29821 tgattggccg caacccctgt caccacaaat attcccgtac cgatgatcgc accaattcca
    29881 agcatgatca aatcagacgt ttttagttct tttttcatct cactcgtatg attgagattg
    29941 atctctttct tacgaaacaa atccattgaa gttcctcccc attttaggtt ggaaaacagc
    30001 gattaaactg ttttcatata ccctaaaagg ataccaccta aaatgactaa aaggcaacca
    30061 acaataacat aaatgagctc ttttttcgtt tttctttcgc caaggatgaa aatcccacct
    30121 aaagtagaga taatgatccc catttgtgaa agtgagaagc caacagctaa accaagtgat
    30181 ttgactgtta gaagcatgca gatgtttcct aagccccata ataatccaca gatcatgttt
    30241 ttccacacaa actgatcgac tttaacttta cggaaagcaa agaagcttgc gcctaagatc
    30301 attccgatac tttgaggtaa gataattgac atcgcatcca aattcgccca gttgacgatg
    30361 atggtatata caccataacc aatcgtagag aagatcaatg ctctaaaacc cttaccaaaa
    30421 tcaagcattt tattatctgt atctattttt ccttcgtcat cttgtcgggc agtcaaatac
    30481 gcaccgctta caagaagagc taaagcaata ataccgtata cataatcttt cgtttgtgtc
    30541 cattcatgga agaaaacggc tcccgcaatc gtattcaaaa ttaattgaaa accagtagac
    30601 aatggtagcc ctacagaaac acccatgtac ttcattccat ggaactgtcc attttgtcca
    30661 acactccaag ctaagccgga taaaaatccg atcaagaaaa tccaaggggt gattacagga
    30721 ctaacaacga aaaagacaac taaagaaaac agaaatgcac cgatcgtcat tcctagtgtt
    30781 tgttgattgg catcgccacc aattttacca cttactaaac caatactacc ccatgccaac
    30841 atagggacta atgctattaa aatttccata accaatctcc ttttatttca catgataaga
    30901 aacttatcag cgaaaacgtt aacaacacaa gcactttttt tcgtttctaa cgattttcta
    30961 acgtttttca ttataaaaat ttaagattgg gaaaaataaa gtcattgttg tcccttttcc
    31021 ttcagttgat tcagccgtca aatggatacc taatttttcg gccagatttt ttgctaaata
    31081 aagtcctaat cctgttgaat gtgttttgct aagtcgacca tttctcccag taaatccctt
    31141 atcaaagatc cgtttcaagt cttccgctgg gataccgatc cctgaatctt taactgaaag
    31201 gctgactcct tgcgcttcct tttctatgct cacaatgatg tttccgtgat ccggcgtata
    31261 tttgatggca ttactaagca attggttgaa gataaaagcg atccatttag catcggtcaa
    31321 aacagtatga tcctcaccaa cgatctcgta gcgaatattt ttttggataa aataatttgc
    31381 ctgactgcgt atcacaggct gaatgattcc ttttagtcca tattcttgga tgaggtagtc
    31441 ccgcgagaaa ctgtcgagtc ttgcataata caaaacttgt tctacgtatt catcgatttt
    31501 tgataattca ttttctagta atgtatactt ttgatcgtca atatcgaact cgatcgaacg
    31561 aactagcaat ttagaagcgg aaagtggcac tttgatttca tggacccatg agtcaatata
    31621 atctttttgg tcttgttgat tactgattgc tgattgcatt acttcttggt gttcacggat
    31681 cagctgattg atatattctt ctaccagttt ttcttcttct gtcctcccac cactcaaata
    31741 attttgcaaa ggggaagttt tttgtatgtc ggctaatttt ccccaccatc ttctcttgct
    31801 caagtaacca cccagcagat aaaaaatcag aaagacgccc tcaatcaaag ctaaataagc
    31861 aattgtgctc aaatcaactt tgatgtttgg cgccagccac atcacaaaga tcgtcaatgc
    31921 aataaaaaac agccatccca agatcaatgt ccactgatct ttcaaatatt taaaaaaatt
    31981 catcttaacc gctcatcctt tcagggaacg atatatccct gtcctacttt tgtttcgata
    32041 tatccttgga tacctgcctg ttcgattttt cggcgtaacc gattgatgtt gactgtcaat
    32101 gtattgtcat ctacaaatcg ttcgtcatcc cacagtgctc gcagcaattt ttcccgactt
    32161 aagatctttc cattgtgctt catcaaaata aataatagac gatattcatt tttgctcaaa
    32221 tcaatgatct ctccgttgat ttccatactt ccgttgtcaa cattcaacgt aatgccattg
    32281 tggctcatca tttcactaga taattctgtg tagttgtaag aacggcgaag taatgcattg
    32341 atttttgcaa tcagtacatc gatttggaaa tgttttgtca caaaatcatc tgcccccatg
    32401 ttcatagcca tgatcatatc catattcgta ttcctgctgg agataaaaat gatcggtact
    32461 ttcgatactt cacgtatttt ttgacaccaa taatagccat ccaaaacggg aagattaata
    32521 tctagtaata caagctgtgg ttcttctctt tcaaagtctg agaacacttg attgaaatcg
    32581 gtcgttccaa aggtttcaaa ttgccatttc tcaagttcct ccatgatcaa ttgtcgaatg
    32641 atctcttcgt cttcgactac catgattttt gccataaaaa atccctccat ctttcttctt
    32701 gctactacaa tatcaaagaa gcccttgtga aacaagttgg cttacctgga aaatgtcatt
    32761 ttagcaaacg ttaaaaaaaa ctggaaatat gcgatttaat cgcgtttgtc tcttccaagc
    32821 agcttaaatt tattatgtta ttcttaataa ttggtctatt atctgttatt tttctttcgt
    32881 tgtttttgtc ttttaaattt tcgataacac caataaccga aaagcgttag cactagcaat
    32941 atacctagaa ggagtataag taatcgataa agatggtatt tttttgtctg ttctatcttt
    33001 gaagagactt cttctgtaaa gggaactcgt cttcctgtca ctagtaatcg gtgagtgttc
    33061 acggtgtaag gtgtacaagt gataagtgtg actagatcct gcttttctct aattgctaat
    33121 gtatttgttt ttgttggaag gacaacaatt ttctcaacga cttcataagc gagcatccga
    33181 ccatacactt caagatagaa tcggtcatct tgctccattt cttcaagatc cgtaaagagt
    33241 tttttctcag caataccgct atgggcggta atcacggaat gtgtactctc tcctccagtt
    33301 ggaaaagagg tgccttgcag gactgtcgct cctctatcta acaaaagatc attcgtttca
    33361 tcaaataaag gcaagctaac attgattttc ggaatataga tggctccgat catatgttgt
    33421 tcgtaatatt cttttcctgg attttggaca tttctaaccg cttgctcaaa aggatctttg
    33481 acttgtccca ttcctgggat tactgatgta tgagcaagcg tctgattttt cttttcatgc
    33541 actgctaatt gttgctcatg tttttcttct ttatcgcgtt caagctgctt ttgataattc
    33601 tcgatccttc tttgatccaa ataattgctg agagcatctg ctaaaaatgg atatgtaaaa
    33661 actgcagctc cggcaagaaa catcactgcc ataaataatt gtaataaaag actgatttgg
    33721 gtttgaggtc tattacctat tttctttttc attttcttca ccttcttatt taaaaaaact
    33781 gcagcaacct ttataaaacc gattgctgca gcttattttt gttgcttata cttcagactt
    33841 cattttagat ttacggtacc agctgtacgc tccaatcatc aaacttattc cgattagtaa
    33901 gaatgccaag agcccgttcc caccagtagc aggaagtgac ccgcgtttca tattcggtac
    33961 tctttctggc cctggatttt ctactcctac gatctgaatt tcttcattat agcttccata
    34021 agagatgata aattcagtaa aggctgcctc acctgttgga agtacataac cttctggcgc
    34081 catggtctct ttcatttgat aggttccata atctaaccct tgaacctcaa agtatccatt
    34141 tccatctgcg acaaattctg ttgcttgtcc gcttgttgcc cactcaattc tatctgctcc
    34201 tgattcataa acagctaaag gcgactcccc tttataaaat attgcgtatt cagaacggtc
    34261 ttcattccac aattcgaatc ttgcatcttt aagcaattca ctgcttgatg catcatattt
    34321 ttcaaacttt cttccacctg ttgtgacttt ctctggcggc tctactcctt cttcataatc
    34381 aaattcatca tttcgtccga tttcaataac cgctgtgttg ttatggaaat catccgcttc
    34441 tagttctgtg gaaaccttca aattatacgt gatcgttaaa tctcctccac gtgcatctgc
    34501 taatctacct aaagtatcta ctttggctac tccattttct tctgtcaaaa tcgtcacgac
    34561 aaacccgttg cttactactt ctactatata atcttgtcct tttgttaaaa tcgtctcgcc
    34621 ggctcgcact tctatttcct gatcataata agttagacca actgtaggcg tatctgtgat
    34681 tttgtaattt ttgataacag cgcttccgtt ttcaaggaca gaatcgatga aataaggaat
    34741 aggtgctgtg atcgtgtaag aagccgtttt tcctctttct agatcaatat aagaaatcgt
    34801 ttcttgttct ccagcttcat taataatcgt tacttgtcta aggtcgcttt cctctacatt
    34861 catctgttta tctgcttctc tgatttcgtt tttcggatac aaatgcacat ctgtattgta
    34921 tgtgtctttc catgtagaac catcccacac gccatccacc atatcaggca tcatcactgg
    34981 catcataaca accattggag acgcgattct ggaaatatga gctggcgaat aagtttctaa
    35041 gaaaagatag actttatctc tagaagaagg tgcttcttcc gtcacttgga cggtagagaa
    35101 taccgcttct ccagcttcat tcgttgtttg tttgtcaata cttgtcagtc gatattttaa
    35161 aaaccaactt tctgtgtgcc gtttttgaat ccattcaatc gcttcggcag aattaagacc
    35221 gtcttctcgt tccggtgtta aaggattatc tcgaatcaaa tcgtaatata cttccgttac
    35281 gtcaaacaaa tcaaaatcga ctcctggaat attttcttca ccaaaatccg tagaaaccaa
    35341 tccgctattc ggtcgttctt ccggaacaga tgagaaacct tttttgtgta atgtaatcgt
    35401 cacttcactt ggtttttgtg cgacttcttc ggctttgact agttttccgt tcccgaaaat
    35461 ccctattccc gcagtaacga gtaacagtac actcattccc gtgacaatca tttttttatt
    35521 catttttttc tccccgttct ttttttatta ataaaacagc acctaacaat aaaagaattc
    35581 ctagtaaaga aatcaacgtt cttgcttcat tcgtttgcgg gaatacggac cattttcctg
    35641 attgacctgg attgcttgga ccactcggct ctttcggttt gtccgttgtt tcttttacgg
    35701 tctcgttata aacacgtggt gttgcggatt cataggcaga gactggaact ttcccggatt
    35761 ctaattcagc catctcctgt ccgttaacta ctacatattg tggttggcct tttgcatcca
    35821 cccaaaattc agggatgatg acctcgattc tcttacttgc ttcatccatc tcgtaacctt
    35881 ccacaccttt taattcttca aaataatagg tgccagaagg caagaaacgt tgtcctgtcg
    35941 taacaaggcc ctctttatcc gaaatgaatt tgcttacatt tttgtcattc aaaggatcat
    36001 tgtctgctgg tttgatccat tgatttttca agtcattaac aggagccata tctaaataat
    36061 atttcccccc ttctatcatc tgatatagag caaaaacagc accttctaat ggttttcctt
    36121 tttcagttgt tcctctttga cgtccatact tgaagaagta tggatctctt agataaccga
    36181 catttttagg atagatatga atctcttgca gttcctcggt tgattctgtc gggtgataaa
    36241 ttggcaaaat agcagcaatt gggatagctg tctgatcgat atcaacatcc aatccaactt
    36301 ctggatcaat cgattcttcg aaaatcaaat aaactgcatc ccgatcttgg tttttcttag
    36361 gtgctttgat acgtgcaatc ccgtctccta atccgccaac cgtatctttc ccagttgtta
    36421 ccgaagtccc tatttggaca agcctttctt ctgtgattag ctgacggata ttgtttctgt
    36481 tcgtttcagc gatttgctgg acgaattctt taggagtcat gttttcagca gctttttttt
    36541 catgataata atcggtcatg tcgtaaatgg caaatgtcgc tccatttagt ggcaccgtct
    36601 gtgaaatgat atctgctgtt tcccctgctt cctcagagat agccaagcca tcattttcat
    36661 ggtattcaaa ttgatcgtta taatcgatat ctcgaatcat ccgtttatgc aacacgaatt
    36721 ccacgacatc ttcccctgat tcttctgccg acatcgcatg tggaagaagg actgctgcaa
    36781 gcggtagtaa aacaagtaat tgaagcatca aacacaacag ctttttcatt accttgctcc
    36841 ctccttttta gattgtctga caaacaaacc ataggctgct cctgcaagcg ccatgaagaa
    36901 tgcagcaagc aggatataga ataatcgtcc ggatcctcct gtagcaggca acggattttc
    36961 aggatcgttc ccgacactaa gctgtaatct gattcgattt gtctccaaaa gttcatattc
    37021 taactcttgc tgtagatcag gcgtctctgc ttcttcgttt ggataatacg aaatctcaac
    37081 ttttagtgta cccgcttctt ttcctggaac tacccgatca ttttctatgt caggttcttc
    37141 tcgataacta atttctaaaa taaagtaacc tggaagtttt ctatagctgt caggtgactt
    37201 cacttccttg atccgataga ccccttccaa caagtctgaa gcattgaata gggaagaatc
    37261 gtttggatct ggtgccaagc ctccctcgat gatttcatac tctcctgcac tattttgttt
    37321 ctcaattgaa aattctgcgc cttcaagacg tcggctattc atactgtcaa ttttcaaaag
    37381 ttccaaatcg attggcgcta gttcatcttc taaggttact tgtagtacac catcgatgat
    37441 ttcatagcct tccggcaagg gagcagtttc gtcttcgatg accgtatctt caatgataaa
    37501 cttaccttct tcattcagtg caaactggaa cacttgatca gatagccgat acccatttgg
    37561 tgcgacagat tccgagacct catattcacc aatagacaga tgcagaggtt ggtcgtaatt
    37621 taaatcgaca tacttttcta ctcctacggc acgagaatag aagtatccga tcccaggcaa
    37681 acgtttcgat tcttctggtt ctaacggatt accagtgtat gctcgataca gcgggaagga
    37741 agaatccccc actttcctga tatcgaaacc tgcaccatct aatgtatggc cttcatggtc
    37801 taattttcta actcggatct cccgataatc aaacgtattg taagcagtga atgctaccca
    37861 taaacgatcc tcttcatctg ttgtatacgt gagatattgc caattttctt cacctgtttg
    37921 cttgagttgg atagtcccta tagcattatc gtaaagtcgc aagatccatg tgtcattttc
    37981 atcaggttct ttgaaacctt ctgggttctg gctctcaatg attttgtatt ctgcatagtt
    38041 ggtagtttct tcactatcct tataaacaaa tgaatctggc tctccgattg gatgaataac
    38101 tttctcacca tccacgatta catatttccc gtcttcatct actgaataga acgtgagtct
    38161 ccctttctct tcctctactt cgttcacacc agaaagccct ttcgctactg gatatccgat
    38221 ttccagtccg ttaccatctg tttcataaag ttcaaactct gcgccattga ttggcatatt
    38281 actgccttca attagtttat tgatattcat gtggattggc ttgaattcat ttcgcatttc
    38341 cagtttgaca tacaactcat catactctgt gccttctatg ttaggctctt gtacaacaga
    38401 aagcttgtga tattctcctt cataatagga attcggatct ttaccttccg gtccgccgac
    38461 tctcgaacca gatgtatatt catctacaag ctcgtagtga cctaacatct catcttcgtt
    38521 ggctgcatat tttttgattt ggaattgata cgtctcatct actaactgat aacgtggtgg
    38581 tccagcgatc tctctgatcc aaaatatgtc gctgactgct ccagtttcat ctcctaaaat
    38641 cggcatcttc gtttcaaaga tcgctattcc gtccgtggta gttttacttg tttcgattgg
    38701 ttcggcttcc ccactctctg gattttggtc atataatgca aattcgactc cagccaacgg
    38761 ctcgccattt tgacccttct tgctgacttg gaaattacgg cctttatgtt cgtaacgaat
    38821 ggaagaagat gggaaataca tccgtccagt agtgatatca ttctcataat cctccaggtt
    38881 ctgaatatag gccatattgt tcactgtgca aaaatttccg tcttgagctc ccgcatcaag
    38941 ttttacttgg tacttgatcc tgaccatttc cccttcacct aaagaaatcg gagaaaattt
    39001 ataagcttgg ttttcccgtc cgacatacgt tgtcggagtc gccactactt ctggtggggc
    39061 ttgtccatga cgttcttcat cccatatttc tggctcttgg tacttcatgc cgttttctcc
    39121 tggatctaga tggtaaaact gaatatctgc cgatctgcca gctccaaatg gtgagacatt
    39181 aaaaccagtt tcatcataaa gtgtggcttg ctggatcgtt ctcttgaagg tagaagagat
    39241 atcctccaag gctgtaacaa tgtcattctt gttgttcgca ttgtaatatc gcggtgttac
    39301 gccatcttct tctaaatcag caatattttt caatacattt cgtccaatag catctagtcg
    39361 ttgtctcccg ctaacgtttc catcgattcc taaaccaatg gagaagatac ttggcgggtt
    39421 ctcttgatac ttgtttttca gccaatgatg ataagcaact gtgttgatcg cagatgactt
    39481 ttcttgcgaa gtaggactgc cattcgtatt gttattagaa gaaccatcac caacccagtg
    39541 agtcgcttta ttatctcctt cttttacctc tccataacga tagtgtacat ttacttcatc
    39601 ttctggacgg ttaaagtcag atgcataggt aactggatga gtaaaccctg cattagaagt
    39661 attcccagaa aactcctcaa aatttctgaa caaaacgtca ttatcttcag caatcttatc
    39721 ttccatcaca gtccagttgc tccaagctcc attagtgctc gtacgataac ttgactgaat
    39781 cggtgcataa ctgaaggtcg gtgtcccatc tcccacaacg attaggattt tttctggatt
    39841 tctattttct ccgccattgt ctttatacaa tgtttcatag ccatttttaa gccctagtgt
    39901 aagcggagtt cctccgattg gtgtacgatt taatgctgta ttctcacttc ccgtcaaacg
    39961 attgatatca tttgtcaatg gaaagatgtc cgaactgatt tgctcatggt tattgatagc
    40021 tgtactatta tggtaaaaat tcaccatacc gattcgaata tccagactcg ggtcagagag
    40081 cagatcttta ctcatttcgt ttactgcctc aatcaacgca gcatttttag tttgactatt
    40141 ggtcccagcg gttaattcac tcatactcgc tgacttatct agaacaaaaa cgatatcgat
    40201 tggactgatt tcctttttct cgcccccgat gacatctaga tagacattgt aaagggttgt
    40261 tgcatcttca ggatgtagat cagatgctgt gctgcttggc agaacaggtt ctacccattt
    40321 tttgatgtac gccccgttat aatccaagta actgttttca aaattccgtt catttcccca
    40381 aagctgaacg gtttgagctg gaacgtttct atcttcttcg cctgcagttg atccattatt
    40441 agtagcatag tcgtaatttc gccagttcgc tcccccgttt gtataatcac tatcatcgat
    40501 caagttctct ccgtcatatg gcgagccttt gtctccttga tagcgttcat tgctttgtgt
    40561 ccaatttcct aacacttttg tatagtcatt cgttgtaaac ttcgggtagc gatgctgttc
    40621 gttttcaact tctccgctag gatagatata ttcatagggg tcttgcgtag ctgttggccc
    40681 aagacgctcc aaaataccgt tgaataactg gcgttgaatg cgctggagtg cttgaccgct
    40741 gggtacgatt ggttcgtcca gcttttccat ctcattttct tcgctacgtt gaatttcagc
    40801 ggaatcttct gtatcagttt cattttcttg taattcttgg ttatctattc tttcatcaac
    40861 caccacttga agaggtagtt acccttcgtt cacatcgggg atcttttctg tttcaaaaat
    40921 caatgtgccg gtttctgctt cttttgaata aacttttccg acataccatt cttgaccatc
    40981 gatcgtctcg acttttaggt cttctccatc ttcatcatag gaggatagac ctgttccacg
    41041 aacgtttttt acggtaccaa tcccggcggc tgccgcatcg attgctaaac gtattctacc
    41101 ttcattggca ctttcctttt tttcaaaagc cagatgccat tcaagggttt cttctttttc
    41161 aatatacttc ccttcaattt ttgcatagtc ctcatctaag aatacctcat cctcctttgt
    41221 ttctgttgac tcagcagcta catccagggt cgtcatatga tagactgact ggaaatatgg
    41281 tccaaatagc aaactgacag ttactaactg caaaagcttc aattttaacc ctttcacatc
    41341 cttatactcc tttcaaaaat atttgtcttc tttcacaaca atcaacaaaa caatgcccat
    41401 ctaattataa tttaatttaa ttttaatttt aaatcaaatg atatcctttt tagttaaaaa
    41461 acaccaatta tacaacattt attattaaaa ttaaattata aaattttata acgttctcat
    41521 ttaacaaaac ttaagttatt aagacaaatg aataaacaac tacgctttcc tcgaaacaaa
    41581 aaaataaagc acaaatgcgc atttacgcac tcatgcttta ttcgtacaat taattcagat
    41641 aacggcagcg cataggatgc caataacact tcctaaaata gctcctccta aaatgtcagt
    41701 aggataatgt aaaagtaaaa aaatcctcga ataagcgatc aaacaagcaa ataaaaaggc
    41761 taatattcct gcaactggac ttaattcgaa caacgcagct actgataaaa aggctagcgc
    41821 tgtatgtcct gaaggaaaag aagaagtctt cggtttactt gtgtaaagga caagccgacg
    41881 atttttttca taaggtcttt tccgtcttgt cgtttttttg ataaaaagca aaccaacaaa
    41941 aaaatagatc aaactgccga taagaatggc tagaccatat tctctagtat caggtatcaa
    42001 gactaaaaca gcagcaagga gcaaccaaat aaaaccacca ttagagatat tactgataaa
    42061 tttcaaaaaa ttgatttttc gactatccgt tttccgttgc ttggcgaact tgttgataat
    42121 actatcatcg attttagcaa tcaaacgcaa catgttattc ctccttttta agaacctttt
    42181 cttgcgtacg atggataaaa agcaggactt gaaaataaaa caagaaactg aaacctaata
    42241 aagcaaaata gattggtcct gcaaaccaga atgcgacaag aaggatcaac gtgcctgcca
    42301 aatagaaaag cgcgcttttg aaatcattaa aaaacaagaa aaatgcagta atccaagaag
    42361 cttctttttg ttccagttga agcaagattt tgtaactaaa gagaagcgcg cttaatagaa
    42421 gcaaaaacaa cgtagtatac atcaatgtat agccaattcc cccaccccaa tagcggaaaa
    42481 tctgataatc gatcaataga agaagaaaat aaacacttgc taaactatct tgctttccat
    42541 aaagagagaa gttctcacga aactttttcc agaatagtga accgagcttt ttctcttcat
    42601 tttttttgta atgataaatc atatacagaa ctgttcgact tgcagttcct aatgtgaaaa
    42661 caggcaagac gcacaggaac catagtagct gtaaatggat aagacgtgga atccattcaa
    42721 tgatttctaa gaaataatca ttggcttttt taccaatcga tcgattcatc atccttttga
    42781 acctcctgtc aaatccatcc cttcaatgaa ataacgttgt gcaaaaaaga acagcaaaat
    42841 cgtcgggatc aagacaagtg ttgctcctgc catcagataa ttccattgtg tcgttgcttg
    42901 gttctgaaaa acttgcaagc caatctgtaa cgtgtatttt tcttgatctt ggatatataa
    42961 cagaggacct aagaaatcat tccaagctgc gttgaaggaa ttgatcgcaa tggtaatcaa
    43021 ggcaggtttc gtcaatggaa gcatcaaatg actccaaata tacaaatgat tcgctccgtc
    43081 gatttcagca gcttcgatca attcattatt gatcgataag taaaattgac gcatcagaaa
    43141 tatattgaac gcattgccga agaacgatgg aacgatcagg ggcaaataag tacctaccca
    43201 gccgatcttg gagaataata catattgagg gatcatcgtt acaaaccccg ggatcatcat
    43261 cgtagaaaga accaaagcaa acatcagctt tttcccagga aaatcaagct tcgcaaatcc
    43321 ataagcaata aaagaatttg aaaggacatt accgatcact actagcacag tgatgaataa
    43381 tgtatttctt gcatagcgcc aaaaaggaaa ggcggcaatc gtatccagat agttttccca
    43441 tacgattttt tctgggaaaa aggtcggagg ataacgaacg atttcttcca ttggtttcaa
    43501 tgaagtaaac accatccaaa gcaatggaat gatcaaaatg attcctatta ctgtcatgag
    43561 gacataactt agtatttttt ttgtttgccg attcacactg gtctttttga aataatccat
    43621 catttgccgt cacctccaga ataatagacc cacttaggtg caagcttcaa attgacaaac
    43681 gtcagaacca acacgatcag aaacaggatc attgacatag ccatcgcata acccatatca
    43741 aaagctacga acgccttgtt ccacatatgc agattataaa aaagcaaaga atttgcaggt
    43801 ccgcctgttc catttttcgt catgacataa gcttcttgaa aaatttggaa agaaccgatc
    43861 gtagaggtga tcacatcgta aaaaataata ggagtgatta atggcaaagt aatacttttg
    43921 aactttcccc aaacgcctgc tccatcgatt tctgctgatt catataaaga tctaggaaca
    43981 ttttgtaatg tagctaagta aagtagcatt gctcctccag aactccatat tttcatcaaa
    44041 atcaacgcag gtttcgtcca ttgtggatca aacagccaag ctggtccagg gatatggaac
    44101 cagcccagaa atgtgttgat caatcctgca gatggagaaa gcagctgcat ccataagatg
    44161 tagactgcta ctcctgataa gactgccggt aaatagaaag ctgtacggaa tacactgatt
    44221 cctttgattt tttgattgag tactgtggct aaaaacacac tgaaaatcgt cgtcagcggt
    44281 acattgaaga tgacgaaata aacggtgttg tataacgatt tccaaaataa atcatcgtga
    44341 acgaacattc ttttgaaatt tgctagacca atgaaattca tcttggatgt caaattataa
    44401 tcggtgaaac taccaataac tgaaaaaagc ataggcccta gcataaatac caagaacccg
    44461 ataataaaag gcgagataaa taaataggcc catcttgctt cttttttctt tcggatagat
    44521 aaacgcttca aattttcttg cctcctctgt acctagacag tcaaaaatgg attattgatt
    44581 ttgcttgact aagttttcta ctgctttttg tgcatctgcc aatccttctt ttggtgattt
    44641 tgttcctaaa agaatctggt caatctgttc attcactaat gtcgtgtaat ccggagcatc
    44701 taaaggaact ggtgtgatca ccgtattttt aaagttttcg tccgccattt gatagatcat
    44761 ttttccttta tccgttaggt tgtcattatt cactaaattc tcattggctg tcttgctcgc
    44821 catgatatca aaactttttt cgccgaattt ttcttgtact tctggagaag aaagatattt
    44881 gatgaattca taagaggcct caggatcttt tgctccgtat ggtacttcca agacgaatcc
    44941 gccaccccac gaccaatggc ctgaaccttc ttctttttct gggagctgca tcacgccaaa
    45001 atcaaaatca tccggtgcat tttccatcaa actagagtaa taattgatat tttgggcacg
    45061 catggctact aatccggaaa taaatggatc agatacacca gacccaaatt cggcttctaa
    45121 tttattgatc gtatttttcc cataataatc ttgccagtct tggatccact ccaaggcttc
    45181 cactttattt ttagtatcaa tcttgacttt ttcatctttg tcaaaccaac tagtcccgtt
    45241 atctgcgttt agcgcccata catcagcccc taaattccat aatggataaa aaccgatgcg
    45301 tgtaaattct tttccttctt ttttatctag tttacgtgct gtttcttcta attcatccca
    45361 agttgtcggt agatcttgtt cactgattcc agcttcttta aataactttt tattataaaa
    45421 aatgacttgt gtatctgtat tgaatgggat cgcataagga tcaccttcat attctactgt
    45481 atcccaaagc tgcggataaa aatccttaga agtgtctttt tctacatatt tggagagatt
    45541 agttgcttgc tgtgcttctg ctctttgggc aacggaattt atgtcctgta caataacatc
    45601 gggtgcattt ccagctgtta ttgcagataa agatttagtc cagatgtcac cccatggctg
    45661 atacttataa tttacatgga tctcgttttg tgattgattg aaatcctcaa tgatttcttc
    45721 gatagcttct tttcgtgcac cggatcccca aaaggaccag aaatcaatat tttttcttcc
    45781 atcacttgtt ttttcagaag aatttgctgc acttgaactg gcatcgcttg cattacttga
    45841 tccgcatcct cctaataaaa acaatgctga acttgccagc aaccctgtaa acaataattt
    45901 tttcatattt tacctccaaa ttttaatgta accgatgccg gttttaatat aacgatatca
    45961 ttttgttctg aaaataacaa tttataaggt atgattctaa aaaaattatt aatgatacca
    46021 atactttata taattcgcga gcgctttctt tgaatttttt aatctttcgt agcagaatga
    46081 gaatgtatta aaaatagatt aggaggaatt ttgatgttta gacaccagaa agaattgcag
    46141 tttgaagcaa aaccagatcg tccgaatcca ttaatcgcga aatatctgca ggagctgatc
    46201 ggcggccaat atggcgagat gagtgtagct atgcagtacc tgttccaagg ctggagctgc
    46261 cgaggagaag aaaaatataa agatatgctg atggacattg caacagaaga aatcggccac
    46321 gtggaaatgt tggcgacaat ggttgctcgt ttattagagg gtgcgcctgt tgaagatcaa
    46381 gaagcagcga tgcaaaaaga tccaacaatc ggtgccatta tctctggaat gaatccacag
    46441 cacgcgatcg tagctggctt aggacctcgt cctgctgaca gcgtgggcaa tccatggagc
    46501 ggtgcctata tcattgcgag tggcaacttg ttagcagact ttagagctaa tttaaatgcc
    46561 gaatcacaag gaagacttca agtagcacgt atttacgaaa tgatcgatga tcgtggcgta
    46621 aaagatatgc tgtctgttct ccttgcaaga gatagctatc atcaaaatct atgggaatgt
    46681 gcagtgaaag aattagaaga aaaagaaggt tcaatcttag tcccaagtac tttcccgcgt
    46741 gacaaagaac gaaaagacat tgcttatgac ttctataact tctcagaggg agaccaaagt
    46801 agtgaaggtt cttgggctag tggcaaagca ctggatggcg aaggcgaata tcaatggttg
    46861 aaagaaccta agatcgaagg cgctgcacca aaattagaac cagtaacacc aaaaatgtat
    46921 gggacacctc cattcaagaa ataaatatct acccgtagaa acacccgttt tttgttccac
    46981 acgctttgtg agcaaaactg actaaagtca ttaatcataa ccacccttca aaagggtggt
    47041 tttctctaga gctataagct caaatcaccg gccagcgcct aaagacgctg gctttcatat
    47101 tttatgttca agccatattg cctttgccag ttttgcccac ctcttaaaag gtttatgtac
    47161 tactccttag cccttaaaag gatcgtctta ctctcgtaca ctcagcttat ctaacgcact
    47221 atcatgtttt tcttgttctt gaatgtactt tttgatggtc gcttcatttt gtcctacttt
    47281 tgtcacatag tatccttcca cccaaaagtg tcgataccca aatttatatt ttagatttgc
    47341 acaatctctt gatgatctcc tgaatattgg ctcgatattg attataaatt atttttcttc
    47401 tatactttgg tgtgaataca atgtggtatt tacacatcta ctttgtacgg gctaaactat
    47461 ttccctttat tgctccaccc gcatagcaag tggttttgta tttcaatcgc tcggcgcgct
    47521 caattaggtc taaagacaat aaatctaaaa acccgctgct tcactgacag aaacaacggg
    47581 ttttcagaaa aaaatgaaat gaaaaagatc tcttacggca atctatttta tttttttgat
    47641 tttttataaa tggaaaatgc ttcaagaagt ccaagaaata aagccgtata aaaacaagaa
    47701 cctatgaaat ctttatttat tagatattca acagaaatcc cgataacact agccaacaat
    47761 atatttatca gaagtgtaaa ataaggatgc tttttataga atagaactag tgttgttttc
    47821 atagactctc ctttcttcat atttccaatt aatcacaaat tcacggcatt actagaaaaa
    47881 ttaaaggggc gcagaagtgg aaaaatactc ttcgactttc cctacaaacc aggccatctt
    47941 gtgtttaata actataccaa atctaaggta cctctaaatc taaattccat ttgtggcggt
    48001 gacctccaat ttttaactct tctatctccc atccagtata cataaccttg atacttcgac
    48061 cacttatata tcgaacacac aaatacctat ccattgcagg agtactacct aacttagttg
    48121 ctacttgcat ctaaataaca gctgaaaaga taggacttac tcttagtaaa gtatctgaac
    48181 tattaatttt taaactatca tttttatcct caactacatg cacatctgtt gcaacttcac
    48241 tttctgtctc atccagataa atgattaagg aatcgggaat tgcaatatct tcagctgacg
    48301 ctggaatagt tgagctaaat tagtcatcat atctttatta taaaataacc aacagcaaaa
    48361 aatacaatga aaaacaaact tggaactaat gtatcattaa taaatgttga aaaattcagc
    48421 aactcattac tgtatgattt tagcagccca accaacatat accctataaa agctaataag
    48481 atggttagga atcctttaga atttttactc attcatagac acttccttaa ataactttta
    48541 ttatagaagg tattgtaaat aataatattg acaaaaagtg actcaaaata aaaaaaacct
    48601 tacattatac tggaatgaac tgtattgata gtgtacctaa aagctctact gacataagat
    48661 cgtgtaatcg gtaaagtaat tttattaatt atacgggatg taatcaatta gagaataaac
    48721 taatcataaa aggtactttt acattcataa ttgtcgcttt gagattctac tttggttcac
    48781 tatctgaccc aattgcacat tttcgatcat tacaagtatt ggtgtcgtta gaacaactaa
    48841 ataaaaacta gcggtagatt tttcagaatc tatgctaatt tctgtatgga tgttccagtg
    48901 atggcaaatt tctcttttca ttgtttttct tgtcgcatga tatgcctttt tgtgttattc
    48961 agttaaacta tagaaattct ttcctagaca gatcttgatc ccaaatttta cgtttttgag
    49021 catcgatata gtttaaaatg acattactca tatctaaaga gtttagattt tttaggacta
    49081 aaactgtcag ttgttctttt tcttctttct gttaaagtat tgtcgcgact tttcgtatac
    49141 gttaagatat gtcgtgaaaa aacaagtttt gtgacacaaa aaaacgaatg acttgaggaa
    49201 atcacctcaa tcattcgttt aaaatgctat atattcttta gtttaagata cggaaattaa
    49261 tgccatcgac cacactagta gaatgaacga catttacttg gccttttttt aatttcgtta
    49321 tgtttagcat ataaaaatat tatagagttt acttacaatg cttaaaacat atactgtata
    49381 atctgatcaa ttttagccat gtcttgcaat ggtaagtttt ctattttttt gagttttcgt
    49441 tccttaaaat caagagattt taattgtgta ataattactt gtccttttat atctagctct
    49501 tcaggtaatg agtaacgtgt cggtaaattc tttatagtgg aagtaattgg acatatgacc
    49561 gaaaacattg ttttacggtt aaattcataa cgagagacga ctagtcctgg tcgtcttttt
    49621 tgaatttctt ttcctacgga gggatcaaaa tcaatccata caatatcacc ttttttagga
    49681 atataaattc tttcttctga cactataaaa tttctctccc ttcaggagtt aaatcttccc
    49741 attcgtcttt ctcataatac tcggcctctt ccccaccact aaatggatct tcaatttttg
    49801 gaactaacgt aattgttcca tcatcagaat acacaacgat atattcttgg ttttctgaag
    49861 gtttctttcc gttatcagaa ggtaaagtta ccactacaga acttccttgt aatctagatt
    49921 ttgtaacaag cattatcatc actcccttaa taaaagtata ctatataaca ctaagtaacg
    49981 caaaattccc ctttgtaaac tatctagaaa attgttttgt ttaaagtata tcttattgga
    50041 tataaataga aataaattgt agccagttca ttttttcttt aactaaaaaa ataatccaag
    50101 aaacattgaa cctatggatc caaaagctac ccaaatacta tagctaaccc cccgctacct
    50161 tcaattttgc agataaaacg ctttgggaga aaatttcaaa gacaacaggc catcctatca
    50221 tgcccgatta taaacaaaaa gctggctatt ccttttgctc tgacaaattt caattgggaa
    50281 agttcacgaa actagcaggt gaagaagttt caactgttcg gatcaaagaa tgcccgcttc
    50341 aaatagaaac attggttcaa cgaatttcaa ctagacaaga ctttgctatt gtagaacgtg
    50401 agatcgtagc tatttttgta gaagaaggga ttttacatga tccaactcat atcaatgtgg
    50461 ataaatggca acctcttatc tataaattca gagaatatac aactgccaac cagtcgttaa
    50521 ctttgaattt tagattccaa gaattcaaag agtcataatg ataaacatcg ttaggtataa
    50581 ataaaaaaga ctcgcagcac gagtaaaaaa caaatagaag ctatacatta gaaaggtcga
    50641 ctgtgaccct atagatgcag tatatgcagc ttatgagcat ttcttctgtt ctctttgttt
    50701 ttgggatctg tgctgaagtc tttttcgttt tttgccgctc tttctttgaa aaatcgatta
    50761 tgttatacct tctccattac taattcaggc atctgctgag taatgatttt tcgcgcaaaa
    50821 gaaatatctg ttacccaagg ttcgatttgt tcttcagtca agacaagcgg cattcggtca
    50881 tggattggtg cgactgtgcg gttaggttca gtagtcatta tgattgattc tgccattttt
    50941 tcatcctgat ggctacgata aaaaccgcca atatacacta ttttttcctt atttgaaaac
    51001 ataaatttgt ctttttcttc attccactca ttgggaaaac acaacgattt tgcaaaaatg
    51061 gttgatgaaa ggtctttttt tcttctactg tctctgcacg ggcattaatc atcaattgtc
    51121 cttttttaaa tccggtaaat ccccacttca tgatttccgg agtgaggatg ttttcttcct
    51181 cttttcttaa cgtcacaaca agatttgacg gaaaaacttc tccagctgct aattctgctg
    51241 cctgcttcgg ttgtttcgtc tgggcttctc gataataatt ctgaaggagc tctgactcta
    51301 gatcaaaaaa ataacgacca cacatcctaa tccctcccaa tctttttttc tatcatacac
    51361 tgcaacaaga agttcgcacc aacaaaacgc tttcaatttt tgtagaacta aaaaagttgt
    51421 gacaagtgac aaactctcca gtgaatggta ttctcctgcc aactcctcgg tcacaagtca
    51481 caatattcaa caaacatgag aagctgcttt ttgaaattgt tccttgtgac tcggagtgaa
    51541 acggcaggct tacgacctct gggtaaacgg tgttcaaaag ccagtttctc ggtattaagc
    51601 caaatttatg caaaaatgta gaaagctatt ttcacaaaat ttttcttaat actcgaaact
    51661 aagcgacttt ttcacaacct cttccttaaa cggtgttcaa aagcttgcat ctgcggtaat
    51721 aagcccaacc aaacgaaaaa tatgagcagc tatttttatt tggctgttct tattacttga
    51781 tgcagggcag ctttttcaca acctctccac taaacggtgt tcaatcagct aaccttcggt
    51841 attagctcaa aaaacggcaa aatatgagga actattttgc cgtttgtttc tctaatactc
    51901 aggtcaaagc gctgatttca caacctctaa tacacggtgt tccagaagta gcttcttcga
    51961 aaaataagcc gaaatttcac aaaaatttga gaagcaattt tcgtaaattc cttcttattt
    52021 cttgaagctg accacttctg tcacaacctc taattattaa agaacctttt gcgaagttaa
    52081 caatctttct ttgatcaatt gaaaattctg cctaagtagt gatagatcct gtgtgacttt
    52141 caacaataag atacttccct ggatttcagc aatcaacgct ttggcttgac ggtctgcttc
    52201 ttcatcggac agtttttctt cagaaagtgc caggatattt tgtttcgtat acttgaccca
    52261 ttgattgact aattctagta gcaacagacg gtattcttca tccactgtac tcaactcaat
    52321 aatcaaatta cctacaggac agccatgata agtgatctgt gtctcatgat cagcgaaaat
    52381 ccagtccaac atttcttcta atgcttcttc tggctgtttt ccagcattta agatgtcttc
    52441 gaacaattct gtctgccata cgtccatatg cgcatggatc accgctagac aaacttcttt
    52501 ttttgaagaa aagtaataat aaaattgacc ttttcctgta tcagaagctg ctagaatatc
    52561 tcggattgac gtttcatgat agcctttttt ataaataaga tctttggtcg cttccaagat
    52621 cttttccttt gttttcaatg atattctcct ttttcatttc tcatagtcct atattataca
    52681 gtaaattcat cattttttct tcttaatcgt ttaaaaaaga ctgtgccaaa ttatctgaca
    52741 cagccctcac tataaaactg ttctcatata gctagatgtt cattgattca agaactgcga
    52801 ggacaaaagc aattcctatc ttatgatagt tgctctaata cttcctctgt tgtcatcact
    52861 tgatctgcaa taaagccaaa gttcgtcaac gctgcatcca ttgcttcttg gccaggagca
    52921 ccaattgcat ctgtcgctac cacaacattg aatccactct ctaccaattc acgcatatgg
    52981 gaatcgctac acaagtttcc gttcattcca ccaagaatta ctgtgtcgat tccatttttt
    53041 ctcaattgga gcgccaaatc attgctttct ggtccaaaga ttttatgagg agagctgatg
    53101 atcgtatttt catccaaata aggtttcaat tcttcgataa aatcggctcc tgaaccttct
    53161 tccactgatt catattgact ttttctagca aacatctgct gctcaagcat catatgttct
    53221 cctgcaccgc caaattgcca tttatggtca tgtgggtaaa aataatgagg agaaataaag
    53281 agtttgtatc ctttttcttt tgcttgtttt accatttcaa tcatattttc gatcgtattg
    53341 tatttttcta agatatcttt tgtcaaacca aagccaccgc ctgctggttt caagaactcg
    53401 acttgcgggt cagtgagaac tactgctgta tttttattat tgaacatggt ggattctcca
    53461 ttcgttattt attttaatac atcatttaga gcttcactca ttgtcggatg agaatagatt
    53521 tgatctctca ataacgtata aggaagtttt ccattcatag ctagcgaaat caagttgatg
    53581 acttcatgag aatcttccgc atagatactt gcccctagaa tcaagtcagt ttcagggtcg
    53641 actaaaactt tgaatacacc tttaggatct tctaatactt gtgctttagg gacaccgctt
    53701 gtcatatact tgaataattt gtaattgacg ccttgtgctt tggcttgttt ttctgttaaa
    53761 cctacattgg ataaagtcgg agtgataaat acactgtaag gcacagcttt ccggttattc
    53821 gttgttcgtt tattctcgcc cttcaactga tccataatga ttcgataatc atctagagag
    53881 atataagtga actgcaatcc gcctttgacg tctccaatcg cccaaatgtt gtctgcatct
    53941 gtacgaaggt attcatccac agcgattgct ccgcgatctg ttagtttaac atctgtattt
    54001 tctaatccaa gtgatgctgt acttggtttt cttccagttg cagccaaaac ttttgacgct
    54061 tggattgtta cttcttggcc atcttctgta aaggtgacgg cagctgttga ttcttggtct
    54121 gctacttgat ctacagatac acctagatgg aattcgattc ccgcatttgt catgtcttct
    54181 aaaatcattt gcgcgatatc ttcatcttca cgtggaagaa attcagaatg ggcatcaaga
    54241 acgacaactt tagatccgta ttcattgaac attgatgcaa attccaagcc aatatatcca
    54301 gccccgatga tcactaattt ttccggtaat tgttcctgat ccatcgcttg cgtagaatca
    54361 atcaagtagc gacttgtatt caatcctttg attggtaaaa tgattggttc agaaccagta
    54421 ttgatgaaaa tccgttcgcc ttcaacaatc actttttcac cattattcgt cacttcgatt
    54481 tgatggttag aaagaaaacg tgctgtaccg tccatcactg tcccagttgc ctcatcgctg
    54541 atcatatgat aatttttggc gcgaagcatg cccgtcaatt tttctttccg agcaacagcc
    54601 tctgtaaagt cgattcctct ttctccattg aaaatcaatg atttagaagg aatacagccg
    54661 atgttgatac atgttccgcc atacatacgt gttgactttt caacgactaa aaccgattca
    54721 ccttttgaag ctaacgcctt cgctaaagtc ttaccgccct ttccaaaacc gatcacaata
    54781 ttttgatatt tttccatcat ttttccctcg cttctttttt acctaccgat tggtacaaaa
    54841 atatgataac cgataattgt ctattctcca aatcatctgc tttatttgtc aaaaaaaacc
    54901 agacaaaaag cggtcctttc acgtttttag tctggttcga tttcctttat tcttctaaac
    54961 aatcgttact tctacatcga tatttcctct agttgctttg gagtaagggc agaattcatg
    55021 cgcatcttct gcaatttttt gggcttcttc ttcgctgatg ccatcgatat gcacttctaa
    55081 tactacaccg atctgatagc cgccatcatc taaattataa agagagacac gtgcttttac
    55141 tgtggactct gctgtcattc ctgcttcttt gatcatatgt tgtaccgccc cattgaaaca
    55201 agaagcataa cctgctgcaa ataattgttc tggatttgtt ccttctgcat ggattcctgg
    55261 aggagtgatt ttcatatgca tcgagccatt tggtgcctcg acttctccat tgcgcccgcc
    55321 atggttgatc attgctgttt cgtatgcttt tttcattgta ctgctccttt cgattgacca
    55381 tttgctactt ggctataatt atagtgtatg acaagtaagg cgctttctac aaaaattctg
    55441 cttattcgaa taccagaatg ccgtcttcta ctatttttcc aaaaaacaaa aaaatactac
    55501 tcgtgaacaa cagcgtcata tttgttccaa aataaatagc aatcttttct acataatctt
    55561 ttatatgatt gattttaaga tacatatata ccagaaagtt gaccccataa accaatactg
    55621 ttaaaaaaat aaccatattc gttaccattt tttcctcctt ttgctggtct ccctaccagc
    55681 actcgattta accataccac tttttttgcc gtccaagcaa ctagcctttc aaaaagactg
    55741 gtttattctg ctgttaatga ttcaagatca gaaaaatgtc cgaataattt tgctaatttt
    55801 actaacgcca acttgttctt tccgaattca tcattttcta tctgtaatac tagtaacggc
    55861 tcatgtaagc ttaaacggat caaaaaccag ccgtttccgt atggctcttc tagatcatat
    55921 cgaatacctt cttcattttc cgggtcgaag ttcatccctt tttcttcttc caacagtcgc
    55981 ttcatttctt ctaatatctt gtttccttgt tcgcgtggtt catcgctgaa caattttaat
    56041 cggatttctt gtacttctac gggctgtttc aactctttga tttgttcatc taatgtgata
    56101 ccttttcttt ttaattctgg caaaagcatc aggatctttg cgatgacata tgcaccatca
    56161 tccagaaaat agttttcctt gaatgcagcg tgtccgcttg tttcgatggc tagctgtgta
    56221 tctttcccaa gacggttaag ttctaatgct ttattgatta catttcgata gccggaaata
    56281 taacgaactt ggatgcctcc tttttcttca atgaatcttt gtagatgaga agaagtaggg
    56341 gaattcgtca cgattcttgt tcctggatgc tcttttaata cgattgtact taatactgcg
    56401 atcaaattat ttcgattgat cactgttcca gaagcactga caactgcaga acgatccaca
    56461 tctgtatcga aaatgatccc aagatctgct tcatttgcta aaacagcctg cttgatactt
    56521 tccatcgctt ctttattatc aggatttggg atatgattag gaaatcggcc atctggttcc
    56581 aaaaattggg aacctgttga atccgcacct aagctattca atactttttc agcaaagaat
    56641 ccaccagcac catttccggc atcaacaatg attttccaac catttagtgg tttgctttct
    56701 agtgttccaa tccccttttt aatttttgtg actaaatctt gcgcataagg tgtcaaaagg
    56761 tctgcttttt ctacgcttcc agtttgttcg ctttttattt tttgctgctg tgataggata
    56821 aaagcaatat cttctttttc tgctcctcct tctgaggtaa agaattttat tccattataa
    56881 taatagggaa gatggctagc agtcagcata accgcagcat cgcacgagaa ctgttcaaat
    56941 tgagtggaca taaacatagc aggcgtagta gctaattcga aatcgatgac atgtatccct
    57001 tgttctttca gactttggat caacgcctct ttcagtgctg gtccgcttat cctactgtca
    57061 tgaccaatcc caatcgtcca ttttttattt ggatcggttg atttcttctt tttctttatc
    57121 cagtttgcta gtccccagcc gatctttttt accatgtctg tcgtcaagtt tacttcatat
    57181 ccttcaactg gtaatgcgat tcctcgaata tccgatccat tttgcagcgc tttcatatct
    57241 ttcatataaa agtcctcctc atttattccc tcattttttc cagcttttct gcaaatcgct
    57301 gtgcttcttc ttctgagcgg caaataataa tgaatgtatc tacaccggcc atcgttccga
    57361 caacttcagg gtaagccact tcatctagcc aattcgttac cacatcggca ccatttcgtt
    57421 cagtcaatac gataaccatg aactgaacag actggatacg caaaacctcg cgtctaattg
    57481 ctgtacgcaa acgttcttca tttaaagaaa cagatggctg gttaaataat gtatagcgta
    57541 ctattttgtt ttcattttga ctttttacta acttcatttc tcgaatgtct cgagaaatcg
    57601 ttgcttgagt cacatcggcg cctgcttcat gcagccgcgc aagcagctct tcctgtgtcc
    57661 caataggttg ttctgtaatg atctggcgga tcagtgcttg tcgctgtttc tttttcatat
    57721 tagacacctc tcaatgttga ttatagcaaa agataagtaa tatttcttca tattttggta
    57781 ttttttactt ttattttttg ttttcattca ggttgctaac ctttttctat tttaacacgc
    57841 aaaatcgtct tcattttttc aggtgctgat tttcttggat cgctgatgta aatctctttg
    57901 tgttctttag aagctctttc atagccttct tttgcgatga atgcttctaa tttctcaaac
    57961 gttgctggtt cttcggcata gggcccgacg tgtaagattt gggcacaaag accttcttcc
    58021 atctttttga atactacttg ttctttcaag tcttccggaa gtttgctaga acgctgaatg
    58081 gcttcttgtg ctatcgcttc tgtaacaaag tcaggctgtc ggatcatcaa ttgataagaa
    58141 aaatgttctt ttttcatcac tggttcatgc aaatactttt cttgcagtcc ccattgtcct
    58201 tccagtggat agacagtata catctgataa tcaggaatca gccaattttt tttaggcgac
    58261 atgcgtattg catagctgac tgcatataga caggctactc ttcgtttaaa gtcttcctga
    58321 ttcgggtcgc cgatccctct gatgctaaag aatgattttt taggaacctc tagtatttgc
    58381 gggctttttt tcatactata gctcttgtct ttacgccatt caattttttc catttttctt
    58441 cctccgcgaa attccattta gttatttatt atcatacctc tttttgagtg acttggctaa
    58501 tcgtgttgac actatttttc agtttgtgct agaataagtg aagtaaataa atcgtacaga
    58561 taacacgttt cggcgtgtcg agagagaggc ggtttctatt tttataatag aaatcactct
    58621 ctttttttac gaaatttttt agaggtgatg taaatgacaa aacaaaaaca gctgctttta
    58681 gtacctgcag taattgcaac agggatgatg tcttttgcgg gcgtattgat cgagacggcc
    58741 atgaatgtaa ctttcccaac tcttatcaga cagtttgatt taacgactgc acaagtccaa
    58801 tgggtaacaa cgatttatct tttgatgatt tcgatcattg ttccgctgtc tacttatttg
    58861 aatcgcaatt ttagtctcaa aaaactcttt ttagcttcaa atctgctttt cttggcaggt
    58921 ataatgatcg atttcttctc tcctaccttc atggtcctat tgtttggtcg attgctccaa
    58981 ggtgcagcga caggtatcgc tcttccgttg atgttccata ttatcttgac atttgccccc
    59041 ctcaatcgac gaggcgcgat gatgggtgtc ggtactttga caacggccat tgctccagca
    59101 attggcccca cttatggagg cattatgact tcacatttta catggaatca tatcttcctg
    59161 tttcttgtgc ccgttttgtt tctttctttg attatcggct ggtttgctat tcccgagatg
    59221 gcagtacaaa aaagtggtta tttggattgg ataagcgttt taggaatttg tcttttgttt
    59281 agtggaagtc taacattttt gagtacgttg ggaacagttt ccagctggat tgctttaatc
    59341 atcggcggta ttggctggtt ccttttttac tatcgaagta aaaaagtgga gcatccactg
    59401 atccgactgt ctattctttc aaataaaaca ttccgcttgt ttttgattgg cttcttagtt
    59461 tatcagtttt tattacttgg tgtatctttt gtcttgccga atttccttca gatcgttcaa
    59521 ggaagtagtc cttttgtcgc tggattagcg atgcttcccg gcgcagcggt tggtgctttg
    59581 ctttctcctt tttccgggaa aatgctggat caatatggtc cgaagaagcc aatttttgct
    59641 gggctgattc tttctttgat tggttggcta gcattattcc tactcatagg acacgcttca
    59701 gtgggtgtat tgattgcttg tcatgtgttt tatatgatcg gtatcggatt atcttacagc
    59761 aatatgatga ccaccggaat gaatgcactg aatgaagaac tacaaggaga cgggaacgca
    59821 atgttcaata ccttgcagca gttttctggc gctgtggcta cttcattagt agcggtcatt
    59881 atcaattacg tccagcatca tacttcccat aactatgaag tgtctactac attaggatca
    59941 aaagcagcat taggcgtctt gttgctgttg cttctcgtaa gctttgctcg attcgcctat
    60001 tatctgttct ttgctaaaaa agcgtagatt ccatatacgg caggtgttgc atctgccgtt
    60061 tttttgtgtg aaaatggttg tttgtaaaag gaggcttttt tatggaaaaa attgccatta
    60121 tcggtggcgg gatcattggt atgaccctag ccagttactt agatacatca aaattcaatg
    60181 ttgctttatt tgatgaaggg acaggacagg caactaaagc tagcgctggg attatctccc
    60241 cttggttgtc gaaacgcaga aacaaacaat ggtatcgtct ggctaaagac ggcgctgctt
    60301 ttttccctaa acttataaaa gatttccaac ttgatcaaac gatttacgca caatcaggga
    60361 cacttttgct tcgacctgaa aaagatttag ctgaattggc tgttcttgcc gagaaacgaa
    60421 aagaagaagc gccagaaatt ggaaacatcg aatggctttc acctgaacag acatctcaag
    60481 cacttccgtt attgaaacca gcagtttcac tgcgtatcag tggtggtggt cgtctggatg
    60541 gaaaagcata tttagaacat cttggtcagc gtttagcaca aaaacaaatg gagcagatcc
    60601 aggcaaaagt cactttgcat aagaagagcg attcttggct catcaaggga ccgtttggag
    60661 aatacacagc tgatcgtgta attttgacac ctggcccggc acttaagcct ttattacaag
    60721 aattaggcta tgctgcagat atacgtccgc aaaaagggca gctcttagca tttcagacat
    60781 cttataagat gagtcaagac tggcctgttg ctatgcttga cggagaagct gatttcattc
    60841 ctttcatgga tggaaagatc cttttaggtg ctacccatga aaacgatcaa ggctgggatt
    60901 tggctcctac tagcgaagct tataagggat tgactaagag tacagaacag ttcttgactg
    60961 atccagatca gataaaaaac tggccatacg agttccgtgt aggtacccgt gcttatacgt
    61021 cagatttttc cccatttttc ggcgtactgc cagatgatcc aagcttactg gctgctagcg
    61081 gtctaggctc ttctggcttg accacaggtc cttatatcgg ctatctatta gccaacttct
    61141 taaatactgg tcattggcct acggaagatt atcaaaagga catctccacc tatattacga
    61201 aaaatccatc atagaaaaac agctttttca agtaaggatc ccgagcgata ttgcgcatgg
    61261 attacttctt gaaaaagctg ttattttagt tcaatttctg aatcaaattc tccaaacttt
    61321 cttttgcttc atctggcaag agatcttttc ctatctgagc ttcaatgaat cgtaaacgaa
    61381 tatcaagtcg ttgtttcacc agatttttat aggacgtatc ctcaaaagaa acaggaaaat
    61441 ctggtatagg taaatagtgg atgtcttcaa atggaccaaa cgacttgaat tctgccgttt
    61501 gttgcacgat tctttcaacg attgacaatg tcgtttcagg tttgattttt ttatcatcga
    61561 aatatccagt attcaggaca tagcaggctg tttgctgttt caaaaacaac tctcgaaaag
    61621 cttgatagtc ttccctaaga ggatagacac ggaaaggatt agcaaatggt tcaatgacta
    61681 gctcatctag ctgtcttttt gtagtgatat tttccgcgtc tgatcgtttt gttgctaatg
    61741 ttgcaccaaa agacgctgct aaaactgggt cattgatctt gataattggc ggaagcgaat
    61801 catctttcat gatccaaaaa acagcatcga tcttttcgct aagatgatcg actcggtcgg
    61861 gtgtcgcata acgtgatttg actgtccgcc catttccgtt tcgtatatct cctgttacta
    61921 ggactttttc tcctttactt gtacatgtca cgcccacatt ctgacaagta aggaaagaag
    61981 aaatggccgg atcatcagac ggatagtctt gtgttttatc aaagtaagaa ggttccaagg
    62041 cagtagcaaa accatttttt cgagaaataa cgaaagcatc gtcatgcaag atcgaaacag
    62101 agtgaccttc cgtatgtttt gctaaggtaa tcgttgattt tccagaaccg gacaacccaa
    62161 atacagccat cgtataggtc tggtcattac tagcatattg tttcatccca ccgtggcagg
    62221 caataaagcc attgcgattt cccaatgccc aagcaagcgt caaagtcgct ttttttaatt
    62281 ctccaaagta acgtaatcct agcacagccg ctgtattatg gagagcatca aacaaaatga
    62341 gtccatttgg aaatgtttca tgtgtccatt cgggatcaca aaagatataa agatctccct
    62401 catcaaagga aacagacttt tgataagtct ctaagatctt cgaattcgct ggctgaaaat
    62461 tcagcaaata agaatacaaa ttgttctcaa atccttctgg aatcagcaaa tgactttgca
    62521 cagaaaattc ttcagatagg ccaacgatta cttttgtatg gtaaaactgg cgcttgcgac
    62581 tttgatacac agcttctctt aaaattttct cgtatttgct ttgttccttg tctaagtcct
    62641 caaagatccg ccgagcactt gctgttcttc ccacaatgct tccatcattg aatactagtg
    62701 tcctaacatc agctggtaaa tctagttctt cagcatgtga gattgttaaa tctgtgatga
    62761 tcgttcctgg actccctttt gctagttgat aagctgtctt cctatcaaaa acttcatgaa
    62821 cattattacc gtaaaatgtc gtttctacaa tcgatcgaat actggataac agtggatttc
    62881 cacttgtgat ttcgtttaat tcgagactct cttttgtact catggctcct cctcattccc
    62941 taaacaaaaa aacgttttct ttattataca ttattcgagt ttttatttgt actgctgcgc
    63001 tgtgggaagc aaacgagtta tttttcacac aaaaaaaccg agaacttgaa taaacaagtt
    63061 tctcggtttc atcattttcc ttttatcggc ttagtaccag ccgtttgcta accagaatgt
    63121 tttagcagca tcccatgaac cataacgaga tgttacatat tgttctgcta cacgttcttg
    63181 attggcagct gaatagtcgc cgtttaagta tgaagcatct aattgataac ggccgatgta
    63241 acgtccgtta gtagctgtgt atgaaccgcc tgattctttt tgtgcgatcc attcttttgc
    63301 agagcttgaa gttggcgctg ttgcagcagc tggggcagca ggagctactt caactgtttc
    63361 aacaggtgca acgtatgtat gttcttgcgt tgctgtttca gttgtagatg ctgtattttc
    63421 tgttgttttg ttttctgttg ttgctgaaga atcatttgaa gttgggattg ttaattgttc
    63481 accaacataa atgcggttga tgtttgcgat cgaatttttt tcagcaattg catcgatcat
    63541 tgagttgtct cctgcaaatt tttgtgagat cttagataat gaatcacctg attttactgt
    63601 ataaacttca tcagcgtgag catttgtagt tcctacaaac attgcagtag caccagcagc
    63661 aaaagttgta cctaaaacaa ttttcttaaa tgaattcata ttaaactcct ttttttctcc
    63721 gttttttatt ctttcgacgc tattaacttt atcatttaga aatatttcat aggtaaaaga
    63781 aacatgacat ttaatgacaa aataacgaat tatttaat
//
LOCUS       DACGEU010000005        63487 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.005, whole genome shotgun sequence.
ACCESSION   DACGEU010000005 DACGEU010000000
VERSION     DACGEU010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 63487)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 63487)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..63487
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.005"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(451..1761)
                     /locus_tag="IXR40_000299"
     CDS             complement(451..1761)
                     /locus_tag="IXR40_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HAQ4360176.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     IDFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1773..3191)
                     /locus_tag="IXR40_000300"
     CDS             complement(1773..3191)
                     /locus_tag="IXR40_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAQ4360177.1"
                     /translation="MLSQNAVTANTIKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            complement(3431..4999)
                     /locus_tag="IXR40_000301"
     CDS             complement(3431..4999)
                     /locus_tag="IXR40_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HAQ4360178.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(5003..5413)
                     /locus_tag="IXR40_000302"
     CDS             complement(5003..5413)
                     /locus_tag="IXR40_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HAQ4360179.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAVALFLTAKGKYLTTATGLYFITGF
                     ILLIGTQFIAFPFAFFYFAAGAFSLYRVRMRKGA"
     gene            complement(5410..6333)
                     /locus_tag="IXR40_000303"
     CDS             complement(5410..6333)
                     /locus_tag="IXR40_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pectin esterase"
                     /protein_id="HAQ4360180.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(6330..7208)
                     /locus_tag="IXR40_000304"
     CDS             complement(6330..7208)
                     /locus_tag="IXR40_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HAQ4360181.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPPVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIEILLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(7195..8532)
                     /locus_tag="IXR40_000305"
     CDS             complement(7195..8532)
                     /locus_tag="IXR40_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HAQ4360182.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTPAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(8535..9638)
                     /locus_tag="IXR40_000306"
     CDS             complement(8535..9638)
                     /locus_tag="IXR40_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 88"
                     /protein_id="HAQ4360183.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9712..11220)
                     /locus_tag="IXR40_000307"
     CDS             complement(9712..11220)
                     /locus_tag="IXR40_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAQ4360184.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(11186..11878)
                     /locus_tag="IXR40_000308"
     CDS             complement(11186..11878)
                     /locus_tag="IXR40_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HAQ4360185.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(11900..12874)
                     /locus_tag="IXR40_000309"
     CDS             complement(11900..12874)
                     /locus_tag="IXR40_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAQ4360186.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            13174..14046
                     /locus_tag="IXR40_000310"
     CDS             13174..14046
                     /locus_tag="IXR40_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAQ4360187.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(14504..16702)
                     /locus_tag="IXR40_000311"
     CDS             complement(14504..16702)
                     /locus_tag="IXR40_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4360188.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLDGKWGVINGSLSQLTEEEVEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLLSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            16934..17926
                     /locus_tag="IXR40_000312"
     CDS             16934..17926
                     /locus_tag="IXR40_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAQ4360189.1"
                     /translation="MVTIKDIAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNPAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            17986..19407
                     /locus_tag="IXR40_000313"
     CDS             17986..19407
                     /locus_tag="IXR40_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HAQ4360190.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSFPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            19400..20899
                     /locus_tag="IXR40_000314"
     CDS             19400..20899
                     /locus_tag="IXR40_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009224330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HAQ4360191.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            20938..22332
                     /gene="uxaC"
                     /locus_tag="IXR40_000315"
     CDS             20938..22332
                     /gene="uxaC"
                     /locus_tag="IXR40_000315"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HAQ4360192.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYRTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
     gene            22491..23174
                     /locus_tag="IXR40_000316"
     CDS             22491..23174
                     /locus_tag="IXR40_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HAQ4360193.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLIPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
     gene            23176..24012
                     /locus_tag="IXR40_000317"
     CDS             23176..24012
                     /locus_tag="IXR40_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HAQ4360194.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            24023..25777
                     /locus_tag="IXR40_000318"
     CDS             24023..25777
                     /locus_tag="IXR40_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4360195.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLIFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQRISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(26053..26394)
                     /locus_tag="IXR40_000319"
     CDS             complement(26053..26394)
                     /locus_tag="IXR40_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HAQ4360196.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(26462..28633)
                     /locus_tag="IXR40_000320"
     CDS             complement(26462..28633)
                     /locus_tag="IXR40_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HAQ4360197.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPTVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            28844..29701
                     /locus_tag="IXR40_000321"
     CDS             28844..29701
                     /locus_tag="IXR40_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HAQ4360198.1"
                     /translation="MKITITLPMNHPETTIRDLLEKEWLVPRKVRHFLRIRKNVWINQ
                     QPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDEHLIIVDKPAGMKTH
                     PNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKNPFVLPILGRMLEQK
                     MIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSALTHVTVNKVLSEQT
                     QVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHALELHMIHPFTQEKIV
                     GKALPGLWE"
     gene            complement(29772..30629)
                     /locus_tag="IXR40_000322"
     CDS             complement(29772..30629)
                     /locus_tag="IXR40_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAQ4360199.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(30614..33316)
                     /locus_tag="IXR40_000323"
     CDS             complement(30614..33316)
                     /locus_tag="IXR40_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HAQ4360200.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            complement(33329..34618)
                     /locus_tag="IXR40_000324"
     CDS             complement(33329..34618)
                     /locus_tag="IXR40_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HAQ4360201.1"
                     /translation="MAYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDTCRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            34768..35814
                     /locus_tag="IXR40_000325"
     CDS             34768..35814
                     /locus_tag="IXR40_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAQ4360202.1"
                     /translation="MNQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            35816..37969
                     /locus_tag="IXR40_000326"
     CDS             35816..37969
                     /locus_tag="IXR40_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HAQ4360203.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDKEYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(38442..39893)
                     /locus_tag="IXR40_000327"
     CDS             complement(38442..39893)
                     /locus_tag="IXR40_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4360204.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(39890..41614)
                     /locus_tag="IXR40_000328"
     CDS             complement(39890..41614)
                     /locus_tag="IXR40_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAQ4360205.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            complement(41607..42221)
                     /locus_tag="IXR40_000329"
     CDS             complement(41607..42221)
                     /locus_tag="IXR40_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HAQ4360206.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            complement(42566..44023)
                     /locus_tag="IXR40_000330"
     CDS             complement(42566..44023)
                     /locus_tag="IXR40_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAQ4360207.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            complement(44064..44984)
                     /locus_tag="IXR40_000331"
     CDS             complement(44064..44984)
                     /locus_tag="IXR40_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAQ4360208.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            complement(44996..45943)
                     /locus_tag="IXR40_000332"
     CDS             complement(44996..45943)
                     /locus_tag="IXR40_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAQ4360209.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            complement(46422..47141)
                     /locus_tag="IXR40_000333"
     CDS             complement(46422..47141)
                     /locus_tag="IXR40_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HAQ4360210.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            complement(47190..48836)
                     /locus_tag="IXR40_000334"
     CDS             complement(47190..48836)
                     /locus_tag="IXR40_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAQ4360211.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYLQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            49015..49605
                     /locus_tag="IXR40_000335"
     CDS             49015..49605
                     /locus_tag="IXR40_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAQ4360212.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            49697..51202
                     /locus_tag="IXR40_000336"
     CDS             49697..51202
                     /locus_tag="IXR40_000336"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HAQ4360213.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLKFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(51286..52638)
                     /gene="celB"
                     /locus_tag="IXR40_000337"
     CDS             complement(51286..52638)
                     /gene="celB"
                     /locus_tag="IXR40_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HAQ4360214.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(52638..53156)
                     /locus_tag="IXR40_000338"
     CDS             complement(52638..53156)
                     /locus_tag="IXR40_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360215.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            complement(53172..53498)
                     /locus_tag="IXR40_000339"
     CDS             complement(53172..53498)
                     /locus_tag="IXR40_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HAQ4360216.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            complement(53511..55490)
                     /locus_tag="IXR40_000340"
     CDS             complement(53511..55490)
                     /locus_tag="IXR40_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAQ4360217.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            complement(55511..55825)
                     /locus_tag="IXR40_000341"
     CDS             complement(55511..55825)
                     /locus_tag="IXR40_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HAQ4360218.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            55993..56286
                     /locus_tag="IXR40_000342"
     CDS             55993..56286
                     /locus_tag="IXR40_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HAQ4360219.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            complement(56364..57476)
                     /locus_tag="IXR40_000343"
     CDS             complement(56364..57476)
                     /locus_tag="IXR40_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAQ4360220.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            57629..57853
                     /locus_tag="IXR40_000344"
     CDS             57629..57853
                     /locus_tag="IXR40_000344"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360221.1"
                     /translation="MNGSIKKILRSIDKNLMITEVSYETLQKKKTLIVAAVLFPAPCV
                     CRNCGSAVVDGNRKLMVVKNKKKETIVHFE"
     gene            57863..58042
                     /locus_tag="IXR40_000345"
     CDS             57863..58042
                     /locus_tag="IXR40_000345"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360222.1"
                     /translation="MPMVIRLKKQRYTCKNCRSHWNAQSYFIRPRHSISNHVRHKITS
                     LLTEKVSLFFISKSC"
     gene            58236..58406
                     /locus_tag="IXR40_000346"
     CDS             58236..58406
                     /locus_tag="IXR40_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAQ4360223.1"
                     /translation="MPRLTNYFLSCTNPKEIEFLVTDMNATYFQLTKHVLPNAKLVID
                     RLLGFSTPFKEA"
     gene            complement(58830..62231)
                     /locus_tag="IXR40_000347"
     CDS             complement(58830..62231)
                     /locus_tag="IXR40_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAQ4360224.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTRNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGET
                     LQTGLTTGEDGKLAIDGLAPGAYQLVETQAPIGYELDATPIEFEIERSQTAVVELTKE
                     NRLTPGGVVLTKIDDQSGEILQGAVFELQNREGETLQTGLTTGEDGKLAIDGLAPGAY
                     QLVETQAPTGYELDATPIEFEIERSQTAVVELTKANRLTPGGVVLTKIDDQSGEVLQG
                     AVFELQDANGTVLQSGLTTGADGKLAIDGLAPGVYQLVETQAPTGYELDATPIEFEIE
                     RSQTAVVELTKENRLTPGGVVLTKIDDQSGEVLQGAVFELQDANGTVLQSGLTTGADG
                     KLAIDGLAPGAYQLVETQAPTGYELDATPVTFKIEKEQEVAIFLTKENRKVADSSDIR
                     GNNPTSSGNKHLPKTGETIISQFILSILGVLLVFISIKFRKKRNI"
     gene            complement(62903..63171)
                     /locus_tag="IXR40_000348"
                     /pseudo
     CDS             complement(62903..63171)
                     /locus_tag="IXR40_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
BASE COUNT        18874 a        13059 c        11042 g        20512 t
ORIGIN      
        1 ttgtcttgaa ttgaatcaag acgccctaca catttggttt gtcttacttt gttcagtttt
       61 caaaggtcta cttcatcgag agtgtttccc gattcatttt tggctgccgt agcaactttt
      121 atatcatatc agagagacaa acgattgtca actctttttt aaaagttttt ttcgatttcg
      181 tttttcgaaa tctttcagca actcatttat cataacttat cgtttgttat ttgtcaagaa
      241 cttttttgaa gtttttttcg atagaatcaa gcttcgcaag tggttctttt taacgactta
      301 gttatcttat cacgtctaaa aacatgtgtc aactcttttt tggaattttc ataaaatgtt
      361 tcaatgaagc gcgacaacgt tgtttaatat atcattaaaa aaaataaagg tcaagctaaa
      421 atattattta agcttgacct tattataatt tcaacgattg tcaaaagtat tgtttgcagc
      481 tgtgttgcca gtttctatag ataaatcaca gcttttgaaa cataagtttt gtactgcttc
      541 gattcgcccg aattcttttg cagttatttg gcaatgagaa aagcagacat cttctatagg
      601 cttttcagga aatgctacta aatcaaaagc tcgggaagga agtgagtaac ctggagaaag
      661 gcatgcctgt acgtttttga tgtgtatgtc tttgactttc gtcatttgct ttgattcagg
      721 tatttcttca gccactgctt gccaactttc tggcatttga gcaaggtcat tgctattttt
      781 tctattgtat tcattatgcc agtccattat ccaagaaaaa ggaaattgta catcaatcat
      841 attcagattt tctaccctga tattttcgat cactccccct ctttcttttg aagatttcat
      901 tcgaatacca cagtctgact gaaaaaaatc gatatcgtga atatatacgt cactaactcc
      961 agcactaact tcgctaccaa tagttacacc gtatcctgaa cggattttac atctagcaac
     1021 ctcgattctt gatgattttc gattgactct tgcaccattg ccatctctgc cagacttaat
     1081 agcaatacaa tcatcaccac aggccaaatc acattcatag acacgcacat ttgttgaaga
     1141 atcaatatca atcccatctg tacttggtcc atcattgttg cggatgatta ctttttctac
     1201 taatacatcg ttagaataag tgatttgcaa gttccaaaaa cctgatttct gaaaaatcaa
     1261 atcacgaaca acaacatgtt ctgcatgata cagtaaacaa gcgcgtggac gtttaatagc
     1321 ataatccgca atccaacgaa gtcccttttg atcgtattca gctcttgtcc cgcttttttg
     1381 atcttttccc caatacagct cccaccaatg gtctccttga ccgtcgatta ttccttttcc
     1441 ttctataaga atatctttcg ccgagagaac attcaaaatc gctgctggcc atttcatttc
     1501 tacgccggct actcgtgtat cgatttctgg aaatgcttcg atatctgttc tccccttgag
     1561 gactgcacct tcttcaaaga taagatgact cttatctttt aaaaaaaggg ctccgactaa
     1621 ataaatgcct tttggaataa atacaggtaa gtgttctttc gcaccttgat cgattgcttt
     1681 ttgcagtatt attgtatcat cttgttgagt gtcgtttgtt ttaaagttca aagcattgat
     1741 aatccctttt tttgtccgca atacgtttct ccctatcttt cattgatttt tttcaattct
     1801 tcaccaataa atacagtttt tgaacgattc agtgggtaac ctactagcaa aatgattgcg
     1861 gatacaaata agcagaatgc tggtaacaag tttgccatcg tataaatcct ttcttgtact
     1921 aaaactgatt ggatggctcc acctgttgta gacgattggt aaccaatgag tgccagcata
     1981 aatccgccta ccgctcctgc acatgcttgt cctacttttc tcgcaaaaga atttactcca
     2041 tatactgttc catcttctct taagcctgtc ttatattgat gataatcaat cacgtcagta
     2101 atgaatgccc agaccatcaa attgaataaa ccagatccta aagtagcgat aaataaaaga
     2161 atcagatata cccatgcatt tgttatatga aggaaataca tcagcaagta catacatgaa
     2221 gaagcaagta acgcaaatac gcttgcttcc tttttaccaa ataattttgt cagctttgta
     2281 gcaaatggtg ctaaaactac tactgttccg taagtaaata aaagagcaac agacattgct
     2341 tgtttattat ggaagtaatc attgaataaa taagtcatat tcgtcccagc taaaatctga
     2401 ttgatcacaa tgaaaatgtc aacaatgact aaaataatca gtgctcgatt agctaacaaa
     2461 ccttttacca actgagaagc agatactttt tcgtttttga caactcttac tctttcagta
     2521 gtcaatttac aagttaacat atatgcgaca aatgctattg cagcacatcc gattgaaatc
     2581 caaaagaaat gattccctga aacgacttgt tgtccactct tgttatgggt atacattaaa
     2641 atcggaatga agaatcctgt agttgatccg ccaatcgcag aaccaatgct tcggaacgtg
     2701 gacaacgagg tgcggtcatt aggatttgag ctaattgctg ctgccattgc tccatacggg
     2761 atattgattg ttgagagaaa aatcccataa acaatgtatg aaacaaaaat ataagcaatc
     2821 ttcaccgtca ttggaagatg ttggacgaat ggcaaaaaca aaatgacagt cactaagcaa
     2881 aatggatact tcatttttct gatccaagga ataaatcggc cagtttctgt taactctgag
     2941 acatcacata atcttccaac catcacatca gcaaacgcat ccaaaattct cgaaatcaag
     3001 aataacgtac ctacgattgc ccctgaaacg ccaagaacat tcgtataata aatcatcaag
     3061 aaactattga ctaaacctaa aataaaacag ttacctagat caccgaacat gtagcctatc
     3121 ttatcggaaa tcccaaattc ctttttttct ttttttattg tatttgctgt aacagcattt
     3181 tgtgaaagca tttgaattcc tcctacctct tctagtaaac gttttcaaaa ttataactct
     3241 ttttttcttg tttttatatt cacaatgttg gctttttatt gcattatctt gacagataaa
     3301 aaacaaaaaa taatctaaaa acattgatgc ataagattga taactttttt tacataacaa
     3361 tatatacaaa caaaaaaatt cactaactag tgaaaataag ttagtgaacc tcatttatta
     3421 aagaattaaa ttacagatga tcttttccat catacttgaa aaactcaaaa tcagcataac
     3481 ttcctctttt tttatttaga tcatgcactg ctatcccgat aaaatttcca gtaaaccctc
     3541 ctgagagtat acacatgttt ttttgcggac ctactttctt ccattcttca gttgatacgt
     3601 ctttcaaatg aaactgtgct gtctctttct ttacagtgac tttcaaaaaa gtcttctttt
     3661 ctgtgagtgg aatcgtccaa tcttctattt gtgctactcc gttttctgat tctatcatac
     3721 gtaggcattt tcccttgtcc tcattccaag taacataaca ataaatataa ttggattcat
     3781 ttaagtacag taccagtcca gccatctgat taaaattatt aggcatgtat tcaaatgctg
     3841 tctccgcatc aaaagtaaaa tccgtttgcc gaatagctaa caaatgatgt tcgaaggtag
     3901 attgaagaga ttcaccggaa atcagacgta aaaaacctgg tctacatttt gtatcacacc
     3961 aatcagcatt tggcaaaatg cgtctggcat tccagttctt ctttagctct ccttcaaatg
     4021 tatccataaa ctgatgatct ttttcttgtt gtacctcttc atttgtctca atcattattt
     4081 cttccatcgg agttgtctgg ctatctttaa gtcttaacca atcgtcggac gtccaataca
     4141 cttcttgaat agcggtttct cttcccaaaa tagccgcacc gtttaatggt ctggtacaaa
     4201 gatatgtcat gtaccatctt cctgacgggg tttgtactaa gctcccatgt cctgtacatt
     4261 gcaatgtaga agcaggtttg tcactagctg tcagcatagg aaaaccagga tcaagctcgt
     4321 aaggaccagt aatattcttt gctcggcaaa ctgtaactga atgtcctctt cctgtaccgc
     4381 cttctgccgt catcaaataa taatacccgt tacgaaaata caaatgtggt gcctccgttt
     4441 tcgctaattc tgtacctgca aatattttat agatgggacc atcaagcttc ttcttctctg
     4501 catcatattc ttgtaatacg ataccgctgg atttattcgg tgtgtccaga cgataatccc
     4561 atagttcatt gacaagccat ttttttcccg tttcaagatc atggaacaaa gaaggatcaa
     4621 agccgttact atttaaataa attggttcgg accaaggacc tgtgatctca gatgcagtga
     4681 tcaaataatt gtggacatct ttaaacggac ggcctgcact tttgacatct gtgtaaacaa
     4741 gataaaacaa tccatcagca taactgattt gtggcgccca tatacttcca tttgtaggat
     4801 ttccttgcaa agatacttga gtggtcaaaa tatccgttgt atgtgaccag ttgactaaat
     4861 ttttcgactc atatactcgg attcctggaa gccattcaaa agaggagaca ataatgtaat
     4921 accgctcttt cactcttaat atattaggat ctggattgaa tcctcttaaa ataggatttt
     4981 tcactttgat agtctgcatg attcaggctc cttttctcat tcttactcga tataaactga
     5041 atgccccagc tgcgaaataa aaaaatgcaa aaggaaacgc aataaactga gtgccaatca
     5101 acaatatgaa tcctgttata aaatacaaac cagtggcagt tgttaagtat tttcctttag
     5161 cagtcaaaaa caatgctact gctaaaaaag caagtgaaat aaacaacaca acggcaaaca
     5221 gaccagtcat gtcctgtaat aatccaaatg tattttctaa agacaaagtt gaatgatcta
     5281 cagcaagcga ctgataactt tttttaaact ctgacgcaga catattactt aaagtaactg
     5341 ctaacccgcc aaagaaaatc aaagatagac tgccaccgac cattcctagc aatagttccc
     5401 attttctttt catttctgaa ccccctgctt ttctaaatgt atccattcag gtcttttgat
     5461 cgatgtttca taattgttat tacgttcaga gaatttgaca gtctgttcat ttttcttgtc
     5521 atcccaatta tcccaaccag ttgggtgaac atgcccacct atcttacacg cttcaaataa
     5581 gacatttgca tacggacgcc acggtcttcc taaatagacg tttctagtat caggttctgc
     5641 agtcaaggta cagctttcaa aacgataccc tgttttttga tttttcggcg tagatgctgc
     5701 tgtgatgtat ccaggatttt tactggctaa gctatggata tgacactgat gaaaaacggc
     5761 atctgcccca ccaaatatga aatccaccgt tccttcaatc cagcaatatt cataggtctg
     5821 acgacaatac tcaggattgg cagaagccgg tgtacaaaaa ggagtaccat ctttttgcaa
     5881 atcaggcaac ggacccgtgc ataaggtatc ctgataacca gatagtcgac agttttttaa
     5941 agatacgcga tctcctgaat tgaataaagc aacagcctgt cctacctttt ctcctggacc
     6001 tgctgtattt tcgatgtgaa gattttctaa tacgacattc gatccttcta agaaaaaagt
     6061 agcacttcgg aaagtcccta actggctacc gtcaagatac tcctgttttg caaaacgatt
     6121 accggagata actactgttc ctgctcccac aagtttaaaa ttggataatc tgctttctat
     6181 atattcatca tatcttcctt cttttactat caagaccttt ggatggctat ccggcaggcc
     6241 tgccaaataa tcgattcctt cttggatagt ttcaaaatcc gtcggggtat ctatagcatt
     6301 ctttccaatt atcagtttgt ctttcatcct cataaatgct cccttatgaa ttgtttccaa
     6361 atatttctca tttcttgtgt ttccatatga ccgcctgtta aagaaaaaga agaaaagttt
     6421 tctggactac ccattgattg atactttttg tccagccctt ttctcagctt cagtacgcct
     6481 tcgtccaagc acatcgtatc gttttttcca actaagctaa gacgagggcg cggagcgatt
     6541 ttttcttgga ttgctaacgt tgtataagct gtcaatagat ttggcacata gtaataaaac
     6601 ccatgatgat ctaggcggcg atgtagcaaa agtatttcga tgtccacctg tgccgctaga
     6661 tcaatacaaa ctttgacacg agaatccaat gctgtcaccc accagcttaa taagcctccc
     6721 atagaaagac caatcgttgc gagccgttga gtatctgtgt cttcccttgt ctccaaataa
     6781 tcgatcaagc tgatcacatc ataaatacgc attccccata acgtttttcc tgttaataaa
     6841 aattgtttga acaactcgct ttcagaaata cctccgcgtt cttcaaatcc ccaagcatca
     6901 atcgaccaaa cagcatatcc cattcctgtc agtacttctg caaaagatgg agaagctaag
     6961 taaggagcac catggatcaa ttcacttttc ccgactgaaa aatctccgcc gtgagaatgc
     7021 aggtaaagga ccggcggaaa cggtccttct ttttctggat aagcatagag ggctggtact
     7081 gtttccaatt catttaagta caattgatag tattcaagca taaaaccgtt ttgtttttct
     7141 cggtataatc gttttccact aggggtatgt ctgctagatg gagcacctaa aaaatcattc
     7201 aactgcataa gcaaagtttt tacgaacaac cagttcatcc atattttctg attgatttga
     7261 ttggaatttc tcaatactga tttctttagt attttctaat agaaatgctg gtccctcgtg
     7321 attttcaatc gacatctggt taaaggaaac cttacccgca aagccaatat aaaatccttg
     7381 tctgctcatt tcctctattc ctgtcatcat agcaggaaca ccgggaactg catcttgggc
     7441 catcgagaca tcgatattgt caaatgtgat ttcttgtatg aattgttccg ctaatccata
     7501 aataaaacct gcagaagcat ggacattcct tgccgtgata ttcgaaaaat ggatccttct
     7561 gaatgctggt gtccgttcat ctatcggata agcctttttt tcccatacat acggttcttt
     7621 ccctcgcgga ccacagaaat aataaagatt cagtataaat ggacacatca cattatccat
     7681 gactatattg gatactcgaa tatcttcaac gatcccgcct cgacctcgtc tagatttcaa
     7741 tcgtattcct cgatcagttt cttggaagat acaatttgaa atggtaatat tacgaatact
     7801 accactcatt tcacttccta atacgacacc gccatgtcca tggaccatcg tgcaatttgt
     7861 gatcgtgata ttttcgcaag cgatcctttc gtacgtatct tcagtccctg ccttgattgc
     7921 aatacagtca tctcccacgt caatatggca attactaata cgcacatttt tgcatgattc
     7981 tggatcaatt ccgtctgtat ttggtgaatc cgctgggttc aagatcgtca agttatcaaa
     8041 cgttgcatta ctgcaaagaa tcgggttgat cgtccaactt ggtgactgga tcaatttaat
     8101 atctttcaca gtaattcgat gacagttatg gaaactcatc aatttaggac gaggataagc
     8161 gagattatct ggttcatttc taaaagtatg ccaccatttt tttccatttc catctaatgt
     8221 accgaaacca gtgacagaga tgttctctac attttgagca tagatacagg aagcataaac
     8281 ttttcgatgg actccttccc aacgtgaatg aacaacagga taatcttttg gatcgtcaga
     8341 gaatttcaga accgctcctg cgcttaaatg aagttcgaca ttgcttttta aaaataaagc
     8401 tcctgttaga aattcacctg ctggaacaac tacggtcccg cctccgtcac ttgctgcagc
     8461 atcaatggct tgttgtattg cttcagtatt caattcatca attgatgcgc caaatgtcaa
     8521 aatatcatac atatttataa tgcctccact tcaatcaatg cttgcaagaa tgcaccaacg
     8581 cctttttgat cattacaaat aattggttca ctgatgtagt aagcatatga accatctcgc
     8641 tgatctgctc cgcctaaccc tgctacttga cagtttttat tcaagttcag ccagccttct
     8701 tttgtttcca gaacaaattc atcaagtaat ccttgatgtg atttcttcac ttgtggaagc
     8761 cattcttctt tgttcagcag tcccaaacgt attcctttag ccattgcgta aacaaacata
     8821 ctactgccgg aagcttccag ataatttcct ttccgttttg tttctgttgt tacttgatac
     8881 catgtcccgc tgttttcttc ttgatatgga agtaatgcag ccagtgtctt ttctagaatt
     8941 tctttcagca aagaacaatc tgtttcttca tgaagtaatt cataggtatc tgctgcagcc
     9001 atcaaatacc agccaatcga tcggctccaa aaatgatggg atagacctgt ttttggatca
     9061 gcccatggtt ggaccttctt ttcatcccat gcatgaatca gcaaatttgt ttttggatcg
     9121 aatagatgtt tataactgat ttcaaactgt ctcaaaacat cttggtaatc tttttcttca
     9181 ctaaaattct ggataaattc agcataaaaa ggagaaccca tatataagcc atccaaccaa
     9241 atttgataag gataaatttc tttatgccaa aaagctcctt cggatgtgcg tggatggttt
     9301 gccaactgct gggaaaggag ttctgctgct tttttatatt tttcttcgcc tgtttctttg
     9361 tacaataaaa agaaaagctt tcctgtattt acatggtcga tattgtattc ttcaacgctg
     9421 tagccacgga tcgttccatc ttcttgcacg aaatagtcga tattgtcttt tatgaaatca
     9481 aaataaattt tttcttgggt tcgttcccaa agtaattgga accctttaag tacgacgcca
     9541 tagtcataag accattttcc tttataccac ttttcttcat ataagcgagg tgttctttcc
     9601 atgatacttt ttgctaattt ctttgaccag ttttccatta tttgctctcc tttaaaaatt
     9661 aaaataggat ttgggacaaa taccaagaag tatttgtccc aatcgtctat attactgtgc
     9721 cgctgctttg tatgcttcct cgtactcttg tgtgattcga tcgcctcctt gtgctttcca
     9781 gtcttctaca gcttttttga atccatcttc gtcaagctgt cccatgatgt attgcaccgt
     9841 agcatcaatg acgatttttt caatttctga tcctacttca ttgttcgtcg gtgaatccaa
     9901 tggcacagaa ggatccatta cagcaaattc ttcattttct ttgatcaatt gattagagaa
     9961 ttctttttca gggtctgtat ctttgaaaga gaacgtcact tcactaggac gagagcttga
    10021 taacggttgc acctcttgtt gccaaagatc catatcgata aattcgatag aaccatcatc
    10081 attcaattca taatgcgttc cttcgatacc gccagtcatc aatttataca catcttcttc
    10141 taaaagatca tcaacaaatt gaagtaattt cttcaattgt gcttcgtctt ttacttgaga
    10201 tttgggaaat gctagcaagc cgccaatacc atttccttct gaccaaacat gataaccgcc
    10261 gccttcacca tctgagatct tgtttacagg cactaattcc atatcatctt gaataccttg
    10321 acccatcgtc ttcagattct tgatatccac cattccagtg tagattccag ttcttccttg
    10381 tgcaaattgt tcttgctgat cagtcttttg ggtaactgca aagtcttgtg ccaaatagcc
    10441 attctcaaat agatctcttg aaaaattcaa agctttcata tactcttctg tatcaaattc
    10501 tggagtgaat ttgccattat cgtctacagc ccagccattt ggtgctccaa aataagaagt
    10561 gaaaagttta aagctggtat aacgaatatc actaggcgca cgatcgccaa aaccaactgt
    10621 gtcgtccaca ccatttccat caggatcgtt ttctgtaaat tgtttagcta cttcataaag
    10681 ctcatccatg gtagttggaa catctagtcc tagattatcc aaccagtctt ttcgaatgac
    10741 taagccagca cgagcgtagt ctttttgtat cggtacgccg tacaaggcac cgtcgatact
    10801 cgcagcttcg attctatctt cagaaatttg acttaaattt ttatagtctt ttaaatattc
    10861 tgatacatcc cagaatacgc ctgattttaa cgcattgcgg acagaagagt ttttcaacat
    10921 cgcaatttga agtgtaacga tatctcctag ttcatcagaa gccaatgcag ttgttaatct
    10981 ttcttctttt gaagcatcag gaatccagtt gaatgtcagt tccgtatcgg ttttttcttc
    11041 gatcaagttc acaatcgtgt ctgtaggcgg tgaagcatga tgcaaaatat ttaaccaagt
    11101 gattttagct tttccatctt ctgtctctga agaactgtta cttgaactgc tgccgcatgc
    11161 ggcaagtgct agaattcctg caaaactaag acctaatttt acgagcgttg cttttttcat
    11221 aaattttctc cttcactgtt ttaataatat ttttgttttc ttctgttttt tctgtatatg
    11281 agttcttcca ttccaaatgg caaaatatag aatttgctgt ccacgtgact gcggaaaaga
    11341 agagactgcc accgataaag gttaaaacac ctggcattgt ttggatgatc atcagataaa
    11401 tccctaccat acttaatatc aacactaatg agtaatgaag atgtgagaat ccgaataaaa
    11461 atgccatttt cattttgaaa aaatatcctt tccaatcata atgagccatg attgggaaaa
    11521 tatagagtgc tgagagcaca tatatgaacg cagcaatata caaagcgatc ctaagatacc
    11581 aattgtgtat gaaagaaaga tccacaagta aaacaatccc gatggcgcca tatatccagc
    11641 tcatcagcaa ggtttcacga tagttttctt taaaatatgt gaagtacgtt ttcgtcaaag
    11701 gaaacgtttc ttttgagcgc agccattttc taatcactgc aaccatcgca tacgatgcag
    11761 gaccgaaagt aaaaactccc aaacctgcga tgactaaacc gccccacaga aaattcaaat
    11821 aaaccaactg taaaatacga tttagccttc cgtttatttt atctaatgac tgcagcatat
    11881 ctttccctct ctttctatct tagtaaacgc cgtcttctcc tagctttttg gcaatcttat
    11941 tagctaaaat taccataaac aatcctacga cccctttaaa caatcccatt gctgtactga
    12001 aacttaactg tccattcttc aatccagctg tataaatata ggtgtcgaaa atttctgcaa
    12061 cgcttcgatt caatgaattc aataacaagt acatatgctc gaaccctaag tctaatgtct
    12121 gaccgatttt tagaatcagc aaggtaatga ttactggacg aattgccggc aatgtaacat
    12181 gccatgtttt gcgtaagcgt cctgctccat ccatttctgc agcttcatac aactgtgtat
    12241 cgactgcagt tatcgctgaa aggtagatga tcgtagacca gcccaactct ttccagatca
    12301 cttgtccgat atatactgtg cgtgtccatt caggggatgt tagaaaactg attttttcaa
    12361 atcccattgt tgcaaggaat tcattcaata cccctccgtc aacattcaaa aatacataag
    12421 taatcgaaac aatgattacc caagacatga agtgagggat gtaaatgatc gtttgaatcc
    12481 cgtttttcaa tcgtttgttc gttacttcat ttaatagtaa agacaaaatg attggcatcg
    12541 gaaaaaacac gaagatattt aatccgaaca agatcaacgt atttcttaat aatgtaaaga
    12601 atgtcggttc tgtaaacaaa cgaatgaaat gtttgaaacc gacccaagga cttcccatta
    12661 ttcctaaaaa tggttgataa tcttgaaaag caataacgag tccccccata ggaagatacc
    12721 taaaaatcaa gaaataaagg actcccggca gaatcatcac atataaaaat ttattcgttt
    12781 tgattcctgc aattattttt tttcgtcttc tgagcttttc ttcttttttc gatagcgtca
    12841 gttgaaatgg ttcttgtttc tttacacttt ccataagccc ctccttagtt ttgtgaatgt
    12901 ttgctgctta tgacttcatg atagataact atctgaatta cgtatataat catttttacc
    12961 gtaagtaaaa acgcttacat agcaatgatt tttgtgctat acaaaacgat aaagtgtatt
    13021 ttttcacaaa taaactacgc atagcaaacc ttctattttt ttctatctga cacttagcat
    13081 aggaaatgat tatatacgta atctttcacc gatgataaat tgaacatata gaaacagaaa
    13141 catttaattt attttgagga ggagcctatc tatatgaaaa agaaagtctc tataggagaa
    13201 agaagtttta cacttttcaa caatacgttt ctaattttgc tagctttgat ctgtatcgtt
    13261 ccttttttaa atatcatcgc tacatctttt gcttctacac aagaagtcgt cgcgaaaaag
    13321 tttatccttt ttcctactac cttttcttta gacgcgtatc gctacattct ttctacgccg
    13381 accattttta gagcacttgc tgtttcgatt ggtgttacag gtgtcggaac gatcgtcagt
    13441 atgtgtgcaa cttcactgat ggcctacggt ctttccagaa agtatttgtt tggtcgaggt
    13501 ttcgtcaact ttcttgttgt attttctatg ttgttcagcg gggggatgat tccaacgttc
    13561 ttagttgttc gttctctagg gctggtcaat tcttactggg ccatgatcct gcctgtggct
    13621 gttaatgcaa tgaatatgat cattatgaga aactttttcc aagccttgcc ggatagtttg
    13681 gaagaatcag caaaaatgga tggttgcaca gattttggtg tatttttcaa aattatgctg
    13741 ccattagcgt taccgtctat tgctactatc tcgctttttt atgctgttac ttactggaac
    13801 acttatatga ctgctatttt gtatatcaac gattcatcta aatggccgat acagattctt
    13861 ttacgccaaa tcgtcattgt atcaagtggg atgcaagcag aaagtagtgc cgttgatgtg
    13921 attccaccag cacaaacagt taaaatggct gttatcgtta ttgcaacagt gcctatgctg
    13981 attgtttatc cttttgttca gaaatatttt gtcaaaggag cactcgtagg ttctgtcaaa
    14041 gggtgattat gtactgaacg caaaatggta gttgtgtcag aagtggtcag cttcaagaaa
    14101 taagaaggca tttacgaaaa ttgcttctta aatttttgtg aaatttcggc ttatttttcg
    14161 aagaatctac tcctggaaca ccgtgtatca gaggttgtga aagagacgtt cagccttgag
    14221 cgatgataaa aactctcaca aacattgcga cgagtaaccc acaggagcaa taagaagcga
    14281 ttttgaaaaa tagcttccca tatttcacaa aattatgcct tattgtcgat agcctgtctc
    14341 ttgaacgcca tttattcgta aaaaagaact gtgacaagac ttttgtcaca gttctttttg
    14401 cgtgcttagc cttgaaattt aactatccat aaatacaaat actagggtta ttctaacttc
    14461 ttttattgct tgaatcagtc cacaagaaaa acagcctctt gattcacaaa tatttttttc
    14521 gatattctcc cggcgtaatc gattccttct ttttaaagaa acgaataaaa ttttgcggat
    14581 ttcgatattg caatctttct gcaatctctt ttacggagag gttagtctct ttcaaccatt
    14641 tttttgctac ctctaaacga tgattttgaa caaaatcacc aaatttttct cctgtttcct
    14701 ttttaaatac attacttaaa tagttagggt tataatgcaa cctatcagcg atcacatcta
    14761 aagacagatc acgatcatat tctgtgtaga cgatatgcat aatattctcc gacaaatttt
    14821 taaattcatg atcagtgatt gcttgagagc attctgtgat tggcagaact aattgttcta
    14881 aaacaagttt ttctagttct ttgggatgat aattgttcag tgcttttaca taaatttgtt
    14941 tcatgttatc aaagtttttt gaatctactc ccaataactg tcctaattga acgagttcat
    15001 tgatcaagcg gaccgaaact acttcccgac tcaaaggatt tttattttgt gcaaacaatg
    15061 catcaatcaa ttcatgtact aaattcttca cttcctgatt tccagaacga atggcttcaa
    15121 acaatcgatt ttgttcttct atcggatatc taataagtgt tttttcatga gcagcaggaa
    15181 cgatttcctg ataaaaaata attgaacttg gaccagtatt tacacgataa tacagggctt
    15241 cttttgcccg atcaaccgat tgcttgcttt cattcagcgt ttcgaaccgg ttactgatgc
    15301 ctatactgat agttaaattc aagtattctt ttacacgttt ttgaatgagt cggcaatact
    15361 ccatgacttt tttgcttgct tctgcatcat ctttatccat tcgataaata gtggcttgca
    15421 tttcttcatt caaaacgatc ggcagcattc gattttcctt tggcacaatt tccgtgatca
    15481 tgttgttgat cgctaaaagt agcaaatcac gctccccacc gtgactatct tctaacagat
    15541 cgatttgaac caaagctgta taatagcagt cattttgaga actataacca aattgctgca
    15601 accgctgatc tagttctcgc ctttctactc gatttctaaa taaactaagt acaaatagcg
    15661 tttccagctg tggcttttgg gtaactaagt gtgcacttaa cgcttctttt tctcctatga
    15721 tccgactgac tgattgagcg accaaatcta gttctttccc actgaatcct tttgatttaa
    15781 gattcagacg ttcctgtatt tgagaaatcg gacgggcaaa tctgtccgaa aataagtagg
    15841 aaagaagacc aatgagtcct accagtgtta aagacactgc aactagcccg attctcagat
    15901 tgcggatcat tgcgccaatt gcactagagt caacttctaa tctgtaaatc caattattat
    15961 aatctgattt cagtactata tacgttttat ctttttctct tatcactttc agctgattgt
    16021 aatctagatc cacgtccgtt aatacagttg gttgctcttt attttttact gtctgagtag
    16081 taaaaaggtt gccaacttcg ttttcaatag aaagtatgtc ttctccactt tcaccaacaa
    16141 cttgttctat tgtatgtttc tctatcgtag caattcccaa tgcatatttt tctttttcaa
    16201 acattggcaa agaaatcacc atttcgattc ctttgttttt cttttgccaa aataaattat
    16261 ttttgttatt tatgtacttc tgttgatact tttcaacttc ctcttcggtc agttgactca
    16321 acgatccatt gattactccc catttaccat ccaaactgac taaatcataa ttattatcat
    16381 ccataacaat cgtttctata aaatttagtt ctttcctgat ttcagaataa gtggagtaat
    16441 ctgtatatgt cagcggatgc ttgaatatgt ccgagaaatt tttggtcgaa ccatacgtag
    16501 aaaacgaata ttcaatcgtt ctaattttcc attcaacgtt agttttaact tgcctgagca
    16561 aattcttttt gtctgttaaa taactcgatt cgatcgattc ataggtattc tggtaaatga
    16621 ataaactaaa tcctatgaca agtacggctc ctaataaaaa catcggtaaa aatattttat
    16681 aaaatactgt acttttcttc attttcttcc tctcctcctt ttaaaataaa aggctttcat
    16741 ttttctgtaa aattgatact catctaatta aatgagcatt ccccgctttc aagaatagca
    16801 taattaaaaa taaaaatcca agtaattttt aacgtgtgca atcttttcat atcaaagatc
    16861 tattgactta tcgtagttat cgtaatatga tgaatgcgtt aacaaaaagt gaaaaagtaa
    16921 ggaaaatgat ggaatggtaa cgatcaaaga tatcgctaaa gcagctggcg tttctcatac
    16981 gacagtttct cgtgctttga ataacagcag tttaataaaa aatgaaacaa aacaaaaaat
    17041 acgacaacta gctaaggaaa tgaattattc gccaaactat agtgcaaaag gtttagtgaa
    17101 tcaaaaaaaa tatctaatcg gactattttt ctcaagtttg cataaaggaa cttcatcaaa
    17161 tttcctagca gattccattg caggcatcca ttcagtatta gacacaaatt acagtttatc
    17221 tgttgaaagt atcgatgttg ttgatttaac agaaatcaac ctgcaacgct acgatggact
    17281 gatcgttatg agtcaaagtg atgatgatca gcctttcatc gactatctca aagaaaaaga
    17341 atttcctttc gttgttgtca atcgtcacat caatgatcca gcggttatca acgtcactgc
    17401 cgatgatgcg gccggtgtta tgcaggcagt agattacggt attggatgcg gacatacgaa
    17461 gatcgcttat attggcggaa agaaaaattt tcgttcgaca aaagaacggg aaaaaggggt
    17521 attgaaaagt ctaaaaaaag cgagcatccc tgtcaatcca gcctattttt taacaggaga
    17581 ttacagctta gaaagcggcc tccaaaacat ggaataccta ttatcacttt ctgacctgcc
    17641 tactctggtt ttttgcggca acgacgacat agcgattggt gcattgagag ctgtacattt
    17701 agctggcctc cgtgttcccc agaacatttc tctgatcggg ttcgatgatt ctccagtcgt
    17761 ctcctatctc aatccgccgc ttaccaccgt acgtaagcct ttgaaagaaa tgtgtcaaga
    17821 aggaacaaag cttttactag atttgatcga aggcaggacg atcgaacaat ctaaaattga
    17881 gctctccacc ttgttgatcc ttcgtgagtc gatcaattac ttgtaaacta caagtaattt
    17941 tatataaaaa tgttaacgtg tgcataacac agaaaggaag tttatatgaa aaaactgaca
    18001 aaagaattag tgaaaaaaaa cgaagcacct gtaaaagttc ttcagtttgg tgaaggcaat
    18061 tttatgcgtg gatttattga ttggcagatt cagcagctga ataaccaaca attgtttaaa
    18121 ggtaatgttg caatcattca acctttagaa caaggtcttg gaaatatgat gaaccagcaa
    18181 gataatttat atacggtcat tttacaagga ctcagcaatg gcgaaatcgt tgatacttcc
    18241 gagattatca ccgtagtaga acaaatgatc aatccttatg atgaatggga tgcttatcta
    18301 tctctagcag aaaatgacga cttggcctat atcgtctcca atacaacaga ggcaggaatc
    18361 caattcgtgg agactgataa tttaacagat actcccccac agagcttccc gggcaaactg
    18421 acagcctttt tataccgacg tttcaaatta aacaaagctg gctttaccat cattccttgc
    18481 gaactgattg acagaaacgg cgaacgtcta aaagaaatca ttttacgcta cgcagaaaaa
    18541 tgggatttag aacctgcttt tgttgagtgg ttagaaaaag aaaatgtttt ctgttgtagt
    18601 ttagttgatc gcatcgtccc aggttatcct cgcgaagatg caggtgtttt caatcaacgg
    18661 cataactatg aagatcaatt gatggtcaaa gcagaaccat tcatgctttg ggtgatcgaa
    18721 gggcctaaag aattggagaa tcaactacca ttcaaacagg ctggcttgaa tgtcatcatc
    18781 acagatgata tgactcctta tcgtgaacgt aaggtgcatt tgcttaatgg accgcataca
    18841 gcgatggtcc ctcttgcttt gttggcggaa ttggaaactg tagaagaagt aatgaaagat
    18901 cctttattct ccgcatatgt tgatcagtta ttcaatctag aattgattcc tatgctttct
    18961 ttacctaaag atgaattagc catttatgct gaccaaatca aagaacgttt cttgaatcct
    19021 tttgcccatc acaaattaga agcgatttca ttaaatagtg tttcaaagtt cagcacccgt
    19081 ctgcttccag tgttcaagaa gtatatcgaa gaacaaaatc aggtaccacc gttaatcact
    19141 gtttcactag ctgcgctact tcttatgtat cgaggcgatc aagtaaagcc acatgatgat
    19201 gaaaagacga taagcgaatt tactgatgct tggtctgata atggaacagc tattcctcga
    19261 ttattgcaaa acgctgcgct ttggggagaa gatttgtctc aaataccgaa tgtgacagat
    19321 acagttcaag aaatagctgc aaagatcgat caaaaaggtg tccggtcagt attacaagaa
    19381 atgaaaggaa cgatggtcca tgcttgaaac cctgcaacca acaatgaaat taaatcgacg
    19441 agacagtgtg gtcgtcgcat taacccctat tccaaaacaa acacaactga cgattgatca
    19501 gcaaacgatc accactcttg aagatatccc gcaaggtcat aagattgcat tgggtgattt
    19561 gaaagctgga gacaacgtga tcaaatatgg ctatccaatc ggtcatgtga cgacagacgt
    19621 aactgccggt caatggctgc acactcataa tgtaaaaacc aatctttctg gtgaattgga
    19681 ttatcgatat gaaaaagatg tccatccaag tcattacctt tttgagaacc gaacatttca
    19741 aggttacttg cgaaaaaatg gaaaagtagg gattcgtaat gatttgtttt tagtacctac
    19801 cgttgggtgt gtgaatggca ttgctgaact gatcgtcaaa cagttcaagg aaaaacatcc
    19861 agatctggga cagtttgacc atattacgat tttaaagcat ccttatggct gttcgcagct
    19921 tggaaaagat catcaaaata ctcgagaaat tttagcggac gcagtaaatc atcccaatgc
    19981 cggaggagtt ttagtatttg gattaggttg tgagaacaat acagttcctg aattcaaaaa
    20041 aattttaggt gaatatgatg aagaacgagt gaaatttcta gtggctcaag atgtttacga
    20101 tgagatcgaa caaggtgtgg ctctattaga agagctttta acagcggcgg aaaatgacca
    20161 gcgcatatca gtcccgctct ctaagttgaa tgtcggtttg aaatgcggcg gttctgatgg
    20221 tctatcggga ataactgcta atcctttact tggtgcattt tctgactact tgattgctca
    20281 aggaggcagc acgatcttaa cagaagtgcc agaaatgttt ggcgcagaac aagtattgat
    20341 ggcacgagcg gaaaatgaag aagtttttga ctcaatcgtt gacttgatca atgacttcaa
    20401 acagtatttc ttgtcttacg gggaaccagt ttacgaaaac ccatctcctg gtaataaagc
    20461 aggtgggatc actacattag aagataagtc tttaggctgc acgcaaaaat caggaagctc
    20521 tcctgtcgtt gatgtgctac aatatggcga aaaaatcaga aaaccagggc ttagtttatt
    20581 gcaagctccc gggaatgatc ttgtagctgc ctctgctctt gcttcatccg attgccagtt
    20641 ggtcttgttt accacaggaa gagggactcc gtttggctca tatgtcccaa cggtcaaggt
    20701 atctacgaat acaactcttt ttgaacgcaa aggtcattgg atggatttta atgcaggcgt
    20761 cttattagaa caaccaatgg aagtaatctt agaatcgttt gttcaaaaaa tcatcgctgt
    20821 agctagtgga gaagaaacga aaaatgaaca aaatgacgtt cgagaaattg ccatttttaa
    20881 aaacggagta acactttgat tttcataaaa cagtataaaa agaaagaagg aagatttatg
    20941 tttttatctg atgatttttt attaaaagac gattgggcga aaaagcttta ccattcctac
    21001 gcaaaaaaca tgcccattat tgattatcac tgtcacttag atccaaaaga aatttacgaa
    21061 aacaacaatt tcagcaatct gacagaagct tggttaggag gcgatcatta caaatggcgc
    21121 ttgatgcgag cttgcggcgt gcctgaagaa aaaatcacag gaaatgcttc tgattttgaa
    21181 aaatttttag cttggtgtca aaccgtacca aaaattatcg gaaatccgct ttacagttgg
    21241 tcacatcttg aattgaagcg tttcttcggt attgacttgt tgataaatga agaaaatgca
    21301 gagaaaattt ggacacaagc aaatgaaatt ttggcagctc ctgattttcg ccgtcgggaa
    21361 atcgcaaaaa aatcgaatgt agaagtgatt tgtacaacag atgatcccgc agacgacttg
    21421 cactatcatc agttgcttgc tcatgaagaa ccagatttga aggttctacc ttcattccgt
    21481 ccagataaag cactcaatat tgaaaaagaa ggatttaatg catgggtcac actactggaa
    21541 gaagcagctg accaaacgat caccacctat caagaactga tagaagtctt agggcagcgg
    21601 atagaatact tccatcaaca tggatgtcgt gtttccgacc acgctttaga catcttacgc
    21661 tataaagaag cggatgaaac agtattagaa gagatttttc aaaaagcacg agctaacaaa
    21721 ctattatctt cagatgaaat cgatgcttat cgtacagaaa cactgataca tttgacccac
    21781 ttctatcatt ctcataattg gacgatgcag ctgcacatcc atgcttatcg taactgtaat
    21841 acacaaatgt tggaaaaatt agggcccgat accggctatg atggaatgaa tgatctttct
    21901 ttgactattc ctctgcaaaa attattgaac cgtgcagaag aaacggatca gttgccaaag
    21961 acgatccttt attcattgaa tccgaatgac tatcctgcga ttttagcttt gatgggctgt
    22021 ttccaaaaag aacagaatgg aaaactgcag ttaggttctg gatggtggta caacgatact
    22081 cgagctggta tgcgcgatca attgacacaa tttgctgatg gtagtgcttt ggggaatttt
    22141 gtcggcatgc tgacagattc aagaagtttc ctgtcctaca ctagacatga atatttccgt
    22201 cgtgttcttt gtgaattttt aggcgaaatg gtcatgcgag gagaagcacc tgaagatgaa
    22261 caacttttag gaagtctagt tcaagcgatt agttatacaa atgctaaaaa ttactttggc
    22321 ttttttgcct aattgattaa tagtaacagt aacgaatcaa aaacaggata gtgaaataac
    22381 ggaatccgtt tatccacgtt ttagagaaga agacggacca aatttgctcc gtcttcttct
    22441 cttgctgttc tgcttcattg cctataaacc tttatgaaag aagagataac atgcctacta
    22501 tccatattgc cggtgattct actgcggcag aaaaagatga aaacaagcgt cccgagacag
    22561 gttggggaga aaaaatctct gcttattttt cacccgagat ccagatcaat aaccaagcaa
    22621 agaatggacg cagcaccaaa tcatttatcc aggaaggaag gttagcccgt ctagcttcac
    22681 agtttcagcc gaatgatttc ttatttgtac aatttggaca taacgaccag aaaatccaag
    22741 aagaaagagg tacgcttccc ttcggtagct atttaaaaaa tctgcagata ttttttgaat
    22801 gcgcaaaaaa agcgaacgtc caaatggtct tactgacatc tgtgacgcga cgagattact
    22861 tagaaaacgg aacattgaat ccagatatac ttggagacta tccaaaagcg atgcgtgcat
    22921 ttgctgagaa acaccatatt cctcttttag atgtgttctc aagatcacaa gaattgttcc
    22981 agaccttctc aaaagaagag acaaaaaaat tctacctgca tcttatacct gatacttgta
    23041 aaaattaccc agaaggacta aaagacaata cccactttag tccagaaggc gctgataaag
    23101 ttgcccgaat aattgttgaa ttgataaaag aatcccgtct gcctcttgct aattatttac
    23161 aaaaaggagt ttgagatgtt tccattaaat ttaggcatcc gtgcccacga tttagatgtt
    23221 cgaaatcgtg aagaaatcgt tcaaaaagta tcacagcttc acttgtccca tatccaattt
    23281 gcaccacaaa aagcatttcc tgaacaactt aaattaactg acatgacact tgggagtgct
    23341 gcctattttg gtgaatactt ccaaaaaaac aatatcgaac tttccatttt aggatgctat
    23401 atcaacctat ccagcaaaaa tcaagaagtt cgtgcacaag cattggcaac tttcaaacag
    23461 caaattgctc tgtgctctgc ctatcaagcc aagatgattg ctacggaaac cggtagtgtc
    23521 tctgtcggtt acacaaaaga aaattttact gaagaagctt atcagatcgc cagaaattct
    23581 atcattgaat tagtcgctca tgcagaaaat tttggcgtaa ctgttgctgt tgaagcaggg
    23641 atcaatcatc caatctataa ctatcagtta gctaaacgtt taatcgatga agtagcttca
    23701 ccaaatttaa aaatcatttt agattgtgcg aatttgatgc ataaagaaaa tcatgctgat
    23761 caggaaaaag tgatccgagg tgccttggac aatttacatg gttatattac agcgcttcat
    23821 ctcaaagact atatcatgga aaatggaaag atccgcatgg tacctgttgg caagggctgt
    23881 ttagatttcc gcccggtact gcattatatc aaatatgagc gtcctctaat gtacgccact
    23941 cttgaagcta ctcctgagat ttatgttcct gaagcaatag aacacttgca gtttatttac
    24001 caagattgtt aaggagaaga ttatggagga acgaatacag aaaagttatc aaaaatatca
    24061 tgcaaatgct tttcagacat tgctgcatct ttatcaggga aattattggc gttttgccat
    24121 gtcaggactc ttttttatta tcaaacatct tccatcttgg ttaatgccga tcgctattgc
    24181 caatgtaatc aatgcagctt catcgaaaga ttcttctcag ttgcaggcca tttatttcaa
    24241 cgcttttttg atggcttgtc tgattggtca aaatatattg acgaattatt ttcatgtaaa
    24301 ataccatagc acttcgatcc gtcaagtaga agctggacta agagcgaccc ttatcaagaa
    24361 aatccaagaa ctatctattc cttatcaaaa agaattgcaa tctggacgaa tccagtcaaa
    24421 gatcatccgt gatgtagaag ctatccaaac gttgtcctct caagtatttg tcagcggatt
    24481 aaatatcgct gtcaatttat tcgtagcttt aggtatcacg ctttataaaa gtcctgttgt
    24541 tttcatgttt ttcttattga ctgttcctct cgccgcattc gttactctct ttttccgtaa
    24601 aaggatcaga cagtccaact cagacttcag gcaagaaatg gaagagactt ctgcaaaagt
    24661 gatcgaagtg atcgaattag caccgattgc tcgagctcat gggttagaaa aacacgaaac
    24721 aactcgctta aataagcatt ttactcaaat ctatgaaaaa ggattccact tagatatcct
    24781 gcaatctgtt ttcggatcag tcagctgggc tagttttcag atatttcagc tgatttgttt
    24841 gattttcact gggatattag ctttacaagg gcgcatccaa cccggcgatg tcgtgatgta
    24901 tcagacgtat ttcacgacga tcgtcaattc cgtttctgga atgatcacgc tgattcctac
    24961 gatttcaaaa ggcatggaat ctatcacttc tattggcgaa ctgttgattg ctggcgatgt
    25021 agaaacttat cacggtaaga aaaaaatcca acatttggat ggaaattttc gttttgagga
    25081 tgtttctttt ctttatccgg actcactcaa accgattatc gatcattttt ctctagaggt
    25141 gaaagctgga gaaacaattg cttttgttgg gccatctggc tctggaaaat ctacactcct
    25201 taacttattg attggattta tccagccgac ttcaggaaaa atttttctag atgatcagcc
    25261 tttggatgaa ctggatatgc gaagtgtgcg aaattattta gccgttgttc ctcaaaccac
    25321 tttgttgttc tccgcttcga tcaaagagaa catcacttat ggcttgaaaa acgtatcaaa
    25381 agaacgttta gatgaagtca tcgaagctgc gcaactttct tcactgattg accagcttcc
    25441 tgatggtctg gataccttag taggcgaaca tggcaacaag ctgtctggtg gccaaaagca
    25501 acgtatctcc attgcacgag cgttgatacg tcagccaaaa atcattttgc tagatgaagc
    25561 aacctcagct ttagataacc agtcagagaa aaaaatccag caagccctga attacctgac
    25621 agaaacaccc actactttta ttgtggctca tcggctttca acgatcaaag aggcagataa
    25681 aatcgttgtg atcgatgaag gaaaaatcgt tgaaataggt acttacgaaa aactgttagc
    25741 tcaaaaaggc tatttctacc gcttgaaaaa tgaatgacaa aaaataggag ctatgacaag
    25801 acttttgtcg tagctcctat ttctgaataa acggtgttct cctgccaact cctcggtcac
    25861 aagtcacaat agtcatcaaa catgagaagc tgttttttga aattgttcct tgtaactcag
    25921 agttaaacgg taggctcacg acctcttggt aaatggtgtt caagagacag cctatcggca
    25981 ataagaagca attttgtcat cgctcaaggc cgaacgtctc tttcacaccc tctgttgttt
    26041 cataaaatag ttttattcgc tgtaaaggtc gcgaactggt gtcatgatga tacggttcaa
    26101 gtcattgatg attgtactga agccttgctc tttttgcatc aagtcattga ttacttcttc
    26161 tgattggatt ttcacagcca tttcttgtgc tttcattgca tcttcgtcgc tgaactcttg
    26221 tccactcatt tgtttttctt gtaattcgat ttgcatcgct tggaagtctt tgaacagttt
    26281 gtgtgcttct tcgtttgctt gtactttctc gtacgcttct ttcaacgctt tgaattctgg
    26341 taattcacgg atctcacgtt cgatttgatt cgcgctatcg tagatgtttg acatgttatg
    26401 ccctcttttc ttttagtagt tactctctat tgtaacatgg ggttattcgt tttcaaaggg
    26461 gctactctcc ttgatatttc cgccagaggt ctttagccgc ttcaccaatt ccctgaacgc
    26521 cttctttcac catatcgccg aagtttttca gcccttcttt tgcttgttca ccatattgat
    26581 tcaagttatc ttgccaattt ccagactctc cattagaatt tcctgtgttt ccaacttgat
    26641 ctgcagctac cacttgtcct cctgtggcat aggcatctgc tacactaaat cctgtttttg
    26701 aagtatacgg aaggatgcct tctgccgctg atttgaagac tttcccgaca acatttccac
    26761 ttgtcccttc caaatagtgc agcttgctgg attcttcgta acccatccat gtcgaaatca
    26821 ctacgtctgg cgtgtaaccg atcatccatt ggtcatttgc ttttgtggca tcgaaattag
    26881 tttctgtggt tcctgttttc cctgctatcg tataacctgc aggattcgca gcagccgctg
    26941 ttccatttga aaatgtacca agaagcatgc tggtcatttc atcggctgtt tcctttgata
    27001 tgacctgttt tggttttttg tttgtgttat cgacgatcac cgctccagtc gaatcaacga
    27061 ttttcgtgat aagatgcggc gtatacatct gaccatcatt ggcaaatgca ctgtaagcac
    27121 ccgccatgat caatggagat actccttttt ccagtccacc aagggctaag ccataatact
    27181 tatcagattt tgctaaaggc aggccgaatt cttctgcttt atcatatcct ttttgtaaac
    27241 cgatctcatg caaaagccat acagtaggca aattcaaact ttgtgcaaca gcttgataca
    27301 tcggtacttc tccttggtat gtcccgtcaa aattatgcgc atcgtaataa ctttgcggtt
    27361 cgtctttcaa gatactggaa ggcttgtatc cagcttccag tgctggtgta tatacgctta
    27421 atggtttgat cgttgatcct ggtgaacgac gcatctgtgt agcaaagctg aatcctctaa
    27481 agacatgatc tcctcttcgt cctactagtg cttgtacacc acctgtattc ggatctaaag
    27541 ctactgaagc agattggacc atggcaccat ctgaagcatt tgctgggaat aatgcactgt
    27601 tttgataagt agcttctaat tgcttttgat aatcctgatc taaagctgta tagattttat
    27661 agcctttatt catgacatct tcttcatcaa gaccatactc gttaactgct tcatcgatca
    27721 ctgcatcaaa ataataagga taacgataac cagaatctga attatcgtat gtgtcattaa
    27781 gatacgcgct gatatctgtc tggctttctg cttgttcttg ttcttttgtg atttttccgt
    27841 tttcttccat tacacttagt actgtgtttt tccgatcatt cgcatttttt gggtgatcga
    27901 tcggattata aataccagga cctttcagca ttcctgccaa agtagcagcc tcagacagcg
    27961 taacattcgt tgcatctact ccaaaatact ttctggaagc gtcttggaca ccccataccc
    28021 cgttgccaaa ataggcattg ttaagataca tggtcaagat ttcttctttg ctgtacttct
    28081 tttcgatctc gattgccaaa aataattcct tcgcttttcg atcaaacgtt tggtctaatg
    28141 tcagatacgc atttttggca agctgctgag tgatcgtact tcctccgccc cctgatgttc
    28201 cgccagacaa gaccattcgg actgctgcac gggcaatccc tttgatatca aacccgtgat
    28261 gctcgtaaaa attcctatct tctgtcgaga ttactgcatc ttggatatag ggagaaatcg
    28321 cgtttaattc tacatatgtt cctttttggg cgtacagtgt gccagcttct tcgtttttct
    28381 tatcataaat gactgtcgat tggcttaatc ctgattttaa cgtttcgaca tttgcttgtt
    28441 ttgctaaaat aaagaggtag atacttgtca ctaagacaca gatcaaacca atcagcaaaa
    28501 tcaatttgtt cacatgatat tttttccaga tgcgctttcg ccatcgatgg aattgtccga
    28561 gatatggtct gatccaacgc caaaaactga tcaaagcagc ttttatcttt tctaaaatgc
    28621 tttgaaaatc catttgcttc ttctcctgtc tatttgattc aatcgtctta ttttaccata
    28681 gtgaaagagt gttttcttcc tgcttaagtt gtagttcaat atgttttttt acgttagtgc
    28741 aagtagagta acataagaat gaacagaaaa atgtaagttt tttcttaaat atgttttaaa
    28801 aatggtacaa ttagtctgcg attgcactga aaggagtaca cttgtgaaaa tcacgatcac
    28861 tttacctatg aaccatcctg aaacaacaat tcgcgacttg cttgaaaagg aatggttagt
    28921 tcctagaaag gttcgacact ttttgcgtat acgtaaaaac gtttggatca atcaacaacc
    28981 tgctttgttc catcatgaag taaagggcaa tgaccagatc acattgttat tcgaagaaac
    29041 agattataat tatcaagaag ttcaattagg agatgcgaag cacatccgtg ttttatatga
    29101 agatgagcat ttgattatag tggataagcc tgcaggaatg aagactcatc caaatgaacc
    29161 gacagaaaac agtaccttac tcaatcattt agctgcttat ctcgacacta aacagcaacg
    29221 accttacgtt gtccaccgct tggacaaaga aacaagcggt gccgttttat ttgcaaaaaa
    29281 tccatttgtc ttgccgatac ttggaagaat gttggaacaa aaaatgatct atcggagata
    29341 tcaagccatc gtatggggag aaattgccaa agatatgacc atcaccaata aaattggacg
    29401 agatcgccat gatcggagaa aaagggtcgt agatgataaa aatggtcaga gcgccttgac
    29461 acatgtcact gtcaacaaag tactttctga acaaacacaa gtctattgtg ttttggaaac
    29521 cggacgtaca caccagatca gagttcattt agctcataag ggacatccga tcgttggaga
    29581 ccctctctac caaaatagaa cagctgaacg actgatgctc catgcattag aactgcacat
    29641 gatccatcca tttactcaag aaaaaatagt cggtaaagct ttacctggat tatgggaata
    29701 gaaataaaaa agaacagagt cttatcagca gataatgata agactctgtt ctttttgtgt
    29761 aatttgtctg cttacttttg atgttcgtgt tctgctaaca gcaaactacc gataatccca
    29821 ctttcattcg gcagtcccca acgaacgata tattcactta cttgaggtgt ttccatataa
    29881 ccacccatca attcaacaaa ttgctgacgg attttttgaa ggagatgatc ctgattcatt
    29941 accccaccgc ctaaaataat cttttcaggt gctaacgtca acgtatagtt gatcagtgct
    30001 tgagcaatat aataagcctg aatagcccaa acaggatgat cttgcggcag atcttgccct
    30061 ttgatccctg tgcgtgcctc aatagacggt cctgctgcta atccttctaa acaatcttta
    30121 tgataaggac aagtaccttc ataatggtca tctggatggc gtttcaccca aatatgtccc
    30181 atttcaggat gtgcgatccc tgaaaaaatt tcttcattga tcacgacacc tgcaccgatt
    30241 cctgttccca cggtaaggta aatacaacta ttttttcctt gtgctgctcc ttgcttcaat
    30301 tccccatatg cagcagcatt gacatccgtt gtccaagcag caggaatatt gtagcgttcc
    30361 ttgattgtgc caagaaaatc gaattgtgcc cacccttttt tgggagttgc caaaacgtat
    30421 ccgtaattat cttttgtttt gtcgatacca atcgggccga atgagccaat cccgattccc
    30481 ttcaattcat aacgatcaaa aaattcaaat acctgatcca atgtttcttc tggtgttgtg
    30541 gtagggatac ttaatttttc taaaatttct ccaccatctg aaaccgcaca cacaaatttt
    30601 gttccgcctg cttctattcc gccatacatt cgttttcctc ctcgaatccg attgtccgaa
    30661 tctcataagg ttggattatt gggacaaccg cttgcttcgt tggttcttca agcagattca
    30721 atatgacagt ttttccattg tctttagtta tttccaattt ttctaaatga ctagacatat
    30781 tgaaacctct tactactact ttatcactaa acttgctgcg tttcaaagct gtaattgcaa
    30841 acgtttcact ttttatcgtt aaatattgtt gttttgaaat caatgttcct tcatgatgtt
    30901 tgatttgttg agtggaaaaa ggaatctgtg ctgcgtatgc atgcaaataa gtagagaatt
    30961 tttcttctgg tccatgtagt tcaatgctgt aattgaaccg atgctcacct agacactgtg
    31021 cttctggtgt tggaaaatat ccccaatcgc ctagttctcc cacactgcga agtagcgtca
    31081 ctgcgatttg tccgtcttct gttacttcat attcattcaa accaaagttt ccgactgtta
    31141 caccgtactc ttcatcatga atattgacaa atgcttgctg atgttgcgga ttcgtggggt
    31201 tttcccaact tttagacaca tggtttgggc gcttcaccac ttcaaaaata ctatctgctt
    31261 cgtgatgttc cacatgtaac tttgtaggaa acaagacacg taagcgatga tctttcatct
    31321 gattgtcgag agtcgtttca aagtcgattt ttttactatc ttttctgatt gtcatgattg
    31381 tttttatttg aaggattcgt ttttctttgg atcgttctgc ttttcgataa cgaaattcca
    31441 caaccatctg ctgttctttt tctaaacgct cgtctgcaga aacagggatt tccatttcct
    31501 gtagaatact tatttttgct atttccggtg tatctactaa tacttttact tcagagtttt
    31561 ctttgttact ggataggatt ggctgatcac agaaaggttg tttaaagata tactcatttc
    31621 ctatatcgcc gatatcttca aaaatatgca gattattcaa ctttcgtttg tttttgcgat
    31681 cttccattgt aatggtacca tttttttcaa tcgtcaaatg tagagggccg ttttcgatga
    31741 ttcgtccact ctgatgaatc attgtttcct tttcttctgc tttcgcttcc ccttctacaa
    31801 gcgcgaatgt ttcccaagaa aatgctggca tgttttctaa tggtaaagtc actttgatca
    31861 ttcttgccat atatggcaca cggaaacggt ctttcggcaa atcataacca aattggacag
    31921 tttcttcaga taaaatagct ggtatagtgg ccccactttt tgtttctaca tgatacttac
    31981 gtttaggcaa attttctaac tcttgatata gttgttcagg tattccttca gcgaatcttt
    32041 ttctttctaa ttcgatggtt atttctgctt caccagtttt atccattcct gcagtattta
    32101 caatgacaaa tggaaagctg tcttttggga atccggtcgt atcgattgct gcggtcagct
    32161 gttctaagga atcttgtgca agatactttc caacttcatc tgctttttca aaacgaggta
    32221 tcatttcccg atggacagaa tcgactgaac aaccgcaaat actgtcgtga ggatgatttt
    32281 gcattaatgt cttccaagca taatctaatt gatcatgggg atagtttcca ctaacttcat
    32341 aagccatcgt cgcaagtggt tctgtaatat tttctagctg tcgctggacc ttggtattcc
    32401 attgttttaa gtaaacccga gcagatgctg tattggctaa agtataccag ccatccgttt
    32461 cttgacttgt caattctcct tctactgagc ctaagtcttc tggcacatct ttttgaactg
    32521 cttccagata gtcagtaaaa ttagaatgaa taaactcgta atctggaaac agttcatttg
    32581 cgagatggat tgcttttgat atatcttttt gtaccggttg atgatcaaca ccattcatca
    32641 tcaataagtg gttcgtagag gcatattgtt ctgcatccgc taatttttgc ttccaaaagg
    32701 caagagctgc ttctttttct actggaatct cattcccgtt gctataccaa ttggcaaata
    32761 gcagaccaaa gattgctgtt tgatcaggtc ctttccacca catctctgag tattgggaag
    32821 aatagttttc tgcttccaaa acttgattat caaagccaat tggttttaca ccacggccaa
    32881 acgctgctgc tgaaatacca gcttgtttca ttaattgagg cgtctgtccc atatttccaa
    32941 atgtatcggg aaaatagcct aacatgacag gggttcccca tttacggctt tcttccatgc
    33001 caatcagcat atttctcacg ttcgattccg agctgataag aaaatcatct tgcaagatat
    33061 aaaatggtcc aattctcaat tttccttcat tgattgcttg ttggattgcc tgtctttttt
    33121 ctggccttac ttgaagatag tcatctaaaa taatcgtttg cccatccaaa tgaaaactgt
    33181 tgaaggacgg atcaacttca aatagctcta gtagatcgtc tatcaattca atcagtcgca
    33241 tgtgatgctg ttcgtaagcc atgtaccatt cacgatccca gtggctatga gaaatgatat
    33301 atactttctt tttcatttac gatacctcct acttttctac tctaatatca aagtaatcca
    33361 tgactaattc gcaaaacatc atatttgccc aagaaaacca ttctctcgta taattttcag
    33421 gattgttcac atcgaatcct tcgtgcataa ggtgtgttcc tgcgtcagtt gctacaagta
    33481 aattcaatat ccgctctttt tcagatttgt ctgacgttgt cattccttcc atagctaatg
    33541 caatcggcca aacgtatttt tctggcgtat gggaggatcc aattcctttt gcgtactttc
    33601 cttcatagaa atatggattt tctttactca acaatgttct tcttgtttgc agataatctt
    33661 cctcttgttc agaacaatat cccaagtaag gtgcggcgat cagattgggc acattactgt
    33721 catccatgac tgtggcgttt cccattccat ctacttcata tgcataaatc gtttgccctt
    33781 tttgattaac cgttcgtccg tgattctgaa tcccctcttg gatctctttc ttcaatttct
    33841 gtgtttgctg tacaatttct ttatcatcga gtatcgtttg aaaaatttct tccacataac
    33901 ctaacacgac caccgcaaac atattggatg gtaccagata tccataacgg caagtatcat
    33961 cgctaggacg gaaaccagac catgtcattc ctgtaaaagc tgtttttgca cctcgcccgt
    34021 cattgatcag cgtatcttct tttcttgtcg tgtctcgtac aaatgtataa ggagagtgtt
    34081 catgatcttg ctctgttttg aacacgtcca agattttttt gataccttca ataaaagatt
    34141 gattgaattg atcagttttt cctgtatttt tgtaaagaag ataggccaac tgtattgggt
    34201 agcataaaga atcaatttca tattttcttt cccagatcca atcgttcatt tttgtatgat
    34261 ctgtttggtg gccagcaccg ttagcttctt cgttgaaggc attcgcatat ggatcgatat
    34321 tgatataaaa aaattgcttt ttgactaacc cgctgatcat gtcagctaat tcctcatctt
    34381 cttttgcaat cactaaataa ggacgaactt gtgcagtaga gtctcttaac cacatcgctg
    34441 gaatgtctcc cgtcaataaa aaggtggttc cgtcattttg ctttttgact gttgtcaaca
    34501 gagtattggc aaatgctgct gtaaaattct ttgcccagtc cgcatggata tccccacatt
    34561 tttgtgtgat atcttccata aatttctgca ccgattttgg tatatcttta taagccacta
    34621 ataaaacctt ctttctattt gatatatctt taaagattat acttcataca gccaattatg
    34681 tctacgcttt caaaaaatat ctttttattt actttttcat ccattatggt attatttgaa
    34741 tatgatatat cattaagagg tgtttatatg aatcaaccat tgtaccagac aatatttaat
    34801 gatttgcaaa cggctatttt aactggtgaa ttacctgtag acagccaact accaactgaa
    34861 aaagaacttt cacgtaccta taaagtaagc agaatcactt ccaaacgtgc attgactgaa
    34921 ttagagcaat taggacttat ttatcgcgtt cgcgggaaag gcagtttcgt taaatccgct
    34981 tctccggaac agattcttgc ttctcctaca aaaacacgac ggattctgtt tcttcttcca
    35041 tatgtcgctg atttgtctgt tggtgatttt agcaagggat tgaaccctgt gatgcaagat
    35101 aaacagattg atgtcatgat gacgacgctt gactttctac aaaataaaac agcaaaagag
    35161 ctaatcaatg aatttgacgg attgatttat tatgctcttg atacagaaca acatcttgac
    35221 ttactttttg agctttcatt gaaagaattc cctgtcgtca tattagataa aaaaatctat
    35281 gagttacctt ttcctaccgt tctttccgat aatttccaag gcggtgcgct tgctgcctct
    35341 tatttgatcg aacagggaca ttcaaaaatc gcttatttgt ttggtacgca gactcatcca
    35401 caatccgttc gacagcgtta ccttggttac cttgaagcat tggacaaagc tggtttgact
    35461 ttccacactt cactggatga caaaagcgcg acattagatg aattgctttc ttatatcact
    35521 aagtatgaag taactgcttt tgtttgtgaa aacgatgttg tcgctatcca gaccatgaat
    35581 ctcttgagac agcatggtta tcatatccct gaagattttt caattatcgg atttgatgat
    35641 atccaagcag cagctcttgt tgacccgcca ctgacaacca tcgcacaaga ttttgaacag
    35701 ttaggtaagc ttgcgggaga tgctttggtc acttggttag agacaaaaga tcgaccatcc
    35761 gatagtaaat ttccagtttc attcatcaaa agacaatcaa caaaggagaa ataaaatgaa
    35821 tatcggtcaa atagatacta gacatgcaac agcgaatcag ccaaatttct ctaatgggaa
    35881 ctgccagcct tatactggcg ttccttttgg gatgaattat tttgcaccgc aaactacgga
    35941 tcaaaacggc agctggtggt ttcatcctga tgaccgcgtt tttcaaggct accgtcttac
    36001 ccatcaacca agtccttgga tgggtgattt cagtcatatg ctgtttacgc cgatcaatgg
    36061 aaaactacag gagaacaccc ttttccatgc tcaaagttct taccgcccag aagaaagtat
    36121 attttgcccg actcatctgt cgatctgtca attacgttat ggcatctgtt ctacattgat
    36181 acctagcatg tatggcggaa tcttatctat tgattacagc aaaaatgaca gcggtttact
    36241 tttatccttt ccgggacgcc atcagctctt tgttatagat ccttacacag tggaaggaaa
    36301 aatcacacat tttgctggtt cagaagatcc tgatttttct ttttatttta tattgagatt
    36361 tgaatatcct ttaacaattg atgagttagc tgtttccaac aaaaatagcg actcgatccc
    36421 gttgtatttt gaacagacaa aaaaacaaac tatccgattt gggacatctt ttatcagctc
    36481 ggaacaagca gcttataacc tggaactaga acaaaaccaa agcaaagaga cttaccttgc
    36541 tcacagtcaa gaacaatggc agtcctattt tgatcgtata cagctcacac accatgatca
    36601 acaacaattg cggacgtttt atcataattt atatcgggtg tttttatttc cacaaacatt
    36661 ttatgaaatt gatcctagtg ggcaaaaaat ccactatgat acgactagtc gatctataaa
    36721 acctggtgtt ctctatacaa ataatgggtt ttgggatacg tataaaacgg tttatcctct
    36781 ttattctttg attgctgtag aaaaatacga agaaatgctg gaaggttttt tgaacagcta
    36841 tagagaaagt ggctatttgc caaaatggct gtctcctgat gaacgtggac ttatgcctgg
    36901 gacattgatc gatgcggtca ttgcagatgc tgctgtaaaa gatatccgac gagacttgat
    36961 gcctgaattt ctaacggcaa tggaaaaagg tgctacggtt caaagcaaac atccaaatta
    37021 tggacgccaa ggaacagaag attacttgac atatggctat gttcctaatc actaccacga
    37081 atcagtcaat cacacattag actatgctta tagcgatttt tgtattagcc aagttgccaa
    37141 ggtactagaa gaagaggaaa tgacgaagaa atatcagcag caatcattga actatcaaaa
    37201 tatctttgac tatgagtcag gatttatgcg ttcaaaagat aaagatggca agttcagaga
    37261 accattttca gctaatcgtt ggggacaaga ttatgcagaa ggaagtgctt ggcaaagcag
    37321 ctttgctgtt tatcacgatt tttcaggact gatcggaaaa tatggtggca gtgagagata
    37381 taaagaaaaa ctcattgagc tgtgcaatca gcccccaacg tttgacccag gaggatatgg
    37441 ttttgagatc cacgaaatga gtgagatggc cgcgatagaa tttggacaat tagctatttc
    37501 aaaccagcca agttttcact atccttactt gttcagttat ataggacaac ctgaaatggc
    37561 acagccactg cttaaacagt tgatgactca gaccttcgac gattctccaa tgggttaccc
    37621 tggagatgag gacaatggaa gtatggccgc ttggtatatc ttcaatagtc tgggatttta
    37681 tcctgtcacg cctggaaccg gtgaatatgt tatcggtatg ccattaattg acaaggctgt
    37741 tttgcttttg tcaaatggaa aggaattgac gattgaagca acgcctaatc ggccgcagca
    37801 acaatttatc cataaaatca aacggatgga caaagaatat acgaaattat attttaccca
    37861 tcaagatttg ctgaaaggcg gcacgatctc ttaccaatta gggatcatcc ctcaccctaa
    37921 gaaatatcaa gcaaaagatt tgcctttttc cttatcaaac tataattaac aagaggttgt
    37981 gaaaaagctg tcctgcatca agtaataaga acagccaagc aaaaatagat cctcatattt
    38041 ttcgtttggt tggtcttatt accgcagatg caagcttttg aacaccgttt attgagaggt
    38101 tgtgaaatca gcgttctgac ctgagtatta gagagacaaa tggcaaaata gttcctcata
    38161 ttttgccatt ttttgagcta ataccgaggg tcagctgatt gaacaccgtt tagtggagag
    38221 gtcgtgaaaa agctgtttag tttcgagtat taagaaaaat tttgtgaaaa tggctttcca
    38281 catttttgca taaatttggc ttaataccga gaaactggct tttgaactcc gtttatcgag
    38341 aggtcatgaa aaagctgcct tgcctcaagt aataagaaca gcccaaaatt agatttctag
    38401 acaatttttt ataagttatt tcattacatt ggctttttct tttatgattc tccactgttt
    38461 tctcggtact ctttagggga tctgccgacg attttcttga ataatttaga gaaatacgtg
    38521 gtgttgttgt agccaatctc acttgctatc tcattgatgt tttgattact gtgcaaaagc
    38581 agttgtttcg ctttttccat acgtaaatgg ttcaaataag ctgaaaaact ttttttcgtt
    38641 tcttttttga acagctgtcc tagatacatg acatttaaat gcaggttttc tgacacttct
    38701 ttgagtgtaa gtggttcttg ataatgctgg tgcaggatta cgattacttt ttccacattg
    38761 tcactgtact ttttctgtct ctgatgcttt ttgatgaatg acagaagtag ctgctgaagt
    38821 tcttgcaccg tttttgcctg atggattttt tcgattcctt gtaaatattc ctcatcttcc
    38881 agatcaatca attcccgttg aatctccata aacagtaaaa aactggaata tcgtatatct
    38941 tccggcatca tggctgctaa ctgaaactgt tcaaaaaaat cagtgatcat tttttgagcg
    39001 acttccaatt gtttattttg cagcacgcgt ctgaaacttg aaaaatcgat ggtttgatct
    39061 tttgtttctg cttgtactgc gtaaaaaaca tgctcgtctt tatctccata aaattgatgc
    39121 aactgtagat tgtctttcgc ttgttggaat gtttcaggga ttttgtccaa agaatctgtc
    39181 tcttccccga tactgatcag ccattcctga tcaggaaagt tttcttgaac aaaacaacag
    39241 aagccatcaa cttcatctgc ctccaacaac aacgtgatca atacacggtc tccgtaattt
    39301 cgttgatagt aaaagatttg ttgccgttct tgcaaccatc tattgataag agtatcatga
    39361 gttcttgcca gttgaatcaa tactatccta tgctgcttct cacttatttg tcctattatt
    39421 tcttcttcac ttatttcatc caattcttca ttcaaccatt gactgaataa cagttcttga
    39481 tagatttctt gttgattttt ttgttcattt tgctgatcta accgtgtttt gattttcttg
    39541 aggctttcaa ccaattcgaa cttattcacg ggtttcatca aataattcac ggcgcctaat
    39601 tgcatacctc ctttcaaata atcgaattct tggtatcctg ataaaatcat aaattcaaaa
    39661 ttatgacgtt ctttttgagc cgcttcaata aattccagtc catttatttc tggcattgtc
    39721 acatccgtta ctactaaatc aatctgtcgc tgttcaagta cagctagtcc ttctttggca
    39781 ttctctgctg ttgctactat ttgaaagcct aaactttgcc aatcaattat cttttttaac
    39841 ccattcaaaa tcatgtattc atcatctacc aataacactt gatacacgct catccctcct
    39901 tgaatgtaat agaaacggtc agtccacctg tctcattatt ctcaagcgac atataataac
    39961 tgctgccgaa gctggcacgt aaacgttcat tcacgttttg cagaccgata gaaccgtgaa
    40021 gttccacttt aggatgagac agtttttctt caatctgttt tagccgtttt tcagtcatcc
    40081 cttttccatt atctttgatg atgatcctta cccgtttgcc ttcctgcaag actttgacac
    40141 ttagcgcatt atcgaatcga gtaaaatcaa taccgtgttt aaaataattt tcaactaatg
    40201 gctggatcac aaatttaggt acttcgatct tttccaaatc aggatcgatc ataaaatgat
    40261 aggctactcg attaggataa cgcatttgat acaaatagac atatttttcg caaaagtcca
    40321 gttcttcttt taaagtgatc gttttctctt gattcgtatt gtttcgaagc aaagcggaaa
    40381 acgcatacac aacatctgct aattcttcac ttccttcgct gattgcatac attcggatat
    40441 attctaatgt attatataaa aagtgtggat tgatctgtgc ttgaagcgcc cgcatatgtg
    40501 cgtcttgctg tttgatttct aatttgtaga tgtcttctac aaactgattg atgctatcca
    40561 acatttcgtt gataccgatt gaaagttcct tcagttcata ttccgtgttt gttatgtcga
    40621 tccgcgtctc taaattccct gctgctgttt gatccatggc ctgcatgacg atagatactt
    40681 gctgtgaata tcgtttgaat gttttataaa gaaagataag cagtatattg tctaaaataa
    40741 tgataccaat gatcagcggg gcaagatttt ttcccgtttc gatttttaca ctttttttat
    40801 ctagtacagc taatatacga taatcatcag acagttcttg gtgttgaaca aaattgtttt
    40861 tttccagatc gtcaatcggc aattgtgaat ttttcttcag actctctgtg atgatcattt
    40921 cttgtctttc aaacgtttct ttagctattt tattatcatg gaatgtgtat agtcgatttg
    40981 tcgttccaga aatcatgtat aaagagagtc cattgaatga cgttagattt tctaaaatca
    41041 tatctagttc tttcttttga aaaccaataa aaatacttcc tgactcagct cctccttgtg
    41101 tgataggcaa cttgatataa aaggcgtcta gtaattttgg tgtccccttt tttatttccc
    41161 cacctttgtt ttctctagaa gattcataat actccggtag ttgattcaac acgatatata
    41221 tcgcacttag ttcttcataa tttgcgtaga gatctttgat ttgatttggg aaagaaacta
    41281 attcatcggt actgttttgc tgttcgtata catacatcag atactgatct atgggttttg
    41341 ttaagtaggt cgtcacattt tcgatctttt cggaattccc tacaagctgg tttttgatga
    41401 tcctactcaa ggttgtttta tcattcagca ttctgcttgt gctttgaacg gcatcacttg
    41461 tcatgttttc tgcctgtttt tgattttgtt cccaagtatg gatactaaaa ataacggtag
    41521 cagtcatcgt tacaccgatc atgataaccg cgtatttccg caacagacga tttagtaagg
    41581 ttccttttga aaatagaatc cgaaacttat tcataacttt ccaactgttt atctaattct
    41641 tcacgccaat gtgttgtcat cgtaccattc caaaccgtca aaagaccaat gacaccaaac
    41701 aggatcaatc ctttgaattg ccaagtcacg cctaaaatta taccgctacc aataattatt
    41761 tttagaaaag acgaaaagct ggaaaaaacc gaaataaaac ttagctttag cagattagga
    41821 acagagatcg tatattcact atctaaaatc atactgtatt gataagtagc aaataggcag
    41881 agcaaggcaa aaagtaaaat aaaatcaata gctaaaaaaa tgagcccttt gatttgaaca
    41941 gataaatata aattgtaact caataaagca gtaccagata aaaataaact aaatagcaga
    42001 ttgcctctta aaaaatttct tttatatata ttccagcctc tttttattgt gatttcttta
    42061 tactcgaatc cgtacaaata aaatagttca ttgactgttt tccatgccgc acctaatcca
    42121 aagatgatcc cgccggcaaa tgtatatatc cagaaataca aggttagttt tataatgacc
    42181 cagatccgga taaataactc ttccaaaacc ttccctaaca tatcttctcc tccaaacatt
    42241 aagtttatac tttctcatta tacaaaaaaa ggttgggcaa tcagcacctt gacctgatta
    42301 ttagagaaac aaacggaaaa atagttcctc atattttgtc gttttgtgag cgaataccga
    42361 gggttagctg attgaacacc gtttaccaag agtttgtgaa atagccgctt agtttcgagt
    42421 agtaagaaaa attttgtgaa tatggctttc cacattttta catatattta gcttaatacc
    42481 gagaaactgg cttttgaaca ccgtttattc ggaacaagag gttgtgacac gtcttttgtc
    42541 acaacccctt tgtctttatt cattattatt cttgtcggaa ctcatcatat tgtttttgca
    42601 tttctttcaa taccttatca tagccagcct tgtccaaagc gtctttcaat ttcggtaatg
    42661 tttcatctgg atcaacagtc cctgtattca atccatctaa atattgattc atgacattag
    42721 aaatattact taattctgtt ttgacactgt cagtgttgaa gctgaatcct aaaatcggtg
    42781 aagtttctgc atcagcaatc gattgatcac gtttggcaat catgtcatcc gtaatagact
    42841 cttgtgtata tagaatcttg ttgtttcctg tattccaagc agacatatgt gtatttggct
    42901 gataaccatc tagcaatttg attttatcat ctgaaccatc gactttttcc catgcttctc
    42961 cctcgatccc ccaaacaagc ccattcaata attctggatc actgttaagc agccctagaa
    43021 gttctactga tttttcttta ttttttgaag tatttgatac gacaaaattt gccatttgtg
    43081 cttgagctgt agattttagt ggaacagtaa ttgcttttga gacaagttct tgttttgctg
    43141 catttgtcaa aattgtatcg ccataatcat acggtccttg tgtttctcca cgcattagcc
    43201 aagtatttcc ttctagtgga taatccttat tgctcgttgc agcgtcactt ggaatgagtc
    43261 cttgtttgta ccagctatgc attgtacgta acagtccgat atacgtttca ttatcgtatt
    43321 ggttgatgat tttcgaatca tctccatcca gatcaatagc aaatggtaac gtattcccta
    43381 aaggataatc aaagttccct tggactttga agccttgtcc aatggcaaaa gctgccgtgt
    43441 ttggttcttt ttcatggaat tccttcaaga ctttttctgc atcagcgtaa gattggattc
    43501 catcaattga aagatcgtat ttatctagta aagctttgtt aaaagtaagt acttgttgag
    43561 caaagacatt tccattgact gggaaagcat ataattttcc attgaccaga tttcctttaa
    43621 tatatgcttc atctaaatca ttataagctt tttcagcgta cttaggcgct aattcagtca
    43681 aatcagcaaa ggctcctttt tgggcattgg aaacatagtt gttcgcaaag gcgatatcat
    43741 aattttcccc ggaagaaatg atgacgttca ttttcttttc gtaatcgccc cagccaatgt
    43801 aattgatatt gacttttaca ccgatctctt tttcgattcg tttgtttgct acttccatca
    43861 attgatcgaa attatctggt ttatctccga tttgatacat ctgcaaagtg tccgaattgc
    43921 tagcttctgc ctggtcttta gaaccagaac ctccgcatgc tgctaatgtt cccaacaaca
    43981 acgctgaaac acctgtaaag gctagtttct tccataactt catttttctt cctcctaatt
    44041 ttatgattta tatttttgtt tctttattct tttactccgc cgattgttag acctttgaca
    44101 aaatgcttct ggaaaaatgg atagctgatc gcaataggca acgtcgagat gactacgatc
    44161 gccattctgg cagattctcc tggaactgag gctaatccgc ctgtcaattg gcttcctgct
    44221 cctgaatttt gtgtcagata ttgaatatta ctttggattt tcatcaaaag atactgtagt
    44281 ggaactagct tatcatcttg gatgtatagt aaagcattga accagtcatt ccagtaaccc
    44341 aatgcggcaa ataaactgat tgtcgcaata cctggaacag ctaacggtaa aacgatctga
    44401 acaaatattc gcagttcgct agctccatcg atccgtgccg attcaataat cgaatcagag
    44461 accgaacgtt taaagaatgt gcgcatcaca ataatattga agggactgac agccattggc
    44521 aagatcaatg cccaaatcgt atcttttaac tgaagaagat ttgtcataac aagataattg
    44581 gccaccatcc ctggtgagaa caacatcgta atcaaacaaa aaacggtaaa aaaacgacgg
    44641 aatggaaagt ttgaccgtga aatcgcataa gcatataaag aagtagccgt gctattgatc
    44701 agtgtaccta aaacagtaac aagtacagtg acgaaaagcg cttggaaaat tttatcctgc
    44761 atctggtcga acaagtacgt ataaccaaat atactgaact tttctggcca aaaactgtac
    44821 ccgtgagtcg acaatatgga ctcatcggta aaagagatgg cgataacaaa tataaatggc
    44881 aaaatacagg aaatagcaaa gagtgcaatc attatattag agaaaaaatt agccgtctta
    44941 ttgaaagagc ggacttggac tctctccact ttcttttttt tcattttttt cctccttaga
    45001 ataatgcaga atcgctatca aaacgtcggg cgatcgtatt tgtgatcatc aacaagacaa
    45061 agccgacaac tgattggtaa agtcctgcag cagccgtcat accaaaatct cctgtggatg
    45121 tcaggccatt gtagatatac gtatccaaaa cttgagtcac atcatataat gcaccggaat
    45181 tcctaggaat gttataaaac aggccaaaat cagctcggaa aatgtttcct acggctaaaa
    45241 tcgttaaaat cgtcattagt ggaataagtt gtggtatcgt cacatgtttg atctgctgcc
    45301 atttgctagc tccatcaacc atagcagctt cataataagt cggatcgatt cccataacag
    45361 atgcaaagta aataatgctg ttataaccaa tccctttcca tgtaccaatg aacaccaaga
    45421 taaacggcca atatttcggt tcattatacc aattgacagc ttctcctcca tgtccagtga
    45481 tccactgatt gaatattcct ttgtcaggac ttaaaaaagc gtaaacaaag taactgataa
    45541 tgacccaaga tagaaaataa ggtagtaagg acatcgtttg ataaacttta acgagtcgtt
    45601 tatttctcaa ctcgctcata atgattgcaa atacgactga gatcagcaga ttcaaaagga
    45661 taaatgctac attatataaa attgtatttt tagtgatgag aaatgcttga tccgaagaaa
    45721 ataaaaattt gaaattttcc caacccaccc aaggactttc cctcaagcta gccaagaacc
    45781 catctgctga aatatgaaaa tttttgaatg ctacgacatt cgccattaca ggtatgtaaa
    45841 agaaaaaaat catccaaagc atacccggta cagccatcag gacaagtgct ttataacgcc
    45901 atagattcat aaaaaaatga ttgaacccct ttcgtttttt catctaaaaa cccctttcga
    45961 ttcattcgca acgtaattat agcgctttca ataatgagaa taaataaaca aagtataggg
    46021 aaaatgaaac aaagtatagg agaggttgtg aaatcagcgt tttggcctga gtattagaga
    46081 aaaaaacggg aaaatagttc ctcatatttt gccgtttttt gagctaatac cgagggtcag
    46141 ctgattgaac accgtttatc agaggttgtg aattcagcgt tttggcctga gtattaggga
    46201 gatcgtgtcc ttactatcta actctgagtc acaaggaaca atggggactg taacaaaagt
    46261 cttgtcacag tcccttattc cgaacaaacg gtgttccaga agtagcttct acggaaataa
    46321 gccgaaattt cacaaaaaag ccatccgaaa gtcagacgga caagtctgct tttcagatgg
    46381 cgctacaact actctgctta ttcttttagc tatccattca attatttttc tctcacttgt
    46441 tctagctctt ctttggtcat gggtcgatat tgccctttat tcaaatcttt aggcagccaa
    46501 aattttccca tacggattct ttttaaatat aagacttctt ttcctactgc tttgaccatt
    46561 cgcttaactt ggtgaaactt tccttcatgc aaaatcagac ggataattga agtttctgtc
    46621 tcttgatcta cttgatcaat ttggagtttt gccggcaatg tctgctcatc gccatcaata
    46681 atcagtcctt ctgcaaataa acggatatct tcttctgtca ttataccgct aacctcagct
    46741 agatattctt tctccacatg ttttttaggt gatagtaact gatgggcaaa caccccgtca
    46801 ttcgttaaaa tcaagaggcc ctctgtgtct ttatctaatc ggccgactgg aaaaagatct
    46861 tcccgataat cctggtcttc caataaatcg attacggttt gatcatgatt atcctgagta
    46921 gcagaaatga ctcctgcagg tttatgcaaa atgtagtaaa aatctttttg atacgtaatg
    46981 atttctccta aataagtaac cgcatcttcg aattcattta cttgcgcttt atcgcttttc
    47041 accacttgtc cattgacttc gatcgttcct tttttgatta atcctttgac ttctttgcgg
    47101 ctgccaagtc ccatatctgc taaaaactta tctaaacgca tgcgtttccc ccatttcaaa
    47161 agagcatcaa tctagctctt ctgattcact tattttattt ttaatttatg tcgtaaacgc
    47221 gctattcctg gtcctagtag tctttctgcc aagcggattt tcaaagctaa ataaccatac
    47281 actaaagccc ctatacctgc tactacaaga atcaacaata gagactggaa tttgctatct
    47341 tcgtttaaaa aagcaccaaa aatcatcttt gtgatccacg aagccaaaag cataatcaag
    47401 gtaagaataa agatcagcaa tgtcctgcgc cagacaaaac ttggtttaaa gcgggctact
    47461 tcatggattc tctttaagat caaggtacaa gacacagcaa atccgatcat tgtcgccaat
    47521 aaagggccgt atacttcaaa taaacgaatg gctgggtatt gaagaaggag tttcactaga
    47581 aacccaataa ccaaataatt aattgccgcc ttgttttcaa acattccttg cagcatgttg
    47641 gaaactagca tatatagtcc taggaagagt cctacaaaac ttgcttggat cagtacatta
    47701 cttcctagag aatccggtgt ataaaataat gtatttagcg gataggcaag taacataaca
    47761 ccaaatgtcg ccggaaacat aaaaaatgaa aacaactgta aatttccgct tgtcaatttt
    47821 gccagaccta ctcgatcttt caacgtaaca gcttctgtaa tcaacggtaa cccagtagac
    47881 gcgatcgatg ttgccaatgc aataactacc atcgtcaact tatctggatt ggcactaaaa
    47941 atcgaaaaaa gatccagtaa ctgtgcattg gaatactcgg tggatgcaga catgatcttc
    48001 ataaaagtga actgatcgac taatttgaag atcgttaccc ctgaacccac aataataaac
    48061 ggaatcgctt ctttaacggt atctaacaac aattccttcg ttgcaatatt tattttgttt
    48121 tcgctgtagt gaataaacgc cgatgtatac gcttgatgtt tcttcaaaaa atacaaaagg
    48181 acaagaatac ttgctagcat accgataaat gccgcgaaag ttgattgcgt gaccgccgtc
    48241 acatagtcac catccatgac tttcatgatg atgaatgtag ccaatagcat ataaaaaata
    48301 cgtgccacct gttctacaat ctgcgacagc gcataaggca tcatttcttg attgccttgc
    48361 aaataccctc gtatcacact catacaagga aaaaccaata cagcgatact caaagaacgc
    48421 atcgttggaa tcagttcttc tccgccacca gaagcatgag ctagccaagg agaggcgatg
    48481 tacatgaaca aagcaaacaa caggcctaac ccgcccatca tctgtaatgc acggataaat
    48541 aatcgtcgtg aagtgccata ttcattcaat gaattatagc gtgcagtttg ttttgcaatc
    48601 gcagcaggta ttcctgctgt agagatcagt agaaacaatg catatatatt gtatcccata
    48661 ttgaataatc cattggcagc cttagcattt tcgcccatcc aagcatacca gggaatgata
    48721 tagacagcgc ctagcaatct tgaaatgata ttactggcgg tcatccaagc agagcctcgt
    48781 gccatttttt cttgcggtgt taattgatct aatgctggtt ttctttgatt atccatcggt
    48841 cagattccaa ctttctacaa aacattacta tcattttaat tggtaaaaca gaaactggca
    48901 atcgatttta tataactttt ataagaacaa ttgttttttt gaattcggtt tcgttttttt
    48961 ggtaaagtaa agaaatatac agccttttat ggctaacatt tataggagat atcaatgaca
    49021 caagaaataa aaaaactacc cgttatattt ttaggtcttt tctttatcac agttggattg
    49081 aattggttct tgctccctca cgatatagct tccgccggag tgggcgccat cggacattta
    49141 gttgaaacgg ccttttctat ccaacgctca gttactgttt ggagcatcaa tcttatgatg
    49201 ctgcttctag ccgctgtcct attaggaaaa tcagtatttt ttaagactgt agcgggaagt
    49261 ctgctttttc ctgttgtttt agagattgtt ccaaaagtgg aaatgatctc ctcacatttc
    49321 ttttcactga tttcaggaag tcttttgttc agtcttgggg tttacacatt gtacacagtc
    49381 ggggcctcaa atggcggtat aacgataccg ccgattattt tccacaaatt ttttcggctt
    49441 ccaatgccgc aaggactttt acttaccaat agtcttatcg tctttttgaa ttattatgtt
    49501 tttggattgt tggagacact attcgttctc ctatctatta cagtcagttc attgtttatg
    49561 aaaatactca tccgcttgtc ccctgtgtca agaaaatttg aataaagctg gattttgtca
    49621 tagcggaaac aaacgatata ttaaaaagag tgtgctataa taaaccaaga aattgaataa
    49681 agcgagggat caatcaatga gcttctcttt agaagacatc cgtcatttac tattaaaaga
    49741 aaatctatta aaagaatttg tttcaacaag aggctggcat cttgatgtac cagaaaaagc
    49801 tgaatttctt cagttaagtt atgattcaag aaaagctgat gcttctactt tgtttttctg
    49861 taaaggaatg aatttcaaag aagaatattt ggattcagca atcgaacagg gtattcaata
    49921 ttatgtatca gaacaaccat acgaaaattc agcagtagga atcatcgtaa cggatatccg
    49981 taaagcaatg gcgcttcttg ctatggcttt ttacgactat ccgcaaaata aattgaaagt
    50041 gatcggattc actggaacaa aaggtaaaac aactgctgcg tactttacaa aagcaatctt
    50101 ggatcacaca acaaataaaa aaacagcatt gctttctact atgaatacaa cgttagatgg
    50161 caaaacatat ttcaaatccc atttgacaac gcctgagtca ttagatttat atcgtatgat
    50221 gtcagaagca gttgaaaatg gtatgactca tctagtgatg gaagtttctt cacaagctta
    50281 caaaacacaa cgcgtatacg gcttgacttt agatgtcgga atcttcttga atatctcgcc
    50341 tgaccatatc agtccgatcg aacatccgac atttgatgac tatttctatt gcaagcgaca
    50401 attgatcttg aattcaaaaa cagttgtttt aaatcatgaa agtgactatt ttgatttact
    50461 tagggaaaca gccgatctat tccagattcc aacgatcact tatggtcgtt cggaagaaag
    50521 caattatcaa gtgatccgtt cagataaagg tactcacggt tttactttat cttctcatga
    50581 agatcgctta gctatctgcg atactgctta tgatattttg ctggctggag gattcaacca
    50641 agaaaatgca gccagtgcga tcattgccgc agcactaaca ggtgcctcca gtcaagatgc
    50701 acaagacgga ttaaaagaag ctcgtgtacc aggccgaatg gatcaattga tccaatccaa
    50761 tggagcgcat gtctatgtgg actatgcaca taattatcta agcttgaaaa cattgctgaa
    50821 atttgccaaa aatgaacatc cagatggccg tgtaattgtt gtattaggca gcccaggaaa
    50881 caaagcaatc tcccgtcgac atgattttgg aaaagtgcta tcagaaacag ctgacatcgc
    50941 ctttttgacg gcagatgacc cagcatttga agatccgaaa aaaatcgcgg aagaaatcaa
    51001 tgaagcaatt actaatccag atttgatcgt tcattatgaa atggatcgtc ctgaagcgat
    51061 tcgacgcgct ttagcagaaa gcgctccgca agattcagtc gttattgcgg gaaaaggcgt
    51121 ggatccctat caaaaaatca atggtgtaga tgaaccttat gaaggggatt atgcaatcgt
    51181 gaagcggttg attgaagaat aatggtattt atatactagt ggtttcccat ttctaagaaa
    51241 aaaagggact gtgatttttt gtcacagttc cttttttctt agaaatcatt ttaacttttc
    51301 actagctaat tctgctgcct tttctctttc ttcatttaat aatttattat catagaattt
    51361 gataaatggg aaccagataa tgaatgcgat gattgcacaa atgactgcta acacagcagc
    51421 tttccaatca ccaccactac caacaaatgc tccgatcccg actggtgaag gccacggcat
    51481 ctgtgcaagc atcggtttga cgatttccag ccgaatggca aaataagcga gtgtagcaga
    51541 agccatcgga gctaagaaaa acggaaccgc taaataggga ttgtagacga ttggcatccc
    51601 gaaaatgatt ggttcattga tattgaataa tcctggtaca agtgaggctt ttcctaacac
    51661 tttcagctga tcagatttcg cgaggaatgc aataaagatg atcaatccta aagtcgcacc
    51721 tgatccacca acggttacat aagaattgtt gaattctcct gccaacggat aatttgcgcc
    51781 ttgtgcgtta gctgccatat tagctaatac gatcggggtc aagaaagaag tgatgatatt
    51841 cgctccatgg atccctacga tccacaatgc atggatcaag aaataaatca ccatgacacc
    51901 aagccatgta ttcgtcaact gcgtaacaaa cccaaatggg atagcaatca ttttgaagat
    51961 atccgttcct agtgcaacta ataatccatt gatgatcatc accacaaacg caatgacaaa
    52021 tgttgggatc agagcagtga aagaacgaga aactcctggc ggaacaacat ctggcatttt
    52081 tatgacccaa tttctcttga cacacataca atacaattcg accgcaataa tcgacataat
    52141 aatagctgta aagattcctg aagttcctaa acgttcgaca aaagagccca tcctaatacc
    52201 atttactaca gtttctgtct cattgataga agcaatcaag ctgattttac catcagtcat
    52261 gatcaattca gggatacaca taaagaatgc aaaaacagat agtaatgccc ccgtgagcgg
    52321 attaacattt aatttttgtt catctcgttc aattgacgtt aattcataag caaacacaat
    52381 ggcaaagtaa atagataaaa tccccatcgt cattgtattg acgatcatgt acaagtcact
    52441 aactttgaaa aaagttgcat taaaaaatcc ttctaaaaat gggaacggta atggcaaaat
    52501 atttaaaacc aaaaacatcg agcctacaat cgtgaaagga atagaagcca tccccgctgc
    52561 catgacagcc cgaacgattt taagttgcgc aattttcccc ataggtccca tcaggtattt
    52621 ctgcaaaaaa tcaaacatta gttattctcc tttcctaaat ataacgcttt ttcatattgt
    52681 ttaatacgga tatactgttg gtcttggttg agtgaaattt tctttaaacg atactgtata
    52741 aatgcactgg caaaaatacc gcttacaaca agaatgaaaa caaataactg tcctccattg
    52801 ttatttgcca taaaaggata caagaatgta aatcctgagg taaacaacac tggaatcact
    52861 aataaattaa agacactctg gaacaaaaaa taccactttg tccatggaac gttcgtttgg
    52921 tgttttcgat aaagctttac ttgttctcct actgcaggca aaatagctaa aatcagaatc
    52981 atcggtaaac tacttcctaa acttttagct gatagaagca gaatcatcca ttgcatgttc
    53041 atgaaaaaga aaaaggcagt caggtaacgt acgattagat aacgattgaa atacatgttt
    53101 ttcaaactaa gttgcttttt ttctaattcg attttccttt ttactgtatc ctgcacaatg
    53161 atccttcctt tctatttatt tttttgatac aaataattca tttcctgtgc aacttccaat
    53221 aatgtcatcg tcgtcatcag atgatcttgt gcatggacca tgataatttc catttctatt
    53281 tttgtcccgc tggcatattc tttcagaagt tgagtttgtg actgatgcgc atgaagaatc
    53341 tcttcatttg cttgtcgcaa cttctcttct acttcttcaa acatctcttt acgcatcgag
    53401 cgaaatgctt catgtatcag tgtccgtgca tttccgctat ggaaaatgat atcaaaagaa
    53461 gtcacttgta gtgtttcact gtttattttt tcagccatct gttttcctcc ttattcgatc
    53521 agtttgataa atttactgct gaaattctca aaaataggtt cagctaagat ttcctgctgt
    53581 acttttagct ggtcaactaa cctaacgatt gctttagtca cgaccgtaat tccttcattt
    53641 tcgacataag aaggcgaaac taaaaaaaca aaatgaattt cttgatattg atcccactgc
    53701 atcccagaag gaatcaatgc aacggctacc tttgtttcga ttccaactgg aacagcggga
    53761 tgtgggactg ccactgtatc actgaatatg atttgtccca tattttcacg ttgctggatc
    53821 tgctttcgca tttctcttat atatccttct tcttcattta tgctcagctt ttgcagcaaa
    53881 tcatgaagaa tttcttcctt tttcggttcg tacgtataag tcttgaaaaa tttttcagac
    53941 aactgttcgg tgtaaatctg ctttttttgc tgtagagaaa atgctggtat cggtctatct
    54001 gaggaatgat agggtataga ttctccaact acctttcgta ttttacgaac atcatcttca
    54061 ttcaaaaaaa tactgacatg taaaactgga attttgaaaa acattgtcga aagatcaata
    54121 gaagaaataa tcaggtcgat tccttttaaa gttgtttcat tgatctcata atagcctttt
    54181 acacttacca ctgtaatatt tttaccgaat tcactgacta cgcgattctt taatagttgg
    54241 gcactgccgt aacccgttgc acagataatc aatgcatgta gtttatgcgc agctctttct
    54301 ttttccaatg ccgccatgag atgcaaagcc aaataggccc attcatcttc attgatggta
    54361 tagtttttca aagccggcat gttgctgaaa tgccttttta ctgcgtcaaa gactttggga
    54421 ttttctttct ttatctcctc agtcaatggg ttctcaatgc gaatacctcg gctcaatcga
    54481 atcatcatcg gtgacaaatg atcgagtagt ccattgaaaa gctggagatc ctctactaat
    54541 gaaaaatgaa attcctgaga caatcttttc agaactttcg ctaattcctt tgatagttcc
    54601 tgatcatttt gattttcttt gtgattcgac ttagccatga gatgtaatgt caaataagca
    54661 atttcttctt cgggaaacga tacacctgcg attacctcaa tacgttgaac gatccgctgc
    54721 gccacttgat actctactcg cttagaaact tcttgttcga tgcctaattc cttgatttca
    54781 aacccttctc ggagccgttt gatccccaaa gccaagtgta aagtcagatt ctgtatgata
    54841 aaatccgaaa cttttaactt agcttctctt gtttcatcga gaatgataat gactagctct
    54901 tcaaaactga tgtctgggaa aaaacggctt tgccctaaat attctttcaa tgaatttcca
    54961 taatggtttc caaaaaaagt atccatgata aaatgccgtc gatttctttc ttccccttcg
    55021 atccatgtcc cttgaccatg cttagaaacg atttttagtg aatatggaat caatcgctcc
    55081 ttgatttctt gcatgtcctt tgtcaaactg gaacgactga tataaagctc ttctgccaaa
    55141 tcatccataa aaagaatggc atcttccaaa agcaattggt tcaatatata cttttgtcga
    55201 tcttcggact cataaaatcc ttgcggttct ctagcatatc caggtactat ttcttgccga
    55261 ctcaaaaaca agtcaaatgt cagtctttgt aaaatatgca gttggtagcc ataacctggt
    55321 ttagcaatga tcttacctcc gtttttttct actaactctt tgatccgctg caagtaatta
    55381 cggattgtcc gatcagataa taacaattca gaagctaaac gttgactggt gacatactcc
    55441 ttcttgtgat caatcaaata tctcaacagc aatttttcct tctgtttcat tatcatccac
    55501 tcctattcca tcatatgttc tcttcgatca cctctgctaa cttctggatg cctgtaggga
    55561 ttgggacata cgcttggaaa gggatactaa caacaggctt tccaacagat tctcctaatt
    55621 ttttgaattt atccaaaaac atcgtcgttt gcgggctgat cagaaataaa tcaaaatcac
    55681 tattcttaat catattatcg ccttctgtag ctgaaactgc atctacgagt acctcttctc
    55741 ttttttgctt aaagaaatcc gttgtctttg aggccatcat cgaggatgac attcctgccg
    55801 cacaaataat caatgctttt ttcataaatc aatcactcct tttattttta taaaccaagc
    55861 atatcttgta agcgttttct attcaaaata tatatttccg tagcattgcg gaaaaaatgt
    55921 gtatcatatc ttgaataata atttctggca ccgtgatata ctagtgatag aattttttca
    55981 ggaggggatt tagtgagtat cacagtgaat attttgtata caagtacaaa tggacaagcc
    56041 agaaaatttg cagaagaaat ggtcgaaaga aacattgtca aagcgattcg tgcagaagaa
    56101 ggaaacgaga aatatgacta ttactttcca ctagaagatc cagaatctct tttactgatc
    56161 gaccgttgga aagatgaaga agcaatcgaa aagcatcaca aatccgaaat gatggctcaa
    56221 ataaacgaac tccgtaaaaa gtataaatta aaaatgaaag tcgaacgttt cactgattta
    56281 ccgtaaaaag atacacatgg aatgatagca atttatcatc catgtgtatc ttcacttttt
    56341 ccttattttt tattcgatct catctaatga ttcaaaccgt gtttttctct tatttttcgg
    56401 ataagtattt cagtcacccc aatatacatg attcctaaac ataccccaag gatattctca
    56461 aaaatgcgga tcgttactgc tcctggaacc ccgaataaac tggcagtgat tgccaaagca
    56521 ccaaaagaat taaaaactgt tttatatcta taggtagaac aaacacctaa agctagacca
    56581 cctaatatac cgacccagtt aaaaggaata aattggctga taccaataaa taaaacacat
    56641 ccaatcaatg agccaatgat tcggtctact gctcgttctt tgaaaccaat cgacatcaat
    56701 ccatagctag atacaataga agaaaatgca aaccctgccc acatcaatcg ctgaaaaggg
    56761 acatactctc ctgcaacgat caaaagacta atgccaaatg catagatgag catccaaatt
    56821 ttttcctgcg aatacatgcc tttcaaaaaa atctctttaa acaagctttt gtctttgttc
    56881 ttttctcgat gttttctgta aaggagaact gaaaaccaac aaaaaaacaa aaataataag
    56941 ctacttgttt gtgtaaagaa attcttgttc aacgaatctt taggtaacga ataaacaata
    57001 aagagatatg aaaagccgta caaagaagca ttccccattt tgggatcact agcggttgcc
    57061 attaatatgc tgcttagtaa aataaaatga atcaacatgc ccataactga ccatttgatc
    57121 agctggacat acggtgctac taatagtgag aacatgacga ttgctaaacc tatgatcgaa
    57181 tgggaaatct tataaccaaa gtcaacaaaa cgaatactca tcaacataca gaataaaacc
    57241 acagcgtatg gtttatgctt cgattcaaat aatgttgtaa ttataatgat aaaacaaatg
    57301 gcaaacaata cgatgaataa tgatcgtaaa aacaatgaac aaatatacat gcacttttct
    57361 tttttagaag ctgcttctcg tattttttgt tttaaaataa acggatctag ttgtagagac
    57421 tgataaaaat ccacctgttg tcgtcctttc tttttacttt tattttttac agtcatctat
    57481 gacaggttgt aaatactatg gaacatcata tggcgttgtc attttcttgt caactatttt
    57541 tcctattcat gtttttataa aaaaacatat cgttttcttg tatgattaaa tcaccacaaa
    57601 ataaacaact gagagaacga tatgctttat gaatggttct atcaaaaaaa ttctgagatc
    57661 aatagacaaa aatttgatga ttacagaggt ctcttacgaa accttacaga agaaaaaaac
    57721 attgatcgtt gctgcagttc tcttccctgc tccatgtgtc tgtagaaatt gtggttctgc
    57781 tgtggtagat ggaaatagga aattaatggt ggtgaaaaac aagaagaagg aaaccattgt
    57841 ccactttgaa taatataatc atatgccaat ggttatacgc ctaaaaaagc agcgctatac
    57901 ctgtaaaaac tgtcgaagcc attggaacgc tcaaagttat tttatccgtc caaggcactc
    57961 gatttcaaat catgtcagac ataaaatcac ttctttactg actgaaaaag tgtcgttatt
    58021 ttttatttcg aaaagttgtt aggtatcttt gacaaccgtt attcgcacat tgaaagagtt
    58081 gagaagctat ttaccaaagt cttccaaaag aattctgtct tgagtgttga gggttgtgaa
    58141 tttcgttctc acgtttccgt tgaggataaa ctgagtttta tttccgcgga tggcgagaca
    58201 gaaaaattaa tcgagaaaat ttacctacac aaaaaattcc tcgattaaca aactatttcc
    58261 ttagctgcac taatcctaaa gaaatagaat tcttagttac agacatgaac gccacctact
    58321 ttcagctcac caaacatgtt ctaccaaatg cgaaattggt gattgatcga ttacttggtt
    58381 tttccacgcc tttcaaggag gcgtaacctt tattcacgag ttggttgaag ctttccgaga
    58441 caaaagaccc gacttgtttt tctccttatt gacaaagagc cattaaaact agagaaaaaa
    58501 ttacaactga tcgctgatta tttgtagaaa gaaaatcaaa gtattaccca ataaacttga
    58561 gtcattaggc aaaaaacact gcgaaactca agaatgattt tcgcagtgtt tttgtatatt
    58621 ttttattaac tagtattact acaaaggttt atttttcact tctcaacgca gcacaaaatt
    58681 gtctttactt atttactggt tgggttcaac cttctctact ccgatactaa tatttgtttg
    58741 tatacccctt ctaaaatcgg tagtttccat tcaattgatg ggtactagtt gattttaaaa
    58801 actatgctta ttcaattttt tattttagct catatatttc gtttctttct aaattttata
    58861 ctgatgaaaa caagtagcac acccaatatt gacaatataa actggctaat gatggtttct
    58921 ccagtttttg gaagatgctt atttccactg cttgttggat tgtttcctct tatatctgag
    58981 ctatcagcaa cttttctatt ctcttttgtt aaaaagatcg ccacttcttg ttctttttcg
    59041 atcttgaaag ttactggtgt cgcatccaat tcataccccg ttggcgcttg agtttctacc
    59101 agctgatatg ctcctggtgc taagccatct atcgccagtt ttccatctgc tcctgtggtt
    59161 agacctgact gcagaacggt tccattggca tcttgtaact caaaaacagc tccttgcagg
    59221 acttctccgc tttggtcatc gatctttgtc aacacgacac cgcctggtgt aagtcgattt
    59281 tctttcgtca attctaccac cgctgtctga cttctttcga tctcaaactc gattggtgtc
    59341 gcatccaatt cataccccgt tggcgcttgg gtttctacca gctgatacac tcctggtgct
    59401 aagccgtcaa tcgccagttt tccatctgct cctgtggtta gacctgactg cagaacggtt
    59461 ccattggcat cttgtaactc aaaaacagct ccttgcagga cttccccgct ttggtcatcg
    59521 atctttgtca acacgacacc gcctggtgta agtcggtttg ctttcgtcaa ttctaccacc
    59581 gctgtctgac ttctttcgat ctcaaactcg atcggtgtcg catctaattc ataccccgtt
    59641 ggcgcttgag tttctaccag ctgatatgct cctggtgcta aaccgtcaat tgccagtttt
    59701 ccatcttctc ctgtagttag accggtttgt agcgtttctc cttctcggtt ctgtaactca
    59761 aaaacagctc cttgcaggat ttccccgctt tggtcatcga tctttgtcaa cacgacaccg
    59821 cctggtgtaa gtcggttttc tttcgtcaat tctaccaccg ctgtctgact tctttcgatc
    59881 tcaaactcga ttggtgtcgc atctaattca taccctattg gcgcttgagt ttctaccagc
    59941 tgatatgctc ctggtgctaa accgtcaatt gccagttttc catcttctcc tgtagttaaa
    60001 ccggtttgta gcgtttctcc ttctcggttc tgtaactcaa aaacagctcc ttgaaggact
    60061 tcaccactgc cttcagcatg tttaattagt tcaacaccac ccgtatcaag gatgttttca
    60121 atggttaacg tcacttcttc tatggagtat tcatttataa aaacatcatg taccgtcgca
    60181 tctaaaagat acccttccgg tgcttctgtt tctcggactt gatagctacc tacaggaagc
    60241 ggttcactta aaaattctcc gttttctgcc gttatacctt cttgtatcac ttgtgaatcg
    60301 cttgataaaa tttcaaattt tgctcctgcc agcctttggc cattctcatc agttttaatt
    60361 actttaatac gcccatcgat tttccttgtt cttacagtac tcgtattcaa tcgattgtca
    60421 ctattcacaa gcgttgcaaa gtttaaaatt tgatcgccga ccgcatacgc ctctacattg
    60481 accttaaaag agagggtaaa acttgtcgga ccaccaatcg tattattcgc actgaaacga
    60541 actattccat tattgacttc ggcatcaatg aaagagggaa tatctgatag aaatgacaca
    60601 aattccatgc cttcttccaa aacatcttca ataacaagcg tatttcttgt tccagaaaac
    60661 atcgagacat gcagagtata cgttagttca ttttcattga gattgataac atttttgtcc
    60721 acactttttc ttaaagagat tgccggaaga ttactttcag ggattctcaa gcggtagtct
    60781 cggctcatta cctgattatt gtaggtcata ctcgctcgat tccgagaaaa cccatcctct
    60841 tgtcttcctt cattgaacaa gtcgacatcg gtcacttcaa gagcatattc aataaaatac
    60901 gattgaccct ctgctagatt accaaagtcc acaacaagtg tattcgtttc cttattaaaa
    60961 gatactttgt ccacaaattc ctcggaaaca taatgagttc taacgtttgc ttcacctgga
    61021 ttcgttactt ctgcgatccg aaccccacct gaaataggtt ctctatttcc agtggaactc
    61081 catgtagtcg gattcggtgc caaagttgtt ccttgcggta gtacatcggt aaccactaca
    61141 ccgtcttttc gtgatccttc ataatttacc tgcaaaataa atttattact gttggtcacg
    61201 tcttgcccgt caatcagcag attcccaaga tttccttggc tgtcgatttc tctagagcca
    61261 tagtataatt tcgaaaaaat gggtcttgat gaaggaatag gcgtaattga aaattccgtg
    61321 tttgctgctc gctcagcata agtaagactc acttgaaagt cattatttgg ctcagtaccg
    61381 cctgattgaa agaaagcaac ttcaaacgtg atactgaatg tatacgactg agcggcttca
    61441 tttaatcctt cataatcaaa ggtaaatgga aaaacaacgt ctgtgccttc ttggtaaaat
    61501 gccagtggct ttaaaggtga atcatcagcg acctccactc taatgaactc aattaagcca
    61561 atcgatgctc taggaactcg tacgaccatc tccccatatt cttcaagaat atcgccagcg
    61621 cctccttgaa tgtatccctt taacgtttgt gtatgcctgc tcggcaaagt ggggcgctca
    61681 gcagagatgc cgatgtcata attcaagagc tcctcttgtc tttcaatctg agattcctgc
    61741 gttatagatg gctcagatga tctggcttca ttaaaagatt cacttaagct ttcttctggt
    61801 atattaaaag attcacttgt gctttcttct ggtacattaa aagactcact tgtgctttct
    61861 tctggtacac tgatttctat tgagaccgta tttgattgaa tatcaccgct tcttgcggtc
    61921 aattcgtatt tacctgaatg ctgggaagaa taagtaatca gacgttcgta atcattgagt
    61981 tgcttcactt ccccttcaat caaatcctca ctcttatcaa tgaccaatgc atttagcagg
    62041 tctggtgttc ctctgactcg caactggaac tgctcaccca aagcagcctc ctcttgatca
    62101 acttcgatcg tcagcgaacg ctctggctgt tctgctaaag actcagctag aaccgttatg
    62161 ttcccaaatt gattgatcac aataagcata actagaaaca tacttaacag tttatgaaat
    62221 ttgttcctca ctattactcc cccttataat tttgactaaa caacaaggta cccgataatt
    62281 ttctaaaaag attccccaac tcaaaatggc tgcgttacct ccctcgtatt ttcggttcaa
    62341 ctcaagcgtt gcaatgtaag ctgtaaacaa agctaatgat tgccgattgt cttctgttga
    62401 ttgattcgat agctttgtat gacttttagt tgtccgtgtg gcttaaccat aattatgatt
    62461 tcacgattcc tcctgccagt gccttgcaca agctggagcg taaccctaat agttattttg
    62521 ttaatgtact tatatacttt tatacttttc cattagaaac aatcactaaa tcgttgatac
    62581 caaggtcaga ctctagaatt tcatcagtga gtccctgtat tggttaacct tcatcaatcc
    62641 caaaaaaata tatcaatgct tagcatcaaa atgaatatat agtttagaat acttgggatt
    62701 catcgataac tgatcgctta tttggccata ttatttggca cttggttcaa ctaaacgcat
    62761 ttaggatgtt ccttcattct cgtcatggat gttctcaaac cgtcattact aataaactgt
    62821 ccaccgaatc gatggttcat ttcttgcatt ttccacgtcc aattactctt tttgctcttt
    62881 atttgggcgt agtttcactt tcttaacttg tatcgtcttc catcaactcc ttaatcatct
    62941 tcttagcttt attggctcgg tttccttgta aaaggtatct acaaatagtg acaatctgta
    63001 ttaaatcttc atcattttct gtaatgtcaa taatttctat attctgtacc atatattgca
    63061 aagggtttca ctaagttcat aaccgaagcg aattaaacaa cttttgtata gaataactac
    63121 cttttctatt tttccattgg taattctatc tattaattgg tttaatcctt ttgttgtagt
    63181 tgattccact accaagatga ttctctcgaa ttttaaagct tgaagatgta ttgctatttt
    63241 tgctaactgg cgtatttgca actatttttc ccttctattc ttccttcatt gattcccctc
    63301 taaaattact atccataaaa aattgcataa atgacaatag tatttatatt agtcatactg
    63361 ctttttaaca cagcaaattc cagaaaaaca ttcgttacat atttgtgaat ttttccaaaa
    63421 aataacattt ttataaaacg acgaaaaata aatcactacc agtcaacttc tataatatta
    63481 ccaaata
//
LOCUS       DACGEU010000006        61969 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.006, whole genome shotgun sequence.
ACCESSION   DACGEU010000006 DACGEU010000000
VERSION     DACGEU010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 61969)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61969)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61969
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.006"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            303..1139
                     /locus_tag="IXR40_000349"
     CDS             303..1139
                     /locus_tag="IXR40_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HAQ4360225.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQVIVLVVLLVNCYNAFVILQTLGESRLTQVKITETYC
                     SK"
     gene            1203..1634
                     /locus_tag="IXR40_000350"
     CDS             1203..1634
                     /locus_tag="IXR40_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4360226.1"
                     /translation="MLREMRLGDAEALREINAEQLGYDVPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKHAEKRGIGKALMTGVEEA
                     KRRGISAIRLNSAEYRVEAHRFYERIGYHSDKMQKRFLKIL"
     gene            complement(1696..3018)
                     /locus_tag="IXR40_000351"
     CDS             complement(1696..3018)
                     /locus_tag="IXR40_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HAQ4360227.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFLDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRNVKPSIPQLGVGLMVSL
                     TFFILGQICNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(3172..4812)
                     /locus_tag="IXR40_000352"
     CDS             complement(3172..4812)
                     /locus_tag="IXR40_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
                     /protein_id="HAQ4360228.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAAFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAATILEKYEDKITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQTILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     KGLTPGQIPFARKRSEFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQKLNREEITDIKEAVESAKWVPEYKSLED"
     gene            5145..5615
                     /locus_tag="IXR40_000353"
     CDS             5145..5615
                     /locus_tag="IXR40_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HAQ4360229.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLGANKAIISELTV
                     GGLVDSLALAEGFIGEDIYEMFSEIRQLKKGENCIEVHHESPNVRFKRGDNEMIFNNH
                     VSDHTELYGIVNQILTELFGLGPYAFKEENGNPKLNEEWQETIEIQRNNPHLFQ"
     gene            5837..6940
                     /locus_tag="IXR40_000354"
     CDS             5837..6940
                     /locus_tag="IXR40_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HAQ4360230.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHQLIIPHVLKDVELPDTTTHFDKETLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDDGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
     gene            7224..7904
                     /locus_tag="IXR40_000355"
     CDS             7224..7904
                     /locus_tag="IXR40_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HAQ4360231.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGPLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            7994..9028
                     /locus_tag="IXR40_000356"
     CDS             7994..9028
                     /locus_tag="IXR40_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HAQ4360232.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTVPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNAFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            9042..9377
                     /locus_tag="IXR40_000357"
     CDS             9042..9377
                     /locus_tag="IXR40_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360233.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPIPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEQKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            9361..11841
                     /locus_tag="IXR40_000358"
     CDS             9361..11841
                     /locus_tag="IXR40_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360234.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLTDIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISPSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSLQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYESKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWKLTAGPTS"
     gene            11897..13456
                     /locus_tag="IXR40_000359"
     CDS             11897..13456
                     /locus_tag="IXR40_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4360235.1"
                     /translation="MRRKLLLLKSEMLEGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     VSVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQIRYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFAITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            13453..14817
                     /locus_tag="IXR40_000360"
     CDS             13453..14817
                     /locus_tag="IXR40_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAQ4360236.1"
                     /translation="MKIVIIGASHAGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQTIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEYTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            14988..16058
                     /locus_tag="IXR40_000361"
     CDS             14988..16058
                     /locus_tag="IXR40_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4360237.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAIGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            16073..16741
                     /locus_tag="IXR40_000362"
     CDS             16073..16741
                     /locus_tag="IXR40_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4360238.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEANELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            16761..17339
                     /locus_tag="IXR40_000363"
     CDS             16761..17339
                     /locus_tag="IXR40_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAQ4360239.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            17740..18651
                     /locus_tag="IXR40_000364"
     CDS             17740..18651
                     /locus_tag="IXR40_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAQ4360240.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(18739..19656)
                     /locus_tag="IXR40_000365"
     CDS             complement(18739..19656)
                     /locus_tag="IXR40_000365"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HAQ4360241.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELHKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            19858..20295
                     /gene="zapA"
                     /locus_tag="IXR40_000366"
     CDS             19858..20295
                     /gene="zapA"
                     /locus_tag="IXR40_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HAQ4360242.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            20354..20902
                     /locus_tag="IXR40_000367"
     CDS             20354..20902
                     /locus_tag="IXR40_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HAQ4360243.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            21017..23377
                     /locus_tag="IXR40_000368"
     CDS             21017..23377
                     /locus_tag="IXR40_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HAQ4360244.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEEQTIT
                     NWLQETEDGLKVQRLRGGIPIPKLENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLYDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNAYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            23464..23778
                     /gene="trxA"
                     /locus_tag="IXR40_000369"
     CDS             23464..23778
                     /gene="trxA"
                     /locus_tag="IXR40_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HAQ4360245.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            23960..25738
                     /gene="uvrC"
                     /locus_tag="IXR40_000370"
     CDS             23960..25738
                     /gene="uvrC"
                     /locus_tag="IXR40_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HAQ4360246.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKNFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELASKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMAKNDKHKTNELLFGTDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            25883..26782
                     /locus_tag="IXR40_000371"
     CDS             25883..26782
                     /locus_tag="IXR40_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4360247.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            26775..28037
                     /locus_tag="IXR40_000372"
     CDS             26775..28037
                     /locus_tag="IXR40_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4360248.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPVRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            28198..30096
                     /locus_tag="IXR40_000373"
     CDS             28198..30096
                     /locus_tag="IXR40_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HAQ4360249.1"
                     /translation="MDRYLDLLSEKFPSTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETDISQFTIFTAYPEYALTTDWYKEQDKS
                     QLIHHLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFAP
                     KNSKNLSEREQEELEKIHQALSILQFKSEHQLLDRRPEFKMDDRKLLEKIDYEASTID
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTAKEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDTKEEGSAIINGHTPVKVKKGESPIKANGKVFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRDTTKGMELQQQITQLKR
                     LLDYRKDD"
     gene            complement(30426..31145)
                     /locus_tag="IXR40_000374"
     CDS             complement(30426..31145)
                     /locus_tag="IXR40_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HAQ4360250.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIGQIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFTTHEVKIVSD
                     SLLSNLLPDPYFVNSYHHQAVKDLSPLLKAIAFSNDGLIEAVQSKDDMHKILGVQWHP
                     ELTHRVHPSEQRLFDFFVNEF"
     gene            31482..31814
                     /locus_tag="IXR40_000375"
     CDS             31482..31814
                     /locus_tag="IXR40_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360251.1"
                     /translation="MKQVLEALEQIRKAEEENEKRAQTLRQQLKIYATEKEQELETIQ
                     TNYRQQLKQLVEEKEQFEIQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            31801..33804
                     /locus_tag="IXR40_000376"
     CDS             31801..33804
                     /locus_tag="IXR40_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HAQ4360252.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFINKLKEVLDLKEKWEQLTEERDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAVIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKIKERFIHATYLIVLQGWVDAEEKQNLLHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLVEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLLVLPRGMKRFVKFFEILSIPSIIWGLIYSSFFGQSLPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALVGAMLIKNTAFVYLGAGLSIIAALCILIVPIIQTPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            33823..34293
                     /locus_tag="IXR40_000377"
     CDS             33823..34293
                     /locus_tag="IXR40_000377"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HAQ4360253.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            34314..34898
                     /locus_tag="IXR40_000378"
     CDS             34314..34898
                     /locus_tag="IXR40_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HAQ4360254.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQVETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAVTEMENWDESEQ
                     IQFIKNALYSLPLTGKVAFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            34913..35899
                     /locus_tag="IXR40_000379"
     CDS             34913..35899
                     /locus_tag="IXR40_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HAQ4360255.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNIDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFESETIRKRVRQVYDA"
     gene            35889..36200
                     /locus_tag="IXR40_000380"
     CDS             35889..36200
                     /locus_tag="IXR40_000380"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HAQ4360256.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            36222..38003
                     /locus_tag="IXR40_000381"
     CDS             36222..38003
                     /locus_tag="IXR40_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HAQ4360257.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            37996..39372
                     /locus_tag="IXR40_000382"
     CDS             37996..39372
                     /locus_tag="IXR40_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HAQ4360258.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            39379..40014
                     /locus_tag="IXR40_000383"
     CDS             39379..40014
                     /locus_tag="IXR40_000383"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HAQ4360259.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            40044..41399
                     /locus_tag="IXR40_000384"
     CDS             40044..41399
                     /locus_tag="IXR40_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HAQ4360260.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(41591..42985)
                     /locus_tag="IXR40_000385"
     CDS             complement(41591..42985)
                     /locus_tag="IXR40_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HAQ4360261.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRTQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            43077..44048
                     /locus_tag="IXR40_000386"
     CDS             43077..44048
                     /locus_tag="IXR40_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HAQ4360262.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            44045..44827
                     /locus_tag="IXR40_000387"
     CDS             44045..44827
                     /locus_tag="IXR40_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HAQ4360263.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(44996..45367)
                     /locus_tag="IXR40_000388"
     CDS             complement(44996..45367)
                     /locus_tag="IXR40_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HAQ4360264.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            45501..45944
                     /locus_tag="IXR40_000389"
     CDS             45501..45944
                     /locus_tag="IXR40_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HAQ4360265.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(45987..46796)
                     /gene="yidA"
                     /locus_tag="IXR40_000390"
     CDS             complement(45987..46796)
                     /gene="yidA"
                     /locus_tag="IXR40_000390"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HAQ4360266.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(46815..48182)
                     /locus_tag="IXR40_000391"
     CDS             complement(46815..48182)
                     /locus_tag="IXR40_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAQ4360267.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(48166..48996)
                     /locus_tag="IXR40_000392"
     CDS             complement(48166..48996)
                     /locus_tag="IXR40_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HAQ4360268.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLKDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            49159..49596
                     /locus_tag="IXR40_000393"
     CDS             49159..49596
                     /locus_tag="IXR40_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HAQ4360269.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTAGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            49672..50292
                     /locus_tag="IXR40_000394"
     CDS             49672..50292
                     /locus_tag="IXR40_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HAQ4360270.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            50481..50987
                     /locus_tag="IXR40_000395"
     CDS             50481..50987
                     /locus_tag="IXR40_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HAQ4360271.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            51004..51903
                     /locus_tag="IXR40_000396"
     CDS             51004..51903
                     /locus_tag="IXR40_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 and DUF4163 domain-containing protein"
                     /protein_id="HAQ4360272.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            51990..52874
                     /locus_tag="IXR40_000397"
     CDS             51990..52874
                     /locus_tag="IXR40_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HAQ4360273.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNHTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
     gene            complement(53066..53137)
                     /locus_tag="IXR40_000398"
     tRNA            complement(53066..53137)
                     /locus_tag="IXR40_000398"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(53102..53104),aa:Arg,seq:ccg)
     gene            53197..54531
                     /gene="rpoN"
                     /locus_tag="IXR40_000399"
     CDS             53197..54531
                     /gene="rpoN"
                     /locus_tag="IXR40_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HAQ4360274.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            54734..55771
                     /locus_tag="IXR40_000400"
     CDS             54734..55771
                     /locus_tag="IXR40_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SorC family transcriptional regulator"
                     /protein_id="HAQ4360275.1"
                     /translation="MLDEIKMIESVAPDIIEVLQERYKILRNIYWMQPIGRRSLSESM
                     GITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSLENFMDQLLGTHQTEQQLA
                     EYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEGENIIAVMGGTTMAVVAEQ
                     LSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKANGNHRALYVPEQLSLATYN
                     SLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEKELVMLKQANAVAESFGYF
                     FNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAIRAYMKNAPKQTWLITDEA
                     AANEILKGVTL"
     gene            55812..56813
                     /gene="gap"
                     /locus_tag="IXR40_000401"
     CDS             55812..56813
                     /gene="gap"
                     /locus_tag="IXR40_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HAQ4360276.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            56923..58113
                     /locus_tag="IXR40_000402"
     CDS             56923..58113
                     /locus_tag="IXR40_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HAQ4360277.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            58217..58972
                     /locus_tag="IXR40_000403"
     CDS             58217..58972
                     /locus_tag="IXR40_000403"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HAQ4360278.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            59088..60386
                     /gene="eno"
                     /locus_tag="IXR40_000404"
     CDS             59088..60386
                     /gene="eno"
                     /locus_tag="IXR40_000404"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HAQ4360279.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
     gene            60785..61924
                     /locus_tag="IXR40_000405"
     CDS             60785..61924
                     /locus_tag="IXR40_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HAQ4360280.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLAKHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHCIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
BASE COUNT        20470 a        10843 c        13064 g        17592 t
ORIGIN      
        1 tgaaattgtt ccttgtgact cggagctgaa cggcaggctc acgacctctt tcttaaacgg
       61 tgttcaaaag cttgcatctg cggtaataag ttcaaccaaa cgaaaattat gaggagctat
      121 ttttgtttgg ctgttcttat tacttgatgc aggacagctt tttcacaacc tcttttcgtt
      181 tagcactaaa tttccttaaa aagtagaaaa gctttcgaag cctcgtttgt ttcttttact
      241 gtataataaa agaaaagagt aacaatcgct aaaagatata aacaagagaa aggaaataca
      301 agatgattgg tctgatttat tttgtggtga tcgttctggc gaacacagtt ggcgctattt
      361 ccgggatggg tggaggcgtg ttgatcaaac cgattcttga tcttatcggc gcccattctg
      421 ttgcagggat ttctttttac tcaacagttg cggtattcac gatgtccatt gtttcgactg
      481 tgcgacaagt atcaagcggg aaatcactga attggcagat tgtcggttgg gtatctagtg
      541 gagctgttgt tggaggagta gtcggcaaca ttgtattcga agttttttta cagttatttg
      601 aaaacgagaa gcatgtgcag ctgatccaaa tttttttgac ggtattgacc ttggtttttg
      661 cgttcttcta caccaagcat catcagccaa aatttcattt gacgtcatgg acttggtacc
      721 ttatatgtgg gggggttctg ggctttttag ctagtttttt aggtattggt ggtggaccag
      781 tcaatgtttc tttgttgatg ctgatgtttg cattgccaat aaaagaagca acactatatt
      841 ctctatctac gattttcttt tctcaactgg caaaattggt aacgattgct ttaacaagta
      901 gctttatgcg ctttgattta tctatgttgt tttatgttat ccccgctgct gttattggag
      961 gtttgtgggg agcaagattt agcagggttt tgtctccaaa aaaagtgacc tttatttttc
     1021 aagtaattgt cctcgtggtt cttttggtca attgttacaa tgcctttgtc atcttacaaa
     1081 cattaggaga atctagacta acgcaagtca aaatcactga aacatattgt tctaaatgaa
     1141 aaaaggagta tactgtgata aaaaaattca tttaaaaaaa taaaaattgg ctggtgattt
     1201 ggatgttgcg ggaaatgcgt ttaggagatg cagaagcact acgagaaatc aatgcggaac
     1261 aattaggata tgatgtacca ttaaccgtta cggtgagaca aatgaagaaa ctgttgaagg
     1321 agccagaaaa aaattttttc ttggtctatg aagatcctac ttctaaaaaa gcagctggct
     1381 atgtacaagc ggagtcctat gaatcgattt tcagcgatcc gatgttcaat attatggcac
     1441 ttgctgtgtc taaacatgct gaaaaaagag gaatcggaaa ggccttgatg actggcgtag
     1501 aagaagcgaa aagacgagga atatcagcaa taagacttaa ttctgcagaa tacagagtag
     1561 aagcacaccg attttatgaa cgcatcggtt atcattccga taaaatgcaa aaaagatttt
     1621 tgaaaatcct gtaaattttt atcaaaaaat acctggtcat caagccgata cttgatgatc
     1681 aggtattttt tttgactaag aaagtaattg catcaagaaa cctgagatga tcaaaacgat
     1741 ggcaccacca agccgattgc ccatttgagc aaaagcaata agttccatcc gattagctgc
     1801 agataagaca gctacatttc ctgtaccacc catcgagttg ttgcataagc cagcagtaat
     1861 agttgattcg attggatata aaccaaacaa acgaccgaca aatcctgaaa ctactgaaat
     1921 cgcgataaca cttgtcaaac ataagacaac aaattgccat gtcaaagcag aagccaatac
     1981 atttagattc aataacgcaa taccgatacc ggcaagaaca gctgctgtca agtttttgac
     2041 aatcaagttg ttgaacatga tagctgcatc ttcgtaatat tctggtaata ggtttgcgat
     2101 tttacagata acaacgataa tgatcatgaa tgcgtaagca tggactttag gaacaaaata
     2161 gttacagatt tgtcctaaga tgaagaaagt caatgatacc atcaaaccga cacctaattg
     2221 tggaatggaa ggttttacat ttctaggttt tccatcgcca aggtcgcctt tttccattaa
     2281 tttaccatta ccgttgaatt ttggcattga ttgtcccgca cgagcaacta acgctgcacc
     2341 aatgatagct aggacatttg tcattgctgt cgcaggaatc aggcgggaaa tgatagaaga
     2401 agcgtccgta cctaaaacat ttgcataaat cgttgataaa ggtacagctc cggctccaac
     2461 accaccagcc attgcgggca atgagatata taaaacggaa tttgcaaaac catttccgat
     2521 aagcatacct acgagtccta cggcaaaaaa ggagacgacc attgaaataa gtgcaacggg
     2581 aataaaacga acagaagctt tcatcaatag attacggttc ataccaagga tgctaccagt
     2641 aatcaaggca gcaatataaa agtctaaaaa gcccatattg ctgacaaagt tttctgtgga
     2701 ttttactaca tactcaggta agatcccaaa tgtagcaatc gcggcagagg caaagatcgc
     2761 aaaaacggag ccaccaccta aataactttt gacgataggg atttttgttc cgataaaatg
     2821 aaataaatta ccgaaaatga ccaaaacagc gattgggcca atcatattcg tcggtaattt
     2881 tcctaaagcc attgcaatga tcaggacaag gaccatgatc aaataaaggg gcaaacttac
     2941 gccggtaatt tttgttgacc aaaacccttc ttttttcttt tcctcaactg cagttgcggt
     3001 tgttgttttt tgtgccattt ttacagatcc tttcttattc tgtatcgtat gaaaaaagcc
     3061 aaagagaagc ggcaaaagag cagtagttgg ctggctgctg ttttgccgca gtcgcttttt
     3121 tctttttaga cgtcatacaa agtttctgta tgttctttta ctataacaat cttaatcttc
     3181 taaagattta tattcaggaa cccatttagc agattcaaca gcttctttga tatccgtgat
     3241 ttcttcacga ttcaattttt gtgcaacaac tgattttgcg acagtttcag caatcgtttg
     3301 agagaattca gtgatttttg ctactggagg caagatagct gctcctggtt ttgttacatc
     3361 aacgattccg cctaatgctc gactagcttg agaaatgatt tcagcattta ctcgtgtagc
     3421 tgttgaagca atcaaaccaa gccctaaacc tgggtacatc aacgcattat ttgcttgacc
     3481 gatttggtaa gttacaccgt tatattccac atcagcagca gggatacctg ttccaactaa
     3541 agcttttccg tccgtccatt caatcaaatc ttttgctttt gcttctgcca attttgttgg
     3601 attagacaaa ggcatgatga ttggacgtgg ggtatgagcc gccatttctt tcacgatttc
     3661 ttcagtgaat gctccaggtt gggtagaagt accgatcatg atcgttggat ggattgcttt
     3721 tacaactgct tctaagtttg tcaattcatc agcattagtg aattctgagc gtttacgagc
     3781 gaatgggatt tgaccaggag tcaatccttt tgtatcttca aacaataaac cctgtttatc
     3841 tacttgatag aaatgttggc gtgcttcttc ttcaggtaca ccttgacgga tcatttcatc
     3901 taaaaggatg tttgcgatac ctacaccagc agtaccagca ccaaatgtca agatcgtttg
     3961 atctttcaat tgctcacctg atatattcaa tccacctaat acaccagcta gtacaacgat
     4021 tcctgtgcct tggatatcat cattgaaagt agtgatttta tcttcgtatt tttctaagat
     4081 cgttgcagca tttcctcgtc caaaatcttc ccaatgtaat aacaattctg ggaataattc
     4141 agtagctgat tgaacgaatt gatcaatgaa ttcgtagtaa gtttcgcctt ctacacgagc
     4201 atgacgattc cctaagtata atggattatt caataattct tcgttattag taccagcgtc
     4261 gattgataca ggcaagactt gtgcaggatt gataccagcc gcagcagtgt agaccatcaa
     4321 tttaccgata gcgatgtcaa caccgttcac accccagtca cccataccta agattccttc
     4381 tgcatctgtc acaacgatca aacgaatgtc gcgtccatct gctgcgtttt tcaaacttgc
     4441 tttgatattt tctggttcgt cgattgaaag aaatgcagca tcttgtggtt tcaagaaaat
     4501 ttcgttgtat tgttcgattg aatccgcaac gacaggatca taaacgacag gcatgaattc
     4561 aactaaatgt tcgcccatca atttataaaa caatgtccgg ttcgtattga atagattcat
     4621 taagaagata cgtttttcca aatcggtctg tttgcttaag tattgaccgt aagcttggac
     4681 agattgttgt tccaatgttt ggacagtact tggaagcata ccagtgattc cgtattttgc
     4741 ccgttcttct tttgtaaaag ctgttccttt atttagaaaa ggattattta ataagtttag
     4801 ccctgtaagc atgaatgatt cctcctaagt tttaatacaa acgaagtata ggagtcagat
     4861 gaggatatag tcaaaaagag caggtataat aaattttatt tatatgagta atagagtcaa
     4921 aagaaatcaa aatagcggta tttgttcttt ttatatcaac aatccttgct tgattactat
     4981 gcgtatctct tatatgctaa agaaagaaaa gtagaagaat aaaggatatg ttagatagat
     5041 aaatagaatc tctgaagaat aaatcacgtg atcgtgacga taaaatacac ttacgtcagg
     5101 tgataaaaaa tacataagta gaaaactaag aggaggaaca gaaaatgaaa gaagttcaat
     5161 tgatcagaaa aagcgaacta tcagaaggtg gttgcaatgc atgcggcgta gtagaagcaa
     5221 caagctatac attaaagctt ggtgccaaca aagcgataat ctctgagttg acagtaggcg
     5281 gtcttgtgga cagtctggcg cttgctgaag gttttattgg agaagatatt tatgagatgt
     5341 tttcagaaat ccgtcagtta aaaaaagggg aaaactgcat agaggttcat catgagagcc
     5401 cgaatgtgag attcaaacgt ggtgataatg agatgatctt caataatcat gtgtccgatc
     5461 acaccgagct atatggaatc gtgaatcaaa tactaactga gctttttgga ttgggacctt
     5521 atgcgttcaa ggaagaaaac ggtaatccaa aattaaacga agaatggcaa gaaacgattg
     5581 aaatacaaag aaacaacccg cacttatttc aataggcatc cacagtattt cgtaaaaggg
     5641 actttgacac gacttttgtc aaagtcccat cgttttttat ctatttgtgt tctaaacatt
     5701 tctttcagag tagtaacaac tggaatgact gaaatgtaaa cagattattt gcctgtatca
     5761 atacggaaga gtaatataaa gtgtgtaaac gctatcatat tattcattca attttttata
     5821 gagggaaggc attgaaatgg aaaaaacgta tcaagcaggt acaaatgaag gaatagtgga
     5881 ttttatcaat atggaagatt tagaaatagc cgcttcacaa gtgattccag ctggtggtta
     5941 tggttacatc agcagtggtg ctggcgactt atttacttat caagaaaatg aacgggcatt
     6001 caatcatcag ctgattattc ctcatgtatt aaaagatgta gaattacccg atacaactac
     6061 acattttgac aaagaaacgc tgactgcacc aatcatcatg gcaccagttg ctgctcatgg
     6121 cttagctcat gtgaaggcgg agaaagcttc tgcaaaaggt gtagcagatt ttgggacgat
     6181 ctatacagca agttcttacg cttcttgtac attagaagag ataagagaag caggcgggga
     6241 gaaagcaccg caatggtttc aattttatat gagcaaagat gatgggatca atttggatat
     6301 tcttgaagtg gccaagcgta atggagcaaa agcaatcgta ttgacagcgg atgcaacagt
     6361 tggcggaaac cgtgaaacag accgcagaaa tgggtttacc ttcccactgc caatgccgat
     6421 cgttcaggct tatcaatcag gagtaggcca aacgatggat gctgtgtaca aatcttccaa
     6481 acagaagctt agtccaaaag atgtagaatt tattgctgct cattctgatt tgccagtcta
     6541 tgtgaaaggt gtccagtcag aagaagatgt ctatcgttca ttagaatctg gtgctggcgg
     6601 aatctgggta tctaatcatg gtggccgtca actagatggt ggtccagcag cgtttgattc
     6661 gttgcaatat gtggcagaag cagtagataa acgtgtacca atcgtgtttg acagcggtgt
     6721 acgacgcgga cagcatgttt tcaaagcaat cgcatcaggt gcagatcttg ttgctattgg
     6781 cagacccgtt atttatggat tgtctttagg aggaagtaca ggagtccatc aagtgtttga
     6841 tttctttaaa acagaattgg aaatggtcat gcaattagct ggaacacaaa cagtagaaga
     6901 tatcaaaaaa ataaaattgc gtgagaatcg ttttatttaa gaaacaaatg acgaaaaaaa
     6961 taggagtgcg gcagatgatg ccgtactcct atttttatag ttcaaggatg tcactaatag
     7021 aataatttga aacgaaaaaa taaaattgaa atattttttc atacttaata aaaaaggaag
     7081 aatattcatg taaacgattt tattgttttt ttctctttta tacaaaaagg gtcataattt
     7141 caagtaagcg gatgaattca tgaggatttt ttgcatactg tctctactat acttaggtca
     7201 ctaagaaaaa ggagtgattt attatgaaaa agaacatgat tgggacatta ttactttcaa
     7261 cacttcttct aggcggcttg gcaacaccag cttttgctga gggtcaagcg acttcaaaag
     7321 gagatattac ctttactgaa ccaacaaata ccgtggagcc tcttaaccct actgatcctt
     7381 caaaaccagt agagccagca gatccggaaa atccagcaac tggccagaca ggtcctttaa
     7441 cactggatgt agttcccgaa ttgccatttg gtacacacga gattgaaagc ggaacaaaaa
     7501 cgtatcaagt agacgcttca aaaaacgata caccttatct ccaagtatca gatcgtcgag
     7561 gtgtaggtgc agatggccaa gcacaagggt ggaacgtgac agtttcggtt tcagattttg
     7621 taaacggttc acaagttttg caaggcgctg aattagattt tggaacatcc actgttaaaa
     7681 gtacgtcaga taacgaatcc actggaccaa ctagtcaaac tgtaactggg ttgagtaaag
     7741 caagtgcagc gacaccaata tttacagcag caaaagatca aggtctggga acatggcttt
     7801 ctgtttatga tccagcaaat atcacactga aagtgccgaa agcagcagct ggaacattca
     7861 cggctgattt gacttggaac ctcgtggctg gcccagtagc atagagtatg aaataaattc
     7921 aacaaactgc ggtgaaaata ctataggtga aggatttttt accgcagttt ttgttgaaag
     7981 gatgtggtgg acaatgaatc aaagtaaacg actgtttgtt tcgttttttt ctattttaag
     8041 tctatttttc atttttccgt caatcagcca agcaaaggat tcagcaggag actttggaat
     8101 caaaccggta tttccagaga accaaataga taaagcaatc ggttattttg atttattagt
     8161 ggcaccggaa caaaatcaga cactagaagt aattatcagc aattcttcag atgaagaacg
     8221 aacatttgag gtctctgtca atccggcggt aacgagtgat ggtggaacga tcgattatag
     8281 tcaaaaaaac ccaacgttag atgagacatt gccgtttgat gtccgtgacg ttttgctcat
     8341 tgcgaaaaag gaaatcaatg tatcagcaca tgcagaaaca actgtaccta tagaagtgaa
     8401 aatcccagca aaaagcttta agggacgtgt attagcgggt attcatgttt cacctaaaga
     8461 agaagctgaa acagaaaatg ctacagaagg agcacaaatc aaaaatcgta ttgcttataa
     8521 tctcgcagtc gttttacaag aaagtcaaga gacgatagaa ccggatctga aacttttatc
     8581 aggagatttg gacgaggtca acgcaaagcc aactgttcag cttcgtttcc aaaatcctca
     8641 gcctaggatt atcagcaatt tgatatttac gagcaagatc ttttatgaaa atcagcttta
     8701 tattgaaaat acgtctaatg catttttagt tgcaccaaat tcgaattttc acttgaatct
     8761 tgatttagct ggtgataaag caaaagccgg cgattaccgc gcagaaatca tagcaaaatc
     8821 aggcgacagt aatgaatggc gatttacaca aaactttacg atcaaaaaag aaaaagcaca
     8881 aaaagtaaat gaaaattccg tttttgcagt acaagaacaa tctttcccat ggctttatgc
     8941 aggattggtt gctgcagttc tagtgttatg gttgattttg ctgtttttgt gggtccacaa
     9001 gaaaaagaaa aaaggagaaa caacatgatg aggtgatttc gttgaaaaca tcgatcttat
     9061 tgggagggat tattgcaagt ttgctgttct tcagctggca agagccagtc caagcagata
     9121 ccaaaagttc aggtacgatt acattttatg atctaagtcc aattccgcat ccaagtggtt
     9181 cagtcaatgg cgcatcaaaa cagcagacac agctaccgat ttataaagaa tctaatcaac
     9241 atggcgtatt cccggagacg aatgaacaaa agatccgttt tctttatttg atcattggta
     9301 tagaattatg gcttcttgcg tggttgttgt tatggagaag aaaggaaaag gaggatgaac
     9361 atgttgctac aaaataaatt ttcatttttt cgctccttct tttttacttc gctttttgtt
     9421 ttaagtatat ttatcttttc accttcggca gaagctgttg gagcaacgcc tcctgccatt
     9481 tcttatgatc catacacgta tgaaaatatc gtacctccaa atggtggacg tagtgcagtc
     9541 aatggcggga agcttgtcca actaactggg gctaaccaat tgcctaaatt gactgctact
     9601 tatttgaacg atggttcaaa tgatccttgg aaaggtggca cggtccgttt tcattgggaa
     9661 agccatgtga aactaacaaa tgtacttgat ttggtgaata tcactgcaca aggatttgca
     9721 tttgtggcga tcatcaattt gccggaacat gtatcaagca gtgatgtatt aaaagcaatt
     9781 gactggaaca acgcctactt gtatattgcc ggtgccccca tcaaggttac tagcggaagt
     9841 ttattatcag caggaagcca taccttgcgt tttgggatgg ggtcgtggga tacaaatact
     9901 ctattgacag atattattgc tattattacg cgaggcgaat tcaacgtgga cgatatcccg
     9961 cttcaatttg atgttacagc taatgtcgcg aagatgacag aaaacggaga taaatatgat
    10021 acgagtccaa acaaaatttt gaccaagggt aaattacaac cttctatgtc taaaaaggcc
    10081 gttttttctg ttgattttta tgattcgaat aatattatcc aagatcgtat gttcaattcg
    10141 attttagctc cagctgcagg tagattttat cctaaattaa ctggcggaaa cttgaatcca
    10201 ggagcatatg cattttctgc aagtgcagag ataaatacgt ggaatagtta catctcacca
    10261 agtgattcaa caggaaaata taatacattt gctgatacca cagaatacgt ggatggaaat
    10321 aaccagaacc ttccaggctc taccaatagt cggacattga cgatggggct gactgaagga
    10381 cgttttgatc agttgccatt tagtcgcttt gatcgcgtag tcaactattt tacaggaaaa
    10441 aacgttacac aaggagcaat actgactcat actccagcaa gcacaagtgg attgaatcag
    10501 acagccaata tcgtgtacag tgggaaagat gcgcaaggcg gattgctttc tcctgttgct
    10561 ttaaaggtat tggagcagta caagctagac ggaacggttt taccaacaaa cttaacagcc
    10621 gatagtcagt ggggaaagct cctttcttct gcatcgtacc aagtcacggc caattggtca
    10681 gcaactgaac taaaaaaggg ttcgatccat tacaggcttt attcgaaagg aacccaaaaa
    10741 ttagcgacag gatggacaga tcaacttttc caaacgatcc aatcaaataa cgggggtgta
    10801 aatacagcta cttctacact acctgcattg gcttcagggc aatattattt tgattatcgc
    10861 ttggtggacg atgtacttac taacatgtat ccgtcttttg cgtacaaatg gcagtctgaa
    10921 caagctggaa tcaccactct tcctcaaata acagtggcta attttccatc tgtgagtgca
    10981 gatagtcagc taaaaaacct tagcagacaa cctgagacag gagatcccct gtctgctcta
    11041 tcaggagata cgattcaaga aaatgtgaca ttcacgttaa caaaatctgg ggatgcgata
    11101 accgacaaaa aaatcacgat ctcacttcct gaaaatacta cttatatcaa tggttcctta
    11161 aaattaaatg gtacaactat cgcagatacc ggcattcaac aaggagtttc tgtcccagca
    11221 gatctattga gcaaaatagg agataccatt catcttactt acaactatca attaaatact
    11281 gtagatactt ctttacaatc cgtcagcata ctgacaaagg cagctgtact ttccagcaat
    11341 attacattag cagatggtgc taagcttcct aacccagttg tccaaacatc tgctaaaaca
    11401 attcttgtcc ccaaacaaga attaacatta gttaatgtac cagatgattt tacatttggt
    11461 aacgatctcc ccaaaccgtt gaagacaagt tattatgaat caaaaggcga tttttctttt
    11521 gatgtgcggg atactcggct tccaagcacg tctccttggc aactgacagg tacattgact
    11581 tctttattta agaatgatca aggtcaagaa ttaagcggaa caaaattata cttcaatcat
    11641 tctggatcaa agcaattgat tcagcaaggt caaaacacgt tgatttatga gagtgatgga
    11701 acagctaaag gagaggttct cgttgacttt cccgataccg atggtttact cttagaggta
    11761 aatagcagta cgaatgctca acctggcgca acgtatcaag gcatggtcac atggaaactg
    11821 acagctgggc caaccagcta agtgattaga atttgtatgg atctgtgata actgtcacag
    11881 atcctctttt tcaaggatga gaaggaaact tctgctgtta aaatcagaaa tgcttgaagg
    11941 agtggacttg gaacttttca gtttgcttga aaaaaatgaa caacggcaaa tcaaactttt
    12001 ccaactttta ttagaggaaa aaggagaggt ttccgttaat aacgtactta cccgcttatc
    12061 agttgatcgg gctaccttga aagaagatct gttttattta caagctaact tggaaaatat
    12121 caaacaattg gaaattgtta tccaagaagg gaatatttta ttaatcagac atggaaatat
    12181 agcagcagtc gatgtttatt atcattgtta cttgcgctat tctacaaaat atcagatact
    12241 tctttatctg ttggaaaatg gctcatttga tcggcagaaa cttgtcatgg aacttaatat
    12301 cagttcggct actttgtctc gcagagtgaa ggaattaaat gattctttaa atgagtttca
    12361 tctgaaaata aaaagcgggc ggctgaccgg tccagaaagt caaattcgtt atttttattt
    12421 ccaattattt tggtttggac gtccctatct tgaaaacaaa aaagaataca gtgatttatc
    12481 aggaaacact tttttagatc tgctgcaaaa agagtttagt tttgctatta cagaagaagg
    12541 acgattgaaa tttgaaatat ggctttccat tatgaagaag cgaatgcgct gtacgaaaaa
    12601 atccaaacca gattatagca atcttcctgt tggattgttt caaacgacac aatttttatt
    12661 ggacctccat acatttttga cccgttactt ctttcaatat gcctttcctt ggaatcaaaa
    12721 tgaaacgttg gttttttatc ttttcatgat cagtaacttt acattagata cacataactc
    12781 gcatgtccag gagtttttga taagcgaaaa atacaaagac gacgtagtag ctcaattgaa
    12841 tcgaacgttt aaacaatcga tagaagaata tttctctttt tatgtttttc cagaagagat
    12901 ttcgcaaaag attgcgttga cagtgatgca aaatcacgct cattttgcct attttagagg
    12961 atggatgaat atttttggcc aagaaggatt aaaacagcgg ttaactgaag tagaagataa
    13021 acaattcctg gttttatgtg aaagattggt cagacaaaca tttgctattg ttgattttac
    13081 tgaagtagac gaggaaaatg cccgctttga attatttgct cgctatgcat ctattttacg
    13141 gacgctgatc aagcagttag aattacgtct gcaaattgct tatgatcttc cttatgaaag
    13201 gctaatggcg gatatcgtga aagaaatcat ccaggaacaa ttgctgaata cgatcaaata
    13261 tgatttagtc gaatacgaga aagaaaagca gtatgatatc attttgacta gccaattgaa
    13321 agagtacccg tcacagaagt ccgctaaagt ttttgtattc actagcaacg aatataatta
    13381 tgatttcccc tatttgaacc aatttttaaa agaatgttat ttagaaaaat tgaatttaag
    13441 gatgaataaa acatgaaaat cgtgatcatt ggtgcttccc atgcaggcat cacagctgcc
    13501 ctaaatctaa gaaaacttca accgaaagca gaagttttac tgatcgatga agatcataaa
    13561 gatggactag gctatgtttc aaatggaatc aacctttatt taaaaggaaa gatacgtagt
    13621 ttagctgaag ttgcccataa catgcggact cttcaagaaa gtggggcaaa actgatcacc
    13681 gaatggagag taactgaact tgatccagac aaacatcagc tcatcctcgc atccaaagaa
    13741 ggaaaaaacg agaccataac ctatgataaa ttaatcgtag cgacaggttc ctctcctgtc
    13801 accttgtata aacaaattga agctgaaaat gtctacacct ataaaaatct agtgcaatct
    13861 aagcaagtac ttgccgcttt aaaagaagca aaagaagtag tgatcttcgg tgctggttac
    13921 attggattgg aattagcaga tgctttgaga aataaaggat acattattca tctagttgat
    13981 tatatgccga atgttttatc aagatatttc gataaggata tgatcaacag ttttcaaaat
    14041 cagctgcaaa ctaagcaaat aaatttttat ccaaatgaat tcttgatcga ttggaaaaaa
    14101 tcagaagaga aagtagtatc cgtacaactt ctgtctcaaa caataaaggc agatatggtc
    14161 attttttctg cccaaactcg tcctaatacg acattgttaa aagaaaaagt ggctttgtat
    14221 gaggatgaga ctgtgatagt caatgaatat ctgcagacaa gtgatccgga catctatgcg
    14281 attggagata tcgtcccagt cagttttgac aaaaataaac ggcatctctt tttaccttta
    14341 gttactcgag ctgtacatat ggcaagagca gtagcgctaa ctttgagtgg tcagccaacc
    14401 gcttacgacc tcagacaaaa gataacagca gcagtcatta tagactactt tttaggaact
    14461 gtagggctga cagaagatga agcgccattc ttggaacaaa ataccggttc gtgttcagga
    14521 gaatttgatc tatttccaca atacgacgaa gaaaacaaaa cagtaaatgc aaagctgatc
    14581 taccatccgg atacattaga aataattggc ggacagctga taagccaaga attcttatta
    14641 tcagatttga acctgcttgc ggatatcgtg aaacacaaaa ctacgattcc acagctagca
    14701 gttgaggatt ttggatttct gtctgaatac acctctcgtt ttcactacct caatgagtta
    14761 gcttttaaag tactagctaa gagagcaaat agcaatagag tagataaaag actgtgagaa
    14821 atatcacggt cttttattgt gtggggatat aataaatatt aatcaatcga gaataaaaaa
    14881 ttcatataat gaaatagcgg aagaattttt tgagcataat attcgccaaa aatttatcaa
    14941 gtgataaaat tgttgtataa aatgattatt tcaggaggag gagttaaatg tttttagcat
    15001 taaatgaaat tatgcattca aagttacgtt atgcgttagt tgcaggggtg atgtttttga
    15061 tcgcctacct ggtatttttt ttgactgggt tagcttatgg cttagctcaa gataatcgaa
    15121 cagcagtcga caagtgggag gcagattcga ttgtgctttc gaaagatgca aattcaaatc
    15181 tagggatgtc catgattact aagaagatag cagaagaagt cgaaggtggg aaagtggcgt
    15241 atcttgccca aacacctgga gtcgtgacta gtaaagacag tacagaagaa ggaaaaatca
    15301 atgttagctt cttcggtatc gataaaaatc aattcatcat gcccaatctt gttgaaggaa
    15361 aagcttttga taacgatgat gaggcagtag gcgatattag tttgaaagaa gaatatggtc
    15421 tagccatagg agatacagtt aagttatctg gtagtgacaa gacgtttaaa ctaactggct
    15481 ttacggatca tgccaaattc aatgtctcac cagttctcta tacaaccatc aatgcttacc
    15541 aagaaatccg cttcgaaaaa gaagatacaa gtgaaaatgc acggattaac gcaatagttg
    15601 tcagaggtaa aatcagtaat ttacctgaag atttagaaca gatcaaaatt tctaaattca
    15661 tcaatgaatt acctggatat aatgcgcaag tattgacttt tggatttatg atcggatttt
    15721 tgatcgttat tgcggctatt gtgatcggga ttttcattta tgtactgacg atgcaaaaga
    15781 ttaatatctt tggtgtaatg aaagcacaag ggatcacagg aggatttatt gcgcgttctg
    15841 tagtggcaca aacattcatt ttatcatttg ttggtattct tcttggtcta ttaggaacag
    15901 tgggaacatc ccttgttcta cctgatgcgg ttccattcca aagcaattgg ctgttttttg
    15961 gcgtcattag cttgttgatg ttagtagtag ctgtgttagg cgcactattt tctgttcgga
    16021 caatcgtaaa aatcgatccg ttgaaggcaa ttggataaga aggaggaaga acatgaaagc
    16081 aatagaattt aaagaagtag aaaaaagttt ccaagatggc gaccaagtag ttaaagcatt
    16141 gaaagaaaca accatgagta tcgataaagg ggaatttgtt gcaatcatcg gtccttctgg
    16201 ttcaggtaaa agtacttttt tgactttggc aggcggattg cagacgccta gcagtggctc
    16261 tgtatttatc aatgatcaag aattcagtaa tcaaaaagaa agcgaacgcg ttaaactacg
    16321 ttttaaagaa attggcttta ttttgcaagc ttccaatctg gttccttttc tgacagtaaa
    16381 aaagcagtta ttattagtag ataagattaa acatgaacat cgtcaaaaag aagcaaacga
    16441 attatttgag cagcttggcg tggataagtt gatcaacaag tatccagaag aactatctgg
    16501 tggagaacgg caaagggtcg caatcgctcg tgcattgtac aatgatccgt ccattattct
    16561 agcagatgaa ccaactgcta gtttggattc agaaaaggca cgagaagtag tcgatatctt
    16621 ggcaaaagaa tcaaaagaca aaaataaagc aacgatcatg gttactcacg atacacggct
    16681 gattgacaaa tgcgatagaa tatttatgat ggaagatggt gtattgaaag aaaaagaata
    16741 accaaaaagc aggtggaaaa atggtccatc gatacaacaa agatacacag caaaaaattt
    16801 tgaaagaagc gactgacttg tttatgtcca agggatatct cggcacttca acaagagaaa
    16861 tcgcacaaaa agttgggatc acccagccca atctctatca ttatttcggt gataaagaaa
    16921 aactatatac ggcagtttta gaaaaccact taaaagatgt tggaaaagct ttgagagaaa
    16981 tcgttcaaac aagcgaaacg ggatttcaag taaccttgac aaaaatggcg cagtttttga
    17041 ttgagacaca tctggtcgat ttgtttctga tgcttcacga tcttgaaagc aatctttcaa
    17101 aggaaacaag agatcatctt ttctttctat ggaagaaaaa ttatcgtgaa ccttttgaag
    17161 aaatcttttc agcaaaccaa tctgtgctaa gaaatgggat ttcaaaagaa atcgcagcaa
    17221 ggcatttttt cttagtgtta gcaccttaca tcactcggtc gaaaagacct gtggaagaac
    17281 cgctaaatgt ggcgcaattg atcgatttat atttgaatgg tgtattagga gaagcgtaaa
    17341 gctgttatat agggagaaaa tagttaggtg aagaagcaag atatgacgaa gatcgttata
    17401 tcttgcttct ttatataggt agtttttcat aaagacaaat ttgttattct ctcatgatta
    17461 tcagggtata tttttattta ttatgtcggt gttccaggaa gtgttttaat ttaataacga
    17521 agaaattaat tgtttgtaga atgaaggaaa ctatttattg ggtagatgaa tcaccacgaa
    17581 tagtcaaaag gagatttcag gatatgccaa aaatgaaaaa aatcatttta gcagtaatgt
    17641 tattttctac ggttatatct tttacagccc cttttttgct tacttaagct gattttaagt
    17701 tttggccctt agtctggatc tacgaggtga gagtcaagaa tgaaaaaaat aattggagct
    17761 tttgtatttg caatcattat cattattatc tgttttcaaa tagatgtttt tggtcaaaaa
    17821 aagatagttg gacaaacggt cagcagtacg aacagtacgg ttacaaagac aaaggaatca
    17881 tttgatgata cagaacaaga gacattaatc aaaatcggaa aaaatgaccg tacactatat
    17941 acagatgact cgctaactac cccacttgca actataaacg gcggagagct ggcggagttt
    18001 ctttctgaaa caaaaaatgc ttatcagatc aagacaaatg atggctatac tggatattta
    18061 gccctcgaag atggaaccaa agtcacaaag aatatacaaa caaaaccgga agagctatct
    18121 gatgcagtga ttgtattaga tcctgggcat ggcggaaatg atactggggc attaagcaat
    18181 gatgaacaaa cagaagaaaa agatataaca ttaagtacag ccataaaagt aaaaaaggcg
    18241 ctagaggatg ctggagcaac ggtttatttg acccatacta cagatgaatt agtacagctt
    18301 ggagatatat gcgactacag tgaagaaaaa aaggcagatg tctttatcag tttacacgca
    18361 gactctacgg aatatgcgaa tgaagcaact ggaatcacga catattatta ctatggacaa
    18421 gaggaaacat tagcacagac aattgctgac tccttcactg atctgcctct ggattcaaga
    18481 ggaatctcca ctgggaacta tcaagttctt cgagaaaatc ttcaaccttc tattttaatc
    18541 gagatgggtt atatgaataa tgatagtgat ttaaaggaat tagtaacaga cagttatcag
    18601 cagcagattg ctgcaagttt gacacaagca ttgaccactt attttcagta ataaataagc
    18661 ccagccaaac aaaaatagct cctcatattt ttcgtttggc cgggcttatt atcgcagatg
    18721 caagcttttg aacaccgttt atttttttag tagcttcaaa gctttttctg tatttgcaaa
    18781 gtgaagtttg gcatattttt caagcatagg catgccgcct ttctccaata gttttgccgc
    18841 tacttggtca gatttcgttc cagctcctga tggaagggtg attccagctt cagctgatgc
    18901 tttgtgtaac tcttccaaaa agctggcacg actgatgata gaagcagcag caacagctaa
    18961 atgatattgt tctcctttag taacgaagta cagtttttct tgtaattgat ttttttctaa
    19021 acgcgcatat tttttaaaat ttgcttccgg cgtaaactga tcgatcaaaa tcgcttctgg
    19081 tttttctggc tcgatttttt ttagcagcaa atggatcgct tgattgtgca aagcgacttt
    19141 catccgaacg gcattgtatt ttggttggat ctcattgtat ttttctggag ataagacaag
    19201 cagtttatag gggatggttt tttttaagat gtcagcaagc tggatgattt ggctatcttt
    19261 taactctttt gaatctctaa caccaagttt acgtaattct gcaagctgat cacgtttcac
    19321 ataagcagca catactgtta gcggaccgaa atagctgcca tttccgacct catcactacc
    19381 taaaacggat aattgactga tattttttgg caaagaagag gctgtttttg ctggcttggc
    19441 ttgtttatcc tgtgcctccc cccatttatc agcttctatt gctgcattcg taccttgaaa
    19501 catcactttt ccggatgtat aagcggtaat ggtcgtcccg tctttttttg cagcaaagct
    19561 agtataagga atctgtttat ttaacaaata agagcgatag tatgctttca tttgactaag
    19621 ttggtcgttt gttgctttga taatgacgtt gctcataaaa ttctcctcgt ttttatacat
    19681 aaaactatac cgcaactcac gacttttcgt tttctaagag attgcgagac atagcatttt
    19741 tttaaagttt atcatataat agttaagtat gtgaaaaata tttgtggaga acggtgaaag
    19801 aaccaacttc atggtacact aaataaaact ttcatcaaat aggaggaaat gattcgtatg
    19861 gcgcacgaaa aaacacgcta caaagcggtg attgccaacc aaacatatac tattatcgga
    19921 cgggaaacca agcatcatat ggatatcgta acgaagctga tcaatgaaca gttagcagaa
    19981 ttgaaacaat tatcaccaca aatggataat gaacaagcag caatcttgat ggctgtcaat
    20041 gcgctttcgg atcaattgaa gaaacaagaa agaatcttgg agctggaaga agaaacagca
    20101 gaattaaaga aaaaaatgat caaatttaca gagcttgaaa atcgtgtgaa acgcattgaa
    20161 gcaatcgaga acgaagctcg ggaagtattg aaagaaaatg gtcaagcaga tcataccatt
    20221 aaaaatcatg tggaagcaca acagatttta aacgagaaac gaaaaggaca aattaaacaa
    20281 aaatcttcta attaagatcc ttttatcaaa ataagaaaaa tttaaaaaaa gttagaagag
    20341 aaaggaacgt agcatgctga gtttgctgat tttattttta ttgctaattg cgtttttttc
    20401 tggagcacgt cgcgggtttg ctttgcaaat catattcgcg attggatatg tattgtcatt
    20461 tattgctgcc cagcattttt acaaaccatt agcaagtcat ttggaattat acattccata
    20521 cccagctgtc acgccaacat caaagttagc attttttgat caggtatttg cctttcacct
    20581 agatgaagct ttttatgcag gaactgcttt tctgattatt ttgctaattg gctggctgct
    20641 tacccgattt gtgggggttt ttgtccatgg attgacgtat gtgccgatct tgagacaggt
    20701 agactggatt gcaggaggca tcctgtcact aatcatggct tacgttacta tatttttgat
    20761 tttgcagtta cttgcctttg ttccattaga tgtggtccaa aatcaattcg gcgagcatag
    20821 tttcgctcgc tttatcgttg agagaacgcc atttcttacc aacaagatgt atgagctttg
    20881 ggtaacgaat attttgaatt aaggaaaata gtgctggaaa atatttcgtt ttttgtacag
    20941 agtagattat ttaagaaggc tgcgtagcgt atgtccggca cagctctttt ttcatagtga
    21001 aagataaggt gataaaatga ataaccgaat ccttgaaaca ttggaatttg aaaaagtcaa
    21061 acagatggtc agacaatttg tagtgactgc acaaggaaaa gaagaactgg cagaattggt
    21121 accagtgagc gaggaacaaa cgatcacaaa ctggcttcaa gaaactgagg atggattgaa
    21181 agtgcaacgt ctgcgaggcg ggatccctat acctaaactt gaaaatatcc gtccccatat
    21241 gaaacggatt gagatcggag cagacttgaa tggagtggag cttgcacaag tttccagagt
    21301 attgtctacg acaagcgaat tgaatcgttt cattgatgat ctttatgaca gtgaaatcga
    21361 atttgcacgt ttgtatatgt gggcagatca gttagtcacg atccctgttt tgagccgccg
    21421 tttaaaggaa gcaatcgatg aagacggacg cgtgactgat gacgcttctc ctgagttaaa
    21481 gagcataaga cagaacattc ggcgaagtga acaagctgtt cgtgaacagt tagatgggat
    21541 cgtccgtggg aaaaatgcaa agtatttaag tgatgcgatc atcaccatgc gaaatgaccg
    21601 ctacgttatc ccagtcaaac aagaataccg cggtgtattt ggcggtgtag tccacgatca
    21661 aagtgcttca ggacagactt tatttattga accaaaacaa gtggtggatt tgaataatcg
    21721 tttgcgtcaa taccaaatcg ctgaacgaaa tgagattcaa cgtattttaa gtgaactttc
    21781 tgctgaactt gttccccatc gtcaagaaat catccacaat gcttatgtga ttggtaaaat
    21841 ggatctgatg aatgcaaaag cacgatttgg taaagaagta aaagctatcg tgccgggaat
    21901 cagtgaagac aatcatgtcg tcttgaaaca agcaagacat ccactgatcg atcaggaaaa
    21961 agtagtttct aatgacatca caatcggaaa agactatcaa gccatcgtca ttacaggacc
    22021 taacacaggt gggaaaacga tcacgttgaa gactttaggt ctgttacaac tgatggggca
    22081 agcaggatta ccgattcctg caggtgaaga aagtcaaatc ggtatttttg aggaagtatt
    22141 tgcggatata ggagacgaac agtcgattga gcaaagtcta tcgacctttt cttctcatat
    22201 gacgaacact gtagatattt tatcaaaagt caatgaaaaa agtctggtat tatttgacga
    22261 gctcggtgca ggaacagatc cgcaagaagg tgctgctcta gcaatcgcaa tcttagatga
    22321 tcttggtaaa aagtctgctt atgtgatggc aacaacgcat tatcctgaat tgaaagttta
    22381 tggatataat cgggcaaata cgattaatgc cagcatggag tttgatgtgg atacattaag
    22441 tccaacgtat cgtttgctga ttggcgttcc tggacgaagc aatgcgtttg aaatctctag
    22501 ccgattaggt cttgatacag aagttattga tgaagcgaag cagttgatga atgatgagag
    22561 ccaagattta aacgaaatga tcacagattt agagaatcgc cggaaaatgg cagagaccga
    22621 atatctggaa atgcgtcatt ttgtttctga ggcacaagaa cttcacgatg atttgaaaga
    22681 agcttacagc tatttctttg aagaacgtga aaaagaaatg gaaaaagcaa agaaaaaagc
    22741 aaatgaagtc gtgtcagagg cggaagaaaa agcagaaaaa atcattgctg atattcgtaa
    22801 aatgcaacag cagattgggc aaggaaatgt gaaagagcat cagttgatcg atgcaaagac
    22861 ccaattagca aatctacatc aagaagaaac tttgaagaaa aataaagtat tgaagaaggc
    22921 gaaagaacaa aaaacgttga aaccgggaga cgaagtgttg gttacgactt acggccaaag
    22981 agggacgctt ttacgtaaaa acgggaatca gtggcaagta gaaatcggta tattaaaaat
    23041 gaatgtgtcc gaagacgagc tgacgcctgt tgctcctcaa aaagagccga cacaacgagt
    23101 tatccatgct gtacgatctg aatctagtag tcacgtgccg aatcaattgg accttcgagg
    23161 aaaacgatac gaagaagcgc taagtgaggt agatcaatat ttggattctg ccattctagc
    23221 tggttatcct caagtgacta ttgtccacgg aaaaggaaca ggcgcacttc gcaagggaat
    23281 tactgattat cttaaaaacc atcggagcgt caaaagcttt gagtttgcac cggcaaacca
    23341 aggcggaaat ggtgcgacaa ttgttaaatt taagtaaagc ttactaaagg taagcagatg
    23401 gttcgctatc caagtataga aatgctatac tagtcataga ttttaaaaat ggaggtcttt
    23461 gatatgtcac aagtaattac agataagaca tttaatgaag aaacagataa aggacttgta
    23521 ttgattgatt tttgggcaac ttggtgtggt ccatgtcgta tgcaagcacc gattttggat
    23581 cagttggaac aagaatatga tgaagaagaa ttcagaattg ctaaaatgga tgtggatgaa
    23641 aatccagaaa ctcctcaaca attcggtatc atgagcattc caacattaat gttgaaaaaa
    23701 gatggtcaag tagtagaaaa agctgttggt gttcattcaa aagaacaact acgtcaaatg
    23761 atcgatcaat atttataaaa acttacagca aaaataagct gagggtggga ctgaatccag
    23821 ttccgtcctc ggtttttttg cggttgagtt aaggttattc aaattaatat tttttgagta
    23881 taattacgtt gtcaggctgg attgtttttt tgacagacat gctataataa ctttaattga
    23941 atatgaaggg gagtaccaga tgaacgaacg aatcaaaaac aaattagctt tacttcctga
    24001 tcagcccggc tgttacttga tgaaagataa aaatggaacg atcatttatg tcggcaaagc
    24061 caaaatatta aaaaatcgtg tccgctcata ttttactggt agccataata cgaaaacgga
    24121 acggcttgtt agtgaaatcg aagactttga atacatcgtt acagaatcga atatcgaagc
    24181 attgctctta gagatcaatc tgataaagaa aaatgatcct aaatacaaca ttatgttaaa
    24241 ggatgataaa acctatcctt tccttaagat aacgaatgaa aaatatcccc gtttggtgat
    24301 tactcgtaag gtactaaaag acaaagcact gtattttgga ccatatcccg atgtcggtgc
    24361 ggcgaatgag acaaagaaga tcctcgatcg attatttcct ctgagaaaat gcaaacctag
    24421 tcagacgaag gagccttgtc tttactatca tttgggacaa tgtctgtgtc cttattattt
    24481 cgacgtagat ccgaaagtct atacgaaaat cgttgatgaa gtgaaaaact ttttaaacgg
    24541 aggacacgaa aaaatcgagt cagagatcca tcagaaaatg gaaaaagctg ctgaaaacat
    24601 ggagtttgaa aaagctgcag aataccgaga ccagatccgt gccattgaga caatcatgac
    24661 tcgccaaaaa atgacaaata ctgatttact ggatcgagat gtatttggtt atgcgattga
    24721 taaaggatgg atgtgtgtcc aagtgttttt cgtaagacaa ggaaagctaa ttgaacgaga
    24781 tgtttcaatg tttcctttct ataacgaagc agaagaagat ttcttgactt acctcggtca
    24841 gttttatcag gaaaatgagc atttcattcc taaagaagtc ttgattcctg atacgatcga
    24901 caagcccagt gtagaagctt tgttagctac gaaagtgctg caaccaaaac gaggagaaaa
    24961 gaaaaaatta gttgaattgg cgagtaagaa tgcctcagtt gctttgaatg aacggtttga
    25021 tctgattgcc agaaaacagg aacggacgat cggagcagtt gaacgtttag gaaacgcgat
    25081 gaatatcccg accccaatac gtatcgagtc ttttgataac tctaatatca tggggacgaa
    25141 tcctgtggct gcgatggtcg tattcattga tggaaaaccg gcaagaaaag aatatcggaa
    25201 atataaaata aaaacagtca acggaccgga tgattatgca tcaatgagag aagtcatcta
    25261 tcgcagatat tcgcgagtga ttcgcgaagg gttgccttta cctgatttga tcttgatcga
    25321 tggaggaaaa ggacaagtag atgtggcaaa agatgtctta gaaaatcaat taggaatcga
    25381 tattcctatt gctggcatgg caaaaaacga taaacataaa acaaatgagt tgctattcgg
    25441 tacagatttg gctgtagtac cgcttgagcg aaattcacca gagtttttct tactccagcg
    25501 aatccaagat gaagtccatc gattcgcaat cactttccat cggcagctac gcagtaaaaa
    25561 cagttttgct tcccgattag atgaaattga agggttagga ccaaaacgaa aaaaaatgct
    25621 gcttaaagag ttcaaatcgt tgaaaaatat cacagcagcc acgacagaag aattacaaga
    25681 aatcggactg ccgaaaaatg tcgcacaaaa cgtatttgat aaattacatc aggaatgagg
    25741 aaagggcact ttacaaagaa agtaaagtgt cctatcattt tatgtacaac aaaaagagcg
    25801 tttacgtttt gttggtaaat aataaatcgc ttacgtctgg tgtctaagga tatatgtgat
    25861 ttcttgaaga aggagtgaag aaatgttaga agtcaaggat cttgttaaaa cttttgggaa
    25921 ctacacagct gtcgatcatg tctctttcca aatccccgat ggaaaaatca tggggctaat
    25981 tggccaaaac ggggctggga agacaacgac ttttcgtttg atcttggatt ttttgacaca
    26041 agaccaagga gaagtgttat ggaatggcca tcatcttggg gagaaagatt atgatgtcat
    26101 cggttatctt ccggaggaac ggggacttta tccgaaagta acgattcaag accaactgct
    26161 ttattttgca gaacttagag ggaaatcaag aaaagagatt gaaccaaaaa tcgacttttg
    26221 gatggaaaaa tttcaggtaa aagggaaaaa gacggataaa gtaaaatctt tgtctaaagg
    26281 aaatcagcaa aaagtccagc tgatcgccac gttaatccat gaacctaaat tgatcatttt
    26341 ggatgagcca ttcagcgggt tagatccggt aaatgctgaa ttgctaaaag atggaatatt
    26401 ggaattgaaa aaacatggtt catgtgtcat tttttctagc cacaatatgg ataatgtaga
    26461 aaaaatctgc gatcatttga tcatgttgcg aaacggaaaa atggttttga atggaaaagt
    26521 acatgagatt cgtgaatcat ttggccgtac gaagttattc ttggaatctg gtttaagcca
    26581 acaggaagta gaagaaatcg aaggcgtgaa aaaagtgatc cttcatgaag acaatacgtt
    26641 agagattacc ttagaagatc ctgaagctgg gaaagaaatc tttactcgtg cgactcagtt
    26701 cggctacatt cctatgttta accagcaacc gccaactttg gaagagattt tcaaattgaa
    26761 agcaggtgaa atcgatgcgt aagttttgga ttattaccaa agatgtctat ttaaaaaatg
    26821 ttaagtcgat ttctttcttg atcatgatat tagtcccttt tatcatgctg ggtatcattt
    26881 atgtagcagg aaactttgct caacaaaata gtgatgtcaa taaaatcggc gtattggctg
    26941 ataatgagca aatcagtcag caaatgagcc aagtcaaaac agatgatttt gagttcaaag
    27001 cagttgattc tgaagaaaaa gcacaaaaag agctttcgga agaaaaaatc gatgcgtatt
    27061 tagtagtctc aactgagaat gataagataa atgggatgct ttatagcgaa aattcattag
    27121 gacaaagtac acaactactg atacaacaac aactgactgg cttgcaatcg atgcttcgag
    27181 cgagtcaatt aggcatttca ccagaagaag tagctagctt gagccaacaa gcaagtttga
    27241 ctcgacaaaa agtcaatttt gattcaaaag gaaaaatgac agtcggagaa gataactcga
    27301 cagtccaata cgtcgtaagt tatgtagcaa cgattgtctt gttcattatt attttgacgt
    27361 atgcgcagat cattgcacaa gagatcgctt ctgaaaaagg cacgcggatc atggaagtga
    27421 tcctgtccag tacgactgca caaaagcatt tttacggaaa attaacaggt gttttacttg
    27481 ttgcattaac gcaaatggca ttatacggta ttatttttgg tataggatac agtcaattca
    27541 aagatatgga aatggtcaaa aatatattag acggtatctc attggataac ttgattggac
    27601 cattcttgtg gtattctctt ctattcatga tctttggcat tttgattttt tctgttttag
    27661 cagctttatg tggctctttg gtcaacaaag cagaagatac agcaaaagca attttgccag
    27721 tgacttatct atctctaggc ggatacatgc ttggattgat actaggagct tcagatccaa
    27781 acaatatcgt tattcggatc acttcgtata ttccattctt atcttcatat attatgccgg
    27841 ttcgcttagc aaatgagaca gtcggtatgg gtggagcatt gatttccttg ttggtacttg
    27901 tagccgtaac attcttattg atgatcttgt ctgcaaacat gtacaaatcg aatgtactcg
    27961 tttatagcga aggcggatta tggagttcat tgaaacaatc gatttcaatt atgaggaatg
    28021 aacgaaaaaa agcataaaac aatcctaaaa tacagaagga agctggacat ctattgttcc
    28081 cagcttcttt ttgtatagac ctattttatt tattttacta tattggatat atattcattg
    28141 aaaatagtgt ataacaactt tataatattg agtataccaa tttttggagg cgttttaatg
    28201 gaccgttatt tagatttact ttcagaaaaa ttcccctcaa cggaggatgt catcacggaa
    28261 atcatcaatc tcgaagcaat tttgcagctt ccaaaaggaa cagagttatt tttgagtgat
    28321 atacatggcg aatttcctgc ttttgatcat attctgcgta tcggttcagg aaatcttaaa
    28381 gaaaagatca aagacctttt ttctgaacaa atgacggaaa cggatatcag ccaattcact
    28441 atttttacgg cttatccaga atatgcatta acgactgatt ggtacaaaga acaagataaa
    28501 tcgcagctga tccatcattt gatcgatctt ttacggttta cgacagtcaa atatacccgg
    28561 tcaaaagttc gaaaaggatt gccgaaagaa tatagctata tcattgagga actcttgtat
    28621 atcgatgacc gtatcaatgg aaaaaaagac tatgtaaaaa aaatcattga acaacttgtt
    28681 ttgatgaagg aagaagaaaa atttttaacg aaacttgcac agacgatcca aaaatctgtc
    28741 atcgatcatt tgcatatcgt tggagatatt tttgaccgag gaactcaagc agccaaagtg
    28801 atggatcgaa tcatggattt ttcttctgta gatatccaat ggggaaatca tgatattttg
    28861 tggattggtg cgtattgcgg ctctgaggca tgtttactga cacttttacg gattgcagca
    28921 cgctataatt atttatttga attagagaaa gaatatgggt tgaatttacg tccattgttt
    28981 tcttttgctc atcaaactta tcagaagaat ccagtatttg cgcctaaaaa cagtaaaaat
    29041 ctatccgaaa gagagcaaga agaattagaa aaaatccatc aggcactttc tatccttcaa
    29101 ttcaaatcag aacatcagtt attggatcgt cgacctgaat ttaaaatgga cgatcgtaaa
    29161 ttgctggaaa aaatcgacta tgaagcatca acgattgatt tagaaggtca gctctatgag
    29221 ttgaaaggaa cttgttttca aacgatccag ccagatgatc caaaaaaatt cttggaagag
    29281 gaacaaaaag tgattgatag tttgatgtat tcattccagc actctttgag aatgcaaaaa
    29341 catatgacgt ttttgatcga aaaaggggga atgtatctca cgaacaatca gcatgtgctg
    29401 tttcatggct gtatacctgt agacgagaag ggacagctct tagcatttga attagaccaa
    29461 tcttatcgcg gaaaagaact gctgggcttt tttgaaaaac agataactga aagcgcaaaa
    29521 gatctgactg caaaagaaga tttagcaacc gatttgattt ggtatgcgtg gagtgggcca
    29581 ttttcgcctt tattcggcaa gagtaaaatg gcgacttttg aacgttattt tctcacagag
    29641 cctcatacgc acgtcgagaa aagcaatcct tattatcact tgcgagatga agagtggttc
    29701 agtgaaaaaa ttttagcaga attcgacaca aaagaagaag ggtcagcaat cattaatggg
    29761 cacacgccag taaaagtaaa aaaaggggag tcaccgatca aagcaaatgg aaaagtattt
    29821 gtcattgacg gaggtttatc caaagcttat caaaaaacga caggaattgc cggttattca
    29881 ctattatgca attcttatgg tttccaaatc gtgacacatt atccgttttt gcctattgaa
    29941 caacaatttg caaaaaaatc cgaccaaaca aatgtgaaaa aagtaatcga acagcaacta
    30001 ccacgcaaac tcaatcgtga tacaacaaaa ggtatggaac tgcagcagca gattacccag
    30061 ctcaaaaggc tgttggacta tcgaaaggac gattgagaag aattccagtg aacattgttc
    30121 catagactgg agactgagac aaaagtcgtg tcgcagtctc tttttccgga taaacggtgt
    30181 tcttctgcca actcctcggt cacaagtcac actattcaac aaacatgaaa agctgttttt
    30241 tgaaattgct ccttgtgact cagagttgaa cggcaggctc acgacctctt ggtataaacg
    30301 gtgttcaaaa gccagtttct cggtattaag ccaaatttat gcaaaaatgt gaaaagccat
    30361 tttcacaaaa tttttcttaa tactcgaaac taaacagctt tttcacaacc ccctcagaaa
    30421 gtctattaaa attcattcac aaagaaatcg aataagcgct gttcagatgg atgtacacgg
    30481 tgggtaagtt ccggatgcca ttgaacaccg aggattttat gcatatcatc tttgctttga
    30541 accgcttcaa tgagtccatc gttagaaaaa gcgatggctt ttaataaagg tgaaagatct
    30601 ttgactgcct gatgatggta agaattcaca aaatatggat cggggagaag gttgcttaac
    30661 aaactgtctg aaacaatctt gacttcgtga gtcgtaaatt gcggggcagt gggctgttgt
    30721 tcatgtttta ctgaccactt tggatataat gaaagatctt gataaagtgt accttccaaa
    30781 acgacattca atagttggag tccccggcag actgcaaaaa ttggttttct ttgtttcaat
    30841 gcttccaaga tcagtgcctg ttcaaattgg tctcgttgaa tatttgtttc cgttagcttt
    30901 ggatgaggat cttccatgta aagttgtgga ctgacatctt gaccacctgc aagaataagt
    30961 ttgtcgattt gtccaatcag ttgaggagct gaatctggag acatgactgg cagaataaga
    31021 ggcaatcctt gagcatctaa aactgcatcc acgaatcctt gcggtgtata gctcacttga
    31081 tttccttgga aagtatctgt tgctcgaatc agttgatttc cggcaatgcc gatgattggt
    31141 ttcatttgta ttccccctaa agtagactta ttgtaacaag gatttaaaaa aaattaaact
    31201 atgtaagact tgcccctata cttatctgtt cttgctgtgt tactatctgt aaagagaaat
    31261 ttcgtgtgaa attcatgacg atagttgaaa atattgctta atttgttata ataaaaagta
    31321 agcagaaata aaaaggttgg gcgtaagctt caaggatcta gttcttcaag gggtgagaag
    31381 gacattttat tgaaggggcc tgcctatact aagttatctt tagaggtaca tactttcaat
    31441 gaaaaaagaa agcatgtacc tcttttttaa atcgaaagga agtgaagcaa gtgttagaag
    31501 ctttggaaca aatccgaaaa gcagaagaag aaaatgaaaa gcgtgctcaa acactgcggc
    31561 agcagctgaa gatctatgca acagaaaaag agcaggaatt ggaaacgatc caaacaaact
    31621 atcgacaaca actaaaacag ttggtggaag aaaaagaaca atttgaaata caagaattag
    31681 aaaaagaaaa aatgaaattg aaagcagaag cagacaaggt gcaagcaact ttgaaagatc
    31741 aatatcaaaa gcatcagagt caagcgatcg gtgcgatcat tgaaagggtg aaagaaactt
    31801 atggccgtca ctaagatgga aaaagtgacc ctcatttcag ataaaagaaa tcaggagagg
    31861 attttacaag cagtacaagg aatccaaaac gttgaaatcc gggatctgta tcaaaataga
    31921 acaaacaacc agtgggtgga gaagtatttt ccagatacca cgattattga taaagaagca
    31981 aaattaagcg ctttaggtaa tcggttgaaa gacatccaag aagctatcca attcatacaa
    32041 caccacggcg atagccgtca aaagaaactc catttgaaac gtcaagaact ttccttacaa
    32101 gatttggaag ccaattattc cgaagaaaat ttcataaata aattgaaaga agtccttgat
    32161 ttaaaagaaa agtgggaaca actaactgaa gaacgtgatc gtttagaaga agaggaagaa
    32221 tggcttcttc attggcaaca gctggatatt gctccaagta tgtatgcaag taagacgacc
    32281 atttttgaga tggggactgt gagtgcagca aattttgaaa gtttcaagga agaactgagt
    32341 aagcttgatg acgtttatat ggaagaaata gattatacgc caaaacaagt ttatctttcg
    32401 tatgttgctt taaaaaaatc agttgctgtt atagaagaaa ttgctgggaa atacgggttc
    32461 aataaagaaa cgtatcctta tgaacaaaat cctaaagaaa aactgcaaga gaccaagcag
    32521 caattatcca ttgttcacga gcagcaaaag aagataacga cagcgttagg tcagtgcagt
    32581 ggctatatcc aagaatttga atgggtagaa gaagtcacac ttgccgttgc agaacgagaa
    32641 aaaataaaag aacggtttat ccatgcgact tatctgatcg ttttgcaagg ttgggtagat
    32701 gcagaagaaa aacagaattt gctgcatgtg ttaaacgaaa ccgtatcaga agaagatata
    32761 tacgtcagtt tcgaaacacc aaactcagaa gagattcagc aggaagtccc tactaaattg
    32821 aaaaaccatc cgcttgtcga accttttgaa ttgctgactg aaatgtacag tctgccaaaa
    32881 tatgaagaag tagatccaac accttggatg acaccatttt atcttgtctt cttcgggatg
    32941 atggtcgcag atgttggtta tggtttgctg atgctcattg ggacaatact agctcaaaaa
    33001 ctacttgttc taccacgcgg gatgaaacgt ttcgtaaaat tctttgagat tctctcgata
    33061 ccatcgatca tctggggatt gatctacagt tcatttttcg gacagtcatt accaaaagaa
    33121 ctgtttggca tccgcttgcc tttcccaatc ctatctacga cggatgacgt caatacgatt
    33181 ttgattttat ccgtgatttt cggtctgata cagattttgg ttggattatt tgtggcagca
    33241 aaggaaaata tcaggagaaa agattacttg agtgctgtca gtgatggatt tgcctggcaa
    33301 gggatcctaa ttgggatcgt tattgcgttg gttggtgcca tgttgataaa aaatacagca
    33361 tttgtttacc ttggcgctgg gctatcgatc attgctgcct tatgtatctt gatcgttccg
    33421 attatccaaa cgccgtctaa agtcaaaggt gctgccaaag gtgcgtataa tctttacgga
    33481 ctgaccggct atatcggtga tttagtcagt tatacacgtt tgatggcatt gggtatttca
    33541 ggcggaagta ttggagcggc attcaatatg ctagttgctt tcatgccgcc agctgctcga
    33601 ttcagtgtag ggatcctttt gatcatcgct ttacacgcac tgaatatgtt tttgacactg
    33661 ctaagtgcct atgtccatgg cgcacgattg cagtatgtcg aattttttgg gaagttttat
    33721 acaggaggcg gacgtgcctt tgatccgctg aaaacggcgg aaaaatacgt caacatcaat
    33781 cacaagaaaa aaaacaataa ataattggag gatttttata taatgatgga ttacttaatt
    33841 agtcaaaatg gtggaatggt atttgcggta ttagcgatgg caacagcgac gattttttca
    33901 gggatcggtt cagctaaagg tgttggaatg acaggtgagg cagcagcagc attgacaaca
    33961 agtcaacccg aaaaattcgg gcaggctctg attctgcaat tgcttccagg tacgcaaggt
    34021 ttgtatggat tcgttattgc ctttttgatt tttatcaact taggaaatga catgtcagtt
    34081 gtacaaggac tgaactttct aggtgcttct ctgccgattg cttttacagg cttgttttca
    34141 ggtattgccc aaggaaaagt cgcagcggca ggtattcaaa ttttagcgaa aaaacctgaa
    34201 catgctacaa aaggaatcat ttttgctgcg atggttgaaa catacgcgat tttaggtttc
    34261 gttatttcct tcctattagt gttgaatgcc taagcataaa ggaggaaaag cagatgaacg
    34321 ccattgaaaa aatcatctct cagatgaacg aagcagcaga gcaggaaaga gcggcgttag
    34381 aacaagaaga gcgaatgaag atcgatcaaa actttgaaca aaaacgtacg caagttgaaa
    34441 cagaacatca aaaacaaaaa gaaaaacaaa tcgaattact cgaaaaaaaa taccgtcagc
    34501 taaggaatcg ccagcaagta gaagtacgac aagaaaattt gaatgcgaag caggaatttt
    34561 taagacgatt gtttgcagat gcggtaactg aaatggaaaa ttgggatgaa tctgaacaaa
    34621 tccagtttat caaaaatgca ttgtattcat tacctttgac aggaaaagta gcattcattg
    34681 ctggagaaaa atcagcagcc tatctttctc agacgttgtt ggatgaatgg aacaatgaac
    34741 ttccctttat gatggtttta agtgatgaaa ctgttgctga tcaagcgggt tttctgataa
    34801 acgatcaagg agttcagtat aattttcttt tcagcagcct tgtacaagat atccaaggaa
    34861 cgatgagttt tgagattgcc aatcaattat tcgaataagg agggatcagt gtatggaata
    34921 ccacgaacta aatcccttga ttcgcggaag agagcttgaa cttttgtcca atgagacatt
    34981 tgaacggatg attcaaacaa attctgtcga agcacttggt gaaatattga aatccacgat
    35041 ttacagtcca tatatttatg acggatatga atatgacttc gaacagaatc ttttaaagga
    35101 gcagagccgt ctatttcgct ggttaaagga atcagcaccg gagcctgaaa tcgtttggat
    35161 ctatacgatg cgttatactt tccataatct gaaggttttg acaaaagctg agatgacaaa
    35221 tcaaaatctg gaccatttgt atatcgacga tggattttat tcattagaaa ccttgaagga
    35281 tgccattcat acgcaagttt caaatgaact tcctgaaagc attatggaca gtatacgaga
    35341 agtacgtgat tattttgaag agtctaccat tcttcaggga attgacgtga tttatgatcg
    35401 acagtttttg acagagcagc gacggcttgc cgataagcta ggatatcaag aattgctgac
    35461 agaagtcatt gcttttattg acttgaccaa tatcacaacg atggctcgag gaatattgca
    35521 gaaaagaaca tatgggttca tgacgacggt actttccagc tcgggaagta tcgaaaaaga
    35581 agtatttttg aactttgtag ataaagatat ggaagattac acgaattttc tattagagac
    35641 agattatgct gattttctgc gccctgtcat ccgtgaggga aatattgatc tcgtaaagct
    35701 tgaacagttg aaagatgatt atctaagttc attgtatcaa gaagcacaaa cccaggcttt
    35761 cggaccactg ccactactag cctttttgaa cgcaaaagag gtagaaagca aaaaccttcg
    35821 tttactggtt atcggcaaaa gaagccattt cgaatcagaa acaatcagaa agcgggtgag
    35881 acaagtctat gacgcataag atcggtgtag ttggcgacaa agattctgtt ttgccattca
    35941 aattgtttgg ctttgatgtt cgttatggta caaccaagca aaccgttcgt caggcaattg
    36001 aagaaatggc aaagaatgag tatggcgtga tttatgtcac agagcaatgt gcagcattga
    36061 gcccagaaac gatcgaacgt tacaaggaac aaatgatacc tgctatcgta ttgattccca
    36121 atcatcaagg atcattaggg atagggctgg aagaaattca aaaaaacgta gaaaaagcag
    36181 taggtcaaaa tatcttatag tatgaaaagg agatagaaat tttgcaaatt ggaaaaatca
    36241 taaaagtctc cggacctctt gtaatggctg agaacatgtc tgatgccagt atccaagaca
    36301 tgtgtctagt gggagatcta ggagttatcg gagaaattat cgagatgcgt ggcgatgtgg
    36361 cgtctattca agtatatgaa gagacttctg gaattggtcc aggcgaaccg gttcgctcta
    36421 ctggtgaagc tttatctgtt gaattaggac cagggatcat ttcacaaatg tttgacggaa
    36481 tccaacggcc attagatacc tttatggaaa tcacacaaag taatttctta gggcgcggag
    36541 ttcaattgcc cgcattggac catgagaaaa aatggtggtt cgaaccaaca gtagaagccg
    36601 gagaaacggt gagtgctgga gatgttatcg ggatcgtaga agaaacaaaa gttataaaac
    36661 ataaaatcat ggtgccaaat gggataaaag gaacgatcaa aacaatcgaa aaaggttcat
    36721 tcactattga tgaaacagta tgtgtcattg aaaccgaaaa tggtgacaaa aatttgacga
    36781 tgcttcaaaa atggccagta agacgtagtc ggccaatcaa agaaaaatta aacccggatg
    36841 cacccatgat cactggacag cgagtgattg atacattctt cccagtgaca aaaggaggag
    36901 cagcagctgt acctggtcct tttggtgcag ggaaaacagt cgttcagcat caaattgcaa
    36961 aatgggccga tgtggacatg gttgtctatg tgggatgtgg cgagcgtgga aatgagatga
    37021 cggatgtttt aaatgaattc cctgaattga ttgaccctaa tacaggagaa tcgttgatgg
    37081 aacgtacggt attgattgct aatacatcaa acatgccagt agcagctcga gaagcttcta
    37141 tctatacggg aatcacaatt gcggaatatt tccgtgacat gggttatgac gttgctatca
    37201 tggcagactc cacttcacga tgggcagaag cacttcgtga gatgagcgga cgtttggaag
    37261 aaatgcctgg tgatgaaggt tatccagctt atcttggttc acggcttgcg gaatactatg
    37321 aacgatctgg aagagtcatt gcattaggat cagaaggtcg cgaaggaagt ataaccgcaa
    37381 tcagtgctgt atccccgtct ggaggggata tttcggaacc agtcacacaa aatacattgc
    37441 gggtcgtaaa agtattctgg ggtcttgatt ccagtttagc ccaaaaaaga cattttcctt
    37501 cgatcgattg gatacaaagc tattctcttt attcaacaga agtagggaag tatatggatc
    37561 atatccttca agctgactgg gcatccatgg tcaccgaggg catgcgtatt ttgcaggaag
    37621 aacagcagct gaatgaaatc gtgcgtttgg tagggattga ttccctttca gataatgacc
    37681 gtctgacatt agaagtggca aaatccattc gtgaagatta tttgcagcaa aatgcttttg
    37741 atgatgtcga tacattcact tcaagagaga aacaattcaa aatgttgaag atgatcttga
    37801 cctttggtga agaaggacgc cgtgcgttgt cgttaggtgc ttatttaagt gagatcatgg
    37861 acggtaccgt atcgattcgt gaaaggatcg gacgaagcaa atatatcccg gaaacagaat
    37921 tagaaaaact agatcaaatt attggtgaaa tcaagcaaac gatgcaaacg atcgtttcag
    37981 aaggaggcat gagcaatgat taaagaatat cgtacgatcg gtgaagtcgt cggtccattg
    38041 atggcggttg aaaaagttgc tggtgtcaaa tatgaagaat taatcgaagt ccgtatgcaa
    38101 aatggcgaga ttcgtcgtgg acaagtattg gaagtccaag aagataaagc aatggtccaa
    38161 atattcgaag gaacaagtgg tatcaattta cgtgactctt ctgtacgatt tttaggccat
    38221 cctttagaac taggtgtatc ggaagacatg atcggtcgag tattcgatgg tttgggacga
    38281 ccgaaagata acggaccaga gatcctgcct gaaaagcatt tggatattaa cggagaagta
    38341 atcaatccag tagctcggga ttatccagat gagtttatcc aaacaggtat ctctgcaatc
    38401 gatcatttga atacattagt tcgtgggcaa aaattaccag tattttctgg ctctggtctt
    38461 cctcataaag aattagctgc tcagatcgcg cgacaagcaa cggtactcga ttcatcagat
    38521 gatttcgccg tagtctttgc tgctattgga atcacttttg aagaagctga atttttcatg
    38581 gaagattttc gtcaaacggg cgcaatcgac cgttctgtca tgtttatgaa tttagcaaac
    38641 gaccctgcaa tcgaacgtat cgctactcct cgtatggctt tgactgctgc agaatatctt
    38701 gcttatgaaa agggaatgca tgttttggtt atcatgacag acatgaccaa ctatgcagag
    38761 gcattgcgag agatttctgc agcacggcga gaagttccag gaagaagagg atatcctggg
    38821 tatctttaca cgaacttagc tactttattc gaacgagcag gaagaatccg cggactaaaa
    38881 ggatcggtta ctcaaattcc gattctaaca atgccagaag acgataaaac tcatccaatc
    38941 cctgacttga ctggttatat tacagaagga cagatcatct tgactagaga gctttacaag
    39001 agtgggattc agccaccaat tgatgtactc ccgtctcttt cgcggttaaa agataaggga
    39061 actggacccg gaaagacaag agaagaccat gcagctacga tgaatcagct ttttgcagcc
    39121 tatgcacaag gaaaacaggc aaaagaatta gccgtagttt taggtgaatc tgctttatct
    39181 gatgtagaca agatctatgc gaagtttgct gagcggtttg aaaaagaata tgtcaatcaa
    39241 ggattctaca cgaaccgttc gattactgaa acacttgatc tagggtggga actgctatcg
    39301 atgttgccaa gaaccgaatt aaaacgaatc aaagacgaca tgctggacaa atatctgcca
    39361 gaagggaagt gagttctgat ggcacgattg aatgtgaatc cgacccgcat ggaattgact
    39421 cgattgaaaa aacagttgac aactgccaca agagggcata aattattaaa agataagcaa
    39481 gatgaactga tgcgtcaatt catcctgttg attcgaaaga acaaccagct gcgtcaagaa
    39541 atggaagagt ctatgacaga agcaatgtct gattttgtat tggcaaatgc ttcgatcacg
    39601 gaacctttca tcgaagaatt atttgttttg ccggcggaaa acgttgattt gtctatcgta
    39661 gacaaaaata tcatgagtgt aaaagtacct gtgatgaatt ttgaatatga tgaacagctg
    39721 acagacacac ctttggaata cgggtatttg aattccagtg ccgaactgga tcggtcaatc
    39781 gatcggttta ctaccctgct tccaaaactt ttggaactga cagaaatcga aaaaacttgt
    39841 caactgatgg cgagtgaaat cgaaaagaca cgtcggcgag tcaatgcatt agaatatatg
    39901 acgatccctc aattagaaga aacgatctat tatattcgta tgaagctgga agaaaacgag
    39961 cgcgcagaag taacaaggtt gatcaaagta aaaaatatgg gtaccactga ctaagtggta
    40021 tcttttttta aaagaggaaa acgatgatta aacaaagcaa acaaataaag aaacgtttgc
    40081 cggctgttca gcttctcgca ttaggatttt ttctcctgat tttagttggc ggcggcctac
    40141 ttaccctacc attttttagt aatagtgggc atgggacaaa ttttatcgat gcgcttttca
    40201 ctgcaacttc tgctgtctgt gtaacgggat tgacaacatt gaatacagca gagcattgga
    40261 acagtgctgg tcaatttttg atcatgcttt tgattgagat cggcggtctt ggttttatga
    40321 tggttccgat tctatgcttt gcattgataa agaagaaagt cagtctcagc acacgtatta
    40381 tattaaaaga agcgctgaat ctagaagaag tatcaggtgt gatgaagctc atgctttaca
    40441 tcctaaaatt ggcctttgtg atccaattga ttggtacggt tgctttatct tttgtatttg
    40501 tgcctgaatt tggctggttg aaaggtatct ggtacagttt gttccatgca atctctagtt
    40561 tttgtaatgc agggtttgat ttgttaggag acagtttagc caatcaccag caaaatgttt
    40621 atttgatcat ggtggtatct gctttgatca tttctggtgg gttaggcttc atcgtatggc
    40681 gtgatttact ggaatatcat cagaaaaaga agatgacgat tcattcaaaa atcgcattaa
    40741 ccgttacagg taccctttta ttaggcggat tcgttgtgtt ctttttcaca gagcgcaatg
    40801 gggcaacgct agtggaaggg aatatgtttc aacgattggc aaacaccttt tttatgagtg
    40861 tgacacctag aacggctgga tattattcag ttgattacct ccatatgagc catgcaggtc
    40921 tgattttaac gatgtttttg atgtacatcg gcggaacatc tgggtcgacg gccggcggat
    40981 tgaaaacaac tacgttaggt gtgttgctga tccagatgcg ttcgatgttg aaaggacgta
    41041 cgagagcgga agcatttggc cgtaccatcc gacaaggcgc agtgttgcgg gcacttactt
    41101 tattttttgt tacgttgacg ttgtgtgtag tcgccatcat gattttatcg gtgactgaaa
    41161 cgatacctaa aacttctggc atcgaatata ttgcttttga ggtcttctct gcgtttggta
    41221 cagtaggtct tacgatggga ttgacgccag acttgactgc aatagggaaa ttgatcatta
    41281 tagcgcttat gtacattgga cgagttggtg tattgactgt ggtcttctct ctgatgacaa
    41341 aagcacaaag aacacaatca aaatacaaat atccagaaga aagtgtcatg attggataat
    41401 ttcatcttct gacagaaacc tagtgattta gtaaaataag aaaataaaat aatttttctt
    41461 gcttcttgga tactttaagt gcaaaatgtt cgtttatttt ttgaggcact acccgttgtt
    41521 gaacctcggg tagtgcctct tttttattga aaggaatcaa taagatttga ttcctttatt
    41581 tatcaatagg ttataattca tattttttta ttttttcttt tacgatactt agtccagaag
    41641 ctaaaatttc aaggttatta gaggataggg aaattcgaac gaatgcatct ggttgcgtac
    41701 gtgtagtaaa gcgtctggaa tgataaagtc ggataccgtt agcaagaaag tcattctcaa
    41761 ttatcttagg gtcaatctca ggatcaactg gaagaattcg atagtaaggg acacgattcg
    41821 ttggtttttc tactttgaaa agagaatcaa aaagctgatt ggctcttttt gtaagactta
    41881 atttagtttc taagatccta tttgcttcat ttgaatggag gatttgagtg atgacttcca
    41941 catctaatcc agaagttttc acatttatat taaaaattgc ttgttctatc ttgctttgga
    42001 catgtactgg aactacaaga taagcaactc gcaatccaga acaaataaat tttgtcattc
    42061 cagctaagta gattgtttgg ttaggtaata aattttggaa aggaggaatg atcgtatgtt
    42121 gatagtaagt tgttaaaaat gaatggatat catcttcaat aacccataga ccttcttttt
    42181 caatcacttc ggctaattgc tctcgtcttt tgtgagagat ttgaaaccct ataggattat
    42241 tacaagaagg cataagaaag acaccatgaa tcttcttttt tctacattcc tgaatcaata
    42301 tatcaggtcg cattccttgc tcgtcaaaat caattggaac gatctctaaa tgatataact
    42361 gagccaattc aatgaaatta gcgtatgtat atcggtctgt tgctattcta tcacctggag
    42421 agaaaagtgc agaaagtgtg atagccaatc cattttgaac accggaaaca atagatagag
    42481 attctaagga cggaatgact ccttgagttt ttaaccaatt tgctgcagta gtcaattgaa
    42541 aatttgtgcc tttgggatct tggtaattaa gcaaaccaac aagatttggg ttattactag
    42601 ttgattgaat aaacgggaca acgaatttat tacattcttc aaaagaacta accagaccaa
    42661 aatcaatgat atgttcggtt acttcattgg tagagatggt gatggactca aagacattgg
    42721 gagaaataaa tgtgccactt ccaatattcg tatacagcaa acctttctca attccatatt
    42781 tataagcctt gccaacggta gtaaaattta aatctaaata atcagctagc tctctttggg
    42841 agggtaactg agtgtttttc tgtaatttat tctttaaaat atcttgttct aattgttgaa
    42901 tcaacgatcg ataataagga cgcttcaatt tttgtttgtc tggtcgccaa gttaacgggt
    42961 aattgtcata agaattaata ggcattttct ccactcctta aaattgtata ccatacaatt
    43021 ttaccattga ttgtattgat tttagaagtt aatcttttgt gaggagggaa ttgtctatga
    43081 aaattattaa ttttgaggaa gtagtagctt cttttagttt tgaagaagcg attcaagtaa
    43141 tgaaaaaatg tttttttgat tatgaaagtg gtaaaatcag ccaaaatcct cgattggtgg
    43201 aaattttacc tgacggaaaa ggcaaaaata tgtttgcgat gatgcctgct tatttggggg
    43261 agaacagata ttttggcaca aaagtcatta ccgcttttcc ggataatcat cagtatcatt
    43321 taccttctca tttaggagag attttcttgt ttgatgctca aaacggacta cccaaagcat
    43381 tgataaacgc aaatgcagtc acctggattc gaacagctgc tgtatctgcg ctggcaacag
    43441 attacttagc aaatccgcat gcagaaacac ttgctttaat tggagctggt caacaagcat
    43501 tgtcgcattt gactgcgatt tctaccattc gtcccatcac tacagtgttt gtttacgata
    43561 ttttagaaga aagacgaaat acttttatcg ctaaagctaa aaaacagtat cctaaaataa
    43621 cgtttataaa tgcaatatca gtagaagatg cagtacgtcc agcggaaatc atttgtacgt
    43681 tgacctctag taaagaggca tttcttcaaa aagagtgggt aagggaagac gcacatatca
    43741 atgctgtggg cacatttact cctgatacaa gagagataag tacatcgttg atggaaactt
    43801 ctcaaatcta tgtagatgat tactcagctg ccttaacaga aagcggggac ctgcttatag
    43861 ccatggcaga aggagattta gaggaatctt gtattgttgg tacattaggc gaattagttt
    43921 ctgagaaaaa aacattttat aaaggagaat cgaggccgac gattttcgac gcagttggtc
    43981 tagctattga agatctttgt tgtgcagaat atatttataa caaattagag aaaggggctt
    44041 taaaatgaac ttagattatt acgtagttga tgcatttgca gatgaggtgt tcaaaggaaa
    44101 tccagcagcg gtttatgtgc tagaagaatg gctgccagaa ggtacgatgc aaaaaattgc
    44161 cattgaaaac aatttatctg aaacagcatt tacagtgaag aaaaaccaag aatttgagct
    44221 tagatggttt acgccagatc gagaaatcga tctttgtggt cacgcgacat tagcaacagc
    44281 atttgtttta tttaactatt acaaaatacc tgatgaaacg attaaatttt ctactcaaag
    44341 cggtaatcta tttgtgacaa gaattaaaga ttattattac atggattttc ctagtattat
    44401 gccgaaaaaa gtgccgatat tgtctgaata tgaagaagcg attggggcta agattaaaga
    44461 agcctactta gcacgtgatt tatttttcgt attagaagat gaaaaaacgg tggctaaatt
    44521 gcagccagat tttacagcta tcaaaaattt tgaattagga ataggagtca tcgtgacagc
    44581 agaaagtgtg caaaaagact ttgtttctag aaccttcttt ccaaaattaa caatcaatga
    44641 agatccagta tgtggatcag cacattctaa tcttattcct tattgggcag aaagaatgaa
    44701 taaaacaaaa ttgtcagctt atcaaatgtc atcaaggggc ggggatctag aatgtgaatt
    44761 aaaagaagat cgtgtgataa taggaggaaa agcagttttg ttttctaaag gtacctcgtt
    44821 tatttgattt ctttcaaatg aattaaaaat aaattggtgg agagtggcaa ccttatagct
    44881 acaatggttg ttaaaaaaag acgcaaactt tttcaattta atgaaaagtt tgcgtctcat
    44941 tttaattatt ggtgtttgtt ttttattcaa tcaagagtaa aatgccccat actaactatc
    45001 ctcggatgac ttcgatttta taaccatcag ggtcaatgac aaagtagtaa gaaggcgcag
    45061 tgccaggtaa tccttttaag tcagtaatct caagaccagc agctttatgt tgctcgtgta
    45121 atttttctag atcatcagct gctatagcga tatgaccata gccgtctcct agatcatacg
    45181 caccatgatc atagttgtaa gtcaactcta attcatagtc atccccagga agtgtcaaat
    45241 aaacaagtgt aaatttgttt tctggaaaat cacggcggcg gctttcttca aaaccaaatg
    45301 ccttttgata aaattcgatt gatgcttcaa gatctttcac tcgaacacat gtgtgagcca
    45361 ttttcataga ttcatctctc cttttccttt tactcaatca taacaaaaag aagtaaggaa
    45421 atagttgatt tgtgcttgtt catgagaaat ttctcatgta aaatggatag aaaataaaac
    45481 tgttaaggtg gaaactattc atggataaac caatttttgg tgaaaaaaag caatttgctg
    45541 attatcaaac ccgttatgca gcatatattg tcatagaaag agatcagcag attgcagtaa
    45601 tcgaggctcc aaatggtgct ttttttcttc ctggcgggga aattgaagga gaagagacga
    45661 aagaagaagc gattgtccgt gagctgatag aagaaatggg aattgtggca gaaatttctt
    45721 cttatctggg agaagctgat gagtattttt actcgaatta tcgtgcaact tattattata
    45781 atccaggata tttctttgtt gctgattctt ggaagcgtat aggagaacca actgaaaaga
    45841 ccaataaaat ttggtgggtg agccctcaag aagcgcttgt gaaattgaaa cgtggtagcc
    45901 accgatgggc agtcgagaga tggatcgaaa aaaataaaaa ctgaaagaaa gcgagtagat
    45961 cagctttctc tcagtttttt tatttattac agtacatatt ttttgattgc ttcagctaca
    46021 ccgtgctcgt cgtttgatga agtgatgaca tttgctgctt ctttgacaag agaaacggca
    46081 tttcccattg ctactcctag accagcatat tcaatcatgg ataagtcgtt ctcgttatct
    46141 ccgatagcca tgatttcatc ttgatcaata ccaaggtgct gtgcgagatt cgcaactgcc
    46201 gcacctttac ttgcttcttt atttagtact tcgaagtaat agggcgcact tttgaccgtt
    46261 gtgtatttat cacggaaagt ttgcggtaaa cgcgcaattg ctgcatctaa aatttctggt
    46321 tcgtcgatca tcatcatttt gacgatgttc atgtctggtg tcatttcttc aggtgttcga
    46381 tattttagcg gcatcttgac taaacttgct tcgtggatcg tataagcgct gatatctcga
    46441 ttaggcgtgt agatcgcttt gtcatcgatc gaatggagat gactgccgac acggcgtgcc
    46501 atcacttcga tctctaggaa atcttcatgt gtcagtccgt gacgggcgat gattttacct
    46561 gatttcgttt gttgtacgag tgccccgtta taagtaataa cgtaatcatt atcttgaaaa
    46621 aggttcaact cgtttaactg ttcctggaca cctggtaagg gacggccagt gcataaaacg
    46681 atcgaaacac cttttgcaac agcagcggca atcgcttctt ttacttcttt tgttacttct
    46741 cttttctcat ttaataaagt accatcgatg tcgatagcga ctagtttgat agacataatt
    46801 tcctccaata tattttaatt tatttcaatc aatgcgccat tacggatatg gctggcaaat
    46861 tcttgataag tttcgtcaaa taaatcataa tgatcacgca aggacggatc aaccatttct
    46921 tttggaaaga aaaatcgctc atctccttgt tcttgtcccg ctaatgcagc aacaagctga
    46981 ctaacctgtg ataattctat caaagttccg tcatttcgca aaatctcgat ttgtgtgcga
    47041 tgtctgcctt gttctgggcg ataaaaatca taaggtagat cgtagctaga attcacagca
    47101 gtgtaataaa caggattata tccgaccttt tctactaaca aagtgagttc ttggactaat
    47161 tttgaatccc ggttgccaga aaaagtagca gatttcagtg gtttacgatt caaaaaacgt
    47221 ttagctaaat catttaaaat aggatcagca gattcagacc attgagtaaa gtaagtgccc
    47281 aagaccccat catcaagttt gaggtattct tctaaagtaa agcttccgtc aagaaatggc
    47341 agaagtaatt gagaatggag ttcaaaactg ctggcatctt cttgatacaa ctcgtgtgcg
    47401 cgatgaagca gatgctccaa aattacttcc ataccacggg aaacaggatg gaagtacact
    47461 tgcacataca tttgatatcg gctaacgata taatcttcca ctgcatgcat gccactcatg
    47521 gaaaaagcga tcccgccttc ataaggacga atcacacgta atattcgggt aagatcaaat
    47581 gttccatatt ctgttccagt gaaataagca tcccgaagca aatagtccat tcgatctgca
    47641 tcgatctgac tagaaatcat ttggacaact tgtgggttgg ggtaagtttt ttggatcaca
    47701 ctagctacct tttcaggaaa accttcttct actcggttaa gaatctgata cacttctgtt
    47761 tctggagaag tgatgatctc tacagtgatg gcttcatgat tcgtatggaa gatatgttca
    47821 aatgtatgag agtaaggacc atgaccgaca tcatgcaaca gtgccgcaca taaagtcacc
    47881 agccgttcct gatcatccca gcctccgttg cctatttttt cttttgaaaa atttcgagaa
    47941 aagatatcgc agattcgtct tgaaatctca taaacgccta atgaatgagt aaaacggcta
    48001 tgttctgctc cgtgaaaagt gaaagaagaa gtgcctaatt gtttaatgcg tcgtagacgt
    48061 tggacttctt tcgaattgat caaatctaag attacttgat gctggacatg gatatagtta
    48121 tggactggat cacgaaaaac tttttccata ggcagcattt gatatttata aggggttgtc
    48181 ataatgtagc tcctttatgt tattacgttg ttccattctc tggatttggt tgttccattg
    48241 ctccagctgg atttcttttt ttagccagtc ggtagaatcc tgtaaatcac ttgcagaata
    48301 cagcttttca aaagcttttg caaatgcttc tttgacttct tttacaaaaa ggggttggtc
    48361 aagcagttct tcaagtgttg ccattgtagc aggatccact gcaggatagc catttgtacc
    48421 aaagtcttct tttaaagcag attgataaaa tcgcttcatg acttgcccgc gtttttcctg
    48481 attaccgttg acacttaagt acatcataac agaaatccca tttttgatcc gacgctgagc
    48541 gataccggca aattttttgc catggatgct taaatcataa gttccaggac aataagaatg
    48601 ggtgatttcg aatgcttgta tcggtgcctt tggaaaagcg tatttagtca ataggagcat
    48661 ttgctcgtaa gcgtcatcta tggttatttt ttttgtgtca ctttggggga aaatcaaaga
    48721 aatattcaaa attccttcat ctgatacgat ccctaatcca cctgaatttc tgatcactgg
    48781 agcgtaacct gcatctttca gtgtttggat cccgtcactt agaaaaggag ttcgaacatc
    48841 cttcatacct aagatgactg tgcagtcata ttgccagaaa tgtaaaaaga tttgctggtg
    48901 ttctttagaa tattccgtta atatatctgt taatgcaaaa ggggaaaagt cgtttttttg
    48961 ataaatgtgc tgatctagtc gaatcgcagg gttcattcaa ccggctcctt tgtataaatt
    49021 catattttct acaatattat actctaaaat caaagagttg ttttggaaaa aaggttttct
    49081 gtaaaaatgg acaagttggt tgacaaaaca aaagaaacta ggaacaatgt agctatgaga
    49141 agtaaaggag aatgaataat ggaattatca caaggaacac cgatttcaat caaattgcgt
    49201 acaaaagtaa aacagcaagg ggaagtgcaa gatttttatt ttgatttgaa agggcaaatg
    49261 gtgacaattg gcgatacgct gtacatacgt tataaagaga ttcaggagga gacgggcgat
    49321 gagattcctg taacgatcaa attagttcca gatggtcatg tacagctgat ccgtgcagga
    49381 gaaatgcgga tgcgtttgaa atttggctat aaagaacggt tagaaacatc ctatcgaaca
    49441 ccatacggta tgatccagat tgctactttt acgaaagaac tgcatgttag tttgaaagac
    49501 cgtcccacag cagggaaggt tcgaatcgat tatgatctgt tcatgggacc ggaaaaaatc
    49561 ggcgaatatt atttgacctt ggattttaca gcgtaaatat aaaagaaaag tttgattttt
    49621 tgtgtctgat tttgtatgat aaggagtaga ctgtgaaagg acgtgtcctg attggaaatt
    49681 agtgtatttg aaggtgcaaa caaaagcgaa ttatcaatga tcgaagtagc acacgcgatc
    49741 ttagaacaac gtggcgatgt catggatttt tctgatttag ctaaccagat ccaaaactat
    49801 cttgggaaat cagacagtga aattcgtgat tcactcgcac aattttatac tgacttgaat
    49861 attgacggca gctttatctc attaggggat aatcgttggg gcttgcgttc atggtatgct
    49921 atcgattcga tcgatgaaga agtaaaccat ggaatggacg aagaggatga agatactcca
    49981 cgtcgccgta aacgcaagaa agtcaacgcc tttatcaatg atgatgaaga cgcgatcgat
    50041 tacaatgacg atgacccaga agatacagat ctgacagaag aagatgacga tgatctgttt
    50101 gatgacgatg atgatgaaga tgaagaaatc gctgcttata attctgactt gcaagaaatc
    50161 ggagcagatg acccgacaga tgatgaagaa gacttgccag gaaatatcga agaagattta
    50221 agtatcatag acgaagacga tgatgatgaa gattatgaag aggaagaatt ttctgactct
    50281 gaaaaagaat aaacattatt ttcttacgag aggttgtgac agagacgatc agcctatcag
    50341 aataaggagg tgtgacacga tttttgtcac accttctttt ttgtatataa aaatcccaag
    50401 taaatacata aaaaataaaa aaattgaaac ttttagcgca ccttgtacgt catattaagt
    50461 gaggcagaaa ggagtggaga atgattttta ctggatataa gaaaaaacgg cagatcgaaa
    50521 aataccgtca cctgctgaat ggactcatcg aaactgatta tcaaaaaatg ttccgtatca
    50581 cgatgaatta cgtacatgat aaagaagagg ccttagatgt gatgcaagat agttttcata
    50641 aagccctgaa ctattttgaa aaagaaaaag agatcgagca ttttagtgca tggttttatc
    50701 ggatattgat ccgcacggca ttagatagtt ggcgcagaca aaaaaggacg cctgtggact
    50761 tatttgaaat tcaagatatc ccccaacagt tacctttaga aacttccgtt gcagagctcc
    50821 atatgatttt agataaaata gacagtccgg aaaaagagat tctgatcctc tacttttttg
    50881 aaggatttcg tttgaaagaa attgcgacta tcttggatat gaatgaaaac acagttaaaa
    50941 cgaaaatgta ccgctcattg aatgctttac gtcaaatcct agaatgaagg agagaagagt
    51001 gccatgtatt cccaaaaaga aaatttaaaa aaactaaaga aaacttataa agaacaagca
    51061 attcccaaag ggcttaaaga ggagatccgc cagcgtttta ttatcgaaga gcaatcattt
    51121 ataaaagcaa agcggagaaa gagacgtctc caagggttcg gagtatcttt ggctatcgta
    51181 atgattacaa caagtagcct tctttttaat agtcaagttc gaagctttgc agaagattta
    51241 cccatcttag gatcagtcat tgaattgatc ttaggcgaac gctttactga tcgatctgaa
    51301 aaaatcgata ttcaggtacc gaagatcaat acacaaaatg agaaagaaaa taaaacaatt
    51361 catggattaa atcaaaaata ctttcgcgaa ggacaagcag attttgaaaa agctgaaaaa
    51421 gaatatggaa attttgaaac ggatcattac caagttttgg gagattatca gaaaatcgta
    51481 gacgataacc ggtttctcgt gattgaaagg cagatcaccc aaacagcagc agatagccat
    51541 gttgaaaaaa gatacgacac aatcgacaag aaaaacagtg tccagctctc acttccactt
    51601 ttattcaaag atgacaccta tctatctgtt ttgacaaaag aagtcaaacg gcagatggcc
    51661 gaacaagtca aggaagatcc atctaagtac tattggactg agcaagatat tcaagaaggg
    51721 acgatagaaa aaccaacact tgttacgcct acacgaagtt tttatttgaa caaagagcat
    51781 caattagttt tgactttttc tcaatacgaa attgctcctg gttatatggg tacaccagaa
    51841 tttgtcattc ctaagtccgt gacaaaaacg attttggcat cggaagatta tttggatcat
    51901 tagacgagaa gtagttgcga ctagcagttt caattttcaa gtaagtacaa gtaaataata
    51961 agaagagaaa aagagaaaga agagatatag tgaaaagaaa ttatttagtt atcagtatta
    52021 ttgctttatc cgtgcttttg tttttcgaaa ttacttcggt ggcctccttg atcaccgaag
    52081 taaaaggaca aacacactct tcggagcatt cgtcacaatc tttcaaacaa tcagaacaat
    52141 caaccattaa aagccaatca actgaaacag ctaacgtcaa agaagccatt caagaatcag
    52201 cggaaaaggt acaaagtcag tcatcacaat caacacaaga cagtacaaaa acgagccgag
    52261 atccggctgt caaaagcgtc gcaatcagct ttgatgatgg accaggagcg accacaacac
    52321 cgcagcttct gcgaatctta aaagaaaaaa acgtgcatgc cacttttttc gtcttaggag
    52381 aaaatacggc gcagcatcct gaaatcgtga agcagacagc tgaagcaggg cacgagattg
    52441 gcaatcacac atacgatcat cagaatctgg ccactctttc tgcccagtcg atgacggagg
    52501 aagtgacgaa agcagacact gagatcaaaa aagtcactgg caaaaccccc acttttgttc
    52561 gtccgcccta tggttctgtc acgaatgtag gagcaacgat catccagcga ccgatcatcg
    52621 aatggtctgt tgattcagaa gattggaaga caagaaatcc tgatttgatt ttgcagaaga
    52681 tccaagcaac agtatacgat ggggcaatta ttttattcca tgatatctat cctgaaacga
    52741 ttcgtgccgt tcctcaagtg atcgattatc tgaaagagca agggtatcgc atcacgacag
    52801 ttggggattt attagggcat ccaacggctg tcgagaacta ttatggcaga aacgatcatc
    52861 ggccagttca gtaagtgaga caagtatctt taataaataa cacattttaa taagtagttg
    52921 aacacataac taccttactt gcaaaggctt aacaatatct atacaggtac aacaaaaaac
    52981 tgtccaccaa ttttctttgg cggacagttt tcacttaaaa ataaagaagc aactattcgt
    53041 aaattatgct aaaatagcag tagaacgcgt cctgagggaa tcgaaccccc gtctcaagaa
    53101 ccggaatctt acgtgatatc cactacacta aggacgcaag cactgggata attgtaacta
    53161 aacagataaa aaattacaag gggattggac aaaaaaatga aatttgagca aaatttttca
    53221 caaaaacagc agcagacaca gaaactagcc atgacgcaac agttgcaaca gtccatccaa
    53281 gttttacaat ataacagtga ggagctgttg gcattcgttg agaatcaagc aatggaaaat
    53341 ccattggtgg aagttgttga gccggaatgg cagccagatt acataaaagc ttcttcatct
    53401 tcttatgaag gagaagagac aaattaccta aatcagattc ctgatacaaa agggtcttta
    53461 tttgattcat tgatcgaaca agtccatttg aattaccgag atactttttt gaggaaaatc
    53521 gttctttatc ttgtagaata catcgatttg aacggatttt tgacgattag tttagaagaa
    53581 gccggaaaag agattggagc tacgcctatc caaatgctcg atgcgttgac tctgattcag
    53641 caattagaac cagctggagt aggtgcacgt agtttgcaag aatgtctcat gcttcaaaca
    53701 gaacgagatg attatgcgcc ggaattagct tatatcgtgt tggaagaatg ttttgaggaa
    53761 ctggtggagc gaaaatggaa agaaatcgca caacgttttt ctgttgatct acatgctgtt
    53821 cagcagatat tcgactattt acaaacgttg agtccaagcc ctggccggat tttcgaccgt
    53881 agcagcgaat tgtacattat tcctgatgtc cgggtattag tggacgacga taaaaatgta
    53941 caagttatct caaaccgaaa aaatcagcca aatatacgct ttcaagagag ttacttcaaa
    54001 caaatgtcac aacaagcaga taaagaaact gaaaattatt taaaagaacg gaaacaggaa
    54061 ttcgaatggt tgaagaaaac gatcctacaa cgtggggata caattttgcg ggttgctcaa
    54121 gtcattgttt cccggcaaaa agctttcttt atcgacaagg aacgtccaat caagcctctt
    54181 acgttaaagg aagttgcaac tgagatagat gtgcatgaat ccacggtcag tcgtgcagtc
    54241 aacgggaaat atttggaaac agacttcggt gtatttgaat taaaaaaatt tttcactaca
    54301 cgaattccta cgaatagtac agaacagaca gaagaccttt cagcagatac agcgaagaaa
    54361 aagctgcagg aattagtcga tcaagaagac aaaaacaagc cgttgtctga ccagaaattg
    54421 gttgaattgc tgaaaaaaga tgagatagcg atctcaagac gaacagtagc aaaatatcgt
    54481 gatttattag gaatcccgag ttcatcaaaa agaaaacgtt atgataacta atcagtcaaa
    54541 agactagaaa aagtatttca ctttttctag tctttttagt tgaaaaacga gagcaaaact
    54601 gttagactta cagtcgtgag gttgagattt ccctttattg atgtgaaatt cgaatagtta
    54661 atttcttttt ttatcgtata tgggtcgttt taagtctaca ttggacgtaa agtgtccaac
    54721 taaggagatc gctatgctgg atgaaataaa aatgattgaa tctgttgcac cagatattat
    54781 cgaagtgttg caagaacgct ataaaatttt acgaaatatc tattggatgc agccgattgg
    54841 acgtcgaagt ttatcggaaa gtatggggat cacagaacga gtattgcgaa cagaaacaga
    54901 tcttttgaaa aatctgaatt tgatcgacac ctcaaaaagc ggtatgacgc tgacaactaa
    54961 gggcgaagaa gtttatcaaa gccttgaaaa cttcatggat cagcttttag gtacgcatca
    55021 aaccgaacaa cagttggcag aatattttgg taaccaacgc tgtatcgttg tttcaggaaa
    55081 cagcgaagag cagaccaaag tggctgatgc attcggcgaa gcgctgagcg aagccctaga
    55141 ccgactactt ccagaaggcg agaatatcat cgctgtgatg ggaggaacta ctatggctgt
    55201 ggtagccgaa caattgtcta atctggaaaa taagaaacgg cataacctgt ttgtccctgc
    55261 aagaggcggg attggtgaag cgataactgt acaggcaaat tctgtcagtg caagaatggc
    55321 tgctaaagca aacggtaacc accgtgcact ttatgttccg gaacaattaa gtctggcaac
    55381 ttacaattct ttactcaatg agccatctat ccaagaagtc ttaaacttga ttagtgaagc
    55441 gaattgtgtt attcatagta ttgggcgtgc attacacatg gcagcacgtc gtaagatgac
    55501 tgaaaaagaa ttagtcatgc tgaaacaagc aaatgctgtt gcggaatctt ttggctactt
    55561 tttcaatgaa aaaggtgaag tcgtttataa ggtccctaga atcggcatag aattgcaaga
    55621 tttggaaaaa gtcccgatca tcatggcaat cgcgggcgga aaatcaaaag ctaaagcaat
    55681 tcgagcttat atgaaaaatg caccaaaaca aacgtggctc atcactgatg aagctgctgc
    55741 aaatgagatt ttaaaagggg taacccttta aaataaatat ttttttgatt ttcataagga
    55801 ggaaatctta aatgacagtt aaagtaggta ttaatggttt tggacgtatt ggacgtctag
    55861 cattccgtcg tatccaagat gtagatggaa tcgaagtagt agcaatcaac gacttgacag
    55921 atgctaaaat gttggcacac ttgttaaaat acgacacaac tcaaggacgt ttcaacggaa
    55981 cagttgaagt tcatgaaggt tcattcaacg taaacggaaa agaagttaaa gtattagcta
    56041 accgcaaccc agaagaatta ccatggggcg aactaggcgt agatatcgtt ctagaatgta
    56101 ctggtttctt cacttctaaa tcagcagctg aaaaacattt aacagctggt gctaaacgcg
    56161 ttgttatctc tgctcctggc ggaaacgatg ttccaacaat cgtttataac acaaaccacg
    56221 aaacattaac tggtaaagaa acagttatct caggtgcttc atgtactact aactgtttag
    56281 ctcctatggc taaaacattg aacgacaaat ttggtgttgt tgaaggatta atgacaacta
    56341 tccacgctta cacaggtgac caaatgactc tagacggacc tcatcctaaa ggtgacttcc
    56401 gccgtgcacg cgctgctgct gcaaacatcg ttcctaactc aacaggtgct gctaaagcta
    56461 tcggtttagt aattcctgaa ttgaacggta aattagacgg agctgctcaa cgtgttcctg
    56521 taccaacagg ttcattaaca gaattagtaa cagttcttga aaaagaagta actgttgacg
    56581 aaatcaatgc agcaatgaaa gaagcttcaa acgaatctta cggatacaac acagacgaaa
    56641 tcgtttcttc agatatcgtt ggtatgactt acggttcatt atttgatgct acacaaacta
    56701 aagtaatgac agttggcgac aaacaattag ttaaaactgt tgcttggtac gacaacgaaa
    56761 tgtcatacac tgcacaatta gtacgtactt tagaatactt cgctaactta taagatagac
    56821 aaacgtacaa gtgtaaatta tagacatgta catttaaaag cggggaagca atcgcgcttc
    56881 ttccgctttt tttgataata agtttattca ggaggaaata aaatggctaa gaaaacagtg
    56941 aaagatatcg atttaaaaga caaaaaagtt cttgtccgtg ttgacttcaa cgttcctttg
    57001 aaagacggcg tgatcactga cgacactcgt atcaaagcag cattgccaac aatcaactac
    57061 gttctagaac aaggcggaaa agcaatcctt ttctctcacc ttggacgtgt aaaaacagaa
    57121 gaagataaag aaggaaaatc tttagctcca gttgcaaaac gtctaggcga attattaggt
    57181 aaagaagtaa cattcgtacc tgaaactcgc ggagaacaat tagaagaagc aatccgcaac
    57241 atgaatgacg gcgacgttgt cgtattcgaa aatacacgat ttgaagatat tgacggtaaa
    57301 aaagaaagca aaaatgatac agaactaggt aaatactggg cttcattagg cgatgtattt
    57361 gttaacgatg ctttcggtac agctcaccgt gcacatgctt ctaacgtagg tatcgcttca
    57421 actggtatcc caacagttgc tggattcttg atggaaaaag aaatcaagtt catcggtgaa
    57481 gcagtagaag aaccaaaacg accaatgatt gcaatccttg gtggcgcaaa agtttctgat
    57541 aaaatcggcg taatcgaaaa cttgattcct aaagcagata aaatcttgat cggtggcgga
    57601 atgacttaca cattctacga agcaaaagga atcaagatcg gtaactctct agtagaagct
    57661 gataaagtgg aactagcaaa agaattaatc gaaaaagcag gcgacaaact tgtcttgcca
    57721 atcgacaatg tctgtgcacc agaattttca aatgatgttg aaacacaagt aatcgaagga
    57781 gacattcctg atggtttgat ggctttagac atcggcccag catcagtaaa attatttgct
    57841 gatacattac aaggtgcaaa aacagttgtt tggaacggac ctatgggtgt atttgaaatg
    57901 agtaactttg ctaaaggtac aatcggtgtt tgtgaagcaa tcgctaactt agaaggcgca
    57961 acaacaatca tcggtggcgg agactcagcc gcagcagcag aacaattagg atttgctgac
    58021 aaattcacac acatctcaac aggtggcggc gcaagcttgg aattgcttga aggtaaagaa
    58081 ttaccaggac tagcagcaat caacgataaa taaacgacca agtttgctca attctgacga
    58141 gtaatcgaac aaaaggtgaa gggagttttc atgactccct agccattttt caataaatta
    58201 aggagtgtgt tcctcaatgc gtaaacctat tatcgcaggt aactggaaaa tgaacaaaac
    58261 tgcatcagaa gcaaaagaat ttgctgaagc agtaaaaaac aaaatccctt caaatgacaa
    58321 agttgattca gtcatcggat ctcctgcatt attcttacaa gaattaatga catcagctga
    58381 aggtacagaa ctaaaaatct cagcacaaaa ctgctactgg gaaaactcag gtgcgttcac
    58441 tggtgaaact tcaccagcag ctcttgctga tctaggtgtt cattatgtga tcatcggaca
    58501 ttcagaacgt cgtgaatatt tccatgaaac agacgaagac atcaataaaa aagcgaaagc
    58561 tatctttgca aatggtatga caccaatcct atgctgtggc gaatctttag aaacctatga
    58621 agcaggcaaa actgctgaat ggatcgaagg acaaattaca gctggtttag ctgatctttc
    58681 agctgaacag gtgtcaaaca tggttattgc ttatgaacca atctgggcaa tcggtactgg
    58741 taaatcagct gacgcacaaa tcgctgacga aatttgtgga gttgtacgtc aaacagttga
    58801 aaaactttat ggaaaagaag tatcagaagc agttcgtatc caatacggcg gttctgtaaa
    58861 accagaaaat attgctgaat acatggcaaa agaaaatgtt gacggtgctt tagtcggtgg
    58921 cgcaagcttg caagcagatt cattcttgtc attgttagac gctgtaaaat aattgttgaa
    58981 aatttgcgaa aaatgcaaga aatgtttgca ctaatgagca aaattaacta aaatcgtata
    59041 tgagggaaat cccttaggaa aaaacaaact caaaggagag acaaaacatg tcaattatta
    59101 ctgatgttta cgctcgcgag atcttagact cacgtggtaa cccaacaatc gaagtagaag
    59161 tatacacaga aagcggagct tttggccgcg gaatggttcc ttcaggtgct tcaactggtg
    59221 aatacgaagc agttgaatta cgtgacggag acaaagctcg ttatggcggt aaaggtgtaa
    59281 ctaaagctgt cgacaacgta aacaacatca ttgctgaagc aatcattggc tacgatgttc
    59341 gtgaccaaat ggctatcgac aaagctatga tcgctttaga cggaactcct aacaaaggta
    59401 aattaggtgc gaacgctatt ttaggtgttt ctatcgctgt tgcacgtgca gctgctgact
    59461 acctagaagt acctttatac cactacctag gcggattcaa cacaaaagta ttgccaacac
    59521 caatgatgaa catcatcaac ggcggatcac atgctgataa ctcaatcgac ttccaagaat
    59581 tcatgatcat gcctgttggc gctccaacat tcaaagaagc tctacgtatg ggtgctgaag
    59641 tattccacgc attagcttca atcttgaaag ctcgcggatt agcaacttct gttggtgacg
    59701 aaggtggatt tgctccaaac cttggttcaa acgaagaagg ttttgaagta atcatcgaag
    59761 caatcgaaaa agctggctat gtacctggta aagacgttgt tcttgctatg gatgctgctt
    59821 cttcagaatt ctacgacaaa gaaaaaggtg tttacgtact agctgattca ggcgaaggcg
    59881 aaaaaacaac tgacgaaatg atcaaattct acgaagaatt agtttctaaa tatccaatca
    59941 tctcaatcga agacggatta gacgaaaacg actgggacgg attcaagaaa ttaactgacg
    60001 tattaggcga caaagttcaa ttagttggtg acgacttgtt cgtaacaaac actcaaaaat
    60061 tatctgaagg tatcgaaaaa ggaattgcta actcaatcct tatcaaagtg aaccaaatcg
    60121 gtacattaac agaaactttc gaagctatcg aaatggctaa agaagctggc tacacagcag
    60181 ttgtatctca ccgttctggt gaaacagaag attcaacaat ctctgatatc gctgttgcaa
    60241 caaacgctgg ccaaatcaaa actggttctc tatcacgtac tgaccgtatt gctaaataca
    60301 accaattact acgtatcgaa gaccaacttg gtgaagttgc agaatacaaa ggtttgaaat
    60361 ctttctacaa cttaaaaaac aaataattct tttctaatga agatacatga tcgactattg
    60421 aaagatagtc gagtatgatc acttagttaa gtaatcgaac tctctacttg ctgaaatatc
    60481 agcaggtaga gagttttttt gcaactagct tctgtatatg atgtttacaa agaatggtac
    60541 aagaaaagat catccttgaa aaaggaaagc taacaataac tagcatcata taagagcttt
    60601 taaggataga acagtagaat aggaatctat gagcaagtcc tctcgtataa ataaaatagg
    60661 agggaagtag cagcatattt ttcataaagt ggctctcttt cttcattttt actttggttg
    60721 ctcctatttg aaaattcgag cacactcaaa tacaataaaa agaaatggca agggagagga
    60781 ttagatgaaa aaagaagaaa aaatcgcgat tttacaagag atcatccgaa ttaaatcagt
    60841 gaatggaaac gaaggtgaag tagcagccta tttgaataag cttttggcaa agcatgacat
    60901 aacaggagag attgtttctt acagagatgg tagagataat ttgattgctc gttaccaaaa
    60961 gggccaatca ggaaaagtgt taggcctatc tgggcatatg gatgtcgtgg cggctggtga
    61021 tgaatcgtct tggacctatg caccctttgc agcagaaatc catgggaacc gtttgtacgg
    61081 acgtggtgct acagatatga agagtggctt ggcagcaatg gtgattgcca tgatcgaact
    61141 gaaagagtca ggaaaaccat ttaacggaac agtcaaatta ttagccactg tcggagaaga
    61201 agtgggtgaa ctaggtgggg aacagctcac gaaagcaggc tatgtagatg acttagatgc
    61261 cttgatcatc ggagagccaa ccaattacag tttgatgtat acgcacatgg gatcaatcaa
    61321 ctatacagtc acctcgcacg gaaaagaagc gcatagctct atgccagacc aaggttataa
    61381 tgcaatcaat cacctaaatg aattcattac gaaagcaaat gctgaaatga atcacctcgc
    61441 tgaaacaatc gagaatcctg tcctaggaaa aacaatccat aatgttacat tgatcagtgg
    61501 cgggaatcaa gtcaacagca tcccaagcca tgcgcagctc caagggaaca ttcgatcgat
    61561 tccagaatac ccaaatgata aaatcattgc attgctgcaa tcaatcgtca atgaattgaa
    61621 tcaagagaca gactatcatt tggaattgat gatcgattac aacaaaatac ctgtcaaagc
    61681 tgatccagat tctcctttga ttcattgcat tcagcaacaa ttcagccagc cattaccttt
    61741 agttggagcg gcagcaacaa cggatgcagc cgaatttacg aaagctaacc attccttcga
    61801 ctttgtcgtc tttgggcctg gtgtcgttac tttgcctcat caagtagatg agtatgttga
    61861 aatcgataat tatttggata tgatcgaaaa atatcaagga attattttat cctacttagc
    61921 gtaagatttt tttaataaat gaaaaaacag agccagatta gcattattt
//
LOCUS       DACGEU010000007        60323 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.007, whole genome shotgun sequence.
ACCESSION   DACGEU010000007 DACGEU010000000
VERSION     DACGEU010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 60323)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 60323)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..60323
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.007"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            44..1411
                     /gene="nhaC"
                     /locus_tag="IXR40_000406"
     CDS             44..1411
                     /gene="nhaC"
                     /locus_tag="IXR40_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HAQ4360281.1"
                     /translation="MNKNISLKESIAVLIVLLALLGVLIIGFQLSPHIPILAAFMCLL
                     FYGRFKKFTWDEIHDGIIKGITPGIIPILIFLLIGVLVASWILSGTIPTIMVYGFKLV
                     SVRFFLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMTTGAVVSGAFL
                     GNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILGHNSHSADLAS
                     INEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALVLSFIHEKSLT
                     VGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGGLLIKYLIVDT
                     IVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSFDDVGLSKTYL
                     TRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFAFFSILAPVFTILGGFLLNR
                     RRVKN"
     gene            complement(1692..2711)
                     /locus_tag="IXR40_000407"
     CDS             complement(1692..2711)
                     /locus_tag="IXR40_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAQ4360282.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(2733..3740)
                     /locus_tag="IXR40_000408"
     CDS             complement(2733..3740)
                     /locus_tag="IXR40_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HAQ4360283.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            complement(3733..4398)
                     /gene="pgmB"
                     /locus_tag="IXR40_000409"
     CDS             complement(3733..4398)
                     /gene="pgmB"
                     /locus_tag="IXR40_000409"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HAQ4360284.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            complement(4391..6685)
                     /locus_tag="IXR40_000410"
     CDS             complement(4391..6685)
                     /locus_tag="IXR40_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HAQ4360285.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLSGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            6945..9110
                     /locus_tag="IXR40_000411"
     CDS             6945..9110
                     /locus_tag="IXR40_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4360286.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            9414..10247
                     /locus_tag="IXR40_000412"
     CDS             9414..10247
                     /locus_tag="IXR40_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HAQ4360287.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(10349..12049)
                     /locus_tag="IXR40_000413"
     CDS             complement(10349..12049)
                     /locus_tag="IXR40_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360288.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            12556..13716
                     /locus_tag="IXR40_000414"
     CDS             12556..13716
                     /locus_tag="IXR40_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAQ4360289.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            13732..14175
                     /locus_tag="IXR40_000415"
     CDS             13732..14175
                     /locus_tag="IXR40_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4360290.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(14658..15188)
                     /locus_tag="IXR40_000416"
     CDS             complement(14658..15188)
                     /locus_tag="IXR40_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HAQ4360291.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            15293..15844
                     /locus_tag="IXR40_000417"
     CDS             15293..15844
                     /locus_tag="IXR40_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAQ4360292.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            complement(15997..16470)
                     /locus_tag="IXR40_000418"
     CDS             complement(15997..16470)
                     /locus_tag="IXR40_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAQ4360293.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            16608..18080
                     /locus_tag="IXR40_000419"
     CDS             16608..18080
                     /locus_tag="IXR40_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAQ4360294.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            18077..18787
                     /locus_tag="IXR40_000420"
     CDS             18077..18787
                     /locus_tag="IXR40_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HAQ4360295.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            19139..19423
                     /locus_tag="IXR40_000421"
     CDS             19139..19423
                     /locus_tag="IXR40_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HAQ4360296.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(19740..20123)
                     /locus_tag="IXR40_000422"
     CDS             complement(19740..20123)
                     /locus_tag="IXR40_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HAQ4360297.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIK"
     gene            complement(20125..20709)
                     /locus_tag="IXR40_000423"
     CDS             complement(20125..20709)
                     /locus_tag="IXR40_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HAQ4360298.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            complement(20756..22231)
                     /locus_tag="IXR40_000424"
     CDS             complement(20756..22231)
                     /locus_tag="IXR40_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HAQ4360299.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            22412..22723
                     /locus_tag="IXR40_000425"
     CDS             22412..22723
                     /locus_tag="IXR40_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360300.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            complement(22838..25174)
                     /locus_tag="IXR40_000426"
     CDS             complement(22838..25174)
                     /locus_tag="IXR40_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAQ4360301.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            25316..25984
                     /locus_tag="IXR40_000427"
     CDS             25316..25984
                     /locus_tag="IXR40_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4360302.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            25987..27030
                     /locus_tag="IXR40_000428"
     CDS             25987..27030
                     /locus_tag="IXR40_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAQ4360303.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(27267..28148)
                     /locus_tag="IXR40_000429"
     CDS             complement(27267..28148)
                     /locus_tag="IXR40_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAQ4360304.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            28307..29035
                     /locus_tag="IXR40_000430"
     CDS             28307..29035
                     /locus_tag="IXR40_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HAQ4360305.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            29191..29508
                     /locus_tag="IXR40_000431"
     CDS             29191..29508
                     /locus_tag="IXR40_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAQ4360306.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            29501..30109
                     /locus_tag="IXR40_000432"
     CDS             29501..30109
                     /locus_tag="IXR40_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HAQ4360307.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            30125..30955
                     /locus_tag="IXR40_000433"
     CDS             30125..30955
                     /locus_tag="IXR40_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HAQ4360308.1"
                     /translation="MRLKHFLITGIGLMLTGGLLAGATYTLGAQKSLTWDNGPRLIDM
                     VTETKKIKDANKIVIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKK
                     STGAIISLEDTSAQITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSF
                     NEFTGGTITAKDELGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSL
                     HEMENSGYTIQTSGESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD
                     "
     gene            31093..31581
                     /locus_tag="IXR40_000434"
     CDS             31093..31581
                     /locus_tag="IXR40_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HAQ4360309.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            31632..32504
                     /locus_tag="IXR40_000435"
     CDS             31632..32504
                     /locus_tag="IXR40_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HAQ4360310.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            32680..33042
                     /locus_tag="IXR40_000436"
     CDS             32680..33042
                     /locus_tag="IXR40_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAQ4360311.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            33051..33803
                     /locus_tag="IXR40_000437"
     CDS             33051..33803
                     /locus_tag="IXR40_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4360312.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            33817..35619
                     /locus_tag="IXR40_000438"
     CDS             33817..35619
                     /locus_tag="IXR40_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4360313.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            35896..36936
                     /locus_tag="IXR40_000439"
     CDS             35896..36936
                     /locus_tag="IXR40_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HAQ4360314.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(36988..39132)
                     /locus_tag="IXR40_000440"
     CDS             complement(36988..39132)
                     /locus_tag="IXR40_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAQ4360315.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(39489..40862)
                     /locus_tag="IXR40_000441"
     CDS             complement(39489..40862)
                     /locus_tag="IXR40_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4360316.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            complement(40862..41257)
                     /gene="rbsD"
                     /locus_tag="IXR40_000442"
     CDS             complement(40862..41257)
                     /gene="rbsD"
                     /locus_tag="IXR40_000442"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002829567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HAQ4360317.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            complement(41285..42202)
                     /gene="rbsK"
                     /locus_tag="IXR40_000443"
     CDS             complement(41285..42202)
                     /gene="rbsK"
                     /locus_tag="IXR40_000443"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HAQ4360318.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            complement(42310..43323)
                     /locus_tag="IXR40_000444"
     CDS             complement(42310..43323)
                     /locus_tag="IXR40_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAQ4360319.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            complement(43404..44003)
                     /locus_tag="IXR40_000445"
     CDS             complement(43404..44003)
                     /locus_tag="IXR40_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAQ4360320.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKEIVNNGTLSPHTAASILTNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTDN
                     MLTITKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            44189..44890
                     /locus_tag="IXR40_000446"
     CDS             44189..44890
                     /locus_tag="IXR40_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4360321.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            44900..47611
                     /locus_tag="IXR40_000447"
     CDS             44900..47611
                     /locus_tag="IXR40_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HAQ4360322.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            48062..49690
                     /gene="treC"
                     /locus_tag="IXR40_000448"
     CDS             48062..49690
                     /gene="treC"
                     /locus_tag="IXR40_000448"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HAQ4360323.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(49750..50931)
                     /locus_tag="IXR40_000449"
     CDS             complement(49750..50931)
                     /locus_tag="IXR40_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAQ4360324.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            51183..52706
                     /locus_tag="IXR40_000450"
     CDS             51183..52706
                     /locus_tag="IXR40_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HAQ4360325.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKNGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAGNESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            complement(52775..53503)
                     /locus_tag="IXR40_000451"
     CDS             complement(52775..53503)
                     /locus_tag="IXR40_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4360326.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(53516..54796)
                     /locus_tag="IXR40_000452"
     CDS             complement(53516..54796)
                     /locus_tag="IXR40_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAQ4360327.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            complement(54937..55539)
                     /locus_tag="IXR40_000453"
     CDS             complement(54937..55539)
                     /locus_tag="IXR40_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory regulator AgrB"
                     /protein_id="HAQ4360328.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFVLEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            55784..55990
                     /locus_tag="IXR40_000454"
     CDS             55784..55990
                     /locus_tag="IXR40_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360329.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            56302..57021
                     /locus_tag="IXR40_000455"
     CDS             56302..57021
                     /locus_tag="IXR40_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HAQ4360330.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(57102..57785)
                     /locus_tag="IXR40_000456"
     CDS             complement(57102..57785)
                     /locus_tag="IXR40_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HAQ4360331.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            58004..60190
                     /locus_tag="IXR40_000457"
     CDS             58004..60190
                     /locus_tag="IXR40_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HAQ4360332.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
BASE COUNT        19231 a        10758 c        12216 g        18118 t
ORIGIN      
        1 tttttcatgg cagggccttt tcatttgaaa taggagatcg acgatgaata aaaatatttc
       61 tttaaaagaa agtatcgctg tattgatcgt gttgttggca ctcctaggag tactgatcat
      121 cggattccag ctctcgccac atatcccgat ccttgcagct ttcatgtgtt tgttgtttta
      181 tggcagattt aaaaagttca catgggatga gatccatgac gggatcatca aaggaatcac
      241 tccagggatc attccaatcc tgatttttct tttgattggt gtcttagttg cttcatggat
      301 tttatctgga accatcccta cgattatggt ttatggattt aaacttgttt ctgtgcgttt
      361 ctttttaccg acagcatttc ttgtttgtgc aattgtcgga gtgactgtcg gcagttcatt
      421 tacaacgatt tcgacgattg gaattgcttt tttggggatc ggtcatttac ttggattcaa
      481 tgatgcaatg actacaggcg cagtcgtttc cggtgccttt ttagggaata actgctcgcc
      541 tttatcagat acgaccaact tggcagcggg tattggagga gttaatctat tcgaacatat
      601 cgctggtatg cgttatacgg atttcccagc attcgtcctt tcgttgattt tttatacgat
      661 attaggacat aacagtcatt cagccgatct agctagtatc aatgaaatga tccaaaacat
      721 gaaagcgagc ttttggatct ctccttggac attgattcca ctagttattt tatttggggg
      781 ggcaatcaaa aaaattccgg ctatccctac attactagcg ggatcgacag ctgctctcgt
      841 tctttctttt atccatgaga aaagtttgac ggtcggaaaa gcagcagaca tcttgatgaa
      901 tggttatgtc gcaaatacac ctgatccaaa gctagatgaa ctgctttctc gaggcgggat
      961 catgagtatg ttaggttctg ctagtttgat tttacttgca ttggcattag gtgggttact
     1021 gatcaaatat ctgatcgttg ataccatcgt tcaagaatta aaagaaaaga tggaccgacc
     1081 ttctcgttta gtcgggttta ctgccttgag ctgtatcgga atcaatctga tcgttggaga
     1141 acagtatctg tccatcattc ttccaggaga aacattcaag cgttcttttg atgacgttgg
     1201 cttatcaaaa acctatttga cacgaacact agcggattca ggtgcgaccg tcaattctct
     1261 cgtaccgtgg ggagtcagcg gcacattcat tatgggaacg atgaaagtta gcgcgttgca
     1321 ttacttgcca ttcgcctttt tctcgattct tgcacctgtc tttacaatat taggcggttt
     1381 tttattgaat cgtcgacgtg taaaaaattg aaggaaggaa aaaagaggct gggacagaag
     1441 cgtttaactc caagaaataa gaagaaactc aagaaaattg ctttttaaat ttttgtgaat
     1501 ttcagcttat ttccgaagga gttgcttctg cttccgccgt ttatacgtgt ttagagcgtg
     1561 agacaaaagt gttctttact tttgtcccac gctctttttt acagataaac aatgtgttag
     1621 aagtagtatc ttcttttaca taaaaagctg accataggat aaatggtcag cgtatttagt
     1681 gagtcagcta tttagtatgg gttttctaaa ggaacgactg tctctctttt gatcaagcga
     1741 tgagggatga ccaaacgtac gccactgctc aattcttcat ggatcaattc gcgcagcttt
     1801 tgcatagcga cacgtcctaa ttcggagata tcgatatcga tacttgtaag gtaagggtgt
     1861 gttaatgttg agaagatcga gttgttgaag ctaatgacgg agagtgtctc tggaatgaca
     1921 tagccataca tttgcgccaa ctgcatcgtg cgaagggcga agatatcgtc aatgaccacc
     1981 aatgctgtgg cttcgttttc tttcaacgtt ttctcaaagg acagataatc ctccggatgc
     2041 tctagtacta cactggataa cgcaggaaga ccagccatca tcattgcttt ttgataaccg
     2101 aaatatcgtt cgaaatacaa actttcatga gtcgtgtttg tcacaaacag gatattctta
     2161 tgtccattct ggatcaaaaa ttctgttgct tgtttaccta gaagctggtt atcattatct
     2221 acataaacga tttcgttctc atgatgataa ggctgtccga tcaaagtgaa agggatgtgg
     2281 ttttggtata aataatcaat gacagtatct tgactatctg aatacactag aataaaacca
     2341 tctacttgtt tttgtaaatg catacgctgg acgttctcta acagcaattc aaaattttta
     2401 gcagtagcga ttgctgtagt catatcataa ttccgcgctt cttcgttgat tgcttccatg
     2461 atctcaagat aaaatgggtt accgatccgc tcttttgaat caagaggggg taagattacg
     2521 ccgatggcac tggaaatgcg ttttcctaga ttgcgggcag tcatgttagg aacataacct
     2581 agttcatcca taatttttcg gactttcttc tttgttgtct cggaaatact aggatgatcg
     2641 ttgatgacac gagagacggt cgaggtggca acaccggctt ttttcgccac atcttttacg
     2701 gtaatagcca tgataaaaac acctttctct tgttattgtg cagagaaccg ataaatcgtc
     2761 tgactgatcc gttcttgacc aggatggagg ttgatcgatc caaatttggg gaaatgaacg
     2821 atatcaggga tttcttgcgg ttcgattgct aatccgtagt ttgaatgcat ctgttttcca
     2881 ttgacagaga aatcagcttc gaatccagtc gtagaaaata ataccatact tttattagaa
     2941 gttgctatag tcatttggcg accagaatgc ttctcgaata attgtaagga agttttggaa
     3001 agcctaggat gatgcaaaag aaatacatca tctagtccat ctggataaca tgcaaggatc
     3061 tcttgcagtg ttggggattt tctaaagtcg attggcagtt tttctttttt tgtccaattt
     3121 ccagtaggca gtttttcttg atctaattca agcacaccat ctaaaaagac cgttaactga
     3181 tgttcataga tgtctcttgt tccatttcct gaaaggttga agtaggcatg gttggtcgga
     3241 ttgcagatgg tttcaacaag gctactagca gaggttgtca tctctaattc gttttttgtt
     3301 aaacggtaag tgatcgtagc agtgattggt cctggatagg tagaaaattc atcttttaag
     3361 taaaagacca cacctattga tgatggagtt ttgaaaactt ctacttccca aaattggaaa
     3421 gaccagcctt tcgtgccacc gtggatatgg tgtgatccgc agtttttctc caatctatgc
     3481 tcaccccaag aagcatcccg gatccttccg gctacaggtc cgacagttgc tccaaaaaag
     3541 cttttgtctg ttagaacatc ttcgaaacga tcgtaagaca ataaaacatt ttctgatttt
     3601 ccttctttgt ctggtgcgaa gatttggtgc aggcgggcac cgtaattgag aagaacgact
     3661 tctaagtagt cgttcttcaa tgtgattttc tttatttcag tctctggaac tggtacgacg
     3721 gagatctctg gattatccat ggtcatgcca cttttctttc aagtaatcga tcgtaagaaa
     3781 agtcgtatca gggacaagcg ggatctcctc tccaaggtct tcagcacgtc ccacgccaat
     3841 tggttgagcg ccacttgaga ggatggcttg gataccggct tgcgcgtctt cgatcccgat
     3901 acattcttct gcttttagtc cgacagcttt tgctgcaagg aggaagatat ctggcgcagg
     3961 ttttccgttt gttgcttctg ccgggtcggc aatagcatca aagtaaggtg taagacccat
     4021 tttttcaagt aggaatggcc cgtttttact tgcagaagca agagcaatct tgattttttc
     4081 ttcttttaaa gaatccagta aaggcacgac cccggggaag acatcttttg gttcgatcgt
     4141 ctggatcatc tctaaataat aatcgttttt tcttttcgct aattctgcaa attcttcctt
     4201 tgaaaaagag tgttcttttc cgccataagc taaaagcaaa gagagtgagt cttctcggct
     4261 gacgcctttt agctgttcgt tgaatgtgtg gtcgatcgta atgccgattt cctgaccaag
     4321 ctttcgccaa gcacgataat ggaattcagc agtatcggta atgacaccgt ctaaatcaaa
     4381 caatacccct ttaaacattt gcttcctcct ttcttagcgt tatttctaga cgatccgcta
     4441 aagaataaga ctgttcatag acgtaaattt ctagaggaga accttctaat aactcgaaag
     4501 taacttgttc atctgtgact gagatgaaca ataaacgtcc gcgataattg atatggaaag
     4561 aataagcttt ccaagttttt ggcagaaatg gtgcgaatct caactgatca tgggcagttt
     4621 tcatttgagc aaatccttgg acaatcgaca accagctacc agtcatggaa gtgatgtgca
     4681 agccgtcttc tgtgtcgtta ttgtaattat ccaaatccaa gcgagctgtt cgctggtaca
     4741 tttctacagc tttgctttcc attcctaatt ctgctgctaa aatcgaatgg atacttggcg
     4801 aaagggaaga ctcatggaca gtcattggtt catagaaatc aaagtttttt tgcttttctt
     4861 cttttgtaaa agtatcattg aagaaataaa tcccctgtag tacatctgcc tgcttgatga
     4921 agcaagatct aaggattttg tcccaagacc aatgctgatt cagaggaaga tcgcttgtgg
     4981 gaatatcgga tacaggcatg agatctttat ctaagaatgt gtcatgctgg acaaagattc
     5041 ctaattcttc gtcaactggg aagtacatgt tctctgcgat atctttccat ttggctagtt
     5101 cttcttcgct gatagtgata gcagcttctt tttgataagt taaataattt tctcgcgtgt
     5161 aacgcaagac ccaagctgcg atcgtatttg tataccaatt gttattgata ttgttctcat
     5221 attcgtttgg gccggtcaca ccgtggatca tgtatttatt tgctcgtttt gaaaaatgga
     5281 cacggtctgc ccagaagcgt gcgatttctg ctaaaacttc cagtccttca tttttcaaat
     5341 attccgtatc gccggtgtaa ttcgtataat tgtagattgc ataggcaatc gcgccatttc
     5401 ggtgaatctc ctcgaatgtg atttcccact cgttatggca ttcgacacca gtgaaggtga
     5461 ccataggata aagcgcgcct tttaatcctt gttgctgagc gttgtggatt gcttgcggca
     5521 gttgattatg ccgatatttc agcagattct tagttacttc aggtttggct aaagcaagat
     5581 aaagagggac agcatacgct tctgtatccc agtaagtggc tccgccgtat ttttctcctg
     5641 tgaatccttt ggggccgata ttcaatcgtt catcttcgcc gtagtaagta gagaatagtt
     5701 ggaacaaatt gaatcgaata ccttgttgtg cttcttcgtc tccttcgatg accacatcgg
     5761 caagcttcca tcgttctgcc caagccgctg tttgctcttc ttttgcttgg atataattgt
     5821 ttgtctggtt cgttaattct gagacagctt tttctgcttg ctgcgcttct ggaatatctc
     5881 tactagtaag aacgataatt tctttttcca ctgaccatgt ctcaccttga gataattctg
     5941 cagacaagca accatgtaat gctaaagtat cttcgtgata gtcagggatg actgattttc
     6001 cattaacgaa atggcgcatt gctgcagtaa cagtaaattg ttcaatccca aagttgtttg
     6061 gaatagtttt agtcgtcaaa tagccgattt cttctatagt tccacgatca atctcattcc
     6121 aaaaatgttc atcatagttg ctgtcttcgt tttgaacatt tccatccaat tttgatacga
     6181 gtttgactgt tccgctacct tcaagcattt ctatagttaa atagatataa gctgattctt
     6241 ttttgacaat gctcagaaaa cgttcgaagg aaatgcgtac tttattagta gaagtagtga
     6301 ttgtgaatgt acgagataat acaccatttt tcatatctaa ttcccagtaa aagtcttctg
     6361 gttccaaaga agccaagtcg atcagctgat cgttgatcga aatatctatc gcgataaagt
     6421 tcaaggcgtt gatcactttt ccaaagtatt ctggataacc atttttccac cagccgacac
     6481 gtgtcttatc gggataccag acacccgaca aataagtacc ttgatggtgg tcccctgagt
     6541 aagtttcttc aaagttcccg cgcatcccca tataaccgtt tccaatactt gttaaagatt
     6601 cttgcagtcg aagatttttt ttatctaatt gtgtcgtgct gattttccat ggatcaatag
     6661 caaatagtcg tttgatctgt ttcatttttc tcctcctaat gagctgtttt atacgttcat
     6721 aataaacgca accgattgca caagtcaata gacaaaagaa aatatttcat agaaaaaagc
     6781 ttaaaaaaat aaatttttag gagaaaatta tagaagggaa cacacgtatt ataggtttta
     6841 tagaatggta tagacagaaa aataaaaaat aaagcattta caaaaaagaa aacgcacgct
     6901 ataatacgtt taacgaaacc gattgcgtaa aggagctaaa cggaatgaaa aagatattta
     6961 gttttgagtt ttggcaaaaa tttggaaagg ctttaatggt tgtggtagca gttatgccgg
     7021 cagctgggtt gatgatcagt atagggaaat caattccctt gatcaatcct gattggacgc
     7081 cgcttgtcac aacgggcgga gtaattgaaa atattggttg ggcaattatt ggtaatcttc
     7141 atattttatt tgctttagca ataggaggaa gttgggcaaa agaaagagca ggcggagcat
     7201 ttgcagctgg gatctcattt attttaatca atcggatcac tggggctatc tttggtgtca
     7261 caagtgacat gcttgcgaat gaagatgcat ttacccacac tctgttcggt acgaagatca
     7321 tggttaaagg attttttaca agtgtattgg aagcaccagc tttgaatatg ggagtattcg
     7381 tagggatcat cgctggattt gtcggggcaa tggcttataa taagtactat aattatagaa
     7441 aattgccgga tgctttgtca tttttcaatg gaaagcgctt tgttccgttt gttgttatct
     7501 tatggtcaac aatcgtggca ttgattcttg ctgtggtgtg gccaaacgta caggctggaa
     7561 tcaataattt tggtttatgg attgcagaat cacaagaaag cgcaccgatt ctagcaccgt
     7621 ttttatttgg aacattagaa cgtttactat tgccatttgg attgcatcat atgctgacga
     7681 ttcctatcaa ctatacacag cttggcggat cgtatgagat tttatcaggc gcacaggcgg
     7741 ggacacaagt atttgggcaa gatccgttat ggttggcttg ggccactgat ttagtgaatc
     7801 ttaaaggtgc aggggatatg tcgcaatatg agtttgtgtt gcataactgg acgccggctc
     7861 gtttcaaagt aggacaaatg attggttctt caggtatctt gatgggaatg gcttttgcga
     7921 tgtatcgtaa tgtcgatcct gataagaaag caagatataa atcaatgtat ttttcagcag
     7981 cgttggctgt ctttctaaca ggtgtaacag aaccattgga gttcatgttt atgtttgctg
     8041 ctgtgccatt atatgtcatt tattcagtga tccaaggggc tgcatttgcg atggcagata
     8101 tcttgccatt gcgggtccat tcatttggga atatcgaatt gctgactcgg acaccgttag
     8161 ctatcaaagc gggtctaggt ggagatctta tcaacttcgt gttgtgtgtg atcgcttttg
     8221 gtgttgttac gtatttctta gcaaatttct tgatcaaaaa attcaacttt gctacaccgg
     8281 gacgtaacgg aaattacgac aatgacagtg aagaaaccgt tgtatctaac agcggaacag
     8341 gaacagcaga tcagcaagtg gtccagatca ttcatttgct gggaggaaaa gaaaatatca
     8401 aagatgtcga tgcttgtatg actcggttac gcgtaagtgt aaatgatcga gaaaaagtag
     8461 ggactgaaga agcctggaaa cgagcagggg cgatgggatt gatcgtcaaa gacaatggag
     8521 tccaagcagt ttatggacca aaagcagatg tcttgaaatc agatatcgaa gatctgctgc
     8581 aatcaggagc agagattcca gagccagaaa tggtttctac aggaaatgga caagcaggta
     8641 gtaagcaata cttaggtata gaacaagaac tagtttccgc agcttctgga gaagtgattc
     8701 ctttatctga agtaaaagat ccggtattct cacaaaaaat gatgggtgac ggctttgctg
     8761 ttattccaac atcaagagaa gttgttgcgc cgatcgctgg aaaagtgaca agtattttcc
     8821 ctagcaaaca tgcaattggg ctggaaacga aagatggtat cgaagttttg atccatatgg
     8881 gaatcgatac agtccaaatg aatcagccag cttttgagat tgctgtcaaa gaaggccaag
     8941 aagtaggaac aggaacgaaa ttagctgaga tggatcttga tgtgatccaa aacgaagaaa
     9001 aagatccaac gatcatgatc gtatttacaa acgataaagt agaagaagta gtgatcaagc
     9061 aattaggtac agtgacagct ggtaaagtga tcggctccat taaaatgtaa ggagaggttg
     9121 tgaaaaagct gtcctgcatc aagtcataag aacagccaaa caaaaatagc tcctcctatt
     9181 tttcgtttgg ttgggcttat taccgagaag cagcagtttg aatactgttt agtggagagg
     9241 tcgtgaaaaa gctgccctgc accaagtgat aaaaacagcc aaacaaaaaa tagctcctgg
     9301 tccattgagc ttattactga ggagttagca ggagaacact atttgctgga gaggttgtga
     9361 caaaaatttt gtcacaaccc ttttgtttcg aaatgaagac aaggagaaaa ccaatgaaat
     9421 tcatgacact caacacgcat agctggcttg agccagaacc agagaaaaaa ttgcaagaat
     9481 tagcagataa gatcctgtta gaagattatg aagtgattgc tttacaagaa atcaaccaat
     9541 tactggaatc tgaagaagta gaacctgcga agctaatgaa gttctgtccg gtaaagaatc
     9601 aagtacctat ccgtaaagat aattttgcct accgtttagt tcagctttta aaggaacacg
     9661 gaaaagagta tttttggagt tgggaaatga gccacatcgg ttatgataaa tatgaagaag
     9721 gaaatgcact gcttacgaaa aaaacattgg aaagtcaggt ccttaccgtc tcccaatttc
     9781 aaaagaaaga agattatcag acacgcaaga tcttgattgg gaaaacaaag atagatgatc
     9841 aggacatttt tgtctcgagc tgccactttt cttggtggac agataaaaaa agtggctttt
     9901 attttgagtg gaaaaacttg gaaaactact ttttggaaac tcgcgtacca ctttttttcc
     9961 taggtgattt caataatcca gtagactctc aaggttatta tactgtaaga gaaagttgcc
    10021 ttcttcttca agattcgtat gttgtcgcga atgaaaaagg aaaagcagct actgtggaaa
    10081 agaaaataga tggttgggaa caaaatacag aaaaattgcg tatagatttt attttcgtcc
    10141 ctgaaggaat gcaggttaaa aaatatcaac ggatttttga tgggatcgat agtccaatca
    10201 tcagtgatca ctacggggtg gaaatcgaat tagatgtgaa cgaataaaaa atataacata
    10261 taacataaaa aaactgatta aaataaaact ctccaaacga ttataccgtt tggagagttt
    10321 tttgatcgga tgtatttatc ccttttgcct aagcacgtaa aagcttgtat ctatgataaa
    10381 taaataaaca tagcaaggta aaccagccaa tcaaagtaag agaaagaatg aaatagaaat
    10441 agattggcgt ttgataatga agcgtgagct cgttgattcc tttttgctgc ttcacgattg
    10501 gggtcccgat atctgttact tcataatcag tcaatgtttt tccattttgc tgtagcacag
    10561 tccgatcgta gacgataaca gggatatgaa cagttttgtc cccagtgttt ttccacttga
    10621 ttgtcaaaag accgcctgga tgtgttttta taaaagttgt ttcgttttct agtatttctt
    10681 cgttataccg gtcgtattta ttgtcttttg tctccttata gattggcaga tagtcaggtg
    10741 tggttttttg gaaaacgaac aagctggtag acatatcttt gctgaagaat gttttccttg
    10801 cttcttccgg cgtatcgaat agataagtat gtcgactgac aaatgtttca ttttcccact
    10861 tttccagatg ctggtataag ttctggatcg tctgtgctga aaaaataaga atgccaaata
    10921 tacttaaaag acggaaccac ttttgttcag accactggtt cagtgaaagg gcaaggtaaa
    10981 gtagaagcaa tagcgtaaat ggcacgaaaa atcgaaatgg aaactggatc aaactaataa
    11041 aaggcacatt tttttcgatc aatgtcgtcc atggaatcaa gctagtagaa agaaaaaaga
    11101 aaacaagact tgtgtacaac acgatttttt ggaataaggt gttcttttgt tgaaagaaaa
    11161 taaaaagcaa aaaacctgat aatatcaata taggaaaggc cttagggtaa tggagccaat
    11221 aactgccatc cagatctatc gccttttgac tcatttctct gttaacaaag ggaggaagaa
    11281 tcttattccc actgtaaaca atagctaatc ctgcccaaat atttgctgtc agaacaaaat
    11341 aaagcaagac cgacttaatc agttgaagca gtgcttttcc tttttcagtc tggttaaaaa
    11401 agtaataaag ataaaaaggg atatacatca aagctaacat gatcgaagac agtaaatgga
    11461 tctgtgtcat aagtcccact gagacagcga ctttgataac agggaacttt ttatgaagga
    11521 cgaaatcagc aatagggatc atacataaag gataaaaaca agtcccccag ctagtgaatc
    11581 cttggttgat agaccagtat tgaatagaat acgtactcat gaataaaacg gctactggta
    11641 cacttaccca atttcgaaca ttgacatatc tcagtaaaat cagcatagaa aatcctgaaa
    11701 taagataaag aatgaaattt gaaagaatct gataatgaaa ccagctacct gcaagcaaca
    11761 cgatcaatcc ttgtaaataa gcgaaaaatg ggccgtaaac ggcattcacg atcctgccac
    11821 tttgctggaa tccataaagg gaaggaaaat aatggaaatc cccatattta atttgttgcg
    11881 cggcatcata gaaccgattg taatggaatg gggcatcagc acccaaaatt agtttatgtg
    11941 tgaataaatg aggcatgaga aatgccaaag caatgaaaaa aattgctaaa aatgggccat
    12001 attttttcaa ttgtcgaact cctttgcaaa ctttagataa attcatcata tatcctatgc
    12061 gagaggtagg caagaaatta gaaaattcat gaaaatattt atgaatttta caagaaaaac
    12121 ataagtgaaa gttctaagga gagaggatgc gacataagtt ttgttgcatc tccttgtttt
    12181 gaaacagaat ttttcttaat actcgaaaca aagtagcttt ttcatgacct ctcggtaaac
    12241 ggtgttcaat cagctgcttc tcggtaataa gctcactagc ctagaaaata tgagaagcta
    12301 ttttctgact agcgctctta ttactcaaag cataacgcag ttttcacaac ctcttcctta
    12361 aacggtgttc aaaagcttgc atctgcggta ataagcccaa cccaacaaaa aatatgagta
    12421 gctatttttt tgggctgtac ttattacttg atgcaggaca gctttttcac aacctcatcg
    12481 gctttcattt tctatttttt tcctgaaccc atataataaa agaaagaaca aaaaaacttg
    12541 caagggagga cacatgtgaa gcagagtaag caaaaacagt ctcgtcgact tttgtttcgt
    12601 ttgtttttat taatatgtat cgtcgtaggg ttactgatcg ctttatatcc attttatgtg
    12661 gattctttaa atagttttat tgatcaaaaa cgtatcgaac aagtacaaaa acggaccgca
    12721 gctgaaattg aagtgcagcg aaagaaaatg gaggagaaaa accaacgatt aactgaccaa
    12781 ggattcaatc ctggtactga tcctttcaat gaaaagaaca gaaatgaaag tacaacatcc
    12841 agccaattag aggaatggct gatcggaagt atcaatatac ctaagatcca attaaatatt
    12901 tcactttatg atcggctcaa tggtaggatc cttgaaaatg gagcaggcgt cttgcaagga
    12961 acctctttcc cgcttggtgg aaattcgacg cattcagtga tctctgctca cagcggttta
    13021 cctaatcgac ggttatttac cgaattagat cgtttagaaa acggagacac gtttattttg
    13081 actgttttgg gggagaaatt ggcttatcaa gttaaaaata tacaagtggt actgccagat
    13141 gacacgtctg ttctaacgat ttcagaagga gaagacttag ttaccttgct tacatgtacg
    13201 ccgtatatga tcaacacgca tcgtttgcta gtgacaggac atcggattcc ttataacgaa
    13261 tcggtaaaaa aagaagaagg aaaaggaaat caggaaagaa ccatgcggca atggtttatt
    13321 cttgcaggaa cgataatagc tgtagtcata ctgttagtgt ttatcggacg actaatctat
    13381 cagtatagat taagtaaaaa agtgcttgat ttttcattta ttattagtga ttcgtcaggg
    13441 aaaccggtaa atggtagttc attcattttg aaacataaga aaaaaacact tactagaaat
    13501 ggtgtgccgt tttcagtaca aagcgaccat catgggaaag tcaagctgga tcaattgcct
    13561 ggtggaactt atcgaatcgt ttcagctgat gatcctaaag ttgctgtttc ttttggtatt
    13621 agaaaagtaa aacaagagaa gatatacttt tttgaggggc gaaaacttgt aaaagagctt
    13681 caaaaaaatg gtttttattt taaaatcaat gaataagtaa ggagagaaaa aatgatccgc
    13741 acaacaacaa aattgtctgc caaagaactg gaatctgttc tatcgatttg gctgcatgct
    13801 aacttggatt ctcatgaatt cattccatca acttattggg agaatcaagt agaatctgtt
    13861 aggaaagctt taccagatgc agtgatttac ttagcagaaa tagatcaaga aattattggt
    13921 tttgctgggg tgattgatca gtttatcgca ggaatctttg tgaaaaggga ataccggcaa
    13981 caaagaatcg gtacgcaact aatgaaaaaa ataaaagaaa ccaataaaac actgactttg
    14041 acagtctatc aaaaaaatca atcagctatt catttctatc tttcacaagg ttttacaatt
    14101 caaacacagc aaaaagatga agcagtaaat gaggaggaac ttgtgatgaa atggaatcaa
    14161 aacgctgatt tttgatgaac agaataacga aataatgctc ccagcctaat tttttgctgg
    14221 gagcattatt tcattttgaa gtcactaatt taactgtgtg aatatgcagt tgttacaatc
    14281 tttgataaac ggtgttcaat cagctgaccc tcggtattag ctcaaaaaac ggcaaaatat
    14341 gaggaactat ttttccattt gtttctctaa tactcaggtc aaaacgctga tttcacaacc
    14401 tcttgataaa cggtgttcaa acggctgctt ctcggtaata agcccactag cctagaaaat
    14461 atgaaaagct attttctaac tagcgttctt attactcaaa gcataacgct gatttcacaa
    14521 cctcttgata aacggtgttc aatcagctga ccctcggtat tagctcaaaa aacggcaaaa
    14581 catgaggaac tatttttccg tttctttctc taatactcag gtcagaacgc tgatttcaca
    14641 acctctcttt cacaacctta ttttactcgt ttataatttt catcgaagta ttttccgcta
    14701 cggatatcat ctggcattcc atcgtatggt tcttcgctaa taacatcttc attgtctata
    14761 cctgcatcac ccatataagt gatcgtagca aattcaggaa caagtaattt tggataagtt
    14821 tcatattttt cacgagctgc ttccatttct gcgatatgtt cgttttggaa agtaacagtg
    14881 atttctggat gttcttcaac ccatttaggg aaaaagatca ttccgtgaag tttcttttca
    14941 tttggcataa agtccaatgc cacgtctgtc cctgttggct ctgtccaagt gattttgaat
    15001 acgccgtccg tcaatttaac gatatcagct tcttggtctt ttacccaacg gcctttgacc
    15061 attccgccat ggatacggta atcaacagta tggtcatttt tggcatacca ttcatattcc
    15121 caaccattgt catacgtata gataaagtga gttccaataa aatcttccaa ttctttaaat
    15181 tctttcatgt ttaagcatct ccttataaat taaaacatgt aataaactac atgttttcga
    15241 ttactcattt atgatagaat ggatttaaag atttgtcaag gagggaaaac tgatggcaag
    15301 aaaaaataca cttcgatata ttttgttagg gttattaagt aagaagaaga tgacaggata
    15361 tgaattgaat caatcgttca aaaatgaaat aggagaattt tggcaagcaa aacatagtca
    15421 gatttatcct gaacttgcaa aaatggaaga gcaaggaatc attcagcatc aagtagagat
    15481 cacaggtgaa aaattggaaa agaaagttta tgaattaaca gaagaaggga aggaacaatt
    15541 ggcagagtgg attcatacac ccaccaatga actaccggtt aatcgagacg aatttgttct
    15601 gaaattgtat ttcgtcaaag acgtgaatga tccggcatta gtagaaatta ttcagcagca
    15661 gcgtgacctt catgaagaaa aacgacttca tctattagag cgaaaaaaaa cgatctttcc
    15721 tactgaaaaa gaaaaacatg aaaattacgg acactacctg attttagcgc atgcgatcaa
    15781 tcgggaaaca gaatatgcaa attggctaac agatgtatta gaagaaagta accgaaaaaa
    15841 ataaaaaaat atccgaacag tgatggagaa ttcctttcta tatgaaagaa acgcagatca
    15901 ccgttcggat attcttatgt tcaaacaggc cttttttcaa gtatttatgt agcatctact
    15961 tattaaaaag cttggtactt aggagattag tggcgtttag agttctttta acaactgttc
    16021 gtagtcagct ttttcatcga caggaaggag cttgtaagtt aattcgtctg tctcgttgtc
    16081 atgaatgatg tacatcttag cattctcttc tttgaagtta ccgatttgta aaatcgtata
    16141 gcgttcgtcg atcaattcga tatctttgat tgcttttgaa aaaactttac ggacatggtg
    16201 cattttcttt tggcggattt ctgccttttc tgcagctttt gacaaagtaa atccgtcatc
    16261 taaatatttt ttgatcagtt ctacttttat gactgtaggt aaacgatatt ttctaggaca
    16321 attcgcatca gcttcgatcg aacgaatgaa tcccttttgt tcccaatacc ttaattgacg
    16381 tggagacaca cctacgatat cacttaattc actgatgcca acaaccaatt gatcattttc
    16441 caacaaacgt ttaagggaag ccccaaccat ttttgtcact ccttttgtcc tcttgcttcc
    16501 cttaattata tccgtattaa cttatgtgtc aagtaggttg acaaatagcg aatttaggac
    16561 taaagtattc tagtagtttc agaaaaaatt cagaaagaag gagaaatatg agtaacaacc
    16621 aacccgtaga tatttacgga aaaccatata atcggacact tttagttgtt gtcttattaa
    16681 ttggtacatt ttgtaccgtt ttgaatcaga ccttattgac gacagctttt cctacattga
    16741 tgaaagcttt cgatatttca gcgtctgatg tgcaatggtt aacgactggt ttcttgctag
    16801 tcaacgggat catgatccca ataacagcat ggctgatcaa taaattcagt tcaagaaatt
    16861 tatatctttc tgccatgacg atctttttga tcggaacgat tacttgcttt acagcaccta
    16921 attttagtac attactaatc ggtcgtttga tccaagcttg cggtgtggga gtatcgatgc
    16981 cattattgca aaatatcatg ctatctattt tcccgccaga aaaaagagga tcagcaatgg
    17041 ggatgtcagg gatcgttatt ggacttgctc ctgctttagg ccctacatta tctggttata
    17101 tcattgataa ctaccattgg cgtgacttgt ttggtatggt actgccaatc gttgttcttg
    17161 tcttggtttt agcattcttc ctaatgaaaa gtgttattcc attgtcaaat cctagcattg
    17221 atattttatc cgctatttta tcaacgattg gattcggtag tttactttac ggattttcta
    17281 gtgtaggaga tgacggctgg ggaagcttga aagtaattgg tttcttagtt gttggtgtga
    17341 ttttcatcgc cttgttctca tggcgtcaat tacatttgga acatccattc ttggaacttc
    17401 gtgtattcaa atcatctaca ttcacgattg cagctgtttt agctggtgta acaaatatgg
    17461 cgatggtagg ggcagaaatg gtcgtaccat tgtatattca aaatattcgt ggagaatcag
    17521 cattccattc tggcttgatg ttgttgccgg gtgcattgat catgggggct atgatgcctg
    17581 tgacgggtgc gattttcgat aaatacggcg cgaaacgttt agccatcaca gggatgttca
    17641 ttttgacagc ggcaactgca ccatttgctt tcttgacaaa aacgactcca gttttatata
    17701 tcgtgatcct ttatgcgatc cgtatgtttg ggatctccat ggtcatgatg ccggtaacga
    17761 cttctggtat gaatgcattg ccaaataact tgatcagtca tgggacagcg gtaaataata
    17821 cattccgtca aatcgcaagc tcgattggta cagctatttt gatcagtgtg ttgacgaatg
    17881 tgacaaaagc aaatatccca agcaaatctg tattggataa tacgccatta gcttataaag
    17941 atcaggcaat caatgccaca ctgtcaggtt accatgccgc gtttatcgta gcgatcatct
    18001 ttgggattct tggctttatt attgcctttt tattgaagaa aaaagaacct gttctaatga
    18061 aagcggggga taatgcatga ttattggagt tttgattgtc agcttgcttg cttttgcttt
    18121 aacgaacgtg ttcgctaaaa aaacatggca aaccttttta tctttgattt tcggactaat
    18181 cttcgtcgct tcactaagtt tgatcgtcgc taatttgtcc aatcactttg gaatggaaaa
    18241 agtaacggaa acaaaaacag aaaaaattgt ttccagtgct gattcccaag gagcagatat
    18301 gcttttgtat aaagctttag ggaatggaaa agaaaaagtg tatctttacc gaacaaatga
    18361 aaaacaagaa aaaccaaaag caactggtac ggataacgaa acaaataaag tagaaaagac
    18421 agacggcgat gctgaaaaag tgacgaaaac tacttattgg gaatacaaaa acgacatgta
    18481 taaattctgg ttcaatattg ctgataacaa tcacgaatat gacagccgag tgaatacatt
    18541 caaaatccca gagacatggg tagaattaag tacggaccaa gcagccaagt tagctgaatt
    18601 agtgaagaaa cagcaaagta cgatggaaag tgaagcaaaa gcttatgttc aagacggtat
    18661 ggtaaaagca atgactgaaa atccaaaaat gagcaaagca gagcaagaac aacgtacgaa
    18721 agccttagct gctgaattcc aacaacaagc attcgcaaaa ttagtgaaag aagcaaaagg
    18781 cgaataatat tttgaacacc atgtaggagg ttgtgaaaaa gctgctctgc atcaagcagt
    18841 aagaacaatc agataaaaat agcactccat atttttcatc tgattgggct tagtgccgta
    18901 gatgcaagct tttgaacacc gtttaaggaa gaggttgtga gcctgccgtt taactctgag
    18961 tcacaaggag caatttcaaa aaacagcttc tcatgtttgt tgactattgt gacttgtgac
    19021 cgaggagttg gcaggagaac accgtttatt cgaaaaaagg aactgcgaca agacttttgt
    19081 cacagttcct tctttttttt gctatgctat actagatgta aaaaatagga gaaataaaat
    19141 gagggaaatt tattcttttg aatcaaaaat ctatgcttcc gaagtcggca agggcggggc
    19201 atatattatt tttccgtatg atataagaaa agaattcggt gctggaagag ttaaagtcca
    19261 agcaactttt gacaatgtgc cgtatgaagg cagtatcgtg aatatgggcg tgaaaaatcc
    19321 agatggttca gtctgctaca tccttggact acgaaaagat attcgtaaaa acatcggaaa
    19381 agaaatcggt gatattgtag cagttacagt gaagcaaaaa taaaagaggt tgtgacaaaa
    19441 gacgtgtcac aacctcttga taaacggtgt tcaaaagcca gtttctcggt agtaagtcaa
    19501 atttatgcaa aaatgtggaa acccatgttt acaaaatttt tcttactact cgaaacgaag
    19561 cggctttatc acaacctctt gataaacggc gttcaatcag ctgtccctcg gtattagctc
    19621 aaaaacggca aaatatgaga agctattttt ccattttttt ctctcatact caggtcataa
    19681 cgctgatttc acaacctctt ctttcataat ggtttttcac catctttata ataaactggt
    19741 tatttgatat ggaaatctat tttttccaac caatctaaaa tcttgtaacc taactcttct
    19801 gacatcggaa aagaggcgtt gatttgtgca ttggagatat ggtcaacatg gataccggaa
    19861 gtgatcgtac aacttcccgg aacggcagtt ttgatgatca cagctatttt ttcggctaag
    19921 acatcgtctt tatggaaccg accatcgtgg ctagggaaac gtacagtttg catctctgta
    19981 tcacgagaaa atgtagtgac tgttccgata tgtggtgtat ctccgcctgt taaagtgatc
    20041 aataagtctt taccgattac tttaacagca gcttggatcg tgaaacctag tttggttact
    20101 tcaactatcg tttctttttc catattaatc accctgccaa cgttttgaat gctcatttac
    20161 aatttcaaat tgatccaaaa gtttcattgt atggtgatta acaagatctt ggatcgtttg
    20221 aggctgatta taaaaagcag gaattggtgg tatgatttgc acacctagtc gtgctaattt
    20281 agtcaagttt tccaagtgaa tggcatttaa tggcgtttca cgaggaacaa tgactaactt
    20341 tcgttgctcc ttcattgtta catcagcagc acgtgcaatc aggttgtcgc ctaaaccaac
    20401 agagatacct gcgactgttt tcatacttgc cggtacgatg atcattccat cggtcaaaaa
    20461 tgatccgctg gcgacagcag cacctaaatc tttgtttgaa taatggtaat caaacaggct
    20521 ttcgaattca gttagtgata agtcggattc cagctttaag ttctgttttg cccatggact
    20581 gatgattccg tgtgtttcta tcatcggata ttcttttagt ttcttcacta ggttgatggc
    20641 ataaatggtg cctgaagcgc cacttacacc aatcacgatt tttttcttcc gttgtgccaa
    20701 ttgttccatt ttccgcactc ctttttatga tgtcaaaaca gttgcagatc attcattatt
    20761 tcaaatattt ttcccaatct tctacttctt ggaattttgc acgtacaaaa tgttctttca
    20821 tatcgaaagg aactgtaccg tcaaagatag tttttgcact tatcccacgg aaacgaatag
    20881 agccaggatt atattctggt aattctgatg ggtccaatgg atggttcctc attcctggga
    20941 tcacgatgat atctttatct ccttggaaac gagtgttgaa agtccaaact acatcgttca
    21001 tgtcgaaaat atcaacatct tcatcgacta aaatgactgt cttcaattct ttgaaggctg
    21061 ataaagcaag aatagctgct tgacgctgaa taccttcatc cgcttcgttt tctttacgga
    21121 tttgcatgat ggtcatcaat ttaccaccac ctgcaggagg attgtagaca tttactactt
    21181 ttcctggaat agctttatcg accaaggcaa gaatacttgc ttctgtagga ataccggcca
    21241 tagatacgtg ttcttcactg ggaccaatcg ttgtttgcat gattggattg tcttttcggt
    21301 gagtaactgc tttgactttc actacttgta cagctggatt agcatcccca gtatagccag
    21361 gaaattctgg cattgctttt cctgagttcg tgttgatatc ttcttgcatt gtttcatttg
    21421 gcatgatttc tgcttcaatg atgaattcag cacgagcaat acccacttca tcgactgcta
    21481 taccatcaac gatttgaata ggttcgttac gcaaagctcc tgcacaccat agttcattgt
    21541 agccaagtgg agtggtaggt ggttcgaaag tcgtgccaat ggcaattgct ggatctaaac
    21601 caatattgat agtgataggc attggtttat tcaaggcttc gaattgtttt tggaagtgac
    21661 caatgtggcg tccgccaggc atgatgtaca taccgatcgt atctttatct tctagaacca
    21721 tacgatggat cgttacatcg ctcattgttt tttctggatc tgatcctaag actacaccca
    21781 ttgtgatgta tggaccagca tcttcaggag tatttgtagg tgcaggcaaa atgttgcgaa
    21841 tatcgaagtc tgcatcggta gctagatgaa cgacttcttg tgctggagcg tctgctttgt
    21901 ctactttcac aggtttgatt ggattttcta cagcgtcttt caagaaacga ccaagtgttc
    21961 gataatcatg gtgcaaaatt tcacctacac gtttacgact agccattgtt ccgatgttca
    22021 cacgtgtgcc ggggaaacct ttgatattgt tgaaagtcat agctggtcct tcttgagtcg
    22081 gacgttttac tgtaccgcca gcaccgatat aacggtaaac accagataat tctgcttcag
    22141 gatcgatttc aatatctgtt tcgtgatatt gacctggaag tgtttttagt tcttcgatga
    22201 cttttcttaa atcatacggt tgatctgtca tgagagattc ctccttagtt gtctttacct
    22261 atctatagta aaaggtgaaa aagaggaaaa caattcaact tgttcggtaa agtattctac
    22321 aatggaatgg atgcgttttt ttgataatag aataaactat gatatactta tcactaaaag
    22381 aaagcgcata cttagtgttg gaggaaggaa agtgaaaaaa atggaggagt catttcctaa
    22441 agcagtaaaa gtggaaaata tagcgaatat tttgaaagtt acatttgaaa acggagaagt
    22501 aaaatacgtg aaatctcatt ggacagaaga gataaccgat gccttgcaat ttggaaaaaa
    22561 aggaagagga aaaagaaaaa atcttctcgc actttctcgt aatatgtgga ttgggactga
    22621 agtaacgatt gaagcagatg gaacagtatt cataaatgga aaagacaggt atacgccaga
    22681 agagttgtgg tacaaaggaa agaaaagtat accagaatta taaaaaataa ttaaaaaaaa
    22741 cagcgcgaaa caaggaacat attacttcct cgtttcttgc tgttttctac tatttcagcg
    22801 ctcttatgac tcaaatctaa atgtggttgt cacaacctta ttctgcacgc aaagcgatag
    22861 cggcgtcttt tttcgctgcc attcgtgcag gaagatgacc gccaagcatc gtcaatatag
    22921 tagagacgat cactagaata atcgcatgga caggatttag ttgagcaaca ttttttagat
    22981 ccgtcatgtt gtataagatg ctattgatag ggaacgtagc tagccatgca ataaacacac
    23041 ctaatatccc agaagaaata cctaaaatac acgtttctgc gtcaaatacg cgagtgatgt
    23101 cttttttacg tgcacctaaa gcttttagta caccgatttc ttttgtccgt tcaatcacag
    23161 atgtataagt aatgatactg atcatgatca tacttgttac taaagagatc cctgcaaaag
    23221 caataaggac ataagtgata gcatccatca atccgccagt cagttcagtc atcgttccag
    23281 ctaaatcagt ataaatgatt ttatcttcat ctgatttgcc tttattgtaa tcatctagat
    23341 aatccaagat cttttctttg tcttcaaaat tgttcggata aatcatgata cttgaaggca
    23401 agctgtctcc acctaaataa ctaagcaatg tttgtttggc attttcgtca actttttcag
    23461 tagttaagac atttacacca ctgtctcttt gagctttgac gatttctgat tctttgtttt
    23521 cgttgacgat ttgagtcgtt aattgatcgc tataagcgat tcctggagat aagagattca
    23581 ttgtagaaga agatttcacg cgtaggatcc ccgagatctt caattcatca gaagcattct
    23641 gatacatcgc atcataatct gtattaggga taaaattccc agttggaagt tttgtatagt
    23701 aagtattgtt gtttactaat ttgaatgttg taccaacgat atcatcaaaa tcaagttttt
    23761 cgtcttcttt cacatcaaat ccaagattct tcaatgcgtt gatattagta ttattattgc
    23821 cgtctacgat cagcacgaca tctgttgctg aggctggata acttccggca agtaaagaat
    23881 aattgtcttt taaaaagttt tctttgctag tgtcaagctg tgtagggaaa cttgacactc
    23941 ccacacctgt cattgctgac atcgtactag ataaagaaag agattccgta tcaggatttt
    24001 gattcgagaa gctgacaggc tgtactttgc catttacatc acgtaaaaga ttgattcctg
    24061 tagtacgggt aaatccgata ttattactta agttaggatc gatgtctgtt acgtaatcga
    24121 cgtatgtttg atcaatctta ttcgtgtgct gtgctttatc ttcttcgctg acttttgcag
    24181 taatcgtttt gctgtctgga taatccgctt tgcttgcacc caatccggca tcgtcacgag
    24241 tctggttagt cgttacctta gaaatagtaa tcggaaattt cgccatcgtt tcagcttgcg
    24301 tgttatcgat ttgtttttgg aatccagaag aaagggacag aacgatcgcg attccgatga
    24361 tcccaatact ggaagcaaag gaggtcaaga aagtacgtcc tttttttgtt cggatattgt
    24421 tgaaggaaag ctttaacgct gtccaaaaac tcatctttgt tctgcgtaag ttaaattgat
    24481 catcttttgg tcgttcgatg tgaggatggg aatctgttaa gatcttacca tcagaaaatt
    24541 caatgattcg atctgcgtat tgatgggcca gttcaggatt atgtgtgacc atgatcacta
    24601 atttttcttt cgataactct tggatcaatt ccatgatctg gatacttgtt tctgtatcta
    24661 acgctccggt tggttcatcg cacaaaagga tatctgggtc attggctagt gctcgagcga
    24721 tggccactcg ctgcatttgt ccaccagata actgatttgg ctttttatgc atatgatttg
    24781 tcaagccgac tcggtgcaat gcatcttctg cccgttttcg tttttcgtct ttagaaacac
    24841 cacttaatgt catcccaagt tcaacgtttt caataatgcc tagatgacca atcaagttgt
    24901 aactttgaaa aatgaaaccg atagagttgt ttcggtaggc atcccagtca ctgtccttaa
    24961 agtctttagt agactttccg ttgattacca tatcaccgga atcataatta tctagtccac
    25021 caatcacatt cagcatagtc gttttaccag aaccactagg acctaaaatc gctacgaatt
    25081 ctttttgtct gaaagcgaca gacacaccat ccaatgcttt ggtggtggtt tcgccgactt
    25141 tataatattt ttttatatct tttaattgaa gcataatcac ccttctcccg tattgaaata
    25201 ttcggtatac taataagtat atcagaacaa tgatcgtagt atacgaaata aatgttaact
    25261 gaagatgaac tacaagaaaa aatctagaaa tttttcaaaa aacagaggga gatcaatgaa
    25321 tcgtatttta gtagtagaag atgatccgca attacagttg ctttaccgtt ctgtgttgga
    25381 acgagcgggc ttttcagtca tcaccgcatt gaatggagag gatgcgctga aaaaactaga
    25441 agcgacacgt atagaattaa tcattacaga tatcatgatg ccgaaaatgg atggctatga
    25501 cttgctagac tcattacgta gcaccagatt tgacacacct gttctaatga ttacggcaaa
    25561 ggccgatttt gaggataaga aacgcgggtt caaattagga gcagatgatt atatgacaaa
    25621 acccatcgat gtcaatgaga tgatcctacg tgtggaagca ttgcttcgac gttcaaagat
    25681 caattacagc agtagcttga taatcggaca aacaaaatta gagctagatg cttatacagt
    25741 gttacaagat cagcattcgt tgattctgcc tcaaaaagaa tttctgcttc tgtataaatt
    25801 actgtcttat cccaacaaga tcttcactcg ccaacagttg atggatgata tttggggatt
    25861 agatacgaat acagaagaac gaacgatcga tgtacatatc aaacgtttaa ggacccgttt
    25921 tgaaaagacg gaagattttc aaatcatcac agtacgggga ctaggctata aggcggttat
    25981 ttaaagatga aaaaaaagct attttcacaa ttatggatct attttgctag tattgtcttc
    26041 atttcgatct tagtgacact gctgtgtttt ctcggtttta ttttcttatt gtctcgacat
    26101 tctatctcgc ctgctgaatc ggctggaaaa ccaacgttat acccgttatt cgtctttgcg
    26161 gggttcagta tggtcgtggg tacaggaata tcgatttttg ttgggcggcg tatcctgcat
    26221 ccaatcagtg cgctagggac aaatatgagt ctggtagcaa cgggagattt ttcgattcga
    26281 atggatgaac agcagaaagt agcagaagta cagcaactgt ataaagattt caacgttatg
    26341 gtccaagaac tcaatagtat cgagacactg aggaatgact ttgtgtccag tgtatcccat
    26401 gaattcaaaa caccactagc aacaatccaa ggatatgttc aattgttaca agccccaaat
    26461 ctctctgacg aagaacgcca aatattttta tatcggatta tcgaaagtat cacgcagctt
    26521 tcacaattaa cagagaacat cttaaaattg aacaaactgg aaaaccagcg tatccaactg
    26581 gaaaagaaag agtatcgatt agatgaacaa atcagagaag taatcgtttt ttttcagcct
    26641 aaatgggaga aagaacagct agaattggat atcgaacttg ctgcagtaaa ttacacaggc
    26701 aatgaagagt ttttgtacca agtgtggctg aatatcatgg ataacgccat aaagtacaat
    26761 caaatcaatg gacagattca tatcaaacta tttgagacag ccacagagat tgtactggaa
    26821 gtgaccgatt caggtgtagg aatgaatgaa gagaccagag atcgaatgtt tgaaaaattt
    26881 tatcaaggag atacaagtcg tcaaatttct gggaatgggc taggactttc actggttaaa
    26941 aaaattctag aactgcatga tggacgtatt gattatagca gtatcgaagg agtaggaacg
    27001 acagcaatga tacggttaag taaacaatag gaaaaagaat aaaaccccta aaaattctat
    27061 tgaaggtttt taggggtttt tagtcgtttt tttgtgatta gggaaatgtt cttacggttc
    27121 ttttggcata aaaatcgctg ctttcttatt gaactacgag aaatgttaga ggtgtcattg
    27181 aaacaaggac atgatgcaag aaagagagcg aaagtcatgc gtcgctctct ttttttgggt
    27241 ggatagatgg acagaaaatg tagggcttag ttttcttctt gatttaaata ctcccaaaat
    27301 gtatctgaag ccaaagaatg ctcaccgact ttacgagtaa atgcaagata actctctgtt
    27361 gttggagaaa tagggagaat cacagtattt tcttttaata gattcttgac tgttttttcc
    27421 ataacaatag caatccccat gtcatttgca atcatattga tgatcaagtc gattcttgct
    27481 cctttataag agatttttgg ttcaaatcca gcttcgcgac acagatctag tacaggttga
    27541 tacaagttcg tagtggggcc aaggagcaaa aagttctcct ttttcagttc gcttagatcc
    27601 aatttctttt tactagctaa aggatgattt ttaggtagaa ctgctacaaa atcgtctgtt
    27661 tcagtaggca accactcaat cgaacttggt ggggcctgga aacttctagc aaagtggatc
    27721 gtgtcactat gttcattggc gtcattgtaa gttaattcga cactttccac ttctttcaac
    27781 tggactgtaa attcaggatg gcgtttcaaa aactcggtga ttttggaaaa acctttataa
    27841 ttgatcattg tcggtatcgt taagatattt aatgaaagat tgttgtcttt cgtataggtt
    27901 tcaagcactt cttgcatagc atggtattgt tctacgacat tttttacata tgggagcaat
    27961 aagcttccag cttcggtcaa ttcgattttt ctatgggcgc gttcgaataa tttgacgtct
    28021 aattctgttt ctaacgaaag aatctgttta gaaatatttc cttgggtggt gaattgtcga
    28081 tcagcagttt tggtgaaatt cattgtttcg gctaaatcaa gaaaaacttc gaatttatgg
    28141 atatccatca tattcctcct acttattcca ataaagaata ctttaacaca aaaaatgaat
    28201 tggtgtaatc ttctctgtct gttacaatct ttcttgcagc gaaagcaata attacagaaa
    28261 tttttctgat ttttttcgct tcgtagaaaa agagaggagt tttttgatgc caactggagt
    28321 tttgatcaat gtaggttccg ttttgtttgg cggactaatt ggcggattag taggaaataa
    28381 attaagtgaa cattttaaag cacagctgac gatggttttt ggtgtgtgtt cgatggggat
    28441 gggaatctat tccattgcgc cgatgaaaaa tatgccggct gttatttttg ctttagtgat
    28501 aggaacagcg attggtttga ttgttcattt aggtaatggg ataaataagg gggctgcgct
    28561 gatgcaagta cctatttcta aaatcttccc tagtgaaaag cttggtatga cccacgatga
    28621 atttatcagc acattagtga cggtcattgt tctattttgt gcaagtggta cggggatcta
    28681 tggaagttta gattctggga tgacaggaga cagtacgatt ttgatttcta aatctgtcct
    28741 tgattttttc acagcagcta tttttgcgtg taatttaggg tatgtcgttt ctgtgatagc
    28801 aattccccaa ttcattattt tttatatttt gttcttattg gcaaaattta tttatccatt
    28861 gactacacca gacatgatct tagattttaa agcttgcggc ggattcttga tggtcgctac
    28921 cggttttaga atgatcaacg tgaaaatgtt cccagtagct gacatgatac ctgcaatgat
    28981 cgttatcatg ccactgagct ggatgtggac aaattggatt atgccactgt tataataaaa
    29041 atcaaagaga agccattttt tgctgactaa aaaggatcaa atcttttagt cagttttttt
    29101 gtatttgaca aactgatttt gaaactatat tatatgttgt ataatataga ttgaaataaa
    29161 atattacact tgagaataga aggtgacgta atgcacatcc agattccaac tgttcttctt
    29221 gatggtactg tgctagcagc attaagcaag gaagatatgt atgggtatgc cttaacaaaa
    29281 atcgtacaag aaagtctctc tgtcagtgaa tctacactat atccggtttt gagaagattg
    29341 aaaaaagaag gatatcttga gacctatgat gaaccttttg aaggcagaaa ccgtcgatat
    29401 tactcgttga caccaatggg aagtcgtcat ttagaagaaa ttattgatga atggattgtt
    29461 tttcgagatt ctttagaccg gttattggag gagagcacaa atgaatgaat atttgaatga
    29521 agttgtggat catcttcaag aaattcctga agacgatcgt tttgatttga tccagtatta
    29581 tgaggaatat tttttagatt ctggaaaaac attagatcag atcattgatg aatatggtac
    29641 accaaagcag tttgccttaa aattaaaaat cagttacttt tcagaagaag aacaagcaga
    29701 aaacgagtta gtgaaaaatc caaaaagaca aattcgcctg atttggttaa tcattatcgg
    29761 tttatttgct tctcctgtcc tcattccact agcactgggg tttatattgg ttattggggg
    29821 actattggtt gctttactag cgctcatttt tagtatctat gttttatgta tcagtatctt
    29881 aggtgttggc ctattcatga tcatctcagg aatcagtgtg tttggacaat cgattctgag
    29941 tggattattc tttatcggtg tcggtctgtt cgccacagga agcgcagtat ttatttcgcc
    30001 actgttgctg aaaggaacaa aagggctttt ttatgtcatg atgaactttg ttaaatggat
    30061 gggacgacgt tttattacaa aaagagatct gcattcagcg ggcgtttgaa ggaggacaca
    30121 taaattgaga ttgaaacatt ttttgattac cggtattggt ctgatgctta ctggtggcct
    30181 cctagcaggt gcaacttata cattaggcgc tcaaaagagt ctgacttggg ataatggtcc
    30241 tcggttgatc gatatggtta ctgagacaaa aaaaatcaag gatgcaaaca aaatcgtcat
    30301 ccatgcagaa aatcaaacag tttcggtcat acgcggattg gattttgaga taaaaacgac
    30361 ttatgataag acagaaaagc cagaaataaa ggagaaaaat ggcgtgttga ctgtgaatgc
    30421 agtcaaaaaa tcaacaggtg caatcattag tttagaagac acaagtgcac aaatcactat
    30481 tgttgtccct gcagatcatg aattatctga attgacaatc gaagggaata atagtgcaat
    30541 tgatatcaac gaagtatcaa tcaaaaaagt gaatactaag acacatgatg gctgggtatc
    30601 gttcaatgaa tttacaggag gaacaataac tgcgaaagat gaattaggct cacttcgatt
    30661 agatgaggcc aatgtggata acttgatcgt cacaggtgaa aacagcaact tccatctaga
    30721 agacagtttg atcagcaaag aaggaaaagt catcctaaac ggtggcaatt tatctttgca
    30781 tgagatggaa aacagtggct atactatcca aacgtctggt gaatcttata ttgaaaaaga
    30841 ctaccagcca ataacaaata ctttgttaga acaaggacag aaaaagctaa agatcactgc
    30901 taaagacaca tcgatcaata ttacgacgga tcaagaggac aatgaaacag attgatcctg
    30961 tactcaactg gatattttaa gaaaaaacag caaagatcct tccaatcttt gctgtttttc
    31021 atcgcttaac gcacataact atagtaaaat aagaaagaaa atatctaaaa agaaaacagg
    31081 gtgaaagagt atatgaaggt agaagaaggt caaagagaaa agttaaaaac agaaatggaa
    31141 agattacata cttatatcac tcaactaagc caaaccttct atgatccaga caaagaaaaa
    31201 gtgatggtta attacccgaa caattcagaa ggtcgccaat tagagcaagt gtaccatgaa
    31261 gttttcaaac atttattgac ggtgaagaaa gagctggatt attattcttt accgattatc
    31321 gatacaggaa tattgaagta tgatgggaag aaggaacgat ttatctttaa atctgttcgg
    31381 gaagatttgc ctctttcagc agggatggat ctagaggtct tggtagaaga ctattttaca
    31441 gaagaaaagc actgggttcg aacaaaattg gattatttac cgcaggcagc cggagggaca
    31501 caggcaagcg gttggtacat cactgaagac aaagagttag aactagaagg tgtaatggcg
    31561 cgtattcgaa aaaaaaatta aaaaagtaac attagatatt tattgaagga taaaggagcg
    31621 caggaagtag catgagagaa aaaagagcat tttatatcaa tggttatgca gggattgtcg
    31681 gattggtcgt attagcttta gttggattgt ttttcttcta tttaggtatg tggcaagcga
    31741 aagtttgggc acttttttta agtatttttc tttggttgat cacgttattg ttgttaagtt
    31801 cggcaactgt agtcagtcct aatcaagcaa aagtaatttt gttttttgga caatatttag
    31861 gtacgattcg agaaaatggc tttttcctta cgataccttt ggcacaaaaa atgactgttt
    31921 cgttgaaagt tcggaatttc aatagttctg ttttaaaagt caatgatttg gatggaaacc
    31981 ccatcgaaat ctcagcagta gtagtcttta aagtcgttga tacagcaaag gcattattcg
    32041 atgtagcgta ttatcaagat tttgtagaaa tccaaagtga gacagccatt cggcatatcg
    32101 ctagccaata cccgtatgat acattcaatg agaatgattt gacgcttcga ggaaacacga
    32161 cggcagtgtc tgacgagttg caaaaagagc tgcaagagcg tttagcagta gcaggtgtcg
    32221 aagtaatcga aacacgcttg aaccatttag cctatgcaac agaaatcgct agtgccatgc
    32281 tccaacgtca acaagcaaaa gccattttgt ctgctcgaca aaccattgtt gaaggagctg
    32341 tcacaatcac tcaaatggcc ttagagcaaa tcgaagatgg acaagaaatc aatttcaccg
    32401 atgatcggaa agtccaattg atcaataatt tacttgtctc aatcattaca gacaaaggaa
    32461 cgcaacctgt tatcaataca ggcgacatga aagaccgtaa gtgacatact ttttgtaaga
    32521 taggaagaag gagtttagga cggattattg tcttgaactc tttttttagt tgttttaaag
    32581 aaaatgacaa aattgaaaga agaatgatag ttgattcgaa ggcagaattg ttcgcttttt
    32641 tctataatca gtatataaag taagagagaa ggggaaaaag tgaaaaaact tctgatcggt
    32701 ctacttgttt tcatcgttgt ggtacttgca ggggtgaaaa tcgcagatta cgtagttatg
    32761 ggtggagaag aatactatgt acaaattacg acagatggta caaaaacagt ttcaaaatca
    32821 gactctggac aagaaacagt caactataga tatatcctgc ctggctatac gaaagagggt
    32881 aaggaaaaag aactggactt caagggacaa ttgactcgac cgcttcgtaa aggagcatat
    32941 ttaaaaatca cctggaacaa aaataaaggt gtcacttcgt atgaagaagt cgaaaaaaaa
    33001 gacgtgccga aaacagcact ggaaaaacta attaaagggt agggaaagaa atgaacaaaa
    33061 tagtcgaagt acagaatgta acaaaagtat acggaaaaaa caatgagaaa aagacgcaag
    33121 cattaagcgg catcagcttc gatgtagaaa aaggcgaatt tattgggatc atgggcgctt
    33181 ctggttctgg taagtcgaca cttttgaata ttttatccac attagataaa ccaacagatg
    33241 ggcatatccg aatcaatcaa aaagatgtga ccacattaaa aggaaatcaa ctagcagatt
    33301 ttcgtgcgaa tgagattggc tttattttcc aagatttcaa tttattagaa agcttgacag
    33361 cacaagaaaa tatcgctgtt cctctttctt tacaaggcgt cagaccaaaa gaaatcaagc
    33421 aacgtgtcca aaaaattgca gaacgtttat ccatctctca tattttggaa agctatcctt
    33481 ctgagatttc cggtggacaa aaacaacggg tcgccgccgc acgtgcattg atcacacaac
    33541 caacgattct attaggggat gagcctacag gtgcgctgga ttccaaaagt gcccgggatc
    33601 ttttagatac gatggacgaa ttgaatacaa aagatcatgt atcgattctt cttgtgacgc
    33661 atgatccgtt ttctgcaagt tattgccaac gtattttatt catcaaggat ggcggtatcc
    33721 atcaagaagt gaaacgtgga gatcaaagcc gtgattcctt ctatcgagaa atactatcta
    33781 ttcttggaaa cttggaacag tagggggaga ttgactatgc tttggaaatt atcacttact
    33841 gggatcaaga gccgtttaag agactacttg gtgttattct caggattagt tatggcatct
    33901 gctatttttt acatgtttga atcaatggca agcaacgaag cttttttgaa aagtaatacg
    33961 atcgttgcgg ctacagttat cattttccga ttcggttctg ttttactagg gatcatcaca
    34021 ttcgtttata ttttatatgc aaattccttt ttgatgacga tgcggcaaaa agactatgca
    34081 atgtttatga tgctgggagc aaaaggcaga aaaatcgcac agatgatttt ttctgaaaca
    34141 ttcttagtag ggatcgcagc tactttagtg ggttcagctg tcggtgtagg attgacaagt
    34201 atcgtccacc gattattagt ggatcagtta gatctcaata tttcgcattt tacacctttt
    34261 agtattcacg ggttgttgat cactgttttg ttttttgctg ttttgttttt attagctgct
    34321 gttgtcaatg ctttttcgat tgtcaaaaaa ccgattttag cattgattcg tgcggatcag
    34381 acaccaacaa gaatcaagca gcataaattc ttgtttttcc ttgaagtagt actgggaatt
    34441 gcttttctag gctgcggtta ctatatgatg aaacacgtgg ggacctatca agtctttggt
    34501 ataggggtag ccttagttac gatcgtatta ggaacttatt tcattttcca ttctgtgatc
    34561 attttctttt tatcattact aaagaaatca gaacagattt cattgaaaaa attgaacaat
    34621 ttcacattgt cacagttaaa ctttcgtatt cgtgaatata cacaaatgct ctcaatggtc
    34681 gctatgctgt ttgccttggc actgggcgct ttgacggtag gattaggttt taaaaatgaa
    34741 attgcagact tgacagaaaa caattctgga tatgatctag tgatgaataa tcctcgggca
    34801 gaagatcagc aaaaaatcaa agaactttca ccaacacttt ctgcttctta tactcaaaaa
    34861 gaagatgcgg gaacgattta ctataatgca agtgaatttg cggctcaacc attgatcatg
    34921 ataaaacatg aagatggaac accgccgaag atcacgaaag aaaaagttcc tgctaaaaaa
    34981 atgaatgaac tgactgtaca agaggaactt cgaagctatg aattgccgga acagcaagaa
    35041 aaagaaatca aggtagtcag tcaatcagaa tttgatcaac tgaacttgcc acaatccact
    35101 ttacagctag ttcaggtaaa agacttccaa gcaaacctga aaccaatcga aacacttgtt
    35161 gctcaaaata aaatgaacaa tccatctttg caaaaagtag agtacagcaa ccagaaatat
    35221 gaaatgtatg aagtgtataa tggtctattc tctggttttg aatttatggg attcttccta
    35281 ggtttagctt tcttgaccat gcttgctagc tgtttgatgt tcaagatctt gtcaggaagc
    35341 aagagtgaca ttgctcgtta tgaaatgctt gaaaagatag gaacacgacg cgggttgctt
    35401 aaacaatcga tccgtagaga agtaggcgtg ttattcttag caccaggaat cttaggtgta
    35461 gtccatgtct tattcggatt acaaatgttt ggtctattca tgcaaaatcc atacaaagat
    35521 atttgggttc cgtttacgat attcttcgta ttgtatttca tctactatgt actgacgaca
    35581 tggttatata ctggaatcgt attgaaaaag agattgtgaa aaagctgtcc tgcatcaagt
    35641 aataagaaca gccaagcaaa aatagctcct catatttttc gtttggttgg gcttattacc
    35701 gcagatgcaa gcttttgaac accgtttgtt cggaaaaaga ggttgtgaca atatttttgt
    35761 cacaaccttt ttttcacggt cttttattag aatatagtaa attttttctc gttactcacg
    35821 gaataagctg ttaagaaaac ggtttccatg tatactggaa tcagtgcaaa tgaaagaaaa
    35881 gagggtgcaa ggaacatgga aatcaatgaa caaaattttg gcgaaaacta tcacttgatt
    35941 acgatcacga atcaaaatgg gacatctttg tctgtcagtg atcttggggc acgggttgtt
    36001 cattttcaaa caataatcga taatgaaaaa cgagagttga tcttaggttt tgatgaagca
    36061 aaagaatatc tagaaaaaga cccttatatc ggtgcttcaa tcggacgtat ggctggacgg
    36121 attacgaatg gcacattcaa attagatgat gaaacgttcg aagtaaaaac agacccggac
    36181 actggtcatt gtttacatgg tggtgcacct agctttgaag ccaagcagtg gcattataca
    36241 gtcatcaatg gtgaaaacga agcatcggtc attttctatc agactagccc agatatggaa
    36301 aacggatttc ctggaacttt agatgtagaa gtacggtata cgctgacgaa cgatgataca
    36361 tggcgagtga cggtccaagg gatcagtgac cgcaaaacag tattcaatcc tacaaatcat
    36421 gtctatttca atttaaccgg tgatccagca cagtcaatcg acgaacatat actttggttg
    36481 aatagccgat tatttgctac gctcaataaa gatacaacgc ctacaggaga agtagtttca
    36541 gtaagtggca cagcatttga cttccaacgt cctaaaaaat taggtgaggt ctttgccagt
    36601 gattttcgcc aatcaatgat agtgggcggc atcgatcatc catttttgtt gaaaaaacaa
    36661 tctggtttac taaatgctgc ggaattgaca agcccagatg aaaaagtatc gatccaagta
    36721 aaaacagatg cttcaggaat cgtgattttt acagcaaatt ttggagaaga tggaccggaa
    36781 atgcgcggga ataaattagt aaatcatggc ggtatcacat ttgagactca agaactgcca
    36841 ggagcggagc gacttgaaag ttttggagat gtcactctgg aacctaacca agtacgcgag
    36901 tttgtaacgg aatacaaaat aaatataaag aaatagaata aattaaaaag ggagtgtgac
    36961 agtgtcacat ccccttttta atttattcta tttctttaaa ggcagatcaa gccagaatga
    37021 tttgtctaaa cttaacaagg ttagtacagg aacagttgca gctttaactg tacgagtagt
    37081 tgtttctggt atctgtcttg ccgtaaaatt gttccacaaa tcccagattg aagcgacacg
    37141 gaagatggaa gaagcgttgt tgacgcgttt tatcgttgaa aattctaatc ctgtgattgg
    37201 cacgccatct gttgtccatt tgattggcac atcgaatcgc ttagacatat tgaggatttc
    37261 agcgtttgct tcttcagttg ttgctgcttc ttttttcggt tcatcatatt ttgtcaggtc
    37321 gtacgcttcg atgatcgcgt tcaatttttg tgaatattgg cgatctgtag cataacgtcc
    37381 ttccaaatat ttggttgctt ctttgtagtc ttttgtttcc gacttccaag ttggtttgta
    37441 gaaatcagga ttgccagtca gtccattttt gatcaagtcg gcatagtctt ccaaactttc
    37501 cttgtaagaa ggatatttac ggaattgtgc gcggatttgg tagctttgtc cggaactatc
    37561 ttgttcaagt gtattgaagg tcacgctgct tcctttatat gatcctttga taccaaaaag
    37621 gttatgattt ggttcgcttg ataataagct gtttccagat ccactttcaa ggatagcttg
    37681 agccatcatg actgatgcgt agattccttc tttttgcccg atttcctgtg catcatctgc
    37741 aatctttttc aagaactgat cagttgtttg gttttgactg aaatggaacg agccatctaa
    37801 tccatctaaa atagatgagc cgcctgtcag cgaacctgaa gcagcaggta aacctgctaa
    37861 gtttactcgg acagcaaaat caggcgtgaa atctgaaata gaagttactc gaactttatc
    37921 tcctggttga ggcgcatgga taaattgtcc gttcccaata tagataccta catggtgagt
    37981 aacaccggaa gaaggtcccc agaagacgag gtcgccaggt tgggcctgac ttactggaat
    38041 ctgcgtacct gcatattgct gttcgcctgt ccagccaccg atataatgac cggttgcttt
    38101 catatatacg taataagtca aaccagaaca gtcaaaagta tttggacctt ttgctcccca
    38161 tacatatggt tttccaagat gcttgaatgc ttctcgaacg attgcttgtt ggacattcgt
    38221 tgtatttgta ggcaatacag catcaattgg tgattttaca acaaaatcag aagaagcaga
    38281 agatggattc tctataccgc tttgatttgc tgtatttgga cgagatgaag cattgttcgt
    38341 tccgccattc gatgaaccat tgtttggatg gtttggttct ctctgagtat ttccattgtt
    38401 attcgatcca gatgggtttg tttgattcga agaattcccg ctgttcgaat tattgttatt
    38461 attgtttgaa ttatttgaac cattattatt gttgttatta cccacatctg gtttgtttgg
    38521 cgtttccgga tctggtgtac tagggacttc ttcactagga tcagttggtt tctctgttga
    38581 agtatccggt ccagctttaa attctgcagt aatagataaa ttgttcgtac ctactgtaaa
    38641 ggtctttgca tcataattta cttctttggc accattaaca gcgactgaag caatttgttc
    38701 accttcagct ggcgtaatag tgtaagttac cttcgtttcc gctaataaac cttctaccgt
    38761 tccactttcc gtaatatcca aaggttgctg ttcaggggaa tccgctgtcg aagcagtcag
    38821 ttggatctta ccaatcaaag aaggagcaat tgtaagggaa tatgtctcgg ctggcttttc
    38881 attttctgat ggatcagccg gatcaatttc agttggctcg gtcgatcctg ttgttgagtt
    38941 agttgttcca gttgggtctt ctgtaaaaga atccgttgtt tcactagtag ctgagctgga
    39001 tgtagtcgta tctgttgtga ctgtttgatc agctatttga ttatctacgg caaatacggt
    39061 attggtcgac aaaacagacg gagcaatcag ccaagtagca gctagcaaac gtatcgtttt
    39121 tttatttttc ataataaact agtccttttc ctttcattga ttttctgtct tattcagcat
    39181 tcattagaca ttttttggaa cagataatcg tgtcgaaaag ctttttcttt tcataaatct
    39241 gtctgtgtat tctaaataaa acaatttgta aataagcaac gagcattcat tcgtttttct
    39301 ttgacgttca ttttattgca tagaccacct ttgtttgggg ataaacaagt ggggataaaa
    39361 atggttatgc atatgtaaat tataccaaag tttggaaagt atcacaaaaa tttataaaaa
    39421 taatgatcct aaaaagaaaa agactgaaat atgtgataaa catctcatac ttcagtcttt
    39481 ttcattaact attcataaga cattaggtct tcatcaaacc cgctaacgag agtagtgatc
    39541 attgctacga ctagactaac agccagtcct gctaagtacc agaaaaaagt accggaaatg
    39601 aatgcaggca atgtggtcag actaccaaat acaaaagcga tcgctttcac ttgggcaaat
    39661 cccattacag ctccaccagc agctgcacca atgcaagcag caacaaatgg ttttttcaat
    39721 gggatcgcaa ttccgtaaac agttggttcg gtcactcccg caagtaaaat cgaagcaaaa
    39781 gcagaaccgg agatcgaacg ggtttttgaa cgtttacttc gcagaaatac acctaaagct
    39841 gcaccagcca ttccaaaatt ggctgctcct gtcaacggaa cgattcggtc gaacccataa
    39901 gcagagatat tactgatcat gacagggttt acagcccatt ggataccaaa tattaccaaa
    39961 atattccaac caccagcgat gattgcgcca ctgatcggtc cgttaatatc catcatccaa
    40021 gtaattgcgg cagctaaacc ttcgccaagg taaacacccg caggcccgaa taccattaac
    40081 gtcaaaggaa ccgtgataac taatgaaagt aaaggtacaa atactaattg catattttcg
    40141 cgaatatatt ttttgaggaa tttttcaaca aaagaataaa agaaaatacc taaaatcgcc
    40201 ggcatgacag tagacgtata ctgcatcagt actacaggaa tccccagaaa atcagtagct
    40261 gctttgccac tgtctgaaag taaagaggtc agattcggtt caatcagtgc tgcagcaatg
    40321 acagccgcaa tatatccatt cactttaaac gttttggcag cagaaaaagc aagaaagatt
    40381 ggcagaaaat aaaagacggc attcgacgca gcagacaaaa tatgataagt tccgcttgtt
    40441 tcactaagcc agccaatcgt agtcgctaaa acaaccagac cttttaatat accagaaccg
    40501 gcaaacagcg gaatgatcgg cgtaaagatt tccgatatca aaccaaatag tttttcgatc
    40561 ggatttagct tttctttcgg agctgaatga tcgatttgac gcgtcaattc cttgtaagca
    40621 ggagccaatc cctgatccat gattatttct gcatatctat cgagtaaaat gaaatactta
    40681 atggaaggga tttgctgttt taatttttct gcattggcta ctggctgttt tttcaatttg
    40741 atacgaagcc gagtcgcaca tggaaggaca gaatcaatat tgtcttttcc tcccaactgt
    40801 tcaatcagca tatgaatctg ctcggacagt accatctgtt caggattcat tgtcgtttcc
    40861 attagaagac cactccactc actaatataa tattggcgta aggtgtcatt tcgcctgtac
    40921 gaataaatgc atgacagtta ttcaactctt ttttcatttc ttcatgtggg ataaagctaa
    40981 tcggtgtatc tggtaacaat aatttgattt tttccaatat ttccgggttc attgtcttta
    41041 tttcttccgc caattcaatc gattgtacct caagttcttc taaaacgttt tctaaaacag
    41101 ataaaaaact tggaagaccg tttgagacag ccaaatctat tttttcagta ccaaagggga
    41161 caggcatgcc tgcatccccg atacttaatt tatcaaagtg ccccatttgt gcgattactc
    41221 gtgaaatatc tgaattgatt acttttcctt ttttcatgtt tgtttcttcc tctcattgtt
    41281 aattttagac tgctgattgt tctaaagctt cgcggtaagg gatagaaggt tgcgcaccat
    41341 aagactgcac agcaacagaa gaggctagat ttccataaag gatcgcttct ttcaagttac
    41401 taaggtctgg ctgaagtgtg ctgcttaatg cgccaataaa tgtatcacct gcggctgttg
    41461 tgtcaacggc atccacttta aaagcaggga cgataccgtg ttctttttct gtatgataga
    41521 aagcgccggc actgcctagt gtaatgatta ctgttccaat acctaattca tggagttttt
    41581 cggctgctgc gaccaaactg ttatgatctg tcactctgat tcctgtaatg atttctgttt
    41641 ctgtttcatt tggtataatg atatctgtct tttcaagtag ttcagtagga atcgtttcac
    41701 gagctggtgc aggattcagg atcgttgttt ttcctgcgtc ttttgcaata gaaaaagcta
    41761 ggatcgtcgc atctaagcta ctttcaaact gagcaataat aaagtcactg tttgtaatca
    41821 gttgcttgtt ttttaggact tcttgttcat ggaaagcatt atttgcccct gcatggatca
    41881 agatactatt ttctcctgct gcgtctacca taatcattgc ttgtccggtt gtggcgcctt
    41941 ggatttcagc tatcccagat gtatcgatgt tttcttttgt cagtagatct aataactgtt
    42001 gtccttcgct gtcagcccca acgcctccaa taaaagatgt ccgtgcgcct gaacgtttgg
    42061 ctgccactgc ttggttggca cctttacctc cgccagcgtg aaaaatctca tgcgcatgca
    42121 tcgtttcgcc tggcttgggc atgttggtta aacgaagggt agtgtccata ttaatacttc
    42181 caattactgt aaccgtgttc attttacaaa cctccaacta tctcatttat tttgatggga
    42241 aaattatttt ttaaaacgtt ttagtaaaac gttttaatag ttcgataaaa atatagcaca
    42301 ccttgaaagc tatttcaagg gtgcagttga aaatcttttt tctaatcgta caggtaatct
    42361 tttttcttcc cattcttttt ctgggaattg gatccgatct aacaataact tggcagatgt
    42421 ttgtcccaat tcgaagattg gttgtgcgat cgttgtcagt ttcggcttga tatactcgca
    42481 catatctata ttatcatagc caataatgct gtagtcttca gggatgcttt ttccagcttc
    42541 ctctaatccg cgatataatc caaaagctaa ttcatcattt aaagcaaaca caccagttgc
    42601 agcagaatca agaagttctg ctgtgatctg gtagccacct tgttttgaga actgtgtagg
    42661 taagaggatc agttggtcgt gagggatttg gtaaacatca agagcagatt taaacccctc
    42721 aatccgagcg tggacatttt ccggtggatt ttcaggatag acaagggcga tcgtttgatg
    42781 tcctagacta agcaagtgca tgcccgctag gtaaccaccg cgaaaatcgt ctgttcgtac
    42841 ggcatcacta aatccttcag attttttctg atccaaaaca atgaagggcc ggccttgttt
    42901 tttcaaattt tcgttgattg catctgtaga gacagcagaa gtcgcgataa tgaatccatc
    42961 cacacctcga cgtgtgagct cggctagata ttcgatttct ttttgatgat cagaatcagc
    43021 attacataat atcgtgacga aattctgctt atacaagata tcctcaattc ctcgcatcag
    43081 tgtactgaag aatggattcg tgatatcagg aacgagtaca ccaattgttt tcgtttcctt
    43141 ggtaatcatt tgtctagcaa aatagtcagg ctgatagcct aattcttctt tggcagctaa
    43201 aactttctga acagttttcg gactgaattt ctccgtattt ccatttaata tcaaggagac
    43261 agttgtgatt gaaacgccgg aaagtttagc gacttctttg attgtgatct tttttttcac
    43321 catgttcata ctcctatcta aatcctgtgg ttattttccc atgaaatcaa aaagaagtaa
    43381 atgaaaatca cgtgtgccag tacttatttg ctttgttgga tagcttcgat tatttgtttc
    43441 gttgagcgta ctcgtgcagt tttcggaaat atctttttta tgaacaattg atgggattct
    43501 ttgtcacgat cactgcaagc atcttcagca agcacgatat ggtacccgtg ttgaaaggca
    43561 tctaatgcag tagcatatac accgtttgtt gtcgctacac cgcttaaaat gatagtttcg
    43621 attccacgcc ggcgaagttg aagatcaaga gaagtaccaa aaaaagcact tggattgtat
    43681 tttgtgatag tcaacatatt atctgtatct ttcaaagaat ccttcaaaag taaatcagtg
    43741 aattctggag gtacagaagc agtcattcca cccatatcag tttgttgact caaataaggg
    43801 aaagtggaga tgtctacgtt cactaaaact ttcaaggcag cggtacgttt caatgttctt
    43861 actaacaaat cattgtttgt cagaatagat gctgcagtgt gtggagagag tgtaccgtta
    43921 tttacgatct ctttttgcat gtcgatcgcg acaaaagcag tttttgataa atcaaaaatc
    43981 atattttcct ttaaatcatt catgatgttc cttctttcaa ataacaatgt tttttatgta
    44041 agtaaatcat aaatcgttta tttgtcaact aaattaaagg attcctttct ttagtctaga
    44101 gaaattcagt ggtaaaataa ataagtgtga gaaaacgcat tcgatgcata gatatagcga
    44161 gaaatatcgt gaaaatggag gaatcagagt gaagtatgtc gaagtaaaaa atgaatacaa
    44221 acgatacaaa atgggagaaa cgaccattac agcaaatgac gatatttctt tttcaattga
    44281 aaaaggcgaa ttagtgatta tacttggtcc aagtggagca ggaaagtcaa cgattcttaa
    44341 tattttaggt gggatggata cacctgatga aggtcagatc attattgatg acacagatat
    44401 tgcgcaattt tcagataaac agcttactgc ttaccgacga acagatgtag ggttcgtttt
    44461 ccaattctac aatctcgttc ctaatctaac agcaaaagaa aatgtggaat tggcaacgga
    44521 agtttctcct gatgcgcttg atcctgtaga ggtattgagg caagtgggcc tagctcatcg
    44581 attgaataac tttccgtccc aattatcagg aggcgaacag cagagggttt caattgctcg
    44641 tgcactagct aaaaatccca aacttctttt atgtgatgaa ccgacaggcg cgctggattt
    44701 tgaaacgggc aagcaagtat tgaaattatt gcaaaacgct agcagacaac acggcaatac
    44761 cgttttgatc attacacata attctgcttt agcgcccatc gctgatagag tcattcacat
    44821 taatgatgct aaagtaaggt ctgttgaatt aaatgatcat ccttcatcca ttgatgagat
    44881 tgtatggtag ggggatttta tgaaaacaag aacatatctt aaagcaggtt ttcgcgaaat
    44941 tcggcaatct aaaggacgat tcattgcaat catccttatt gtcatgctag gaacactttt
    45001 atttgtaggt gtcaaaactg ctggacctgt catgcaaaaa acgatggatc actatgttgg
    45061 tacagcagga ctttctgatt tgcaaatcgt ttctactggt ggcttgacac aaaaagatat
    45121 tgctcaagca gaaaagatcc cagatgcaaa agtagaaaca ggaaaacaga tctattattc
    45181 caatactggc aaaaacgaag tgattcaaat attttcttat aacaaaaata acaagcagaa
    45241 caagctacaa ttaactgatg gaaaactccc ggaaaaacca aaccagcttg tattggatga
    45301 aaaagcggaa gatgaagggt ataaaatcgg tgatatttat cagattgatt cagatgaatt
    45361 gaaagaaaaa gagtatacca tcacgggctt tgtccgttct ccattgttca tcaacaattt
    45421 ggagagagga tacgcgaacg tcggaaatgg tagcgtcgat tattttgtct atttacctga
    45481 atccgttttt aaaacagata tttattctgt cttatatctt gattttacaa acgtaaagaa
    45541 tttgaatacg tacagcaaag cttacaaaga taaaatggag caaaatcaag aaaaggcaga
    45601 aaagtattta caagatcgac ccgaagaacg cttagaagag ctgaaaaaat cggccaacga
    45661 agaattagaa ccggcacagc aaaaaatagc ggatggcaaa gcacaaacaa cgcaagcaag
    45721 aacacggtta gaagatgcta aaaaacagtt agcgcaacag tcagcaacta tccagcagct
    45781 tcctgaagcg caacgaacaa tcgctgttca aacattatct caacaagaag ctcaacttgc
    45841 tgaacaagaa aggcaattag ttgagaaaga acgtgaactg gcctctgcag aggaagaatt
    45901 gaatcgaaat gcagaaaaaa ttgaaaattt aactaaacca tcatacctat acaatgaacg
    45961 ttcagaaaat gtcggttttc aagaatttgg tgatctgtct gatcgtatcg ctgcgattgc
    46021 caatgttttt cctgttttct ttttctttat tgccgcattg atcaccttta cgacaatgac
    46081 acgtatggta gaagaaaacc gcagggaaat cgggacatta aaggcgttag gttatacgaa
    46141 agttgaaatc gcaaaaaaat atgcaatcta tgcaagtcta gcctcaggga taggtattgt
    46201 tttaggaacg atattaggaa cgaatctttt gccaaggatc atttttgagc tgtctaacga
    46261 gcggtatgat attgggagtg cgcttatttt ttatgactgg ccgccgattt tacaagcagc
    46321 tgccgcattc ttcattgccg catttggcgc tgcaatgatc gttttattca aagatttaag
    46381 agaacggcct gctgcattgc ttcaaccgaa agcaccgaag ccagggaaac gcatttttct
    46441 tgaatacatc actccgctgt ggtcacgcct tagctttaat caaaaaatca gttaccgaaa
    46501 tctcttccga tataagtcaa gaatgcttat ggcgattatc ggaattgctg gatgtgccgg
    46561 gctgatggtt gcaggcgtgg gattgaaaga ttctctaagt tctgtttcag ccaaacaatt
    46621 tggaccgatc attgactatc aagcaatcgt tacattggat tcatccacgg aagatagtcg
    46681 tcaaaaagca gcggatatgc tgcagaagca agaaaaagta aatgagatcc tagctattca
    46741 tactcaaacc gtagaattga gaaaaaaagg acatgcttcg caaagtctga cagtgatcgt
    46801 accaagtaaa acagctgatt tggatcgttt tatccattta actgatcttg aagagaaccc
    46861 acgctccttg cctaaaacag gaatcgctat tacgcaaaaa gtagcagaac tatttgactt
    46921 atctacagga gatcatattt cgctttatga tgaagatcaa aaagaatgga aagtcgaagt
    46981 aaaagaaatc gtgaaaaact atctaggtag ctttatttat atgtcccctg aatattatgc
    47041 ttcagttact gatcaatcga tgatggataa tgcatttttg ctgcgtacag ataagatgac
    47101 aacaaaagaa gaagaaatgc tttccgagaa actgcttgcc acagacgctg tgacaaatac
    47161 gtctttcatg tccaaacaaa tcgaaacgca agaagaatca atggcgaact tagactcggt
    47221 tgtcttaatc tttgtcgtat tatcaggact gctggctttt atcgtcttgt ataatctaac
    47281 taatatcaat atttccgagc gtgtacgcga attatctaca ataaaagtcc ttggattttt
    47341 tgataaagaa gtcacgatgt acattgttcg agaaaatatc atctttactc ttttaggaat
    47401 catcggagga tttggtgtag gatatatatt gactgacttc atcttgcaac aagcgtctat
    47461 ggagaatgtc atctttccat tagtgatcac atggtgggct tatgtcttat cagcaggatt
    47521 aactatcgta tttacggtta ttgtgatgat tgttacccat ttcaaattaa agcatatcga
    47581 tatgattgat gcgttgaaat cgaatgaata aaaacagagg ttgtgaaatc agcggtttga
    47641 cctgagtatt agagaaacaa acggcaaaat agtttttcat attttgccgt tttttgagct
    47701 aataccgaag gacagctgat tgaacaccat gaatcagagg ttgtaaaaaa gccgtcctgc
    47761 atcgagcaaa aagaatactc aaataaaatt agctcctcat gttttacatt tgagaagact
    47821 gattgccgta gataaaagct tttgaacacc atttatagaa gaaacaagaa tattttgcta
    47881 ttttaaacaa gaggatagac aaatacatgt ctgatctctt gttttttatt gggcaacaga
    47941 cctcttagaa tgtataaaga taaattttac aaacgctttc ggttcagtta taataataaa
    48001 tgataacttg tatatataag ttgtggtagg taataaatca gttgaatgga ggtaaatatc
    48061 catgacattt aaagacaaag tcatttacca aatctatccc aaatcttaca aagacagtaa
    48121 tggtgatgga attggagatt taaaaggaat caaagaaaaa ctcccgtatc tgaatgatct
    48181 aggcatcgac atgatttggc taaaccctat ttatccaagc cctcaaaaag acaacggtta
    48241 tgatatctct gattacacag ccatcgatcc tatctttggt acgatggagg aattcgaaca
    48301 gctaatagcc gaagcaaaga aataccggat agaaatcatg ctcgatatgg tgctgaatca
    48361 cgtttcgaca gaacatgaat ggttcaaaaa agcactagca ggggaccagc attatcagga
    48421 cttcttcatt ttaagagaag agccaacgga ttgggtatca aaatttggtg gaagtgcttg
    48481 gtcgccattt ggagatacgg ggaaatatta tttgcactta tatgatcgga cacaagctga
    48541 cttgaactgg cggaaccaag cagtaagaga ggaactattc aaagttgttc gtttttggat
    48601 ggaaaaaggg gtaaaaggat tccgtttcga tgttatcaat gttatcggta aagacgaaca
    48661 attgaaaaat aataaagaaa atgatggcaa acctgaatat acggacaaac caatcaccca
    48721 tacgtatcta aaagaattga accaagcaac gtttgggacg gattccacta tcatcacagt
    48781 cggtgaaatg agctctacga cgatcgaaaa ttgtatcttg tatacagaac ctagtagaga
    48841 agaattatca atggtcttta atttccatca tttgaaagtc gattatgaaa atgggaataa
    48901 atggtctact cctccatttg attttgcaga attaaagcga ctatttcata catggggaga
    48961 aaagatgagt gagggtaacg gctggaatgc tctatttttt aataatcatg atcagccacg
    49021 tgcgctcaat cgatttgtag ctatcgatca gtatcgaaaa caaggagcag agatgctagc
    49081 aaccatgatc catttgaacc gtgggacgcc ctatatttat atgggagaag aaatcggcat
    49141 gatcgaccca gactattcat cgatttccga ctatattgac gtagaaagtt tgaatgctta
    49201 taagttactc cttgaacaag gattcacaga aaaagaagcg tttcgtcgga tcaaagcaaa
    49261 atctcgcgat aactctcgaa cacccatgca atggtcagac acagaacaag caggatttac
    49321 tacagggaaa ccttggttaa aagttggagg caagctagaa gagattaatg tagaaaaaga
    49381 actatcttct gaagattcta ttttgtccta ttacaagaaa ttgattcggc tgagaaaaac
    49441 atatccaatc gttgcacaag gagattatca tgcttatgaa gcaaatcatc cggaagttta
    49501 tggctttctt cgccaatttg aaggacagca gctgcttgta ttaacaaatt tctatgataa
    49561 agatacaagg atcgccatcc cagaaggatt cacagaagcc aatattctta tcgataatta
    49621 ttccgatact gttcttcatc aaagtctgga gctaaaacca taccaggcaa ttgctttgct
    49681 gaaaaattaa aacaaaaaca caaaacgtcg ttcctacgag ctattctcgt aagatcgacg
    49741 ttttgtgttt tatttaaaat aatcttcttc agaaaatgaa gagttttcat actctccttt
    49801 atcgccataa aatttattgt agcgttgttt gaatttacgg aaaataaaag taacgagtaa
    49861 tttgactaac gtatagatag gaataccaaa aataacgccc acaattccca ttagatcacc
    49921 catgacaagt aaaacgatta agatcgtaat cggatggatc tgtaaacgat cacccattac
    49981 tcgaggaatc accaagtcac cgtggagaag ttgtacggca aaccagacaa tgacaaattt
    50041 gacagccata aaagtagagt cttggaatgc aatgatcaaa cctggaaaga aggcgataaa
    50101 cggcccaata tatggaatga tacataacaa cccagcagaa atagctaaaa cactagcaaa
    50161 ttctaatccg atcagtaaga aacaaaccca gtagactgct ccaaggataa atgaagcaat
    50221 gatttgcccc tttagaaatg aacccaattg ttgattagca atctttgtca aatttttaaa
    50281 atctgtacga aatgctggtg ggacaatcgc taaaactgac tgataaaatt tttgaggatc
    50341 tctcaaaagg aaaaaagcga caattggacc agtaaataaa gtaataaaaa tagctgtaac
    50401 agttgaaaaa atgttgctga tccgttgtgc gccactttcc caataatttc caataaatcc
    50461 agctatatca gacgtcacgt cgtcaataga agcgaaaaat tgattaaatg aatcggcaaa
    50521 aggtgttttc tccaaaaatt gtcggagact ctcttgaaaa tcttgaaaca aatctggcaa
    50581 actactgatc aatgtctttg cctgttcttc aagaaaagga ataagccata tgcttccaag
    50641 ccccaataaa aataaaataa tcacataaac gataatgact gacaagttcc tcgaaaggtg
    50701 cttgctcaaa cgtttgatga ctggttccaa aagataatac aagatcagtg caaacaataa
    50761 tgggggcaag atagtagcga taatgattcc gacaggcttg aatataaacg agatctgatg
    50821 gaaaaaataa atgatcagcg caagtaagat aactattcct aaaacatagt aagaggtttt
    50881 tcctcctaaa aagcggatca aacgattcgt tgtatctgtt tcttttttca ctctttttcc
    50941 tcctttatct ataacttcat tatagacaaa agcgggtata aaaggaaaat gatagaggtt
    51001 gattgcaaaa atatcgtcaa tcattcatat aaactttctc atcaattaaa ataagaaaac
    51061 gcttgacagt tcttttaacc atatgataaa ttaaatcctg ttgctaaaac gtaactatta
    51121 cggtttgcga aaagcgaatc ggaacattca aatgaaagaa gatgagaaga ggagtgtcat
    51181 aaatgaaacg attgataggt atattggcca tgctggtttt agcaggtatg ttaactgctt
    51241 gcggggcaag tgggaaagcc gaggacagta aagaaaaatt gagcgtgatg acgacctttt
    51301 atcccatgta tgattttaca aaagcaatcg tcggggatga aggagaagta gagttattga
    51361 ttccagcagg gactgattcc cacgattatg aaccttctgc taaagacatg gcaaagatcc
    51421 aagatacaga tatctttgtt tataatgatg aaaacatgga aacatgggtc cccgcaatcc
    51481 aaaaaacatt acaagaaggc aatgtccata cgataaaagc gacagaaggt atgcttttac
    51541 ttccgggaag tgaagaagga catgatcatg accatgaaca cggggaagaa ggccatacac
    51601 atgagctaga cccacatgta tggctagctc caagtttagc aatcaagcag gtagcaaaca
    51661 tacgtgatca gctgattgaa gcttacccag aaaaacagga agtatggaca aaaaatgcag
    51721 cagcctatac cgagaaactt caagcactcc atcagcttta tcaagaaacc tttaagcaag
    51781 caaaacaaag atcttttgtc acgcaacatg ctgcattcaa ctatctagcg ttagaatatg
    51841 gattgaatca agtatcgatt gctggtcttt cttctagtga agaaccgtct gcggcgagaa
    51901 ttgctgaact gaaacacttt gttaaagaac atggaatcaa ctatatttat tttgaagaaa
    51961 acgccaaaga tagtattgcc agaacgttag caaacgaagc aggtgtatct ttagaagtat
    52021 tgaatccttt ggaaggattg acgaatgaac aaatagaaaa tggagaaaac tatctttcta
    52081 tcatggaagc aaacctcgaa gcgttgaaaa aaacgacaga gacagaaaac ccgctagaag
    52141 atactttgac ccccaaaaaa gaaaagagcg tctacaacgg ttattttgaa gacgaggatg
    52201 tacaagatcg ctctctttca gattgggcag gaacttggca aacagtagat acgtatgtag
    52261 aagatgggac ttttgatcct gtttttgaat ataaagaaaa attgaatcag gataagacag
    52321 cacaagaata taaagaatat tatacgaagg gctatcaaac agatattgct tcaatcaaga
    52381 tcagtgagaa agagatggca tttacgttta agaatggaac aacgaaacgt tcaaattatc
    52441 gttatgtagg gaaagaaatc ttgacctacg aggcaggaaa ccgtggcgta aggtatctat
    52501 tcgaagcaga agataaggaa agtggcgctt ttagatatat tcaattcagt gatcacacga
    52561 ttgcaccggc tgactccgaa cattttcatt tatatgcagg aaatgaaagt caagaagtat
    52621 tgctgaaaga aatggagaat tggccaacat tttatccaga tacaatggat ggacgtgaaa
    52681 ttgcacagga aatgcttttg cactgatagg caaaaaagaa ccgaagggtt tggatcggct
    52741 ggtcatttag tcggtccaaa ctattcggtt ctttttatga aatcaatttc tttaatccac
    52801 ggatagaggc tgggatggtc tcgccgtttg ccaacgtgac ttctctggtt tttttattaa
    52861 tcgaccgcac attttgtgta ttgataacat aggatttatg acaacggata aaattccgat
    52921 gcattttctc gatttctttg atcttctcat agaattgtaa ttgggcatga gtcaaatgga
    52981 cttccagttt atgtggcgct cctagcgaag tagaaaaata ttggatgtct ttgatcggta
    53041 aaaatttgat ctcatcatta aactctattt tgaagatatc tttttggatt tgggacattt
    53101 gaaaatcttc gaaaattttg ctcaggatat gctcgacatt ttcttttaaa tcataaagat
    53161 cttctttgac gatataatca gtcggttcga tgttgctttt taagattttc atcgacattt
    53221 ccgtatggga agtcacatag attatttttc ctaaaggatc taattcacgg atcaatttac
    53281 cgatcgctac accatccatt tcactgtctt ctagttcgat atctaaaaag taaataccaa
    53341 aagaagaagt tctgatcttg gctgcattga gaagttcttc cggatcagag gtagaaatat
    53401 ggacataact gtctaagttt tcaatcatga ttctattttt gatcaccgtt gataaaactt
    53461 ctaattgttt tggatcgtct tcacaaatat aaatgggaat catatcatta ctcctttatt
    53521 ttatttgtat ataaatcgtt tgagaaaaac gctggttttc aattgatgtt tcaaggaaaa
    53581 gataaggatt ggtctttgtc aattcatcca agataaacaa gccaaggcct tcgttttttg
    53641 gatttgtttt tgttgagaac cctttttgtt tcaactggtt taacggtaat gtatttgttg
    53701 ttgtattgat cacacgaatc atcacggaat gattcttctt gagtatggtc aattcgattt
    53761 ttttcttctt tgcagcacta gctccttcaa tcgcattgtc caagataata ccaagcatac
    53821 gtacaaggtt taccgtatgt ttcgtatcca gttcgattgg ctcaggaaaa tgaagctgga
    53881 cgatcaaccc tttttcctgt gccatcatga gttttaatga cagtaaacta cggatctcag
    53941 gaactttcat attatccaac atacttagat tggccggaaa aaggttcatc atctggcgtg
    54001 taggtaatat cgtttgatca taataagacc gtaatccttc taagtcgcct tctgaaatat
    54061 agctgtgaag agaaaaaagc agattttggt aatcatgttt gaattctctc aagtcttgat
    54121 agtttttttc tagatctttg atataatcct gttgcatcct gacttgttgc tctaataact
    54181 gatcagctaa tttcttatta gagattttcc aataataaac caagatgatc aggccaacac
    54241 acagatatag aatgaaaaaa ctcgtattca aagctaagac atcaggtgtt tcaccagaaa
    54301 aacgggtata aaaaataatg atatagtatg taaataatat caatgtcccg atcgtaccga
    54361 tcatacggcg gtccacagtg tgaaaccaag tctctaacga tttttttaaa caaaaagcta
    54421 ataaagcaga taaaaaagcg gataagacaa tgtgaaaata ctgcaatgaa tctcctggtt
    54481 caataaccga agatttcaaa acaaaaaaat cgccgatgct tgttaagtga tctcctaaaa
    54541 gcgacgtcaa taacccaaaa ggaagcgcgt aaaccaattg ttgacgcgaa gtcgaaaaga
    54601 agaaaaaagt aagcatcagc attcctatag caattagagc agtaaaaatc cctaaaatcg
    54661 aatagaccca tccaatcaaa atacaagaaa tcagaatgac tcccgcaaac agatatttgt
    54721 atcggatgtg atggtcaatc aataagatac aaattgtgta aatcaaatat tgcaacgcta
    54781 tggaccataa aaacataaag tacagctccc attgattttt accaaattat agcacaattg
    54841 gcgtattatt tttttaattt ttcagggatt ttgaattcag aactcatacc aaagcagcag
    54901 ccagatacaa aaaagtcaga taagttagtt aattgtttaa tgattgtttt tttcatgaaa
    54961 gattcctcca aaattcatca agtagtttgt aataggaagc aacgtagcta tttctaaaac
    55021 aatcccaagt agcaaatagg tagaaaagta agaagctgag aaaaataacg taatgagaga
    55081 aaaaattaga aacatgctga tcgccttctt taataatggg ggacgtttct cgggttcaat
    55141 gggattgatt gctgtacctc ttgatccata gcgaagcagt aacaaaaagc agctgattaa
    55201 caaaaagacc atcattggga aggagatagt caattgcaga tgtttcatca ccaagggaac
    55261 gccccataaa taaagtagtg tccacagcag acaaacgaat tcagagtcgg aatgcaatcc
    55321 ataagcatat ctgcggatgc agatataaga aagaaaggtg attcctgttt ccgcccatga
    55381 gcctgtcacc agagaaaaga ctagaacgac cgctagtttt ccaagattat tcaataaaac
    55441 ttctaagaca aattttactt ggacatacac catatcttct tccgatttgt ctccgctgaa
    55501 taaggcttct aataatttgt tcacaacttt atctttcatc tcatacgtac ctccaccaca
    55561 aattttatgc taaaaaaaat aaaaaacgtc ttttgtttca taaaaagtgg ttttgacatc
    55621 aaaaccgtca tgatctccta aaaaaatctt cgttttccaa gaaccttacc aaaaaaagtg
    55681 acagttttga tacgaaaagt actttttatg acaagtttgt gctttttcga gtgatttatg
    55741 ttaaaaaatt actgacctta taaaaggtga tggagggatt cttatggaaa atgaacaatt
    55801 gtttgaagtc ggcgaaacat atgcatttaa atctgattta tttgaatcac caataaaagg
    55861 aaaaatagaa aaaatctatg aaaatagtgt gatgatacgt gtcatgaaat gcgcagtaga
    55921 agacaatgat accgctcata atctgcactg gcagttagtt gtacgcaaat caagtacaat
    55981 agaagaataa aaacagataa aatgttgaga gcataaagag gttgtgagtc tcccgtttag
    56041 ctctgagtta caaggaataa tgttaaaaaa cagcttttca tgttttatga atattgcctt
    56101 gtgaccgagg tgttggcagg agaatactgt ttatttgaaa aaagggctgc gacaagactt
    56161 ttgtcacagc ctttattttc atgaatagga gttacttttg gctactttta gagaagtagc
    56221 ttttaaggag cagataaagt caaggctttt atttctataa atgaagtagt aaaatgaaga
    56281 acagatttta ttacaggaag gatgccgata attgtgatca ttgttgcagg aacgatcggt
    56341 gcagggaaaa gcacactaac tgaaatgctt gcccaagatt tagaaacaaa acctttttat
    56401 gagaacgtgg aagataatga agtattgccg ctattttatt ctaatccaga aaagtatact
    56461 tttttattac agattttctt tttgaacaaa cgctttttgg caatcaaaga tgctttcagc
    56521 catgatgaca acgtactaga ccgctccatc tacgaagata gtatgctgtt tcatttgaat
    56581 gcagatttag ggcgtgtttc tgaagtagaa gtaaagcagt atgaaggtct tttagaaacg
    56641 atgctgaagg agttagaaga aatttcgcca caaaagaaac cagatctact ggtttatatt
    56701 cgtgtatcct ttgaaactat gttagcgaga atcaaaaaaa gaggccggga atatgaacag
    56761 ctagaacaag atcctgaact ctattcctac tataaagaac tcaatcgacg atacgaagag
    56821 tggtatgaac agtttgatat atgtcccaaa atagtgatcg atggggacaa atatgatttc
    56881 gtagccgatc cggcatgtgg agaacaaatc gtacaagaaa tcaagatgcg ggcaaagaaa
    56941 atgacagaag aggcagatgc ccagtcgatc cgctacacta caaataaccc gaaagcaaag
    57001 ggaatcttta caactaaata atataaaaac taagcaaatt gctcactcgc agatatttct
    57061 ctgtgagcag catcttgctt agtttttttg attcattgag atcaaatagt gaaccgattc
    57121 gtatgataaa attgccataa atgaaatgtc tgagtgaggg ccatgatcaa aaataaaatg
    57181 gaaacgatca aaatcgaatg ggcgccaaac agatgatgac agaaaacaag gacaatagct
    57241 cctgcgataa aggcaagaac gacacttaga tagtggaaaa atcgatcaaa atctgctttt
    57301 tctttagaaa tacaataatc atataagttc gttgctaccc cttttaaatt tccagttgta
    57361 aataaattag tgtaggcacg cccgttgatt ttatcaaaag ctacccactg gatcgatgca
    57421 gtaaaagcaa tcaaaatcgt tactaatgcg ggatgctcat ggacgggtgt caaactaaca
    57481 aagaaaaaaa tcactgcttc ataatataga acaaacaagc gccagaaatg tttttctttt
    57541 tttctaaaat aatcaattag atactttgtt agaagaatcc ctaagaaaaa gaaaagggta
    57601 gacaatactt ttttaccaac acttagccat tctccgtcaa atgcttggat gatcgataga
    57661 atgatattgc cagtttgagc agaggcaaaa gcaccatatt ggatataagt ataactgtcc
    57721 atggctcctc cgataaatgt cagcaaaagt cctattgtac gcccctcgtg aaaggaagtc
    57781 tgcatttttt tcatcacctt ttatgaatat ttttgtcttc cttatcttag cataaacgat
    57841 tgaaaaaaaa ggaaaaattt tcagaaaact aaaatcatat cgcttcccat tttcattttt
    57901 agaaaggtct gttagtataa agaaaaaata gacaacgaaa ctttaaataa ccaacttgaa
    57961 ataaacaaat tcaaagaaga aagatgggaa ggaaatcaat cagttgaatg aaaaagaaat
    58021 tctccgatta caaaaagaat tgaaacgctg ggagaacaag tataaaaagc ttcaacaagt
    58081 ctttcggcta caagaagaaa tcattgctac ctatgaagcg gcttatggcg aagcacccgg
    58141 acttattgag gaagaagtac aagtaaaaga aagtgaagga aacagctctt tctttaaaat
    58201 gatggagaaa cgttcctata atcgcttcaa tcaagaacaa aaagcagcta tcacatatga
    58261 tatgaagaaa catcttcgaa tcatagcagg agctgggagc ggcaaaacgc aaacaatctg
    58321 tgcaaaagct gtttatctga tgacgcaaaa acaagtagac gaagaacgca tactaatgat
    58381 cacttttaca aggaacgctg caaatgaact aaaaaaacga gtagataatt tcagccagag
    58441 aaaaaccgct gtccatatcg gaacattcca tagtatcttt tttaggatat acaatgaaat
    58501 ttgtcgaaaa tttcctgaag tagcaatgca aggaatacaa ggagactttt caaaggatac
    58561 tgcacaaaaa gtgaatgctg ttttgcaaca gctgatacgt aaatataatc tttatatatt
    58621 tgatcaatat ggagaaaaaa cgattgcttc tcggttagac tattggcaga atatgaacct
    58681 ttcagtagaa gaaatggttc agttagttaa agaaaaatat gattccattg ataagaatgc
    58741 acgacagccg atatcagaac gactgtatgg attgctcacg gaactccaag aacaaaaaag
    58801 aagccagcaa ttgctagagt tcaatgatgt actccaaaat ctgaaaagcg ctttggagaa
    58861 tgaggagatc cagcattata tcggccaaaa atatgattat ctattcattg atgaatttca
    58921 agatactaat ccacttcaat gggaaatcgt gaaacggatg acaaaggaaa acaggatcaa
    58981 gttgattgtt gttggagatg atgatcagag tatctatgga ttcagaggat cagagccagc
    59041 atacatcaag aactttgaaa aagaatatcc taccaaaact cttttcttat taactaatta
    59101 tcgttctcgg gcagctattg tccaaggagc aaatagattg atcagctata ataaaaatga
    59161 tcggatacca aaggcgatga ttccagcaca aaaagaagca ggtgttatgg aagcctattt
    59221 gttttctgat actaaagcag aaagtcagtg gctaatcaaa caaattcaga catttattca
    59281 aaaaaatggg aaatataagg aatcaatcat attataccga tcagcttcac aaacgcagca
    59341 gcttgtccaa tctctgctga aaacgaatat tccttttgta ctggaagcag atagtccata
    59401 tgaaggtatc tttggtatca agtctttcca acatttctat caaaaaattg ttcattggca
    59461 aacagcactg aatctgcaaa agaaaaatca ggcctaccag caattgctcc ggcagctgat
    59521 ggcagactgc tacctgaaaa aaagtgaatg cgatcaatac ttttctccta aatatcaaaa
    59581 tatagccgtt gcagattata ttttgtcgat aagccccaat ttaaaatcga aatctgcaga
    59641 aatccgagag tttgaggaag cgttgcgtaa aacagaccag catcaagaaa tctattcgct
    59701 tgttcaaagc tatcttcatc tgccacgtat agctaaggaa atcgaccaga gtgatcaaga
    59761 atggatacga gaagaagtaa agcagcatgc tactttcaga agactccaag ccttatcgca
    59821 agaaacccaa gcgacagcta aagaattaaa aacccgcttg attgcttaca gacaaggaaa
    59881 acttgatgca ctatgtatcc agagcattca caaaagtaaa ggtcttagtt accgaaatgt
    59941 ctttttgatt ggttgtaacg aaggaagttt gccttataac ggagcgacag aaaagaaagt
    60001 aatcgacttt aatgaaataa aagcagaacc agtaacgacg atagaagaag aacgaagact
    60061 attttatgtt gcgatgacta gagcaagaaa tcgtctgtat ctatgtgtac ctcaaatgaa
    60121 aaattcaaga aaattgaaag tatcgagatt tatcaaagaa accgggagtc gtgtgaaaaa
    60181 aggaaagtga tagaagagag ggtgtgacag aagtggtcag tttcaagaaa gaagaaggaa
    60241 tgtacgaaaa ttgcttctca aatttttgtg aaatttcagc ttattttcga agaagctatt
    60301 tctggaacac agtttattcg gaa
//
LOCUS       DACGEU010000008        52308 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.008, whole genome shotgun sequence.
ACCESSION   DACGEU010000008 DACGEU010000000
VERSION     DACGEU010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 52308)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52308)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52308
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.008"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            558..3197
                     /locus_tag="IXR40_000458"
     CDS             558..3197
                     /locus_tag="IXR40_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAQ4360333.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(3365..4063)
                     /locus_tag="IXR40_000459"
     CDS             complement(3365..4063)
                     /locus_tag="IXR40_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HAQ4360334.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            4281..5426
                     /gene="tgt"
                     /locus_tag="IXR40_000460"
     CDS             4281..5426
                     /gene="tgt"
                     /locus_tag="IXR40_000460"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010769586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HAQ4360335.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            5523..5903
                     /gene="yajC"
                     /locus_tag="IXR40_000461"
     CDS             5523..5903
                     /gene="yajC"
                     /locus_tag="IXR40_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HAQ4360336.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            6208..8805
                     /gene="adhE"
                     /locus_tag="IXR40_000462"
                     /gene_synonym="adhC"
     CDS             6208..8805
                     /gene="adhE"
                     /locus_tag="IXR40_000462"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HAQ4360337.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            9034..10140
                     /locus_tag="IXR40_000463"
     CDS             9034..10140
                     /locus_tag="IXR40_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HAQ4360338.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            10157..11185
                     /locus_tag="IXR40_000464"
     CDS             10157..11185
                     /locus_tag="IXR40_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HAQ4360339.1"
                     /translation="MKKTSLLFAASSLSLGLLGLSGCGNNSSVATVADADVNEIVTLR
                     FAYASNSQPVIDAMNEFGRLVKEKTDGSVQIQYFPDGQLGGERELIELTQSGAVDFTK
                     VSASALESFSKDYSIFSVPYLFNDEEHFFKVMDNEEIMEPIYQSTKNLGFTGLTYYDS
                     GQRSFYMVDGPIHTPEDLEGKKIRVMQSETAIKMVELLGGSPVPMGSDEVYTSLQSNL
                     INGSENNEFVLYTAGHGGVAKYYSYDEHTRVPDIIIMNDAIKEQLTDEQEKAIEEAAK
                     ESTVFEIEAFAKAIEEEKALAQEEHGVQFNDVDNTPFREAVAPLHDIFKNDPTYKDLY
                     QKIQEQGA"
     gene            11191..11670
                     /locus_tag="IXR40_000465"
     CDS             11191..11670
                     /locus_tag="IXR40_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HAQ4360340.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKAHLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            11686..12981
                     /locus_tag="IXR40_000466"
     CDS             11686..12981
                     /locus_tag="IXR40_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HAQ4360341.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGALWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKI
                     IKEAIPSLLLIVIIIGGILTGIFTAVEASAIAVIYSLLIAMFYYKTVKLKDIPNMLFQ
                     SVAMSGTIMFLLATSSMMSFAMAFTGIPQAISSLIMGVTDNKFIILLLVNLVLLLVGM
                     FMDVAPAILIFTPIFLPIVTSVGVDPVHYGLFSIMNLCVGSITPPVGTGLYVGASVGG
                     VKAEAMLKPLLPFYGVILVVLFLITYFPQIVMWLPNMLS"
     gene            12992..13816
                     /locus_tag="IXR40_000467"
     CDS             12992..13816
                     /locus_tag="IXR40_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HAQ4360342.1"
                     /translation="MLNITIRGHDLSEVQTIEDLAEKTKEQGIHTLQLALGLSFPETP
                     SGANEINSGMGNYVKRVLEKQEVTVGILSCYINMIHPDLTIRQELLTKFEQYLRYASS
                     FGASMVASETGCVLPEIQYTEENFTDEAFAEAVSVIRRLVKAGEKYQMMVGIEPGLNH
                     PVYSLARVEQLIQAVDSDYLGIILDPTNLITSSDYQEQVQLVEEAFERFGEKICAVHL
                     KDFRVEQEKIVPVNLGDGVIEYTKIKEIIMKNRPYLYVVLEETKDDGIRYGRSLLE"
     gene            13981..14880
                     /locus_tag="IXR40_000468"
     CDS             13981..14880
                     /locus_tag="IXR40_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAQ4360343.1"
                     /translation="MLQKKISGEQVNTMVSDQYEIYHVKDVVSQNKTIYHHHDFYEIH
                     ATLKGEATFYLNGRQFTIKAGSVLLIHSNDLHRIVRQSSDVFERVYIFVTPSFLESRS
                     TPWSNLSACFQPMGEKRSRVLQIEQEVLKQKLSFIDHPPDKKIYGEDIKYEQALVEYL
                     IFLNQVVQKEESAQEQNAVVPNERVEQMLQYISKNLSHPLSLEEMEKQFFVSKYHITR
                     EFKKYTGFTFHQYVMKKKLIYAKHLLREYRSSSAVYSKSGFSSYPHFLKAFKREFGIT
                     PKEFLKRDTQKQLVHYEHFEDEQ"
     gene            complement(15006..15875)
                     /locus_tag="IXR40_000469"
     CDS             complement(15006..15875)
                     /locus_tag="IXR40_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAQ4360344.1"
                     /translation="MDYWEKANHSWSEDSKRVILTPTQRSRNLFFYIQEIGYFKAPIP
                     YYTERAHLPSYLIKFTLSGKGSLTYNDNQQQLKAGDLFFIDCQEYQRYQTISEEPWEM
                     DWIHLNGQNVQSFYQEFTKDGHNTFHSTGDPSENKIHHLITELIHMQQGTNARTDFQS
                     SVAIHELLNELILQKYQLDFEEEDIPAYVYKLKQYLDEHFKETITLDQLEQQFLLNKY
                     QLSKDFSKFIGSPPIDYLISKKLSYAKDLLRYTEFTVRMISEEIGIENFAYFSRLFKA
                     KTGLSPRDFRKFS"
     gene            16028..17488
                     /gene="rhaB"
                     /locus_tag="IXR40_000470"
     CDS             16028..17488
                     /gene="rhaB"
                     /locus_tag="IXR40_000470"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HAQ4360345.1"
                     /translation="MNPTFVAIDIGASSGRLMKSTRDAKGSLILEEVHRFKNGFRNKD
                     GHDRWKIDYLIKEILIGFEKLKQTGIDRLFAGIDTWAVDYCLIDEQGDRINDPIAYRD
                     KRTNGAVEQFSEIYSLDKLYEQTGIQIQPFNTLFQLFAEEKENLAKAHKLLLIPDYLG
                     YVFTGNMVTEKTNASTMQLLNAGTKEWEIELLEKIGVSKELFPPLTEPGTILGDLQKE
                     QFSKYDLPDVTFITVASHDTASAVLGTPGQGERWGYISSGTWSLLGIETKIANVSRNA
                     FSENYTNEWGAHNTVRFLKNIMGMWLIQEVARMQEYEYSYAELAELAAKEKPLQQVME
                     INDPRFLNPPNMIEEIQQYCFETEQPVPVSSGAIARCVYDNLAICYAQELIKVEHLTG
                     TKLEKLHIVGGGSNNRLLNQLTADYAGIIVEAGPSEATAIGNVAMQMLSTGQFSNIEQ
                     ARNVIKQSFPCETFYPDENKQNTMEWYVNKIKGVIV"
     gene            17485..18741
                     /gene="rhaA"
                     /locus_tag="IXR40_000471"
     CDS             17485..18741
                     /gene="rhaA"
                     /locus_tag="IXR40_000471"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HAQ4360346.1"
                     /translation="MNTIERNYEQAKEKYATIGVDTDAVLEKIQDIKISMHCWQGDDV
                     KGFLTPDGELTGGIMATGNFPGAARTPEELRQDLEKAYSLIPGKHKLNLHAIYLDTEE
                     SVDLNEIEPKHFEKWVEWAKKEEIGLDFNPTFFSHPMMKDGFTLAHPDKEVREYWIEH
                     GKRSRKIAEYFGKETGQTSINNFWVPDGMKDNPIDRFTPRERLMESLDEIFTEELDER
                     YVQDAVESKLFGLGAEAYTVGSHEFYMGYGLTRDKLVCLDAGHFHPTEVISNKLSSLA
                     LFSKGIMLHVSRPVRWDSDHVVLMDDELQEIAKELVRNELLEKTNIGLDFFDATINRI
                     AAWVIGTRNTQKALLKAMLEPVERLKEMELAFDFTSRMAYTEELKDFPYADVWNYFCY
                     KNQVPVGLDWLEEVQEYQKDVLELRK"
     gene            18755..19600
                     /gene="rhaD"
                     /locus_tag="IXR40_000472"
     CDS             18755..19600
                     /gene="rhaD"
                     /locus_tag="IXR40_000472"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HAQ4360347.1"
                     /translation="MKKIDILQAPYVKEMIETTSNLYRLGWDERNGGNISYLLKEEEI
                     TPFLDPEKVIRRISMIFDASRLAGCYFIVTGSGRYFKNVASEPAENLGIVRVAEDGKT
                     LELLWGLENECLPTSELPSHFMSHIARLEVDPDNRIVMHCHASHLLAMSFTHELDERS
                     FSRTLWQMCTECLVVFPEGISIIPWMVPGTNEIGEATAEKMKETRLVLWPQHGIYGSG
                     KDMDEVFGLIETAEKAAEVYTYVKAQGPILQTITDENLWHLADAFGVTPKAGYLEEVH
                     TKAGV"
     gene            19602..19913
                     /gene="rhaM"
                     /locus_tag="IXR40_000473"
     CDS             19602..19913
                     /gene="rhaM"
                     /locus_tag="IXR40_000473"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HAQ4360348.1"
                     /translation="MVKKAFCMKVYPEKQEEYKKRHDELWPEMRTALREHGVIDYSIY
                     LDPSTSLLFGYLVIEDEKLWEKMANTSINQKWWKYMEDIMETNPDASPVSWELMPVFE
                     L"
     gene            19995..21146
                     /gene="fucO"
                     /locus_tag="IXR40_000474"
     CDS             19995..21146
                     /gene="fucO"
                     /locus_tag="IXR40_000474"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HAQ4360349.1"
                     /translation="MSNRMILNETSYFGKGAIESIVPEFQQRGFGKAAVITDKGLIEH
                     GIATKVTELLDKAAIAYALYDGIVPNPTIQNVKDGVAFVKEAEADCLIAIGGGSPIDT
                     AKAIGIILTNPEFSDVISLEGVADTKNPCLPILAIPTTSGTAAEVTINYVITDEVNHR
                     KFVCVDPHDIPIVAFIDSDMMMGMPKKLAASTGMDAMTHAIEGFITKGAWEMTDMLHL
                     KAIEIIGHSLEVSVDGDQNGREKMALGQYIAGMGFSNVGLGLVHGMAHPLSAWYNIPH
                     GVACAALLPTVMKYNKEYTGEKYREIALVLGIKGAAEMSLEDVREAACGEIDRLSKAV
                     GIPETISELGVKEADIPAIAEDALRDVCTPGNPRETTVEEIIALYQSLM"
     gene            21273..22031
                     /locus_tag="IXR40_000475"
     CDS             21273..22031
                     /locus_tag="IXR40_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HAQ4360350.1"
                     /translation="MENKKPYGTVLIKASKILDYLAENQDVSLQTIAKGVGMTSSTVL
                     KILDTLLMIGYVNKNSEKNYRLGAKLIRYANKNIEQIDLVELTLPFLEQLQQKIDETI
                     HLGVLDNNEILYVNKLDPKHQTIRMSSKIGITRPLYNSAMGKAVLAEFSEEQYTDYLE
                     KHPLIPYTEYTITNALRLKKEIQTVKETHIAFDDEEIERDIFCIGASIVKNEQIIGAF
                     SVSMPKYRLTDETKEQIISALKQTKSEIEQRIQK"
     gene            22131..22775
                     /locus_tag="IXR40_000476"
     CDS             22131..22775
                     /locus_tag="IXR40_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HAQ4360351.1"
                     /translation="MKKIDILSRLKNAGVIAVVRGKSKEEALNACHAIIKGGLTGIEL
                     TFTVPQADQVIKELLSFYKDQPEIVIGAGTVLDAVTARLAILAGAEYIVSPSFDQETA
                     EMCNLYQIPYLPGCMTITEIKTALKSGVDIVKLFPGSAYGPSIISAFKAPMPQVNIMP
                     TGGVSLDNMKEWFDAGVVTVGVGGNLLAPAATGDFDKVTEVAQQYAAKMKEIKR"
     gene            22782..23789
                     /locus_tag="IXR40_000477"
     CDS             22782..23789
                     /locus_tag="IXR40_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HAQ4360352.1"
                     /translation="MGKVVTLGEIMLRLSTEQGTRIDSSERFAAHYGGGEANVAISLA
                     NYGHEAIFATKVPDNALGKAVKKHLQCYGVDTKQVLSGGSRLGTYYMETGSGERAASV
                     IYDRAGSSFAEMDHLEWSLEELFQGIDIFHVSGITPALSKKWQKMTKQVIEAAKKAGC
                     LISFDINYRGKLWTQQEASEVIHQLLPLVDICSAGKMDALYLLGIEKAPEAEEQPLIY
                     YYQKMQEKFPNIQVFYSTKRTVHSASENELKGTLWMNHEYVESQVHRITPIVDRVGGG
                     DAFAGGVLHGILSNMSPQEIIDFATAASALKHTIHGDCNQFSQEEVAQFLACGSGKII
                     R"
     gene            23805..24647
                     /gene="kduI"
                     /locus_tag="IXR40_000478"
     CDS             23805..24647
                     /gene="kduI"
                     /locus_tag="IXR40_000478"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HAQ4360353.1"
                     /translation="MQEMETRYTHSPEDIRHYSTEQLRKEFLVEKVFEPGKISLTYTH
                     NDRMIFGGVTPTEKELEITLDKELGVDYFLERRELGVINIGGPGFIEIDGQKEEMKKQ
                     DGYYIGKETRHVVFSSQDAENPAKFYISSVPAHHKYPNVKISIDQVKPMETGEGLTLN
                     ERKIYQYIHPNVCESCQLQMGYTILEPGSAWNTMPCHTHERRMEAYVYFDYANEDTRV
                     FHMMGKPDETKHLVVDNEQAIISPSWSIHSGVGTSNYSFIWAMCGENITYTDMDMVQM
                     DQLK"
     gene            24667..25470
                     /locus_tag="IXR40_000479"
     CDS             24667..25470
                     /locus_tag="IXR40_000479"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HAQ4360354.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIPDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(25719..26783)
                     /locus_tag="IXR40_000480"
     CDS             complement(25719..26783)
                     /locus_tag="IXR40_000480"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HAQ4360355.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKVPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAKEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(26780..27865)
                     /locus_tag="IXR40_000481"
     CDS             complement(26780..27865)
                     /locus_tag="IXR40_000481"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HAQ4360356.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            complement(27878..28855)
                     /gene="mvaD"
                     /locus_tag="IXR40_000482"
     CDS             complement(27878..28855)
                     /gene="mvaD"
                     /locus_tag="IXR40_000482"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HAQ4360357.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKQGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            complement(28848..29792)
                     /gene="mvk"
                     /locus_tag="IXR40_000483"
     CDS             complement(28848..29792)
                     /gene="mvk"
                     /locus_tag="IXR40_000483"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HAQ4360358.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            30114..30767
                     /locus_tag="IXR40_000484"
     CDS             30114..30767
                     /locus_tag="IXR40_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HAQ4360359.1"
                     /translation="MIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFYAN
                     PEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEVRV
                     YDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYDYY
                     KELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVAI"
     gene            30852..31757
                     /locus_tag="IXR40_000485"
     CDS             30852..31757
                     /locus_tag="IXR40_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HAQ4360360.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWGIALIISLVLSIWMLIALWRRIR"
     gene            complement(31759..32391)
                     /locus_tag="IXR40_000486"
     CDS             complement(31759..32391)
                     /locus_tag="IXR40_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HAQ4360361.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGDQSYLDAKN
                     MVLRESHIQKLTMQKTVLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTAIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     gene            32711..33235
                     /gene="infC"
                     /locus_tag="IXR40_000487"
     CDS             32711..33235
                     /gene="infC"
                     /locus_tag="IXR40_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HAQ4360362.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     gene            33307..33507
                     /gene="rpmI"
                     /locus_tag="IXR40_000488"
     CDS             33307..33507
                     /gene="rpmI"
                     /locus_tag="IXR40_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HAQ4360363.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            33560..33919
                     /gene="rplT"
                     /locus_tag="IXR40_000489"
     CDS             33560..33919
                     /gene="rplT"
                     /locus_tag="IXR40_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HAQ4360364.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            34171..35508
                     /locus_tag="IXR40_000490"
     CDS             34171..35508
                     /locus_tag="IXR40_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HAQ4360365.1"
                     /translation="MSDIIIGILLVISFFFMVWYCVKGYNLMVGFAIMATVWMGLALV
                     GNTFSPNPAMEGQGVIDVLTHIYTTGPAEYAKSILVNVFFGAFFGRVLVDSGIAATLI
                     RKVVELGGDKPRITMSLLCIVTAVIFMSMTGIGPVISIAVIVLPILMSLGISVPVALF
                     SFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTYNDYFQIGMIGMIVSLVVVLTVA
                     NISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVLGVVLLDLPIILGFILAGIWALL
                     FTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMTLAMFNNSAAYASPYFSAIFGDW
                     IPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILAVVLAVNPTMSPAFLFPLFAITT
                     IAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGWIIGAILCLITFLLYGNA"
     gene            35556..37685
                     /locus_tag="IXR40_000491"
     CDS             35556..37685
                     /locus_tag="IXR40_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HAQ4360366.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLRENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKHLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKSIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPQTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            37660..38349
                     /locus_tag="IXR40_000492"
     CDS             37660..38349
                     /locus_tag="IXR40_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360367.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKKIE
                     KRCTEYDLDYK"
     gene            complement(38757..39370)
                     /locus_tag="IXR40_000493"
                     /pseudo
     CDS             complement(38757..39370)
                     /locus_tag="IXR40_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
     gene            complement(39506..39700)
                     /locus_tag="IXR40_000494"
     CDS             complement(39506..39700)
                     /locus_tag="IXR40_000494"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360368.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            complement(39750..40190)
                     /locus_tag="IXR40_000495"
     CDS             complement(39750..40190)
                     /locus_tag="IXR40_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HAQ4360369.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELDQLFQAYASLDDVNS"
     gene            complement(40194..41039)
                     /locus_tag="IXR40_000496"
     CDS             complement(40194..41039)
                     /locus_tag="IXR40_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HAQ4360370.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVVWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLAANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAIYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            41188..42606
                     /gene="pepV"
                     /locus_tag="IXR40_000497"
     CDS             41188..42606
                     /gene="pepV"
                     /locus_tag="IXR40_000497"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HAQ4360371.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
     gene            complement(42663..43610)
                     /locus_tag="IXR40_000498"
     CDS             complement(42663..43610)
                     /locus_tag="IXR40_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAQ4360372.1"
                     /translation="MEQQEKIAVLIPCYNEEATISTVIADFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAVHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVRNTITRMYKTKILDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMFKDYKPLLFFGIWTIFFFLFGLVTGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYHSRK"
     gene            complement(43833..44183)
                     /locus_tag="IXR40_000499"
     CDS             complement(43833..44183)
                     /locus_tag="IXR40_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAQ4360373.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKSSFLKEGAIEGSWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLEISRKKGATD"
     gene            44383..45462
                     /gene="pepA"
                     /locus_tag="IXR40_000500"
     CDS             44383..45462
                     /gene="pepA"
                     /locus_tag="IXR40_000500"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HAQ4360374.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            45606..45926
                     /locus_tag="IXR40_000501"
     CDS             45606..45926
                     /locus_tag="IXR40_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HAQ4360375.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VTKG"
     gene            45948..46412
                     /locus_tag="IXR40_000502"
     CDS             45948..46412
                     /locus_tag="IXR40_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAQ4360376.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKAVEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKEMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYEIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            46617..47222
                     /locus_tag="IXR40_000503"
     CDS             46617..47222
                     /locus_tag="IXR40_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 domain-containing protein"
                     /protein_id="HAQ4360377.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVDSYGMICSARELHLPNAPAKKGILVLPEDAVVGEAFPK"
     gene            complement(47261..48550)
                     /locus_tag="IXR40_000504"
     CDS             complement(47261..48550)
                     /locus_tag="IXR40_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HAQ4360378.1"
                     /translation="MDRKNVTPKMKKSKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVLMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            48978..49457
                     /gene="rlmH"
                     /locus_tag="IXR40_000505"
     CDS             48978..49457
                     /gene="rlmH"
                     /locus_tag="IXR40_000505"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HAQ4360379.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYALAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            49542..50051
                     /locus_tag="IXR40_000506"
     CDS             49542..50051
                     /locus_tag="IXR40_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1456 family protein"
                     /protein_id="HAQ4360380.1"
                     /translation="MNNNDRLLRLRYAIDLKDTDLIKAFELGGVPLTKEEAQAVLTKV
                     QDKNKDNAENNVYEKTINNQVFDAFLNGLILLARGPQKDKPIVDTPQKSKEIKYINNV
                     LLKKLKIALSMTTDDILDVFAEAEIYPSKGEIGAFLRKEGQRNFKPCGDKYMRNFLKG
                     LGIYNRRKV"
     gene            50151..50801
                     /locus_tag="IXR40_000507"
     CDS             50151..50801
                     /locus_tag="IXR40_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360381.1"
                     /translation="MNDEYKNDEDKMLFEEIENRCRLNFELRGKMSLIQQKKYLANKS
                     EFTLGHVEKLISDWISSRSEFTKIKQPIKFDMKKLLLNKSEIGNRDQYIRAKGQEIID
                     SLGEMRSYNYLYVTHRADGMVITVGKSSSNDIFLDGDLFYQLNTNHLSGTENIILRTE
                     YGNEIFAKYDEILKNYLDWAWIIPVESGDAKKLERLLGDELINKKVPILNYYSHRQ"
     gene            51252..52190
                     /locus_tag="IXR40_000508"
     CDS             51252..52190
                     /locus_tag="IXR40_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015081805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HAQ4360382.1"
                     /translation="MKIAIAGAGAMGSRFGLMLHQSGNEVLLIDGWAEHVQQIKEHGL
                     QANFNGKEVEAKLPIVLQSEVEKEDQVDLIILFTKAMQLEKMLQDIQSLIKKDTEVLC
                     LLNGIGHEDIIEKFVPMENIYIGNTMWTAGLEGPGQVKLFGSGSVELQNLGDGKEAAA
                     KKLADKLSESGLNAHFSDNIHYSIYRKACVNGTMNGLCTILDVNMAELGKTSTAHKMV
                     ATIVNEFAKVAAVEKIELDVPEVIAHCESCFDPETIGLHYPSMYQDLIKNHRLTEIDY
                     INGAISRKGKKYGVATPYCDFLTELVHAKEDSLNVK"
BASE COUNT        16705 a         9413 c        11214 g        14976 t
ORIGIN      
        1 aaaaagccga gctctcgata agctcggctt tcttgtacct cggaaggatt caaataaaca
       61 gaaatgattg taactttcca tcatacatgc aaagcacggt gttgaatttc ttcatgttaa
      121 acaaaaattt tgttttcgtt acatcttcaa catttgaaac atctcttgtt cctattcaat
      181 tttcagacgt ttacgttatt caattgttac gtatcgcatt acttcttgtt tcggatactt
      241 cgtgatccaa acatccatac gcattcacta tttataggtt tgtactctac acgcatgtct
      301 gggtgaaacc tgtacttcta acaactttgt ttgcttacac tgttctatcg agaaattctt
      361 ctgtctattt gatggtatcc tccttcctta catctatata atagcatcct ttggtatcgt
      421 ttgcaaatat aagcacttta aattttacgc tttcttaaca aataatcgat aagcccttta
      481 tttgaagtaa ataaaaaaag gatgttatag taaaataagt accttttttt gtacgaagat
      541 tttaaaggag gaataggatg gaagaataca agcagacaat agaagaagta aagaaggtaa
      601 cagaagcaga tccagatact gggttgtctt cacaagaagt ggatgaacgg cgaaaaaagc
      661 agggattgaa taaattcgat gaggcgccga aagaatcgat gatcaaaaaa ttctttcgaa
      721 gcttgtccga ttttacaacg atcatccttc ttgtagcagc ggtgatttcc ttttataccg
      781 catttgctac agaacatggg gatttatttg aaggactgct gatcatcgct atcgttgtga
      841 tcaactcggt attggcgatt gtccaagaag gaaacgcaga aaaagcactg gaatccttgc
      901 aagatatgaa taaacaaacg gcaactgtca tacgagacgg caaagtgacc actgttgagt
      961 cagagcaact ggtagtgggt gatattcttg ttttagagtc cggtgatgct atttctgccg
     1021 atgcccgttt gatcgaagca tcacaattac gtgtagaaga atcggcgttg actggagaaa
     1081 gtgaagcagt tgaaaaagat gcagcattta ttgctgaaga agatgagtca ttaggtgacc
     1141 aacttaatat ggtatttaaa ggatgtacgg ttgctgcagg tcgtgggaaa gcgatcgtca
     1201 ctgccattgg catggctaca gaaatgggta agatcgcgga tcttttgaac gaaaatacta
     1261 tgcaaaaaac acctttacag gtccgattga atcagctagg caaacgaatc agtatgatcg
     1321 ctttagcggc tgcggcttta gtatttgtga ttggtgaact gcaaggagaa ccactccttg
     1381 agatgttcat gacttcgatt tccttggctg ttgcagctgt accggaaacc ttgactgtta
     1441 ttgttacgtt gacacttgca tacggtgtgc agaagatggc gaggaaacat gcgatcatcc
     1501 gacagttgcc agcagttgaa acgctaggaa ccgctaatgt tatctgctca gacaaaacag
     1561 gaacgctgac acaaaatgaa atgcgcgtcc gccgggtatg gagcaaagaa gatgaagtaa
     1621 cgaatatcga agattcaatg acgaacagcg cgatggaaat attgaaaatg gctgcactat
     1681 gtacagatgt gacggtcgag caagaagatg acgaccttgt tatcaaaggt aatccaacag
     1741 aagtagccat cgtaagggct gttgaagaga attatcatac aaaggcagaa ttagaagaaa
     1801 aatatccacg agtaaacgag cttccttttg attctgaacg aaaaatgatg acaacagttc
     1861 accaaatggg cgaaaaatac atctcaatca ccaaaggagc attcgatgtt cttgctccgc
     1921 gctttagttc aggcgatgta gaacaagcgg cgatcgttaa tgatcgcttt ggtaaacggg
     1981 cactgagagt gattgctgtt ggttatgcta cttatgacga agaaccgcaa gatatttctt
     2041 ctgaagcact ggaaaaagac ttacgtttga ttggtctgat cggaatgatc gatccaccac
     2101 gtccagaaag taaaggagca atcaagcgag cgaaaaaggc tggcatcaaa acagtcatga
     2161 tcactggaga tcatgtggtg actgccagtg ccatagcgaa agaattaggt atcttgaatg
     2221 atccgtcaga agcactttca ggatcagaac tgcatcaatt atcagacgaa gaattagatg
     2281 cgcgtgtcaa agctctctct gtctatgctc gggtaacgcc agaagacaag atccggatcg
     2341 tcaaatcttg gcaacgtacg ggtgcagtcg tagcgatgac tggggatggt gtgaatgatg
     2401 caccagcgtt gaaagcaagt aacgttgggt gtgccatggg gatcacagga acagatgtgg
     2461 cgcaaagtgc cgcagatatg attttgacgg atgacaactt tgcgacgatc gtagacgctg
     2521 tcagtcaagg acgttcggtt tatcagaata ttcgtaaagc tatcaacttt ttgctaagct
     2581 gtaatatttc ggagatcttt attgttttga ttgcgatgct gttaggatgg ggagcaccat
     2641 ttacagctgt gcaactactg tttgtcaatg tagttgctga tggacttcca ggatttgctt
     2701 taggaagaga gccagcggaa cacggcatca tggatcagcc acccattccg aaaaatgaag
     2761 ggatctttgc tcgaggttta ttgcaaaaaa ttgccataaa tgcaggggtc ttcaccatcg
     2821 taaccttgtt tggttattat ttaggtagtt atgtcgatac tatcagccca tgggtagacg
     2881 caagtcagca tgtcggtcaa actgttgcat tcttgatctt agcttattca tcgattctgc
     2941 atgtgttcaa tgtacgcagc agccaatcga tcttcaaagt caatttagcg accaataaag
     3001 ctttggtaga aatggcgtta ctggcattag ctattacaac ggctgttgct ttgctgccat
     3061 ttacgcaaga actattcggc ctagtacaca tcagtttgaa tcactggttc ttggtaggga
     3121 ttttatctat cgtaccaatc gcggtgaatg aactgatcaa gttccatcga ttaccggaag
     3181 cagaagaaga ggaatgatta actgtttcta agttgatttt ctttttactg gaactataca
     3241 aaaaggaggt gtgacatgaa tgttgtcaca cctccttttt gctaatgggc tgaatgtttc
     3301 ttttactgcc tctcgataaa cggtgttctc ctgccacccc ctcggtcaca agtcacactc
     3361 tcttttaaat atcttttggc aattgttcat aaaatgctgc ttttgttgca gaaatgtatg
     3421 ggctgagcca tagataacca ataccagcag ttgctaatgc taagatatgc cagccgataa
     3481 atgaaagatc taaccagaaa agttgtcctt tataaccatc catcaatttt cgacttgcag
     3541 tgatcgtatc cagtacttta ggtgtttgtc ctgtttcttg gacgatatcg tagtaaataa
     3601 aatagctttg agaataagaa tagcttttaa tgattccagg aataactaat agcaaacccc
     3661 ataatgttgt aaagatcgag atcagcacag ctaagctgat cactccgccg ataaacaaac
     3721 ctttgaatcc acgaaatgca tctttgaatg gttcgatctg atctttttgt ccacgtaaaa
     3781 tatcaagata agtccaagaa ataccgctca tgaacaaagc gctaatgatg ctggaaataa
     3841 ttccgccacc gcctcctgaa ctaccgcctc ctgaagttgt cgcttctgag acgctcgctg
     3901 atccatcata tatggtggtg gcaaacaaga taataggaat cataataaga agaatagtag
     3961 caataccaat caatgtaggg attagattta gtaaaacagc ttgtccccaa cgtcctttta
     4021 gactctcttt tgcttggcgt tttaattctg cagaagattg catgattttt ccctcctttt
     4081 ctttaataac accaatatac catgtatcaa aaaatatttc tgtcataatg tttttctttt
     4141 ttttgttatt cataaaaaaa ggataaaaaa aagaatatta aataaagtag aaggaagccg
     4201 agggaacttg caaaaagcac ttgaaacgat tatgatggtg ggagttgtca agatatttta
     4261 tatagaaagt agggaaatga atgacgcaac ctgccattcg ctatcgttta atcaagaaag
     4321 aaaaacatac tggcgcgcgt ttaggggaat tgatcacgcc acacggaact ttccccacac
     4381 caatgttcat gccagtagga acattagcta cagtaaaaac aatgtcccca gaagagttga
     4441 aagaaatggg tgctggcgtt attttaagta atacatatca tttatggcta cgccctggtg
     4501 aagacttagt agaagaagct ggcggactgc ataaatttat gaactgggat caaccgattt
     4561 taacagattc aggcggcttt caagtttttt cattaagtga tatgcggaat atcgaagaag
     4621 aaggcgtgca tttcaaaaat cacttgaacg gttcgcgtat gtttttatca ccagaaaaag
     4681 caatcaacat ccaaaataaa ttgggctctg atatcatgat gagttttgac gaatgtccac
     4741 cattcgatga aagttacgac tacgtgaaaa aatcagtaga acgtacgtct cgatgggcag
     4801 aacgaggatt gaaagctcat gctaatccag accgtcaagg attatttgga atcatccaag
     4861 gagcagggtt tgaagatctt cgtcgtcaaa gcgcgaaaga tctagtcggg atggatttcc
     4921 ctggttactc aatcggcggg ttatctgtcg gggaacctaa atcagaaatg aatcgtgtat
     4981 tagaattcac tacaccgttg atccccgaaa acaaaccacg ttacttgatg ggtgtcggtg
     5041 ctgctgattc attgatcgat ggtgttatcc gtggagtaga catgtttgac tgtgtcttgc
     5101 ctactcgaat cgctcgaaat ggcacatgta tgacttctca aggccgtcta gtagtgaaaa
     5161 atgcgaaata tgcccatgat ttccgtccaa ttgatgagaa atgtgattgt tatacatgta
     5221 aaaactatac acgtgcctat atccgccatt tgatcaaatg tgatgaaaca tttgggattc
     5281 gtttgacttc ttaccacaat ttatacttct tgttgaatct aatgaaacaa gtacgtcaag
     5341 caatcatgga tgataatttg cttgaattta gagaagcctt ttttgaagaa tacgggttca
     5401 ataaagaaaa cgcaaaaagc ttctaaagga aaatctttta aaaattaagt aaaaaactag
     5461 tgttatcagc atttttctgc taaagtgttt tttgtagata cagaattagt gaggtgaaaa
     5521 aaatgggaac attaccaatg cttgtgatgt ttatcgcgct attagcaatg tggtttttta
     5581 tgtcacgttc gcaaaagaaa caacagcaag aacgtcaaaa cttgttagat agcatgaaac
     5641 caggtgattc agtcgtaacg atcggcggat tacatggagt tgtttcagaa atcgacaatg
     5701 acaaacggac agttgtttta gactgcgaag ggatcttcct tgagtacgat cgtgcagcaa
     5761 tcaaaacggt caaaccaggg actgtcgtaa caaatgatgc aacgactact gttgaaacaa
     5821 cagaagaacc agctgagaca gttgaagtaa aaactgaaac aacagaaacg ctggaagaga
     5881 cagaagagaa ggaagaaaaa taagtatcaa agcttattta aagacgaggt agggcagaaa
     5941 gatgtcctac ctcatttttt attcaaaaaa gaaagagata agagcatggg atatattgct
     6001 caatattgaa taatcgggtg tgtcatataa ataataataa ataactttat atatttttct
     6061 atacaaacac ctgtaaataa agcaatttta tatttaaaaa taactgtgaa aaaaatcaca
     6121 aaaaagtgtt tacatagaaa aataaatatt gtatgatata catgtgaatt atttaacaaa
     6181 taaccatgac ccattaggag gataatgatg gctaaagtaa tagaaaaaga aaaaacgaag
     6241 acaattgacg tacaagcaat gattgatgat ttggcagaaa aagcaaatgc agcattgaaa
     6301 gaaatggaaa gctttgatca agaaaaagta gaccatatcg tgcatgaaat ggcaatggca
     6361 gctttggatc aacatatgcc attagcgaag atggctgtag aggaaacagg ccgcggtgtt
     6421 tacgaagata aagcaatcaa aaatatgtat gcgtccgaat atatttggca taatatcaaa
     6481 catgataaaa cagttggtgt gatcaatgaa gatgtccaaa aagggttgat tgaaattgct
     6541 gaaccagtcg gtgtggtttg cggagtaact ccaacaacga atccgacttc cacaacgatt
     6601 ttcaaatcaa tgatcgcgtt gaaaacaaga aatccaatcg tttttgcttt ccatccaagt
     6661 gcccaaaaat cttctgcaga agcagcacga gtggtacgtg atgctgctat cgctgccgga
     6721 gctcctgaaa attgtatcca atggatcgaa catccttcga tcgaagcgac ttctatgcta
     6781 atgaaccatc caggtatcgc gatcgtctta gcgacaggtg gagctggaat ggtcaagtct
     6841 gcttactcta caggaaaacc agctttaggt gtaggtccag gtaacgtacc agcttatatt
     6901 gaaaaaacag caaaaattaa acgtgcagtg aacgatttga tcgtttcgaa aacatttgat
     6961 aatggaatga tttgtgcttc tgaacaagct gtgatcgtgg ataaagaaat ctatgcagca
     7021 gtaaaagcag aattccaagc acaccaagtt tatatcgtaa aaccagatga attgcaaaaa
     7081 ttagaagatg cagtgatgaa cgaaggaaaa tatgcggtca atccatcaat cgttggacat
     7141 tctgcgatgg aaatcgcaaa attggcagga atcagtgtac caaaaggaac gaaaatgctg
     7201 attgctgaat tggaaggcgt aggcccagat tatccgctat caagagaaaa actttctcca
     7261 gttcttgcca tgatcaaagc taacaacacg gaccatgcgt ttgatttgtg tgaaggtatg
     7321 ttgaatcttg gaggattagg acatacagca gttatccatt cagaaaacga agagttgcat
     7381 gtcaaattcg gtcttcgaat gaaagcttgt cgtattttag tgaatacacc atctgcagaa
     7441 ggcggcatcg gtgatatcta taacgaaatg attccgtcat tgactttggg atgcggttct
     7501 tatggtaaga actctgtttc tcgtaacgtc tctgctgtaa acttaatcaa tgtcaaaact
     7561 gtagcgaaac ggagaaataa catgcaatgg ttcaaattac cgccaaaaat cttctttgaa
     7621 aagaactctc tattgtactt agagaaaatg gaaaacgttg aacgtgtcat gatcgtttgt
     7681 gaccctggta tggtccaatt cggttactgc gatacagttc gtgaagtatt ggcacgacgt
     7741 aaaaatgatg tgaagatcga agtcttctca gatgttgaac cgaacccatc gacaaatacc
     7801 gtatacgcag gaacgaaact gatggcagac ttcaagccag atacagtaat cgctcttgga
     7861 ggcggttctg caatggacgc agctaaggga atgtggatgt tctatgaaca cccagacaca
     7921 tctttctttg gtgcaaaaca aaaattcttg gatatccgta aacggacata taagatcgac
     7981 aaaccagaaa aaacacaatt cgtatgtatc ccgacaacat cagggactgg ttctgaagta
     8041 acgccatttg cggtcatcac tgacagtgaa acacatgtga aatatccgtt agcagattat
     8101 gcattgacgc cagatgtcgc aatcgtcgat cctcaattcg tcatgtcagt tccagcatct
     8161 gtcacagcag ataccgggat ggatgtgtta acacatgcaa tcgaatccta tgtttcagtc
     8221 atggcttcag attatacacg tggattgagc ctacaagcaa tcaagttagt ctttgactat
     8281 ttagaaaaat cagtaaaaac acctgatatg gaatcacgtg aaaaaatgca caacgcttct
     8341 acaatggctg gtatggcgtt tgctaacgca ttcctaggta tttgtcactc agtcgcacat
     8401 aaaatcggcg gggaatacgg gatccctcat ggacggacaa atgcgattct tttaccgcat
     8461 attatccgct ataatgcaaa agatccacaa aaacatgcga tgttccctaa atatgactat
     8521 ttccgtgcag atacagatta cgcagatatc gcaaaattct taggtctgaa aggcgaaaca
     8581 acagaggaat tagtcgaagc tttagcaacg gctgtttatg aattaggaaa atctgtcggc
     8641 atcaacatga gtctaaaagc tcaaggagtc acacaagaaa cactagatac aaccgtagac
     8701 cgtatggctg aattagctta cgaagaccaa tgtacgacag ctaatccgaa agaaccattg
     8761 atctctgaat tgaaacagat catcattgat gcttacaacg gataagcaaa agaaagcgta
     8821 gaaaaaagat aagaaaatag atgaaaaaga acttggaaaa cgttgtttct ccaagttctt
     8881 tttttaattt ccaagtaact gaaagttact tttgttattt aacatttagg tcaattttag
     8941 acagtttttg ttcaaaaagc gatatttata gtggacggta ttactgctat attaaggata
     9001 taaaatgaaa gcgtttaaaa aggtggcgta aagatgatta ttaaagaaga gatttttgta
     9061 cctaaagaat tagtgaaaga aaaaattgac ctgctcgttg aaaacctgac aacgatcaaa
     9121 gacgataatg gtgaattttt gttggacttt gatggactga aagtagatga caaaagctgg
     9181 acagtgtgga attggccaca aggtgtcggt ctatatggta tttataaaaa ttaccagatg
     9241 acaaaaaatc ctcgcgctta tcaagtggtc aatgaatggt ttgaggatcg tatggaagaa
     9301 ggcgctccgc ccaaaaacgt caatacaatg gcaccgctat tgactatggc ttacttgtat
     9361 gaagacacga aagattcacg ctatttgcct tatttagaac aatgggcaga atgggtcatg
     9421 aatgacatgc ctcggacaaa tgaagacggg ttacagcatg ccacatatgg accggaaaat
     9481 aagaatcagt tgtgggacga tacattgatg atgacagtgc ttcctttggc aaaaatcggg
     9541 aaactgttga atcgcccaga atatttagaa gaagctcgtt accagtttat gatccatatc
     9601 aaatacttga tggataaacg aacaggattg tggtatcacg gctggacgtt tgaaggaaat
     9661 cataactatg ccgaagcatt ttgggctcgt ggaaactgct ggttgacgat tgctattcca
     9721 gagatcattg aaatcttaga attatcgaaa gaagatgcat tgcgcaaatt attgatcgaa
     9781 acacttgaag cacaagtgcg tgcattaaaa acttatcagt ctgaaagcgg tttatggcat
     9841 acgttgttgg atgatccttc ttcttacgta gaatcttctg caactgcagg atttgcttac
     9901 ggtattttga aagcggtcca taaacgttat ttaccacaag aatataaaga agtcgcttat
     9961 cgtgctatcc aaggattgct tgaacaaatc gatgaaaaag gagaagttca aaacgtttca
    10021 atcgggacag gaatggggga cagtttagat ttttatcgga atatcggaat cacagcaatg
    10081 ccttatggac agtcgttaac ggtgctttgt ttgacagaat tgctcgtctc ttattgttaa
    10141 aagaaaggaa acccatatga aaaaaacatc actgctgttt gcagcaagtt cgcttagcct
    10201 aggtctgcta ggtctaagcg gctgcggaaa taattctagt gtggcaactg tcgcagatgc
    10261 agatgtaaat gagatagtta ccttgcgctt tgcttatgca agcaacagcc agccagtaat
    10321 tgatgcaatg aatgaatttg ggcgtttagt aaaagaaaaa acagatggtt ccgtacagat
    10381 ccagtatttc ccagatggac aactgggtgg agaacgtgaa ctgatcgaat tgacacagtc
    10441 aggagcagta gatttcacaa aagtaagtgc ctcagcgttg gaaagtttct ctaaagatta
    10501 ttcgattttt tcagttcctt atctattcaa tgatgaagaa catttcttta aggtgatgga
    10561 taatgaagaa ataatggagc caatctacca atcgaccaaa aatttaggat ttaccggatt
    10621 gacctattat gattctggtc agcgcagctt ttatatggta gacggtccga tccatacgcc
    10681 ggaagatttg gagggaaaga agatccgtgt gatgcaaagc gaaaccgcta tcaaaatggt
    10741 agagctttta ggcggttcgc ccgtacctat gggaagtgat gaagtgtaca cgtctcttca
    10801 atccaatttg atcaacggat cagaaaacaa tgaatttgtc ttgtatacag ctggacatgg
    10861 tggtgtggct aaatactatt cctatgatga gcatacacgt gtgccagata tcatcatcat
    10921 gaatgatgcc atcaaagaac agctaactga tgagcaggaa aaagccattg aagaagcagc
    10981 gaaagaatca acggtttttg aaattgaagc ttttgcaaaa gcaattgaag aagaaaaagc
    11041 tttagcacaa gaagaacatg gagtccaatt caatgatgta gataatacac cgtttcgaga
    11101 ggcagttgcc ccacttcatg atatattcaa aaacgatcct acctacaaag acctttatca
    11161 aaagatccaa gagcaaggag cgtagctgtg atgaaaatga ttttaaacaa ggtattagag
    11221 atcctgggag ctgttttgct tgttgggatg gtcgctgttg ttttatggca agtattttcc
    11281 agaacggttt taggaaatcc aaatacggtc acggaagagc ttgttcgatt cggtcttgtc
    11341 tggtttgcca tgttgtcttc cgcgtatgtt gtgggacaaa aagcacattt agccgtaacg
    11401 gttttaagtg aaaaattaac tggcaaaaaa agtaaaattt tagaagttgt tgttcaaagt
    11461 ttatttctgg tatttgctgc gatgatcatg gtgtatggcg gatggaatgc tgtcacattg
    11521 acaatggggc agatctcgcc ttctttaagt attcctatgg gatatgttta tctgtcagta
    11581 cctgtatcgg gggtactcat cattatctat agcctgatca atctaatcga tacattaagc
    11641 aacaagccag caattcaaga aaaaatataa aaatggagga ataaaatggc aatagaagcc
    11701 ggattagtgt tattttttgt atttgttgtg ttgcttgtat tagggatgcc gattgctata
    11761 agtattgcat tctcatcgat gatgacttta ttgttagtta taccgtttga tgtttctgct
    11821 tttagttcag ctcaaaaaat ggtgggaagt atcaatagtt tttcgctgat cgctattccg
    11881 tttttcgttc tctcgggcat tatcatgaat aatggaggga tagctaagaa actagtggat
    11941 tttgcgatgt tgttcgtcgg gcgcgtgccg ggggctttgg ctcatacgaa tgtgttaggg
    12001 aatgctttat ttggttccat ctctagctcg gccattgccg cttctaccgc gattggcgga
    12061 gtgttgatcc ctcagcaagt ggaagaagga tatgaccgga agtttgcgac agcggtcaat
    12121 atcgcgtcag ctccgacagg tatggtcatt cctccaagta ctgcttttat catgtattca
    12181 cttgttgctg gtggtgcttc gatctctgct ttgtttatgg gaggttatct cgtaggcgct
    12241 ttgtgggcgc taggaatcat gctagtagca ttcatcgttg ctaaaaagaa taaataccct
    12301 gttgtcgaaa aaggacagat ggctcatgct ggaaaaataa taaaagaggc gattcctagc
    12361 cttctattga ttgtcatcat tatcggtggt atcttgacgg ggatatttac agcagtagaa
    12421 gcttcagcga tagctgtcat ttactccctg ttgattgcta tgttttacta taaaacggta
    12481 aaactaaaag atatacctaa tatgttgttt caatcagtag caatgtcagg gacgatcatg
    12541 ttcttattgg ctacttcttc catgatgtct ttcgccatgg cgtttaccgg tattcctcag
    12601 gcaattagtt cgttgattat gggcgtaacg gataataaat ttattattct gttattagtc
    12661 aatcttgtgt tattactggt gggtatgttt atggatgtgg cgcctgctat cttgattttt
    12721 acaccaatat ttttaccaat cgtcacaagt gtaggggttg atcctgtaca ttacgggttg
    12781 ttttcaatca tgaatctgtg tgtaggctcc atcacgccgc cagtaggtac aggactatat
    12841 gtcggtgcaa gtgtaggagg cgtaaaagca gaggcaatgc tgaaaccgct tcttcctttt
    12901 tatggggtta tcttagtcgt cttgtttttg attacttact tcccgcaaat cgtcatgtgg
    12961 ctacccaata tgctgagtta ggagaatagt tatgttgaac attacaatta gaggacatga
    13021 tctttccgaa gtccaaacga tagaagatct tgcagaaaaa acaaaagaac aagggattca
    13081 tacactgcag ctcgccttag gtctttcgtt tcctgaaaca ccttctggcg caaatgagat
    13141 caattctggg atgggaaatt atgtcaaacg agttttagaa aagcaagaag tgaccgtagg
    13201 aattttaagt tgctatatca atatgattca tccagattta acgatacgac aagagttgct
    13261 gacaaagttc gagcagtatc ttcgctatgc ttcttccttt ggtgcgtcga tggttgcttc
    13321 ggaaactgga tgtgttttgc cggaaatcca atatacggaa gaaaatttca cagatgaagc
    13381 atttgctgaa gctgtgtccg ttatccgtcg cttggtaaaa gctggagaaa aataccaaat
    13441 gatggtgggg atagaaccag gtttgaatca tccggtgtat tctttagcaa gggtagagca
    13501 gctgatccaa gcagtagatt cggactatct aggaatcatt ttagatccga ccaatttgat
    13561 cacaagtagt gattatcaag aacaagtcca attggtagaa gaagcttttg aacgttttgg
    13621 tgaaaagata tgtgcggttc atttgaaaga ttttcgtgtc gaacaggaaa aaatcgtgcc
    13681 ggtaaatttg ggagacggtg tgatcgagta cacaaaaatc aaagaaatca tcatgaagaa
    13741 tcgtccgtac ctgtatgtgg ttcttgaaga aacaaaagat gatgggattc gttatggaag
    13801 aagtcttctt gaataatgta aagaagacgt tggttaacta atatttagaa tggagggggc
    13861 ggggctagaa gatgccacgt ctcttctttt ttataagagt atataaaagc agctcttttt
    13921 gattacaaaa aacgtggtat aataaaattg tgcataagtg aacaaaagga ggtgcggcac
    13981 atgctccaaa agaaaatcag cggtgaacaa gtcaatacga tggtttctga tcagtatgaa
    14041 atctatcatg tcaaagatgt cgtcagccaa aataaaacga tctatcatca tcatgatttc
    14101 tatgagatcc atgctacatt aaagggagaa gcgacttttt atttgaacgg acgacaattt
    14161 acgatcaaag caggaagtgt gctgctcatc cattccaatg atttgcatcg tatcgtccgc
    14221 caatcttcag atgtattcga gcgtgtctat atctttgtca ccccttcttt tctagaaagt
    14281 cgttccacgc catggtctaa tctatcggct tgttttcaac caatgggaga gaagaggagt
    14341 cgtgtattgc aaatagaaca ggaagtattg aagcaaaaat tatcatttat cgaccatcct
    14401 cctgataaaa aaatttacgg tgaagacata aaatatgaac aagctctggt agaatacttg
    14461 atttttctca atcaagttgt acaaaaagaa gagagtgcgc aagaacagaa tgctgtagtt
    14521 cctaatgagc gtgtggaaca aatgttacaa tatatctcaa aaaatttatc tcatccgctt
    14581 tctttagagg aaatggaaaa gcagtttttt gtcagcaaat accatatcac acgagaattt
    14641 aaaaagtaca ctggatttac gtttcatcag tatgtaatga agaaaaagct gatctatgcc
    14701 aagcacttgt tgcgagaata ccgcagctct agtgctgtat atagtaaaag tggtttttct
    14761 tcttatccgc attttctgaa agcattcaag agagagttcg gcataacgcc taaagaattt
    14821 ttgaaacgtg atacacagaa acagttggtt cattatgaac attttgaaga tgaacaatga
    14881 gaatgatcac taaaaaataa ccgcagtagc tgctgttgtt tacatagaag cagaaactgc
    14941 ggttatttta tttttatcta tatatttcaa aatattttga aaaaatgacg tacatattat
    15001 atgaatcagc tgaatttacg aaagtctctc ggcgatagtc ctgtttttgc tttgaacagg
    15061 cggctaaagt aagcaaaatt ctcaatccct atttcttcgg aaatcattcg aaccgtaaat
    15121 tctgtatacc gaagaaggtc tttagcgtaa gaaagttttt tgctgatcaa ataatcgatt
    15181 ggtggagaac cgataaattt ggaaaaatct ttgctcagct gatatttatt caataagaat
    15241 tgttgttcta attgatcaag tgtaatcgtt tctttgaaat gttcgtctaa gtattgcttc
    15301 agtttgtaaa cgtaggcggg aatatcctct tcttcgaaat ctagctgata cttttgcaaa
    15361 atcagttcat tcagcaactc gtggatagct acagaggact ggaaatcggt acgggcattc
    15421 gtgccttgtt gcatgtggat caattctgtg atcaaatggt ggatcttgtt ttctgatgga
    15481 tcccctgttg aatggaaggt gttatggccg tcttttgtga actcctgata aaatgattgg
    15541 acgttctgac cattcaaatg gatccaatcc atttcccatg gttcttcgct gatcgtttga
    15601 taacgctgat attcttggca gtcaataaaa aataagtctc cagcttttag ctgttgctga
    15661 ttatcattat atgtaagcga acctttgcca gacaaagtaa actttatcaa gtaagaaggt
    15721 aaatgtgctc gttcagtata gtaagggatt ggtgctttga agtaaccgat ttcttggata
    15781 taaaaaaata aattcctgct tctttgtgta ggcgtcaaga tcactctttt tgagtcttcc
    15841 gaccatgagt ggttggcttt ttcccagtaa tccatgtaaa cactcccaac ttgtcaagat
    15901 aatgcaatta tataccaaaa tagtgtgaag caaaatataa gattctgtat tatgatagca
    15961 ttgttaataa atgataacgc tttattaata aagtgctaat caacaataaa gtaaaagagg
    16021 tggagaaatg aatccaacat ttgttgccat cgatatcggt gcatcaagcg gacgactaat
    16081 gaaaagtacg agggatgcaa aaggttcttt gatcttggaa gaagtacacc ggttcaaaaa
    16141 cggctttcgg aacaaagacg gtcacgatcg ctggaagatc gattatctta tcaaagagat
    16201 tttgattgga tttgaaaaat taaagcagac agggattgat cgcctttttg cggggatcga
    16261 tacatgggca gtcgattact gtctgattga tgaacaaggg gatcggataa atgatccgat
    16321 tgcttatcgg gacaagcgta ccaatggagc agtagaacag ttttctgaaa tctattctct
    16381 agataagttg tatgagcaga cagggattca gatccagcct ttcaatacct tgttccaatt
    16441 gtttgctgaa gaaaaagaaa atttggcaaa agcacataaa ttgttactga tacctgatta
    16501 tttagggtat gtctttactg gtaacatggt gacggagaaa actaatgcat ctactatgca
    16561 gctgctgaat gcagggacaa aagaatggga aatagaactt cttgaaaaaa tcggtgtctc
    16621 gaaggaatta tttccaccat tgacagagcc gggaacgata ctaggagatc tgcaaaaaga
    16681 acaattttca aaatatgatt tgccagatgt gacctttatc acagtagcaa gtcatgatac
    16741 ggcgtcagct gtattaggaa cgccaggtca aggagaacgt tggggttata tcagcagtgg
    16801 gacatggtcg cttttaggga ttgaaacaaa gatcgccaat gtttctcgca atgctttttc
    16861 tgaaaattat acgaatgaat ggggtgccca taacacggtg cgttttttga aaaacatcat
    16921 ggggatgtgg ttgatccagg aagttgcccg aatgcaagag tacgagtaca gttatgcgga
    16981 attggcagag cttgctgcaa aagaaaaacc gctgcagcaa gtgatggaaa tcaatgaccc
    17041 tcgatttttg aatcccccaa atatgataga agagattcag caatactgtt ttgaaacaga
    17101 gcagccagtc cctgtctcat cgggagctat cgctcgttgt gtgtatgata atcttgctat
    17161 ttgttacgca caagagctga tcaaagtaga acacttaact ggaacgaaat tggaaaagct
    17221 gcacatcgta gggggcggat cgaataatcg tctactgaat caattgacag cagattatgc
    17281 cggaatcatt gtagaagcag gacctagtga agccacagca atcgggaatg ttgccatgca
    17341 aatgctcagt acaggtcagt tttcgaatat agaacaagca agaaatgtaa tcaaacagtc
    17401 gtttccatgt gaaacttttt acccagatga aaataagcaa aacacgatgg aatggtacgt
    17461 gaataaaatc aaaggagtaa tcgtatgaac acgattgaaa gaaattacga acaagcaaaa
    17521 gaaaaatatg caactatcgg tgtagataca gatgctgtac tagaaaagat acaggacatc
    17581 aaaatttcta tgcattgctg gcaaggagat gatgtcaaag gtttcttgac accggatggc
    17641 gaattgaccg gtggaatcat ggcgacaggg aattttccag gagccgcacg aacacctgaa
    17701 gagcttagac aagatctgga gaaggcttat tcgttgatac cgggcaaaca caaattgaac
    17761 cttcatgcta tctatttgga tacagaagaa tctgtcgatc taaatgaaat tgagccgaaa
    17821 cattttgaaa aatgggtaga gtgggcaaaa aaagaagaaa tcggtcttga cttcaatccg
    17881 actttctttt cgcatccaat gatgaaagac ggctttacat tggctcatcc agataaagaa
    17941 gttcgtgaat actggatcga acacgggaaa agaagccgca aaatcgcgga gtactttggg
    18001 aaagaaactg ggcaaacaag tatcaataac ttttgggtac ctgatgggat gaaagataat
    18061 ccgattgatc gttttacccc acgggaacgt ttaatggaat cactcgatga aatttttaca
    18121 gaagagttag atgaacggta tgtacaagat gcagtagaaa gcaaactatt tggtttaggc
    18181 gctgaagctt atacagtcgg ttcccatgaa ttttatatgg gttacgggtt gactcgtgac
    18241 aaacttgttt gtctagatgc tggacatttt catccaacag aagtgatttc caataaatta
    18301 tcttcattag ctttattcag caaaggaatc atgttgcatg tttcccgtcc agtgcgttgg
    18361 gattcagacc atgtggtttt gatggatgat gaattgcagg aaatcgctaa agaattagtc
    18421 cgtaacgaat tgttggaaaa aacaaatatc ggtctggatt tctttgatgc aacgatcaac
    18481 cgtatcgctg cttgggtcat cggtacgaga aatacacaaa aagcactgct gaaagctatg
    18541 ctggaaccag ttgagcgatt gaaagaaatg gagctggctt ttgactttac ttcaagaatg
    18601 gcttatacgg aagaattgaa agatttcccg tatgccgatg tatggaatta tttctgttac
    18661 aaaaatcaag ttccagttgg tttggattgg ctggaagaag tccaggaata tcaaaaagac
    18721 gtgttggaat taagaaaata ggagtgtggc tatattgaaa aaaatagata ttttacaagc
    18781 gccttatgtg aaagaaatga tcgaaacgac gtcgaatctt tatcgcttgg gatgggatga
    18841 aagaaatggc gggaatattt cttatttact aaaagaagaa gagatcacac cgttcttgga
    18901 tcctgaaaaa gtgatccgcc gcatctcgat gatttttgat gccagccgtt tagcaggatg
    18961 ctattttatt gtaactggtt caggaagata ttttaaaaat gtagcgagcg aacctgccga
    19021 gaatcttgga atcgttcgag ttgctgaaga tggcaaaaca ctggaacttt tgtgggggct
    19081 ggaaaacgaa tgccttccta caagcgagtt gccaagtcat ttcatgagtc atatcgcccg
    19141 tttagaagta gacccagata atcggatcgt tatgcattgc catgctagtc atctattagc
    19201 gatgagtttt acgcatgaat tagacgaacg ttcctttagt cgtacgctat ggcaaatgtg
    19261 tacggaatgc ttagttgttt ttccagaagg aatttccatc attccgtgga tggttccggg
    19321 aacaaatgag attggggaag caacagctga aaaaatgaaa gaaactcgat tggttttatg
    19381 gccacaacat ggaatctacg ggtcaggaaa agacatggat gaagtctttg gtttgatcga
    19441 gacagcagaa aaggcagcag aagtctatac gtacgtcaaa gcgcaaggac caatcttgca
    19501 aacaatcacg gacgaaaacc tgtggcattt agcagatgcg tttggtgtca ctccaaaagc
    19561 aggttatttg gaggaagttc atacgaaagc aggtgtctga catggtgaaa aaagcttttt
    19621 gcatgaaagt ttacccagaa aaacaagaag aatacaaaaa aagacatgat gaactttggc
    19681 cagaaatgcg tacagcactt cgtgaacacg gggtcatcga ctattcgatc tatcttgatc
    19741 cgagtacaag tttgttattt ggttacttag tgatcgaaga tgaaaagtta tgggaaaaaa
    19801 tggcaaatac atctatcaat caaaaatggt ggaagtacat ggaagatatc atggagacaa
    19861 atccagatgc ctctccagtc agttgggaat tgatgccagt ctttgaactg tagcaacaag
    19921 caactgggca accggttgct tggggttctt tcgtttttat tgtgaaaaaa aatacaaatt
    19981 aggaggaata gaaaatgagt aatcgaatga ttttaaatga aacatcgtat tttggaaaag
    20041 gagcgattga gtcgatcgtc cctgaatttc agcagcgagg attcggcaaa gcagctgtca
    20101 ttactgacaa aggattgatc gagcacggta tagcaacaaa agtaacagaa cttctagata
    20161 aagcagcaat cgcttatgct ttatacgacg ggatcgtacc taatccaacg atccaaaatg
    20221 taaaagatgg agtggctttt gttaaagagg cagaggcaga ctgtttgatc gcaatcggtg
    20281 gaggttcgcc aatcgatacg gcaaaagcca ttgggattat tttgacgaat ccagagtttt
    20341 cagacgtcat tagtttagaa ggtgttgctg atacgaaaaa tccatgttta cctatattag
    20401 ctataccaac gacttctgga acagcagcag aagtaacgat caactacgtc atcacagatg
    20461 aagtaaatca ccgaaaattt gtttgtgttg atcctcatga tatcccaatc gtcgcgttca
    20521 tcgacagcga tatgatgatg ggaatgccga aaaaattggc tgcatcaaca ggtatggatg
    20581 ctatgacgca tgctattgaa gggtttatca caaaaggcgc ttgggaaatg actgatatgc
    20641 tgcatttaaa agcaatcgaa atcatcggcc attctttgga agtttctgta gatggcgatc
    20701 aaaatgggcg agaaaaaatg gcattaggac agtatattgc gggaatgggc ttctcaaatg
    20761 tcggtttagg actggtacac gggatggctc acccgttaag tgcatggtac aacattcctc
    20821 atggcgtagc gtgtgcagca cttttgccaa ctgtcatgaa atataacaaa gaatatactg
    20881 gagaaaagta ccgtgagatc gctcttgttc tagggattaa aggagcagct gaaatgtctt
    20941 tagaagatgt aagagaagcg gcttgtggtg agatcgatcg gttgagcaaa gcggttggaa
    21001 tcccagaaac catttctgaa ttaggtgtaa aagaagcaga tattccagca attgcagaag
    21061 atgctttgcg agatgtatgc acaccaggaa atccaagaga aacgacagta gaagaaatca
    21121 ttgctttata tcaaagtttg atgtaaaaac gaagcggatc ttcaacatta aattgcctgt
    21181 aaagagaaat ggtagtttat atctggatat ctcttttaaa ttgatggtat ttccgctata
    21241 atttttctta taaagaaata ggagaatatt atatggaaaa taaaaagcct tatggaactg
    21301 tattgatcaa agcctctaaa atactagact atttagcgga aaaccaagat gtctctttgc
    21361 agacgatcgc aaagggtgtg ggaatgacct cttctacagt cttgaaaata ctagatactt
    21421 tgttgatgat cggctacgta aataaaaatt cagagaaaaa ctatcgttta ggtgcaaagc
    21481 ttattcgcta cgcgaataaa aacattgaac aaatcgattt ggtagagttg actttaccgt
    21541 ttttagaaca gctgcagcaa aagatcgatg agactatcca cttaggggta ttggacaaca
    21601 atgagatctt gtacgtgaac aaactagatc caaaacatca aacgatccgc atgtcttcaa
    21661 aaatcggaat cacccgacca ttatacaatt ctgcgatggg caaagccgta ttagcagaat
    21721 tcagtgaaga gcagtacact gattatcttg aaaagcatcc gttgatccct tacacagaat
    21781 atacgatcac caatgcatta cggttgaaaa aggaaatcca aacggtaaaa gaaacccaca
    21841 tcgcatttga cgatgaagaa atcgaacgtg atattttttg tataggagcc tcaatcgtga
    21901 aaaacgaaca aatcattggt gcatttagtg taagtatgcc gaaatatcgt ttaacagatg
    21961 agacaaaaga acaaataatc agtgccctca agcaaacaaa aagcgaaatc gagcaaagaa
    22021 ttcaaaaata atgaaaaaag cgtttgcaat ttttcttttc tgccgtataa tatgggtata
    22081 gatttccaag ttataaaata aaatttctaa ataggaaata ggtggagaag atgaaaaaaa
    22141 ttgatatttt atctcgattg aaaaacgccg gagtgattgc ggtggtacgc ggaaaaagca
    22201 aagaagaagc tttgaatgct tgccacgcaa tcatcaaagg tggtctaact ggtattgagt
    22261 tgacttttac agtccctcaa gcagatcaag taatcaaaga acttttgtca ttctacaaag
    22321 accaaccaga aatagtgatt ggcgcaggca cagtattaga cgctgtcaca gctcgcttgg
    22381 ctatcttagc tggcgcagag tatattgtta gcccttcctt tgatcaagaa acggcagaga
    22441 tgtgcaatct gtatcaaatt ccttacttac caggatgtat gactattacc gagatcaaaa
    22501 cagcgctgaa aagcggggta gatatcgtca aactatttcc tggaagcgct tatggaccaa
    22561 gtatcatttc tgccttcaag gcgccgatgc ctcaagtcaa tatcatgcca actggcggtg
    22621 tgagtctgga caatatgaaa gagtggttcg atgctggtgt cgtaacagtc ggagtaggtg
    22681 ggaacctttt agcacccgca gctacaggag attttgacaa agtaacggaa gtcgcgcaac
    22741 agtatgcagc aaaaatgaaa gaaatcaaga ggtagctgct tatgggaaaa gtagtgacac
    22801 tcggagaaat catgttgcga ttgtccacag agcagggaac ccgtatcgat tcaagtgaac
    22861 gattcgctgc ccattatggc ggaggggaag caaacgtagc aatttcttta gctaattacg
    22921 gacatgaagc gatttttgct acaaaagtac ctgataacgc attgggaaaa gcagtcaaaa
    22981 agcacttgca atgttatgga gtagatacga aacaggtatt atctggtgga tcaagactag
    23041 gtacttatta tatggaaact ggtagtggcg aacgcgccgc ctcagtgatc tatgatcgtg
    23101 ccggatcaag ttttgctgaa atggatcatt tggaatggtc gctagaggag ttattccaag
    23161 gaatagatat atttcatgtt tcaggaatca ccccagcttt gtctaaaaaa tggcaaaaaa
    23221 tgacgaaaca ggtgatagaa gctgcaaaaa aagctggctg cctgatcagc ttcgatatca
    23281 actatcgtgg aaaattatgg acacagcaag aagccagcga agtaatccat cagcttttac
    23341 ctttagtaga tatctgctca gctggaaaaa tggatgctct ttatttgtta ggtatcgaga
    23401 aagcgccaga agcagaagaa caacctctaa tttattatta tcaaaaaatg caggaaaagt
    23461 tcccgaatat tcaggtgttt tattcgacca agcgtaccgt tcattcagca agtgaaaatg
    23521 aattgaaggg gacattgtgg atgaaccatg aatatgtgga atcccaagtc catagaatca
    23581 ccccaatcgt ggatcgagta ggtggcggag atgcttttgc aggtggcgtg ctccatggga
    23641 ttttatccaa tatgtctccg caagaaatca ttgattttgc tacggcagct tctgccttga
    23701 agcatacgat ccatggggac tgcaaccaat ttagtcaaga agaagtcgca caatttttag
    23761 catgcggctc tggaaaaatc attcgataga aggagtagaa gaaaatgcaa gaaatggaaa
    23821 cacgttatac acacagtcca gaagatatcc gtcattattc aacggaacaa ttgagaaaag
    23881 aatttttagt agaaaaggta tttgaaccag ggaaaatcag tttgacttat acgcacaacg
    23941 atcgaatgat ctttggtgga gtgacaccta ctgaaaaaga attagaaatc acattagaca
    24001 aagaactagg tgttgattac ttcttagagc gtcgtgaact aggtgtgatc aatatcggtg
    24061 gaccaggatt catcgagatc gatgggcaaa aagaagaaat gaaaaaacaa gacggatact
    24121 atatcggaaa agaaacacga catgttgtat tttcttctca agatgctgaa aacccagcta
    24181 aattctatat tagttctgtt ccagctcatc ataaatatcc aaatgtaaaa atcagtatcg
    24241 accaagtaaa accaatggag actggtgaag gcctgacact gaatgaacgt aaaatctacc
    24301 aatacatcca tccaaatgta tgcgaaagct gtcaattaca aatgggttat acgattttag
    24361 aaccaggaag cgcttggaat acgatgcctt gtcatacaca tgaacgtcgt atggaagctt
    24421 atgtctactt tgattatgcc aatgaagata cacgtgtgtt ccacatgatg ggcaaaccag
    24481 atgaaacaaa acatttagtt gtagacaatg aacaagccat tatttcgcca agctggtcga
    24541 tccattcagg tgtaggtaca agcaattact cattcatctg ggcaatgtgc ggagaaaata
    24601 tcacctatac agacatggat atggtgcaaa tggatcaatt aaaataagca taagggagag
    24661 aaaatgatgg aatttagtat ggatatgttt cgtttagatg gaaaagtagc attagtcacc
    24721 ggtgctgtct atggtattgg atttgagatt gcacgctctt tagctacagc aggagcaaaa
    24781 atcgtattta ataacttgaa tcaagaatca gttgatgaag gtatagcgca ttataaagaa
    24841 gcaggcatcg atgcaaaagg ttatgtctgc gatgtgaccg atgaagaagc ggttcaagcg
    24901 atggttcaac agatcaaaga agatgtaggt tcagttgata ttctagtcaa caatgcaggg
    24961 atcatcaaac ggacaccgat gatcgaaatg gatgcggcag acttccgcca agtaatcgac
    25021 gtggatttaa atgccccatt catcgtttca aaagcagtta ttccggatat gatcgaaaaa
    25081 ggcggcggta aaatcatcaa tatctgctcc atgatgagtg aattaggacg cgaaacggtc
    25141 agtgcttatg ctgcggcaaa aggcggatta aaaatgctga cgaaaaacat cgcttctgaa
    25201 tacggtcaat acaatatcca atgtaatgga attggaccag gttatattgc tacaccgcaa
    25261 actgctccat tacgcgaaac acaagaaaac ggtgaacgtc atccattcga tcaatttatc
    25321 gttggacgta cgccagcagc acgctggggc gagccaatcg atttggctgg accatctgtc
    25381 ttcttggctt ctagcgcatc tgatttcgtt aacggccatg tcttgtatgt ggacggaggc
    25441 atacttgcct atatcggaaa acaaccttaa aagagcttta gtacactgtt tagtggagag
    25501 gttgtgaaat cagcggattg aacgaatacc gaaggacagc tgattaaaca tcatttattc
    25561 gaaaaaagag gctgggacag aagcatttaa ctccaagaaa taagaaggaa ttcacgaaaa
    25621 ttgcttttca aatttttgtg aatttcagct tatttccgaa ggagttgctt ttacttccgc
    25681 cgtttgtacg tgtttagagc gtgagacaaa agtgttcttt acttttgtcc cacgctcttt
    25741 tctgtgcgtc ttccatactt cactaagtcg atccctcttg cttcgcacca atccttcact
    25801 ggtccggaaa agatcagaga ttgttggtgt agggccgcgg tattcgttgc gccgaccata
    25861 gtataaagca gacgaagctc ttcttgccat tgcttcatca gtataatagt ttcttctacg
    25921 ccgtgattca tcagatgcgt cagtacggtt cctgaagtac ccacggcatt tgcgccgaga
    25981 caaagggctt taaatatgtc ataggcattg cggatacctc cggaggctag gatttccata
    26041 gaagtgtctg cttcatttgc ttcaagcaat gaagagactg tcgattgccc ccagtcagct
    26101 aaataactca gttcccgctt ggagcgacgg gcgttttcga tctgggtgaa gcttgttccg
    26161 cttcgaccgc tgatatcaac tgtatgaact cctaaagcag ctagatcatt gagcgtttct
    26221 cttgtcatgc caaaaccgac ttcttttacg atgaggggga cgtcaatggc tgtttgagtt
    26281 tcttgaataa gtactttcca attggtaaaa tcacggtctc cctcaggcat aaccaactct
    26341 tgaggtgcat tcaaatgaat ctgtaaggca tctgcgtgaa acaatcggat agcttctttg
    26401 gctctttcga cagaagtccc tgcaccgatg ttggcaatga ttttcccgtg aggatattct
    26461 tgtcgcataa tcgtataagt atcggctaaa gaagggactt tcaaggcagc gctgactgaa
    26521 ccagtggcaa tcatcaaatc tgcttctctt gcgacgattg caagatcttg gttgattttt
    26581 tttgtttttt cgcttccgcc agtcatcgca ttgatataaa atgggctgct tagtgtaaac
    26641 ccaactgcct gtgtacttag atcgacatca gaaactgcta tttgcggcaa agggttatgg
    26701 atgatccgta cgaagtcaaa ttcgtttttt tgtttatcat gaaaggcttt agctagtgaa
    26761 acatgttcgt cttttcgatt catcggtttt cctttctttg atcgctatag acatgtaacg
    26821 gcagtggagt gatttctgct ttttcccatg cactcattaa aggaagaatg ccagatttct
    26881 ggtcaacaat tacgattccg caatcgcccc cacctgcacc agaagatttt gcggctcctt
    26941 catactgttc agctaaatta cacaatttgt tcaaagcagg cgtttcgatg acgaccccag
    27001 tgattgcaga taaatcatgc agtaattgtc ggttttttcg aatcatctgt tggatcaacg
    27061 ttacattatt ttctttaaac cctttgatca tttcgttgac acattctgta ctatttttta
    27121 agaaaagctg ataagccacc attttatctt ctctcgaacg gtgaacttga tcgaccaaat
    27181 cagaagtaga ggcagggcta cccgtccaac caatcaataa acgtaaatct tcaggagcaa
    27241 tcaatggctc aatggataga cctggccaat ccagggcaag taactcactg atagaatgct
    27301 gagtttcttg ttcttggagc caaggatggt cgaaggttga gaaagcgatc cagccaccat
    27361 aacagctagc agcgatgtcg ccgcaggaac cattatcttg aactgctaaa ttggctagtg
    27421 ctgcaatctt gaaaatctcc aactgagata aattcaacgc gtaaaaaaca ttcaaggctt
    27481 tgaccgttgc aacggtcacg gcaccgctag aacccaatcc atatttccgg ccatttgaac
    27541 tgtctaactc acttgttact ttcagatcat aaaaggataa aagaatgttt ttttcttgtg
    27601 catacttttc agtcaagcga atagcagcaa ggatataatg aaaaggattt tcccgaatat
    27661 ctaaaactaa ttctccgttg cgtcttgtcc aacgtacagg catcccacta tattgtgcag
    27721 attggatact tccgactttt cgtgcagatt ctacagtgac tgtcacgaat tgatcgactg
    27781 cagcgataac tgctggatgg cctgtttcaa caactgcata ttctccggca atatagagtt
    27841 tgcctggtgc agatacttca atcataaaaa tctcccttta ttcaataatc gcaattcctg
    27901 gaccagcatg tgcagtaatt acttgttctt tgctaaataa tttggtaaat gtttcttgta
    27961 cctcagataa atggctgttt tccactaaaa ctttgacatt agggccagca tccatcgtaa
    28021 agtagcatgg aatgccttgc tttctcaatt gtcgcaccgc atccatcgct tttaagctgt
    28081 caggagacca gtaagtgaat ggaggctggg cagctaaagt cgttccatgc atttttagtc
    28141 cgtttctttc catcgtttct ccgagaagtt ggaaatcttt tgttttgatt gcttgtttca
    28201 attgatatag atccccttca acggaatcta accagccttg ataaaaactg gatgtttcga
    28261 ctgtccgacg catcccattt ctgctggaca cttctttttt ctggtcgttg atcaaaacga
    28321 aaaccattgc taaatcgtct tcgaaagaat cggaagggac tggcttagcg taagaactta
    28381 agtcgtcatg gcctttttcc cattcgacga aaccaccgaa aatacttcgg caagctgaac
    28441 cagacccgcg tcgagcaaat cttgaaagag agagatcatc taatccaagc ttaagagcag
    28501 tattgcaagc gcctgctaaa gcagctagcc cgctggcaga ggaggctaat ccagctgcgg
    28561 taggaacgaa attctgactg attactgaag cttttagtga gaggccggct tctttacgaa
    28621 aaaggtcaag aaactgactg actttttttg ttgctttttc gtcttgcaag gtgccatcta
    28681 gataaaattc atctaccata tagctatcag aaaagatgac ttctgtctct gtataaaatg
    28741 catccaatgt taacgaaagg ctgttgttca ttggaaggat gagttcttca tttttcttac
    28801 cccaatattt gattagagca atgttggtat atgcgcgtgc tttgccttta aacataggta
    28861 tgtactccta atccttgtat ccaagtttca gcagcacccg catcttcaag tgcttgactg
    28921 atttcttggg cttttgtttt tgtttgtgct aatgcaatca tacagccacc gcgtccaccg
    28981 ccagttaatt tggcacccaa tgccccggta tcttttgctg tttggatcaa tagattaaga
    29041 aaatcattgc tgattgtcag cttttccaga agtgattgtg attcatccat tgtctgtgcc
    29101 aacgtttctg gtgaattttc aatgattgct tgttttgctt gcttcgtcaa gtatcctaat
    29161 ttttggatca tttgtccagt ttcatgaggc tgggtttcaa agaggtgagc gacatctttg
    29221 acggcttctc ttgtttgtcc tttgattcct gtatcagcga caatcaaaaa agcatcgatg
    29281 ttcaaagaaa agtagtcgaa aggatgccct tttgtaaaat aaatcggctg caagctgcta
    29341 gtagcggctg catcgattcc actaggatta ccgtgggcga ttttttccga aagctggaca
    29401 ttttctaata gtatttcacg agacaaagga aatgctaagt aatcataaaa agcacgagtg
    29461 actgctgtgg cgactgcagc gcttgatccc attccacgtt cagcaggaat cgtgctttca
    29521 atggtcagtt gcaagttttt ttggatgtca tgctgttttt ttaagtgaat gaataatttt
    29581 ttgatatttt ttaatgcatg aggagcttcg gctaaatttc ctgaatagta ggaagaaacc
    29641 agttgatcgt ccattgcatc cagctcttca aggaatgcgg tgacttttgt tgcatagaaa
    29701 ggaaaggcaa tcgctggttc tccataaaca accgcgtgct cgcccatcaa tatgatcttt
    29761 ccgcttgatt ctccttggcc atagtttgcc ataatctaac tccttctcac gtaaaagtga
    29821 tttttaagca aaaaataaag cgcccaaaac gagttgcgct gcttcacgaa tttttttgtc
    29881 cactaagggt ctcaaaaaac attcctcctt tattttacta aaaccatctc agaagtaaaa
    29941 ctaagaatac gttttctaaa gaaaaaacac ttttttctta agaatttttt gacttttttt
    30001 cttctttgac tagaaaaaaa tacaattgac actactagat attgggggta tatttaaaaa
    30061 ggttggagtt aaacacaata tttagtgatg aagtgagctg gaggtaaatg agcgtgatcg
    30121 ttttagcagg tacaattggt gccggaaaat caagtttaac agaaatgatg gctgaacact
    30181 ttgatagtca ggcattttat gaatcgattg atgataatga agtcttgccc ttattttatg
    30241 caaaccctga acagtatgct tttttgctgc aaatttattt tttgaataaa cgttttgcaa
    30301 gcatcaaaca agcaatgaaa gatgacaata atgtattgga ccgttcgatt tatgaagatt
    30361 cactgctttt ccatctaaat gcagatctag gaagagcaac agaaacagaa gttcgtgtgt
    30421 atgatgaact gctggaaaac atgatggaag aacttcccta tgctgcccat aaaaaacatc
    30481 cggatttatt agttcatatt cgtgtatctt ttgatacgat gttggagcgt atcgaaaaac
    30541 gtggtcgttc gtatgaacaa ttgtcctttg atccaagtct atacgattat tacaaagaat
    30601 tgaacagacg ttacgatcaa tggtatgaag aatacaaaga aagtccaaaa atccaaatcg
    30661 atggagaccg ctataatttt gtggaagatc ctcaagcaaa agaagaagtc ttgaaaatga
    30721 tcgaagaaaa attagcagag attcgccaaa ccaaagtagc catttgattt acagttgctc
    30781 aaataaaggg taaaccttta tttgagcgac ttttttcttt atactggaaa caaatgtcag
    30841 gaggatagag tatgcgggaa aaacactatt ttaatcaaga ccgtaatttt tggatcaatg
    30901 tacagcaaaa cgatgtgcta gctgttaaaa acttaaaaga agaatatggc attagtgacg
    30961 agatgctgac ttattctcta gataaaaatg aacgggcgcg cgtagagtac gattcttttg
    31021 atgaagcgtt actgcttgta tcaaatgttc cgcaccagca aaaagtcgat aatcattatg
    31081 aaactagtcc tatcgctttt attttaaaag aagacggttt gtttacattt accacgccga
    31141 ataccgagta cgtgattcga ctaattcgat cgcttttgga acgaatgcca gacatgagtg
    31201 tatacagttt attgtttcgt acattgtttt tgatttctga ttcctttttt cctttaatcg
    31261 aggaagtgaa tagtgaacgt cagcggctta atctgaaatt aagagaaaaa acaacgaaca
    31321 agaatctgct gcaactttca gatttagaga tcggtttggt ttacttagtt acaggaacaa
    31381 aacaaaatgt agtactttta gaacaaatca aggcattggc tatttatcgc aagttgtcag
    31441 aaaaggaaaa agaagagttg gacgatgcgc tgatcgaagc acgacaagca gttgaaatga
    31501 cgaacttagc ttcgcagatt ttagaccagc tctctggcac ttataataat ttgctgaata
    31561 acaacttgaa tgacacgatg aaatttttga cggtctggtc gctgatcttg accgttccaa
    31621 ctattgtgac aggattcttc ggaatgaatc tccagttacc ctttacccat tccgttttcg
    31681 gatggggaat cgccttgatc atcagtttgg tcttatctat ttggatgctt attgcactgt
    31741 ggcggcggat tcgttgatct agtctttgat ctgcaaacca agggcttggg cgatcacaag
    31801 tgcttgctct tggttgacga ttagtcccgc caaagaatct tgagataaag cgattgctgt
    31861 gaagaaatta gtcgtaaagt ctaatccctt cagagaagtt cgaaaccagt tcgaaccggt
    31921 caactgattg tcagacaaaa aaaggttttt ccaagtgacc tcataaaatt cgctgtcttc
    31981 taattgacaa tgatcgaagg agacagcttt caagtttgta ctactaaagg aagccatcga
    32041 agcaatacaa tcagtgaaag tacagtctcg aagataactt tcggcaaaat tcgtacctgt
    32101 taatttacat tgatgaaaca cgacttggtg gaaactgcca ccaatccact ccagattgga
    32161 aaaatcacat ttttcaaaaa tgacattact gcattcaaaa tgacgtaaaa ctgttttttg
    32221 catcgtaagt ttttggatat gactctctct taataccata tttttggcat cgagatagct
    32281 ttggtcaccc ccgttgatca gaagaccaga gaagatctcc tcatcttcta aataaaactc
    32341 tccctttgta agaagaggaa gagaaggtgg aataggttcg atttttttca tgtgggttca
    32401 cctcgttttt ctttagtata gcaaagaagc gggaatcact gctagaaagt ctgctaatct
    32461 aatcattttc agaaaaggaa gacaaactgt atgaaaaaca ttgacaaaaa gattagtttt
    32521 tgctatacta tgatggttga gaaataaaag cagaagcacc cgcttctcgc cttagttgat
    32581 aatgtcactg ggctagatag ttttcactgg ttctattagg tgaagtacgc gcgggttctg
    32641 taagagaact cgttttttta ttgccgttta ttcggtaagc ttttctttct ctcataatat
    32701 ttggaggtga atgaccatag caaaggatat gatggttaac gacggcattc gtgcacgaga
    32761 gttacgattg atcggttcag atggtgagca attaggagtt aagacaaaag cagaagcatt
    32821 gaatattgca gaacaagcaa acttggatct tgtgttagtt gcccctggtg cgaaaccacc
    32881 agttgcgcga atcatggact acggtaaata ccgtttcgaa caacaaaaga aagaccgcga
    32941 agcgcgtaaa aaacaaaaag tgatcaatgt aaaagaagtt cgcttaagtc ctacgatcga
    33001 cttgaatgac ttcaatacaa aacttcgtaa tgcacgtaag ttcttggaaa agggcgataa
    33061 agtgaaagct tctatccgtt tcaaaggccg tgccattacc cataaagaaa ttggtcaaaa
    33121 agtcttgaat cgcttagctg aagaaactgc ggatattgca acagtggaac aaaaagcgaa
    33181 aatggacgga cgcagcatgt tcttgacgct ggcaccgaaa aacgacagta agtaatttga
    33241 atgactaact ggctgttgga cagccgatag tcggataacg aaagattttg aggaggaaat
    33301 atagtcatgc caaaacaaaa aacacaccgc ggatcagcaa aacgtttcaa acgtactggt
    33361 aaaggcggat tgaaacgctt ccgcgcgttt acaagtcacc gtttccacgg caaaacaaaa
    33421 aaacaacgcc gtcaattgcg taaagcaagc atggtttcta gtggcgactt caaacgtatt
    33481 cgccaacaac tagcaaaaat gaaataagaa gtacaaataa cagaatctga agatttattt
    33541 ttattaggag gaattataca tggcacgtgt taaaggtgga acagtaactc gtaaacgtcg
    33601 taaaagagtg ctaaaattag caaaaggtta ctacggttca aaacacactt tatttaaaac
    33661 agcaaaagaa caagtaatga attcatacaa ctacgcatat cgcgatcgtc gtcaaaagaa
    33721 acgcgacttc cgtaaattgt ggattgctcg tatcaacgca gcagctcgta tgaatggctt
    33781 gagctactca aaattaatgc acggtttgaa agttgctgaa atcgacatca accgtaaaat
    33841 gttagctgac ttggctgtta acgatgcagc agcatttact gcattggctg accaagcaaa
    33901 agaagctttg gctaaataag ctaaacaatt ataaagagga aagaagataa cgaaaagtta
    33961 tgttctttcc tcttttttta tttacaatcc tccatcaaat gaaacaggac aataacgtat
    34021 aagtctaaaa tagcataatt aaggtttttt aattgaaaac tgaacattta tggtcaccct
    34081 ttaatgaaag cgctaactac ataagttaga atgagtttga ctgatatatt agtttgctta
    34141 tcagaaaaac aaaatggacg gaggaataac atgagtgata ttattattgg tattttgtta
    34201 gttatctcat tctttttcat ggtctggtac tgtgtaaaag gctacaactt gatggtcggc
    34261 tttgccatca tggctactgt atggatggga ttagcgctag tcggaaacac gttttcacca
    34321 aacccggcga tggaagggca aggagtaatt gatgtgttga cgcatatcta tacgacgggg
    34381 ccagctgagt acgccaaatc gatcttggta aatgtcttct ttggtgcctt tttcgggcgt
    34441 gttctagtag atagcggaat cgcagctacc ctgattcgaa aggtagttga acttggaggg
    34501 gacaagccaa gaatcacgat gagcttacta tgtattgtaa ccgctgttat attcatgtcg
    34561 atgacaggaa tcggaccagt gatttctatt gcagttattg tgttgccaat cttgatgtca
    34621 ttaggtattt cagtaccggt tgcactgttc tcatttatgg gctcgattat ggctggaatc
    34681 tttgctaata tcgtcaattt caaacaatat caaacgattt atgctggttt caatccagcg
    34741 gctgaaagct atacttataa tgactatttc caaattggta tgattgggat gattgtaagc
    34801 ttagttgtgg tactaacggt cgctaatata tcaatgaaca aaaagaaacg ctatgcaatg
    34861 gcagcaaacg taccagctga aggtggcgac gcaccaatga tctcatggtt agccgtatta
    34921 ttaccagttt taggggtcgt tcttttagat cttccaatca tcttaggttt tattctagca
    34981 ggtatctggg cattgctgtt tactggaaaa ttgcgcggag gttataaaga aatctgtcgt
    35041 cagtttgcga aattatttac agatggcgca gtagatgttg caccaatggt tggtttcttg
    35101 atgaccttag cgatgttcaa taattcagct gcgtatgctt ctccttattt ttcagctatt
    35161 tttggagatt ggataccgca atcaccatta gtcttggcaa tcgtatttgc tatattgaca
    35221 ccactaggat ttttccgcgg tccaatgaat ctagtcggtt caggctcagc tattttagct
    35281 gtcgtattag ctgttaatcc aacgatgtcg ccagcctttt tgttcccgtt atttgcaatc
    35341 acaacgattg ctcctcagca tttagatatt acacaatctt gggttgcttg gggattaggt
    35401 tatacaaaag taacttctcg agaatatatg aagaaatcca tcccaactgg ttggatcatc
    35461 ggagcgatct tatgcctgat cacgttctta ttgtacggga acgcctagta aacaaaacgt
    35521 cgataaaaac gattagatga atggaggaaa agaaaatgaa acgttttgtg cgaatgggaa
    35581 ttgatgttgg cggtacacat acgaaagcag tcgcaatcga taatgcgacg cacgaaatca
    35641 tcggaaaatc ttcagtgaaa acaacccacg atgatgtccg tggagtagcc gcaggtgtcg
    35701 ttcagtcttt tcaaaattgt ttgcgggaaa ataatatcag tccagaagat gttgtgtttg
    35761 ttgcacattc taccacacaa gcgactaatg cactgattga aggagacgta gcaaaagtcg
    35821 gcgtaatcgg gatggcaaaa ggtggattag aaggtttttt agcaaaacga caaactagat
    35881 tgaacgatat cgatttaggg aataagaaaa aaatagagat tgtcaatgca ttcttacctg
    35941 tcaaacactt aaatgtagac cgtgtttcag aaacgatttc ttctttagaa agagaaagag
    36001 cggaggtctt ggtttcttct atggcatttg gagtagataa tggggaacca gaacgagttg
    36061 tttatgaagc agcatcggta aaatcgatcc ctacaacgat ggcttctgac atcacaaaat
    36121 tatatggatt gacaagaaga actcggacag cagcaatcaa tgcatctatt ttaccaaaaa
    36181 tgctagatac ggcaacctct acagaagatt ccgtacgaga agcaggggtc aatgtttctt
    36241 tgatgattat gcgcggagac ggcggagtaa tggaaatcaa tgaaatgaaa aaacgacctg
    36301 ttttaaccat gctttccggt ccagcagcat cagtcatggg ctctttgatg tacttgagag
    36361 cgtctaatgg tgtttatttt gaagtaggcg gaacaacaac caatatcggg gtcattaaaa
    36421 atggacgtcc agcaatcgat tattcaattg taggtggcca cccaacatat atctcttcat
    36481 tagatgttcg ggttctaggt gtggcaggcg gttcgatggt acgggctaat cagtcaggaa
    36541 tcatcgatgt cggtccacgt tctgcacata ttgccggtct agattatgca gtatttacgg
    36601 agacagaaaa aatcaaaggt cctaaggttg aatttttctc tcctaaagaa ggagaccctg
    36661 ctgattacgt caaggtagtg atggaagacg gagaagaagt gactattaca aatacatgtg
    36721 cagccaatgt ccttggatta gtgcaagaag aacatttttc ttatggaaat gtcccatctg
    36781 cacgaaaagc catccaagca ttagctgatt attgtcatac gacggttgaa gacatcgcag
    36841 aacagatcat ggaaaaatcc tatgctaaga ttgaaccggt gattttagaa ttggcagaca
    36901 agtatcactt ggagaaagat cagatttctc ttgtaggtgt agggggcggc gctgcctcat
    36961 tgattactta ctttagtaat aaaatgggtg tgaaatattc gattcctgaa aacgccgaag
    37021 tgatttcttc tattggtgta gcacttgcaa tggtccgaga tgttgtagaa cgtatcatcc
    37081 cttcgccaag taaagaagat atacgatcgt tgaaaaatga agcgatgaat aaagcgattg
    37141 aatcaggcgc tacaccagaa tcgatcgaag tccacgtaga aatcgatcca cagacttcaa
    37201 aagtaacggc tatcgctact ggttctacgg aagtgaaagc aaccgatcta accaaggaga
    37261 tcacaacaga agaagcacta gagcttgctg cagaggatat gcgattaaat aaaaatgaag
    37321 tttgcttatt ggaaaataca cctttctttt atgtatgcgg cgaacagaat cgttcaaaaa
    37381 atgctggaag tcttcggatc atcgatcaaa aaggatttat caaggtccaa cgtggacatg
    37441 cttcatgtat gaaaacaact gcagccaatt atatgacagc tgtcgaacaa ctttgggaag
    37501 atatggcagt ttatcaaact gaattgattg cccgaccaga attttatctc tgcttaggag
    37561 caagagtctc tgattttaca gcgacggatc tggaacaact acagcttttg atggatctgg
    37621 aagtatctac tatggaaccg gaggaagaag tgatcgtcgt tgccggaaat atcaaacaaa
    37681 cataagttag aagagttact aaacgaatta caacagatcc ccgaagaaat ttggggattc
    37741 taccagtttc ggcgagattt attttggaaa aagattcctt tgtccaagca gaaaattctt
    37801 atacaacaat caatcgattg tggtatcgaa acggcatgta gcatcaaaaa aaagtaccct
    37861 tttgccgatg taggagaaat ttgtgaacaa atggctgttc caatcgtttc ctgtgaatca
    37921 gagcaaataa acgaacgaat cacttttgca acttatgcag aagatgaagg gattcgattg
    37981 atgacggagc cgttagaaaa attaaaatgt tcaggactag cttcgatctc taaagaaaca
    38041 gcgcaagctt tgattattgg acatgaacta tttcaccaca tcgaagcttc tgttaaggga
    38101 atttatacgc aaagcgaaaa aattgtgctg tggcggttgc ctttttatac acatcaatca
    38161 aacattcgtg cattgagcga gatagcagcg atgagttttt caaaagagat gaatcaaagc
    38221 gatttttcgc cttatgtatt agaggcagtc ttactttggc catataatga aattcgtagc
    38281 caagggatct tagaagaaat aaaaaaaata gaaaaaagat gtacggagta tgatttagat
    38341 tacaaataaa gagactgtga caaaagtcgt gtcacagtcc tttttttccg aataaacgat
    38401 gttctcctgt caactcctcg gtcacaagtc aaaatattca acaaacatga gaagctgttt
    38461 tttgaaattg ttccttgtga ctcggagatg aacggcaggc tcacgacctc ttggaaaacg
    38521 gtgttcaaaa gcttgcatct gcggtaataa gtccagccaa gttaaaaaca taagaagcta
    38581 tttttacttg gctgttctta ttacttgatg cagggcagct ttttcacaac ctctcaataa
    38641 acggtgtgca atcagctgac cctcggtatt agctcaaaaa aaacggcaaa atatgaggaa
    38701 ctattttgcc gtttctttct ctaatactca ggtcaaaacg ctgattccaa aacctcttat
    38761 ttgatgggtc tgtcctgaat atcttcaaaa taatcggggt aattatgaat cacgtattct
    38821 tgctcctcga taatcatatg taaatgcatc gtgcaaagaa atccgacttc atcaaagtta
    38881 tgatcaatca ttgattgaag cattgtctga tgttcatcta atactcgacc ccagtctaat
    38941 tctgaaatcg tcaaacgtaa ccatctgaaa cggttcaagt gcgtactata actttctagc
    39001 caatcccaaa tttctcgttt tccagcaatt tcataacaag ttcggtgaaa atcagtatcc
    39061 aaatcaaaaa aagctttttt attttgagcg attactgcct gatcggtttt tccaactttt
    39121 cccgcgtata acgggctaat gaagcagatc ggatatcgat ttttgaaaca taagtgccgg
    39181 actgtggaat ggtttttaca agctcttgat tgcgcagttg gatcagtgct tctcgaatcg
    39241 gtgtacgccc gatagctagt tgttcttcta acactttatc ggagatttta cttccaggtg
    39301 ctaactcgga ataaatgatt tgtttacgta tagattcata agcttgctgt tgcaaattat
    39361 tgataaccat ttaaccttcc tttctatgca gatataatct attataacat aaatcgctta
    39421 caaatcgtgt gggcataaaa acacagtctg caaaaaaagc cctgataggc atgcctatta
    39481 gagcctcgaa aagaaaaata ttgaatcaat ctggtcgtac ctcttgtatc ggtttgacac
    39541 gaccgccgat tcttttagca aaagcttcgg attctttttt gtctttgaaa atgagcagat
    39601 tgtctaagtt tttttcccga gtgcgacagc cagttttatc gatgtaaccg tgcattactt
    39661 taacgacata catggggatc acctgctttt ttcttttcat tatacgaact actcgacaca
    39721 atacaagaaa aatgcttaga cggtctttat taagaattta catcatccaa agaagcgtac
    39781 gcttggaata actgatctaa ctccggattg actttgctca gcttcactaa tcgttgcgaa
    39841 tcagaaagta aaaaacagtg tttactactg ccagtagttt ttaatttttt gtcttcagtt
    39901 cccacaattt cgtagctaaa atccaaccgt gtccccgtat acttttggat agttggatgg
    39961 atgctcactt tttctccgta atggatcatt tctttatagc tgcaatttac ttccagaacg
    40021 gggatgatga tcccagattc ttcgattttt ttatagggaa accctagatg taccaataag
    40081 gctacccgag cctcttcaaa ccagcggata taattgctgt gatgaataat ccccatttga
    40141 tctgtttcat aataaaaagg ttctcgcaca taacctgtaa atttctccat gactcatgcc
    40201 tcgttttcca ttgatttttt acaaaaataa ttcatccatt tcggaagtgc ttcgctgatt
    40261 tgtgtcggca aaacaatata ttgttctttt gccagctggt ctccaatgaa actatgaaga
    40321 taaatagctg ctgcaatcgt ttggtcattt tgaggaaact gggctaaaaa tcctgtgatc
    40381 atcccagcta aagtgtcacc catgccgccc gttgccatag cagcagaacc taaaggattg
    40441 gtgtagaagt gctggtgacc ataaattttt gtctcatgac ttttcaaaac gagcacagca
    40501 ccgatttcct gttgcttctt tttgttttct ttatcccgtt gttcttgtat cggtagagaa
    40561 ctcaaccgtt gccactccat ttgatgaggt gtaagtacag tttgttcggg atagggtagc
    40621 aaaagatgat tagcagcaag taaacttaaa gcagagccat caatcaccag ccattgttct
    40681 tttgattggt tttctagtac ttgtttgaaa cgttccaaac tcttagaaga agtacccaat
    40741 ccgggaccaa tcaagagtac atctgcttgc tttattacgg aaagaaactg gtcagtatcc
    40801 gtccaaacta caatcattgc ttctggcaga tgactgtgaa gagcactccg atttttttca
    40861 tcagttacta cagtcgtgag acccgctccg ctgtgtacgg cagctaaagc actcataatg
    40921 attgctccgc catattgttc attgccgcca atcaaaacga tacgtccaaa tgttccttta
    40981 tgtgaaattt ttggacgagg tgtgatgact cttttcacta gttgttcgtt tatcagcatc
    41041 taaaaacctc cttttactca ttatagcgta tatttttttt agagaaaaac agataagaaa
    41101 aggaattgtc agattttttg aactattttt ttctgtaatt tgtggtatca tgaacacgaa
    41161 gacttaaata agtggaggat taactttatg acaattgatt ggcaaaaaga agtagaagca
    41221 cgtaaagaag acttgcttga agacttgaaa aatcttttac gtgtcaacag cgagcgcgat
    41281 gactcaaaag taacaccaga tgcaccattt ggacctggac ctcgcgacgc attgaaacat
    41341 atgttagctt atggcgaacg tgatggattt aaagtaaaaa atgtcgataa ctatgcaggg
    41401 catattgatc ttggcgaagg agacgaaacg ctagggatat ttggacacat ggatgtcgtt
    41461 cctgcaggag atggctggga cacagatcct tatgaaccag taatcaagga tggaaagatc
    41521 tttgcacgcg gatcaagcga tgacaaaggt ccaagtatgg cagcttacta tgcgatgaag
    41581 atcattaaag aacttgactt gaaactatca aaaaaagttc gcttcgtagt cggcagcgat
    41641 gaagaaagcg gctggggcga tatggcttat tatttcgaac atgaagaaga accagatttt
    41701 ggtttctcac cagatgctga attcccaatc atcaatggtg aaaaaggaaa tgtttcttta
    41761 gctttacgct tcaaaggcga caatgcagga gattatgtct tgaaatcttt tgtttccgga
    41821 cttcgcgaaa atatggtgcc aggaacagca actgcagcac ttcaagtacc aagtgcagat
    41881 gcagctatcg cgatggaaga agcattttac caattcatcg aagcaaatcc agtaagcgga
    41941 acgattgaag cggacaatac gtatgtaaaa atcgaattag ttggtaaagg cgcacatggt
    42001 gcaagcccac aatctggtat caatgcaggt tctttcttgg cattgttctt agataactat
    42061 gaattcctag gatctgctaa acaatttatc catgtagcag ctgcttatgt ccatgaagat
    42121 ttttatggag aaaaactagg agtcgcttat gaagatgaaa aaatgggcaa attgacaatg
    42181 aatgctggac tatttgcttt tgaagaaaat ggtacagagg aagcgaactt catcaatatg
    42241 aatttccgtt ttccaaaagg tgtaacagta gacggattgc aaagtgacat cgaacaaaca
    42301 gtggggcaag aaggcgcaac agttactcga ggtgctcgcg taatggaacc acattacgta
    42361 ccaatggatg atccattggt ggctacatta ttgcaagtct atgaagacca cactggagaa
    42421 aaaggctacg aacaaatcat cggtggcgga acttacggac gtttgttgaa acgtggcgtt
    42481 gcttatggag cgatgttccc aggatatact gatacaatgc atcaagcaaa cgaatttatg
    42541 agtcttgatg acttgttcag agcaacagca atctatgcag atgccatcta tcgtttggcg
    42601 aaataattaa ttaaaaagag gatcaagaat tgcaaattat ttttgcagtc ttgatccttt
    42661 ttttactttc tactgtggta ttcatgataa acatgatata gattcaattc atattctttc
    42721 ttagcgttcg tgacgactgt atccaaaatc aaccctgtta ctaatgaaag aagtgctaaa
    42781 gtcatcaatc cagtacttaa aatcgcagaa gggatgcgtg taataaagct tgtcagcata
    42841 tattcgcgaa tcacaggaat ccccgtgacc aatccaaata aaaagaagaa gatggtccaa
    42901 atcccaaaga aaagcaaagg cttataatct ttaaacattt taataatcat catgatcact
    42961 ttgaatccgt cagagaatgt attcaatttt gattcgctgc cttcaggacg atcacgataa
    43021 tcgattggga tttcaacgaa cttgaatttt ttatctaaag catggatcgt caattccgtt
    43081 tcgatttgaa aaccagaact cataatagga aaacttttga caaagatacg attgaatcct
    43141 cgatagccgg tcatgacatc aagaattttt gttttataca ttctagtaat tgtatttcta
    43201 acaaggttat ttccaaaatc gtggaaaggt ctcttattct catcaaagta ggttccattt
    43261 gataggcgat caccaatgac catatctgct tcaccagaac gtaatttctc gagcaaacca
    43321 tgtacagctt ctgcaggata agtatcatcg ccatctacca ttaaataata gtcggcatcg
    43381 atatcaaaga acatttggcg gatcacattt ccttttcctt gacgaggttc tttttttacg
    43441 attgctccac cttgaacggc caattcgtat gttcgatcgg tcgaattatt atcatagaca
    43501 taaatatctg cttctggtaa ttctcgttta aagtctgcaa tgactgttga aattgttgct
    43561 tcctcattgt aacaaggaat cagaacagca attttttctt gttgttccat ttttcactct
    43621 ccttaactat agaaaacaaa agctaaatta aaaatacctc ataatcaaag gaaatgctag
    43681 tttttcccgc taaatatcat ttatttaaaa agaaaatact ggaatatatg tttggaaagc
    43741 tctatctaaa aaaccaccca ctacaaaaga aggacatgat acctctcttt tgaatagtgg
    43801 gtgcgtattc gttctctcac ttttttgacg tattaatctg ttgcaccttt ttttcttgaa
    43861 atttctaata cggttcctgt atgagcatct gctaaaaatt cataataaac agtttcgcca
    43921 tcttctattc gagaaagacc tccccgataa gcactcgacc gaacggcgaa tttcctaata
    43981 ggttcctttt caaaagagat ccaagaacct tcgattgcac cttcttttag aaaagatgac
    44041 ttgatatttt caagtacttg gtctgctgac aatacttttt tgcgatgata ccaaatcgtt
    44101 gaagctaccc cgctcaataa tcctagaccg attccaactg ctaacccgcc tttaaaatag
    44161 cttagttcgc tttcttcata catgtggaca tacctccttc ttctcacttg ttactccttg
    44221 tgcttatttt accacactct catattttct ttgaaataaa taaccgctac cagaaaaaat
    44281 aagctataat aaatacgatc ggtctgcaga aaaaatcata ttttatccgc agatcaatat
    44341 aagtctgaga ggagtttagt ctgaaattta gacgaatagc atatggaaga aaaaacattt
    44401 caacgaatca aagagttaac agaattacaa ggaacaagcg gttttgaaca agatgttcgc
    44461 gcttatatgg aaagtcatat ggaaccgctg gtagatgagt tacagttaga tggtttgggc
    44521 ggcatttttg gtctgcgcca tcatgaagaa gcggatgcac cccgtgtaat ggtcgcagca
    44581 catatggatg aagtcggatt catgctgaca caaatccaag aaaacgggct ttttaaagtc
    44641 gtacctctag gcggctggaa tccttacgtt gtttctgctc agcgttttac acttaaaacc
    44701 tctactggta agaattatcc atgtatttct tcttccgttc ccccacattt attgcgagga
    44761 acaagcggac aaaaatcagt agaagtaacc gatattttgt tcgatgctgg gtttgaatca
    44821 agagaagagg caatgagtta cggtgtcctt ccaggagaca caatcgttcc ttacgctgaa
    44881 acgatcaaaa cagccaacgg aaagaatatt atcagtaaat catgggacaa ccgctatggc
    44941 tgtacaatgg tattagaagc tttagaagcg ttgcaaaatg aaacattagg tcatacattg
    45001 attgcaggcg cgaatgtcca ggaagaagta ggcttgcgtg gttctaaagc ttctgtcaat
    45061 aaattcaagc cagatctgtt ctttgcagta gactgctctg cagcagatga tacagtgacg
    45121 aaaaatggca cattcggaca tttaggagaa ggtacattga tgcgtatcca agatccaggt
    45181 ttgatcatgc ttcctcgttt gcgcgagtac ttgctggata tcgctgaaac aaacaatatc
    45241 ccttatcaat actttgtttc aaaaggcggt acagatgcag gtgctgctca tacacaaaac
    45301 gaaggaatcc caagtacagt gattggcgta gtgggacgtt atatccatac gcatcaaacg
    45361 atgttcagta ttcgcgattt tgaagctgca cgagaaatgt tgattcaaac actgaaaggt
    45421 ttggataaat caacagtgaa tacgatcgta tacggaaaat aatgcgatag tgaaactata
    45481 aaatctggca aaagattgct ttttgccaga ttttttttat aaaaagagga tcaatgtttg
    45541 ttagttcgaa agaaaggtgt ataatttaat tgaaaaatac ataaacagaa agtagaggac
    45601 aaagaatgat tatcccaaat agtttagaag aattagcagg ctacgtagaa actggaaaga
    45661 gtgtattttt ctttactgcc ggctggtgcg gagactgccg ttttatcaaa ccgcaaatgc
    45721 ctgaaattga aaatgacttt tctgattggc aatttattga agtagaccgt gacaagtaca
    45781 tagatgtagc cgctgaatgg aacatttttg gtatcccaag ttttgtcgtg atccaagacg
    45841 gaaaagaatt aggtcgtcta gtgaataaag atcgtaaaac aaaacaggaa atcgaatcgt
    45901 tcctagaaag tgtaacaaaa ggctgacatc tgttaggagg ggtcaagatg aatcaagaat
    45961 ataagaatat tttagtaggt atcgacggta gtgaacaagc acttgctgct ttcaaaaaag
    46021 cggtagaagt ggctcgccgt aataatggga aagtatatgt agcaaacgta atcgatcagc
    46081 aattttataa ctttatgggc tatgcaccta ttgatcaaaa tctagtcgat cagcaaactg
    46141 aaacagccaa ggaaatgatc gaagaatgta aagaatatgg gaaatctgtt gattacacaa
    46201 atatagaagg aattattgca tatggttctg ttcgtgaatc catggcagtc aaattgccaa
    46261 aaaaatatga gatcgatcta atcatggttg ggcagtcagg tctaaatgca gtcgaacgct
    46321 ttatgacagg aagtgtagcc agctacgtga tacgtcattc accttgtgat gtcttgatcg
    46381 tttctgacga agaagaacag ccaagtaatt aagcaagtgg aacttgtacg acctttttaa
    46441 tcaattaact aaaacagtaa agggactgtg acaaaagtct tgtcacagtc ccttgttacg
    46501 aataaatggt gttccagaag aggcttcttc ggaaataaag catgaaaaaa atttcatgca
    46561 gtgaatgcaa ttttttgtta agataaatct cagcaaagga taatggagga aagaacatga
    46621 tttttgctta taacaaagca cacgtcggag acaccttgat ggttattata gccgacgata
    46681 aaggaacaga aaacactgtt gaacgcaaat ggaatgttgc tcggatcaaa gatgaacaag
    46741 gtcaagttgt tgcttggaac tttttccata tctccgatca tctaacaatc gaagggaacg
    46801 gccaagtaag cttaacagat gaggaattag cgaaattgaa tcgattgatc aaagaagcag
    46861 gattcgaaga acagcttgaa gctgatcatg aaccgaagat cgttgtcggg tacgtaaaaa
    46921 catgcgtccc acatcctgat tctgaccatt tatcgattac tgagacagaa gtagacaatg
    46981 gtacagtatt gcaaatcgtt tgcggtgcac ccaatatcga agctggacaa aaagttgtcg
    47041 ttgcaaaacc aggagctatg atgccagatg gaatgatgat ctggccagga actttgcgag
    47101 gggtagatag ctatggaatg atctgttccg ctcgtgaatt gcatttgcca aatgctccag
    47161 caaaaaaagg aatcttagta ttgcctgagg atgccgtagt cggagaagca tttccaaaat
    47221 aaagaggttg tgacaagtct ttgtcacaac ctctttttta ttaattttca ctattttgat
    47281 tttgttttaa tgccgattga tcgatcgtca attcaacagt agttgttttt tctttcgagc
    47341 cttcatagta agtgattttg acagaatctc ccactttttt cttatacaaa gcagattgaa
    47401 gttctacacc agaagaaact tctttgtcat cgatcttagt aatgacgtcg tattgtttca
    47461 atccagcttt ttcagccggt gtagctgttt ggacatttgt cacgatgaca ccgttagtta
    47521 cagatgaagg aatcttcaag atttgttctt gttgctgagt agaaacggca gataagtcga
    47581 ccattgtgat acctagagct ggacgtgtca cttttccgtc tttttccagt tgattgatga
    47641 tattcactac atcgttactt ggaatagcaa atcccattcc ttctacgctt acattagaag
    47701 tagattcaga agtacttgcg atcttacttg agttgatacc gataacttgt ccttcgatat
    47761 taactaaagg accaccagaa tttccagggt tgattgctgc atctgtttgg atcgcattga
    47821 tattgactgt ttcgttcgat tcattcgtac ttgtcacttg tcggttcaag gaagaaatga
    47881 ttcctgaagt gacagaattt gcatattcag atcctagtgg ggaaccaatc gcaatcgcag
    47941 gctcaccaac cttcagagca cttgagtcac caaaagaggc aactgtttcg actttgtctg
    48001 aattgatctt caacaccgct aaatctgaat aagcatctgt tccaactaat tcagctttta
    48061 ccttcgtacc gtctttcatc aagacttcaa gaccttgctg gccatctact acgtgattat
    48121 tcgtgactac ataagcagta ttcccgtctt ttttgtagat cacgccgctt ccttcactat
    48181 aagcttccaa attactatca tctgagctgc tactttcttc ttgctgcccg aatagtccgc
    48241 caaaaccgct tgattggttt tgactttgta agttgataac agaaacgaca gcgtcttgaa
    48301 ctttatctac cgctttggtg atatcagaat ctacattgac tttgacattt tccacaactg
    48361 tttcaccggc agaattctga ttgccgcttg tagcagtaga actattgttg ccagtgccca
    48421 tcgctgcata aaaaatgcca gctgtcagta gtcctccaac gatccctcca acaagcccca
    48481 gacctaactt acgccagagg ctattatttt tacttttttt catctttggt gtcacatttt
    48541 ttctatccat gtgttcctcc tccaattaca ttcatttatc tactgttagt atagtcttat
    48601 ttgttgactt tagtctactt tgagactgtg aactttttat gaaaaacttt aggaaaaatc
    48661 attgttttca gatgaaaata tttgattttc tttttccaca gatactgtgt aaaactacgc
    48721 ggataggatt ggaaaaataa gggataaaac atatccacag cctgtgtata aagtggataa
    48781 attcttataa aacgtatgtt tgcctaatga atgtgatgaa ataaggtaaa ataacactgt
    48841 tttctgtgga taaacctgtg gatgttgtgc ataactgttg gggaaatctt tttaacaaaa
    48901 atagccaaaa taaacatata gacgaaaaaa ttgattataa taaacaaagt gagcatgaag
    48961 accaaaggag agaaaacatg aatatcaaaa ttatctcagt aggaaaatta aaagaaaaat
    49021 acctgatcca aggtatcaat gagtatgtca aacggctgaa tgcctatgca aaaatcgaat
    49081 tgatcgaagt tcctgacgaa aaagccccgg agaatttaag cgaagcgcaa atgagacaag
    49141 taaaagaaaa agaaggggaa cggatcttag cgaaaatcaa agaacaagaa tacgtctatg
    49201 ccttagcaat tgaagggaaa aatcctacaa gtgaatcttt tgctaaacaa atcgaccaat
    49261 taggtatcca aggaaaaagc caccttgttt ttgttatcgg cggctcttta ggactcagcg
    49321 aagccgtcat gaaaagaagc aatgctcaga tctcttttgg aaaaatgacg tatccacatc
    49381 aattgatgcg tctgatcctt gtcgagcaaa tctaccgtgc cttccggatc aatgcggggg
    49441 cgccttatca taagtgatgc ggtttttatc attgatccta aaaatcttag caagacaaaa
    49501 agtacgtaag aaagtaaaga ctaaatactt cggaggaaca aatgaataac aatgataggt
    49561 tattgcgatt gcgttatgcg attgatttga aagatacgga tttgattaaa gcttttgagc
    49621 taggcggtgt accactgact aaagaagaag ctcaggcggt actgaccaaa gtacaggata
    49681 agaacaaaga taatgcagaa aataatgtgt atgaaaaaac catcaacaac caagtttttg
    49741 acgcattcct aaatggcctg attctcttgg cgcgtggtcc gcaaaaagat aagccgatag
    49801 tagacacgcc gcaaaaaagc aaggaaatca aatatatcaa caatgtgttg ctaaaaaaat
    49861 taaaaatcgc cttgtctatg accactgatg atattttaga cgtttttgct gaggcagaaa
    49921 tctatccatc aaaaggcgaa atcggggcat ttttgagaaa agaaggccaa cgaaatttta
    49981 agccttgcgg agataaatat atgcgtaatt ttctcaaggg gttaggaatt tataatcgga
    50041 gaaaagtata aagaaatttc atgagaaatc aaaacaatgg ttgttttgat gagagctagt
    50101 ttttgtatga gattaaaata ttatcttaat cgaggagctg gattggtttt atgaatgatg
    50161 aatataagaa tgatgaagat aagatgcttt ttgaagagat agagaatcga tgtaggctca
    50221 attttgagct tcggggaaag atgtctttaa tacaacaaaa aaagtattta gcgaataaat
    50281 cagagtttac tctgggacat gttgaaaaat taatctcgga ttggattagt agtagaagcg
    50341 aatttacaaa aataaaacag ccgattaaat ttgacatgaa aaaacttttg ttaaataaga
    50401 gtgagatagg taatagagat caatatatta gagctaaagg gcaagaaata attgattcat
    50461 taggtgaaat gaggtcatac aattatttgt atgtaacaca tagagctgat ggaatggtca
    50521 ttactgtggg gaaatcttct tctaatgata tttttttaga tggagatctt ttttatcaac
    50581 tcaatacaaa tcacttgtct ggcactgaaa atataatttt aaggacggaa tatggcaatg
    50641 aaatatttgc aaaatatgat gagattttaa aaaattattt ggactgggct tggataattc
    50701 cggttgagtc aggagatgct aagaaactgg agagattatt gggcgatgaa ctaattaata
    50761 aaaaagtacc aattttaaat tattattccc atagacaata aaaggctatt tttcatgata
    50821 atactagtta taactgtaaa aatggaagaa aatctgggaa agaagttttt aaataagtgt
    50881 attgttcgat tttaataaat aataagcaat accatccgtc tgtgttgcgc aacatcgtac
    50941 tacaatgaat attttttcac aaaaagaaaa tcatccatcg aatgaatgga aggttttagt
    51001 atacacgagg ttaatgcccc ctcttttata atcagaggag tgaggttttt tctatgaatg
    51061 tttctatttt cttattgcta gtctagtttc tcttacgatg aaattgggat tctattccag
    51121 tttttattga tttgctgata aaataacttg aatggtggat ataaacatga taaataagag
    51181 aagaataaca aaacaaggtt gtgaaatgat tctcaaatga atataataga aagaaaaagg
    51241 aggaagaatc aatgaaaata gcaattgcag gcgctggcgc aatgggaagt cgctttgggt
    51301 taatgcttca ccaaagtggg aacgaagtat tattaatcga tggctgggca gaacatgtcc
    51361 aacaaatcaa agagcatgga ttacaagcaa attttaatgg taaagaggta gaagcaaaac
    51421 taccaatcgt tcttcaatcc gaagtagaaa aagaagatca agttgatctg attattctat
    51481 ttaccaaagc gatgcagctg gaaaaaatgc tgcaggatat ccaatcatta atcaaaaaag
    51541 atacagaggt cttatgtcta ttaaatggta tcgggcatga agatattatt gagaaatttg
    51601 taccaatgga aaatatctat attggaaata ccatgtggac ggcaggtctt gaaggtcctg
    51661 gtcaggtcaa attatttgga agtggttcag tagaattaca aaatttaggt gatggaaaag
    51721 aagcagctgc aaaaaaatta gcagacaaat tgtctgaatc aggattaaat gctcattttt
    51781 ctgacaatat tcactattct atttatcgca aagcatgtgt gaacggaaca atgaacggac
    51841 tatgcacaat cttagacgtt aatatggctg agctaggaaa aacatcgact gctcataaaa
    51901 tggtggcgac gattgtcaat gagtttgcca aagtagcagc agtagagaag attgaactag
    51961 atgtcccaga agtcattgca cattgtgaat cttgttttga cccggaaaca attgggttac
    52021 attatccttc aatgtatcaa gacttgatta agaaccatcg attaacagaa atcgattata
    52081 tcaatggcgc aatttctaga aaagggaaga aatatggtgt tgcgacgcct tattgtgatt
    52141 tcttgactga gcttgtccat gcaaaagaag atagtttgaa cgtaaaataa aggagagatt
    52201 gaatggaaac ttcacaaaaa atatcaccga aaatttttct gaataaagtc ctcgctggta
    52261 cagcaacagg aatcattatt ggattgattc ctaatgcagt attaggtg
//
LOCUS       DACGEU010000009        49123 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.009, whole genome shotgun sequence.
ACCESSION   DACGEU010000009 DACGEU010000000
VERSION     DACGEU010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 49123)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49123)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49123
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.009"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            61..873
                     /locus_tag="IXR40_000509"
     CDS             61..873
                     /locus_tag="IXR40_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HAQ4360383.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            870..1670
                     /locus_tag="IXR40_000510"
     CDS             870..1670
                     /locus_tag="IXR40_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HAQ4360384.1"
                     /translation="MKQRVVTAAVALVLFIPIIWIGGIAVELTAAILAVIGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            1831..3099
                     /gene="rseP"
                     /locus_tag="IXR40_000511"
     CDS             1831..3099
                     /gene="rseP"
                     /locus_tag="IXR40_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HAQ4360385.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAILLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPDKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            3167..4876
                     /locus_tag="IXR40_000512"
     CDS             3167..4876
                     /locus_tag="IXR40_000512"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HAQ4360386.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPERDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTNLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELVNTLPILLN
                     QGE"
     gene            5088..9446
                     /locus_tag="IXR40_000513"
     CDS             5088..9446
                     /locus_tag="IXR40_000513"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HAQ4360387.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIH
                     IQLGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSF
                     IVKKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYA
                     PEGEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGK
                     KAGVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAV
                     KMYKGNVIESFDEFIDPGHPLSRTTVDLTGITDGMVRGSKSEEEVLRMFLEFSKDTIL
                     VAHNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSL
                     EQHHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILA
                     KNQAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKG
                     VEEARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVAT
                     GNVHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEI
                     VVENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRL
                     KKELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAP
                     HYYCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPD
                     IDLNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSA
                     EVDRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHS
                     IHDNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIY
                     SKTGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDAT
                     LAEVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVP
                     DWYIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMC
                     KGKDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFV
                     IEGDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGV
                     LKDLPDENQLSLFDML"
     gene            9591..10064
                     /gene="rimP"
                     /locus_tag="IXR40_000514"
     CDS             9591..10064
                     /gene="rimP"
                     /locus_tag="IXR40_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HAQ4360388.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            10087..11262
                     /gene="nusA"
                     /locus_tag="IXR40_000515"
     CDS             10087..11262
                     /gene="nusA"
                     /locus_tag="IXR40_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HAQ4360389.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            11284..11577
                     /locus_tag="IXR40_000516"
     CDS             11284..11577
                     /locus_tag="IXR40_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HAQ4360390.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            11574..11885
                     /locus_tag="IXR40_000517"
     CDS             11574..11885
                     /locus_tag="IXR40_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HAQ4360391.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            11898..14204
                     /gene="infB"
                     /locus_tag="IXR40_000518"
     CDS             11898..14204
                     /gene="infB"
                     /locus_tag="IXR40_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HAQ4360392.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSNDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            14231..14578
                     /gene="rbfA"
                     /locus_tag="IXR40_000519"
     CDS             14231..14578
                     /gene="rbfA"
                     /locus_tag="IXR40_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HAQ4360393.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKTAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
     gene            complement(14735..14908)
                     /locus_tag="IXR40_000520"
     CDS             complement(14735..14908)
                     /locus_tag="IXR40_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAQ4360394.1"
                     /translation="MIFLLTVNGPTNSNFYGAGSTDLLVTWLYLTVTKIDYNLASVIG
                     ILIFIYMQKFIYY"
     gene            15356..17718
                     /locus_tag="IXR40_000521"
                     /pseudo
     CDS             15356..17718
                     /locus_tag="IXR40_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase family protein"
     gene            18086..19009
                     /gene="truB"
                     /locus_tag="IXR40_000522"
     CDS             18086..19009
                     /gene="truB"
                     /locus_tag="IXR40_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HAQ4360395.1"
                     /translation="MDGLLPLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEKKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVERFKRVDITDEVWQKVKNGMRLDYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            19013..19954
                     /gene="ribF"
                     /locus_tag="IXR40_000523"
     CDS             19013..19954
                     /gene="ribF"
                     /locus_tag="IXR40_000523"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HAQ4360396.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGETWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            20306..21091
                     /locus_tag="IXR40_000524"
     CDS             20306..21091
                     /locus_tag="IXR40_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAQ4360397.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWVNNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENNKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            21104..21955
                     /locus_tag="IXR40_000525"
     CDS             21104..21955
                     /locus_tag="IXR40_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transporter"
                     /protein_id="HAQ4360398.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(22079..22531)
                     /locus_tag="IXR40_000526"
     CDS             complement(22079..22531)
                     /locus_tag="IXR40_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4360399.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQFREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNYVVNFSQWINEKLLIQTDISLVS"
     gene            complement(22996..23364)
                     /locus_tag="IXR40_000527"
     CDS             complement(22996..23364)
                     /locus_tag="IXR40_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chaperone"
                     /protein_id="HAQ4360400.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            23514..23996
                     /locus_tag="IXR40_000528"
     CDS             23514..23996
                     /locus_tag="IXR40_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA editing protein"
                     /protein_id="HAQ4360401.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            24033..25043
                     /locus_tag="IXR40_000529"
     CDS             24033..25043
                     /locus_tag="IXR40_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HAQ4360402.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPTWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQSSEKYQKVWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTIRHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(25158..25871)
                     /locus_tag="IXR40_000530"
     CDS             complement(25158..25871)
                     /locus_tag="IXR40_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360403.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIRQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLIDVTVIDN"
     gene            complement(26061..26651)
                     /locus_tag="IXR40_000531"
     CDS             complement(26061..26651)
                     /locus_tag="IXR40_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HAQ4360404.1"
                     /translation="MKTAITFLLEEYADWEGAYITSTLNQNEKWQNKTASIQSEVTSI
                     GGLKTKIDYLIEQIPEKVDLFIMIGGNSWDIKNHHLYQIIDKLLKTDVPVAAICGAVD
                     YLAQSGLLQGYKHTGNAQFPWLESENYQNKEDFIEQQAVKDRNLITANGTAPIEFTDL
                     ILQAVHFETEEIREKTIRLYKLGFYDYYKKYGDPFS"
     gene            27135..27362
                     /locus_tag="IXR40_000532"
     CDS             27135..27362
                     /locus_tag="IXR40_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HAQ4360405.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            27378..28544
                     /locus_tag="IXR40_000533"
     CDS             27378..28544
                     /locus_tag="IXR40_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HAQ4360406.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMKIMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYLDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNAHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            28778..29821
                     /gene="hrcA"
                     /locus_tag="IXR40_000534"
     CDS             28778..29821
                     /gene="hrcA"
                     /locus_tag="IXR40_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HAQ4360407.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEDKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            29915..30478
                     /gene="grpE"
                     /locus_tag="IXR40_000535"
     CDS             29915..30478
                     /gene="grpE"
                     /locus_tag="IXR40_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HAQ4360408.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            30529..32358
                     /gene="dnaK"
                     /locus_tag="IXR40_000536"
     CDS             30529..32358
                     /gene="dnaK"
                     /locus_tag="IXR40_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HAQ4360409.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            32509..33675
                     /gene="dnaJ"
                     /locus_tag="IXR40_000537"
     CDS             32509..33675
                     /gene="dnaJ"
                     /locus_tag="IXR40_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010767443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HAQ4360410.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(33757..34422)
                     /locus_tag="IXR40_000538"
     CDS             complement(33757..34422)
                     /locus_tag="IXR40_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar diacid utilization regulator"
                     /protein_id="HAQ4360411.1"
                     /translation="MELDFSSPYYVVVGQLSDNQQLCQERINPLLELLERVFSYYGQA
                     LLTVHRQQIIILVNRISRASLLSLLDKIQTKFNKMYQLQLNFGIGSLCYTEQETPQSF
                     LHAKQVCEWIAFHQSVNEIRFFEDLDLGIVLPAIPSDQRTLYVKRILKSLTEEEVHLF
                     KKTLACFSKNNGSIKNCSEELFIHKNTLQYRLNKFHSLTGYTPRNYDDYHILKLAFLL
                     VQT"
     gene            34398..34571
                     /locus_tag="IXR40_000539"
     CDS             34398..34571
                     /locus_tag="IXR40_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HAQ4360412.1"
                     /translation="MEKKNQAQLSEGGIDYVLDIINEPMVLSYAMEQVERLLVCAGKQ
                     AMRLIRLGEKIRR"
     gene            complement(34616..35353)
                     /locus_tag="IXR40_000540"
     CDS             complement(34616..35353)
                     /locus_tag="IXR40_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAQ4360413.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(35355..36857)
                     /locus_tag="IXR40_000541"
     CDS             complement(35355..36857)
                     /locus_tag="IXR40_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAQ4360414.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            37116..39110
                     /gene="uvrB"
                     /locus_tag="IXR40_000542"
     CDS             37116..39110
                     /gene="uvrB"
                     /locus_tag="IXR40_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HAQ4360415.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQIRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKDAAKALDFETAANVRDMILELKASK"
     gene            39120..41936
                     /gene="uvrA"
                     /locus_tag="IXR40_000543"
     CDS             39120..41936
                     /gene="uvrA"
                     /locus_tag="IXR40_000543"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HAQ4360416.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQEIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            42199..43464
                     /locus_tag="IXR40_000544"
     CDS             42199..43464
                     /locus_tag="IXR40_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HAQ4360417.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            43468..44199
                     /locus_tag="IXR40_000545"
     CDS             43468..44199
                     /locus_tag="IXR40_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HAQ4360418.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLRPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTALQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSEALDTASEK"
     gene            44334..45218
                     /gene="rapZ"
                     /locus_tag="IXR40_000546"
     CDS             44334..45218
                     /gene="rapZ"
                     /locus_tag="IXR40_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HAQ4360419.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            45215..46213
                     /locus_tag="IXR40_000547"
     CDS             45215..46213
                     /locus_tag="IXR40_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HAQ4360420.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAINR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            46247..47182
                     /gene="whiA"
                     /locus_tag="IXR40_000548"
     CDS             46247..47182
                     /gene="whiA"
                     /locus_tag="IXR40_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HAQ4360421.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            47725..48375
                     /locus_tag="IXR40_000549"
     CDS             47725..48375
                     /locus_tag="IXR40_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360422.1"
                     /translation="MFIKGGQKMCFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLR
                     AGLITFISIVGFFLFTVIVFIWRTTAPPLPEITYGEFPFSLEYEIDEERILIEDTVIA
                     EFIGSFRGNVTTQPRRSWSIKLLNNSGELKAFHYEFLIIESEDVTITLSSGSAGYFMN
                     DGGSKPQLTVRDRIAGFMHFSHYDLEEARKILAEYGITLINWEYAPPIRNFFNDYY"
     gene            48562..>49123
                     /locus_tag="IXR40_000550"
     CDS             48562..>49123
                     /locus_tag="IXR40_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF443 family protein"
                     /protein_id="HAQ4360423.1"
                     /translation="METVRLWIFMKNFRSALRYVILESKSGYYLIDTDHYTFWGGYLF
                     PIFNWIIPHKVMKINLPAEEINRLILNKDLQRKREKEHSNVAWIGPAFAVVTSSIVGP
                     MLESIYSDFSIGIRYLFVTLSIAVLLCIKGYVSKKNKDILTLIGVNNLSSTKIILFPE
                     SIKEGSRLLIIFIMLILFSVLFGVMFI"
BASE COUNT        16429 a         8418 c        10572 g        13704 t
ORIGIN      
        1 gttagatatt gctataatac ttaagatagt gggaatcttt taagtatagg aggaaaaaga
       61 atgttacgtt tttttccgca aaaaaacaaa tatattcaag aaaaaagcga atttcaattt
      121 aataccgatg gaccaattcc tcagcacatt gccatcatca tggacggcaa tggtcgttgg
      181 gcgcaaaacc gtcgtttgcc acgagttgct ggccataaag aaggcatgga aacagtaaag
      241 aaagtcacaa aaaaagcatc aaggcttgga gtgaaagtgt tgacgcttta tgccttttcg
      301 actgaaaact ggaagcgacc aaaagatgaa gtaagttttc tcatgcaact acctgtcgac
      361 ttctttgata cgttcgtacc agaattgatt aaagaaaatg tcaaagttca tgtcatgggt
      421 tatgaaaacg tattgccaga acatacgcaa gatgctgtaa gacgtgcaat tgagcaaaca
      481 aaaaacaata ctggaatggt attgaatttt gctttgaatt atggaagcag agcagagatc
      541 gtgactgctg tccaagaaat tgccgaagaa gtagcaaaag gagaaataca cgcagaagaa
      601 atcgatgatg aattgattgc taagcattta atgacaggtt tcttgcctaa agagttacaa
      661 gatcctgagc tgatgatccg tacaagtgga gaagagcgaa ttagtaattt tctgttatgg
      721 cagatcgcat atagtgagct gtattttaca aaagcgcttt ggcctgattt tgatggtgcg
      781 catcttgaag aagcaatcgc ctcttatcaa aatcgagacc gtcgattcgg cggtgtaaaa
      841 aaaacagaag atgagaaagg ggatcagtca tgaaacaacg tgtggtcaca gcagccgtgg
      901 cgctagtctt gtttattccg attatatgga tcggaggcat agcggttgag cttacagcag
      961 caatcttagc agtaatagga gtttacgagc tgtttcggat gaaaggattg acactcttaa
     1021 gttttgaagg agttttatcc gccgttggtg cagtgttact tgttttgcca aaagaaagat
     1081 ggtttttctt tcttccagag aatgtaagta catttatgtt attttatctt atagttatga
     1141 ttcttttagg aacatcagtt atttctaaaa atacgtatac gattgatgaa gcaggttttc
     1201 ctgtgcttgt cagcttgtat gtgggaatag gtttccagaa ttttgtcaat gcacgaacag
     1261 aaagcttggc tgttttgata tttggtctat ttattgtttg ggcaactgat atcggagcat
     1321 atatggttgg tcgacgttat ggtcagcata agttaagtcc tgatatttcg cccaacaaaa
     1381 cgattgaagg tgcgctcggt ggtattggta gtgctgttgt agtcgcattt ctttatttat
     1441 tgctataccc agcaaaagaa ctatttaatc atggtatgtt tgtcatgctt ctgatgacga
     1501 ttattttttc agcagtcgga caatttggtg atttggtcga atctgcaatc aaacgtcatt
     1561 atgatgtgaa agactcggga aatatcttac caggccatgg tggaatctta gaccgtttcg
     1621 acagtttgct gtttgtattt cctatcatgc atttatttgg cattatttag taagtatacc
     1681 tgcgtttctt tgtgaatttc ataaaagacg caggttttta tttttcatta tattgatact
     1741 attggtgtct ttggtatact atggtaaaat tatagtgttt tatcgttgtt ttataaaaaa
     1801 cacaaaaaac aagtaaagga gaaaaaagct atgaaaacga ttctgacatt tatcatcgtt
     1861 tttggtatat tagtgattgt tcatgagttt ggtcatttct tctttgcgaa acgatcagga
     1921 atcctcgttc gcgaatttgc tatcggtatg ggtccgaaaa tttatgggca tcaagcaaaa
     1981 gacgggacaa catatacgct tcgcctatta cctattggcg gttatgttcg aatggcaggc
     2041 aatggggatg atgaaacaga aatggcacca ggaatgcctc tttctctttt actaaattct
     2101 gacggcatcg tagagaagat aaatttaagt aagaaaatcc aattgacaaa tgctatcccg
     2161 atggaattga gccgttatga tttagaagat gagctgacta tcactggtta tgtgaatgga
     2221 gacgaaacag aagtagtaac ctaccctgtt gatcacgatg cgacgattat tgaaaacgac
     2281 ggaacagaaa tcagaattgc gccaaaagac gtacagttcc aatcggctaa attgtggcag
     2341 cgtatgctga ccaactttgc tggacccatg aataacttta ttttggcaat cctgttattc
     2401 atcattctgg catttatgca aggtggtgtt caagtgacga acactaatcg cgtaggagag
     2461 atcatgccta atggagctgc ggcagaagca ggcttaaaag aaaatgatga ggtagtcagt
     2521 gtggacggaa aagaaatcca ttcatggaat gatctgacaa cagtcattac gaaaaatccg
     2581 gataaaacat tagactttaa gatcgaacga gaaggtcagg tgcaatctgt cgacgtgaca
     2641 ccgaaatctg tagagtcaaa tggcgaaaaa gttggccaac ttggtataaa agccccaatg
     2701 aatacaggtt ttatggataa gatcattgga gggacgcgtc aagctttcag cggttcattg
     2761 gaaattttca aagccttagg atcactattt acaggtttca gtttagataa attaggcgga
     2821 cctgtcatga tgtaccaatt gtcttcagaa gcagcaaatc aaggtgtaac aactgttatt
     2881 agtttgatgg cgcttctttc aatgaatctc ggaatcgtca atctgcttcc gattcctgcc
     2941 ttagatggcg ggaaattagt cttgaatatt tttgaaggga ttcgcgggaa accattaagt
     3001 caagaaaaag aaggaatatt gacattagct ggctttggat ttttaatgtt gttgatggtg
     3061 ctagttacat ggaacgatat tcaacgattc tttttctaga aaaagttgac aaatagggta
     3121 taataacaaa cgataactat tttgaggaaa taaaggagta tatagaatga gacaatcaaa
     3181 aatgttgatt ccaacattac gcgaagttcc aaatgatgca gaagtattaa gccatcaaat
     3241 cttgctaaga gctggatata tccgccaagt atcagcgggt atttattcat atctgccatt
     3301 agcaaatcgt gtattggaaa aactgaaacg cattatgcgg gaagaatttg aaaaaatcgg
     3361 agcggtagaa atgctgatgc ctgccatctt gccagcagaa ctttgggaag aatccgggcg
     3421 ttacgaaaca tatggaccaa acttgtatcg tttcaaagac cgcaatgatc gaaaaatgat
     3481 ccttggacca actcacgaag aaacttttac tgatttgatg cgtaatgaaa tcaattcata
     3541 taagaaatta cctttaaatc tttatcaaat ccaacctaaa tatcgtgacg aaaaacgacc
     3601 tcgcttcggt ttgcttcgcg gaagagagtt tatcatgaaa gatgcgtatt ctttccatgc
     3661 aacggaagaa agtttggacg agacatataa agattacgaa aaagcctaca ccgaagtatt
     3721 caagcgttgt ggcttagaat ttcgctcgat tatcggagac ggtggcgcaa tgggcgggaa
     3781 agactcaaaa gaattcatgg cgatctcaga aatcggggag gatacgatct gttattcgac
     3841 tgaaagtgat tatgctgcaa acttggagat ggctacaagc tactatgtat caaaaaaatc
     3901 gcatgaaaca cagcttgaat tggagaaagt agctacacct aacgtaaaat caattgacga
     3961 agtagcagat ttcttttctg ttgaacctca aaaaatcatc aagtctgtat tgttcattgc
     4021 ggatgaacaa cctgtccttg ttttggtacg cggagaccat gaagtcaatg acgtaaaact
     4081 gaaaaacttt ttatctgctg actttttaga agaagcaaca gaagaagaag cacaaaaata
     4141 tctaggtgct gagtttggtt ctgtcggacc agtcggtgtt tcagatgacg taaaagtata
     4201 tgcagaccgt tatgtccaag atttagcgaa tgccattact ggagcgaacg aaacaggatt
     4261 ccactataaa aatgtgaatc cagaacgcga tttcactgta ctttcttatg aagatcttcg
     4321 ttttgtacaa gaaggagatc cttcaccaga caacaatggt gttcttgcct ttactcgagg
     4381 aatcgaaatc ggacatatct tcaaaatcgg cactcgttac agtgaatcta tgggagcaac
     4441 tgtactagac gaaaatggac gagaaaaatt tgtgattatg ggctgttatg gtatcggtgt
     4501 aagtcgttta ttatcagcaa tcgtagaaca acattcagat gaacaaggaa tcaactggcc
     4561 aaaaggaatt gcgccatttg atttgcatat cgtccaaatg aatctaaaag acgaatacca
     4621 aacaaacctg acgaatgaac tagaagaagc gatgacaaaa gctggctatg aagtactggt
     4681 tgatgacaga aatgaacgcg caggagtgaa attcgcggat tctgatttga ttggctgtcc
     4741 aatcagaatc actgtcggta aaaaagcagt ggatggaatc gtagaagtga aaatcaagaa
     4801 aactggcgaa atggttgaag tacgtaaaga agaattggtg aatactttac caatcctctt
     4861 gaaccaaggc gaataataag cgttaaaaca cagaaaataa aaatagctga atcagctgtt
     4921 tttgacaatc tgatgattcg cttttaaaat tggaactgcg atttgaatcg cagttccaat
     4981 tttttaatgt aaaactcaga aaaaacgagt atactaaaag gtactgaaaa agaagaggat
     5041 aagatgcgat caattgcatt gtttctcatc agaaagggcg tatatctttg tcagaaaaac
     5101 gagatttatt tgaaaaactg ttggaacaaa tccaactaga ggaagcagaa aaaaatcatc
     5161 cactgcttac tgctggtgaa atggatagtg tagtggtcca tcgtaaatcg cgtttatggg
     5221 aatttacgct gcatttttcc aaaattttgc ctattatgct atatcggtca ttgactcagc
     5281 atctgactat cgcttttaaa gatattgcac aagtcaaact gaatatctta gcagatgacc
     5341 agacattcga tgaacagctc ttgcaagatt actgggccca agctttggaa aatcagcaat
     5401 gcgatacacc actagcacag caagtattga aaacgcaggt acctgtgata aaagatcgta
     5461 aagtcatctt gccaatcgac agtacaggag ctatttctta tttgaagcaa caatacttgc
     5521 cattagtaga agagttgttc gtcagttacg gattcccaaa atttcgtatc gaaccagaag
     5581 tggatgagca gcaagcggaa cgagtattga aactttttga agaacgcaaa caagaacagg
     5641 cagaagcctt tatgaagcaa gcagctgaaa gtctagttgt ccacgaacaa aagaaaaagg
     5701 aaagaaaaga gcaatcgcca gctcttgaag gacccatcca catccagcta ggacgaaata
     5761 ttccagccga tgaaccaacg acaccaatga tcagtatcgt tgaagaagaa cgaagagtca
     5821 cacttgaggg gtacgtattc gacaaagaag tcagagaact acgttcaaaa cgcaagatct
     5881 tgactttgaa aatcacagat tatacttcat catttatcgt caaaaaattc tcgaacggcg
     5941 aaaaagatga acaagtattt gatgcgatca gtgtcggtag ctggttaaag gtacgaggaa
     6001 gtattcaaga agatacgttt gtccgtgatt tggtcatgaa tgcgcaagat atcatagaag
     6061 tcaaacatac acctcgcaaa gattatgctc ctgaagggga aaaacgagta gagcttcatg
     6121 ttcatagcaa tatgagtacg atggatgcaa caaacagcat ctctgatctt gtggcacaag
     6181 cagggaaatg gggacaccga gctatcgcca ttacagacca cggtggtgcg caagcctttc
     6241 cggaagcaca tagtgctgga aaaaaagcag gtgtgaaaat cttatacggc gtggaagcga
     6301 atgtcgtaga tgatggtgtc ccaattgctt ataatgatgc acatgaagca ttgagtgaag
     6361 ccacatatgt cgtatttgac gtggaaacga caggattgtc tgcagtatat gacacgatca
     6421 tcgagctagc cgcagtcaaa atgtataaag gaaatgtgat cgaaagcttt gatgaattta
     6481 tcgatccagg acatcctttg tcacgaacaa cggtagatct gactggtatc acggatggaa
     6541 tggttcgagg atcaaagtcg gaagaagaag tattgcggat gttccttgaa ttttcaaaag
     6601 atacaatttt ggtagcccac aacgcggctt ttgatatggg gttcttgaat actagctacg
     6661 caaggtatgg tattcctgaa gcggccaatc cagtcattga tacgttggaa ttagctagat
     6721 atctgtatcc tcaattcaaa cgtttcggat taggtgtgtt atctaaaaaa tttggtgtca
     6781 gcttggaaca gcatcaccga gcaatctatg atgctgaagc aactggtcac ttagcatgga
     6841 tctttgtgaa agaggcaatg gacaatcata acatgcttta tcatgatcag ctaaatgagc
     6901 atatcggaga aggagattct tacaaaaggg ctcgaccttt ccatgtaacg attttagcaa
     6961 aaaatcaggc aggactgaaa gatttgttca aactgatttc aatgtcgaat gtcgaatact
     7021 tcgaacgcgt cccacgaata ccacgctccc aattgaaaaa gatgcgtgaa aatctattga
     7081 tcggctcagc ttgtgataag ggagaaatat tcgaagccat gatgcaaaaa ggggtagaag
     7141 aggcaagaaa ccgagcaaaa ttctacgatt atattgaagt tatgccaaaa gcggtctatg
     7201 cgcctttgat cgagcaagaa ttggtaaaaa atgaacatga tttggaagaa attatccaaa
     7261 atttggtaga aatcggaaaa agtttggata aaatcgttgt tgcaacaggt aatgtacatt
     7321 atctgaacga agaagatgcc atttaccgaa aaattttgat caattctatg ggcggagcga
     7381 atccgttgaa tcgtcatagt ttgccggatg tccatttccg aacaaccgat gagatgctaa
     7441 ctgcatttca ctttttaggg gaagaaacag cgaaagagat cgtagtagaa aatacgaata
     7501 aaatcgcaga tatctgcgaa gaagtgattc cagtcaaaga tgaactttat acaccgaaga
     7561 ttccaggttc agaagatgaa atatcagaat tgagttacac aaaagcaaaa caaatgtacg
     7621 gagatccgtt acctgagatc attcaaaaac gattaaaaaa agagttgaat tctattaatg
     7681 gtaatggctt ctcggttatt tatctgatcg cccaaaaact agtgcataaa agtaatgaag
     7741 atggctatct agtaggttca cgtggctctg ttggctctag ctttgttgcg acgatgacag
     7801 gaatcactga agttaatccg ttagcccctc attattattg tccagagtgc caatattccg
     7861 agttttttga agatggtacg tatggttctg gatttgacat gccagaaaaa caatgtccaa
     7921 aatgtggtgc acgcttaaac aaagacggtc atgatattcc atttgagaca tttttaggat
     7981 tccatggaga caaagtgccc gatattgatt tgaacttctc aggtgattat caagcagaag
     8041 cccataacta tacgaaagta ttgtttggcg aagactatgt ttaccgtgcc ggaacgattg
     8101 gtacagtcgc cgacaaaaca gcatatggct atgtaaaagg atacgaaagg gacaataatc
     8161 tgcagtttcg aagtgcagaa gtcgacagat tagcaaaagg cgctactgga gtcaaacgga
     8221 caaccggcca gcatccaggg gggatcatcg ttattcccga ttatatggat gtctatgatt
     8281 ttacgccgat ccaatatcca gcagacgatc aaaattcgga atggaaaacg actcattttg
     8341 attttcactc gattcacgat aatgtattga aattagatat tctagggcat gatgacccaa
     8401 ctgttattcg gatgcttcaa gatttatcag ggatcgatcc acaaacgatc cctacggatg
     8461 acccggaagt gatgcggata tttgccggtc ctgaagtact tggagtaagt caggaacaaa
     8521 tttattccaa aacagggaca ttaggtattc cagaattcgg cactcgtttt gttcgaggga
     8581 tgctagaaga aacgcatcct acaacttttg cagaactact gcaaatttcc ggactatctc
     8641 atggtacaga cgtatggtta ggaaatgcgg aagaattgat tcgacgagga gatgcgacac
     8701 tggcggaagt aatcggctgt cgtgatgata ttatggttta tttgatccat gctggattag
     8761 atagcgggat ggcatttaaa atcatggaaa ctgttcgtaa aggacaatgg aacaagatcc
     8821 ctgatgaatt gcgagaaacc tatctatcgg cgatgaaaga aaataatgtg cccgactggt
     8881 atatcgattc ttgttcaaaa atcaaatata tgtttccgaa agcccatgct gcagcttacg
     8941 tattgatggc tcttcgtgtc gcttatttca aggtttattt ccctattttg tattactgtg
     9001 catacttttc tgtacgtgca gacgactttg atctagtctc catgtgcaaa ggaaaagatg
     9061 ctgtgaaaca agcaatgaaa gaaatcacgg acaaaggatt agatgcttcc gtaaaagaaa
     9121 agaatcaact gacagtgctg gagttagcca atgaaatgct ggaacgagga ttcaaatttg
     9181 gaatgattga tttgtataaa tcggatgccg ttaactttgt tattgaaggt gatacgttga
     9241 tcgcaccatt tagagctgtc ccaagtttgg gaaccaacgt ggcaaaacaa atcgttgaag
     9301 caagaaaaga cggtccattt ttatccaaag aagatcttgc cacccgcggt aaagtttcaa
     9361 aaacattgat cgaatatatg aacgacaatg gcgtattgaa agatctacca gatgaaaatc
     9421 aattatcgtt attcgatatg ctataagcat ctgttttcct gtctgcttgt aattttaagc
     9481 agagtatggt atagttctta taggtaatga tactaactgt gagtgagcgg atttttcgct
     9541 cactcttttt aatggaatta cgcacttaat tttttaagga ggcgaaactt ttgagtagcg
     9601 tcgttgaaac agtcacagaa atggtgacac cgattttaga tgaacaaaat tttgaacttg
     9661 tcgaagtcga atttgtaaaa gaaggaaaaa gctggttctt acgagtattt attgacaaag
     9721 aaggcggtat cgatatcgaa gaatgcgcct ttgtcagtga gaaactgagt gaaaaacttg
     9781 atgcagcaga tccagatccg attcctcaag cttatttcct ggaggtatcc tccccgggag
     9841 cagagcggcc attgaaaaaa gaaagcgact atgaaaaggc acttggtgat tatgtccatg
     9901 tctccttata ccaaccagta gatggcgaaa aacaatatga aggatttctt caatcatttg
     9961 atgctgaaca gcttacattg aaaatacgca taaaaacacg agaaaaagaa ttgacttttg
    10021 accgaaaaaa tattgcaaaa gctcgcttag ctatccaatt ttaatcacgg agaggaatca
    10081 gaaaaaatga gtaaagaaat gttaaatgcg ttagacgctt tagaagctga aaaagggatc
    10141 tcaaaagaaa tcgtgatcga tgctttagaa gcagcattgg tttctgcata caaacgtcac
    10201 tatggccaag cacaaaacgt cgaagtggaa tttgatcaga aaaaaggaaa gatccatgtc
    10261 tatgcggtaa aagaagtaac ggaagaagtg atggattcac agttggaagt ctcattgaaa
    10321 gatgcacttt taatcaatcc agcatatgag atcggtgata cgatccgttt tgaagtaaca
    10381 ccaaaagatt ttgggcggat cgctgcgcaa acggctaaac aagttatttt acagcgtgta
    10441 cgtgaagcag aaagaacgat tatttataac gaattcagtg cttatgaaaa agacatcatg
    10501 caaggaatcg tcgaacgcca ggataaacgt tatatttatg tcaatcttgg taaaattgag
    10561 gcagttcttt ctaaacaaga tcaaatgcca aatgaatttt atcaaccaca tgatcgaatc
    10621 aaagtttatg tttcccgagt agaaaatacg tctaaaggtc cgcaagtatt tgttagccgc
    10681 agccatccag acctattgcg ccgcttattt gagcaagaag taccagaagt ctatgatgga
    10741 atcgttgaaa ttgtcagcat cgcccgtgaa gctggcgatc gttcaaaagt ggcagttcgc
    10801 tcaaatgatc caaatatcga tgcagtcggt acatgtgtcg ggccaaaggg acaacgagtt
    10861 caagcaatcg tcaatgaatt aaaaggcgaa aacatggata tcgtcgaatg gaatgaagat
    10921 ccagctgtat tcattgcaaa tgcattgaat cctgcacaag tcatggatgt gatcttcgat
    10981 gagacaaatc caaaggcctg cacagttgtc gttccagact accaattatc gctagcaatc
    11041 ggtaaacgcg gacaaaacgc acgtttagct gctaaattga ctaaccataa aatcgatatc
    11101 aaatcagaat ctgacatgac ggaattttat gaaaatcaag aacaacaaaa agaaacagaa
    11161 gaactgcatg atgaagcaat cgttcagtca gatttaacag acgatgaata tgaaacaatt
    11221 gcattcaaca atgaaacggt cgaagaaaaa ccagaagctt aactttagta aggaggcaaa
    11281 gagatgaaac aaaggaaaat tcctttacgc aaatccgtgg tttcaggtga aatgaaacct
    11341 aaaaaagaga tggtccgaat cacccgttca aaagaagggg aagtatcgat cgatccaact
    11401 ggaaaaatgc ctggacgagg agcgtatgtc tcacttgagc cggaagaagt acaacaagct
    11461 tgggataaaa aaattctcga tcgagtactc gaaacaacat taacagatga gttttatcaa
    11521 gaacttcttg actatgtcac tcaccaaaaa gcacgtaaag agttatttgg aaaatgaata
    11581 cagttaatcg gcaaaaagcc atgaatctca tcggtctagc gatgcgcgcg ggaaaactaa
    11641 tcacgggtga agaactgacc attgctgaaa tccgcaaaca aaaagcaaaa ttggtgtttg
    11701 tggcaaccga tgcaagcgag aatacaagaa aaaagataaa agataagagt tcatattatg
    11761 aagttccttg ctttgagcta ttttctgaag cagaaatcac gcagatgatc ggaaaacctc
    11821 gcaaggtatt cggaataatg gatgccggat ttgcgaagaa gaccaaggag ctaattgaag
    11881 gttaggaagg tgattgcatg ggcaacaaaa gaatctatga attagcaaaa gaactcaaaa
    11941 aatctagtaa agacgtcgtg gaaaaagcac aacaacttgg catcgatgtg aaaaaccata
    12001 tgggtgcgat tactagcaat gatgagaaga aattgcaaca agcgttcaaa aacccaagca
    12061 cgaaacaaca agctgcacaa caagcaagca gaaaaccagc caatcaacag ccgaacgatc
    12121 aacgtaaaaa agaaacaacg aacaatcaac aaaaaaataa aaataaccgc agttatcaag
    12181 atcgcggtca agggagcggt caagtgaatc aaggaaaaaa accaacaaca aaccaaaata
    12241 atacgggaaa taccagcagc caaaatcgtc aaggaacgag ccaaggcggc aatcaaaacc
    12301 gtactaacaa taacaacaaa ccaaacaata acaatcgcgg caaatttaat aataataacc
    12361 gtaatcgtta taataaaaaa ggtaaaaaag gcaaacagca acaatcaact aaaccagctg
    12421 taccaccacg caaattccgt gaattgccag atgtattaga gtatactgaa ggtatgaacg
    12481 tagcagatat tgcgaaaaaa attcatcgtg agccagcaga aatcattaaa aaattattta
    12541 tgcttggtgt catggtcaat caaaaccaag cactggataa agatacgatt gaactgttag
    12601 cgacggacta tggcatggaa ccacaagaaa aagtccaagt tgacattgct gatatcgata
    12661 aattcttcga ggcagaagaa gtcgatccag ataaattagt ctcacgtccg ccagtcgtaa
    12721 cgattatggg acacgtagac catgggaaaa caactttatt ggatacatta cgccattcac
    12781 gtgtaacaag cggcgaagcc ggcggaatca cacagcatat cggtgcctac cagatcgata
    12841 ttgatggtaa accaatcact ttcttggata caccaggaca tgcggccttt acaagtatgc
    12901 gtgcacgtgg agcaagtatc acagatatca cgatcttagt tgttgctgca gatgatggcg
    12961 tcatgccaca aacagttgaa gcaatcaacc atgccaaagc tgcaggcgtt ccaatcatcg
    13021 tcgctgtaaa taaaattgat aaaccaggtg caaaccctca acatgttatg caagaattaa
    13081 gtgagtatga gttaattcct gaagcatggg gtggagaaac gatctttgtt gagatctcag
    13141 cgaaattcgg ccaaaacatc gaagaattgc tggaaatgat cctgttagtc gcagaagtag
    13201 aagatttaaa agcagatcca acacaacgcg caatcggaac agtgatcgaa gcacgtcttg
    13261 ataaaggtaa aggtcctgtg tcaaccttac ttgtccaaga aggaacactt catgttggtg
    13321 acccaatcgt tgtcggtaat acttacggac gtgtccgtgt aatgacaaac gatcttggcc
    13381 gtcgcgataa agaagcagga cctgcaacgc cagtagaaat cactggcttg aatgatgtac
    13441 ctcaagcagg tgaccgtttc gtagtcttcg aagacgaaaa gacagcacgt gcagcgggtg
    13501 aagaacgcgc gaaacgtgca ttattagaaa accgtgctgc cacaagccgt gtgactttgg
    13561 ataacttatt tgaaagcctg aaagaaggcg aattgaaaga agttaacgta atcatcaaag
    13621 cagatgtaca aggttcagca gaagcactgg ctgcatcatt gaagaagatt gatgtggaag
    13681 gtgtccgtgt aaaaatcgtc cattcagctg tcggagcaat caatgaaagt gatgtaacct
    13741 tagcagcagc cagcaacgct attatcatcg gtttcaacgt tcgtcctaca ccgcaggcaa
    13801 aagtgcaagc tgatactgaa gaagtcgata ttcgtcttca ccgtatcatc tataaagcca
    13861 tcgaagaaat cgaaactgcg atgaaaggga tgctagaccc tgaatttgaa gaaaaaatca
    13921 ccggtcaaat gatcgttcgt gaaaccttca aagtttctaa agttggtacg attgcaggtg
    13981 cctatgtaac agaaggatat attcgtagag atagcggtgt ccgtgtaatc cgtgacggaa
    14041 tcgtaatcta tgaaggccaa cttgcaagtc tgaaacgatt caaagatgac gtgaaagaag
    14101 tcaaaatggg ttatgaatgt ggtgcaatga ttgaaaaatt caatgacatc aaagtagatg
    14161 acgtaattga aggatttatc atggaagaag tcaaaaatga ctaaaaactg ataaaaggag
    14221 gccaatcatt atggctaact accgtgaccg ccgagtcggt caagaaatct taaaagaagt
    14281 caatgatatt ttgcgcaaaa aggtccgtga ccctcgtgtg gagaacgtaa cgatcacaga
    14341 tgtgaaagtt acgggggact tacagcaagc aacgatctat tacagcattt tatctgactt
    14401 agcatcagat aagaaaacag cacaagatgg attgaataaa gcatcaggat tgattcgtcg
    14461 agagttaggg cacaatctaa gtatttataa gacacctgaa ttgttctttg aacttgatga
    14521 atcagttgtc tatggcaacc atatcgatga attgcttcgc gacttgaaca aagactaatc
    14581 aaaaactccc gcaaatcctg tgaaatcagg ggttgcggga tttttttgtt ttcattaaga
    14641 cgtattacct aagagttcca tgactttagt cttgcggcgt gtcagctaac caaaaaagag
    14701 aaaaagaaaa gtaaaaaatt cgactttctt ttttctagta gtatataaat ttttgcatat
    14761 agataaagat caagataccg ataacggaag ctagattgta atctatttta gtgacagtca
    14821 ggtatagcca agtaactaga agatcagtgg aacctgcacc ataaaagttt gagtttgtcg
    14881 gtccgttgac agttaaaaga aaaatcacgt tgaagttatt gatatttccg attacgccgc
    14941 ttcgatttgg tcacgatcca aattttggat aatccctgta gaaattagca tagtagctgg
    15001 gataccaatt cacatattga caaagataac agagactttt acataaaacg gatcaatcag
    15061 gaaaggaatt gctcgatcca gccccagttt tccagcaatg tgttaactgg cccagcgtca
    15121 ttcagcaaat tatgcatgat gaggagcgaa atgaactgcg gaacagccat tgtgataacg
    15181 acaagttttt tggatcaatg taaaaaacgt cagcgaaagg aaaaatttcg tggtttttta
    15241 tacctgttca tttggctaga tataaaatcc aaacaaatga acagaagtgc ttattaggtt
    15301 tcaattggga gtatctgcgc tagaataaga gtaataatga aaaggagtgt tatgtatgga
    15361 ttattctagt aaagaatact ttgataaaat gacggcttgg tggcgtgctg ctaattatct
    15421 ttctgttggg caactttatc ttaaagataa ccccttactg agacgtacac tgaaacccga
    15481 agatgtcaaa aaacatccaa tcggtcattg gggaacgatt cctggccaaa attttattta
    15541 tgtccatttg aaccgagtca tcaataaata tgatttgaac atgttttata ttgaagggcc
    15601 aggacacggc ggacaagtca tggtatcgaa tgcttattta gatggaagtt acacagagat
    15661 ctatccagaa gtaacggaag atgagacagg aatgcaaaaa ttattcaaac gattttcatt
    15721 tcctggaggc attgcttctc atgcagcacc agaaacacca ggttctatcc atgaaggcgg
    15781 agagcttgga tactctcttt cacatgcagt cggagctgta ttagacaatc ctgaagtaat
    15841 ctctgctgtc gtgattggtg atggtgaagc agaaaccggt cctttagctg gaagctggtt
    15901 ctcaaatgtc tttatcaatc cagtgataga tggagctgtt ttaccgatcc ttcatttaaa
    15961 tggtgcaaaa atagccaacc caacgatctt ggcacgtaaa tcagatggag aattagcaaa
    16021 ttactttaac ggacttggct gggaaccttt ctttattgaa ggaaatgatt cagaaaaatt
    16081 aaatcctgtt atggctgaaa aaatggatca agcaatcgag aaaattaaat ccatccaaaa
    16141 agaagctcgc ctgaagacag caacagatgt cgtgatgcca aaatggccag tattgatcgt
    16201 acgcacacca aaaggatgga ccggtccaaa agaatgggac ggggaaccaa ttgaaggaac
    16261 cttccgagca caccaagtac cgattcctgt agatcaagaa catatggatc atgcagatgc
    16321 tttactccgt tggctgaaat cctatgaacc agaaaaatta tttgatgcac aaggacgtat
    16381 tttagaagaa atcagagaaa tcgcgcctac tggtgaccaa agaatggcaa aaaatcctat
    16441 caccaatggt ggaatcgatc caagaccgct tattatgcca gattggaaaa aatatacttt
    16501 gcaatttgaa aaaccaggct ccgttaaagc agaagatatg accgaacttg gtaaattcgt
    16561 tcgcgagatc attgagaaaa atccagaaaa tttccgtata tttggaccag atgaaacaaa
    16621 atcaaaccga ttgaatcaag ttttcaaaac gacaaatcgc caatggatgg aaaaaatcga
    16681 accagaaaat gatgaatggc tttcgccatc tggtcgcgtc atcgacagtc aattatcgga
    16741 acaccaagat gaagggttct tagaagggta cgttctgact ggacggcatg gttttttgca
    16801 agttacgaat cattcttgcg agtggttgac tctatgttga ctcagcactt caaatggatg
    16861 cggaaatcac atgacctttc ttggcgaaat gattatcctt cgctaaatct cattgcaagc
    16921 tcaacagtct tccagcaaga tcacaatgga tatagccacc aagatccagg aatattgaca
    16981 catttggcag aaaagaaggc ggagttcatc cgtgaatatc tgcctgcgga tgcaaataca
    17041 ttgctcgcag tcatggataa agcattccgc tcgtcagaaa aaatcaattt gatcatctct
    17101 tccaaacatc cgcgtgctca attttactca gcagaagaag cagccgtctt agtgaatgaa
    17161 ggcttgaaaa tcattgattg ggcttcgaca gcaaaagagg aggaacctga attggtcatt
    17221 gctgctgcag gaacggaatc taacttagaa gcattagcag ctgtaacttt gctgctggaa
    17281 gaattcccaa aactaaaaat tcggttcatc aatgtcgtag atttattgaa attacgtcat
    17341 ccaagtcaag atccgcgtgg gttgagcgat gaagaatttg atcaatattt tacaaaagac
    17401 aaaccgatct tatttgcttt ccacggttat gaaacattgg tccgcacgat tttctttgat
    17461 cgtcataacc atcatttaat gattcatggc tacaaagaaa atggagatat cacgacacca
    17521 tttgacatgc gtgtagtaaa tgaacttgat cgttatcatt tggcaaaaga cgcagcttta
    17581 aaaatcaaag gaagtcaagc agaagatttt gcgaaaaaaa tggatcagaa attacaagaa
    17641 catcaaaact atattcgtga aaatggtatt gatctgccag aagtattgga ttggaaatgg
    17701 aaaaatcttg accaataaaa tgataaaatc gatcccgcaa aatagaattt tttacattga
    17761 ttaagaaact gaaaaaataa ataaaaaaaa cggaaaaaag actggaagaa tggccagtct
    17821 tttttttcgt ttttgggaag tgaaaaccaa actatttacc tgtaagccac ccataaatcc
    17881 aatcaaatgg tgcaaagaaa aaatcttcca ttctattccc tcctttaaaa aagcataaca
    17941 tgatttctat ttacgtgagc atgaattttg ttacgttttt attgccgaaa aataaaaacc
    18001 gttcattatg atgtcaaatt cgtcagtaat tgatgcaatg tgttataata attcagttaa
    18061 atcaaaaatg aaatggagaa aagacatgga cgggttatta cctttatgga aagaacgcgg
    18121 aatgacaagt catgattgcg tattcaaatt aagaaaaatc ttacatacga aaaaaatcgg
    18181 acatgggggt acgcttgacc cagacgtaga cggtgtgttg cccatttgta ttggaaaagc
    18241 cacaaaagtt atcgaatatt tgacagattc tgggaaaatc tatgtaggcg agataactct
    18301 aggtttcagt acaacgacgg aagatcgatc cggagaacgg gtagaaacaa aaccagtaga
    18361 tatgtcttta tctgaaaaaa aaatagatga agtgatggct tcatttattg gtgagatcac
    18421 ccagatacca ccaatgtact cagcggtaaa agtcaacggt aagcggttat atgaatatgc
    18481 ccgcaataat gaaacagtgg agcgtcctgt tagaaaggct cagatttacc gttttatccg
    18541 gacaagtgaa ttgacaagag acgaagtgac aggaaccatt tcttggcgct tcgaagtaga
    18601 atgcgggaaa ggaacctatg tccgcacatt agctgtagat acaggcaaga aacttggtta
    18661 ccctgcgcac atgtctgatc tgacccgaac agcaagtgcc ggtatgtccc agaaggatgc
    18721 tctgacatta gaagaagtag ctcaagctgt gaaaaatggg acaatcgatg attgtttgct
    18781 gccaatagaa aaaggagtgg aacggttcaa acgagtagat attactgatg aagtatggca
    18841 gaaagtaaaa aacggtatga gacttgatta tactgtattt gcgctcccag aaatgccgtc
    18901 agaagaaatt gctttgtttt ataaaggaaa agttgtcagt atttatcagc caaacccgaa
    18961 agaaaaaaac aaattaaaac ctagtaaagt attgagaaat gaggaataac gaatgaatat
    19021 catcaagatc agacatcctt accaatcaga acaaattcca gaagacgatg tcgttttagt
    19081 gctgggattt ttcgacggcg tgcatatcgg acaccagaaa gtcataaaga caggtatgga
    19141 aattgcacaa aaagaaggat tgaaattagc attgatgact ttcaatcagc atccatctat
    19201 tgtctttaaa aagatcgatc ctagcagcgt gaaatatttg actagcctta agcaaaaaga
    19261 agaaaaaatg gccgctttgg gtatagatta tttatatgaa gttgatttta cttcttcttt
    19321 tgctcattta gcaccgcagg aatttgttga tcaatacatc gtagggttac atgcaaaata
    19381 tgctgtttcc ggttttgatt atacgtatgg accaaaagac attgcagatg tcgctcattt
    19441 tcctgaatat gccaaaggaa gattcaaaat cgtcacagtt tctaaagaag aagaacaagg
    19501 tgaaaaaatc agctctaccc gtattcgtgg attactagac agcggacaag taaaagaagc
    19561 agcaaaacta ttaggttgca catatgaggt agaaggggta gttgtccatg gcgatgcacg
    19621 aggcagacta ctaggattcc ctacagcaaa tgtcaaagta aagagcacgg ttcatttgcc
    19681 taaagaaggt gtttatgtgt cggaaataaa aattggggaa acatggtatc cagccatggg
    19741 ttcaattgga cataatgata cattcggtga aggacgggag ctgactgtag agttgtatat
    19801 tttggacttt aatcaagata tctatggtga acatgtcgcg gtacgctgga atcaattttt
    19861 aagagatcaa gtgaaatttt ctagtgtaga ggaattgatt gaacaactca aggaggatga
    19921 acaagcaaca gctgaatatt tttctcagca ataaaacatt atgcataaaa tctcttgttt
    19981 atgtataact agcaattaca ataaaatggg tgataaataa gcccaggaaa ggggctgtga
    20041 caaaagtctt gtcacagcct ttttttccaa ataaatggtt tttcagaagt agcttcttcg
    20101 gaaataagcc gaaatttctt gaagctgacc acttctgtca caacctcttt ctttatagaa
    20161 ataaaaggac actagcaatt catgaaaacg attgctagag cgtatcattt gctttagact
    20221 atatatcttg gtgtacactc actttaaggc ggaaataaaa gttatccgta ataacaggtt
    20281 taggtatgaa aaaggagtgg gtactatgta caaggaatta gaaaacaaag tcgcagtagt
    20341 aactggtggc tcaaagggga ttggaacagc gattgctcaa cgattcggga aagaaaaaat
    20401 gaatgtagtt gtcaactata actcggataa agaaggagca gaaaaagcag tcaaagcaat
    20461 cgaagaggca ggcggaaaag cagtctctgt acaagcagat gtcagttctg aagaaggaat
    20521 acagcgttta cttgatacgg ctttagaaaa ttttgggaca ctggacgttt gggttaataa
    20581 tgctgggatg gaaaatcagc atccaaccca tgaacttagc cttgaagatt gggaaagagt
    20641 gttaaaagtc aatttgactg gcgtttttat cggaacgaaa gcggctttaa attactttac
    20701 agagaataat aaaaaaggaa atatcatcaa tatgtcttct gttcatgaac agatcccatg
    20761 gccaacgttt gctcattacg ctgcttcaaa aggcggggta aaattattta ccgaaacggt
    20821 agcaatggag tatgcaccga agggaatcag aatcaatagt ataggccctg gtgctatccg
    20881 tacacctatt aatgcggcaa aatttgatga tcctgaacaa aaagaactct tggaaagtat
    20941 gatcccacta ggacgcgtag gtgaaccaaa agaaatagcg gcgacagctg catggttggc
    21001 ttcagacgaa tccagttatg ttacaggtat tacactattt gcagatggtg ggatgacttt
    21061 atatccttct ttccaaggtg gaaaaggata agggtgaata aaaatgggtt tattgattgc
    21121 attgatcccg gcagttggct gggggatcca gccactgatt ttgaaaaaga ttggtggcag
    21181 accaacaaat gagatattag gaactggtat tggagcggtg cttgtcggct tactcgttca
    21241 attattcgct tctccagctg gtatttcagt gactacattt ttgattagtt tactttctgg
    21301 tgcattttgg gttattggac aaacaggaca gtatacatct ttcaacttga ttggtgtttc
    21361 taaaacgatg ccaatttcga ctgcattaca gttagtcgga acctcgttga ttggtgtctt
    21421 cgcttttgga gaatggtctg gaagtatggg gaaaatcatt ggagcagcag caatcattct
    21481 tcttgtattt ggttctgctt taacggcaat cagtgatgat cctggaaaaa aaggcggtat
    21541 cacaaaagga attagtctat tagcatcaac aagtattggt tattgggtat acagtgcatt
    21601 gcctaaacta gttgatgcaa gcggactttc cattttcttt ccgcaaatga tcggtgtctt
    21661 tttaggggca gtgatttatg tgattttccg taaaccaacc gcattttctg aagacaagag
    21721 ttggaaagca acgatcgttg gagccatctt tagtgtgtca gcattggctt atattttttc
    21781 agcaaatgaa aatggggttg ctactgcata tatcattaca cagctaaacg tagttatctc
    21841 tacattaggc ggtatgtaca tcctgcatga aaataagaca ccaaaagaaa aaaaattaac
    21901 gattatcgga ttattgctga tcgtagtagg aagcatggtc acggtcttta tttgaggata
    21961 aagatggtaa aatttcattt attaaaaaaa tatttgtttg aaccaaacag taagtactta
    22021 taaaaaaata gcgctagaat ttccaacatc tctggaattt ctagcgcttt ttaattgttt
    22081 aagatacaag ggaaatatct gtctggatca ataatttttc attgatccat tgactaaagt
    22141 ttacgacata attgaagtta ccaccgatta gtatctccgc atgattgtct ttataaagat
    22201 cgtattgtaa aagacggtct tttttatttg cgtaaacatc gttatggtac tggactaatt
    22261 gttctcggaa ttgattgatt gctgtaaaat cacgatattg aaggttgaaa cgcatcgtga
    22321 ttggtgcatt tagcatgaat cgctgcattt cttttgctgc ttcctctgct tgatctccgt
    22381 ataggaactc aaaaagatta cgttcagaaa atttccattg cccgccaacc tttgttcctt
    22441 ttagttttcc ttcatgaaga taatttctga tagaacgtgt agtaacacct aattgttcgg
    22501 ctaattcatt tactgagtaa aaatctttca atgttcaccc tcctatgtga atggttctac
    22561 tgacttagtt gatatttgct taatcacgaa atgtagaaag aacgatttta attaaggtca
    22621 ttgtaaaaat caagtcagaa aattctaact tttatttctc taaagaaatt cgttctctcc
    22681 taaagtgata ttatatttaa atatacctga aaataatggg cagtattatg aaagatcact
    22741 gatattttct cgtatttttt ccttattcaa aagttttgca ggaaaattgc tgaaaaaata
    22801 attttactaa gtagaaaatt caaagccatt caatcagtga tttttttcag cacaagaaag
    22861 actccttata aaaatagcag atactttgtc aattaagtgt ttaaccaggg atgataaaaa
    22921 ggataggatt gaacaaaacc tgtataaggt gatgaatagt ttcctcgcca gtaaaaggtt
    22981 tattcgtata aagctttatc gccaaaattt atcatgacct tttttatctt caatattaaa
    23041 tgaaatcaat tgttcaatca attcccagtt gattacactt ttccaaggaa ctttgatgac
    23101 gttatccgta tatacgtagc ctgcttcttg gatatttttt tcaagggcac gaatcgctgc
    23161 tttttccggt gcgatagaaa aatgattttt agcaaaacta aatgcaataa taaaggtacc
    23221 atggtcagta aacataggtt ggttccattt tacagttgtg tctagctggg gatacgtttc
    23281 tgttatctta gcaaaaaggt ctttgatctt ttgttgatgt tctttttctt tgatttgatt
    23341 gatgatcggc tgaaattttt ccattctaaa acgcctccat taagtggttt gatttatttt
    23401 accagaaaaa caatagttat gtataaaaaa cgaacaaaac acaagtaatg ttgtaaccgc
    23461 tatatttata tgataagatg tctcaaataa taaaatagaa aagagacata aaaatgattg
    23521 acttggcaaa gaaattctta cacgaaaata tatattttga gttgtatcat catcgagcca
    23581 tttatacaaa tgaagatgct ttggtaataa agaaagaaca aggatttaca ggtacagaga
    23641 ccaaaagctt attcttaaaa gataaaaaag ataataacta cgtatatctg acttttacta
    23701 cgaaacaaac ggatttcaaa gcattaggga agatcgtcgg taaaaggctt tctattgttt
    23761 catcagaacg catggaagaa caaacgggac aaaagcaggg cgctgtttct ccgtttggtt
    23821 atgaaaaaca gattccgatt attattgatg aagagctctt atcaaatgaa aaacttgttt
    23881 ttgcaccagg tagaccagat caaacgatgg tcatccaaac ggttgactta aacaaaatca
    23941 tccagctact tgagatgccg atatttttga tgccggcaaa cgaaaaaaac aattaaccaa
    24001 gtaaaatagt gcatacttgg aggtgaagca acatgataag ttatccatta ttagaaagaa
    24061 atgcaacgat tggggttact gcaccatcct caggcgtatc agaggaacac cattcgttac
    24121 tcgaatcagc tttaaagaga atggaagaaa aatctttcca agtagttact ggaaagacgc
    24181 tttggacgca agataaggaa aaatcaggtc cagcaagaaa acgagcagat gaattcaatc
    24241 aaatgatgca agatgaaaat atccaaatga tctttccgac ttggggagga gaattattga
    24301 ttgagattct cgattttgtc gattttgatg ctctacaacc aaaatggata gtaggttatt
    24361 cagatattag tacgttgcta cttgctgtca cattaaaaac agggatagcc actgcacatg
    24421 gaactaacct tattgattta agaggagagt acttggatga aacgacagca atgtgggaaa
    24481 gtgtactgaa aacaagagaa ggagaatcga ttctacagca atcttctgaa aagtatcaaa
    24541 aagtgtggcc ccatgagcat tcatcatctt ctgttttcca tctcactgaa ccaacaaatt
    24601 ggcaatcagt cagcggagat gcagtaagga tgaagggacg attattaggt ggttgtattg
    24661 atacgatcag gcatttaatc ggtactcctt atggagatgt ccaatctttt aaaagaaagt
    24721 ataatgatgg aaagccgatc ttgtggtttc tagaaaactg tgagctatcg tcagttgatt
    24781 taagaagatc acttgttcag atgaaactgg caggctggtt tgatggcagc tcggggatca
    24841 tgttcggtag aagtgcggca gaggatttgt tagattataa aatgaaggat gtatacgaag
    24901 atctgtcaaa ggaattaaaa ctaccgatct tgtatgatat tgattgtggt catgtaccgc
    24961 cacaactgac attgattaat ggtgcctatg cagaagtagc ggtagaagat agaaaagcga
    25021 ctgttttgca aacgtttatt taaaaaattt tttcctgcct tggagtctat caaagaccaa
    25081 taaatctaaa tagaaaagaa agtgaaagaa gctgacaaaa tgctgtcagc ttctttttgt
    25141 ataacatatt agaaagtcta attatctata actgtcacat cgattaactg tttcacgtca
    25201 ttgggatttc ctgtaggaat agctactaca gatgcattat caatgatttc ttgagttgtt
    25261 tctctaatga acgctggata agatgtttga tctgcaggca tttgccaatg tgaaggaact
    25321 ggataactag tgattgtccc gtcatggtta cttgaataca ctaaaactcc ctggtaactg
    25381 tatttcccag tgagcataac cacatctttc ggatagactg cactccctgc atcataaggg
    25441 gcgataggtg ttcctgcagg ataatgaata acatgtaatt cgaaatcacc cgatgtatct
    25501 ctaaaagtat tacctctaat agctagccaa acacgtgcgt actcaatttg tagatcagaa
    25561 tatcctgcta acggatctat tgactgagaa gactgtgagg aggttgtgtc tattgttgaa
    25621 gaagaaatat ttgtctcaac tgtactacta gatgtagaag aagtattggg ctctgagact
    25681 ttactgcttg ttgaagatgt attcgtttca gtagaagctg atttctgagt acttgatttt
    25741 tcagctgaac tggtttgtct gattgaactt ttgtctgtgg tcgcagatgg atcactattt
    25801 tctttactag gagacgtaca tcctacaagg aataaagaga ccaacaataa aataaaacct
    25861 aactttttca tataaaatac ctcattattt ttttaatacc agtatagcat aatcctgaat
    25921 ttttgaatcc gtaaaacctt gtctatgaat ataaatagag tgtatcttct ttgataaatg
    25981 tcagaaaaag tgtgacaaat aatcatcagt aaaattactt gtcacactat tgataaggag
    26041 tatttaattg aagagaatga ttaggagaaa ggatctccgt actttttata gtaatcatag
    26101 aatccaagtt tgtatagacg aatcgttttt tctcttattt cttctgtttc aaaatggact
    26161 gcttgaagaa tcaagtctgt gaattctata ggagctgttc cattcgcagt aatcaaatta
    26221 cgatctttca cagcttgttg ttctataaaa tcttctttat tctgataatt ttccgattct
    26281 aaccaaggaa attgcgcatt tccggtgtgt ttgtaacctt gcaataatcc gctctgagct
    26341 aaataatcaa ctgccccaca aatagcagct actggtacgt ctgtttttaa caatttatcg
    26401 attatttgat ataaatgatg attttttatg tcccatgaat tgccaccgat cataataaaa
    26461 aggtcaactt tttcaggtat ttgttcgatt aagtaatcga tttttgtttt taatcctcca
    26521 atggaagtga cctctgattg gatagaagca gttttgtttt gccatttctc attttggttt
    26581 agtgtgctag taatataagc accttcccaa tcggcatatt cctctaatag aaacgtaatc
    26641 gcagttttca ttttcaagct ctcctttact atctataaca aggacaacag ttttaaccta
    26701 cagacattca ttaaaattgg gtagcgacag cgaaaacaac aattcttaag ttttagacag
    26761 agtatacaga tagtcaactt aattaaatac gaactaaata aaaatgacag gtaatcattt
    26821 ttgtttacca gcattataac attttgcata catggatgac aaaagaacca attcccactt
    26881 gcttgagtac aatattaaaa gaaactggaa ggcaaaaagt aattatagaa acgaaaaata
    26941 aatcatatcg ggcactcaga catgaaaaca accctagaga tatataacta ggtaaccagt
    27001 ttaatgaaag aaaaaatcat ccaagaagtc gattcttgga ttttttagtg gatttgttcg
    27061 ccaaatacgt ttagtatgcg tatatgagag gttgtaagca aagcgttgtg gtctgagcac
    27121 ttaaggagga atctgtgaaa atagcttttc atatttttgc agattttgac ttaatgccga
    27181 aggtcagctt tgcgattacc gtttatcgag aggctgtaaa agcaccgtgt agctccgatg
    27241 acaataagca agcattttta gagctaggtt tccttgattc taaatatgcg gcttatttca
    27301 atgagttggt gcttgaacgc gattttaaga aggtcgaaaa caggcacgac ttttcgacgt
    27361 aaggagaaag aatttcaatg atagaaacaa taaatcccgc agaaaacaag gtttctgcgt
    27421 acattcatat cccattttgc gagcatatct gctattactg tgattttaat aaagtttttt
    27481 tagaagggca gccagtagat gagtatgtgg aaatgctgct gaatgaaatg aaaataatgc
    27541 tagaaagtca tccgacagcg aatttagaaa cactttacgt agggggcggg acaccaactt
    27601 ctttatctgc taaacaactt gatcgactgt tatcaggtgc tagagagatc ctgccttttc
    27661 aaaatggtaa tgagtttact gtagaagcga atccaggtga tttgacccgt gaaaaacttc
    27721 aagtaatgaa aaactatggc gtcaatcgtt tatccatggg agtgcagaca tttgataatc
    27781 gcttattgaa aaaaattgga cgtaaacaca ccgcagaaga tgtgtatcaa actatgcaat
    27841 ttttagaagc agaaaatttt accaatgtaa gcatcgattt gatttatgca ttaccgggac
    27901 aaacactaga aggatatctg gatactttgg aaaaagcttt ggctttggat ctgcctcact
    27961 attctttgta ctcattgatc ctcgaaaaca aaacaatgtt catgaactgg gtacgacaag
    28021 gaagactcga actgcctgat caggaaacgg aaaccagaat gtttgaagag acgattgaag
    28081 caatggaaaa gcatggacgt caccaatatg aaataagtaa ctttgggctc tccggacatg
    28141 aatctcaaca taacctcatg tactggaaca atgcccacta ttttgggttt ggagctggtg
    28201 ctagcggtta tcttggagat attcgttacc gcaacaaagg accaatccaa cactatttac
    28261 gcccattacg agcaaatgaa cgcccggtat tggaagaaga aaaattgaca cgaaaaaatc
    28321 aaatagaaga agaaatgttc ttaggactaa gaaaaaaaac agggattact aaaaaacatt
    28381 tctatgatcg ctatcaaaaa acaattgaat cggtgtacgg tgatgtgcta agggaattag
    28441 agcaagaagg gttacttgtt aatgaagaag accgtgttta tttgacacca agagggacct
    28501 ttttggggaa caatgtgttt gagcgctttt tgtttgaaaa atagtttaaa gaatatttgt
    28561 tttttatctg aatttaaata aaaaaagttc aaaaatacaa taaaggacta ttgaaacgtt
    28621 gatataactg gatttacatc aattatttag aattagcact cttgtgttta gagtgctaaa
    28681 aaatggagtc tttctcttga caggagaagg gcttcttgct atatttataa gtggattagc
    28741 acttagaata tatgagtgct aatgagaggt gaggaagatg ttaacaaagc gacaaaacga
    28801 cattttacgt ctgatcatcc aacactatac gagtagtggc gtgcccgttg gttccaaaac
    28861 attgatgtct gagggagtca aggccagctc agcaacgatt cgcaatgata tgaaagcatt
    28921 agaagatgaa ggattgctgt tgaagactca ctcttcttct gggcggattc catctgcttt
    28981 aggctatcgt tattacgtgg atcatttgtt aaaacctgct cgcgtagcag aagatgattt
    29041 gctgctgatt cgtcagtctc taggcagaga atttcatgaa atcaatgaga ttattaagca
    29101 atctgctgag atattatctg agctgacaag ctatacgact ttttcattgg gacctgaaat
    29161 aaaagaccgc cgactgactg gctttcgtat cgtacccttg aataatcgac agattattgc
    29221 tatcgtcgta acagatatgg ggaatgtaga aagccaagtg ttcactcttc ccgaatatat
    29281 gggaagtcag gaactagaaa aaatggtaca gattgtaaac gaccgtctag tcggagatcc
    29341 tctgatgacg gtgtaccata aacttcgtac ggagattccg atgattcttc ataaatattt
    29401 ccaaacgaca gaagggatgt ctcagttatt tgacaccgtt cttggtcatg tttttgaaga
    29461 taaggtttat gtcagtggac aaatgaatct cttggattat gagccccgtc aagatcttga
    29521 tcagttcaaa tcgatgtttt cttttatgaa agactcagac ggacttacac aaatgatcac
    29581 tccgatggat agcaatattc atatcaagat tggtgctgaa ttaggcaatg atttattgca
    29641 gaatatgagt atgattcaag caagttacga gatagatggt catggaagag gtacaatagc
    29701 cttgttaggg cctactagta tgccttattc tcggatgttc ggtctagtcg atgtttatcg
    29761 aagagaacta gcagctaaac ttgctgatta ctaccgttcg cttgacttgt caaactcgta
    29821 atgtgaataa cgaagctatt tgcagctgat cgttctctct ttcttagtaa gagcaatcaa
    29881 acagctgact gaataatgaa aggaagactg tatcgtgaaa gaaaatcaag aagaactaga
    29941 taaagaaatg acagatgctc agccagaacc ggaaatcgat gtcgaagctg cagaagattc
    30001 gggtatttca gaagctgaag cggaagaatt cgaaacagcg aaattaaaag ctgagttaga
    30061 agaaatggaa gataaatact tgcgggctcg tgctgaaatc gcaaatatgg caaatcgagg
    30121 aaaaaatgag cgtgagcaat tacaaaaata ccgttcacaa gatttagcca aaaaattact
    30181 tccatcaatt gacaacctgg aacgtgcatt agccacagaa gtgtcagatg atcaaggggc
    30241 aggtttgaaa aaaggcgtgg aaatggtctt ggaaagtttg cgtaacgcac tggaagaaga
    30301 aggaattgaa aaaatccctg ctaaaggaga agcctttgat cctaatcttc atcaagcagt
    30361 acaaactgtt ccagcgactg aagatacacc agccgatacg attgtagaag tactacaaga
    30421 aggctacaaa ttacatgatc gcgtgttaag accaaccatg gtcattgttg cacaataatt
    30481 gtgcggatat aaaacttaca ctttcaatta aagaaggaga cgttaattat gagtaaaatt
    30541 atcggtattg acttaggtac gactaactct gcagtagcag tattggaagg aaacgaagca
    30601 aaaatcatcg ctaacccaga aggaaaccgt acaacacctt ctgttgtatc attcaaaaat
    30661 ggagaaatcc aagtagggga agttgcaaaa cgtcaagctg tgacaaaccc aaatacgatt
    30721 tcatcaatca aacgccatat cggtgaagca ggttacaaag tagatgtaga aggtaaatca
    30781 tatacaccac aagaaatctc agcaatgatc cttcaatata tcaaaggatt cgcagaagac
    30841 tatttaggtg aaaaagtcga aaaagcagtt atcactgtgc cagcttactt taatgatgca
    30901 caacgtcaag caacaaaaga tgctggtaag atcgctggtc tagaagtaga acgtatcgtc
    30961 aatgaaccaa ctgcagctgc tcttgcctat ggtttagata aaacagatcg cgacgaaaaa
    31021 atcttagtat tcgaccttgg tggcggtact tttgacgtat ctatccttga actaggagac
    31081 ggtgtctttg atgtattgtc aacagctggc gacaaccatc taggtgggga cgactttgat
    31141 aacaaaatca tcgactacat ggtagcagaa ttcaaaaaag aaaacagcat tgacttgtct
    31201 caagacaaaa tggctttaca acgcttgaaa gacgctgctg aaaaagcgaa aaaagattta
    31261 tctggcgtat caagcacaca aatcagcttg ccatttatca cagcaggaga atctggacca
    31321 ttgcatttgg aaatgacatt gacacgtgca aaatttgatg aattaacagc tgacttagta
    31381 gaacgtacaa aagtaccagt acgtcaagcg ctaaaagatg caggtttatc acaatcagaa
    31441 atcgacgaag ttattttagt cggtggatct actcgtatcc ctgcagttgt agaagcagta
    31501 cgtaaagaaa caggaaaaga accaaacaaa tcagttaacc ctgatgaagt agttgctatg
    31561 ggtgctgcta tccaaggtgg cgtgatcact ggtgatgtga aagatgttgt tttacttgac
    31621 gttacaccat tgtcattagg tatcgaaaca atgggtggag tgttcactaa attgattgac
    31681 cgcaatacaa cgattccaac aagtaaatca caagtattct caactgcggc agataatcaa
    31741 ccagcagtag acatccatgt attacaaggt gaacgcccaa tggctgctga caacaaaact
    31801 ctaggaagat tccaattgac agatattcca gcagctcctc gtggtattcc acaaatcgaa
    31861 gtaacattcg atattgataa aaacgggatt gtaaatgtat ctgcgaaaga tctaggtaca
    31921 caaaaagaac aaaaaatcac gatcaaatct tcttcaggtc taacagacga agaaatcgaa
    31981 cgtatggtaa aagatgcaga agcaaatgca gaagcagata aagctcgtaa agaggaagtt
    32041 gacctacgta atgatgtaga tgcattgcta ttctctgtgg acaaaacatt gaaagaatta
    32101 gaaggcaaag tggacgaaga agaagtgaaa aaagcagaaa cagctcgcga tgaattgaaa
    32161 gccgctgttg aagcaaacaa catcgaagaa atgaaaacta aacgcgatgc attgaacgaa
    32221 atcgttcaaa acttgactgt taaactatac gaacaagcgg cacaacaaca agctcaagaa
    32281 aacccagaag cagctcaagg cggagcagat gatgtcgttg atgctgattt tgaagaagtc
    32341 gatggcgacg ataaataatc agttcactga atttcgagag aaggccaaag ttgctacttt
    32401 ggctttttct tttgaaaaat agtttgaagt atcggttttt gtttcaaaca aaatatgata
    32461 tgataacaag cgacgtgaaa atgatgagaa ccaataggag gaaagcctat ggcaacaaaa
    32521 cgtgattatt atgaagtctt agggctctca aaaggagcat cagaagatga aataaagaaa
    32581 gcttatcgta agctttcgaa aaaataccat cctgacatca ataaagaacc tgatgcggaa
    32641 gaaaaattca aagaagtatc agaagcatat gagattttaa gtgacccgca aaaacgcgct
    32701 gcatatgacc aatacgggca tgcaggcaca gatccaaatt acggtgctgg tggagctggt
    32761 ggcggatttg gtggattcgg cggcttctct ggtggcggct tcggtggttt tgaagatatc
    32821 ttcgactctt tctttggagg aggcggtcgg tcagtcgatc caaatgcgcc tcgtcaaggt
    32881 gctgatttgc aatatacggt cgacttgtct tttgaagaag cgatttttgg tgtagaaaaa
    32941 gaaatcaagt ataatcggga agaaatctgt catacttgtg gtgggaacgg tgcaaaacca
    33001 ggcacacaac caactacttg tcataaatgt catggtgcag gtacgattaa tgtagaacgc
    33061 caaacaccac ttggacgagt gatgagccgt caaacttgtg atgtttgtca tgggacaggg
    33121 aaagaaatca aagaaccttg tccaacctgt catggctcag gacatgagaa gaaagcacat
    33181 tcagttaaag tgaatgtacc agctggtgta gaagaaggac aacaaatgcg tttagctggt
    33241 caaggagaag ctggagaaaa cggcggacca tttggtgatt tgtatgtggt cttccgtgta
    33301 gaagaaagtg atatctttga tcgtgaaggt tctgaaattt actatgaatt gcctttaagt
    33361 tttgtacaag cagctttggg ggatgaagtc caagtaccaa ctgtccatgg agatgtgaaa
    33421 ttgaagatcc ctgctggaac acagacaggt acgaacttcc gtttacgtgg aaaaggcgct
    33481 ccgaagttac gtggtggtgc aacaggcgac caacatgtca aagtaaaact gatcacaccg
    33541 aaaaatctaa atgaacaaca aagagaagca ttacgtgcat tcgctgaagc tggcggcatc
    33601 aaagttgaag aacagcaaga agacggtttc ttcgataagt ttaaagatgc ttttggcggg
    33661 aaaaagcgga agtagttttt ctagtaaaaa cgctaagtca ttaataatta aaaaccagac
    33721 gaacaatcat atgttcgcct ggtttttttg tagttgtcat gtttgtacca acaaaaaagc
    33781 cagctttaga atatgataat cgtcatagtt tctaggggta taaccagtga gagaatggaa
    33841 cttgttcaat cgatattgca aggtgttttt atgaataaat aattcttctg agcaattttt
    33901 gatgcttccg ttatttttac tgaagcatgc caaagtcttc ttgaacaaat gtacttcttc
    33961 ttctgtcagg cttttcaaaa tacgttttac atataatgtt cgttgatctg acgggattgc
    34021 tggtaaaacg atcccgaggt ctaaatcttc aaaaaagcgg atctcgttca cagattgatg
    34081 gaaagctatc cattcgcaaa cttgtttggc atgaaggaaa gattgcggtg tctcttgctc
    34141 tgtataacaa agcgacccaa ttccaaagtt tagctgtaac tgatacattt tattaaactt
    34201 tgtctggatt ttatcaagca atgatagcaa tgaggctctg gaaatccgat tgactaggat
    34261 aatgatttgt tgtctatgta cagtgagcaa agcctgtccg taataagaga agaccctttc
    34321 gagcaactcc aataaaggat tgatccgttc ttgacacaat tgctgattgt cagaaagttg
    34381 tcccacaact acataatatg gagaagaaaa atcaagctca attaagtgag ggtggtatcg
    34441 actatgtact tgatatcatc aatgaaccga tggtactttc ttatgcgatg gaacaggtag
    34501 agcgattgct tgtttgtgca ggaaaacaag cgatgcggct gatacgatta ggtgagaaaa
    34561 taagaagata aaaatacacg gtcccttcat ggcgaccgtg catttttggt ttttattaaa
    34621 tatttaatac tttattcaag aaatcttttg tccgttcatt ttgcggattt tcaaagattt
    34681 gttgaggcgt tccatcttct aaaaagtttc cgtcgtcaat gaacatgacg cgattggcca
    34741 cttctttagc gaaccccatt tcgtgcgtaa cgataaccat cgtcatacct tgttctgcta
    34801 actttttcat gacgttcaag acatcaccga ccatttcagg atcgagtgca gaagtaggct
    34861 catcaaaaag catgatgtca gggttcatcg ctagagcacg agcaatagcc acacgctgtt
    34921 tttgtccacc agaaagcatt tcaggataca tatctttttt atcttctaga ccaactgtct
    34981 gcagtaattt gattgctttt ttctctgctt cttctctaga ttctttcttc aggtccatcg
    35041 gtgctaaaat gatgttttcc aaaatagaaa gatgagggaa taggttaaag tgttggaata
    35101 ccattccgat atgttgtctc accaagttga tatctgtgct tttatccatc aagtgggcgc
    35161 cgtcaataat aatttcaccg tcagaaggtt cttctaaacg attcaagcaa cgcaagaatg
    35221 tactttttcc tgaacctgaa gggccaatga tacagacgac atctccttcg ttgatggata
    35281 cattgatgtc gtttaatact gtgttatcgc cgtatttttt gactaaatgc tcaactaaga
    35341 ttttttctgc catcttactt caccttcttt tctaaaactt ttgctaattt tgtcaatgct
    35401 gtgatcaaaa tcaagtacat gatcgcaatg atcaagtaaa catacgtact ttgtgttgta
    35461 cgtgcaacaa tgatcttacc agtttgcagc aattcgacta caccgattgc ggaaatgatc
    35521 gttgtgtctt ttaatgagat aacgaactga ttgacgaatg atgggatcat gatgcgtatc
    35581 gcttgcggca aaatgatttt ttgcattgtc cgattataag aaagacctaa acttctggaa
    35641 gcttccattt gtccgacagg aacggcgttg atcccgcctc gaacaatctc tgcgatataa
    35701 gcacttgcgt taagagtcaa ggtgataaca ccagcaagga agtcaggaat cgtaaatcca
    35761 acgataccag gcaacccaaa gaaaataaag aacgcaagaa ccatcattgg aattcctcgg
    35821 atgatatcga cataaatact agcaattgtg cgaagagcgc gtattggtgc tacactgaat
    35881 aatccaaaaa tcacaccgat tactatagcc aaagcaaagg agatcaaagt taggagaatt
    35941 gttctccaaa gtcctttcaa caatgcttga tagttgtttt ggataagtcc aagaaatgtt
    36001 gattcatcag cagtggaaga ctcactggaa gtttctgaac catccgctac atattcttta
    36061 ataatcttat cgtattcgcc tgttcttttt aattctttca atccttcatt gaacatatta
    36121 agaagctcag gattttgtcc ttttttaacg gcaaatgcat attttccgcc agattctttt
    36181 ttgatcggtg tttccaattc ttgtccttgt ttgatcgcat aaccgattac cggataatca
    36241 tccatcattg catcgattgc gccaactttt aacccgtcgt acaattgatc agcagcatca
    36301 aaatatttga tagaatagcc atattcagat tcatggtcgc ttaaaaattc agcactttcg
    36361 gtaccaactt ttgctccgac tgtttttcct ttcaaatctt cataagactt gatcgaagta
    36421 tctccttttt tgacagctaa ttggatcccg ctatcaaagt aagaatcaga aaaatcatag
    36481 cttttctttc gttcatctgt tacagtcatt ccggcaatca ttccgtctgc ttgtcctgat
    36541 tccaaagctt gcaaagcagc agagaaacca cggtagtcca ttcggatgtt aaatccttgc
    36601 agtttggcga tgttttccat caattttaca tcgatgcctt cgtactcgcc ctttgcgttt
    36661 tgaaattcaa atggagcaaa agcagagtca ctggcaatta cgtatacgtc ttttttgggc
    36721 tctatttttt gcattgtctc gcttgtgctt gactctgccg ttgtagtgtt gtcagcttgt
    36781 gcaacatgac caaacgcaag tgtcacaagt cctgtcatta agaaaacaaa tgagtgaaat
    36841 aaatgctttc ttttcataat caacctccta aatttccaat attttattat tataggcgaa
    36901 aagtgctgaa tcagacaaga ctgtaagctc gaaaaaatga aaaaaatgcg agtttctaac
    36961 attttatgtt ataaaacata acatgtataa taagataaaa aagtggcgaa agtatgttcg
    37021 gtgtggtata attttttagt aaggaatgcc tttgctttcc ttttcttttt attggtcgta
    37081 aaatgaaaag gaatgaatga aaaggaggac gaagaatgat tgagagagat acctcccgac
    37141 actttgagct tgtctcgaaa taccaaccgg ctggtgatca gcctgaagcg attaaccaat
    37201 tagtggatgg cgtagtcggc gggaaaaaag cacaaatctt attaggtgcg actggaacag
    37261 ggaaaacata tacgatttcc aatcttattg agaaagtgaa taaaccaaca ctgattattg
    37321 cccataacaa aacattggct ggtcagctgt acggggaatt caaggaattt ttccctaaca
    37381 atgctgttga atattttgtt tcttattatg attattatca gcctgaagct tatgtgcctt
    37441 caagcgatac gtatatcgaa aaagattcaa gtgtaaatga tgagatcgac aaattacgac
    37501 attcggctac tagttcatta ttagaaagaa atgatgtgat cgtcattgca tccgtttcat
    37561 gtatttttgg attaggctcg ccttttgagt accaaaaaca agtagtttcg attcgacagg
    37621 gagcagaact agatcgcaat cagttgattc gtgacttagt cagtatccaa ttcgaaagaa
    37681 atgatataga ttttcagcgc ggtcgttttc gagtgcgcgg tgatgtcgtg gagatttttc
    37741 cggcttcaag agatgaacgt gccttacgtg tggagttttt tggagatgag gtcgaacgta
    37801 tccgagaagt caatgcactg acaggtgaag ttttaggaga aacggaacac gtagcaatct
    37861 tcccggcgac tcactttgtg acgaatgatg aacatatgga gcatgccgta gcgaatatca
    37921 aagcggaatt agaacagcgt ttaactgtct tgcgaaatga aaacaaactt ctggaagctc
    37981 aacgtttaga acagcgaacc aattacgata ttgaaatgat gttagaaatg ggctacacgt
    38041 cgggaattga aaattattct cggcatatgg acggacgtaa agaaggtgaa ccgccttata
    38101 cgctattgga tttctttcct gaagattttt tgatcgtggc ggacgaatcg cacgtaacca
    38161 tgcctcaaat cagaggaatg tataatggtg accgagcgag aaaacagatg ctagtagatt
    38221 acggtttccg tttgccatct gctttagaca atcggccact tcggttagaa gagtttgaaa
    38281 aacatgtcaa tcagatcatt tatgtctctg cgacgccagg accatatgaa catgaacaaa
    38341 cagataccgt tatccaacaa atcatccgtc cgacagggct gcttgaccca gtgatcgaag
    38401 ttcgtccaat catgggacaa atcgatgatc tagtaggcga aataaatgaa cgagtcgaaa
    38461 aagaccagcg ggtgtttgta acgacattga cgaaaaaaat ggcagaagac ctcacagatt
    38521 atttcaaaga attagggatc aaagtcaaat atttgcatag tgatatcaaa acgctggaac
    38581 gaacagaaat cattcgagat cttcgattag gtgaatttga tgtgttagtt ggaatcaatt
    38641 tgcttcgtga aggattagac gtacctgaag tttcccttgt tgctatcttg gatgcggata
    38701 aagaaggctt tttacgtagt gaacgttcct tagtccaaac gattggacga gctgctcgga
    38761 atgaagaagg taaagtaatc atgtacgcag acaaagtaac agattctatg cgtctagcga
    38821 tggatgaaac gtcaagacgt cgtacgattc agcagaagta caatgaagaa catgggatcg
    38881 ttccaaaaac gatcattaaa gaaatccgag atttgatttc tattacgaaa gaatcggaag
    38941 atgatacaaa agaagcggta caagtctcgt acgaagaaat gacgaaggaa gaaaaagaca
    39001 cgttattgat gaaattagaa aaagaaatga aagatgcggc aaaagctttg gattttgaaa
    39061 cagccgcgaa tgtgcgagat atgattttag aattaaaagc ttcaaagtag gaggacaaca
    39121 tggctaacga taaaattacg attcatggtg cacgtgccca taacttgaaa aatatagatg
    39181 taacgattcc acgagataaa ttcgtggtcg ttacaggttt gtccggttct ggaaaaagtt
    39241 ccctagcatt tgatacgctg tacgctgaag ggcagcggag atacgtagag agcctttctg
    39301 cttatgctcg tcagttttta ggacaaatgg ataagccgga cgtagatagc atcgacggat
    39361 tgagtccggc gatttctatt gatcagaaaa caacaagtaa aaatcctcgg tcgacagtag
    39421 gtactgtgac ggaaatcaat gactatttac gcttgttgtt tgcacgtgta ggacatccga
    39481 tttgtcccaa cgatcatatc gagattacca gtcaatcagt agatcaaatg gcagatcaag
    39541 taatggcttt gcctgagcgc acaaagatcc aagtgttggc accgatcgtg gtaaagaaaa
    39601 aaggacaaca taaaaaaata ttcgaacgaa tccaaaaaga gggatacgtc cgcgttcgag
    39661 tcgatggtga gatctatgat ttaagtgaag tgcctgagct ggagaaaaac aaaaaacatg
    39721 atatcgcgat cgtcatcgac cggatcattg tgaaagaagg gattcgttct cgcctatttg
    39781 attctttaga ggcggccctg cgattagcag acggctatgc tctggttgac gtgatcggtg
    39841 aagaagaaat gttgtttagc gaacactatg cctgtcctta ttgcggattt actgttggcg
    39901 aactagaacc aagactgttc tcattcaatg cgccttttgg agcttgtcca gactgtgatg
    39961 gtttaggtgt caaattagaa gtcgatcaag atttagtgat tccagataga acgaagacac
    40021 ttagtcaagg tgctatcgtt ccatggaatc caatcagctc tcagtattat cctcaaatgt
    40081 tagcgcaggc ttgtgaaagt ttcggtatcg atttagatac accattcgaa gaattaccgg
    40141 aagagcatca ggagatcatc ttgaatggga cagatgatct tttccatttc cattatgaaa
    40201 atgattttgg tggcgttcgc gatgtagaaa cgactttcga aggggtattg aagaatatcg
    40261 agcgtcgtta tcatgatacg aacagtgatt tcacgcgtga gcaaatgcgt ctttatatga
    40321 cagaattaac ttgtcagaca tgtaaaggtt atcgattgaa tccccaagct ctatctgttc
    40381 aaatcaatgg aacgaatatc gggcaaacaa atgagttgtc tattcaaaaa gcagtagatt
    40441 tcttctcaaa cttaacgtta tctgaacaag agaaagtaat tgccaaaccg attttaaaag
    40501 aagtaaatga cagactttca ttcttggaaa atgtgggact agactatcta actttgagtc
    40561 gcgcttccgg aacattatct gggggagaag cgcagcgaat cagattggct acacaaattg
    40621 gatcgaatct ttctggagtt ttgtatattt tagatgaacc atcgatcgga ttgcatcaac
    40681 gcgacaacga tcgactgatt ggctcattaa agaaaatgcg tgatcttggc aacaccctcg
    40741 ttgtagtcga acatgatgaa gatacgatgt gggcagcaga ttatttgatt gacgtcggac
    40801 ctggggccgg agaacaaggc ggacaaatcg tggctgcagg cactcctgaa gaagtagcta
    40861 atgatgaaaa ttctttgaca gggaaatatc tttcagggaa aaaatcaatc cctgtaccaa
    40921 aagaacgccg taaaggtaat gggaaagcaa tcaagatcac tggtgcttca gaaaacaatc
    40981 tgaaaaatat tagtgttgaa tttccattag gagaatttgt agcagtcaca ggtgtgtctg
    41041 gttctggaaa gagtacattg gtcaatagta tcttaaagaa atcgttagcg caaaaattaa
    41101 ataagaattc tgctaagcca ggtaaattca agacaatttc cggctacgaa agtatcgaaa
    41161 agatcatcga tatcgatcaa agcccaatcg gccggacgcc gagaagtaat ccagcgactt
    41221 atacaagtgt atttgatgat atccgtgggt tatttgctca aacgaacgag gcaaaaatgc
    41281 ggggttataa gaaagggcgt tttagtttca acgtaaaagg cggtcgttgt gaagcttgtc
    41341 gcggggatgg aattattaag atcgaaatgc actttttgcc tgatgtctat gttccttgtg
    41401 aagtatgtca tggtaaacga tataattctg aaacattaga agtgcattac aaaggaaaaa
    41461 gcattgctga tattttggaa atgacagtag aggatgctgt agaattcttc aagcacattc
    41521 caaagattca tcgcaaactg caaacgattg ttgatgttgg cttaggttat gtgacgatgg
    41581 ggcaaccagc aacgacattg tccggtggtg aggcacaacg gatgaaactt gccagtgaat
    41641 tgcacaaaat ctctaatgga aagaatttct atatactaga tgaaccaacg acaggacttc
    41701 atagcgatga catcgcccgc ttgttgcatg tattacaaag attagtagat gctggtaaca
    41761 cagttttagt gattgaacac aatctagatg taatcaaaac agcagattat atcattgatt
    41821 taggaccaga aggtggagaa ggtggaggaa cgatccttgc gactggaaca ccagaagaaa
    41881 tcattaacgt aaaagaaagt tatacaggtc actatttgaa aaaaataatg gtataaagag
    41941 gatagatagc tgagatagtt aaaaaaacat aaaaaaatga atttttgctt gttttattaa
    42001 tatcagtgtt ctagaatcat tacatggtag ttctttctac actgattggt atagataaaa
    42061 acttcctata agttcaatcc gttcaaaaaa gaattgagca atcggaggac tttcctttga
    42121 ttgctttttt ctttatggta tgatattcct tgtgtagttg gaaaagaaaa acaagagatt
    42181 atgagtaagt gagagataat gatgaacagt attgaaaatg aagaatttat ccctatatta
    42241 ttaggaagcg acatgaacgt ttatggtatg gcacgttctt ttaatgaagc atacggcaaa
    42301 atctgccaag catatgcttc ggatcagtta gcccctaccc gctacagtaa aattgtcaat
    42361 gtagaagtta ttccaggatt tgataaagac cctgtattta tcgagacgat gcttcgtttg
    42421 gcaaaagaaa gatattctga taagagtaaa aaatatcttt tgattgcttg tggtgatgga
    42481 tatgcagaat tgatctccca acataaacaa gagctgtcag aatattttat ctgtccatat
    42541 attgattatt ctttatttga aaggctgatc aataaagtaa gcttttatga agtttgtgaa
    42601 gaatatgatc ttccgtatcc taaaacattg atcgtcagag aagaaatgtt agtaaatgga
    42661 catttggaac aggaattgcc ttttgaattc ccagttgctt tgaaacctgc aaacagtgtg
    42721 gagtatcttt ctgtccaatt tgaaggaaga aaaaaagctt ttattttaga gactagagaa
    42781 gagttcgatt taattttagg ccggatatac gaagccggtt ataaaagtga aatgattgta
    42841 caagatttta tcccgggtga tgatagtaat atgcgtgtgc taaatgcgta tgtagatgaa
    42901 gatcatcaag ttcggatgat gtgccttggt catccactat tagaagatcc tacaccagca
    42961 tcgattggta attacgttgt gatcatgcca gattataacg aaaaaatcta tcaaaccatt
    43021 aaggcatttt tggaaaaaat cgaatataca ggctttgcca atttcgatat gaagtatgat
    43081 cctagagatg gagaatataa attatttgaa atcaatttga gacaaggtcg tagcagtttc
    43141 tttgtgacat tgaacggctt gaatctggct cgttttgtca cagaagatcg agtgttcaac
    43201 aaaccctttg ttgaaacgac ctatggaacg aatcaatcag ataaagcaag attatggatg
    43261 ggtgtgccca aaaaaatctt tttagaatat gctcgggaaa atgaagacaa aaaactagct
    43321 gagcaaatga tcaaagaaaa tcgttacggt actactgtat tttatgaaaa agaccgatca
    43381 atcaagcgct ggttgttgat gaaatatatg ttccataact atattccaag attcaaaaag
    43441 tattttcatg tgaaagaagg ctagttcatg gagaattttt tcagtatttt aggcggaatg
    43501 ggcacgatgg cgacagaaag ttttgttcgc ttgatcaacc accgaacgaa agctacaaaa
    43561 gatcaagaat atttgaatta tgtcttattc aatcatgcaa cagttcctga tcgtacagct
    43621 tatattttag atcgatcaga agaaaatcca atgccgtttc tgctggatga tattgagaaa
    43681 caaaatttat tgcgaccaaa cttcattgtg ttgacttgta acaccgcaca ctactttttt
    43741 gaagagttac aagcggcaac ggatattcct atcttgcata tgccaagaga agcagcaaat
    43801 gaacttgtcc gtcagcatac gacagggaga gtagcgattc taggaacaga aggaagtatg
    43861 aaagctggaa tctatgaacg cgaagtcaaa aatcttggtt tcgaaacagt gattcctgat
    43921 actgcgcttc aagaaaaaat caattacctg atctatcatg agatcaagga atcggattat
    43981 ttgaatcaag agctctatta cgaaatctta gaggaagcgg tagagcgcct aaactgtgaa
    44041 aaagtcatcc taggttgcac agaattatct ttgatgcatg aatttgctga agataatcat
    44101 tacccagtga tcgatgctca atctatttta gcggatcgaa cgatcgaacg tgcattagct
    44161 gaaagaagcg aggcattgga tacagcatcg gaaaagtaaa aaaattggat ttggggcaaa
    44221 tatcctaaaa gatatttggt ccaaatcttt ttgtaaaaga aaaagaaaac tggtaatgat
    44281 acgcccggga tgatataatt ttattatgca caatgtgaga ggggttcgta aatatgacag
    44341 ataatttgca attagtcatc ataacaggta tgagtggtgc agggaaaaca gtagctatcc
    44401 aaagttttga agatatgggc tatttttgta tcgataatat gccgcctcga ttgattccaa
    44461 aattctggga attgatcaaa gaatcaggta aagtcacaaa aatggcttta ggagtggatt
    44521 tgcgttctcg ttccttcttt gaagaaatcc aaaacatgct gatcgaaatc gaaaatacga
    44581 acttcatcga cacttctatc ttatttttag atgcttcaga cgaagaacta gtggctcgct
    44641 acaaagaaac aagacgagca catccaatgg cgatggacgg tttgatcact gaagggatac
    44701 gtaaagaacg ggcgatacta gacgacttga aagcccaagc ttccgtgatc attgatacga
    44761 caacattgac accacgacaa ttacgtgaaa aaatcaatga gtcattcaaa tcaaagggag
    44821 accaaggatt tcggatcgaa tttgtatcat ttggttttaa atacgggttg ccgatcgatt
    44881 cggatattgt gatggatgtg cgttttttgc ccaaccctca ttatatcccg gaactaagac
    44941 cattgaccgg aaaagatcag ccagtctatg attatgtgat gtcctttgat gaaacgcaat
    45001 cattctacca taaatttttg gatcttctgg aaactgtatt gcctggatac attaaagaag
    45061 gaaaaagcag cttgacagtt gcaatcggct gtacaggcgg tcaacaccgt tctgtggcat
    45121 tgactgaacg tttggcaaat gctttaggga aaaactataa agtcaatgtg acacatcggg
    45181 acaaggataa aaggaaagag acggtgaacc ggtcgtgaaa atgaaaacct accggataag
    45241 aaaaccaaag atcgtagtgg tcggcggtgg cactggtctg ccagttatcc tgaaaagttt
    45301 acgaaatcaa ggagcagata tcacagcagt agtgactgtt gcagatgatg gtggaagcag
    45361 cggtgcaatc agagaatcga tcgctatggc tcctcctggt gacttgagaa atgtcttagt
    45421 ggcgttatcg gatatgccac aattctatga agatattttc caataccgtt tcaaaaagga
    45481 agatcagttt ttagccaatc atacgatcgg taatctgatc attgccgcag tttccgagat
    45541 gcggggaagc acttatgagg cgattcaatt attagcaaaa atgatgcatg tagatggaca
    45601 tgtttatcct tcttcagaaa ctcctttgac cttgcatgct gtttttaaag acggaacgac
    45661 tgcagtagga gaatctaaaa tcgcgatcaa ccgtaaaacc attgaccgtg tgtatgtctg
    45721 caacacaaat gataaaagtg aagccaaagc ggctcgaaaa gtcgtttcag caattatgga
    45781 cgccgacatg gtcgttttgg gacccggaag tttattcacc agtatccttc caaatttagt
    45841 gataccagaa atcggcgaag caatgctcaa gacaactgct gaaaccgtct atatctgtaa
    45901 tatcatgacc caaaaagggg aaacggaaca tttcacagat gccgatcata tacgtgtttt
    45961 acacaagcat ttgaatcagc cttttatcga tacagtattg gtcaatacgg aaaaagtgcc
    46021 tgaagattat atggacccag agatctatga tgagtatcta gtacaagtcg cacacgactt
    46081 caacggattg agaaatgaag gatgtcgagt gatttccacc gactttttag aattgaaaga
    46141 tggtggtgtc ttccacgatg gagacaaagt agtagaagaa ttgttccgtt tagttttcgg
    46201 ttcaaaatat taagcaattt attgttggag aaaggaggag aataggatgt catttgctgc
    46261 agatgtgaag aaagaactaa ctggtttgga agttcatcga gaacatgcga aagcggaatt
    46321 agctgctttg ctgcgaatga acggctcttt aggtattgtg aaccagcagt ttattttgaa
    46381 cgtccaaaca gaaaatgctg caattgccag acgtatctat tctcttttga aagatcatta
    46441 tcaggtacga agtgagctac tcgttcgtaa aaaaatgaaa ttaaaaaaga acaatgtcta
    46501 tatcgtccgg ttgaagcaag gcacaaaaga tgtgttgatg gatcttgata tcatggatgg
    46561 tatgatgttc aatggacacg tttcggacga gattatggga aattcgcaaa aaatgcgttc
    46621 ttacttacgt ggtgctttta tggcctcagg ttcagtcaat aatccggaaa cgagtcgtta
    46681 tcatttggaa atattttcta tttatgaaca gcataaccaa gacatttgcg atatgttaaa
    46741 ttattacggt ctacatgctc gaacgcttga acggcgcaat ggctatattt cgtatttaaa
    46801 aggagcagaa aaaattgctg atttcttaac attgattggt gcaaccaact caatgctccg
    46861 atttgaagat gttcgaatcg tacgggatat gagaaattcg gtcaatcgtc tagtcaattg
    46921 tgagacagca aatctgaaca agacgattga tgcggcttct aaacaaatcg aaaacatcga
    46981 attgatcgaa gcaaaggtcg gtctacatgc ccttcctgaa aaacttcagg aaatcgcaga
    47041 acttcggctt caacatccag aggtcagctt gaaagaatta ggggaaatga ttccctcagg
    47101 tgcaatatca aaatcgggaa ttaatcaccg aattcgcaaa ataaatgaat ttgcggaaaa
    47161 actgcgtgaa gaagcagttt aatccaaaga aaaaactgat acatgaagca ggagatgcga
    47221 atgtatcagt tttttttaaa agctatactt gcttttcttc cgtcaaacta taattccaac
    47281 tttactggag taacataatg ttgaaaggct tctattgttt tttaatacaa tcgtataaaa
    47341 agcggggaga caactgaatg aagattttag ttttatacat aaacttttgc ttaatataga
    47401 agtcctgata tagataggat caagtattta tctataactg gagattaatt aaaaactgga
    47461 aggaactgct cgatcaacct tgagaactgt ttttcttact tctggtcaag attctcgtgg
    47521 ttggtggata aggatggttg ataagttcat tggattagct agtcgaaaac aaccaggtgt
    47581 aattaatgta gaagttttaa caaggggatg gagtgattta ttcagtgata atcataagtt
    47641 cataaatagt aattgggatg tatggttggt atacgttata cctgaacttg aactatcaag
    47701 atttggttta gaatttgaga atcgatgttt ataaagggag ggcaaaaaat gtgctttttt
    47761 acaactttta ctatcattat gattgcagta ctttttattt ttctagatat agcaaagcga
    47821 aatacagcat ttttattata tcgggtttta cttcgagcag gtctcataac atttatatcg
    47881 atcgttggat tttttctatt cacagttatt gtatttattt ggagaactac agcaccacca
    47941 ttgccagaga ttacatatgg agaatttccg tttagtcttg aatatgaaat agatgaggaa
    48001 agaattttga ttgaagatac ggtgattgca gaatttatag gaagttttag agggaatgtg
    48061 acaactcaac ctagacgaag ttggagtata aaacttttaa ataatagtgg agagttgaaa
    48121 gcatttcatt atgaattctt aataatagaa agtgaagatg taacaatcac tttaagtagt
    48181 ggctctgctg gatattttat gaatgatggt ggaagcaagc cacagctcac agtccgtgat
    48241 cgtattgcag gttttatgca tttttctcac tatgacttag aagaagctcg taaaatactt
    48301 gcagaatatg ggatcacatt aatcaattgg gaatatgcgc caccgataag aaattttttc
    48361 aatgattatt attagtctta taaaaaacag aatgtaaaat ttatgtgcgc gagtatttag
    48421 ttttccattt tttgtttgat agatatatag cattgttgaa gcatgggata gtggtgccaa
    48481 ttttatcaat gaggttggtc aggcagttaa cataattggt gatgctataa atccatttaa
    48541 ttggaattgg aggaattagg tgtggaaaca gtgagattat ggatattcat gaaaaatttt
    48601 cgttcggctt tgagatatgt tattctggaa tcaaaatcag gttattatct gattgacaca
    48661 gatcactata ctttttgggg aggctacctt tttccgattt ttaattggat aatcccccat
    48721 aaggttatga aaattaactt gcctgcagaa gaaataaata gattaatact caacaaagat
    48781 ttacaaagga aaagagagaa agaacattct aatgttgctt ggataggtcc agcatttgca
    48841 gtagtgactt cttcaattgt cggtcctatg ctagagagta tttatagtga tttttctatt
    48901 ggaatacgtt atttatttgt tactttaagt atagctgttc ttttgtgcat aaagggttat
    48961 gttagcaaga agaataaaga tattttaaca ctaatcggtg taaacaattt atctagtact
    49021 aaaattatac tgtttcctga atctataaaa gaaggatcaa ggttgttgat aatttttata
    49081 atgcttatac tgttttctgt tttatttggg gtgatgttta tag
//
LOCUS       DACGEU010000010        47186 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.010, whole genome shotgun sequence.
ACCESSION   DACGEU010000010 DACGEU010000000
VERSION     DACGEU010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 47186)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47186)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47186
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.010"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            150..1208
                     /locus_tag="IXR40_000551"
     CDS             150..1208
                     /locus_tag="IXR40_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014372913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HAQ4360424.1"
                     /translation="MNLFDIFRSTLTDMSIVSAITSTVFIILLGFVCRKKGIFSESVG
                     KILSKVVLTVALPALAFRAFMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYK
                     GDKQTTLRVLTIFGSTTFFGTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGL
                     KMEAKNIKAMFVNPIIIATFAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPW
                     LFQPMDYLAGLSSPLAWLAIGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILA
                     VLTATNILPVNFEALATIVIMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVL
                     TPVWIVVLQMIHGIGLFS"
     gene            1227..2246
                     /locus_tag="IXR40_000552"
     CDS             1227..2246
                     /locus_tag="IXR40_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate dehydrogenase"
                     /protein_id="HAQ4360425.1"
                     /translation="MRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIVSAKDH
                     DAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVPSYSPN
                     AIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRIGLTEA
                     VLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQMINEG
                     FLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSFKPWET
                     IPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNEVSLPK
                     ARQLR"
     gene            complement(2348..3064)
                     /locus_tag="IXR40_000553"
     CDS             complement(2348..3064)
                     /locus_tag="IXR40_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HAQ4360426.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(3033..3818)
                     /locus_tag="IXR40_000554"
     CDS             complement(3033..3818)
                     /locus_tag="IXR40_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAQ4360427.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            complement(3809..4558)
                     /locus_tag="IXR40_000555"
     CDS             complement(3809..4558)
                     /locus_tag="IXR40_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HAQ4360428.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            4856..5380
                     /locus_tag="IXR40_000556"
     CDS             4856..5380
                     /locus_tag="IXR40_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360429.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            5396..6895
                     /locus_tag="IXR40_000557"
     CDS             5396..6895
                     /locus_tag="IXR40_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HAQ4360430.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(6983..7585)
                     /locus_tag="IXR40_000558"
     CDS             complement(6983..7585)
                     /locus_tag="IXR40_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAQ4360431.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            7689..8645
                     /locus_tag="IXR40_000559"
     CDS             7689..8645
                     /locus_tag="IXR40_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HAQ4360432.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            complement(8950..9894)
                     /locus_tag="IXR40_000560"
     CDS             complement(8950..9894)
                     /locus_tag="IXR40_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAQ4360433.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSEPSRTSEKAENFAHRYN
                     IPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKKELAD
                     AMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDPKNRF
                     FNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNKENEL
                     AAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSEAMNY
                     EIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            10068..10628
                     /locus_tag="IXR40_000561"
     CDS             10068..10628
                     /locus_tag="IXR40_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360434.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            10621..11445
                     /locus_tag="IXR40_000562"
     CDS             10621..11445
                     /locus_tag="IXR40_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HAQ4360435.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            11455..12072
                     /locus_tag="IXR40_000563"
     CDS             11455..12072
                     /locus_tag="IXR40_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HAQ4360436.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            12090..12773
                     /locus_tag="IXR40_000564"
     CDS             12090..12773
                     /locus_tag="IXR40_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HAQ4360437.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            13456..14739
                     /locus_tag="IXR40_000565"
     CDS             13456..14739
                     /locus_tag="IXR40_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HAQ4360438.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            14755..15642
                     /locus_tag="IXR40_000566"
     CDS             14755..15642
                     /locus_tag="IXR40_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAQ4360439.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            15659..16495
                     /locus_tag="IXR40_000567"
     CDS             15659..16495
                     /locus_tag="IXR40_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAQ4360440.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            16498..17121
                     /locus_tag="IXR40_000568"
     CDS             16498..17121
                     /locus_tag="IXR40_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360441.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            17118..18410
                     /locus_tag="IXR40_000569"
     CDS             17118..18410
                     /locus_tag="IXR40_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAQ4360442.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     regulatory      18769..18866
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            18982..19563
                     /locus_tag="IXR40_000570"
     CDS             18982..19563
                     /locus_tag="IXR40_000570"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HAQ4360443.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     gene            19566..20873
                     /locus_tag="IXR40_000571"
     CDS             19566..20873
                     /locus_tag="IXR40_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HAQ4360444.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            21289..21777
                     /gene="purE"
                     /locus_tag="IXR40_000572"
     CDS             21289..21777
                     /gene="purE"
                     /locus_tag="IXR40_000572"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HAQ4360445.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            21761..22894
                     /gene="purK"
                     /locus_tag="IXR40_000573"
     CDS             21761..22894
                     /gene="purK"
                     /locus_tag="IXR40_000573"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HAQ4360446.1"
                     /translation="MINLVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVS
                     DCPAAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTD
                     LLAITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKG
                     QYVLKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHN
                     NILHETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRP
                     HNSGHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENK
                     PDWQFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            22907..24202
                     /gene="purB"
                     /locus_tag="IXR40_000574"
     CDS             22907..24202
                     /gene="purB"
                     /locus_tag="IXR40_000574"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HAQ4360447.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(24324..25712)
                     /gene="ltrA"
                     /locus_tag="IXR40_000575"
     CDS             complement(24324..25712)
                     /gene="ltrA"
                     /locus_tag="IXR40_000575"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HAQ4360448.1"
                     /translation="MRRPQKTRKLGYHQRASVEHEGYDEVRSTSCGEQRKQDGVENLF
                     GRILDRNNLNQAYLQVVRNKGAAGADGMTVDQLLPYLKEHREELLSNLRQGNYKPQPV
                     LRVEIPKPNGGVRKLGIPTVIDRMLQQAINQVLQPLFEPEFSDNSYGFRPNRSAHDAV
                     KKAKSYYEQGYRYVVDIDMKAYFDTVNHDKLMYFIERKVKDKQVLKLIRQYLMSGVME
                     NGLITTTEEGTPQGGNLSPLLSNIYLNEFDQVLENLGHKFVRYADDCNIYVRSKRAGQ
                     RVMKKSIQFLEEQLKLTVNREKSAVGSPLKRKFLGFCILPTKKGIKIRPHAKAKQRVK
                     SKLKQLTKRNRGRSIQLILKEIKQLMTGWINYYGIGEMKEFMRELNGWLKRRIRQYIW
                     KQWKNPRTKRKNLIRLGIDKAKAYEWSNTRKGIWSVSKSHILHRSLTDKELARQGYED
                     ISLKYQFVHSTY"
     gene            complement(26281..26658)
                     /locus_tag="IXR40_000576"
     CDS             complement(26281..26658)
                     /locus_tag="IXR40_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360449.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            26914..27642
                     /locus_tag="IXR40_000577"
     CDS             26914..27642
                     /locus_tag="IXR40_000577"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HAQ4360450.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            27642..27896
                     /gene="purS"
                     /locus_tag="IXR40_000578"
     CDS             27642..27896
                     /gene="purS"
                     /locus_tag="IXR40_000578"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010758866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HAQ4360451.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            27898..28569
                     /gene="purQ"
                     /locus_tag="IXR40_000579"
     CDS             27898..28569
                     /gene="purQ"
                     /locus_tag="IXR40_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HAQ4360452.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            28570..30792
                     /gene="purL"
                     /locus_tag="IXR40_000580"
     CDS             28570..30792
                     /gene="purL"
                     /locus_tag="IXR40_000580"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HAQ4360453.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            30777..32216
                     /locus_tag="IXR40_000581"
     CDS             30777..32216
                     /locus_tag="IXR40_000581"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010768528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HAQ4360454.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            32248..33291
                     /locus_tag="IXR40_000582"
     CDS             32248..33291
                     /locus_tag="IXR40_000582"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HAQ4360455.1"
                     /translation="MANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGFGGC
                     FDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEPLYF
                     LDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFAVGI
                     AEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKKTLG
                     EELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSWPIL
                     PIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVQESKVKEIVHEIEQAGEKVYEIGKVIA
                     KEKHRVVFIGEER"
     gene            33288..33866
                     /gene="purN"
                     /locus_tag="IXR40_000583"
     CDS             33288..33866
                     /gene="purN"
                     /locus_tag="IXR40_000583"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HAQ4360456.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            33863..35398
                     /gene="purH"
                     /locus_tag="IXR40_000584"
     CDS             33863..35398
                     /gene="purH"
                     /locus_tag="IXR40_000584"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HAQ4360457.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALAFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            35414..36688
                     /gene="purD"
                     /locus_tag="IXR40_000585"
     CDS             35414..36688
                     /gene="purD"
                     /locus_tag="IXR40_000585"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HAQ4360458.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            36810..37724
                     /locus_tag="IXR40_000586"
     CDS             36810..37724
                     /locus_tag="IXR40_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HAQ4360459.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(37857..39422)
                     /locus_tag="IXR40_000587"
     CDS             complement(37857..39422)
                     /locus_tag="IXR40_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HAQ4360460.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(39415..40866)
                     /locus_tag="IXR40_000588"
     CDS             complement(39415..40866)
                     /locus_tag="IXR40_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAQ4360461.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIREIKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(40880..41896)
                     /locus_tag="IXR40_000589"
     CDS             complement(40880..41896)
                     /locus_tag="IXR40_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAQ4360462.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            42116..43204
                     /locus_tag="IXR40_000590"
     CDS             42116..43204
                     /locus_tag="IXR40_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAQ4360463.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            43258..44784
                     /locus_tag="IXR40_000591"
     CDS             43258..44784
                     /locus_tag="IXR40_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HAQ4360464.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            44786..45991
                     /locus_tag="IXR40_000592"
     CDS             44786..45991
                     /locus_tag="IXR40_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAQ4360465.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            46248..>47186
                     /gene="guaC"
                     /locus_tag="IXR40_000593"
     CDS             46248..>47186
                     /gene="guaC"
                     /locus_tag="IXR40_000593"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HAQ4360466.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYV"
BASE COUNT        14781 a         8251 c        10362 g        13792 t
ORIGIN      
        1 aatcacttta cataagtttc aaaagtttct ttaatttcct attgttcaat aagtaacaat
       61 gtaaagataa aattaaaaat gttaatacgt attagcaaaa taaaagcttt ttttattgtg
      121 aataaatgaa cataattagg aggagaaaga tgaacttatt tgacattttt cgatcgactt
      181 tgacagatat gtcgattgtc agtgcaatca cttcaacagt ttttattata ttattagggt
      241 ttgtttgtag aaaaaagggg attttttctg aatctgttgg aaaaattcta tcgaaagtcg
      301 tcttaacagt ggctttgcca gcactggcat ttcgagcttt catgcaagat atcaatacag
      361 aattactgat gcaaggaatc aatgtcttga tttggggatt agttatttat attattctta
      421 ttctagtttc aaaacctttt ttcttaagct ataaagggga taagcaaaca acgttgcgtg
      481 tcctgacgat ctttggttct acgacctttt tcggaacgcc tatcgtcagt gcgatttatg
      541 gtcctgtcgg cgtgatgtat tcctcaattt tcaatattgg ctaccgaatc tttttgtatt
      601 cttatggata cataaaaatg agtggcttga agatggaagc taaaaatatc aaagcgatgt
      661 tcgtcaatcc aatcattatc gctacttttg ccggcctttt catttggctg ttccaagggt
      721 atctgccaca agtgtcagtt acaggtgcag aaggagagat aagccaagta gcgtttttgc
      781 gaattgacca gactgcaccg tggctatttc agccgatgga ttatttagct ggtttaagtt
      841 caccattggc gtggctagca atcggcgcaa cattaggtga agtaagcttc aaaaaagctg
      901 catctgaaaa aacttcatgg tattacagtc tagtcaaagt ggtatttgta cctgcattga
      961 atatcgtgat tctagcagtt ttgacggcaa cgaatattct accagtcaat tttgaagcac
     1021 tggcaacaat cgttatcatg atggctacac cagctgcaac agtggcagca gcctatgcta
     1081 tcagttttga tagggaggca cttttagcct ccaatgcatc cttactgtca actatttttg
     1141 ctgtggtact gacacctgta tggatcgttg tattacaaat gattcatggc ataggtttat
     1201 tttcataaga aatggaggaa gaaagtatga gaatcgcatg ttacggtgtt cgtccgaacg
     1261 agatagattt ttttgaaaaa ttgaatattt accattatga tctcagtctt tatgaagaac
     1321 tgttgacaca tgacaatatc gtgtcagcaa aggaccatga tgctgtattg ttgaggggaa
     1381 attgtatagc agatgagacc aatcttgcaa aaatgcagga atatgggatt cgttatgttt
     1441 ttacacggac tgtgggagtc aatcatatcg atctacaagc ggcagctgat tttggtatga
     1501 cagtagcccg tgtaccatcg tattcgccaa atgcgatagc agagttatct ttgacttttg
     1561 ccatgatgct tttgagaaat actgcgtata cgacgatccg aacatctttc aaagattttc
     1621 gagtggatga gcaaatgttt agtcgtgaaa tcagaaattg cacagtaggg atcataggaa
     1681 caggcaggat agggttgacg gaagctgttt tgtttaaggg actaggagcc aaagtgatcg
     1741 gctacgatat tcatcagaca gaagctgcta aaaaagtatt gacgttccac tcgcttgaag
     1801 agttattagc caaaagcgat attgtcagta ttcatgtacc tcatatccca ggtgaaaacg
     1861 atcaaatgat caatgaagga tttttagctc aaatgaaaaa aggtagcatc ttgattaata
     1921 cagcccgtgg agagcttcaa gataatgaag ctattttaag agctttgaaa agcaatcatt
     1981 tagctggttt tgcaaccgat gtttttgcaa atgaaacaga ggtttttttc cgatccttca
     2041 agccatggga gacgattcca gaccctgcta tccagcaatt agtagaaatg taccctagag
     2101 ttcttgtaac cccgcatgta ggttcaaata cagatgaggc attatcaaat atgatttcga
     2161 caagtttcga gaactttcgt gaaataatag aaactggaaa aacgaaaaat gaggtatctc
     2221 ttcctaaagc ccgtcaatta agataagaaa acatggatat tcgtcaataa aatgtttaaa
     2281 aatagtccaa gtaaacagtt gttacttctg tatacttgga ctattttgta tgggataatt
     2341 cgatgactca acagtaatct gtgagctttt tccgcccatt ctttgtcaat tcataacagg
     2401 ttagcggccg gccgatttcc aaatatttga ttctttcgtt caatatatct tgttctacta
     2461 aaaaattcaa atatttcttg acggatatac gtgacagtga gcttttttga gccagttctt
     2521 ttgttgaaaa aatagtatct tcttttagaa taaatgcact tatttttttt aaagtcagtt
     2581 ttgacagacc tttaggcaaa tcgatgaatg atggtatttc gtgaatggga gtggtgtggt
     2641 tgaatacttg atcgatcaat ttctgatcgg ctttttcagt cgtttggatt gtctgagaga
     2701 aagcaagata cttttcgatc gccagctgaa aacgttgcaa agtgaacggt ttgatcaaat
     2761 aatctaaggc accgtagcgg atcacattct ttatggtttc gatatcatct gcagcagtga
     2821 tcaaaatcac tgggatatca tttccttgct gtctaagcca agataaaaaa tggataccac
     2881 tttcgccagg catgtataca tcaagcagca gcagatctgc gtttttttgt ctgaaatatt
     2941 tttttccttc ttctacattt ctgaaacttt cgattacgtt catattaggg atgctttcca
     3001 caaaagtacg attcaattct gcaaccattg gatcatcttc gattatcagg acatttgtca
     3061 tcattttgat cttccttttt tggtaattct agatagacga ttgtaccgcc atttgtttgt
     3121 ttggaaaatt ctaaaaatcc accgtggcgt ttgacgattg aatggatgag attcaatcca
     3181 aacccacgat tgattccctt cgtcgaaaaa cctagcgtaa atattttttc tgagatttct
     3241 tctgatatcc cgacaccgtc atcgcagacg gtcacgatga atacttcagc ttctgtgtca
     3301 tagtttaaat gaatccggac ctgtccgttt ctttcatgtt tttgtagcac ggcttctttt
     3361 gcattatcaa gtaagttccc taacacttgc aaaagtgaat ggatggagtc atccatctcc
     3421 attttaggga taaaagaatc gctttctaac agcatttcaa cagattgttc tttggcttcg
     3481 tttattttgc ctaataaaaa accggcaatt gcaggtactt tgatcagact tgagacttgg
     3541 ccaatctctt ttttataatt ttgatttagc tgctggataa aatgggtgac ttcttcatac
     3601 ttcttcaaat caatcaaacc agaaatgaca tgaagtttat tcatgaattc atgggtttga
     3661 gctctcatgg agtttatata ttgtttcgtc cccccaagct cctccattaa tttcattact
     3721 tctgatcgat ttcgtaaagt tgcgactgct cctaaaaaac ggtcattgct aaaaagaggt
     3781 gtaacgctag aaatagtttc tatcccattt aaatacatgg attgagtccg aacggtcgtt
     3841 tgatgctcaa tcgtctcttt aaacaaaacg tcatatagat tatcactgat ttttttccta
     3901 cttcgaaatc caatagctgc tctgtttggt agaaaatgtt ttttgcaggt gtattgatca
     3961 agaggatagt tttatcagaa gagatggcta agattccttc atctacttca ttttcgataa
     4021 tcgttttttc acttaactgt tctgctattt cttgtggttc aagtccaagc agtacttttt
     4081 tcattttttg ggcaagaaaa acggcgccta tgatgcctac gctaagtcca ataatcaatg
     4141 aaaaaacaat cattttttgt ccatctttga cttgattgtc aatcgtgttg tttgttaagc
     4201 caacacaaac tgcaccaata atctcttgat cataataaat agggacgaaa tagcggaagc
     4261 cgaaccctaa cattccttct ttttcagaga aaaattcttg tcctccaatc acttttttca
     4321 catcttcatg acttgagaaa ggaagaccga tgtaacttgg gtctgcgtga gaatatcgaa
     4381 tgccttcagg gtccatgaca acgataaaat ctaaattcga tgcaatcatg atttcatttg
     4441 ttattccttg aatcgcatgt gtcgggtcac cagtctgcag ctttttttgg atgagtttat
     4501 cattggcaac gattttagca atgctagaga ttttatctga cacactagat cggttcatcg
     4561 aaagaataaa attcctgatc aatatggcag aaacaatcaa agaaacgaat gtggagaaac
     4621 aaacgacaag gatgatcgtg ttctggagct ttaatggttt tttcttaaaa aaaggaaaca
     4681 taggctacct cgaaagaatt tattgtgaaa attttaacat gaaaacaaaa atttaacaaa
     4741 ttgtcaacga taaacacaac cttcctataa aaaacaccac tgagtcggta aaagaagcta
     4801 tacagaattt tcaaacattg gtatgataga cgtagaaatg gaaggaggcg tgtatatgat
     4861 agggggaatc gcacttgaga cgatttattg gtatacattg ctgatttgtg caggattggc
     4921 agtcctattg attatttttg gagatgtatt cgattttgat ggcccgcttg atccgatgct
     4981 tattatccct tggttaactt tcacaagctt atttggtttt ctaggtgagc gtttaacaga
     5041 tcaatcatct ttatttttat ttattgctag tggaggcata tcgatagtgt tggtattttt
     5101 gcttaatttc tatatattga tgccgatgaa acatgccgaa tcaacgatgt cgtcttctga
     5161 aaaaactctg gaaggacaag tagctgttgt gatcacaccg atccctgtac gaggtatggg
     5221 agaaattcag ttgaaaagtg ttaccggttc cattagtcgt ccagcttgtt tttacagccc
     5281 ccaagaacag acagctgagc ggggaacgaa agtattgatc attgagatca aggaaagaat
     5341 ctgttatgtc atgccttatg aaagcatgat aaaagcttaa aggagcgtgt gttaaatgga
     5401 aataccagtt gtttttatcg cgatcgcaat cgcagctttg attttactga tgttgctgat
     5461 cgtctttgta gcgaagtacc agacagcaaa accggatgaa gcgttgatca tcagtggaag
     5521 ttatttagga agcaaaaatg tgcacattga tgaaagcaat aacaaaatca aaattgtgcg
     5581 tggaggtggc gcattcgtct tgccagtttt tcaacgttcg aatcggatca gtctattatc
     5641 gagtaaattg gacgtctcca cccctgaagt gtatacggaa caaggcgtac cggtgatgtg
     5701 tgatggtact tcgatcatca aaatcggttc atctgtagaa gagattgcta cagcagcaga
     5761 acagttttta ggcaagacaa gagaagaact ggaaaatgaa gcaagagaag tattagaagg
     5821 acacttgcgc tcgattcttg gttctatgac tgtagaagaa atctatcaaa atcgcgataa
     5881 gttcagtcaa agcgtacaag aagtcgcttc tgtagacctt gcaaaaatgg ggttgatcat
     5941 cgtttctttc actatcaaag aggtcagaga caaaaacggt tatcttgact ctttagggaa
     6001 accaagaatc gcccaagtca aaagagatgc agatatagca gaagcggaag ctctaaaaga
     6061 aacgcgtatc aaaaaagctc aagcagaaaa agaatcacaa gcagctgaat tacagcgaca
     6121 aacagagatc gcagaatcat taaaagaaaa agaactgaaa ttagcaacct acaaacaaga
     6181 acaagatgtt gctaaagcaa aagcagacca agcctacaat ttagaaagtg cccgagcaca
     6241 acaacaagta atcgaacagg aaatgcagat taaaatcgta gaacgtcaaa aacaaatcga
     6301 actggaagaa aaagaaatca cacgtcgtga aaagcaatat gattcggaag tgaagaaaaa
     6361 agcagatgcc gatcggtacg ctaaagaaca agaagcacaa gctcaaaaag tcaaagaagt
     6421 gactgaagcc gaagcagaac gattccgtgt ggaagcactg gcagaagcgg aagccaataa
     6481 gacacgttta gctggacaag cagaagccga agcagcacta gcaaaaggaa aagcagaagc
     6541 cgaagcaaaa caaaagatcg ccaatgcctt caaggaatat ggcgaagcag ctgtcttgag
     6601 tatggttatc gatatgctac cgcaattgat gcgcgaagca gcacagccgc taggaaatat
     6661 cgaaaaaatc tctgttgtcg atacaggaag cagttcagga gaaaccagtg gagcgaaccg
     6721 agtgacaaat tatgccacaa atttgctttc ttctactcaa gaaacactaa aagcgacaac
     6781 aggacttgac ttgaaggaaa tcgtagagaa tttgtcgaca cgtgggacta ctagccaagt
     6841 aaatatgtat gaagcgccaa aagaggcaga acaaaactcg atgaaggaag aataaagtag
     6901 tacacttcac cgttcaatca aaaatggagg aagacttttt aaagttcttc tctccatttt
     6961 tttattttat tgcaaaagaa aattagtcct cgctattttt cttttgtttt tggatcttag
     7021 cttctatctc ttgtaaattt gttcttagca atcgttcttt cttttggagt tcgaccaaat
     7081 cttctgatag ttcttccttc ttttctgttt caggaggacg aagaaagaaa ttgataccga
     7141 ttgcaatgaa tgtccctata aaagtatcta gtacacgttg gatagcatac aaagcggatt
     7201 cgccttgagg gatgctcaac gcaatcagca acaacgtagc tattgcggaa atgataccgg
     7261 aattattgtt aataccatct gacacgacga tcacaataat aactagaata ggaagcaaga
     7321 tcaattctac caaaaaatca ttgtgaaaat agcttttgac aaaaaaataa atgatagcta
     7381 atgtaccacc taatgtattg ccgatgatcc tagactttcc aaaagaaacg gttgtagtca
     7441 agtcctgacg caaagaaaaa acagcagata atgcagcaat catcgggatt cctcgttgag
     7501 tcaaatgaaa aaacaagata cataaaaaaa cagctaaggc acttttgatc gtacgcatac
     7561 ctagtcgaaa acggccaaat tgcatagaga ttctcctttt tggtcttttt actatcatac
     7621 ctaaactttt gtctgatagc tagtttttca ttattcaagt ataattaaaa taaaaaaggg
     7681 ggaagtaaat gcgtatagga atgcgaacag tcaaaacagt gatcagtgtc ttcttttcga
     7741 tggtcacagc gggtagctta tcgctgttgt attggccagc tgcagggatc attgcattat
     7801 taagtgtagg aaataccaag cgctctacat tgcgtacggg catgaatcga atcgcagcct
     7861 ttatattagc tacggcaaca gcactgttca gtttttttgc tgttgggtat actatttttg
     7921 gcttcagtct ttttttattc ctgttcatcc cgcttgcctc tcgcttcaaa ttaaccgaag
     7981 ggatagtagt aaattcggtt ttggtcactc attatttagt ggaggaaaac atgtcttggc
     8041 agctgatcgg caatgaagcg ggattaatgg cgattggatt agtatttgct ttgcttgcaa
     8101 atgtttacat gccagatcgt acgaagcagc tgaaggaaaa ccaaatacag atcgaaaaag
     8161 aatttcgaaa tattttgaga caaatggcag aatttctttt atcagaaaat aaagaagatg
     8221 tgcagatcaa atgcgaacat ttactgacat tcattcgcga aagccaagaa gatgccagag
     8281 aacatcaaga aaactactgg ctcagacagc cgctatacta cgaaacttac ttctctatga
     8341 gaagagcaca ggccaatgtg attaaagaca tgctggaaaa tctagagaga atccagcaac
     8401 cagcttatta tggaaaacat atctatggtt tattgattta tactgcagaa acattttcag
     8461 agtcaaatga tggcagacaa attttaacac gtattgaaga agtttatgta ttgtatcggc
     8521 aaatgcctct gccgactagt cgccctgaat tcgaggatcg agcagaattg ttccagtttt
     8581 tgcagtcttt taaaagtttt attgaaatca aggcagaatt ctcccaacaa aaaatccaaa
     8641 aatagaggtt gtgaattcag ctaatattca ggtcaaaaag ctgatttcac aacctcttct
     8701 ttaaacggtg ttctcctgtc aactcctcgg tcacaagtca caatattcaa caaacatgag
     8761 aagctgtttt ttgaaattgc tccttgtgac tcggagctga acggtaggct cacaacctct
     8821 ttcttaaacg gtgttcaaaa gctttcctct gcggtaataa gtccagccaa acgaaaaata
     8881 ggaggagcta tttttgtttg gctgttctta ttacttgatg cagaacagct ttttcacaac
     8941 cttttaaaat tacatatttt tccatagaac ttgcatttga tccaagattt cgatgacatc
     9001 ttttgtcaag aagagagagc gattgggcaa gtcaccttca atcatgtgta ccatattctt
     9061 tatttcgtaa ttcattgctt cagatgtatt cccgctttcg atgaattcct ttgtaccatc
     9121 tgtaaataag atctccgcac gatcagcacg cgggtaatca gcaatcgtca cataaccgtt
     9181 ctcaaaggca acgataccga cttttggcat ttttgcctga aaagtcaagc tgacagcagc
     9241 aagttcattt tctttgttac gcaagatagt gacggattgt tcgtccacgc ctgtttcaaa
     9301 aggaaccatt gtagaggcaa ctacttcagg ttgagagctc aaaaagaaac gagcgaaaga
     9361 tacagcatac gtaccgatat ccaacagagc tcctccagct aattctggat tgaagaaccg
     9421 gtttttaggg tctggttctt tgtaactgcc gaaaggtgct tggatcattt ttaaagcccc
     9481 cagttttcct gtatccatta ttgagcgtaa ctgctgataa agtggcatgt tgaagattgt
     9541 catcgcttct gctaagatca aattcttttc ttctgctaag cgcatagcgt cagccagttc
     9601 ttttttattc atcgtgatgg ctttttcaca tagaacgtgt ttgcctgctt ccaatgctgc
     9661 caagatatgg tcgatatgct gtctatttgg tacagcaatg tacacgatgt cgatttcagc
     9721 atcgtctaac atttcttgat agcttccgta agcttttgga atattgtaac ggtgagcgaa
     9781 gttttccgct ttttctgaag ttctggaagg ttcgctcgtc tcttgattga agctttcggc
     9841 aaactcatgt gcgatggtac caagaccaac gattccccat tgatattttt tcatctgaaa
     9901 acgctccttc atagttggat tgagtttctt gtctgtctat tattataaca aaaatcacga
     9961 agaataaaga ggagaggact tgaaacatta aaaaaaatga aagcagcgat ttaagaggtg
    10021 ctttttgatc aaaacttaag tagaatagtt aaaaggaggg gataaacgtg catcaagtat
    10081 atattgatct tattatgagt gtattattag aacagtttga aactgaaaaa aattttttag
    10141 atgaatactt gctgatcagt ccagaacaat ggcaaaaatg gaaagatggc gagaaaaatc
    10201 tgccatctga agcgatgcag aaagtaaaaa atcttttcac tgattatgaa tggatgctaa
    10261 cgcaaaagat tttgcgtcaa acgattattt ttcccgaaaa acgaaacgtt gccgttgcag
    10321 agtacaagca aatcaaaaca cgcatcgcgc aaaaatggct tagcagcaaa gcagcaaaag
    10381 tcgagctgat ccctttgaaa aataatcagc aggctggtag ataccttgac ttgaaagtaa
    10441 gtattcaata tgatgaatgg ggctatgatg atattttgaa ttttcgtctg ccagcagatg
    10501 ttcaaaaaca gatcgaagga gaaaaaatcg aacttctcga ttgggtgaat gaaaatctgg
    10561 aagaaactta cgttcatgag gcgaatgggg aacgtgaaga acaacgaaag gatttttcaa
    10621 gtgaataaat ttttaggatt tggagcagtt gtgattatga tcgcagcaat gggctatgtt
    10681 atttttagcg atgatgattc gcatgttcaa gccggcaatc aagcagtcga acgaacaagc
    10741 accaaaacaa ctgctagtaa agaaaagaac agtcaaacaa ccagcagcaa ggtaaaggac
    10801 aaagaaacaa aagatcgtac gtccaaacaa ttgccagatg ttaaaacaga cgattggaag
    10861 ctagttttgg ttggtccaga tcacaaatta gaaaaagaaa ttgatgagtc tactcaattg
    10921 gcatcattaa gtaacggata cttgatcgac aaacgcattg ctccagaata tgaagcattt
    10981 gccaaggctg ctgaagcagc tggatttcca ttagtgatgg tctcagctta ccggtctgta
    11041 tcatcccaac aacaagtttt cgaacaaaat gtccaagatg tgatgagtcg tcaaggtgta
    11101 tcagaagagg aggcgacaaa gattactaaa gaaacgatta cggagccagg atacagcgaa
    11161 caccacacag gtctggcagt cgatgtcgtc gatcaaaact ggtacaacag ttatccttct
    11221 actgtattgg atgcaagtta cggagatcag cctggagcta aatggatcgc agataatgct
    11281 gcgcagtatg gatttatcgt tcgttatcca aaaggacacg aagatataac taagatcaca
    11341 tatgaacctt ggcacttacg ttatgtcggt aaagaaaacg ctgagtatat caccaaacac
    11401 caattgacgc tagaagaata tctgaatgaa ttaaatgaaa agtaggaatt gatcatggcg
    11461 aaaaaaaagt ggaaaaagca aaagcgcaag aatatccgtt ggccagcagt ggttgccggt
    11521 gtagcagtga tactcttagc ctttgttttt tccttgaaga atctgtcttc tccttttact
    11581 gataatcagc aagaaaatga agcgcaatcc catcagcaat ttattgaacg gcttgttccg
    11641 catgcccaag aactacaaga tggttatgga gtgcttccta gtatcatttt aggacaagct
    11701 atattagaat caaattgggg aaaaagtacc ttggctagca aatacaataa tcttttcggg
    11761 atcaaggctt atggggatca gaagaaagta agcctggaaa caaaggaatt tgttaacgaa
    11821 gaatggataa ctatccaagg agacttcaaa gtgtatgatt catgggaaca gtccatggat
    11881 gaccatacac aactgttcgt ccaaggagta gattggaatc ctgcgctgta tgaaaaagtg
    11941 attacggcca ccaactatca ggaagccgca caagcattgc aagatgcagg ttatgcgaca
    12001 gaccccggtt atgcgcaaaa aatcatccag gtcatcgaga cgtatcaatt gaatcagtat
    12061 gaccggagat agcaaaggag aagtggctga tggcagaaca atttacgcca gaaatcatga
    12121 cggaattgag aaaagatatc gtaagagtac cggaaatcat tttagaagca agcgggatca
    12181 agatatttgg aaaattgatc cgttcgatca tctttactac ggatattgcg atcatacgta
    12241 atacaaatgc gaatgcagta attgctgtgt atccttttac acctcatcca gcgattacta
    12301 aaagcattat tgaggcagct gacattccag ttttctccgg tgtaggtggt ggtttgacac
    12361 aaggtgctcg ttcttcctac atgagcatgt tcgcagaagc gcaaggttcg ttaggggtcg
    12421 ttttgaacgg tcctacgcct ttagagacag taaaagaagt ttgtcgagta gttgatattc
    12481 cagttatcag tacggtaacg tcgaaatata cagaaataga tgaaaagtta gcagctggta
    12541 tttcgattat caatatcagt gcaggtaaag aaactgcaga agcagtacgc cattttcgta
    12601 aaaaatatcc tgaacttcct atcattgcga caggtggtcc aacggaagaa agtattgctg
    12661 agaccattca agcaggagca aatgccatca catatacgcc accaagtagc ggagagcttt
    12721 ttagtcgtaa aatggaaaaa tatcgggaaa ctgagaaaaa gaatcatgaa taacaggtga
    12781 gaatcaaaag acgaggaaga gcagatagtg gctcttcctc gtcttttgta ctccagtact
    12841 atttgttcag aattcaaaaa aaagagaaat ttttttgttt ttttacctgt aatgtacata
    12901 agaagagtta aaaccttttg ttattattag cattctaaca aaaaaatgtc ttgatttatt
    12961 gaagcgcttt ctatagaatg aaaaacgaat aaaaactaaa aaaggcaccc gacaatttag
    13021 tagcagctaa attgtcgggg cttgaaaagt cagcgggaac tgaccaatca agttgccata
    13081 gtcaatgctt gtgcatcgac gtgtatattg tacctaattt catacagaat tactagttat
    13141 ttttctgttt tttagggaag agcgcacacg aagaagcatg cttatttagc tatgtcaagg
    13201 atattgggca gttgtctgat atcctttttt ctttgcgtaa ttatcctccc atcattgaag
    13261 caagaagtgt ttttagcgat gaaagaagaa tcagcactat ctaatttttc ttgaaagtat
    13321 tgagttgttc atcctaggca gaacgataag gcaagtcttg gtttttattc cccttgaaaa
    13381 agatcgttta ataaatatgt tctgtataaa aatacagtat attgaaaaat aacaatggaa
    13441 gtagaggtgc agagaatgaa gaaaagaatg agaatcatct tagctttaag tgttatgtta
    13501 ttcttcttga cggcttgtgg gcaagaagat gacaaaaaaa tcacgctgaa catggcttgg
    13561 tggggttcgc aagtccgaca cgatgcaaca gtaaaagtaa tcgagcttta tgaagaaaaa
    13621 aatccccatg tgacgatcga ttatgaattt tatgattatg aaggatatta cacaaaatta
    13681 ggtacactag cagcatcaga tgatatctgg gacattttcc aactgaacaa tcaatttcct
    13741 caatacatca atcagattga accattagat gaatatgtgg agcaagggat aattgatatt
    13801 tctaatgcag atgaatccta tttagcaacg acgacttacg acgggcaatt agttggactg
    13861 tctaacgggg tgaattcgtt tgcgattgct tacaataaaa atatatttga acaattaaat
    13921 atccctgaac cagcttcaaa ttggacatgg gatgaatttg aacaaatcag ctatcaaatc
    13981 actgaagaat taggaatcta tgctatttca agattcgaag attttatagc tggctgtatt
    14041 attcaaatac cacaagttga gaaaggattg aatttttata atcgggaaga tctatctaac
    14101 agcttgggat ttgaaaatcc agactatcta acagattttt tccagctgcg taaaaatctg
    14161 gtagacaaag gggcccatcc agaaccaggt ggtggagctg caagtacgac ggatctgtct
    14221 tttcaggcgg ttagggatag agaagcggca atggtgtttc tatcaagtaa ccagttgaca
    14281 gaaatattgt caggggctcc tgaagatatg gagattcagt tgattaatcc acctcgcaga
    14341 aaagcagatg gagaatctgg tatcccttta cgttcttcgc aaatgctgag tatggcaaaa
    14401 agctcagccc ataaagaaga agctgctaag tttattgatt tctttcaaaa cagtgaagaa
    14461 gccaatgaaa ttttaaaagg agaacgtggt gtaccaatca tgtcgaatat tcgagaacag
    14521 ctcgctcgtg cagatgatgc aactttgcaa gcgacatttg attatttaga aatgatttcc
    14581 gatatggaca acggcgaagt gaatgtcttt gatagtgctt tgaatccgga aattcaagac
    14641 caatacaatc ttttagttga aaaagtcatt tatgaagaag taacagcaga agaagcagca
    14701 gagagtcttt atgagtttgc gtcaaacatt ctaggatagc agcaggagga aggcatgaaa
    14761 aaagaaaaac taaaacggtt cttggatcaa gacaatgtgg tcggttacgt atttgcttct
    14821 ccattcatcc taggatttct attgataaca gtgataccga tgatcttgtc actttattat
    14881 tcgttcaccg attatcgttt gggaaatcca gtctcatgga tcggcttgga taattatata
    14941 aagatgctga gtgatgcccg ttttttgaac tccatccgag tcacttttct ctatgtattt
    15001 gcatctgtac ctgtgaaact gatctttggt ctattgattg cttatctttt aacgaggaat
    15061 atcaaaggaa cgactttctt tcgttctttg tattatgtgc ctagtttgat cggtggcagt
    15121 atttctatcg ctctagtttg gcgggagttg ttttctaaaa acgggttagt gaatattttc
    15181 ctggaacgat taggcgcacc tgcgctttcc tggtttagcg atcaaaaact ggtcatgatc
    15241 cctcttgttt tgatgtctgc ttggcaattc ggttcggcaa tgatcatctt tgctgcaggt
    15301 atcaaagaga tcccaggctc gtattatgaa gcggcagaga tcgatggagc gaacaaatgg
    15361 cagacgtttt acaagatcac gttacctctt ctttcgccga tcattttgta taacttggtt
    15421 atgcagacaa tcgcggcgtt tatgactttt acgcaggcat ttatcattac ccaaggtggt
    15481 ccgaatgatg ccacgaactt ttatgctctt tatgtgtata accaagcttt ttcttttaat
    15541 tctatggggt atgctagtgc tatttcgtgg atcatgctgt tgattatggg agctgtcacc
    15601 tttctgattt tcaaatcatc aaaaaaatgg gtcgttgtgt gaatgagagg aggaagaaat
    15661 gaataataca gtaacgaaat ggtttcaata cggttttatt ttgctattag gtctagtcat
    15721 gatttatccg gtcttatgga tgatcgcagg ttcttttaaa acggatcaag agattatgag
    15781 tggttcgctg aatttgattc cagagacttt tcaatgggaa aattacgcaa aaggatgggc
    15841 ggggtttgct ggaatttcat tttttacttt ctttaggaat tcgtttgtca tctctgcagt
    15901 ttcgacgata gggacagttc tgagctcgac ttgtattgct tacgcattat cgagaatcga
    15961 tttcaaagga aaaagattct ggttcgtcgt catgttagta acgatgatga ttcctgcaca
    16021 agtgattttg attccgcagt ttattattta caatcggctg aatttggttg ggacgtatgt
    16081 gccgctgatt ttaccacatt tttttggaca agcatttttc atttaccaga tcatgcaatt
    16141 catggtcagc atccccaaag agttagatga atcagcgatt attgacggat gcagcaagta
    16201 tagtgtcttt accaaaatta tttttccttt gctgaaacct tcgatcatca cgacgatcat
    16261 catccagttt tattggaaat gggacgactt catgggacca ttgatttatt taaacaagcc
    16321 gagatcttac acggtatcga ttgccatcaa attatttgca gacgctggat ctagtacgac
    16381 ttacgcgagt atgtttgcga tgtctacgtt gtcgctgcta ccggtttttc tgattttctt
    16441 attcttcaat aaatatcttg tccaggggat cagtacaagc ggtctgaagg gctgaatatg
    16501 aaaaagccaa tagaagagat gtttctttac aagctcaact actatgtctg tcggattttt
    16561 ttaaccagtc ttatcagtaa tgctcttttc gctttagttc taggatgttt gttcacttta
    16621 ggattagtgc tgtctgctcg tgttgtctat ctgatttatt ttttgatgat gtatccttct
    16681 tattatctat ctgtccatta cttggcagaa aaaaaggtat gttggaggaa aggaaaaatc
    16741 aaacggatgt gtttcatcat tacgttgttt cagctgtttg tcattatttt tgcagttgat
    16801 tggtatttat tagtgggaaa gattggagct tggtatctga ttccttttct attgtgtctg
    16861 ttgctttttg tatcccatag tttttttagt acgctaattg atatctgcaa agaagataaa
    16921 gcagatagtc ttgtttattt gatcaaaagg aatatctggc tgttgtcaaa aaacgtcaag
    16981 gggtttctgt ggtatttatg ccttttgtat ggactgttct ggtgtataca gcatgatttt
    17041 ttactcactg cattactgta tccagggctg ccatttgtca cagtattttg cttaaaagaa
    17101 aaggagaatg actttaaatg aagaaaaaat atgtacaagt cggacttggt gggagagcgc
    17161 gtttttttta tgaggcaatt gcctctacgt atcatcaaac ttgtgaacta gtcggttttt
    17221 gtgatgtatc tcaaacaagg atggattatg caaatcggat acttgtgaac aagtatggac
    17281 agaaaaaagt aaagacatgt atgccatcac aatttgagca actactggat gacgtacggc
    17341 cggctgaagt cattattacg tcagtagatc gaacgcatca tgattatatc attcgtgcaa
    17401 tgaaaaaagg atatgatgtt atttgcgaaa aacctctgac tatcgatgag gaaaaagctc
    17461 aagaaataat aacggtccaa aaacagacgg gaagaagcct gcgagtcact tttaattatc
    17521 gttatgcacc gtatcacacg aagataaagg aactgataga aagtgatgtg attggtgatg
    17581 tgttttctat ccacttcgaa tggctgttaa atacgcaaca cggggcagat tatttcagaa
    17641 gatggcatcg aaataagcac aatagcggcg ggcttcttgt tcataaatct acccatcatt
    17701 ttgatctagt gaatttttgg ttgaacagcc gtccccaaaa ggtatttgca ttcggtggat
    17761 taaactttta tgggatgcat aatgcggaga aacgcggagt agaaatattt tacagtcgat
    17821 gctatggaag cgaactagct aaagctgatc catttgctat agacctgtca gccaatgagg
    17881 aattgcgaga aatgtattta gaagcagaaa aagacagtgg atatattcgt gaccgcagtg
    17941 tattttccga tgatatctct attgaagata cactaggcgt aacggtcaaa tatgaaactg
    18001 gtgcgatttt gacgtattcg ctaaacgcgt atatgccgtg ggaaggattc aatgtttctt
    18061 tcaatggcag caaaggacgg atcgaaatga aagtgatcga aaagtcttac atcaatgcag
    18121 gtggagataa aaaggatgaa ggagcagccg ttcttcagtc catccatgtc tatccgatgt
    18181 tcggtgagcc atatgaggta atcgtcgaac aagaagcggg cggacatggc ggaggagatc
    18241 cgcgtttatt agatgatcta tttggtgaag aaaaagaaga agatccgtgg aatcgggcag
    18301 caactcacgt agatggtatt ttgtcgattt tgacaggaat cgcagcaaat cattctattg
    18361 cttcaggaaa agcagtagtg attgacgagc ttgtcagctt aaaagaataa gaatagattt
    18421 acggaaatta cttcccgtag tttataaaat cttgccttat tgccgatagg ctgtcttttg
    18481 aacactattt attcggaaaa aggggctatg acatgctttt tgtcatgcct tctttttatg
    18541 tgggctgctt ttttagatag gagaaaataa aaataactat ttaaacccga acaaaaagga
    18601 ataatgcatt aaaaatcatt agattttaca aaaaaataag taaaccacgt tgtcagtttc
    18661 agaaagtagt gttagactgt tttcaatatt tgaaacaaca ttttttattc aaatatggca
    18721 aactgccttc acgtgcaaaa cagttgcaag aaaatgaatt tacactatta ttagttttac
    18781 atacctactt atatatcgtc ataatatgga tgacagtttc tagccagtac cgtaaatgct
    18841 ggactataag taaaagattg gctatttcac ccttcttttc ttatgataaa gtggagggtg
    18901 tttttcttta acagaaacat agtaggtttt tgcacaaaag cggttatttc ggtattaata
    18961 aatgataaag gagcaaataa agtgaaagaa ttagttgaac gtattcaaaa agacggacgt
    19021 atattaggcg agggcgtatt aaaagtcgac agcttcgtca ctcaccaagt agaccctgta
    19081 ttgatggaac aaatgggaaa acggtttgca gaagtattta aagaacaagg aatcacgaaa
    19141 gttgtgacca ttgaagcttc tgggatcgca ccagctttat ttgctgcaag agaattagat
    19201 gttccaatga tcttcgctag aaaagcaaaa agtttgacga tggatgaaga attattgaca
    19261 gcttctgttt attcttttac gaaacaagtg acaagtacga tttctatttc tcgtaaattt
    19321 ttatcttcag aagacaaagt attgattatc gacgatttct tggcaaacgg acaagcggca
    19381 aaaggattga tcgaattatg ccagcaagct ggagcgcaag tagaaggaat cgggatcgtc
    19441 atcgaaaagt ctttccaaga tggacgtcag ttacttgaag aaatgggatt gagagtcgtt
    19501 tctcttgcgc gtattgcttc cttgacgaat ggacaagttg agtttcttga ggaggacgca
    19561 taatcgtgga aaaagaaaca caaaatggaa aagctgcggt tttagggctg cagcatctgc
    19621 tagcgatgta tgcaggagca gtagcggtgc ctcttttgat cggtacagga ctaggcttta
    19681 atcaagaaca gatgacttat ttgatttcaa ttgatatctt tatgtgtgga ttagcgacat
    19741 tattgcaatt gacagttaac cgatttttcg gaattggctt gcctgtcgtt ttaggatgtg
    19801 cgatccaagc agtagctcca ctgatcttga tcggaaccaa tgaaggagta ggagctatct
    19861 acggatctat tatcgcttct gggatctttg ttgtgttagt ttctggtgtc ttttctaaaa
    19921 ttaaaaaact attccctcct atagtaacag gaacggttat caccgttatt ggtttgactt
    19981 tgattcctgt agcaatcgag aaaatgggtg gaggtaatgc aacagcagct gattttggtg
    20041 acaaaacaaa tctgctactt gcatttgtga cgattctcct aattgtaggc gtgcaaatgc
    20101 tggcaaaagg gttcattcgt tcaatcgcgg tattgattgg tttagtcgga ggaagcatct
    20161 tagctgcttt catgggaatg attgatctga gcgcgattgg agatgcgccg ttgttccatg
    20221 ttccacaacc cttttatttt ggtaaaccaa ctttcgacgt atggtcgatt ttactaatga
    20281 tcatcatttc catggtcagc atggtagaat caacaggtgt atattttgca cttggtgaca
    20341 ttactgggaa aaatgttgga gaagaagaat tgaaaaaggg atatcgtgca gaaggacttg
    20401 ccgttatctt aggcggtatt ttcaatacat tcccttatac tggcttttct caaaatgtcg
    20461 gattggttca actttcggga atcaaaacaa gaaaacccat ctatttctct gcattcttct
    20521 tgattgtttt aggattattc cctaaaatcg gtgcgttagc acaaatcatc cctgagccgg
    20581 tacttggtgg aggaatgtta gtcatgttcg ggatggtggc agtccaagga atccgtatgc
    20641 tgttggaagt tgatttcagc aatgataaaa atctattgat tgttgctgtt tctgttggat
    20701 ttgggctggg tttcaatgtt acgccgacat tattcagtca aatgccgcaa acattgcaaa
    20761 tgttcactgg aaatggcatc gtaatgagta gcattacggc tatcatattg aatttgatct
    20821 ttaatggatt gaaaaaagat gaagaaatat tggaagaagc cttcaagaag taatagagca
    20881 aaagaaaggt tgtgaaatca gcgttttgac ctgattgtta gagaaacaaa cggaaaaata
    20941 gttcctcgta ttttgccgtt tgtttgagct aataccgagg gtcagctgat tgaacaccgt
    21001 tgaaggaaga ggtcgtgagc ctgccgttca tctccgagtc acaaggaaca atttcaaaaa
    21061 aaagcttctc atgtttgttg aatattgttc cttgtgaccg aggagttggc aggagaacac
    21121 cgtttatcca taaaaaggaa tgtgacctaa cttttgtcac attccttttt tttatcttta
    21181 ataaacacga acaataaaat gtttttcttt gttaacattc gaaatttctt tgacatcaaa
    21241 aaaagtgatt gttaaaatat gaatgtagaa aaactgggag gaaaaacaat gacagcaaaa
    21301 atctctgtga ttatggggag tacttcagat tgggaaacaa tgaaagaagc atgtcaaata
    21361 ttggatgaat tcggtgtgtc ttatgaaaaa aaggtcgttt ctgctcatcg aaccccagat
    21421 ttgatgtttg aatatgcaca aaacgctcga aaaaaaggaa tcaaaatcat tattgcagga
    21481 gcagggggag ccgcgcatct gccgggtatg gtcgcatcaa aaacaacttt gccggttatc
    21541 ggtgtaccgg tccaatcacg aacattaaat ggtttggatt cgcttctttc gattgtccaa
    21601 atgcctggag gagtacctgt agctactaca gcaatcggaa aagcgggagc aattaatgct
    21661 ggactacttg cgatacagat gctttccatg tatgatttag aattggaggc taaattggct
    21721 gaaagacgtt caatgttggc taaaactgtt atagaaagta gtgatcaact tggttaaacc
    21781 tttgttgcct ggttcaacga tcgggatcgt cggtggcggt caattaggtc gtatgatggc
    21841 gattagtgca aaagaaatgg gctttaaagt aggtgtgctg gatcctgtga gcgattgtcc
    21901 agccgcacaa gttgcagatt ggcacattga aagtgtctat gatgacacct ttgcgctgaa
    21961 agagcttgcc agaagaacag atgtcattac ctatgaattc gaaaacgtca gtgtagaggc
    22021 gttaaatgcg attttaccca tgtcatttat tcctcaaggg acagacttgc ttgcgattac
    22081 gcaagaccgc ctgttagaaa aatctttttt ggaaacgaat aacatcgtga ttgctcctta
    22141 tgcaacgatc gtcagtccga cggatatcca agatgcgatt gacgggatcg gctatccttg
    22201 tgttttgaaa accactcgag gcggctatga tggcaagggg cagtatgttt tgaaaagtcg
    22261 ggcggatcta gctcctgcca tggacctttt aagagaagga acctgtgttt tagaagcatg
    22321 gatcccgttt gaaaaagaga tttcgatcat ggtggcagga aatggtcaag gagatttcac
    22381 gacttttccg gtcgtggaaa acatccacca caacaatatt cttcatgaaa cgattgctcc
    22441 agccgcgatt gatcaggatg tgatcgagga ggctgagcgt attgcccgtg tgattgcaga
    22501 agcagtgagc ctttcaggtg ttttaggggt agaaatgttt ttaacaaaaa caggcgggct
    22561 atatgtgaat gaattagctc ctcgtcctca caattctgga cattattcta ttgaagcttg
    22621 ttctatgagt cagttcgatg cccatattcg aggtatttgt ggttggccat taggagaaaa
    22681 agtacgtttg ataagcaatg cagtaatggt caatgttttg ggagaacaac tgctggaaag
    22741 ctatcgcttg attgagaata agccagactg gcaattccat ttctatggaa aaaaacaagc
    22801 aaaaaaaggt cgcaagatgg gacatatcac tatcttgaca gaagacatcc agcaaacgct
    22861 ggaagaaatc aaacaaacga atatttggga ttagaggaga aaaaacatgt tagaacgtta
    22921 tacacgccct gaaatgggga atatctggac ggaagagaac aaataccgtg cgtggctcga
    22981 agtcgagatt ttagcagatg aagcttgggc agaacttggt gaaatcccgc aagaagatgt
    23041 gaaaaaaatt cgtgagcatg catcatttga tatcgatcgg atcttggaaa tcgaaaaatt
    23101 aacacgccat gatgtcgttg cgtttacacg agcggtttct gaaacattgg gagaagaaag
    23161 aaaatgggtc cattatggtc taacaagtac ggatgtcgta gatactgctt atggctatct
    23221 catcaagcaa gcaaatgata ttttacggga agacttgaaa cgttttacgg aaatcattgg
    23281 cgaaaaagca aaagaacaca aatatacagt gatgatgggt cggacacacg gtgtccatgc
    23341 tgaaccaact acttttggat tgaaacttgc cacatggtat tcagaaatga aacggaacat
    23401 cgaacgattt gaacatgcgg caaaaggagt agaagcagga aaaatctcag gagcagtggg
    23461 aacgttcgca aatatcccgc catttattga agagtatgta tgtaaacaat tggggatccg
    23521 tccacaagaa atctctactc aagttctccc tcgggatcta catgctgaat atttctcagc
    23581 gatggcgctt attgctacaa gtattgaacg ttttgcaaca gagatacgcg gattgcaaaa
    23641 atccgaaaca cgtgaagtag aagaattttt tgcgaaaggt caaaaaggtt cttctgctat
    23701 gccgcacaaa aggaatccga tcggttcaga aaatatggct ggtctagcca gagtggtgcg
    23761 cggacacatg gtcactgcct atgaaaatgt cacattatgg catgaaagag atatttctca
    23821 ttcttcagca gaacgaatca tcttgcctga taccacgatt ttattgaatt acatgttaaa
    23881 tcgttttggc aatatcgtta aaaatctaac ggtctttcct gaaaacatga agcggaatat
    23941 gtctgcaaca tttggtttga tttatagcca gcgcgttatg ctgaaattga tcgataaggg
    24001 aatgacaaga gaagaagctt atgatcttgt tcagccaaaa actgcgtacg cttgggacaa
    24061 ccaagtgcag ttccgcccgc tgttagaaga agatccaacc atcacatcgg tattatctaa
    24121 agaagaaata gacgatgcct ttgattatca tcatcatttg aaaaacgttg acgtgatatt
    24181 caaacgagta ggtttggaat aaagaagagt gagttgcaaa attcaattaa aatagaatag
    24241 caaaaataat cgagtagagg ggaaagccaa ctgaccttcc gcccctctca caccaccgta
    24301 cgtacggacc cgtatacggc ggttcaataa gttgagtgta cgaactggta cttcaaggag
    24361 atgtcctcat atccttggcg ggccagttct ttgtctgtta atgatcgatg aagaatatga
    24421 cttttggaga ctgaccaaat accttttctt gtatttgacc attcatacgc tttcgcttta
    24481 tcgatcccta aacgaatcag attttttctt ttggttcttg gattcttcca ttgtttccaa
    24541 atatattgtc tgattcttcg cttcaaccaa ccgtttaact ccctcatgaa ttctttcatc
    24601 tcaccaattc catagtagtt gatccaacca gtcattagtt gcttgatttc ttttaaaata
    24661 agttggatac ttcttccacg gtttctttta gtgagttgtt tgagcttgct tttcacacgc
    24721 tgttttgctt ttgcgtgagg gcgaatttta atacctttct ttgttggcag aatgcagaat
    24781 ccaagaaact ttcgtttcaa tggacttcct accgcactct tttctcgatt taccgtcaac
    24841 tttagttgtt cttcgagaaa ttgaatggat ttcttcatca cacgctgtcc tgctcgtttg
    24901 cttctaacat agatattgca gtcatcggcg tatcgaacaa atttatgtcc tagattttct
    24961 agcacttgat caaattcgtt caggtagatg ttacttaaca ggggagagag attgcctcct
    25021 tggggcgttc cttcttcagt tgttgtgatg agtccatttt ccattacacc actcattaag
    25081 tattgacgga tcagttttag gacttgtttg tcctttactt tccgctcaat gaaatacatc
    25141 agcttatcgt gatttacggt gtcaaagtag gctttcatat caatgtccac cacatatcgg
    25201 taaccttgtt cataataaga ttttgctttc ttcactgcgt catgtgcgct gcgatttggg
    25261 cgaaacccat aactattatc tgagaattct ggttcaaata gcggttgtaa cacttgattg
    25321 attgcctgtt gaagcatacg atcaataacc gtgggaattc ctagttttct tacaccgccg
    25381 tttggtttcg gtatttctac tcgcaaaaca ggctgaggtt tatagttccc ttggcgtaaa
    25441 ttggatagta attcctcgcg gtgctctttc aagtaaggaa gcagttgatc gacggtcatc
    25501 ccatctgcac cagccgcccc tttatttctg actacttgaa gatacgcttg attgagatta
    25561 ttccgatcta gaattctccc aaacagattt tctacaccat cttgtttcct ctgttcaccg
    25621 caagaagtgc tgcgcacttc atcataccct tcgtgttcca cactagctct ttgatgatag
    25681 ccaagttttc ttgttttctg cggtcgtcgc atcttctcac acctcctaaa ttattcaaga
    25741 ttcttattgt tcagtccttc gtaacggtca gtgtcgttac tactatgacc tcggctgact
    25801 tctcatgatt caccatcatg tcgccatgat cgttgtgctg gtttgttttc attcaacgcc
    25861 cacaacaccc tcatgagatc tcccccggta agagtgaaaa ctttcctccc atgtaactgc
    25921 tagatttact gtataggttt cgggcagtat tggactttgt cttgtgatga agacttatcc
    25981 gacctaattc agccttgtat ctagtttctg ttcgtcagtt caggagtttg cgtccgactt
    26041 ccttcagcca caacctcacg attgccgcct tgtctttcgc taacagttcc tactgccaag
    26101 cctgtagtgg actttcacca ccaagttttc acccatgcag ggcgcacacc aaaaaagaag
    26161 cagatccgtt agcggttctg cttcttttag tttattatat tttcttatca ataataggaa
    26221 cctgatttta aaagcggcta cctctttacc gtgcctcttt acatacaaaa aatagaggaa
    26281 ttaagcgtaa atggcttggc tattataact aaaatgctgg ttatggagat gttgcagcaa
    26341 gttttcgaga aaagcgtatt ccatctcttg tccattgaat aagatctgga tacgataatg
    26401 atttttgaaa cgcttctgtt catgaatctg actgattgaa agttcgcctt tgtgttctgt
    26461 ctgataaaga aaagtccttt tacggcattc agcacagcgc ttggttgctc ggcggatttt
    26521 tcggaatgta taaaaactag tatctttatt gcataaataa acgtctttga tcgacagcaa
    26581 atcattatat agacaggaac gttcttcagc tgttaattct gataaaaaaa gctgaccttg
    26641 ttttattgca tcttccatcg gcaagtgcct cctcgaaccc attatccaaa tttttagtta
    26701 attctaatat accatcatta agtataaatg taaacgcttg ttgatggtat aagattttcg
    26761 tttctgataa aacacgaaca ttaaaagaat ctaatgcctt aaatgtacat atttttgttg
    26821 atttataaaa agatgattgc taaaatttaa agtgaaaaaa cgaacaaaaa acgatgtatt
    26881 tgcttttaat gtaaataaaa aggagagacg tacatggaga agaaagaact tttgtatgaa
    26941 ggaaaagcca aaaaaatata tcttacttct gatgagaact tgatttggat agaatattta
    27001 gatcaagcaa ctgcgttgaa tggcgcgagg aaagaccaga taagtggaaa aggagaattg
    27061 aataatcaaa tcacaagtgc aattttccgt tatctgactc aaagaggaat aaaaaatcat
    27121 tttattgaac aattgtctaa aaccgaacaa ttagcaaaaa aagtacaaat tatccctctg
    27181 gaagtggtta tccgaaatat tgcagcagga agtttctcaa aacgtctagg tgttcccgaa
    27241 ggtaaagaat tcatcaaacc aatcattgaa ttctactata aggatgacca gttggatgat
    27301 ccatttatca atgaagagca tatctatttc ttacaacttg caaagccgga agaaatcagt
    27361 gagctgaaag cccaagcgtt ggctattaat gaaattttga ccgaattatt tgctaaggtc
    27421 ggtttggttt tagtagattt caagctagaa tttggccggt cgaatggaca aattttgctt
    27481 gcggatgaag taacaccgga tacttgccga ttatgggatg aacgtacgaa tgaacatatg
    27541 gacaaagacg tttaccgcag agatctaggt gatttgatcc cagtctatca agaagtatat
    27601 aaccgtctat cggaactaac tgaagaaaag gagcgagtat gatgtatttc gtaaaagtat
    27661 atgtaaccta taaagattca gtgttagatc ctcaagggga ggcagtaaaa aaagcagtcc
    27721 atcgtatggg atatgaaaca atcgaagata tccgaatagg aaaatacttt gagatacaac
    27781 ttgctgatgc agaagaacca atcgatacag tgattgaaac gatttgtgac aagctgcttg
    27841 caaatgtaaa tatggaaaca taccgatatg aaatcaaaaa aatggaggaa gtataacatg
    27901 aaatttgcgg tcatcgtttt tccaggttca aattgtgacg cagatatgtt atgggcagtt
    27961 cgcgagatca tgggcgctga tgccgaattt gtacggcatg atgagtcctc tttagaagga
    28021 tttgatgggg ttttactgcc gggaggattc tcctatggtg actatttgag atgcggtgcg
    28081 attgctcggt tttctacaat catggaagaa gtgattcgtt ttgctgaaga agggaaacca
    28141 gtattcggta catgcaatgg attccagata ttgacagaag caggactttt gccaggtgta
    28201 ctgagacgaa atgagtcttt gcattttatt tgcaaaactg taccattgaa agtcaacccc
    28261 aagacggcct ttacttcaga gtatgaagcc gacgaaataa tctatcttcc agttgctcat
    28321 ggggaaggaa attatttctg tgacgaagaa acacttcaag aactaaaaaa aaataatcag
    28381 attgccttta cttataatga caacatcaac ggcagcgtgg aaaacattgc agggattacg
    28441 aacaaagcag ggaatgtgtt aggaatgatg cctcatccag aacgtgcagt agaagacttg
    28501 ctaggatcag aagatgggaa acggttcttt gcttccattt taaaaaactt cggaaaggtg
    28561 accgtataga tgaaaacatt gaaagaaccg acagctgaag agatcaagaa aaaaagaatc
    28621 tatgccgaat ggggattgac tgatgaagaa tatcgaatga tcgaagaaga tatcttagga
    28681 agaatgccta attatacgga aactggactg ttttctgtta tgtggagcga acattgttcc
    28741 tataaaaatt ctaaaccggt tctacgcaaa tttcctacta gtggacctca tgtgttgcaa
    28801 ggccctggag aaggcgcagg catcgtcgac atcggtgatg gactagcagt tgtcttcaaa
    28861 gcagaaagtc acaatcatcc ttcagccgtg gagccttatg aaggagctgc gacaggagtt
    28921 ggcggaatca tcagagatat tttcagcatg ggggctcgtc caattgcgtt gctagattca
    28981 ttgaggttcg gcgaattaga taatccaaga acgaaatatt tactagaaga agtagttgca
    29041 ggtatcggcg gatacggcaa ttgtatcggc ataccgactg taggcggcga aattgcattt
    29101 gatccttgtt atgaaggaaa cccattagtc aatgcaatgt gcgtaggttt gattgaacac
    29161 aaacatatcc agaaagggca agccgctggc gtcggtaatt cgatcatgta tgtaggtgca
    29221 aaaacaggtc gcgacggtat ccacggagca acttttgcct cagaagaatt taatcaagaa
    29281 gaagaacagc aacgttctgc tgtacaagta ggcgatcctt ttatggaaaa gctgctgctt
    29341 gaagcgtgtt tggaattaat cttgcatcat tcggattctc taataggtat acaggatatg
    29401 ggagcagcag gacttgtttc atctagtgcg gaaatggctt caaaagctgg ctcaggactt
    29461 atattgacat tagatgaagt cccacaaaga gaaactggga tgacacctta tgaaatgatg
    29521 ttatcggaat cacaagaacg gatgttgatt tgtgttaaat caggagagga agaaaaaatc
    29581 caagaactat ttcagaagta tgatctagat gcagtcacta tcggtaaagt aacagacgac
    29641 gggcaatatc ggctatatca tcaaggagaa gaagtagcaa atctgccagt cgatgcatta
    29701 gctgaagatg caccagttta tcataaagaa atgaaagaac cagctcgaat cgtagaattt
    29761 cagcagttag ctccttatca gccagttatc gaagaacctg gacaagtatt gcttgatctg
    29821 ctgcagcaac cgacgattgc ttcaaaacgt tcaatctacg aaacttatga ttcacaagta
    29881 caaaccaata cagttgtccg tccaggaagc gatgctgctg tgatgagggt tagagggacg
    29941 aataaagcgt tagctatgac cacagactgc aacgcgcgct atctgtattt ggatccaaaa
    30001 atcggaggac aaatagcagt ggcagaagct gctagaaata ttattgctag cggtggtaag
    30061 cccttggcga tcaccgactg cctgaactat ggttctcctg ataaaccaga agttttttgg
    30121 gaattatcga cttcagctga cggaattgct gctgcgtgtg aaacgttagg aactcctgtt
    30181 atttcaggaa atgtctcttt atataatgaa acggatggtc aagcaatcta tccaacacca
    30241 atgattggta tggtcggatt gattgaggat cataaacata tcactactca ggaattcaaa
    30301 aaatcagggg atctaatcta tatattaggt aagacgtttg cagattttga tggcagtgaa
    30361 ttacaaaaga tgcagcttgg aagaatcgaa ggtgtgatcc gaaactttga tctatccatt
    30421 gaaaagagaa accaagagtt agtattgaca gccatccaaa acggattgat tgaaagtgct
    30481 catgactgtt cagaaggtgg cttggcaatt gcactggcag aatcagcttt caaacatcag
    30541 ctagggatat ctgtacagtt tgaattgtcc tctgctcaat tatttgcaga aactcaatca
    30601 agatttgtgt tgacagtcgc accggaaaat aagacacgat tcgaagaaat gatgggagat
    30661 gctgctgttt tagcaggtaa ggtgacggat gaagcgataa tcgaaatttc agcaactgac
    30721 ggtcagatca aaatagaaac tgcagtagca agaaagtgct gggaggatgc aatcgtatgt
    30781 cttatgaagt gaagagttta aatgaagaat gcgggatctt cggtgtttgg ggtcatccag
    30841 acgccgctag tgtggcatac ttcgggctcc atagtcttca gcatcgagga caagaaggtg
    30901 caggtatcgt gtccaatgat cgaggaaagc ttaaggggca tcgagatttg gggctgcttt
    30961 ctgaggtatt caaagatcaa agaaaattgc agcagttaac aggagaagct gcaatcggac
    31021 atgtacgtta tgcaacagca ggcaatggaa gtgtggacaa tattcagcct tttctattca
    31081 aatttcatga tcagtcgatc ggcttagcgc ataatggtaa cttgatcaat gctcgttccc
    31141 ttagaaaaga gttagaggaa aatggggcga tcttccattc taactccgat acggagatat
    31201 tgatgcattt gatccgacga agtgaagaaa cagatttttt aaataaatta aaaagtgctt
    31261 tgaatgaagt caaaggtggc tttgcctatt tattaatgac agaaacggca atgattgccg
    31321 ctttggaccc aaatggtttt cgtccattag caatcggaca aatgaaaaac ggagcatacg
    31381 tgattgcctc ggaaacttgt gcattagaag ttattggggc acgttttata agagatgtcc
    31441 agcctggtga gatagtgatc atcaatgacg aaggaatcca gattgattgc tttacgaagg
    31501 acacgcagct ttctatttgt tcgatggaat atatctattt tgccagacca gattcaaaca
    31561 tcgcagggat caatgtgcat actgcacgga aaaatatggg acggaattta gcgaaagaat
    31621 cgccagtaaa agcagatatg gtcgttggcg tacctaattc ttctttgtca gccgcaagcg
    31681 gttatgcgga agctagtgga atcccttatg aaatcggatt agtaaaaaat caatacattg
    31741 cccgaacatt tatccagcca acgcctgagc taagagagca aggtgttcga atgaaattat
    31801 ctgctgtacg aggagtagtg gaaggtaaaa aggtgattat ggtcgatgat tcaattgttc
    31861 ggggtacgac aagcagacgg atcgtccatc ttttgaaaga agcaggggca aaagaagtcc
    31921 atgtgaggat tgcttctcct cctttgaaat atccatgttt ttacgggatt gatattcaaa
    31981 cgcgtaaaga actcattgcg gcaaatcaca cgattgatga aatcaaagaa tgtatcggtg
    32041 cagattcttt aggtttttta agtgaagagg gtctgatcga atcgatcggt ctggaaaaag
    32101 atgctccgta ttcaggattg tgtatggctt atttcaacgg agattatccg acgccgttat
    32161 atgactatga agaaaaatat caggaatcac taaaagaaaa agtatcgttc ttttaaaagc
    32221 agaccaagaa gggagtatat gaattcaatg gcaaatgcat acgcaaaagc tggcgtagat
    32281 gtcgaagctg gatatgaagt agtagaacgg atcaagaagc atgtcaaaaa aacggaacgt
    32341 ttaggtatga tgggcgctat aggaggattc ggcggttgtt ttgatttatc ggtctttcaa
    32401 ttaaaagagc cagtccttgt ctcggggacc gatggcgtgg ggacgaaatt agcagtggca
    32461 atcgaagcag acaaacacga tacaatcggg atcgactgcg tagcgatgtg tgtcaatgat
    32521 atcttagcac aaggcgcaga gccgttatat ttcttagact acttagcaac ggggaaaaat
    32581 gatccgttac gtttggaaaa tgtagtaaaa ggtgtagcag atggatgtgt tcaaggaaat
    32641 atggcgctga ttggcggaga aacagctgaa atgcctggta tgtactcagg taatgattat
    32701 gatctagccg gatttgctgt agggatagct gaaaaatctc aattattgac aggagaaacg
    32761 atcaacccag gagatgtgtt gcttggaata gcatctagcg ggattcattc aaatgggtac
    32821 tctcttgttc gcaaaatttt ctttgagcag cagcagtttt ctttatcatc aaaactgcca
    32881 gaattgaaaa aaacacttgg cgaagaattg cttgagccaa cgaaaatcta tgtttcttcc
    32941 ttgcttccgc tgatcaaaga aaagaaaata aaaggagctg cacatatcac tggtggaggg
    33001 tttgtagaaa atatcccgcg aatgttacca gaatctatgg ctgcacaaat caaacttggc
    33061 tcatggccga ttcttccaat attcggctgt ttacaaaaat atggtgaaat tcctgagatg
    33121 gagatgtatg aaatcttcaa tatgggcatc ggtatggtcc tggcagtcca agaatcgaaa
    33181 gtaaaagaaa tagtacacga aattgagcaa gctggcgaaa aagtttatga aatcgggaaa
    33241 gtgatcgcca aagaaaaaca tcgtgtggtg tttataggag aagaacgatg agaatcgctg
    33301 tttttgcttc tggaaacgga agcaactttc aagcgctagc cgattatcta tcgaaaaaag
    33361 gattggaatc ttcgattgac tggttgtttt gtgatcagcc tgaagcatat gttttgaaac
    33421 gtgcaactgc gttgagtgta ccggcagatt gtttttcacc taaagaattt gattcaaaaa
    33481 aagagtatga agaagcaatt ttgcataaat tgaaagaaaa aaagatcgat ttgatcgtat
    33541 tagctggata tatgcgaatc attggaccgg tattgctgaa aaattatgat aaaagaatca
    33601 tcaatatcca tccgtctctt ttacctgcct tccctggttt gcatggcata cgtgatgcct
    33661 ttgaagctgg agtaaaagaa acgggtgtca caattcatta tatcgaccaa ggtgtagata
    33721 ctggaccaat catccggcag gaaaaagtga gaattgaaca ggaggacacg ttcgattctt
    33781 tagaagaaaa aatccataga gtagagcatc gaatctatcc agaagtgatt agtgaaatta
    33841 ttgaaaatgg aggctatctg aaatgacaag agcattgatc agtgtatcag ataaaactgg
    33901 gattgtagca ttcgcccaag gtttgattga acaaggagta gaaatcattt caacaggagg
    33961 aacaaagcat gcgttggata aagctgggat caaaacgctt tcgatcgaag aagtgacagg
    34021 gtttcctgaa atgatggatg gccgtgtcaa aacacttcat cctaaaatcc atggtggtct
    34081 tttaggaaga cgcgatctcc ctagccatat ggaggcaatg gaaacggaaa atatccaacc
    34141 aatcgacttt gtttgtgtca atttatatcc tttcaaagaa acgattatga aaccagatgt
    34201 cgaaatagca gaagctattg aaaacattga tatcggtggt cctagtatgc tccgtagtgc
    34261 agcaaaaaac catgaatttg tcacctctgt tgttgatcca tctgactatg aagaagtact
    34321 ttcagaatta cgtcagtatg ggcatacttc actttctttc agacaaaaac tagcggcaaa
    34381 agtctttcgt catactgcgg catatgatgc actgatcgct caatacttaa cggattgggt
    34441 ggaagaaaaa gaaccggaaa aattgacact tacgtatgaa cgaaaacaaa cgcttcgtta
    34501 cggtgaaaat agccatcaag ccgctgcctt ttatcagtcc gctcttctgg aaaaatattc
    34561 gatcgcagca gcaaaacaac tccatgggaa agaactttct tataataata tccgagatgc
    34621 agatgctgcg ctacggatca tgaaggaata tgacgagcca acggtagtcg ccttgaaaca
    34681 catgaatcct tgtggtattg ggacagcatc tacgatttta gaagcgtggg aagcagcgta
    34741 tgaagcagat cctgtttcaa tctttggtgg gatcatcgtt ttgaatcgag aagtagatct
    34801 gccaacagca gaacagatgc ataagctgtt tctagaaatc atcattgccc cttcttatac
    34861 acaagaagct ttggaattac tgcaaaaaaa gaaaaacatc cgattactga cagtagactt
    34921 tgcgcaggaa gaaaatcaaa atcgagaaga aacggtctca gtcttaggtg gacttcttgt
    34981 acaagatcaa gatctggcaa tagaaaatga agaagagtgg aaagtcgtga caaaacgtaa
    35041 gccgactcca gcagaagcaa aagcattagc gtttgcttgg agagctgtca aacatgtgaa
    35101 atctaatgcg atcgtactgg caaacgaacg tcagacagta ggaatcggag ccgggcagat
    35161 gaatcgagtc ggttcagtaa aaattgcgat tgaacaagcg caagagaaaa tggaaggtgc
    35221 agttttagct agcgatgctt attttccaat ggatgattcg gttgaatatg cagccaaaca
    35281 tggtataaaa gcaatcattc agccaggagg aagcatcaaa gaccaagatt ctattgatat
    35341 ggcgaataaa tacgatctag caatggtctt tactgatgtt cggcatttta gacattagag
    35401 aggagtcgga taaatgaaca ttttggtgat cggtgcaggt ggtcgtgaac atgcaataag
    35461 taaaaaactt ttagccagtc cgaaggtgga tacggtgtat tgtgcgccag gaaatccggg
    35521 gatgacaaaa gatggtatca attgtgtcgc tatcagtgag cgagatcatt cagcgttaat
    35581 ccattttgtt aagaaagagg ctattgattg gagtatcgtt ggtcctgaag ttcctttgtt
    35641 aaatgggatc gtcgatgatt ttatggcgga aggattgaaa atcttcggtc cgacaaaagc
    35701 agcagctctg atcgaaggtt cgaaaagttt tgctaaacaa ttaatggata cttatcaaat
    35761 cccgacagct aaatccagaa gttttgaatg ttacgaaaaa gcagcagcgt atatcaaaga
    35821 aaatggtgcg ccaatcgtag tgaaagcgga cggcttagca gctgggaaag gtgtagtcgt
    35881 ggctaccaca gtgaaggaag cgctggatgc ggcagaacaa atgttgaacc agcatcgatt
    35941 tggggatagt agcaaaaaaa tcgtcgtaga agagtttttg gcaggagaag aattctccct
    36001 tttggcgttt gtccgtaata ccaaggtgta tccgatggtc atttcgcaag atcataagcg
    36061 ggcatttgat aacgataaag ggccaaatac aggcggaatg ggtgcttatt caccagtacc
    36121 gcaaatttca aaaaagatga ttgaaaaagc tgtggaagaa gttttaaaac cagcggcttt
    36181 gggaatgaaa gaactaggac gctctttcac gggtgtttta tatgcgggtt tgattgctac
    36241 gaaggaagga ccaaaagtga tcgaattcaa tgcgcgtttc ggtgatcctg aaacgcaagt
    36301 cgttctttct cggttgaaga gtgactttgc gcaagtaatc gatgatttat tagagaatcg
    36361 tacagtagag ttaaagtggc agcaagaagg atacaatgta ggcgttgtgg ttgcagctgc
    36421 cggttacccc gaagaatatg agacaggaat ggttctacca gattttctgg aagaagagct
    36481 ttctgtttac tatgctggag tttcctcaaa taacggcaaa ctagttggag caggaggacg
    36541 tctttattta gtagaagcat acggtgagac gatcaaagaa gcacagaaaa aaatttacac
    36601 cgcgttaatg gataaaacga cagatggaac attttatcgt acagatattg gagaaaaagc
    36661 tgccaatagc gaactgatcg tgaagtaaat cagctgcttc catttataaa aaatacaaca
    36721 aacataatcg gaagcgccga ttttagtgaa gccttttcat aaagagtgtg gtacactttt
    36781 gttgtgtata taaataagga ggagttcaga tgaaaaaaat tcaattaggt acttctgatc
    36841 agaaagcagc tgcagtgatc ttaggctgta tgcgtatcaa caatgcggaa gatccagtaa
    36901 aagtgattga gacagcttat gaaaacggca ttgatttttt tgaccatgca gatatttatg
    36961 gaaacggtga atgtgaagaa atctttgcag atgctctagc aaaaacatca atcaaacgag
    37021 aagatctttt tattcaaaca aaatgtggaa tcgttccagg tgtgatgttt gatttttcta
    37081 aaaaacatat cattgaatct gtagaaaaaa gtttgacccg tctgaaaatg gattatgtgg
    37141 atgctttact tcttcatcgt ccagatacat tggtagaacc agaggaagta gctgaagcgt
    37201 ttgatgaatt ggaacggtca ggaaaagttc gttattttgg cgtcagcaat caaaaaccaa
    37261 tgcaaatcga attgctgaaa aaatatgttc gtcaaccatt agtagctaat cagctgcaat
    37321 ttggcttgaa acatactgga atgatcgatc aagggattca tgtcaatatg acagatgaag
    37381 caagtatcga tcatgacggt agtgtacttg attattcccg attgcatgat atgacgatcc
    37441 aagcatggtc accataccag tatggatttt ttgaaggtgt atttatcggg aacgaaaaat
    37501 tccctgaatt aaaccaaaca ttagaagaac tagcagctaa atatcaaacg acaccaactg
    37561 gcttggcttc tgcttggatt ttacgccatc cagccaatat gcaagtgatc gccggtacga
    37621 tgaacgtagg gcgaatcaag gaaatcgctc aagcttcaga aattaatatg tctcgggaag
    37681 attggtacga attgtaccgt gctgctggaa acattttacc ttaaagattg tcataagcag
    37741 gtcaaaaggg ctataaatta aaaagacaga ataacttgaa agctgttttc agcttcgaga
    37801 tattctgtct ttttttattg caaatggaaa gagtatcatt gtacggattt cgtttattag
    37861 ttatttttgt ttttaaggaa aagctgtgtc cgatattctt ttggagaaat cccttgtttt
    37921 ttcttaaata aataactgaa atagttaggg tcattataac caatttcaaa agcaatatct
    37981 gaaatacgat agtctgattg ctgcaataat ttttttgcta attcgattct ttgttctgtc
    38041 agataatcga tgaatgtttg gttaaacgat tgagaaaaaa tcgtactgaa atgagaggga
    38101 cttaatgcaa cttgttgagc gacccaagtt aaggacatat ctggatcggt aaaattttct
    38161 ttgataaaat ccaatgcatg gttcaaaatt ggctgatatt tgttccttga aggctgtgag
    38221 ggcagagcag ttaagaaaga aatgaacata taaactgtcg aacggtaaag cgagtcgtcg
    38281 gcgctgattg ctaagcgttg actggtggat gtgcaatgaa ccatttcttg cgggattttc
    38341 ttttctttca ggcagacatg ctggagtagc ttagtcaaga caaataaacg atataatcgt
    38401 gttcgagttg gtgtgccttg tggtttcgtc aagtgttcga tgtacttaga tacttcgttt
    38461 ttcgataatg aagacaaatc aagtgagagg tcaaagtaaa agacagaatc aactggaagt
    38521 ttcgcttctt gaatcaaatc ctcatagctg ataatttgtt ctttaaggga actggcggtt
    38581 tcaagtatca tctgcgtgat ctcaaaagat gcaggtaatt cgctgattct ttctgcgaca
    38641 ggaccaatgg cgacagaaaa attatttttt tgtccctttt ctaattcatg gaccaacgtt
    38701 tgggctacct gataactggt ctcgatcaca ttttcttcaa gagaatcaac tattaaaaat
    38761 ttgatgaatc gagaggaaac agcagagaag atcacttgtt gattctccct aaataaaaac
    38821 ttcaaataat cactgagatg agcgtaatct tcaaagtctg tactgacttg gtttgctgct
    38881 aataatacgg tcattttttt ccctgctaaa gagcgattga aagattcagc aagtttcaat
    38941 gtttcactga tcgtaagtga gcctttgaac aaaccgttca agaaatgatt ttttttcaat
    39001 tcgaaaacaa gatcagaaga agtgtgcgtt tctttttgct gcaaatctaa agcagttact
    39061 gctttttcta ttgcttgttt caattcgcta cttttaatcg gtttaagcag ataatcatct
    39121 gcctgtacct ggattgctcc tttcatataa tcgaaatcgt cgaatccact aataaatatg
    39181 agacgagtcc aaggaagtag tttccttgct tcttttgaaa aagtcaaccc gtccatgaaa
    39241 ggcatttgga tatcagtcag aatgatgtcg ggctgtaagt cgataattga agacagtgcc
    39301 atctcaccat ctccagcttc gccgacataa gtgattggat aataagaacc aaggacagtt
    39361 atttgttccc gcaagttatt gcgaatgagg tattcgtctt cgatgataaa aactttatac
    39421 atgtttgttt cctccaattg ttttgggaga tagagggatc atcagtgtga cagttgttcc
    39481 ttctcggtat ttgctgtcaa tcgtgatagg tttttgatca tttccgtaat aaagaaggag
    39541 acgcttgttt acgttgtaaa gtccgtagcc gatactgaaa tctgaatcga tccctttggc
    39601 taactcttta cgtatttctg ccagtttttc tgcagggatg ccaatcccgt tgtctataac
    39661 tttgaattgg atcatctcat caattttgca tgtggtaata cgaataaatc ctttgtgacg
    39721 gacgtacttc gttccatggt atacagcatt ttcaatcaat ggctgcaaga tcatttttaa
    39781 aatagaaaca ggaaaaagtg tttctggtat atcgatctta tagtcaagca tatggccgta
    39841 tcttattttt aagatgacta gataatcatt gatatggcta atttcttttt caagaggaat
    39901 ccagtcttgt cctttgctta aagacgtacg aaaaaagccg gaaagtgcat gggtcatagt
    39961 cagagcttct tcaaagcagt cttgttcgat caaagaaata atggcatcca aactgttata
    40021 aataaaatgg ggagtaatct gagcttgcaa tacacgaact tcactttgtg ctaaatggta
    40081 ttgtttcaaa gcgttctccc gtaaagactg gtttagatct tccgccattt tattcatgct
    40141 agcggtaagt gtttgtaatt ccagtgtttc cggcagggtt aaacgaaagc caaggttccc
    40201 tgaagaaagt tgttctgaca tctcgatcag ctgattgatc ggttcttgga cctttctctc
    40261 taaaaagcga cgattctttt tcgcatagaa aaaaatggta ctaagaactc caagttccac
    40321 tattgttaat agaatgagcg agcggacaag tgtcgtattt tttttgcttg ctaagtcgat
    40381 ctccacacga acaaaatctt gtaagatatc tgacagcagt tgagtgacag aatctacctg
    40441 attgatgatc tcttcattgg tatccataaa atcttttgcc aagatattat tgatcagctc
    40501 gttttgataa tcttccagtg tatcgatcgt acgtagcgat acatctaacg tactaatttc
    40561 tttaagtgta tttgtattat ttttgatctc tcgaatatca ttcctaagtt cttctaggat
    40621 attttcctca ttgaactcat ctacggttac ttggccagaa atcaagtccc acatactttc
    40681 caaaactttt tgatcaacct tcaaagcaat tgcatctgct ttttggatat ttgcgatcgt
    40741 ctgttgataa atcaaaagct gttgcgaata taacagtatg ctcagtagca aagggataac
    40801 agcaaataga agcatggctt tgtttgcttg ggcaaaaatc tgttttatgc ttaaattttt
    40861 tgtcatgata cttctccagt caataatttc tggttgggat gttagctata ttctgctggg
    40921 aaaagacagt ctcggaaata aaaatatctt taggtaatgt ttttcctgtt tgaatatttc
    40981 caaaataacg agtaacggta ttggctacat accagccgac atcaggttta cactcgacta
    41041 cacaattgac gattcctgag cgtagcttct cgatcatatc ttcttgtcca tcaatagtta
    41101 caatgatcaa atcttctcca ggtttgattg atgtttcttt tatcgcagct aaagcaccgt
    41161 gagtcatttc atcactatgg ctgtataata catcgatttc ggataaatca tttgtttcta
    41221 aatatcgttt catctggtct tttcctttca tccgaataaa atcaccgaca attcggtgaa
    41281 caatagtcat cggaggttta tggtcgatgg ttccatcttt ttttagggtt ggtttacgat
    41341 tgattgattc caaaaatcct tcggagcgta gcttggtcgg tgtggagttc tctgaaccag
    41401 caagttctag gattctgatt tcctgtttct ttgaatttgt gaagtgattg ctgacaaata
    41461 aacccgcccg atttccttct gctttgaaac tggggccaat gtgggtgacg aaaagctcgg
    41521 gatcattcgt ttgaatatgt ctgtcgacaa gtatgacagg gatccctgct cgctttgctt
    41581 cttttaatac agagtcccac ccggattctt gcaaaggagt aaaaatgatc atatccactt
    41641 tataggcaat gaacgtccgt atatcttgga tttgccgttc ctgattcatg tagccatttc
    41701 ggtagagaac ttggtaatct tctttttcaa gcgcagtgat aattgattca gtatgctttt
    41761 tccgccagct actctccgtt cctgattgcg aaaaaccaac gactagtggg tcaggtgctt
    41821 cctttgtatt aggtgtacac cccatcattt ggtaagcgat tacaacaagg gctaaaaaaa
    41881 ataaaacacg tttcacttta aatcactcca tctggatttg ttagtactat cttatcagat
    41941 aaaagggaaa atcaaagtca aaaggaatca atcgaaaaaa atccaagaaa cttaaaaaaa
    42001 tccaagacaa aaaaagtaca cctaaaaaat ttaaagtaaa tcccataaaa aaatcaatgt
    42061 taacgctttc tttattagct atactcggtg tatcaattga aatgggggat aaaaaatgaa
    42121 aaacaaattt agaaagattg ttgggactat cgctattttg accgcaagca ttctattaag
    42181 tgcgtgtggc aattcaggat ctgcagatga tagtacgggg tatgtaggaa tcgctatgcc
    42241 gaccaaatca gcagaaagat ggatcgctga tgggaacaac atggtctcgg aattagaaaa
    42301 actgggttat aaaacagatc ttcaatatgg agaagataaa gtagaaaatc aagtagcaca
    42361 aatagaaaat atgattacaa aaggggtaga tacacttgtg attgcttcta tcgatggttc
    42421 ggctttaact gatgtgttag ctaaagcaaa agaagcagat atcaaggtga tcgcctatga
    42481 tcgtttactg atgaattcag aaaatgtcga ttattacgcg acttttgata attttggagt
    42541 aggtgtatcg caagcagctt atattgaaga gcacttagga ttgaaagaag gaaaaggacc
    42601 attcacgatt gaattatttg gtggctcgcc tgacgacaac aacgcactaa tcaattacaa
    42661 cggagtgatg tctgttttac aaccatatat ggacaacggt cagttggtcg tgccatctgg
    42721 acagacgagt ttcagtcaaa tcgctacgct tcgctgggat ggttctacgg cgcaagcaag
    42781 gatggataat ctgttaagcg caaattatac tgaccaaaca ttggatgctg ttttgtcgcc
    42841 atatgatcca ataagtttag gaatcatttc gtcattaaaa ggcgtggggt atgggagtga
    42901 aagtaaacct ttacctgtga ttactggaca agatgcgaca gttgctggcg ttaaatcgat
    42961 cattgccggg gaacaaacac aaacgatctt taaagacaca cgtatcttag caaaaaatac
    43021 gattgaaatg atcaaagcaa tcagtgatgg agaagaggtt ccggtcaatg atactgaaac
    43081 ttatgataat ggggtgaaaa ctgtccctac gtatttagca aatacagtat ctgtcgataa
    43141 agataattat caagcagagc tgatcgacac cgattattat aaagaatccg atctgaaaaa
    43201 ttaagaggaa ccaaacaagg aactaaagag atctaagtca gagagaggat aagaattatg
    43261 gcggattgta ttttaaaaat ggcagatatc accaaaaaat tttctggaat ccgagcgtta
    43321 gattgcgtga atctgatgat tgaacgtggg gaaatccatg cattgtgcgg agaaaacgga
    43381 gcgggaaaat caacattgat gaatgtcttg agcggcttgt atccatatgg ctcctatgac
    43441 ggggaaatct tttatgatgg aaagctgtgt caatttaaag atttgaaaga tagtgaagaa
    43501 aaaggcatcg tcatcattca tcaagaatta gcactaagtc cttatctttc aataaaagag
    43561 aatatttttc tcggaaatga acaagcagaa agaggcgtga ttgattggga actgacagaa
    43621 aagaaaacat atgaactgct gaataaagtc ggtttgtcta tcgacccgaa tcttctagta
    43681 tcccagattg gcgtagggca acagcaacta gttgaaatag ctaaagcatt atcaaaatcc
    43741 gtccgtctgt tgattttgga tgagcctacc gctgcattga atgaagaaga aagcgcgaat
    43801 ttgctgagat tgatccgaga gttgaaagag caaggtgtaa cctccatcat tatttcacat
    43861 aagctgaatg aaatcgtgga tatcgcagat cgaatcacca ttttacggga tggacagacg
    43921 attgagacac tagaaaatga aatgatcagc gaagagcata ttattcgcgg aatggtgggc
    43981 agagatttag ttgatcgtta tcctgaaaga aaaccggata ttggagaagt ttattttaaa
    44041 gtagaagact ggacggtcta tcaccctctt gatcacgagc gaatcataaa cgaccacatc
    44101 aacttgcatt tgaaaaaagg agagattgta ggaatagctg gactgatggg agcgggcaga
    44161 actgaattcg ctatgagtct atttggacat tcttatggaa gcaagatatc cggacgtata
    44221 ttaaaggaag gggcagagat atcagttaag accgttcctt cagccattgc aaacggactc
    44281 gcttatgtct cggaggaccg aaaatcttta ggactgaatc tgctgatgga tattcgggaa
    44341 aacgtgacgc tgagcagttt ggataaaata agtcaaaaag gagtattaga taaagaaaaa
    44401 gaagtaactg aggcagaaaa tttccggaaa aagatgcgta taaaaacaaa ctccatccat
    44461 caaattgtca gtagtcttag tggtgggaat caacaaaaag tcgttttatc caagtggctg
    44521 atgacacaac ccgatattct ttttttggat gagccaaccc gtgggataga tgttggggca
    44581 aaatatgaga tctacacgat tatcgaagaa atggcagcaa atggcaaagc tgtctgtctt
    44641 atctcttctg aacttcctga aatattaggg atgtgtgatc gaatctatac gatgaacgaa
    44701 ggacgtatta caggagaagt ctcgcgagaa gatgcagatc aggaagtctt gatgaaatta
    44761 atgacgaaag aagaggtggg ttaagttgga acaggcaaaa aatcttacgg ataaaaaaga
    44821 gaaaaaacta aatttgaaaa gtagagcagc tgatcttttt ggtcgctaca gcatggtgat
    44881 cattttagcg ggactactta ttgcgtttca attgatgacg gatggtattt tctggcgtcc
    44941 attgaatata actaaccttg ttctgcaaaa tagccatata ttagtactag ctgcagggat
    45001 gttattagtt gtgctcttag gtcatgtgga tttgtcggta gggtcagtga tggcgtttgt
    45061 tggtgcaatt gcgggcatga tgatggtcaa tcgccaaatg aacccgtgga tgacagttat
    45121 cgcatgtctt gcagtaggcg ggctgatcgg cgcatggcaa ggtttttggg tagcttatgc
    45181 agggataccg gcgtttatcg tgactttagc aggattgctg atgtttcgtg gactgacaca
    45241 agttgttcta ggaggccaat ctctagcacc ttttccagct gttttccaaa aaatgtctac
    45301 gggttattta ccagacttaa gcgaaggaag cagccttcac ttcttgacat tgattttagg
    45361 aatgatcatc acgatcgtgt tagttgttgg tcaatggcga acaagaaatc gtcggaaaaa
    45421 tcatttattt gaagtggaat ctccaacagc tttcttggta aaggcggtat ttacagcagt
    45481 cgttgtacta ggaataactt atatctttgc ctcttatcaa gggtatccga ttattttgat
    45541 cattcttggt ttgatcgttg cagcatatgg gtttttgaca aataaaacag tagcaggtcg
    45601 acagatttat gcgacgggcg gaaatcgaaa agcggctgaa ctatcaggga tcaaaacaaa
    45661 gcgaatcacg ttctgggtat tcgtcaacat gggagtcatg gcagctttag ctggattagt
    45721 tttagctgct cgattgaatg cggcaacacc tcaagcaggt acatcgatgg aactggatgc
    45781 aatggcggca gtatattttg gtggtgcttc gacttccggc ggcattggaa caatcatggg
    45841 tgcgattgtc ggtggcttgg tcatgggtgt attgaacaat ggcatgtcga ttttaggcgt
    45901 cggggtagac tggcagcagg caatcaaagg attgatcttg cttttagccg ttgtgctaga
    45961 cttgtataat aagaaaaaac gaacaacgta ggagaacgcc ggttattcag aaaaaagact
    46021 gtgacaagac atttgtcaca gtcttttttt cgctaaaagc gaacattcat tgtttcgttt
    46081 gtatagacta aaaataatat atgttttttt accattcgta taaattctct ttttgctctt
    46141 gatttttttg cttaattgag ttaaattaca tagggcgcta aaaaaagcct tgattaaatt
    46201 aataatgttc gtgttttgct ggatgtgaac atcaggagga taatgtaatg aaagtatttg
    46261 attacgaaga tattcaatta attcctaata aatgtatcgt aaatagccgt tctgaatgtg
    46321 atacaacggt cacattaggt aaacatacat tcaaaatgcc agtagtgcct gccaacatgc
    46381 agacgattat tgatgaaaca atcgcagaat tcttagcgga aaatggttat ttctatatca
    46441 tgcatcggtt tgatgaagca gctcgaattc cgtttatcaa aaaaatgaaa aagcgtggat
    46501 tgattacctc gatcagtgtt ggcgtcaaga aagaggaata ttcctttata gagaagttgg
    46561 cagaagaatc gctaaatcct gattatatca ctatcgacat cgcgcatgga catgctaact
    46621 cagttattga tatgattcag catattaaaa aatatttgcc tgaaactttt gtgattgccg
    46681 gtaatgttgg tacaccggaa gccgtccgtg aattggaaaa tgcgggcgca gatgcaacaa
    46741 aagtcgggat tggtccagga aaagtatgta ttacaaaaat caagacaggc tttgggactg
    46801 gaggctggca actggcagct cttagatggt gtgcgaaagc agctcgcaag ccgatcatcg
    46861 ctgacggtgg gatcagaaca catggcgata ttgcaaaatc tgtccgtttt ggtgcgacaa
    46921 tggtcatgat tggttcattg tttgccggtc acgaggaatc tcctggcgaa acaaaagtcg
    46981 aaaatggaat cgtgtataaa gaatactttg gttctgcttc agaattccaa aaaggcgaaa
    47041 aacgaaatgt tgaaggaaag aaaatctgga tccaacacaa aggatctttg aaagatacac
    47101 tagtggaaat gcaacaagac cttcaatcat ctatttctta tgctggagga agagatctgg
    47161 aagccattcg aaaagttgac tatgtc
//
LOCUS       DACGEU010000011        44878 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.011, whole genome shotgun sequence.
ACCESSION   DACGEU010000011 DACGEU010000000
VERSION     DACGEU010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 44878)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44878)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44878
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.011"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..1008)
                     /locus_tag="IXR40_000594"
     CDS             complement(<1..1008)
                     /locus_tag="IXR40_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAQ4360467.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(1188..1532)
                     /locus_tag="IXR40_000595"
     CDS             complement(1188..1532)
                     /locus_tag="IXR40_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HAQ4360468.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(1525..1959)
                     /locus_tag="IXR40_000596"
     CDS             complement(1525..1959)
                     /locus_tag="IXR40_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HAQ4360469.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            2097..2834
                     /locus_tag="IXR40_000597"
     CDS             2097..2834
                     /locus_tag="IXR40_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4360470.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            2827..4038
                     /locus_tag="IXR40_000598"
     CDS             2827..4038
                     /locus_tag="IXR40_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4360471.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            4245..5024
                     /locus_tag="IXR40_000599"
     CDS             4245..5024
                     /locus_tag="IXR40_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HAQ4360472.1"
                     /translation="MEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAAL
                     SREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLKT
                     MLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHGD
                     VNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDEM
                     LEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            5094..5756
                     /gene="trmB"
                     /locus_tag="IXR40_000600"
     CDS             5094..5756
                     /gene="trmB"
                     /locus_tag="IXR40_000600"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HAQ4360473.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(5854..7608)
                     /gene="ade"
                     /locus_tag="IXR40_000601"
     CDS             complement(5854..7608)
                     /gene="ade"
                     /locus_tag="IXR40_000601"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HAQ4360474.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNNQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            7740..8669
                     /gene="cpaF"
                     /locus_tag="IXR40_000602"
     CDS             7740..8669
                     /gene="cpaF"
                     /locus_tag="IXR40_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component"
                     /protein_id="HAQ4360475.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLRLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            8626..9675
                     /locus_tag="IXR40_000603"
     CDS             8626..9675
                     /locus_tag="IXR40_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGB"
                     /protein_id="HAQ4360476.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            9672..9950
                     /locus_tag="IXR40_000604"
     CDS             9672..9950
                     /locus_tag="IXR40_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HAQ4360477.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            9925..10395
                     /locus_tag="IXR40_000605"
     CDS             9925..10395
                     /locus_tag="IXR40_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HAQ4360478.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            10412..10714
                     /locus_tag="IXR40_000606"
     CDS             10412..10714
                     /locus_tag="IXR40_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360479.1"
                     /translation="MESLTALMIASVCVYLVSFGQLFLLQAEKKSGEELLFIRMIYED
                     IKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAISIEKTSNSSIYAD"
     gene            10731..11102
                     /locus_tag="IXR40_000607"
     CDS             10731..11102
                     /locus_tag="IXR40_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComGF family competence protein"
                     /protein_id="HAQ4360480.1"
                     /translation="MILSSLLLTFNLLIQQTIQVSEFLQRKDQKEWLIFLAQLEEELK
                     SSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQPMLTSITELQLLEKEHTI
                     SFYVHFENGEDGYAIWTKNDQ"
     gene            11074..11433
                     /locus_tag="IXR40_000608"
     CDS             11074..11433
                     /locus_tag="IXR40_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360481.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            11605..12612
                     /locus_tag="IXR40_000609"
     CDS             11605..12612
                     /locus_tag="IXR40_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAQ4360482.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            12637..13821
                     /locus_tag="IXR40_000610"
     CDS             12637..13821
                     /locus_tag="IXR40_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HAQ4360483.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(14258..15841)
                     /locus_tag="IXR40_000611"
     CDS             complement(14258..15841)
                     /locus_tag="IXR40_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAQ4360484.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(16419..16562)
                     /locus_tag="IXR40_000612"
     CDS             complement(16419..16562)
                     /locus_tag="IXR40_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HAQ4360485.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(16785..17264)
                     /locus_tag="IXR40_000613"
     CDS             complement(16785..17264)
                     /locus_tag="IXR40_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAQ4360486.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(17337..17621)
                     /locus_tag="IXR40_000614"
     CDS             complement(17337..17621)
                     /locus_tag="IXR40_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360487.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(17699..17893)
                     /gene="ssrS"
                     /locus_tag="IXR40_000615"
     ncRNA           complement(17699..17893)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="IXR40_000615"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(17965..19251)
                     /locus_tag="IXR40_000616"
     CDS             complement(17965..19251)
                     /locus_tag="IXR40_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HAQ4360488.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            19389..20060
                     /locus_tag="IXR40_000617"
     CDS             19389..20060
                     /locus_tag="IXR40_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HAQ4360489.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            20026..20514
                     /locus_tag="IXR40_000618"
     CDS             20026..20514
                     /locus_tag="IXR40_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HAQ4360490.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            20527..21474
                     /gene="prmA"
                     /locus_tag="IXR40_000619"
     CDS             20527..21474
                     /gene="prmA"
                     /locus_tag="IXR40_000619"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HAQ4360491.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            21475..22239
                     /locus_tag="IXR40_000620"
     CDS             21475..22239
                     /locus_tag="IXR40_000620"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HAQ4360492.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            22472..24685
                     /locus_tag="IXR40_000621"
     CDS             22472..24685
                     /locus_tag="IXR40_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HAQ4360493.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            24696..25142
                     /locus_tag="IXR40_000622"
     CDS             24696..25142
                     /locus_tag="IXR40_000622"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HAQ4360494.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            25313..26572
                     /locus_tag="IXR40_000623"
     CDS             25313..26572
                     /locus_tag="IXR40_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HAQ4360495.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(26661..27608)
                     /locus_tag="IXR40_000624"
     CDS             complement(26661..27608)
                     /locus_tag="IXR40_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HAQ4360496.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNSRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            28002..29294
                     /locus_tag="IXR40_000625"
     CDS             28002..29294
                     /locus_tag="IXR40_000625"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HAQ4360497.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            29309..31078
                     /gene="aspS"
                     /locus_tag="IXR40_000626"
     CDS             29309..31078
                     /gene="aspS"
                     /locus_tag="IXR40_000626"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HAQ4360498.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            31187..32062
                     /locus_tag="IXR40_000627"
     CDS             31187..32062
                     /locus_tag="IXR40_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAQ4360499.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            32328..34211
                     /locus_tag="IXR40_000628"
     CDS             32328..34211
                     /locus_tag="IXR40_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HAQ4360500.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(34286..34570)
                     /locus_tag="IXR40_000629"
     CDS             complement(34286..34570)
                     /locus_tag="IXR40_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HAQ4360501.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(34560..35294)
                     /locus_tag="IXR40_000630"
     CDS             complement(34560..35294)
                     /locus_tag="IXR40_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HAQ4360502.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            35423..36046
                     /locus_tag="IXR40_000631"
     CDS             35423..36046
                     /locus_tag="IXR40_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HAQ4360503.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            36238..37359
                     /locus_tag="IXR40_000632"
     CDS             36238..37359
                     /locus_tag="IXR40_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HAQ4360504.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            37366..40494
                     /locus_tag="IXR40_000633"
     CDS             37366..40494
                     /locus_tag="IXR40_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HAQ4360505.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            40513..43707
                     /locus_tag="IXR40_000634"
     CDS             40513..43707
                     /locus_tag="IXR40_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HAQ4360506.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(43853..44560)
                     /locus_tag="IXR40_000635"
     CDS             complement(43853..44560)
                     /locus_tag="IXR40_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HAQ4360507.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
BASE COUNT        14403 a         7967 c         9410 g        13098 t
ORIGIN      
        1 ttttgatgaa tcagttgttt cttcagttga agattctttt gttgaatcag ttgattttgt
       61 gtcagaactc tttgttgaag ctgtagtttc acttgagtct ttcgtacttg atgaagttgt
      121 tgtgaatgca ctcaacacat tttcaaaggc atcatctttg atttttacat ttgcatcttt
      181 taattcttca ccgattactt tagttgtgaa tgcattgtca cttagtttag tttcagtagc
      241 gatatctttt agttgatctt tgtatttatc catgtcattg cctttatttt ggtttttcac
      301 cattttgaca acgtagtatt ctgtcgcata agaagtagga tttgttgtag taataacatc
      361 ggagatctca ccgtctttca atttgaaagc tgcttctttt acttctgcag gaatagttgt
      421 tgtcgttgag tcgaatttaa ctttaccgcc atcttctttt gtctctgtat cagttgattt
      481 gtctttggct aatttagaga aatcatctcc atcatccgct gattttttca catcttttgc
      541 ttcatcttca cttgataatt tgatgatttg tgcttctact tctggatgga aagatttcca
      601 agcagttttc aaatcgtcat ctgtaatatc tacgtgagct ttcaagccag cttcaaaagc
      661 taaattgtta cgaatatatt ctttataagt atctttcgta tatccagcag cttctaattg
      721 tgattcaaaa gtatcaccta atgatttcgc ttgtttgtcg tattctgcat ccacttgctt
      781 atcggttact ttatcgccat atttgttatt gaatacttta taaatgatca tccgttgtac
      841 taaggattgg ttcgatgatt caagttttgc ttcatcatag aaatcagata cagtgatcgt
      901 tccgcctttc atcgttgcga tatctttatt agtatcgcct gaacaagctg ctagagttaa
      961 aacagccaac gcactagtag ctgccaaaat aattgatttt tttttcatta aaatttgcac
     1021 tcctgtaatt agttattatt tttatatatt aactatacca tatcccattt cctttaaaaa
     1081 cgttgtcgtg gtagtttcaa acaaaattca aaatttcatc acattcctag gaaatacgca
     1141 aacttttctc acttatatag ttaaatctgt tgagaaaata atcattatta tatttgttca
     1201 ggatactctg gcagatcagc ttttagtttt tctacttgtt cattgatttg tgtgatacgt
     1261 ggttcggctt ggaatttaaa atcttcgata tcttttttga ttgcttcttg gaaagcagga
     1321 atcacagatt cagctgtttc ttttgtttcg atcaatgcgc ttttaaaatg attcaggctg
     1381 ttatttaaat catttgtcag agttgttgct tcttccaatt cttcgatcag tttctttctt
     1441 gtttcattcc cgctcctggg cgccaataac agacctccga cagtgccagc agcagctcca
     1501 aataacagtc ctttgaaaaa gtttttaatc atcgcaggac acctgcttta cgattgtttc
     1561 ttgaatagct tttagttctt ccgatccata actatcttga tgattgacaa agtgaataga
     1621 aaaatcatcc tctttgctgt agcgagggac taaatggata tgtgaatgaa aaacagattg
     1681 ataggctagt tcacggttgt tattcaagat attaagacct ttcatttctg gaaaagcttt
     1741 ttccaatgct tgagcaatct taggcacacg cgaaaaaacc tctcctgcaa gttcgggatc
     1801 atattcaaaa atatctgcta catgacgttt aggcacaact aatgtgtgtc ctttcgttgc
     1861 ttgagagatg tctaaaaaag catagacctt gtcgtcttca tatattttat agcttgggat
     1921 ttcttgattg atgattttgc aaaaaataca gttttccata taaaacatcc tttctataaa
     1981 gaataaatac ttcagcttaa ctttaccata agttaaagct attgtaagga aaaaaacaaa
     2041 ataccgtcat tttcttcgtg gtataataaa taaaaataaa tggcggagga aaaagaatga
     2101 gtttaattat cgatcatgtc acaggggggt acggacatct ccctgtgtta aaagatatca
     2161 gtttcgatgt acagcctgga gagatagtag ggttgattgg actgaacgga gcagggaaaa
     2221 gtacgaccat caagcacatt atcggtctgc tggaagcttc aaaaggaacg atagaaatca
     2281 atcatctatc cttaaagaaa aatacggaag aatatcgcaa acaaattggg tatattccag
     2341 agactccttc tttatatgaa gaattgacat tgagagaaca tatcgaagtc actgcgatgg
     2401 cctacgatat acctatggat atagcaatga aaagagcaga aaagttgttg gagacttttc
     2461 ggttatctaa tcgtcttgac tggttcccag ctaatttttc aaagggaatg aaacagaaag
     2521 tgatgatctt atgcgccttt ttgatcgagc cttctttata tatcatcgac gaaccatttt
     2581 taggcttgga tccactagct atcaatgcat tgcttgaatt gatggtagaa atgaaaaaag
     2641 aaggagccgg tattttgatg tctacgcata ttttagctac tgcagaaaaa tattgtgatc
     2701 gttttgtggt cttacataac ggagagatac gagcagacgg ttctcttgag atgttgagaa
     2761 aagaatttca gctgccggat tcttctttgg acgaaatcta tattgcttta acaaaggagc
     2821 aggcacatga gtagtttttt tcaaaaacgt ttagcaagac atcaaaagaa aatgatgaaa
     2881 tatatgcgtt atgtattgaa cgatcatttt gttttagttt gtcttttctt gattggcggt
     2941 gtgggattat attattctaa ttggttgaaa accctgcagc caccgtttgc aattggaggg
     3001 ctcataatct ctgtattttg gatgctctgt ttattcgtgg gtaagatggc tacttttgca
     3061 gaggcagcag atattgtttt tttacttcct aaagaaaaag aaatgcaaac ctatttggaa
     3121 cgagcttttc gctattcttg catttttccg ttgatctttt tgatattggc atgcggattg
     3181 gccatgccat tagtggtggt tagtacggag caatcctttt cgatgttttt cgtctatctg
     3241 atcatattat ggagtttgaa attcagtcat ctgcaaatca agagagcaga attgtttcga
     3301 ctagatcaac aagttattcg ttattggaaa ttaggctggt ttttttcttc tctgatcttt
     3361 ttgtttctat cattttattg gctaatatgg gcaggaatag caggtgcatt agtacaggca
     3421 agtctatatt actggttttt gtggaagcaa caagaaaaag gattggattg ggagaaaatg
     3481 gtgcatgtag aagaacatag gttgcatcag atctatcaat ttatcaattt attcacagat
     3541 gttcctgaaa ttacggcaaa gatcaaaaga agacgctatt tggatcctat attgactcat
     3601 attaaaagag aatcaaaaaa cacttatctt tacttgtttg caagaagatt ggcaagaggt
     3661 tctgatttta gtggtcttta tttccgatta gtaattatag gtgggttatt gattgccgga
     3721 gtagtcgact tttattttag tctgattatc ggtttcttat ttttatattt gatcggtttc
     3781 caactgttac ctttagcgaa ccagttccgc tatatggttc tcgttcagct ttatccaatc
     3841 cataagaatc agaagaagca ggcgattcag tatctactca catgggtatt aattatcgcg
     3901 tcggttattt ttggtttgat tgctgcagtc gtattagatg ggcagcagcg atgggttccg
     3961 ctagcggctt atttgattgt tactatgctc tttgttaaac tatatgtacc aactcgtttg
     4021 aagaagatgt cagactgaaa acaaagctgt gtagggtaaa aatgagaatg aaaaatagag
     4081 cgttgacagt aagaatgctg ttcgttctat tttttttgag aaaagctggt tttttgaatg
     4141 gcaattaaat gaaaaagaac gtatatgtgc ttgacgtgta gtgttcaggc gactagaata
     4201 ataagtactg caaaacaaag agtaagagga cgggagaatg catgatggag tttcagttag
     4261 accaagagtg gcggttacgt cccatcaaag gcgacacagg aaaaacatac ataggcatgc
     4321 gtgatgagga caaagtcttt attaaacgaa acacgactcc gatgttggct gctctttcaa
     4381 gggaaggaat tacaccaaaa cttgtttgga caaaacgaac ggggaatggc gatactttga
     4441 cagcacaaga gtggctggaa ggtcgcttgc tgactcctaa tgagattggt caaagaaacg
     4501 acgtgattga tgttttgtac catttacatc attcaaattc tcttaaaacc atgctgaccc
     4561 gtatcggtgg tcgtgtcatg acgccggaga agatgctgca aaaatatgaa aaagaattac
     4621 cggaagaact ccagaaaaat caatttctgc aaattgtcca tcgttttctt cgtgagcaga
     4681 tcccgtcaat agataaggaa aacttatcag tagtacacgg agatgtaaac catcgtaatt
     4741 ggttagtatg taaaaattat ttatatctag tcgattggga ttcaatcatg tttgcagacc
     4801 ctgcggtgga tattgcaacg attttaggaa attatgtgcc actgtctagc tggaatcagt
     4861 ggctgatcag ttatggcata cgcccgactg acgaaatgct tgaaaaattt cattggtatg
     4921 cggccatgaa tttgctccaa gaaatcacca gatattgcaa acgtgaagat catcgacgga
     4981 tgaacgaaga aattttacaa ttaaaacgaa ttttcagtgg ctgaggtttg gcccaaactc
     5041 tgcggagatt tggccagacc tttttaatta gaggaaagga atggagataa ataatgcgtg
     5101 tccgaaatcg tccgggagca gcggaaatgt tagcggctca cccgaatttt gtaattagtg
     5161 atccaacatt gtggaaggga aaatggaatg aattgtttga aaacgatcat ccaatccaca
     5221 ttgagattgg tatggggaaa ggccagttca tcactggaat ggcaaaagcc catcctgaaa
     5281 tcaattatat tggagtagaa atgcaggtca gtgttgtttc gattgcacta gacaagttga
     5341 tcgaacaacc gcttcctaac ctgaaacttc tacatgtgga tggatcagcg ttgacagagt
     5401 atttcgctga cagcgaagta gatcaaatct atctgaattt ttccgatcca tggccaaaaa
     5461 aacgtcatga aaaacggcga ttgacatata agacttttct tgctgtagat gaacagattc
     5521 ttcgtccaaa tggagaaatc catttcaaaa cagataatca aggattgttt gagtattctc
     5581 tggcaagttt ttctcaatat ggcatgatcc tcaaacaggt atggttagat ttacatcaaa
     5641 gtcaatttga aggcaatatt atgacggagt atgaagaaaa attttcttca aaaggtcaac
     5701 gtatttatcg agtagaagct caatttcaag ataagaccaa aaagaaaagt ctgtgaaact
     5761 aactttctgc tttcataaaa acattaatat ccataaataa atcccagaaa atgaacatta
     5821 cagatgtaat gtattttctg ggatttattt gatttaaaat gtatttattt catcggtttt
     5881 tccacaaggt ggaatcaatt ggaagcgaga aaatgaaaat aatcctttgt cggtgatctt
     5941 caattcgggt atgacagata atgttaagaa agaaagtgtc aaaaaaggat caaaggtttt
     6001 agctgctcct agttgatgtg ctttagttat taattcattc aactgttcat agacgatcga
     6061 aaaaggttcc tgtgtcatga ttccgcctat aggaagagaa acacaagcta tttcctgctg
     6121 attgttgaca acggtcatcc cgccaccttt ttgaatcaaa agattagcag catacagcat
     6181 atcctcgtcg tttgtcccaa cgacaactag attatgcgag tcatgggcaa tcgttgtcgc
     6241 tatcgctcct tgtttcagct gaaatccttt cactatgcct aatccaatgt ttcccgtttg
     6301 atggtgacgc tcgatcaccg caatctttaa ttggtctttt tcgattgaag gaatgaatcg
     6361 ttcgccttgt cggtccactt tttctaccaa atctttagtc actagactat tcgggataat
     6421 ttcgatcaca tgggcttgtg aagaagaaag aagcagctct aacgaatgtg gatttaatgg
     6481 ttgagcgttt agttttggca gacaacacgt atatgaattt gaatgatcag caaataaatg
     6541 gtcttggagt tgcccagatt gaacaactaa tgttccctta tagaaaactt catgaattgg
     6601 cagcttggta agatcgtctg ttaagaagaa atcagcttga tacccagggg caatcgcacc
     6661 tagtgttttc aaatcaaaac attctgctgc attcaatgtt gccatctgaa tggcttgtaa
     6721 tggatcgatt ccaagtgcaa tagcttgacg gacgatatga tcgattgatc cttcttttac
     6781 taaatcattg atcagtttat catcggtgac aaagaagcat cttcttgaat tttcaggtgt
     6841 gatcgccggt agtagcgatg ccagatcttt tgcaacggtc ccttctcgaa ccattaaata
     6901 cataccaaga tccaaacgtt ctttagcttc ttttgcagtt gtagcttcat gatccgtccg
     6961 aatacctgct gcaggataaa catttaactc ttccatgccg ataccagctg catgcccgtc
     7021 aatttttttc ttatgctggt gcatcaattg gatcttttct aggatgtctg tttcattatt
     7081 tgctactgct tgatagttca tgacttcagc taagcctaaa acttcgggtt tttgtaaaaa
     7141 aggggctaat ttttttgcat ttaaatttgc accattggtc tcaaaagggg ttacaggtac
     7201 acaagaaggt agcataaaaa agatattcat gagtgtttgt cttgcatctt ctatcataaa
     7261 ctcaagacct gtactcccag caatgtttcc tatttcatgg ggatctgtca ctacagtagt
     7321 aactccatga agcaaggata cttttgaaaa ttcgcttggt gataaaagtg agctttcgat
     7381 atgcacatgg ccatcgatga atcctggcac tagatattgc ccattagcat tatgtacgct
     7441 ttttccttcg tattcaccga ttcctacgat cattccttcg cagattgcta catctttttc
     7501 catgatttct ttcgtaaaga cgttgacgat cttagcatgc ttgatcacta ggtcagcagg
     7561 ctttttttta cttgctactt cgatatattt ccttaatgtt gtttccaatg gagtgcctcc
     7621 caagataaat ttttataagt ataacataaa ttcggttttt gccaatattt ttttgtaaat
     7681 tcattttatt tgaaacaaaa agatcaaaaa gacgtatgtt ttttgtggag gggagaataa
     7741 tggaaataaa acgattatcg gatcaaatga taagtgaaag ttttgccaaa catgcccaag
     7801 acgtatatat attgccagct tcagaagtat tttacatcta ttttcgctat ggaaaaaaac
     7861 gaacattctg gaagaaagtc tcttcggcag atggacagca actgatctca agatttaagt
     7921 atttgggaca gatggatatc ggagaaaaaa gaaaagctca gttaggtgca tttacttatt
     7981 ctttagaaaa acaggaagtt cgtctgcggt tgtcttctgt aggagattac cttcaacgag
     8041 agagtttagt gattcggcta ttatacggta cttttgaaac accccatcgt tgctttagtt
     8101 ctcgagattt tgcaactatt ttacagaaaa ccgtcagacg tggattatac cttttcagcg
     8161 gaccagtcgg atcaggcaag acttctctaa tgtatcggtt ggctttggaa gaaaaattgc
     8221 aagtgattac tatcgaagat cctgtagaga tagaagaacc gttttttctg cagctacaga
     8281 tcaatccgaa aatagcacag acttatgata cacttttgag actcgcatta cggcatcgtc
     8341 cagacttgct aatcattggc gagataagag atgaatcaac tgcacatgct gcggtaagag
     8401 cagcactaac agggcaccgg gtttttgcaa ccgtacatgc acgcaatctt gaaggtacat
     8461 tggtcagaat ccatgaactg acaaagaaaa aagaagagct atctgaatgt ttagctggtg
     8521 tcatttatca agaacttttg gaagatgcca atcaccatcc ttctgtttta tggagttatc
     8581 aatttatgga ggaagaatca gtaaaaaaat catgggagga aagttatgaa gaagctcagg
     8641 aaaatatttg gcagtcagaa ctattctaaa ggattaacaa gaagccagca aaaccagttt
     8701 gcacaaacca tgggagaact gcttttatct ggttttagtc tgcaagaatc cctttattta
     8761 ttactcacga tccgttcgtt tccacctgtt attttggcaa atatccaaca tcagctaaag
     8821 gaagggcaag cgtttagtga ggtactttcg caaataggat atggagcaga gcaactggta
     8881 cagatcgagt tagctgaacg tcatgggaat ctgccgacaa ctttgttgga aattgccaaa
     8941 cagtttcggc ttgttgaagg atttcgcaat gatttgaaaa agctgcttgc atatccgatg
     9001 ctattgctca cctttttgct aggtatcttg tttagtatgc ggttgttcgt tttgcctcag
     9061 cttattggtt caggaatggt catgcaagag cattggggta ttcagctgat acaagtcttt
     9121 cattggtatg ttctactatt catcctagcg gttactctat tggctttact agtaaggtat
     9181 cgtctgatga agttgtctcc tgttgatcag agtgaatgga taagcagaca attattgatt
     9241 ggaccgatat attccttgta tcaatcggct tatttgtcac tagagattgg aaagcttttt
     9301 catgaaggtt tcgaattaag gcaaatcata gtctgcttaa aggaaacgaa acaagaaagt
     9361 ctgattcagc atcttgcctc taagttgatt caaggattgg aggcaggtat gtcattggct
     9421 gagcagttcc agaattatcg ttttctatca gaagaattca gtaaaattgt tttacaggga
     9481 gaggcaaagg gaagtttagg taaagaactg attttttaca gcgaatggac aagaaaacag
     9541 cttttcaaac gtcttcatca ctggatgcat tttattcagc caatcatttt tttgggcgta
     9601 gcggctttga ttttattagt ttatgccgct gttttattac ctgtttacgg aagcatagag
     9661 gaggttttgc catgaaaaag agaaaaatat cttattatag cggttttaca ttgatcgaaa
     9721 tgctaatcgt cttactgatc atcagtgtat tagtgttgtt gttcgtccct aatttgtcgc
     9781 gttataggaa tcatgtagac caagaaagtc gtgaagcgat catccagttg gtagacacac
     9841 aaaaagagct ctatgcgctt caaaataatg gaagagttcc tactgtggag gaattgttga
     9901 atgaaggcta tatcaaacga gaacatgcag aaatctatca gcggccttga aggtaaggtt
     9961 ttagcatcag gatatacgtt gtttgaatca ctcttactga ttttattact tacaacgatc
    10021 ctttcttttc cagttctcgc attttctgca tggaagaatg aattggcagt ctatcaattt
    10081 ttcggccaat ttgaaaaacg aatctattct acgcaaaaaa tcgctattgt gaatcagatc
    10141 caaacaggct tttattggaa tagtgaagag aatcaaatca tttttcatgt tccgaatcca
    10201 gataaaataa attgggaagt attagatatt cctgatgaga ttaccttgaa acgccatgct
    10261 tctattactt ttgctgctag aaccgggaat gaaagttcac taaaagctta tcaattttat
    10321 tgggaagaaa aagagcggac gattacgtat caattccaga tagggagtgg tcgctataca
    10381 aaaagaattg aataaaacag gatttgtttt gttggagtcc cttacagcgc ttatgatcgc
    10441 ttctgtctgt gtctacttag tgagctttgg ccagctgttt ttgcttcagg cagaaaagaa
    10501 aagtggggag gaactgctat ttattcgaat gatttatgaa gatatcaaga cgcagcggat
    10561 gtatcacaaa agaccagagc gaagggaaga aatgatccca tacgatatcc aaattgtcga
    10621 taataatgga gtaatcgaaa aagtgtttgt caatatggag aaagaagcga tcagtattga
    10681 aaaaacaagt aattccagca tttacgctga ttgaatgtct aattggactg atgatattga
    10741 gcagtctatt gctcacattc aatcttttga ttcagcaaac catccaagta agtgaatttt
    10801 tgcagcgtaa agatcaaaaa gagtggctaa tatttttagc acaattagaa gaagaactca
    10861 agagcagtca caatgtctct gtgaaaaatc agcaactgca ctacacgatc gaggataaac
    10921 agtatatcat cgaaagatat caggcaatga tacgtaaaag aagaacttcc ggcggacatc
    10981 aacctatgtt aacaagtatc actgagcttc aattattgga aaaagaacac acaatttctt
    11041 tttatgtaca ctttgaaaat ggagaagatg gatatgccat atggacaaaa aacgatcagt
    11101 agaaaatgtt ataagggctc tattttattt tctgtcttgc ttttatttct tttatgtacg
    11161 tttttattga tggcagcatt agaaagctac cgtttgtcaa tggatcttaa tatacgaatc
    11221 aaaaattatt atatagcaaa aataatgaag cagatggctt tatcggaaca gtctacgctt
    11281 gccgaaagtt cggaaggagt tttttactac acaactggat ctgtaacata tcagtgggta
    11341 caacagtccc tattcttaga ggtggaagtc tcaccgttta tctttcggtt cacagaagaa
    11401 gtaaaaaatg atacagatac tagtacagaa tgatggaatg ttcgtgaaaa cgccctcttt
    11461 tctgttataa cactgttttt aataaaaaaa tgtttgccgt ttcacaaata aaaaacagtg
    11521 aaaacgattg aaattttgtc aattgttcga tagaattaaa caggtgaaaa aattgttata
    11581 atatatctag aaatgaggtg caccatgtta ccagaaaaaa tggaacaagg gtttaatcaa
    11641 aacctggaag ctattcagct tttacagaat gcattgggaa cttccttttt agaagcctat
    11701 gtcgaaaatg cagaaaattt aatagatgat tatcaagtac gtgtggtgga tggagtgccg
    11761 acaaaagaga caacgcaacg gatcacagct ctttatgaag agttgaagaa actttctttc
    11821 gagccagaag aatggcgcag actgtctcaa ttacttttat tgaagggcag ccagacagaa
    11881 catttgcagg cgaaccatca actcactcct gatagtatcg gttttttatt tgtttttctt
    11941 attgaacaac tatacacaaa taaaaaagca ccggttaaga ttctggatat tgcggcagga
    12001 atgggcaact tgttattaac agttctttta aacctatcga atgcggggta ccaaacagaa
    12061 ggaattggtg tggatattga tgatacattg ttggctgtcg cagcttctac aagtgatttg
    12121 acacaagcaa atgttcaata ctttcatcaa gacgggttgc aggaattatt aatagatcct
    12181 gtcgattttg caatcagcga tttgccaatc ggttattatc cgaatgacga aaaagcaaaa
    12241 gagtttttaa caagtaccga agaaggccat agttatgcac atcatttatt gctagagcaa
    12301 tcaatgaaat atgtgaagcc ggatggtttt ggtttgtttt tgatgccgag tggattttta
    12361 gaaacggatc aaagtgaaga aatcaaaaaa tggtttaaag aagaaggtta tcttcaagga
    12421 atgattcaat tgccagatga attgttccgt aataaacaat cgcaaaaaag tattttgatc
    12481 ttacagaaaa aaggaccaca agcacaacaa gtaaaagaag tcttgcttgt gaaacttgct
    12541 tcattaaaag aaccagagaa ggtgacggaa tttttcaacg agtttaaaaa ctggaaatca
    12601 tctgctctgt aatcattcaa cgagaaggag agtcatatgt ctaaaacaat tgcaatcaat
    12661 gctgggagtt caagtttgaa atggcaatta tatcaaatgc cagaagaaac cgtagttgcg
    12721 aaagggatcg tcgaacgtat cggtttacaa gattctattt ttaccatcaa gtacggcgat
    12781 aatcaaaaat tcgaacaaat catggatatc gaaaaccacg aagtagcagt aaaaatgctg
    12841 ttagatcagt tgattgaact gcaaatttta agctcttatg atgaaatcac cggagtaggg
    12901 caccgtgttg ttcacggagg agaaacttat ggggattcag tagtgatcga tgagaaagta
    12961 atggaccgca ttgctgaatt agcagaattt gctcctttgc ataatcctgc aaacttaatg
    13021 gggatcaaag cgtttaaaaa gattttacct gacattttga gtgtggctgt attcgataca
    13081 tctttccact caacaatgcc aaagcaaaat tatttatata gcttaccggt gtcttattat
    13141 gaagatttca aagtaagaaa atatggcttc catggcacaa gtcatcgtta tgtgtcggaa
    13201 cgtgcggcaa aattattgaa caaaccgatc gaagaactaa aaatcatcac ttgccactta
    13261 ggaaatggtg tatcgatcac agcagtcgat ggaggtaaat ccatggatac ttctatggga
    13321 ttcacaccat tagctggggt gacaatgggt acacgttcag gtgatatcga tccagctgtt
    13381 ctcccatatt taatggaaaa attagagatt gatattgatg aaatgatcaa tgttttgaac
    13441 aagaaatctg gtctgctagg cctaacagga ttgtctagtg atatgcgtga tcttgaaaag
    13501 aactatgaaa aagaacatat tcgtttagct tatgacattt tcgtggaccg catccgaaaa
    13561 tacatcggcg gttatgtgac aacgatgaat ggtgttgatg caattgtctt tactgctggt
    13621 atcggcgaga atgacggaca tgtacgtagt gaaatcatca aaggtatgtc ttggtttggt
    13681 tgtgaaatcg atccagcgtt gaatgaattg cgtggtgaag aagtagatat ctctacaaaa
    13741 gaatcaaaag taagagtatt agtgatccca acagatgagg aactaatgat tgcccgtgat
    13801 gtggagcgtc tgcgcggcta agccaaagca ttcgttagga taaaagatga aacgcatgca
    13861 agagggaatt cttgcatgtg ttttttttgc ggagaagacc gcaaaatggt aatttaactt
    13921 caatttccct tcttttttac aggatcttct tagggaattt tgcttggaaa agtggtcaaa
    13981 agggaaaaga ctggcatttt atttattgat tttcaggaaa atcccaatat tttattttca
    14041 ttcatcttta taagggacat tacatatgta aaaagaaaaa acatttttag atcagcctcg
    14101 tgggctgtcg actttattct tcgctttatg tttagctaga aaaccgatcc gaaacattca
    14161 ttgatcgaat aataaaaact tgattttcca cctgtacttt gcctgaatcg tgaaagcaca
    14221 ggtatgaaaa tcaagttttt tgttgcgaaa aaacgtccta gtcaatcagt tggccgagcg
    14281 gctggcggct gatctgctcc tgatcaataa cgagtgcttc ttggaagtgt tgctgcaaaa
    14341 agtagcggtc atggctgact gctaggagcg ttccttgata gtcttgcagc atttcttcaa
    14401 tttcttctcg agcatagctg tcgaggtgat tggttggttc atccaaaatc aggacgttga
    14461 ttttttctaa aaagagtttc agcaacgcca aacggatttt ttcaccaccg gataaatctt
    14521 tgatccgttt acccacatcg ctttgataaa agccactttt ggctaattgc cgtcgagcga
    14581 cttcttcgtt tccagtcaat gtgatggcgt aagccagcaa acggctatcg ggatcggcaa
    14641 actgcagctg ctgcggcaaa taaccgattt gcaagctact acctaatttg atggtgccac
    14701 cgtaaggctt ttcctcaccg agtaataatt tgagtaaggt tgattttcct gcaccattgt
    14761 cgccgatgat ggctaaatga tctccacgat agactgcaaa actgctgtct ttgaatagta
    14821 cttgatcagc gtactgctgg tgcaagtttt gaatgatgaa aacttctttg ccagattttc
    14881 caccattaga caagctttgc agccgatttt tcgggggagg tggcggtttg acgagtgtca
    14941 gtttcgccag gcggcgttcc agttctttgg cttttttgaa gaaggactca ttgtctcctt
    15001 catgtgccca ctgacgaaaa cgacgaatca tgactttcaa ccgctggact tctttttgct
    15061 gcagttcgta attttttgtc agctcagcca agcgagcttc tttcaagact cgaaaacggc
    15121 tgtagtttcc gggatactca atcaatgcac cttcttccag ttcccatgtt tttgtggtga
    15181 cttgatcgag aaattgccga tcatgagaaa cgaccagaac cgattttttt gtattctgta
    15241 aatagttttc caaccagcga atactgttaa gatctaaatg attggtcggt tcatcgagta
    15301 aaagtaaatc ggcatcggct gctaaaattt tggctaaagc gactttaact cgttcgcctc
    15361 cgctaagttc tgttaaccgt gcttcctgac ggtgtggaat ccctaagcct tgcaagatcg
    15421 ctgcaatccg gtcttctaat acgtaaccgc ctagttcttc aaagcgatgc tgcagctcac
    15481 cgtaacgggc cagacacttc tctaagtttg tatctggttc tgtcatcaat gcttcgtagc
    15541 gactcatttg ctgtttgagg tcctgtatct cagcggcaga atggagcaag tagtggttga
    15601 cggtcgcttc ggaaactgta agttcttgtt cgaccgtccc gatctttaag ccttttttgc
    15661 gactgataac accgctgtcg acaccttctc tgccggtcaa gatttgtaaa aaggttgatt
    15721 tgccagttcc gttgataccg actaaggcaa ttttttcacc agcttcaatt tgacaggata
    15781 aatcctcaaa taatggattc ccgccgattg tttttttaat agaaattgct tgtatgatca
    15841 tgatctctct ccttgagacc actcaaaaag gccatggtta tccatggcct gtgttattta
    15901 aactcagatt atcatgagaa aaataccttg agatggccat tgattttacg tgaattcaac
    15961 tgttttggac aaacttgtcc cgtcaacagc aactgtaaaa ccaattgcat ggctaaatgc
    16021 gatatggtat cgttggtaat tttcattact tgttatttta gtcatgcgca tcatagtatt
    16081 ttccctcctt cgtgtagttg tcttttccag tgtacctgaa agtgtcagaa agttcaacta
    16141 gcgctgacat ttacttaata tttatcgatg tgtaattctg tcagagagct ttttttatct
    16201 gactgagggt aatgtctcgt ggaccacatc attgtattct gagctaaacc agcgttcagg
    16261 cgaaatcata tggtgtttga taaaaaactt tgtctacatg acttcctttt gccatttgct
    16321 taataccgtt gcattaaaca gctcttctct ttggaaatct caccaacatc gcgttcagga
    16381 gtatcgttgt ggttgcaatg gcaagcggta gcctttcatc aattcttgaa tgatttaccg
    16441 aatgtagcac ttgccttctc gcggtacccg aacccgaaat aaaattttag tttggcgata
    16501 aaatcggtat ccgccatcga tacttcatat tttttcgtat cagattcatc ggaaacttcc
    16561 acattgacga accaataagc tttggcatgc ttaggtcgtt ttaaaccaca ccagggcgac
    16621 taatcgccct ggtgttcact tttttttatt ttacttgaac tcattgactg ttttcccttt
    16681 attttaaaca ttataaagac cgatgagtgc ttgccgcgtc ttttgttttt atcacggttt
    16741 tttgtgcaaa aaaacctgcc gatagttggc aggtcgtcta cgtgttaagc tttggtgtgg
    16801 tctttagctg gcaattggtt ttctaaatca gttcggacaa caagcacatc gcaagctgcg
    16861 tttctaataa catattcaga aacagaacca ataaataaac gttctacagc attcaatcct
    16921 gtggctccta acataatcaa atctacttga ttatcttctg ggatttctct ggcaataatt
    16981 tgttttggtg agccatattc tacgacagag gttacattat tcaagccagc tttcttcgca
    17041 ttgctttcat aatctgccaa tgtttgcttt gccatttcag tagcttgttc tgcaagcatt
    17101 ccatcaaagg atgaaacggt ttggaaagaa cgtgtgtcaa tgacatgtgc taatagaagt
    17161 tctccgttat ttcggatagc tacattgacc gcctttttaa aagctaattc agcttcatca
    17221 gaaccatcta cggcaaccat gatttttttg tattgttgta acataagcat tcactcctca
    17281 agtcaatcgt attgtactct tttattgtag aacactttag ggaaaaagag aattatttac
    17341 tgctttggtt cagcaatttt ttttgcaaat cggatactga aggtggcaga aacaataatt
    17401 acgatcagta aaaagaccaa ggcaataaag cgttgattga aaaaagctgt taaaataccc
    17461 attacgccta aaacagcata tgcagctccg taaaattgta ggaatccttg atttttatca
    17521 tttttgttga tcaatacaaa aaagatatcc tgtttattaa ataaataata gctaacgaat
    17581 aataatacta aagtggcgat aatcattaaa atcctaatca tgaacaaatc ctccaaaata
    17641 agcaacaaat agaaaaagca atttgccaag agcaaattgc tttattcttt aaaagatggt
    17701 aatctccgtt aatgccgttg tttgtcctgt agtattgatc ccgcgaattc aagcaggtgg
    17761 gtcccatggt cgtagcttcg aactaccaaa tgataaggca tgttaccagc agtgacacaa
    17821 gacgggtccc aagatatcaa taaaaatgtt cggtcaacac acaaagagga caattcgaac
    17881 atcacagatt tcccacctct atagtagcat atgaatttaa aaagagcaat gagagagctc
    17941 gcagaaacag aaccgttttc ttgtctagtt ttttggagga tgctttttcc actcttttat
    18001 acggtaatac tgttgaccca gagcctgttc atatttccct gtatcttttg gctgataata
    18061 ctgagcattc ttcagtttat ctggtaaata ttgctgattg acccaagcct gatcaaaatg
    18121 atgaggatac tgataaccca cgccacggtt gagtgatttc gcacctttgt aatggctatc
    18181 tctcaaatga tcaggaacat ctccagcttt gccctctcga atatcagcaa gtgctgcatc
    18241 taatgccatg taggcagaat tggattttgg cgacaagcaa agatcgacga cgacgtctgc
    18301 tagtgggata cgtgcctcag gcaatcccaa tttttcagca gctaatacag cgttcactgt
    18361 acgagccgca gcagcaggat tacctaaacc tatatcttca taaccgataa ccatcagacg
    18421 ccggcaaata cttgccagat cacctgcctc aactaaacgg gcgagataat gaagtgcagc
    18481 atccacatca cttccacgaa tcgatttttg aaaagccgaa ataacgtcat aatgagcatc
    18541 tccatttttg tcatgggtaa gagcttttct ttggacacat tcttcaatga tcgacagtgt
    18601 aagatgaatc cttccttctt tatctgaagg agtcgatagt gtagccagtt ccagcccatt
    18661 caatgcactc cgcaaatcgc cgttcgttgc acgcgaaagg tgaagaagag catcttcgtc
    18721 taactggatt gcttgttgtc caaggccgcg ttctttatcc cttaaagcat gttcgactgc
    18781 caactggatg tcttgttctg ttaatggttt gacttcaaag atctgtgtac ggctgcggat
    18841 cgctggattg atggtaatat aaggattctc agtagtcgct ccgatcaaga tgattcggcc
    18901 actttctaaa tgaggaagca gaaaatcctg ttttgtttta tctaatcggt gtacttcatc
    18961 caataagagg atcactgtac cactcatttt tgcttcttcc gctacaactt gtagatcctt
    19021 ttttgaatct gtagcggcgt ttagcatgcg aaatgcataa ttagtagagc cggcgatcgc
    19081 acttgcgata ctcgtttttc cagtaccagg aggtccatat agaatcatgg aagagagcat
    19141 gcgagcatcg accatgcggc gtatgatttt tccttccccg actagatgct gctgaccaac
    19201 gacttcatcg atcgttcgag gtctcatgcg ataagccaat ggctgttgca taggattttc
    19261 ctccttcttg tttttacgtc ccttaattat atcatattta gcaagatgcc tagaaagaac
    19321 agccttctgt tgttttgttt tcatagctta tccaactaat attgtgtatg ataaagtagg
    19381 tgagaaaaat gacggataaa caaaagatag atgaattttt ttggaataaa acgacgccag
    19441 aagtggcacg ggatttattg gggatgtatt tggagcatga cacaccagaa ggaagattag
    19501 ctggatatat tgtagacgcg gaagcatacc taggtccaga agacgaggcc gcccatagct
    19561 atggtttaag aagaacaccg cgtgtgcggg caatgtatga aaaaccaggt acgatctacc
    19621 tttacacgat gcatactcat cggattttga acatcattac tcagccagaa gggattcctc
    19681 aaggagtaat gatacgtgca atcgaacccg ccgcaatgat tgatcaaatg agtaaaaatc
    19741 gtggcggaaa aactggtcca gatatcagca acggtccggg aaaattagtg gaagcattag
    19801 caattcctca agaactttat ggtcagtcta tagcagatag ttcgttacgc ttagtttttg
    19861 agaaaaaaaa gacaccaaaa aagatcaatg ctttgcctag aatcggtatc ccaaacaaag
    19921 gtgtatggac agaaaagccg ttgcgttttg ttgtgtcggg aaatccttat atctctttac
    19981 aaagaaaaaa ccaaatcgag aaagattggg gttggaggaa agaaaatgaa aaagaaggat
    20041 ctattaacat atttagatga aataattgaa aaacaagtga cagactatga tgtagcttta
    20101 gattgggata caaaaaatca tacgatcgag atcgttgttc gcttgtttgc agaaaataaa
    20161 gcacaatttg agattgatga tgcagaaggg atcgtttcgc aagaaccaat tatcgaattt
    20221 gaagacggcg tacttctttt taatcctcag aaatctgttt ttgatgaacg caattatcta
    20281 gcagtaatcc cttatgaagg aaaaaaaggg ttggcaaaat cagtagctga ttctttagtg
    20341 gaatatctaa atgaagtatt agctcaaggg caaagcgatt tgcttgattt tttggatgaa
    20401 gacgatgacg aagctgtatt cgagcttcac tgggataatc agcaactagc agaattagta
    20461 gaagtaaaac agcaaaatga agcagatact tatttaccgt acccaagtta ttaaggagtg
    20521 acagatatga aatggaatga agtaaaagta gaaactgaaa gtgaagcagt cgaagcagtt
    20581 gctaatattt tgatggaggc aggggcgagt ggtgtcgcga ttgaagattc tttagatgtt
    20641 gaacattttc agtcggatca atatggtgag attttagata aaaatgattt tacatcgctg
    20701 aaagaaggcg cactagtcat ggcttatttt ccggaaacga ctttcttacc ggaaatcttg
    20761 ccttttatca aagatcgtat cacacaatta cctgagtttg gtctagctat tggaaaaaat
    20821 aaagtaacag ttagtgaagt agaggaaagc aactgggcaa cagcctggaa gaaatactat
    20881 catccggtgc gtattacgcg aatgctgacg gttgcgccaa gctgggaaaa ctaccagaca
    20941 gaagatcctc tagaaaaaat tatcacacta gatcctggta tggcatttgg cacaggcact
    21001 catcccacga cttccttgac attgacagca ctagaaacag tcttgcgtgg tggtgaaaca
    21061 ttgctagatg tgggaactgg gtcgggcgtg ctaagtattg cagcaaaata tcttggtgca
    21121 aaagatgtct atgcctttga tttagacgaa gtagccgttc gttcggcgaa agaaaatatg
    21181 gatatgaatg aaatagccaa agatgtccat gtatcagcta acgatctttt gacaggaatc
    21241 gagattgaaa gtgatgtaat cgttgcgaac attttagcag atatcatctt attgatgatc
    21301 ccagatgctt ggcgtttact gaagcaaaca ggcacgctga tcgtttcagg aatcattgaa
    21361 gagaagaagc aaatggttct ggatgccatg ttagaacaag ggtttatcgt ggatcaaatt
    21421 ttccagcaaa aagactggta tgcaattatt ttgaaaaaac cagaggtgga atagatgcag
    21481 cggtattttt taaaagaatc atatgaatca aaagactatt ttgttttaga aggggaaaac
    21541 tatcaccaca ttgtacgggt tatgaggatg gaacccgagg atgaagtttt tttggcattc
    21601 aatgatcaaa tagccattgt tgcagaaatc acggagatta ctgaagaggc tgtttatctg
    21661 aaagaaatta aaaaagaaga aaatcaaaag gaactgccaa gttcgattac catagcgagt
    21721 ggctatccta aaggggaaaa gctggattgg atcgttcaga aatccactga attaggagcg
    21781 caagcttttc ttggtttccc ggcatcagcc tctgtcgtta aatgggatgc aaaaaaacgt
    21841 atgaaacgac aacaacggct tgaaaagatt gctcaagagg cagcggaaca atcccatcgg
    21901 cagatcgtgc catcagtaga gttattggaa acgaaacaag atttatttga gcggctagat
    21961 gattatgacg tggtcttggt tgcttatgag gaatcagcaa agcaaggcga aaaatcaaat
    22021 gcagccaaaa ttcttagtga aacaaaacca gatagtcgaa tcttagctgt ctttggacca
    22081 gaaggtggat tatcccgcga tgaagtcgat tattttgtag aacacaaagg gatactttgt
    22141 ggattaggac caagaatcct tcgtacagaa acagcacctc tttatttatt aagtgctgct
    22201 agctatcaat gggaattaat gaatccttct ttcagctaac gttcttcatt aataaaagag
    22261 tatcgacaga aagaattgaa aaaatagtca acaatttgta taatagaaac aattatttat
    22321 acaatggata cgaaaaatcg tttgaaaaag cttttaaaaa gcgaacattt ccgtaaaaaa
    22381 acgtataact gcacggattt tgggacaatt atcaaacaga tatttgtccc gattcccgtt
    22441 ttaccgaaaa aagaaagggg gatcgattcc tgtgacaaaa gaagaaattt taacgggacc
    22501 cggtgtcata aagctcgtta gtcaatacat gggtcccgaa catgtagcat ttgttgagaa
    22561 agcatgcgaa tacgcgactg ctgcacatga cggacagttt agaaaatcag gcgaacccta
    22621 cattattcat cctatccaag tcgcaggtat attagcagat ttaaaaatgg atccccatac
    22681 agtggctaca ggcttcttac atgatgttgt tgaagataca gaaatcactt tagaagatct
    22741 gagagaagaa tttggcgatg acgttgctat gttagtggac ggcgtaacca aattagggaa
    22801 aataaaatat aaatcccacg aagagcagct agcagaaaac caccgaaaga tgctgctagc
    22861 aatggctcaa gatttacgag ttatcatggt caaattagct gatagactac ataacatgcg
    22921 tacgttgaag cacctgcgag aagataagca aagaaggatc gctcaggaaa ctttagaaat
    22981 ctatgcgcct cttgcacatc gtctagggat cagccggatc aaatgggaat tagaagatac
    23041 agcacttcgt tatctaaatc caaaacagta ttaccgtatc gtccacttga tgcagacgaa
    23101 gagagaagaa cgtgaaaaat acgtaagtgg tactgttgaa gatattcgaa tagcgacaga
    23161 agagctgggg atttttgcag aaatctatgg acggccaaaa cacatttatt caatctatcg
    23221 taaaatgaaa gatcagaaaa agcagttcaa cgaaatttat gacttgctag ctattcgagt
    23281 gatcgtagat tcaatcaagg attgttatgc tgtattagga gcaatccaca caaaatggaa
    23341 accaatgccc ggcagattta aggattatat tgccatgcca aaagctaata tgtaccaatc
    23401 tttgcatact accgtgatcg gtccggcagg aaatccggta gaaattcaaa tccgaacaca
    23461 ggaaatgcat gaaatcgctg aattcggggt tgctgcacac tgggcctata aagaaggaaa
    23521 aaatgaaaaa gtagaaccag atggtatgac gaaacaatta agctggttcc atgagatact
    23581 cgaacttcaa gacgaaagct atgatgcttc tgaatttatg gaaggcgtaa aaggagatat
    23641 ctttagtgat aaagtctacg tcttcacacc aaaaggagac gttactgagt taccaaaagg
    23701 atccggacca ttggactttg catacagtat ccatacagat atcggtaaca aaaccactgg
    23761 tgcaaaagta aatggcaaaa tggtgcagct tgattacaaa ttgaaaaacg gagatatcat
    23821 tgagatcatg acttctccaa attcatttgg cccaagtcgc gactggttga aattagttgc
    23881 tactagcaaa gcaagaaata agatcaaacg tttcttcaaa gcccaagatc gagaagaaaa
    23941 tgtgatcaaa ggccacgaat ccgtggtcaa atgtattaca gatctaggat ttacgcctaa
    24001 agatattttg acgaagaaca aactgcaaga agcactcgat cgttttaatt atcaaacaga
    24061 agatgatctc tatgcagctg tagggtatgg agaagttagc cccttgacga tggccaatcg
    24121 tctgactgaa aaagaacgta aagaacaaaa aatcgagcag caaaagcaag aagcagaaga
    24181 aatcatgaat cagccgaaaa aagaacctga caaaatgaaa gtacgtcatg aaggtggcgt
    24241 tgtcattcaa ggggtagaaa acttactaat tcgtatcagt cgctgctgta atccgattcc
    24301 tggtgatgat atcgttggtt atatcactaa aggcagaggg atatccattc atcgtcgaga
    24361 ttgtccgaat gttcagcctg acaaaccaaa tgtagcagaa cgtttgattg aagtcgaatg
    24421 ggaagataca tcgaatacac gaaaagagta tgatgcagat ttggaaattt acggctataa
    24481 tcgttcaggc ttattgaatg atgtacttca aacagtcaat gcgctaacga aaaatctcaa
    24541 cagcgttgaa gcacggacga ataaagataa aatggcgacg atccatttga cggttggtat
    24601 ccagaattta tcccacctaa agagtatcgt ggataaaatc aaagcagtac ctgatgtcta
    24661 cagtgtacgc cggacgaatg gataggagga cagatatgag agcagttgtt caacgggtaa
    24721 gtaaagctgc tgtgtcagtc gatcagcaag aaattggaaa aattggctac ggcctacttg
    24781 ttttattagg cattcatgaa accgatacgc aaaaagatgt ggactatctg gtaaaaaaaa
    24841 ttgcacaaat gcgtattttt gaagatgaac aaggaaaaat gaatattagt gtagaagatg
    24901 tgggaggaca aattttaagt atctctcaat tcacactgtt tgcggatacg aaaaaaggaa
    24961 atcgaccaag ctttgtggaa gccgcacgac cagaaacagc tattccttta tacgaatcat
    25021 tcaatgaagg aatcagaagt cgcggcatca cagtcgctac cggacaattc ggagcagata
    25081 tgtcggtttc tctcgtcaat gatggacctg taacgatcat tattgattct aaaaacaaat
    25141 aaagtaatct ggttttcact agtaaaaact atgaaacacg tcgcttaagt tagactgata
    25201 aactctaact taagtggctt ttttgtctgc aaaaagcgct tcttttgtca gcagtcggaa
    25261 aaaaagttaa gcttaaatta tacaagttat tttttatagg aggttgctga agatgaaaga
    25321 agtaccagta gtagatatca aaatcacaga tttaaaaaaa ttgtatcaaa aaggatacaa
    25381 catgttggag gagttacgcc atgaagcgga cgctcccgtc gtcaaagcaa agattttcaa
    25441 taaagaagct atcacgatct acggatcatc agcagcaaaa gtattttatg atccaaggaa
    25501 tttcaaacga aaaggtgcta tgccaaaatt agtattgaag acactttttg gtcaaggtgg
    25561 agtacagact ttggatggag ctgctcatca ccatcggaaa aatattttta tggatctaat
    25621 gacaccggaa agaatggaag attatcatcg tatcttagat aagaatctga cacaagcact
    25681 tgaagcacag catggtcaat ttgaactatt tgatttaagt aagatggttt tctttacatc
    25741 tatttgcgag tgggcaggta tcaatttatc agcgatttct aaagatgagg tcgaaaaatt
    25801 agcagaatat caaatctcta tgatcagcgg aacgtttact tctccgattg atcacataaa
    25861 aggtgtcgaa aatcgcaaaa aatcagaaaa atgggcgcaa ggcttgattg aagaagctcg
    25921 acaaaatcct gtggctggaa aagaaaatgt ggcattatat gcttttgcca atgccacaga
    25981 tttagatggt cagcttttac ctctggaagt ggcagctgtt gaattattga acatcatccg
    26041 tccaacggtt gctctaactg tgtgggcggc attgatggga catgcacttt tcagtagacc
    26101 agatttgtat cagcaattaa aaaatgactt ttcgacgtta caagatccgt ttattcaaga
    26161 aatgagacgc tattatcctt tcttcccaat gctacctgcg atttcgctga aagaagtaga
    26221 agtagatggt tatcgtatac cagaaggcag ttgggttatt ttagatttat atggaacaga
    26281 ccatgatgaa cgaacagttg aagcgccaga ttcctttatg atcaaacggt atgtagggaa
    26341 agcaaaagat atttcctata aagaagaata tgagatgatt gcacaaggcg ggggaaattt
    26401 tcgacaaatg catcgctgtg caggagaatg gatcactctt catagtctac gtgtgttttc
    26461 cgatcagcta gtaaataagt ttgagttctc tgtacctgaa caagattgga cgattccatt
    26521 caatcagttt ccgacttatc cgaatagccg agcgctactt tacaagaatt agattagcat
    26581 aaacttatcg aaaaaaagga agatcaaaca gtgctgatct tccttttttc atattactat
    26641 aaattgataa ggtcaattga tcaaaatcca cgaaatgctt catcaatggt ttgataatct
    26701 tcattggata aatgcaaatc taaagcttgg acattgtcag atacttgctc tggacgctta
    26761 gctccaggta taactacaga cactcgtgga ttcttcatgt accaagctaa aacaagttgc
    26821 gcaggagtgg cttggtatct tttagcaatg gggcgaagta catcgacagc ggttaaaatt
    26881 tctctgaaac gttctccttg gaaatctgga tttctttttc gaggatctcc ttcaccaaat
    26941 tgtttttcct caccaagttc atattttcct gtcagcaaac cggaagcaag aggaaaatag
    27001 ggaacaaaac tgattttgtt tttttcaaga taagggaata attctttttc agcctgccga
    27061 tggatcaaac tgtatttatc ttctactaca tcgacatatc catctgcatt cgcttctttc
    27121 aattgttcta acgtgaagtt tgacacaccg actgctcgga tttttcctgc ttcttttaat
    27181 tcgtgcaatg tagcaactga ttcatttttt ggtgtgcttt catccggaaa gtggatataa
    27241 aaaatgtcga tgtaatcagt ttgcagacgt tttagtgcat cttccaccga ttgtttgaga
    27301 aactcaggag aattatcaaa tgttcgccct ttatttggta catgagcagc ttttgtagcg
    27361 atgacgacac gtgagcgatc atattctttt tccttcagta cctcgccaat cagttcttcg
    27421 gaacggctgt ttccgtaagc ataagcggta tcgatcaaat tgatcccgct attcaaagct
    27481 gtacgaacta cttgttttcc tgtctcatct tccaaaccgt caaaaagatt atgtcctcca
    27541 acggcatttg ctcctaatcc aagctgttct gcgtagactt gtgaatgtcc gattcttatt
    27601 tctgccatag ctgattcctc ctttttgtct agtctaaaac aaaataccaa aaagctgaac
    27661 taaaacgttt ttgtgagggg aaatagtcag atatctcttg actttgagac tggtttttag
    27721 taggttataa gtaatatcga atgtcaatga aagagcgagt aagtttttga aactttacaa
    27781 gagaggatca tcgaggctga aaatgatcta aagtttcatt agcctaaaga cactctggag
    27841 atggacgagt gaaaagccgt cccgcgtacg agcgttattc gtaagaggaa agagaaatct
    27901 ttcaaaatta ggtggtaccg tgtatgaatt tcattcaccc ttgttcatga tgaacaaggg
    27961 tgattttttt atttacatag ctaagaaagg gagagaaaac tatgagtttc caaagaccaa
    28021 aaggaacaaa tgatattttg ccaggcgaat cagaaaaatg gcagtttgtc gaagaaacag
    28081 cacgtttatt attcagagat tatcagtata atgaaatgcg tacaccgatt tttgaacact
    28141 atgaagtgat atcccgaagt gtaggggata caacggatat cgtttcaaaa gagatgtatg
    28201 atttttatga caaaggggaa cgccatgtga cgcttcgacc agaaggtaca gcaccaatcg
    28261 ttcgttcttt tgttgagcat aaattgttcg gcccagagta tgcgaaaccg ttcaaaactt
    28321 tttatatggg accaatgttt cgctacgaac gccctcaaaa aggacggtta cgtcaattcc
    28381 atcaaatcgg agtagaagca tttggatcag aaaaccctgc aactgatgtg gagagcatgg
    28441 tgatggcact tgatttcttc aaacagttgg ggatcacgca aatccggcta gtcatcaatt
    28501 cattaggtga taaagaaacg cgtcaagcct atcgtcaagc attgatcgac tatcttttac
    28561 cttttgaatc agagctgagt gaagactcta aacgccgcct tcatgaaaat ccattacgcg
    28621 tattggacag taaagacaaa cgagatcaaa aatttgtggc agaagctcca tctatcttag
    28681 attatctaag cgagcctgct caaaaacatt ttgataccgt tgtttccatg ctggatgcat
    28741 tggctgttcc ttatgaaatc gacagtaata tggttcgcgg actagattat tacacacata
    28801 cgatttttga aatcatgagt gacgcaccaa aaatgggggc acaagcaacg atttgcgcag
    28861 gcggacgtta tgacaatcta gtggaagaac taggtggtcc ttcaacacct ggcttcggat
    28921 ttgcaatggg tatcgagcga ttactcttga ctatggaggc agaggaagta gttatccctg
    28981 catttaatga gttggatgct tacgtggtcg cactcggaga cgaaacaaat atcgaagcat
    29041 tgaaagtggt ccaagcgatt cgaaactttg gtttttcagc tgaccgcgac ttcatgaacc
    29101 gtaaagcaaa agcgcaattt aagacagcag ataaagcgaa tgccaaatta gtattggtga
    29161 tcggtgaaga tgagcttgct agtcaaacga ttaatgtcaa agcaatggca agccgaaaag
    29221 aaaaaagttt tccattagaa gagatatatg aacattttga tgaagtctat gatgaaatga
    29281 ctttattcga gtaggaggaa aaaaataaat ggcacaaaga acgatctatt gcggattagt
    29341 ttccgaacaa caattagaac aaacagttac attaaaagga tgggtacaaa aaagacgaga
    29401 ccttggggga gtaatcttta tcgacctacg tgatcgtgaa ggaatcgttc aaatcgtctt
    29461 taatcctgaa atcaacaaag aagcatggga aatcgcggat aaatgtcgca gtgaatacgt
    29521 gatcgaagtg actggggaag ttagaagacg cggagaaaat gcagtaaatc ctaaaatggc
    29581 cactggtgaa ttcgaagtga ttgcaagtga aatcgtgatt ttgaatcaag caaaaacccc
    29641 gccatttcaa attgaagatg atcaagcaat cagtgacgaa atacgtttga aatatcgtta
    29701 tttggatctg cgtcgtccaa aaatgactaa aaacatcaaa ttaagaaatg cgacaacaaa
    29761 agcgattcgt cattatttag atgataatga ctttctcgat atcgaaacac cttacctagg
    29821 gaaatctaca ccagaaggcg caagagacta cctagttcct tcacgtgtcc atgctggaca
    29881 tttctatgcg ttgccgcaat ctcctcaatt gtttaaacaa ttgctgatga atgctggatt
    29941 cgaccgttat tatcaaatcg ttcgttgttt ccgcgatgaa gatttacgtg gagaccgtca
    30001 gcctgaattt acgcaagtag atattgaaac aacgttctta acagcagaag aaatccaaac
    30061 ttacacagag ggattgattg cgaaggtaat gaaagaagtt cgcggtatcg aagtcacatt
    30121 gccatttcct cgtatgacct atgatgaagc aatggctcgc tacggcagcg acaaaccgga
    30181 tacacgtttt gatatggaat tgatcgatct aagcgataca gtcaaagaag tagaattcaa
    30241 agtcttccaa atggctcttg aaaacggcgg tgtcgtgaaa gcattgaatg ctaaaggcgc
    30301 tgcagatcgc tactcacgaa aagacatgga tcagttaggt caatatgtag gacaattcgg
    30361 agctaagggg cttgcatggc tgaaagtaga agaagacgga ttgaaaggtc caattgctaa
    30421 attcatggga gaagcaacag aagcaatcat taaagcaaca gatgcaaaac caggtgactt
    30481 gctgatgttt ggcgcagata aaagtgaaat cgtcgctgct gcattaggtg ctatccggac
    30541 acgtttagga aaagaattag gactaattga tgaatcgaaa ttcaatttct tatgggtaac
    30601 tgattggcca caatttgaat tttcagaaga agaaggtcga tatgtctctg ctcaccatcc
    30661 attcacgatg ccaaaagaag aagatatccc gttattggct gaagaccctg caaaagtcta
    30721 tgcagaagct tatgatatcg tcttgaacgg ttatgaacta ggcggaggtt ctatccgtat
    30781 tcatactcgt gagcttcaag aaaaagtact agaaactcta ggctttacaa aagaacaaat
    30841 ggaagaacaa tttggtttct tgttaacagc tttagattac ggattccctc cacatggcgg
    30901 tattgcatta ggattggacc gttttgcaat gttattagcc ggagaagata atattcgtga
    30961 agtcattgcc tttcctaaaa acggaaaagc agcagatgtg atgagtgatg caccaagtat
    31021 ggtttcgcct ttacaattgt tcgaattgaa tattgatgta acgaatatag aagaatagcc
    31081 gataaaaagg taaaaaggat ttgtcgaata cgcttctttt gacaaccttg atttaattga
    31141 aaaacacttt ataatgaagc cataacatat aaagcggggc ttttccatga aaaaaacatt
    31201 cgaaaattgg gcttatcatg attacacgac caagctttcg gtatctatcg tttatgcgtt
    31261 gatcgcatca gtcgcattga atttctttta tcagccagga catatttatt caagtggtat
    31321 tactggtcta gctcagattt tgacgacttt gtcaaaatca ctgataggat tcgaagtacc
    31381 ggtatcaaca actttgtatt tactgaatat acctttgttt gtattggcgt ggttaaaaat
    31441 cgggaagaag tttacaattt tcacttttat cacagtcact ttgacctccc tttgtatcca
    31501 tattttaccg gaaacagtcc tatctaccga tccaatcatc tgtgcgttgt ttgggggggc
    31561 tgtgatggga ctaggtattg ggctagcgtt gagaaacggc ctatcatcgg gcggtctaga
    31621 tatcgtgagt atcacgattc gtaaaaaaac aggaaagtcg attggttcta tttcgatcta
    31681 cttcaatgca ttgatcgttt ttgttgccgg aattctattt ggctggcaat atatgtttta
    31741 cagtacgttg tctattttcg tcagtggaaa agtaactgat gtcgtttata ctaaacaaaa
    31801 gaagatgcag gtaatgatcg taacgaaaca tccagaaaaa gtagtaaatg aaatccaaaa
    31861 ctgtatgcgt agagggatca cgatcatcaa tgaagcagaa ggtgcttata agcatgataa
    31921 gcagacagta ttgatgacga tcgttacacg atacgaactg cctctactta gagaagcaat
    31981 gaaagcttct gatccacaag cttttgtaag tattgcagaa aacgtccaga tacttggtcg
    32041 tttctatgag gatggcattt agatcgagtt tgacaaaaat tcatgaaata ctgctgtaga
    32101 cagacgttcg tttgtctgca gtttttttct accatagtag aatcagcaaa gaaaaactgc
    32161 ttttttattt gaaattttct taaagttgaa aaaaagcatg tttatttttt taaatttatg
    32221 ggatgataga aaaaaatagt agagaaagga cacgattcta cttgctattt tcacttaata
    32281 cccgtatatt acgaatgaaa aaagtttatg aaaagttgga atattgaatg gaaaaacaaa
    32341 aaaggttaaa aaacagccgc tacatcactg ggtttgatgg gctccgttca ttagctgtgg
    32401 tgggtgttat cttctatcac cttctgccaa ctagtatgaa aggcggctat ttgggcgttc
    32461 cgattttttt cgtcgtatct ggttatttga tcacggatct gctgcggcag gaatgggaac
    32521 aaaatggaaa aatcaatatt tggcaatttt atgtcagaag aatgaagaga ctctatccgg
    32581 cacttgtttt tatgcttgtg acagcttcgg cttatatcac tttgtttcag cgagggctgt
    32641 taaacaatct tcgaggagtt gtggtcagca gcttactgta tgtcaacaac tggtggcaaa
    32701 tcaataacgg tttatcttat ttcgatcgat ttgctaatga gtcaccgttt acgcatatct
    32761 ggtctttagc agtagaaggt caaaactatt tggtttggcc gatcttgttt gtattgttga
    32821 tggtatttgt tcgtaaaaga aaatggatct tttatactgt gttaggtaca tccttcctct
    32881 ccgccatctt gatgatgatc ttgtatacac caggaggcga tccaacccgt gtttattacg
    32941 gtaccgacac tcgtctgttt tctatatggt tgggaagtgc gcttgcgttt gtttggccaa
    33001 gtacgcgttt aaagaaaaac atcccgaaac aagcgaaaaa tattctgaat atcgctggag
    33061 gaatctcgct tttggcactg attctttgct tcttcttttt agatgatcat tacaatttca
    33121 tctattacgg aggaatgctc ctagtgagtc tgttatgcgt agtgctagtt gcagtgacag
    33181 cacaccccgg agcaagtttg aatcgatggc tgacaaatcc agtatttact tggattggca
    33241 aacgaagcta tggcatttat ctgtatcagt ttccagttat gattttttat gaagcaaagg
    33301 tgactgatat tgccgatcat gttttgttgc atactttagt ggaaatcaca ttgattctaa
    33361 tcatcagtga actttcttat cgatatgtgg agcgtccgct agcacgtttt gattatggtc
    33421 gtacattcca agtgatgaaa ggatggttca gcaaaccgat catcagtaag agcaaaccat
    33481 gggttgttcc aggcacatta cttgtagcaa ttgcactcgt tggtttcgtt acggcaccga
    33541 aaaacgctgt aacagccgat caaaaacaac tgcaggcaaa aatcgctgaa agtaaaaaat
    33601 tagcagaaga aaccagaaac aattcagaaa acaccactag ttcggttgac caagcgatcc
    33661 ttgataagta cgagttgtcc aaggcacaag ggaataaggc acaaaaatta gaactaacgg
    33721 catttggtga ttcagttatg ttggatgctg caacggatct acaagaactt tatccaaaag
    33781 tagtggtaga tggagatgtc ggacgacaat tatatgccag tgtaccgtac attgaaaaat
    33841 taaaggaaca agatttgttg aaagacactg ttctgatcgg actaggaacg aatggctcat
    33901 tctcggaagc tcagtttgat agtgtgatgg atgcaatcgg tgatcgaaaa gtatactggg
    33961 tcaatgtccg agtaccgacg aagcgctggc aaaatgacgt gaatgcgatg cttgaacaga
    34021 tgacgaaaaa atacgacaat atgacgctga ttgattggta cagctacagt aatgaccata
    34081 gtgactggtt ttatgatgat caagtccatc caaatcctga agggatgaca cattacattc
    34141 acttagtcag cgaagccttg ctaggaggaa gttcaagtac gaacagcagt gagacaaacg
    34201 tgacagaatg atagctacaa aaaacttcag gcaaaaacat ttgtttttgc ctgaagtttt
    34261 tttatattta ccgtgttttt aacattcata tagattcagg aagcaaaacg gttgagtgtg
    34321 tctgtaaata acgttctttt tgttttcggg tgagtttttt gaatgcagct tctgcttttg
    34381 ttgcttcgct tcttgaagaa aatacttctg catggatcat cttaacaggt cttctttttt
    34441 gaagacgagt atatttagca ccagtaccat tgttatgttc ctctaatcgt ctagaaagat
    34501 cggttgtata tccaccataa aatgtctgat ctttacagaa taatacgtaa aaataatgtt
    34561 catttgccat agagcatctc acgaatctct gcagtgtatt ctccatccat attgtaagtg
    34621 atcaatggtg gagcgacttt gaatccgtct aatttgcctt ctttgattcc ttcaactaac
    34681 aaaatatttg cctcttttcc aggttttggg taaacaaatt ggatcctttt aggtgcaatt
    34741 cgatagtctt ccatgacctg aatgatttct aagaaccgat caggacgatg gaccatagta
    34801 aagcgtccat ttgtttttag tagcttactt gaaatatcga tcacttcttc taacgtcgta
    34861 tgaatctcat gacgggcgat tgccaggtgt ttattagggt tcgttttatt tgttggcagc
    34921 cctttgaaat aaggtggatt acagacgact aagtcacaag aattatgtcg aacgacagat
    34981 aagctgtctt tcagatcgat ggtgtggaca gtcatttgtt catttaaatg gttaagcgcg
    35041 atactacgtc ttgccatgtc tgctagacga ggttgaagtt cgatagcgtc gatagccgcc
    35101 tgggttcgtt tacttaaaaa aagtccaact gcgccatttc ctgcacaaag gtcaacaatc
    35161 ttcccttttt taggtacacg ggaaaagtga gcaagcagca cagcatctaa agaaaaagaa
    35221 aacactttgg aactttggat aatcttgata tcttctgcgt ataattggtc gattcgttcg
    35281 tcttcgtgaa gcatggattc cctccaaaat gaaaaaaata gtcgtctgta ttatactatt
    35341 tttattaaaa agaaccaagg tggcttgtca aacctctatt ttttatgcat actatgacca
    35401 taagaaggga aaggaagaga ctatgtttta tcgatttatg cgcggggtag ttcgagtact
    35461 attagcctta gttaatggaa atgcccgcta tgagaataaa gaagttttac cgcaagatga
    35521 gaattacata ctagttgctc cccatcgtac ttggtgggac ccattatatc tggcggtagc
    35581 tgcagcaccc aaggaattca gctttatggc aaaagaagaa ctgttcaaaa atccagttct
    35641 gcgatttata ttaactcgat ccaatgcttt tccagttaaa agagaaaatc caggaccaag
    35701 cgtcattaaa acacctgtaa agattttgaa atcgacaaat ttgagtttga tcatgtttcc
    35761 cagtgggaca agacatgcta cagaacttaa aggcggaatg gcattgattt ccagaatgtc
    35821 taaagcgaaa atcgtgccag ctgtatatca aggtccgttg acacttgggg atctgttcaa
    35881 gcgtcagaga gtgacagtgc gtttcggcga accaatcgac ttatcagata tcaagaaaac
    35941 ggataaagaa ggtatggcgg agatcgaacg acgaacacaa gcagcttttg acaaattgga
    36001 caaagaagtg aaccctgatt tcaaatatga agtcaaaaaa aaataaaatg ataagtttat
    36061 gcgtgggcgg tcttttgaat ctactgtcct gttcagttca gactttttca atgaaaacga
    36121 gggagagacg tcaagtctgc cctctttttg cgttccaata tgtaaaatag aagacaggtg
    36181 tcatgtaatg gatcaaagtg ttataataat tagaaggaca ttttttgagg tgattgaatg
    36241 cgttttttac atacagccga ttggcatatc ggaaaaaaac tacaaggtta tgacttgatt
    36301 gaagaccagc gtcatgtact atcttctata ctagatatcg cgaaagaaga aaaagtagag
    36361 gcaatcgtga ttgccggaga cttatatgat aggagtgtcc cagctgttga tgccgtagaa
    36421 ttatacaatg aattgatggt cgattggaat ttaaaggaaa agatcccgat ttttgctata
    36481 tcaggaaatc acgatagcag tacgagactt tcagcgggta cgccatggtt cagttattcg
    36541 aactattttt tgcgaacaca gctagcagaa gcatttgaac cagtcgagtt taaaaacgta
    36601 caatttttct ttcttcctta ctttgaacca attgcagcga gattatattt tgaagatgac
    36661 aatatccgaa cgatcaagca agcggtagcc aaggtgatag ataaaatgca ggagctattt
    36721 gattcagaaa aaaaacaagt attgattagc catttttttg taatgggaag tgtaaaatct
    36781 gattcggaaa cgaaaatcga agtaggcggg ttggattcga tccctggtga actacttaca
    36841 ccgtttgatt atgtagcact aggacatttg cataatcaag ctgctttgag acaggataat
    36901 gctcgctata gcggttcccc attgaaattc tctttatctg agatcaacca aaaaaaaggc
    36961 gtatggatcg ttgacctgac aacaggcctg gagttgaatt ttagggagat cgaacccctg
    37021 catgatattg aagaaataac agcgagtttc aaagaattgc tggatcctgc cttttatcag
    37081 tccgtcaatc gggagaatta catctatatc tatctcactg atagaacgat catcccgaat
    37141 atgatgaacc agcttcggca aatatatcct cgtattttgg ggattgaacg ggcaaacggt
    37201 cgagcagaac aaacaaagcg caaacgaaaa gtactagaaa tgaaagatcc tcaaaaatta
    37261 gcagaagcat tttttagtga aatgacggaa gagcagctaa ctgcaaacca agaaaaatgg
    37321 ctcggagaaa cgttgcaaga aatcatggaa atggaatgat caagaatgaa accgaaaaaa
    37381 ttacaactta aaaattttgg tccttttatc aatgagaccg tagatttttc acgtttgaca
    37441 gaagcaccgc tttttttgat cagcgggaag acaggagctg gcaaaacgac gatttttgat
    37501 gggatcacct tcgcactttt tggtgaaact tccggaagac ttcgctctgg aaaagagatg
    37561 cgttctttgt ttgctacacc agacgaagaa acaagcgtga ctttttcttt tgaacatcag
    37621 cagatgagct atgaaatcga acgaaaacca gaacaagttt tagcaaaacg aaaaggaaac
    37681 ggaacaaaaa aacaggcagc caaagtaacg ttgaccattt ttgatgggaa aggaaaagaa
    37741 ataaaacaaa tcacaaaacg tacagaagca gatcagttga tcagagaact gatgaatctc
    37801 gatgcgaaac agttttctca aatcgtttta ctaccccaag gagaattccg taattttttg
    37861 gtttcatcaa gcagtgataa agagactgtt ttacgtcatt tattcggtac tcaatttttc
    37921 caacagttca atgagcgatt aaaagaaaaa gcaaaacaac agcaacaaaa attggatcat
    37981 ttagagcaag agctgcatct tctgcaaaaa aggtttgttt tagtcaaaga agaggaacca
    38041 gcagcagggt ttgaagccgt tttagcccaa tggacaaacc atcaggcaat actcgaaaaa
    38101 caaatcacgg aagaaaaaga agctctaacg gaacttcagg aaaaacaaaa gcaactagaa
    38161 aattcctact atcgttttga aagcttgaaa aaaagttatg aagaaaaaac gatattaata
    38221 aacaagcaaa aggaattagc tgctcaaaaa gacgaaatag aggaaaagaa acgatggatt
    38281 gggtattatg aatttacgca acgattagtc gaaccaatcc agcgcctaca agaaataaaa
    38341 gttgaaaaaa tagaactgtc acaaaaaagt agtgagcaaa caaagaaact agcgatgact
    38401 acgcagaatt atgaagagtg gcaaaaaaat gaagcaaacc gcgtacgccg acaaacaaaa
    38461 atcaaagaag ctgctcaaaa actgcaaaac aaacagatga tggtgccaat tgtcgaatcc
    38521 ttacgtagta aaaaacaaga cgcagaacaa ttaacaattt cattggataa agaagaattg
    38581 aatgccgaga agctgtatca aaatctcgct atctatcagg aaagaactcg aattcttcaa
    38641 gaaaatttac tggatcagga aaaactgcaa gaagatcgtc ttgcttttgg acagttaaaa
    38701 tatctagatg aaaagcagca agaaatagaa aaacaaaaag caaaagacac tgggtcgctc
    38761 gcacagataa gagaagaact caaaaaagca actgaagaaa taacaaaaaa tagtcagcta
    38821 ttgaaagaac agacagaaca agcagaacag ctgaaaagcc aatgggcaaa gcagcaaatt
    38881 gctcgtcttc agcttttttt gcgtccaggg gagccatgtc ttgtttgtgg atcaacggaa
    38941 caccccatac aacaattaaa acacgaacag ccaaataagg aagatatctt aaaagtagaa
    39001 caacaactgg cagaagctga gtctgctgta gaaagaactc agcaaatcat tgccaaaagt
    39061 gaagcacatg aaaataatct tcaacaacaa ttatcagatt tagaacaaaa aatcatggca
    39121 acgaatatac aattggctga acaagaagaa cacttgcaac aggctttgaa aaaggcattt
    39181 cctgagataa cagaacaaaa aacaaaaaca actcttgtag taatcgaaca atctttagat
    39241 agacgaaaaa gcaagatggc caatgcaaga atagagctgg aagaaataag acaacaagca
    39301 gaaaagctcg aacaacaatt agctgtctac aaacagcagc agacagaaaa aaataatcag
    39361 ctccagcaac tgcaaggaga aatcaaaagt ttagaacaac aattgcaaga tacggatagt
    39421 aactgtttag aagaggagat acgacgactt gaaaaacagt tagaagaaga ctcgaatcaa
    39481 ctagctgttg agcagaaagc aggagtgcaa ttgttgcaag atcttcatac gcttcggaca
    39541 cagcttgatc ttcaacatga acaaatagaa aaaatagatg aaaaaataga aaaggaacaa
    39601 gaaagaatag ctaaaaagtt agaaagccag tcgtattttt caacaattga agaaatctgt
    39661 gcatttgcac aacagcaagc acaatataaa gaaaaccaac gtacagttac ttcttatcat
    39721 gaagagcaat tagtgacagc tgaccggctg cgtcaattag aaaatatcca gctaactgag
    39781 acattcccag atacagaaga gatcagccaa cagttagaag aaataagacg tatgatcgaa
    39841 ataaagcaag aaaagatata cggtttacaa gaacaaaaaa ttagtaatca aaaaatctac
    39901 gatgaatgtc tttcgattta tcacacaagc cagacgaaat tagatgagct tacgcaatta
    39961 cagcagcttt cgcaaacatt caacggagaa aatcctaaga agactagttt ggaacggtat
    40021 gtgcttcagg tttatcttca agaagtgtta caagtagcaa atgatcatct ccaacgttta
    40081 acgaaaaatc gttatcaatt tgagctagcg gataccattg gcagttatcg agggaaaacc
    40141 ggattagaaa tcaatatcta tgatgatcag gcaggtatgt ctcgaagtgc gcataccctg
    40201 tctggcggtg agagttttat tgcagcactt tctttagcat tagctcttgc cgatgtgatc
    40261 cagacacaag ctggtggtgt agcaatcgat gcattgttta ttgatgaagg atttgggtca
    40321 ttagatgaag aagctttgga aatggcaatg gaagctttag aaacgatcga aagtgaagga
    40381 agaatgatcg gcatcattag tcatgtaaga gaattgaaag aacgagtatt acaacaaata
    40441 agaattgata cagaaggtag cggacaaagc aaaatacgct atcaacttgg ataaaaaggg
    40501 agattggtaa ctatgaaatg gagtattcca gaaaaagtca ttgcacgtgg acgtcaatac
    40561 ttgcaagaag gccgagtgtt atcggttgtc cctgaccaag aagaaaacgt gtggcatgca
    40621 gaagtcttgg gcagtgaatt gtatatggtt gatttggatg gtacagcaaa agagatagat
    40681 tactgccaat gtccctattg ggaggaacat aaatattgta agcatacagt tgctgtggaa
    40741 ctttatttac ggtcgaaaaa tctatctcgt atcatgaaaa aagaccagcc aatgctagaa
    40801 ccggtaaaag caacaagtga gggagaaatc attgcaaaag gtttttctcg tctaaaaaca
    40861 caaaacaatc ctcaagcggt gcaacctttg attattgaat accaagtaga aacgattgag
    40921 actaatcagt atcacccaga gctttctatt ttggcacttt acttgcgtat cggttcattg
    40981 gcatcaccga aaaaaacata tatcgtaaaa aacatctatg attttttaca agcttacaca
    41041 gaaaaagaaa cttacactgt taataaacag taccagtttc gtctagataa acgggcgttt
    41101 caaaaagaag atcaaaaaat actcacgcat cttgcaggaa gtgctcagac gcatcaatta
    41161 ttaggtacga acggcttaca agtcaaagga aaactagata aaagatatct gcttctccca
    41221 gtagaacaag cccgcttcct gttagagcag atgaatcaga ctacacgttt gcatctgcag
    41281 ataaatgaac aaaacgatca aggaatacaa ttttccgatc aaaacaaacc tttatcattc
    41341 aaagtggaaa aatttggaga agattatttg ctgcaagcat tgaatgattt tgattttttc
    41401 tttatgcatt atcagtgggg agttatccaa gggacatttt attctctgac gaaatatcaa
    41461 caaacggttt atcaaacttg gaaacaattg attcgccgat tggagaaacc agaagtagtg
    41521 ttcaagaaaa aagaattacc gtctttgttt aaagagatta tccctctgct gtcagagatc
    41581 ggcgacgtag ctattgcccc tgcagtagaa gaggaagtag cagatatccc cgtcgaattt
    41641 attttctttt tccgaaaagc aaaaggaaaa atccaagctc gagtcgattt cgtctatggc
    41701 gaagtcatct attcgactga cccgaagcat gaggtctcga cagaacaggc ttttcaggtg
    41761 ttacgtgaca cagtagaaga gaaacgagta cttgatctat tcagaatgta tcgctaccag
    41821 aaaaatgaaa ctggttatga acgtccattg ccaagcgggg aagaactata tgcctttttc
    41881 cgcacagaac tatctgtctt ccgtcagttt ggtgaagtca gacttggaag aaaattgcga
    41941 gagttgtatt tagatgcgca taaacatcaa ccgaaaatcg aagtaaccga gaccggttca
    42001 tggctcgata ttcgattcga tgtgacaggg atagaggagc aagaaatcga tcatgtcctg
    42061 caaagcttgc tgagaaatga tgctttttat acattagaaa atggtcaggt tctttctttt
    42121 gattcagaag aatttcaaca aacaagccaa gtgttgcaac aattacggga atcgatacgt
    42181 acagaagaag gaacgatcca tgtacctaaa aatcaaggat tgatcattca aaatcaattg
    42241 gaaaaaagca atgctacttt tagtgaatcg ttccaaacga tggtacaaga tctcattcat
    42301 ccagaaagat accaggcaca gcttcccaaa ggattgaatg caacgatgag agattatcaa
    42361 aagcaaggtt ttcgatggtt gaagatgtta ggtcattatc agtttggcgg tattttagcc
    42421 gatgaaatgg gacttgggaa aacactacag acaattgcct ttttactttc ggaaaaagaa
    42481 gaacggaaaa gcttctctgc tttgatcgta gcgcctgcga gcttaattta caactggcag
    42541 gcagaggtga gaaaattcgc cccttcttta agtatccaag taatcaatgg gaataaaaaa
    42601 gaacgtgaag aattactggc taaagacaca gatatccgag tgacttctta tgccagctta
    42661 agacaggatc tagctaatta tcagtcgcaa aaaattgatt atttgattct tgatgaggca
    42721 caaatggtca aaaatagcag tacgaaaact gcacaagcat tgagagaatt agctgtacct
    42781 cagcggtttg cactgagtgg gacaccaatc gagaataatt tagaagaatt gtggtcattg
    42841 tttgcaacga ttatgccagg atttttcccg actaaaacaa aattcaggga acttgccgca
    42901 gaagaaattg cgcaaatgat tcgaccgttt attttacggc gagataaaca aactgtgttg
    42961 aaagacttgc cggaaaaaac agagatgaat ctatattctg cacttacaga agaacaaaaa
    43021 actgtttatt tagcttactt gcgtcaaatg cgtgaagaaa tcacatcaat ggattctgaa
    43081 gcattcaaga aaaaccggat cgggatactt gctggtctga caagactgcg acaaatttgc
    43141 tgcgatcctc gtctgtttat tgaagattac caaggcggtt ccggcaagct cgaacaagta
    43201 aaagatctac tggtagctgc caaagagaac aaacgaagag ttttgctgtt ttctcaattt
    43261 acagggatgc tgactatctt gcaagaagag ttagccgagc tagggatctc gacattttat
    43321 ttaagaggca gtacgaaacc acaagatcgg ttaagtatgg tagacgcatt taatgctggc
    43381 gaaaaagatg tttttctgat ttccttaaag gctgggggaa ctggattgaa tctcacggga
    43441 gcagatacgg tcatcttgta tgacctttgg tggaatcctg ccattgaaga acaagctgct
    43501 ggacgtgcac atcggatcgg acaaaaaaat gtggtagaag tgtggcgtat gatctctgaa
    43561 ggaacgattg aggaacgcat ggattcactc cagcaagaaa aacgcgaact gttccaaaaa
    43621 gtgatccaag gtaatgaaga acagttgacg aaactgactg aagaagacat ccgcatgatt
    43681 ttaagtgtag gagaaatcga ggagtaagag actcgaaaaa gcgttcagta atgggtaaga
    43741 aagcctttct aaagaagcga ttgtttattt gatttaaaaa atagcaagga ggctgggatt
    43801 ccattttatc ccagcttcct tgctatcatt tttttatttc tatttttaaa ggttatacaa
    43861 agattgtctt cattgtctct aacagctgat caaaagaaga aatctcgata tcgcaaattg
    43921 gagtctgttc aattttgcgt tctcgatggt tgaaccaaag cgcttgccag ttagcacttt
    43981 ttgcacctag aacatcattg tcgtaattat cgccaacgta taaggtctct tctggaagca
    44041 tatgaaattc tttctcagct agctgaaaaa tctctttttc tggtttttgg aaacctgttg
    44101 cttgagaaat gagcatattg cgggaaggaa tccaattgtt caattgaagt tgcttcagtt
    44161 tttttgtctg atggtcagtc ggcccatttg tgataattcc taatgggaca ttcttttcct
    44221 tcaagaaatc gagggttttt ttgacctcct catgcaagca gatattatca agttcttcct
    44281 cgtaaatttt ttgaaataag aggccatctt cttccgtaat atgagggtag tctaaatctt
    44341 ttagtgattg gctgatccga tgtgctcgca tatattctag tgtccaatct cctgccatta
    44401 cttttgggaa gttttcatca ctatgatggc ggaaccggat atatagtgga tgcatatctg
    44461 catctgaaac aagcggaacg actcttttga ccgcgtttcg aaatggctgc tgctgatcat
    44521 acatcgtatc atcaacatca aacacaactg atttaatcaa aattttacac gcctttcggt
    44581 tttcattgat tttttcacaa atccttgact attgtaacag aaaaaattgt ctaaaaaagc
    44641 tgataaataa aggtttttct tactatattt ctatttcctt gacagaataa ggtttttata
    44701 tttcagtttt tttcactaaa aatcgtgaaa cacgtcaata agtttgatga acaaattaat
    44761 cattatggta gaagtcgatt gatttatttt aatgcaatct ctgtggaatt ttcgaaagat
    44821 ttattttttt aatacagtct caatataact attcaaacat aaaataacgt tatttgat
//
LOCUS       DACGEU010000012        43395 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.012, whole genome shotgun sequence.
ACCESSION   DACGEU010000012 DACGEU010000000
VERSION     DACGEU010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 43395)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43395)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43395
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.012"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            <1..649
                     /gene="mutM"
                     /locus_tag="IXR40_000636"
     CDS             <1..649
                     /gene="mutM"
                     /locus_tag="IXR40_000636"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HAQ4360508.1"
                     /translation="HLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDGSQLRY
                     NDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKPLLLDQ
                     RLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGGTTIRS
                     YLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKIAK"
     gene            613..1242
                     /locus_tag="IXR40_000637"
     CDS             613..1242
                     /locus_tag="IXR40_000637"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HAQ4360509.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKKKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEKLVGQIENWLFANRFL"
     gene            1294..1626
                     /locus_tag="IXR40_000638"
     CDS             1294..1626
                     /locus_tag="IXR40_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HAQ4360510.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHIPDEQKIEEQRMKH
                     YTGIEEKL"
     gene            1938..2429
                     /gene="nrdR"
                     /locus_tag="IXR40_000639"
     CDS             1938..2429
                     /gene="nrdR"
                     /locus_tag="IXR40_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HAQ4360511.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            2452..3825
                     /locus_tag="IXR40_000640"
     CDS             2452..3825
                     /locus_tag="IXR40_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Replication initiation and membrane attachment"
                     /protein_id="HAQ4360512.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            3825..4751
                     /gene="dnaI"
                     /locus_tag="IXR40_000641"
     CDS             3825..4751
                     /gene="dnaI"
                     /locus_tag="IXR40_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HAQ4360513.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            4880..5320
                     /locus_tag="IXR40_000642"
     CDS             4880..5320
                     /locus_tag="IXR40_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HAQ4360514.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            5464..6165
                     /locus_tag="IXR40_000643"
     CDS             5464..6165
                     /locus_tag="IXR40_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HAQ4360515.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            6162..7283
                     /locus_tag="IXR40_000644"
     CDS             6162..7283
                     /locus_tag="IXR40_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HAQ4360516.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            7298..8530
                     /gene="pepT"
                     /locus_tag="IXR40_000645"
     CDS             7298..8530
                     /gene="pepT"
                     /locus_tag="IXR40_000645"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HAQ4360517.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            8662..9570
                     /locus_tag="IXR40_000646"
     CDS             8662..9570
                     /locus_tag="IXR40_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HAQ4360518.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            9605..9877
                     /locus_tag="IXR40_000647"
     CDS             9605..9877
                     /locus_tag="IXR40_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HAQ4360519.1"
                     /translation="MDVLLHNPLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            9888..10934
                     /locus_tag="IXR40_000648"
     CDS             9888..10934
                     /locus_tag="IXR40_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HAQ4360520.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            11185..13794
                     /gene="clpB"
                     /locus_tag="IXR40_000649"
     CDS             11185..13794
                     /gene="clpB"
                     /locus_tag="IXR40_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HAQ4360521.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQSNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(13945..14616)
                     /locus_tag="IXR40_000650"
     CDS             complement(13945..14616)
                     /locus_tag="IXR40_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360522.1"
                     /translation="MIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGITFIVES
                     LLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWDKILHA
                     VSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLCDQFLG
                     MNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFESYKLE
                     KVKNT"
     gene            complement(14609..15103)
                     /locus_tag="IXR40_000651"
     CDS             complement(14609..15103)
                     /locus_tag="IXR40_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HAQ4360523.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            complement(15123..16343)
                     /locus_tag="IXR40_000652"
     CDS             complement(15123..16343)
                     /locus_tag="IXR40_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4360524.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            16490..18325
                     /gene="lepA"
                     /locus_tag="IXR40_000653"
     CDS             16490..18325
                     /gene="lepA"
                     /locus_tag="IXR40_000653"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HAQ4360525.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEQDSVK"
     gene            18521..19432
                     /locus_tag="IXR40_000654"
     CDS             18521..19432
                     /locus_tag="IXR40_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4360526.1"
                     /translation="MVDNSSGRVLKSLRKEKKLSQKKLADLAGISQSTLVKYEKGSRK
                     IPKDVDNTLSKILNIETLIKDEEDKIEILIGKLIAYRDMNKLLNKELADNIGISEVLL
                     SYVLNRKRNPSKEMQKKIDIFLLSNEKEILKEINRDSEIFSLSKDDKIVMGKRIREVR
                     KNREETLEKFGKNFTIYTGKNVISRWEKGINIPDIEKLMNIAYLGKVTVPYLMYGEDY
                     KNILPKDERVSDFKKINSFSMGLRMRKIRKDYYLEREEFGKLFSPSISKWSIDRYENG
                     RDIPNTNRIIQYAYIGNLSLEFLIYGI"
     gene            20428..20679
                     /locus_tag="IXR40_000655"
     CDS             20428..20679
                     /locus_tag="IXR40_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360527.1"
                     /translation="MRKVLVFNTRGQSFLGIEGTRVTVDGWCDCFEVGKHVELMAFTE
                     LKDKNNVEFFESDIGWDDHEEVYGKFILRKGNSYTNGEA"
     gene            20762..21034
                     /locus_tag="IXR40_000656"
     CDS             20762..21034
                     /locus_tag="IXR40_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360528.1"
                     /translation="MSDGFEQVSIIKNQVREILRKKGYLVDSYFEGDYETWVGVYARP
                     ENKPTYLDPTTSEDAYLQNRYRVDGFKQDFAEWFEWEIENGEVKEE"
     gene            21124..21363
                     /locus_tag="IXR40_000657"
     CDS             21124..21363
                     /locus_tag="IXR40_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360529.1"
                     /translation="MIDISLPEDLKPDPVTIGNSVMIFDSLDEAMSYGWKEIKDEGSN
                     WYGMRFGDGEVAKKAGIPIGKWTVDFHEAGSFFVL"
     gene            21510..25793
                     /locus_tag="IXR40_000658"
     CDS             21510..25793
                     /locus_tag="IXR40_000658"
                     /inference="COORDINATES: protein
                     motif:HMM:NF019941.1,HMM:NF037291.1,HMM:NF037639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VaFE repeat-containing surface-anchored protein"
                     /protein_id="HAQ4360530.1"
                     /translation="MYAKTKMNWLKALALVAFSQFCFLVGTAQAHAEETTAIQPTMEA
                     IAQVASEVTEVQPAEAGVPAGEATVEQAPVTEAPTVNSKTTLDQTIGETQHPGNSPGT
                     SQPVEETASITTPASETSTLEGEKAAEATPSVQPESSEKQAEEKKRIEETVEQPAATA
                     DKEGKNEENVEKTISSTAASQNQPTKPNKESTASIENQKKKEQNIPKTGTPTLLVTVP
                     TNRSVRVRRATNAAVLGGRKIDWGENIGVTSSPNNLNFTLNYMVRFEINGQVAFCIEP
                     GVSAAEGQVYTATALKNYLKNSNVRKKTSLISYLGYVTNKDKSDEQYIAAQFMIWEAL
                     GTKIPIKNIRVDYDRRKAEIQRLINNFGEKATFNNQTHTVKIGETLKVKNKNDFLKYV
                     KDIQKPKGVNVSIHGNEVWITVTKEAPDKAKIQLNKIKVQGAPLAYRRPGAQTIGVLH
                     PTEPNASVINLQILKQGNIRVFKEDAETGVKAQGAASLENAVYGLYQADGKKIKEITL
                     KKINGKVQAEIKDLDPGKYVLKEIKAPKGYVLSDEAIEIVVEPGKTVNATAKDQVIKG
                     TIDLVKVANKDLVDSTNPDNKPKLAGIEITLTSKTTGKVVKTVVTDNDGYATFGKNTV
                     VFDTYILSETKGKEGYKLFEPLEVTISENGQTFHYVLEDKVIEQRLKVVKVDQETGKV
                     IPLANTEFKIFDTLANRYVTMEIPNDTETTDIFKTNEKGFFLTNGTLTYGKDRYRLEE
                     IKAPVNYVLNQNPLVFSITNDTEPIKVIHFANRQARKSVKLFKYEEWNKKKTPLAGVN
                     FTLYNGKNQAIGEYTTDQNGEILVKGLVADDYYFLENAPLESFQPNTDKQAFTVAFKQ
                     NAPDDGETLVVSVRNYLIPPKLETQASNKADGEKVVDPLETIVIKDSVSYTNLFVGKE
                     YTISGVLMNKATNAPILQDGKEITSTLAFIADKVNGTKDLEFVVNASVLKGQTIVVFE
                     KLFRDGIEVAAHADINDEAQSVKVNNPTVHTTAVFEDGLTVADPTGLFTLNDTVEITE
                     ILPGKAYLVKGILMDKATGEPLLVHGNTVETSVGFIAKAENETVIVPFTFDLTGINGR
                     EIVVFESLFRNDEELANHKDINDKGQTVRVTNPSVRTTATHKPTGLKEVNPLTKVTIT
                     DAVKYHDLVVGKTYTVNGVLMDKVTEKPVLVDGKEVTSTLTFVAETTDGTVNLDFILD
                     ARALRGKEVVVFEDLFREGVLLASHADITDNDQTIKISNPTITTKATNKNGGKEILAL
                     PNQTVLEWVKVDGLAIGQIYRLIVQGYLTPDGTPFEGTHAEKVFAADKEMMEFLFEFL
                     VDGRNLAGKGLSFAEWLQAKTEDEKETFEEVAKHNVDLTNKDQTVQIVEAPKPPQPVK
                     PEQRVKPATVVPMLPKTGEQTSSILMVLGLVVLVIALGITLYKVRKAKD"
     gene            25892..26257
                     /locus_tag="IXR40_000659"
     CDS             25892..26257
                     /locus_tag="IXR40_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360531.1"
                     /translation="MAEKALRMKKEFLGQVFLLGSREPNPPKEINGVSGRYVQLQAEC
                     SREEQPAFFVYLTAEEDKRLRLPEKEVRISFEEAYFVFRKERVNSRETNDMGQTERRT
                     TGYQDVGVFLTGVKIGEVL"
     gene            26259..26711
                     /locus_tag="IXR40_000660"
     CDS             26259..26711
                     /locus_tag="IXR40_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360532.1"
                     /translation="MGLKFPNNYDITEALDETCLGAVRFGALEESDRVFDNETGDYTG
                     EIRSQRAQLVFGNPDEPKIARRVKFPADVDLTGFKRRDPVKLIDPEYHVVYIPAQDGN
                     REYSDLVIYAKGLEKVEAPTNNPNMKQSQEKGLDQKQPSVDSKEKEKK"
     gene            27325..28635
                     /locus_tag="IXR40_000661"
     CDS             27325..28635
                     /locus_tag="IXR40_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HAQ4360533.1"
                     /translation="MYLIPGISIVLYLLLVSGLILGLMHWSRLKEGYFASVYWRQLLV
                     RMLIDNRFVYTKKQVSEKQTREKMRLPKVYFYQKKQELVVSFPLDGGRFHERFLKMGH
                     LLSEVFLRDLIREEREKARINYVFLSDSGRIPIDQCIAENGRIHLMKTLDWVYDQSPN
                     MLIAGAIGGGKTYLLYSLIQACLSVGTVDICDGKAADLAALGDVDVFKGHVFYKINEE
                     MIICLRNALKEMNQRYAYMKTMKDPKYEPGKNYAYYGLPPHFIFFDEWAAFYGSLDME
                     ARNRVDKLIQPLVLKGRQAGMYIILAMQRPDAEYFPSGVRDNLTFRISVGRLSPIGYL
                     MTFGEDFKNKPFYNKDQPGRGYAFPGFDVPVEFFAPFVYKDYHFIKEFEKFTEMIVYD
                     FTVKEDSQDQTMGDDNQLLQEQLERQMYLAKDPKGTSFSDAHIL"
     gene            28658..28969
                     /locus_tag="IXR40_000662"
     CDS             28658..28969
                     /locus_tag="IXR40_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360534.1"
                     /translation="MAESCYYRVATAIRMINPSLSSRTFYDWLNRIEQVTDYRFLRKE
                     RVFTGKVINQVLLTKKDIERLTRLYHYRVDLEEDLTLSIYRVFSPEKYSEITKLDHLI
                     L"
     gene            29330..30586
                     /locus_tag="IXR40_000663"
     CDS             29330..30586
                     /locus_tag="IXR40_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAQ4360535.1"
                     /translation="MTPIELKSYRKKLSAIHNISGDKKPLSQARFAQLMGCSKDYIRK
                     MEQGKRKIPEDFEQRIKERFRLYMKSGIDLRAMIDYLRLSFFGTDYKTVIQRVLRMDL
                     TEFETRPTGLYLFDCLSVRGNIWVFWHSKRTVTENVLVQFSGQGCREYEEVMREQQTD
                     WRTWLYSIWKNQGKLEAGYTRVQCSRFDIALDELWGLETEEHFDLFELLEKQKAGLLE
                     MDFKRFQNIGGCFLDDGYFRSEGLSLYFGSRKSPLFFNFYEKRFEIANREKISELEAL
                     TKYGIYNRYELRLANEKATQAVEAFILGDSPKRLGEIGVGLINAKLIVWDRLESDARI
                     VDKRWAKLFRSMEELDFTVKPEKFSLDRSERWFLKQVAPTLKLLQEADRILGRDFVQE
                     GIDNAELNDEQQNYLEWMGTSGGKIA"
     gene            30583..31128
                     /locus_tag="IXR40_000664"
     CDS             30583..31128
                     /locus_tag="IXR40_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360536.1"
                     /translation="MNAYTTTEWLRLLDLKAAIEALNEKMVDLSYFRFRVPYIEQAVK
                     AGRYQEKENWQEIARLLEVRKGYEQELEELEFSRRKGRLEFIRFYRFSLPIPAILAVK
                     KGCDKMKIYENCVAALSSEKPLMEEISLVTVTWEMSRQPTEEQTYLSLEEIEIELEEI
                     GRYATCSTYCGSVISIAGVIV"
     gene            31129..31629
                     /locus_tag="IXR40_000665"
     CDS             31129..31629
                     /locus_tag="IXR40_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360537.1"
                     /translation="MKKIMIYVGAYWSRDPTVLENPEAVHYCLRQLFYLYKERLESLI
                     RQLPYTDRRLDELLLRYPAMYKRRKNRLLPEEYPIEKHELEGRFVAYFYDDVRMRLVE
                     QRMEIENDRYYFINYCKKRKYQVTDDFYDCILQDGEVILSKIAPSFRELVPIDFLKKC
                     HLRILP"
     gene            31710..32266
                     /locus_tag="IXR40_000666"
                     /pseudo
     CDS             31710..32266
                     /locus_tag="IXR40_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353559.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            32286..32630
                     /locus_tag="IXR40_000667"
     CDS             32286..32630
                     /locus_tag="IXR40_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360538.1"
                     /translation="MWRLLFLVVCGMALFYVYRVYLYPRMERWTSWYRDPLKQRKGLK
                     RYRYELLVEFSDGRQAQYYFFANYPKYNTSELLIQLFKNNPYVGLEENGREFFYRSDN
                     ISAASMNKTRIA"
     gene            32649..33560
                     /locus_tag="IXR40_000668"
     CDS             32649..33560
                     /locus_tag="IXR40_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAQ4360539.1"
                     /translation="MKKTTLAVVTTLGISLFSFQLGSSLVYADETVETPKSEIVETLP
                     GEGLPDVETELNGGTTEKPAEPEQLQSEKPEKEPVTPEPEFPESTLPTDSIEEEGVHS
                     STTTDSSIVTTPEQSGTTSSSEKNTDSSSTEQPTMSSTSEEQKEEPKQPVEKSEAIPK
                     ENKPIVPAKEVTVSVTPSGEITTNTSQGMSVPIVTSNVEELTHIPTPTTPLKVAGDQT
                     IVGVKDGIPLIQDSEGNLVKDLSIPVKKLPSGNIEIKTADGKTKVLPKTGEEIHVALS
                     VLGGVLTSIAGFVGYKRKRKGIENEGN"
     gene            33639..34631
                     /locus_tag="IXR40_000669"
     CDS             33639..34631
                     /locus_tag="IXR40_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAQ4360540.1"
                     /translation="MKKRQLRRKEKVYTEKVPKQKKIHSKKAVKWIWCLVLFLCFSGG
                     LAFFQSMKTKVQVSFLKDEIQQLQKKEVQSRSELTYTPEIESFMNRFVALYMNTFDNH
                     EQEQQRQETLKKEFYAQNFIQEPGSVSGVRKLTAASFIGLKEIETIPTASYKVTYDIR
                     SMNPESKKETSVTITQVLNLPFSISNKGCRIIAYPYFTALPKNTEKQRMITYDDTLYE
                     TVDASEAKDVEGFVEDFLDKYAKNNAKDMSYMMKEPEGLNQTAKVDQVEMKVLRYKET
                     KKPFIVKATVVFRDGDTSLLQKEQMTIVITKKTNQYYVEKLTHNWLDRKGEERK"
     gene            34628..34846
                     /locus_tag="IXR40_000670"
     CDS             34628..34846
                     /locus_tag="IXR40_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360541.1"
                     /translation="MTLKGIVDFILTQGGYFLIMVVVYLGLRNFMKSKVGNALISIAA
                     GAAVYFFLNDPTRVFDAFGKIIEKLFMD"
     gene            34859..35269
                     /locus_tag="IXR40_000671"
     CDS             34859..35269
                     /locus_tag="IXR40_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360542.1"
                     /translation="MDWEPYDYSIVYAEPYRVQQITSNWRLPFPVALVNAATFLLVVI
                     FEYLFLRSFIGWVISFFPPAGVVFYIGLPYLCVLALAKLKPDGKKVHFYLWDWFCYMI
                     RMMNGDCVYYNWDKVSNNALEELLFVNKYVYLED"
     gene            35321..37849
                     /locus_tag="IXR40_000672"
     CDS             35321..37849
                     /locus_tag="IXR40_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HAQ4360543.1"
                     /translation="MVLVKEPVKAFKKNCLLNGEDCIWAYYHVFPRTISKNTPKKTQE
                     IKEMMARLLLLLADYEDVELVMYPRTMNLRTKFDTLGKGFSPDSQAIGAYYAKETVTL
                     LEREGQVYRPSFILGIKVKEKATVESFHDVINLIWLDLAGSLARLFGLEVDDLETLFS
                     ESDPYVKEVTQLLYSFSIRPLVKKELLYLNRLQYIRGMAHKVEEQNNWEVLKDNQGTY
                     VRIPKEHKGLLQLEDELGSSYLALLPIGETPENMRNCDLFQFAQDLSFPAELRMKIHY
                     PRLKGQGGIGLKLNWLSERFKTEHKELVQNDEEPSERLLTVRGLVKHLKQRVDNGQPV
                     VDWIACFIVYGQTVEEVRQNSATVIQQLHTIIHIHRAKNDQRELFYKCLLGQPLGRQL
                     HWKHRTTVEAVGEWLFSAVSELGMESGWYIGRQDTLGDGGSRGEKTPLEELIYASNRF
                     VFLNLLAIAEGIKGALFDAPHVAVTGKTGKGKTFLVGLLFLYSSFMNVQSLFVDPKGE
                     KRKWFTKLIQDPYYQKHYPLFVEHLQKMSYVTLDATNPRNYGVLDPIVCLSRVDAKQV
                     AQDMIDELSPLGTNHLLKGAVLKGIQEVLVQKEAGQQVGLMHVVDYLEQMEQKEVREY
                     GEFLRLTVEDSILRLGFSYGENPGLDFNAKTTILEIQDLKLPNDNVRPELYTDADRKS
                     LCLMISLGRFCEMFGKRDSSKKTAIYFTEAWVFNNSNAGRSIIAAMARVGRSQMNQLV
                     LDTQFIGDLGSDKEKGNFGVVFAFDEDSEREKILNHLRLEVNEANLAEMSHMIKGQCW
                     MLDPYGRVGKLNVHSLFEEMTAALQTTEKTSHSQVEEQDTLIMQ"
     gene            37865..40075
                     /locus_tag="IXR40_000673"
     CDS             37865..40075
                     /locus_tag="IXR40_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360544.1"
                     /translation="MAYIKHKEKKWCVLFFLTIGFGLLFVGGLVYAAEKQVDQSIYEI
                     GKFHIDTFSSYLSDSEFSLGKMLFGANGTDFLKMMTNMFFSLSKLIWQGLDFVIEKLY
                     EGAAMNELIHQFFTFSDTIYSKIYDPIGAGIVVLYVLYLFTLRIFRGKHYAKMVFIRF
                     LFVVIFSMVWFGYGSNVPSKGEAFTKGLNDLSVEVEGFIFSATNSLDELATKDVNGVL
                     VPTTQKEAIQKVRQLYYKAAVVDPYILLNYGTTNLEELYQAEIEPQEFLAKEASSEEL
                     SDIETKVTTAAGEDRGKKKAYRVYIQPTKAVYKAVVGSMVPLLNLSIGLPLVVIGMIR
                     FIFQMLVLCLLLVIPFSLLASFVPVFDYMLMNTLKSFLGLMFQKSFYSVIILVAFLIY
                     NIVDDLIPMNTVFGFLGNMFVKALLSILLIVKRKDLLKKLGLGAADQTINNTKNIASH
                     SLSQMKQLPGQLSTAGQNLAIKGAGLAGNVYRATNPLASAAIHGFQKFQQKRTPQESV
                     KGRQVVNPFELGGRSNQALPYSGRHVRYHGVEPEMSSTKSKTEWNSGLSNGLIPNSSM
                     NSVRPKQQVQSLAQLSKQQGNNQRKPLLNKGIAFVGQSIPLPSGKVPVPQLTAAGSLS
                     QQIRQVKNQAKNGSYPAMQQLLNQYSVPNSSVATLSGNRSVQQPGQRSSESKPSISAP
                     KSLQPAFSSLDKPTEQSEKIEKDPKTLPILDAKPGTDFTLPKGRTVQKPLSKKG"
     gene            40083..41174
                     /locus_tag="IXR40_000674"
     CDS             40083..41174
                     /locus_tag="IXR40_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HAQ4360545.1"
                     /translation="MKKGCLGCLLFFILPFFLLPFFFSGELSEHGGEATGLAVAFNGE
                     YTEGLPIFSEIKGRGPITDEHAQAAVGAAVKYQLLPSVILSQLGYESAYGQSQSGRND
                     TNFFGITWFPGCPYPQGSARGIGGSEGGFYMKFPNLKACYDYYGFMVASQSNFNQCVG
                     NKDPGSCLLILGRGGYAAAGITEGSPYYRGAMSIITSYNLTEYDTFAIKHWNSLPTKK
                     TSLIAGKSKGNAKVLDRIIGRSVNNGECYGGTAWYVSQLGGPQLMGSGHMFAMLIGED
                     YNWTTYGWQVIMNPKPSDLQAGDVVNWQAGGALSPGIYGHTGIITDVSYGGQHFSSVE
                     QNAEQGRIMARYQRTYNQTKIRSLVRKVK"
     gene            41195..41737
                     /locus_tag="IXR40_000675"
     CDS             41195..41737
                     /locus_tag="IXR40_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360546.1"
                     /translation="MKKGIILVFSWLCLIGLTGCHWFSSEKQKTQLRTTEETIEAVKE
                     TSGTLQSTESNSQIGSLEDETAQQMQIDEMTKNFLKDFARKWSNFTDVYKRNQAVRDY
                     MTDRCIKDNSIDVDPHVQMKTTGKLYQVTQDIENPDQYLLFGEETMNKVTQFVLLQLK
                     VDQEAQKIDAIKIYYVRSAY"
     gene            41959..42189
                     /locus_tag="IXR40_000676"
     CDS             41959..42189
                     /locus_tag="IXR40_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003653123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360547.1"
                     /translation="MCIGFVGVGLFVSTESASAAEWYNPIWYNPNIECQKGYPYGPTN
                     LKNGKCRVNWNGVVDSVITGSMDSALHGFTGH"
     gene            42203..42535
                     /locus_tag="IXR40_000677"
     CDS             42203..42535
                     /locus_tag="IXR40_000677"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360548.1"
                     /translation="MSEEKKEIVESLVALKDSLSKIEYVDRQEIQKLIDDTIIEIQDA
                     RCEGIKISVALSKVIEKMNRSLAFNGLKLDRQTSLIWDHLKDLYDKSKRSERTAVSIL
                     KGLWGMNS"
     gene            42580..43128
                     /locus_tag="IXR40_000678"
     CDS             42580..43128
                     /locus_tag="IXR40_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAQ4360549.1"
                     /translation="MKRIIKIFGVLGVFLLGLSTFVSTGTSVYATEKVNTVDLEIKNK
                     LVDELTFYFDTVGFLDEHGVYHIKDFGAIRERISQDNEQGRAARVFYEHIIVPRMEKV
                     DWKRYAGCVAINSLPGGGVAWAIGTQGDFIEALKAFNFEKAADLLLKIAEKQLGKAAA
                     KELAKVNIVAGIAAAAASCALE"
     gene            43135..>43395
                     /locus_tag="IXR40_000679"
     CDS             43135..>43395
                     /locus_tag="IXR40_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360550.1"
                     /translation="MKSLEQEHMAFKQAMFKENIYLNHNYIRVSKACSPVLNMLGGGN
                     GLYHLLFVDVCWLIFLPDELVIVNEKITSKNEVFNYSLTRINY"
BASE COUNT        14811 a         6921 c         9287 g        12376 t
ORIGIN      
        1 tcatctcgat cattgtgaac tgatctcaca cttgcgaatg gaaggaaaat atcaatttac
       61 gaaagaaaat acaccaatcg ataaacatac gcatgtactt ttcttttttg aggatggaag
      121 ccaacttcgc tacaacgatg tacgaaaatt tggtcgtatg acaatcgtcg aaaaaggagc
      181 aagtgcaact taccgaggaa tcatgaaatt gggacctgag cctttgccag atagcttctt
      241 attagcagat ttcgcaaatg gactgaaaaa gtcccacaaa gcaatcaagc cattgctgct
      301 agaccaacgt ctagtgactg gtctaggtaa tatttatgta gatgaagcat tatgggaagc
      361 gaagatccat ccagaacaac cggcgaacac actgcgcccc aaagaggtag aacaattacg
      421 tctatcgatc attgatgttt tggatcgtgc aatagaagcc ggaggtacca cgattcgcag
      481 ttatttgaat gcattaggag aatcaggcgg atttcaagta gcactgcatg tctatcagca
      541 aactggcaaa ccatgtatac gttgtggaac gccgatcgtg aaaacaaaag tggcacaaag
      601 ggggacgcac tattgtccga attgtcaaag gctaaaaatc gcaaagtagg atttgtttta
      661 ggtttgacgg gtggaatagc taccggtaaa agtacggcag ccaaagtctt tcagtctcat
      721 ggatttcctt tgatcgatgg cgatgtgatt gccagagaaa ctgttgagcc tggaacgctt
      781 gctctgagga aaattgtatc agtgtttggc caagaggtat tgcagcctga tgggcaacta
      841 gatcgaggga aacttgggat gattgttttt ccatcaaaga aaaaacggca aaaacttgat
      901 cagctattag atccgtttat ccgaaaagcg ataaaagatc aaatcgcctc tctaagttcc
      961 aatcatcctt tagtaattgt agatatccca ttgctctacg aaggtcatta tgaccactat
     1021 atggatgcag tagctgtcgt ttatactacg ccagaaactc agcttcagcg tttgatgaaa
     1081 cgtaatcaac tgacgctaga acaagcgcag cagagaatta gtagtcaact tccaatcgaa
     1141 gaaaaaaagc agcgtgcgga tattttgttc gacaacaatg gaacaaaaga aaaacttgtg
     1201 ggacaaatcg aaaattggct ttttgctaat cgctttcttt gagtatctgt gtcaattttg
     1261 ctatcctgag tatatagaaa gtgagggata gcgatgggat cattaaaaaa tcaaaaggat
     1321 aaagtcgtag gtaacgcaaa agaaaaaatc ggcgagatgc tcaataaaga aaatctaatc
     1381 gatgaaggtc gtacgcaatc agaaacagca gaagaaaaag aaaagcagta ccaagcaaga
     1441 atcgatgaaa tagaagacca gcaggcagaa gaagaagcga agcggcaaga tttgactcaa
     1501 gaacgaaaaa atccgacacc tgatcgtagt aaaacaccgc tcccagaaag tgaccacatt
     1561 cccgatgagc aaaaaatcga ggaacagcga atgaaacact atacaggaat cgaagagaag
     1621 ttataaaata gtaaaaaatc gagatgtgac ttgaagcaga tgagaaggtg ttcatctgct
     1681 tcaagttttt tgtgctagat gactaaatca gcttttgtgt aagttatttc tcagtaatca
     1741 aggtgatcag tattggaaaa ttgaaattta gtaaggacag gggacacaat tacgcatgaa
     1801 agtagaaaaa attgttctta tatccgtgtt ttttgggtag gacagtcgcg tttgtgattt
     1861 gtttcgtgtt ataatacaac tagttgtaaa gaaagacaca tcctttatat aaaatgcgat
     1921 gcaagaggtg agacaaaatg agatgtccca gatgtcaaca taataattca cgagtaatcg
     1981 acagccgtca agcagatgat ggacgtgcga tccgtcgccg tcgcgaatgt gagaattgtt
     2041 cgttccgatt cactacattt gaacgaattg aagctgctcc gttattagta atcaagaaaa
     2101 acggggaacg cgaagagttc aatcgcgata aaattttaag aggactcatc cgttcagcag
     2161 aaaaaagacc tgtagctatg gaacaaatgg aacaaatcgt caaccatgtc gaaaaccgcg
     2221 tacgcagtct cggagaaaac gaagtatcga cgaatctaat tggtgaatat gtgatggaag
     2281 atttagttga tttagacgaa atcgcttata ttcgttttgc aagtgtttat cgccagttca
     2341 aagatatgtc tgttttctta aaagagttgc aagatatcgt ggataaagca aaagaaaata
     2401 ataaagagaa taataaagaa aacaattaag aaacaaaaag gaggcatttc cttggaaaat
     2461 gcttggaaag agcttcaacc aaaaaatatt taccaaggaa gaaaagcggc tccgctgaga
     2521 gaagacagca agaacgcctt gctgtatctt tatcagccac taatcggcgg agaagccttg
     2581 agtatctatt tcaccctgtt atcagaaatc tctcaagaat ctggcaaagg tcctgaaggg
     2641 atgcatgcag atctgcttag tagtctaggc tgcggtatcc cgcaatttta tgatgcaaga
     2701 aaaaagctag aaggaatcgg cttactggat gtttatttta aagaagatag tgatctggga
     2761 cctcgtttta tttatgagct gttagaacca ctcattccta aagcattttt caaagactct
     2821 gttctggctt ttcttcttct ggaaaaagtt ggtgaacgac gattccagaa gcttacccaa
     2881 ttctttgaac ctaaaaggca tacagcagag ggatatcaaa aaatcacaaa aaaattttta
     2941 gatgtttatc gcttcaatga agcagtgtac gctgctaatc aagaaaacat cgaatcgctg
     3001 aataaatctt ttgaagaatc tgaatcagta gcattacttg aagcagattc gacattcgat
     3061 tggcagtttt tgaatgattg gctggcaaaa aaacatattg caagtcttga tgatccaatc
     3121 atcaaacaag tcgacatgta tcatcagctt tacggtttcg atgaattgac acttggcgaa
     3181 ctgatcagtc aatcttatga ctttagtgaa caaaaagtat ctgaaaaaga actgcaaaaa
     3241 gccattttgg caatgcagag acgtccggtg aagcaaacaa aagaaacagt tgcggtttct
     3301 gaaaacagta atgaaccctc gtcaaacgaa catttgacaa acgcagcgct tcagctgata
     3361 aaagaagcac agagcattcc accgatgaaa tatctggaag caatcaagtc agaaaaaggc
     3421 ggatatgttt ctaaacaaga aaactggtta ctgcaagatc ttgtttctca atcaggtctt
     3481 tccagtagcg tgatcaatgt tttgctgaat tatgtactag tgatcaagaa taatgctagc
     3541 ttaaatgcca gttatgtaaa tacagtggca aatgaatggg cacaaaagaa aatcgccaca
     3601 gcagaagaag cgatccagca cattcggcaa ataagtaatc aagcaaaaca atcaaaacaa
     3661 aagaagcaaa caaattatca aactggcaag cgaaatgttc gacgggaaaa gcttcctgat
     3721 tgggtcaacc agccaaaaga tgaaaaacag atcagcagcg agaaaaaagc agagattgac
     3781 cgccgtttta aagaatacct ggcaaaaaag gagggtgata tctagtggaa gacgtaggca
     3841 aagaattgaa gaggatcatc agcaaacgca attatcaaga aaagtatgct gaaatgatcg
     3901 ctgaagtctt aaatgatgcg gatgttcaag cttttctaag cgcacaccaa gaagaattga
     3961 cacaagcgga tattgaaaaa agttacgcta aattgtatga attcgtgcaa gaaaagcgta
     4021 aatatcaaaa aaacgatcca acgatgatcg ctcccggcta tgagccgaag ctgacgttga
     4081 attttcatta tgtggatgtc acttatgtac caacggaagc attgttagca cggcaaagac
     4141 aagaagaaat cagaagccga gtaaaagcaa tggatatgcc aaaagatatt caatcggctt
     4201 cttttgaaaa ctttgaacgt acagatggac gaggatatgc gagcttagaa gccctagatt
     4261 ttgtagagaa atatactgct gatccaaaag ggtatcataa aggactgtat ctagtaggaa
     4321 gttttggtat tggaaaaaca tatttattag gagcaacagc gagagaatta gcgattgctg
     4381 gattcaccac gacgctagtc cattttccga catttgccgt tgagatgaaa caggcaatcg
     4441 gaaaagatca agtggcagaa aagttagatg cagtgaaacg ttcacctatt ttgatgatcg
     4501 atgacattgg tgcagatgcg atgagtagtt ggatacgaga cgaagtattc ggtgttatcc
     4561 ttcaatatcg gatgcaggaa cagttaccaa ccttcttctc atcgaatttt acaatggatg
     4621 aattggaaca gcatttgtcc gtcactcaac gtggagatga agagccgcta aaagcgaaac
     4681 ggataatgga acgcatacgt tatttgacaa aagaaatcga aatgactggt cgcaaccgac
     4741 gcaatggttg aacagttgac aagtccaact gacatttgac ctagtagtaa aagcaggtca
     4801 gcgaatcatt atatggacag aaatgaccgg agacaatcac cgcaacaagt aatgcagaaa
     4861 cttaaacgga ggatttttta tgagggctat tttttctagt atatctgtag ttggtctatt
     4921 ttttctttta gcaggctgcg gtagcgcaga tagcaacaca ggttctgttg attcgattga
     4981 tgcgggtcaa acagtaaaaa caagcagtac gaaaacggag agacaaagca tatttgtcgg
     5041 aacgattgaa agtatcactc aagtagaagc agaagaagaa acgcttcagt tgaaactcgt
     5101 cgatgtcatg gccaaagaag atccagcgaa tatgggaacg tcattcagca atgacggagt
     5161 gatcttaaat gctactgctg aaaaaataag cgtggacata aatgaattga aaatcggtga
     5221 caaagtccaa tttacattag ttgagatgcc gatcatgacg atgtctatcc caccgcaagt
     5281 tcctggagat tcgattattg atgtttcatt gaacaaataa ccaataacat tttttcaaaa
     5341 ataagaaaat gttgttttat agaacgaaaa ggtatatttt ttaaggagat atgggaattt
     5401 ttttattcct agtctcctta ttttatttgg aaaatgctat aattatctag aaggagtgaa
     5461 gctatgaacc atttagattt atctcagcgc ttagccgcag tgggtgactt tgtccctgaa
     5521 tccgctcgtt tagcagacat tggatcagat cacgcttact tacccgttgc attgatatta
     5581 agaggaaaaa tcgaatatgc agttgctggt gaagtcgttc aaggtcctta tgaatcagca
     5641 cgtaagcaag tcaaaaaaga tggattagaa gaccgtatca ccgtacgcct tgcaaatggt
     5701 ctagatgcta tccagccaca agatggtatt acagctgtca cgattgcggg tatgggaggt
     5761 tcactgatcc gagatatcct agaagctggc aagttgaatc aacgcttaag cggacaagaa
     5821 cgtttgatcc ttcagccaaa catcggagag cgtacattac gatcttggct gcaagaaaat
     5881 cagtataaaa tccaatcaga aaaaatactt gaagaaaata aaaaaatata tgaaatcatt
     5941 gtagccgaaa aagaacaaaa accagttact tacaatgaaa tggagctgat gttcgggcca
     6001 tttctgcttg aagagaaaag tgagatcttc aaatcaaaat ggacaagaga gcttcaacaa
     6061 agaaaagcta tccgtgaaca gctcaaacaa gcagctaatc aagaggcacg tcaaaaacaa
     6121 atcgagcagg aaatccaaat gattgaggag gttttaaagc catgacaatc agcggacgca
     6181 ctttcatcca aaagtttgaa agctattgtc ctcagtggct agctgaagaa ggagacccag
     6241 tcggactgca tatcggaaca ttggataagc caatccaacg agtaatgatg acattagacg
     6301 ttcgtccaga agtggtcgaa gaagcaatca agaaaaaaat cgatttgctg attgctaaac
     6361 atcctccaat ctttcgtcct gtaaaacggc tggttactga tcagccacaa gaaaaaatgt
     6421 atgcagattt gttgaaacat gatattgccg tctatgcagc acacacgaac atggatatta
     6481 tttgggatgg actgaatgac tggttttgtg aacttctcgg tattgaagtg gagagttatt
     6541 tagtaaagac tcatgagatt cattataaaa aactggccgt ttatgtacct gtggatcatg
     6601 cacagaaaat gcgtgaagta ttagctgcag ctggtgctgg tacacaaggt gattataccg
     6661 gtacaagttt tacctcgatt ggacacggtc gatttactcc ggaagctggt gcacaaccag
     6721 cgattgggaa agtagggaag acagaacaag ttcaagaggc aaaagttgag gttattttgc
     6781 cggaaactat cgaaaaacaa gtgattcaag ccatgcggtc agctcatcct tatgaggaac
     6841 ctgcttatga tcttttcgct atagatgaac cagtcgaaat gtttgggtta ggacgagtag
     6901 gtgaattgcc gcaagaaatt tctatagagg catttgtaga acaagtaaaa gaagcgttcc
     6961 aactagatgg actgagaata gtccagccaa aaaatgcaaa atcctctgtg aagcgcattg
     7021 cgatttgcgg tggaagcggt gaaaaatttt atccgcaagc aatcgcccaa agagcagatg
     7081 tctatatcac gggagatatc tattatcata cggctcatga tatgcaaagc gctgggttga
     7141 ttgcaattga tcccggtcat tatattgaat cgttatgcaa gcaacgattt atcgagaaat
     7201 ttgaatcttg gaaacaagaa gaaaattggg atattaactt tttcgtttct gaaacaaata
     7261 caaacccatt tcaatttaat taaaaggaga gaatactatg tacgaaaatc ttttgccacg
     7321 ttttttacga tatgtcaaaa cagaaacacg ctccgatgca acaagcaaaa cgactccatc
     7381 gactcagaca caagttgctt ttgcgcaaga attgaaaaaa gaattagaag agttaggctt
     7441 agctgatgtt ttctataatg aagataacgg attcgttatg ggaacattac caagcaatgt
     7501 tgatcatgaa gtgcgttcca ttggatttat ttcccacatg gatacagcag attttaatgc
     7561 agtaggagtc aatccacaaa tcattgaaaa ctatgatggc gagtctacga tcgtactaga
     7621 tgcggaagaa cgctatacat tgaatacaaa agattttcca aatttgaaaa attatgaagg
     7681 ccacacattg atcacaacag atggcagtac attactggga gcagatgaca aatcagggat
     7741 tgcggaaatc atgactgcaa tggagatctt gatcaataat ccttctatcc ctcacggtac
     7801 catcaaagtg gcttttggtc ctgatgaaga aatcggtgtc ggagcggata aattcgatgt
     7861 tgagcaattc gatgtagatt ttgcttatac agtcgatggt ggtcctttag gtgagttgca
     7921 gtatgaaacg tttagtgctg ctcaagcaaa tattacgatc caagggaaaa atgtacatcc
     7981 agggacggca aaagatacaa tgatcaatgc tctacagtta gcaatcgatt ttcataatca
     8041 gcttccagcc gatgaagttc cagaaaaaac ggaaggatac gaaggtttct tccatttgat
     8101 ggcattggat gggaatcctg aagaagcttc tatgagttat atcattcgcg atcatgatcg
     8161 tgaaaaattc gaagcacgca aagcacaaat cacacatatc caagaagagt tgaatcagcg
     8221 atttgatcaa gaacgaatca aagtagatat gtatgatcaa tattacaaca tgaaagaaat
     8281 cattgaaaaa gatatgagca tcgtggaatt agcgaaacaa gcaatgatcg agcttggtat
     8341 ctctccagtg atcgaaccag ttcgtggagg aacagatggt tcaaaaatct cttacatggg
     8401 tattccgacg ccaaatctat ttgccggagg agaaaatatg cacggacgat tcgaatttgt
     8461 ttctttacaa gtaatggaaa aagcaacaga cgtgattgta aaaattgcag aattgaacac
     8521 aaagagttaa aatcgaaaaa gaacagctta tgacaaggcg ttcgtcccaa tgatggaatg
     8581 tcatctgtct aaggctaaag ggcaggacaa tggaattggt tgtcccgccc tcttttttga
     8641 agagtaaata ggaggtaaag aatggaaaag ctgctagttt tttataacaa aagttcaggg
     8701 aaagatgagg gtgagaaatt agcacgctgg tttcaagatt atgtaaaaga aaagcagcca
     8761 gaattatatg tagaactagc tgaaactggc ccatcgattg atgatgcgga attagtcaag
     8821 aaagcagaag ccatagaagc tgatacttta gtaattatag gtggagacgg cacgattcat
     8881 catatcgtcc aagcgttcca aaaaacatta tctcaatacc atgtcggatt acttccaggt
     8941 ggaactgtca acaaccttgc acgtgttctt gagattcccc tcaaaaaaga agaagctgct
     9001 gacgtgatcc tggaaggcaa tgtacggaaa atagactatg gtcaagtcaa tgatgaagtc
     9061 attatctcta cactgacaat cggaatctta gcagatacag cagtttggat cagtcaagaa
     9121 gaaaaacagc gttacggctc gtggatcttt atcaagaagt tttttaagtt attgctgaag
     9181 aagaaaaaat atcatttgga tttagaaaca gacgaggagc attggaaagg aaaatcccaa
     9241 ctgttgacag tcacgatgtc taactccgtg ggcggtttta caaattttga cgactcagcg
     9301 accctagatg atggaaaatt tcatgtaacg atcgtacctt ccttagatat tttccgattt
     9361 attttttatt tgcctagaat catgagaggc aaattctata cgatccccgg cattacttat
     9421 ttcacagcca aacgcatgaa aatccaagcg caggaaaaat ctgtgggcac tcgaacggat
     9481 ggagacacga cagatgatct tccagttgaa ttatctgttg tatcaaaagg attaacagtt
     9541 tattcaccaa agaaagaaga aaaagcttag aaatagtagt taacagaaag ttggaagaag
     9601 agtaatggat gtattgttac acaatccttt gtggttttac cttttcattg tgaattttta
     9661 cttattttgt ctgatggggt atgataaaca tcaggctaga actagcggct ggcgtgttcc
     9721 tgagaataat ttgatatttg tcagcctgtt aggcggtggt ttgggaggat tgatctctcg
     9781 aaaagttttc catcataaaa ctcggaaaaa gaagtttact ataggattcg ctgcaggtgt
     9841 acttgttgat ttgattctca tttatttttt ccattaagga gcaggagatg tcgtctaaag
     9901 gaacgaaaac taaaatcatt ctgaatctgc ttttgctgat tgtgattttt gccattattt
     9961 attatttaat caatcaatca tttgcagata tctttgccga attgctgtct accagtgttg
    10021 ttgttttggc agcggctgtt atattaggga cagtttacca aatcgctgaa gggcgctcaa
    10081 tcaaagaaat tgctgaacct ttcgcgccga attttacaac gaaagatggg ttcttgacct
    10141 ctagctatat tgcgttttac cgaatcgttt cgtttggtac aggaacgctg atctcggaga
    10201 tttattttta taacaaaaaa ggaatgaagc tatcccaggg agcaggggtg acagcactcc
    10261 atatgattat gtacaaactg gcagtgatca cttatgcatt agctggcttg gtcatccaat
    10321 tctctctttt ttattctaat ggtccatcaa tgatctggtt tatcatcgct ggtatccttt
    10381 tgacgatcgt gattgttgcc tttttattgg cgatgtccgt cagcttgaat gttcaaatat
    10441 tttttgtcag cttatcgaat aagttattta aaagtgagcg tttgcggaaa tgggtggata
    10501 catgcaatca gcagatctac tctttaaggg aaacggtcca aaccattatc caagacagga
    10561 ctgcgctatt gcggatttat ctatggaata tgttaaaact tgtattttgg tatgtacttc
    10621 cttatttgat tctgattgaa aaccatccta aaatagattt tctactgacc atttcgttta
    10681 tcagctttgc agtagtgctt tcaggggtta ttcctacgcc tgctggtatt ggttcctttg
    10741 aatttgtcta tttgttatta ttcagaccag ttgttggaac agttgacgca gtttcttcgc
    10801 ttttactgta tcgtttcagt tcctttatct tgccatttct ctatggattt gtgtatgtga
    10861 ttgctgaacg gcgaagagtg atcaaagaag aaataataga agtaaaaaaa gagaataaag
    10921 aaaatcaagg gtaggtcttt tataagatct acccttttta tcaaatcaaa gaaaaacgtt
    10981 atggataaga taattttacg tttgtttggc tcttttttta tatacataca atcaattttg
    11041 tttttttaag atttatataa gtcgagaaaa aaagtcaaaa aactatgtgt atattttgac
    11101 caaaattgac caaagcgata taatagtttt tgtaaagatc aaagaaataa gtgatcttac
    11161 ctttaattag gagggtatac ctgtatgaat attgagaaaa tgactacgac gcttcaagaa
    11221 gcgattgctg aagctcaaca gattgcggtc actcgaaaac atcaagatat cgacattgcc
    11281 catgtatgga aaatcttttt acaatctaat cattttggtc gaaatttcta tacggatgcc
    11341 ggattggatg tcgaatcttt tgaacatgaa attgatcgtc tactggatga gtatccagtt
    11401 gtttctggtg gaaacgtcca atatggacaa aacctcagcc agaatttctt tcgattattg
    11461 aatgaagcag accaaatacg tgaaagcttc ggcgacgagt ttctttcaac ggaagtcgtt
    11521 attttagcgt tgatgaaatt aaaaaattat ccgttaactg tttatttgaa taaaaacgga
    11581 ttatctgaaa aagaattgcg taaaaacatc gaagagatga gaggaggaga aagagtgacc
    11641 tcacaaaacc aagaagaaca atacaaagca ttagaaaaat acggcgttga tttagtacag
    11701 caagtcaaaa gcggaaaaat ggatccaatc atcggtcgtg atgaagaaat ccgtgatgtc
    11761 atccgtattc tttcacgaaa aacaaaaaat aatcctgttc tgataggaga acccggtgta
    11821 gggaaaacgg caatcgttga agggcttgct caacgtatcg tacgcaaaga tgtgcctgaa
    11881 aatttaaaag ataaaacgat tttttcatta gatatgggtg cattgatcgc tggagcaaaa
    11941 ttccgtggtg aatttgaaga aagactaaaa gcagtcttga aagaagtcaa aaaaagtgat
    12001 ggacgtatcc tcttgttcat cgatgaaatc cacaatatcg taggggcagg aaaaacagaa
    12061 ggaagtatgg atgccggaaa tctgttgaaa ccaatgcttg ctcgcggtga attacatttg
    12121 atcggtgcca caactttaga tgagtaccgt caatatatgg aaaaagacaa agcgttggaa
    12181 cgtcgctttc aaaaggtatt agtcaaagaa ccaacagtgg aagatacgat cagtattctg
    12241 cgtggattaa aagaacgttt tgagatccac catggtgtta acatccatga caacgcatta
    12301 gtagcagcag ctactttatc tgaccgttat attactgatc ggttcttacc ggacaaagca
    12361 atcgatttga tcgatgaagc cagtgcaacg attcgggtag aaatgaactc tatgccaacg
    12421 gaattagatc aagttactag acgtttgatg cagttggaaa tcgaagaagc tgcactgaaa
    12481 aaagaatcag atgatgcaag taaaaaacgc ttgaaaaatt tgcaagaaga attagctgaa
    12541 cttcgtgaag aagcaaatgc gatgaagatg cagtgggaaa cagaaaaaga agaagtcaat
    12601 tctgtttcag caaaacgtgc tgaaatcgat aaagcaaaac acgaattaga agatgcagaa
    12661 aataactatg atttagaacg cgctgctgta ttgcgtcatg gtacgatacc tcaattagaa
    12721 aaagaattga aggaattaga agctaaagca aaagacagcg agattaagat ggttcaagag
    12781 tccgttaccg aaaatgagat tgctcaagtc gttggcagat taacgggtat ccccgtaacg
    12841 aaacttgtag aaggtgaacg agaaaaacta attaaattga atgaaacact tcataaacga
    12901 gtgattggtc aagatgaagc agttgatgcg gtcagtgacg cggtaattcg ttcacgggct
    12961 ggattgcaag acccaaatcg tcctctaggt tctttccttt tcctaggacc aactggtgtc
    13021 ggaaaaaccg aattagcgaa agcgttagct gagaacttgt ttgactcaga agatcatatg
    13081 gtacggatcg atatgagtga atatatggaa aaacatgctg tgtctcgtct agtcggagct
    13141 cctccaggct atgtaggtta cgaagaaggt ggtcaattaa cggaagctgt cagacgaaat
    13201 ccttatacaa tcgtcttgtt ggatgaaatc gaaaaagcgc atcccgatgt cttcaatatc
    13261 ttgttacaag tcctagatga cggacgcttg actgattcaa aagggcgagt agtagatttc
    13321 aaaaatacgg ttctgatcat gaccagcaat atcggttcac agttactgct ggaaggcgtg
    13381 actgctgatg gaacgattcc agaagcagtg gctgaacaag tcaacacgct attacgtgga
    13441 aacttcaaac cagaattctt gaaccgaatc gacgacacga ttttatttac accattgagc
    13501 ctagacaacg tgaaaggaat cgttgacaaa atggtggcgc aattggcaca acgtctggaa
    13561 catcaagaaa tcctgctgac aatcagtgat gaagccaaaa cgtggattgc tgaaaatgct
    13621 tatgaaccag catatggtgc aagaccattg aaacgattta tcactaagga agtagaaaca
    13681 ccactagcta aagaaatcgt tgcaggacat gttatgccta aatcaaaagt aacgattact
    13741 ttacttgatg gacaacttca tttcaaaaca gaagagctag aagaaatcgt ctaatcttcc
    13801 attgagacta taaaagaaaa aaggggtctg acacaactag tgtcagacct ccttttttca
    13861 aataaacagt gttccagaag tagtttcttc gaaaaataag ccgaaatttc ttgaagctgc
    13921 ccgcttctgt cacaacctct tttattaggt atttttcact ttttctaatt tataactttc
    13981 aaagtaacgc tcatcttttt tactttgaga ccatgcaaac aatcccatta aggcagcacc
    14041 tatcgtattt gtcagcaagt cgcccatcgt atccatcaat gctgctcgtc cgacaaacag
    14101 tgtgccatca gaagcagcaa aacgttgaag attcatgcct aagaactggt cgcataagaa
    14161 ttcccagaac tcccaaaaca cgccgcaaag tccagcaaac gcaaagccga ataagaggaa
    14221 caaccaagga ctggtttttg atatctcagc atctttcatc aagtaaccaa tcaatccata
    14281 gccaagagct gtcaggacca ttggactcac cgcatgtaag attttgtccc aaaaagagat
    14341 gatactgatc aaatgcatcc ctgtgcctaa aaagacagag atgaacaaga aaaaccagta
    14401 aaacaaaacg attgctgctg gtattttaag tttgaaaact ttcaaaatga cttgtggcat
    14461 gaaaatcaat gcaatcccta ataaagattc cacgataaat gtgattcctt gagaagtcga
    14521 atatttttgt gtgataaatt cataaaaatt atagcagaca acgaatacac caaaagcaag
    14581 taaagctatt tgcacctttt tgatttcttt aatcactgaa agtccctcca tctaaaaatc
    14641 tttttacttc tgaaagcaac tcaatttctg aagaaaccac ttttccgttc aatttgatca
    14701 aacctattgt atataagttc aggtagtgaa attgattttc agctgtttct tgtagtgcag
    14761 cgattttttt cgggtgggtt ccgccttgct gtcgagtatc agtatataag ccgatcactg
    14821 ggatgccttt cgcataagcc acaccgattt ccgatgctac cccggcatcg atcgtcagcc
    14881 catctagtaa agcaatcatt aaatcactag ccaacacttt ttctgtgtca gcaagagcaa
    14941 tcattcgact gtctgcataa gcagttttgt cattgattgc ttcattttct tgaggaagat
    15001 agatcgaaag ctcagaagag agctctctga tttctttaac taactgttgg ttatataaca
    15061 aatcactttt agcaaacatt ggtgcggcaa aataaatttt catctaaaca tcatcctttt
    15121 tatcaaaaat aatcgctaaa gtaagcttcc atgtttggaa tgatacgctc tagtgacttc
    15181 agtgtttctt catctgtttc taaccgttcg attcttgcca aataagaagc acggcgataa
    15241 ttcatcatca agcaagtcaa tgtttggata tccagtcgaa cggattttcc tataggttca
    15301 tttaagacac ggacttgtcc ctgttcatcc catgttaaag cgaagacacc attattccaa
    15361 ggagcgacag gatcttcaat gatgaaatga aaagcatcag ctgttccaac aaacggaaac
    15421 cgttgaagga attcttttac atcaacgatc cgagccataa aatatggttc gatctgctct
    15481 ttgatctgac tatcttcaat caaaaatgct aaaggctcat ttttataaat atctccatgt
    15541 acccagtaga tcatggaaaa atgtgcggaa ataaagttcc ataagccatt tcgagcttct
    15601 tgatcaagat agaacatttc ttttacgtga aatatttctt cagctaccca gtagaacaga
    15661 acacctcttg gttcatggtt gctatcgtag tagacagcgg ctgtgcgctc atcttcattt
    15721 tcgaaacgcc aatactcttc ccaatgaaaa tcactgcgga ataaagcacc atggttttgt
    15781 tgggcaaatt tgtcataaac ggaaaatacg tctggatgat caactggtaa tcgctcaacc
    15841 ataccactta ctgggatttg tttaggtagc tgtgtatctc tgattttaaa ggaaagttta
    15901 tcagacatga tttcccatcc tttacgccga tagtagggga tactgtaagg atacaaataa
    15961 gagatccatt gcttattctt gcgcatatta tccaatgcaa cgataattag atcttgcatc
    16021 aatccatggt tagcatattc tggataagtt ccaactccag tcacaccacc cattttataa
    16081 cgtgcaccgt gaatattgac ttcacaagga tagatagcga tttgagagat cagtttattt
    16141 tcgtggaacc atccgaacac tttcgatact tccaaaatcg gttttttgga acggataaaa
    16201 gctcgtttat tctcaaaccc gctttcctcg atgtctgctt cagtcacttg gaacacatag
    16261 gaaagcaatt cattgaattg atcgatatgt tcttgagtga ccggttttaa ttcaagattt
    16321 tctctaaaat ctttttgatc cattttttca tctccattta ttagcttgat aacagtatag
    16381 caaaattcta caaaaaaaac ttctatagct gactaattaa aaactcttta aattactgct
    16441 tttcgttggt ataatggaaa gtgctgatta tatgaaaaga ggagacgcta tggatataaa
    16501 gaaaatgaaa gaacgccaag agcagattcg taatttttcg atcatcgctc atatcgacca
    16561 tgggaaatct acattggccg atcgtatttt agaaatgacg cacactgtga cgtctcgcga
    16621 aatgcaagat cagctgttag actcgatgga tttggaacgt gaacgtggaa tcacgattaa
    16681 attaaatgct gtagaactca attacacagc gaaaaatgga gaaacatata tctttcactt
    16741 gattgacacc ccagggcacg tcgacttcac ctatgaagtc tctcgaagcc ttgctgcctg
    16801 tgagggtgcc gttttagtgg tcgatgcagc acaaggaatc gaagcacaaa cattggccaa
    16861 tgtttattta gcgttagaca atgatttgga gatcctgcca gtcatcaata aaatcgacct
    16921 acccgcagca gatcccgaac gtgtccgtca agaaatcgaa gacgtaatcg gaatcgatgc
    16981 tagtgaagct gtattagcca gtgccaaatc agggattggg attgaagata ttctcgagca
    17041 gatcgtggaa tatgttcctg caccaagtgg agacttagat gcaccgctaa aagctttgat
    17101 ctttgactct atttatgata gttaccgcgg tgttgttcta aatgtccgga tcacggacgg
    17161 tatggtcaaa cccggagaca aaatcaaact gatgagtaat ggcaaaacat ttgatgttac
    17221 agaggtcggg gtcttctcgc caaaagcagt tgctagagac tttttgatgg tcggtgatgt
    17281 cggttatatc acagcaagta tcaaaactgt ccaagataca cgagtagggg atacagtaac
    17341 gttagcagac aatcctgccg ctgaagcttt accaggttac cgaaaaatga atccgatggt
    17401 ttattgtggt ctttatccaa ttgatacttc tcgttacaac gatttgcggg aagctttaga
    17461 aaaactgcaa ttgaatgatg ctgctttaca attcgaacca gaaacctctc aagcattagg
    17521 ttttgggttc cgctgtggat tcctcggact tcttcatatg gatgtcgtcc aagaacgctt
    17581 ggaacgggaa ttcaatctag aattgatcac gactgcacca tccgttattt accatgttaa
    17641 taaaacggat ggtacgactg ctacagtaga taacccggca gattttcctg aacctgtaac
    17701 gattcaggat gtagaagaac cattcgtcaa agcacagatc atggtcccaa atgattttgt
    17761 cggtgcagta atggaacttt ctcaacgaaa acggggagaa ttcattacga tggattattt
    17821 agatgattac cgagtaaatg tcgtctataa tattccgctt tctgaaattg tctttgactt
    17881 tttcgacaaa ttgaaatcaa gcacgaaagg ctatgcctca ttggattatg aaatgtctgg
    17941 ttatcaaaaa agcaagttag tgaagatgga catcttgctg aatggagaaa aagtcgatgc
    18001 attaagcttt atcgttcacc gagactttgc ctatgaacgt ggaaaagcaa tcgttgaaaa
    18061 actgaaaaaa ctaatcccac gccaacaatt tgaggtgcca atccaagcag ctattggaca
    18121 aaaaatcgtt gcccgttcag acatcaaagc cttgcgtaaa aacgtcttgg ctaaatgtta
    18181 tggtggagat gtttctcgta aacgtaaact cttagagaaa caaaaagaag ggaagaagcg
    18241 gatgaaacaa atcggctccg tcgaagttcc gcaagaagcc ttcatggccg ttctgaaaat
    18301 ggatgagcaa gatagtgtga aataacttat aatcaatcga aaaacctatt aaataaacct
    18361 ttttgagtag atgcaacact gaggattatc tgtataaaag attttaaact gtcatttggt
    18421 tatcacggcg atactaaaat taacaaaatt ggaatatttt tcttgaagat ttttagctgt
    18481 cagtatatga tgaaagcatc tcataggagg tgcttttttc atggttgata attcaagtgg
    18541 aagggttctt aaatctctaa gaaaagagaa aaaactatct caaaaaaagt tagctgattt
    18601 agcaggtatt tcacaaagta ctttagttaa atatgaaaaa gggtcaagaa aaatccctaa
    18661 agacgtagat aatactctaa gcaagattct gaatatagaa actctaataa aagatgagga
    18721 agataagatt gagattctca tcggtaaact aattgcatac agagatatga ataagttact
    18781 taacaaagag ttagctgata atataggaat tagtgaagta ttactcagtt atgtgttaaa
    18841 tagaaagaga aatccgtcaa aagaaatgca aaaaaaaatc gatatttttc tattaagtaa
    18901 tgaaaaagaa attttgaagg agattaatcg tgatagtgag atatttagtt tatcaaaaga
    18961 cgataaaatt gttatgggaa aaagaatacg agaagtccga aagaaccggg aagagacgct
    19021 tgaaaaattt ggtaaaaact ttaccatcta tacaggcaaa aatgttataa gtagatggga
    19081 aaaaggtatt aatattccag atattgaaaa actaatgaat attgcctatc ttggtaaggt
    19141 cactgttcct taccttatgt acggagaaga ttataagaat atacttccaa aagatgaaag
    19201 agttagcgat tttaaaaaga taaattcttt tagtatggga ttaaggatga ggaaaattag
    19261 gaaagattat tatctagaaa gggaggagtt tggaaagctt ttttctcctt caatttcaaa
    19321 atggtccata gataggtatg agaatggtag agatataccc aatactaatc gaattatcca
    19381 atatgcttat ataggaaatc tttctttaga atttttgatt tacgggatat aaaaatagtt
    19441 tacgtcgata cttattaagt tatcgacgtt ttttattata gaaaaaattt ataaaaggag
    19501 gtttcttgat atgataagaa acaaaaaggg tttgttgaaa gttgctttac tggcagcttt
    19561 tttctaagta actttttgac aagctcaatg gcaacacaag cggaagaagt aatacaagaa
    19621 ctaactgtta tgaataacag ctagataaaa tgggctatgt atgttatcca acaatttagt
    19681 aatcactaga agcctagcga aagttcgctt gataagttat agatgagtat tgatttgtag
    19741 tgtttccaaa tcaaaagggt acagagccac atgaaatatg ttgtcctctg cagcgtcagg
    19801 atgggaatcc ataccatgga gattcggaga tctgtgaggg aatacttacg tggttaatat
    19861 gtcagttgtg ttggacgtag taatggtcat agtgggtaga ttgactgaat tcttatatga
    19921 gaaaatgaaa ccaacaagaa gatagggtta tttatacaga attggggatc ttttctggaa
    19981 aagtaatcgg ataatgcgag attcgtacgg tcttttttaa atttctctaa aaaaaacggc
    20041 atcgaatggg ttgggtgatt gataagcaat gaatcataga ctgatataga ataaaaaatg
    20101 attctattta tctttttaca tctatcgttt tttcaagtag ccgcaaatta tatcagcatt
    20161 caacaatttt tgtatacaag ttctagtaaa aggatctgaa gaaaaagttg gttgttgtga
    20221 agataaaaaa agaatcaggt tttactgagt ttttcttcaa aatttgtgtt attaggttag
    20281 gacaaagata agaagaagta tgaagattta aaaaaggaat gaggaaaaga tagtaatttc
    20341 cgattattgg agttttttta tttataaaga agaagcgaat aagttgtgat tcctagattt
    20401 cgcgcgtgat taattaatga gcaaaaaatg cggaaagttt tagtgtttaa tacacgagga
    20461 caaagtttct taggtattga aggcacacgt gtaacggttg atgggtggtg tgattgtttc
    20521 gaggttggaa aacatgttga acttatggca tttactgagc taaaagataa gaacaacgtg
    20581 gaatttttcg agagtgatat tggttgggac gatcatgaag aagtttatgg aaaatttatt
    20641 ttgcggaagg gaaattctta tacgaatggg gaagcataag tagcgatttg ttagagatca
    20701 ttgataggat tgaaattgtc gggaatattt atgagaatct agagttattt gaggtgatag
    20761 aatgagtgat ggttttgaac aagtatcaat aattaaaaat caagttcggg agattcttag
    20821 aaaaaaaggc tatttggtag atagttattt tgaaggagat tacgaaacat gggtaggtgt
    20881 ctatgctcgt ccagagaata aacctaccta tttagatcct acgacgtcag aagatgccta
    20941 tttacaaaat aggtatcgag tagatggttt taagcaagac tttgcggagt ggtttgaatg
    21001 ggaaattgaa aacggagaag taaaagaaga ataagagtac ttgttgtatc aaaataagcc
    21061 agtagaacaa ccaaaccagt agctagtaat gacaataata ctgaggaatc ggatcattat
    21121 ggtatgattg atatttctct tccagaagat cttaagccag atcctgtaac aattggcaat
    21181 agtgtcatga tttttgattc attagatgaa gctatgtcat atggttggaa agaaattaag
    21241 gatgaaggta gtaattggta tggcatgaga tttggtgatg gtgaagttgc caaaaaagct
    21301 ggtattccaa ttgggaaatg gacagttgat ttccacgaag caggttcttt ttttgttctg
    21361 taattatagt gggagggtaa aatcattgat gaaatgtgtt cagataagag cgccagataa
    21421 aaatagaaga gacagttcac gtcgttatca cttttggtaa cggcgttttg ttttattata
    21481 taaaattctc aggaaaagga ggaattcttg tgtatgcaaa aacgaaaatg aattggttga
    21541 aagcactcgc attggtggct ttttctcaat tctgtttctt ggtgggaact gctcaagcac
    21601 atgcagaaga aacgacggct atacaaccta cgatggaagc cattgcccaa gtcgcttctg
    21661 aagtgacaga agtccaacca gcagaagccg gggtcccagc tggtgaagcc actgttgaac
    21721 aggcccctgt gacagaagcg ccaacggtca attccaaaac gactctcgat cagacgattg
    21781 gggaaacaca acacccaggg aatagtcctg gtacttcaca accagttgaa gaaactgcct
    21841 caattacaac ccctgcttca gaaacgtcca ctctagaagg agaaaaagct gccgaagcaa
    21901 cgccttctgt gcagccagag tcttctgaga aacaagcgga agaaaagaaa cgaatagaag
    21961 aaacagtgga acaaccagcg gctactgctg acaaagaagg aaaaaatgag gaaaacgttg
    22021 aaaaaacaat ctcttcaacc gcagctagtc aaaatcaacc aacgaaacca aacaaagaat
    22081 ctacggctag tattgaaaat caaaagaaaa aagagcagaa cattccaaaa acaggtacac
    22141 ctacactgtt agtaacagta ccaaccaatc gttcggttcg tgttcgccgt gcaaccaatg
    22201 cagctgtttt aggtggtcgg aaaattgatt ggggcgaaaa tattggtgtt acttctagtc
    22261 cgaacaatct aaacttcact ttaaattata tggttcgttt tgagattaat ggacaagtgg
    22321 cgttttgtat tgagcctggt gtctcagccg cagaaggtca agtttataca gctactgctt
    22381 tgaaaaacta tttgaaaaat tcaaatgtac ggaaaaaaac aagcttgatc tcttatttag
    22441 gatatgtcac aaataaagac aaatccgatg aacaatacat tgcggcacaa tttatgattt
    22501 gggaagcttt gggcacaaaa atcccaatca aaaatatccg tgttgattat gatcgtcgaa
    22561 aagcagaaat tcaacgtttg attaataact ttggtgaaaa agcaactttt aataatcaaa
    22621 cacatacggt aaaaattggc gaaacgttga aagtaaagaa taaaaatgat tttttgaaat
    22681 atgtgaaaga cattcaaaaa ccaaaaggtg tcaatgtatc tattcacggc aatgaagtat
    22741 ggattacagt cacaaaagag gcaccggata aagcaaaaat tcaattgaat aaaattaaag
    22801 ttcaaggtgc gccattagcc tatcgtcgtc caggagctca aacaattggt gtgttacatc
    22861 caacagaacc taatgcgtct gttattaatt tacaaattct aaaacaagga aacattcgtg
    22921 tgtttaaaga agatgcggaa actggtgtga aagcacaagg tgcagcttct ttagaaaatg
    22981 cggtctatgg tttgtatcaa gcagatggga aaaagattaa agaaattacc ttgaaaaaaa
    23041 ttaacggcaa agtacaggca gaaattaaag atcttgatcc tggcaaatat gttttaaaag
    23101 aaatcaaagc gccaaaaggt tatgtgcttt ctgatgaagc aattgaaatt gttgttgaac
    23161 ctggaaaaac tgtcaatgcg accgcaaaag atcaagtgat caaaggaacc attgatttag
    23221 tgaaagttgc taataaagat ttagtcgatt caacgaatcc agataacaaa ccaaaattag
    23281 ctggcattga aatcactttg acgtcaaaaa caactggcaa agtggtgaaa accgttgtga
    23341 cagacaatga tggttatgct acttttggta aaaataccgt tgtctttgat acgtacattc
    23401 tttctgaaac caaaggaaaa gaagggtata aactatttga accacttgaa gtcacaattt
    23461 ctgaaaatgg gcaaactttc cattatgttt tagaagataa agtaattgaa caacgtctta
    23521 aagtggtgaa agtggatcaa gaaacaggaa aagtgattcc acttgctaat acagaattca
    23581 agatttttga tactttagcc aatcgttatg tcacaatgga gattccaaat gatacagaaa
    23641 caacggatat ctttaaaacc aatgaaaaag gctttttcct aactaacggt acacttactt
    23701 atggaaaaga tcgctatcgt ttggaagaaa tcaaagcccc cgtaaattac gttttgaatc
    23761 aaaacccatt agtgttctcg attaccaatg atacagaacc gatcaaagtg atccattttg
    23821 cgaaccgtca agcacggaaa agtgtaaaat tattcaagta tgaagaatgg aacaagaaga
    23881 aaacgccgct cgcaggtgtg aactttacct tgtataacgg taaaaatcaa gcaattggtg
    23941 aatataccac tgatcaaaac ggggaaattt tagtgaaagg tctagttgcc gatgactatt
    24001 acttcttgga aaatgcccca ttagaaagtt tccaaccaaa tacagataaa caagcattca
    24061 cggttgcatt caaacaaaat gcgccagatg atggggaaac gttagtggtt tctgtacgta
    24121 attacttgat tccaccaaaa ctagaaacac aagcgtcaaa taaagccgat ggtgaaaaag
    24181 tggttgatcc attagaaacg atcgtcatta aagacagtgt ttcttatacc aacttgtttg
    24241 tcggaaaaga atacaccatt tcaggagtat tgatgaacaa ggcaacgaat gcgccaattt
    24301 tacaagatgg caaagaaatc acaagtacct tggcctttat tgcagacaaa gtcaatggca
    24361 caaaagacct tgaatttgtg gttaatgcta gtgttctgaa aggtcaaacg atcgttgttt
    24421 ttgaaaaact tttccgtgat ggcattgaag ttgcagcaca tgcggatatc aacgatgaag
    24481 cccaaagtgt gaaagtgaat aatccaaccg ttcataccac ggctgtcttt gaagacggat
    24541 tgacagtcgc agacccaaca ggattgttta ccttaaacga taccgttgaa attaccgaga
    24601 ttcttccagg aaaagcatac ttggtcaaag ggatcttaat ggataaagca accggtgaac
    24661 ccttgcttgt gcatggaaat acggtagaaa cgagtgttgg ctttattgcc aaagcagaaa
    24721 atgaaacggt gatcgtacca tttacctttg atttgacagg tataaatggt cgtgaaatcg
    24781 tcgtgtttga aagtcttttt agaaatgatg aagaactagc aaaccataaa gacatcaacg
    24841 acaaagggca aacggtacga gtaactaacc caagtgtacg tacaacggct acacataaac
    24901 ccactggctt gaaagaggtt aatccattaa cgaaagtcac cattacagac gctgtgaaat
    24961 accacgattt ggtcgttgga aaaacataca cagtcaacgg tgttctaatg gacaaagtaa
    25021 cggaaaaacc agtgctagta gatggaaaag aagtcacaag taccttaacg tttgtggcag
    25081 aaacaacgga tggtacagtc aatctagact ttattctaga cgcacgtgcg ttgcgaggca
    25141 aagaagtcgt ggtctttgaa gatctgttta gagaaggcgt attattggct tctcacgcag
    25201 atattaccga caatgaccaa accatcaaaa tcagtaatcc aaccattacg acgaaagcga
    25261 cgaataaaaa tggcggaaaa gagatcttgg ccttgccaaa tcaaactgtg cttgaatggg
    25321 tcaaagtaga cggtcttgcg attggtcaaa tctatcgctt aattgttcaa ggctacttaa
    25381 caccagacgg cacaccattt gaaggcactc atgcggaaaa agtctttgcg gccgataaag
    25441 aaatgatgga attcttattt gaattcttag tggacggtcg caatcttgca ggaaaaggct
    25501 tgagttttgc ggaatggctc caagcgaaaa cggaagatga gaaagaaacg tttgaagaag
    25561 tggcgaaaca caatgtagat ctaacaaaca aagatcaaac ggttcaaatt gtggaagcgc
    25621 caaaaccacc gcaaccagtg aaaccagaac aacgggttaa accagctact gttgtaccaa
    25681 tgttgccaaa aacaggtgaa caaacaagta gtatacttat ggttcttgga ttagtagtat
    25741 tagtcattgc tttaggtata acactttata aagtacgtaa agccaaagat tagtcatgag
    25801 gaacaagcgg ttaggatttt taaccgcttg tttgattgta atgtagaaat atttagaatt
    25861 tattttggtt tttaagagga ggaaaaactt tatggcagaa aaagcattgc gtatgaagaa
    25921 agagttttta ggtcaagtat ttttattggg ttcacgggaa cctaatccac caaaggaaat
    25981 taatggtgtg tctgggcgat atgttcaatt acaagcagag tgttcgcgag aagaacagcc
    26041 tgcttttttt gtttatctca cagctgaaga ggataaaaga ttacgattac cagaaaaaga
    26101 ggtgcgtatt tcatttgaag aagcttattt tgtttttcgt aaagaacgag tgaatagtcg
    26161 tgaaacaaat gatatgggac aaacagagcg tcgaacaact ggctatcaag atgttggtgt
    26221 ctttttaact ggtgtaaaaa ttggggaggt tttgtaagat gggattaaaa tttccaaata
    26281 attatgacat tacagaagca ttagatgaaa cttgtttagg agccgtacgc tttggcgcat
    26341 tagaagagtc tgatcgtgta tttgataatg aaacaggcga ttatacggga gaaattcgat
    26401 cacagcgagc acaattagtt tttggaaatc cagatgaacc aaagattgca cgacgagtta
    26461 aatttccagc agatgtagat ttgactggtt ttaaacgacg tgatcctgtg aaattaattg
    26521 atccagaata tcatgtggta tatattccag cacaagatgg caatcgtgaa tattcagatt
    26581 tagtgattta tgcgaaagga ttagagaaag tagaagctcc aacaaataat cctaatatga
    26641 aacaatcaca agaaaaaggt ttagatcaaa aacaaccaag tgttgattct aaggaaaaag
    26701 agaaaaaata aggttttttt gaaagaatag gaaggagtct tcctattctt tttatctaag
    26761 atagaaggaa ggggagattt tgaattcaga taaaaccaat caaatacttt gagagattgt
    26821 gcttgttatc aaaatatcca acaattgatt gagtattttg gagacaatcc aacgattttt
    26881 gtacaaacaa atgcatatat ttgtgcggtt attgggcagt gtatgttttt acgtgatctt
    26941 gttcgttttt cattaccgta ccagtggaaa caagatcatc aggaagtgat ttggattcgt
    27001 atagtacgaa tatgtaatat gtgtgcacac ccttataaaa atcgattaaa tctttttcga
    27061 ttatgttttt ttactaaatg tgatattcct gtattagttg ctttttgtca aaagttttta
    27121 gcacaggaaa agtaaaaaca gaaaggagga atgtgacaat tgaaagctca ttttttcaag
    27181 tatcgtggtc ggcgaattcg ctatttcaat cgttatttat ggttttgcta ttatggtttc
    27241 tttttgtttc catttttgat tctgttaggt tggtttagtt ggaaagtatt ttatccacgt
    27301 ttaagtacgt tttcgaattg gcaaatgtat cttattcctg gaataagtat tgtgttgtat
    27361 ttgttgctgg ttagtgggtt aattttaggg ttgatgcatt ggtcgcgact aaaagaagga
    27421 tattttgcct ctgtttattg gcgtcagtta cttgttcgaa tgttaattga caatcggttt
    27481 gtttatacaa agaaacaagt tagtgagaaa caaacaaggg aaaaaatgag attaccaaaa
    27541 gtttattttt atcaaaagaa acaagaatta gtggtttctt ttcctttaga tggtgggcgt
    27601 tttcacgaac gatttttaaa aatgggtcat ttgttatctg aagtattttt gcgtgattta
    27661 attcgtgaag aacgagaaaa agcccgaatc aattatgtat tcctttcaga ttctggtcgg
    27721 attcctattg atcaatgtat agcagaaaat ggacgtattc atttaatgaa aactttggat
    27781 tgggtatatg atcaatcacc aaatatgttg attgctggtg caatcggtgg tgggaaaacc
    27841 tatttattgt attctttaat tcaagcttgt ttaagtgttg ggacagtaga tatttgcgat
    27901 ggaaaagcgg cagatttagc agcattaggt gacgtcgatg tattcaaagg acatgtgttt
    27961 tacaaaataa atgaagaaat gattatttgt ttacgaaatg cattaaaaga aatgaatcaa
    28021 cggtatgcct atatgaaaac catgaaagat cctaaatatg aaccagggaa aaattatgct
    28081 tattatgggt taccaccgca ttttatcttt tttgatgaat gggcagcttt ttatggttcg
    28141 ttggatatgg aagcgagaaa tagagtcgat aaattgattc agccattagt attaaagggt
    28201 cgtcaagcag ggatgtacat tattttagca atgcaacgac cagatgcaga atattttcca
    28261 agtggtgttc gggataattt aacattccgt atttctgttg gtcgattgtc tcccattggt
    28321 tatttaatga cttttggaga agattttaaa aataagccat tttacaacaa agatcaacct
    28381 ggtcgtggat atgcttttcc aggatttgat gtacctgtag agttttttgc gccatttgtt
    28441 tacaaagatt atcactttat caaagaattt gagaaattta ctgaaatgat tgtctatgat
    28501 tttacagtaa aagaggatag tcaagatcaa acgatgggag atgataatca gttgttacaa
    28561 gaacaactag agcgccaaat gtatttagca aaagatccaa aaggaacaag tttttctgat
    28621 gcgcatattt tgtaatcaac taaggaggtg aagttaaatg gcagagagtt gttattatag
    28681 agtagctaca gcaatacgaa tgattaatcc ttctctttct tccagaacgt tttatgattg
    28741 gttgaatcgt attgaacaag taactgatta ccgctttttg cgcaaagaac gtgtttttac
    28801 aggaaaagtt attaatcaag tattgctaac gaaaaaagat atagaacgat tgactcgatt
    28861 gtatcattat cgagtagatt tagaagagga tttaactttg tcaatttatc gcgttttttc
    28921 tcctgaaaaa tatagtgaaa taacaaaatt agatcattta attttgtagt tattatctat
    28981 cgggagggct ctagacgtag tctggtagcc gcactctgcc tggcggtgcg cattaaggct
    29041 gcgaagcatg ggcctataat gcgcactcgc tagcagcgtg tgcagctcac aaagaggtcg
    29101 tgcgcttgcg cacggcctct ttgtgtaaag ccccccgata tataatatgg ggggcagaaa
    29161 taacataaca catagaaaaa agttttataa acccttttgt atcaagtgat tatctaaggt
    29221 cagcagttgt actacttttc ccaaaaaacg agggggacta gttgatatat cggtgtttct
    29281 aaagggttaa aaaaaatcga ttttgttatt ttataaaagg agcgagaaaa tgacaccgat
    29341 tgagctaaaa agctacagaa agaagttaag tgcaattcat aatataagtg gagataaaaa
    29401 gccgctatca caagcaagat ttgcgcaatt gatgggctgc tcaaaagatt acattagaaa
    29461 gatggaacaa gggaaaagaa aaatcccaga ggattttgaa caacgaatca aggaacgctt
    29521 tcgattgtat atgaaaagcg gaatagatct tcgagcaatg attgattatt tgcgtctttc
    29581 cttttttggg acagactaca aaacagtgat tcaacgtgta ttacgaatgg atctgacaga
    29641 atttgaaaca cgtccaacgg gcttgtatct ttttgactgt ctttctgttc gtgggaatat
    29701 ctgggtgttc tggcattcaa aacgaactgt aacagaaaat gtacttgtgc aattttcagg
    29761 acaaggttgc cgggaatatg aggaagtcat gcgtgaacaa caaacagatt ggcgaacatg
    29821 gctatattcc atttggaaaa atcaaggaaa gttggaagct ggttatacac gtgtgcaatg
    29881 tagccgattc gatattgcgt tagatgaact ttggggattg gaaacggaag aacatttcga
    29941 tctctttgaa ttactagaaa aacaaaaagc aggtttatta gaaatggact ttaagagatt
    30001 ccagaatatt ggcggttgtt ttttagatga tggctatttt cgaagtgaag gattatcttt
    30061 gtattttgga tcgcgaaaga gtcctctctt ttttaatttt tatgagaaac gttttgaaat
    30121 tgcgaaccga gaaaaaattt cagaattaga agcattaacg aaatatggta tttataatcg
    30181 atatgagtta cggttagcca atgagaaagc aacacaagca gtagaagcat ttattttagg
    30241 tgattcaccg aaacgtttag gagagattgg cgttggttta attaatgcaa aacttattgt
    30301 ttgggataga ctggaaagtg atgcacggat tgttgataaa cgatgggcaa aattatttcg
    30361 ttcgatggaa gaattggatt ttacagtaaa gccagaaaaa ttctcattag atcgttcaga
    30421 acgctggttt ttgaaacaag tagctccgac attaaagttg ttacaagaag cagatcgtat
    30481 tttaggaaga gactttgtac aagaagggat tgataatgcc gaactaaatg acgagcaaca
    30541 aaactatcta gaatggatgg gaacgtcagg agggaaaatt gcatgaatgc atatacgaca
    30601 acagaatggc tgcgcctgtt ggatttaaag gctgcaatcg aagcattaaa tgaaaagatg
    30661 gttgatttgt cttattttcg ttttcgagtt ccttatattg aacaagcggt aaaagctgga
    30721 cgttatcagg aaaaagagaa ctggcaagaa attgcacgct tattagaagt tcgtaaggga
    30781 tacgaacaag aactcgaaga gttggaattt agccgaagga aaggaaggct agaattcatt
    30841 cgcttttatc gattttcatt gccaatacct gcgattttag cggttaaaaa aggctgcgat
    30901 aaaatgaaga tatatgaaaa ctgtgtggca gcacttagca gcgaaaaacc tcttatggaa
    30961 gaaatttcat tggtgactgt cacttgggaa atgagtcgcc agccaacaga agaacagaca
    31021 tatctttctt tagaagagat tgagatagaa ttagaggaaa ttggtcgcta tgccacttgt
    31081 tctacctatt gtggatcggt cattagtatt gctggtgtga ttgtctaaat gaaaaaaatt
    31141 atgatttatg ttggtgcgta ttggtcacgt gatccaacag tattagaaaa tccagaggcg
    31201 gtacactatt gcttgcgcca attattctat ctgtataaag aacgattaga atcgttgatt
    31261 cgtcagttac catatactga cagacgttta gatgaacttc ttctaaggta tccagcaatg
    31321 tataaacgac gaaaaaatag attgttacca gaagagtatc ccattgaaaa acatgaactt
    31381 gaagggcgat ttgtggctta tttctatgat gatgttcgta tgcgcttagt agaacaacga
    31441 atggaaatag aaaatgatcg ctactatttt atcaattatt gtaagaagcg taagtatcaa
    31501 gtaactgatg atttttatga ttgtatttta caagatgggg aagtgattct atccaaaatt
    31561 gctccaagtt ttcgtgaact tgtgccgatt gattttttga aaaaatgtca tttgcggatt
    31621 cttccgtaaa aaagagctat aaaaggaaag aaaagtagaa gccaaatcgg tttctgcttt
    31681 tttatttttt ttaggaagga gaagatggta tgtcactgga atttttagga gagccaattg
    31741 aaaaggaaga gttcgtttcg cattatatgg atttgtttat tcaggtgata aaaaactttg
    31801 tgcgattgat gaattttatc cacgcgaaca agactatcta gccgctgaac gaataaaaat
    31861 cagtttatta tgggaaaaat tcacagatga aaataaccga ccgccagatt atcgctattt
    31921 atcagattgt ttaacgaata atgtgctttc taaagaatac ctatttcaca aacgtgagaa
    31981 aaatcaaatg tcggttgaac atttttgtga ttgttatatt gcattattgc gtagtcaaca
    32041 gttattaaca gtagaacgat atggtgcaga gtttggttat gtcatgcaag ctgagcgtca
    32101 tagagctaca agatgctatg aaaaagaaga tcaagtgatt gatggctatg aagaattatg
    32161 tattcgaaac aatcgctatt tgcaacaacg tttatatgaa caattgatga tggatttttc
    32221 aaatctctat agagggtatg aatgttcgat gattcaagaa aggtagaaga aaagggggaa
    32281 tttttatgtg gcgattatta tttttggtgg tatgtggtat ggcattgttc tatgtgtatc
    32341 gtgtctatct ctatccacga atggaacgat ggacaagttg gtatagagat cctttaaaac
    32401 aacgaaaagg attgaagcgg tatcgttatg aattacttgt tgaattttcg gatgggcgac
    32461 aagcacagta ttattttttt gcaaactatc caaaatacaa caccagtgaa ctattgattc
    32521 aattattcaa aaataatcca tatgttgggt tagaagaaaa cggacgggag ttcttttatc
    32581 gttcagataa tattagtgcg gcgtctatga acaaaacacg aattgcataa aaaattggag
    32641 gaataatcat gaaaaaaaca acattagcag tcgtaacaac actaggaatt tcattatttt
    32701 cgtttcaatt agggagttca ttggtttatg cagatgaaac tgtagaaaca cctaagtcag
    32761 aaattgtaga aacattgcca ggggaaggat taccagatgt tgagacagag ctaaatggag
    32821 gaacaacgga aaaaccagca gaacctgaac aattgcagtc agagaaacct gaaaaagagc
    32881 cagtgacacc agaaccagag tttcctgaat caactttacc gactgattcg atcgaagaag
    32941 aaggtgtgca tagttcaaca acaacggatt caagtatagt cacaactccg gaacaatcag
    33001 gaacaaccag ttcttctgaa aagaatactg attcgtcaag tacggaacag ccaacgatgt
    33061 cgtctaccag tgaagaacaa aaagaagaac cgaaacaacc tgttgaaaaa tcagaagcaa
    33121 ttccaaaaga aaataaacct attgttccag caaaagaagt cacagtatcg gtaaccccaa
    33181 gcggtgaaat tacgacgaat acttctcaag gaatgagtgt accgattgtc actagtaatg
    33241 tagaggaatt gacccatatt ccaacaccaa ccaccccatt aaaagtagca ggtgatcaaa
    33301 caattgttgg tgtaaaagat ggtattccat taatccaaga tagtgaaggg aatttggtaa
    33361 aggatttgtc gattcctgta aagaaacttc caagtggcaa tattgaaatc aaaacagcag
    33421 atggaaaaac aaaagtctta ccaaagactg gtgaagaaat acatgttgca ctttctgttc
    33481 taggaggagt gttgacaagt attgctggat ttgttggata taaaagaaag agaaaaggaa
    33541 tagaaaatga gggtaattga atggactatt tttcagaaaa acaagcttat cgttgtcaat
    33601 cgtacgtact agtaaaaaca tactagaagg agtagcttat gaaaaaacga caactacggc
    33661 ggaaagaaaa agtttataca gagaaagtac cgaagcaaaa gaaaatccat tcaaaaaaag
    33721 cagtgaaatg gatttggtgt ttggttttat ttctttgttt ttcagggggc ttggcatttt
    33781 ttcaatccat gaaaacgaag gttcaagtgt cgtttttgaa agatgaaatc caacaattac
    33841 aaaagaaaga agtacaaagt cggtcagaat taacgtacac acctgaaatt gaatccttta
    33901 tgaatcgttt tgttgctttg tatatgaata cattcgataa tcatgaacaa gaacaacaac
    33961 gtcaagaaac attaaaaaaa gagttttatg cacaaaactt tattcaagaa ccaggaagtg
    34021 tttcaggtgt tcgaaaatta actgctgctt cgtttattgg attaaaagaa attgaaacca
    34081 ttccaactgc tagttataaa gtaacttatg atattcgctc gatgaatcca gagagtaaga
    34141 aagaaacaag tgtgacaatc acacaagtac tcaatcttcc cttttctatt tcaaacaagg
    34201 gctgtcgtat tattgcttat ccttatttta cggcactacc aaagaataca gaaaaacaac
    34261 gaatgattac ttatgatgac acattatacg aaacggttga tgcgtcggaa gcgaaagatg
    34321 ttgaaggatt tgtggaagat ttcttagata agtatgcgaa aaacaatgca aaagatatgt
    34381 catacatgat gaaagaacct gaaggactca atcaaacagc taaagttgat caagtagaga
    34441 tgaaagtatt gcgttataaa gaaacgaaaa aaccttttat tgtaaaagca acggtcgtct
    34501 ttcgagatgg tgatacgtca cttttacaaa aagaacaaat gacgattgtc attacgaaaa
    34561 aaacaaatca gtattatgtt gaaaaattaa cacataattg gttggatagg aaaggagaag
    34621 aacggaaatg acactgaagg gaattgtaga ttttatatta acgcaaggtg gctatttttt
    34681 aataatggtg gttgtttatc tgggattgcg aaattttatg aaatcaaaag taggaaatgc
    34741 attaatatct atcgcagcag gtgccgcagt ttatttcttc ttaaatgatc caacacgtgt
    34801 atttgatgcg tttggtaaaa tcattgaaaa attatttatg gattaggagg atagtgaagt
    34861 ggattgggaa ccttatgatt attcgattgt ttatgcggaa ccttatcgcg tacaacagat
    34921 tacaagcaat tggcgtcttc catttccagt tgcattagtc aatgcagcaa cttttttgtt
    34981 ggtcgtaatc tttgaatatt tatttttacg ttcatttatt ggttgggtca tttctttttt
    35041 tccaccagca ggagttgttt tttatatagg actcccctat ttatgtgtgt tagcactggc
    35101 aaaactaaaa cctgatggaa aaaaagtgca tttttattta tgggattggt tttgttatat
    35161 gattcgtatg atgaatggtg attgtgtgta ttataactgg gacaaggtat caaacaatgc
    35221 attggaagaa ttactttttg tgaataagta tgtttattta gaggattaga aaaagggaca
    35281 atcaactggt tgttcctttt ttattgggag gtgaaattca ttggtgcttg taaaagaacc
    35341 agtaaaagca ttcaagaaaa attgtttgtt aaatggagag gattgtatct gggcctacta
    35401 tcatgttttt ccacgaacaa tttcaaaaaa cacaccaaaa aagacacagg aaataaaaga
    35461 aatgatggct cgtttactgt tgcttttagc agattatgaa gatgtggagt tggtgatgta
    35521 tccacgaaca atgaatttac ggacgaagtt tgacacatta ggaaagggat tttctcccga
    35581 tagtcaagca attggtgcgt attatgcaaa agaaacagtg acattgttgg aacgagaagg
    35641 tcaagtctat cgtccttcat ttattttagg aatcaaagtc aaagaaaaag caacggtgga
    35701 gagttttcat gatgtaataa atctaatctg gttagattta gcaggaagtt tagcacgctt
    35761 atttggatta gaagtagatg atttggaaac tttgttttct gaaagtgatc cttatgtaaa
    35821 agaagtgaca caattacttt atagcttttc tattcgtccc ttagtaaaaa aagagctgtt
    35881 gtatctcaat cgtctgcaat atattcgagg aatggctcac aaagtagaag aacaaaataa
    35941 ttgggaagta ctgaaagaca atcaaggaac gtatgtacgt ataccgaagg aacataaagg
    36001 ccttcttcaa ttagaagatg agttagggag tagttattta gcattgttgc ctattgggga
    36061 aacacctgaa aatatgagaa attgtgatct atttcaattt gctcaggatc tttctttccc
    36121 agcagaattg cgaatgaaaa ttcactatcc acgcttgaaa ggacagggag gtattggttt
    36181 aaaactgaat tggctatcgg aacggttcaa aacagagcat aaggaattgg ttcaaaatga
    36241 tgaagaacct agtgaacgct tattaactgt tcgaggatta gtaaaacatt taaagcaacg
    36301 agtagataat gggcaacctg tcgtcgattg gatcgcatgt tttattgtat acggtcaaac
    36361 ggttgaagaa gttcgtcaaa atagtgcaac ggttattcaa caacttcata cgattatcca
    36421 tatccaccgt gcaaaaaatg atcaacgaga attgttctat aaatgtttat tagggcaacc
    36481 attgggacgg cagttacatt ggaagcaccg aacaactgta gaagcagttg gcgaatggtt
    36541 gttttcagca gtatcagaat taggtatgga atccggctgg tatattggtc ggcaagatac
    36601 attaggggat ggtggttctc gaggagaaaa aacaccatta gaagaattaa tttatgcgtc
    36661 aaatcgtttt gtctttttga atcttctagc cattgcggaa ggaatcaaag gtgcgttgtt
    36721 tgatgcgcct catgtagcag taactggaaa aaccggtaaa gggaagacct ttttagttgg
    36781 cttgctcttt ttgtatagtt cgtttatgaa tgtacaaagt ttatttgtgg atcccaaagg
    36841 agaaaagcgc aaatggttta cgaaactcat tcaagacccg tattatcaga aacattaccc
    36901 tttgtttgta gaacatttgc aaaaaatgag ttatgtcacg ttagatgcta caaatccccg
    36961 taattatggt gtattagatc caattgtttg tttatcccga gtagatgcga aacaagtagc
    37021 ccaggatatg attgatgagt taagtccgtt aggtaccaat caccttttaa aaggggcggt
    37081 attaaaggga atccaagaag ttttagttca aaaagaagcc ggacaacaag ttggcttgat
    37141 gcatgtggtc gactatttag aacaaatgga acaaaaagag gttcgagaat atggtgagtt
    37201 tttacgcttg acggtagaag attcgatttt acgtttagga ttttcttatg gagaaaaccc
    37261 gggattagac tttaatgcca aaacaacgat tttagagatc caagatttga aattaccaaa
    37321 tgacaatgtc cgaccagaac tatatacaga tgcggatcga aagtctttgt gtttgatgat
    37381 tagtttaggt cgtttttgtg aaatgtttgg aaaacgagat agtagtaaga aaacagcgat
    37441 ttattttaca gaagcatggg tatttaataa ttcgaacgca ggacgtagta ttattgcagc
    37501 aatggcacgt gtggggcgtt cccagatgaa tcaattagtg ttagatacac aatttattgg
    37561 tgacttaggt tcagataaag aaaaagggaa ttttggtgtc gtctttgctt ttgatgaaga
    37621 cagtgagcga gaaaagattt tgaatcattt acgtttggaa gtaaatgaag cgaacttagc
    37681 tgaaatgagc cacatgatta aaggacagtg ttggatgtta gatccctatg gacgtgtagg
    37741 aaaactcaat gtacacagtt tgtttgaaga aatgaccgct gcattacaaa caacggaaaa
    37801 aacaagtcac tctcaagtag aagaacagga tacgttaatc atgcaataga aatgaggtga
    37861 aacaatggct tatataaagc ataaggaaaa gaaatggtgc gttttgtttt ttttaacgat
    37921 tggattcgga ctgctttttg ttggtggatt ggtgtatgcg gcagaaaagc aggtggatca
    37981 atcgatctat gagattggga aatttcatat tgataccttt tcttcttatt tatctgatag
    38041 tgaattttca ttaggcaaaa tgttatttgg ggcaaatggc acagattttc taaaaatgat
    38101 gacgaatatg ttctttagtt taagtaaatt gatttggcaa ggccttgatt ttgtcattga
    38161 gaagctctat gaaggagctg caatgaacga gttaattcac cagtttttca ctttttcgga
    38221 tactatttat tcaaaaatat acgatcctat tggtgcgggg attgtcgtct tgtatgtgtt
    38281 atatctattt actcttcgta tatttagagg gaaacattac gcaaaaatgg tgtttattcg
    38341 atttctcttc gttgtcattt tttcaatggt ttggtttggc tatggtagta acgtacctag
    38401 taaaggagaa gcttttacca aagggttaaa tgatttgtcc gtggaggtag aaggctttat
    38461 tttttctgct acaaatagtc tagatgaatt ggcgacaaaa gatgtcaatg gtgttttagt
    38521 gccaacgaca caaaaggaag ccattcaaaa agtgcgccaa ctttattata aagcggctgt
    38581 tgttgatccg tatatattgt taaattatgg gacaacaaat ttagaagaat tgtatcaagc
    38641 agagattgaa ccacaagaat ttctagccaa ggaagcgtca agtgaagaat tatctgatat
    38701 tgagacaaaa gtgaccactg ctgcaggaga agatagaggg aaaaagaagg cttatcgtgt
    38761 ctatattcaa ccaactaaag ctgtttataa agcagtcgtt ggttctatgg tgccattgct
    38821 taatctaagt attggattac cacttgtagt gattggcatg attcgtttta tctttcaaat
    38881 gttggtgttg tgtttattac ttgtgattcc tttttcatta ctcgcttctt ttgttccagt
    38941 atttgattat atgctcatga ataccttaaa gtcctttttg ggcttgatgt ttcaaaaatc
    39001 tttttacagt gtgattattt tggtggcatt tttgatctat aacatagtag acgatttaat
    39061 tccaatgaat actgtttttg gttttttagg aaatatgttt gtcaaagcac tcctatcaat
    39121 tttactcatt gtaaaacgga aagatttatt aaagaaacta gggttaggag ctgcagatca
    39181 aactataaac aacacgaaaa acatagcaag tcattctttg tctcaaatga aacaactgcc
    39241 tggtcaacta tcaactgctg gacaaaattt ggcaatcaaa ggtgcaggat tagcagggaa
    39301 tgtgtatcga gcaacgaatc cactcgcttc tgcagcgata catggatttc aaaagtttca
    39361 acaaaaacgt acaccacaag aatcggtaaa agggaggcaa gtggttaatc cctttgaact
    39421 aggtgggcgt tcaaatcaag ccttgcctta tagtggtcgt catgttcgtt atcatggggt
    39481 agagcctgaa atgtcttcta ccaaatcgaa aacagagtgg aattctggtc tttcaaatgg
    39541 tttgattcca aattcgtcca tgaattcagt aagaccaaaa caacaggtac aatcattggc
    39601 acaattgagt aagcaacaag ggaataatca aagaaaacca ttgttaaata aaggtatcgc
    39661 ttttgttggt caatcgattc cgttgccttc tggaaaagta cccgtgccac aattaacagc
    39721 tgctggttct ctttcacaac agattcgcca agtgaaaaat caggcgaaaa atgggagtta
    39781 tccagcaatg cagcagttat tgaaccaata ctctgttcct aattcgtcgg tagccactct
    39841 atcaggaaat cgttctgtgc aacaaccggg gcaacgttcg tctgaaagta aaccgtcgat
    39901 ttccgcacca aaatcgttac aacctgcatt ttcttcttta gataagccaa cagagcaatc
    39961 ggaaaaaata gaaaaggatc ctaaaacact gccgattttg gacgcaaaac caggaactga
    40021 ttttacttta ccaaaaggac gaacagtcca aaaaccatta tcgaagaaag gatgaggaag
    40081 aaatgaagaa agggtgtcta ggttgtcttc ttttctttat tcttcccttt tttctattgc
    40141 cattcttttt ttcaggagaa ctttctgagc atggaggaga agctacaggt ctagctgtcg
    40201 cttttaatgg ggaatatacc gaaggattac cgattttttc agagattaaa ggacgtggtc
    40261 caatcacaga tgaacatgcg caagcagcag ttggtgcagc tgtaaagtat cagttattac
    40321 cgagtgtgat tctttctcaa ttaggctatg aatcagctta tggacagtca caatctggaa
    40381 gaaacgatac gaactttttt gggattacct ggtttcctgg ttgtccctac ccacaaggtt
    40441 ctgcacgtgg aattggtggt tctgaaggtg gtttctatat gaagtttccg aacttaaaag
    40501 cttgttatga ctattatggc tttatggtgg cgagccaaag caactttaat caatgtgtgg
    40561 gcaataaaga tcctggaagt tgtttattga ttctaggtcg tggaggctat gcggcagcag
    40621 gtattaccga agggagtccg tattatcgag gagcaatgag tatcataacg tcctataact
    40681 taacggaata tgatactttt gcgatcaagc attggaatag cctaccaaca aaaaaaactt
    40741 cgcttattgc aggaaaaagt aaaggcaatg cgaaggtttt ggatcggatc attggacgat
    40801 ccgtaaataa tggggaatgt tatggtggta cggcatggta tgtatctcaa ttaggtggcc
    40861 cacagttaat gggttctgga cacatgtttg cgatgttaat aggggaagat tataactgga
    40921 caacctatgg ttggcaagta atcatgaacc caaaaccaag tgatttacaa gcaggagatg
    40981 tggtgaattg gcaagcaggt ggtgcattgt ctcctggaat ctatggtcac accggaatta
    41041 taacagatgt ttcatatggc ggacaacatt tctctagtgt ggaacagaat gccgagcaag
    41101 gacggattat ggctcggtat caacgcacgt acaatcaaac aaaaattcgt agtctggttc
    41161 gtaaggtgaa ataagaaagg cagtgactag aaacgtgaaa aaagggataa ttttagtatt
    41221 tagttggtta tgtttgatag gtcttactgg ttgtcattgg ttttcttctg aaaaacaaaa
    41281 aacacaattg agaacgacag aagaaacaat cgaagcagta aaagaaacaa gtggaactct
    41341 tcaaagtact gaaagtaaca gtcaaattgg ttcattagaa gacgagacag cgcaacaaat
    41401 gcaaatagat gaaatgacaa aaaatttctt aaaagatttt gctagaaaat ggagtaattt
    41461 cacagatgtt tataaacgca atcaagctgt gagggactat atgacagatc gttgtattaa
    41521 agacaatagt attgatgtag acccgcatgt acaaatgaaa acaactggga aactttacca
    41581 ggtgacacaa gatatagaga atccggatca atatttgtta tttggagaag aaacaatgaa
    41641 taaggttact caatttgtat tacttcaatt gaaagtagat caagaagctc aaaagattga
    41701 tgcgatcaag atttattatg tacggagtgc gtattaaaat aaaaaatgaa cactcatatt
    41761 tattatacac cgaagaaata gaaaaaaaca gactgttttt ttaagaaaaa ctatgtcatt
    41821 ctttacttga aaaaagttgt tataggacag aaaggataaa acaaaaacgg aaaaaatatg
    41881 tcttatgaat aactataaga actattctat tttttaggag atggatacga gatgaaaaaa
    41941 ctaattggct atagtgtgat gtgtattgga tttgttggtg tgggattgtt tgtatcgact
    42001 gaatctgctt ctgcggctga atggtataat cctatctggt ataatccgaa cattgaatgt
    42061 caaaaaggct atccgtatgg accgacaaat ctgaaaaatg gaaaatgtag agtaaattgg
    42121 aatggcgttg tagatagtgt aattactggt tcaatggact ctgctctaca tggctttacg
    42181 ggtcactaga aggaggaaga aaatgtctga agagaaaaaa gaaatcgttg aatcattagt
    42241 agctttaaaa gattctcttt ctaagattga atatgttgat aggcaagaaa ttcaaaaact
    42301 aattgatgat actattattg aaatccaaga tgcgcgttgt gaaggtataa aaatttctgt
    42361 agctttatct aaagtaatag aaaaaatgaa ccgttcatta gcgtttaatg gattgaagct
    42421 agatagacaa actagtctga tatgggatca tttaaaagac ttgtatgaca agtctaaaag
    42481 aagtgaacgg actgctgtat caatcttaaa aggcctttgg ggaatgaatt cataaacaag
    42541 atatttaaaa agtaacttat tttttatgga ggagaaatta tgaaaagaat aattaaaata
    42601 tttggtgttt taggtgtttt cttattaggt ttaagtactt ttgttagtac tggaacaagt
    42661 gtgtatgcca cagaaaaagt gaatacagtt gatttagaaa taaagaataa attagtagat
    42721 gaattaactt tttattttga tacagttggt tttttagacg aacatggtgt ataccatata
    42781 aaggattttg gtgctattcg tgaacgaatc agtcaagata acgaacaagg aagagcagca
    42841 agagtctttt atgaacatat tattgttcct agaatggaga aagttgattg gaaacgatat
    42901 gctggatgtg tagccattaa ttctcttcct ggaggaggag tggcttgggc tataggtacg
    42961 cagggagatt ttattgaagc attaaaagct tttaattttg aaaaagctgc ggatttatta
    43021 ttaaaaattg cagaaaaaca attaggaaaa gctgcagcta aagagttagc taaggtaaat
    43081 attgtagcag gaattgcagc agctgctgct agctgtgcat tagagtaaaa gtttatgaaa
    43141 agtttagaac aagagcatat ggcttttaaa caagcaatgt ttaaagaaaa tatctattta
    43201 aaccataact atattcgtgt ttctaaggca tgttcaccag tattgaatat gcttggaggt
    43261 ggaaatggat tatatcattt actgtttgtc gatgtttgtt ggttaatttt tttaccagat
    43321 gaactagtta tagtcaatga aaaaataaca agtaaaaatg aagtgtttaa ttattcttta
    43381 acaagaatta attac
//
LOCUS       DACGEU010000013        39256 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.013, whole genome shotgun sequence.
ACCESSION   DACGEU010000013 DACGEU010000000
VERSION     DACGEU010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 39256)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39256)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39256
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.013"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..2418)
                     /locus_tag="IXR40_000680"
     CDS             complement(<1..2418)
                     /locus_tag="IXR40_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015508912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360551.1"
                     /translation="MKIIEKKIANKKINWLVVNFLVLIAMIIFTSNIAHASIFNWFDD
                     TKSQTEFLNNSLYRPYLKKYNGDFLSQFGIWLGWAVVKGMFTVTDSIQNMIPDVLDLF
                     NFIESTGLNNVYQSAVNTIVIGLMILSLMFVGYKMITGKGTVDLKSVGMNVVMSIALI
                     LLMPTMISSGIQFAKTFYKDSTTITNSDDGVAWSLIKQGVTDLAYINKTDQYSSIDKT
                     EDRNNLTRKNFQQTDLTQVLTDKVIDKLEKENPIADNLRYELVENSNNEFVATKFSDN
                     FLSTFSDSLKSGYYRYQANLWGISIGLTALAIAYVFSAFVIITAILELAFKRVLGVLV
                     FATDIETGQRSKVVLSDILQCYLTVGFQGFGLSMFAMFINFLNSGQGISTNIFIKTIA
                     YICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGSNGFNRAKGSGE
                     GEDRKPEKNFGETLSKKAGKTGRALGYAHERGLSGLASDGATMASERATKPFKSMRDI
                     ANDTKNKFKEGLDDGTVSAINKNSKPMLAKNKEDETGKYADSVPTRLSDRKDGAKVEN
                     ADRIMSSSERMREAMKNNAESNNNPASAIQQKVQQDIEERKNAMHGQAKSAEELINQK
                     RHEAKYTPEAMNREEIMLRKRVEGRTGANIDGKEALTKERIQEAKNSNTGLEKLVKEN
                     PQNSTSSHGGRSVDVRENIQGSLNGHVGRNVDVRENLQSSSNAQGTKTIDVRENLQSS
                     STSQPKTVDVRENVQNSTSSQGFKSVDVRENVQGSSASQPKTVDVRENVQSSTSSQGF
                     KTVDVREN"
     gene            complement(2405..2623)
                     /locus_tag="IXR40_000681"
     CDS             complement(2405..2623)
                     /locus_tag="IXR40_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360552.1"
                     /translation="MIKNRLIDQVWCLDQNTDSLELIETICFNTIVLDLRAENDNCVT
                     HVIINQKMAQKLSESLRKWAKGGNDENN"
     gene            complement(2699..3751)
                     /locus_tag="IXR40_000682"
     CDS             complement(2699..3751)
                     /locus_tag="IXR40_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HAQ4360553.1"
                     /translation="MNEKEVESLVEKQGYSNSDIYAELYYQYPIFLNVNEKYKKMKLS
                     SKLVYMLLKDRNRLSLKNNLYDENQKIFLIFEIKNLVEISGMSKNTILSALDELQKVK
                     LLVKRKNGFNKSKMQMFPNFYYLLKPVLCKDDVYKINKITHQENRQKNLIVQNLNYGT
                     NQYSVDSSKFELCDTSMKTRDKNNFADSSKNELELYKSYKDSKDIKESHNDDLLESLS
                     TKNNKLDEELIETFIEENLLKQIWGESIVNCLKLASNSDYRQFDNWYKKFKYAIRSAE
                     KEQKIQLKIIYEICNNKYFVDHVREQLSMTLRDLIRRAKTDHRIKQKDDYIFASLKNK
                     ALELIELQISEGIDKQ"
     gene            complement(3904..4230)
                     /locus_tag="IXR40_000683"
     CDS             complement(3904..4230)
                     /locus_tag="IXR40_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360554.1"
                     /translation="MASWLIEEIENERRKIMDAGITVMLDKQQTNQLKNYVFEMTKEA
                     IDQARIDTGLERPFLKGKEMAKYLNVSYTTFLKFKRMGLPVILLEKMELFSKEECKKW
                     ILSHQI"
     gene            complement(4242..4442)
                     /locus_tag="IXR40_000684"
     CDS             complement(4242..4442)
                     /locus_tag="IXR40_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4360555.1"
                     /translation="MITLNDQFIRSLRRHRADLILTKNDAAKLIGINRKTYVKIENGS
                     KESIRASTYQKLVNWLLNDLKI"
     gene            4517..5167
                     /locus_tag="IXR40_000685"
     CDS             4517..5167
                     /locus_tag="IXR40_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4360556.1"
                     /translation="MSIKILLNLWFSCYNSLEFTIGGVTLNRIKFYIDSSKKTIKQIS
                     TETGINYTTLTNYYRGERNPRNTETWNILADYFHVPVSYLMGLDETNSIEQPNLDRIK
                     TARLEKKDKIVKNIASLDSDYFTELSNLYFSMTSLLEVKLQEDDSDFLFLKSILEDSF
                     EYTILFAKQKKFINKALNLNIDERKELESELFGNLTQVQVNNLKREITARLISKLQ"
     gene            5222..6388
                     /locus_tag="IXR40_000686"
     CDS             5222..6388
                     /locus_tag="IXR40_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAQ4360557.1"
                     /translation="MSIQKYTTKSGARYSVRLYVRKDENGKQEYYVKKGFKTEKEAKL
                     HEARKKVEIEDTGYHKPSNDLFITVYEEWLPSYRNRVQETTYQRTKDLFRLHILPKFG
                     NKSISKITPVHCQNAVNEWALKFKNIKQLKSYSSQIFEYAIFAELLHRNPMANTNLPK
                     REKKENENYFSLEELKAFWDILNKEEPLKHILIFQLLITTGIRKGELAALHWSDIYFE
                     EQLMYVRKSYATIRNEEKNARRKTVRIQKNTKNISSERILPIDAQTIEMLKIWKKEQA
                     RELLQFGINTNTKNQLIFTYVNADGDINQPLHADYSNNILKRLEKKYKFKHVTIHGFR
                     HTHATLLLEGGASIKETQDRLGHKNAETTLNTYSHVTEKAQRNALEKFIAYTGL"
     gene            complement(6477..6869)
                     /gene="rpsI"
                     /locus_tag="IXR40_000687"
     CDS             complement(6477..6869)
                     /gene="rpsI"
                     /locus_tag="IXR40_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HAQ4360558.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(6885..7328)
                     /gene="rplM"
                     /locus_tag="IXR40_000688"
     CDS             complement(6885..7328)
                     /gene="rplM"
                     /locus_tag="IXR40_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HAQ4360559.1"
                     /translation="MRTTYMAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPT
                     FTPHLDTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLI
                     ETSVKGMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            complement(7847..8314)
                     /locus_tag="IXR40_000689"
     CDS             complement(7847..8314)
                     /locus_tag="IXR40_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HAQ4360560.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(8434..9972)
                     /locus_tag="IXR40_000690"
     CDS             complement(8434..9972)
                     /locus_tag="IXR40_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HAQ4360561.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            10052..10738
                     /locus_tag="IXR40_000691"
     CDS             10052..10738
                     /locus_tag="IXR40_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HAQ4360562.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(10939..11466)
                     /gene="msrA"
                     /locus_tag="IXR40_000692"
     CDS             complement(10939..11466)
                     /gene="msrA"
                     /locus_tag="IXR40_000692"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAQ4360563.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(11550..12227)
                     /gene="pgmB"
                     /locus_tag="IXR40_000693"
     CDS             complement(11550..12227)
                     /gene="pgmB"
                     /locus_tag="IXR40_000693"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HAQ4360564.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            complement(12224..13352)
                     /locus_tag="IXR40_000694"
                     /pseudo
     CDS             complement(12224..13352)
                     /locus_tag="IXR40_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
     gene            complement(13352..15535)
                     /locus_tag="IXR40_000695"
     CDS             complement(13352..15535)
                     /locus_tag="IXR40_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HAQ4360565.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(15532..16557)
                     /locus_tag="IXR40_000696"
     CDS             complement(15532..16557)
                     /locus_tag="IXR40_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAQ4360566.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTANRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            complement(16602..17429)
                     /locus_tag="IXR40_000697"
     CDS             complement(16602..17429)
                     /locus_tag="IXR40_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HAQ4360567.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(17426..18493)
                     /locus_tag="IXR40_000698"
     CDS             complement(17426..18493)
                     /locus_tag="IXR40_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HAQ4360568.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKYGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLRGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            complement(18519..19355)
                     /locus_tag="IXR40_000699"
     CDS             complement(18519..19355)
                     /locus_tag="IXR40_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAQ4360569.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(19352..20221)
                     /locus_tag="IXR40_000700"
     CDS             complement(19352..20221)
                     /locus_tag="IXR40_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAQ4360570.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(20291..21574)
                     /locus_tag="IXR40_000701"
     CDS             complement(20291..21574)
                     /locus_tag="IXR40_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAQ4360571.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(21588..23273)
                     /locus_tag="IXR40_000702"
     CDS             complement(21588..23273)
                     /locus_tag="IXR40_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphorylase"
                     /protein_id="HAQ4360572.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGARVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            23548..24573
                     /locus_tag="IXR40_000703"
     CDS             23548..24573
                     /locus_tag="IXR40_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAQ4360573.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            complement(25168..28821)
                     /gene="rpoC"
                     /locus_tag="IXR40_000704"
     CDS             complement(25168..28821)
                     /gene="rpoC"
                     /locus_tag="IXR40_000704"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HAQ4360574.1"
                     /translation="MIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYRTLKPERE
                     GLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHIELAAPVS
                     HIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTEREYREKRE
                     QYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLDILEAFRA
                     SGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLKRLLDLNA
                     PGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRFRQNLLGK
                     RVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKNAKRKIER
                     QEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVCEAYNADF
                     DGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYYLTMEEEG
                     REGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMITTVGKII
                     FNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKKKNLGNII
                     AEVFKRFKVKETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIENAHKQVET
                     ITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSGARGNISN
                     FTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTRKEVRHPE
                     TNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNLATGSDVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNPKGQAVIT
                     EVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGAPLTEGSI
                     DPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRVMDPGDTD
                     ILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAASFQETTRV
                     LTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVYSISDIEA
                     QMAAEDAMNNQTK"
     gene            complement(28900..32517)
                     /gene="rpoB"
                     /locus_tag="IXR40_000705"
     CDS             complement(28900..32517)
                     /gene="rpoB"
                     /locus_tag="IXR40_000705"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HAQ4360575.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLFALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            33245..34213
                     /locus_tag="IXR40_000706"
     CDS             33245..34213
                     /locus_tag="IXR40_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAQ4360576.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            34231..35136
                     /locus_tag="IXR40_000707"
     CDS             34231..35136
                     /locus_tag="IXR40_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4360577.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGSAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            35133..35939
                     /locus_tag="IXR40_000708"
     CDS             35133..35939
                     /locus_tag="IXR40_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAQ4360578.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            36096..37064
                     /locus_tag="IXR40_000709"
     CDS             36096..37064
                     /locus_tag="IXR40_000709"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HAQ4360579.1"
                     /translation="MTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKAIKELEKA
                     GYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMMTSESTMKDAKLAAAQGD
                     SVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTIIAASACVK
                     AIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLNFSVPQNH
                     FPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKSFVLGKTV
                     SFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(37381..37905)
                     /locus_tag="IXR40_000710"
     CDS             complement(37381..37905)
                     /locus_tag="IXR40_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DinB family protein"
                     /protein_id="HAQ4360580.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            38192..>39256
                     /gene="scm"
                     /locus_tag="IXR40_000711"
     CDS             38192..>39256
                     /gene="scm"
                     /locus_tag="IXR40_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HAQ4360581.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSS"
BASE COUNT        11246 a         8249 c         7080 g        12681 t
ORIGIN      
        1 gttctcccga acatctactg ttttgaatcc ttgactactt gtagaacttt gtacattttc
       61 tcggacatct actgtttttg gttgacttgc actgctacct tgcacattct ctcggacatc
      121 cactgattta aacccttgac tacttgtaga attttgtaca ttttctcgaa catctactgt
      181 ttttggttga cttgtactgc tactttgcag attttctcga acatcaattg tcttagtacc
      241 ttgagcattt gaagaacttt gtaaattctc tcttacatca acattccgtc caacatgacc
      301 attcagtgaa ccttgaatat tttctcggac atctactgat cggccaccat gactacttgt
      361 agaattttgt ggattttctt tgactaattt ttctaatcct gtatttgaat ttttagcttc
      421 ttgaattctt tctttggtca acgcttcttt tccgtcaata ttagcgcctg tccgcccttc
      481 tacacgtttc cttaacatta tttcctcgcg attcattgct tcaggcgtgt atttcgcttc
      541 atgacgcttc tgattaatta attcttcagc agacttagct tgaccgtgca tagcattttt
      601 acgttcttca atatcttgtt ggactttttg ctgaattgcg cttgcaggat tattattcga
      661 ttcagcatta tttttcattg cttcacgcat acgttcagaa ctagacataa ttctatcggc
      721 attttcaact ttagcaccat cttttctatc tgaaagacgt gttggcacgg aatcagcata
      781 ttttccagtt tcatcttctt tatttttagc taacataggt ttgctatttt tattaatagc
      841 ggacactgta ccatcatcta aaccttcttt aaacttattc ttggtatcat tagctatatc
      901 acgcatactc ttaaatggtt ttgttgctct ttcactagcc attgtagctc catctgaagc
      961 taaaccggat aatccacgtt catgggcata tcccaaagct cttccagttt tgccagcttt
     1021 ttttgataga gtttcgccga aattcttttc tggttttcga tcttctcctt ctccgcttcc
     1081 tttagcacga ttaaatccat ttgatccttt tctaaacagc attgcgccca ttccaaaagc
     1141 agaagcaagt tgcccatagc cttctttgag tccaatatca acaccaaagt atctcatgac
     1201 tgttccactg cctttgatta aaacaaaaac ggcacagata taagcaattg tttttataaa
     1261 aatatttgtt gagatacctt gtcctgagtt cagaaaattg ataaacatag caaacattga
     1321 taacccaaat ccttgaaacc caacagttaa gtaacattgt agaatatctg atagaacaac
     1381 ttttgaacgc tgtcctgtct caatatctgt tgcaaaaaca agaacaccta acacacgttt
     1441 aaatgcaagt tctagtattg ctgtaatgat cacaaacgcg ctgaacacat aggcgattgc
     1501 taacgctgtc aacccaattg aaatccccca tagatttgct tggtatcggt aatagcctga
     1561 tttcaagcta tcagaaaatg ttgataagaa gttgtcagaa aactttgtag caacaaattc
     1621 attattagaa ttttcaacta attcataacg aagattgtcc gcaattggat tttctttttc
     1681 caatttatca atcactttat ccgttaacac ttgtgtgaga tccgtctgtt gaaaattttt
     1741 tcgtgttaaa ttatttcgat cctccgtttt atcaatgctt gagtactgat ctgttttatt
     1801 aatatatgct aaatctgtta ctccttgttt tatcaatgac caagcgactc cgtcatctga
     1861 atttgtaatc gtagtagagt ccttataaaa tgttttagca aattgaatac cactagaaat
     1921 catggttggc attaaaagta ttaatgctat agacatcact acgttcattc caaccgattt
     1981 taaatccact gttccttttc cagtaatcat tttgtaacca acaaacatca atgaaaggat
     2041 cattaatcca atgacaattg tatttacggc tgattgataa acattattta gccctgtact
     2101 ttcaatgaaa ttgaacaaat ccagcacatc tggaatcata ttttgaatcg aatctgtcac
     2161 agtaaacatg ccttttacca cagcccatcc gagccaaatc ccgaactgac taaggaaatc
     2221 tccattgtac ttttttaggt aaggtctata aagagaatta ttcaaaaact ctgtttgact
     2281 ttttgtgtca tcaaaccaat tgaaaatact cgcatgagca atattacttg taaaaataat
     2341 catagctatc agaacaagaa aattaacaac caaccaattt atttttttat tggcaatctt
     2401 tttttcaatt attttcatcg ttacctccct tagcccattt tctgaggctc tcagagagct
     2461 tctgagccat tttttgatta attatgacat gagttacaca attatcattt tcagctctta
     2521 aatcgagaac tatagtgttg aagcaaatag tctcgattaa ttcgagacta tctgtatttt
     2581 gatctagaca ccaaacttga tctattaaac gatttttaat caaaataacc cctcctatat
     2641 tcaaagttct caaatgaagt ggagataccc ctccatttca tttgactcaa ttctattctt
     2701 attgcttatc tattccttcg ctgatttgca attcaattag ttctaacgct ttatttttta
     2761 gagaagcaaa gatataatcg tctttttgtt tgatacgatg atctgttttt gctcttcgta
     2821 tcaagtcacg taaagtcatt gatagctgtt ctctaacatg atctacaaaa tacttgttat
     2881 tacaaatttc atagataatt ttcagttgaa ttttttgttc tttttcagca gatctaatcg
     2941 catatttgaa ttttttgtac cagttgtcga attgacgata atcactattg ctagccagtt
     3001 ttaagcaatt cacaatactt tctccccata tttgtttaag aagattttct tcaataaatg
     3061 tttcgatcaa ttcttcatct aatttattat ttttagttga aagtgattca agaagatcat
     3121 cattatgtga ttctttaata tctttactat ctttataaga cttatataat tctagttcat
     3181 tttttgaact atcagcaaaa ttgtttttgt ctcttgtttt cattgatgtg tcgcatagtt
     3241 caaattttga actatcaaca gaatattgat ttgttccata gttcaaattt tgaactatca
     3301 agtttttttg tctattttct tgatgggtta tcttattaat tttataaaca tcatctttgc
     3361 acagaacagg ctttaacaaa taataaaaat ttgggaacat ttgcatttta cttttattga
     3421 agccattttt tcttttcaca agaagtttaa ctttttgaag ttcatctagt gctgataaga
     3481 ttgtattttt tgacattccc gaaatttcta cgagattttt gatttcaaat atcaaaaaaa
     3541 ttttttgatt ctcatcatac aagttatttt tcaatgaaag tctatttcta tcttttagta
     3601 acatataaac taacttagaa cttagtttca ttttcttata tttttcattt acgtttaaaa
     3661 aaataggata ttgatagtat aattctgcat atatatcaga attagaatag ccttgctttt
     3721 caactaagct ttcaacttct ttttcattca ttgtcacacc tgcttctgat tttatttgct
     3781 ataatagatt caaataaagt tttctcagaa ctttattatt gagtgttccc ccgatctgca
     3841 aactgacggg aacactcttt ttaatttttt ctacttcatc aaatttaaaa aacgaggtgt
     3901 tttttaaatt tgatgactca atatccattt tttgcattct tcttttgaaa acaactccat
     3961 tttttctaat aaaataactg gcaatcccat tcttttaaat ttcaaaaaag ttgtatatga
     4021 tacattcaaa tatttagcca tctcttttcc ttttagaaat ggtctttcta atccggtatc
     4081 aattcttgct tgatcaatag cctcttttgt catttcaaaa acataatttt tcaattgatt
     4141 cgtttgttgt ttatctaaca ttactgtaat tcctgcatcc attatttttc tcctctcatt
     4201 ttctatttct tcaatcagcc aactcgccaa gttgtattta tttagatttt caaatcatta
     4261 agtaaccaat ttaccaactt ttgataagta gatgctctaa tactttcttt gctcccattt
     4321 tcgattttga catatgtttt ccgatttata cctatcaatt ttgctgcatc gtttttagta
     4381 agtataagat cggctctatg tcttcttaag cttctaatga attgatcatt aagagttatc
     4441 attcagcgcc tcctttcaaa ttattcactt tgtggttttt atcttaataa gcacatttta
     4501 aaccacaaaa cgagtaatat caattaaaat attactcaat ttgtggtttt catgctataa
     4561 tagtttggaa tttactatag ggggcgttac tttgaataga ataaaatttt atattgattc
     4621 cagtaaaaag accattaaac aaattagtac agaaactggt attaactata caactcttac
     4681 gaactattac cgtggtgagc gaaatcctag aaatactgaa acatggaata tccttgctga
     4741 ttatttccat gttcctgtaa gttatttgat gggattagac gaaacaaatt ccatagaaca
     4801 acctaatctt gatagaataa aaactgctcg tttagaaaaa aaggacaaaa tagtcaagaa
     4861 tattgccagt cttgactcag attattttac tgaattatct aatctatact tttccatgac
     4921 ttctttactt gaagtcaaac ttcaagaaga tgactccgac tttctttttt taaaaagtat
     4981 tctagaggac tcctttgaat acacgattct atttgccaaa caaaagaagt ttattaataa
     5041 agctttaaac ttaaatatcg atgaaagaaa agagttagaa tctgagttat ttggcaactt
     5101 aacccaagta caggttaaca atctaaaaag agagataaca gctcgattaa tatcaaaact
     5161 tcaataaaac taattattca atcagccaac tcgccaagtt atcagattgg agagattagt
     5221 tatgtcaata caaaagtaca caacaaaaag cggtgcacga tatagtgtcc gcttgtatgt
     5281 tcgtaaagat gaaaatggaa agcaagaata ctatgtaaaa aaagggttta aaactgaaaa
     5341 agaagccaag ttacacgaag caagaaaaaa ggtcgagatt gaagataccg gctatcataa
     5401 gccttctaat gacttgttta taacagtgta tgaagaatgg ttgccttctt ataggaatcg
     5461 tgtacaagaa acgacatatc aacgtacaaa agaccttttc cgcttgcata tactaccaaa
     5521 attcgggaat aagtccattt ctaagattac tcctgttcac tgtcagaatg cagtcaatga
     5581 atgggcttta aaattcaaga atatcaaaca gcttaagtct tacagctctc aaatatttga
     5641 gtatgccatt tttgcagagc tattacaccg aaatcctatg gcaaatacaa atctaccaaa
     5701 gcgggaaaag aaagaaaatg aaaattactt ttcattagaa gaactaaaag ctttttggga
     5761 tattctcaat aaagaagagc ctttaaaaca tattttaatc ttccagcttt tgattactac
     5821 tggtatacgt aaaggagagc tagctgctct tcattggtct gacatttatt ttgaagaaca
     5881 gctaatgtat gttagaaaga gctatgcaac tattcgaaat gaagagaaga atgcaagaag
     5941 aaaaactgtc aggattcaaa aaaatacaaa aaatatatct tccgaacgaa tattaccaat
     6001 tgatgcacaa actattgaaa tgttaaaaat ctggaaaaaa gaacaagctc gagagctttt
     6061 gcagtttggc ataaatacaa atacaaaaaa tcaacttatc tttacctatg taaatgcaga
     6121 cggtgacatt aatcaacctt tgcatgcgga ctattcaaat aatatattga aacgtttaga
     6181 gaagaaatat aaatttaagc acgttactat tcatggattc cggcacactc acgctactct
     6241 tctactagaa ggtggagcaa gtatcaaaga aacacaagat cgattgggtc ataaaaatgc
     6301 tgaaactacc cttaacactt attctcatgt tactgaaaaa gctcaacgaa atgcgttaga
     6361 aaaattcatt gcttacactg gtttataata ttgtcattac ctttctcatt accagaacga
     6421 aaaaaagaca ccttctcgca atgagaaagt gtctgaaatc gttggtataa caacgattaa
     6481 cgttttgaaa actgtgaagc tttacgtgct ttcttaagac ctggtttttt acgttcgacc
     6541 atacgtgcgt cacgagtaag taagccagca cgtttaagag ctaaacggaa gtcaggatca
     6601 acttctagca atgcacgagc gataccatga cggatagctc ctgattgtcc agcgtatcct
     6661 ccgccgttta cgttaacaaa tacgtcatat gcgccttttg tttcagtaac agcgaaaggt
     6721 tgattgatta cttcacgcaa gtcagcatgt ggaatgtatt cttcaacatc ttttttattt
     6781 acagtaattt tgccagttcc tggtactaga cgtacgcgag caactgcgtt tttacgacgg
     6841 cctgtgccga tatattgaac ttgtgccaat gaaattccct cctattagat taagtttgtg
     6901 atgtctaaaa cttctggttg ttgtgctgca tgtggatgtt ctgctccacc gtatacgttc
     6961 aattttgtaa attgtttgcg gcctaaagtg tttttaggaa gcataccttt tacagaagtt
     7021 tcgatcaaac gacgagaatt tttagcacgc aattcgccag cagtgattga tttcaatcct
     7081 cctgggtagt tgctgtgacg gtaataaatt ttgtcagtcg cttttttacc tgttaatttc
     7141 actttgtctg cattgatgac gatgacgaaa tcgccagtat ccaaatgagg tgtgaaagtt
     7201 ggtttatttt taccacgtag tacagatgca acaactgttg aaagacgtcc caatggaaca
     7261 tcagttgcgt ctactacata ccatttacgt tctacttcgc ctggtttggc catatatgtt
     7321 gtacgcacgt tattttcctc caatttaagt tctgatgttt gacatacact tcgagtttcc
     7381 ggggctcttt gtggggcaaa caataccatt taacatatta cccgctaatc tagtcaatgt
     7441 caacgttttt ctgcttgatt gaaaaattta tatgaaactt tacttctttt ctttctttta
     7501 tataaaaggg tcgtttcctg tcaaaatgaa aaacaaaaag aggctgtgac aaaagtcttg
     7561 tcacaacccc ttattttgaa taaacggtgt tctcctgcca actcctcggt cacaagtcac
     7621 aatatccata aaacataaga agctgttttt taaaattgtt tcttgtgact cggagctgaa
     7681 cggcaggctt acaacctctt ggtaaacggt gttcaatcag ctgaccctcg gtattagctc
     7741 aaaaaacggc aaaatatgag gaactatttt gacgtttgtt tctctaatac tcaggtcaaa
     7801 acgctgattt cacaacctct ttttcggtca agttcaacaa cagtttttac gcgtcgatct
     7861 ctggcgcttt gcccaaatga gcttggatca tccagatacg tttttctgtg gctgttttga
     7921 attcgataaa gatatcttgt gttggatcgt cgccttcttc tccagaaact tcgattcctt
     7981 tttggtaaag atctgctaga taacgatagc ctgcaacaag tgtttccaaa cgttctggaa
     8041 tagtacgatc ccagcggcca atttcatcag ggatttttgt gttatctgca aattcacgca
     8101 atgtagaata aggtgaaccg tctaatgtga tcaagcgttc ggatacttca tctaactgag
     8161 cgttcaaatc atccatgaac tcatccatca ttgggtgcaa tgtaaggaaa cctggtcctc
     8221 tcatgtacca atgtgtttgg tgaacaacaa cagacatttg gcttagatct gcaactaatt
     8281 gatttaatac ttctttggtt tgttggaatt tcatctttct tgcctcctaa cattttctta
     8341 cacttaaaat aatagtagac tttcaatgaa aagtacaaca aaatcattta cctgagaacg
     8401 attttcagtt cgctttttta tccgtaaagc caatcatttt tcagaatcag ctaattcttc
     8461 tcgcagttga gcaaattgct gataagtctg tgctaaatgc ttttgtgtcg aaacaaataa
     8521 tggatagatt ttctgatatt ttttatgatc agtttcttgt actccaactt gctctttcaa
     8581 ttctatcaat tcctgtgctt cactgatact ttggatcttt ccgatgcttc tccagcctaa
     8641 aatcacagct cctaatgcgg atgcttctgt gacagtaggg aaaacaagcg ggtaacccag
     8701 tacatcagcc atcatctgac gaaaaatcgg agattgagca aacccgcctg tagcacggat
     8761 ctctgtgagc tgattttcct ggcaaactcc ttttaaaatc cgataaaggt tgagacagat
     8821 cccttctaga atcgccttca tcatttcttt ttctgtatgt tgccgctgta aaccgataaa
     8881 actgccaaac gcatctgcgt cccaaagcgg tgctcgctca ccaagtaaat agggatgaaa
     8941 aatcagacca ttggcacccg ctggcacaaa agcgatagcc gaaagcagtg catcatatgg
     9001 attttctcct ttttctttag cagattgaac gacttcctgt aaaaatgtat gccctgccca
     9061 atcaaagatg ccagcaccat tgctagtcgc tcctcccact acccaatgtt tctgatccag
     9121 aacataacaa aacgtctcca tttctggatg gaactgaggc tgagtagtaa taaaacgaag
     9181 tgctccgctc gttcctacgg tcaaagcggc gatcgtatca ccaaaagcac ctaaccctag
     9241 attagaaagc ggcccgtctg cccctcccaa aacaaatgat atatcatttg gcaaacctag
     9301 ttctgctgct gtttttgatg gtagacctgt tacttgatag gtggaaggaa agacttgcgg
     9361 caattgctct attcgaatgt tcaagtagtc aagcacttct tctgcccatt ggaattcatg
     9421 gatatcaaaa tatccagttc ctgaagctgt tccgtagtcg ctgatcagtt cgccaaacaa
     9481 tctataaaag atatagtctt tgataccgac aaaataagca gtttttttga ataattcagg
     9541 ttggctgttt tgcagccact tgattttgtt caatggtgtc attggatgaa tcggcgtccc
     9601 agtctgccga taaaattctt tgccaagcac ggtatatttc agtttttctg cttcgtccgc
     9661 tgctcggtta tctgcccaag tgatcattcg agataacggt gttttctctt catccaacaa
     9721 tatcaggcca tgcatcgcag aggagaagga gacaaattga atgattgtgt ctgaaggcaa
     9781 ctgtttaatt acttctttta taacggtgca gacaccttga aagatcaatt cctgatcttg
     9841 ttctgccatc ccttgtgttt cttggatcaa agggtagcga aaataagcgg atgctgcttc
     9901 ttgggcttca tctgtgaaag caactgcttt ggtttgtgtg gttccgatat ctaatccgat
     9961 tgaaacgttc attttttcac ctcaaatttt atgtatgtac aaaaatttag tttaagcttg
    10021 cgtatcttgg ttttgaaaag ggggagatgg cgtgttactt tattttatca ttggttgctg
    10081 tatcggatca tttttatgtt taaccgccca gcggattccg ttaggtcact ctattattta
    10141 tcctagatct cattgtgtca aatgctgtcg ttcgctttct tggtatgaat tgattccgat
    10201 tctctcgatc atcgtccaac gatttcgctg ccgctattgc aggtgtcggt tgcccttcta
    10261 ctatttgttg gcagaagcct tatgtggtgg tctttttgcc tggttcttta ctttttcttc
    10321 cgcaagaaat ttttcgacgt tcatatggat gctttcggct ttgctatttt cgttgatgga
    10381 tttattttac ttcatggtcc attctcacac gctattctgt tcttgggcaa ttttatggat
    10441 tttttggttg caggccggcg tcttccaatg gcaaagtgtg ctgttaacgt ttatcgtagg
    10501 cggtgtgtgc cttcgctatg gtcaatccta tctcggagct ggcgatactc tgttgatgct
    10561 ttcttggagt ggtggcttgt ctctagaaga gttgcttcag atcttgtttc ttgctagtct
    10621 gtttggaata tccgtttttt ctgtttactt tatctgtcat aaaaaaaagt tggaaaagct
    10681 gcctttcatt ccttttttga gcagtgcgtt gctgattgtc cttcatctta ggtattgaaa
    10741 aaaggttgtg acaaacgact tgtcacaacc tctgatatat agtgttctct taccaaatcc
    10801 ttgtgacttg gagctaggcg acaggttcac aacctctcca ctaaatggtg ttcaatcagc
    10861 tgaccctcag tattagctca aaatgctggt tttacaacct ctgatatacg gtgttccata
    10921 agtagctttt tcggcttctt atttcttgac gccccaatgt cgacgaagga aacctgcacg
    10981 tccagaacct tctcgataaa gattgtaatg gagcttgttt ttcttgtaat aatcctgatg
    11041 gtaatcttct gcaggataaa attcgcttct tggttcgatt tttgtcacga ttggcttatc
    11101 gaatcgcccg ctgtcttgca atgcttgttt tgaacgctct gcaatatttc gttcttcttc
    11161 atcattatag tagatcactg gacgataaga atcaccgcga tcagcgaact gtcctaatgc
    11221 gtcagtcgga tcggtttgct gccaatagat ttccaccaac tgatcataag aaataacttc
    11281 tggatcatat tcgatctcta ctgcttctgt atgccctgtt gtgcctgttg ttacttgttc
    11341 ataagttgga tttggtacat gcccgccagt ataaccggat gtcacagaaa tgatccctgg
    11401 ctgctcttca aatggtttga ccatacacca aaagcatccg cctgcgaaaa ctgctttttt
    11461 tgtcatataa aatccccctt ttttctcatc ataccttgat ttccaaaagg aggataacgt
    11521 tttgcttgtg acagaaaaaa cggaaactat tatatacgtg atacggcttc tgataaatgc
    11581 caaaacgaac gtacttgatc aaaaacggtt aaatcaggaa tcacatattc agcagaagga
    11641 agatttatgt tttcacctat tcccaataca tgcatgttac cagccaaagc tgcttgacaa
    11701 ccagcttctg aatcttcaat gaccaagcat gcatttggcg gtacattcaa ttgctgtgct
    11761 cctttgagaa aaacttctgg atcaggtttt gcttttgata cttgcgtgcc gtcaataagg
    11821 acatcaaaat aacttgtcaa attcgttttt tctaaaatga ggcgtgcatt tttgcttgct
    11881 gatcccaatc cgatcttgat gtttgttttt ttcaagtact caagaacagc tattgcacca
    11941 ggcaaaacgg atgtttcatc cattttttga atcgcttgaa gatatagatt gtttttttgc
    12001 tcagcaaagg ctgatttctc tttttctgag aatttctgtt ccatttttcc aaatgacagc
    12061 aatcgctcta gtgactcggt tctggatatt cctttcagtt gctcgttttc tttctcagtg
    12121 aatggaatgg acagctggtt agctaaaacc agccacgctt cgtaatgata acgagctgtg
    12181 tctacaagaa cgccatctaa atcgaatagt gctgctttga ttttcatcga ttacctcctt
    12241 gaaaatgaac gacttgaagt aaagatgcga tgtttttagc tgtgcgatga agattatcag
    12301 tggcttgctg taaagcttct tgtaaaggca cagctgcagg aaggatcgga aaaacggccg
    12361 aaatgccaac atctgctgct ttttcgcttc ctttaccaac acttccgcaa atagctatca
    12421 caggaacgcc ctctggtact cttctagcaa tcccaactgg cgcttttcct tttagacttt
    12481 gtccatctag acgtccttcg cctacgatta cgaggtctgc ttgctgtacc cgtatcgaac
    12541 tccagtaaat ccaatacgta gtcgatgcca gagactattt tccctgaagc aaatgctaac
    12601 agtcctgcac ccattccacc accagcacta ctgcccgatg cctcgattac ttgaggggca
    12661 aatctcatat aaaaatcatg catggcttgg tcagccactg ctaattcatt ttctttcaag
    12721 cctttttgtg gtccgaaaac aaaagaagcg ccttcttttc cgcataaaag attagtaaca
    12781 tcagtaatga cagtgatttt ggctttaatc agctcaatag gcacgttcgt tttatcaact
    12841 gtagcaattt tacctagatt ttctcccagt gcttctactt tttgattatc ttgatcgtaa
    12901 aaagcataac ctagaccttc tgccatgccg atgccgccat cgttggtact acttccgcca
    12961 acgccgatga tgatgtgtcg aacaccttgt tgcaacaatt gtcgtatcag ttctcctact
    13021 cctcgcgtgg ataacctaag tggctgttgt tggtttagtg ggacatcttt caatccgacg
    13081 atttctgcca tttcaaaaat cgcagtttga ccgtctgaag cgtactggat ttctttgttt
    13141 ttgccaaatg cattagtaac gactgctgtt tgccgcttca accttaaact gtctgctaat
    13201 gatgaaaccg ttccttctcc tccatcgcct ataggtagca gatcatattc agcctgaaca
    13261 aaaacttctt gaaaacctga ttgaatggct tgtgctgcct ctaaggctgt cagactttct
    13321 ttgaaagaat ctggcgcaat cagaatacgc attattttcc cctccgttcc aagatcagtt
    13381 ctttttccag ctggtattgg tctccattga caaaaatagg taatgtttct ttcgtctctt
    13441 tttttattac tatttgtttt tttgtcaaaa caaatagcaa cctgtgattt ttccaaataa
    13501 aaggaaaaga aattttttcc catgctgaag gaagtcttgg agaaatagaa agagttccat
    13561 tcgttactgt aatacctgaa aaaccaaata taactgctag ccatagtgct cctaatgaag
    13621 cagcatgaat tccgtcatct gatgaatgcg gatctggtcc taaatcaatc aggcacgctt
    13681 cttggaataa atgatacgcc cattccattt cttggatacg gcaagcctct atggcgtgaa
    13741 tcgctttact caacgatgag tcgtggattg ttttgttttc atagtaatgc aaattcttag
    13801 aaacgattgg ttgagaaaaa tactcaggta ataagtataa cagcatgaca agatctgctt
    13861 gcttgctgac ttggagttca tttacttcgc tacgggcata atcaagtaaa atagactggc
    13921 tgccaggacg ttctttgtaa gtggtcaaat caataactgg cttactgaga tacgtgtcat
    13981 cttgcggaat cagctgttct ttgttaggca ctggcaaata taacttatct aaaaaatttt
    14041 gacattcttt caaaaaaagc ggatcgccag cttgatattt aacagctaag gccacattat
    14101 aatgcgccag atagttcgta tatgcattat tgtcgatata ttctgtgtat tcatctggac
    14161 caatgactct gtgtatctct aaatgatcat cgacttttac agctctgctc agccaaaaag
    14221 ctgctgtttc atgaatgagc gtttttccct ttgtttctaa aaacgattga tcctctgttg
    14281 cttggacata ctcttgaacg gcataagcaa ggtctgcact gatatgatgt tctgcggcag
    14341 ctgaagcaac ttcttgtctt gttccggttt tgatattcaa tgcagcaaat ttgggtgtct
    14401 cttcctgacc agtgtgtgcg ctttcccatg ggaaaagtgc accttgatag tgataatctc
    14461 ttgctttttg ccgtgcgcct tctaatcgat cataacggta cagcagcaaa ttctttgcta
    14521 cttcaggaaa ctgatataaa aagaaaggca ggataaaaat ttccgtatcc cagaaaacat
    14581 gccctttata accttcgcca gttagtccct tcgcccctac actaacactt ggatcattgc
    14641 ggggagtcat aatctgtaaa tggtaagcag cgaagtccat cgctaactga tcgaaagaag
    14701 aatcgccttg gatcgttatc cgatgctgat gccaaaaatc tgtccaataa gacatcgact
    14761 gctctaaaat ttctgtataa ctaacgcttt tctgggcttg ggcaatactt ttcttaaacg
    14821 ggtctgtttg ctgaagagag gtagagagca cgatgatctt ctccagcgta aaggacgtat
    14881 tttttctgat cttttctgaa aaggaagcgg tgatccggcg attttttgct tggaatacac
    14941 ctgctttatt gaatttagct gcaatcccaa tatcaatttt actttctgtt gtctggtagg
    15001 atgcactgat caaatcgtca ccaaatactc gcagttcttt ttcaaccaac tgctgtgtac
    15061 caaaattggt ttgctgtcca tcgatacccg ttttcacatc tacttggcag tcttcggtca
    15121 acggcttgat gaccactttc agggctgcct gatggagatt attttgatca gcaacacgac
    15181 aagtaatgac ttccactttt tttccttgag cagtttcaat gagcgcatag cgtttaagct
    15241 ctcccatttc taaatctagt gcccgctcgt atgcaagaac tttcatcgtc tcaagagaaa
    15301 aatgttcacc gtcgattttt atttcccatc tgatgacatc tgggagattc actaactcgg
    15361 ctgattctgc tcctaaaggt cggttatata caccagctgc aaacattccc cttacttgat
    15421 tccgatagtc ttcctcctgg cttcctctga taccaaaaaa tccatttcca atggtcatct
    15481 gactcgcata cttattgata tactctaaat caaactgttt ttcttctact ttcataaggt
    15541 aataacttct cctgtttctg ccgaacgata taaattttcc accagattct ggatgacata
    15601 tccttgccag ccatctgcaa tcatctgagt ctggtcaccg agcgcccgat tcacaaaatg
    15661 agccatactt agttcatgtg ggtcattaac tggcgtggtc ttttgtaagg aaaccagctt
    15721 tccatctaca tcttcgaata gttcgcctgg atacagatta gcacctgcct gatcgccaca
    15781 aaaagccaca ttcagtttgt cttctctgat attcaaagca aacgaagtat tcagttggat
    15841 gatcttgccg ttttctaatt ccagtgtgcc aaaaattgca tcttctactg tgaatttgct
    15901 tggatcccat ttcccgaatt tccctgaatt ttttttcgta ccaatttttt ggaagctgta
    15961 cgcccgaacg ctttttactt taggaaatcc agtaatatac atcgctgtat caagcatgtg
    16021 aatgccataa tcgatcaaag gcccgcctcc ttgaagttct ttgtcgataa acgttcccca
    16081 gcctggaaca ccagaccgac gaagcgcatt cgcttctacg taataaatat ccccgagaac
    16141 atcaagatga ttcttgatca ttgttgcttc gtcagaaaaa cgatgctgga atccataagc
    16201 caaaatctgc ccgtttttat cggctgtctc tgccatcttt cttgcttgat cagctgtcat
    16261 agctggtggt ttctcgcaca tcactgaagc attagcttcg agggcagcca atacatgttc
    16321 gaagtgaaag cgattggctg tacagacact cacgatatcg ggagaaatct cattcagcat
    16381 ttgtgtaact gatgtatacg catgagaaaa tcctgtacgt cggcaaaagt cttctgctcg
    16441 ctggctgact ggatcaacca cagcggccaa ttctaagaca tctgatcttt tttgataata
    16501 agcagcatgt actttttctg ctacttgtcc agcgcctatg attgctactt tcttcattta
    16561 tttctctctc ctttgcttat ttacttattg ttattctttc tctattcttt ctctaaatca
    16621 tttaaatgac gcgctgtttc cagacagttt ttcaagtatt gcaatgattc ctgataaatt
    16681 ttcacttcat tttctcctcg caaacgacat tcatatacca tataaccttc atactcattt
    16741 tgaagtagcg tttgaaaatg gcgagtaaaa tcaattgcgc cagatcctgg ttggtagcga
    16801 tgattatctg ctaaatggat atgacccaca tactcttttt gcgtagtcaa tgcttttgaa
    16861 atatcatctt cttcaatatt catatgataa aaatcagcga tgatctgcac atgtttcaat
    16921 tgattagagt caatgtaatg acgcgcatcc gctaacaaat tgatcatatg gtcttggtat
    16981 cggttcaaag gctccaaata aataaccgta cctgtttctt cggctacttt atctaaataa
    17041 cgaagtgatt cgctgactgc tttatagtct ccttctttgc ttcggggtga aaccatcggc
    17101 ggtaatcgat aagtgaacat tccccaagct gctgggataa cgattccttt gcctccaacc
    17161 tcgcttagtg cacgcaaaat ctcagcaatt tgacgtacac cattaagacg ccgttcttcg
    17221 ataaagtcac cgatccaccc atcgtagccg ttacaagctg tcactactgg gatccctgtt
    17281 tctttgattg cctgtttgac tgtgtcgata ttttctatta acaacttacc gtcgatttcg
    17341 tattcttcaa atccacagtc tttgataaat ctaaattttt ctaaaatgtc tcttgggaaa
    17401 aatgcttgat cttgcgtacc gaatttcatt gttctcctcc tcggacttga acgcccattt
    17461 tgatactttc ttctgggtgc tggtctacat aacgcatgta agcttctgcg ctttctgcaa
    17521 atggcacaac tggatcaatg atttcttcac aatccaagta accgttcatc aataattccc
    17581 aacatgtgtc ctcgattcgt ttacggttcc atcttgggta atctgggttt ggttcactag
    17641 atgctcgagc aaagacgatt tttgcattat tgaaatgtgc ttcgcgacca agattaaacc
    17701 cagctggaaa aggtttagca aaggcaacat aagaaatgat cccgccatag ccgatccctc
    17761 ttaaagaagc ttgtaatgcg gcagcactgc cactcgtttc aataactgaa tctactccac
    17821 gtttatctgt caattccttt agacgaaaac cgacatctgc tttcatagga tctagcgtgt
    17881 aatcggcacc gtatttttct gctaattctc tacgctgcgc tatgggatcg atcccaacga
    17941 tggtagtagc acctgctttt ttagctaatt gaatcgcaat ttgcccgata gcgcctaaac
    18001 cgaagattgc tacagcatca cctgctcgaa catgtgcttc ccggatacca cctaaagcga
    18061 attgagcagg atcgtaacat actgcatttt tccattgatc caaccgatca agtttacgta
    18121 gtttataatt atcaacaccg tttgtaatca gcgtttcacg aatgggtcca taagtgcaga
    18181 ctaactctcc tttttgatac tctgtcacca aactgcccgt ttcttcgatc gtaccgacaa
    18241 tcatatttcc taattgaaat tcgccaaata ccacaccgcg ttggcttcct tcttctcttg
    18301 gcaagaatag gcgccattct tctgaaaatt cttcatcgat aaatggactt aatcctctaa
    18361 agtcgacaat ttctgttcct ggttttggag tagcgaaaat tactcggata cgtacttcgt
    18421 tcttttcgat ctcacggtct tcgtaatctt tgaatccggc tattcttggt tctaatgcaa
    18481 ctaatttttt catcttttct ttcctctttc ttttcttttt atccttttac gccgccttcg
    18541 actaaatcac ctttaataaa tcgttcagat aacgcataca taatgatgac tggtaaagcg
    18601 gtcaccaatg aagcggccat cattcgtccc caaatgtagt ctggtgtact gaataatgtg
    18661 ttcaaaccga ttggtaaagt aaatttttcg gaggtcgaca ggaaaatcga agcaaataaa
    18721 taatcattcc acgaaaccat aaagcaataa acgaagacag aaatgattcc agaaatagcc
    18781 aatggtataa tgatccgaat aatgatctgg atccggctaa gaccatcgat cattgctgct
    18841 tcttcaatat cagtcggaat cgtgtcaaaa taacttttta gcatgaatat cgcagtagga
    18901 agtgtttgaa cgaccatcgt gataatcagt gctgtattgg tatcatacaa acctagaccg
    18961 gaaatgattt taaataatgg aacaacgatc aaaataccgg aaaacatata aacggtgtaa
    19021 aagctagcat tgattttcga gcgagctttg aagcgtagtt ttgacaaagc gtatgccccg
    19081 ctgatcccaa tcactactgc agttacggag gctatcaagg agatcactaa actatttttg
    19141 aaatacatga tgaatggaaa aatctcagca ttgaaaatat cctgataatg ttcaaaagtc
    19201 cattctttcg gaaaaatagt ttgtgtcgtt gcaattgctt cttgtgaatc cttgaatgat
    19261 gtcatcagca tgatcaaaaa tggaaacaaa ttgacagcta atagcaacaa aatcgtcgcg
    19321 taaaataaga ttttcctgct ctttttattt ttcatttcaa gtccaccttc tttcgtgaga
    19381 gcaagacgac cgctgcaata atgatgaaca atagaatcga tatagctgct gcttttccaa
    19441 gatcattgaa cgcaaaggct gtctgataca aataaacgcc taagatattg actttattcg
    19501 tcagtagata gacatctgta aacatataga acatccagat agatcgtaaa acaatcacag
    19561 ttgctagtac tggtttgatt gccggcagtg tcacgatctt gaacttctgc caagcatttg
    19621 caccgtccat ttcagctgct tcataaagcg ttttgtcgac tgtttgcaaa atagccaaaa
    19681 atgaaataaa cgcatacgga tagtatctcc agatagcaaa caaaacgacc ataaagaagc
    19741 tagcaactgg ctggtcgaac cacagcggtg cttcgttgaa aagctgcaac ctatctacta
    19801 acagatcatt gacgattcca taactattat tgaacatata tttccaagca aaaatcaaag
    19861 aaatagatgg cgtaacataa cttaataaaa tcagtgaacg caccgttttc ctaaatctga
    19921 acttgcggtt aagcaaaata gctacggcta atcctaaagc tgtactgcct gctacaacta
    19981 agaatgtgta agcaactgtt aaacctaaag aacgataaaa ttcactatca cttaaaattt
    20041 caagataatt gcttaatccg ataaaaacgg cgtctgagtt aggattcagc ggcatatcga
    20101 aaaaactgat ctgaatattg gaaagcattg gaatcagcac taaaacagct aataaaagca
    20161 tgcttggtgc taaaagtccc atggctaatt ttaagtcaga atgtttcctt ggacgattca
    20221 ttgaaacctc cccctgataa tctgccaata gctatctact tttttcgaac accattggca
    20281 gaacttcttg ttatttcgta tttttttgtg cgtcagctaa agcttgatcg acatcttcgt
    20341 ttccgacagt tacttggttc actgcttttc cgatcacacc tgagcttgtg atatctccca
    20401 ttttcgtgaa attcttttcc ccgactagtc caaagacttg tacttcatca aaagcactag
    20461 caatctcaga tggcagctcg ccaaaagact tgatgacttc attttctttg taaccatcca
    20521 gttcgactac ttgtttattc actggttgag caccaccagg agacatcaag acccactttt
    20581 ccatgttttt cggttgagat aagaaagctg tgaatgcttc agcagcctct ttttgtttct
    20641 cgtctagacc agaagaaatc gtcaatccag atactgtgcc atagacagct tgatcttttt
    20701 gtgttgggat agcaaaaccg atattttctg agttccccgc ttcataaaca gaaggcaaaa
    20761 tgtaagttga atagattgcc attggtgctg ttccattcat gaaagcatct ttgatttctg
    20821 tcacatcatt agagcctggc atcgtgtatt gggataagtt ttgataaaac gacaatgctt
    20881 ctctcatctt ttccgtatcg atcgttacct cgccttcatc atccaaaaca tttgctccat
    20941 ttgacaaagc aaattgagag aacgcttgct cactcattgt tccttcagca gtaggcatag
    21001 caattccata ttgtttattc tctttatctg tgaaatgttg agcaattttt aaaatatcat
    21061 cccaattttc tggttctgaa aaaccagctt ctgataattt ttctttgtca taccaaatac
    21121 cttgaaccca gccgctaatt ggtgcagcaa tatagctttt tccatcttct gaacgaacaa
    21181 ggtttttggc tccgtcataa taattatctt ctccagcttc ctcgataacg ttttggactg
    21241 ccgtctgatc aatcagttca tctttatcca tcactttagc aaaatcctga ctgacttcca
    21301 ttacttctgg taatttaccg gaacgagcta acgtaacgat ttttgtattg aacgctgatt
    21361 cttctaccgg cacttgcttg attttgatgt ctggattttc tttttcaaaa tcagcaacca
    21421 gttcattgat cacacttaat cgttcctgtt cgacagaaga gtgcatgaat tgaatcgttg
    21481 tctgttgtga ttcgttagag ctttgacttt caccacaagc agtaagaaga aatccagtag
    21541 ctagcagaca ggtagtaaca ataatttttt tcattttttt ccacctctta ttttattatt
    21601 ttcagccaca tatattcata cggctggaat atcaactttc gttcttgact gcaatggata
    21661 atttgtccag aaaacaggtc taggtaatct ccttttggta aaagataacc tgctgattga
    21721 ttggaaaaat tatggataac taagactttc tcttccttcg cttcgcgaat aaaactgata
    21781 aaagaatctg ctgagtccag taagtaaatc aaactattcg gatggaaggc tttttctttt
    21841 tttcgaatag atagcatctg ggtcaattca ccatatactg ctgttcttaa tggatctgtc
    21901 tgcaactctt tctcaatatc tgctaacaaa aatttttgcc gattgatttt tcgattctct
    21961 cctgtttttt ctacgccttt gtaatcattt cgacttccca gcacactttg aatataaatt
    22021 gccggcacgc ctggtaacgt taccaaaaat gaatgagcag ctaaaaagcg tttgcttctc
    22081 cattccgtcg tatctgttgg agaacttaac gcatctagat acgtagcgtt tatctcatat
    22141 ggactggtcg ttccatctgg gtttttcttg tagtttactc gggcaccctc tttcttcagc
    22201 tgttccacta attcaaggat cgttttttcc ggcagaatac ctcgtaccgg attcaatccg
    22261 ataccgtcat gggaggctaa aaaattaaaa aaagttgttt ttttcgatgc gaaatcgatg
    22321 gtttttaacc attctttcaa cttacttgta ttacccgaac gaatcgcttg aagggtcaaa
    22381 ggtggtagcg aaaactgata gaccatctgt gcttcattct cgccattccc aaaataactg
    22441 atattatctt tgtgtggcac atttgtctca gtgatcaata ccgttcctgg agctgcttca
    22501 tcagcgattg cacggaataa ttggatgatt ttatgcgttt ctggcaggtg tatacaagaa
    22561 gttcctagtt ctttccataa aaatcccaca gcgtccaagc gaataaatga agcgcctttt
    22621 tctaagtaaa acaaaagaat atcgatcatt ttcaataaaa cttctggatt tttaaaattc
    22681 aagtctactt gatcttcgct aaaagtcgtc catacgtgtt tttctttccc gtttttgtca
    22741 atgaacgttg taagtaacgg gctggtcctt ggtctagtca cgctgcttgt atctgtatcc
    22801 agtggcaaat caataaaaaa atctttgtac gtatcattca agtttaaata ttcctgaaac
    22861 caagtacttt cggcagacat atgattgcag acaaagtcga acattaaccg tgtttcgctt
    22921 ctcatttctt ctatatcttc ccatgtgccc aaacggtcgt tgattgcctg ataatttaca
    22981 acggagaaac catcatcaga tgtatatggg aaaaatggca agaaatgtac aactctaaat
    23041 gtatctgcca aatacttttg ataaaatttc ttaaatgtac gcaaagttgg ttgctgctct
    23101 tcaaaaaatt gatccccata agtaatcaag aaaatatctt cttcgtccca atgcagtttg
    23161 cctgcctggc ctttcttctg ctgataaaca ctgacttttt gttcaatcat agaggcggtt
    23221 ttctcagaca aatctgagtc gcgataaatc gcttgtaaaa gttttgtata catcggattc
    23281 ccctttcttt tttgggagcg ttcccaacga tttgatcata ttatggaaaa cgcttactgt
    23341 caatagcatt tttttaaata attttgatat acacaaaaat acaaataaga aagcttatgt
    23401 atcaataatt aatagcttct taaaaaaata tggtctctca tgatcatgca agctattcct
    23461 aaattttcaa aatcatagac aaaaaagaat gtctattgta ctatggaatt attctaaaac
    23521 gctcccaaaa aggaggtgca tataaaattg aaacctacta tttatgacat tgcgaaaaaa
    23581 gctaatgtct caaaatcaac tgtctccaga gtattaaata accagccaaa tatctctgat
    23641 aaagcaaaag caagtgtact tcaagcaatc aaagaattga attatgaacc gagcaaaatt
    23701 gcaagaggac tgtcaggaaa tggttttgac gcgattctag cattatctca tcgtacttct
    23761 catacgacct atggcaatcc ttttttttca gatgttattc aatccatttc tgccgtttct
    23821 gaacaaaata acttcgactt gattctacaa acggcaaaaa caccagaaga agagctagaa
    23881 aaatgcgcga aaaagatcca agaaaaaatg atccgaggaa ttattatttt aagctctacg
    23941 atggatgaaa cacttctttt tgaattggat caatacaata ttcctattgt ggtaatcgga
    24001 aaagtcggaa acgactacac gaacatctac tcagtggaca cggataattt ccaggatagt
    24061 tacgatttgg tggaaacact gatcaagaat ggacaccgtc atatcggctg tctccatgct
    24121 ccgacagaag tttatgtatc caatgatcgt ctcaatggtt accgtcaatg cttatttgat
    24181 caccacctag atatccgtaa tgaatggatt atagacggcg gctttcgctt agaagatagc
    24241 atggcagcaa tgaatgattt aatgaagcta cgagaaagac caactgcgat tttttctacc
    24301 gatgcattaa aatcattgag tatttacaaa gtggcagaac aatctggaaa gcagatacct
    24361 gatgatcttt cgatcgcagg attcagtgat cccttattgt cctccctatt ttcgccacag
    24421 ttgactcgga tagacattcc gacaaatcag ttaggaatca aagccacaga acttttattc
    24481 caactaatcc accaccaata ccctgaagaa aaaagaatca ttctttcaac cgagattact
    24541 ctcacagatt cgatccaaca acaagaaatg tagaacagaa ttataaaaga acagaaacac
    24601 tgaggataag tcagttactc tgttcttttt tcaatcactc atccctcgtt accccctccc
    24661 ggtattttag cgaatttttc ttattttcca tctgttttag atagctgtgg ataactataa
    24721 tgtttgtgtt aaactatttt ttccacaggg aagaaaaaac tatttttaac cacgttgtgt
    24781 ataagttttt atagttcgtt tttttaaaca catttaccct tatttcaatc catgttattt
    24841 ggggatactt atctctaaaa cataaataga ataacagaca tgtctactgg ttttgtttta
    24901 ttcgaggaat tattcaataa tagctagcaa aatattaaaa ataaccgctc tatcttccca
    24961 tcaatttatt ttgcattcaa aaaatgatct atctttactt ttgttgattg acttctcttg
    25021 gaagatgatc gttccgatac cttaattgga tacgaaccga tgttgttaag atcctttccc
    25081 acttttcttc tagttagaca aattatttta gacaaaccaa aaaagaggtt gtgacaataa
    25141 tttgtcacaa cctctttttt aaaatatcta ttttgtttga ttgttcattg cgtcttctgc
    25201 agccatttgc gcttcaatat ctgaaatact gtagacattt tcgcttgcta caccgacttc
    25261 ttttggttcc atgtcacgat aacgttgcat accagtacca gctgggatga tcttacctat
    25321 aataacattt tctttcaaac caagaagagg atctttctta ccgcggatcg cagcatccgt
    25381 caagacacga gttgtttctt ggaatgatgc agcagataag aaactatttg tttctaatga
    25441 tgcttttgtg atacctagta agacaggtcg agaagttgca ggaacgcctc ctgagactag
    25501 cgtattgtag ttttgatctt taaagtctgc gatgtctaat aatgtacctg gtaagatatc
    25561 tgtatcacct ggatccatta cacgaacttt acgcagcatt tgacgaacca ttacttcgat
    25621 atgcttgtcg ccgatttcta ccccttgcat acggtaaaca cgttgtactt cacgaagcaa
    25681 gtagttttca acagataata catcgcgaac ttgcaacaat tgttttggat cgattgatcc
    25741 ttctgtcaat ggtgcaccac ggtggatcat atcgccttct gctactttca tacgtgctgt
    25801 ataaggaaca gtatacgtac gtgtatctgt ttttcctttg attgttactt ctttggtacg
    25861 tgttgcagga tcttctgaga tatcgatgac atcccctgtt acttctgtga tcactgcttg
    25921 ccctttcgga ttacgtgctt caaagatttc ttggacacga ggaagacctt gagtgatatc
    25981 gtctccggca accccacctg tatggaatgt acgcatcgtc aactgagtac caggttcacc
    26041 gattgattga gcggcgatcg taccaactgc ttctccgact tcaacgtcag agccagttgc
    26101 aaggttgcgt ccgtaacaat gtttgcagac accatgtttt gtattacatg tgaagacaga
    26161 acggattgtc actgtttcga cacctgcatc aacgatttgt tttgcgatgt cttcggaaat
    26221 caattggttt cctgcaatga tcaattcatt tgtttcagga tgacgtactt ctttacgggt
    26281 gtaacgtccc actaaacgat cttctaatga ttcgatgatt tcatttccct cgcggatggc
    26341 ttggatttca agacctcggt cagtaccgca atcttcttca cggatgatta catcttgggc
    26401 cacgtcaacc agacgacgag tcaagtaacc tgaatcggca gtcttcaagg ctgtatcggt
    26461 catcccttta cgagccccgt gagttgagat aaacatttcc aagacggata gtccttcacg
    26521 gaagttcgaa atgattggca attccatgat tcgaccatta ggagcggcca tcaaaccacg
    26581 cattccggca agctgtgtaa agttggaaat gttaccacga gctccagaat cagacatcat
    26641 gaagattgga tttttcgctt ccaaaccttc catcagtttt tgttggatgc tgtcttttgc
    26701 agcattccaa acagcaatga cacgttcata acgttcgtca tctgtgatca gaccacgacg
    26761 gaattgtttt gtaatagttt caacttgttt atgggcattt tcaatgattt cttgtttttc
    26821 attcagtaca ctgatgtcag cgatccctac tgtgataccg gcatgtgtcg aatgtttgta
    26881 ccctaagtct ttcatacggt caagcatctt agaagtttct tttactttga atcgtttgaa
    26941 gacttctgcg atgatgtttc ctaagttttt cttcttgaac ggtaatacta attcttgctc
    27001 tttgatatgt gcaggaatat cagtaccagc ttcaacaaag tatttgtccg gtgtttggac
    27061 ggtcaagttg aagtctgttg gttcattcag ataagggaat tcaggaggca tgatctcgtt
    27121 gaagatgatc ttaccaactg ttgtgatcat cgtacgttct ttttgccatt cagtaaatgg
    27181 tttttcacct aatgagttag ggttcacacc gatacgtgaa tgtaaatgaa catatccgtt
    27241 gcgccatgcg ataacggctt cgttttgatc tctgaagacc attccttcgc cttcgcgtcc
    27301 ttcttcttcc attgtcaagt agtagttacc tagaaccata tcttgagaag gagtaacaac
    27361 tggtttacca tctttagggt tcaagatgtt ttgagcagct aacatcaaca tacgtgcttc
    27421 tgcttgtgct tcttcattca atggaacgtg gacagccatt tggtctccat cgaaatcggc
    27481 attataagct tcacatacaa gtggatgcaa acggattgcg cgtccttgta ctaaaactgg
    27541 ttcgaatgct tggataccaa gtcggtgaag cgtaggtgcc cggttcagca atactgggtg
    27601 ttccttgatt acgtcttcta aaacatccca tacttcgtct tcttgacgtt cgattttacg
    27661 tttcgcattt ttgatgtttg aagctagttc gcgttgaaca agctcacgca tcacgaatgg
    27721 tttgaataat tcaatggcca tttcttttgg aagtccacat tggtacatct tcaagaaagg
    27781 tccaacaacg ataacggaac gacctgagta gtcgacacgt ttacctagca agttttgacg
    27841 gaaacgacct tgtttccctt tcaacatatg agaaagagat ttcaatgggc ggttacctgg
    27901 tccagtaact ggacgtccgc gacgaccgtt atcgatcaat gcatctactg cttcttgcag
    27961 catacgtttt tcattttgaa cgatgattcc aggtgcattc aagtctaaca aacgtttcaa
    28021 acggttatta cggttgatta cacgacggta aagatcattc aagtcacttg ttgcaaaacg
    28081 tccaccttct aattgaacca ttgggcgtaa atctggtgga ataacaggga taacgtccat
    28141 aaccatccag cttggttgat ttcctgaagc gcggaatgct tctaaaatat ccaaacggcg
    28201 gattgcacgt gtacgttttt gtccttgtgc agatttcaat tcttctttca attcggctgc
    28261 ttctgcatct agatcaacat tatcaagtaa ttgtttaatc gcttctgcac ccatagcagc
    28321 ttggaattct tgtccatatt gttcacgttt ttcgcgatat tcgcgttctg tcaacaattg
    28381 ttttttctct aaattcgtat ttcctggttc gatgactaca tatgaagcaa aataaatgat
    28441 ttcttccaaa gcgcgtgggc tcatgtctaa tacaagaccc atacgtgaag gaatcccttt
    28501 aaagtaccag atatgtgaaa caggagctgc taattcaata tgtcccatgc gttcacggcg
    28561 aactttcgaa cgagtaactt ccactccgca tcgatcacaa acgattcctt tataacggat
    28621 acgtttgtat tttccgcagg cacattccca gtcttttgta ggaccaaaaa tccgctcaca
    28681 gaacaaccct tcgcgttcag gttttaaggt acgatagtta atcgtctcag gtttttttac
    28741 ttcaccgtaa gaccagcttc tgattttttc gggagaagcc aaacctattt gcatactttc
    28801 gaatttattt acatcgatca aaaggggttc cctccatttc atttaatggc aaaccgcaag
    28861 acggctgatc ttcgaccgcc ttgcagctca tagaccggat tagtctaaat tatcttctgc
    28921 ggtttcaaag ttttggatga catcgtcttt ttcatcttcc acttgttcag cagctttctt
    28981 ttctaattct ttggcagttt gctgttcggc aaattttgtc aaagcatcaa cagtgatcaa
    29041 atcgtcgtct tcatcgtcca tgtcgcgaag ttcgatctct gtttcttcga tatccaagac
    29101 acgcatgtcc agacctagtg attgcaattc tttcaccaat acgcggaatg attccggtac
    29161 acctggtttt ggaattggtt cacccttgac gattgcttcg tatgttttca cacgtccgac
    29221 tacgtcatct gatttgtatg tcaagatttc ttgtaaagta taagccgcac cgtaagcttc
    29281 cagtgcccat acttccattt caccaaaacg ttgtccacca aattgagctt tacctcccaa
    29341 tggttgttgt gtaaccaatg agtaaggtcc gattgaacgt gcatgcaatt tgtcatcgac
    29401 catgtgagca agtttgatca tgtacatcac accgacagac acacgtccat caaatggttc
    29461 acctgtacgt ccgtcgtaca gaacagtttt cgcatcgctg gccataccgg cttcacgaac
    29521 tgtttcccat acgtcttcat cacttgcacc atcaaatact ggcgttgcta cgtggatacc
    29581 taactgacgt gcagccatac ccaagtgtaa ttccaatact tgcccgatgt tcatacgtga
    29641 aggcacccct aaaggattca gcatgatatc gattggtgtt ccatcaggta ggaatggcat
    29701 atcttcttcc ggcataatac gggatacaac ccctttattt ccgtgacgac cggccatttt
    29761 atccccttca tggattttac gtttttgaac gatataaaca cgaactaaca tgtttacgcc
    29821 tggtgacaat tcatctccag cttcacgagt aaagattttc acatcgtgaa cgataccgcc
    29881 gccgccatgt ggtacacgta atgatgtatc gcggacttca cgagcttttt cgccaaagat
    29941 cgcatgcaat agacgttctt ctgcagataa ttctgttacc ccttttggcg tgactttccc
    30001 tacaagcaaa tcgccatctt ggacttctgc accaatacgg atgataccca tttcgtctaa
    30061 atcttttaat gcgtcttccc cgacattagg gatttcgcgt gtgatttctt caggtcctaa
    30121 ttttgtatcg cgggcttctg attcatattc ttcaatatgg atagaagtgt atacgtcatc
    30181 ttttaccaaa cgacggctca tgatgatcgc atcttcatag ttgtaccctt cccaagtcat
    30241 gaaaccaact aaaacgtttt ggcctagagc catttcgcct tgttccatag atggtccgtc
    30301 tgccagagta tccccttttt cgactttctc acccaaatga acgattggac gttggttgta
    30361 gcttgttccg gagtttgaac gacggaattt tgttacatcg tatttatcta atgcaccgtt
    30421 gtcgcggcgt acgcggattt cagaagcatc aacgtattca acgacaccat catgtttaca
    30481 taacaaagca gctcctgagt catgcgctga tttgtattcc ataccagtac caacccatgg
    30541 tgcttgagga ttgatcaacg gcactgcttg acgctgcatg ttggcaccca tcaaggcacg
    30601 gttggagtca tcgttttcca agaaaggaat acatgctgtc gcaacggcaa ctacttgttt
    30661 aggtgatacg tccatgtagt ctactttatc aatagatact tctaagtttt cactttgagc
    30721 acgagccata acaacgtctt gagcaaatgt tccatcttca ttcaatgggc tgtttgcttg
    30781 ggctacgatg taatggtctt cgatatcagc tgtcaagtag tcgatttggt cagtaacacg
    30841 acctgtttca cggtctacac gacgataagg tgtttcgata aatccgaatt tatttacttt
    30901 cgcataactg gacaaactat tgatcaaccc gatgtttggg ccttcaggag tttcgatcgg
    30961 acacatacgg ccatagtggg agtagtgaac gtcacgaact tcataaccgg cgcggtcacg
    31021 agtcaatccg ccaggtccta aggcgaaaag acgacgtttg tgtgtcaatt cgccaagagg
    31081 gtttgtttga tccatgaact gtgacaactg agaagaacca aagaattctt tgatacttgc
    31141 cacaactgga cggatattga tcaattgttg aggtgtcaat gtttcagtat cttggatcga
    31201 cattctttca cgaaccacac gttccatacg tgctagcccg atacggaatt ggttttgtaa
    31261 aagttcaccg actgaacgga tacgacgatt tcctaagtgg tcgatatcat cgacattgcc
    31321 gataccttcc atcaagttca agaaatagct cattgaagca atgatgtcgg ctggacgaac
    31381 cgtttttaca gctgcttctg gatagccgtt tccgatcacg tttacttcac gttcagggtc
    31441 tcttggtgaa aatactttga tgacttggac agtcattgga tctgtgacca caccgtcttc
    31501 tgatggatag taagtcactg aatttaggcc attatcaatg aaaggagcta gtgtttccat
    31561 gacttggtga gtcagaactg ttcctttttc aacgatgatc tcgcctgttt ctggatcaac
    31621 taatgtttca gctaatgtca gattcaatag acgtgttttc aaatctaatt ttttgtttac
    31681 tttgtaacga ccaacgtttg ctaagtcgta acgttttgga tcgaagaaac gagcattcag
    31741 caagttacgt gagctgtctg ctgtttttgg ttcgcctgga cgcaaacgtt cgtaaacgtc
    31801 tttcaaacct tcttctgttc ttgagtcgct tgcgttttta tgcaagtctt tttcgactgt
    31861 attgcgtaat gtttcgctgt cgccgaagat ttcaaagatc gtatcatcgg aaccaaatcc
    31921 taacgcacga actaatacgg ttaaaggaat cttacgtgta cggtcgatac gtacataaga
    31981 gatgtctttt gcatcagttt ccatttctag ccaagctcca cggttaggga taacagtaga
    32041 accgaatcct tcttttccgt ttttgtcgac ttttccatgg aaatagacac ctggtgaacg
    32101 gactaactga gaaacgatta ctcgctctgc cccgttgatg atgaatgttc cttgttctgt
    32161 cattaatggg aaatcaccga agaatacttc ttgtgctttg atttcgccag tctcgcggtt
    32221 tgtcaaacgc aatgttacat gtaatggtgc agagtagttt gcatcatgcg cacgagcttc
    32281 tgctactgta tactttggtt ctttcaattc ataatctaca aattccaaag atagattgcc
    32341 attgaagtca tcgattggca aaatgtcttc aaacatttct ctaagtccct catctaagaa
    32401 ccattggtaa gagtctgttt gaatttcgat caaatttggt aattccaaca cttcactgat
    32461 tcttgcgaaa cttctacgtt cgcgatgttt tccgtatttt actacgtgtc cagccaagct
    32521 cttcacccct ctaaaatgtc attcaaaaag actacccgat caattgttac aataatattt
    32581 caaatattat ttttaggtaa caacagacat tttttgcggc ttttaggcaa aaaaaaacca
    32641 aaaatagaac attctcttga aaccttactt cgtgagcttc tacttttgtt tccttatatt
    32701 aaagccgaaa cggacaatat ttcgtttctg ccttttcttc atcagatagt ttttgcaact
    32761 tcatatacta cacttatttt ctataaaagt caacacttcc tggcgtttct tctgcttttt
    32821 cgcaacattt tcttaatgtt ttcaatttta tgttttcaat tatctgacaa ttcttaattg
    32881 acagaccttt ttatctcggt tatactttag aaaattcatt ttgtggagga acttctatgc
    32941 gaaccaacat caaccaaatc gcaccaacac aactgaataa cttttacttt agctacttta
    33001 gataggtttg tattcatcat gatggataca aacgttaaac gacagtttgt atctatgatg
    33061 gctaaagaac tttgtattgc agcaaaaagc cacgtagaca aaatgctaag tggctgagca
    33121 gtgaaaatac aaagtaaaag tatcaagcat tctacttttt caatttattt tccgactttt
    33181 caatccattt ggacattttg tctgaatgga ttttttgttt cccaaaatta aggaggaaaa
    33241 agaaatgaaa aaaaatataa tcatcggatt aggcgctgcc ctgctactag ctttaggagg
    33301 ttgcgcacaa aaagacaatt ccgcagaggc atcagatgga caaaaaacaa ttggcgtatt
    33361 gcaacttgta caacataact cgttagatgc tgcctataaa ggattcaaag aaggattagc
    33421 agaagaaggg tataaagaag gcgataatct aacaatcgat tatcaaaatg cccaaaacaa
    33481 tcaagacaac ctgaaaagta tgagtgagaa actcgtcaaa gaagatcctg atttgctact
    33541 tggaatcgcc actccagcag cacaatcttt attaaatgaa acaaccacta tcccgatgac
    33601 tgtcacagcg gtcacagact tggaacaagc ccatttagtc acatccaatg aaaaacctgg
    33661 cggcaatgtg actggcacga cagatatggt gccaatcgaa aaacaaatcg gcttactgtt
    33721 aaatatcgtg ccagacgcca aaacaatcgg catcatgtat aacaacggtg aagcaaactc
    33781 taagatccaa gctgatttgg cagaaaaaga attgaaaaaa gcgggcgtca aagtcaaagt
    33841 actgacagca aattccacaa atgatgtcca acaagtgacg aaaagtctag ctaaagatgt
    33901 agatggaatc tatattccta ctgataacac gttcgcaagt gcggcaagtg ttgtcggtga
    33961 agtcgcaaaa gaaacaaaaa cacctgtcgt tgctggcgca gttgatcaag tcaaagacgg
    34021 cggtctagca acagtaggaa tcgactacga aagcttgggc aaacaaacag ggatcatggc
    34081 agcaaaaatc ttagacggca agaatccaag tgaacttcct gtcgaaacag cgaatgattt
    34141 ggaactgtat gtcaataaag acatggccaa agcattaggc atcaatccag acagcatcaa
    34201 agaagctgaa taaaacacag gaggattctc atgacaaatt tgctctctct tttcttatca
    34261 tctgcatcgc aaggggtctt atgggcccta cttgcgattg gtgtatacgt cactttccgt
    34321 atcttggaca ttgccgactt gactgctgaa ggaagctttc ctttaggtgc agggatcgcg
    34381 gcagtaagta ttacaaatgg ctatcatcca ttgacagctt gtcttctagg ctttttaggg
    34441 agtgcggcag cagggcttgt ttccggactg cttcacacaa aattgaaaat tcccgccctt
    34501 cttgcaggga tcatcaccat gactggttta tattctgtca catcccgtgt gatgggtgcg
    34561 ccgaacatct ctttattggg tcagccaacg atctttcatt gggtcgagtc attcggcata
    34621 acaaaagaca acgctgtact gatcgtcggt ctgctttttg ctttgatcgt tgtatgttta
    34681 cttgttttgt tcttacgtac agaaacagga cttgctattc gtgcaactgg cgataatctg
    34741 gcaatgagcg aagcaaacgg gatcaacaca gataatatga agatcatcgg ttatatgatt
    34801 tctaatggat gcattgctct ttctggctcc ttgcttgcgc aaaacaacgg ctttgctgat
    34861 ttaaattctg gtattggaac gatcgtaatt ggacttgctt ctattatcat cgcagaagtt
    34921 ttgttacgta accagccact atttctccgt ctcttgactg tcgttttagg tgcggtcatt
    34981 tatcgtttta ttttagcgtt agtcttcgaa ctgaatgttg aaccaagtga ttcgaaactt
    35041 gcttctgctt tcgtgctagt gatctgtctt tctttcccgc agatccagca aaaattccat
    35101 ttacctcaaa aaaagaaagg cggtagtgtc aaatgaatga cgtcttaaca ttggaaaatc
    35161 tccatcatac ctttgaaaaa ggaacgatca acgaaaatca tgtcctgaaa ggcattaatc
    35221 tttccttaga tcccggcgac ttcgtgacga tcatcggtgg aaatggggct ggtaaatcta
    35281 ctttgctgaa cagcatcgcc ggtacatttt ctgtcgatca gggtcaaatt ttattgaatg
    35341 gaaaaaatat cacgaaaaaa tctgttgtcg aacgttcgaa atccatcagt cgcgtattcc
    35401 aagatcctaa actagggaca gccgttcgtt taacggtaga agaaaatctt gctcttgcta
    35461 tgaaacgagg aaaaaaacgc ggcttcttcc gtggtgtcaa accacaagac cgaacatttt
    35521 tcaaagacca gctggttcgg ctaaatttgg ggttggaaaa tcgtttatcc tcagaaatcg
    35581 gtttgctgtc tggaggacaa cgtcaagcta ttacgttatt gatggccaca ttacagcgtc
    35641 cagaactgat cttattagat gaacacactg cagcgcttga ccctgctact tccaaaacgg
    35701 tgatggaatt gacagaaaag ctgatcactg agcagaatct cactgctttt atggtcactc
    35761 atgacatgga agacgcgatc cgctatggga gtcgactgat catgctgcat caaggaagga
    35821 tcgtcgtaga tatccagcaa gaggaaaaac agcagctcac agtgccccaa ttattagcgt
    35881 tgttcaaaca aaacagcggc acggcattaa aagacgatca agtactttta tcttcataat
    35941 cagaaagagg atgggacaaa aaatgaacgc ccaccctctt cttttttctc tttccttctt
    36001 tcgtttttgc tttatgtatc aaccgttgtt tcttcgaaaa ctattttgtt ctctccttct
    36061 tcctgataga atggatggga aaggagcttg atgccatgac aacgaaagac aaggtacttc
    36121 aattattgaa aaagacacca gattttcttt ccggagaaaa gttggcacag caactggaag
    36181 tttcccggac aagtatttgg aaagccatca aagaattgga aaaggcaggc tatcgttttg
    36241 agcacgggcc tacagggtat cgttacctgc cctctgacgt actagatgca aaagaaatcc
    36301 agcaagagct acggtcgttt attcctgatt tgaaagtaca aacgatgatg acttctgaat
    36361 ctacgatgaa agatgccaaa ctggcagcag ctcaaggaga ttctgtttcg aagttatttg
    36421 ttgctgatac acaagaacaa gctcgtggac gttttggacg gccttttttc gctgaacctg
    36481 gacgaggaat ctacatgagt ctcttgctcc atccagacaa acggtttgat gaattgcctc
    36541 aatatacgat catcgcagcc agtgcctgtg tgaaagccat tgaatctgta accggtcgtt
    36601 ctgcttcgat caaatgggtc aatgatatct acatggatgg aaaaaaagtc tgtgggattt
    36661 tatctgaagc agtcagtgat atggaaagcg gcaggatcag tcatatcatc attgggatcg
    36721 ggcttaattt ttctgttcct caaaatcatt ttccagctga tctccaagaa aaagccatct
    36781 ctgtctttcc cgacggacaa gctagtgtca caaggaatca gctaatcagc aaaatctggc
    36841 aagaattgtt cacttatctt tctcacccag aaaaagcgtt ggacttctat aaagaaaaat
    36901 cattcgtatt gggaaaaacc gtgtcgttca atcaaaaagg aacgacttat gtcggtcttg
    36961 caaaagaaat cggtgatcat ggcgaactga tcgtccaaac aaatgaacag aagatgagtt
    37021 tgtcttctgg cgaaatcagt ctcacatcta tccgtacgca ataattatca gatttcacaa
    37081 aaggacacct gatctcatac agtgtccttt tttctgaatt ctcttcaaaa gactctcctt
    37141 attctatcag ctgacagttt ctctatcctc tagaaaaagg tattctaaaa atatctataa
    37201 agcatggtac actttcttta aatgaatcaa tgcaaaaaac aagagagtca tcagtttaca
    37261 cgatcaaaag agatagcagg ccgcttcctt tttcaatctt atagatagac catgggtaac
    37321 gataaaaaca aaaaagaact tgcgacttat tttgccgtaa gttctttttt agctagtgcc
    37381 ttaatctctt aatcccaaca aacgtctcgc atagatcacc tgaccagagt gcatagcagc
    37441 atcatcaata atagaaacga gacgcattcc tcgtgtgact ggtggtgtcc agttctcgtc
    37501 aattacttca tctagctcgg aaggttccag ccttcttaag taagaaatag caaaatcagc
    37561 agctcctcgc aagtatccta gcagatcttc tatttgatta gcttggatct gctttgcttg
    37621 ttccagacta tgcttccaat cttgttcgtt atctgctatc gtcatcggaa accggctttc
    37681 ccagtcttga ctatgccaaa ttggagaagt tcctgctaaa tcagcaatct ggaaatctaa
    37741 ttctcgagcg gtatgccaag ccagccaagt cattgatttg atctgcgggg ctctatcttc
    37801 cactggaaaa cgattggcct cctcaataga gacgccttca aacaaacgtt caaaccgatc
    37861 gtatgcccga tccacactct cgcatagcat atctaaataa tccatttatt ttcctccttt
    37921 ttatttatcc tacttacttt ttcctaattc taggatacct acttatatgt tactacacac
    37981 ccttattttt tacactttaa cagtcaccat catcaatagt ttggagattg aaagaaaaag
    38041 atagtgtcga actatcaatt gaacaagaag caacaatatg aacgtttcat taatattctt
    38101 taaataaaca atgatttttc aaacgaacag tttaagacta ggagaaaaag agtataatag
    38161 gaaaatgttt gaaaggaaag gaaggggaaa aatgaaaaaa agggcaagtt tactagtcct
    38221 agttgctttg ttgttcaata tcttttcgta tggtgtggcc gtttcagcgg aaacatacat
    38281 tcctaaagac cctgggaata tttataatga tctaactggt aactatggct tgttaggaat
    38341 tgctagtcaa ttccacgtat ttgctaaaaa taagacaact gtgaatgcac atacagacgg
    38401 aaatatagca acacatgaac ttgatgcaaa aaataatttt ggtacagagc ttcatgaagg
    38461 tttattgaac caagaaataa attatataca aaaaactgat tctttcgcta attcttcagg
    38521 catacctaca ggtagcacaa gaatgaataa atttgtcgtt ggcagtaacg tggatgtagc
    38581 acttcaagat ggtcatccta cagtcaatgg atccaggctt gatcacttaa ctccagatga
    38641 tttttataaa gatcgtgctg ggcatgaata tattgatttc gagcaggaat ttgctaaatt
    38701 gaatgtagca gcaaatgatc ttgcaacgat cactccagct aaaacatata ctgctgcaga
    38761 ttttccagac atgaacaatc ggacaatcga tttaactgat ttatcagata ccgggttttt
    38821 attggtaaat atcgatgcag aagtgttaac gatgaatacg ccacttcaaa tcattaatcc
    38881 aaatgatcaa gtagttgtat ttaatgtcat caacagttct tctgcattga acgtacagtc
    38941 accaatcaaa tacaatgatc gttcaaatca tgaaacagaa gatttttcgg atgcgaatat
    39001 ctcttggaat tttggaaatg agatgactga tttgacaatc agtgctcctt ttcaaggaac
    39061 aatccttgcg cctaatgcta ctatccgcat tactcaaaac caagacggaa cgattatagg
    39121 aacaaatgtg attttagatg cagctaccaa tcgttgggat cctaacgaaa tatttatcag
    39181 cgacaatggt acagatacga cagacacaag cgacagtaca gatacatcta ccacaagtga
    39241 tagctcagat tcatca
//
LOCUS       DACGEU010000014        38769 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.014, whole genome shotgun sequence.
ACCESSION   DACGEU010000014 DACGEU010000000
VERSION     DACGEU010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 38769)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38769)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38769
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.014"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            33..656
                     /locus_tag="IXR40_000712"
     CDS             33..656
                     /locus_tag="IXR40_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360582.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            1106..2155
                     /locus_tag="IXR40_000713"
     CDS             1106..2155
                     /locus_tag="IXR40_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAQ4360583.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            2152..3033
                     /locus_tag="IXR40_000714"
     CDS             2152..3033
                     /locus_tag="IXR40_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4360584.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            3036..3806
                     /locus_tag="IXR40_000715"
     CDS             3036..3806
                     /locus_tag="IXR40_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAQ4360585.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            4085..4939
                     /gene="aroE"
                     /locus_tag="IXR40_000716"
     CDS             4085..4939
                     /gene="aroE"
                     /locus_tag="IXR40_000716"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HAQ4360586.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            5117..6280
                     /locus_tag="IXR40_000717"
     CDS             5117..6280
                     /locus_tag="IXR40_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HAQ4360587.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGVQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            6397..6807
                     /locus_tag="IXR40_000718"
     CDS             6397..6807
                     /locus_tag="IXR40_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HAQ4360588.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            6981..9209
                     /gene="topB"
                     /locus_tag="IXR40_000719"
     CDS             6981..9209
                     /gene="topB"
                     /locus_tag="IXR40_000719"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAQ4360589.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            9347..9664
                     /locus_tag="IXR40_000720"
     CDS             9347..9664
                     /locus_tag="IXR40_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360590.1"
                     /translation="MKKVHSFLNYLMGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAY
                     SPTLILSTLTAGAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQ
                     YFG"
     gene            9824..10060
                     /locus_tag="IXR40_000721"
     CDS             9824..10060
                     /locus_tag="IXR40_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAQ4360591.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            10057..10455
                     /locus_tag="IXR40_000722"
     CDS             10057..10455
                     /locus_tag="IXR40_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HAQ4360592.1"
                     /translation="MRYLSTKEIIKINAKVILRHSPGEMIGVKDANALDMAVKQPSQA
                     VFNQELYPEIYEKAAILAINLAKKHPFHNGNKRTALVAMLLFLQLNNCPVAFSRQEAV
                     DFIIMITTSSLDFDSLKSKITSYLRQTAIK"
     gene            complement(11122..12066)
                     /locus_tag="IXR40_000723"
     CDS             complement(11122..12066)
                     /locus_tag="IXR40_000723"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HAQ4360593.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(12362..13306)
                     /locus_tag="IXR40_000724"
     CDS             complement(12362..13306)
                     /locus_tag="IXR40_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4360594.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            13527..14741
                     /locus_tag="IXR40_000725"
     CDS             13527..14741
                     /locus_tag="IXR40_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAQ4360595.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            14763..16778
                     /locus_tag="IXR40_000726"
     CDS             14763..16778
                     /locus_tag="IXR40_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HAQ4360596.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(16861..18234)
                     /locus_tag="IXR40_000727"
     CDS             complement(16861..18234)
                     /locus_tag="IXR40_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HAQ4360597.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(18260..18544)
                     /locus_tag="IXR40_000728"
     CDS             complement(18260..18544)
                     /locus_tag="IXR40_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAQ4360598.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(18546..20561)
                     /locus_tag="IXR40_000729"
     CDS             complement(18546..20561)
                     /locus_tag="IXR40_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAQ4360599.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(20740..21045)
                     /locus_tag="IXR40_000730"
     CDS             complement(20740..21045)
                     /locus_tag="IXR40_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HAQ4360600.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(21134..22165)
                     /locus_tag="IXR40_000731"
     CDS             complement(21134..22165)
                     /locus_tag="IXR40_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HAQ4360601.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            22372..23247
                     /locus_tag="IXR40_000732"
     CDS             22372..23247
                     /locus_tag="IXR40_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAQ4360602.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(23399..24241)
                     /locus_tag="IXR40_000733"
     CDS             complement(23399..24241)
                     /locus_tag="IXR40_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAQ4360603.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(24333..26210)
                     /locus_tag="IXR40_000734"
     CDS             complement(24333..26210)
                     /locus_tag="IXR40_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HAQ4360604.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(26207..27628)
                     /locus_tag="IXR40_000735"
     CDS             complement(26207..27628)
                     /locus_tag="IXR40_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HAQ4360605.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(27631..31020)
                     /locus_tag="IXR40_000736"
     CDS             complement(27631..31020)
                     /locus_tag="IXR40_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HAQ4360606.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            31277..32668
                     /locus_tag="IXR40_000737"
     CDS             31277..32668
                     /locus_tag="IXR40_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAQ4360607.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            complement(32741..33388)
                     /locus_tag="IXR40_000738"
     CDS             complement(32741..33388)
                     /locus_tag="IXR40_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAQ4360608.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(33396..34082)
                     /locus_tag="IXR40_000739"
     CDS             complement(33396..34082)
                     /locus_tag="IXR40_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4360609.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(34088..35161)
                     /locus_tag="IXR40_000740"
     CDS             complement(34088..35161)
                     /locus_tag="IXR40_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HAQ4360610.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            35383..36057
                     /locus_tag="IXR40_000741"
     CDS             35383..36057
                     /locus_tag="IXR40_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4360611.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            36062..37402
                     /locus_tag="IXR40_000742"
     CDS             36062..37402
                     /locus_tag="IXR40_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAQ4360612.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(37551..38537)
                     /locus_tag="IXR40_000743"
     CDS             complement(37551..38537)
                     /locus_tag="IXR40_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HAQ4360613.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
BASE COUNT        11942 a         7058 c         7329 g        12440 t
ORIGIN      
        1 aataaaaaat aggagaaaaa gtagaaaaga aggtgtttgt tatttgggaa gtagttaaat
       61 cgagagtaca agaaatgaat gaacatttct cagtgtcatt cgcagaaaat ccaagtaagt
      121 attttcgacg tcttgttttt ctgctcatct tatcattgct gttaacagtt gcaatgtttt
      181 tattgccgga aaaaatccga gaagagcaag taaatagtct cgtttattcg tccataccaa
      241 ccagcaaatt gaaacctttt gattacagca aagctgatca gaaaatcaaa caaagccggg
      301 cgatatcggt gatgttcagc aaaccgaacg ggaaaaccta tcaggacatg cttgatgttt
      361 ttaatgatcc tgagcttatg gaagaattga atcgaccgat cttttattat ccgatcgttt
      421 atgatgtaca tgaactggaa caaaaatata acatacgaac ggatgaagtg acatttattt
      481 tctttgatgg aggaaaagaa gcaaatcgga taactgcggg taagggagga ataactgatt
      541 ttgataagga gttgatccct gaactgaatc gacttccgtt agccaatatc aaacaattag
      601 aagaagaatt ggatagaacg ggagtaactt cccaaaattc cgagattgct aattgagaca
      661 ttggcgcgat gaaacggtgg gtctatatag cgctattttt aattatcaga acaagtgatg
      721 tttgatcttc aaaataacaa ataaaaaatt aaaaaatata gttgacgaaa ttcaaaaatt
      781 cgattagact taaatcaatt cttaaggaaa gggtgacctg taatgaactt atcaaaacgt
      841 atttcagcag aaaacaaaaa aaattggcgc agctggcgta gataagttgt attaatggtg
      901 agactttccc atagatacaa ctttttagag tgcatttcta aagcttgtat ctatgctaga
      961 catgaacatt gactgccgca tagattagaa tctatgcggt tttttgtgta aagacaatga
     1021 ccgctttggc cattgtcttt ttttgtagac tggatacttg cctgattata ataaataaaa
     1081 agattgactt tgcaggagga aaaaaatgaa aaacaaacga ttaataacag ttgtagtaat
     1141 tattttagtt tatttagcag gtgcatttat ttatggaaaa gcctcaggcg aaaaagaaag
     1201 tacttcgacg aaccagacaa aaaaaacaac agttgttggg gtattgcaat acgtgagcca
     1261 tccggcatta gatgagattt atcgaggaat caaagatggt ctgaaagaag aaggattaaa
     1321 agaaggagaa aatcttgaga tcaaatttca aaatggacaa gccgatcaga gcaagctagc
     1381 cacaatgagt caacagctag tacaatctga tccagatgcc ttgattggaa tcgcaacacc
     1441 tgccgctcaa tcattagcaa acacgacttc atcgatccca gttgtgttag gtgctgtaac
     1501 ggatcctgtg ggggctggat tagtcgcttc tttagagaaa cctggtggta atgtaacagg
     1561 tgtttctgat cagccgcctg ttacttcaca aatcaagctt gcttctgatt tgttgccaaa
     1621 tgcaaaaaaa gtcggaatct tgtatgcttc ttcagaggat aattcaaaat accaagtagc
     1681 acaagcagaa gaagctgcaa aaaaagaagg gttagaatca gtaaaatatg cggtgccttc
     1741 cactaatgag attgcacaaa cggttcaagt gatgagccga caagtcgatt ttatctatgt
     1801 tccattagat aataccattg ccaatgcgat gcaaacagtg gtaaaagaag caaacaaagc
     1861 aaatatcccc gtcattccat ctgtggatac aatggtggaa caaggtggac tagcaacaat
     1921 cgggatcaat caatatcaat tagggcttca aagcggtaag atggcggcag aacttgcgag
     1981 tggaaaagaa aaaccggaaa cgacgcctgt ttatacattt gatcaagggg atacagtgat
     2041 caatcaatct caagctgatc gcttaggaat cattgttccc caatcgatga aggaaaaagc
     2101 caaaatcatt acagatgact cgcagcaaga aacatctaag gaggatgaca aatgatcgta
     2161 tcagctattt cacaaggcat gctttgggca atattaggat tagggatttt catgacttat
     2221 cggatcttag actttcctga tatgacgaca gaagggtcct tcccattagg tgctgctgtc
     2281 tgtgtgacag ctattactca tggggtagcg ccgattgtag ctacattatt aggcgtaggt
     2341 gctggcatga tagcaggact cgttacgggg ttactttata caaaaggaaa gataccggtt
     2401 attttagcag ggattttagt gatgtcagga ttgaactcag ttattttgtt tgtgatgcga
     2461 acaccaaatc tttctttatt gaatcatccg attctacaag acagcttcca tcgctttggg
     2521 ttacctgatt actttgacac agtccttctt ggcttcatct ctttgggcat cttgattgct
     2581 gtactgctat tcttcttcaa tacagatttg ggtcaaggct atattgcgac aggagacaac
     2641 gaaacgatgg ctcggtcgtt agggataaaa accgatcgta tgaaaatttt aggtttaact
     2701 ttgtcgaacg gtgtcattgc attatccggt gcgctgattg cccagaacga cggatatgca
     2761 gatgtaaata aagggattgg cgtaatcgtc atcggtcttg cttccatcat catcggtgaa
     2821 gtgatcttcc aagaattgac gctagcagaa agattgattg ctattgttgt cggcagtatc
     2881 atttatcagc tattgatttt agtagtaatc aaactagggt ttgacacgac ttatctgaag
     2941 ttgttctccg ctatcatctt agctatttgt ctgatgatcc cgcaattgaa gaaagcactg
     3001 aacttaaaaa cgggttttga gaaggaggca tagtaatgac tgatatattg acaatcaaaa
     3061 atggcagaaa agtcgtaaac aatggaatga atgaagagaa agtactattg gatgaaatta
     3121 accttacaat cagagaaggg gacttcatca ctgtccttgg cgggaatggt gctggaaaaa
     3181 gcacactgtt caatacgatc gctggtacgc ttcaactcag tcaaggatcg atctctttta
     3241 aagatcagct gatcacaaaa gattcagaag aaaaaagagc acgattcctt tctcgagttt
     3301 tccaagaccc caagatggga acggctcctc ggatgacagt agcagaaaat ttgctacttg
     3361 cacaaaaaag aggtcaaaaa cggaaattcc gtttacgtaa cttgaaaaat caaaaagaag
     3421 attttttcag actatgtcaa gaagtcggta atggcctaga gcaacacttg gatactccag
     3481 cgggtgaatt atctggtggt caacgccaag cattaagctt gctgatggcg acgatcacag
     3541 ctcctgagtt actattatta gatgaacata ctgcagcttt agatcctaaa acagctaaag
     3601 cattaatgcg attaacaaat cagcggatca atgaacaaaa attgacttgt ctcatgatca
     3661 cgcatcgaat ggaagacgcc ttgaaatacg gaaatcgtct gatcgtactc caaaaaggga
     3721 aaatcgttca agatatttct gaaaaagaaa agcaacattt gacaatgggc gaccttttgc
     3781 agttctttga agaagtagtg gattgatttc gacagaaaaa ttcctttcag tagaaggact
     3841 tgaaaactca ttgacatctt cctttgattc atcctatact taaaacaata aacaattaaa
     3901 catatttggg tgttttgtag gatcacgtag tcaatgattt taacaattaa atagaatatt
     3961 ctttgctctg acaagtaaac gatgagaaaa gaatttgcta ctttgccacc tagacgtttc
     4021 gtactttttc gtatcaaacg ctaagtggct ttttttattg aagtaagaac aaaggaggaa
     4081 taagatgatt tctggacaaa ccaaattagc tgggctcttt gctgatccgg cttctcacag
     4141 tttatcccca ttgatgcaca atactgcttt tgaagcaaac aacatcgatg cggtgtattt
     4201 agctttccaa gtaaatccaa tgaatttgaa gcaagcagtc gaaagtattc gaacttttga
     4261 tatgttaggt gtaaatcttt cgatgccgaa taaaacagcg gttattcctt atctggatga
     4321 ggtaagccag gaagcgcaat tgatcggagc agtgaatacg atcgtgcacg aaaagggtcg
     4381 tttgattggc tataataccg atggtgcggg cttcatgcaa tccgtgcaag aagctgggat
     4441 ttcgatcaaa aagaaaaaaa tgactctact gggagctgga ggtgcagcaa aggcagtcac
     4501 tgttcaagct gcgttagacg gcgctgagga aatcgtagtt tataaacgaa acaaccaaac
     4561 attcgctcaa gtaaaagaaa cattcgaaca actcagctat cgaacttctt gtaagataaa
     4621 agttcgtgac tttgccgata cgcatcaatt aagaaaagac ttgaaagaaa gctgtcttct
     4681 agtcaatgca acagatatcg ggatgggaaa gaaaatcaat cagtcaccgc tcttagatat
     4741 aagcatgatg catgagaatc tagcggtttt tgatttgatt tatgcaccta gagaaacacg
     4801 tttattaaaa gaagcaaaaa aagtaggagc aaaaggatac aatggacttg gcatgttgat
     4861 ctaccaagga gcaatcgcgt ttgaattatg gacaaaggaa aagatgccga tccatgtgat
     4921 tgaaaagctg tttgattaaa aaaggataat agataaagat cttttattct cgcataaacg
     4981 gtctcaagaa aagtaatcct ttatgtatcg aagcatttat ttcgttattt tttattaaat
     5041 tatcaaaaaa tgataggctt ttgtcgattg gttatcgtat cctttattta tcagtaagaa
     5101 acgaggagga accacaatga gtcggatgga tcgctataag gacatccata agaaggcgaa
     5161 acctctgaag cgggatacgg ggagtatttt tgctagaaga gaacgaaaac gaacgcgtat
     5221 ggaaaatgag gaagatgcta cccgtattta tgaaagagag cagcattcat ttgaacattt
     5281 gaaccaatac gagcaacaga tatacagaga tgcaccaaga gcagaagaac aacaaaaaaa
     5341 taaaaaattt ttcaatcggc aaaagaagaa caaaccgtta aaacctcgaa gaaagcgatc
     5401 gtggaaaaaa atcattctat cgattttgct tgttttgatc ctttattcag gtatctcatt
     5461 ttttattggt aaatatgtag ctgaacatga cacaagctta gaggcagcga cttcagaaac
     5521 ctttcatggg caaaaagcga cgaatggtgc gcataatatt ttgatccttg gaagtgatac
     5581 acgcggagaa gatgccgggc gagccgatac gatcatggtc ttacagttgg atggtccttc
     5641 ccataagccg aaactgattt cttttatgcg tgacagcttc gttacgatcc caggggtagg
     5701 acaaaataag atcaattcag cttatgcata cggaggagcc gatctagtgc gtcaaacttt
     5761 agtagaaaat tttggaatcg attgtcaata ctatgcgaaa gtcgatttca aatcgtttga
     5821 aaaagtgatc gatgccttat tcatgaacgg agtgaagatc gatgcagaaa aagatctgaa
     5881 tctggatggt gtagatatta aaaaaggggt ccagaagatg gatggacatg ttcttttgca
     5941 gtacgcacgt ttccgaatgg atgaacaagg agactttggc cgtgtcagac gccaacagca
     6001 agtaatgaac gctattttca gccaattgaa gaatccattg aatctgatcc gtgcacctta
     6061 tgcagctggt aaagctttag gatatacatc cacagatgtc actgcttggt tcttgacgaa
     6121 aaacctcttt tcgattgcac gaggagctgg tggcattgat cgaataagtg tgccagtaga
     6181 cggttcgtgg aattatgggc aaagtgatta tgctggcagt attcttgaaa ttgataatca
     6241 aatgaatcaa tctgctatta cagatttttt gaataaatga tcataaaaaa gatcaagaag
     6301 aagctgcgca aggcttttgt catgaatcaa tcaaacgatt cactcgtaaa aaacgctttc
     6361 ttatggtaga tttaaccaag agaggagctg tttacattgg atatctatct gaacttcaaa
     6421 aatgagtcgc gtgaagccat cgctttttat gaaaaagttt ttcagactga agcatcaggt
     6481 atcaccacat acggtgaaat gcctggaata gaacaaatga acttgccaga agaagcaaaa
     6541 aatctaatca cgaatgcacg gctgaacatt tatgatacat tagttatgtt tgcagatacg
     6601 ccagaaggaa ttggtcctga attagttgtg ggaaataatg tttctttagt catccagaca
     6661 agaaatgaag aagaaacgaa gcgcctattt gaaagcttag ctgagggtgg taagattgag
     6721 atgccactgg atgctgttcc gtgggctcag ttgtatggga tggtaactga tcgatttggc
     6781 atcaactggc agattaacca agagtgacag ctaaagatga atattttctg gaaacatcaa
     6841 gcagcaaacg gatcatcgtt tgtttgcttg atgtttttgt gtctatttcg actatacggt
     6901 atcttttttt tattgccaga tgcgaaaata tgttccataa tagagaagtc cgcaaaaaat
     6961 taagtaacgg aggtcagaag atgaagacgg tgatactagc tgaaaaacct tcacaagcaa
     7021 aagcctatgc cgaaaccttc caacagcaaa agcggcatga agggtattat gaaatcagcg
     7081 atccattgtt tgctggtgaa gtaaccatca cttatggttt tggacatttg gtagatatgg
     7141 ttgctccagg agcttatgaa gagcgttggg caaaatggtc tttagaaaat ttgcctattt
     7201 tcccagaaac cttccgttac gaagttccaa tggacaaacg tgcacaattt tcgatcgtaa
     7261 aacgagaatt gcagtcagcc gataccatca ttattgcaac agatggtgat cgagaaggtg
     7321 aagccatcgc gtggtcgatt attcgacaag caaacgcatt ttctaaggaa aagaactatt
     7381 tacgtttatg gatcaattct cttgaaaaag aagcaatcta tgaaggtttt aagaatctcc
     7441 aacctggaaa gaactatttt ccaaaatata aagaagcgca agcaaggcag aacgctgatt
     7501 ggctgattgg aatgaatgga agtccattat atagcttgct acttcaacga aaagggattg
     7561 atggcagttt ttctcttggt cgtgtacaaa caccgacact ctatatgatt tatcagctgc
     7621 aagaagaaat caaacacttc aaaaaagaaa cgtactttga aggagaaggt ttaattacga
     7681 caaacaaagg gcagttttct ggaaaaatcg taccaaaaaa agcatttaaa acccaagaag
     7741 agttaacgaa ggaaatagaa aaacttggag cgcatttagg taagcaaaac ggacggattc
     7801 ttgaagttac gaaaaaggaa aagaggttgc atagtccacg tttattttcg ctatctagtt
     7861 tgcagacaaa gatgaatcag ctaatgaaag caagtgccaa agctacactt gatgctgctc
     7921 aaggattgta cgaaagcaag tttctaagct atccaagaac ggattccttt tacattacag
     7981 aaaatgagca tcagtatctg gttaaacatc tgcaaaatta taaaaaattt ttaggaatag
     8041 aagaagtaca gacaactgag atcaaagcaa agaaacgata tgtcgatgcg aaaaaagttc
     8101 aagaacatca tgcaattatt ccgacaaaga cgattccgac tcctgcacgc tttgcgaagc
     8161 tttccaaatt acagcaagca atctatttgc aagttttgcg cactactgtg gctatgtttg
     8221 ctgcagatta tatctacgaa gagacgaccg taatgacggg cgtacagcaa ttaaagctaa
     8281 aaagcatcgg aaagatccca ttacagcaag gttggcagga aatcttacgc atcaagtcaa
     8341 aaaagaaaga agctcagact cttcctccta tcgtagaaaa tgaagaagca gaagtagaac
     8401 tgaaaagtat ggagaaagaa acacaacctc caaaacccta taccgaagga acgttgatca
     8461 cagcaatgaa aactgcggga aaaacgctgg ataatgatga agcgcaagaa attctcaaag
     8521 aagtagaagg aatagggaca gaagctacac gagccaatat cattgaaaat cttaagcaga
     8581 agcattacat cgaagtcaat aaaaacgaaa taactgttac gccaaaagga atcactcttt
     8641 gtaaggcagt agccaatgaa ccattactga cgagcgcaga aatgactgcg cgctgggaag
     8701 ggtacttgag aaaaattggt aaacaagagg ggacaccatc tgttttttta gagaatatca
     8761 aaaaattcat cctacattta ttggcagaag ttcctaatca aatcgacaag gtagactttt
     8821 cagatgagat tagcgggaca cgtcagataa aagcgatgga gaagaaaaac gatcaattag
     8881 gaagatgtcc aaaatgtaaa aagggaatag tcatgcttta tcctaaaatc gctacatgct
     8941 tgaatccgga atgcgacttc aaattgtggc caacagtagc taaaaagaag ctgactaaaa
     9001 cgaatctcag agatttgctt tcaaaaggaa agacaagtaa agttgtcaaa ggttttactg
     9061 gtaaaaaagg gaaattcgat gcagttttag tattaaaaga agatatgaca atcggttttt
     9121 cttttccatg gatcgaaaac agtggaacaa aagcagttga tggaaacaaa gaaacatcaa
     9181 gaaaaaataa tgaaaacgaa gtagagtaaa tgaaaacaat gaaatagcgg aatatttatt
     9241 ccgaaaagtg agaatataaa taccaataaa actaaaaaat atcagtgaat caagcaaaaa
     9301 cgttggggta ggctgatttt atatagatag caaggagttt ttttatttga aaaaagtgca
     9361 ttcattttta aattatctta tgggagcaat cacgattgtg gctgtgtacc aagcatttct
     9421 aaagtatcct gattacggga cgaagttgtt gtcattgacg cacaatcaaa cagcatattc
     9481 accaacgttg attttatcga ctttgactgc aggagctaaa agcgctactt atttttttca
     9541 taaaacgaca agcatgctaa agcgaaagaa acagcgaaaa caattgttgg tggtggtagc
     9601 ggctatgatc attatttatt ttctaccagt tattacacaa gtatttcatc aatattttgg
     9661 ttaagaatac gagagtttgt gacaaaagtc atgtcacaaa cttttttctt tgtcattttt
     9721 tcgtaagaaa aagcaaaata aaagtatata cattgattaa aagtatatac ttggatataa
     9781 tgtacttact atagaatgag aatggtatag agggtggcga aatatgaaaa aaatgaaaaa
     9841 gtataaaatt agaaaatctg gcaatagcga tgtaacaact atcccaccag aagtaaaaga
     9901 attcatgggt gtgcagacag gtgacgcaat cagttatgtt tttcaatctg atggttctgt
     9961 acgaatgatc aaagcacaag aagaacctga tattgattca ttagttgatt cgatcatgaa
    10021 tcaatatgaa gacgcgttaa aagatttggt tgatttatga ggtatctttc gactaaagaa
    10081 attatcaaaa tcaacgcgaa agttatttta cgtcactcgc caggcgaaat gatcggtgta
    10141 aaagatgcaa atgcattaga tatggccgtc aaacagcctt cacaagcagt attcaatcaa
    10201 gaactctatc ctgaaatcta tgaaaaagcg gcgattttag caattaattt agctaaaaaa
    10261 catccttttc ataatggcaa taaacgaact gctcttgttg ccatgttgtt gtttcttcaa
    10321 ttgaataatt gtccagttgc tttttctcgt caagaagctg ttgattttat cataatgatt
    10381 accactagtt cattggattt cgattcacta aagtccaaga taaccagtta tttacgacaa
    10441 accgcaataa aatgaacgaa ttaaaaactt tatttctcaa ttagatcagc atgtcattaa
    10501 ggaatatgct gattttttta tgtttaatca tacaaaatag ttttttcata aaaatatgga
    10561 aaatatggat taattttgaa ataattgatt taaaaggaat acaaaagagt gaatagtagg
    10621 aaatagtggt ttagaactag tgggctgatt ttttatatat tttagtttac ataatatata
    10681 ttatacaaag tagatttaaa aaatgataaa cctctctcga acggtttttt atcaaaaatc
    10741 gtcatttttc catcaaaatc tgcttatgca aaattataaa aaaattttgc agtttttctt
    10801 actttttttg tcgtttaatt gaatgataaa aaccagtttc tttattcagt taatcaaata
    10861 tgaacgaatt agatatgaat cattgtattt gccgttgcgg aaggattttt taattaacca
    10921 cagataaaca ttgataacga ttcgcttatt gtaatcaaca gattaaattt catatgttca
    10981 tatgtacgga tacattttcg gaccgattaa ttttaaccat tctatttatt tgcttaccta
    11041 ttagatatca ataaaaaact gcttaacagc tatttcagct gttaagcagt tttaggattt
    11101 ttagttcata ttcattgttt cttataatac agtgttcaat acttctctta aagcacttgt
    11161 tgatttgctg aacattgctt tttcttcttc gttgattgat aattcaacaa cttcacgaac
    11221 accattttcg tcaacgattg atggcacacc tgtaaagata tctttttcgt cgtattcacc
    11281 agttaaataa gcagatacag gcaatacagc ttgttcgtta ttcaagatag cttttacgat
    11341 acgtgcagta ctcataccaa taccatagta agttgctttt ttacgatcaa tgatctcata
    11401 agcagcatta cggactttat cagcaatcac atctaattca tcttgggcaa tacgatggtc
    11461 tttttctaca atttcaaaca ctggtttacc accgacagtt gtatgtgacc atgcagcaac
    11521 ttctgaatca ccatgttcac ctaagatata gccgtggacg ctgcgtgggt caacttttaa
    11581 tttcaatgcg atttctttac ggaaacgagt tgtatccaat gttgttccag taccgataac
    11641 acgtgatgtt ggcagaccag attcgttcca agcgatatat gtcaaaatat ctactgggtt
    11701 tgaagcaaca acgataatac cgtcgaatcc tgatcccatg atttctttta cgatttggcg
    11761 catgattgac gcatttgttt taactaaatc taaacgagat tgaccaggtt tttggttgat
    11821 accagctgtg ataacaacga tatcagcatc tttacattct tcatagccac ctgaccatac
    11881 agccacattt tcatcgcccc aagccatacc atctaaaagg tccaatgctt ccccttctgc
    11941 tttttcttga ttcacatcga tcaatactaa ttcattagag attccttggt tgatcattgc
    12001 ataagcgata cttgttccaa caaaacctgt accgacgatt actactttac gacttgtttt
    12061 tttcatgaat aaacagctcc ttttcataac tatttgttac tttcatgaaa agtatagtct
    12121 tgtttattca ttttatcaac atgttaatta taatagttgt tattataatt tttgatggaa
    12181 acgaattcct gaatacgcat aacagataaa tgacaaatgt ttacacctat atcccctgat
    12241 aatacaacca aaagtttaga actgaaaata aatccaaaaa aattcgctgc aacgatataa
    12301 taagacagca atcgcaccta aaacaatttt ccttcatatg ctttagtgaa agattttctt
    12361 cttaatgttt atttctccat tcattgggag tacatgttga atacttcttg aataatttga
    12421 ataaagaagt cgtttgttta tatccgatac gattagcgat ttcttccaac gaaaaactcg
    12481 tttcttgaat cagttccaac gcaaagtcga attttttctt tagaaccagt tcttgaaagg
    12541 aagcatcaaa atacattttc aatttattac taagatagac cggattgtag ccaaaatgag
    12601 ctgctgtttc ttttaacgta caagaagtaa aatgcttatc gatataatct aatactctaa
    12661 gcatctcatt ttctgcgcat ccatctgctg atgaaaagct ttgttgttct aataaatgag
    12721 tcaattcgat cagtaatagt gatgtataga gatttaacga acggatctta tgactgtatg
    12781 tatcaaaata aatcaacagc atattttcaa tcaaatgcgt caaacgactt gtttttccgc
    12841 cgcgaaaatg aatgaattgt gtatgttccc ctttttcttt tgatgcattt atcaaaaaag
    12901 aagaaagtag attatttgtg cttgccaaat gattcaatat ctctgtagat aaggtttctt
    12961 cttttaataa gatgttgatt aaaatatcct cttgccctgt gtattcgatt ctttgagtag
    13021 cttctttatc aatgatcacc acgtcacttt cttccatctc tatcctttct ccattaataa
    13081 tttgtaaaca tgtaccgcta tacatataat tgatttcaac aaaatcatgt gtatgctcgg
    13141 gaacttccgc atatcgacgg tgtttactga tatgaatatt tccctgttga aatagatccc
    13201 ctcggtggat ttttggcggt gtctgaagat ggtaagctaa gtttaaatca ttgatattca
    13261 ttccttgttc acgctgcaga gtttcgattg attcttcgtt acgcaaaaaa aatgtctaat
    13321 tcagctagtt ccaattgact ccctcctttt tgtaagcggt ttctttcgct tattagttca
    13381 cgctgtactg ctattatatg caaagctatt tttggtttca taaagacttt ctatggttgg
    13441 gacatgaact tcctgtgatt ccgctattga gagaataacc acttcatact atatttttga
    13501 taagcgctta caaaaatgaa aggaacatgc ttatgaataa aaagatgatg aaattttctc
    13561 tgctgtcagt ctctcttatt ttgacttctg ctggtgcagt cacgtctgca attcccagta
    13621 tgtcagctac ttatgccacg cgttctttat ctgctgttga attattaacg actgctccct
    13681 cttttatggt cactattttt gttttgatta gtagttttat tgctaggaaa atcggacaaa
    13741 aacaaactgt gatcatcgga ttagtgattg catcgatttg tggtatcctc cccctcttct
    13801 cacaaagtta cagtattgtc ttagcttcaa gagctggact aggtattggc tttggattga
    13861 tcaattcttt ggcagtcagc atgattgctg ccttttatca cggagatgaa cgagcctcta
    13921 tgattggttt tcaaagtgca tttcaaggat ttggtgcagc tttaatgaca tttgttgcag
    13981 gacagctagt acagttcggt tggcaatata cctttttagt ctacgccatc agcttaccta
    14041 ttcttgtctt gtttgttttg tttgttccta cacctgaaac aactgaactt caatcgcatg
    14101 gcacagcccc aacaagacaa gtaatcaaaa cgaatcctaa aatgattagt tatggtattt
    14161 ttctcttgct ggtcatcgtg gtatataatg ctgtatcgat taaattagcc acagtcctga
    14221 cgacttattc tctaggaaac gaaactaatg cagcgaatat cttaacaatc atgcaattgg
    14281 caagtatggc tgccggagtt tgttttggct ggcttcagac aaaagcacat cgctatatgc
    14341 ttacactttc tttactactg atgggaatcg gctttgtatt gattgccact gtgataaacc
    14401 tgtatgtgat tgggtttggt gcgatcctaa caggaatttc tttttcgtta ttcattcctt
    14461 acttattcaa ccaagtaagt atccaagcgc ccaagtacgc ggagagtttc aatacttcaa
    14521 tcttattggt tggcgctaat ttaggtactt tcattgcacc atatggtttg ctctttctct
    14581 cttttgcttc tcttgggagt aaaacacttg ctgttttcgt caatggcagt atcttgctgt
    14641 tgattagcgc gcttattagc cttctagtag tacacaggac gaatagaaag acagtgataa
    14701 gagtagatga agaaataaaa gaacaattga caacaaaata aatttgatgg aggtcgtgta
    14761 aaatgacaaa tgaaaaacat aaagatagat ggctttggta tcctggagac tttgagatcc
    14821 gccatggact gctacaaaat ttccaacggg aagaacgagg ttttgactgg ccagcgtact
    14881 ggtacatgga tgattgccat cggaacgtca agtttaagag atattacttt cttgatcaac
    14941 cttccatgtt taaagtgacg atccaaggag ttgggtatgt agaaattaat ggacaaaaac
    15001 atccatgtgg aaaatggctg acttgtccag ctggtaaagc aaaaattcgt atctttgtag
    15061 gacatacatc agggctacca gcgatgttta tcgagggaga cgaagtaaaa tcagatattg
    15121 gctggacagc aagtaatttt attgaagaat atccagctgg ctggagtccg ctttatgtcg
    15181 atatcgcaaa agatccaaat caaatctatt atcaaaaaga atgcgtccat ccagtcactg
    15241 aaacggagat tggcggagga atcttattcg attttgggcg agcagtgaat ggctgtgtag
    15301 aactaatatc tctggatgac catatcgaat ctatcactct atgttatgga gagtccgatg
    15361 tagaagctat ggatatcgat tattgctact ataagcaaat aggaatgaca agaaaaatga
    15421 aagctcgtaa acgcgctttt cgctatttgt ttataccaga ggtttctact ggaatggttc
    15481 aacttcaagt ttttcatgaa tttttatctc tttcgaaaca agctgctttt tcaagcgatt
    15541 cttctttact gaatcagatc tggtcagtat cagaagaagc cttcaagtta tgtagtgatt
    15601 tgttttttat cgacggtatc aaacgagatc gctggatttg gtctggagat gcgtatcaat
    15661 cattcatgat caatcaatat cttttttttg acgaggaaat caataaacga acgatattag
    15721 cattaagagg acaaaatgaa atcaagcagc atatgaatac tatcgttgac tattcgatct
    15781 tgtggttgat tggtatcgaa aaccactata tgatgacgaa agactatgaa tttttacgca
    15841 tcgtctaccc taagatgcaa tcattaatga gatacttgat ggagcaaacg aatgaattag
    15901 ggtttattta tgggagagca aaagattgga tatttattga ttggtctgaa atggataaag
    15961 aaggaacgct tgctgcagaa caagtcttat tactgaaagc ctatcattcc atgatcactt
    16021 gcggagatat cttagctgaa acatatggag agaacgaaaa ttatcatact catctctatc
    16081 aagaaaaata tcaactattg aaacaaaacc tatttgacta cttttgggat gaagaacttg
    16141 gcgcttttat cgattgctat gaatctggga gaagaaatgt gacgcgtcat gcgaatattt
    16201 tcgctgtttt attcgatttt gctaacaaag accaacagca atcgatctta aagaatgtct
    16261 tattgaatga cactatcaca cagattacta ctccatattt caaattctat gaacaagatg
    16321 ctttatgcaa actcggacag acgaatatcg tctaccaaac gattcttgat tattggggag
    16381 ggatgttatc tcatgatgcg gtaactttct gggaagaata cgaccctact caaacaggaa
    16441 atgaaaagta cagtatgtat ggagatcctt atggaaaaag cttatgccat gcatggggag
    16501 caagcccaat ctatctttta ggacgctatt ttatcggttt gtatccaaca aagccaggtt
    16561 atgaagaatt tatgatacaa cctaatctag attcatttga aacactgaat tgtacgctac
    16621 ctatcaaaga tggaaagatt tcgcttgaaa aaacaaaaga taagatcgtg attacttctg
    16681 atagaacagg cggaacagtg aaaatgaatg gtaaaagtta tcctcttcta gcaaaacagc
    16741 cacttgtctt aacaagctat tcaaaaataa atgcataaaa caaaaaactg cttgcgacat
    16801 atcagaagac tttaaatctt cttctgatat tgtccaagca atttttattt tgaagtttgc
    16861 ttaattctgt tctttagaaa caatgtttgt tctttttccg gcaaaaagaa agctagataa
    16921 tacgacaagt aaaaagaaag cgatgattcc aactgtcaag gctatttgac cgtattctcc
    16981 tagtttccca agtacaagtc ctggtactag ataatcagta tcggcaaatg tagaagaagc
    17041 gattttaaga tctcctaata ctggaaggat aaataatggc agccaactaa tcaataagct
    17101 attgaaagca gaacctaata ccgcccctct tctaccgcca gtcgagttgc cgaagacacc
    17161 agaagcagct ccgcagaaga aatgtcctac taccccagga atgataactg tagtttgcaa
    17221 gcctatcata gcaaacatgg atagtgttcc tacaaagaag ctaacaaaaa agccaattaa
    17281 tacagcatta ggtgcatatg gaaaaacgat aggaacatct aatgctggtt tagaatcggg
    17341 tacgagtttt ttagcaatcc cttggaatgc tggaacgatt tctgccaaca ccattcgaac
    17401 cccttgaagg acgataacaa acccagctgt gaatgttcca gcttggatca gtgcaaagat
    17461 tacagcgttg tctccattgc ttagttctct ttcaacaaat ccaggaccag ctaacaaagc
    17521 aagtgcgaca tatacgatcg acatcaagag catgatcgat acagtagaat ctcgcaaaaa
    17581 gctgaaactt ttaggaatct ttatgtcctc tgtagaacgg tctttgtttc caaaaaactt
    17641 tccgatccat ccactagaag cataaccgat atttccggta tgccctaacg caacttgatt
    17701 gtttccagtg atgttcttca taaacggttg acaaagagca ggcgtaatag ttaatagtgt
    17761 tccttcgaag accccgccta ataagatcat ccacaaattt gcagtaaacc ccgcgcttac
    17821 taaaatgact gctgttagac aagaaacata aagcattgct tgacctgtaa gaaaaatgaa
    17881 tttatatctt gtgaatctag caagtaaaat attcacgatc atccctacta gcatgatcaa
    17941 agcagtaggt gtaccgtatt gttgcaaagc aatcgccact actgcttcat tgctaggaac
    18001 tactccttga gtatgcagag ctgtttggaa catcgaagca aaaggggtta gtgaattact
    18061 gattaaacca gcaccgccga tcagtactag gaatccgaca aatgttttga tagttccttg
    18121 gatcacttct gaaaatttct tcttctgaag aacgagacca agcagtgcaa tcaaagaaac
    18181 gaggatggag ggctgactga cgattgacac aaacaaattc aacaatttat ccattgatag
    18241 ttcctccctt gaatcatttt tattcttttg acaagatctt cgttactttt tcttttactt
    18301 cttcgctgtc aatgatcgat tgcaaaggta cgagcttttc atcaggtata gaagttagcg
    18361 tatctttcaa agaatgctca atgaagaaat aatcagccat atcgctagat acacttccaa
    18421 catccgtatg acttacttca aactcgtcca catctgctcc aagatctgca agtgcttgtt
    18481 tgatgttcat ctctaccata aaacttgttc ctaatccact ttgacatact gcaaaaattt
    18541 tcatatcatt cgtctccttt tcttatgatc gctaatattt cttcttttgt tgatgcgtgt
    18601 aataaatctt gaagattttg tttattagaa agtagctttg ttaaatttgc caaagcccga
    18661 agatgtgcct cattatcgat agcagctaaa cagatgaaca aactaatggg atgggctgga
    18721 ttatcaagca gatccacagg ttgttgaagt ttcagcaaag acatccctac ttcgtttacg
    18781 ccatcttctg gacgagcatg aggtaatgcg atgtgatcgc caatatggat aaacgcacca
    18841 tactgctcca cgcgctcgat catagctttg atataacttt cttctatttt attttctgat
    18901 aatagcggct gtgcggcaaa tgtgattgct tcttgccagt tttttggttg atccgataat
    18961 tggatcattt cttctgttaa taattcagat agcataggac gttgatcctc cttcttttct
    19021 aaaagtttgt tcattttacg atttaatact tgatagagct tttcttcgtc tacgccttct
    19081 tttaattcga tataaggcag tagcgccgac aacaattctt gggcagaagg cattgaaaat
    19141 cctggtatca gccaatctct ttgtacttga ttgatcagct gatttttttc caagtcagtc
    19201 atgattggat gcagaacata gagagacttt ttcttatcag taagtgtgag aggtacagta
    19261 gaaaaaataa tatcgtaaga agtttcgtca acctcgtgta agcggtcagc tgaattagtc
    19321 tctgtaaaaa agatcatcgg gaataattgc tgaagttcac tttttaagat caatgaagag
    19381 ctaatgccac ttggacagac gatcacggct cttatttttc tatttctttc ttctgcgtcc
    19441 gcttttctga tctctccgcc aaatagtata gtgaaaaaac caatctcttc ttcagggatg
    19501 ctcttcccta ttcgtctttc taacggaagt aatgcttttc ttgtcatttc gtagatggaa
    19561 gcatattgat gcttaatttg atcgatcatc acattaggta aataaaaaga ataggaaata
    19621 cgaaaatagg cagggaccaa gtgataaaag acattcatca ataattcacg aaacgaagca
    19681 aattctacgg ccatcaggaa ttccatgcga tggatgactt ctgaagaaca ttccagcaaa
    19741 aaatcaagtg caggctcctg gacatctcct tcaacgatcg atgctaagca aagagagaaa
    19801 aatataatct ccgaattttg atgttcggaa tagccaaggc cagtcaatac ttgtcgacta
    19861 atgtcagtga ctgcaagaga agccaacagt tcagcatctt ttaccagttc catggatgtt
    19921 tttccaattc gaatggttgt caaactcaaa taataagcta attcatccat tcgatttggt
    19981 gcgaatcgaa gatctgatag tgaaatcgtt ttatctagca aatctctaac tttggcgtaa
    20041 taatcaatgg aaagggttgc ggttaaatac gtgagcccaa atcttccagc aagtgactgc
    20101 atcaaacgag cagtgcgatt ttttgcttct cttcttaata ttgcttctga ccctagcagc
    20161 ctaaaaccag ttttcctagt atacgacagc tgacaatctt ccacttctaa ttcatttctt
    20221 atctttttga tatctgacag gactgtccct ttagaaacct gaagaaaatc ttgaaaatga
    20281 aaaacagaaa cagacgttgc agtcgaataa accatcaaat aaagaagatc tcttcgctct
    20341 tgttcggtat acacagcttc aaatcgagta atatccaaaa atttttctgc ccagtcgatt
    20401 gctcggaatt tctttatacg gatacgggta tcatccacat attcggcaaa aggagttaat
    20461 tgtttgatcg cctcgcttgt atttacttcg atgatctctg ctgctttttc tagactgatt
    20521 tctcttggtg ttttcaggag ataactaatt ttgtagttca cagcgctgtt cacctcctac
    20581 ttatattcta gtatggtagc gcttttaaat cgaggggtgt ttggtacaac ttacagttgg
    20641 atttttttta cgactgtacc gaacgatttc tatcgaatgg atacagaaaa aaagcaggtg
    20701 accaaatgtc tcctgctttt atgaattgat ttcgtccgat caatgatgat catgtttatt
    20761 ttttgaggtc agttcttcaa atttttcttt gacatcttca accgcttttt cgatatcttt
    20821 ttcaaagtga ttgggctcat taggctttgt ttcctcttct acagaatttg aaccagataa
    20881 agctgtttct ttattttctg tttcaccaga gtttgtgcca gctaatgatt cttctttgtc
    20941 ttctgtttca ccagaattag ttcctgctaa agccacttct tcttctgttt taggggccat
    21001 tgaacctctt aatcgtttgt gtttttcacc gtcataattt gtcatgttgg ttcctcctag
    21061 tagttctata ctttttcatc gtacaataag acagtttatg cgtcaaaaaa caaacccgat
    21121 tcttacaaat atgtcatatt tttccttctg attcttgaat gcttttgatt ccttcttcca
    21181 aaattttcat ttgtaagatt gtttcttcat ctttgatgac tttttctgcg ccattaacta
    21241 atgtctcgta aatcccttcg tagacacggc tgtaatcacc aacctcggaa attacttttt
    21301 cttcatgata actcccttgt tcatctatat aggtcaatac accataatgt tcgggcaaat
    21361 cgataccaaa gtcttcatga tcaggcatgt aaaacatttt cagatgttct tcttgtcgat
    21421 cttttgtttg tttcacgaac atcccttttt ttccgtaaac gacgaaactt ggacgttctt
    21481 tgatgcggaa ataactggat tttatcgaaa ttttcatatt tccatagaaa aaatccagat
    21541 cgaagtaatc attcattcgt cctttcccta aaagttgacg tacatcatag ctgatatcat
    21601 ctggttcgcc gaaataagaa agaacttgat ctactgtatg acaagcatgt ccatataaat
    21661 agctgttcgc agtagaaaat tcatgcgtat tttctggtac ttccggtctg aaataatcat
    21721 aatgcatttc tacttctaaa atatccccta attttccgct ttcgattact ttttggactg
    21781 tcaagaagtc agaatcgaac cgtctgtttt ggtaacattg gataaataga cctttttctt
    21841 ttgctaatgc aaataactct tctgcttcct ttgacgtttc tgcaaaaggt ttctctacta
    21901 gtacattctt accatgttcg agtgccattt ttccatattc ataatgaaat tgactaggtg
    21961 tagtgatgac aactaattgg atctcaggat catcccaaag atcagacagc tgatcagtat
    22021 attcgatgtc ttcgaatgtt ttccacactg gttcagatgg ggaaaaaatt tttttgatat
    22081 tgattttgtt cgtaagtttt cttgaaaaag gcaaatgata gcgatttgta ctctttccat
    22141 tgccaagata agcgattgta agcatgagtg gtgcctcctt ttattgatgt tttcagtata
    22201 tcctagaaaa gcgcagaaag tatttataat agctattctg gtaaaaaagt tcagaaaaac
    22261 acttgttatc attcggtttg gtgaaattaa tgttcaaagt aaggataaaa atcaaaaaga
    22321 tagtagcgga accaagtgtt tatcagtaag atagaatttg gaggtcagat catgcttatt
    22381 gaagaaaaac taacaaaaca agagttgttt accacgacag agaaacggat tgtcgattac
    22441 atccgtagga atatcgaagc tgcagtctac atgacgattg aagaattagc aaaagctacg
    22501 tatacttccc attcagctat cattcgttta tgcaaaaaaa tgggattcag cggatttaaa
    22561 gaattccgtt tcgagctggg gcgggaagtt catcaattga ttgctcagtt caatcaaacg
    22621 attgatccta attttccttt ttcaagtgaa gatagcactc agcaaattgc aaagaaaatg
    22681 gcggatttat cgatccagtc aataaaaaaa gcacaattgc agattgaaca tgaagattta
    22741 gatcaaatcg gtaaagtatt gaacaaggca cagcgaatct ttctttttgc aaaaggtgat
    22801 tctcaaatca cggcaaggaa attccagaat aaaatggtca agttgaataa gtttttgatc
    22861 atggctgaag aatacagtga ttcttcttgg aatgcagcca atttgactag cgaggattgc
    22921 gccattttta ttagctacag cggtcgcatc catcattatg aacgaataat gacctatttg
    22981 aagcatgtag aggcccctac cttgctgatt accggaaatc agcattcaga aatggccaaa
    23041 caggctgata tgtgtcttgt tatatcgcag gaggaatatg attttgctaa agtagcgact
    23101 ttctcctctc aaattgcctt cgattacgta ttaaatacgt tattctcagt gatatattct
    23161 caaaattttg aagagaatat ccgcaacttg aaaaacaaac aagaattgat gcaaaaaggc
    23221 cttcttaaag aatatcggaa aacttaagaa aagatcctca tttagtaata agaaagatag
    23281 tgtttgatag gctctctttg atatcatcat aaaaacaggc tgaagttttc tttttcaaac
    23341 ctcagcctgt ttgtttacgg aacgattcga atagatatat tatagaaatg aggaatagct
    23401 aacttctgtt tcttattttg aacgattgac gaaaaagata tataagaagg aggaaaatca
    23461 gtatacatgc agctaacaat ccatacagga aaaatcgttt gttctcggat actttctgta
    23521 cttctttttg aacttctttt gcatgataag gaacccggtg ccctctgaca agtaagcgat
    23581 gactgttgac catataaggt gtacaagtta ggagtgtcac gaaatcctgc cctttttcga
    23641 ttctcagatc ttttgtatca gtcggttcta ccgtcttgat ctgatcgact tgataagcga
    23701 gtgtccgtcc attgatttcg atatagaaag aatcacctaa agtcagtttc ggtaagtctg
    23761 tgaacaactt tgcttgaggc agtcctcgat ggctggaaat aacggcatgt gtattttctc
    23821 cccccgtagg ataagacgtt ccttccaata atgaggcacc tttttctagc agcacagtat
    23881 tcgtttcatc aaaaattggc aaatggacat tgatctcagg gatcgtcaaa ataccgatcg
    23941 tatgtttctc aaaataggtt ctatcctttt tcgcaggttc ttttttctta gtaaagggat
    24001 ctgcacctgg atttccacct tcttttgcta attgctggtt tttctttgtc atgttttctt
    24061 ggattttagc catgacttct tcattttctt tgaccgcttg ttgctgataa tgagagatga
    24121 tctgctgatc cagataatta ttcagcgcgt cgctaacaaa tggataagct agtatcccta
    24181 ttcctgagag aagcaagaaa agcatcagca gatctagaag tttccttttc tttggtttca
    24241 tttgtgttct ccttgtgatg actgtttgat aataaaagaa aaaggagcat ttgcgtaatc
    24301 cgctgctcct ttttccaatt cttgcaaaaa gactaaatct gactgtgctt gcgtctagca
    24361 aagtacagtc cagcaatcag tagaaggact actcctgcac cgatatacac atagattccc
    24421 ttaccgcctg ttgaaggaag tgtacctttg tgtttatttg gtattttttc aggagaaatc
    24481 aactgtcctg ctgttacata agattgttca tcgatagtaa atgctacacg gtttgttaat
    24541 ggaacatatt tttctggcgc tttcgtttct tccagatagt acgtgccata ttttagacct
    24601 gtcacatcga ttaaaccgtt acttgtggtt gtaaaaaccg ttgctgattc tttcgccgat
    24661 acccagctga cggcttttgt ggatgggtcg atcgataaat atttcgctgt gtcactatct
    24721 tgatcacgaa cgacgaattc tgctccagca agtgtttggt ctgatgtaac gtcaccatct
    24781 actttaacaa atcgtttgcc cccagtaacg acatcgactg acggtggtgt ttgatcattt
    24841 gtatgcccgt tatcgacatt tgcttggtta gaaaatcctt tggttggatc tgctttttcg
    24901 ttcaaatgca tatagtaaac gaatttcaat gtaccgccag gagttaatga aggaatataa
    24961 ttcggatcaa ctgaaaccgt gaatccgtct gtttgctcag tgacagaata atttactggg
    25021 tcgatttctt tatttccatc atataaggca taagcatacg ttcctgaaga atcattatca
    25081 aatgttaaag cagcgtcatg agtatcgata agtttgaatg ttgtgtactt gttttgcgtt
    25141 ccttctttat cagcgatacc taatgggata ttgacagaaa tctcatattg aattttttca
    25201 ccgattgcga catcttttcc attcaattga ggtgttgttt tatcaacttt agacgtatca
    25261 tttttgatgg tcttttctac tggtgtttgg ctatttgcca ggatctcaaa aggcgtgatt
    25321 gtttgctttt caatcatttc cgcattatca ggagctttta cttcttctaa attatatttt
    25381 ccaacttcta aatgattaac gatcaactgg cctttttcaa tagatgcctc ggcaaagtca
    25441 ttgttgccga tgtcataaga atgaccagta atgaaatgtt tggctttggt ttgatcagtt
    25501 gtccaagtgt acaatccatc tgtgacactt tggatgtatt ttttgacgct tggtgttcct
    25561 tcttctttag aaataataaa ttctgctcca tttagtgctt cgttttcggc agtaccgatt
    25621 tttgtaactt tcaacgttcc atcattaccg actgtatttt tagggtagag atggatagta
    25681 tctagttctt ctgtcccgta tttataagag ccatctgctt gtttgatcat ctcatataca
    25741 gggaaagcta aaaccatgtt tgcggcagct gacactccgt cttttggttc ttctttgatc
    25801 gtgtagactg catctttccc attttgtttt ttaggtaaag ataaagtgac atttccatca
    25861 gcatctgtcg ttcctgaagc aactggtgta ccaggagtca aagactggac tgcttgtttt
    25921 gctgcatcca cggacgctcc tttatctcgt tgcgcataaa attcttgagt gacgttataa
    25981 actgaaaatg aaatatcggc taatccttgg tattgatcga attcgctcat ttctttcccg
    26041 ctgttttgga ttaaaggatc gggtaaatca gtcattttct ttttatgaag gatgacttga
    26101 gctgctgtct cctctgcaaa cacttttttt gcgccgaagc tgtttgtgag taatggtaaa
    26161 ataaggaaaa ggactcctaa cataacgttt atttttttat gatttttcat tttttcactc
    26221 ctgttctttt tttgataaac aaccagattg caaagcttgc gaataccata ccaacaacgc
    26281 ctaaaagtgt atttttcgtt tcgtttgttt ttggaagaaa tggacggcta ttttcttttt
    26341 tattgactac tttcaatata ctgtccgcct ctttatcctc agaaagaaaa gttgaaatgg
    26401 taaacggaat ttctgtttca cttaaaatat aaccagaagg tgcttcgatc tcttttaatc
    26461 gataacttcc tgttttcaac ccggaaattg aaaaagcgcc atttttatcg gaaatcaggt
    26521 gaagcgcatc tgattcgttc tttgtccact tgtatccgtt ggctgtttgc tggaggtaat
    26581 ttcctgcttt gtttttaata aggaatactg cgccagctaa tcgtttatct ggtttatttg
    26641 tctcgatttt gacaaattgc ttactccctg tatatacaga gactttcttt gtactgacac
    26701 caaaaccaaa atccagtgtt ccgttgttgt tgatttcctt gttcgcctgt gctgtactgc
    26761 ttagctgcat ctgataagaa atggtcagtt tttttccagc atatttttcc aacgaaggga
    26821 tcgaaaataa aacatcaaat ccgtgaggtt tcttgtgtat gacaaagcct tctgtcagct
    26881 tttctccatt cgatgaaatc gttaaactat taggtaaaaa cgttaatgct tcatccgcac
    26941 tatctgacaa ttcgaacttt tgatagtcaa ggatatttac aggaattgtc gtatgcaagg
    27001 aataagtgat tttttcacca atcgtaaaat catttctagg ctcttctaat accttctcaa
    27061 aaggtggatc agggtagtcg ttttcttcat ttttaggata caaatggata gttgaaagtt
    27121 tttgattgtt ttgtccatgt acaggaagaa caactaccat attctctgcc ttttctttga
    27181 cgacttctgg tactttggat tcaatgaaaa gatacgcttt atctcttttt tcttgatctt
    27241 tagcggccag agaaaaagaa gcgataccat cttcgttgtt aagagttgta gttgttgctt
    27301 ctgcggtaaa cataccggaa gacgcaccgt tttttgcgat ctctgcttgt gcttcttcta
    27361 ccgttttgcc cttttcccgt agatggtaaa aagaatctgt gacatcataa acttggaatg
    27421 tgacaccatt taatcctcga tacgtttgta ataaagcttt ttcttgtccg tcatttggat
    27481 gatttttcgg cagttgcccg tttgggaaaa gcaatttgtg taaagtaatc tgaaccattt
    27541 ctgtttctgt ttctgttgct acctgagtaa aagctggttt aaatagtaac aagaagagac
    27601 acatactaag ccaaccaagt tttttcatat ttagctgccc cctctttctt ttttcaaaaa
    27661 aagataccaa atagaaaacg cacaaccaat catccctact agatagattc ctaaacggcc
    27721 aattcctccc gtttcaggta atggtacttt tgcctgattc gtgatgtcta aagaaatctg
    27781 gttgtttttg gctcctggtg acagaacaga ttcatgatct tgtccatcca cttgaattga
    27841 cccatcttcg tgtataacta tagtaactgg ctcttttaga ccttggtatc cttctggtgt
    27901 aaaagtttcg gtcagcgtat aagttccagg ttttaaattt tcgaatagaa aggtatctgt
    27961 ttcttgtcca tcttttggcg attctaagtc catttctggt ccctgcagtc tgaattttgc
    28021 tccttttaat gtctgtccgt tgtcttcttt tttgtgtacc gttagatcaa acgcttttag
    28081 tcgattttga tgagtgagcg tccatacatt atttgtcatc tcggtatttt ttcccgtgta
    28141 aatgattttt ccatatttat cgatttggaa ttcataattt cccggcgaag tatcatatcc
    28201 ggcaggacca gctgtttcaa cgactcgata tttaccaggt gtgagtgaat caaaactggc
    28261 aagacctttt tcattcgttg tttggctgtc aattggctga taagtaccat ttgcttcttt
    28321 tttctgtagg gaaaatgctg ctcctttaag atttatctct ttgtccgtcc cttgcatcgc
    28381 atacttacgt actgctacag gaacttcaac aaaaggattt tcaatagtca actggatcgt
    28441 atcatcggaa gtagtgactg tttttccatc aatggttacc gtaccatcag aagcgatctt
    28501 gatttcccaa gtagtctttt tgcttaatcc atgcccttct ggagcttttg tttctgtcag
    28561 cgtataggtc atttcttttt gcaatttgac attttctgga agagaatagg ttccgtcgcc
    28621 atgatctgtt agtaaagtat caatagaatc tcctgttaat ttgaaaacag cgccaataag
    28681 atccttttca cctgtagagg aatttttcgt tattttcaag tttaacggtg tgaattgttt
    28741 agtatttttc catgtcattg catctatttg ttgagaatcg tatcctggta caggtaattc
    28801 tttgattgtt tggtaactga atgcttgacc ttgattattg tattgaggta gtgataatat
    28861 ctcttgataa ctttctccgc tatttgcaga taatttgtca atgtctgcac gttcccacgt
    28921 atttgttgta tctttagctg gtttaatgat tcgaatatat ccgtttttcc aagctgcagc
    28981 atttgtcgta tgttcccgtt gaatctcaaa agtaacttga tctggacgat cagctagatt
    29041 gttgtcaaat tcttcccata actttttgat gtgaagactg actccgggag ctttagcaga
    29101 tggtataccg aattcagcta attcattggt atcaatgttt ggctggaaag ttgtcctgcc
    29161 gttcatttga taccagaaat ttggatggaa gtcctcattt tctgtttgga ttctcacttg
    29221 gtaatggatt tggatttctt ggtcttttcc taaatagatc tgattgctct tgatggtatt
    29281 tccttctatg gaaatagatg gagtgaccgt tgtaggactt gtccccacac tcttgactga
    29341 aagtgtacca ggctgataaa tgaatggttc tgcgattgga tcatttattt gtccattgct
    29401 tacagttgct gagatctgta cagctttttt ggctaggtat tcagagatat ctgttgcatg
    29461 atcagctgat tcatagtaaa gatcgccttt ttcatctgat gaaaccattt gtcgcatacg
    29521 agactctact tctgcttttg agagaccagc tgccggatcg ctttgaagtt ggatgccaag
    29581 accatgtatt tcgattcctc gttctttgag tgccatcgct tctccgatgg ttgcgataaa
    29641 cgtactgtcg attcttctgg atagattgtt ttggtcaggt gcatcataga ttcttgagat
    29701 tagagaagta tttcccggcc gatcttgcgt attagaaaac tgagttccgt aataattgct
    29761 gcttgattgt gcgtgtaccc gctgtacttt ataggaaaat gttggtacac catccgtcag
    29821 caaaacgatc acttttttat gtccatttgg aacggatagc atgcttcctg catctcttag
    29881 tgctttttgt gtaaaagtac caccatttgt ccgtgaaggt gtaatggatt ttacttgatt
    29941 tttcactgaa tcaaatgaac ccatctgtac tgcaccgtta ctgtagctat atccttcgct
    30001 tgagtagccg acatatccca tattgatttt gtctgtgata ccgctatctg ctaaagtatc
    30061 gacaaaacga tcgacaccaa tctttacttc accgatccga ttattgtcgt tcatacttcc
    30121 tgaccagtct acgaccaata cgagatcaag aggcgtgata tctttttgta catttccacg
    30181 agcattcaaa taaacatcaa acaatccggg tgtacttgtt tcctttgcat actttcgtat
    30241 cgcatagtct gcttgattac cggttcctcc atattcgata tacgaatggg tccgatcatt
    30301 aggatctcca ttccaagaat ttataccatc ccattgattt gttccgtttt tattgccttg
    30361 atgatcaaga acatttgtat ttcctgtagg ttgccaactg gctttaggat aagtgccctg
    30421 atcatctgtt gtatattctg taggaatcgt ttgattagat ggcacactca cagctggcaa
    30481 ggataatgta ggcaatgtaa atgggctgac agaattttcg ttttcttttg atgattcttc
    30541 ttctatttcg tctggctttg gtactgacac atctgtatct ttcttatttt ctgtctcatc
    30601 aataatgtca tattctttat tatcgacgat cagcttgttt gcctggctgt ggtaaagtgc
    30661 tggatcgatt ggaaaactca gatcgatagt ttgtttagtg tttgatgaga tttccaacgt
    30721 aattttcccg ctatttacct gataagcata gccatctcct tcttttcttt ccacatcact
    30781 taagtaattt tcgactagac caatttcttt ttctatcttt tcagcactgg tgttattcgc
    30841 atttagcttg atgttcagtg ctttttttcc agactgatcc gaaatgactt cagctgaaat
    30901 tgtttctaaa actgttggat catctgtagt gtctgctatt gcagataatg gcacaaagtt
    30961 tgataaactc aatattatca gcatgaaaat aactttcagt ttcttccctg tggtcgtcat
    31021 ttttcccctc ctttttcttt ttttctgttt tgacgtgaat agtgaaaatt attaaaataa
    31081 acaggcgtta cataatttta tttattttaa tatgataatt attatacgaa gggcgctaaa
    31141 gggaatcaca ccaattttca taccaattgg tttcatttat gaagttgatt ccttcgatta
    31201 atgagcgttt cattgaaaga aaagggttga gggagaaaaa catatgatca ggttgttgga
    31261 attaaactat agaaagatgg aaaaaatcat tcgaattctg tccatttctg acaagtggat
    31321 gactaaaaaa gaacttgcca aacgaattgg tagttcagaa tctacatttg taaggtatat
    31381 cgaagagatc aaaatccgct ggggaacgga tgtaacgatt caatcttcac aaaaattggg
    31441 gtatcgtctt gaacatttga atgtaccagc ttatttaaat gttctgatgg aaatgtcgca
    31501 aagttctaca aacagtcgtt tattaaatga gattattgtc aatccgggta aaacgattga
    31561 gtattattgt gaaaaaattt ccatcagccg gtcttctttt acacgtaagt tgaaacaatg
    31621 caatcaaatt ttagaaagct atttattaaa agtgatcgtt gaccaaggtt ttcagttaac
    31681 tagccttaaa agtgagctcc agttgcgtat ctttgttacc tttttctttt taagttacta
    31741 cggaagacgc acgttgccat ttccaatcga aaaaaagaag atcaaagaaa ttatggtcaa
    31801 gaataattgt cagatgaatt tgtttcagga agaaagccca tatgagcaat ctttctttat
    31861 tatgtatttt gttgtgcatc tcatgagaga atcccaagga actccatttg aatggaaagc
    31921 tggagactct tatgtacagt tgataaatat cgataaaaaa gacttcttaa tcttgaaaaa
    31981 tctcttagga aaattgaagt acagcagcta tataaaagta gtgaactatt ttgtcaatac
    32041 gattttttca gaattttcgg agaaagaaaa aaatgaaatc agtgagcaga tacgaaaaaa
    32101 tatgtcctac tgttcgtttt catccgctga ttgcaaagaa aaaaacgaag aatatgttgt
    32161 tcaattatta acgcaaattt attttttctc ccgtattttc ccatacgata cgactcattt
    32221 gacgatccgt gcaacttact ttgcacagca gatgcaacac cgccagatac gtctatatgc
    32281 tggatttcgt gcagaacttc aattttattc cactctactg aatcagaatc tgatttatta
    32341 tttatctagc tatatctttt ggatgcttat cggtaatcct gaaattcacc attatacttc
    32401 tgataaaaaa atactgatta tcagcgactt aagtcttcga catagtcaat atattgaaga
    32461 atatatcagt gatattcttg ctgtgcataa aattcactct gagacaactg ctattactga
    32521 agatcagctg tcgaaataca atcttctcga gtatgatctg atcgttacga atcaacccat
    32581 tttgaatgcc catgttcctc atatattgat tgatgatagt gtgtcattcg caaatgaaga
    32641 agaactcatc cgcttattcg agttatgaat aatcaaaaaa cagctatgta taaaccaccc
    32701 tgataaaaat ttcaggacaa atacacatag ctgtttcttt ttattgtatt ccttcagcaa
    32761 tccaacgaga tttatagcga aagtctttta acaactcttc ttttgtccaa ttatttgcaa
    32821 tgagatccgt caaagtgttc attacgaggg tcatggaaaa gtataggaaa ctaactgctt
    32881 cttccgacga ttgaatggag aaatgattga ttcttaataa ttccagccat ttttcgttca
    32941 ttggagaatc agccgatagt tctctacgtt tggttgtctg ctgatcattt cgctgggtta
    33001 acaagtataa cctttgccaa tagatacttt cgtgatctaa gtcgcagcac cactctaaat
    33061 atttttcgat ccccaaaaag aaatgttgtt tgttttcgct aatgaatttt aagatatctt
    33121 gatggactat gtgagaactg cttttgatcg tatacaaata agcatcttcc aaatcttgaa
    33181 aatatttata aaaagcaccg cgcgacatcc ccatcttgtc aacgatttct gagactttga
    33241 cttggctgat gtgctgtgag caaaatatct ccagtaatag gtcatcgatt ctctgtttct
    33301 ttgcgttcga taaattgaaa aaagtttctt ttggcatcca catctctcct ttatctctga
    33361 ttatacgtgg atagcccttc attgtcatga aggattcatt ccttcttttt ctcttcttct
    33421 gtcaagtacc catcttccat tcgataaacg cgatcactcc attgaatcat acggacatca
    33481 tgagtaacca taatagtcgc tttttgtttc tcatgagctt ctttaactag taatttgacg
    33541 acttcatatg catgatctgt atccaaacta gctgttggtt cgtctgctaa gatcaagctt
    33601 ggctcattat ataaagcgcg agcaattgcc actctctgtc tttctccacc agaaaggtct
    33661 ttaggataac tatttttaag tgactggata tctaaagatt gcagcaagga atcgattttt
    33721 gttgaatctt ctttttttga agtaacttgg tcaactagtt caaattgttc ctttaccgtt
    33781 aaaaaaggaa tcaaattaga gctttggaga ataaatccta tttctttaaa gcgtaaatct
    33841 gctcgttttt tttctggaag ctcagttagt gagtgaccgt tgatcactat ttctccggaa
    33901 gtcggtgttt gcaatcctcc tgaaatggta aggaaagtac ttttacctga accagaagga
    33961 ccaatgatgc tgacgaattc tccttccttt acataaaaat caattgcttt caaagctgag
    34021 acctttgtat gaccagaacc aaatgttttg gtaacttttt tcatcgttaa tatttttttc
    34081 atttttatta acctcctatt gctgtaattg ggtctacttt ggttatcgta cgtatcgaaa
    34141 acaatccgcc tagcattgcg acaatgatca aaatcccact atatagcaac cattgtgacc
    34201 aaaaaacagc aaaaggcatc gcgcttggta aaatcagact agtcaaataa gcaaacaaaa
    34261 gagcaagcag aacgcctacc accccaacaa taaaggactg tgctactaaa gatttagcga
    34321 tgaagaaatt tttgatccct tgtgctttca ttactccaaa aatagcagtc ttctgaagtg
    34381 tcatcacgta catgaaaata ccgaccacgg cagcaaccac taagaacaaa aagtatatca
    34441 tcgcatttaa ggtcatattt tgggcagaat agccaggaat actttcaatg aatgtcccaa
    34501 tagttaataa ctgtagaccc ttcgatgctt tttctttcga aattttagct gaatccttta
    34561 ttacgatccc attgatcggc tgttcttctt cagaagcaaa cggctgttgt ccatacttca
    34621 aagcagtcca cgtatctagg gacgcataga tgacgggaga aactgtgtaa taagtttcag
    34681 gaaagatacc gacaatcgtc aaaggatcgt cgtaactgcc aattttgatc gtatctccaa
    34741 ttttatagcc tgaatcagcc agattttgag agatgatgat ttcattcttt gttttaaatt
    34801 catgcccttt cgtgagtttt ggtaataaaa atgcttcttt cgttgtgccg aaaactgtaa
    34861 cattttcttt gttttttcct ttgattgctc cgctgtacaa tccgattggt gctttctctc
    34921 ctccttcaat gtatttcaga tctcctcttg ttaattgtga agctgcaaat acttgatttg
    34981 catcctccga caaaacaatc tcttgtgcgt cccaatcatc gattgctttt ttaaactctt
    35041 ctgaaagtcc attcgctagt cctgacaaca tgaatacgac atacgcaatc aagaacataa
    35101 taccgacgat caagccatat cgtaatttag aatagcgaat ttctttgata gctagaaaca
    35161 tttgtttttc ctccctatga tagattgata gtgacaaaat gtcacttgtt gaatagtgta
    35221 actctaaagt gacaatttgt cacttgtgtt gtttttttct tatcaataaa ttgtctaaga
    35281 catctttcga taaaacctta acatgagtca taaaaaattt atttaagcct tatttatgct
    35341 ttccatgata aactaaagtg accaaatcaa tgaggtggga aaatgattaa actattagta
    35401 gtagaagacg ataaagtatt atccaataat ataaaagaaa tactcgctgc aatcggcgag
    35461 ataacacaag tttatgatgg tagtgaagga ctgttcgagt tggaaagtgg agtttatgat
    35521 cttgcaatct tggatttgat gatgccggaa atgaatggat atgaagtgtt agcaaaaata
    35581 cggaaagaaa aaatacagac tccagtattg attttgactg caaaagatag tttggaagat
    35641 aagattgaag gatttgaacg aggtgcagat gattatctaa caaaaccttt ctatcgagaa
    35701 gaactgatca tgcgcgtgaa agcattattg aaacgctcgc taggtctctt tgatgaaaat
    35761 gttctgaagt ataaggatat cagttgtgat ttaaaaagca atgaagtctt gtataaagaa
    35821 caagttttgc ccatacaagg aaaagagttt gaattgctcg tttatttttt acaaaataag
    35881 ggaatcattt tgacaaaaga gcagatattt gaccggatct ggggatttga ttctgatacg
    35941 acgattacag ttattgaagt ttatatgagc aacttacgaa aacatctgcg aagtactgga
    36001 ttggataaag aaatcaaaac cttacgtaat gtcggttata tactgcaaag ggtgtgatgc
    36061 aatgaatgga gatattacac gaaagcaacg tagtcgcttt tttgcgacaa atgtagcagc
    36121 atttgctttt atcttttttc ttttgggatt cattacttta cagatattaa accaatctgc
    36181 atacagagaa acagatctgt cattagagaa aataaatttt gattctcgaa cagtacaatt
    36241 agagatacaa agatatcagc aaggcgatcc ctttttaaac ccgactcaaa cggaacaaaa
    36301 cagaacaaac atggaacagc cattaatgga accatcaaat gaccgtttta acactcaagt
    36361 gatcttgtgg tctaaaaatg gtgagatatt gaataaagca gctattggtg ggcgtttcaa
    36421 ccaaatcaaa gaattaaaaa tggatacgaa aaatctgaat accatccaaa atattgaatt
    36481 aaatgaagac agtggctcat ctgccctctc tttccgttcg attacgaaaa aagcggagac
    36541 gaatcaagat ggcgttgcct acatccaaat tttagaaaat acaaatcaaa tcaagaattc
    36601 attagcgact tttcgcacga ttatgatttt gtgtatgatt gttttttgga ttctctctat
    36661 tggtatcagt tattacttgt ctagtctaag catgcgccct attattcttt cttggagaag
    36721 acaaaaagaa tttgttgaga atgcttctca tgaattgcgc acaccgttaa cgattattca
    36781 aaatagtttg gaacatcttt ttaccaagcc taatcatact attattgaag aatccgaaag
    36841 catcgctcaa gcattgtcag agacgaggcg cctcactgga ttgacttcgg atttgctgac
    36901 aatcgctcgg aatgattctg atcagcagct gctttcaaag caaatgatca atacacaaga
    36961 atatatcgaa caacttgtta aaccatttca agagatggcc atcatagatg gaaaagagtt
    37021 tattctccat aacgatgcaa cattagaagt accaattgat gaaaaaaaaa tccatcaagt
    37081 tttggttatt ttgctggata atgcattaaa atatacgaat ccagaagata agatcatttt
    37141 ggattcatct gttaaccata aagaatggct gattcacgta aagaatactg gcccttctat
    37201 cagtgaagaa gatcaagcaa ggatttttga tcgattttat cgggaagatc aatctcgggc
    37261 gaaagagact ggcggatacg ggcttggctt ggcaattgca aaacaggtaa tcgaacagca
    37321 tcatggacag atttctgtat ccaattatct tccacaagga gtcgatttta aagtccaatt
    37381 gccgttgaag cctaaaaaat aatgcttatc cctaaaaaag ggctgtgaca aaaatcttgt
    37441 cacagccctt ttttgttgcg aataaacggt gttccagaag tagcttcttc ggaaataagc
    37501 cgaaatttct ttaagctgac cacttctgtc acaacctctt tagcttacgc ttacgatttt
    37561 ttattgcggt cttcaatgtg tacatcaccg cttgtgtcaa tatccaattc ttctcggcta
    37621 acatcttctg tcactttttc aacatcttca tgttcttctt tatgaatccc aacttcttca
    37681 cgaataactg tatgtttgct tacatctact tgctcttctt tgattgggat agtaatcgtg
    37741 tcatcttcca atttttcgtc tgttccctgt gaagattgat ctgttactgg tttgcgttcg
    37801 atgacgattt cttcacgttt gaccggtact tctaccgttt cagtatcgtt gaccacatgt
    37861 ttgtggatgt cgacttctcc agttgtcaca tcatgtgtat ttacatctaa tttttcttct
    37921 tttagttgaa ttgtatcatc atctagattt ggtttgcgat cgatgtcttc agtcttgctt
    37981 gtacccattg tatcagtctc gccaggtacg tccatcggat cagttcctgg tgtcatattc
    38041 aatggatccg ttgtattttg aaagcctgtc gtgccaccta cgtccattgg atctgttcca
    38101 gtgccagttt ctaatccagt ccccattgtg cttgctgggc taacagtatc ttgtgtatcc
    38161 attgtatctt ctgttgtttc tggctgacga tagcctttta ctgtgatgac aaattttcca
    38221 tcagaaatat ctcctctata ttgatataaa ggatcatttt ctggtgtagc cgtctcagaa
    38281 tcataggtat caaaagaaaa agtatctttt attttttccc ataaagaacg gtcttcttca
    38341 ccatccatcc gattttcatc tgtttcaaca tctataccag acaatccgtc aaatcctagt
    38401 ctagatgctg cttcatcagt agtataaata acgatatcat ctcgttcata cccttcgtta
    38461 cgcaaccgtt caattactga taatgcttct tccctcgtac tatagcttcc gatgaccgtt
    38521 aaatttttct cttccatgta aattcctcct agcaaataga tttatgattg gtatattgtt
    38581 acttataaat ttattctata ggagacgatt gttttctaca aatatttaga ttggaatttg
    38641 attaaaacaa tttaattgaa atttgaaaac atttatgtta atgaaagtca tattctaata
    38701 aaatgtcatt tgtttctata tgaattttta tgaaaaattt catataattt ccactcgttg
    38761 tgatggttt
//
LOCUS       DACGEU010000015        37169 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.015, whole genome shotgun sequence.
ACCESSION   DACGEU010000015 DACGEU010000000
VERSION     DACGEU010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 37169)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37169)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37169
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.015"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            118..1083
                     /locus_tag="IXR40_000744"
     CDS             118..1083
                     /locus_tag="IXR40_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HAQ4360614.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(1140..1370)
                     /locus_tag="IXR40_000745"
     CDS             complement(1140..1370)
                     /locus_tag="IXR40_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HAQ4360615.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(1456..2343)
                     /locus_tag="IXR40_000746"
     CDS             complement(1456..2343)
                     /locus_tag="IXR40_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HAQ4360616.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(2432..3655)
                     /locus_tag="IXR40_000747"
     CDS             complement(2432..3655)
                     /locus_tag="IXR40_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAQ4360617.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(3672..4751)
                     /locus_tag="IXR40_000748"
     CDS             complement(3672..4751)
                     /locus_tag="IXR40_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAQ4360618.1"
                     /translation="MLYYISEGGRKVKVLLYFESEKMLAKSGIGRALDHQKRALTEVG
                     ISYTLDEKEDYDILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIRSNQL
                     SPIVKKYLVGLYQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQ
                     KFREYFKLSPDQKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIR
                     KIVKEDHPENVLFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVR
                     DIPVYNGWLEDSKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEE
                     LKNVYESVLNEKVSSKLKKVNQVKD"
     gene            complement(4882..6609)
                     /gene="ptsP"
                     /locus_tag="IXR40_000749"
     CDS             complement(4882..6609)
                     /gene="ptsP"
                     /locus_tag="IXR40_000749"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HAQ4360619.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDMMEEV
                     VELVHEYVK"
     gene            complement(6609..6875)
                     /locus_tag="IXR40_000750"
     CDS             complement(6609..6875)
                     /locus_tag="IXR40_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HAQ4360620.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            7354..9588
                     /locus_tag="IXR40_000751"
     CDS             7354..9588
                     /locus_tag="IXR40_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA domain-containing protein"
                     /protein_id="HAQ4360621.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            9736..10056
                     /locus_tag="IXR40_000752"
     CDS             9736..10056
                     /locus_tag="IXR40_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HAQ4360622.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
     gene            complement(10261..10485)
                     /locus_tag="IXR40_000753"
     CDS             complement(10261..10485)
                     /locus_tag="IXR40_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HAQ4360623.1"
                     /translation="METEWQRRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
     gene            complement(10683..12263)
                     /locus_tag="IXR40_000754"
     CDS             complement(10683..12263)
                     /locus_tag="IXR40_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HAQ4360624.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(12664..14040)
                     /locus_tag="IXR40_000755"
     CDS             complement(12664..14040)
                     /locus_tag="IXR40_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010767236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HAQ4360625.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(14168..15286)
                     /locus_tag="IXR40_000756"
     CDS             complement(14168..15286)
                     /locus_tag="IXR40_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAQ4360626.1"
                     /translation="MFEKLRQSKLMFWSLELLIIAALIMISSEINFIFEPIGTFFSTL
                     FAPVLIAGFLYYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQI
                     SSLASNMPDFIKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSL
                     GSIVGTIASATVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTL
                     ANYISGQAIECLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLV
                     TVFNDPVKALLCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLG
                     IFLGVPFYAICKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            15428..15862
                     /locus_tag="IXR40_000757"
     CDS             15428..15862
                     /locus_tag="IXR40_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4360627.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            complement(15940..16473)
                     /locus_tag="IXR40_000758"
     CDS             complement(15940..16473)
                     /locus_tag="IXR40_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HAQ4360628.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(16567..17745)
                     /gene="mutY"
                     /locus_tag="IXR40_000759"
     CDS             complement(16567..17745)
                     /gene="mutY"
                     /locus_tag="IXR40_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HAQ4360629.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(17738..18535)
                     /gene="recX"
                     /locus_tag="IXR40_000760"
     CDS             complement(17738..18535)
                     /gene="recX"
                     /locus_tag="IXR40_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HAQ4360630.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            18642..20024
                     /gene="rlmD"
                     /locus_tag="IXR40_000761"
     CDS             18642..20024
                     /gene="rlmD"
                     /locus_tag="IXR40_000761"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HAQ4360631.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(20198..20776)
                     /locus_tag="IXR40_000762"
     CDS             complement(20198..20776)
                     /locus_tag="IXR40_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitin-binding protein"
                     /protein_id="HAQ4360632.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            21098..21568
                     /locus_tag="IXR40_000763"
     CDS             21098..21568
                     /locus_tag="IXR40_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HAQ4360633.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
     gene            complement(21676..22902)
                     /locus_tag="IXR40_000764"
     CDS             complement(21676..22902)
                     /locus_tag="IXR40_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytR family transcriptional regulator"
                     /protein_id="HAQ4360634.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
     gene            complement(23656..23856)
                     /locus_tag="IXR40_000765"
     CDS             complement(23656..23856)
                     /locus_tag="IXR40_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAQ4360635.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
     gene            complement(23990..24598)
                     /locus_tag="IXR40_000766"
     CDS             complement(23990..24598)
                     /locus_tag="IXR40_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HAQ4360636.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNSAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            complement(24683..25153)
                     /locus_tag="IXR40_000767"
     CDS             complement(24683..25153)
                     /locus_tag="IXR40_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HAQ4360637.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            complement(25201..26115)
                     /locus_tag="IXR40_000768"
     CDS             complement(25201..26115)
                     /locus_tag="IXR40_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HAQ4360638.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKDVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            26261..27064
                     /locus_tag="IXR40_000769"
     CDS             26261..27064
                     /locus_tag="IXR40_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HAQ4360639.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            27242..28189
                     /locus_tag="IXR40_000770"
     CDS             27242..28189
                     /locus_tag="IXR40_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HAQ4360640.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
     gene            complement(28257..28550)
                     /locus_tag="IXR40_000771"
     CDS             complement(28257..28550)
                     /locus_tag="IXR40_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis protein"
                     /protein_id="HAQ4360641.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEIDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
     gene            complement(28578..29243)
                     /locus_tag="IXR40_000772"
     CDS             complement(28578..29243)
                     /locus_tag="IXR40_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HAQ4360642.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            complement(29383..30015)
                     /locus_tag="IXR40_000773"
     CDS             complement(29383..30015)
                     /locus_tag="IXR40_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4360643.1"
                     /translation="MIKVLLVDDHEMVRLGVSFYLSIQEDIEVIGEAENGRQGYEKAM
                     TLRPDVILMDLVMEEMDGIESTKAILKDWPEAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNEPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            complement(30022..31089)
                     /locus_tag="IXR40_000774"
     CDS             complement(30022..31089)
                     /locus_tag="IXR40_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAQ4360644.1"
                     /translation="MMGKISRAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLLAISLGVGLIVFLLLSLIQKTKYGKIEEKLRALSSGNYESKLLLLP
                     IPSASDDLYIKDIDKEITKIKEKMIEVSSELQIVTSRPQYVDGQTKEEILELERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWDVEDVKLSSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVEIKVPLMKEA"
     gene            complement(31086..31817)
                     /locus_tag="IXR40_000775"
     CDS             complement(31086..31817)
                     /locus_tag="IXR40_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HAQ4360645.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKHPRTKFQNFQLILGSLVIFFSLVNSPALWMMAVFAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMIQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAVISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKIYSS
                     DYDENPRRLKIITNTLIGDVEVIRI"
     gene            complement(31986..32465)
                     /gene="greA"
                     /locus_tag="IXR40_000776"
     CDS             complement(31986..32465)
                     /gene="greA"
                     /locus_tag="IXR40_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HAQ4360646.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGE
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            complement(32601..33776)
                     /gene="mltG"
                     /locus_tag="IXR40_000777"
     CDS             complement(32601..33776)
                     /gene="mltG"
                     /locus_tag="IXR40_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HAQ4360647.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELHQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVEKYVNNS"
     gene            33980..35149
                     /locus_tag="IXR40_000778"
     CDS             33980..35149
                     /locus_tag="IXR40_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HAQ4360648.1"
                     /translation="MKKGKHAKKRKYSFLMIVVVLFSLSAFSTGTILGWQFYNNEHSQ
                     IVAHAQSAQKKLILTTNEQQLVEKIDQLLRKNDYIGSIYVKKNNRIIMEKGYGYANKL
                     TQQPNDPSLYYQIGSVQKALTTLLILKQVERGHLSLDTKLAQFYPQIAGSQQITIRDL
                     LYMRSGLHRTASPTIPMTDEEVVQFAIQHLKFTDYQTSHYDSLNFTILTGILIKLTNQ
                     PYEKLLTDDIIEPLGLQHTKFYDQVKNSSNHALSYQMSKEDDYFKPLTESETEIHNEL
                     GTGNISMSVYDLNTLFTQVLSGKLVSKDLLFSLWRENANGHPYSGGVYSGDNYILSQG
                     NIDSFDTSAIFSKDSQDAIIMESNIKADKTIKLPTADLRNQIYDLMEGTTKLANS"
     gene            complement(35416..37038)
                     /locus_tag="IXR40_000779"
     CDS             complement(35416..37038)
                     /locus_tag="IXR40_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360649.1"
                     /translation="MNLKKIFSVKIFIVYAFVSLLYLFPAFKNMEIFGFYDTAFHINR
                     ALSLESIFSSPINFETFRSYGMQVNNFYPWLTLYPLFLLIKFTNLAIGYNLFLYIVTL
                     ITLFICHYVMYEITKKHVTSSFFAIIYTTSSFRSVEIFLRGAMGELLAMSILPLILLG
                     FIKLYDSKKESWVMLAISMTLLIYTHVLSVAMTMVMIIIALIIQFYRKKKIEIFLIIK
                     LIKAAIVTLLLSLAFIGPMIEQTLYQDLNRPYVDILQKRAIYLGKEFLIGSIDSELLS
                     FGIGLTLLICLIILTFNFKKLGILSKITYIMGIISILLCTKIFPWFALQNTPLNIIQA
                     PWRFMIFSTLFISFSVSLFISPQLEKFSYTRRRNFILLLILAISILNYSSVVNMVKEM
                     NFQGTYSNEQMENKLEEFENFDYVPIGYKKDQLLLKNHQVTEDGQVIYSSFSPNKDEI
                     TFTFKSSKGKTIVLPVFRYKGLTVTVNSKNATVLKQGGPFVTVKSESGINKVTIRYSY
                     TFFSKISLFISIITLIVLLFYCIKLKIRTSHE"
BASE COUNT        11350 a         7372 c         6079 g        12368 t
ORIGIN      
        1 cacatatttt gattatcaaa gtattttctg tgaacagaac tatagaattc cctaaaactt
       61 gtccattatt tcaaaatttg ttatagtctt tttattcaaa gcgtaaaagg agatcctatg
      121 ttaaaagaaa aaatgaaaac tctccccatg ctgccgggtg tctatcttat gaaagaccga
      181 gatggtaagg tcatctatgt tggtaaagca aaacggctca aaaatagagt aagcagctat
      241 tttcatcaga ataaacagca ttcaaaaaaa gtattacgta tgattcatca tataacagat
      301 tttgatttcg tcgtagtaga cacggaatta gatgctttat tgctcgagtg tcaattgatc
      361 caacattacc gtccttttta taaccgacaa atgaattatt tcagtaatta taattatgta
      421 catattacca ataagggatt tgtattaaca gatactccta cggctcgaac atacgggcct
      481 tttcgtctct ataaaaaaat gccgtctatt ttgcgtataa tggaagaaac ttatcaaatg
      541 ccttggttgt ctgaaattag tttgttagct ttgcgagtcc agcttcctga cctacaggaa
      601 atgacttttg aacagaaaaa aaaggaactc caagggctgt ttcaaggccg aaataaaaag
      661 ctactgactt acttgaaaaa aagacaacaa catttcatct atcagttgaa tttcgaaaaa
      721 gccggtatgc ttcaaaaaga tatcgaatta gttacttatt ttattagacg gatccaggaa
      781 caaaagcagt ttttaagaac accatcgctc accttcagca tgccattagc agcagatgag
      841 agtcagaaaa agcactacct cgtttgttat ggtcaacttg cagaaacaat gattacctct
      901 ggtgacgttt ctcctgactt ctattatgaa aagaaagaag ctcatttatc tttgaaacgt
      961 caattgtcaa aagaagaaat cgatcctgta caaatcttga tcagttaccg caaaaaatta
     1021 gaaaaagaac agtttgaaat tgaactgtta aacaaaaaag aagctgaaaa gcaactaaat
     1081 tagttgcttc tcggcttctt ttaggcatct tcaacttcaa atgtcaatta tcctaaaatt
     1141 tattggatta agtcatagat ttccatcgct acgatatcga tattatcaaa ttcgtattgc
     1201 tgatgagtat ctgtttcagt taattcaaat gtatcggtcg ctttatcata agttactgta
     1261 cacttctcta cgccttcttt ttcaaaacgg cgaacttgca gttcattatc tgctgactcg
     1321 accatagcct ccagtcgttt tatgattgcg actaattgtg aatgtgtcat cggaggtcct
     1381 ccttttctta tttctgttat attgtatcaa aagcatagcc tacttgcatt gattttctct
     1441 aaaaaaactc gttttttatg attttttttc tggtattttt ccttcaggcc accaaagttt
     1501 gatcaaagct tgggttccgt cattctcaaa acctttatct gccaactctt catatagttt
     1561 caatgcttgg gtagttgctg gcaatacaag atccattttt tctgcttctt ctaatgcaat
     1621 ctttaaatct ttgataaaat gtttgacaaa aaaaccaggt gtataatctt cttttaaaat
     1681 acgaggagaa taattgctta aagaccagtt agctgcactt ccacctgaaa gcgtctcaat
     1741 cactttcttt aaatcaagtc cgtttttttg tgcatagaca agcatttccg tcattcctgt
     1801 catcgtacct gcaatcatga tctgattagc catttttgta tgctgacctt tcccagcaga
     1861 accatgcaat gtaaatgtcg taccaaattc tttgaataaa ggcagtactt gatcataaac
     1921 ggcttcttct ccaccgacca tgatcgtcag tgtaccattc tttgctccta agtcaccacc
     1981 ggataccggt gcatctaacg catctgcgcc tttttctttt gctgtttttg caattttttc
     2041 tgccaggctt ggtgtacttg tagtcaaatc aactaaaata tgtcctgaga tatctgcaga
     2101 aaaaatcccc gactgtccat agtagatttc ttctacatct ttggggtaac ctaccattgt
     2161 aaagagaata ttactttgtt ctgctaccgc ttttggtgta tctgcccaga tagctccttc
     2221 tgttactaaa ggatcagctt ttgcttttgt ccgattatag acagctactt cgtgtcctgc
     2281 ttctagtaga tggcgtgcga cagcacttcc catgacgcct gttccgataa aaccaagttt
     2341 cattttttcg acctcctaaa aatcaaaaat ccttgcttct atgctagtat acgctagaaa
     2401 caaggatttt ttcataaaaa atgtttgaat tttatctttt aaatgaattt aattttattt
     2461 tgattcgttc aatcgagtct tcttcttctt ttcttcgcat ctcttcttca tgataaacaa
     2521 ccatgtcttg ataaaattcg atcatagctt cgccgaaatg tgtagatgaa atatcataaa
     2581 gtttagcttc taaaactttt ggatctttag gaacttcact ggaaatataa tcaataagtg
     2641 ctggtgcaaa gtcttcgtcg gtttcaaaag ttttccctaa tgaaggatga tcgaacaatc
     2701 ggttcaaata agcatttcct tccacgacac aaggtgttcc ggctgccatc gcttctgtat
     2761 aagtaagccc ttgtgtttct gaagtagaag cactgacaaa ataatctgcc gctttataat
     2821 aaagtgctac atcattgttg tccacttctc ctgtgaactg cacaaattct tctaactgca
     2881 gttctgagat caattcctct aactcttcta cataaggtcc ttttcctacg ataactaatc
     2941 tggcgttagg ataagcggag atgacctgag gaaacccatt aatcaaggct tggatatttt
     3001 tctcataaga aatcctgctt aaagaaagaa tcatcaaatg gttttcctga agacctagtg
     3061 actcccttaa tttgctgata tcctgctgag tgatatcaga acgtttgaat ttttcaatgt
     3121 cgataccagt aggaatcacg cgaagcggtg ctattacacc atagctgcgt aatgtatcaa
     3181 taacacgttc acttggacaa actacacctg tcgtatgatt tgcaaataat ctagacaagt
     3241 attttacatg ggattgcctg atcacttttc ctttaccgat ataatgaagg tagtcttcat
     3301 acatcgtatg gtaagtatgg atcagaggta ttttcaactt cttagctacc atcttcccaa
     3361 gtatccctgc tccgaattct gtatgggtat gaataagatc tagttctagt tctttggcaa
     3421 ccaaataagc ataccacatg cctctaacaa caactcttcg atccttgaaa gaaataaatg
     3481 gtacacttgg cattcgaatc acatcttttt ccaacttatc cgcattagga tcggtcgttg
     3541 taaaaatata gacttcatgc ccatgtcttt ctaattcttg ttttaatgtt ttgatcgatg
     3601 tagcaactcc gctgacttgc ggaaagtagg tatcggtaaa aaagccgatt ttcatgtttt
     3661 tcgcctccaa actagtcctt gacctgattt acttttttta atttgctaga gactttttca
     3721 ttcagtacac tttcgtatac atttttaagt tcttcaccga ttttattgat acttcgctct
     3781 tttgctgttt gataaccggc ttgtgtcgta ctcggtagtt cttgattggt aatctgttgg
     3841 atcagtcgga taaattcttc gtttgtcttc cccatatagc agttcttgct atcttctaac
     3901 cagccattat acactggaat atctcgaaca agtacgtttt gtttgcttgc taaagcttct
     3961 aaaacaacga tcccttctgt ctcttcataa gaagggaaaa agaatagatc tgcacctgaa
     4021 tacgcacctt ctatgatctc tccacgaatg taaccaggaa acaggacatt ttcaggatga
     4081 tcttctttta caattttccg gatgttccga ggaatcgagt acatgggaac atgaccaaac
     4141 caaataaatg tgtattcggg catcttctta gcaatttcta cgaaatcaat gattccttta
     4201 cgttcgaaaa acaaaccgac acaaatgatt actttttgat ccggagacag tttgaaatat
     4261 tctctgaact tttgttcttt cattggatca gggtgatatt tctctaagtc gatcccattg
     4321 gaaatagctt gaatcggcac acggatacca tagctttcca acaactgttt tgaataaggt
     4381 gttggcgtga tcagatagtc cgctttttgg tacaatccta ccagatattt ttttacgata
     4441 ggagaaagct ggttcgatct gataaaggaa tttcggaaat cttcctctgt agaatgcgca
     4501 tgatagacaa ctttttttcc ttctcttctg gctttattga ccatattatg actattgatt
     4561 ccgtatgtat tgatgtgcag gatgtcataa tcttcttttt catctagtgt ataagagata
     4621 ccgacttccg tcagagcacg tttttgatga tcaagcgcac gcccgattcc agattttgca
     4681 agcatctttt cactttcaaa atataataat accttcacct tacgtccccc ttcacttata
     4741 tagtataaca tagcctacaa actgtcactc aaacttaagc cctatttttg tctattctta
     4801 ctgacaaaaa cgttttctta aaaaagaaca aaaaaactgg cgtagctctt ttacaagcca
     4861 caccagcttt tgatacgttg tttattttac atattcatga acaagttcaa cgacttcttc
     4921 catcatatcg cattctttca atgcacgatc agcaagttca gccattttcg ctgtgtccaa
     4981 gcgtttcatt aaactacgcg ttttaagaat agatgtcgca ctcattgaga actcatctag
     5041 acccatacct actagcaatg gaacagctgt ttgatctcca gccatttctc cacacatacc
     5101 tgcccatttt ccttcagcgt gtgctgcatc aattacattt ttgatcaaac gtaaaattga
     5161 tgggttatat ggttggtaca agtaagaaac gcgttcgttc atacggtctg ctgccattgt
     5221 gtattgaatc aaatcgttcg tacctacaga gaagaaatct acttcttttg caaacttgtc
     5281 tgctaagact gctgctgctg gaatctcgat catgatgccg acttggatcg tatcagatac
     5341 ttccttgcct tcacttatca atttttgttt ttcttcttca aagatcgctt ttgctgcgcg
     5401 gaattctttg agtgtagcta ccatagggaa catgatacgt aaattaccat gaacagatgc
     5461 acgaagcaat gcacgcattt gtgtacggaa catttcgtcg ccttgttcag ataaactgat
     5521 acgcaatgca cgatatccta agaatggatt catttcatga ggtaattgca gatatggtag
     5581 ttctttatct ccaccgatgt ccattgtacg aacaactaca ggttttcctt ccataccttc
     5641 taatacagct ttgtaagctt catattggtc atcttctgtt gggaagtctg gagaatccat
     5701 atacaggaat tcagtacggt acagaccaac tgcttctcca ccattattat ggacaccaac
     5761 tagatctttt ggtgttccga tgtttgcagc taattcaaaa tgcttgccgt cagctgtgac
     5821 agtttctgca ttttttaatt tttcccattc tgctttttgt gctgcgtaat ctgcacctgc
     5881 tttttcaaat tcagcttttt gttcatctgt aggatcgatg attacatcgc cttcgatccc
     5941 gttgacagcc aaaatatcgc cttctttgac tttagcagta atttcttttg tcccaacgat
     6001 tgctggaatt tctaaagaac gtgccatgat agcagaatgt gaagtacgtc caccaatgtc
     6061 tgttacaaac gcttttacaa aattgcgatc taattgtgct gtatcacttg gagtcaagtc
     6121 atgtgcaaca acgaccactt cttcgttgat cattgatgga tttggtaaag taacgcctaa
     6181 taagtgcgct aaaatacgtt tagcaacgtc acgaatatct gcagcacgct cttgcatata
     6241 agcattatct tccattgctt cgaacatacc gatatacata tccgttactt cttttagcgc
     6301 tgattcagca tttacgctgt tgtctttaat attttgcttg atttgaccta ccatttctgg
     6361 atctgaaaga accatcaaat gggcatcaaa tacttgcgct tctgcttcac ctaagctttg
     6421 cgctgctttt tcacgaattt gctgcaattc ttcagtagat ttagctaatg cagcatccaa
     6481 acgagcttct tcagccgcag tatcttctac tgttgcctta ctgaatgtta aatccggttg
     6541 aactagcagg taagcttttg caacggctac accgtcacta gcggcaatcc cttttagcat
     6601 ttcaaccatt attcagataa gccttctttc ttcattgttt caacgattgc tgccattgca
     6661 tcagcttcgt cagcaccttc tgcagtaata gtaacatcag aaccttgacc tacacctaaa
     6721 gacataacgc ccatgattga tttcaagttt actgatttac ctttatactc taagtttaca
     6781 tcagagttaa atttgcttgc tgtttgtact aatagtgtag ctggacgagc gtggatccca
     6841 gtttctgcta ctacgtgaaa ttctttcttt tccatattaa tcggtctcct ttaagtgagt
     6901 gttgttttta tgtgagggtt ttctttttta gtaattcaga gaatcctaac aaatgccacc
     6961 ctttcatctg taaagattaa catttttttt cgttagatac aacagttttc attcaatttc
     7021 agataaaagt attcaaatta ttccggattc tttttcatcc ttttcttcac attttataac
     7081 aaacgtgttt atttcctttt tcttgtcgct ttctcttctc ctgacgttta tcattctttc
     7141 ctttgaccct ctttgttttc atatgaaacg aattacttgc ttcccttttt atttttagta
     7201 taataagagt caaaggtcag gaatggtcaa tagagatttc accttttcta cctcataaat
     7261 ctcttaaaaa actaggggtt attcttttac ctcatgaaaa acgagatgta aaatatggat
     7321 gtacccattt ttgtgaaagg acgtgaatga ttcatgcttt gtcaaaactg cggcaagaat
     7381 gaggcaacga ttcacttgta tgccactgtc aatggtcagc ggacacaact cgattactgt
     7441 cagagctgtt atcaaaaaat caaaaatcaa caaaatggag gtctgactaa tatggcccaa
     7501 aatgatccat ttggatttgg cagtttggac gatcttttcc gttccatgtc tcgccaaatg
     7561 caacagcaag gaaattatga gcaaacacca ccaacacaat ttggcggaaa caacaacttc
     7621 aatggtggtc agccacctca aggcaataca gaaggtttat tgggagaata cggaatcaat
     7681 atcacagaac aagcacgaca aggtgatatc gatcctgtga tcggacgcga tgacgaaatc
     7741 aaacgagtca ttgaaatttt aaatcgccga accaagaaca atcctgtctt gattggagaa
     7801 ccaggtgttg gtaaaacagc agttgttgaa ggtttagcac aaaaaatcgt agatggtgat
     7861 gtaccgcaaa aattaatgga caaagaagtc attcgtttag atgtcgtatc tttagtccaa
     7921 ggtactggta tacgaggaca atttgaagaa cgtatgcaaa aattgattga agagatccgt
     7981 caagcagaaa atgtgatcct attcatagat gaagttcacg aaatcgtcgg tgctggttct
     8041 gctggtgatg gaaatatgga tgctggtaat attttaaaac cagctttagc tcgaggagaa
     8101 ttgcaaatgg ttggtgctac taccttaaat gagtaccgca tcatcgaaaa agacgctgct
     8161 ttagaacgtc gtatgcaacc tgtacgggta gatgaaccaa ctgtcgaaga aacgatcagt
     8221 attttgaaag gtttgcaaaa acgttatgaa gactatcatc atgtaaaata tactgatgag
     8281 gccatcgaag cagccgcaac tttatccaat cgttacgtcc aagatcgctt cttgccggat
     8341 aaagccatcg atttgctaga tgaaacaggt tctaagaaaa acttgacgat ccaaatcgtt
     8401 gatcctaaaa caatcgagaa aaaactgcaa gaagcagaag aacaaaaagt tttagcttct
     8461 cgagaagaag atttcgaaaa agcagcttat tatcgcgatc agatcaataa acttcaaaaa
     8521 atgaaagaac gtcagctcac tgaagaggaa acacctgtga ttaccgaaaa agatatggaa
     8581 aaaatcgttg aacaacggac aggtattcca gtgggtgaat taaaagaaaa agaacagaca
     8641 caactgaaaa acttagcaga tgacttgaaa gctcatgtca tcggacaaga taacgctgta
     8701 gatcgagtag cgaaagcgat tcgccgaaac cgtgttggat taaacaaaca gaatcgtcca
     8761 atcggctcct tcttatttgt tggaccaact ggtgtaggta aaacagagct tgcgaaacaa
     8821 cttgcctacg aactattcgg ttcacaagat tcaatgattc gtttcgatat gtctgaatat
     8881 atggaaaaac atagtgtctc taaattgatt ggttctcctc caggttatgt cggatacgaa
     8941 gaagctggtc aattaacaga aaaagtacgg agaaatcctt acagtcttgt cttgttagat
     9001 gaagtagaaa aagctcatcc agatgttttg catatgttct tgcaaatctt agatgatggt
     9061 cgattgacag atgcacaagg aagaacggtc agctttaaag atacgatcat cattatgaca
     9121 agtaatgccg gaactggtaa agtagaagca aacgttggtt ttggtgcggc acgcgaaggt
     9181 gttactcgtt ctgtattgaa ccaattaaac aactacttta caccagaatt tctgaaccgt
     9241 tttgacggga tcatcgaatt cagtgcatta tcaaaagaaa acttgatgac aatcgtcaca
     9301 ctaatgctag acgatgtcaa ccaaatgctg gcagcacagc aacttcacat cgaagttcct
     9361 acgaatgtca aagaaaaatt agttgactta ggctatgatc catctatggg tgctcgtcct
     9421 cttcgacgca cgatccaaga acaaatcgaa gatggtatcg ctgaatttta tcttgatcac
     9481 ccttctatcc atgagttgaa agcaaaactg gataaagatg gaaaaatcat cgttacttct
     9541 aaaccagaac gtttggctaa agaatcagcc gaagaaacgg ctgaataaat ccagttttat
     9601 agcgtgagac ggtatttctt tgagaaatgc cgtctcattc ttttttcaga aaagtcaaaa
     9661 tactgttcat tttataaaaa agaaattata ataagagaaa caagcaatta aaaatacata
     9721 aaagaggtga gcgccatgaa attggtaaat gtaacaaaca gccattcccg tcttgtatta
     9781 aaccagcttg aaaacactga tgcccatcta gtcaaggtct acacagccgg aaataccact
     9841 attgtctaca ctgaagcccc tgaacataat gaaattctgc tgatcaatga caaacgtaaa
     9901 atccagccga aagaaatcga agatgctaaa aattatttct tagataaaat caaagacgcc
     9961 gtttaccacg aggatgaaat caaagtaatc gaattggcag gccttgttga aatctcgatt
    10021 ccaaaacatg aattaggcgc tacattagcc gtgtaaacaa attttgaaca taataattaa
    10081 agagcgtggg acaaaagtaa agaacacttt tgtctcacgc tctaaacacg tataaacggc
    10141 gaaagcagaa gcaactcctt cggaaataag ctgaaattca cgaaaattgc ttttcaaatt
    10201 tttgtgaatt ccagcttatt tcttggagtt aaacgcttct gtctcagcct ctttttcttt
    10261 ctagcttttt gatttttctc ttttcttttg tacttttctc ttttcatttt cagttctacg
    10321 cgtgtcttta tttttaactt tttcctcttt atggatgatt gatcgtactt tttgtgcaat
    10381 ttgctcgttt ttgtcccagt cttttacatc taataatcga cataatcgta acatctcttc
    10441 ttttttctgt ttttttcttt cacgtctttg ccattctgtt tccatgtgtc acactctcct
    10501 ttctttaatc atatgtacgc aaaataattt ttatattttt ttgattagac atttctatga
    10561 ttttaatata gtaaaaagag ccgtcacgga aaatccgtca cggctctaaa caaaatatga
    10621 gaggctgttt ttgtttggct attcttatta cttgatgcag ggcagcttgt gtcaagactt
    10681 ctttacatca aactttttaa ttttacattg ggatatttat ccgcaaacca gcgttctgca
    10741 aattggttct cgaataagaa caacggttgg tcgaaacggt cacgagccaa gatattgcga
    10801 cttgaactca tcttctcatc caaatcttct ggatcgatcc agcgagcgat tttgtgtccc
    10861 attggagaca tgattacttc ggcgttatac tcatttaaca tacgatattg gaatacttcg
    10921 aattgtagct gaccaacagc tccaatgata tattcttccg ttagatatgt tttataaagc
    10981 tgaatcgctc cttcttgaac taattgatag attcctttgt ggaaggattt ttgtttcatg
    11041 acattttttg cagtcacttt cataaacagc tctggagtaa atgaagggag ttcttcataa
    11101 gcaactttta gttttccttc gaacaatgta tccccaatct gataattgcc tgtatcatat
    11161 acaccgatga tatcgcctgc tactgctttt tcgacgtttt ctctcgaatc tgccataaat
    11221 tgtgtgacat tgcttaattt cagtttttta tttgtacgtt ccaaccagac atccattcct
    11281 cgttcgaatg ttccagaaca gattcggaca aaagcgattc ggtcacgatg ggctggattc
    11341 atatttgctt ggatcttgaa tacgaaacct gaaaattctt cctcataagg acttaccatc
    11401 tgatcatctt gtgttttgtg tccataagga gctggtgcca attcaacgaa agtctctaaa
    11461 aaagtctgta caccgaagtt agtcaatgca gaaccaaaaa atactggtgt ctgatcgcca
    11521 cgagcaattt tttcttgatt aaatgcatct ccagcctctt tgattagttc tacttcttct
    11581 aagacttgtt catataagga attttcagtt agaggatgat tttcgggaag cagtccatct
    11641 tcatccaatt ctactaatcg ttcatcctga taattttccg gacgataaaa ctctacacga
    11701 ttatggtaga tatcataaag accttctagc cctttaccca taccgattgg ccaattcatc
    11761 ggataagatt cgatatctaa tagctcttct aattcttcta acaattccaa tggttcacga
    11821 ccatcacgat ctagtttgtt gataaaagta aatatcggga tgccacgttt ttttacaact
    11881 tggaataatt tctttgtctg tgcttcgatc ccttttgcac tatcgattac catgaccgca
    11941 ctatccacgg ccatcaaagt acgataagta tcttcagaaa aatcttcatg tcctggtgta
    12001 tccaagatat ttactcgttt cccttgataa tcaaactgca taacagaact agtaacagaa
    12061 atcccacgtt gtttctcgat ttccatccag tctgatttgg caaaattacc tgtttttttg
    12121 ccttttacgg tcccggcttg acggatagcc ccaccaaaca atagtaattg ttctgtaatc
    12181 gttgttttcc cagcatccgg atgggaaatg atcgcaaaag ttctgcgatt gtccacttgt
    12241 tgctttaatt ttggattatt cataacctaa ctccatttct tccattcaat tatttatatt
    12301 ttctctaggc acagattgtc cgatctctta aagaaagaca atttcatata gggctgtgac
    12361 aaaagccgtg tagcagtctc tttttccgag taaacggcgt tctagagaca gcctatcagc
    12421 aataagccca cccaagccaa aaatacgaaa agctgttttt gcttggctgc tcttattact
    12481 taatgcagga tagctttttc acaacctttg tcaactacta caactgaatc agtatagcat
    12541 ggattcagcg aatgaaaaag ccaccaaacc ataagagtca aatatttttt tgtcagctga
    12601 ctaaaagaaa agacgtgttg cttgtttatt caagcaacac gtctttcata accaagtttc
    12661 caattatctt cttggctcgt catcttcgaa ttcttttctg aagtatcttc gttcttcttc
    12721 aggttccgct tctgtttctt ccggatcatg aaaaatgaca cggattttaa ggattcgaga
    12781 accttccatt tcttcagaaa ccagcgtaat attatcgaca tcaaacgata acttttcgcc
    12841 ttcatccgga atcatgccta atgctgtaat caaataacca gccatcgtat ctacatcact
    12901 catatgcaga tcactgtcaa aagcttcatt gaactcatca atcagcatac gtccttggat
    12961 gatatattcg tgttcatcga ttttttcata aagattctca acttcatctg attcatcatc
    13021 gatttctccg acgatttctt ctaaaaggtc ttctagtgtt gctaacccaa cgacgccgcc
    13081 atattcatct aataaaatag ccatctgatt ctgcgtcttt ttcatttcat ataacagatc
    13141 atcaataaag accgtttcag gaacgaataa aggctcctgc atgattttct tgatatctaa
    13201 attatcaaag ccgaatttat gggcagcttt tagtaaattc tttgtatgaa ggattccgac
    13261 tactttatct ttgtcttcgt tataaacagg gattcttgaa tagttttcgg ataaaacttc
    13321 attcacattt tcttccacag tgtcgttgat atcaatcata aatgcatccg ttcgtgggac
    13381 catgacttct cgggcaactt tcgtatcaag agaaaaaacc ccttggagca tttctaattc
    13441 ttcattattc aatacgcctt cgttttcaag catataacgc atttcatctc tggtcatttt
    13501 tgaatcttca tcatcaaaag tcatcggcgt gatacgcgcc aataaacttg tggaagcaga
    13561 aagcagccag acgaagggct tagctactac accaatcaag cgtatcagcc ctgaagtgaa
    13621 ctttgcgact tcttctgatt tatttaaagc aatacgttta gggtacaatt ctccaaaaac
    13681 aatcgataca taggtcaaaa tagccagcac aatgatattt gcaatatttt ttgccgctgt
    13741 gccgccacct aataccggag ctaaccgttc cgataaagta ttagctagtg aagcaccaga
    13801 caaaatgttg accaaagtga ttcctacttg gattgtcgat aggaaattat ttggattctg
    13861 caatattttt aaaagctttt gagatttcac atctccttca tcagcttttt gctcgattcg
    13921 attcttattg atcgaaacaa cagcaatttc ggaagctgct aaaaaagcat tgatcaatgt
    13981 caaaacgatc aataataaaa tctgcgctaa cagcgactga ctctcagggt cagcattcat
    14041 aatcgcattc tctccttata aaattaattt ttagtttacg atagaaaaaa acgtggcact
    14101 atagccacgt taaaatggta tcacaaagca attttctttg caataaaaac aagtgtacta
    14161 aaactaccta cgaggtcgta gcaattttct tcttgttttc attttgcttg tcttctttga
    14221 cgattttgat tatataggaa atgatcgtct tgcagattgc gtaaaaagga acacctaaga
    14281 agataccaag caatccggca atatttccag ctactagaag aacgataatg atcgttaatg
    14341 gatggatttt cagtgatttc ccaattacat taggataaat gatattccca tccaactgtt
    14401 ggacgattag cacaaccaca caacaaagta atgcttttac cggatcattg aagactgtta
    14461 ctagaaatgc aggtgctagt cctagataag gtcctaaata tggaattagg tttgtcaatc
    14521 ccgcaatgac cccaaataag aaagcataat ccacaccaat taccatatat cctaaaaatg
    14581 tgaaggtacc aacgaataaa cattcgattg cttgtccgct aatgtaatta gccaatgttt
    14641 tattcagttg ccccaataac tccacaattt ggtttcttct tttttctggg aaaaactgtt
    14701 ggatgtttgg cactagtttt tctccgtctt tcaacatata gaacaagatg aatggtgctg
    14761 taatgattac tacggttgcc gaagcgatcg ttccaacgat cgaacctaaa ctattggata
    14821 ctccactaag gaattgctga atgattgtcc cgtaagaaat gtctaattgc tcaaaatatt
    14881 tattgatatc tacttccttg aacaaaggca attcggctac ctcttttaac cagctttcta
    14941 cctgtttgat gaaatcaggc atattagatg ccaatgagga aatttgctgt actagacttg
    15001 ggatgacact aagtaaaatc caaataattg ctgcaactaa aaggagcagc acaattgcga
    15061 cagcccatat tcttttgatt tttgctttca tcaacagctt gacaatagga ttcaataaat
    15121 agtaaagaaa gcctgcaatc agtacaggtg caaataacgt ggaaaaaaat gtcccgatcg
    15181 gttcgaaaat aaagtttatt tctgatgaaa tcatgatcaa tgcagctatg atcaataatt
    15241 caagcgacca aaacattagt ttagactgtc taagtttttc aaacaataga tttcctcctt
    15301 tctttcttac tagtatatat tatattcgtt aaaaattctt ttattctttt tttatttttg
    15361 aaaacttgcc atacttttta tttgttttat tttccagtat actatacgaa aggaaggtgg
    15421 ctagaccatg aaagttgtac aaacaaaaga tacaatgagc aatatttact tagatgctgt
    15481 acggatcagg catcaagttt ttgtagtcga acagggtgtg cctttgtctc gagaaataga
    15541 caaagatgaa gcccattgta tccacttcgt cctgtactca gataaaaaag aaccgcaagg
    15601 aactgtacgt cttttgcctt tagaaaacgg aaaaatgaaa ttacagcgga tggcgattct
    15661 ttctgaatac agacaccaag ggttaggaaa aatattgatt gaagaagcag aaaactttgc
    15721 taagaatcaa ggctataata cgattttatt aggggcacag tccacagctg aaacttttta
    15781 cgaaaaacta ggatatacag cttacggcga tccttttgaa gatgctggca tgcctcatat
    15841 ttatatgaaa aagactttat aaaaatttat ttcgaaaaaa gcaaaaaaca gcaagctttt
    15901 gagaaaaatc tctcactggc ttactgttct tttttgtgtt tacttacgcg acaattgctt
    15961 gtaacggtta taccaaatat caatatagcc ttccgagaac gggccatctc cattattgat
    16021 ccagtcaacc agaatcttca cattttcttt taggatgaag tcaatatcgt tcgggtaatt
    16081 catcattttg ctgtgcatct catattcatc gacatccaat agtcgtttct cgccgtcagg
    16141 aaataccttg atatccaagt catagtcgat atatttcaag gcctcatcgt ccagcaaaaa
    16201 aggtgaagct agattacaat aataggaaac ccccttttct ctgatcattg ctattacatt
    16261 gaaccagtat tttttatgaa aataaacaat cgctggttcg cgcgttaccc atcggcgtcc
    16321 atcagattca gtgactaatg tgtgatcatt cacgccgatc atagagtgtt cgcttgtttt
    16381 taataccatg gtatctcgcc acgttcgatg caatttgccg tcgtgcttgt aactttggat
    16441 cgtcacaaac tctccttctt ttggaactcc catagcaacc cttccttaag cagcattttg
    16501 tgctttgtgt ttgggtgttc attacaccga catcataatt attatatcaa taaaaatgag
    16561 ctttgcctag aaaggattcc tattgtttcg atttttctct aactgatcta ccagtttcat
    16621 ttggacctta ggaaaaacga ccgaatcaaa tgcatcaggc ttcaaccact tcgaagtttt
    16681 gttctcggta aattcttgtt ctgctccctc ggttgcccgt ccgtaaaaaa ggagaacatg
    16741 ccatttcaga tgactaaaaa tatgagtaac ttctcctaaa tgtcgtgtct gccaaacaaa
    16801 gagttcctgc ttttcaaatg ggagattttg ctcttcttct gctactaggt catcaaacag
    16861 atcgatttct ggctttgttt cccattcttt tttcaatcgc tcatactcct cttgtgtcac
    16921 ttccatcatt ggaaatgtcc acatattcgc cagcaatttt tggctatctc tttcttcaaa
    16981 ataatacgct ccagaatgat tttgaagagc tgcactgata taataaacgt cttttggctt
    17041 tgcttttttt gtttttacag gaaaactcgt ttggattcct cgtttgttag ctaaacaaaa
    17101 ggcttggatc ggacaagtct cacactttgg agaagttggt gtacagatag ctgaacctag
    17161 atccatcatt gcttggttga attcacctgg atgcttttca tcaatgattt tccgcatcgc
    17221 ttcatcaaag attttcctgc tagaagcttt tgcgatgtct gcttcaatgc aaaacaatct
    17281 gctgactact cgcatcacgt tgccgtcaac tgcaggttct ggaagtccaa atgcgatact
    17341 tgcaatcgcg cctgtcgtat atggtcctat tcccttcaat gagctaattt cttcaggcgt
    17401 ttgcggcatt tccccatcaa attctgacat gatctgttta gcagcagctt ggatgttccg
    17461 ggctcttgag taataaccaa ggccctccca tgcttttaaa agcttttctt ctggagcatt
    17521 tgctagctct tcaattgtag gaaaccattc catgaaacga taaaaataat cgatcactgt
    17581 gtctactctg gtttgctgaa gcatgatctc agagatccag atacgataag gatcacgatt
    17641 atagcgccaa ggcaggtttc ttttttcttg ttcataccat tgaatgaact gatcttgaaa
    17701 ttcttttgtt tctttatctg tccatttttc ccattcttta ttcactttcc tcttcctttt
    17761 ccgtaatgaa tcgctggatc atatccaaat caaatccttt ttgatataag ctttgcttta
    17821 cttttagatt tcttttttta ggttcaaacc ttaaatttct tcgccatagt ttatctcctt
    17881 gtttgactaa ataatcatat tctatttctt gatctgcttc ttgcggaaga tcagctatcg
    17941 cttgttggat cacttcttga gaaaagcctt tcgtcatcaa tgtttgttgg atttttctca
    18001 ataattcttt ttggcttttt ccgtgatttt ttccaaacgc tttttcggct gtctgatgtg
    18061 cattttgaac ttggtcttca aatgtatatt ggctgagcgc ttgttcaatg atttcaggtt
    18121 tcaaaccttt ttgctgcatc tgctgcgcta atttctttgg tcctttgtca cttaagcgca
    18181 tattcgtgcg cacataactt tccccataga ccaaatcatc gacaaggtcc aattctttta
    18241 agcgggctac gattttattt cgatcttctt gaaggatttc cttttctttt aagtatgttc
    18301 ggatttcttt ttccgatcgc aactgataac ttaagtaatt cattgctagg tgaaaaccga
    18361 aatcagctcc gctactcttc ttgatctctt ggatagtttc ttcgtctaat tcccgtcctt
    18421 ttaataatcg atagcgtact aatacatctt cagatacttg taaagcttct ccttcagata
    18481 aatctacgcg atagaaaggg cctttgcctt tactgattct cgtaacggtt aacataaaca
    18541 tcctcctcga acatatattc tctatcatac cacagaaaat ccccgtaatc aggtattata
    18601 tgttagaata aaccacagaa aaaagaaaaa gggagatact tatggcagaa acaattgtca
    18661 aaactggaca aacggttcct ttgaaaatca agcgtttagg cataaatggt gaaggaatcg
    18721 gttatttcaa acggttgatc atatttgttc catatgcact accaaaagaa gaagtactag
    18781 tgaaaatcac gaaagcaact cctcgctatg cagaaggaga attaataaaa gtcaaaaaaa
    18841 caagcaaaga tcgcgtagtg gcaccatgtc ctgtttacta tgaatgcggt ggctgtcaat
    18901 tacaacactt agcttatcaa gctcaattgg attttaaaaa ggatctgctt ttgcaagcat
    18961 tggaaaaatt caaaccagca ggctttcgat cttatcaact tttgccgacg atcgggatgg
    19021 atgagccttg gcattataga aacaaagcac aatttcagtt acgaaaaaat aagcagactc
    19081 aaaaaattga agctggttta tacgaagcaa actctcatca gttagtccct ataacagact
    19141 gcttggttca agaacctcga acacaaaaag taatgaatac tgttgttcaa ctattgaata
    19201 aatttgatgc acccatctat gatgaacgga caaacagtgg aatcttccgc acaatcatgg
    19261 ttagaatcgg tgttaaaact ggggagttac aagttgtttt tattactcgc agtaaaaaat
    19321 tcccgcaaaa aaacgcaatg atccgtgaga tcaatgaacg actgcccgaa gttgtttcaa
    19381 tcatgcaaaa tgtccaggca caaaaaacgt ctctcgtgat gggggatgaa acgatccact
    19441 tatggggaaa agaagccatt gaagaacaaa tcaatgaagt gactttcgat ctttctcctc
    19501 gtgccttctt tcaactcaat cctcagcaga ccgaattgct ttatggcgaa ggaatcaaag
    19561 cattagatgt ccagcctaat gaaacgatcg tggatgctta ttgcggagtt gggacgatcg
    19621 gcttaagtgt agcaaaacaa gccaaagaag tacggggaat ggataccgtt cctcaagcaa
    19681 tcgctgatgc aaaaaaaaat gcggaaagat taggatatca caacactcga tatgaagtcg
    19741 ggacagcaga gcaagttctg cctaaatggt tgaatgaagg ttttcagcct gatggtatca
    19801 tcgtagatcc accacgtacg ggtttggata acgcattgat ccaatcatta ttgaaatacc
    19861 ctccaaaaaa acttgtttat atctcctgta atgtttctac acttgccaga gatctggtta
    19921 atttaagtaa aaagttcaag attgaatatt tacagtccgt cgacatgttt cctcagactg
    19981 cacgttgtga agttgtcgtg aagatgacga gactcgctga ctaaatgaaa gaggttgtga
    20041 aaaagtctgc cctgtatcaa gtaataagaa cagccaaaca aaaatagctc ttcatgtttt
    20101 atgaatactg tacttgtgac cgaagagtta acaggaggac actatttatt taaaaaaagg
    20161 gttgtgacat agtttttgtc acagcccttt ttgattatta ttggatattc acgtctatca
    20221 cttgataaaa tgcatttgtc gtatcgctga tattccatac tgctaaaatc acattatatc
    20281 cttttcgatc ctgcggaagt gtgatcgttt ggttgactgt ttttggtgga acagttgctt
    20341 tgtcgtctat ttttgtgatc aattcaaaat cactaaattt caaaggttga ttaggattcc
    20401 aagttggttt ggtaatgtag taatcccaag tacttgtccg atgttgtgct gttaaattcc
    20461 aagtaatatt taatgttcct ggattaacca tgtttttatg ccatctgtta gatgtctgtt
    20521 catctaaagg ctcaaagccg ctgactcctg cactagcaat ttttccatca atgaatgtat
    20581 ttttggtagc ttcgatactt tgcggttccc attgtgctct tccgacattt tgatttaagt
    20641 ttcctgctgc tgatgttcct aggtatgcac ggcttcctgg agaagtaata taaccatgcg
    20701 caaaacctgg aatgctaaaa ccgaacaacc ctaaactaac taacccaata aacaataacg
    20761 tactaatctt tttcatgtag aaacctcctt catttgataa ccacattgta aacgctttat
    20821 tgtattaaca caaacattat gcttttataa ttttatgttg aagtaaaaaa ggtgaaaaaa
    20881 gtaagatgca gattataaca gaagtagacg agaaaagtac aaatagaaaa catgagaatc
    20941 aaatcatatg atctttttca aaaacatcat tcatataaac aaatgttcaa ctttttaata
    21001 acaacaatta tcaatttttt tcttacttca caaactaaat acaggtcttg ctgtgagcct
    21061 tcatggtaaa ctaatattat agaaaggagt tagtaaaatg aagatgataa aagatattcg
    21121 tttttgggtt tgtgttatag gaattgtcat attaggcttt ttatcagggt tgcttagcgg
    21181 aaatcccgga aaatattact attctttgca acttccacca tttgcaccac ctagctggat
    21241 atttgggccg atgtggacct tactgtatat attgatgggt atttctcttt atttgttact
    21301 taatcacaac aacaaaaaac agcgaaacaa tcttgtcggt ctttttgtga ttcagttcat
    21361 ttttaatttt atatggtctg ctctattttt taatttaaga aatattttca ttgcagcaat
    21421 cgatattaca cttttagtta ttttcttgtc agtgcttatg tatcagttgt ggctgcatca
    21481 tcgcctggca atgtggctca tgattcctta ttatttatgg gtactattcg caactctatt
    21541 gaattattca atttattttt taaactaagc gctaaaaaga gacgtcctgt aatttaacac
    21601 atagaaaaag tgccacctaa gttagatttt ttgtctaatt taggtggcac tctttattaa
    21661 ccaaactatt tttttctagt acccacttgt tgttccatac tcattattct ggtcataacc
    21721 ataaccattt tgttcctgtc cagcgtaagg atcataactt tgagtatctt gacttggtgt
    21781 atagtactga cttgtatctt ctgtttgctg ataataggta ttcggatctt ggtactgatc
    21841 atatgtgttt tctgaatagg aagaataatc ggtgtaccct tcactattcg atccatcacc
    21901 gtttgtcgaa tcgccatctt ccgaatcatc aaagaacatc attgaagcat tctcattttt
    21961 caaattaggt aatgtatcgc ttgtttttat atttaattgt ttcttcagtt cattttggat
    22021 cgaaagaaga tcattttttc ctaaaatttg atagtagata tcattgatca tttgtccttc
    22081 gccttgcaac tggtcttgtt tgattgtttc aaacgccggg gtgtagttcg tcgctacatc
    22141 aagcatgtca tcccaatcta agtccgtcgt cacattgttc tcaactgctt ttaaaatttt
    22201 tctataattg cttacgccat ctaaacttaa aactttattg acgattttcg tcactacttc
    22261 ccgctgacga cgttgtcgac cgatatcgcc ttctggatct tcgtgtcgca ttcgagaata
    22321 ggctaaacct ttttctccat tcaatgtttg ttcacctact ggtacatgga caccatccaa
    22381 agtaaagtca attttattat tcactttgat gccaccgacc gcattgatca aatcttccat
    22441 gccatccaaa ttgatcgtta cataatgatc aataggaata tcgagcagtt gctcaattga
    22501 atccatggcc atttcgacac caccaaatgc gtaggcatga tttaatttat ctaccgttcc
    22561 ataacctacg atattcgtat aaatatctcg gtccaaactg atgatcgttg attttttttg
    22621 tttcggatta actgttacta ccatcatcgt atcagaacgt ccttgttccg ttcttcctaa
    22681 tccaccggta tctaaaccta atagcaaaac cgaaaaaggt tctttgtcat caatgcttac
    22741 tctctcagaa cgtttggagg atattcgatt agagttttta gaaattttgt ttactgtttg
    22801 gctcgcttct cccataaatc tgattccgta tgctgataat ccggcaatca gcaaaacgaa
    22861 tacccctaac aaggttaata gaactttttg ccatcgcttc ataatacacc tctgtttcac
    22921 attttctaaa atattgtctc atataactgt tcaatcagca aattcacttt ttaatcataa
    22981 gaaaacttta aaaaacattt ttgtgtaacg attattattt tttaaaattt ctcaaaattc
    23041 ttaactatca taccataccg tgaaaaagat cgaaagaccg aatacacgca gttcgcaatc
    23101 gttttatctt tttttatgta ttttttccag aaaaagcgaa caacaaggta ttttccaaat
    23161 aatcgtgcag taaaatgatc gcacatacct ttcccatctt tttaacagtc tttgcctacc
    23221 gttcagatta tcattcgatt tcacgacaat ttcttcctat gactggtcct tttgttaaac
    23281 ccatcttcta ttcgttttat ttccagctca ctgcatggct cttaaaatga ctcgaactag
    23341 tgattgcatt accatcatct tttaatggat agatatgctc ctcttcaaag taaaacgatt
    23401 ttcttttaaa gtaatagaat tgacatggta atgagtatgt atactagtgg tttcacaaat
    23461 ggtcttttat tcaacatcca aaaactgaaa tttctttaaa atccattact aacgaagaaa
    23521 atgttccttg cttgataatt agttaggaca tgtcaagtga acaaatgcat ttacttagcc
    23581 aaaaaatcta aaaacttcat aaatagacaa aaagacacga ctctctaaga agtcgtgtct
    23641 ttattcaaca aattattata atttagtcac ttcagcagct tgaggtccgc gtgcaccttc
    23701 aacaatcgtg aattctactt cttgaccttc ttctaggctc ttgaagccgt ctccttgaat
    23761 tgctgagaaa tgaacaaata cgtcatctcc gccgtctact gtaataaacc caaatccttt
    23821 ttcattgttg aaccatttaa ccgttccgtg ttccataaat gtatatcctc caaaaaagtt
    23881 cttgcaagta accttgcaag aacattatac ccaatttaga aaacgctagc aagctttcgc
    23941 tcttttattt tccaaattat ttttaagact gatatgacgg aggaaatggt tattttgctg
    24001 cttcgaaacg tttgtttact tcatcccaat taataacatt ccagaatgct gcaatataat
    24061 ctggtcggac atttttatat ttcaaataat aagcatgttc ccaaacgtcc aaacctagaa
    24121 ttggtgtctt tccttccatc aatggagaat cttgatttgc agtagaggta atagctaatt
    24181 ttccattttc cattacaagc caagcccatc cagaaccaaa tcgtccagcg gctgcttttt
    24241 tgaattcttc tttaaaagaa gaaaaatcac caaaagcttc attaatcgct tcttttattt
    24301 ctcctgtagg ttcgccacca gcatttggtg ccatgatttc ccagaaaaat gaatggttag
    24361 catgtccgcc accattgtta cgtacagctg tcttgatatc tgttggaata gcgtccatat
    24421 cagataataa ttcttctatt gttttttcgc ctaattctgg gtatttctca attgctgaat
    24481 ttaaattcgt cacataagta ttgtgatgct tatcatgatg cagatgcatc gtttcttcgt
    24541 caatataagg ttccaatgcg tcatatgcat aaggtagatc tggtaatgtg taagtcataa
    24601 aaaaattcct cctcaatgtt ttcttaataa tgtctacatt acaaagagta acaaagagaa
    24661 ggaaattctt caattgttat gcctagtcgt ctttttcact ttgacctact tcttcttcaa
    24721 aaacctcagt ttctttaaaa ataaacaact tgctgaaaat atagttcgca aggataacaa
    24781 taatttgagt gatgattttc gccacatact cattgctgtt cataacattg atcaacaata
    24841 ccattgcccc catgtccaat ccgtaagaaa ggatacggta gaagaagaac ttaccgcatt
    24901 caataagtgc atgtgtaaaa ttcggtgatt ttgaatggaa tacccaaagt ttgttcgtta
    24961 caaaagcaaa caatacagaa caaaaccacg aaatagaatt ggataaggcc atacttaaat
    25021 caaaatattg gcgtgcgaga gcaaaactaa caaaatttac aatcgtagcc aaaccaccaa
    25081 aaaagagata gactagtatc tcccaatatc cttttgcttc taaatatcct tttaactgtc
    25141 gatactgctt catgagccaa cctaccttat taaaaattct tatttatcat actctatatt
    25201 tcaataactt tcatctttat ttaaaaaaat taattttttt tgatcctttg cctttgtctc
    25261 tgcttggatc gtcacatgtg taataccata ttttaatttt aataaagaaa ttatacgagg
    25321 atatatcttt tcaatctcgc ttagtagctg atcttcaaaa tcaatatgtc cgtcgaaaat
    25381 aattatcttt tcgctatact gccaaatatg gacatgatga acatccttta ccccatcgat
    25441 tgcttcaatt tcttgttcca ttttttcata gtcgatagca ggtgcacttt gtatcaaaat
    25501 agcggcagct tttttgatca ccattatcgc ttctatcaat atatatatcg aaatgatcag
    25561 tgtaataact ggatcgatcc agtagatatc gaaaaaacgg atcaaaattg ctccgataat
    25621 cacacttacc gaagacagtg tatcacttaa caaatgcaaa taactagatt ttatattcaa
    25681 actttcatct gcttcttgtc gtaataataa tactgagaac aaattcgcga gcaatccaat
    25741 aactgctact gttagcatca aatgactatt tatcttttct ggtgaagtga accgcttgaa
    25801 tgcttcaacg gttaaaaaca aggataatat gatcaatatg aatgagttga tgaaagcact
    25861 caatatttct aaacgctggt agccatacgt acgtttttta tttgcttctt ttcgggccat
    25921 tttttgtgcc ccgtaagaaa aaataattgc caatgtatca ctaaggttat ggaaagcatc
    25981 tgaaacaaga gacaaactcc ctgacataat ccctccaata aattctgata aagtgatcac
    26041 cgcattcaaa accactactc caaatagttt ttttgatgat ctctgtggct gtgtaggcac
    26101 tattccttcc tccattttat ttatattgga tagtctttag acaagaataa catttttttg
    26161 atatttcacc aatcattcag ctgtttcctt aaagcacttg tatttcactt gatacttcgc
    26221 tagaattgca agtgatgaca ctactagatg aggagtactt atgacaacaa aacaattaat
    26281 tatcagttcc tttatacgat tcaaagacct aaaggaggcg agaaatgtcc cattttggaa
    26341 agccattgtc taccttttag ttttgagtat aattatggct ttgccaatct cttttcaagt
    26401 ttttcaagtc ttaaacaaca ttcaattgga tgggcaaaag attgctactc gcattcctga
    26461 ttttacaatc caaaacgggc agcttcaaac cgaagaaaaa gaaggattca tttaccaaac
    26521 aaactccatt atcttcacat ttgatccaga gggaaaacga acagaacagg acatctctac
    26581 tgatttgatg gggaattttg ttagtgtcgg gatgttaaaa aacaaactta tcatagctct
    26641 tcctaataca ggcacgactt ctgctttgtt gaacaataac caattagaac ttccctacac
    26701 caatgaatct ttaaaaaact taacaggtaa gcagctccgt tcttttttaa gtgaagcatc
    26761 tataccactt tggataaaag tcctgacatt tatattttct atttatccta gttttctgaa
    26821 tctgctgatc actttgctat ttaccaacat tgctgctttt ctctatgcac gctttcgact
    26881 aacaaaagct acttttcttg attgtttaaa aacattgatc tattcaattt cattgcctac
    26941 tataattgca acaatcttga tggtctttct tccttctttt gacactagcg ccttcattgc
    27001 ttttgcagga atctttattt ttgctcaagc tgtcaaagga tgggcaaaaa tatcgatcaa
    27061 ttaagaaata aagacaactc gttatttcta cttcaataga cccttttaga ggttgtgaca
    27121 tttttttgtc acagcccctt ttttatttga aaaatatttc tttctcaaaa aacaagcaag
    27181 gcgcttcaaa gttcttcttg tatgcgctac acttagagta aagaaaggcg ggaaattaac
    27241 tatgtcagaa agaatcattt atgcagatcg tccatttcgt gatgaattta tcgaagaaat
    27301 ccatactata gcgcctggtt atatctttaa aacagaatta caaccagagg atctacaaaa
    27361 tgtagagatc agtttgggct ggaactcaga ctaccaagaa aaactattag cctcttctac
    27421 cttgaaatgg gtccaatcta tctcagctgg tgttgatcag ctaccccttg agactttttc
    27481 aaagaaacat attttacttt caaatggtag tggcatccac agtgaatcga ttacggagca
    27541 tgtcttagga atcatccttg ggtattctcg tggtcttttt caagcacaaa aggcacagag
    27601 tgacatgaaa tggttaggtt catcggtcca ttaccaatct atccaaggga aaaaaatact
    27661 aatcattgga actggccata ttggaaaaat gattgcaaaa aaatgcaaag cattagacat
    27721 gaactgctat ggaatcaata catccggtca tccagcagaa ggaatggaaa agactttttc
    27781 tttaaatcaa ctaaaggaag ttcttcctga agtagatttc gtagtcaata tcttacctct
    27841 aacggaggaa acaactgggc tctttgatca gcatatgttt gaacactttg atccaaaatc
    27901 tgtattcatc aatgttggcc gtggtgcttc tgttaagaca caagatctgg tgcaggcttt
    27961 aaataaccag caactttcct ttgcagcatt agacgttttt gaggaagagc ctcttccaca
    28021 agatcatcct ctttggaaaa tggacaatgt actgattact tcccacattg caggtttgac
    28081 acctgatttt caaaagaaat taatggctat ttttttaacc aatctgaaaa gctactttgc
    28141 cacccatgag cttcaaacca atcaagtaaa attgtctgca ggatattaat agctgaaaac
    28201 aatattttca aaagaaaaaa gagaaggtga caaaaattgt gtcaccctct ctttttttat
    28261 tgttttttaa agtgataggt tggctcctcc aggttgggat cataatcaac aagtaaatca
    28321 tatcctttaa agaaccattc atctgcttcc tcgataaaaa aaagtgtccc atcaatttcc
    28381 actttcttta caggatgttc tggctgttca actgacattc caatcgaaaa accatcatga
    28441 acctctgttt tgccgtagac ttttccaaaa aaacgtattc cgtaagtttc tggcagatca
    28501 atttctgagt caaaccactt ttgtgctttt ggcgttaccg ttaatttcat cccaacaacc
    28561 tactttctct tttctttcta ttgattcatc ttatcgtcta gaatatccac atcgcctgtc
    28621 tctccaataa ccagtagatt atcattttca cgaacatatt catctgctgc aggagaagcg
    28681 ataaccgttt gatctactct tcgtatggcg actactgtta agtcaaaacg ttgcctgaaa
    28741 tttaattcag ctaatgtttt gttgaaaaat ttaggattgg agactcggat ttctgctaaa
    28801 gaatatttat ctgacaactc taggtaatct aaaatattct ttgacactaa attatgcgca
    28861 atccttattc ccatgtctcg ctcgggatgg acgacgcgat cagctccgat cttttcaagt
    28921 actctggcat gatactcatt ttgggctttt gctaaaatat ttggtacgcc catttccttt
    28981 accatcagag taactaagat actggcttga atatcttctc caatagcgac aattacatga
    29041 tcgaaatttc ttatgcctaa tgatcgaagt gtcatttcat cctgtgcatt tgccacaaca
    29101 gcatgagtgg ctatattcat atattcattg acccgatctt cattactatc aatagccagt
    29161 acttcttgac cagcttcgat cagtgttcgg cagatacttc cgccaaatcg tccaagacct
    29221 acaattgcaa aattttgttt caccgttttc ctcctttagt atcttctttt ctcagtataa
    29281 caaagccttt acaaaaacaa aagcaagcat cattattgta aaaaagccaa gaaaaataat
    29341 agttattttc tcagcttttg attatcctct ttatcatcgt ttttatttca ccaaaccatg
    29401 tttgaatgca tagatagcgg cttgtgtacg gtcttccact tctagcttag ccaatatatt
    29461 ggaaacatgt gtttttactg ttttcagtgt aataaacaat tcgtccgcta tttcctgatt
    29521 actttttcct tcagaaatca gcattaaaat ttcattttcc cgattcgtta gttcttcatg
    29581 taatacaggc tcatttcgcc gactcatttt ttccatcatt tttgttgtca cttctggttc
    29641 taatactcgc tcgccacgtt gcgttgccct tatagcatca gcaatttcat gtgcggtaga
    29701 ggtcttcaac aaataccctg ctgcacctgc ttcaatggca ggataaactt tttcgtcatc
    29761 aataaaactg gttacgataa tgattttagc ttctggccaa tcttttaaga ttgcttttgt
    29821 tgattcgata ccatccattt cttccatgac taagtccatt aaaatgacgt ccggtcgaag
    29881 tgtcatcgcc ttctcatagc cttgtcgtcc attttcagct tctccaatta cttcaatgtc
    29941 ttcttgaata gataaataaa aagagacgcc taagcgcacc atttcatggt catctactaa
    30001 taaaactttt atcatcctta tctatgcctc cttcatcaaa gggaccttga tttctacact
    30061 tgtaccttga cctttaaaac taatgatttt tactgttcca ccaataccag ctactcgttc
    30121 tttgatattg ttcaatccat aacttcccgt tttcgtttca ttcatattaa accctgttcc
    30181 gtcgtcaata atacgtaaca aaagattatt gtctattttg tgcaaatata cctctaattc
    30241 attggcttta gcatgtctta atgtatttga taacaattct tgaacgattc ggaacaagtg
    30301 atcctcaatg gaactagata gttttacatc ttctacatcc catttcagcg aaatctggat
    30361 tttattttgc aattccttca ataactgctc gataccttgc tttaaacttt tctcttctaa
    30421 attgactgga cgtagatgaa gaagcagcgc acgcatctca gactgggaag cgttgatgat
    30481 ctctgctacc attttcaact gcttgcgaaa catttctggt gtctcgcttt tttctgcttg
    30541 ctccgtcaat gccgacatca tcatcattgc tgcaaacaat tgttgcgaaa ctgaatcatg
    30601 cagctcacgg gctaatcgat gtctttctaa ttctaaaatt tcttctttgg tttgtccatc
    30661 tacatattgg ggacggctcg ttacaatttg taattcacta gatacttcaa tcattttttc
    30721 ttttatctta gtgatttcct tatcaatatc tttgatgtat aaatcgtccg atgcacttgg
    30781 gatcggaaga agcaacaatt tggattcata attgccagaa gaaagtgcac gcagcttttc
    30841 ttcgattttc ccgtattttg tcttttgaat aagtgataat aatagaaaga caattaatcc
    30901 tacacctaag gaaatggcta acaaatggaa gataagcgga acatataata aacgtgcacg
    30961 cagtaattct ccccaccaat gactttgatt gctggcataa aaataagtga aaagtgaaaa
    31021 tagaataata aggaaagccg caatccccga ataaacagct agcatcgctc tggatatttt
    31081 tcccatcata ttcgtatcac ctcgacatct ccaatcaagg tattagtaat aatcttcaat
    31141 ctacgagggt tttcatcata atcactgctg tagattttga tttgttcatt tttcaaagaa
    31201 aattgctctt cttcaaacaa gacatttcct actaatgtcg catgctctaa tcggatggct
    31261 acgcccaaag gtactaagat ccgtgttctg cctatccctt ttcttacaat cacaatatta
    31321 tcatcttttg gcaaaagcgt attgcccaaa tctatgatag tatcaccaga aatgacggcg
    31381 atgttgatat cgtcccattc atagacgtcg tttccaatac gttggttacc gaataattgc
    31441 tgtcttttcc gctcattatt atgtgttttt aattgctctg tttggatcat catgatctgt
    31501 ttctttcgcc aaaaagcatt tttggttaaa tctatccctg aaatctctac acctttcaga
    31561 ccaataaata aaacggcaaa tacagccatc atccataaag caggactgtt gactaagcta
    31621 aaaaaaatga ccaaacttcc taatatcaat tgaaaatttt gaaatttagt acgaggatgt
    31681 ttgcgcatag ctagatatat attgaaaata ccgaatatca ctaaaagcaa aagtccagta
    31741 ttgtttacga tttgccaaac agcaaataac agcagtagtg cttcaactac cacaaaaaaa
    31801 cgccaagaac tattcatcgc tctttctccc tcctgacaca ttctcatttc atcataccta
    31861 tttttttaac tgttggctat aggactttag atgtaagatc gtttgttgaa atctaaaata
    31921 cacaaagaga aaaagatcta gagtgtatca tcagtaagat gaactctcta gatctttcag
    31981 tcagactacg cttgttctac tttgacgatt ttaactaaca tatcgccacc tggagtagca
    32041 atagttactt catcattttt acgtttgcca atcaatgctt gcgcaatagg agaatcattg
    32101 gaaattttgc cagaaaacgg atctgcttca gcgcttccga caatcgtgta ctcttcttct
    32161 tctccatctg gtagttcgat gaatgtaact gttttaccaa ttgatacctc atctgcatct
    32221 acaccgtcgt tatcgatgat ttgagcaaaa cgaatcatat tttcaattgt tgtgattctt
    32281 ccttcaacaa atgcttgttc atctttcgct gattcatatt cagagttttc ggaaagatct
    32341 ccgaaaccgc gggcaatttt gattcgttca atgatttctc cgcgtttgac tgtttttagt
    32401 tcttctaatt ctttttctaa tttttcttta ccttctagag tcattggata aactttctct
    32461 accatgtgta acgtctcctt ttttcgataa aataccgcaa aaggtaatct tttgaggaat
    32521 atagtccaaa aaagattacc acgcttttct tcaaatgtaa atgtttttct aaaaatgatc
    32581 aatgtctaga gcctgttttt ctaagaatta tttacatatt tttccactaa ttccatatgt
    32641 tcttcataag ttttagcgaa ataaacattt ccagtgctcg tatctgctac gaaataataa
    32701 tagtcatttt ctgctggttc taatactgcc ttgattgcct cttcgcttgg attgtcaaaa
    32761 ggtccaggtc catagccggt attggtatac aaattatatg gtgaatctac agctgtatct
    32821 tcatacgtca ctaattcttt gtgttcacct aatgcgtata aaacagagat atctgactga
    32881 agtggcatat ttgctttgat tcggttaaag aagacttgtg caatgttttt acgatcattt
    32941 tcttttacgc cttctttttc aactagagaa gctagagtta aaacttcttg tacagtcaaa
    33001 tttttctgct tgatagctga ataatagttt tgcatgaccg tattcgtctt gttcaccatt
    33061 tcaatcacta gatccttaag cgaagtactc gtgtaataat catatgtggc tgggaataag
    33121 taaccttcca aacggtattt tgtgttctca gctttagatg cactttccaa cagttctggg
    33181 aatttttggt gcaactcgtt aaagaaagtc tcatcattca ctaaatctaa aaattctttc
    33241 ttgtctttac cagttacctt cgctacccgt tcagcaatct gatcgatatc gtacccttct
    33301 ggaatggcaa ttttcccatc tgcaactttt gttggctcag aagtaccgcc ttcttgcaac
    33361 tgtttgccaa tctcgtcaag agtcatatta ggcgctaact gataatagcc agcttgaaag
    33421 ccagttaaat ttttaaattt tgtataataa ttgaaaacaa tcccgctttt aataatattg
    33481 tccttctcca aaatctcacc aatctgcttg ttagaagagc cactcgggat ctcgacttgg
    33541 actaattggt catctgattt atctaaaggc ttcaacccgc tatctacata acgatacacg
    33601 gtaaatccaa gaaatccgcc aataatcaat aatgtaagag caatcactaa aatgatcttc
    33661 ctcacaatct tatcttcttt tttacgcaga tttctccgct tgtcgattat atctgctgta
    33721 gctgccttac tggcttcttt tttatcttta cttgggtgtt gtttgtttcc tgacaaaaca
    33781 actcctcctt actatcaagt tcgtaacttt attcattata catgatattt gaattggcgt
    33841 gaatgatttt atttaaatat tctatcaaaa atgtaagtag taaatccatt actataagat
    33901 taaaataaat gttatcaaga tacaagctat tttagcttta ttctttctgt aaaaaagaaa
    33961 ggagactaaa taaactatta tgaaaaaagg aaaacatgct aaaaaaagaa aatattcatt
    34021 tttaatgatc gttgtcgtgt tgtttagcct tagtgcgttc tctacaggaa ctattcttgg
    34081 atggcaattt tacaataatg aacactctca gatagttgcc catgctcaat cagctcaaaa
    34141 aaagttgata ctgactacca atgaacaaca gctcgttgaa aaaatcgatc aactattaag
    34201 aaaaaatgat tatattggct caatttacgt aaagaaaaat aatcgcatca tcatggaaaa
    34261 aggctatggc tatgcgaata aactcacgca acaaccaaat gatccttctc tttattatca
    34321 gattggttcg gttcaaaaag cattgactac tcttttgatt ttaaaacaag tcgagcgtgg
    34381 gcacctttct ttagatacta agctggctca attctatcca caaattgctg gcagccagca
    34441 aattactatc cgtgacttgc tgtatatgcg ctcaggcttg caccgaactg cttctccaac
    34501 cataccgatg actgatgaag aagtcgttca atttgcgatt cagcacttaa aatttacaga
    34561 ttatcagacc tctcattatg attcattgaa ctttaccata ttgactggaa ttttgatcaa
    34621 attaacaaat caaccgtatg aaaaattatt gaccgatgat atcatcgaac ctttaggatt
    34681 acagcataca aaattttatg accaagtcaa aaattcatcc aatcatgcac tatcctatca
    34741 aatgtctaaa gaggatgatt actttaaacc actgacagaa tctgaaacag agatccataa
    34801 cgaattaggg actggtaata tcagtatgtc cgtctatgat ttaaatacgc tgtttacaca
    34861 agttttatct ggaaaactag tttccaaaga cttactcttc tcattatggc gtgaaaatgc
    34921 gaatggacat ccatatagtg gtggggtata tagcggagat aattatatcc tgtcgcaagg
    34981 aaatatcgac tcttttgata catctgctat atttagcaaa gattcacagg atgctatcat
    35041 catggaaagc aatataaaag ctgacaaaac tatcaaactg cctactgctg atctaagaaa
    35101 ccaaatctat gacctgatgg aaggaactac taagttggca aatagctgat atgatgaaaa
    35161 gatagcaaat actacttctt tgaatagcat ttgcttaaaa aaagtactcg actaaacgta
    35221 ggaaagagtg tgggacaaat ctaaaaatca atttttgcta cagactttaa ttccaaataa
    35281 acagaacaga aagaggtgtt cttctttctg ttctgtccaa attattctaa gatttctctt
    35341 taccaacatt atttgacaaa gggcctatta aatctaaaat agtatcttta gattgctaaa
    35401 atatgtgcta gcaaatcatt catggcttgt tcttattttt aattttatgc aataaaaaag
    35461 aagaacaatt agcgtgatta tagaaataaa taatgagatt ttagaaaaaa atgtgtatga
    35521 atacctgatt gttactttat ttattccact ttcacttttt actgtaacaa aaggacctcc
    35581 ttgttttagt actgtagcat tttttgaatt aacagtaacc gttaatcctt tataccggaa
    35641 tacaggtaaa actattgttt tgccttttga agatttaaac gtaaatgtaa tttcatcttt
    35701 atttggagaa aagctactat aaataacttg accatcttct gtaacttgat ggtttttcaa
    35761 aagcaattga tcttttttat agcctatagg tacataatca aaattctcaa attcttcaag
    35821 tttattttcc atttgttcat tagaataagt tccttgaaaa ttcatttctt tcaccatgtt
    35881 aactactgat gaataattta aaattgaaat agctaatatt aataatagta taaaatttct
    35941 tctccttgta taagaaaatt tttccaactg tggagaaata aatagagata ctgaaaaaga
    36001 tatgaacaat gttgaaaata tcataaaacg ccaaggagct tgaataatat ttaaaggagt
    36061 attttgtaag gcaaaccatg gaaatatttt tgtacaaagt agaatagata ttatacccat
    36121 tatataagtg attttagata agattcctaa ttttttaaag ttaaatgtta gtataattaa
    36181 acaaataagc aaagttaagc caataccaaa tgatagtaat tctgaatcta tacttccaat
    36241 caaaaactct ttacccagat aaattgctct tttttgtaat atatccacat aaggtctatt
    36301 cagatcttga tacaatgtct gctcaatcat aggacctata aacgctagtg aaagaagtaa
    36361 agtaactata gcagctttta ttaatttaat aattaagaag atttctattt tctttttccg
    36421 ataaaattga ataattaaag caattataat cattaccata gtcatagcta cagaaagaac
    36481 atgagtgtaa attaataaag tcatgctaat cgccaacata acccaagatt ctttttttga
    36541 gtcgtaaagc tttataaacc cgagtaaaat aagaggaagt attgacattg cgagtaattc
    36601 ccccattgcc cctcgaagaa atatttctac actcctaaaa gaagatgttg tatatataat
    36661 agcgaaaaag gagctagtaa catgtttttt ggtaatttca tacattacat aatgacatat
    36721 aaatagagta atgagcgtaa caatataaag aaaaaggtta tagcctattg ctaaattagt
    36781 aaacttgatc aataaaaata aaggatatag agttaaccat gggtaaaaat tatttacttg
    36841 catgccatat gatctaaacg tttcaaaatt aataggggag ctaaaaatag attctaaact
    36901 taacgcacga ttaatgtgaa atgccgtatc ataaaagcca aatatttcca tgtttttaaa
    36961 tgctggaaat aaatataata aactaacaaa tgcataaact ataaatattt ttacagaaaa
    37021 aatttttttc aaattcatat accacctcat gtttttttat attacatata gtatcattta
    37081 ttttttttaa acactagatt agtcactata taaaatgtga ttaattttat tattaataaa
    37141 atatttttta tattacaaaa gtagtgttt
//
LOCUS       DACGEU010000016        37076 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.016, whole genome shotgun sequence.
ACCESSION   DACGEU010000016 DACGEU010000000
VERSION     DACGEU010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 37076)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37076)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37076
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.016"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            320..1981
                     /locus_tag="IXR40_000780"
     CDS             320..1981
                     /locus_tag="IXR40_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HAQ4360650.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(2051..2398)
                     /locus_tag="IXR40_000781"
     CDS             complement(2051..2398)
                     /locus_tag="IXR40_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HAQ4360651.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSTLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            2482..3423
                     /locus_tag="IXR40_000782"
     CDS             2482..3423
                     /locus_tag="IXR40_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4360652.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            3424..4467
                     /locus_tag="IXR40_000783"
     CDS             3424..4467
                     /locus_tag="IXR40_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4360653.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            4473..5543
                     /locus_tag="IXR40_000784"
     CDS             4473..5543
                     /locus_tag="IXR40_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4360654.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            5533..6486
                     /locus_tag="IXR40_000785"
     CDS             5533..6486
                     /locus_tag="IXR40_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAQ4360655.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            6498..7508
                     /locus_tag="IXR40_000786"
     CDS             6498..7508
                     /locus_tag="IXR40_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAQ4360656.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(7793..8614)
                     /locus_tag="IXR40_000787"
     CDS             complement(7793..8614)
                     /locus_tag="IXR40_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HAQ4360657.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(8711..8989)
                     /locus_tag="IXR40_000788"
     CDS             complement(8711..8989)
                     /locus_tag="IXR40_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360658.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            9257..11266
                     /gene="metG"
                     /locus_tag="IXR40_000789"
     CDS             9257..11266
                     /gene="metG"
                     /locus_tag="IXR40_000789"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HAQ4360659.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(11745..12332)
                     /locus_tag="IXR40_000790"
     CDS             complement(11745..12332)
                     /locus_tag="IXR40_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360660.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            12507..13829
                     /locus_tag="IXR40_000791"
     CDS             12507..13829
                     /locus_tag="IXR40_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAQ4360661.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            13984..14760
                     /locus_tag="IXR40_000792"
     CDS             13984..14760
                     /locus_tag="IXR40_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HAQ4360662.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            14753..15322
                     /gene="rnmV"
                     /locus_tag="IXR40_000793"
     CDS             14753..15322
                     /gene="rnmV"
                     /locus_tag="IXR40_000793"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HAQ4360663.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            15315..16199
                     /gene="rsmA"
                     /locus_tag="IXR40_000794"
     CDS             15315..16199
                     /gene="rsmA"
                     /locus_tag="IXR40_000794"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HAQ4360664.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            16650..17279
                     /locus_tag="IXR40_000795"
     CDS             16650..17279
                     /locus_tag="IXR40_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360665.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(17403..18512)
                     /gene="ugpC"
                     /locus_tag="IXR40_000796"
     CDS             complement(17403..18512)
                     /gene="ugpC"
                     /locus_tag="IXR40_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HAQ4360666.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            18721..19143
                     /gene="mgsA"
                     /locus_tag="IXR40_000797"
     CDS             18721..19143
                     /gene="mgsA"
                     /locus_tag="IXR40_000797"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HAQ4360667.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     gene            19466..20002
                     /locus_tag="IXR40_000798"
     CDS             19466..20002
                     /locus_tag="IXR40_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HAQ4360668.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(20042..21805)
                     /locus_tag="IXR40_000799"
     CDS             complement(20042..21805)
                     /locus_tag="IXR40_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4360669.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(21808..23523)
                     /locus_tag="IXR40_000800"
     CDS             complement(21808..23523)
                     /locus_tag="IXR40_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4360670.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
     gene            complement(24302..24526)
                     /locus_tag="IXR40_000801"
     CDS             complement(24302..24526)
                     /locus_tag="IXR40_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360671.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            24726..27494
                     /locus_tag="IXR40_000802"
     CDS             24726..27494
                     /locus_tag="IXR40_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAQ4360672.1"
                     /translation="MLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNTVSH
                     YLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQPKDL
                     FSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLHDLL
                     EDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLDEVH
                     RLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRIPIR
                     IELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGELKNI
                     VKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLMEKQ
                     QPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHELLVY
                     WTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELEQQV
                     SQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIAAHG
                     YATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILVDMG
                     SLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPEWRL
                     LYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNSDPL
                     FSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQRII
                     RNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLIERL
                     IRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSEDTE
                     FLSIEEEF"
     gene            27575..27994
                     /locus_tag="IXR40_000803"
     CDS             27575..27994
                     /locus_tag="IXR40_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HAQ4360673.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            28006..28476
                     /locus_tag="IXR40_000804"
     CDS             28006..28476
                     /locus_tag="IXR40_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAQ4360674.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            28493..29272
                     /locus_tag="IXR40_000805"
     CDS             28493..29272
                     /locus_tag="IXR40_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4360675.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            29259..30080
                     /locus_tag="IXR40_000806"
     CDS             29259..30080
                     /locus_tag="IXR40_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAQ4360676.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            30097..31146
                     /locus_tag="IXR40_000807"
     CDS             30097..31146
                     /locus_tag="IXR40_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAQ4360677.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            31159..32163
                     /locus_tag="IXR40_000808"
     CDS             31159..32163
                     /locus_tag="IXR40_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAQ4360678.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            32796..33815
                     /locus_tag="IXR40_000809"
     CDS             32796..33815
                     /locus_tag="IXR40_000809"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HAQ4360679.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
     gene            33858..34739
                     /gene="galU"
                     /locus_tag="IXR40_000810"
     CDS             33858..34739
                     /gene="galU"
                     /locus_tag="IXR40_000810"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HAQ4360680.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
     gene            35039..35416
                     /locus_tag="IXR40_000811"
     CDS             35039..35416
                     /locus_tag="IXR40_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360681.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            36022..36636
                     /locus_tag="IXR40_000812"
     CDS             36022..36636
                     /locus_tag="IXR40_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAQ4360682.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
BASE COUNT        12136 a         6497 c         7577 g        10866 t
ORIGIN      
        1 tggcttttga acaccgttta ttcagataag ggactgtgac aagacttttg tcacagtttc
       61 tttttgttta ttctttttta tctttgtatg gcaataatag acaatataac gaaaattatt
      121 taatggcttt tggaagacca tggaaaacct tgtacaaagc tattttttct gaaaaattcc
      181 ttgaaacctc acgaaaaaat cattatttta tgaaaaagac aaaaaaaagt gttgattttt
      241 taataattat tcattaaact cttaaacaac ttcagaaaat attaattatt ctgaaaattc
      301 caataaaggg gtacgtaaaa tgaaaaagaa atttacattt ggtttggttg cggtatgcgg
      361 ccttgtactt gctggatgtt atggcggcag ttcagccaca agcagtagtt cagcaaaaag
      421 cggttcagca gatggaggag gcgtatttaa cttagtcgtg cctcaagaaa tgcctacagc
      481 tgacttatca gttgcaacag atacaatcag ttttacagca ttgaataacg tttatgaagg
      541 aatttaccgt cttgatgaag acagcaaacc acagccggca ggagctagcg agttggcaga
      601 agtcagtgaa gacggattaa cttacaaaat caaattacga gaagacgcaa aatggtcaaa
      661 tggtgatcct gttacagcag cggattacgt ttatggctgg caacgaacag tagacccagc
      721 tacagcttct gaatatgctt acctgtatgc gccagttgaa aatgcagaag acattacagc
      781 tggaaagaaa gataaatcag aactagggat caaagcagtt ggtgactatg aattagaaat
      841 caaattgacg aaacaaacac catatttcca atatctgctt gctttcccat catttttccc
      901 acaaaaacaa tccgtagtgg aagaaaatgg ggatgcctat gcatctgcaa gtgataaagc
      961 tgtttataat ggaccattca cattagaaga ttttgatgga ccaggaacag atacagaatg
     1021 gacttataag aaaaatgatc attactggga caaagataca gtaaaacttt ctgaaatcaa
     1081 agtcagtgta gtaaaagaat cttctactgc attgaactta ttcaaagatg gccaagcaga
     1141 tgacgtgatc ttgtctggtg agttagcaca gcaaaacgca aacgatccag cttatacttc
     1201 tgttaaagaa gcgcggacaa gctatatcga attcaatcaa cgtgaaaaga attcaccatt
     1261 caacaatgtg aacctaagaa aagctatttc ttattctatc gatcgtgaag ctttagtaaa
     1321 acaagtacta ggtgacggat cagttgtctc tacaggattg atcccatcag atatggtaaa
     1381 aagtccaaca acgaacgaag actttgcaaa agaagctgga aaattagttt cttatgacaa
     1441 agataaagca aaagaatatt gggaaaaagc gaaaaaagaa ttgggcgttg attctttaga
     1501 atttgatttg atggcttctg atgatgattc atcgaaaaaa gtaatcgaat atgttcaaaa
     1561 ctcaatccaa gaaaacttgg atggcgtaac agtcaaacca acacctgttc cattctctgt
     1621 acgtcttgac cgctcaactt cgggtgattt tgacgcagta ctaggcggat gggctgctga
     1681 ctatgcagac ccaagcagct ttactgattt gtttgtcaca ggtaattcat acaaccgtgg
     1741 tcgctggagc aatgcagaat atgacgaagc agttaaagca gcttcatcaa cagacgctgg
     1801 cgatgaacaa gcccgttggg atgatttcca aaaagcaatc aagatcatct ctgatgatat
     1861 gggtgtcgtt ccggtgtacc aaaaagcaga aggtcaccta gtgaatgaaa aaatcaaagg
     1921 tatcgttcac catgcggcag gcgcttcatg ggattacaaa tggacatacg ttgaagaata
     1981 atcgttaata ccgtgagcat gagaaaaaac gaggctgcgg caaatgtcgc aacctcgttc
     2041 tcatattcac ttatcctaac aaagaaaaaa gcatgaaaat agcagaaaga gcaattagta
     2101 ttccggcaat gatcagccaa aagctgtaca taccgtagct ggcagacgag agcgtggaaa
     2161 attctggttt tttctttcgg ttccttgttc gtgcaagatg gaccgatcgc tgaaaatgat
     2221 cgaagaaacc cgaagaaaag acccataaaa aaccgccgat aatcagaaac ggcaatgacc
     2281 ataagaatag atcattagat aattgaatga gtgtaaagga atggttgatg agatttttta
     2341 ttaaaataac cagaatcagt agaaaagcta ctgcgtaggg gatagatttt tttttcattt
     2401 gattgctcct ttatttttgg ttcattatct aataatgtag cgaaacatct gtcagaagtc
     2461 aaaagctagg gggaaacatt agtgaatagt tatatcaaat atgtattaaa acgtgtcttt
     2521 ttcatgatca tcacgctttg gttaattgca acaatcacct ttttcttgat gcaattgctg
     2581 ccgggcacgc catatacgaa tcaggaacgt ttgagtcctg aaacaatcga gatgctaaat
     2641 aaacaagtcg gtttggataa accagttatc gtacaatatg ggatttatct ttctaatttg
     2701 cttcaaggag attttggaat ttccttccaa tttaaaaacc agccagtcgc acatttgtta
     2761 gctggaagaa tcggaccatc cttgcagtta gggttacagg caattatctt tggaacagtc
     2821 ctagggacga ttttaggaac gatctctgcc atgaagcaaa atacatgggc agatacatct
     2881 tctacactcg tagcgatatt aggtcgttcc attccaaact ttgtatttgc tgttttatta
     2941 caatatatct ttgcaatcaa attacaagtt ttgccaatcg caaaatggga tggctttgtg
     3001 tacacaatct taccaacaat tgcgttggcc atgtcgccgc ttgctgactc tgctcggttt
     3061 atccgtacgg aaatggtgga agtactgcat agtgattatg tggaattagc aaaagcaaaa
     3121 ggattgagcc gttgggaaat cgcctttaaa catggtcttc gaaatagttt gattccattg
     3181 atgactttat taggaccgtt agctgtagca ttgatgaccg gatcactggt ggtagaaaat
     3241 atctttgcta ttcctggtat cggggaacaa ttcgttaagt caatcacaac aaatgattat
     3301 cctacgatca tggctgtaac gatcctttac tcatttatgc tgatttttgt tattttgatc
     3361 gtggatctat tgtacggtct agttgatcca agaattcgtg tttcagaagg gagccgagga
     3421 taaatggaaa tgataccaaa gcgttatgaa acagttgcag atatccctgc ggatgaattt
     3481 cttccattac aaaaaaatac cgaagaagaa cgtgaacaga ttactgcacc ttctttgaat
     3541 tttatccaag attcatggcg ccgtttaaag aaaaacaaag ctgccgttat ttcaatggtt
     3601 ttactattgg tcatcatttt gatctctgtg atcacaatct ttgtttctcc tcatgatcca
     3661 actgcccaaa acgtggctta tatcaatttg cctcctcgta ttccgggaat caatatcgat
     3721 ggattgaatg gaaaagcaat ggttggtggt gaacttgttg ataaatatgc tcaagcaaac
     3781 gtcccttcaa acgtaaattt ctttttagga acagacggtt tgggacgtga tgtattaagc
     3841 cgcttattta tgggaatgag aatctcgttg ctgatcgcat ttattgctgc attactagat
     3901 gtaacgattg gtgtagctta cgggttggtt tctggtttgt taggcggacg tgtcgataac
     3961 gtgatgcaac gttttttgga aatcttatca ggaattccaa acctcgttgt catgattttg
     4021 atgttggtcg tttttgaacc aggaattttt tcaatcgtgg ctgctatggc catcacaaac
     4081 tggataccaa tggcacgtat cgttcgtgca caaacaatga aattaaaaga tcaagaatat
     4141 gttttagctg gattgacatt aggtgaatca agaatgaaaa ttgcattcaa acatattttg
     4201 ccgaatatct ctagtgtcat tattattcaa atgatgttta gtattccatc tgctattttc
     4261 ttcgaagcct ttttaagctt tatcggttta ggtcttacgc ctccgtcagc ttcattagga
     4321 acgatgttga gcgaagggta caagacattc ctgtatctgc cttatctatt atggattccg
     4381 gcagtaactt tatcggttat catgattggc tttaacttac ttgctgatgg attgcgtgat
     4441 gcctttgatc ctaaaatgaa agagtgaaga cgatgacgaa aattttagaa gtgaaagact
     4501 tagaaatctc ttttgatacg tatgctggaa aggtacgagc gattcgcggt gtcaattttc
     4561 atttgaataa aggagaaaca ttggcgatcg ttggggaatc tggaagtgga aaatcagtga
     4621 cgaccagaag catcatgcgc ttgctgtcaa gcaacgccaa tatagatgct ggtcaaatcc
     4681 tctttaaagg taacgatatc gttggaaaat cagaaagaga gatgcaaaaa atccgtggta
     4741 aagaaatagc gatgattttc caagatccaa tgacctcttt agatccgacg atgcccattg
     4801 ggaagcaagt cgctgagtcc cttagaaagc ataataaagt ttcaaaaaaa gagggacaaa
     4861 aagctgcatt agaattgctt aaattagttg gaatacccga agctgagaaa cgtatcaaca
     4921 gttatccgca tcagttctca ggaggtcagc gtcaacggat cgtgatcgcg attgcactgg
     4981 tatgttatcc ggaaatcctg attgctgatg aacctacaac agcgcttgat gtgactattc
     5041 aagcacagat tttggagctg ctgaaagaaa ttcagacaaa aatcgataca tcaattatct
     5101 ttatcactca tgaccttggt gtagtagcga atgtcgctga tcgtgtcgct gtcatgtatg
     5161 gaggaagaat cgttgaagtt ggaacatcgg aagaaatttt ctacaacccg caacatccct
     5221 atacttgggg actgcttggt tcaatgccga cattagatag tgcgaacgat cgattgtatg
     5281 ctattcctgg ttctccaccg gatttattga acccgccaaa aggagacgca ttctatccaa
     5341 gaaatgaatt cgcgatgaaa atcgatgcag aacaagaacc accatttttt gaactatcaa
     5401 aaacacacaa ggcagcaact tggctacttg ctccgcaggc acccaaagtg acaccgccag
     5461 aagaaatcca acgtcgctgg gctatcttta aagagaaaca aaaacatact tacggtcaag
     5521 gaggaattgc tgatgccaaa taaactactt gaagttaaag gattgaaaca gtatttcaat
     5581 gtaggaaaaa agaatgaagt acatgctgta aatgacatca gctttcacat ttatgaagga
     5641 gaaacattcg gtttagttgg agaatctgga agcggaaaat ccactactgg ccgtacgatc
     5701 attcgcttga atgaacctac tgatggtgag atattattcg acggtcaaga tataacgaag
     5761 atcaaagata aaaaaggttt gacgaaattc cggcatgatg ttcagatgat ctttcaagat
     5821 ccatacgctt cgttgaatcc tcgtatgaaa gtcagagata tcattgccga aggaattgat
     5881 gttaatggac tagctaaatc atctgaagag cgtgcaaaaa aagtcgatga tctattgaga
     5941 actgttggat tgaatccaag ccacggtact cgttatcctc atgaattttc aggtgggcaa
     6001 cgccagcgta ttggtattgc acgagcattg gcagtaaaac cgcgttttat catttgtgat
     6061 gaaccaattt ctgcactaga tgtgtcgatc caagcccaag tggtcaattt gttgcaagat
     6121 ctccaaaaag aacatcaatt gacctatcta tttattgcac atgatttgtc gatggttaaa
     6181 catattagtg accgaatcgg tgtaatgcat aacggcttgt tattagagat gggaacaagt
     6241 gatgaaatct ataatcacgg tgttcatcct tatacagaaa gtttgttatc tgctattcct
     6301 ctaccagatc cagaccatga gagaaaacgc agaagaatca aatatcaacc tgaaccagat
     6361 gacggacaag tacgtcaact tcgtgaaatc gcaccagaac attttgtcta tgcaactgag
     6421 caggaagtcc catattacgc aaaaaaacta aaacgacaaa aggaatctct tctggttgct
     6481 aactaggagg gacatagatg ctaaaagctt ttaaattccg tatgtatccg acagaagaac
     6541 aaaaacagca attgattcgt acttttggat gtgctcgatt tacctataac catttgctga
     6601 aaaagcggca gaaaagttgg caacaaacag gagtagccaa tttttcgctc acacccgcta
     6661 cattaaaaaa agaataccca ttcttaaaag aagtagacag tcttgcttta gcaaatgcac
     6721 agcttaattt ggatcgggct tttcgcaatt atttcaaggg acgtgccagc ttcccaaagc
     6781 ttaaaacgaa aaaaagtatg tggcaatctt atacgaccaa caaccaaacc cgtacgatct
     6841 atctggaaaa tggctactta aagttaccaa aacaaaaaga actaatcaag ataaatcagc
     6901 atcggccagt tgaaggatcg attcgctccg ctacgatttc tgctcgatat aatgaagaat
     6961 tttatgtcgc actactttgt gatgtttcgc cagtaaaaaa agaatcttta gctaaatgga
     7021 tcgggatcgc ctatcatccg aagacattga tccaaacatc tcgacctcta gaagtaactt
     7081 taccaaaatt tcaccagaca gaagaaaagc tgcaacatgc acagcggaaa ttgaatgtga
     7141 aagtccgctc cgctcaccat agaaagatca ggttagatca ggcaagcaat tatcagaaac
     7201 aaaagagaaa agtaatggat ctttatctga aacaaaagaa ccagcgagaa gattatcttg
     7261 aacaattatc tgggaaattg gtcaaacaat atgactactt atttgtagaa tcttttccaa
     7321 aagaagaggc acatgctgat ttttctattc acgactggca taaattaata acaaaattgc
     7381 gttataagtc ccaatggtat aataaaaaat ttcttttgat caataccgac ggagcagaag
     7441 aaagcaattc cgtaagaaag agccaagtag tagaaaaaat gggcagacat tcggttatca
     7501 agggataaaa aatgaatgaa actgatagga gcgttagggt tagccttgtt aataaaaagt
     7561 cttaatgact tttgtttcta ggaatttttc ttttgaagaa aagctcacta attatgacaa
     7621 accaataaaa caatagcaga aaaagttcgt acgagctttt tctgctattg ttaatttttt
     7681 attcagaaag tttacgaata catcaaaatt ctgaaacaaa aaacgtaact cacaaagagt
     7741 tgtttttgcg ttttttcttg aatgattagg tctgaatctt ttgctcacaa ccttattcat
     7801 ggtgccccgg cttgagctga tagatttttg aaggacggcc gattcctaca ggacgttcac
     7861 cgatctcatc gaaatattgg agcatagctt tcttaaaatt ggaatgatcg atcgttttat
     7921 aatcgatccc taagaattta gcaaatactt ttcgagcttc cgtaatcgtg aaatctttac
     7981 ctaaaacttg tagaacttgc ggctcgtgtt ccattttatt gactacacgg ttgaatgctt
     8041 tcaagatgat ttgactatgg tcaaaagcca aagtatcttt gccagaagac tctccagtga
     8101 ctaaatcaag cgagatagcc acttctccgc tagataaatg gatcttgtta ctatgacgtt
     8161 ctagtgtgaa ccagcgtact tccttggcat catctccggc gattagcggt tcttctccaa
     8221 taaaggctaa gtagctgact gtgacgaccc agcctcgcgg atctcgatta ggcgtactga
     8281 atgtatgcag ttgctcaata ttttcttttg aaataaccac accagtttct tcctttgttt
     8341 ctcttaagac gctttctcca gttgactcat ccttttggac aaagccacca ggcaatgccc
     8401 atgaatttcg ataaggatgc ccttttcttt ggatcaacaa aactttcagc tgatcttctt
     8461 ctttgttata gcacatcagt acgatatcga cagtcaaaga gggcttgtca tattctggac
     8521 gttcctgttt ttgataccag ttaagaaatt cttcttcact tgctttatgt tcataatata
     8581 atttttcttc ttctttagaa gcaaaacggt tcatctgacc acctccattg acagtaaaag
     8641 tactttttac cttattgtag cagactctga aaaaaaacca aggatttact tgaaaaatct
     8701 aggttatcat ttaaatatga aaaataaatg gaagtatgag attgaataaa aagaaaagca
     8761 gataaaacgg caatacttta taccgctctt cacgaatggc aaagaagcca caaataacga
     8821 tatatacgtc aatgataaaa cgcaaaatcc aagctgctgt cataaaactg ttcaaatgcc
     8881 catggaggtt aaaataacca tacatacgaa tataaaaata gctgaatatt aaatgtgcta
     8941 atgaaagaaa agcaatacta agtgtaaaaa aaagatgttt cttctgcatg attgttccag
     9001 tcccttacta agatagatag tctttattat accacgtgtg aggggagaaa taaaaagccg
     9061 ttttttagta gatatgaaac aaaacaaaaa cccgcattta ttcaacctat tcatcctttt
     9121 aaaggataga ttgaacgtag atagaagtcg tttatccagt ctttttcatt ttgaaaaaaa
     9181 gctaacagca tgcttttttt atggtatact agcaaggaaa cgaattcgca tcatgcgata
     9241 aaggaggaag agccccgtgg cagaaaagga aactttttat atcactacgc caatctatta
     9301 tccaagcggc aaacttcata tcggcaactc gtatactacg attgcatgtg acgcaattgc
     9361 tcgttataaa cggttgatgg gctttgatgt gttttatctc actggagtgg atgaacatgg
     9421 tcaaaaaatc gaaacaaaag cagaagaact aggtgtaaaa ccgcaagaat atgtagataa
     9481 aatggcggct gatgtcaaga aattatggaa aacgcttgat atcagttatg ataaattcat
     9541 tcgcacgaca gatgattacc ataaagcagc tgttcaaaaa atatttgatc gtttattaga
     9601 acagggagat atttacttag gtgaatatga aggctggtac tctgtttctg acgaagaatt
     9661 ctttacagaa acacaacttg cagaagtgta caaagatgac gaaggtaacg tgatcggtgg
     9721 taaagcgcca agtggacacg aagtagaatt ggtaaaagaa gaatcatact tcttccgcat
     9781 gagcaaatac gcagaccgtc tattggaata ctatgaagaa catcccgaat tcatccagcc
     9841 agaatctcgt aaaaacgaaa tgatcaacaa ctttatcaaa ccaggattag aggatcttgc
     9901 agtttcacga acaactttta cttggggagt accagtcaag agtgatccga aacatgtggt
     9961 gtatgtatgg atcgatgcat tatccaatta tattactgca ctaggatatg gctccgaaga
    10021 tgaaagtcta ttcgaaaaat actggcctgc agatgttcag atggtcggta aagaaatcgt
    10081 tcgctttcat acgatctatt ggccaatcat gctgatggcc cttgatttgc ctctacctaa
    10141 aaaagtattt gggcatggct ggctattgat gaaagacgga aaaatgtcta aatcaaaagg
    10201 aaatgtcgtt tatcctgaaa tgcttgtgga acgttatggt ttagatgcac tccgttatta
    10261 tttgcttcgt gctgttccgt ttgggtcaga tggtgtcttt acgccagaag attttgtttc
    10321 ccgtgtcaat tatgatctgg caaatgatct agggaactta ttgaatcgaa cgattgctat
    10381 gatcaacaaa tattgtgatg gactcgttcc tgactatgcc tcacttgtca ctccatttga
    10441 tagtgaactg tctacgacgg ctgctaacgt tgtcggacgt taccatgatg caatggaaaa
    10501 aatggaattc aatacagcat tggctgaaat ctgggtgctg atttctcgtg caaacaaata
    10561 cattgatgaa acagaaccat gggtattagc aaaagacgaa gaaaagaaag ctgaattgaa
    10621 tagtgtcatg atccatttag ctgaatcttt gcgtatcgca gcgatattac ttcagccaat
    10681 catgacagaa acgccagaga agatcttcaa tcaactagga ttggactctg aaacaatgaa
    10741 tcttgaagga ttacactttg gcgaatttcc ttcaggaaca aaagtagttg caaaaggtac
    10801 accaatcttc ccacgtttag atatggaaga agaagttgct tttattcaag aaaaaatgtc
    10861 tgaaggtact caaacaaacg aagatacagt caaatgggat ccagaagaaa cagaacttgt
    10921 ttcaacgaaa gaaaaacaaa tcaaatttga tgtatttgaa aaagtagaac taaaagtagc
    10981 agaagtcatc aactgtcaaa aagtagaagg ggcagataag ttgctgcaat tccgactaga
    11041 tgctggagac agccaagacc gtcaaatctt gtcaggaatc gctgaatttt atcctgatcc
    11101 aagcgaattg atcgggaaaa aagtcgtcat tgtagcaaat ctgaaaccac gaaagatgcg
    11161 tggacaaatc agtcaaggaa tgatcctttc tgcagaagca ccagatggct ctttacaagt
    11221 aatcgaagca ccaaaatcca tgccaaatgg ctcagaaatc gcatagaaat tcaaaggggg
    11281 tatgacacta gttgtgtcat accccctttt tccgaaattt gagaagcaat tttcgtaaat
    11341 tccttcttat tacttgaagc caatcatata atacagaaac agagaactat ccaaaataaa
    11401 tcctagaaaa agaagtacga gcttcgctga tttttgttaa tttagaataa tactaatagg
    11461 aatcgtaaaa acagaaaaaa agcataatga taaagggtcg ggcagatttt aattgattca
    11521 tctggtactc ttttttattg tccttacatt cataaagttt gaatgcaatg actttattac
    11581 atctatattt atatctaaca gtagcgttga tgtgttaatt ataagttcta tcactttatg
    11641 ttcaattagt ttgtgctctt atatgtgtga ttgaaaatat agataaaaaa acaatcatcg
    11701 gctttgactt cgatgattgt tttctttatt ttgtaaaaat cctatcactt gattttatgg
    11761 taacctttta tttttgtctt caaacggctt ggtaagagag cagtaagcag tgcaaatggg
    11821 atcgaaaaga cataccagaa aatcgtacgt ccgataccat aatgttgata gagctttgtc
    11881 aacatcacgt gtaacaagat caaccctaaa agcaaggagc cagctataaa ccaatgatta
    11941 tcccaatgca tgacttcact aagtgccatc actccaaaag gatagaaata aaaatagatc
    12001 ccgactaagg tcatccgcca gttctttgta aatgttccga tattcaataa aaagaaaatc
    12061 gctgaaagca aaataccgat aggcggaaaa agcccaacca aaaaggaata caacatcccc
    12121 cacaagatca tcacaggacc tttgatcaat gcaacgattg cgatgaacaa agtcagcaat
    12181 attagttttt gtgataacgt tgcaacagtc attaatccaa ataaaattaa tgtgaaccaa
    12241 tgccaatggg actgctgttg ttctttacgg gaaaaatcga cccggttgga taaataatct
    12301 gctaatttcg gataagaacg cttaaaatcc ataaactgtt cctccttcgt ggaaaaggta
    12361 ggtttagtat acgaaaaata aaaaagaaat acatccgtct taagagggag tttttcactg
    12421 aaagtggaga aaaaagaatg gtaaattaaa atattctcag ttatactgaa aattatacca
    12481 aatttcaaag aagaaagagg atgggaatga aaggcaaact aaaacgagaa atcaatctgt
    12541 ttggcgcatt agctaccgtt atgggaaccg tgatcggtgc aggcgtcttc ttcaaaactg
    12601 ctgctgttac tgctagtact cagtctacaa gtttgacatt gctagcttgg cttttgggtg
    12661 gtttcttaac gatctgtgct ggattgacag tggctgaatt agctacagca atcccggaaa
    12721 ctggtggagc tgtaaaatat attgaagctg cgtatggaaa attgcccagc tttttattag
    12781 gatgggcgca aagcttgatt tactttcctg ctaatattgc tgcattatcg attatctttg
    12841 cgacacaatt gacgaactta ttacaattat ctaccgatta tcttttgttg attgcagtga
    12901 tcaccgctgt ttctgtgaca gggttgaatt tgttagggac aaaagtcggt gcttctgtac
    12961 aatcagtgac gttgattgtt aaattaatac caattgctgt gattgtcata tggggattat
    13021 tgaccccagg acaaggaact gtccagttat ttccaatcga agctggaaaa gatgttactt
    13081 ttgtcgaagg attgagcagt gcgttgttag caacgttgtt tgcttatgac ggctggttag
    13141 gtgtcggtgc aatggcaggg gaaatgaaac ggccggaaaa agatttgcct aaagcaatta
    13201 ttcttggttt gagttttgta acagtcgttt atctattgat caattttgtt tttttgaaaa
    13261 ctttgccgat tgatcatctt gccggtaatt tgaatgcagc ttctgaagca tcagacgtca
    13321 tttttggagg aatcggtgga aagctggtca ctattgggat cttgatctcg gtatacggtg
    13381 cattgaacgg ttatacacta actgggatcc gcgtgcctta tgcgatggct ttagaagacg
    13441 agctaccttt cagtaaacag ctgacaaagc tttcaaagaa gtttacggtt ccttatgttc
    13501 ctgcggtttt ccagttagca gtagcttgta ttatgatgag ccttggttct ttcgactttt
    13561 taacagacat gttgattttt gtgatgtggc tattcagttt actgattttt atcggtgtct
    13621 ttattttaag aaaaaaagcg ccggaattgc cacgtccata taaagtacca ctttatccaa
    13681 tcgttccgat tattgcgatt ctcggtgcta ttttcatttt aggtatgacg atgatgacgc
    13741 aaacgaaatt agcattgatc ggtataggtg ttaccttgat aggtatccca gtctattatc
    13801 aaaaaaagaa aaaacgctca gaagagtaaa atatttcaac aacagacaga aaaagtacga
    13861 actaggtcct ctagatcttc gtgctttttc tatttcaata aaacaagttc ttctattttg
    13921 atttttgcta cttctgcaag tagtgcttat gtgctaaagt aagaatgaaa aggagagata
    13981 aacatgatat ttgattctca tacccattta aatgctgaac agttcaatga agatattcca
    14041 gaaacgattc agcgagcaca agaaatgggg gtaacgaaaa tggcggtcgt gggcttcgat
    14101 acgccaacga ttgaaaagtc tttgcaatta agccatgact atccaaatat atacagtatt
    14161 atcggctggc atccgacaga ggctggcagt tatacgaaag aaatcgaaaa taaattacaa
    14221 gaacaattga ctttaccaaa ggttgtagca ttaggggaaa ttggcttgga ttatcattgg
    14281 atggaagacc cgaaagaagt ccaagataaa gtatttcgca gacagattgc tatcgcaaaa
    14341 gaaatgaacc taccaatcag tattcatact agagaagcac ttgaagacac gtatcaaatc
    14401 ctaaaagaag aagatgttcg agatatcggt ggaatcatgc atagtttcag tggtgattat
    14461 gaatgggcaa aacgatttct tgacttaggg atgcatattt catttagcgg tgtcgtcact
    14521 ttcaaaaaag cattagacgt ccaagaggct gcagcaaatg taccaatcga acgattactt
    14581 gtggaaacag atgcccctta tctggcacca gttcctttta gaggaaagcg aaatgaacca
    14641 ggctatactc gttatacagt agaaaagatt gctgaacttc ggaatcttcc gacagaagaa
    14701 gtggctgccc aaacatggac aaatgcgcac cgattatttg gtctaagcga acatggataa
    14761 gatgaagatc caagagatta tagtcgttga aggaaaagac gatacaagaa ggctgcggga
    14821 agtagttgat gcagatacga tagaaacaat agggtctgca atcaatgaag agatcctgat
    14881 gcaaattgaa catgcccaag agactcgtgg agtgatcgtt tttaccgatc ctgatttttc
    14941 aggagaaaaa ataagaaaaa tcattatgga agctgttcct caggcaaaac atgctttttt
    15001 gccgcgcaca caagctaaac caaagaaaaa gggaagcctt ggtgtcgagc atgcaagtga
    15061 tgctgctatt ttagaagcat tgaaaaaggt cgtgacgcca gacatttccc aaacggctgt
    15121 ttctgaaatc actagacaag accttttaga ctatggttta atagctgggg cacaagcaaa
    15181 agaaaaacga gaaaaactag gtgacgagtt gcgcatcggt tacacgaacg gcaaacaatt
    15241 ggaaaaacgt ttgaagatgt ttcgtattac gccgaaagaa ctcgcccaag caatgaaaat
    15301 agtggaggaa caacatgagt gaatatcgtg aaattgcgac accctctaga acaaaagaga
    15361 ttttattgaa acatggtttt tcatttaaaa aaagtttagg acaaaatttt ctgactgaac
    15421 caaatatttt aaggaaaatc gtagaaactg cgcaaataga tgaacatacg aacgtgatcg
    15481 aagttggacc aggaatcggt gcattgacgg aacaattagc caagcatgca aaacaagtcg
    15541 tagcatttga gatcgatgat cgtttgatcc ctgtattggc tgatacgatg caaccctatg
    15601 acaatgtgac tattgtacat caagatattt taaagaccga tttgtcaaca gctgttagag
    15661 aaacatttca tgaggagctt ccgttaaaag tcgtagcgaa tttaccttac tatattacga
    15721 caccgatcat gatgcatttt cttgaatcag atttggttgt ggatgaacta gtcgtcatga
    15781 tgcaaaaaga agtagctgat cgtatctctg ctgaaccagg aacgaaagct tatggttcat
    15841 tatcgattgc tgttcaatat tatatggaag ccagtttagc attcatcgta ccaaaaacag
    15901 tatttgtccc tcagccaaat gtagattcag cgattttgaa actgacaaga agagatatac
    15961 cggcagtcga agtgacagac gaaaaagcat ttttccgatt gacaaaagcg gcatttcagc
    16021 aaagaagaaa aacgctttgg aataacttgc agcattcgta tggcaaagat gaccagacaa
    16081 aagcatggtt agcaaaaagc ttggaaacag ctggaatcga tccaaaacgt cgtggggaga
    16141 ctttgtcatt acaagaattc gccgcattaa gcaatgcgat gtcagaaaat atgcagtaaa
    16201 aaaagaggtt gtgacagaag ttgtgaaaaa gctgtcctgc atcaagtaat aagaacagcc
    16261 aaacaaaaat agttcctcat gtttttcgtt tgtttgggct tattaccgca gatgcaagct
    16321 tttgaacacc gtttaagaaa gaggttgtgg gcctgccgtt taactctaag tcacaaggaa
    16381 caatttcaaa aaacagcttc tcatgttttt gagttagttg gtcttattac ttgatgcaag
    16441 cttttgacca ctattatgcc gaacaaggag atgtgacaca aattttgtca catctcctat
    16501 ttttgtttct tgatcaaaaa attcttatac ttgatactca cactcatttt gtatggattt
    16561 agaaaagaat atgtgtcttg acagttatta gtaagtgagt tatactaagt cgacatttat
    16621 gtgtcaagac atattaggag agagaaaaaa tgagaaaaaa ttcagttcga aaactaacga
    16681 tttctgcttt attgattggg atgggggtca ttatcccaat ggtcatgcct aaaatcatga
    16741 ttccaccagc ttcctttact ttggcgtctc atgtgccatt atttattgcg atgtttttta
    16801 caccaggagt tgcagtggct gttgcgctag gtacgacatt tggtttcttt ttaacaacgc
    16861 cggttatcat cgcattgcga gcattgtcac atcttgtgtt tgcgttgatt ggggcttggt
    16921 acttgcaaaa gcatccgagt atcgttttaa aaaatggaca gtttactttt gctaattggc
    16981 gtttccaagg gttcaatttt gtgatcggtg tgattcattc tttagcagaa atgctagtag
    17041 tcagcatctt ttactttatt ggtaatatgc ctgaaacata ttattctcaa ggatattttt
    17101 atacagtatt catcttgatg gggattggtg ggcttatcca cagtttagtt gattataata
    17161 ttgcttattt tatagcagga acactcagca aatattttga tatccccgta tttacggcag
    17221 caaaaaaaga aaatcggaaa gagtcgattc aagggtacgc gaagaaaacg acatattaga
    17281 catgatctct caaaaaaaaa actctcatct agtaatggat aataaatcct ctaagatgag
    17341 agttttttgt cctaaaaaga gctgcaccaa catcttctgg cacagctcta acagggggca
    17401 atttatggaa gtttgatgac ttgttctgtt tctttatcaa agaagtggcc tttgctgatg
    17461 ttgaaggcaa ggtcgactat ttcgcctggt ttatggaaat ctcttgcatc tacttttgag
    17521 atgaactcag tagaaccagt ttttgtgtaa agcatcgttt cagctccaag taattcggaa
    17581 acgacaactt ctgatttcac tacggcttca ggtgaagctt caagggctac ttgttcactg
    17641 tggatgtctt ctggacgaat accgaagata acttcttttc cttcataacc tttttcaact
    17701 aatactttgt tttttccttc aggaatacga agcttaagcc catgtccatc tgtgataaca
    17761 ccatttttca atgtcacatt aaagaagttc atggcaggag atccaataaa gccggcaacg
    17821 aacatattga cgggtgtatc ataaacttct ttcggtgtac cgatttgttg gataaatccg
    17881 tctttcatga taacgattcg gtcagccata gtcattgctt ctgtctgatc gtgagtaaca
    17941 tagatggtcg ttgtttcaag acgctggtga agtttggcaa tctcagcacg catggctaca
    18001 cgtaatttag catctaaatt tgataatggc tcatccatta agaagacttt tgcatcccga
    18061 acgattgccc gtcccaatgc cacacgttgg cgttgtccac cagataaagc agctggtttt
    18121 cgtttcaagt attctgtcag acctaagatc tctgctgcat tgtccacacg ttttttgatg
    18181 tctgctttat catatttacg taatttcaag ccaaaagcca tattatcaaa aacagtcata
    18241 tgaggataca atgcgtagtt ttggaaaacc atggcaatat cacggtcttt aggtgccacg
    18301 tcattcatga cttttccgcc gatatttagt tctccttcag agatatcttc cagtcccgcg
    18361 atcattcgca aagtagttga ctttccacaa ccggaaggac caacaaaaac gataaattca
    18421 cggtctttga ttgatagatt aaaatcagtt acagaataat tttctgcatt gtcatatttt
    18481 ttatatacgt ttttcagagc catttctacc ataatacgtt ccacactttc ttttttagtt
    18541 ttattaacta tttaaagtat aaatgaaagc gttaactaac ttcaatgtca tgttgaacaa
    18601 gaattttttc ttttttttgt caatgtgcta gttttaagct ttaataaata tccataagaa
    18661 ataaaaactg atacactgga gtaaataagt atgttaacaa tatcaaaagg agtgtctctt
    18721 atgaaaatcg ctttgatcgc tcatgaccga aaaaaaccta tgatggtgaa attagcaaca
    18781 gcgtataaaa caatattgga aaaacatgaa ctttttgcta ccgggacgac tgggcagagg
    18841 atcacggaag caaccggctt gccgatccat cggtttaaat ccggaccgtt aggcggggat
    18901 cagcaaattg gagccatgat ttcggaggat cagttagatt tggtgatttt tcttcgagac
    18961 ccgctggctg cacagcccca tgaaccagat gtaacagcac ttatccgttt atctgatgtc
    19021 tatgagattc cgttagctac gaatatcgga acagctgagg tgctactaag aggactggaa
    19081 gccggcttcc tagattttcg aagaatcgtc catgaaatag acaagcatcc actttcattt
    19141 tgatggataa gcgtatggaa aaataacgtt taatgttcgc ctatatgtag ctataaaagc
    19201 taaacaaact gataatatgc gatataatac gaacgtattg gataatataa acaataatat
    19261 tagtttttcg tatttgcagt aaatgtgaaa atatgctata gtttctgtgg gaaaagatcc
    19321 caaaaataat acagagtaga aaataaagcg ttaagtgcta agaggatggg atgttgcctc
    19381 ttggacgaag gacgtaatgt tcgcggtttt attttcgcat tcgctgcatg atacgatgta
    19441 gcagctctta aaggagatgc taaaaatgaa gaaacaccgg ttagacgcac gtatgattgc
    19501 tattatgggc ttattgattg cattgatggt cactttgtcc cgactggtag caatcgagac
    19561 cccatttatt aaaatcagtg tcacatttat tccacaagtg atcatgggca ttctttttgg
    19621 tcctttttgg tcagggatag gcgcagtttt agctgattta gtaggaatgg ccctcttctc
    19681 gaaatctgca ttctttattg gatttacatt gaatgcattt attgaaggag caatctacgg
    19741 attctttttc tatcgaaaag agatcacttg gaaaaatgcc attctggcta cgcttagtgt
    19801 cacgctgatc atcaacttat ttttgacacc attatggctt gcgttgatgt accatgtgcc
    19861 attgttcagc tgggtcgttt gggcgccccg cctgttaaaa acagtaatat ggttaccgat
    19921 tcaatcaatt gccatttatt acgtaggacg tagtattcct tacaaaaaaa ttttaagaag
    19981 tttagcgatc cacgctaaat aaaaaacaag cagtcttccc atcccagaag actgcttgtt
    20041 tttattgtgc tgtgaattgt gcttgataga gccgtcggta ataaccatct ttttgaagca
    20101 gctcatcatg ggtgcccatt tcgacaatag ctccctgatc catcactaat atctggtccg
    20161 catttttgat tgtggacagg cgatgggcaa tcacaaaact ggtttttcct tccatcattg
    20221 ctaagaaggc ttgttggatt tttttctctg tcaatgtatc gactgagctg gtagcttcat
    20281 ctaagatcaa cataggggga ttactgatca tcgttcgagc aatcgtcaac agttggcgtt
    20341 gtccatctga tatctttaac ccttgaccgc caatcttagt atctaatttt tccggcaaac
    20401 gttctacaaa ttcatacata taagaggctt ttagggcatc attgatttct gcgtcacttg
    20461 cttccggatt cccaaaacga agattttctc gcaatgtact gtcaaatagc caagtatctt
    20521 gtaacaccat tccaaaactt ttacgtaatg tatcacgttg gatagagcgg atgtcatggt
    20581 catcgactgt aattgttcct tttgttgtgt cataaaaacg catcagcaaa ttaacaagtg
    20641 tggattttcc ggcccctgtt tttcctacta tagcaatggt ttgacctgga taagcagtaa
    20701 aattgaaatc ttcgatcaaa cgctgcttgg ggtcataaga aaaagaaaca tgatcaaaag
    20761 agacttttcc tttgatattt ttgggttcca aggcataggc atctggcaaa tcaggctttt
    20821 cttctggctg atcgatcaaa tcaaatgctc gttctagacc agaaaaagcg gtttgcagtt
    20881 gtgtcgtgat tccagaaagt tcgataaatg gtttagaaaa ctgacttgag tagatcgtaa
    20941 agctggaaat cacaccaaca gtgattgacg aaccactctt caatgccaat aggccgccaa
    21001 ctaaaccaat cgataaataa gcaaggtgat ctacaaaacg agaagacggg tttgtcaagg
    21061 aagaagaaaa ttgtgcccgt tgtccttttt catatagatc agcatttagc agttcaaatt
    21121 gctgttgact agcttcttct tgctgaaaag ctttcacgat tttctggtta ccgattcgtt
    21181 cggtcacaaa gcccgagata tccccaataa tcctttgctg tctatcgaaa tttgtttgtg
    21241 aagcacgagc aacgatccaa ctcacaagga aaataattgg tgtagaacaa agaacgacca
    21301 atgtcagaag tggacttaga cgcatcataa aaataaacga aagaatgatg attgccactc
    21361 cagaaaataa ttgattgaag gccgcagaaa ttgcaatgga aatattgtcc atatcatttg
    21421 taaatcgact gacgatattt ccgtgggagt tttgatcata ataacgaagt ggcaatcgat
    21481 tcagatgagc aaatgcatct tttcttaatt ttgcaacgga taagtaagct aaccgattgc
    21541 ttaacacttg gatgagccat tgactgacta cgttgattaa aacgatacca ccgaatagaa
    21601 taagtaaatg gaacagtcga ttgaagcgga cctgtccttc tccaatcatt tgatcgatac
    21661 tttgaccaat ttgtaacgtc atcacaactg ttgcaatccc attgatgatt cctagtatca
    21721 cagctagcca aatgtctttt gcataggcag taaggtaagg aatgaatcgg cggagcgtct
    21781 gcaaggataa tttttttact ttcataacta ttcttcctcc tgtgatgcga cgatttcctg
    21841 atattctgct gattgagcaa gtaattcttc atgggtaccc tgagcagcaa tcttaccttg
    21901 atccatcact aagatatgat gtgcttcttg aatagagcgg acacgttggg agataataat
    21961 cactgtactg ccaagataag tctgtagcgc cttacgcaaa tccaagtctg tttgataatc
    22021 caacgcactt aaagagtcat ctaaaatcag taatgctggc ttggcaatca aagctcttgc
    22081 aatcgtcagt cgctgttttt gtccgccaga gaaatttttc ccattttcca tgacttttgt
    22141 atctaaacca tttggaagct gacggacaaa ttcttctgcc tgagcgattt tcagagcttc
    22201 ccaacattct ttttctgtgg cgtctttctt accccattga aggttttcac gaatagtccc
    22261 ggtaaatagt acagaagttt ggggaacaag agcaatttgc tgacggagat gatccagctg
    22321 ccaagaacga acatccattc cgtccattat aactgtaccg gaactgacat catagaaacg
    22381 cggaatcaat tgtgtcaaag tcgttttccc gcttccggtt ggaccaatga ttccaaggac
    22441 tgtatttcgc ttcagctgaa atgtaatatt ttggagagaa agaccagaat caggagtata
    22501 acggaagtca acatggtcaa aagcgataat tgcttcagaa gaaaaatcgg gagtagtact
    22561 gacctcagct tcaagaatcg aattttctgt gtctagcacc tctttcaccc gatttcctga
    22621 agcttcggca cgtgtgaaga tcacgacgag gtttgaaaca acgatcagtg ccaaaagcat
    22681 ttgattcata taattgatca aagcaagaac ttgtccttgt tgcaagctac caatatttac
    22741 tttgatcccg ccaactgtca gcaaacagat gatcccgaca ttcatgatca aggttgtagc
    22801 aggtgataat agggcagaga tattggaaac acgtaaataa ttgttcgcta gatcatttgt
    22861 gcttttatcg aacttctctg tttctttttt tgtctgcgca aatgcgcgga tgacacgaac
    22921 accgctaaga ttctgactaa cgtgttcatt gagctgatct agtttttctt gcactttttg
    22981 gtagagagga acggtttttt tgatgataaa aaataaaatg attgagaaaa taggcaataa
    23041 tgctaagaaa aacagaccta cttcccagtc gatcacaaaa gccatgacca ctgacccgat
    23101 acttaaaaac ggtgctctga tcaataaacg aatgaccatt gctaaagcta gctgaagctg
    23161 attgatgtcg tttgtcattc gggtgatcaa ggtatctgtt ccaaaatgat tcaactcgtt
    23221 gtgagagaaa gtattgattt ttttgattag ctgattacgt aactctgtac caaatccttg
    23281 tgaagctact gaagcatagt attggcaaat gatagcacaa atcagaccaa tcacagacat
    23341 agcgaccatc cataagccca tttcaatgat ttttcctcgg tcattcattt ttagtccatt
    23401 atcgatcaag gaagccatca ttaaaggcag gacaagttcg aagacagctt caagaaattt
    23461 gaagaacggg cccaaaatga tttgcttacg atagtctttt gcataacgta ataactgaat
    23521 catatgattc ctcctattat ttatttgtcc acaattgaaa aaacaagtac taccacattg
    23581 tagcttagga aatttagaat gaaaagagaa caagcctttt cataaatgaa agttttatta
    23641 tgaagaagct ttagaaattg aatagactat tttttttaaa aaaaagaaaa tgagaaaaca
    23701 tgccagtctc ttcattcata ggaacgtcta ttttacttaa tttttctata aatgaattct
    23761 gcataaaaaa tatatcaagt aaatgtttat agatgaaact ctatttactt cttttttaat
    23821 ttgttcttgc aatctttttt gctacgtaat ttttgtaaaa aagtgggttg agagaaatct
    23881 aattgatttt caaagaagga gtatgaaaat gagaaaaata tttattcgtt tattgtgggt
    23941 actatcttag aggaataaat aatagtggag aaaactatgg tttggcgcag attctatcag
    24001 gtttgatgga acgaagacaa cctcccgaca tcaagtcaaa agccacttga gattttgatc
    24061 tgaaaataaa aaaagaaaac aaggtaggaa catcaatgtt tctaccttgt tttcgtaatc
    24121 aatgggaaaa aactaagagt ggtgtacgta atcaataaaa aggatggtga caacagtacc
    24181 tctttactct ctgaaagcat cataactcgt ttttcctcat tatgccaata aattgttgtt
    24241 ataccacata taaggatttg taatagctaa aaacagacag gaaagttgaa atctgtgaat
    24301 cttattttgt atggaaggat ttatagaacg caaaaatcaa gataaagatg aataaaaatc
    24361 ctgtttcggc tatatattgc gtatctacgc caataaaacg agtttgttct gtcatagcca
    24421 tataaagcaa aggcaaaaat acaactacag cgagataaga tccgatgatt tctcgaaaag
    24481 ttttccagga agtatgtttc ctgtttttat atttatccga tttcattgaa tagtcatagc
    24541 ctccttattc tttcatatgt tgaaattcca gtataaaaac tggaaggaac tgtacgtttt
    24601 ttagaataaa aattataagg gataagtagg ctgctgtcta taataagata tatttttcaa
    24661 ttctttatta aagattttat tgacaaaatg aatccgtttt ctatgatgga ggaggggtga
    24721 ataagttgtt gaagaaggaa attttatgtt acttagagaa ccagacagcc tttttcgatt
    24781 tagaacatat gaacgaggtc tttacagcac aaaggttagc tgatcatttt ggggtaaaaa
    24841 gaaacacagt cagtcattat ttgaaccagt taaatgatga gcaactacta gtcaaaatca
    24901 attctcgacc agtgatttat ttccacaaag aagcttttga aaaacaattt tttaagttac
    24961 gcacgaattt ttatttttct atcgatgatc tcaaagagga acagcctttt ttcgcgcaac
    25021 caaaagactt attctctttt atgatcggat acgacgccag tttgaaagaa agtatcgaac
    25081 aaatcaaaac agctctttac tatccagatg gcggattacc acttttgatt acaggcgaaa
    25141 gtggcacagg taaaagttat ttagttaatt tggtctatca gtattgtctg cttcatgatc
    25201 tgctagaaga ttctgcacca ttcatcactt ttaattgtgc acaatatgca gataatcctg
    25261 aacttttgac tagcaatttg tttggacatg ttaagggagc gtacactggt gcagaagaaa
    25321 ataaaaaagg ggcttttgaa gcagcagatg gtgggatctt gtttttagac gaggtacatc
    25381 gcttaacacc agaaggtcag gaaaaactgt tcacctatct tgatcaaggt gtgatttatc
    25441 gtatgggaga acctaatttg tcacgccgga tcaaaacacg tctctttttt gctacgactg
    25501 aagagattac tagtcatttc ttaacaactt tcattcgaag aatacctatc cgaatcgaac
    25561 tacctgcact taatcagcgt agtcgtaatg aacggctaga actgatttac tctttttttc
    25621 tcgaagaaca aagaaaaatg gggagccctt tgtcagtcag tggaccagct ttgtcacttt
    25681 taacaagtca gaaattatcc ggaaacatag gagagctgaa aaatatcgtc aaagtttcag
    25741 cagcaaaagc atatgctgaa cagcgtgaac agcctgaaat ccatgtcacg atccatcatt
    25801 tgcaaaaaga actacttgcg cagcctatta ctaaaaatac agcacagcaa ggaatctata
    25861 ttacgcaaga ccagacctta gagcaattaa tggagaagca acagcccgaa cagcagcgaa
    25921 tcgttaaaag ttttgagcaa atcctaattg atttcaagaa aaataactgt ctgctatatt
    25981 cttgcgaagg aaaattaaag caagaagtga ttcaattatt tgattttttg ctgtttgaga
    26041 ccagtagaca agaaaaacac gagctgctgg tttattggac acaatctatc cgagagacct
    26101 ttcgacaaat ggaaactgcc tatcaaatca aattcgatgg aaacagtgtc tatgccttga
    26161 gttactatct ctatcagcga agcactatca aatggttacc ggaagaacat gatattatcc
    26221 aactaatcaa agaattagaa caacaagttt ctcagtctta tccatctagt tatcactatg
    26281 tccaacgaat tctggaatta agtaagatca aattagatat tgaagacaca agtatggatc
    26341 ggattttact gacgatctat ctaaaaaaag cgaaatggtc aaaagaaaaa cgactgccaa
    26401 aagcgatgat tgctgctcac ggttatgcaa ctgctagcag tatggcaaat gtagtaaatc
    26461 gtttattaca agaggatcta tttgaatcat ttgatatgcc actagatgtc acaccacagc
    26521 agattgcttc agaaatcctt gattattgcg aaaacagcga tgtttcaaat ggattgatca
    26581 tattagtaga catgggatct ctgaaagaaa tccatcagtt ttttaaaaaa cagttatccg
    26641 taccgctttt gattttgaat aatgtgacga cacctttagc aatcacagta ggggaatgcc
    26701 tgcaaaaaaa tgtatcatta gaagagatag cagaagagac tgttcgacag atccagccag
    26761 aatggcgact gctctatcca gaggaaaaca aacccaaagc actcattact acttgcttca
    26821 ctggaatcgg tacggcggtc cacttaagtg aactgctaga aaaaagctta cctacggctt
    26881 gtcagttgaa aatcatccca tatgaatatc agcaattaaa agataagaaa aacagtgacc
    26941 cattattttc catatacgaa gtcgtaggaa tgattggcac cacagatcct gatatcacca
    27001 atatcgacta tctttcatta gaagacctca tctcggggga aaagatgtct gtactagctg
    27061 aatggttgga cactactatg aatgcttcag agaaggaaat attcaatcag cgcatcattc
    27121 gtaatttttc attggaaaaa gtactggatt ccgtgactat tctagataca gagaaggtga
    27181 tgggagaaat cgatcatttt atgagagaat tagaggtgca gttgaatcga agcatcagca
    27241 atcccaaaaa attagcgttg tatgtccatg tgagctgtct cattgaacga ttgatccgac
    27301 aaatgccaat cgaaacctat caaggattag agaaatggaa gcagtgtcaa aaagaagggt
    27361 tatctgctat taaatctgcg tttagtgtca ttgaagagca ttatagtgtc atgatcccca
    27421 attctgagat tgcctatatc tatgatattt tgagtgaaga tacagagttt ctctcgatag
    27481 aagaagaatt ttgaacataa gcaagttgtt gccactaatt ttggcatgca acttgctttt
    27541 ttagtatgtg taagtgaaaa gaggagatga aaaagtggat agagaaatta tcttagcttc
    27601 ccatggaaaa tttgcttcag ggatattaga ttcattagag ctgatctatg ggaaaaatca
    27661 ttctattact gtattcgatt gctatactga tgagaatttt gatttagcgg aaacagtaag
    27721 gcagcttttt atgaggtaca aagataaaga aatcattgtt ctgacggatc tttttggcgg
    27781 aagtgtcaac aacgaattct tacaatatat caatcgggat catgtctatc tcgttgccgg
    27841 attgaatttg ccactattga ttgagctagt atctcggttg gacgctgaag tagagacaac
    27901 tgttttgatc cagcaggtgc taactgattc aaaaaaaatg atccagtttt gtaacgagcg
    27961 gctcaatcag aaaatagaag aagacgaatt ttaggaggaa gaaaaatgat tgtattgaca
    28021 agagtcgacc atcggttatt acacggacaa gtagcttttt catggacaca aacaataggc
    28081 gcagactgta ttttgattgc taatgatgat gtacctacga atgagatacg aaagacaacg
    28141 atcaaattag ccaagccaca aggagtcaaa ctagtgatca aatcaattga tgactcgatt
    28201 gccgcgttga aaagcggggt gacagataaa tataagttat tcatcgtagt ggaatcgatc
    28261 gaggatgcat ataagctggc agaagcgtat ccagaaatca aaaccatcaa cttaggaggg
    28321 atcaaggcaa aacctggtac tcgcagcatc ggaaaagcgg taaatatttt accagaagag
    28381 gaggaacgct tgaaacgatt aattgacaaa caaatagaag tagaaatccg tcaagtacca
    28441 gcagataaaa aagtggatgt aagagaagtt ttgtaagaaa ggaagaacct caatgattgt
    28501 acaagcagtc ttattaggaa ttgttgcatt tgtcgcacaa tcagaatatg cactagggac
    28561 atcgttgctt tctcgtccga ttgtgacggg gctgtttaca ggaatcgtgt taggtgatgt
    28621 aaaaactggg atcattatgg gcgcaacttt agagttagca tttatcggat cgttctcagt
    28681 aggtgcttcg attccacctg atgttgtgac cggtgggatt ttagggacgg cttttgctat
    28741 tacagctgga gccggtacag aaaccgcgct tttactaggt ttgccgattg ctacgttgac
    28801 attgatattg aaaaatattt acttagggct tttgattcca attatgaacc ataaagcaga
    28861 caattatgca gaagaaggaa attataaagg agtcgagcat atgcacttgc ttgccggtat
    28921 cggtctttcc ttgatgcttg gtgttgtggt aatggtttct tatatggtgg gaagcaatac
    28981 gatcggaaat ctattaaata tgattcctga cttcgttcaa aaggggttgt cagtagctac
    29041 agggttgatt ccagctcttg gttttgcgat gcttgctcgt ttgctgatca acaaacaagt
    29101 tgcaccatat tttttcttag gttttgctat agcttcttac ttagagattc ctgtgaccgg
    29161 agtagctatt tttggtgcga ttttagcagt tgtggtagtc aatattatga atgtccgtca
    29221 actaccactt caaacaactg caggggaggt agaagaagat gaagaattct gagatcaaaa
    29281 acagcaaaat aacgaaaaaa gagctaaatc acgtattttg gcgttctttt caaatggagt
    29341 tttcttggaa ttatgaacgt cagatgaata tggcttatgt ttatgcaatg attccgattt
    29401 tgaaaaagtt atatcagtcg aaagaagaaa tggcagcagc tttgaaacgg catctagagt
    29461 tttttaacac gaccccacat atcgttacac tgattttagg aatcacggct gcaatggagg
    29521 aagaaaataa ggatgatcct gaatttgatg tgactgcgat cgatagtatc aaaacatctt
    29581 tgatgggacc tcttgcaggg ttaggagatt ctttcttttg gggaactttg cgattgattg
    29641 ccacaggtgt gggtacctct ttagccatgc aaggaaatat tttaggccct atcttgttca
    29701 ttttgatttt caatattccg cacattctgt ttcgctatct agcaacaggt tggggatatc
    29761 gcttaggaac gggttttttg aaaaagatcc aggcaaacgg tatgatggaa agtttgacat
    29821 taggcgcgtc tattattgga ctgatggtcg ttggagcaat gactgccacg atgatcacca
    29881 tcaatattcc tttaaaaatc ggttcaggag aaaatgctgt gactgttcaa agtatttttg
    29941 atgatatcgt tccaaatatc ttatgtcttg gagcatttgg catagtgttt tatctattga
    30001 agaaagaagt gaaaccatta acgatcttga tcggactagc tttctttgga atttttggtt
    30061 cgtggatagg gattttttaa aaaaggagca gagaaaatgt ttacgatgca agattatatc
    30121 tatgaagaaa aggaagtact aagtacgatc ttgaaaaaga atgatttttc gacaagagaa
    30181 catatgaaaa aaacagtgaa tttactgatc ttagcaacgg gttcatctta taacgcttgt
    30241 ttagcagcga agccagcatt ggaatcttat ggtgatctta ctgtcgatat tcaagaacct
    30301 ttttattttt tcaattatgg aaaactttct ccttcaatcg atactgtgat tgctgtgtca
    30361 caaagcggga aaagtgcttc tactgttgaa gcagtaaaaa tgatacaaaa acaagggtta
    30421 cctgttgttg ctatcacaaa tgacgtgcaa agtccacttg ctttagaagc tgcacaaatt
    30481 attgatttag gtgccggggt agaatcagta ggcttcgtta caaaaggcta ttctgcgact
    30541 gttttacagt tactactctt agggatagga attggaataa gtaaaaataa aatcagcaaa
    30601 aaaatagaac aagactacat gcaacagttg cgcaaaataa tcaaccattt accagcgatt
    30661 attcaaaaaa cggaagaatt ttttgatgga tatcaaagtt tatttcgttt agcacagcgt
    30721 ttcgtcacca ttggatatgg tccaaactgg ggaacagcta aagaagcaga gacgaaattg
    30781 actgaaacaa tccgcgttcc gtcacaagga tttgagttag aagcttatat gcacggccca
    30841 tacctggagg cagatgcttc gcatttgcta ttctttattg aaggggaaag tgtaaataag
    30901 gaacgttcgc aaaagttgca aagatatatg agtcggtacg ttggagagac tctcaccatt
    30961 accacaaaaa aagcaagaaa cgagaaaaca cttggattag caatagaatg tgatgaatat
    31021 ctgtctgtat tagcgcttgt cgttccgttt caactattcg cttataaaac cgcagtagct
    31081 aaaggtattg acttgaacaa aaagattttt gaagactttg atacagtctt gaaaagtaaa
    31141 ttataagagg tggaaatcat gctgaaattc aatgaagaag aacaaatcaa agcaataaaa
    31201 ggcgcactag ctttacgtcc gcaagtagaa gaaatcatcg ataaacttta tgcggaaaaa
    31261 tttgacgctg tctattatct aggaatcggt ggaacgtatg cttcctcgat gcaagctgtc
    31321 acttatatga atgggaaaag caacttgcct gtctttgtac agcatgctgc agaatattac
    31381 actactggaa acaaaagatt aacaaaagat tctatcgtta ttttgtcctc tgttaccggt
    31441 acaactcaag aagtagtgaa agcagtagaa caaatcaaga aagtaggagc gacactgatt
    31501 ggatttatcg ataaagcgaa cagtaagttg tctcagctat gcgattttgt ggtcacttat
    31561 ccagctcctg gaacagaaca aatcaaattt tttatggcag cagatcgatt gatgtatttg
    31621 aatggagaat tcgaagctta ttcagaatac tatgaacagc tcgaacgtta tttaccaaca
    31681 gggttagtgg aagcagagaa aaaagcagat gcatttggct tatcatttgc agaaaaacat
    31741 cgacgtgata gtatgcatta ttttattgga gcagggaatc aatggggagc tgtttattca
    31801 tatgccatgt gttactggga agaacaaagc tggcttccat cgaaatctat ccatgctgcc
    31861 gagtttcttc acgggacgtt agagatcgta gaagaaacaa ccccagtcac attattttta
    31921 ggcgaagatg aacagagagt gttatctgaa cgtgtggcta aacttttgcc aaaaatttgc
    31981 agcaattata cattgataga cacaaaagac tatccagtag aaggtatcag tgaaaaatat
    32041 cgcggacgtg ttttgtcttt cttattgatg catgtagtga cacaacgcat cgatgctcat
    32101 gtggagcagt tgaactgcca tccattagag atacgccgct actatcgtca gtttgattat
    32161 taggatagac tggataaaaa gaatataaaa aataaagaga gcagcgataa ctgctccctt
    32221 tattttttta aaatattggc atcaattacg ttataaaaca cattttttgc attatctaca
    32281 gttcaactta taatctgttt aatgggacat gtgggtgcca accatttttt gttatgcaat
    32341 agtactattt agttgttgca tggatccgta gtaaaagtcc aagtacaacg agttgcgcca
    32401 gtttacatag cgttttgtat ccagaatgtt gactaaaaca aaagttccta tgtcaaccgt
    32461 caacagagac aatctgtccg ttgcaggacc tgacagattt agaaatgttc aatctgtctc
    32521 ttatgtattt taaatcaata ctcactagga gaagtttcct aacctcctaa tagtaatgct
    32581 ggtagtaaca ttgtcaaaac tgcttcctct taggaacaag caaagcataa cgagtgtaaa
    32641 aataaaatgt agactattgt aacatatcat tgattatttc aagtaaaaac gataaaagaa
    32701 gtaaacaaac acttaaaaac aatggaaatt agtcccaact ttaagaaatg tatactataa
    32761 tggaaattat caattattta tttggaggaa tatccatgaa acaaaaaatc gcagttcttg
    32821 gtcctggatc ttggggcact gctttagcac aaacattggc agaaaacggg catgatgtcc
    32881 gtatttgggg aaatgtacct gaacagattg atgaaatcaa taagtatcat acaaatcagc
    32941 attttttacc tgatttgacg atcccagaat cgattatcgg atataaagaa ttggcagaag
    33001 cagtggataa cgcagatgct attttatttg ttgttccaac aaaagcgatt cgttcagtcg
    33061 cacaggaact tattggtaaa atgaatacta agccaatcat tatacatgca agtaaaggac
    33121 tagaacaaga tacgcataaa cgaatctcag aagttttggc tgaagaaatt ccagaagaaa
    33181 aaagacaggc aattgttgta ttatctggtc ctagccatgc tgaggaagtg gcagtacatg
    33241 atatcacaac aattacagct gcaagtattg atcaaaaagc agcagcctat gtacaaaaac
    33301 tgttcatgaa tgattatttc aggatttata caaataatga tgtgattggc gtagaaactg
    33361 gtgcagcact gaaaaatatc attgcaattg gtgccggcgc tatccatgga ttaggattcg
    33421 gagatgatgc aaaagcagca atcatgactc gaggattggc agaaatcagc cgtcttggtg
    33481 tcgcgatggg tgccaatcct ctgacattta tcggtttgag tggtgtgggg gacttgatcg
    33541 ttacttgtac aagtgttcat tctcgcaatt ggcgtgccgg taacttgtta ggacagggac
    33601 ataagctgga agaagttcta gaaaacatgg gaatggtcgt tgagggtgtg gcaacgacaa
    33661 aagcagcagt agagctagct caacagctag gtgttgagat gccaattact caaacaatct
    33721 ataatgtttt gtataatgga gaagatatca aaaaagcagc aaaagaaatc atgttacgtg
    33781 acggaaaaat ggagaatgaa ttttctcttc gttaaataga tgatcaatag ttaatcgtcg
    33841 tttaggagga acagcaagtg aaggtcaaaa aagcagtcat tcctgccgct gggctaggaa
    33901 cacgtttttt gccggcaaca aaagccatgg caaaagaaat gcttccaatc gtggataaac
    33961 caacgatcca gtttattgtg gaagaagcat tggattcggg aatcgaagac atcttgatcg
    34021 taacgggaaa agaaaaaaga cccattgaag atcactttga tgcaaatatc gaattggaaa
    34081 acaatttgcg ggaaaaggaa aaaacagaat tactcgcttt agttgaagaa acgactcaag
    34141 tcaatcttca cttcatccgt caatctcatc caagaggact gggggatgcc gtgcttcaag
    34201 caaaagcatt tataggaaat gaaccgtttg tcgtcatgct gggggatgat ttgatgaaag
    34261 atgatatccc attgactcaa caattgatga tggattatga agaaacacaa gcttccgctg
    34321 ttgccgtcat gcgtgtacca gaaaatgaaa catctaaata cggaattatt gatcctaaaa
    34381 cagatagcga aaagggtcgt tgcagagtaa aagggtttgt agaaaaacct gaaatgggaa
    34441 aagcaccaag taatttagcc attatcggac gttatctact gactcctaaa atatttgaga
    34501 tattagaaac tcaagaacca ggagcaggaa acgagataca gctaacggat gcacttcaga
    34561 ctcttaacca gacagaggcg gtctatgcga gagagtttaa aggaaaaaga tacgacgtag
    34621 gcgataagtt aggatatatg aagacaaata ttgaatatgg acttcaacat tcggaaattg
    34681 ggacttcatt aagtgcatat attatccagt tgagtaaaaa gctaagaaca gaaagttaac
    34741 tggaaataag tggcctgctg agaatgaaag gctatttgtt attaaagcgg cagcttgtgc
    34801 gtcatttgcg caactgtcgt tttagttttt tgactctaga tcagttgagt cgtggaaaac
    34861 gaaagataga aaaagacttt cgtgaataga ttcagaaaat attatgctaa tggtttaatt
    34921 tttttttaag ttgtataaaa gaaaatgatt acataagaga aatgaaagcc aagccagaag
    34981 attcatagta gaataaaaag gcgaattttt taattataaa aaaaggtgtg tgttcactat
    35041 gggaaaatta gtcgctgttg cacagtcgct gcttgatata ctcaagtggc tgatggaagg
    35101 aagcaattgg atatttgtgt tgccactatt gcttattagt ctatttatca tgtttcgcat
    35161 ggtcagaaaa aaagaaacgt ttctgatttt tatctggtat gcagcatccg ttggggttgc
    35221 taccttgatg gttgaattgg cgttaggtag ttgggaagct tgcgtatttg ctttattttt
    35281 tgctgtactg tatctaatca tttatatccc atatatgaaa agaaagtctc ggataggcag
    35341 aaaaggtaga catacaacta ctttttctag tacagattct ctcgaacaaa gtagaagaac
    35401 gagaagaaga cggtaatatt tagtaggtat acgcaaaaaa agataaaata atggataaac
    35461 tattgagatg agagatttat ttaattggtg gaaaaaagct tttttcactt atataaaaga
    35521 atctttttta aaggaatgct tgttgtatcg ggataagcca ttcctttttt tatgttattt
    35581 atatatatat aaatcatacc aatgtttttt tgtattttct tgcttgcact tggataagag
    35641 attacttaca ataaattcag atagaaacag ctgaataaaa aaaggctccc tgacccttag
    35701 ttggcgctaa gaatcaggga atgaccagtc acacacatac accctgaccg atcattttgc
    35761 catagtcaat gcagtgcatc gacctaattt attgtaccta atctagggtg aaaattctac
    35821 ccctatgtag atattttcca tggtctgcac gttgttttat ttgctatgtc aaggtattgg
    35881 gcgtattcgt tcaatgcctt ttttgtgttt gaaacagcaa agaccacatg tgttactgtc
    35941 taactactgt ttttttatgt acttccttag attaggcagc tgtttctatt catgtcaagt
    36001 atagctaggc gggagagata aatgagttta tgttattttg actattatca ccaattggaa
    36061 gagaaattaa ggatagaaga gccgctgatg cttcaagctg gcacttggat cgcgaaacaa
    36121 attaatcaag gtggtagatt gcagatatat gctagccgca cactaagtgg tgtagcattt
    36181 gaattttggg atcaaacccc ggatcttgta ccaagtatat tgattgaaaa tccagccgga
    36241 ggtgtctatg aaacgctaga aggtgcagga caggcaatta ttgatcagct ttctgtcaaa
    36301 tcagaagaca tttttcttct tctttcgaat gaaggaagaa acccggcaat catcgaacta
    36361 gctcagtgga tcaaagaaaa tggtcatcca ttaatcattg ttactggatt tgatttgtca
    36421 cgaagtatca aatcgcaaca tagcagtggt ttgcgattat ttgaatttgc tgatttggtt
    36481 ttggacaacc acgccaattt acatgatgca gtcttgactt tgccaaatct agatccagcg
    36541 atctgcggaa cagcctctct tgcaacgatc tttttgctgc agcaagtttt gtattttaca
    36601 gcaaaacagc tagtccagga cacaagtgga aaatagttat ccacatgttg acaaagttcc
    36661 ttaaaaaaat aatgttccac ataaaaatgg agcgtttgaa aaaaagaaaa cgattattaa
    36721 tgaggattaa caacgactac tttttttgtt ttagttattt taagatggat catctttgat
    36781 tttaagcttg ttttgtttaa agtttgttat ttttataagt tgtttcacag ttatgagaaa
    36841 tgagttataa gaatatgtag tgtcagaaaa ataaaaagta gtggaaaaag agacaagaaa
    36901 gaatccatat ggattctttc ttgtctctta atacacgttg atgaaagagt cttccccaaa
    36961 actctttaca aagtaattat agtacatttg ttatcattat tgcaatgaag tttacctgat
    37021 ataacaaaat tgtccaacag gatacctttt tctaatagaa ataaaataca caaaaa
//
LOCUS       DACGEU010000017        36569 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.017, whole genome shotgun sequence.
ACCESSION   DACGEU010000017 DACGEU010000000
VERSION     DACGEU010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36569)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36569)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36569
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.017"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(26..1522)
                     /gene="lysS"
                     /locus_tag="IXR40_000813"
     CDS             complement(26..1522)
                     /gene="lysS"
                     /locus_tag="IXR40_000813"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HAQ4360683.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKTGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(1633..2637)
                     /gene="dusB"
                     /locus_tag="IXR40_000814"
     CDS             complement(1633..2637)
                     /gene="dusB"
                     /locus_tag="IXR40_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HAQ4360684.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVDCREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(2638..3525)
                     /gene="hslO"
                     /locus_tag="IXR40_000815"
     CDS             complement(2638..3525)
                     /gene="hslO"
                     /locus_tag="IXR40_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HAQ4360685.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(3742..5853)
                     /gene="hflB"
                     /locus_tag="IXR40_000816"
     CDS             complement(3742..5853)
                     /gene="hflB"
                     /locus_tag="IXR40_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HAQ4360686.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(5943..6488)
                     /gene="hpt"
                     /locus_tag="IXR40_000817"
     CDS             complement(5943..6488)
                     /gene="hpt"
                     /locus_tag="IXR40_000817"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HAQ4360687.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6488..7933)
                     /gene="tilS"
                     /locus_tag="IXR40_000818"
     CDS             complement(6488..7933)
                     /gene="tilS"
                     /locus_tag="IXR40_000818"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HAQ4360688.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8053..8523)
                     /locus_tag="IXR40_000819"
     CDS             complement(8053..8523)
                     /locus_tag="IXR40_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein S1"
                     /protein_id="HAQ4360689.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(8569..8994)
                     /locus_tag="IXR40_000820"
     CDS             complement(8569..8994)
                     /locus_tag="IXR40_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HAQ4360690.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9061..9330)
                     /locus_tag="IXR40_000821"
     CDS             complement(9061..9330)
                     /locus_tag="IXR40_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HAQ4360691.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9341..10936)
                     /locus_tag="IXR40_000822"
     CDS             complement(9341..10936)
                     /locus_tag="IXR40_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAQ4360692.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(10951..14472)
                     /gene="mfd"
                     /locus_tag="IXR40_000823"
     CDS             complement(10951..14472)
                     /gene="mfd"
                     /locus_tag="IXR40_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HAQ4360693.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14489..15049)
                     /locus_tag="IXR40_000824"
     CDS             complement(14489..15049)
                     /locus_tag="IXR40_000824"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HAQ4360694.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15402..16376
                     /locus_tag="IXR40_000825"
     CDS             15402..16376
                     /locus_tag="IXR40_000825"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HAQ4360695.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            16546..17946
                     /locus_tag="IXR40_000826"
     CDS             16546..17946
                     /locus_tag="IXR40_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase family protein"
                     /protein_id="HAQ4360696.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18024..18746)
                     /locus_tag="IXR40_000827"
     CDS             complement(18024..18746)
                     /locus_tag="IXR40_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAQ4360697.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(18825..19331)
                     /locus_tag="IXR40_000828"
     CDS             complement(18825..19331)
                     /locus_tag="IXR40_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HAQ4360698.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSIDHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19454..21253
                     /locus_tag="IXR40_000829"
     CDS             19454..21253
                     /locus_tag="IXR40_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HAQ4360699.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            complement(21321..22895)
                     /locus_tag="IXR40_000830"
     CDS             complement(21321..22895)
                     /locus_tag="IXR40_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360700.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
     gene            complement(23150..23659)
                     /gene="mreD"
                     /locus_tag="IXR40_000831"
     CDS             complement(23150..23659)
                     /gene="mreD"
                     /locus_tag="IXR40_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HAQ4360701.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            complement(23663..24517)
                     /gene="mreC"
                     /locus_tag="IXR40_000832"
     CDS             complement(23663..24517)
                     /gene="mreC"
                     /locus_tag="IXR40_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HAQ4360702.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            complement(24672..25310)
                     /locus_tag="IXR40_000833"
     CDS             complement(24672..25310)
                     /locus_tag="IXR40_000833"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HAQ4360703.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            complement(25311..25961)
                     /locus_tag="IXR40_000834"
     CDS             complement(25311..25961)
                     /locus_tag="IXR40_000834"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HAQ4360704.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGQFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            complement(25974..26873)
                     /gene="rsgA"
                     /locus_tag="IXR40_000835"
     CDS             complement(25974..26873)
                     /gene="rsgA"
                     /locus_tag="IXR40_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HAQ4360705.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            complement(27038..29107)
                     /gene="pknB"
                     /locus_tag="IXR40_000836"
     CDS             complement(27038..29107)
                     /gene="pknB"
                     /locus_tag="IXR40_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HAQ4360706.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            complement(29104..29844)
                     /locus_tag="IXR40_000837"
     CDS             complement(29104..29844)
                     /locus_tag="IXR40_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HAQ4360707.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            complement(29857..31215)
                     /gene="rsmB"
                     /locus_tag="IXR40_000838"
     CDS             complement(29857..31215)
                     /gene="rsmB"
                     /locus_tag="IXR40_000838"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HAQ4360708.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKTLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            complement(31215..32153)
                     /locus_tag="IXR40_000839"
     CDS             complement(31215..32153)
                     /locus_tag="IXR40_000839"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HAQ4360709.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKEAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            complement(32146..32637)
                     /gene="def"
                     /locus_tag="IXR40_000840"
     CDS             complement(32146..32637)
                     /gene="def"
                     /locus_tag="IXR40_000840"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HAQ4360710.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            complement(32652..35060)
                     /gene="priA"
                     /locus_tag="IXR40_000841"
     CDS             complement(32652..35060)
                     /gene="priA"
                     /locus_tag="IXR40_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HAQ4360711.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            complement(35313..35618)
                     /locus_tag="IXR40_000842"
     CDS             complement(35313..35618)
                     /locus_tag="IXR40_000842"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HAQ4360712.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            complement(35623..36237)
                     /gene="gmk"
                     /locus_tag="IXR40_000843"
     CDS             complement(35623..36237)
                     /gene="gmk"
                     /locus_tag="IXR40_000843"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HAQ4360713.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYINKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEERMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
BASE COUNT         9886 a         7989 c         6705 g        11989 t
ORIGIN      
        1 aattccttag acagctttta ttcgattatc tcattgttgg gaatagcaaa acatcccgaa
       61 ttgattgtgc atcagttagc aacattacta atctgtcgat cccgatgcct agaccaccag
      121 ttggcggcat accgtattct aaggcttcca agaagtcttc gtctacaccg tgagcttcgt
      181 catttcctag ttcacgttct ttttcttgcg cttcgaatct ttctctttga tcaattggat
      241 cgttcagttc tgtaaaggca ttagcaaatt cgcgccccac tatgaatagt tcgaatcgat
      301 ctgtgaatcg aggatcttct ggatttttct tcgctaaagg cgaaacttcg actggatgtc
      361 cgtatacaaa cgtcggttgt gtcaatgttt cttcaacaaa tgtttcaaag aattcattga
      421 taacatgtcc gacacccata gcttcggtta cttctacatt gtgtttttcg gctaaagcta
      481 atgcttcttc caatgtcatt tcttgccaga agtctacacc agtttgttct ttgattgcat
      541 ctaccatatg gatgcgttta aagtcacttt ctaagtcgac agcttgtcca tcatatgtga
      601 tttttgctgt tcctagtact ttttcagctg cgttacggat aataccttct gtcagattca
      661 ttacatcatt gaaatcagta tatgctgtgt atgcttctaa catcgtaaat tctggattat
      721 gtgtagtatc aattccttca ttacggaaaa cgcggccgat ttcataaact ttttccattc
      781 cgccaacaat tagtcgtttt aaatgaagtt ctagcgcaat acgcaaatat aaatcaatgt
      841 ccagtgcatt atgatgcgtg ataaatgggc gtgcggcagc tccacctgcc tcattgtgca
      901 atactggtgt ttctacttca atatagccat tgccatctaa atagcgacgg atttcgctga
      961 taatttggct tcgtttcata aatcggtcaa agctttcgcg attactgatt aaatccaagt
     1021 agcgttgtct gtagcgttgt tcaatattcg ttaagccatg gtatttatct ggcagtggac
     1081 gaagtgcttt tgacaaaatc gtgatttctg aagctttgat agaaacttcg cctgtgtctg
     1141 ttttcatgat ttgtccagtt acaccaaaga aatctccaag gtctgcatgt ttgaatactt
     1201 cataggcctc atcacctact tggtcttttc ttacataaat ttgaatttgg ccttcacgat
     1261 cttgtagatg cgcaaatcca gttttccctt ttcctcggcg agtcatcata cgaccagcta
     1321 cactagcggt caatcccatt tctgctagtt cttcttttgt tcttggatca aatagttcat
     1381 gcaattcttc tgagttgtgc gtgcgttcaa atcgttttcc aaatggatcg attccatctt
     1441 cacgcaattg ttccattttt tgacgacgta caagcatttg atcatttaaa tcttctactt
     1501 gatgttgttg ttcctgtgtc acaaaagttc ctccattctc atgttaatct ctttcctata
     1561 atgccaatga aacacaaaaa aagcaagccg aacttggaat ttcggcttga aaattcacga
     1621 aaaacttaga aatcacaacg tttgtttcaa tagtactttt tccgcttttt ctacaaattg
     1681 atccagcagg tcattgattt cttgctgttt ttctgtctga ttgattgcta ctttcacttt
     1741 cgctgctcga ggaatccctt ttaaataata agccgcatgt gttctgaatt ctctacaatc
     1801 tactttttct cctttgagat ctgctaagcg ttgtaaatga agtttagctg tagcaatttt
     1861 ttcggctggt gttggttcag gaatcagttc tcctgtttcg agataatgct gtgtgcggtg
     1921 aatcatccat ggattgccca gcgctgcacg accaatcatc acaccgtctg caccgacata
     1981 gtcaagcatc cattttgcat cttctggcgt tttgacatcc ccgttcccca taaatgggat
     2041 cgtcaaatgt tttttcactt ctttcaatac ttcccagtcc gcttttcctt catacatctg
     2101 aacccgtgta cgtccatgca tagcgatggc acttgctcca gctgattgtg ctgctaatgc
     2161 attttctaca gcaaagacgt gctcttcatc ccaaccaata cgcatcttga ttgttactgg
     2221 gatatttact gctgaagaaa cagcttggac catttcgtat actttctcag gatctaaaag
     2281 ccattttgct cctgcttctg ctttgattac tttatttact ggacagccca tattgatatc
     2341 tattatatcg gcagctgtgt tttcttcgac aaattgagca gcttcaacta gactatcttt
     2401 atttccgcca aatatctgta aacttaatgg atgttctgtt tcttcaatgt ggagcatctc
     2461 taaagttttt ttgtttctga aatgaatacc ttggtcactg atcatttcac atacgactaa
     2521 gcccgcacca aattctttga cagtgactcg aaatgctgaa tttgttattc cagccatcgg
     2581 tgcaacaacg acacgattag ggatttccac attgccaatt ttccatgtgt gttccactta
     2641 aatccctcct aaggcttctt tcttcaatcc atctaattct tcttcgctat acttgtattt
     2701 gttattacag aaagaacaaa ccgcttctgc accgtgatct tcgtctatca ttgcttggat
     2761 ttcttctgca cctaacgcga taattgcttc tgcaaatttt tcttttgaac agtcacattt
     2821 gaattgaaca ggcatttttt ccaaaatgtt caattcttct gtaccaagca atcctttcaa
     2881 tatttcttct ggtgtctgtc cttcatctaa gagggtagag attcttggtg tcgtttttaa
     2941 ttgttcttcg atcttgctga ttgtttcttc atcggcacct ggcatgattt ggatcatgaa
     3001 tcctcccgcc gtcttgatgc tgtcgtcagt attgaccaat acactcagtc caacagctga
     3061 agggatttgt tctgagatag caagatagta agtaaaatct tcagcgattt ctccagaaac
     3121 aatcggcgtt tgcccagaaa aaggttcttt taatcctaag tcttttgtga cagtaaacat
     3181 tccttgtgtt ccaactgctc cccgcacatc gattttacct tcactattta gaggaagact
     3241 gagatgcgga tttttgatgt aacctttcac atctcccttt ccatttgcat ctactacaat
     3301 tcctgttgct ggaccatcgc cttggattcg aacagttagt ttgtcttctc ctttgagcgt
     3361 cgcaccaagt agcagactac cgaccaatgt ccgtcccaaa gcagctgagg aggtgtgcca
     3421 agtatcatga cgtctttgtg cctccgctac ggtatttgtt gcttgaacgg cgtatgctcg
     3481 gacgaatccg tcgtgagcaa gtgccttaac caaataatct ttcatttgtt atgtactcct
     3541 ttttccgttt ttaaactcat agtgaatcat actagcaact actgcttttt tcaactttgg
     3601 aatgcttctt ttaaaaataa ttcagaatca tctagaaaac aggacatcac cctatttaca
     3661 acttaaataa agaaatctcc cgaaaaccgg tttttgttcc ggttttcggg agtcatatca
     3721 gatcaattga cctatatttt tttatttgta ttgatcgtct gaatgattat cttctgattg
     3781 ttgagaatct gaatcatgtt ctgctttatt ttcctcattc agttcatgtt ttgcttcttc
     3841 aaaatcacgt ttttcttccg cttgtttttc agcgtctttt tcttccaaag cacgttttgc
     3901 ttcttcaaaa gttttcgctt ctttttcgct tggataatca tttgactcag taccttcagg
     3961 catcacaccg tgttcaaaca atgacttgat tgctttggca tccaatgttt cgaattccaa
     4021 aagtttttca gcaatcagtt tatgctgtgc acgatgagct tcgatgattt ctcgagcttt
     4081 atcatgagct tccatcaaga tttttcgtac ttcttgatca atctcgaaag cgacttgttc
     4141 cgagtaagct tttgtttgac catagtcgcg gccaacaaac acttgatggt ttccttcata
     4201 ttgaacagga cctaaacgat cactcattcc atattctgtt accatgcttc gtgctagagc
     4261 tgtcgcttgc tcaaagtcat tggaagcacc agttgattgg acattgaaga tgatttcttc
     4321 agctgtacgt ccaccaagta agcctacgat ttgttcaaac atatcttctt tcgtcatcaa
     4381 gaactgatct tcttttggta aagcgatcat atatccgccg gcgcgtccgc gagggatgat
     4441 cgttactttg tggacgaccc gagcgcgact caatactaat ccgacaatcg tatgaccagc
     4501 ttcgtgataa gcaaccattt cgcgttcttt tttgctgatt acgcgatctt ttttagctgg
     4561 acctgcaatc acgcgatctt ccgcttcatc gatatcagaa gcatcgattt tctttttatt
     4621 tcttctagca gctactaacg ctgcttcatt caagacattt tctaaatctg ctccggcaaa
     4681 acctggtgtc tgttgagcca caactttcaa gtcaacgtca tctgccatcg gtttattccg
     4741 tgcatggact cgcaagattg cttcacgacc ttttacatct ggacgtccaa ctaaaatctg
     4801 gcggtcaaaa cggcctggac gtagtaacgc tgggtctagt acatcagaac ggttggttgc
     4861 agcaatgacg attactcctt catttccgtc gaagccatcc atttctacaa gcaattggtt
     4921 caatgtttgt tcgcgttcat catgtccgcc gcccataccg gcaccacgtt gacgacctac
     4981 cgcatcaatt tcatcaatga aaatgatagc tggtgcgttt ttcttcgctg tttcaaacaa
     5041 atcacgaaca cgacttgctc caacaccgac aaacatttct acgaaatcag aacccgagat
     5101 cgagtaaaac ggtactccag cttctccggc aacagctttt gctaataagg ttttacctgt
     5161 tcctggaggt ccttctaaaa gtacacctgc cgggatacgg gcacctaatt caacaaatcg
     5221 gcgaggatct ttcagaaatt caacaacttc aactagttct tgtttttctt cttccgcacc
     5281 cgctacatca gaaaaacgta cgcgattagc ttttttgtct gcttctttgg cttttgattt
     5341 accaaagttc atgacacggc cgccaccgcc accgccgccg ccttgttgtc ccatcatcat
     5401 gtaaaagaaa aagatgatga ttacgattgg caagaagcta agcaataggg aaacccatat
     5461 accgctgctt gattcttctt ttactgttgt agcaactttg ttttcttttg ccagttctgt
     5521 tacttggctc aatgttgtat catttggcaa aatgattgtt gtgaaatggg tagtagtcgt
     5581 atctgttgaa cctaagatag ctaacccacc gctgttagcg acggtctgct gttctttgta
     5641 ttcaccagtg atcttatata caccatttgc aggctgcact tcaaattctt tgatcttgcc
     5701 tgcttgtagt tgttctgtga attttgagta ctcgatatct gacgatcgct ggccgttatt
     5761 accaaaaatg aaataaacga ccattaccat cgctaagatt acgaggacat aatacaaggc
     5821 atttttcatc atgccgttgt tctttttgtt catagttgcc ctccctaagc gtcaatttaa
     5881 tttaacagtt ttttatcaat cctgaccatt ctattgtacc ataatttaat tgagatacag
     5941 cattaatttg attgataaac actaggtttc aatacaccga tgtacggaag gttacgatat
     6001 gcttctgcat aatccaagcc ataaccgacc acaaattcat ttggtacgtt gaagccaaca
     6061 taatctgctt cgatatttac tactcttcct tcaggtttgt caagtagtgt aacaattttg
     6121 actgattttg ctttgcggta tttgaaaaga tccactaaat aagcaagtgt tcttccgctg
     6181 tcaatgatat cttcaacgat caacagatcg cgaccttcta cattcgtatc taagtctttg
     6241 acgattttta cttcccctga cgagactgtt gcattcccgt agcttgaaac atccatgaaa
     6301 tccaattcca aatacgtatc gatagaacga acgatatctg ccatgaatgg taccgctcct
     6361 tttaagacac ctactactag gggattggtg ttttggtaaa tttctgttaa ctctttgcct
     6421 agttctttgc aacgaacttg tatctcttct tgtgagatca aaattctctc aatatccttt
     6481 tccaacatca ggttctcctt ccaattgctt ctttttgata tttgtaaaga agtatgtagt
     6541 gtattttatc agtttcttca cgaatactca aatatgaaaa ggcaaaaggt atcaagctat
     6601 atatatttct tttggcatct gtaatgatcc aagcatgctg cctttgtgaa ttaggtactt
     6661 tctgatcgat aaaatatcta gatacttttt ttgtgagatt ctctgttaat ttaatgcggt
     6721 ctcctgcttt tcttttttcg acatacagtt gcacatcagc aggaatccaa atgtcatgag
     6781 aaaatagaga ccatgaatct gttgctttga tgtcccctgc attttcaggt ttgaccagac
     6841 caatccattc tgtttcattc aaatatattc cttgttctgg aatcagcaac aagcgctggt
     6901 cttctgtctg gctagttgct tgtttttctt ttttagagag tacaacaaaa tgatactctc
     6961 ttttcagtat ccaattattg ccaatactga gttgccattg gctttttttc tgttgccact
     7021 ggtctaaaat cgactccatt tgttgttctt tcaaaataat tcctgttttt gagaatgctt
     7081 tgtcgaaaaa ggagtaaaaa aaatagtatc gttcagcatc tgtcatttct tcaatcattt
     7141 ctgcagaaaa tcgaaattgt tcctcccact gttcgacttc cttttcgatc aactgtccca
     7201 tatatttttg aatgacttgg tctgcccatt ggatctgttg cgaaaattgc tggaaatgtc
     7261 tcaacgcctg tgtattttct tgtttcaatt gaggaactac caaatgacga agccgatttc
     7321 tctggatatc taacaattgg tttgtctgat cctcaaagta aacaagctgc gattccgctg
     7381 cataagtata taggtcttct ttgctaaaac tcagcaacgg acgaatcagt ctgcccgtag
     7441 caaatggttg tacttctttg attccagaaa aagtatttaa ctgtccccca cgaacgattt
     7501 tcattaacac cgtctcgatt tgatcatctc cgtgatgagc agtcatcaac gtgtcatatt
     7561 gtccttcttc catcacgcga gtgaattctt gataacgaaa gttacgagct tctgtttcta
     7621 tggcggattt ggctggatct tcccaaatac ttacatataa agggagattc ttctcttcac
     7681 aatatgagcg aagataggca gcttcttctg ctgattcttc tcttaattgg tgattgatgt
     7741 ggacgatacc taaagaaaaa ccgatttggc gttgcacttg taaaagtaaa tggagcaaaa
     7801 ccatcgaatc aacaccacct gataccgctg ctaaaattct cgatccttgt tgccagaatc
     7861 cttgttcatt cccgtgccga ataaatgact gctgtaatag cggtgctttt ttcccgcctt
     7921 tttcaacgtt catcctttcc acaccctttc ttcctaaaaa aaagagagcg ggaaaacgtc
     7981 taaaacgaca attaacctgc cctctgttga tactatgacc caaatagtcg cactatcatt
     8041 atttgcggct ttttagctgc gacgtccgcc acggccaccg cgctttcctt ctgtgtttcg
     8101 cttcaatgaa gataagcggt catcgctatc tttcaaaaat gaactcatca atgaatcgaa
     8161 gtcttctttt tgagctgaag gttgactgcg agaaaaagat tttttctgtg ctggacgatt
     8221 tcggttgtca cggggatctt tttgttgata ttttttagga cggctttctt ctccagattc
     8281 agcaggttgt tcctgcgctt tccggataga tagtccgatt tttccatcat catttactga
     8341 aataacttta actgttactt catctcctac acttaaaaca tcatggatgt cttttacata
     8401 gccatttgac acttcgctaa tatgaactag acccgttttt ccagcaccta gatcaataaa
     8461 cgcaccaaaa tttgtgattc ctgatacttt tccttgcagt tttgctccta cctcgattga
     8521 cataaaaaaa atgttcctcc taattatttc ccttttttat attcctgctt attttgcagt
     8581 tgtagaacta gttgattgat ctgtttcatt tgtcgagctg tctgtatttg attctaatat
     8641 aggataaact ttttcaccgt cttttgagta aaagaatttg cttctggcaa gtttagctac
     8701 atactcatca tctttcagca atgaaacatc ttggtgcagc tgatcaacgt ctgcgttgac
     8761 ttctttcatt tcagtatttg cttcgactct caattcgttc aattgatgca tcctttgcat
     8821 gtcatggaaa atctgcacac ctattatcgc gaaaatgacc aaagcaccaa caaaaattgc
     8881 agccagtctg cgtcttcgaa aaatcagttg acgttgttgt tgctgaaatt cagcatactt
     8941 tttctttgca tattccgtat ctagcgcagc gattttattg ctttttttcg tcacttggat
     9001 tcgctccaat ctttttgatt gtctttttca ttataccaat atcgtgaaag cttgtctaat
     9061 ctatttctct agtgtttctg tgcgattttc agaaataatt tcgtacattt tttgtgcatc
     9121 ttcttttttg gttgattcat gtaattccgt aattttcact tccaacgttt tgttgccaaa
     9181 ctggactttc aaaatatcgc ctactttgac atcactggaa gatttcgcca atttaccgtt
     9241 gatttgaatt cttcctttat cagctacttc ttttgctact gatcgtcttt tgatgattcg
     9301 ggaaattttt aaaaatttat ctaatcgcat atcttattcc tcacttttta atttttttat
     9361 ttaatcgcag gattttctta ccaaaaggca acattagcca ttctcgtact gtaaacagac
     9421 gaagacgaat cactgcataa atgaacacag aagccccgat cccaactcct atcacgctga
     9481 caaaaaaagc agtggaacga tgagttacag gaccaaatac tatattcaat acaccataat
     9541 acagcagcag tactactgtc atacaaagaa ggctgaacat caacttccgt ccaaaatgcc
     9601 gttctttcca aaaagcattt agctcttttg tttcaattcg aacaaaatac caaagcgtca
     9661 cacctaatcc taaaagggta gacaggcttg cacctgctgt tcctaataaa ccggtcagaa
     9721 aagaagtagt caatcctttt accaatagtc cccatcctgc gccttttaaa gaagggcgaa
     9781 acgagttctt gctttgagca atactttgat aagcttggat gactgcagtg aaagcaatgg
     9841 aaaaaacaaa taatacaagc gctgcatttc ccgcataatc tttaaacaac gcataattga
     9901 tataagggag cagcaaggct aatcccaaag acgcagctaa tgctaaagcg gtcgtcaatc
     9961 taagatagat tttggctgtc tgtaaaaact gacgatagat ccggttggtc aaatgacgag
    10021 tcaacgcagg caggaatgtc gcacttaatg cagtggcaat cactaaacct aattgtacta
    10081 aaggctgacc tcgatcatag accccttttg ctatcttcgc accgtattct gacagtccgt
    10141 aaacttccaa agcatttttt acaaagaaag agtcgatcag ctggaaaaag ataagcaatc
    10201 cactataaat cgaaaccagt ccgccttcta ccagaaaacg ccggatcaag ggctttgacg
    10261 gctgtttgaa caatggaaac cgtcggaagc ttaacgctcc tccatgaatc ttttgttcat
    10321 agtagtgaag gatcccatat gcgcataaac cgccaaaaac agctccactc attgctgccg
    10381 tccctgtttg gtacaccgtc catccaagct ttctaaaagc aaacgcacta cagacaatca
    10441 caaaaacacg aacgaactgc tcaactactt gagaaacagc agttggttcc atcaagaatc
    10501 ttccttggaa attccctcga taaaaagata gaccaggcat cagcaaaaag gtaaaggaaa
    10561 ctacttggat cagcggtttc aattgtatgt ctcccatcat ccaagcaatc cagctgctaa
    10621 atgcaaagac aaacaaccac aaaaagacac ctgtccaaaa tactaaggga taaagatttt
    10681 gcaaagcttg ctttcgctcg aaaggattct ttctttctgc aacgtacttt gatatgaact
    10741 gcggaagacc ggataaagct aaagtcattg ctatcccata aattggataa acttgctgat
    10801 aaacataaaa accttcgtcg ccgactaagt tttggagggg aattcggtaa agggcactta
    10861 atacttttgc tatgaaagaa gcaatcgtca atacaaatgc tccttgcatg acgcgccgca
    10921 tttctttatg atccaaatca ttgctccttc ctacgctgac agatattttt gctcacgcaa
    10981 cgctttgaca aacttttgga tttcctgaag ccatactgct tcttccattt ggttggggat
    11041 cgtcaagcgt atcaccatct gttctttttc aacgcctaga ctggctttta gttttgtcgc
    11101 tgtcagtgct tcgaataact gttccacact atagcgtttt gttccaactt tacttagagt
    11161 aaagactata tgcgcctcct gtttccttat cgtttctagg agcgctcgat cgccatccat
    11221 tttgatctgc ccaattgtca agagatgtgc tacttcttct ggatattctc caaaacggtc
    11281 gagcagatca tcttctagtt catctagcat ttcttgcgaa tcaagttcac gaattcgttt
    11341 atagatctcg attttctgcc gttgatctgc cacgtatgtt tcaggtagat acgcatcgac
    11401 accgaggtcg atctcaacag tggtcttctc cacttgacta ttctttcctt gtttacgaga
    11461 aacagcttcg cttagcattt gagaatacat atcgaaaccg actgcatcaa taaatccatg
    11521 ctgctgagca cctaagagat tacctgcacc gcgaatggaa agatcccgca tcgcaatctt
    11581 gaatccagat cccagttctg taaaatcttt gattgcctga agacgttttt cactgacttc
    11641 gttaaggatc ttctgctgct catacataaa gtaagcatat gcgacacggc tgcttcttcc
    11701 tacccgccct cgcaattggt ataacgtgga taatcccata taatcagcgt tctcaacgaa
    11761 caacgtattt gcgttcggga tatctactcc tgtttcaatg atggttgtag tgacaagaac
    11821 atcatattga ccttcaataa attcaaaaag cgtattttct aattgcgcct ctgtcatttg
    11881 cccatgagca taaccgatcc gtgcttccgg aacgagttct tggatttctt ctactttttg
    11941 ttcgatcgtt tctacccgat tatataaata gaatacttgt ccacctcgtc ccatttctcg
    12001 atggattgct tcgcgaatag ccccaggatt tttttccata acatacgttt ggatcggata
    12061 acgattcgca ggcggtgttt cgattactga aagatcccgc acgcctaaca tcgacatatg
    12121 caaagttctc ggaatcggtg ttgcagtcag agtcaaaaca tccacttgtg cacgtaactg
    12181 tttcaatcgt tccttatgtt ttacaccaaa acgttgttct tcgtcaatga tcagtagacc
    12241 caaatcgcta aattcaatat cttttgacaa aattcggtgg gttcctacaa caatatcaac
    12301 ttgacctgta cgcagttgtt cgatggtttc tttttgttgc tttcttgttc tgaaacgact
    12361 taatagcccg atatttacgg ggaaaccttc aaatctttcc agcatcgttt catagtgctg
    12421 ctgtgccaag atcgttgttg gaactaaaaa ggctacttgt ttgctttcct ttatcgcttt
    12481 aaaggccgct cgaagcgcta cttctgtttt cccataacca acatcaccta cgagtagtcg
    12541 atccattggt ttttcttttt ccatatcccg tttgatctcc gctgcacttc tcaactggtc
    12601 atcagtttca gagtagggga aggcattttc gaattctttt tggtaggcgt catcaggtcc
    12661 aaaagcatat cctttttctg actctcttgc ggcatataat ttgattagat cgtcagcgat
    12721 atcctcgatt tttgaagaga cttttcgctt ggttttcgtc cattcacttc cgcctagctt
    12781 attgatgcga ggcgctttgg cttcagaggc gacatatttt tggatcagat tcagttgagt
    12841 aacaggaata aacagtttgt cgtcgttttg atacaaaata gtcatatagt cttggtgaac
    12901 gccatctact tctagcgttt ccatcccaat gtatttcccg ataccatgat tggcatggac
    12961 aacgtaatct cctgctttta actcattata gcttttcaat cgctctgcgt ttgttactgt
    13021 ttgacgtctc gtttgttttt tcgtcgtttt ttggaaaatt tctttttctg tgatagctac
    13081 tattttttct tgaggaagtt caaaaccagc ctgcaaagct ccttcaacta attgtacctg
    13141 tcctctgatc aatgcatttt tttctgtttc tactactaat atgtcttcat ctcgaagcat
    13201 ttgttctgct ttgcgtattc tgtcctttgt cggaataaag atcacaacag tctgtttttg
    13261 cttgcgccaa cggtccattt ctgttttcag caatggcatt tgtccgaaga actgttgcat
    13321 cgtccgatat tgaaaattat ggattgcttg gaaacgaaga tttcccatcc ctttttggaa
    13381 gagtgagaaa aaggttgtgg tgaacttttc cttctgcacg attttttgta tatctgctga
    13441 aaatgtctgc tcagaaaaca cccgcaattc gctgattttt tgagtctgcc attctgccgc
    13501 ttccctttcg atttcccgat ttgtttccat gattcgctga taatcatcaa cgactagtaa
    13561 actatttgaa gggaaataat ccaagatcgt cacagattct tggtaaagaa gatctgagta
    13621 gaattttgct tcttctgtcg ggacacctgc ttgccagctt gaagtcagct gaccgaagta
    13681 atcttgcaaa aactcgcggt ctgcttcttc tgtggtcgca gcaagccgtt tttctagcat
    13741 tttttgcatt tgctctattc catgttctag atcctctggt ccgtagactt gttcactcgt
    13801 tggggaaacc cagatttctt ccgttttttc gattgagcgt tgtgtttctg cttcaaaata
    13861 ccgcatagaa tctatctcta catcaaatag ttctacacga acaggatagg ttgtcgttaa
    13921 cgggtaaata tcgataatgc ttcctcgaat actgaattct cccggttttg cgaccatctc
    13981 ttctcgtaca tagcccatca aagtcaattg gcgaggaaga ttttccacgt ctatctcatc
    14041 accaatatgc caattcaatt gcgcctgtag ccaagttttc ttattcggca gtcgtttgtg
    14101 caaagatgcg actggcaaca aatagatacc tgcttttttt tcttgaagtg cgttaagcgt
    14161 tgcaactctc tcgcctcgcg cttctggaga agaaaaggcc atttcagcag aaagcacttc
    14221 atccactgga aataaatgga tctgatcttg cggaatcaca tgttgcagat cttctgctaa
    14281 ctgattcgca taatacaaat ttggcatcag aataatcatg tttttatttg ttttcttaaa
    14341 cgctcgagca aatagaagtg ttttcgctga gcccgctaat cctgtgatta gttgtctagg
    14401 cattttttct tctaaattgc tgacccattc ttttacttgc ggatcttttc cgactaattg
    14461 aataatatcc attccttttc ctccttcctc aattgaatcg attcatcgca tccacgaacg
    14521 aatgcccttc tatgagatat tcgactgctt taacagattg acacatgctt tcttctatca
    14581 aaggctgatt ttctttgctg aaaggactaa gcacatgctg gactactgtt tttttccctt
    14641 ctggcctgcc gattcccacc ttgattcgat caaagacatt cgtattcaaa tgggaaataa
    14701 tacttttgat accgttatgc ccgccggcac ttcccttttg acggagccgg atttttccca
    14761 ctgccagatc caaatcatcg tagattacga ctaattcctc tggataaatc ccaaaataag
    14821 tcattagtgg gccgactgca cgaccagatt cattcatgaa tgtttgtggt ttgactaaaa
    14881 ggatcttttc tccattatga aaaaattcgg caacttctgc ttcgaacgga ttttttttga
    14941 aagtagcttg atgctcgcgt gcaattttat ccacgaccat aaagccgata ttgtgttttg
    15001 tatattggta tttggtacct gggtttccta acccgacgat cattttcatt tttgttttcc
    15061 acctaattct aaaaagcagc acaaaaggct ggactgctaa ttagcggtcc agtccatcga
    15121 gcttttttct tttttatact tgtcaatgca tagtataaca caaaacaagg cgtttcggct
    15181 aaaagagaat cgttaataaa tgataaagaa attaaaaatt tcttcaaagt ttaatgaaat
    15241 aattgatata taaaaatagt gaaataacgc acatgtaagc ttttacatat aatacaacct
    15301 tgttatctgt tatattttat agccaaatag cgtgacatgg ggcttgagaa atgttagcat
    15361 aagcatggga aaaaacaaat caatggaagg attgatacta aatgactgca gctgcagaaa
    15421 aaaaagatca tcaaaaagtt attcttgttg gagacggcgc cgtaggttct agctatgcct
    15481 ttgctctagt tactcaaaat atcgctcaag aagtaggtat tgtggatatc aatactgcta
    15541 aaactgaagg agacgcaatt gacttgtctc acgctttggc atttacttca cctaaaaaaa
    15601 tctattctgc tacttacgca gacgcacatg atgctgactt agttgttatt acagctggcg
    15661 caccacaaaa accaggtgaa actcgtttag acttagtaaa caaaaaccta aaaatcaacc
    15721 gcgatgttgt cacacaaatc gttgaatcag gatttaacgg tatcttttta gttgccgcta
    15781 acccagtaga tattttgact tactcaactt ggaaattctc aggtttccct aaagaacgcg
    15841 taatcggttc aggtacctct cttgactcag ctcgtttccg tcaagcactt gcggaattag
    15901 ttgacgttga tgcacgtaac gtccatgctt acatcttagg tgaacacgga gattcagaat
    15961 tcccagtttg gtcacatgca aatgttgccg gcttgcaaat ctatgaatgg gtaaaaaaca
    16021 acccagaaat cgatgaagaa gctatggtta acctattctt tggcgtacgt gacgctgctt
    16081 acacaattat cgagaaaaaa ggcgctactt tctatggtat cgcagtagca ttagcacgta
    16141 tcactcgtgc catcttagat gatgaaaatg ctgttcttcc tttatcagta ttcatgaatg
    16201 gcgaatatgg attgaacgac atctacattg gtgcacctgc tgttatcaac cgtcaaggta
    16261 tccaaaaagt aatcgaaatt cctttaagtg acagcgagca agaccgtatg gctgcttctg
    16321 ctaagcaatt aaaagaaatt ctagatgaag cttttgctaa actagacgct gaataatctt
    16381 tgaacatgac ggaaaacatc tattcggtgt tttccgtttt tttattttat cacccttatg
    16441 gtttctaaat tttttcataa agtagagata accttcgtct tttcctctaa attatgctat
    16501 catgagaccg ttccacccta aacttttact taaggagttg tcgatatgac aagatcttcg
    16561 catcgaaaaa aatcgaaaca tgttgctttg ctttcagttc ttggtgttct cttagtgctg
    16621 atcagctttt atacctatcg cagtacatac tacacaaagc attttttgcc gaatacagaa
    16681 ataaatggaa taaatgtcag caatctaaca gtcgaaaaag caaatgaaaa attaaaagaa
    16741 gcttattctg ataaaaaact ggctattaaa gaagatggaa aagtctggca ggaagtacca
    16801 aaatccgagc tcggctacaa agatgatttc acttcggagc tttctccgat cctaaatgaa
    16861 caaaacggat ggacttgggg aatgacttat gtctcagcgg cagaaaaaca agaaatagat
    16921 cctgtcagtc aaaaccacca aaaactagac actaccgttc agacattgac aactaagctg
    16981 actgatttga acaaagaccg gacacctact actgatgcaa cgatcgaaaa agcaggtgac
    17041 tctttcgtta tcaagcctga agtcaatgga aatacgatcg acgtcgatgc tgcggtcaaa
    17101 caattaaaaa gtgcggtaaa ctctggtaaa gatacaattg aattgactga attcaaagaa
    17161 aaaccaaaag taacatctga agacagctca ctgaaagaac aactcgcatc catgaatgct
    17221 atcgcaaatg taaaagctac ttacagtata aacggtgaga ctttccagat cccatcaagt
    17281 gatattatga gttggctgac ctacaatgat ggaaaagtcg atttagatac agaacaagta
    17341 cgtcaatatg taacagattt aggcacaaag tataacacaa gtacgaatga cacaaaattt
    17401 aaaagtacaa aaagaggaga agttacggtc ccagttggca cttacagttg gacgatccaa
    17461 acagacagtg agacagaagc attgaaaaaa gcgattctgg caggccaaga ttttactcgt
    17521 tcacccattg tgcaaggtgg cacaaccgct gatcatccat tgatcgaaga tacgtatatc
    17581 gaagttgatc tggagaacca gcatatgtgg tattacaaag acggaaaagt ggcccttgaa
    17641 acagatatcg tttccggaaa gccaactaca cctacacctg ctggagtctt ctatgtttgg
    17701 aataaagaag aagatgcaac tttaaaagga acaaatgacg atggaacacc ttacgagagt
    17761 ccggtaaact actggatgcc gattgactgg acaggtgttg gtatccacga ttcagactgg
    17821 caacctgaat acggtggaga cttatggaaa acccgcggtt cacacggctg catcaacacc
    17881 ccaccaagtg taatgaagga attattcggg atggtcgaaa aaggaacgcc tgtattggtc
    17941 ttctaacaaa aataatatat aaaaagaaag cacccgtacg attggtacag gtgctttctt
    18001 tttattatct aacaatgtgc tacttacatt tcagcagcag taaagacttc tgaaacatca
    18061 tcatcgtctt ctagcttatc tactagacgt tccaattgct ctttttgttc ctcatttaaa
    18121 tcaatcgtcg tttgtggaat catcgtcaat tctgcttgcg ccaaagtgaa ctctttttcc
    18181 aactcatctc gtacagcagc aaaatcttct ggtgcagtat aaatctcgaa tacttcagga
    18241 gaagtttgca gatcttctgc ccccgcctct aatacatcct caaacatcgt ctcttcatca
    18301 acagtcaacc catcgcgttc aatagcgata tatcctttgc ggtcaaacaa gtaactgact
    18361 gaacccgttt ctcccagtga tccaccgttt cgagtaaaag ctactcggac atttgtcgct
    18421 gtccgattac ggttatctgt caatgcatgg actaagattc ctactccacc cggaccatat
    18481 ccttcatacg tgatttcatc gtaattcgtt tcatctacgg cactcgtagc ctttttaatc
    18541 gcccgttcca cattgtcgtt aggcatattt gcagcttttg ctttgtccac aacaagccgc
    18601 aaagctggat tcatagatgg atcaggaccg cctgctttag ctgccatata aatttcacga
    18661 gaaagtttct gaaagacttt ccctcgtttt gcatcttggg cattttttct tccttggata
    18721 ttatgccatt tactatgtcc tgacatgatt tttcctccct tgttcttttg agaatacact
    18781 tctattctag tactatttca caaaaaaaca aagccacagc caatctataa acgcttcttg
    18841 aatgccgcaa aaagcacaca taatatcaca gcagtcagag caccgatcga atccaacatg
    18901 acatcttgga acataggtgt tcgtccaccg gtcatcatct gatggaattc gtccaaacct
    18961 gcgtaccctg ttgctgaaag ccaagcaagg atcgctgtca gccaccaaat ttttagcttg
    19021 gggaaaacac ctaaaaacaa gctgcctccc aaaataaaat aggtaccgaa atgtgcgccc
    19081 ttccttaaaa agaactctaa aaatttggcg tagcccagat ggtcgatact caccatactt
    19141 ccaccataat taaaacgtat acccgctaat gtgtctttaa atggctgatt aggcagccag
    19201 ctttctaatc gcgaaacttg tgattgctgt ccgtaagttt gagaagaact gtaaaataag
    19261 attataacga ctatcagtgc gattactaaa taaatatttc cgtttttcat ttgttttttt
    19321 gaagaattca taagtcacct ctgtatttta tcttagactt tttttgaaga aacaacaatc
    19381 attttcatag agacttcttc cataaaaaag tgctatactt aattttgtat tacaatatga
    19441 agggagtttt ttcatgagtt attcattaaa ttggaatcta gattctattt tttccggagg
    19501 cagtcattct gatgctttga accaacggat gaagcaattg gaagaccaaa tgaacgagta
    19561 ttatcaccgc gtaacaaaat ggtcacctag ttctgacaat gcagagcagt taaacgctat
    19621 tcttcaattg caagaaacga ttacgaatgg ttttacccaa tgcagcagct atattactgc
    19681 attgctttct gccaatgtca atgattcaga tgcaaaggtc ttatcaggca agctttacgc
    19741 aatgctgcct cgtctgcaat cagccgaaac tgtattgtca aagaaatttg cagaaatatc
    19801 tgacaatgat tggaatcaga tgctttctca atcttcgttt gaaacaattg cttttcgttt
    19861 aaacgagatt cgtcgtgatg gctcacaatt attatcagaa gctgaagaaa acattataaa
    19921 tacgctttct ttagatggtc taaatgcttg gagcagtcat tatgatacga ttgtagccag
    19981 catttcgatt cccttcgaac aagatggaca agtagtcgaa ttatctgctg gacaagcctt
    20041 caataagatg atgggcgatc cagatccaaa agtcagagaa acacttttcg cagcatggga
    20101 agaagcctgg aaagaaaagg cacccctctt cacggatact ttgaatcatt tagatggttt
    20161 tagactttct gactatgaac ttcatggtgt cacagatttt ctacaaaaac cattagagta
    20221 caatcggttg aagaaagaaa cattgtctgt catgtgggat acaatccaga aaaacaaaca
    20281 accccttgtt aattacttga ctagaaaagc taatcttttc ggtaaagaaa aaatggaatg
    20341 gcaagatcaa gatgcaccta ttattttagg cgatttgaaa gaaaaaacct ttagttttga
    20401 cgaagcagca gcatttatta tcgaaaactt taacaaattc agtccaaaaa tggctaaatt
    20461 tgcccaatct gcttttgaaa agagctggat cgaagcagaa gatcgtcctg ggaaacgtcc
    20521 tggtggttat tgtactgagt taccagaaac aaaagaatca aggatcttta tgacctacag
    20581 taattctgtt aatgaggttg cgacacttgc tcatgaacta ggacatgctt tccatagcag
    20641 cacgatgtgg gatttacctt ctttaaatcg cgaatatgcc atgaatgtcg cagaaacagc
    20701 aagtacattc gcagaactga tcgtagccga tgctacatta aaagtcgcaa aaacaaaaga
    20761 agaaaaaatc aatttgctag atacaaaact gcaaaatgct ttagctatgt tcatgaatat
    20821 ccattcccga ttcatttttg aaaatcgatt ctatgaagca cggcaagaag gattagtctc
    20881 agaagataag atcacagaga tgatggttga ggcgcaaaaa gaaggctatc aaggagcttt
    20941 agctacttac catccatatt tctgggctgc aaaattgcat ttctttattg atgacgtacc
    21001 gttttataac ttcccataca catttggcta cctctttagt ttgggcatct atgcttacgc
    21061 caaccaaaag ggagcaaatt ttgaagaaga atatatccat ttactacgcg atactgcctc
    21121 aatgacgacg gaagatcttg cgaagaaaca tttgaatgtc gatcttaccc aaccagattt
    21181 ttggcaagca ggtatcgaca tggtgactga agatatccaa acgttcatgg aattgacaga
    21241 agaatttatc tgatttctat tttatcacaa taaaaaaaga gttagtccag aatgggctaa
    21301 ctctttttga ttaatcattc ttacatgctg acagcaaagt caggggcaaa ccattgaact
    21361 gaaccaactt ttacgctttc gcctggttga ggagcatgga tatattgtcc tccgcctaaa
    21421 gcaatcgcta cgtggtaagt tccgccttgt gacccccaga ataacaagtc tccagctttt
    21481 gcttgagaaa ctgaaatttt tgttccagct gattcttgag gaactgtcca accaccgatg
    21541 tcacgaccag ttacttgcat gtaaacatag cgtgtgaacc ctgagcagtc aaagccactt
    21601 ggatctttac cgccccaaac atatggagta ccaatatatt tgtaagcttc tgctacgatt
    21661 gctgcaccat tcacacttcc agaaggagct ggagcaggtg ttacaggttt tggttgttca
    21721 ggtgttggtg ttggcgttgg agccggagta ctacttcctg tgccgtttcc tgtatcaaca
    21781 ctttgatctg ttgatggtgt tgtaggcgca ggtgttgttg attcttctgt tgttgaagat
    21841 tcaggcactg ttgttgattc ttctgttgct gaagattcag gcactgttgt tgattcttct
    21901 gttgctgaag attcaggcgc tgttgttgat tcttctgttg ctgaagattc aggcgctgtt
    21961 gattcttctg ttgaagattc aggtgttgtt gattcttctg ttgctgaaga ttgtgtagct
    22021 gatgatgatt cttcagtcat tgaagattgt gtagctgatg attcttctgt tgctgagctt
    22081 tgtgcagtag atgaagcttg agtagcttgt gcttcagcct ctgcttgttc gcgtgcttct
    22141 ttttcagctt tttcttgtgc agcttgttga cgagcttgtt ctgctagacg ttgttgttca
    22201 cgaatacgag cttgctctgc ttcagcttct gctttttgac ggttcaagtc agctttcttg
    22261 tcttcagcag ttgcttgttc agcagctaat gaagttttca gtacgttcaa atcagcttgt
    22321 ttagataaaa gatcgccttt ttgagattcc aaagcagctt ggttttcagc taattctttt
    22381 agtttagcat cgttttcagc ttttttgtct tctacagctt ttttatcttg tttttgttgt
    22441 tccatcaagt cgttgtttgc ttttaccatc gttgtcattg cttgaacgcg tccaatagca
    22501 tctgctaatg aatcagcatt caatacagca tcgatgtagt ttgagcttgt gttgcttact
    22561 tgtgcttcgc gtgcttgttt ttggattgta tcttcacgtt tttcaatacg ttcttgtaaa
    22621 tctgcaatgt cttttactaa ttgtgcagat tcttgacgca atgtatcttg ttttgctaat
    22681 aggtcttgtg cttgtgtgtt gatttcagaa acttggcttt ctaaggcatc gatttgtgat
    22741 tgtgcatctg cttgttgatt tttcaagtct gcaatctttt gatcttgctg ttgtatctga
    22801 gaatcaaaat cgtccgccgc ggcagcgatc ggtgatgcta cggcagtcaa ggtcattgaa
    22861 cataccatta ctgctgatat taaactcttt ttcactcttc attcctccga ctggcttaat
    22921 ttaataaata tctaaatata tttaagtctt tcttaacgat ataaaaattg taccatagca
    22981 gtgtgtcaac gatataatag ttatgttaca aaaatgtttc aaaacaactt ttaaaaatga
    23041 caaaactgtt cgtttcagaa aatgatcatg aaaaagccgc gttaagtcta gcatttctta
    23101 agataacaac gattcttttt cgctttcgac ctaaaaataa aaaaagaaat tattcatcac
    23161 tgaataattt cttaaaggga aaaatgaata atacaaatat aatcatgttc aacagcagtg
    23221 taggtcctaa aaaccttgta ataaaatacg tgttatttac tactgctaat ttaaaaatca
    23281 actggaccac catcgtaaac aattcataac ccgtgacaaa gatgatcata ctgaaaaatt
    23341 cagtaaagat gttgacatgg ataacgtctt tcattacata catcaaccat acaattaaag
    23401 ggagagctac tgcatagata ccgataacgc caatatagta agcgtcatag atagccccga
    23461 gaacaatcgt ggtaatcagt aaataacgtt tttcaaacgc catactgcaa cataataatg
    23521 ccaatatcag aaagtgggca tttgacatat aggtgccttt cgaccactcc cctagcattc
    23581 ttgttaaatg accatctatc aacatcaaaa agaacaaaac gattggcaga tagtacttca
    23641 ttgtttcttt cttcaacatg gactaatcct ccgctagccg ttggacaatc gtcacaactg
    23701 acacgtcata catttctgca taaggtttca cataaacttc ccgatccagc ccataactat
    23761 ctggtttcgt tttaataacc gtaccgatcg gcaagttagc tggagaattc cctccaagac
    23821 cggatgtctg gacaacatcc ccttctttga tatccgtatc accagttaat tgggtcacca
    23881 ctaaggcatg gagcttttca tcatagtttt taagcaaacc aaacgcttcg ccattagccg
    23941 aagatacccg tactggaaaa tgattggagc tttcattaga ggatgacagt aattcgattt
    24001 tagacgaagc cgtattgacc tcgatcactc ggccaatcaa tcctttttgc gacatgactg
    24061 ccatatttgc ttcgataccg tctttagaac ccttgtctac gatcagcatg tcctgccaac
    24121 tgtcaggcga acgagtaatg acatttgccg ttactttttc gtaactagtc agcgtctgat
    24181 tcaactcaag ttcttttttc aacgcttcga tttctctctc gtaattcttg ttttgctgtg
    24241 aaacgtcatc atagctatcg attttttctt ttagccgctc attttcggca taagttgaaa
    24301 aaagattatg gacagaatct actccatttc gtacccaccg tactggggca gagattgttt
    24361 tatcaaccat tgcaacactg tcattaacga tggattggaa gaaattgggc tttccttcat
    24421 tcgctcgctg cgcagcggtc acacttagta tcgtcaccac gatgataaca ataaccaagg
    24481 taataataat atttttatta ggattgaact tcttcacaaa gacacctcga attaattaga
    24541 ctcttgtgtt caattttatc actaaatgcc gtgaaacaaa aggtaagttg ctcctcttaa
    24601 gctttttttt agcaaataat agattctgtc atttttagcc tgaaagacaa atttttttat
    24661 ttgtttatgg atcaatcttt gctttgaata actgcaatca taccatctga aaaagaaaat
    24721 tctgcggtat ctgaaagaaa ttcgttactt gcataagatg tcggatattc tacttcttta
    24781 ttttccaata catacttgct gccttttaat gtaagattcg agacgggagt caagcagcaa
    24841 taagctaaat acttcatatc tggtatctgt cttactatat gctctccagg caaataataa
    24901 gacaaataat tttgacaatc tctgataata agctgatggg caaagggttt gaagcgaggt
    24961 tccataccta accagagatt ggctaaaaga tgatccaatc ttccgcccgt agctccaatc
    25021 aaagtgactt ccgcttgcgg gtaacgttca aatgttttta agatacctaa ctgtgtatct
    25081 gtatcgtctt tttctgcagg ggaacgggta tactctttgg cttttgcaaa tacttccttc
    25141 tgctcttcgt tcgacaatga atcaaaatcg cccactgcca gatctactgg gtagcctgct
    25201 tgaagcaggt acagcgcacc acggtctatc ccgacatagg catcgtattt ggacagcaga
    25261 gactgcggcc agttttgcgg attacctcca gcagctaata aaattttcat ttagtctaat
    25321 gcctctttta atcgttcgat ttgtccgact ggattttcgg ctccatagat atatgatcct
    25381 gcaacgaaga catccgcccc tgcatcttta cagatttttg ctgtttctgg aacgattccg
    25441 ccatctactt cgattgcata agtccaattg ttctctctac gtagatcagc gagttccgta
    25501 attttttcta ctgtttcttc aataaagctt tgtccgccga acccaggatt gacagtcatg
    25561 actagtactt gatcagccaa aggcaaaaca tgtttgatca tggagactgg tgttcctgga
    25621 ttgataacta ctccagcttt aactcctaag ctttttgtca tttgaagtgc ccgatgaata
    25681 tgaggagttg cttcgacgtg gacagtaatg atatctgctc cagcttttgc aaatgctgga
    25741 atgtagtttt ctggatcaac gatcatcaga tggacgtcta acggtaattt agtaacagga
    25801 cggattgcct gaacaatatt tggccctaat gtgatatttg ggacaaattg gccatccatt
    25861 acatctacgt ggatgtaatc tgcgcctcct ttttccacta actcaatgtc tctttgtaaa
    25921 ttggcaaaat ctgcactcaa aatggatggt gctatcttca ttcttgtttc ctcctatttt
    25981 cgtttacctt ctttttttgc atacattggt tttctttttt cgatttcttg taagaattgc
    26041 aaataattgt cgtaacgtgt ctgtgcgata ccacctgttt ctactctatg ttttacttcg
    26101 cagccaggtt ctttagcatg catgcactct ctaaatttgc aatggacaga agcttctaca
    26161 aattcaggaa attgtctcgg cagttctcct gcttcaattg tcaaaaagtc aatcgagcta
    26221 aatcctggtg tatctgctac taacccgcca tagataggaa tcagttccac atgacgtgtt
    26281 gtatgccgtc ctcttccaag tgcatcagaa atctctcctg ttgctaaatt cagttccggt
    26341 gatatttgat tcagtagcgt cgattttcct gctccagact gacccataaa gaccgatagc
    26401 cgttctggga agtaacggat cagttctgtc gtatcacccg tatgattggg tacaatcacc
    26461 ggatagccta ttttagtata ggtttgcttg atctcttcga ttttttctgg gtcgtctgac
    26521 aagtcggtct ttgtcaaaaa aataatcggt tcgatcgact cgtattccaa ggtaactaga
    26581 aagcggtcaa gtagattata agaaaatgca ggctctacga tacttgtgac aatgattcca
    26641 agatcaacat ttgtgactgg tgggcgaact aattgatttt ttctcggcaa gatttccaga
    26701 agatagccgt ctgtttgatt ttcactctca aagatcacct gatctccgac aagcggcgtg
    26761 attttccgat tccggaaatt tcctcttcct cttgtttgat aggtctctcc gtttgcgtat
    26821 acatagtaaa aaccgctgat tgcttttctg atttgtcctt tgataagtgc cacctccgtt
    26881 tttgtttatt ttaccatacg aagaggaaag taggtgttat tccatgcaaa cttctcaaag
    26941 tatatggctt gaaaattgat caaaagagat agaaacacaa aaaagagaat gcaacaaatc
    27001 aatgtcgcat tcccttctga tatattttat tcagcactta ttttgaactt tctgaggtgc
    27061 tagctgatga acttgtggag ctggaagatt cttcttttga agagttgctt gtgctactgg
    27121 agctacttga gctgctagaa ctgtctgaag agtctttttc agaactagaa gacgctggat
    27181 ctggtccttt agagtaaatt acgttcacaa ccattccttt ggtaattgtc gttcctgccc
    27241 ctggtactgt acgaatcact ttatctttat ccaccgtgtt tgaatattcg gaagtctcat
    27301 gcccgatata ttctgcaccg acactagcta aataactttg tgcttcgctt tttgtatagc
    27361 cggagatatc attcaattta ggctctgttc cttggcttac gacaaaattg atgtaagttt
    27421 cttctgctac aacttcaccc gaggctggat cctgactgat gatcgaacct gatggtacag
    27481 tgtcgctata gtcataagta gcactaatat tattgatatt gaatccttgt gtaacaagcc
    27541 aattacgaac agtttcgtag ttttctccta catgactact caaagtcact gtttctggtc
    27601 ctttgctgac tgtgaaagta atcgtgtctg ttttaggatc gacttctgta tcttctgatg
    27661 gagattgcga aatgatcatt ccgctttcta cctctgaact gaattcctct tctttttgaa
    27721 tcaagtcagc agaaaaccct aattctttca aacttgcttc ggcatcttca taacttttac
    27781 cactgtaatc atctaatttg atttttttcg tgccgctact aatatacaga gtgacttcgc
    27841 gtttttgctt gactgtcgtt cccgctgccg ggtctgtctt cactacatta ccttcttcga
    27901 ttttgtcatc tgcaatttct tctgtttttg ttgctacttc taatttcgct tttgcgagtg
    27961 tttctctagc agaagcttca gaaagatcag aaacatcagg aacaacaact tctcctcgcc
    28021 cgccagaagc aaagaataca gctgttccga ttcctaaaac agcaagaata gctaatagga
    28081 tcagccacca ttttttctgt cctttctttt taggatcagg cagaacttct tcctcctctg
    28141 gcaaggtttc gttttctggc ttgtcttttg gcagaggcat agatttgaat gaatcaggca
    28201 ttggtgcatc ttccgtaagg ggtgtgataa cttttgtttc attatccatc acatgaggct
    28261 gccatttttc ttcgtttgca cgagctggtg ataatactgt agaaagatca tcagacattt
    28321 cctcggctga cttataacgg tctgcaggtt ctttagccgt tgcccgtaaa atcacgtttt
    28381 ccagtgcttg tggcacattt ggatcaagtg cttttataga tggaagatca tcttgaaaat
    28441 gttttaaagc aattgttaca gcagattcac catcaaacgg tacgctaccc gtcaacatct
    28501 cataaaggat gatccctaaa gcataaatat ctgactgctt cgttgccata cttcctctgg
    28561 cctgctcagg ggacagataa tgaacagatc ccagcatcgt attcgtctgc gtgatcgatg
    28621 tttcagataa agcgatagca atcccgaaat ccgtgatttt tacaacacct tcattatcga
    28681 tcagtacgtt ttggggtttc aaatctcggt ggatgatttg atggttatga gctaaagaaa
    28741 tagcagaaag gatctgctgc ataatattta ctgctgtttc ataaggaaca ggataatgtg
    28801 tttggatata tcgtttcaag tccattcctt tgacgtattc catcaccaga tactgcatgt
    28861 tgtcttcttc accaacatcg taaacactaa caatgtttgg atgaacgagt tctgttgctg
    28921 ctaaagcttc tctctgaaat cgtcgaatcg cagtctggtc attttgaaag tcaaatcgta
    28981 agactttaac tgctacatca cgatccaaga ttaaatcgtg cgccaaaaat acatttgcca
    29041 taccaccgct accgatattt ccagtgattt gataacggcc atttaatttt ttgcccaact
    29101 cgatcataca ctgtcctcct tatattcgat aagaagaacg gtgatattat ccgctccgcc
    29161 tgcttcattg gcacgatcaa tcagctcagt tactttatga gacaatgggc cttcttgatt
    29221 gatgatcgtt cctatttctt cttcagacag catgttcgtc aagccatctg aacataacag
    29281 cagtcgatct tttagttgcc aaagatgagt agaaacatct acttcgactg ttccaggcat
    29341 gccgacagaa cgtgttaaaa tatttttcct tggatggttc actgccattt cttcgctgat
    29401 ttctcctgat ttgactagtt cattgactaa agaatgatcc tccgtcaatt gcatgatttt
    29461 atcttcacga atcaaataag ctctgctatc cccaacattg gcaatcgtga accagtcatc
    29521 tgacagagcg gccgctacga ttgttgttcc cataccgtta tattccggct gttcttgtcc
    29581 acgctgataa atcagcatat tttcttcttg aatcgattga atgaaccatt gggcgatttt
    29641 ttcatcgtca acagcttctt gtttttccca agcttcgcct agattcgtta ccgccatctg
    29701 actggcaatg tctccggcac gatgaccacc catcccgtct gctaatacag caagcttgag
    29761 acctgaacgg ctggtaaata cactggcata gtcttgattt gtgttacgtc gtcttcctac
    29821 atctgattga tattcaatct gcattttttc acctcattac tttttgcgca aacaacaaat
    29881 gaaaaatcca tctgtgtaaa actgatgcgg atacaaagtc aacattttct cttcgattga
    29941 tgattgtagc ataggattgg tcaaaacatc aatcctctca aaatcagggt gtctttccaa
    30001 gaaagcagaa acaacgtctt ggttttcttc ttttaagatc gtacaagtgc tataagtcag
    30061 aataccggaa gactttaaag ttggtgcgca gctttctaaa atttccaatt ggatttttgg
    30121 taaattcgct aattcatccg gctgtttttt ataacgaata tctggttttc gccgaagcag
    30181 cccaagacct gaacaaggcg cgtctactaa aatccgatca aactgctctg cttcgaactg
    30241 tttactgact tctctagcat ccatcttttg agcgtagaca gcagaagaga cacctagacg
    30301 tgctgcatta tcttcaatga gtttgacttt gtgttcgtgt acatctaaag cgaccacttc
    30361 tccaccgcat gacggatcta aaaaagaagc aatatgcgtc gtcttacctc cgggtgctgc
    30421 acaggcatct aagacatgat gttcaggctc gatttgcata gacggcgcta caagcatcga
    30481 actttcatct tggatcgtca tgacgccatc gtggaacaat gagctagaag ctaaatgccc
    30541 ttttttcgct actataccgt atggactgac ttggcttttt tcagctgtga tctcttcttc
    30601 ttgcaaaaca gtgatggcct gatctctgga aagtcggcgt gtatctactc gggcactagc
    30661 atggctaggc tgatatagcg ataaaccgag cttttcagtt tcttcgtatc cgatttgatc
    30721 caccagtcgt ttcgtcatcc atagaggcag gctgattttg acagaaagtc tttcgatagg
    30781 atcagcaatg ccttgcagat ctggtgctcc ttgacgctga taattcctca agacaccatt
    30841 tacaaatttc cctgtcccag gatttccttt tacttttgcg atttcgaccg cctcgtttaa
    30901 aatagcatgt gcagggactt tatctaaaaa ttctaattgg tatacagaaa gataaagaag
    30961 cgtcttgacc cagtcatcca ctttttttgc tttagcgatc aatggtgcaa cgtaaaattc
    31021 caatagtcgc tgatggctaa tcgtaccata gatcaattct gtaaataaac ccacatcttt
    31081 ttgatttagc tcgctttgtt tgatcatctc attcaacaaa agattcgagt aggcgccacc
    31141 cttgttcact cgctctaatg tcagtaatgc catatatcgt actgattttt tcattttttt
    31201 agggattttt ttcattattt cacctgctga ccaatctgaa cttgctgacc gcttccgtta
    31261 aggaaatcat gtacggcctg ttttccttta ccagctggct gtaattcatt gatggctaag
    31321 acggtctgtt taccgcaagc aatccataga ttttttttgt ctttccggat gatcgtacca
    31381 ggtgctttgt ctgtagtttc tgccaatact tcaaccgata ataatttcca gcgtatgccc
    31441 tcataggtcg tgaatgcaat tggccaagga cgcattccgc gtacttggtt gtcaatttct
    31501 tctgcagttt tatgccaatc gattgcttct tgttcccgtg tgatgtttgg cgaaaaagtt
    31561 gcttctgact cgtcttgagg tactggtttt tgtccatcca aaatattggg caatgtttct
    31621 agcaatagct ttcttcctaa aaggctaagc ttttcaaaca tcgtccctac atcatcttgt
    31681 ttagtgattg gtatgctttc ttgcgcatag attccgcctg catccatttt tttgatcatt
    31741 tccatgatcg ttacaccagt ttctttctcc ccattcatga tggcataatg aacaggcgca
    31801 cctccccgat atttaggaag taaagaagca tggacattga ttgcccctaa ttttggtact
    31861 tgcaataact tttcaggcaa gaattggcca aatgccgcag tgacgatcac atcaggcacc
    31921 aattcaatga tttcttccat ttctggcgaa ccggagattt tctctggctg cagcacacgg
    31981 ataccgtgct tcagagccgc ttcttttacc ggtgtcggcg taattactcg tttccgccca
    32041 actggacggt cgggctgtgt taccactgcc tggatctcgt aacctgattc tatcagccct
    32101 tcaagaatcg gcacagaaaa agcaggtgtg cccataaata ctagcttagt catcaagatg
    32161 ttcctccata tattcttcaa gttcttcttc cgggatctgc tgtatcattt tctcaatgaa
    32221 caagataccg tctaagtgat cgatttcatg ctggaaggca cgggctaaat agccaaaagc
    32281 cgtcacttct atctcttctc cgtctcgatc ataataacgc acggtcactt catctgctcg
    32341 cttgaccgtt ccatagacat gcggaatact gagacaacct tctacgtcaa ggctttcacc
    32401 ttttgcttcg atgatttctg ggttaatcag ttcaaatttc tcgccttcat ctacttcgat
    32461 cacagcaatt ctcttgtttt gtcctacttg aggagcagcg atccctattc cgtcattcgc
    32521 aatcattgtc tcatataaat tgtctaataa agcgattgtc tcgtccgtga ttacatcgat
    32581 tggctgagca gttcttttta atttatcatt agggtggatc aatataggat agcgcataat
    32641 ttggcccttt cttaaataaa gtttaatggt tcgttgtcaa ttgccacaaa aagaccttgt
    32701 cgctgttctt tctggcttcc attcaaaatt tcatccaaaa catgaggaag attcggttca
    32761 tgtttatatt tgatgattag ttgataataa tatcggtttt tcactctcaa aatcatgctg
    32821 ggcgttggcc ctaatagcaa gctttgaggg cttaacactt cttttagctg attggcaatc
    32881 tgaaagattt tctttgccgc tacttgttct tcaggatggc tggcggttat tttcacagta
    32941 aagtaataag gaggatagcc tccacgatgc cgtacatgca tttcctgctg ataaaactgc
    33001 tcataatttt gttttttagc taattctatg gcgtaatgtt gaggattgaa tgtttggatc
    33061 acgacttcgc ctgctttttc cgctcgccct gctcgtcctg aaacttgggt aagcaattgg
    33121 aatgtatgct cactagaacg aaaatccggt aaattcaggg aggtatcagc attcaacacc
    33181 ccaactaatg tcacttctgg aaagtccaaa cctttagcaa tcatttgtgt ccctaataat
    33241 atatctgctt cttttgcacc gaatttttgt aaaatctgtt cgtgtgcccc ttttcttcga
    33301 gtggtatcta catccatacg caaaatccta gcttgcggat aaagttctcg gagttcctct
    33361 tctacttttt gagtacctgt tccatagtag cggattttat tgccgccaca attaggacag
    33421 cgattgggaa taggttcttc atgtccgcaa taatggcagc gcattgaacg tgtatccata
    33481 tgcagtgtaa gagagatatc gcaattagga catggaagaa caaatccaca gtccctacac
    33541 atcacaaaag acgaatatcc tcgacgattg agcagtagga cagtttgttc ttttttgtct
    33601 aatcgatttt gtattttttc ctgcaaatta gcagaaaaag tagaggtccg atgattctga
    33661 aactcttcac gcatatctac gatctcaata gctggaagct gtgcagctgc tttggctcgg
    33721 tggtttaact gcaataactg ataaacgcct ttttgagctc gtgctcttga ttctaaagag
    33781 ggcgtcgcgc ttcctagaac tattgggcaa tgatgatatt tactgcgcca aattgctaga
    33841 tctctcgcat gataacgcgg tgtctcatct tgtttgtaac ttgattcatg ttcttcatcg
    33901 ataatgatca gcccgatatt tttcagcggg gcaaaaatag cagatcgtgc gcctactact
    33961 acttgcgctt cttcccgctc aatcttgcgc cattcatcat atttttcacc ttgggaaagt
    34021 ccgctatgta agaccgcaac tgattctccg aagcgtcctt tgaatcgctc gaccatttgc
    34081 ggagtcaatg cgatttcagg cactaacata atagccgttt tattttctga caaaacatca
    34141 gcgattgcct gaagatatac ttctgttttc ccgctgccag tgattccctc cagcaaaaag
    34201 acctgatctt tttgctgctg acctgctgtg atgatttgtt cgacagcatt tttttgttct
    34261 gcattcagtt ccaatgccgt cgtttggtca aatactcggt ctttataagg gtcgcgataa
    34321 cgttctgatt ctataaactc cagccagccc ttttcttttc cttgattcaa gacagcagta
    34381 ctgattcctt tatttttgaa ataagcaatt ggttcttctt ggctcagttc agataaacac
    34441 aaaagaagtt ctttttgttt cttggcattt tgccgtaatt ttgcccattc ttcttcgatt
    34501 tgcttttcag ttaacaaaga acggaccaaa cgaatcgttt ttactttatt tcgtgtatgg
    34561 acttcatatt tgatatctac taattgctct tggcgccagc gaatcaattg agaaaggctg
    34621 ccttcttctt ctgcttcctt ccaggaaatc acttctcgct gatcaaacaa tacctgaact
    34681 tctggtgtgt ctgccaaagg atagatcaat ttatcatatt ctgctttcat cacactcgga
    34741 agcatcgttt gtagacaagt gattttgaat gcgtaagtaa tttttttcat ataatcagct
    34801 aatgaaagta attcttcatt gaccaccgga gcaaggtcta gcaaacgaat aactgccttc
    34861 aaagatggat tagctgattc ttctgatttt tggatagcca taacaaatcc ttggacatga
    34921 cgattgccat taccaaaagg gacttctact cgcatcccga cttgcaaagc tgtttccatt
    34981 tcagagggaa ccaaataagt gaatggctga tcggtctgca tagtaggtac gtccacaatg
    35041 acttcagctg ttaatgtcat ggttcgtttc ctcctttttt tgtcttttct tatcaagcga
    35101 caaaaagttc cttgcctatt ttactagaga tcgatggatt tgtcttatct tctgccaaat
    35161 cctaacaaaa aattaacagc agataagaaa aaaaagaact gtgtcaaaaa gttcagacac
    35221 agccttttct accagacaat aagtggcgaa tgtttgaaaa ggaaacagct gggtttgctt
    35281 ttctttttag atgttcgctc tatttttctt tattacattt tttgctcttc acggatacgt
    35341 gattccaatt cgtgttgttc acgctctttt tgtgcttgac gttcctcttc ttccatcttc
    35401 aaacgttcac gttttaattc aggatgtgga tcattgacta catttcctgc atcgatttct
    35461 tctaaagctt gaccgacgct ttttactgaa tcaaaagaat ctagagtagg ctgtgcactt
    35521 gcatccaatt catgcgcgcg tttacttgct aaaatcacta gagaatattt tgaatttaca
    35581 cgatctaata gtgagtcaat tgaaggtttt aacatcataa gactacatct cctttaacat
    35641 tttaatatat ttaccgatta cgcgatctac tcgaaaatgt tcactggcaa taatgttttt
    35701 gattcgttca actgctagcg gcacttcatc atttacaaca gcatagtcgt aaagagccat
    35761 catttcgatt tcttcttttg caactttcat tcgttcttcg attacttcat ctgcatctgt
    35821 tcctcggcct acgatccgtg attttaattc cgctaaatct ggcggagtca aaaagatgaa
    35881 tacaccatcg ggcacttttt ctttgacttg ttttgctcct tggacttcaa tctccaagaa
    35941 aacatctttt ccttcatcca atgtcttgtt gatatatgac aaaggagttc cataataatt
    36001 cccgacatat tctgcgtatt ccagcatctc tccagcttcg atcattgatt caaactcttc
    36061 tttgcttcgg aagaaataat caacgccttc gacctcccct tcacgcattt tacgggtagt
    36121 cattgagatc gaatactgaa aatcattatc ctcactctca aaaattgctt ttcgtactgt
    36181 gccttttcct acaccggatg gaccagacaa cacgattaat aatccacgct ctgacatgac
    36241 gacgtccttt caactagtct ttttgtactt atcgtttatt ttgcactttt tttctgcaac
    36301 tttcaaggtt atctttaatt atagctagaa attggtaaaa aagctaccct gtaccaagag
    36361 gtcgtaaaaa agctgtcctg catcaagtaa taagaacagc caaacataaa cagcttctca
    36421 tgtttttcgt ttggttgggg ttattatcgc agatgcaagc ttttgaacgc cgtgtataag
    36481 aggtcgtgaa gaagccgatt agtttcgagt atgaagaaaa attttgtgaa aatagtttct
    36541 cacatttttg cataaatttg gcttaatac
//
LOCUS       DACGEU010000018        35882 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.018, whole genome shotgun sequence.
ACCESSION   DACGEU010000018 DACGEU010000000
VERSION     DACGEU010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 35882)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35882)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35882
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.018"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            <1..1152
                     /locus_tag="IXR40_000844"
     CDS             <1..1152
                     /locus_tag="IXR40_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005236379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360714.1"
                     /translation="PSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSA
                     EAPKEKVETSGSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKED
                     IENFLAGGPSSAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPT
                     RKAIAKAMVNSKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALT
                     ATVKKYPVLNASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEI
                     NEKAKLAHDGKLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIV
                     NAEGEIVVGRVMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            1160..2566
                     /gene="lpdA"
                     /locus_tag="IXR40_000845"
     CDS             1160..2566
                     /gene="lpdA"
                     /locus_tag="IXR40_000845"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HAQ4360715.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            2728..3003
                     /locus_tag="IXR40_000846"
     CDS             2728..3003
                     /locus_tag="IXR40_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HAQ4360716.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            3009..3776
                     /locus_tag="IXR40_000847"
     CDS             3009..3776
                     /locus_tag="IXR40_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HAQ4360717.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            3944..5773
                     /gene="typA"
                     /locus_tag="IXR40_000848"
     CDS             3944..5773
                     /gene="typA"
                     /locus_tag="IXR40_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HAQ4360718.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            6034..7806
                     /gene="recQ"
                     /locus_tag="IXR40_000849"
     CDS             6034..7806
                     /gene="recQ"
                     /locus_tag="IXR40_000849"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HAQ4360719.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            7920..8222
                     /locus_tag="IXR40_000850"
     CDS             7920..8222
                     /locus_tag="IXR40_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HAQ4360720.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            8225..9388
                     /locus_tag="IXR40_000851"
     CDS             8225..9388
                     /locus_tag="IXR40_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HAQ4360721.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            9414..12842
                     /locus_tag="IXR40_000852"
     CDS             9414..12842
                     /locus_tag="IXR40_000852"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HAQ4360722.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            12863..13987
                     /locus_tag="IXR40_000853"
     CDS             12863..13987
                     /locus_tag="IXR40_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360723.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            13977..14414
                     /locus_tag="IXR40_000854"
     CDS             13977..14414
                     /locus_tag="IXR40_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HAQ4360724.1"
                     /translation="MIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESAKVC
                     QLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQLQS
                     LLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            14398..14736
                     /locus_tag="IXR40_000855"
     CDS             14398..14736
                     /locus_tag="IXR40_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HAQ4360725.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            14855..15415
                     /gene="rsmD"
                     /locus_tag="IXR40_000856"
     CDS             14855..15415
                     /gene="rsmD"
                     /locus_tag="IXR40_000856"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HAQ4360726.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            15412..15903
                     /gene="coaD"
                     /locus_tag="IXR40_000857"
     CDS             15412..15903
                     /gene="coaD"
                     /locus_tag="IXR40_000857"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HAQ4360727.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            15893..16936
                     /locus_tag="IXR40_000858"
     CDS             15893..16936
                     /locus_tag="IXR40_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HAQ4360728.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            17095..17823
                     /locus_tag="IXR40_000859"
     CDS             17095..17823
                     /locus_tag="IXR40_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComEA"
                     /protein_id="HAQ4360729.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            17939..18184
                     /locus_tag="IXR40_000860"
     CDS             17939..18184
                     /locus_tag="IXR40_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HAQ4360730.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            18181..18399
                     /locus_tag="IXR40_000861"
     CDS             18181..18399
                     /locus_tag="IXR40_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HAQ4360731.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            18535..19074
                     /locus_tag="IXR40_000862"
     CDS             18535..19074
                     /locus_tag="IXR40_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HAQ4360732.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            19067..21340
                     /locus_tag="IXR40_000863"
     CDS             19067..21340
                     /locus_tag="IXR40_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HAQ4360733.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            21378..22424
                     /gene="holA"
                     /locus_tag="IXR40_000864"
     CDS             21378..22424
                     /gene="holA"
                     /locus_tag="IXR40_000864"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HAQ4360734.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(22513..22767)
                     /locus_tag="IXR40_000865"
     CDS             complement(22513..22767)
                     /locus_tag="IXR40_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HAQ4360735.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(23167..23436)
                     /locus_tag="IXR40_000866"
     CDS             complement(23167..23436)
                     /locus_tag="IXR40_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360736.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            complement(23906..24361)
                     /locus_tag="IXR40_000867"
     CDS             complement(23906..24361)
                     /locus_tag="IXR40_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HAQ4360737.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            complement(24499..26427)
                     /locus_tag="IXR40_000868"
     CDS             complement(24499..26427)
                     /locus_tag="IXR40_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HAQ4360738.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            complement(26624..27457)
                     /locus_tag="IXR40_000869"
     CDS             complement(26624..27457)
                     /locus_tag="IXR40_000869"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HAQ4360739.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            complement(27649..28353)
                     /locus_tag="IXR40_000870"
     CDS             complement(27649..28353)
                     /locus_tag="IXR40_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAQ4360740.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFKQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            complement(28376..29002)
                     /locus_tag="IXR40_000871"
     CDS             complement(28376..29002)
                     /locus_tag="IXR40_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAQ4360741.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            29328..31703
                     /locus_tag="IXR40_000872"
     CDS             29328..31703
                     /locus_tag="IXR40_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HAQ4360742.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            complement(31727..32218)
                     /locus_tag="IXR40_000873"
     CDS             complement(31727..32218)
                     /locus_tag="IXR40_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HAQ4360743.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            32405..33325
                     /locus_tag="IXR40_000874"
     CDS             32405..33325
                     /locus_tag="IXR40_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAQ4360744.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            33479..33823
                     /locus_tag="IXR40_000875"
     CDS             33479..33823
                     /locus_tag="IXR40_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HAQ4360745.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(34013..34513)
                     /locus_tag="IXR40_000876"
     CDS             complement(34013..34513)
                     /locus_tag="IXR40_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4360746.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            35041..35124
                     /locus_tag="IXR40_000877"
     tRNA            35041..35124
                     /locus_tag="IXR40_000877"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35075..35077,aa:Leu,seq:cag)
     gene            complement(35448..>35882)
                     /locus_tag="IXR40_000878"
     CDS             complement(35448..>35882)
                     /locus_tag="IXR40_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HAQ4360747.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPVQAEQPVVQET
                     VQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQL
                     DSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT        11868 a         6261 c         7405 g        10348 t
ORIGIN      
        1 ccgtcacctg tcacagggac agttaaaaac gtgattgttc cagaaggcac tgtagcaaat
       61 gttggggatg tattagtaga aatcgatgct cctggacaca atagtgcacc gtcaactagt
      121 gcgccatcag ctgaagcacc aaaagaaaaa gtggaaacat caggttcagc aagtgtcgtt
      181 gaagctgccg atccaaataa acgtgtattg gctatgccat ctgttcgtca atttgcccgt
      241 gaaaaagatg tagatatctc acaagtaact gcaactggaa aaggtggcag agtaacaaaa
      301 gaggacatcg aaaacttctt ggcaggtggt ccaagcagtg caccagcgaa atcagaagcg
      361 ccagaagcgg cagcaccgaa agaagcagct cctgcagcag aaagcaaacc agctgcacca
      421 gcaaaaccat tcaagtccaa cttaggagac ttggaagaac gtgtagcaat gacgccaaca
      481 cgtaaagcta tcgctaaagc aatggtcaac agtaagcata cagctccaca cgtgacattg
      541 catgatgaag tagaagtgtc taaactatgg gataatcgga aacgatttaa agaagttgct
      601 gctgcaaatg gtacgaaact tactttcttg ccatatgtcg tgaaagcttt aacagcgact
      661 gttaagaaat acccagtatt gaatgcatct atcgacgatg caaaccaaga aatcgtttat
      721 aaacattact acaatatcgg tattgcaact gatacggatc acggactata tgtaccaaat
      781 gtgaaagatg cagaccgcaa aggaatgttt gctattgcag acgaaatcaa tgagaaagca
      841 aaattagctc atgacggcaa actatctgca gaagatatgc gcaatggaac aattacgatc
      901 agcaatatcg gatctgtagg tggcggttgg tttacaccag tcatcaacta tccagaagta
      961 gctattttag gtgtaggaac gattgcacaa caaccaatcg taaatgctga aggcgaaatc
     1021 gttgtcggtc gtgtgatgaa actgtcatta agtttcgatc accgtatcgt agatggagca
     1081 actgcgcaac aagcaatgaa taatatcaaa cgtcttttag ctgatccaga gctattaatg
     1141 atggaaggat gataaacaaa tggtagttgg agattttgct gtagaattag atacagttgt
     1201 aattggtgcg ggacctggtg gctatgtagc tgccatccgc gctgctgaaa tgggacaaaa
     1261 agtagcaatc attgaaagag agtatattgg cggtgtttgt ttgaatgtcg gctgtattcc
     1321 ttcaaaagca ctgatagctg caggacacca ttatcaagag tcactagatt ctgaaatgtt
     1381 tggagtaact agtgaaaacg tcaaactaga ttttgcaaaa acacaagaat ggaaagaaaa
     1441 caaagttgtc catacgttga cttctggtgt tggtttccta ttaaaaaaac ataaggttga
     1501 aacaatcgaa ggagaagcgt tcttcgtaga tgatcacaca ctacgcgtca ttcatccaga
     1561 ttcagctcaa acttattcgt tcaataacgc aatcatcgca acaggttccc gtccaatcga
     1621 gattccagga tttaaattcg gaggacgtgt gttagattct actggcggat tagcattgaa
     1681 agaagtacct aagaaatttg tgatcatcgg tggcggtgtg attggtgccg aattgggcgg
     1741 agcgtacgca aacttaggag cagaagtaac gattcttgaa ggctcaccac aaattttacc
     1801 aacttacgaa aaagatctag taaaattagt agaagatgat ttcaagaaaa aaggcgtaac
     1861 agtcgtaacg aatgcaatgg cgaaagaagc agtcgataac ggtgacagcg tgacagtgaa
     1921 atatgcagtg gacgggaaag aagaatccgt tactgctgat tatgtgatgg tcactgtagg
     1981 tcgtcgtccg aatacagatg atatgggctt agaacaagcg ggtgtcgaag taggagaacg
     2041 aggattgatc acggtggata aacaaggacg tacgaacgta cctaacatct atgccatcgg
     2101 tgatatcgtt ccaggggcgg cattagcaca caaagccagt tatgaagcaa aaatcgctgc
     2161 tgaagcaatc tctggcaaaa aagtagctgt agattataaa gcaatgccgg cagtagcctt
     2221 cactgatcct gaattggctt ctgtaggtat gacgatcaaa gaagcaaaag atgctggtat
     2281 cgaagcaaaa gcatataaat tcccattttc agggaacggt cgggcattat cgcttggtaa
     2341 aacagaagga ttcatccgtc tagttacgac gatcgaagat aacgtgctta ttggcgcgca
     2401 aatcggtgga gtcggcgcaa gtgatatggt ctctgaatta gctttagcaa tcgaatcagg
     2461 aatgaatgct gaagatatcg ccttgacgat tcatcctcat ccatctcttg gcgaaatcgt
     2521 catggatgct tcggaattag cattaggttt accaatccat atttgatttg aataatacag
     2581 gcgaaacgca actgaaaaat cagttgcgtt ttgtttttta gaattatcaa taatattatt
     2641 atgtaaactt aaaaatatga caacttcttg gtttattacc acttcctatg ctacactgaa
     2701 gaggaatatg aaataggaga gttgaagatg caagaatatc agtatccact tgatttagat
     2761 tggacaacag acgaaatggt cattgtaatg aagatgtggg aagatctgga acgtgcgaat
     2821 gaaaaaggga taaacaatga agcttttttg aagacttatc agcagtttaa aactgttgtc
     2881 aaatccattg gtgaggaaaa acgattggga cgggaatttg aaaaagcttc cggttattct
     2941 ttatatcgta cagtgcagca agcaaaaaaa aatccaaaca aaactttgag aatgaacggg
     3001 tgagataaat ggaacagatg attgatcata tcaagtcctg gcttgaagaa gctggtgaga
     3061 aaatcaaatc ttctcaacaa acattaacaa tctcgcaaaa atcaaatcga acggatctag
     3121 taacaaatgt cgatcgaaac atccagaatt ttctaatcga aaaaatccat tcctttgatc
     3181 cagaggcgaa aatattggca gaagaagaag ggtgtaatca attatcggat ctcgatggaa
     3241 gagtctttat catcgatcct attgatggca ccttgaattt tgtgattgaa ggggaaaatt
     3301 tttgtattat gctcgctgtt tatgaatccg gcgttggaaa gcttggtttc atttatgacg
     3361 tgatgagaaa tgaacttttt tggggtggaa aaggaatagg cgtgtataaa aatgatgagc
     3421 cattgcctag accagcaaat aaatccttat cggaaggctt acttggtgtg aatagttatc
     3481 ttttcggtca taataaatat ggaatccgag aaattgcgga aagcagcatg gggacacgta
     3541 tgtacggatg cgctggtctt gaactagtgg caatcttgaa aggaaaccac attgcttata
     3601 tttcaaacct tagcccttgg gattatgcag cgggaaatgt cttattggaa gagtttggta
     3661 tggtaacaag cggtcttttt ggtactcctt tgacatttga aaaaagggaa tactatttag
     3721 cagggacttc ttgtgcatat gcagaaatcg cagacctttt gaaaaaagaa ggctgaaaaa
     3781 aaggtagaaa tcattcacaa aaatgataaa aacgagcaaa agattaattt tctcgaaaaa
     3841 atgaaaacat tttactatat ttcatgaaaa aagtctgcta taattagcag tcgagtaaaa
     3901 tttgccctgt cataaagaac caataaaaaa ggagttagtt acattgaatt atagaaacga
     3961 tatccgtaac gtcgcaatta ttgcccacgt tgaccacgga aaaacaacat tagttgatga
     4021 actattaaaa caatcagata cattagacgc acatacgcaa ttgcaagaac gtgcgatgga
     4081 ctcaaatgcg ctagaaaaag aacgtggtat cacgatttta gccaaaaaca cagctgtaga
     4141 ctataaaggt attcgcgtaa acatcatgga tactccagga cacgcggact tcggtggcga
     4201 agtagaacgg atcatgaaaa tggttgacgg cgttgtgttg gtcgtagatg cgtatgaagg
     4261 aacaatgcct caaacacgtt ttgtattgaa aaaagcactg gaacaacata tcacaccaat
     4321 cgttgtcgta aacaagattg acaaaccttc tgctcgtcct gagcatgtcg tagatgaagt
     4381 tcttgaacta ttcatcgaat taggagcaga tgatgatcag ttagactttc ctgtgattta
     4441 tgcatctgca ctaaatggta cgtcaagctt gtcagatgat ccagcagatc aagaaccaac
     4501 catggcacct atttttgata caattattga aaaaatccct gctcctgtcg ataacagcga
     4561 cgaaccatta caattccaag tttcattact tgactacaac gattatgtag gtcgtatcgg
     4621 aatcggacgt gtatttagag gaacaatcaa agtaggagac caagtagcat taattaaatt
     4681 agacggaaca gttaagaaat tccgtgtaac gaaattattt ggtttctttg gactaaaacg
     4741 tctagagatt caagaagcaa aagctggaga cttgattgct gtctcaggta tggaagatat
     4801 ctttgtcggt gaaacagtta ctcctgtgga tcatcaagat gcgttaccta tccttcacat
     4861 tgacgaacca acattgcaaa tgactttctt agttaataat tcaccatttg ccggtcgaga
     4921 aggtaaattc gtaaccgctc gtaagattga agaacgtttg atggcagaac ttcaaacaga
     4981 tgtatcctta cgagttgaac caacaaactc tccagatgca tggacagttt ctggtcgtgg
     5041 agaattgcat ttgtctatct tgattgaaaa catgcgccgt gagggatacg aattgcaagt
     5101 atctcgtcca gaagttattg aaaaagaaat cgacggtgta aaatgcgaac cgtttgaacg
     5161 cgtgcaaatc gatacaccag aagaatatat gggtagtgtt atcgagtcct tgagcttacg
     5221 taaaggtgaa atgcaagata tggtccatac aggaaacgga caaatccgtt tgacattctt
     5281 aacacctgcc cgcggtttga ttggttattc aactgaattc ctttcaatga cacgtggtta
     5341 cggaatcatg aaccatactt ttgaccaata tctgccaatg cttcctggtc aaattggcgg
     5401 acgtcaccaa ggggcgcttg tttcgatcga tacaggaaaa gcaacgactt attctatcat
     5461 gagtatcgaa gaacgcggta cagtcttcgt agaaccaggt acagaagtat atgaaggaat
     5521 gattatcggg gaaaacagcc gtgataatga tttgactgtc aacatcacga aagcaaaaca
     5581 aatgacaaac gtacggtctg ctactaaaga ccaaacatct gtcatcaaaa aaccaaaaca
     5641 attgacgttg gaagaatctt tggaattctt gaatgatgat gaatattgcg aagtaacacc
     5701 agaaagcatt cgcttgagaa aacaaatttt agagaaaaat gctcgtgaaa aagcatctaa
     5761 aaagaaaaaa taatctgtaa aaggatgaag agagaaacca gcttgttata aaaaatagct
     5821 ggtttctttt tttgtccaac tcttttctgt ggagaagtca tctttgtcaa tggacataaa
     5881 ttcagaaaat acgccgaaag acgtttaaaa gacttttaaa aaacttattt ctagagagtt
     5941 tttgtttcat aataagataa tgtttcacga aaggagatca acttgtcctt cgaagaaaat
     6001 cgaagtaaaa tggcaagaga aaggagcggg aagatgaacg acttattaaa acaatacttt
     6061 ggctatgatg agtttagacc tggtcaaaaa gaaattatcc agaaagtcat tgatcaggaa
     6121 aatgtattag gaatcatgcc taccggaagt gggaaatcaa tctgttacca gcttccagct
     6181 ttactattag atgggcttac tgtggttgtg tcccctttaa tctctttgat gaaggatcag
     6241 gtggacgcgg cgaatcaatt aggtataccc gccactttta tcaatagctc gttagatggt
     6301 tacgaaacag ctagacgctt ccaagaaatc gatagacagc agtaccgttt actttatatc
     6361 gctcctgaac gttttatcat gccggatttt atccaagcaa tgaagcgatg gaacgtccgt
     6421 atgatcgcta ttgacgaggc acattgtatc tctcagtggg ggcatgattt ccgcccaagt
     6481 tatttacaga tggcgaacca gctagatcaa ctgccaaatc gtcctgtaat tgttgctttg
     6541 acagctacag cgactgtgca agtagctgct gacataaaaa gacttttaaa aattccagaa
     6601 aacaaccata ttcagactgg ttttgaacga gaaaatctac gatttcaagt aattaaagat
     6661 caaaaaaaag aacaatatct aatcgaatat ttaaagatca acaaaaatca atctggtatc
     6721 atttatgcag caacgagaaa agaagtagac cgtctctatc atttgcttaa aaaattcgat
     6781 ttttccgtgg gtagatatca tggtggtcta aatgagaatg agcgaacaga aatgcaagaa
     6841 gcctttttat acgatcgctt gcagctgatt gtagcgacaa atgcatttgg tatgggtata
     6901 aataaaagca atgtccgttt tgttatccat tatcaaattc ctggctctct agaagcatac
     6961 tatcaggaag ctggtcgggc gggaagagat ggtctttcca gtgaagccat cctgcttttc
     7021 tctcctcaag atatccaagt ccaaaagttt tttatccagc agtcccaaag agaagaaggg
     7081 caaaagcaaa aagaatatga aaaattaaaa gcgatgacag aatacgtgta tattgagtcc
     7141 tgtcttcagc aatacatcct aaactatttt ggcgagacaa gcagtccgtg caaccgttgt
     7201 ggtaactgtt tagatgacag agaaatagta gaagtaacga cagaagcaca gatggttctt
     7261 tcttgcttaa aacgtatggg tgagaactat ggtaaacaaa tgctgatgaa agtcttagca
     7321 ggatcgaaag aacaaaagct gcaagcttta ggttttggac atttatctac ctatggactg
     7381 atgaaaaacc aatcgcaaaa agaaacgatg cagttaattg aatatttgat atcgaatggc
     7441 tatcttctga ccatcaatgg tgagtatcct gttttgaaag taacagaaag agggatacaa
     7501 gtattgaaag gacaagaatc tgtttatcga aaggaaccca agaaagtcca gcagctatcg
     7561 gatgaagaaa ccgatacact atttgaagtg ctgcgggaac tgcgaacgga tctagcatca
     7621 gaagcaggcg ttcccccgta tgtcgtattt tcagattcca cattgaaaga aatgagccga
     7681 atacgtccat caagcagatt ggagatgctt cagataaaag gagttggcca aagcaagctt
     7741 gataaatatg gcgaagcctt tttatctcgg ataaaaaatg cggactctaa cgttctggat
     7801 aagtagaaag aacgaatacg taaaaatgaa taaaaacaac tggttaaatc tgtttttttt
     7861 gctccttatg aaaatcaaat atgttataat taaggaatta gaatgggagg taagcacaga
     7921 tggattcttt gtcgaaaaaa cttgcgatcc aagtattaaa tgatgaagca gaacggatca
     7981 aacgattaat ccgaaatcaa aacaacagtc tctgtatctc acaatgcaaa gccttcgaag
     8041 aagtggtaga tacacagatg tacggctttt cccggcaagt cggttttgct gtccgtatag
     8101 gagtaatcgg aaagaacgag ggccagctga tgttaagtga gctagaacga gaattgaatc
     8161 agttatatag tgaggtttac caagaaattt atgataaaaa agaagttggc aaggaggaat
     8221 agacttgcct aagaaagtga aaaaaaggca tctattagac tatagcatct tgattcccta
     8281 tttaatttta tgtgtattgg gattgatcat ggtatatagt tctacgtcgt atctattatt
     8341 agaaaacgga caaaatccgt ccgcatcagt cattaaccag agtatttttt gggtgcttag
     8401 cttgattgct atcgcactac tttataaaat gaaaacagat gttttgaaaa accagcgttt
     8461 gatcatggca gccatcgcag ttttgacgat tttgctgctg attgttgtgt tttttggtaa
     8521 ggagatcaat ggggcgaaag gttggctgca aattgcagga ttctcgatcc aacctgccga
     8581 atacctaaaa atcatttcta tctggtacct gtctctgact ttatctaaaa gacaaaacag
     8641 tgtacaaaaa gattttcttg ggactgtgaa acgtccactt gcaatggtta tcggacttac
     8701 tgcattagtc gctattcttc ccgattttgg taatgcggca gttatctttt tgattatttt
     8761 ggttctgctt ttagccagcg gagtcaatta tgtgtatact ttgattgtag gagtaggagg
     8821 cttttgtcta agtactttta cgatctggct gatcaatatc acaaacggaa agatcttacc
     8881 cggacgttta cagtatatct ataatcgatt tgctatttac caaaatcctt tctcagacga
     8941 attaaataaa gggcatcaac tagtcaacgg ctactatgcc atgttcaacg gaggactatt
     9001 tggcagggga ttaggtaaca gtatccagaa aaaaggattt ttacaagaag cacaaaccga
     9061 ttttatttat gcaatcgtag tggaagaact gggagtgatt atggggattt tgatattagc
     9121 gttgctattc tttatgattg tgcgcattgt ccttgtaggt atccgttcaa aagatccgtt
     9181 caattcgctt ttgtgcattg ggatcggcgc aatgtttttg atccaagtat ttgtcaatct
     9241 tggaggaatt actggcgtta ttcctttgac agggatcacg ttcccatttt taagtcaagg
     9301 aggctccagt ttgctgatgc tttcgatttg tgtcggcttt gtcctcaaca tcagtgcgga
     9361 tgaaaaacgc aagagcttag gtttataata aaaaaagatg taggagtggt tcgatgaaaa
     9421 aagttttagt tgctaacagg ggtgaaatcg ctgtacgtgt atttcgtgct tgtacagaat
     9481 taggaattaa aactgttgga atctatgcag aagaagatga atattccgta caccgtttca
     9541 aagcggatga agcatattta gtaggacaag gaaaaaaacc gattgatgcg tatctagata
     9601 ttgaagggat catttctatc gcgaaagaat gcggagctga cgctattcat ccgggttacg
     9661 gtcttttgtc ggaaaacttg aattttgcgc aacggtgcga agaagaaggc atcatttttg
     9721 ttggacccaa actgcatcat ttagatattt ttggagataa aatcaaagca aaagctgcag
     9781 ctatcgaagc ggggattgct tcgattccag gcacagatgg accaatcgct tctatagacg
     9841 atgccttgga gtttgcgaaa caatacggtt atccgattat gatcaaggca gctctaggcg
     9901 gcggcggacg cggcatgcgt gtagctcacg atgaaaagag tgcaagagag ggctacgaac
     9961 gtgcgaaaag cgaagcaaaa gcagcctttg gtagtgatga agtgtatgtt gaaaaataca
    10021 tcgctaatcc taagcatatc gaagtacaga ttctcgggga tacgcatgga aacgtcatcc
    10081 atctttttga aagagattgt tctgttcagc gccgtcacca aaaagtagta gaagtagcgc
    10141 cttgtgtctc tatgaatgaa cagcaacgtc aaaaaatctg ccaggcagct gtccaattga
    10201 tgaaatatgt cgggtatgtc aacgcaggta cagtagaatt tcttgttgaa ggagatgatt
    10261 tttactttat cgaagtcaac cctcgcgtcc aagtggaaca tacgatcaca gaaatgatta
    10321 cagatattga tatcgtaaca acgcaactgt tgattgctca aggtttggat ctgcataaag
    10381 aaatcggatt gcctcagcaa gaaggaatta aattaaatgg ttcagccatt caatgccgaa
    10441 tcactacaga agacccgttg aataactttt taccagacac agggaaaatc gatacgtatc
    10501 gttcacctgg tggttttggc gtacgtctgg atgtcggaaa tgcttacgcg ggctatgtag
    10561 tgacaccgta ttttgattca ttgctagtaa aagtatgtac gcatggtgct acctttgaaa
    10621 cagccattca gaaaatggaa cgttgcttga aagaatttag aatccgtgga gtgaaaacaa
    10681 acattccatt tatgctcaat gtcatcacac atcctgaatt ccaatcagga aatgcaaaaa
    10741 caaccttcat tgatagtaca gcaacattat ttgaatttcc tcgactacga gaccgcggaa
    10801 acaaaacgat gaaatatatc ggtgaaatta ctgtgaatgg ttttccaggt atcgaaagtg
    10861 gcgaaaaacc attttatgaa gaaccacgta tgcctaaaga tctaatcaca agaactgatt
    10921 acgtaacggc taagaatgta ttagatgcga agggtgccga tgctttggtc gaatggatca
    10981 aaggacagga aaatttgttg ttgacggata cgacatttag agacgcccat caaagtctgc
    11041 tagcaactcg tgttcggaca aaggatttca agcagattgc acgtttgact ggagaaggtc
    11101 ttcctgaact cttttcaagt gagatgtggg ggggagcaac atttgatgtg gcttaccgct
    11161 ttttgaatga agatccttgg caacggttga gaaaaattcg ttctttaatg cctaatacgt
    11221 tgctgcaaat gcttttcaga ggttcaaatg ccgttgggta ttctaattat cctgacaatg
    11281 tattggtgga atttgtcaaa gaagcagcag cgcaaggaat cgatgtattt cgaatctttg
    11341 atagtttgaa ctggactcca caaatggaaa aaagtatcca agctgtacgg gatactggta
    11401 aaatcgcaga ggcagctatt tgctatactg gcgatatcaa cgatccaagt cgggcaaaat
    11461 acaatgttca gtattataaa gacatggcaa aggaactaga acaactgggt gcgcatatca
    11521 ttgcaatcaa agatatggct gggctgctta aaccgcaggc agcttatcgt ttgattagtg
    11581 aattgaaaga aacgacagat ctgccaatcc atctgcatac tcatgatacc agcgggaatg
    11641 gaatcatcac ttattctgct gcttcaaaag caggagtaga catcgttgac gtggcaatga
    11701 gtgcaatgag tgggaatact agtcagccta gcatgagcag cttgtattat gcactggtca
    11761 atggtccacg gctgccagaa atcacgattg aaaatgcaca gaaattaaac cattattggg
    11821 aagatgtgcg catgtattac aaaccgtttg aaaacggctt gaatgctcct gaaacagaag
    11881 tatatatgca tgaaatgcca ggaggacagt attcgaatct acagcaacag gcaaaagctg
    11941 tcggattagg tcatcgctgg gatgaaatca aacaaatgta tcatactgtc aacttgatgt
    12001 ttggcgatat cgttaaagta actccatcat ctaaagtagt tggagatatg gcactattta
    12061 tggtccaaaa tgatcttaca gaagaagata tttatgaaaa aggcgaaaca ctaagtttcc
    12121 ctgaatctgt tgtgactttc ttccaaggag aactagggca acccgttggc ggatttccta
    12181 aaaaattgca aaagattatt cttaaaggca gacctgcatt gaatgaacgt ccaggtcttt
    12241 tggctgaatc agtcgacttc aacgaagtaa aaaaagaatt ggcagaaaaa attggctatg
    12301 aaccaaaaca agacgaagta ttaagctatt tgatgtatcc gcaagtcttt ttggactatc
    12361 aaaaagcata taatcaattt ggcgatgtta cattactgga cacaccaaca tttttccaag
    12421 gtatacgttt gggtgaaaca atcaatgtac aaatcgaacg cggaaaaacg cttatcattc
    12481 gtttagatga aatcggagaa cccgatatcg aagggaatcg cgtactgttc ttcaatttga
    12541 atggacaaag acgtgaaatc actatcaaag ataattcgat catcagtacg gtccaaaccc
    12601 gattgaaagc tgaaccgaca aaccgagaac aaattggagc aacgatgtct ggttctgttt
    12661 tggatgtatt agtgaaaaaa ggcgataacg ttaaaaaagg tgatacgttg atgattactg
    12721 aagcgatgaa aatggaaacg gccatcgaag cacgttttga cggagaagtc gcacatgtat
    12781 atgtgtcttc aggagacact atttcgtctg gtgacctttt gattgaagtg actgagaaat
    12841 aataagcgaa aggtggggaa acatgaaaag actgggtttg ttttggctga ttctgctatt
    12901 agttattgtg gcattctaca tggaaccagt cttgtttccg ccaaaacttg aagtgaagga
    12961 aaactctgat caacaaatat caaaccaaat gacaacgtgg aaataccagg agcttaaagc
    13021 aactggtttt tctacttata tcggaaaacc gatcgatcag ctggaaaagg attttggcca
    13081 agcctatgat cgattaacta gcggatttgg ttttgaaaca agatattatg aaaataaagc
    13141 tagtcatctc acatttgaag cgaacatcca agacagcaga gtcacaactg ttaaagtact
    13201 gcaaacaggg cctgctgata tcgcgccgtt ttatttaggg atgacgatgc aagatcttac
    13261 gaaaatcact actatctata ctaatttcac ttttgagtac catgatacag aagttggaat
    13321 cgaactaatg gaagaggata tgaattatcg tccgctaatt gcttttgata acgacacttt
    13381 tgctatttta ttttttgatc aaacaacaaa cggcctattt tcagttgtgt atttagataa
    13441 agatagtctt ttgaaactat tgccatatca agtgtttggt gaaggccttc cacattatca
    13501 agcagataaa tcggctgatt gggaatcaat caatcgcgtt aaagaacgaa aaagtacgac
    13561 tttattaaat atgcttagaa gagaagacga acttcccata tacaatcaaa cacttgcctt
    13621 tcaaaaccac agtcagctgc tactacatga ttttttgaca aggcctgagg aaatattgtc
    13681 agaggaacgt atggctgatt ggcaaaaatc gctaggcagt gctcaaacga cagtgaaatt
    13741 ctcactgacg aatgatgaat tggagaagtt aatcagtaaa caaaaattag aaaatactag
    13801 tgggctattt attcatccgg cgattgacgc tactttttcg tttttatatt ggtacagcga
    13861 tccttacaac catgaccgtt tcatggaccc gggaacggat tctgtaggca ttgctttttc
    13921 taaagaaaat atgttagtct tattgcaaga agaaaacgga gaaagtagtg atagcagtga
    13981 tcgttaacga agagctgttt caactggagg atcaatgcct ccaagtcgct gaaatgataa
    14041 aaaagagtaa aacgatggct tcttatcttg aacataaaca gtcaatggaa gaatctgcaa
    14101 aagtttgcca gttgaaagaa gcgttcttgt ctaagaaaga agcatttgaa aatgtagcgg
    14161 catatggtga gtatgcacct gattatcgtg aaaaaaaacg agctgttcga aaagcaaaaa
    14221 gacagcttga tatggatgag catgttgcag ctttccgata tagtgaaaca cagctgcaaa
    14281 gtctgttgga tcaaattgtc caagtacttg ccgaagaagt ttctaatgaa atcaaagtag
    14341 atgcaggtag cccgtttttt gaaacgaaaa aacactttgg atgcggaggt aattgtcatg
    14401 caattagaca atagtgaatt tgaaataaca aaacgacgcg ggctgatcgt atgggtctac
    14461 agcttaaaac aattaaagaa tctgaaaaag ttcggcttgt tgcattatgt ctcaagaaga
    14521 atgaaatatg tcgtgcttta cttaaatgaa gagacattgg aagaaacaga agaacgaatc
    14581 cgtaaattac attttgttcg aaacgtagaa cgttcttacc gaccggatat cgaaatgaat
    14641 tttgccgaaa aaataggaaa caaaacagta ttaaaagacg aaggtttcga aattgaagag
    14701 ctaaatacag aaatccgatt agctgaacat ctttaaaaat ctcttatgag cagtttttaa
    14761 ataaaaaata acttggataa cgatcgattt ttgatcattg tccaagtatt tttttggtat
    14821 actagtacca gtaccatttc taaggagtga gtagatgcgg ataatatcag gaaattatgg
    14881 cgggcgccgt ttaaaaagtt tagcaggggc gaacaccaga ccaactacag ataaagtaaa
    14941 agaatccata ttcaatatga ttggaccata ttttgatgga gagacagtat tggatctgtt
    15001 tgcaggaagc ggtggtttag ctatcgaagc agtatctaga ggctgcagtc atgcggtatg
    15061 cgtagacaaa aattaccaag cgctaaaaat catcaaagaa aacatcgaaa ttacgaaaga
    15121 accagagaaa tttaccacaa taaaacttga tgcggacaaa gcaatcgaac ggctagcagc
    15181 ggagaaacaa caattcgact acttgtttct tgatccgcca tatgcaaaac aaaaaataat
    15241 cgatcaaatc cataaaatgg aagaactggg acttttttct aaaaccgcag ttatcgtatg
    15301 cgaaacggat aaaacagtcg aattgccaga aactgtggct ggattccatc aaataagaaa
    15361 acagatttat ggcataacgg ccgtaactat ctatagaaaa gagggaaatc aatgaaacgt
    15421 gcattattcc caggaagttt tgatcctttt acaaaaggtc acttagatac ggtggaacgt
    15481 gcggctaaat tattcgatga ggtagtaatt ggtgttttta tcaatacttc aaagaaaagt
    15541 ttgtttcccc cagaagaaag aatgacattg atcacaaaag ctgtttctca tcttcctaat
    15601 gtaaaagtca tgcatcaaga aaatcaattg acggtagaaa cagcaaaaga gattggtgca
    15661 gatgcgttga tcagaggcat acgaagtatc aaagactttg aatatgaacg agagattgct
    15721 cagatgaatc atcatctata tgatgaattg gaaactgtct tcttattagc aaaaccagaa
    15781 tatagtcacg tgagttccag tattttaaaa gaagtactgc actttggcgg agatgtgagc
    15841 agctacttac cgccagtgat caacgaagct ttagctggaa agcgtgaatc aaatgaaagc
    15901 taaacaatgg ttgaaaacag tactgattat catatttgga atgttgatca ttggatttgt
    15961 agtagttccc ttgccgtatt atgtagaatc accgggagcc acgatcgatc tgaaagaact
    16021 aattacggtc aatgataagg aagataaagg ttctgggtct ttctctctta cctctgttgg
    16081 tatcaggcaa gctacaggtt tcttagcttt aaaagctaaa atgacccctt ttgaagaatt
    16141 gatcagtgaa gaagaattga ctggtggggc gacaaatgaa gaatataatc aaatgcaaca
    16201 gtattatatg gattcttccc aaaatgcagc aatcgaacaa gcgttaaaac ttgcagacaa
    16261 gccttataaa atggaattca aaggcgtata tgtcatgagt gtagagaaaa catcgaattt
    16321 ctttggcaag ctttcagttg gagatacagt aacaaaagta gacgggaaaa gctttcaaag
    16381 tacagaagca tttatggatt atgtaaaaag ccaaaaagtt ggacaaacaa tcgaaatcag
    16441 ttatttgcat aatggtgaag aaaaaacagc ttctggtgat ctgatcgagt taccaacaga
    16501 taaaaaggca ggaataggta tcacgcttac tgaccatacc gagatcgaat cagatacaga
    16561 tgttcgtatt aattctggct ctatcggtgg gccatcagcg ggattgatgt tcactttaga
    16621 aatctatgaa caagtcactg gtaaaaactt gcgacatggt aagcaaattg caggaactgg
    16681 aacgatcaac agtgaaggag aagttggccg aatcggagga atcgataaaa aagtggcaag
    16741 tgcggataaa gctggcgtag agattttctt tgcaccagat gatacgattt cagacgatgt
    16801 taagaaagaa tatcctgaaa taaaaaccaa ctacgaagaa gcaaaagctg ccgctaaaaa
    16861 attgaattcc tcaatgaaaa tcgtaccagt aaaaacagta caagaagcgc ttgactatct
    16921 agagaaaatg aaatgaaact aaataattaa agaggggttg tgacacgagt tctgtcacaa
    16981 cccctctttt tcgtcaaaaa tcttcacgat aaaaataaaa acaaaagaaa aaattgacgt
    17041 aattagatgt tgaagggacg attttgccag agctcactgt ttcttcaatt ttaaatgaaa
    17101 ggagtaatga atgattttta ctggtcattc tttgaaaaaa gaacaatgat agaaaaaatc
    17161 agcaagaaaa tactagcttc acccaaattg atcatttgga tgtctatgat agttcttatc
    17221 ttttgtatcg caagtggttt tttattatca aatttgctat tttatagaga aacagaagag
    17281 actgctgcaa aagaaatact ttcttcgttt agttccagtg gagaagatcc atcagctgaa
    17341 ggaaacgatg tagaagagga tgctcgtcca aaggtcatgt acaccgatat caaaggaagt
    17401 gtgaaggagc ctggtatcta ttccttttct tcagaagaac gggtctatga tgtactaaag
    17461 cgtgcaggtg gattattaga agaagcggat agcgatcgaa tcaacttttc tgcgaagata
    17521 gaagatcagc aagtcctata tatccctgct gtaggtgaag agctgccaga acatcttgat
    17581 cagttggcat cctcggaagg aaaacagcct acagcagatt ccgagcctcc caaaataaat
    17641 atcaatacag ccactccatc agaacttcag cagattcctg ggatcggatc agtcaaagcg
    17701 caagaaatca ttcgatttag agaagaaaac ggatccttcc agaaagtgga agacctgcag
    17761 gagatttctg gtatcggtga aaagacagtt gaaaaactaa aaaacttcgt tacaattaaa
    17821 tagaatgatt caaaatcgac tggcacgagc aataaatgga cgctaatgga tactaagaat
    17881 aatccaattc taagagcttg gcaggacgag gaggtagtat ttttggatag gaaatagctt
    17941 gattgttcgc aaagaaacat taaaaaaacc aatgctgaat gtctatctcc aaaataaaat
    18001 atctgggatt catattatga atacggctgt cagcggcaat aacagtcaag ctctacgaga
    18061 acgctttgcc aaagatgtac ttagctatac agcagataaa gtatttattc tcattgggac
    18121 gaatgatcta gcagagcata aacaactttc taaagaaacg taccaaaaaa tctgcagtgg
    18181 atgatagttc agctgaaaaa agactatagt tctgatcatg ctttctttat cacgccacca
    18241 gcagtcgatg agacaaaaca aaaatatcgg aataacaagt tgatcaaaga atatatctct
    18301 gttctcacag aagtagcaaa acgccatgat tgtgaagtat cgatttttat acggaatttc
    18361 ttgaacaaat ggattcgaag aatttttata atgggctaat ggatgacgga cttcatttcg
    18421 gcagtgaagg gtaggatctt ttgtcagaca ggatgattcg ttatatttaa agaatatttt
    18481 gtttaagcaa tgagtacttt ttaatcaact tgaaaaaacg gaggaatata aaacatgtta
    18541 gaaaaatctt caaaagcatg cgatacgaat aaagaaaaag ttactgataa gtcacataat
    18601 gaacgcattc cttgggacca gtactttatg gctcaggcag tactgttatc tttacgtagt
    18661 acgtgtacac gtttagaagt aggagcgaca ctcgttcgag aaaaaaggat cattgctggc
    18721 ggctataatg gagcagtcag tggagatgtc cactgcatag atgaagggtg ttacgtcgtg
    18781 gatggacact gcttgcgaac gatccatgca gagatgaatg cactcctaca gtgtgcaaaa
    18841 cttggtatcc cgacggaagg ttcagaaatc tatgtcacac attttccatg tttggcctgt
    18901 acaaaggctt tgttgcaagc tggtgtgaaa gggatcaatt atctccatga ctatcgaaat
    18961 gatccttatg cccaagcgtt gatcgaacaa ttaggtgtat ctgtacacca agttgcttta
    19021 gactcacagc atttttcaaa acttcaaaat gaattaacag gaaaacatgt ctagcgtttt
    19081 agaaaggcat gttcgaaatc ggttgatttt tccggcaatt acgtcgatga ttatctgttt
    19141 gttgtattac actgacaatt ggggttatcg tttgcttctt gccggaattt ttttatggtt
    19201 ttcgctaaaa gaaggacgtt ttatcgcgta cttgtgtatt ttgtgtagca taacggtatc
    19261 catttcttat aggctacaag agtattcatt tttagaggaa aaaacaacat ctgcgcaaat
    19321 tactgtattt acagatacga ttcgtgcaaa tggtaatttt ttgacaatgg aaggaaggtt
    19381 atcagagaat aaacaaaagc tccagctttc ttatcaagta aacacagaag cagaattgaa
    19441 aacatggctt aacttccgag gaaagggaat agaattgact gctgaaggcg agttcatctc
    19501 tccagcaaaa aagcggaatc tttataattt tgaccaagaa gcttacttca ggaaccatag
    19561 aatttctgga cggttccaaa ttcaaaagat tgaacagatc accatgcaaa atcactggcg
    19621 aaactggctt cagagaaaaa gaggatcttt tatctccttt gtccaatctg aatttccgca
    19681 aaaaacaagt gtatatatta attctttatt atggggctat aaagatgcag gattcagaga
    19741 accagaagaa atttttaggg agagtggttt gctgcatctg ttcagtctat cgggtctaca
    19801 catccaattt tatttagggt ggctgtatta tttgtttcga cgtatcggat ggccactaca
    19861 cgtcagtatt attccgttga gtctactaac tatctgttat gtttctattg caggaagttc
    19921 tatttctgtt ttgcgtgcta gtttgctgtt tttattgcga ttgctagtca aattgctgaa
    19981 taagcattat tccaccatgg acttatttgc agttgtcttt tggcttcttt tactatttga
    20041 tcctcgattt ctttttcatg cgggtggaca gcttagtttt ttcatgagtt ttttgtttat
    20101 cctgatttct tttgatggag attggttgaa aaaaacggcc tctcacgtcc tgtttactat
    20161 gatcacgatg ccgttgattg tatggcattt ttatgagtgg cctattttag gtagtctttt
    20221 tacattactg attgcaccgg tattcaagtt tctttttctt cctggtgtgt tatttctcac
    20281 actcttcaat cgctggctgc cggaaacttt acttttgctg atagaagagg gattaatctt
    20341 atttgagcga ataatcgatt tttcttcagg gtcgtctctc attataggac gtttgcccct
    20401 tgtgctatct gggatgtata ttttcggatt actgatttgt atggataggt tgaaagaaca
    20461 acctgtgaaa cacttgtttt atgttggtct tttttctttt atttttttga ctttgccatt
    20521 tttacgcttt tcttcaacga tcgcttttat cgatgtcggt caaggagaca gtatcttttt
    20581 gcaaagtcct tttcgaaaag aaacgatttt gatcgatact ggaggtcagt tacactttga
    20641 aagagaaaag tgggcgcaag gtatgatacg tcctcctgct gaaagaaata tcgttccata
    20701 tctaaaaggt caggggataa gtgtaatcga taaactcatc ttgacacacg acgatacgga
    20761 tcatgtggga gaattaccca cgttatctca gcattttact atcaaaaaaa tttatatcgg
    20821 ttggggcgct ggacgaaatg agccattaca aaggcattta tctgaagctc aaaaaaatgg
    20881 tactgagatc attgaaatca aacatgggga caggatcagc ggttattatg atctttatgt
    20941 attgactcct tttgaaaagg gagagggaag aaatgaagat tcgattggtc tatggatgga
    21001 atataacaat aggcgctttt tatttttagg agatttgaat caagcaatgg aaaaacaatt
    21061 gcttttgatt tatcctaatc tgaaagccga tgtagtcaaa ttaggtcatc acggtagccg
    21121 tacgtcaagt aacacagatt ttctttccca tattgaagca aaacatggga ttatatcctg
    21181 cggcgtaaat aatcgttatg gtcacccgca cagcgaagta ttggagacac tagaagaaaa
    21241 tcagataaaa acatggcgaa cggatcaaca aggaatgatc acctatcgct ggcatccagt
    21301 ttttcatcct catgggctag tggaaacaat gatagactag taattctcat ctgctcatgg
    21361 taggataatt tttgaaagtg gtgagtaatt tgagtataca agcagagtta caaaaaatac
    21421 gtaaagaaaa acttgcatct tgttacttga ttttaggaac agaaaagttt ctccaagatc
    21481 aagttcggac agaaattgtc aaaaaaatcc aattagaggg cgaagatgac ttaaattttt
    21541 taagttttga catggaaaat gcaagtttag atgaggtagt agctgaagca gagacgttgc
    21601 cgtttttcgg agatcaacgg ttagtattcg tagagaatcc ttatttttta acaggtgaaa
    21661 aagtaaacaa tggaatcgaa caaaatactg atttattgac ggcttatttg aaagaaccat
    21721 tagaatcgac tgtattagta ttctttgcgc catatgaaaa gttggatgaa cggaaaaaag
    21781 taacgaaaca attgaaaaaa acagcaatta tcatcaatgt ccaacagttg aatgaaaaag
    21841 aagtacgtca atatctgatg aataccttag agaattcctc aatcaaaatg gaacgaagtg
    21901 caattgattt attcttgagg ttgaccgact tagatttatc caaaatgatg agagagttac
    21961 agaaattggt cctttatgga caaaatcaac agcaaatcac ggtaagagaa gtagaagaat
    22021 tagttcctaa aacgttagaa cataatattt ttgacatgac ccaatatatt ttaaaaggga
    22081 agacggaaca agctttgcgt ttatacgaag atttagttat gcaaggggaa gaaacaatca
    22141 aaattaatgc gattttgctt tctcaattac gtttattttt acagacaaaa tttcttgtaa
    22201 agattggtta tcagcaggca aatattgctg aaacattgaa aatccatcca tatcgtgtaa
    22261 aacttgccat gcaggaagta aaaaaattcg atgaacattt gctggtacag ttgtttgatc
    22321 aattagttga gatggattat caaatcaaaa cgggacaaat cgaaaaagaa ttaagttttc
    22381 aactattcgt tttgcgcaca gggcagttgt taagaaatcg ataagaagaa agacgagggc
    22441 aaagcatgcg ggaaggtcgt ttgtttttgt cctttttttg acaaataaaa aaatcggccg
    22501 aagccgattc ttttatttag cgattttttt gcttaaacga gatttgtcgc ggttagcttt
    22561 gtttttgtgg attagacctt ttgattcagc catatcaata gctttaacag cttctttata
    22621 taacgcatct acgttgtcag cacctgaagc tacagcatct tcaaattttt tgattgcagt
    22681 acgcatagcg cttgtttgag atgaattttt cacattagcg ttttcgcttg tacgaacacg
    22741 tttgattgca gattcaatgt ttggcattag tttcacctcc gataacttaa gttcttacgc
    22801 gtgttaccgc ataattcaac attcattatt atacctaaag gcagcgtgct ttgcaatatg
    22861 aacatgacaa gtttttttcc ttaacagtct tttattagga ttttttttca gtaaaaacgg
    22921 atagtacaag ctgaaaaaaa tcaaaaagac gctattgtgg gaggcaatag cgtcaaacca
    22981 aactagattt ttatttatct atttaaacaa agtttgaatg ggaatgtttg gtactaagtt
    23041 attatataac aaagagaacc gtttgcaaag ttttttttga aaagggatac gattccctgt
    23101 tgttctttgt ttttctatta agaaactgca gttattttat aaccagtatc ctttgatcag
    23161 taaaggctat tctggtgtac cgattatttt aatgtattca tcgatatttt ttatcaacat
    23221 tttttttatg accaactggt tccgacggtt ccatttgcca cttacttcca gcacatattt
    23281 atttaggggc aaacgtaaga tatattttgc caaatagcga tctttaagca ggccattgat
    23341 cacacggtcc tcaagctgca agttgatccc agtcagcatc attggctgtt cttgtaaaac
    23401 gtacgtatca attaaaagac cttcaaaagt ttccacaagc gtcttccttt cttttcaaag
    23461 taacctgaaa acaggcacta attcttccat tttgatattc gttgaagtgg atgcgatcat
    23521 tctttctttt gtccactgta atctagtata acaaaaaaga gcagaagagc caaaaagaaa
    23581 aaagagcatc gaattctata ggaagtctca ttggcacggc ctaaattatt acaaaacatt
    23641 gattaaaaaa agcccctgca tcgcaggagc atcccctata tcgttttaat aggtcaatca
    23701 aaaagcagta tcaaacacat tttgtatcaa atcaggaaat aatagataag ctaagcccag
    23761 aatcaaaagt accgctagaa gaaaccagcc gattgttcct atgaaatact ttaatttttc
    23821 gaacattgta tcacctcgtt gtcagtatat cacggatcag taaattgggg gtgttaagaa
    23881 tctcctaaaa tagacaaaat ttgttctatt ttcctaaagc aaatacttgt aagatacagt
    23941 aagtgatacc agaagcaatg accggtccgg cggcgattcc tcttaagaag acaacaccta
    24001 aaatcgtgcc gaaaacaagt gcaacagtga tttgtggatc agaagcaatc aatcctacac
    24061 ccttggaaga taagacagcc actagcccac cgcaaaaaac agctacccag ccaatagggg
    24121 atttaaaggc ttctaataga tcacgtagac cgatttctcc tgttgcgata gggattagaa
    24181 tagccgctgt gatgatcgtc accccaatat tgattccttt gccttgaagc caagggaaaa
    24241 aggaacggga ggctggtatg agcttcataa tcaaaacaaa agctgccgct atcatcagac
    24301 tttgattttt agctaaaatt gctacaagta aaataattcc taaaaaaagc caactttcca
    24361 tgaaatatat tcctcacttt cttcgaaaca atcataacat gtttttagaa agttacaaaa
    24421 gtaggaattc atccttcaag acctattcat aagctgtttt tttcataaaa taaacaaaat
    24481 cataaaaaaa cactttgctt atttgacaga agacagccgc gctttgtata gtggacaaga
    24541 cttacatttt tttgaagaat cagaaagatc aggtaaaggt cttagtaaac gcaagccatt
    24601 cagaataacc aatattgtgc ttccttcgtg tcctacaact ccaagaggta gatttaaaaa
    24661 ttgcaggaag ttagaagcaa tcaacaagag aataacaaga atcgaaaaaa taatattttg
    24721 tttgatgatc cgccgcattt ttaaagatag ccgatgactg tagacaaatt tatttaagtc
    24781 gcttttcatt aagacgatgt ctgcgatatc catagcggca tctgtccctt gccccatagc
    24841 gacacctaaa gaagcggctg ctaaagcagg cgcatcattg actccatcac caaccatcgc
    24901 atttacttgg taaagttcat tctctttttt gactagttgt gttttttctt ccggagtaca
    24961 gcttgcatag taatgttcaa tccctacttg ttcagcaatg gcctttgctg tgccagaatg
    25021 gtcgccggtt atcatacttg tatggatgtt ttgggattta aagtaggaaa ttacttgttg
    25081 ggtatttgct tttggaatat ctagcagacc taaaacagca attaactgct gatctttaga
    25141 aagataaatc acggttttgc cttgattttc caaacgttcg atcatttccg caatctcttt
    25201 gctgattatc atcgtctcag gatcatatgc gtgcttgcca actttccatt gcgcacctaa
    25261 ataggtagtt tgtaatccaa aaccagtaat ttcttctatt ggtaagtatt ggatttcttc
    25321 aggtattgtg caatcgaaat attgcaaaat cgcatgagca agtggatgcg tcgttttttg
    25381 ttccatagca acaagaagtt gttgtgccaa atccttttca tcaaagaaaa agctgtcagt
    25441 tacaactggt tttcctttag tgagcgttcc tgttttatca aaggcaatcg cttttaattc
    25501 agaaagcttt tctaaatgga taccgccttt gattaaaatc ccattttttg cagaatttga
    25561 aagagcagct agagaagctg gtgtagcaga tgcgacaagc gcacaaggag aagccacaac
    25621 taataatacc attcctcgat aaaagctttc atcccaactc caacctagga aaaagtgggg
    25681 gagaaggatc attagaggaa cagcaagcaa aatcaatttt acataattat tttcgattcg
    25741 ttcgataaat gaagctgttt gagttggcgt attctgcgct tcttctacta attggataat
    25801 cttagcaaag acagtttcgg aactcgtttt tgttactcga atcgtgatgg gatttccttg
    25861 attcagcgtt cctgcataca tctcatcgcc taaatatttt tctacaggca cagattcacc
    25921 gcttaatgca gactcatcga tcgttgcctg tgtgctttct aaaaagccat ctatcggaac
    25981 agctgctcct ttagcgacaa ataccaagtt atccaccttt agttgagaaa catctacttc
    26041 ttgcatttgt ccattttctt ttaataattg ggctttttgt ggttgaagat tcatcaaagc
    26101 agtaatttct ttttgacttt tattagttgt gtattcctct aatgcaccgc ttaaacaaaa
    26161 gatgaatgtc aacattgctc cttcaaagta attaccgatc aaacaggcac caatagcagc
    26221 taaagccatc aataaatcca cattcagtgt ccgatcattc cacaattctt tcaagccttc
    26281 cgatgtttgt ttatatccac cgatgataat ggcactgata taaaaaagtg gggtgatggt
    26341 aagagagaat cggtcgaaga taaaaccgaa gatcataaat aaaaggcagc cgattgttgc
    26401 tgcaaaagct tttttctgat tagtcatcgt tattagacct ccttgtcaaa acaaggatag
    26461 cataataaaa atgtaattga taataataac agctaaatga gaacgataat ggttatcatt
    26521 tggtgattaa gcttgatgtt gtttttatta tttataatga ttattattaa agaaaataaa
    26581 aaaccagaac atttctcaaa taagagaagt gttctggttt tttctacatt gcaataaacc
    26641 aataaccaat caaaatgata ccaaggataa tacgatacca gccaaaagcg gtaaagtcgt
    26701 ttttcttcaa atagcttagt aagaatttga tagctaagac ggaaaccaca aaagatacga
    26761 atgttcctac aagaagaaca acagtttctt ccattttgaa tgaattccct tcagctaaat
    26821 atttgacgat cttcaagccg cttgcgccaa acatgacagg aatccctaag aaaaatgaaa
    26881 actctgtagc gacaaaacgc gaagcaccaa tcaagataga tcctaggatc gttgcgccag
    26941 aacgggatgt tccgggaaca agtgccaaga cttggaataa cccaacaaga agagctgctt
    27001 ggtacgtaaa gtcattcaga gaagtccaac gaggtgtttt gtttttgttg cgtttttcga
    27061 caataataaa ggcaataccg taaacgatca aaacaatggc aactggtaag aacttgtgga
    27121 aatttgcttc taaccaatca tccaaaggca aaccaatgat gatggctggt atgcaagcaa
    27181 cgatcacttt aaaccaaagt gtccacgtat cttttttttc taccgttgat ttacttggag
    27241 aaaatgggtt taacttgtga aaataaagaa cgacgacagc caagatcgcc cctaattgga
    27301 taacgacatt gaacatcgac ataaattgtg aactggcatc cagtttgatg aattcatctg
    27361 ctaggatcaa atgaccagta ctactgatgg gcagccattc cgttattcct tcaataatac
    27421 cgagaatcac tgctttgata atatttgcaa aaaacataaa ttccttcctt cccaattaag
    27481 atacatctta tagtataccg ttattttttg agaaacccaa tctgtttttt aatattaaga
    27541 aaaacttgag aaataaagca gataagtaca cgaagagaaa aaagaagaca aagccctcgt
    27601 tcagactttg ccttttatga ttctctggta aaaattaaaa tatccccatt atagaaacga
    27661 gtcgcgacta tgtgttttcc cgttatcgat ataagacgta tcattgatgc cgtggataga
    27721 aaatcgaccg tttgcataag tgacctttgt tacgctgcca tttaaaagcc cagcacgaac
    27781 aggctgttta ggatcgatca gattaagcaa aaaggcgatc gtcaaaccat gagatacgac
    27841 taaaacattt ccaccaccat ttttttcgca gtgatgggcg atatcttcaa atcctgtcca
    27901 tacacggtct cgcaatgttt cataagtttc cgcccaccca gcggtatcta agttgtatac
    27961 agcattagca atttgtttaa aagaaacttc tgtggtaaac atttcatcat atgttttaaa
    28021 attcaataca cgagggatca caccccacat ttccatgtca tatccacctt caagagaccc
    28081 gaaacaccat tctctaatcc ttttttcaat aaaataagga atttcttttc ccttagaatg
    28141 ttctcctaga ataatacggg cagtttcgat tgcacgacca ctgtcactag aataagcaaa
    28201 tgaaaagtcg acatttttta acccgcgacc taaataatga atgccttctt gtccttgctt
    28261 tgtgaggggt gtatcacacc agccttgtac tcgttcaatt gtattgaaca tcgtttttcc
    28321 gtgtcgtacg atataaagtg tagtttctgt cattttattc tcctcctaag tcgttttaac
    28381 gattgaaaaa aggatttgtc cttttttcct gttcaatcgt cgttgcatcg ccatgtcctg
    28441 gatagactgc aaattcatca ggtaatacaa acagctgggt ccgaatacta tgaagtaatt
    28501 gttctaaatt ccctgtatac agatcggttc taccgatact tcctctaaac agggcgtcgc
    28561 cagaaacgac aaaatcatca aaaataaagc tgacgcttcc tatagaatgc cctggggtag
    28621 ggacgacgcg aaaagacatg tttcctaaag tataagtttt catttcaaat tcatattctg
    28681 caggcgagac aataacatca gcaatatcat catgtctacc gagtccagaa agattcaaaa
    28741 tcggatcacc tagccatttt tgctctagtg ggctgacata aactgggatt tgataatacg
    28801 cgcgtaaagg ttccactgca ccgatatgat cgtagtgagt atgggtaagc aaaatcgcta
    28861 ccggctgttg gtttgttttt ttgatttctt gtttgattcg ttccgcatct tctccagggt
    28921 caatgatcaa aagtgcttct tcgttgtaga ccaaataaca gttttcttca atcattcctg
    28981 tttttaatct ttcgatatgc atgtgcattc ctccttgata gccaaaactt ctttcatcca
    29041 ttagtataac gcattcattg ctaggaaaca aaaacaggta cttatttctc tttacttatc
    29101 tgaattatca gactatatga aaagtatttg gatattctaa agagaaggaa agtaagtttt
    29161 catagcattt taatatgtcc ttgttacatt agattcatcc aaaaatccaa attctatatc
    29221 ctatatccct gcctaatcag cagggtgttt ttttatgttt ggaaagagag ctctttttgc
    29281 taaactaggt tttttcaggt aatcttagag agaaagaggt ggtggaaatg atcaaacagt
    29341 caaaaatatc tgtgcggcac ttagtagaat ttattttgcg acgtggaagt atcgacaatc
    29401 gtaaaaaaag taaccatact gcattagaag gagcgagaat ccaccgcaag ctccaaaaag
    29461 atgcgggaga aaactatgaa aaagaagtct ttttaaaaac aacagttcaa ttagatgaat
    29521 attacctgat cgttgaaggc cgtgcagacg gtattttcaa aagagacggt atttattata
    29581 tagatgaaat caaaacctcc gaaccacgat ttgaagattt agaaccagaa caagtggaac
    29641 ttttctttca tcaagcaagg gtgtatgcct atatctatag tcaagaacat gatttacaag
    29701 aaataaatct gcaattgact tacttccaga cggcagaaga agtgatcacg agaaaggttg
    29761 aacatcagac aagagagcag ttagaaactt tttttaaaaa gctgactgaa gattataaag
    29821 aatggcttgt ttttcaagaa aactggcgca ctgtacgcaa tgcctctttg atggctttga
    29881 aattccccca tgatgagtat aggaaaggtc agcgtgaact agcggtagct gcttataaaa
    29941 cgatccgtac gaaacagaaa ttgtttgtag aagcacctac cggaacagga aaaacaatct
    30001 ctacgttatt ccccgctttg aaagctgtag gggaagaaga gggagaaaag atcttttatc
    30061 taacggctaa aacaataact agacaagtag ctgaagatgc tatgacagca ttaaaagata
    30121 caggagctga agtaaaaagt gtcactttga cggcgaaaga caagatctgc tttttagatg
    30181 agacgacctg taatccagat cagtgcccat atgccaatgg ttattacaat cggattaatg
    30241 aaggtttatg ggatcttttg aatcatgaga atcagatcac tcgtgaagtc atcgaaactt
    30301 atgcaagaaa gcatacactt tgtcctttcg aactatcatt agatgtcagt atctggtgtg
    30361 acgtaatcat tggggattac aattatttat ttgatccaac tgtttattta agacgttttt
    30421 ttgaagatga aaaaaacgag gactatctgt ttttgattga cgaagcacat aatttggtga
    30481 atcgttcccg agagatgtat tcggcagaac tatcttatga aaaaacgaaa cgaagtaagg
    30541 aagctatacc aaaggaattc aaaaaacttc atcgccgttt caacaaacta ttaaaagaat
    30601 ttgattcgat ccgagaaata gcaaaagaag atcattggga ttatcatcat caaaaagcac
    30661 cggctgaatc tttagtaaag gcaggttatc aattaagcga aaaaattaaa gaatggctgg
    30721 cagaatttcc tgagcaccca tcacaagaac aattgcttcc ttattatttt gatttgcttc
    30781 attttttgaa ggtcagtgaa ttttatgatg atcactacga aacaacagtc gaaaaaacgt
    30841 atcgcgatct gatagtaaaa gagttttgta ttgatccaag cttgtttctt gagcagtcgt
    30901 tggataaagg aaaaagcagt attctttttt ctgctagttt ttcaccactc tcttattatc
    30961 aggaaacact ggggggacaa aaaagtctgg cttacaaact gccgagtcct ttcccagaag
    31021 gaaaccagca agttttcatc gcaaattacc tagagacgac ttatcgaaaa agggaacaca
    31081 gtctggcaaa attagtagag acgattcatg cttttgctga tggaaaggtc gggaattatt
    31141 tcgttttctt tccttcttat caatatttag atcttgcggt ggaagcattc agacagcaat
    31201 atcccgacag caatgtgcta atccaagaaa cggacatgaa tgaggaagaa cgcgaacgat
    31261 ttttaacaaa atttcaaaca aatcccgctg aaacattgat tggattttgc gtacttggcg
    31321 ggattttttc agaaggaatc gatttgagag gggaccgatt gatcggcagt atgatcgtag
    31381 gtgtaggttt gccgcagatg aatcatgagc aggaactgat caaatcatat tatgatgaga
    31441 aggaacacct tggatttgct tacgcttatc agcttcctgg aatgaacaaa gtcttgcaag
    31501 ctggtggtcg agtgattcgt ggcatggcgg atcaaggaat cgttgtattg gcagatcaac
    31561 gattttctag tttttcttat cgacgtttat tcccacaaca ttggcaaaca gcaagagaag
    31621 tacgaagtgt tggggaattg gaagaaggaa tacagcgttt ttggttatca aaagaagcag
    31681 taaatcaaaa aaacgaggaa tgacagacgt cagcctcgtt ttttgattaa cgatagttag
    31741 tgaattgcaa ctcgattggt aagtcaagtt tacgtaataa agcaatcaca gcttgtagat
    31801 catcacggtt cttacctgtc actctaatct gatcttcttg gatttgtgct tttactttca
    31861 gtttttcatt tttgatagct gtagtgattt tcttcgcgtt ttcacgatcg attccgttga
    31921 ccaaatcggc agtttgtcga gctttgccac ctagagcgtg ttctgattcg gaaaaatgga
    31981 tatttttgat tggcacattt cttttgatca gcttaccaaa taatacatct ttgatctgtt
    32041 cgattttgaa atcatcatcg ctcaatacaa ctagattgct gttctctaat ttgatttcta
    32101 ctgtagaatc cttgaagtca aagcgattgg acaattcttt tgttgtttgc tgaatcgcat
    32161 tttttacttc ttctgtattg acttctgata caatgtcgaa gctagcatct tttgccatag
    32221 gaaccctcct gatatacata taaatattta ccatacatct atcttatcat aggattaggg
    32281 cagattctta cctgtttgct aaaattcttc tcatttgagt tcgaagtatt ttattttaat
    32341 agataaactg ttattcttac atttggaata ccaaagtagg ggagaggtgc ttgtgagtaa
    32401 aattatgact gcgtatcata aaaatgaaag attaaagaaa atagtggtta ttttgataac
    32461 cggattgacc gctgcggtcg ctttaaatta ttttttgatt ccagccaatg tcttttctgc
    32521 agggatgaat gggatcgctc aaatcatttc ctcgctttta tatgaatggt ttcatatcaa
    32581 gatagacaca ggaacattta tttttctttt gaatatccct gtgtttgtat tagggtttct
    32641 caaagtagga aaacgagcaa cgatccttag ttttgtgaat gttgtatgtg tatcggtgat
    32701 gacgatgctg cttccagtcg gacagatcac tgataatatt ttgatgaatg ccctagtagg
    32761 cggtgtttta ttaggtcttg gcgtaggatt atctttaaaa atgggcttta caactggtgg
    32821 gatggatatc atctctcttg tactttcaca aacaactgga aaaacagtcg gaaactacat
    32881 gctgattcta aatggtatca ttgtagtcat cgcaggcttc ttctttaact gggaaagtgc
    32941 cttgtatacg attatttcca tttatgcaat gactcaagta attgatgcca tccacacgag
    33001 tcatcaaaaa gtaacagcaa tgatcgttac cgtcaagcca gaagaggtaa cagaagaact
    33061 agcaaaacgg atggtacgtg gaatgacatt actgccgtct gtcggtggct attcaaaaaa
    33121 acaagggaac atgatcatga tggtcatcac ccgctacgaa atgtatgatc ttgatcagat
    33181 cgttcatgaa atcgacgacg atgcatttat caatatttta ccaactcatt cagtatttgg
    33241 ccggtttgca aatgaaaacg aacaaaaaat gtatcgaaca actggcgtat tgccagaaat
    33301 aaaaaatcgt tcacaaaaaa aatgaggaat caggtttatt ttagaataaa tttaatctat
    33361 tacatctaat aagaacattt ttataaattt aaacgagaat cttacttcta aattctcatt
    33421 tacaagcagc taaaaaaaga gtatgataaa taaaaatcgt gttaaggagt gtcgtacgat
    33481 gagcgaagca aaccaagaac ggtctggaca agaaatagaa ctaatcaaag aacgtattct
    33541 tgctgccttg gaaatggtga ttgatcctga attaggaatc gacatcgtca atttaggctt
    33601 gatttatgat atagaattca atcctgaaaa tggagaaaca gtcattaaga tgactctaac
    33661 aactatgggc tgtccattag cagatatttt aacagaatct atccatgacg cattaaaaga
    33721 agtgccagaa gtaacgaaag cagaagtcaa actagtctgg tatccagcat ggacgacaga
    33781 taagatgagc cgttatgcac ggattgcgtt ggggatacga tagaaatctt ggctgactag
    33841 ctatgagaag caaataggaa aaacaaaaaa gccttttatc ctttctagaa gaaaagagat
    33901 aaaaggtttc tttgtttata aaattttgtc tgctatatta taagttaatt aaataaatgt
    33961 gttctattga taaaggacat tcaaatccct ttccttttgg aatccttctt ttttacatca
    34021 gtttgatttt cgtatagtat tctttctcat cttcacgata aatcgcagcc ccattttttt
    34081 gttgtgcttt aagactgcca agattttttt tatttacaga caaaagtgcc tcatcaatgc
    34141 cgattttttt tgcctcttgt agtactaatg ctaatccttg tgtggcatat ccttttttac
    34201 gataattagg ggagatgccg taaccaatat ggccagcgcc gtttcttaat gtttcgttca
    34261 gtttatggcg caaattaaaa attcctacat actcatgttc atcactttct aaaataaaga
    34321 cggttgcggg aacgtaactc tcaggaagat cgattcctaa agacgttttt tcgcattttt
    34381 ttacataatc taaaaattca gcaaatgtat agccataagc attgttgata aatccactct
    34441 catttggtcc aaagctagtt tgtagctgat aagctttctt taaatctgct tcccatagtt
    34501 tgatcagttt catcgtattc acctctttaa gtaaccttat tcatttgttt tctactatag
    34561 cactattgtt gtaaatagcc atgcctattt ttatttattg tgtcatatcg tattaagaat
    34621 catcgaacaa tacaaatatg aattacaata aaaaaattat ttgaagttcg ttcattcgtt
    34681 acttatgatc tctagaagaa agaaaacgtg aattacttca gcgtctagaa ttccagaagg
    34741 atagtaatca acagaagaaa taatcaatat ccaaatgaaa gaagatagct gaatcgagaa
    34801 aaagaggaaa aaagaaatga agaaaaaaat aaaatagtta ctaatcccag agtcgttcgt
    34861 ttaacattga aatcgatcat atggataaaa cagatttttt caccaaccct caatagatga
    34921 tggagttgct cggatgaatt atttgtgtag atggcataag ggagggcgta cagaaatgaa
    34981 aaagaacaaa aatatgttct tgacaaaaaa cacatgtaat cctaaactaa aagatgtgat
    35041 gcggctatgg cggaattggc agacgcgcta gcttcaggcg ctagtgaggg tgacctcgtg
    35101 gaagttcgag tcttcttagc cgcataattt gtttttttat aaagagaagg tacacctgga
    35161 gcgatgagaa agaaaataac atattatcta aaagaatata ggaaaaattt taaacaacgg
    35221 aaccagattc aaataaatca aaaaaaattt gtgtgaaggt gggacagttt aaaacctaat
    35281 agattgattc aaatagtaga tttatagatt ctgatacaag aaatactggc aaacgatagt
    35341 taaggaataa agactaaact taaactcaaa aagaggtcat gcgaaagaat aaatcgcatg
    35401 acctcttact atattttgaa tgtgtttaaa cgttcaaata atgaatctta gtaccaaccg
    35461 tttgcttccc agaatgcttt cgccgcttcc caagaaccat aacgtgaagt aacatattgt
    35521 tctgctactc tttcttggtt tgcagcagag tagtcaccat ttaagtaaga agaatctaat
    35581 tggtaacggc cgatgtaacg tccgttcgtt gctgtgtaag aaccgcttga ttctttttgt
    35641 gcgatccatt cttttgcaga gcttgtactt gctggagtag cagcagtttc tgttacagca
    35701 ggagcaggtt gtgtttcagc aacaggcgct gcttgtgttt ccgtttgaac cgtttcttgt
    35761 acaacaggtt gttcagcttg aacaggttca gcttggactg gtgcttcttg aacggctgct
    35821 tgaggttcag cagctgcttg tgcagagcct tctgttggga ttgttaattg ttgtcctgag
    35881 ta
//
LOCUS       DACGEU010000019        34960 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.019, whole genome shotgun sequence.
ACCESSION   DACGEU010000019 DACGEU010000000
VERSION     DACGEU010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34960)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34960)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34960
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.019"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            153..1859
                     /locus_tag="IXR40_000879"
     CDS             153..1859
                     /locus_tag="IXR40_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin/fibrinogen-binding protein"
                     /protein_id="HAQ4360748.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
     gene            complement(2017..2919)
                     /locus_tag="IXR40_000880"
     CDS             complement(2017..2919)
                     /locus_tag="IXR40_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAQ4360749.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(2916..3620)
                     /locus_tag="IXR40_000881"
     CDS             complement(2916..3620)
                     /locus_tag="IXR40_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HAQ4360750.1"
                     /translation="MKKNMDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKG
                     EETKIEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSE
                     HIINGKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVN
                     PDVFFPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPI
                     QPLNGREIYYFEEFEQ"
     gene            complement(3651..4292)
                     /locus_tag="IXR40_000882"
     CDS             complement(3651..4292)
                     /locus_tag="IXR40_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAQ4360751.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            complement(4330..4644)
                     /locus_tag="IXR40_000883"
     CDS             complement(4330..4644)
                     /locus_tag="IXR40_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360752.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            complement(4632..5261)
                     /locus_tag="IXR40_000884"
     CDS             complement(4632..5261)
                     /locus_tag="IXR40_000884"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HAQ4360753.1"
                     /translation="MNVEQSIAKDLLEIEAVFLNPSNPFTWASGIKSPIYCDNRITMS
                     YPKVRKEIAKGLASKIKEAYPEVQVIAGTATAGIPHAAWVAEILDLPMVYIRSKAKDH
                     GKGNQIEGRIFEGQKMVVIEDLISTGGSVLEAAEAAKREGADILGVAAIFTYELPKGK
                     ANFEKAEIPLMTLTNYSVLIEAALEDRYIDEQELTLLKEWKKDPENWQI"
     gene            complement(5268..5984)
                     /gene="pyrF"
                     /locus_tag="IXR40_000885"
     CDS             complement(5268..5984)
                     /gene="pyrF"
                     /locus_tag="IXR40_000885"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HAQ4360754.1"
                     /translation="MNQLDQRPIIALDFSTRQEVEDFLRFFPKEEKLFVKIGMELFYQ
                     EGPEIVRYLKEAGHNVFLDLKLHDIPNTVEKAMRGLAKLGVDLTCVHAAGGIRMMEAA
                     MRGLEEGTPEGGKRPLLLAITQLTSTSEEEMHADQLIEVSLEKSVIHYASCAKKAGLD
                     GVVSSAWEVEAIKEMAGDEFVCLTPGIRPEGTVAGDQTRVVTPSQAKKIGSTFIVIGR
                     PITQSTNPYKAYQTIQTEWS"
     gene            complement(5981..6913)
                     /locus_tag="IXR40_000886"
     CDS             complement(5981..6913)
                     /locus_tag="IXR40_000886"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HAQ4360755.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            complement(6910..7686)
                     /locus_tag="IXR40_000887"
     CDS             complement(6910..7686)
                     /locus_tag="IXR40_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HAQ4360756.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            complement(7740..10925)
                     /gene="carB"
                     /locus_tag="IXR40_000888"
     CDS             complement(7740..10925)
                     /gene="carB"
                     /locus_tag="IXR40_000888"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HAQ4360757.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            complement(10930..12006)
                     /gene="carA"
                     /locus_tag="IXR40_000889"
     CDS             complement(10930..12006)
                     /gene="carA"
                     /locus_tag="IXR40_000889"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010744830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HAQ4360758.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            complement(12011..13291)
                     /locus_tag="IXR40_000890"
     CDS             complement(12011..13291)
                     /locus_tag="IXR40_000890"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HAQ4360759.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            complement(13310..14236)
                     /locus_tag="IXR40_000891"
     CDS             complement(13310..14236)
                     /locus_tag="IXR40_000891"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HAQ4360760.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            complement(14249..15532)
                     /locus_tag="IXR40_000892"
     CDS             complement(14249..15532)
                     /locus_tag="IXR40_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HAQ4360761.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            complement(15546..16085)
                     /gene="pyrR"
                     /locus_tag="IXR40_000893"
     CDS             complement(15546..16085)
                     /gene="pyrR"
                     /locus_tag="IXR40_000893"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015694870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HAQ4360762.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            complement(16320..17231)
                     /locus_tag="IXR40_000894"
     CDS             complement(16320..17231)
                     /locus_tag="IXR40_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HAQ4360763.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            complement(17228..17692)
                     /locus_tag="IXR40_000895"
     CDS             complement(17228..17692)
                     /locus_tag="IXR40_000895"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HAQ4360764.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            complement(17697..18395)
                     /locus_tag="IXR40_000896"
     CDS             complement(17697..18395)
                     /locus_tag="IXR40_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAQ4360765.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            complement(18382..18768)
                     /locus_tag="IXR40_000897"
     CDS             complement(18382..18768)
                     /locus_tag="IXR40_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360766.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            complement(18915..20585)
                     /locus_tag="IXR40_000898"
     CDS             complement(18915..20585)
                     /locus_tag="IXR40_000898"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HAQ4360767.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            20768..21001
                     /locus_tag="IXR40_000899"
     CDS             20768..21001
                     /locus_tag="IXR40_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock domain-containing protein"
                     /protein_id="HAQ4360768.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            complement(21100..21531)
                     /locus_tag="IXR40_000900"
     CDS             complement(21100..21531)
                     /locus_tag="IXR40_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HAQ4360769.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            21610..22023
                     /locus_tag="IXR40_000901"
     CDS             21610..22023
                     /locus_tag="IXR40_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HAQ4360770.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            complement(22061..23209)
                     /locus_tag="IXR40_000902"
     CDS             complement(22061..23209)
                     /locus_tag="IXR40_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HAQ4360771.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(23331..23927)
                     /locus_tag="IXR40_000903"
     CDS             complement(23331..23927)
                     /locus_tag="IXR40_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAQ4360772.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            complement(24127..26769)
                     /gene="alaS"
                     /locus_tag="IXR40_000904"
     CDS             complement(24127..26769)
                     /gene="alaS"
                     /locus_tag="IXR40_000904"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HAQ4360773.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            27157..27588
                     /locus_tag="IXR40_000905"
     CDS             27157..27588
                     /locus_tag="IXR40_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4360774.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            complement(27633..28982)
                     /locus_tag="IXR40_000906"
     CDS             complement(27633..28982)
                     /locus_tag="IXR40_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HAQ4360775.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(29052..30215)
                     /locus_tag="IXR40_000907"
     CDS             complement(29052..30215)
                     /locus_tag="IXR40_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360776.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            30344..30667
                     /locus_tag="IXR40_000908"
     CDS             30344..30667
                     /locus_tag="IXR40_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360777.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            complement(30850..32199)
                     /locus_tag="IXR40_000909"
     CDS             complement(30850..32199)
                     /locus_tag="IXR40_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAQ4360778.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(32268..33221)
                     /locus_tag="IXR40_000910"
     CDS             complement(32268..33221)
                     /locus_tag="IXR40_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HAQ4360779.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            complement(33323..34513)
                     /locus_tag="IXR40_000911"
     CDS             complement(33323..34513)
                     /locus_tag="IXR40_000911"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HAQ4360780.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
BASE COUNT         9952 a         7640 c         6120 g        11248 t
ORIGIN      
        1 taaaaatttg gatttcaacg atagaaacac tgttttttat gtaattagtc caagattttt
       61 ctagactttt gctttactat tcggccaaat tggtttttct tctttttttc gttataatga
      121 atatacttat gaaaagaaat gaggaatgaa ccatgtcctt tgatggtgta tttacccacg
      181 cgatggtcaa cgaattgcgt gaaacgttac tatctggccg gatctcgaaa atccatcagc
      241 cttatgaaaa tgaaatcgtg ctggtgattc gttcacgcgg caaaaaccat cgattattat
      301 tatctgcgca cccaagttat gctcgtgtac agattaccca aatcgattat cagaatcctg
      361 ataatccgcc taacttcgtg atgatgcttc gaaaatattt ggatggcgct attttagaag
      421 acatcgaaca aatcgaaaat gatcgagtga tccatttcca ctttgctaaa cgaaacgagt
      481 tgggtgatct acaaaatatc atattgatcg ttgaattaat gggacgtcat agtacgatcg
      541 tcttagttaa tcgagaaact ggaaaaatac tggatgcgat caaacacatt ggaagctctc
      601 aaaacactta tcgttctttg cttcctggtg tagaatatgt tgctccgcca aaacaagagg
      661 tcttgaaccc atttagctcc gagaaagaaa aaatctttca gcggctttcc caaactgaac
      721 tagatccaaa agcaatccaa cgtcagtttc agggaatcgg tttcgatatc gctcaagagc
      781 tgaccaaaag attactggaa cgtcctaatg aaaagatggt tgtatgggac gaatttttct
      841 cagccatcag ccatcagcct attcctactt tttacgaaac ggaaaataaa gattttttca
      901 caccgattgc ttatcaggta ttgtccgaac aggcatctgc tgtaacagct tatccaacac
      961 tcagtcaatt attagatagc tattatcacg aaaaagcaga gaaagatcgg gcaaaacaac
     1021 aaggcggaga actgattcga aaaatcgaaa atgaactaaa acgaaataaa aataaattga
     1081 aaaaacgtga acaaacactc aaagaatccg aaaacgctga gaattaccgt agaaatggcg
     1141 aactacttac tacttttctg acacaagtac cacgcggcgc aaaagaagtt gttttaccta
     1201 attattatga agaagatcgg ccaatcaaaa tagcactaga tccggcattg acaccaaatc
     1261 aaaatgcaca gaaatatttc catcgatacc aaaagctgaa gaacgctgtt aagctgattg
     1321 gcgaacaaat ccaagaagcc aaagatgaaa tccaatatct tgaatctgtc ttatctcaac
     1381 tggaaattgc cggcccaatg gatatcgaag caattaaaga agaattgact tcagaaggat
     1441 acctgaaaaa gaagaactta aaaaaacaaa aacgtaagaa accatctcag cctgatcaat
     1501 acttttcttc tgacggaacg ctcattcttg ttggtaaaaa caatcttcaa aatgaccagc
     1561 tgacaatgaa gacagctaaa aaaaccgact attggcttca tgcaaaaaat atacccggtt
     1621 cgcacgtcat cattaaaagt gacaagccct cagatgaaac aattacagaa gctgccgagt
     1681 tagctgccta tttttcaaaa taccgatact ctgcccaagt gccggttgat cttgtacagg
     1741 taaagcatat ccgaaaacca aatggcgcca agcctggtta tgttatttat gaaaaccaaa
     1801 agacgattat cgtgacacca gaagaagaaa aaattacagc tatgaaacaa aacaggtaat
     1861 caatgagtgt ttctagaatc atatttgcgt actttcccac aacagcaatt agttataaat
     1921 tgtttgctac aaaaagagga gttgtgacaa aattctgtca caacccctct tttttgatca
     1981 acggtgttca ataaacagcg ttctcatctg cttttcttag ctctgctggt ccagtaaccg
     2041 agtaagctct ttgataaatc tttgagcgat ttcactgagc ggacgtttcg ccgaataaat
     2101 gatataaaat tcatttagtt cgccttctgc caaagggatt aaccgcaagt gctcgcgaat
     2161 ccctccaatc acaataccag atcctgaagc gtaagcatca gtttcaagaa cgatattcat
     2221 caaagtacct cgatcactcg tataaatcac tgtttcttga tcagggatct cgataaggtc
     2281 ttcataaaaa tacgggaaat tatttccatc ctgtgtaaaa cgaacttgag gataagataa
     2341 caattcttct ttggtgatct ctgcgtgttc agctaatgga tgtccttgcc ttaaaaaaat
     2401 atgcgttttg aattttccaa tgctgcggcc acttagctct ccttgttgta aatatcttct
     2461 gataccagct tgattatgct cattcatata aataatgccg atctcactgt gctgctcttt
     2521 gacttcttcg atcactctcg ctgttgtcgt ctccatgatc cgaaattgtt tgatctcgtc
     2581 tttgaattcc tcgagtagct gtgcggtcaa aggacctaag aaatcataat gctgggcagc
     2641 gatcgaaaaa ttgtctctct tttcactcgt tagatagtga gtttctaatg tatcaagctg
     2701 gaccaatatt ttctcggcac gatttaagaa gtcttgccct tcttctgtta aatatgcccc
     2761 tcgattcgtt cgagtaaaca gcgtgatccc taactcggtt tctaattctt tgataccagc
     2821 tgaaagactt ggctgggaga caaacatttt ctttgccgct tctctgaaac taccattgtt
     2881 tgctacagcg accacgtatt tcatctgctg aatattcatt gctcaaactc ctcgaaataa
     2941 taaatttctc ttccattcaa gggctggatt ggtcggttgt tcggtcgagc atactgacca
     3001 tcgaagggga gaagaaactc ttggttcagt tttcctacat gatccattac aaaccattgg
     3061 attggcccgc tggtaggcgg agttgtcaat gagccaatat aatggaaatg gcttttttgc
     3121 tccggaaaga acacatccgg atttacccaa tgctcatgtt tttctaagtt ccaactttcc
     3181 ccattttctt gattatacag ccaaccttcc tgtaccatta gctggtacat gacacccaca
     3241 actagattct cttttttgct gttcatatga acaaaatgaa attcaatatc ttcctgtttt
     3301 ccgttgatga tatgttcaga aggcaagtgg aaatgaatat ctgtcaaata atagcgttct
     3361 ttcttgaact ctacataact gagttggtca aaaggtacta aatgaatcgt gtttttgaat
     3421 tccttgtcag taaaccgttg cttttgataa tgaaaggaaa gcgtgtctcc ttctattttg
     3481 gtttcttccc ccttggtcaa atgaataggc gactgcaatg gaaattccgc acctctcgca
     3541 aaccaatcac ataaactcgc ccaattttcc ggacctttgt ctccagaata gccccattcg
     3601 acatccatat tctttttcaa ctatacttcc ccctgcatct catatcattt ttatttttct
     3661 tctttcttta caatcgttga gacggtttct aaaaacgcct cttttccata aaattcctgg
     3721 ttcaatagtt ccggaaatat ctctttaaag aaatactgaa cagaaggccg atgttcaaag
     3781 cttttaatcg tagtcactgc ctcaatgaac atctccttat aaactttttc cgggttattt
     3841 ttgatgattt catcaaaaga ttcataaaga aggtcaacct tatctgaaat ggctaatagt
     3901 tctccttcta cggtttcatc ttttccttcg aacaaccgac ggcgataaac ttcttggaac
     3961 tcagctggaa tctcttggtt gatgaattcg tccgtcatct tttcttcaac tgtttgcagc
     4021 atccctctta actctttgct tgcgtatttc accggcgttt tgatatcacc aataaaacgc
     4081 tctgtgtagt catgattcaa tgatttttca tagagcagtt tccaatcgat cggttgtcca
     4141 ttcgcttctt caatgtctcc tagaacttgc gcaatagatg ctacacgata cgaatgtgct
     4201 gcaactgtat gctctgtata tttaaaaaat ccaggtgccc ttgtgatcgt ctctaaattg
     4261 ttcaatccta aaataaattc attcaacccc ataaaagtta cctccctttg agatttcttt
     4321 ttccgaatat catatcatta aataactgat attcgcaaca tttccgctct ttaccatttt
     4381 tgaaacagct cccttaccaa aaaatagaga aaatctatat ataatagaaa aaagagaaga
     4441 gattattctc ttctttctgc taaccagtct tagaaaaatg aattttaaaa aaatcaaaaa
     4501 ctgatcacga tagaagtttc ttttcatacc tgatgaaaag atgcttctcg caatcagttt
     4561 ttggattttt gctattccaa ttgatgattc tggagacaca aatcggattt ctctatcttc
     4621 atcaagcgcg cttaaatctg ccaattttca ggatcttttt tccattcttt tagcagagtt
     4681 aattcttgct catcgatata acgatcttct aaagctgctt caatcaatac agaataattg
     4741 gtcaacgtca taagagggat ttcggctttt tcgaaatttg cttttccttt tggcaactca
     4801 tacgtaaaga tagccgcaac accaaggata tccgcacctt ctctttttgc tgcttcagct
     4861 gcttccaaga cacttccgcc tgtagaaatc aaatcctcga tcacaaccat cttctgacct
     4921 tcaaatatac gtccttcgat ttggttacct ttcccatgat ctttcgcctt acttcgaata
     4981 tagaccattg gcaaatccag tatttccgct acccatgcgg catgagggat tcctgctgtt
     5041 gcagttccag caatcacttg tacttcaggg taagcttctt tgattttgct tgctaatcct
     5101 tttgcgatct cttttcggac ttttggatag ctcatcgtga ttcggttatc acagtaaatt
     5161 gggcttttga ttccacttgc ccatgtaaaa ggattacttg gatttaaaaa tactgcttca
     5221 atttctaata agtcttttgc gatactttgt tcaacattca ttttaggtta gctccattct
     5281 gtttgaatcg tttgatatgc tttataagga ttagttgact gagtgattgg tcgacctata
     5341 acgataaaag ttgagccgat cttttttgcc tgagaaggtg tgactactct tgtctgatct
     5401 cctgcgactg ttccttctgg tcttataccc ggagttaagc aaacaaattc gtctcctgcc
     5461 atttctttga tcgcttctac ttcccaagca gaagaaacca caccatctaa tcctgctttt
     5521 ttggcacagc tagcataatg gatcacactt ttttctaaag aaacttcgat tagttgatcg
     5581 gcatgcattt cttcttcact tgtagaagta agctgagtga tagctagaag tagcggacgt
     5641 tttccacctt ctggagtccc ctcttctaat cctcgcattg ccgcctccat catacgaata
     5701 ccgccagcgg catgaacaca ggtgagatca acaccaagct ttgccaatcc ccgcattgct
     5761 ttttcgaccg tattcggaat atcgtgaagt ttcagatcta aaaatacatt atgaccagcc
     5821 tcttttagat aacgtacgat ttcaggtcct tcttggtaga acaattccat tccgattttc
     5881 acaaacaatt tttcttcttt cgggaaaaat cgaagaaagt cttctacctc ttgcctagtt
     5941 gaaaaatcta atgcaataat tggtcgttgg tctagttgat tcatcgttca cgttcctctc
     6001 tcacttcttt gattaatctt tccagcgatt cgatgcctag ttcgctcatt cgcacaggga
     6061 gctctttaat tagtttagga cagatatacg gatcggtgaa attcgcggtc cctatagcta
     6121 cagcacttgc tccagccata aacatctcaa gaacatcatc cactgtctgc acgccgccca
     6181 tcccaatgat tggaaggctg gatatacttg ctacttggtg aatcaaacga atagcgacag
     6241 gcttgattgc tggtccggag agtccacctg tttgattggc taaaatcggt tttcttgtct
     6301 taaggtcaat ccgcatacca agaagagtat tgatcatcgt aaacccatct gcccctccag
     6361 cttcgattgc ctgagcgatt ggaacgatgt ctgttacatt tggggacaat ttgacataga
     6421 caggaacaga agaaactttc tttactgctt gtgttaattg aaaagcaaca tcagaatctg
     6481 ttccaaaagc aattccgcca tgtttgacat ttgggcaaga aatgttcagc tcgattgctt
     6541 tcacatttgg tgcttcgcca attttgctac aaacttctac atagtcttct tcacaagcac
     6601 cagcaacatt tgcgatgatg ggtaactcat tgtactcctc taattctgga agaagtttat
     6661 gcataacaac gtctagacca ggattttgca aaccaattgc attcaacatg ccagatggtg
     6721 tttccgccac tcttggcgtg ggattgccaa agcgggcatt tggagtcgtt gccttgacca
     6781 tgatcgatcc aagctgattc aaatcatagt attttccgta ttctttgcca aaaccgaaac
     6841 agccgcttgc cggcatgata ggatttttta attctaggcc aggaagtttg accgctaaag
     6901 gattctcatt catataatta cctctcctat tttaaaaatc ggtccttcgt cacaaacttt
     6961 cacacttttt gttcctgttt catcttccgg cgtatgacaa acgcaagcat agcaagcccc
     7021 tatcccacat gccatgcggg attctaatga taactggaca ttttgatgcg aagaaaacag
     7081 ctgttccact gtcttcaata acccgtttga accacatgca aaaacagctg taggttccgt
     7141 cttcgttcct aacaataaat taccgacatt tccgtgcata ccgtatgttc catcgtcagt
     7201 agcgattctt gtttctccta gacgattaaa ttctttttca taataaacga cttcatgtgt
     7261 ggcaaaacct aaaaaatgcg ttggcttaat tcctttttcg actaactgtt ttgataactc
     7321 atatagagga gggacaccga ttcctccacc gattataaat acttcgtctc ctgtatgaag
     7381 attggacaaa tcaaaaccat tgcctaaagg acccatgaca tctaaatggt ctccggcaga
     7441 aagagtagag aagactctag tcccctcacc ttccacccga taaatgatac ggcaagtatt
     7501 tgtttcgtgg tcgatatgat tcaagctaat cggtcggcgt aatagcaagt ctgcacgcgg
     7561 cacgagaata tgcaagaact gtcctggttg ctgcatttct tttactagat cacctttcaa
     7621 tgtcatttca aaaatctttg gtgccagctg tttttgctga acgatttcca tcatttcttg
     7681 tttcatctgt cccctcctgc aacggttttt cgtctttttg tcttaacatg tgctcgccgt
     7741 taaatagggt tagttgaaaa agcacgggat tccatcactc gaacgatcgc atctgctgtg
     7801 tctaaagaag taaacaatgg aataccatgt tcaactgctt ctcttcggat gatgaaaccg
     7861 tctttagaag catttccccg atctttatca atcgtattga caaccacttg tgttttacca
     7921 tctcttatta agtcgactac atttttttct gctgcttcct cagaaatttt cgctactgtt
     7981 tcaacgacca gaccattttt ttcgaaataa gcagctgtat gtttcgttcc tatcagacta
     8041 tagccaattt ctgtaaaacg tttagctaat tctagtgctt cttcttttgt ttcgtccgca
     8101 atcgtaaata atacggctcc atattcaggc aagtgtaatc cagaagcttc gaatgccttg
     8161 tacaaagctt tgtctaattg tctgtcagat cccattactt ctccagtcga tttcatttca
     8221 ggccctaagt aagtatcaac tttctgcaat ttcgtaaaag aaaagacagg tgctttaaca
     8281 tgaacttctt ttgtttctgg ataaagtccg ttttcataac caagtgtctt tagtttctct
     8341 cccaaaatag ctttcgtcgc aatttgtgcc attggaattc ctgtcacctt acttaagaat
     8401 ggaacagtcc gacttgctcg aggattgact tcgatcacat aaacctcatt ttcatggatg
     8461 acaaactgga tattcatcat cccgacacaa ttcaaaccta atgctaagcg gatcgtgtaa
     8521 tcttcgatcg ttttcttgat cgattcagat aatgtttgag gtggatacac agccattgaa
     8581 tcccctgaat ggacaccagc acgctcaata tgctccatga tccctgggat gagtactgtt
     8641 tcaccgtcac aaatcgcatc cacttcgcat tcaccaccaa gcaagtaacg gtccactagt
     8701 actggatgtt ctggagatgc tttcacagca tgttccatgt aatcttctaa atctcgctgg
     8761 ttttcaacga tttccatcgc acgtccgcct aatacatagc ttggacgaac aagaactgga
     8821 taaccaattc tcgaagcgat aaccacggct tcttctttac ttgtagcagt atcccctaaa
     8881 ggttgaggaa tatccaactc tttcagcgct tgctcgaata aatcacgatt ttccgcacga
     8941 tccaagtctt cgatcgttgt ccctaagatt tttacaccag cagcagtcaa aggttcggct
     9001 aagttgattg ctgtctgacc accaaattga acgattactc ctatcggctg ttctagctcg
     9061 atcacattca tcacatcttc gaaggtcaat ggctcaaaat ataatttatc cgaaatagaa
     9121 aagtcagtcg aaactgtttc aggattgctg ttcatgatga ttgcttcgta tcctgcctgc
     9181 tggattgctt tgacagaatg cacagtcgca tagtcaaatt caaccccttg tccgatacgg
     9241 ataggaccag atcccagtac tagaattgag ggcttttctg atcgtgaact ttcattttca
     9301 tattcatagg aactataaaa ataaggtgtt tttgattcga attccgctgc acaagtgtca
     9361 accatcttat atacaggaat caaatcattt tcttttctca tctggcgaac ggcttcttcg
     9421 tttatttccc acagctccgc cacttttttg tctgtaaaac cgttttgttt cgctgttttc
     9481 aatatcttgt catccaacgg ctgctgtttc aactgctgtt cgatttctac gatatgcaac
     9541 agtttatcta aaaagaataa atcgattttt gtcaaatccg ctaattcttc tatggtgtac
     9601 cctcttctaa tagcttcagc tacataaaac aggcgatcat cttgtgctcg aaccactttt
     9661 tggattaggt catcgtccgt gatgtctgcc aactcaggaa gttcgatatg gtgtgtaccg
     9721 atttctaaag aacgcacagc tttcaataaa gactcttcga tattccgacc gatagccatc
     9781 acttcaccag ttgctttcat ctgcgtgcct aaaagccgtt ctccgttttc aaacttatca
     9841 aacggccagc gaggaatttt agctacaaca taatctaatg caggttcaaa ttctgcaaaa
     9901 gtcgttcctg taacaggatt tttcatttcg tctaatgtta atccaagcgc tattttagca
     9961 gctagcttag cgatcggata gccagtcgcc ttacttgcta acgcagatga acgagaaaca
    10021 cgcggattga cttcaatcac ataataatta aaactatgtg gatcaagagc gagttggaca
    10081 ttacagcctc cctcgatctt aagtgctcga ataatcgaaa gagaagcatc acgaagcatt
    10141 tgatattcat ggtcagacaa tgtttgacta ggggcaaata cgatagaatc acctgtatgg
    10201 atacccaccg ggtcaaaatt ttccatattg cagacaacga ttgcattatc agccgaatct
    10261 ctcatcactt catattcaat ttctttaaaa cctgcaatac ttcgttcaat caaacattgg
    10321 gtagcggggg aaagacttaa tccattttct gatacgatac gtaattcttc ttcattttca
    10381 cacatacctc caccagttcc gcctaaagta aaggctggac gaacgatgac aggatagccg
    10441 attttatttg caaaatctac agcttcttct actgtattga cgatttcaga ctcggggatt
    10501 ggctgattca attctttcat caactgtttg aatagatcac gatcttctgc ttgatcgatc
    10561 gcagaaagct ttgttcctag aagttctatg ttcaattctt ctaaaatacc tgatgctgcc
    10621 agctccattg ccatattgag gcctgtctgt ccgcctaaag ttggaaggag agcatctgga
    10681 cgctcttttc gaagaatcct tgatacaaat tcaagtgtga tcggttcgat atatacttga
    10741 tctgccactt ctttatccgt catgatcgtc gcaggattag aatttactaa aaccacttca
    10801 tatccttctt cttttaaggc aaggcaggct tgtgttcctg cgtagtcaaa ttctgcggct
    10861 tgaccaatga tgatcggacc agatccaatc accataattt tcttgatatc tgtacgtttc
    10921 ggcatctgtt tactgctcct ttcctgcgtc catcatttcc ataaattcat caaataaatg
    10981 tagtgcatca tgcggaccag gggcagcatc tggatgaaac tgcacactga aagcgggata
    11041 atctctgtgt ttgactcctt ctactgttcc gtcatttact tctacatgag ttacgatgag
    11101 tttttctgga tcaatcgtgg cttcatcgac tgcatagcca tgattttgag aagtaaaatc
    11161 aattcttccg gtcgctactt ctcgtaccgg gtgatttaat cctcgatgtc cgaatttcat
    11221 tttataggta tctgcaccgt tggctaaagc aaataactgg tgaccgagac aaataccaaa
    11281 aatcggtact tttccttgga tttttttgat catttcgatt gcttctggca catcttttgg
    11341 atcaccaggt ccattcgtca gcatgactcc gtctggtgat agcgctaaaa tcgtctcggc
    11401 atctgtgtta tagggaagta ctgtgaggtt acagtttctt ttactcaatt ctcgtaaaat
    11461 actatgtttc aagccgaagt caatgacaat gactttccga cctgttcctg gacttggata
    11521 aggtttgtta gttgagactt gctgcacttg attggttgct agaacggttg ctttcagctg
    11581 atcaaatgca tgttcgaagg aatctccagc atcaactata ctagctttca tcgttccgac
    11641 ttcacggatt ttgcgagtaa gggcgcgcgt atcgatacct gatattccag gaattccttt
    11701 ttgtttcaaa aatgaatcta gcgtcatttg gtttcgccag tttgaagcta cacgtgcatg
    11761 ttcttttact actactcctt tgcatgttgg agaaatcgat tcataatcat ctctatttac
    11821 cccataatta cccaccatag gataggtaaa tgtaatgatt tgaccgttaa aactttgatc
    11881 agtgatagtt tcttgataac cagtcatact tgttgtaaaa acgatttctc cgaagacact
    11941 agcatctgca ccaaaagcct ttccttcgaa aactgttcca tcttctaata taagcaaacg
    12001 ttccatactt ttattctccc ttctgccaca caagttttcc gttgacaaaa gtcatttgtg
    12061 tttcgccttt tactttccag ccgataaaag gtgtattctc cccttttgat aaaaagtctt
    12121 ctttatcgat cgtgcaagtt tgtgtaatat caaaaactgc tacatcagcg ggggcaccaa
    12181 ccgttagcgt tcctgcattc aaaccaaaaa tctcagccgg tttaactgcc aaccaattga
    12241 tcacttgttc caacgtgaat cgaccagttt ctacaaaatg agtatagatc agttgaaacg
    12301 ctgtttcgct tcctacgata ccaaatggtg atttcatgaa actttggctt ttttcttcta
    12361 atccatgggg ggcatggtct gtagcgatgc aatcgatcgt accgtcaagc aagccttcga
    12421 tcaaagcttc tctgtcctcc cgtcctctta gcggcgggtt cattttccaa aagccgaaat
    12481 cttcgggaat atcttcgtcg atcaaaataa gatgatgggg tgaaacttct gctgttacgt
    12541 ggattcctgc tttttttgcg tctctgatta cacggacact ttctttagta gaaacatggc
    12601 aaacatggta atgaacacca gttgcttcag ctagcaacag atctctagca atttgagaag
    12661 actcggttac gcttaagatc ccgggaagac caagttcttc tgccttcttg ccagcgtgca
    12721 taacgccgcc aaataataaa gattcatctt ctgtatgggc tactagggct ttattgtttt
    12781 ttgcagcttc tttcatagcc agatacatcg tcccagctgt ttggacacct acaccgtcat
    12841 ttgtgaaagc aaaagcacct tcttcaatca gtgcttcttg atcaactaat ttctcacttc
    12901 gcagattttc tgtgattggc gcatactgca ataccttcac aactgcatct tttctaatga
    12961 tgtcatatac ttgtctcagc ttttctgccg tatcaggtac aggatttaaa ttcggcatcg
    13021 cgcatacagt agtgaaaccg ccacgagcag ctgagcgagt cccagcttcg atcgtctcct
    13081 tgtatgtaaa tcctggctct ctcaaatgaa catggacgtc cactaaacca ggtgtgatca
    13141 attgtccctt tgcatcaaac acttcatcaa attcggcttc tgagaatcct gtaccgattg
    13201 ctttgattcg cccatcttct atccaaattt ctgctggtgt cgtcatattt tttcgtgtat
    13261 tgatctgacc gtttttaatg agtgttttca ttttttcatc ctcctataat tacgcttttc
    13321 catttagcac tgcttctaag attgccattc tgacgaatac tccattgctc atttgctgaa
    13381 cgatccgcga ctgtaatcct tccactaatg aatcagctaa ttctacatca cggttaactg
    13441 gtgctgggtg cataatgatt gcatgttttt gcaacttctt cgcacgctca actgttaacc
    13501 catgttcctg atggtagcct tcttttgaga aactttcttt tccatcatgg cgttcgtgtt
    13561 gcacccgaag catcatcatg acatcaactt gatctagtag ttcatccaat ggcatataat
    13621 gtccgtacac ttcgaattca tcgtcgtacc attctctagg acctgagaag aatacttgtg
    13681 cgcctagacg ttttaacatc tgcatattgg atttagctac gcgagagtga gtgatatcac
    13741 ctacgatggc aactttcaga ccttcaaaat gaccaaattc ttcataaatg gtcatcaaat
    13801 caagcaagca ttgggttgga tgctgtccgc ttccgtctcc tccattgata atcgaacact
    13861 ggattgtttt actttgtatc agttcgtcat aatagttctc atcaccatga cggataaccg
    13921 ctacgtctac gcctaatgct gacatcgtca gtactgtatc gtatagtgtt tccccttttt
    13981 ggacagagct tgtgcttgct tcaaattcaa tcacttctag ccctagtttt ttctccgcta
    14041 catcgaagct tttatgtgtg cgagtactat tttcgaaaaa gaggtttgta gcaaagtact
    14101 ggcgcttttg cggagtccaa ttagcacctt gcttgaattc ctgccctctg cggatcaagc
    14161 ccataacttc ttgatcagta agtgcctcaa cggtcaataa atgctttaag ctgatacgtt
    14221 ctgatttgat gatcataatg tttcctcctt agttttcttc gcttcgtgaa gtttctggta
    14281 agataagatt taaaatgatg ccaagtacag ttgctaatgc cattgccgac aatgtaaatg
    14341 tgcctacttc aaagacgagt ccgccaattc ctactactaa gataactgaa gcaatcaaca
    14401 gatttttctt tttatcaaaa tcgattttgt tctcgattaa aatcttcatt ccacttgcgg
    14461 caattactcc aaataagata aaactgattc ctgagatgac tggtccaggg atacttaaaa
    14521 tcaaagcgct taattttcct acgaatccta aaatgactgc aaatactgca gctccaccga
    14581 tcacaaacac gctatggaca cgtgtgatag ccagaacacc aatgttttca ccgtaacttg
    14641 ttacaggagg acctccgaca aaggctgcca cgatttgtgc taatccatca cctgtcaacg
    14701 tcttatgaag acccggttct tcaaagaaat tacgtttagt tagtttattc aataccataa
    14761 gatggccgat atgctctgtc atcgtcacaa aagcgatggg tgccattgtt gtgattgctc
    14821 caagatatag ctttggttca tattgtacaa agggaatctc aaagttagga acagcaaacc
    14881 aggcagcgtc tacgattggc ttagtatcca cgattccaaa cagcaaggct acgatgtatc
    14941 cgctaataat acctagtaaa atcggaatca atccgagaaa acctcttagc cacatgttga
    15001 agaaaattgt taatcctaat gtgatcagcg ctacagcaat atacttgaaa tcatacgtgc
    15061 cctgattata catagcattt gttgctgcat ttgccgcaag tcccaacccg ataaccatga
    15121 tgactggacc gacgacgatt ggaggcaaga ttttatccag ccatgctgaa ccgatctttt
    15181 tgatgatcag cgcaacaatc aaatagacta atccagttgt gactgctcct tgtgcaatcg
    15241 ctggataacc atctgttttc atcaaaagct gcatcgctgc aatgaaagcg aagctgcttc
    15301 ctaagtacgc aggtatcttt cctttagtag taaataagta caccaatgta cctagtcctg
    15361 aactgactag cgcaatacct ggatcgatac ctactaagat ggggactaac acggttgctc
    15421 cgaacatcgt gaacaagtgt tgtaaactta atcctaccca atgtcctggg gttgggcgat
    15481 cgtggatatc taacaccacg tcatcattat gaaatccttt tttctccgac atgtttctct
    15541 ctcctctaat cttcctcttt caaaatcatg atgcgatctt gtccatcaag ctcttgcatc
    15601 tctactaaaa tctcttccgc ccgagatgtt ggaatgttct tcccaacata atctgcacgg
    15661 attggcaatt ctcgatgccc acgatcgacc aggactgcta atgaaatttt tcttggtctg
    15721 ccaaaatcca ttactgcgtc cattgctgct cgaatcgttc gtcctgtata caaaacatca
    15781 tcaatcaaaa taacttcttt tccttctaag gaaactggga tgtcagaaga atgaagttcc
    15841 ggttcttctg gattttcttt tttgtcatct cggtataaag tgatatccag ttctcctaca
    15901 ggaatatcga tatcttctag ctgcttcagg cgttcggcaa ttcttgatgc aatgtagatt
    15961 cctcgtgttt tgatacctac caatacgata tcttggatac tatggtttct ctcgataatc
    16021 tcataagtaa ttcgagtcaa tgctcgcttc atggttacct gatctactac ttcttttgct
    16081 tgcattttca ttccccctac ttttttgcat aaaaaaactc ctgccctaag aggacaggag
    16141 gaatgtttag actgagcgta tactgataca ctgatagcta tactatgtca atgagcaatc
    16201 tacttatggc gcaccatacg tatccttgct cccacccttc ttagcctcac gggactaaac
    16261 ttaaaggaat tctattaagt tttatgcttt cgttgttaat tactataccg ttatctaaat
    16321 taaaatgcaa tgttttttct taatttttct aaagtttttt caaaaacttc tggaagaggt
    16381 gcttcaaaga tcatcttttc gtttgtagtc gggtgcgtaa aacctaacat ttgcgcatgg
    16441 agaaactgac cattgccttt caaagttttc ttcggtccgt atactggatc tccagctaac
    16501 ggataaccga tatacttcat atgcacacgg atctggtgtg ttcttccggt ttctagtttt
    16561 aattcaacca gagtaaatcc ttcgaaacgt tccaatacag taaaatgtgt gacagccgac
    16621 ttcccatctt ctcttatcgc ctgcattttc cggttttcct tcgaacggcc gattggcgca
    16681 ttgatggttc ctttttcgtg aggaatctct ccatggacta aagcaacata tttgcgcaaa
    16741 gaggtcttat cttttaattg ctgagctaat gattcgtgtg cctggtcatt tttggcaacc
    16801 attagcagtc cggaagtatc tttgtcgatt cggtgaacaa tacctggacg aataacgccg
    16861 ttgatcgtag aaagatcctt gatatggtac atcagcgcat tgaccattgt gccatgcgta
    16921 tgacctgctg aaggatgaac gaccattcct tgaggtttgt ttatcaccgc tacatcttca
    16981 tcttcgtaaa cgatcgtcaa cgggatattt tctgggacca catctaatgt ttctggttcg
    17041 gggatcaaga cagtaatctc gtctccttgt tttactttgt aatttgcttt gactggctgt
    17101 ccattgacag aaaccgctcc atttttcagc cacagctgaa tttgcgaacg actgtaatcg
    17161 gtgaataaat tagtcaatac tttatcgatc ctaccagatt catggtgaat cgtcgtttta
    17221 agttctgtca tttttttctt tgatcctttt catctaaaat aatataaatt aacatacaaa
    17281 tcactccaca tacaagtgtc acatctgcta cgttaaaaat cggaaagctc ataaaatctg
    17341 tctggaacat atctactaca tagccaagac gaatacggtc gataaaattg ccaatcgcac
    17401 cagctagaat caaactcaat ccaatcatga accagcgatt acctttttca cgatttttaa
    17461 tcatcaatgt gagaatcaca acgactgcaa tgagtgtcac tatagtaaag aaccacatct
    17521 tcccttctag catactccat gcggctccag tgtttcgaat atgattcagt gacaaaatac
    17581 ctggtataag atttttcgtc tctccaagcg ctagattatc agtgatccac catttgacca
    17641 actgatccac tcctactagc aaagcgctga atatccaata aataattaac aaaaaatcaa
    17701 tccttttcta tttgtttata aatatcacga ggtcgtacga tcccgagcag attaccatcg
    17761 ggattcccat ctttagtgat aagtacggct tccaaagtcc cttgctcacg aaacatcgct
    17821 tcaacctcgt aaatatgtgt tttagctgga acaaaatgat aatttgtgta ctttccgttt
    17881 tggatgatca aatccaacgc tcgtttattt gttaaatcaa ccggaccttt ttggctttct
    17941 tttgctagcc aaaacccgat attacgtaaa gtaatcaatg ctacaaattt tcctttattg
    18001 tataacggaa attgtgaata ccttttttct gctactatct ttaacagttc aagtaacgga
    18061 agatcttgtt caaaacctgt tacacgtttt gcaaatcgag gcagcacggt ttcaggctga
    18121 atcagttctt gttcgatcag ctggattcgc ttgactgtcc aatcatttgg ctctgcaatg
    18181 acaaaatcga ctgcgatccg atcatggacg atcgcattcc ttaactgagc aagctgtaaa
    18241 agatcatctt cgtattttct gatcattaat tgttttcttt gagctaggcg tctgacaagt
    18301 tcggtaaatc ccatatttcg tgcatttccc atctcgtctc tcatccattt ttcgattcga
    18361 ttgaaactga ttaaaaaaag atcagagttt gccataattt tcctccttga tcaaatatgc
    18421 ccggtttttt atatagaaaa agaacgcaat caacacaata actgcaaaaa aactgaaaaa
    18481 taaattttgt aggaaaacgg cccccaaccc agttgctaga aataaaaacg gatagatttg
    18541 aagaatcaag taattcattg tgatcacata agcaggcttt gcttctttca ctgtataaac
    18601 ggggcttttt agccaataaa aggtgacctg catcgtaaag ggcacttcca gatcaagcgt
    18661 tatcttttgt tcatgactga gaacactgcg tttttcattg ttgattctta gctgaatcga
    18721 gctacccata ccgtaaaaac cggtttttct tataaatgtc gttttcatca taccctccta
    18781 ttatgcttta gtatagctca aaatacaata aagaaaaaga atgatcctag tgtaaacaaa
    18841 attaattccc tatcgtctaa aaaaagaagc tgtagtcaaa atacagctcc ttcgatggta
    18901 gattataatc aagcttaaaa caatcccaac acttctccgt catttgtcac gtccatattc
    18961 aatgcagcag gttttttagg caaaccaggc atcgtcataa catctccagt caaggctact
    19021 aaaaatcctg cccctaattt tgggatgatt tcgcggatcg tgatggtgaa atcttccggt
    19081 gcacctagca gtgaaggatc atcagaaaat gaatactgtg tttttgccat acaaatcggc
    19141 agtttgtccc atccattctt cgtaaactct tctatttgtt tttgcgcttt tttgctgaaa
    19201 acaacaccat ttcctccgta aattttcttg acgattgttt ctgtcttttc ttgtatcgtt
    19261 tcttctaggc ggtataatgg cttgtaatta gcttcttttc tatcaatcaa tcgtactaca
    19321 gcttttgcta aatcaacgcc gccttctgct ccatctgccc atacactcgc tctcttggca
    19381 agaatcccct gattttcaca caagtgctcc aacagtgtga gttcattgtc tgtatctgtt
    19441 acgaattcat tgattgcgac gatcacaggt agctgatatt gttccatatt acgtatatgg
    19501 cgctttaaat ttgcaaaacc tactttcaaa gcatcaagat tctcattttt aagttcatct
    19561 tttttcattc cgccatgcat tttcaatgca cggacagtgg cgacaatcac cacagcatcc
    19621 ggcgcttttt tcaagttagg tactttgata tctaaaaatt tctctccgcc aagatctgca
    19681 ccaaatcctg cctctgtgac aacgtaatct gctaatctca atgctgtctt ggtagctaaa
    19741 atactattgc agccatgagc gatattggca aacggtcccc cgtggacaaa agctggtgtt
    19801 ccgtaaattg tttgtacaag attcggcttg attgcatctt tcagcagtaa tgccagagcg
    19861 ccttctgctt tcaagtctcc agcagtcaca ggctgacggt caaatgtata gccgacaacg
    19921 atccttgcaa gacgagcctt taaatcttca aggtctgccg caagacacaa gatagccatg
    19981 atttcgctgg caactgtgat atcaaaccca tcttctcttg gaacaccttg gattggccca
    20041 cccaagccaa caattacttt acgcagttca cgatcattga gatcgactac ccgtttccaa
    20101 atcactcggc gggcatcgat gttcaattca tttccttgat gaatatgatt atctaaaaga
    20161 gcagataatg cattattagc tgttgtgata gcatgcatgt caccagtaaa atgcaagttg
    20221 atatcttcca taggcaatac ctgtgcatat cctccgcctg cagcaccacc tttgattccc
    20281 atcacaggac caagtgaggg ttctcgcaat gcaataacag attttttatt gattttattg
    20341 agcgcgtctc ctaaccctac agtgatcgtt gactttcctt cgccagctgg tgttggattg
    20401 atggaagtaa ctaagatcaa atgcccctca gcgttatcct ttgatcgatt gattccagaa
    20461 aaattgattt tcgccttata tttcccatac agttccaaat cgtcttcctt aagatctaat
    20521 ttactagcca cttcaacaat cggttctagc tctgtttctt gtgaaatttg cagatcattc
    20581 ttcatttgat tacccctttt cacgaacttt attcaacaaa atatcttctt tgttaagata
    20641 tgccaattat accttttttt attcagaaaa aaaacataaa attacaggtt tttaatttat
    20701 ttgacgtact tataaatact ctttataatg aaggctatga tcagacttta gaaaggtcgt
    20761 gagtgctttg accacaggaa ttgtaaaatg gtttgacaac aaaaaaggat acggctttat
    20821 cagttatgat gacacagaag aaatttttgt acattttact gcgattgaag aagagggatt
    20881 caaaactttg gaagaaaatc aagtggtcga atttgagatc atcgaaggga atcgaggaac
    20941 acaagctgcc catgtcaaga aaggcaacgt tcagactacc gatactagta tgcatgaata
    21001 gataaacaaa tagagtgaga cgctaaacgg gatgaaccgt acgtctcact cttttctttt
    21061 cctgtaaaaa ttcgtttttt taggttctga tttttaaaat tagctttttc tttttttcgt
    21121 ataaggataa ggaattgatt ctgatttggg tccgtttttt tcaaaatgat caaaaaggac
    21181 tacttgatct ttttttcgca tcatgaaaac agatggggct ttctcatctt gcaacatcat
    21241 ttgcacccca gtattagttg gcgtcaaaga tcgaatctgt ccgacagata tttctcggtc
    21301 tttccaaaaa gcagcataac gtataatcac agagtttgat tttaaaataa aagaacgccg
    21361 caaacctaga aatagaaaaa caagaaaaat acctaaaaca aaattgcttt tccaataagg
    21421 acctgtgttt tctaaagaaa gaatcagact aaaaaacaga atgatcaagg tcaatgacca
    21481 atagatgatc gtatgtgcca gttcaggctg ccatcgaata ttttttttca ttctctaacc
    21541 tctcaccgat tcagtaatga tataatctta ccataacatt agtttgaaca aaaaggagaa
    21601 tctcttttta tgttaaaagt atacattgat gcctctacaa aaggcaaccc tggtcctagt
    21661 ggaggtggaa tcttgattgt ctatcaaggt aaacaagaac agctatctat cccgctttct
    21721 atagggacaa accatcaagc agagttcgaa gtctttttaa aaactttaga atttctaaag
    21781 aaaaacgact tacagaatga aacgattttc tgtttttcag acagcaaaac actagtttct
    21841 acggtcgaca aaaacgcaac gaagaacgag ctcttccttc cctaccttca aagaatccaa
    21901 gaacttctat ccgaattttc tttattgatc ctgcaatggt tgcccgaaaa caaaaataaa
    21961 ggagcagata atcttgcacg tcaggctctc cataaacaat taaaagaaaa aaagactctt
    22021 taaattaaaa actttaagga gtctttttat agtttctcat ttaatataaa agataattgt
    22081 gatcaaacgt aatttccaat tggtaatctc cgattttttc ttctatttga ctacgtaaga
    22141 ttctttctag ttctgtatca acaaactgga atttctcagg gaccactaca tcaaattgca
    22201 gcgtttttcc ttgatgaatt actctaaaat catgaatatt aagccctgta cctgtttcaa
    22261 gaagaatttg ctttaactgc cgcaagatat tatagtattt ttcgttatca acaggcattg
    22321 gatccaagtg acagacaagt tccacatcca aagacttttt aaagtctttt tctatcagat
    22381 caataatctt atgagccaca ttcaaattca ttgattcatc tacttcgatg tggactgatg
    22441 caaagcgttt attgggtcca tagttatgca ccaataaatc atgatagcca agtatatcat
    22501 cgcaagcatt taaatgctct tccatttctt caatctctgc tggcgttggg cgacttccta
    22561 atagttcgta tacaaaattt cgaagcatcg tcaatccact ataaaggata tataatgcta
    22621 aagcaaaacc tatatatcca tcaatacgcc atccagttac ccattcgatt gctgctgaaa
    22681 gcaatacagc cagtgtagta aagacatcat tataactatc tgttgctgta gctctcaatg
    22741 tttcagaatc aatggattgc gcaataacct gatacatttt gccttgtgca aatttcaaaa
    22801 agatggaaat gattaggaca aaaaagacga tgggtgttaa agagacattt tctggatgga
    22861 tgattttttc agcagaagac tctaaaaatt gaaatcctac ataagtaatg atgatcgaaa
    22921 caaataaccc actgatatat tcgaagcgtt cgtgtccata aggatgttcc tgatctgctg
    22981 gctttgcagc aattttaaat ccgatcaaag tcaatatgga tgaagcagta tctgatagac
    23041 tgttcactgc atcagccata atggagacac ttcctgaaaa aagcccgatc attagcttag
    23101 agacaaacaa gatcagattc gtaaccaatc ctaagatacc cgctagtact cctttttttg
    23161 tccgctgttg cggtatttgt ttcttttttt cttcttgttt cttagccaag ttttttaccc
    23221 cttctagttt gcttgttgct caggtaaaaa gatggagagg acgattgttt tcctctcctc
    23281 tcttcctttt tctatctatc gtgcgtccta ttactattaa aagatggtca ttattctggt
    23341 ttcaacggtg ttgctgcaaa taacgctttt gctagtaatg gtgttatgat tcccgcacct
    23401 attgcttctg gtatcccatt gattgctgca acccctgcta aggttttaaa taaaagagca
    23461 gagtctacac cataggcatc tgccgttgca cctgtataaa ataatcccat gaatcctaac
    23521 actaagactg tattgaccaa tgaacccagt acccctgcaa aggctgagct gatcgttatt
    23581 gatttatttt tttgataaat ccagtggaaa accaagcctg ctactaagcc aacaagtact
    23641 ctgggaacta ccgagataat cggattcgtg aacactaatg tatcaaatgg cgttgttggc
    23701 atggcatagg cacgaacaat tgtagcgatt ccccaaaaca agccaatcac catgccatct
    23761 tttgggccta atactactgc agcaataatt actgtgatat ggataattgt taaactaatg
    23821 aatcctaatg gaataaaccc cagccaagga accatcgctt gtacgatgat gattgctaac
    23881 aagatcgcac gtaagactag tcgaaaggtc ttatttctac tattcatttt ttcacccctt
    23941 tttatttata ctaatcgtaa aaatttctgt cactttcgtc aactaaagac catccgaatc
    24001 cgaccatttg attagatgcg ccatccaatt gaaaaaagta tgagggcaag acttgtttgt
    24061 cttcgccccc ataatcatgt ttcgttcaat gtttgaactt ttgtttttct gtcaaacgta
    24121 aacgccctat tgttgcgcaa cccattcttt cgcagcttta agtgcatctg gaataccagc
    24181 aggatttttc ccgccagctt gtgccatgtc tggacgtcca ccaccgccac cgcctacttt
    24241 cggtgcgatt gctttaatca agtcgccagc ttttagtcca gcttcatttg attctttcgt
    24301 cattgccgct agcagactga cttttccttc ttgttcgttt gctaaaacaa gaatatctga
    24361 aatatttttt tgtttccatt ggtcagctaa ttgacgcagc tgattcatat ctttcacttt
    24421 tacttgtgct gcaatgattg tttttccatt gatcgtttct ggatctttga atacatcacc
    24481 agcttgttga ttcgctaact tgctagctaa ttgttcattt tccttttgta gctctcttac
    24541 ttgctgttgc aattgttccg cttttgaaac aacttctttc aattgaggtg atttaacaat
    24601 tgttgctact tgttttagtt gtttttcttc ttcttcaagt agttcgtacg cttctttact
    24661 tgttacagcc tcgattcgtc gcacgcctgc accaattcct gattcagaaa cgattttgaa
    24721 gattccgatg ttttctgtat ttgctacatg tgtgcctccg cacagttcga ttgaccagcc
    24781 gccaatattt actactcgaa cgtcatgtcc gtatttttca ccaaacaaag ccattgcacc
    24841 catgtttttg gctgtatcga tatctgtttc aattgtttca actgggatag cttcccagat
    24901 tttttcgttg acgattcttt ccatttcagc taattcatct gaagtgattt gaccaaagtg
    24961 ggtaaagtcg aatcgtaaat gtccaggagc gactaaagaa ccagcttgat ttgcatgctc
    25021 gccaagtact tctttcaatg ccttgtgcag tagatgggtt gctgtatggt ttttgatgat
    25081 ccgattgcgc atcgattgat cgatcaatag atgataggtt tgtccttcac tcattggtgc
    25141 ttttacttct acggtgtgca taaattgacc attaggcgct ttttgaacat ctgtaacaac
    25201 tgctacgatt tcgcctactt cattcatgat ccatccttga tccgctactt gcccacccat
    25261 ttctgcatag aaaggtgttt gatcaaagat catttgagct tcaccttctg cgacttcatt
    25321 caaaagagac tcacctttaa cgatgaccaa taattgacta tctgattctt gttctgtgta
    25381 tccaatgaat ttactttcta ctttgatatc tgtcaataaa gcagattgta cccccattga
    25441 tttttcagta ctgcgggcag agcgagcacg ttcgcgttgt gcatccattt ctttttcaaa
    25501 accagcatga tcaactttca gtccttcatc ttctgccacc tcttccgtta attctaccgg
    25561 gaagccatat gtgtcgtata gtttgaagat gtcttttcct gctagagtcg tcccgttttc
    25621 gttttttact tcttggatca cttgatttaa gatttccaaa ccttcattga ttgtttcatt
    25681 gaaacgttct tcttctgtac ggataacttt ttcaataaat tctttttgtt gaagtacttc
    25741 aggataataa cttaccatga tttccccaac aacagggact aaacgatata agaatgcttg
    25801 ttcaatacct aattttttcc catgcatgac agcacgacga agcaaacggc gtaagacata
    25861 ccctctccct tcattcgatg gcaatgcacc gtcgccaata gcaaatgaaa gggcgcgaat
    25921 atgatctgcg attactttgt aagaaatatc tgttactggg ttttcaccat attttacttg
    25981 tttgcttagc ttttctacgg cgtggataat aggcataaac aagtctgtct caaagttcgt
    26041 tgacgcatct tgaacgattg agaccatgcg ttccaatccc atccccgtat caatgttttt
    26101 atgaggaagt ggttcaaatg tgttatcagg cttatggttg aattctgaaa atactaagtt
    26161 ccagatttct aaataacgtt cattttctcc tcctggatag ttttcaggat cgtcttctgc
    26221 taaatcgtta taagcttctc cacggtcata gaaaatttcc gtatccggac cacatgggcc
    26281 tgcaccgata tcccagaagt tgtcttctac atcaataatg tgatctagtg gcaggccaac
    26341 ttcttcatgc cagatgcgtt ttgcttctgt atcttttgga taaactgtta cataaagttt
    26401 ttctggatcg aatgccatcc attttggatc agtcaaaaat tcccatgccc agtggatggc
    26461 ttcatttttg aaatagtcac caatcgaaaa attacccagc atctcaaaca tcgtatggtg
    26521 ccgtgctgtt ttaccgacat tttcgatatc atttgttcga atagattttt gggcatttgt
    26581 gattcttgga ttttctggca caactgaacc atcaaaatat tttttcaatg ttgcaacacc
    26641 agagttgatc cacaataagg ttggatcgtt cacggggatc aaagacgcac taggttcaat
    26701 cgtatgtcct ttagattgga agaaatcaag aaacatttgt cgaacttgtg cactacttaa
    26761 ttgtttcatg tcattacctg ctttctataa attaaataca aaaaaacacc atcacagcca
    26821 aggacgaaaa ctcgcggtac caccttgatt gcaatgatgt gtaatcatta cctcttaaac
    26881 tcgataacgc tgagctgcgt cggtatttct accaaaatag aaaaagggag caatttgatt
    26941 agtgactatt cttttttcag ccaagaaaga attttctgtg agtcttaaaa aacaaatcat
    27001 atccttttcg tacttaatta gtatacgcat tctattgatc actgtcaata tctcaatttt
    27061 tattttcatt tccttttggt catactccac gatttttggt acgataagaa taaaggaatc
    27121 aatacatctc tgctattcat gacaaggagg aatatgatga aaaaaatagt tggagcggat
    27181 gaatggatac gcgcagctag ctgctttttg agatatcaag tttttgtatt agaacaaggg
    27241 attcctgcag aactagaatt cgacggaaaa gatatcccgc aacaaaccta ttatctattt
    27301 cttgatcaaa aaagaccagt agctactttg cgttatgaaa agaaaacacc tacttgcttc
    27361 aagccggaac gattttgcgt agcaaaagaa taccgaggaa aagggttagg cggtcagttg
    27421 cttgaagctg ctgaaaaacg ggcggtttca gaaggttgtc agactagtta tgtagtagct
    27481 gaaatgacgg ctgtagattt ttatgaaaaa caagggtatc atacttgcac agaacctttt
    27541 attgaagatg aagtactttg tatcggaatg aaaaaaagtc tagcttaaaa acaagagatt
    27601 gtgacacgcc ttttgtcaca acctcttgtt ttttatttat gtgaattttt cttattttta
    27661 cgagcagtac ggctttgctg tctgcgttcg attttgcgtt cttttttatt tttttctgca
    27721 attgcccaat cgattttttt cttataacca ggcttgatct ttttcttttt cttcttcaca
    27781 agaccaatca gcgtgggatc taatacatct tttgattttt ctcgtttggc acgtctatta
    27841 cgatcgtatg ttttgacgat ttccccgttt ttgatttctt ttggttcaaa tgagacgccc
    27901 aatttttcta tcgcatcaat ggcttgctca tcatttggcg aatataacgt aatggccgtt
    27961 ccttttaagc cattacgtcc agtacgtccg acacgatgga taaagaagtc tagatcttct
    28021 ggaatttctg cattaataac atgagagaca ccttcgatat cgatccctct agcagctaaa
    28081 tcagtcgcta caacatattg atactccaga ttctgtactt gtcgcatcac tcgttttctc
    28141 tctcttgggg tgatgtctcc atgaatcttt gctactttca agccttggtt tttcaagtaa
    28201 tcggcaattt catccacatg ctgttttgta ttggcaaata cgattgctaa ataaggatga
    28261 ccaattgtca gcagttgata aatcatttga ttctcatctt taccttttgt tgaaatcagc
    28321 caattttcaa tgtcttcaga aataactgct tttggtttga tttcttcaat gattggattt
    28381 tccatgtatt ttcgtaagaa tggacgaagt ttttctggaa tagtggcaga aaaaactaaa
    28441 aactgcagct tttctggtaa tcgacttgca atttggtcta cttcatttaa aaaacccata
    28501 tccaatgtca tatccgcttc atcgacaaca aatgcaaatg cggtgtgaat cttcagcgct
    28561 tgttcattca tcatgtctaa tattctacca ggcgtgccta ctacaacctg tggctgttgg
    28621 tgatgcagac gatttaattg acgctgtttg tctgtaccgc cgacaaaatt cgagacacgg
    28681 atctccggtg tagaaaattt agcgatttgt gtagctgctt catagatctg tgcagctagt
    28741 tccctacttg gagctgtaat aacaacttgt acttcctctt tttctgcatt gattttttca
    28801 aacaaaggca acaaaaacgt atgtgttttt cctgtaccag tttgagattg cccaatgata
    28861 ttttttcctt ttgcaattaa aggaatcaaa cgttcctgga cctctgtggg ctgtttgaag
    28921 ccctttgcgg ttaacgcttc attgataaac ggtttgaagc ggaatatatc aaaattattc
    28981 attcgtgcac ctcttctctt taaattatca cgactttggc attataacac agacaaagcg
    29041 tttttgctca gctaatttcg agaatcatca tcctttgttt ggccaatcgt gctaacagta
    29101 tatgtgtgac tagctttttc ataaaacaga atccgttttt ttctcaaaaa tgatagcaag
    29161 atatttaaaa taaaaatacc ttgtagtaac aagacaccga gagaaatgaa tactgcactc
    29221 atctgcaaca ccgtattcgt tgtcgaattc atgatttgct gaagcaactg ccccaaccag
    29281 cttaaaccat aaaaaagaaa gtacagatac ccgtagcgga tcatcaatgc ttttaaagaa
    29341 attcgttcgc ggtcttcttc caccaaacgg atacgcacaa tttttttgcc aagtgtccat
    29401 ccattggtta taaacggtac aatcataaag tataccccta cttctaataa aagccaccag
    29461 atatgagaag taactgcccc tgaatcgaac gcaattttaa agaaaatcgc cgctaccaaa
    29521 ttaataagag ataaaaatgt ccagtcgatc aaataagcga ccaagcgtcg agtcaatgag
    29581 acagtctttc ctttttcata agaaagttca tccattcgtc ttcttgtagg aagcataaat
    29641 gtaaataacg gcgtaacgac aaaaccaatg attccaccca atgtatttgt cactaaatca
    29701 ttcacatcaa ataagcggta tggtcttggg tagataaaat aaagtccact tagctgcgtc
    29761 aattcaaaaa atagagaaag gcagaaacta gcaatcatcg ttttcataaa agaaagccgg
    29821 aaataatatc ttaaataaat gccaaacggt atgagtaata aaacattaaa agctggttcc
    29881 aaaaatacac tctgcttcat tgccggcagg taggtactag gttcagacaa gaccaatacc
    29941 gtgttgtctc tgaaatgttg ccatgaagca aataaatgca gctccatctt tggccctgtc
    30001 atttgggcaa ccgtctcctt tgccggaagt ggtaagatca ccaaaaaata cgcacacaat
    30061 aaataaaaaa cgaaagaata caaaataact gcccttgtta ctagaaatgt tccatacttt
    30121 cgatattcat aaataaaaaa aacagatgag atcgctaagg ctaaaaatgg aaaaacaatc
    30181 agcgcaaaac gaatcggttc gatataactt gccatatgac tcctccttga ttctttgtat
    30241 ctctcttatc ttagcagtcc tttgctgttt caagcaagta acgaggctat tatttctcat
    30301 ttctttcaaa gtaaagtaag ataaacacaa agggggtgtc gagatgctga atatgtactt
    30361 tgtttttggc gtacctattt ttttactgtt cctttatgct acgatcgctt atgtaagaaa
    30421 aagaactaca attcattatt taggatttat tctcctgatt atttcgggtt tcatgctagt
    30481 cttcaatctt cagacttggc agcaagcact tcttgaaatg gataaaatga ctccacatgc
    30541 tttgtctaaa gtgcttggct accctgtcta tctgatttgg cttcccattt tcatttctgg
    30601 ttgcttggtt ttattaaata tttatcgcgg cgtacgccga atagttcagt tacgcaaatc
    30661 aaagtaaaag acagaaatcg gttgagcccg atttctgtct tttactttgc tatttcatcg
    30721 tagacaaaac gacatttacg tgatcaaaat taacgagtac ttttgacatt tcttccacgt
    30781 actcctcatt taaataaaat attttgtttg gcagagaagt gcagttctaa taaaattcga
    30841 atgttttagc tatctacgtt ttaaatagag ataaatcggg ataccagcaa gtgtcaatac
    30901 tatccccatc gaagctaaaa aggtctgagt gataagcgtg cttgatacga taaaagtccc
    30961 tccaatgatt gctactagtg gaataaacgg atacattgga actttgtatg gtcgaaacaa
    31021 atcaggttct tttttacgaa gaagaatgac accaacaaag accatcgtat aaaaaatcca
    31081 aatgacaaag atcagcatat ccgttagtgt atcaaaacca ccgatcatca tcatgccaat
    31141 agcgatgact agctctaaga tacctgcggc tacaggaact ttagttttat catgaagttt
    31201 agcaaagagc ttgctaaaag gcaggttgtt ttcttttgcc ataacataag ggagacgcat
    31261 tccagtaagg gtatagccat tgatggttcc ataaacagaa atcaagatac caactgtgac
    31321 cagtcttcca ccgaagccgc caaaaatcat ttttgcaacg tcacttgccg cattgctgtt
    31381 tcctgcgact ccgtcgatag atgcggttct taagaacacc gcatttacta ataaataaac
    31441 gatcatgatt ccgatgattc ctaaagaaat tgcttttggc aaatctttcg ccggcttttt
    31501 caattctccc gaaatatttc ctacgtgtat ccaaccgtcg tatgcgaaca tcgttgctag
    31561 caagcccgct cccaaggctg agaaaaatga aagattttct cctgcttgga tcggaaacag
    31621 ttggaagtct actccttctt gtcggaacaa accgaaaatg acgatcacaa acaaaggaat
    31681 aagcttgcag acaagcgtaa tcgactgaaa agcccctcca gctttagaac ctaaaaaatt
    31741 gatcaacagg atcgatacag cagctgtaac agctacggga acaatcattg actgggaaag
    31801 accaaataga ttgacgaact gtgtaccgaa aatgatcgac aaggctgcta catttgctgg
    31861 aaaataaatc acgacttgcg cccagcccaa taaaaaagct gctgtatttc cgtaaatccg
    31921 ttcgatatat ttaatcatcc ctcctgtttc tggaatagca gctgccagtt cagctcctgt
    31981 tagtcctgca cagacagaaa tcataccacc gagaaaccaa gaaaacatat gcaaactggc
    32041 ggatcctgta acttctgcta cgcttgcggc tttaaaaaat acccctgcac cgatcactgt
    32101 gcccataaca gtcgataaag cagtaaaaaa tcccatcgta cgttttaatt cattttctat
    32161 ttttacttct tttactggcg tggcttgata ttcttccatc ccttgtcccc tttcatacca
    32221 tagccaatcc caaaagtata aaaaactttt tggatgtggt tcttgtttta taccgtctct
    32281 accaattttt ctttcagttt ttccaacata tcctttgtca tcacatctaa gtcgtatttc
    32341 ggcgaaaagc cccattcctc ttgcgcacaa gaaacatcta gtgaatttgg ccaagattct
    32401 gctattgact gacgtacagg atccacatca taatccattt caaaatctgg tatgattttt
    32461 tgaatagatg ctttgatctc ttccgggtca aaagacatcg ccgatatatt gaaggcattt
    32521 cgatgaacca atcgatcagg atctgcattc atgagtttta taatggcatc gatcgcatct
    32581 ggcatataca tcatatccat tgatgtacct tgatcaatga aactagtgta ctttccttct
    32641 ttgattgctg aataataaat atcgactgcg tagtctgtcg taccgcctcc tggcaaggtt
    32701 gcataagaaa tcaatccagg gaaacggaca ccacgagtat ctacgccata tttcacataa
    32761 taataatcac atagtagttc tccagctacc ttcgttaccc catacatggt tgtaggacgc
    32821 tgaagagtat cttgtggggt atgatctttt ggagtatttg gaccaaacgc gccgattgaa
    32881 cttggcgtaa aaaatttcag ctggaattct ctagcgactt ccaatgcatt gaccagccca
    32941 gtcacgttca aattccaggc taattgtggt tttgcttctg caacagctga caaaagagca
    33001 gccaaatgaa tcaatgtgtc cacttgatat tgttctgcta tgctgcgcat tttttcgtaa
    33061 tccattacat ctaggatctc aaagatatcg tttttctcaa tgacttcagg catgcgtata
    33121 tctgtcgcaa tgacattttc actgcctagt tcttgacgta gccgtgtgat caactctgaa
    33181 ccaatttgtc ctaaacatcc tgtcaccaat acttttttca tgatgatcct ccctgatctt
    33241 ttttactact atcttcagat gattaacaat atatgcgtga acatgttctc taattttaaa
    33301 tagacgaaaa aactaaattt agttaaataa tttccatttc ttttcctatt ttttgataaa
    33361 ctgctactgc ttcatcaagc atttccctcg tatgttccgc agtcggcata tttctgatcc
    33421 tgcctgtccc aagaggcaca gttggataaa cgattggttt agcataaatc ccatgttcga
    33481 tcagcttctt agagaaagtc tgagtcactt tttcgtctcc caaaatgact ggagtaatag
    33541 gtgtttcaga cataccgatg ttatagccta cttttttcaa ttcttcttta aaataattag
    33601 cattttccca aactttttcg acaagttccg gatgttcttg catcaaagta atcgaagcca
    33661 atgcagctgc agctgcacct ggagttagcg aagtagaaaa taggaatggc cgacttctag
    33721 ctttcaacca gtcgattagt gttttcgatc cagctacata acccccaaca acacctatag
    33781 ctttcgataa cgtgcccatt tgcatatcga ttttgtcgct taatccaaaa tgcttgacgg
    33841 ttcctgcacc ttttccagtt acgcctgagc cgtgcgcatc atcgacgtag gtgatcagtc
    33901 catatttttc aacaatcgga ataatttccg gcaatcgtgc aatgtctcca tccatggaga
    33961 aaacaccatc tgtgatatac atgatttttt tatatttctt actttctatc gcttcctttg
    34021 cttttttctc aaggtctttc atatcttgat gtttaattcg gatgattttt gctccggata
    34081 agcggcaacc gtcaataata gatgcatggt ttaattcatc cgataagata gcatcttctt
    34141 ttgtcattac tgcagagata gcgcccatat tgcagttgaa tccagattga aaggcgattg
    34201 ctgcttctgt ccctttgaat tctgcgattt tttcttctaa ttgctgatgg attttcagcg
    34261 aaccattgat cgttcggact gctcctgctc ctacaccata agtttcggtt gcttcaatac
    34321 atgctttttt caattcttcg cgattggcaa atccaagata attgttggat gctagattga
    34381 tcatcttttt tccgtctacg atgatacaag caccattttc actttctagt atgtcgatcg
    34441 tattgtataa ccccttttct ttcagttgat ccaattcttt ctctaaatac attgttagtt
    34501 ctttggaaga cattgtctcc acctccatat tcatctgtct tgcagaacat accaaacata
    34561 tatcgtgtca ttcatctaca aagcaagtat gctatatttt tgataacgct tacactgatt
    34621 atgagaatta tttaaccaca ttttttattt acagtatctt tttactttca aatgacttat
    34681 atagtatgaa caattacctt ttagataatg atctatttta ctctacctgg gcagataaat
    34741 acaacacaac cattgataga agccctttcg ttaaaatcaa ttgtattctg aatatttaat
    34801 ttatttattg catagaccaa taaaaataca taaaatttcc atcttcgttt atcagcaatt
    34861 tttaatttta ctctctgaat atttcttaaa agttttactt gttgaattcg aaaaaaggac
    34921 tgtgacaaaa gtcttgtcac agtcctattc ttccgaataa
//
LOCUS       DACGEU010000020        34662 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.020, whole genome shotgun sequence.
ACCESSION   DACGEU010000020 DACGEU010000000
VERSION     DACGEU010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34662
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.020"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(313..2205)
                     /locus_tag="IXR40_000912"
     CDS             complement(313..2205)
                     /locus_tag="IXR40_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4360781.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            complement(2202..3929)
                     /locus_tag="IXR40_000913"
     CDS             complement(2202..3929)
                     /locus_tag="IXR40_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4360782.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            complement(3945..4595)
                     /locus_tag="IXR40_000914"
     CDS             complement(3945..4595)
                     /locus_tag="IXR40_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAQ4360783.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            4799..5095
                     /locus_tag="IXR40_000915"
     CDS             4799..5095
                     /locus_tag="IXR40_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HAQ4360784.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            5287..5907
                     /locus_tag="IXR40_000916"
     CDS             5287..5907
                     /locus_tag="IXR40_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HAQ4360785.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(5999..7165)
                     /locus_tag="IXR40_000917"
     CDS             complement(5999..7165)
                     /locus_tag="IXR40_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAQ4360786.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(7177..7530)
                     /locus_tag="IXR40_000918"
     CDS             complement(7177..7530)
                     /locus_tag="IXR40_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HAQ4360787.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLKTVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            7658..8680
                     /locus_tag="IXR40_000919"
     CDS             7658..8680
                     /locus_tag="IXR40_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HAQ4360788.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            complement(9119..9553)
                     /locus_tag="IXR40_000920"
     CDS             complement(9119..9553)
                     /locus_tag="IXR40_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360789.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLMKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(9663..11522)
                     /locus_tag="IXR40_000921"
     CDS             complement(9663..11522)
                     /locus_tag="IXR40_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HAQ4360790.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            complement(11640..12800)
                     /locus_tag="IXR40_000922"
     CDS             complement(11640..12800)
                     /locus_tag="IXR40_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-3-phosphoglycerate dehydrogenase"
                     /protein_id="HAQ4360791.1"
                     /translation="MYHVHLIDAIPEQEIEKLQGEYFKIIDDLPAEGIVIRSTKVKDE
                     WLTPDLLAISRAGVGVNTINVEKASENGTIVMNTPGVNANAVKELVLCCLLLSSRPII
                     EASRMVQTLTGPNILEQAENKRSAYVGRELQGKTIGLLGLGAIGTKVALSCYSLGMDV
                     LGYSIRDAQLDYVRQADLETVLSTSDYIVVMLPLTEDTKGLIDQANIEKMKKDAVLIN
                     VGRSEIVDKYAVMQALEKQHLAKYLTDFPEEEFLENDRILMLPHLGGSTQEALADSGR
                     LAVEALKDYLLFGTVREAVNYPSARMFFQAPFRFTIFYQKKTNILAEIFSLLNENELA
                     IADISRNHKNEHVYILIDIDSTDFEQLNQVKQQLEKISGVRKVRLLKKPERP"
     gene            complement(13107..14531)
                     /gene="araA"
                     /locus_tag="IXR40_000923"
     CDS             complement(13107..14531)
                     /gene="araA"
                     /locus_tag="IXR40_000923"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HAQ4360792.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(14547..15245)
                     /locus_tag="IXR40_000924"
     CDS             complement(14547..15245)
                     /locus_tag="IXR40_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HAQ4360793.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(15202..16863)
                     /locus_tag="IXR40_000925"
     CDS             complement(15202..16863)
                     /locus_tag="IXR40_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HAQ4360794.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKG
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            17081..18481
                     /locus_tag="IXR40_000926"
     CDS             17081..18481
                     /locus_tag="IXR40_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HAQ4360795.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKGLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIVGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(18733..19812)
                     /locus_tag="IXR40_000927"
     CDS             complement(18733..19812)
                     /locus_tag="IXR40_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAQ4360796.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(19898..20857)
                     /locus_tag="IXR40_000928"
     CDS             complement(19898..20857)
                     /locus_tag="IXR40_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HAQ4360797.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(20869..22392)
                     /locus_tag="IXR40_000929"
     CDS             complement(20869..22392)
                     /locus_tag="IXR40_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HAQ4360798.1"
                     /translation="MDEEVKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHE
                     TADGDGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIE
                     PNSFGLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQ
                     KKPFGVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPR
                     LPSYPEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFD
                     RQIEEIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMED
                     TLLFGSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAK
                     GQVLKQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLL
                     DQGEHYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(22402..22966)
                     /locus_tag="IXR40_000930"
                     /pseudo
     CDS             complement(22402..22966)
                     /locus_tag="IXR40_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
     gene            complement(22972..23835)
                     /locus_tag="IXR40_000931"
     CDS             complement(22972..23835)
                     /locus_tag="IXR40_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAQ4360799.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(23849..24745)
                     /locus_tag="IXR40_000932"
     CDS             complement(23849..24745)
                     /locus_tag="IXR40_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAQ4360800.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(24920..26191)
                     /locus_tag="IXR40_000933"
     CDS             complement(24920..26191)
                     /locus_tag="IXR40_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAQ4360801.1"
                     /translation="MKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTLTFWNGF
                     TASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFIALNYPD
                     FAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMYMYWNND
                     LFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLANGGKLV
                     NDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIEINGPWL
                     NNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFLKYWNTT
                     EIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQISAINNDI
                     INPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(26181..27698)
                     /locus_tag="IXR40_000934"
     CDS             complement(26181..27698)
                     /locus_tag="IXR40_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HAQ4360802.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            27896..28786
                     /locus_tag="IXR40_000935"
     CDS             27896..28786
                     /locus_tag="IXR40_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HAQ4360803.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(28859..29683)
                     /gene="nadE"
                     /locus_tag="IXR40_000936"
     CDS             complement(28859..29683)
                     /gene="nadE"
                     /locus_tag="IXR40_000936"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HAQ4360804.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(29695..31167)
                     /locus_tag="IXR40_000937"
     CDS             complement(29695..31167)
                     /locus_tag="IXR40_000937"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HAQ4360805.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(31804..32166)
                     /locus_tag="IXR40_000938"
     CDS             complement(31804..32166)
                     /locus_tag="IXR40_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HAQ4360806.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            32389..33141
                     /locus_tag="IXR40_000939"
     CDS             32389..33141
                     /locus_tag="IXR40_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAQ4360807.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWFSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(33281..34204)
                     /locus_tag="IXR40_000940"
     CDS             complement(33281..34204)
                     /locus_tag="IXR40_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAQ4360808.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYHKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(34219..34491)
                     /locus_tag="IXR40_000941"
     CDS             complement(34219..34491)
                     /locus_tag="IXR40_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360809.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
BASE COUNT        10231 a         7213 c         5979 g        11239 t
ORIGIN      
        1 caagaggttg tgagcctgcc gtttaactcc gagtcacaag gagcaatttc aaaaaacagc
       61 ttctcaggtt tgttgactat tgtgacttgt gaccgaggag ttggcaggag aacaccgttt
      121 aaggaagagg ttgtaaaatc agcggtttga cctgagtatt agagatacaa aacggaaaaa
      181 tagcttctca tattttgccg ttttttgagc taataccgaa ggacagctga ttgaacaccg
      241 tttattcgga aaaagggact gtgacacgac ttttgtcaca gcccctaaaa aaaataataa
      301 atttgtacta ttctatgaag cttcttcttc agaaaactga ctgttataaa gatctgcata
      361 gaatccgtct ttttccatca atgtatcgtg gtttcctgtt tctacgatcg aaccatgatt
      421 catcacaata atgttgtctg catcgcgtat tgtagacaag cggtgagcaa caacgaaact
      481 tgtccggttt tccaataggc ggttcatcgc tttttgaatc agtatttctg ttcgtgtatc
      541 tacactagat gttgcttcat caaggatcag gacatctgga tttgctaaga atgcccgcgc
      601 aattgtgatt agctgacgct gcccttgcga aatattgctt gcatcctcgt ttaatacagt
      661 gttatatcct tctggcaatt tacgaacaaa atcgtctacg tgagcagctt tagcagcctc
      721 aatgatttgt tcgtctgttg catcgtcgtt cccatatttg atattgtcat agatacttcc
      781 tgtaaacagc caagtatctt gcagtaccat tgaaaactgt gcgcgcaatt catcacgtga
      841 aagatcacgg gtatctacac catcgtaacg aatactacct ccagaaacat cgtagaaccg
      901 ttcaagaagg ttgatcagtg tcgtcttccc tgcaccagtc ggacctacaa tagcgaccat
      961 ctcaccaggt ttgacatcca agttaaaatc agtcattagc aagttatctg gtgtgtagcc
     1021 gaattgaaca ttttcaaaac gaactttgta tggtgtatct ttttcttctg gaaggccaga
     1081 tttttcattg gacatctctt cttcatccaa cacttcaaat acccgttcgg ctgaagcaac
     1141 tgttgattgg atagtgttca tcaaacttgc aagttgagtg attggttgag agaactgtgt
     1201 tgtatattgc aagaacgctt gaacatcccc taatgtcatg ttcccatttg caacttttac
     1261 tccgcctagt acagcgacga acacatagcc tagattttta acgaaattca tcaacggcat
     1321 gatgattgcc gaaataaatt gagctttcca accagcggca tacagattct gattttcttt
     1381 ttcaaatact tcctggtctt tttcagtatg attgaatgtt ttaacaatgg tatgaccacc
     1441 atatgtttct tctacttggt tattcaataa acctaaactt ttttgctgat ctgcgaaaaa
     1501 cacttgtgat ttcggcgcta cgatcatcac gatgatcaag cttaaaggga tcatcaataa
     1561 cgcgactaac gtcaattgcc agctgattga aagcatcatc acgatgaccc caatcaatgt
     1621 gactgcacta gttacaaatt gagtcaaatt ttgctgcagc gtgcttgcga tgttatccat
     1681 atcattgatt gctcgagaca tgatatcccc atttgtatgt gtatcataat aggaaatcgg
     1741 tacacgattc attttggctt ccaaatcatg acgtaattca taaactgttc gttgggaaac
     1801 acgtgtcata ataaattgct gtaaaaagtt gaatacagca gaaatcaaat acatcacgat
     1861 tactgtcgca atgatctgcg cgattttatc aaagtctatc ggaaattttg ttacttgttg
     1921 gccttgttgc atctgttgag cgccagccat tacacctttg aatatttctg tggttgcttt
     1981 ccccaagacc tttggtgttt ggatttggaa gatcacggct gctattgcta gtacaaatac
     2041 agcgatgatc gcaaccatac gtttagacat atagccaaac aatcggcgta ccgttcccca
     2101 gaaattttta ggcttttcac cttttacacc gagatttctg ccaggtccac catgtcctgg
     2161 accgcctgct ggtccatgag agggacgtgt gtttgtttta ctcatgctaa gtcctcctct
     2221 cttagttgtg aatgaacgat ttcttgataa gtttcgtttg ttgctaatag ttcttcatgt
     2281 gttcctttgc caaccagttt tccttcatct agcacaagga tcatatctgc atccattact
     2341 gtacttactc gttgagcaac taaaacggtg atactttctt tcatattcgt tttcaatgct
     2401 tggcgaagat tggcatccgt tttgaaatcc aacgctgaga aggaatcatc aaacacatag
     2461 atatctgctg ttttgactaa tgcccgtgca attgccagac gctgtctttg tccaccagag
     2521 aagtttcctc ctccttgttc cacatggcta tctaagccat cttccatctc tgaaacaaaa
     2581 tctttagctt gtgcgatttc taatgctttc caaatcattt catctgttgc atccggctta
     2641 ccatactgca tattgtctcg gatcgttcca gagaacagaa ctgctttttg aggaacaaag
     2701 cccattaatt ctcgcaaatt atattgagtc atgtcactaa tgtccgttcc atttatttgg
     2761 atcgaaccag attcgatgtc atataatcga gggatcaaat tgactaaggt cgttttacct
     2821 gaaccagtcc cccctatgat tgcgacgatc tcgcccgact tggcttggaa atcaatatct
     2881 tccaatgcaa gtttttctgc tccatgatat cgataattga catgattgaa ggccaatgtt
     2941 gcgttttttc cagcaaaaga aactgtttta ggattttcag ggtcatggat accgattttt
     3001 tcatccaaca cttcattaat acggtcagct gaagcttgtg cacgaggcac catgataaaa
     3061 atagcggaaa gcatcataaa gctgatcaag atctgcatcg cataagtcat aaatgcaatc
     3121 agattaccga cttccaaagt catatctgct atgtagtgtc caccaaacca agtgattgct
     3181 acgtttgtac cgctcatgat caatgtcatc attggcatca tcaatgcgac gatcgtatta
     3241 actttgattg ccgtatttgt ataatcttta ttcgctaaat caaaacgatt ttcttcaaag
     3301 cgtgtcttat cgaatgctcg aatcactctg acccctgtca atccttctcg aaataccagg
     3361 tttaaacggt cagttttctt ttgcatactt ttgaataatg gaacagcaaa gtacatgatt
     3421 ccgccgatca aaataatcat tactgggatg acaactaaga agatttttgt caactgatga
     3481 tctttttgat aagcaagtat gctcgcgcca atcaacgtga ttggtgcatt gatcatcata
     3541 cgtaaaaaca tttgtgtaac catttggatt tgagtcacat cattggtcgt tcttgtgatc
     3601 aaagaggccg ttccatattt atcaaacgca tcttttgtca gactctctga ttttttatag
     3661 acatccgtac gcaattgctt acccagtttc tgtgattcac gagtagcaaa aaatgtattt
     3721 gcgatagcag ctaagatact gatcaaagaa aagccgatca tcacaaaacc tgtatgccaa
     3781 atataatcga catctccttg cgctacccct ttatcaataa tattggaggt aagtgtcggc
     3841 aaatataaat ctgccagtac ttggatcacc atgaaaactg cagctgcaat tgctgaagtc
     3901 aaggagatcc gttttacgat ttttagcatc tagttccctt ctttctattt atatactccg
     3961 tttttcagcc aagaaagttt caaattgaat tcactgattg cttgctctac tgagtaatct
     4021 tcagatgttg aaaataagcg atacgaatgc gcaattgttg taaatacagt attcatcact
     4081 aattggatca gtaattccaa ttcatgatca ttttttactt tcagcttcgt ccgatcgatc
     4141 aattcaagca actcttttgc atcttgtttg tgttctttat gtggatcgtg aggcgttttt
     4201 tggcgactcg tatgaggagc gacttttctt gaggcacggt aatccatgtt cataaacaag
     4261 ttacgataaa aagaagcatt ctcgccttcc aaaatctcat aaatcatttt agaaaaatag
     4321 gattcgaatc ctttgaatag atcaccatcg gattctttca ttagttgtaa catatcttta
     4381 gagctgtcac gtctcattgt ctcaaagtaa taaaaataaa gatcctcttt atcttcaaaa
     4441 tactgataga aactgcctct agggatatcc gctaatttga cgatattagc aatcgaagct
     4501 tcttttaagg gtactctaga aaactcgatt ctcgcagcct cgattagtct tttttgtttt
     4561 tctttaggca aatggaaaaa tgtctgtgtc ggcatatgga ttctcctttc tttcaagatg
     4621 acacattgtc atatgacgct atgtcattat aacacctcct acctgttttg caagacattt
     4681 gcatagtttt tttcattatc atccgataca ttaaaaaagt gataagagga atccttccat
     4741 ttgaattaat gagagttgcc cattaaaata gccacatact aaacaaagga tgagataaat
     4801 ggcccaatca attagtgtcc aagacttcaa taaattgcct ctcgatgctg acagcatcgt
     4861 tttagataca agaaatacct tagattacac aaaaaaccac ttaagccact cgctttctat
     4921 ccccgctgct atcttgccaa gacaattaaa aaatctagat ccaaagaaac tttattatat
     4981 tctaagctat acaggcaggc gatcagaagc attagccgat caacttactg ctaatggttt
     5041 tcgtgctgtt tatatcattg gtgggatgga agctcttcag tcgagtgttg cttgaatatt
     5101 gcttgttaga ttcaaaagag gctgtgacaa aaaatcgtgt cacagcctct tttataccct
     5161 gtcttttttt agttatttat tcttcaacct tatcaatatg acttgatagc cttttctttt
     5221 tcgagtaaac tgattttgtt agtcatagtt ataacaatca tagcaataaa aggagaaggt
     5281 aagcatatgg catctgtttt agtagtcaaa ggtcatcccc taactgcaga agaatcgcgc
     5341 acagttaagg cattgacgtc ttttttaaca agttataaag aaaatcatcc agatgatgaa
     5401 gtgactgttt tggaacttta tcgcgatgat attccggaaa tcgatgaaga attattatca
     5461 ggttgggaag cattacgtgc tggtgcagaa ttcacttcct tatcagaaag tcaacaacaa
     5521 aaaattgctc gtttcaatga attgactgat cagttccttg ctgctgataa aatcgttatc
     5581 gcaaacgcct tatggaatct aaatatccca acaaaattaa aagcttggtt cgataccgtc
     5641 aatgtagctg gaaaaacgtt ccgctataca gaaaacgggc cagaaggatt agtgacaggt
     5701 aaaaaagcac tgcacatcca atctaatggc ggtgtataca acggacaaga ctttgcctct
     5761 caatatgtaa aaggtatttt aaactttgta ggcatcgatc aagtagatca gctattcatc
     5821 gaaggaatcg attatgaccc tgaccgtgca gatgagttga tgcaaaatgc attagataaa
     5881 gctgctgctt taggtaaatc attttaaaaa ttgagataaa tgcatacaaa agagacagag
     5941 gaaaaaatct tcaaagcagc atttgtgcct tggatatttt cccatctgtc tctttttgtt
     6001 attctttctg ctttttcaac ggattttctt cataaagaga agagattgtt gtgtaccatt
     6061 caaaaacatg agtaatcact actttagctg ctgcataaac aggaatcccc aagatcacac
     6121 cgatgattcc gaacaatttc ccagaagtca gcagaactaa taaaatcgtt actggatgga
     6181 ttgctaactg attccctagt actaatggag agatcaagcg tccttctatt gtctgctcta
     6241 ctgcaaaaac gatcagtact ttgatgatca tgaatggacc tgctacaatg gctaaaaaga
     6301 tagccggaat catcgctaaa aatgatccta agtaagggat caggtttaaa aaacccgcaa
     6361 taatccccaa cgtgacagca tactctaaac caatgaccgc aaaaccaatc ataaacatga
     6421 ttgccacagc aaaagccaca gttagttgtc ctcttatata agaagaaact tgactattca
     6481 tttcactcag cacattcaac gtcggttttt gcatgcgtgt cggtaaaaat ttgacaaaat
     6541 aaggtgctaa ttgtttaccg tctttcaata gataaaataa gataaacggc atcgtcagca
     6601 gagccactaa aatagtcgct accgcgccga caaaacttcc aagactctga actgtactct
     6661 tagatatatc ttggatcata tcgcctgccg aattcatgaa cttatcacct gctgtttcca
     6721 actgttcgcg aaattggttg aacagcgggt cccgcaaaat ctcggttaat ttattatcaa
     6781 tcgtatctac atattgaggg aagttactga tgaagctcac tgtttgttcc tgaatcttag
     6841 ggatgatcac tacgctcccc catgcgatta gtgcaacaac caaaacaaac agcccaatga
     6901 tactgtaaag ccttggtact tttcgctttt caaagtaatc aactaccgga ttcatcaagt
     6961 aatacaagat tcctgctaaa atgataggca gacctacgat tgctaaaaat tgccagattg
     7021 gtgcaaacaa atatgaaact tttgtaaata aaaagacgat cagcaatatt aacaatacaa
     7081 caagtaaggc tgtgactact tgattattta aaaaccagcg ccaaaaccac gataccggtc
     7141 tgttcttctt attttttcct tccataattc ctcctgttag ttataaaaaa tttggcttcc
     7201 caaaccaata gcaggcagtc tatgcggatg aagatagatt ccatttgcaa tttgtccttc
     7261 ttctggacaa gcatcaaaaa tcaatgatac gtgagctact gtctttaaat tcccattggc
     7321 catcggaccg acataatcga tcgtatatac ctgatcatca aaagcaattg ttccgcctgc
     7381 tttcaaagaa aaaggttcgt cttttgatac ttcttgaatc accgaatatt ttcgtaaggc
     7441 agctgttgct gttttatcga acaaaatcag catgggttct tccttgttta ttgcttctgt
     7501 cccaatttct gtaatctttg cctgaatcat tgcactctct cctttaattg ctttcaaaaa
     7561 cagtataaca cattctcatt ctttagccgt gtggaataat tatgtgatag aataaaaacg
     7621 aaaactattt cattacaatt aggaggaatc agctcatatg atcgaaaaga taattttagg
     7681 aacctatacg cgtcgcgaaa gtaaaggaat ctatacgatc gaccttgata cagaaaaaga
     7741 agaattagcc aacctttcat tagctgttga agaaaatagc cctacctatg tagcaaaaag
     7801 taaagctggc aatctttaca cagttactag tgtggatgga ttaggtggtg ccggtgcgta
     7861 cgataaggat tttcattttt tgaatgcggt aacagagtct ggcgctcctt tgtgttatgt
     7921 agcggttgat gaagcacgtc aattactata cggggcgaac tatcataaag gtgaagtaaa
     7981 tgtctaccat atattaggag atggcgaact gaaagcagca gattcaatat tccatcaaga
     8041 agcgacaggt cctcataaaa accaagatca tgcgcatgtc cactatacgg atctgactcc
     8101 tgaccaacga ttagtcgtat gtgatcttgg tacagatcgt gtgtatactt atgatgtgtc
     8161 cgaaaacggc aaattgaatc ttgtaactac cttcactgca gagccaggaa caggccctcg
     8221 ccatcttgtc tttcatccaa atggacaatt cgcttattta tttggtgaat tagacagcac
     8281 agtccgcgtg ctttcttata ataaagaaac aggtgctttt gaagaattac agaaaatatc
     8341 gaccttgcca gaagaattcg acggtgaaaa tggaggggca gctatccgca tttcaaatga
     8401 tggcaagttc ctttatgctt ctaaccgagg acataactcg attgctgtat tcgcagtttt
     8461 tgaagatggt tcccacattc aaaacaagca aatcatctca acagaagggg attttccccg
     8521 cgatttcgca ctagatccaa gcaataattt tgtcgtgtgt gccaatcaga acaccgataa
     8581 tctgacatta tatcgccgtc atcctgaaac aggattactg gaattactga aaaaagatgt
     8641 ctatgtacca gaatgtgtct gtgtttattt tgatcgttag taagaaaagg agaatgaaat
     8701 gaatcagcaa gacgtattag acagactacg ggaagaacta aatattcctt tctttgatgg
     8761 gaaaatcgaa gataaagagt atagcgaaga ggaatatcag aaactcaaag ccgatttaca
     8821 gaactacttt gaacaatatg tacagaatgt agaaaactaa tcagctttcc atactatctg
     8881 aaaagaacat caggacaaga cttttccgtc tatcctgatg ttcttttcta caaataaaaa
     8941 accgccgaga tggttagact cgacggaaaa ggagtattta ctcgattttg agtaagtaca
     9001 aggttgttgt tggttatagg tatgtcatta tcataaagga ttttgatcac tctatcataa
     9061 aggtaatatt acatttatat tagataactc tagtttttat tgttatcaaa gatttctttt
     9121 attttttcaa caacaaatta gtcatttttt ggatggcagc tgtcaattgg tctgtcgctt
     9181 ggtcttgttt tgcttcagat gtattgaata gatcttcatc tacccctgat tcaagatcga
     9241 tactttggat catttcttca cagcctgcta catatgaaag ataagctttt tcaaaatttt
     9301 tatgaatgcc cattgctttt gctggtggac gcaaagtact gactttcata agcattgccc
     9361 gatatttttt tgttccttct tcaaataaca ggatgatctc ttcaagagtc gatttgtcca
     9421 gttcacttgt ttttccttca tcaattgcgt ttctgatcac ttcatatttc ggatgcattc
     9481 cttctccgat tgcttctgtt tccttgacga tttgatcgat ggactgcaca taatagccaa
     9541 tattcggtaa catgttcgtt ttcctacttt ctccattgtt gttattattt attctacttg
     9601 tttttatcct caaatgacaa gtacttgaaa aaatttaatg gtttctatac agctcgccat
     9661 tcttattcgt gctcaaagaa accatctgct aaactatatt gtttccctgc gacaatgtca
     9721 tattggatca attgatattc gtcgtaaatc tcttgttgcg agcgattgaa ttgcgcttct
     9781 ttataccact gtccgttttg atagtacagt tctcgttcaa acgccggaag ttcctgttct
     9841 aatgataaaa gcagctgata aaagccattt gttgtctgat tcgtctgttc cattagattc
     9901 gctgcaaaat aaaacggact ggtgattgca tcgtgagtcg tttgcttttc taattctcct
     9961 ttactgtcga acataagaaa ttgtgtttca tgcaatgttt gtttgtcatt ttttgcttgg
    10021 atcgtatctg aatagatccc tggaagatga tccccccaaa aaacaactaa agtccttcta
    10081 gaaagattct tcaattcttc cgtgaactgc ttcagtgccg tgctgctata ggaaatatct
    10141 tgcagataat tctctaagtc aagtgtccca cttccatctg aagtttttgc aggatagtct
    10201 agattatcat actttccatc gtagggcata tgtgtctgca tcgtgactaa atgaatgaac
    10261 tgaggtgttt tttcttcctt gagaagtgtc attacttctt tgtaagctga ctcatcagaa
    10321 atatatggat tattctctat cgtatccgta taggtcatcg tacgctcgct gatgaactgg
    10381 tcaaatccta atgtctgata aacatcctct cttttataca tcgaagtatt gtatggatgg
    10441 atcgctgtcg tctggtatga ttgtgcgttt aacgctgaaa cgatagaagg aagctgatcc
    10501 atttttggta caagcatcgt gtaaggggtg gtgagttgcg cattaaataa cgccatagaa
    10561 aaaccagtca atgcttcaaa ttcgatattt gctgttccac cgccatagtt ttgagaaagc
    10621 atattgccac tatatgtttg atcagctact tcataataat ctgccaatgg ctcaccagat
    10681 acttctacgc cgtttaatcg actaggatct gagaaacttt cactcatcac gaacacgatg
    10741 ttcggcgact cttcctctac agttttattt ttttcatcgg ctagcttctg gtatttttca
    10801 gtgatttctt tgatcttttc tttcgaatat ccttcaggtt catccattgg ttctaccttc
    10861 agattgtaca aaaacccacc gataaaacca gtgttatagt agttcatttt ctggctgtaa
    10921 ggtatccata gtgccgtttt attatatgct tttcgcaaca aattatcggg attgttgaaa
    10981 ttactgatat accctagcag tccaattgcc acaagcagtg tcgttaatcg gatcaattgg
    11041 aatcgccttc cttttttcag gcttcgaaac atgtaccagc aaaacaatcc tatcacggtt
    11101 cctgcggcag ctaagatcac tgtaaacagc atagtgccgg tcatatcttt cagcaatccg
    11161 atttcagtga tcatcttcaa atcgtctgga taaatcggtt cttgccgata actcattttc
    11221 atataatttg caaaacctaa tacaccgatg gctacgacat acgtaaggga acctaaaggg
    11281 acagatcctg ctagtgcaat cagaaaaata agaataatca gcaagacgag acaggctaag
    11341 aagaattttt ccgtatgcca agaaaaagca aatttcaacg caaggtctac ggatagatca
    11401 ttttgacacc actgcaaaaa taaattacta aaaacaacaa gaaaaaagat actgatgatt
    11461 gctgctgttc cttttaaaat ctttttctgt ttggtcgaaa gtctgcttat atatcttttc
    11521 aaatgcttgc tccttcattt ctatcaataa aagaatgttg cttctcttat tttagttgta
    11581 cgaaattcga aagtaaagaa cggaaagaag aattaatgaa atccaaatat tctctttctt
    11641 tatggccttt ctggtttctt taataagcgg acctttcgta ctccagaaat tttttctagc
    11701 tgttgtttca cttgattgag ctgttcaaaa tcagtactgt ctatgtcaat caatatgtag
    11761 acatgctcat tcttatggtt acgcgatata tctgcgatcg ctagctcgtt ctcattcagc
    11821 agagaaaata tctctgctaa tatattggtt ttcttttgat aaaatatagt gaatcgaaac
    11881 ggcgcttgga aaaacattcg tgcggatgga taattgaccg cttctctaac cgtaccgaac
    11941 aaaagataat cttttaaggc ttcaactgcc aaacgtccgc tgtctgccaa agcttcctga
    12001 gtcgatcccc ctagatgagg caacataagt atacggtcat tttctaagaa ctcttcttct
    12061 ggaaaatcag tcaagtattt agccagatgt tgtttttcca atgcttgcat aacagcatat
    12121 ttatcaacaa tttcacttct tcctacattg ataagtacag catctttttt cattttttct
    12181 atattcgcct gatcgatcaa tccttttgta tcttctgtca acggcagcat gactacgatg
    12241 taatccgagg tagaaagaac tgtttctaaa tctgcttgcc gaacataatc caactgggca
    12301 tcgcggatag aataacccaa gacatccatc cctaagctat agcaacttag cgctactttt
    12361 gtgcctatcg ctccaagacc aagaagaccg atggttttgc cttgcaattc tcgtcccaca
    12421 taagcacttc ttttgttttc tgcctgttct aaaatattag gacctgttag tgtttgtacc
    12481 atacgacttg cttcgattat cggacgggaa gataagagca aacagcacaa aacaagctct
    12541 tttactgcat tagcatttac acctggtgta ttcatgacga tcgtcccgtt ttcagaagct
    12601 ttttcaacgt tgatcgtgtt caccccaaca ccagctcttg aaattgctag caaatctggt
    12661 gtaagccatt catctttcac tttcgtacta cgaataacta ttccttcggc tggcaaatca
    12721 tctattattt tgaaatattc cccttgtaac ttttctatct cttgttctgg aatagcatca
    12781 atcaaatgaa cgtgatacat aaaaccccct ccttactaac aagtatctcg aaatttctgc
    12841 aattagacaa ctgtttacca tttgacttcc tagaagcaaa aagagcagtt agagcagagt
    12901 aggctgagtg ataaaaataa ggctatgaca agttactgcc ataagcctta ttttcgagag
    12961 caaaatattg agggtgagat atcttgataa atggtgttcc gttagctgac attgataata
    13021 agactaaatt tcaaaaaagt tgaaaagcaa atttcgtcaa tctcttctta tttcttaaaa
    13081 ctaagtggct ttttcacaac ctctttttat ctaataacca ctgtttccaa ctcaactaat
    13141 tttgcccacg tttcaatttg atctgttgtt agatttagcg agacaacggt atgatgaccg
    13201 ccacctgcct gaatccatga atggacacct tcatggaaat tcggtttagt tttccataac
    13261 acacgtgcaa caggtaaatt aggtgcttca gtcgttggtt caaaggcttc tacttcattg
    13321 atcagcagtt tataatgcgt accgaaatct gccatcgata cgactacccc ttctcctgct
    13381 ttcccatcaa atacaagacg cgccggatct tctctatctc ccattgataa aggagaaaca
    13441 acgattcttg gtttcgtcgc agcaagcgtc ggatctactt ccatcatatg ggattccaag
    13501 attgcttctt ggccactagc tagctcgtaa gtataatctt ccatgaatcc tgtatctttc
    13561 cctcgagcca tgattttcag caaccgatca atcgctgcag ttttccagtc gccttcccca
    13621 gcaaaaccgt atccttctgc catcaaacgt tgtacagcta gtccaggtag ttgtttcatt
    13681 ccatacaggt cttcaaaatt agtcgtaaaa gcgttatagc ctccttcttc taagaaacgg
    13741 cgaataccga tttcctgctg agcttgtact tttacatgtt cctcccatgt cttttcttca
    13801 taatcaccat agtcgaaggt atacaattcc ttgtactctt caaataattg atcgacttct
    13861 tcgtctgata cgcgatcgat tacttgtaca agatctccga taccaaaata atcaacagtc
    13921 caaccaaatt gaatctgtgc ttccactttg tctccttctg tgacacccac gtttctcatg
    13981 ttgtcaccaa aacgagccac ttttattcca aaactttcat tataggctac tgcaacatcc
    14041 atccaatcag caatctcttt ttggatctca ggtcgtttcc agtagccaac gacgatttta
    14101 ttttgtttat ttaatcgagc attgatgaac ccatattcgc ggtcaccatg agcggattga
    14161 tttaaattca tgaaatccat atcgatcgtt ttccaaggaa tgctttcgtt atattgcgta
    14221 gctaaatgaa gcaatggttt ttgtagaagc tttgtcccgc ggatccacat ttttgctggt
    14281 gagaaagtat gcatccaagt gatcacacct gctacttctt ctcgataatt gacctctttc
    14341 atgatttttg tgatcgtatc agcagtaact gctaattctt gaaggcggat tggataaggc
    14401 aattggccat tttcattcag ttcatcgacc atttcttgtg catgtttctt tacttctcgc
    14461 agtgcttctt ccccatataa atgctgtgat cctacaacaa accaaaattc tttttctcca
    14521 atattcaaca taattagcca ctccttttat ttgttttgtc cgtaatacgc attttttccg
    14581 tgttttcgta aataatgttt atctaaaatc cgttgaggca gctcttctga aaatgaattg
    14641 agctgtctgg taaataaatt catcttgcat acttcatcta gtacgactgc gttcattacc
    14701 gcactttgcg catctttccc ccaagtaaat ggaccgtgtc cgtgtaaaag tacccctgga
    14761 attgctaagg gatcaatttt gcgttctttg aatgtttcta tgataacttt tcctgtttca
    14821 tattcgtacc cgctgtcgat ttcctgttgt gtcaaaaatc gagcacaagg taccgatcca
    14881 taaaaagtat ctgcatgcgt cgtccccatc gcaggaacat ccaatcctgc ttgtgcccag
    14941 atcgtcgccc atgtcgagtg agtatggacg attcctccga tttgaggaaa tgaacgatat
    15001 aaaacagcat gagtaggcgt atccgaagag ggattgagtt taccttcaat gatatgattg
    15061 tccaagtcca caacgaccat gtcgtctgct gtcatctctt cataactgac tccgctaggt
    15121 ttgataacga aatatcgtgt ttcaggatca aaagcgctca catttcccca tgtatatttg
    15181 acgagtccgt gtttaggcaa gtcaagattt gcttggtata cttcttcttt cagttgttcc
    15241 agcattttct atcactcctt tttcttgcaa ttgatgaatc gctgtttttt caatgtcgat
    15301 cccctcacgg taacgtctca taaatatctg atagcctgct atttcttctg ctgaaggtgt
    15361 gatggtgatt ccttggtctt gtccaaacac gtcttctgcc aagaagtttt ctaaagactt
    15421 cccatgtcga tccatcatat aggctgctaa taacgcgatt ccccacgctc caccttctcc
    15481 ggctgtgtcc atcactgtaa ctggtgcctc catagcagat gctagaatcc gctgtccaac
    15541 ttctggtgtt ttaaaaatcc ccccatgccc cactaaacga tcaatttgga cattctcaga
    15601 tttcaatata tccattccga ttctcattgc accaaaagca ctggctaaat ggatccgcat
    15661 gaaattcgct aaatcaaaac ggctacctgg tgtacgtaca aataatggcc ttccttcatt
    15721 tactcctgta atgttttcac cggaaaaata accataagaa agtaatcccc cgcaatccgt
    15781 atcgccttct agcgctttgt tgaataatac cgtgaataat ttatctctgc ttatctccat
    15841 acccaaagaa ttggtaaatt cttcaaaaat actgacccaa gcattgatat ccgaagagca
    15901 gttattcgta tgaaccatgc ctactagttc tcctgaaggt gtagtgacca tgtcgatttc
    15961 cggatggaca ttttctagtt ctttttctaa tacgatcata gcgaaggcgg aagtaccagc
    16021 cgaaatgttc cctgtccctt tggctacact gttcgtagcg accataccgg ttcctgcatc
    16081 cccttctggc ggacaaaccg ggattcctgg tctcaaattt cccgtagggt cgatcagata
    16141 agcccctgat tcgcttaact tgccagcttc ttctcctgct actagaactt taggcaaaat
    16201 gtgatccaag tcaatcgcta cgtgcgcttt ttcgattaac tgaccaaaaa tatttttcat
    16261 ttcttgatgg taggttttcg ttgaaggatc gataggaaac atgcctgatg catctcctac
    16321 gcctagtact ttctcaccag taagctgcca atggacataa cctgcaagcg ttgtcaaaaa
    16381 attaatttct ttcacatgtt cttctttatt caaaatagat tgatacaaat gagcgatact
    16441 ccatctctgc ggaatattgt attgaaattt ttccgttaat attcgttctg cttcttcagt
    16501 gattgtattt cgccaagtac gaaatggtac tagtaactgt tccttgctat caaatgctag
    16561 ataaccgtgc atcattgcac tgaacccaat cgacccgatt gtcgtaagat tctcgccata
    16621 gatttcgaat acttctgctg ccatttttcg gtaactgacg cgcagtcctt tccaaatatc
    16681 ttctaatgaa taggtccaga taccattttc tagtttgttt tcccactcat aactaccagc
    16741 ggcaatagga gtaaaagatg aatcaatcaa tacagctttg atcctagttg atccaaactc
    16801 aatccctaaa gatgtacgac catctatgac atctaacata ctttgcgcat ttacttcctt
    16861 cataatgatt taactccctc cttctcgtca aacctgatca aaccgtcttt ttagtagcgc
    16921 ttacaatgat tattgtatac ttttgtacgt acatgtcaag cagttattta caagaataca
    16981 ataaaaaaca cttgttttgt acgtacataa gttataaaat gaaattgctt acaaaatctg
    17041 atcaaccgcc ttctcgaaat tctagaagga gagaatactt atgaaaaaag aaaaaaaagt
    17101 ttcctcatcg tttatttatt tttttggcgc atttggcggc attctatttg gatatgatat
    17161 tggtgttatg accggcgcct tacctttttt acagcatgat tggggtttgg caggtaaagc
    17221 ttctttgata ggatggatca cgtcttcggt catgttaggt gcgatccttg gcggctcttt
    17281 atctggtctt ctttctgata agcttggacg acgaaaaatg attcttcttt ctgcacttat
    17341 ttttatggct ggttctgtcc tttctgcatc tgcccctcac aatggttctt attttctgat
    17401 tgcagcaagg attcttctag gtttagctgt tggcgctgca tctgccctag ttcctgctta
    17461 tatgtctgaa atggctcctg ctagactaag gggaagattg tcagggatca atcaagtgat
    17521 gattgcttct ggcatgctcc tttcctatgt tgcagattat ttgctaaaag ggttgcctga
    17581 aacgatggct tggcgcgtga tgttagggct cgctgctgtc cccgcgctga ttttattttt
    17641 cggtgtttta gctctaccag agtcaccgcg ttttcttatg caatctggcc gcttggaaga
    17701 ggcaaaaaga gtattgaact atattcggac accaaaagaa gctgaacagg aattcgaaca
    17761 aatccagctg aatgtcaaac aagaaaagac aaccggaact tcttggcata ctttgttttt
    17821 agaaaaatat cgttccttag tcattgccgg tattggtgta gcagtattcc agcaatttca
    17881 aggagctaat gctatttttt actatattcc gctgatcgta gaaaaagcga ctgggcatgc
    17941 agcgagcgat gcattgatgt ggccgatcat ccaaggaatc attttagttg ctggttcttt
    18001 gctctttttg gttattgcag acaagttcaa tcggcgaact ttattgaaaa taggcggtag
    18061 cgtgatggga ctttctttca tcctaccagc tgttttagga actgtactgg atgctcatac
    18121 aaattcgttg ttgattctct tgtttttatg tatttatgtc gcattttatt cttgcacatg
    18181 ggctccactg acatgggtaa tcgtaggcga aatattccca ctagctgtcc gcgggcgagc
    18241 atctggccta gcctcttctt ttaattggat tggttctttc ctagttggct tgctttttcc
    18301 tgtgatgact gcttctatgt ctcaagaaat cgttttcggc atttttggga tcatctgctt
    18361 tttaggggtt ttatttattc aagagatcgt accagaaact cgtgggaaat ctttagagga
    18421 aatcgaacaa agtgcatcta aaaaaactta tcctaaacgt atttctatcc atcattctta
    18481 aagaggttgt gacagaagtg gtcagcttca agaaataaga aggaaccgct tagtttccag
    18541 tcacaaggaa caatttcaaa aaacagcttc tcatgtttga tgaatattgt gacttgtgac
    18601 cagttggtag gagaacaccg tttagtggag aggtggtgaa agaaacgttc agccttgagc
    18661 gatgacaaaa gctctcacaa acattgcgac gagtaaccgt aggagcaata agaggcggta
    18721 aaaacccgtc tcttattttt cgttttcttt cactgtttcc cgttcaacta gtacaggttc
    18781 atagagaata tttggctgtg cctgtccttt ttcaatcgtt gtgacgatcc accgtgcggc
    18841 atcttgtccc aacttttctt ttggatgcgt caatgttgtc aattttttat tccctaaatg
    18901 gcttaaagaa gaatcgtctg ttcctacgat cgataggtca tctggaatat gatagccatt
    18961 ttctgtcaac ttatctagca ttaaactagc tatttgatcg ttatagcaaa tgatgccatc
    19021 taaagcttgt tcttctttca accgttgtac tgttttttca gcgattgttt ctcgtgtttc
    19081 cgtggtgaaa gtaatgatat cttccgtcaa aaaacgcaca ttatactgtt cacacgcgct
    19141 gataaaacct ttcatcctgt attttccttg aagatcgtcg atttttgtga tgaacaacag
    19201 acgctgatgt ccttttttta tcaaatattc tgctgccata aaaccgactt tcacatcatc
    19261 taaacaaata taagaggcat ttaactcttc ataagcagca ttgatcatca ccatcggaat
    19321 gccttgttct ctcaaagcaa cataaagtgc taagtttggg ttatactgat tacttttcgt
    19381 aggctcaacg atcaaaccat ctaccccata agcaatcatt ttcttcaaac actctttctc
    19441 caattcgtga tcgttattcg tactggctaa aagcaatgaa tacccagatt ctcgtaattc
    19501 attttcgatt cctcggataa tcgacggaaa aatataatca gagagatatg tggtgatgac
    19561 accgatcgtt tttgttctgt tcaatggtgt tttttctttc ttatagctgt catctacata
    19621 tgtgcccgac cctttttctt tacgcagata gccctcattt accaacacag cgattgcttg
    19681 ccgaatcgta tgtctgctga cgtcatatat ttcttgcagc ttgaattctg agggaatggt
    19741 tgtatttact tcgtattcct cacgaaggat cttttgtttt atctcttctg caatatcttg
    19801 atattttgcc atttgccttg ccccttttta tttgtacgta catatatcat aacgagtctg
    19861 caaggtttat tcaagcaaaa atcaaggttt cttgtgctca taaggcatac ggaacaggtt
    19921 caccaaattc tggaaatcct tgctcattcc acgtaaagca ttgcgcgttc gcgtgccgat
    19981 taggattgtc taacggatcc cctttttggt tcttctctgg tcgagcatga tagatcaaaa
    20041 tatcaaagca cccgtcttct gaaaccgtaa acgagttgtg accaggacca aattgcttat
    20101 ttttttcaga agaaacgaat actggctccg ataatttatg ccatgattct tttaataaaa
    20161 gattcttgtg ctcatcagcc cacagcaggc ccatggcata gttttcatct gttgcactac
    20221 cagaatacgt aatgaatatt ttcccattgc gagtaaggac tgctggacct tcatttactg
    20281 aaaaaccccg tttttcccat tcatactcag gtatagaaag gaggatctgc ttccccttta
    20341 acgtccaagg attatccatt tcggatagat aaagattaga attcccagta atttcaggat
    20401 cttgttgggc ccacacataa tatagctttc cttgagaaga gaaagttgtt ccgtctaaac
    20461 tgaaagtttc ccttttcgtt tttatttgtc ccttttctat ccaatctgta ttcattggat
    20521 ctatatgctg attttcaagt acgaacatgc ggtgatgatg agattcatca cgtatagttt
    20581 tatgattgct tgcagcaaag taaatatacc attttccatt gatataatgg acttcaggtg
    20641 cccagatcaa ttcactcatc ggtccttctt catgagcctg ccatacaatc aggcttgcag
    20701 catgttctaa ttcattcagt gactttgccc ttcttaattc aatcacttgg tagcctggaa
    20761 ccgatcctgt aaaataataa taaccatctg tatgtttata tacccaagga tctgcccgtt
    20821 gccgaacgat aggattatta taaagtgtct tcatcataac aaatttcctc acattttctt
    20881 tattctaatt acattccaag agtatttttc tatccctaca tttaattcgt catgtttttc
    20941 tattgaaaaa tagtttattt caggttttat tttttctggt tcttcacgtg tatttttgtc
    21001 caacagatcg ctactggtta atgtgtagtg ctctccttga tctagcaaat tgaaatcatg
    21061 ttcaatcgtt atcttttgtt gttcatttgt gcgattgatc aagaaaatag tcagctgatt
    21121 gccgttatct acgatcacac tgtccacata aggaacattt tttatctttt cacaatcata
    21181 aacagggcaa atgatttgtt gtttcaatac ttgaccttta gcatatttcg ataagtgttg
    21241 catcacataa taagttggat tcctccatgc ttgtccttta gcatctgtca gtattaaagg
    21301 tattgtgttt actaacaatg attgacaact aatctttacg cgatctgcgt gtcgtaaaat
    21361 agccagccct aatgaaccaa ataataatgt atcttccata gtaaagtaac accaatcgat
    21421 gggactaccg acttcaaaat ccctatgtct tttttccggt tgggcatgta cattccattc
    21481 atcaaacgct agatacattg ttttctcact tctcaaatat ccttttacat aatcacaagt
    21541 agcaacgatt tcttcaattt gacgatcgaa tcgataagct tttgcaaggt atgtcgctgt
    21601 atcatcacgc tcatttttag gaggtttagt caagtcttct tcatcatact tatcaatata
    21661 gttatgcaaa gctaaataat ctacattctc ataagcttct tctaatgcga tacgatccca
    21721 ttcagggtac gatggtaaac gtggcgtaga gcttccaact aagattgttt caattgaatc
    21781 atccactaac ttcatgactt ttgaggcttc atttgctaac ctaccatatt cataagcact
    21841 cttagccccc acttgccatg gaccgtctag ctcattccct aaacaccata atttaacgcc
    21901 aaaaggcttt ttttgcccat tttttattct taaatcactc cagaaggttc cttttggaaa
    21961 attacaatat tctactaaat tttttgcttc atcaattcct tttgttccta aattcaccgt
    22021 gaatatcggt ttcgcttgta catgactgat ccatttaaaa aattcgtgga gtccaaaaga
    22081 atttggttct atacctcgcc atgctaaatc aatttttttt ggtcgttgtt ctttcctacc
    22141 tacagtatcc acccaatcat aaccagatgt aaagtttcct ccaggatagc gaatgacacc
    22201 taattctaat tcctttacat aagagaggac atcttgtcta aacccgtcac catcagctgt
    22261 ttcatggccc ggttcataaa tccctgtata gacgacactt cccatatgct caacaaatga
    22321 gccaaacagc cgagaactga tctctcctac cgtaaaatcc tctctgattt ttactttcac
    22381 ttcttcgtcc aacagctttc cctacctttc atttcctata gtcaagataa tagatacaag
    22441 tttccatacg ccaccagcaa agataaaaat aaaaggaggg aaaagaaata tgagcagtac
    22501 aaatcctaat aacaatacgc aacaaagaat atttctcaaa aaatcaaaaa atactttcca
    22561 tgcactttgt tcaaaaattt gtaaaaatgt gatatctttg ttttcagaaa tcacatatat
    22621 ccaggataaa agaaacatgg aataaataag taaaactaca tatccactaa ttgaaagtac
    22681 gattgtctgt tcttctaata attgattaac aagaaaataa ataatgatcg ttaacagact
    22741 aaggaacaag ttcttaccaa aatgttgctt tattccttga aagaaaaaat aaatgatatt
    22801 tcctgatccc tcacctttcc attgcgccat tacataaaaa aacagcacat gtagcaggca
    22861 cgatagtaat aacaggcaaa cacacgatta cccagagaat acctaataag atgtaatcag
    22921 aaaccacaat caactgtcca taaagtttag tctcaactat tttcatcttc ctcactcttt
    22981 cattccagac atagctgttc cttgaacaaa atatttctgt gcaaaaatat aaaccactag
    23041 taatggcagc attgaaataa ccgttccagc cattacaggt ccataaaaag aaatgttctg
    23101 ccctgtaaat aaagctaacc ctgctggtaa agttctcatt tttgaactac ttgtcaatat
    23161 caatggataa agcaagtcat tccaactatt catcagcgtg aaaatcccta atgataaaag
    23221 agtaggtttg ctcaatggca acatgatttt caaaaaaata ttaaactcac ttaatccatc
    23281 aatgcgtgct gcctcttcca aagaatctgg taaagtaata aaaaaggaac gcatcatgaa
    23341 gataccaaat gcagttgtca tacgaggaat gatcaaacct gcataagtat caagcatgcc
    23401 aagcaaattg acttcaataa atagaggaat catgaagact tggaatggga tcatcattgt
    23461 cagcaaaacg aaatagaaca aaactgattt tcctttgaaa cgcatacgag caaatgcata
    23521 ccccgcaaga gaatcaaaga atacagaagt gatcactgtc cctccagcaa aaatcactgt
    23581 atttttgatg taatctaata aagggatcgt tgtccaaacc ttaatatagt tatctagggt
    23641 atagctatct gcaaatattc taggcggaaa tgagataatg tctttttcgt gtttaaaaga
    23701 agaaataatc agccacaaaa aaggaaacgc aataaccaac aatataacta gcatactaat
    23761 cgttcgaatg atttttttac cactaactgc ttttcgacta ttcacagtaa ctgtaatcga
    23821 gctttctggt gccatacagg tttccctcct atttcatttg tttttctttc cgtgacatgt
    23881 acacattagt ggagatagct atagttgcaa caatgataaa caaaaccgaa gacagtgctg
    23941 atgcatagcc caattcataa ggtgctgtaa atcctcgact gtaaatatat tgaacagctg
    24001 tttctgtctt aaattgtggg ccaccagcgg ttgcaacata tacttggtca aacacttgca
    24061 tcgaaccaat cagattcgtt aaaatacaaa aacctaagga gggaacgatc tgaggtagcg
    24121 taatgttaaa aaactgctgt cgatttgttg caccatccat ttgagcagat tcatacaaag
    24181 agggagagat tccctgaata gcagtcaaga gaatcgtcat agtaacacca aaattcttcc
    24241 aaacagtcat gatggctacc gtcggcatag caagggttgg atcgcgaaaa aattgaggga
    24301 tcggcaagcc gacttgtgaa aacaagtaag gaatcgcccc tacattcgga tcaagcaaca
    24361 tagaaaaaat aatcgcaatt gacgtcaatg aacaaataac tggaatgtaa aatgtcgaac
    24421 gacaaaaacg attgaatctg gtatttttag ataatgctac tgctgctaat aaaccaacga
    24481 taatttgtgt tggcgtttcg agtacggtga aatataaaga atgaatcaac gaattaactg
    24541 ctcgttcatc actaaatata cgtgtgaaat tttcaaaact tacaaaattt cttgatgtaa
    24601 agaaaatatt caaatctgta aaactaatag caaatgttcc taaaagcggt atgacagtaa
    24661 ataataataa aactaaaaaa gatggagtta aaaacaaata cgcagcacga tcaggacgat
    24721 tccaatattt ggtgaatccg ttcatatagt ccacctcatc tttcattttg ataaaatata
    24781 caatcttggt ttaaacgaat ctgaataaga tatccgaaca atcgctgtga tttttgcaat
    24841 aacacctatc tgcaaatact aggtcgatca ttcagatatc tgtatcttgc caacagtcta
    24901 tcctgtataa agttctgtac tatttttgca gtaattgatt gatggcatca tctgcatcgt
    24961 tcatgagtgt ctcaggatct tctcctgcta ataatttttc aatcagtgga ttgatgatat
    25021 cgttattgat cgcagagatt tgggtaaaac ctggtaaata tggctctgca tagtccattt
    25081 gtttcgataa ttcagataca ataggatcat tttttacttc ttcatctttt gctactgaat
    25141 ccaagtaggc aggaaaacca ttttcgatac tccatttttt accaatttca gttgtattcc
    25201 aatatttcaa aaactcatag acagcttctt ttttattatt atctgtactt gccggaatgg
    25261 catatcctac gccatctaaa atagctgttt ttttgtctga atcactccct tgtggtaagg
    25321 tagtcacatt ataatcaatc tcgtttgctt tcaatccgtt atttaaccat ggcccattga
    25381 tttcaatggc tagttgacca gcattcatta aattgtccat ttcggcgcca gaaatcgatt
    25441 ctggaccagt cttgtctaca tggatcattt tttggatcgc ttttaacgtt ttaaggttct
    25501 caggagacgc aaattcagac ttagtataat catcgttcac taatttaccg ccatttgcta
    25561 acatccagtt atataacggt gcagttccat ccttattgaa gacaaaacct gatacatttt
    25621 tactactatc agttaatttt ggtgccattt ctgtcaattc ttcccaagta gtaggtggtt
    25681 gttcagtatc taatccagct tgtttaaaca aatcattatt ccaatacata tacatgcctt
    25741 gtacctgcat ggggacaaaa tactgtttac cttctacttc acctaattca atagccgttt
    25801 ctttaaaatc agatttatct actccatcat attcccagaa atcgtctaat ggttgtaccg
    25861 ctccgttttc tacatactgt gcaaaatctg gataatttaa tgcaataaag tcaggtgctt
    25921 ttttagaaga aatcgctgta ggaagttttt cattcaaatt ggcccaagtc atgatatcca
    25981 tttcaatttt gatgttttta tcatttgttt tattaaattc attaacgatt tcttgcaata
    26041 tttcaccatc agatgcagta aacccattcc aaaaagtcaa agtcacttct ttatcagaat
    26101 cagattctgc tgaacttccg ccaccgcaag ctcctaaaat acctgttgca gctaccaaca
    26161 aagagccaat taaccatttt ttacctttca ttttttgttc ctccttcatc tgataaacga
    26221 catctgacca cattccaaga tagcggtttc aataaacaat tgattttccc atcttcagct
    26281 tttacatttg ttgaatgact tggttttact tgttcacttt taggaagatt agttgctttt
    26341 gtatcaaatc cactcatttc agaaaaatca atcactccct ctaatgataa ttcagacaag
    26401 tgaacagtta gattcatttc ttcttctcca cggttaactg caaatatgac aagttctttg
    26461 tcatttatta cggctatact ttctaaatac ggcacttctt caaaatcttc cgtcgcatag
    26521 tttgctgaac gaatttgtgg gcttaacacc tctccttgtc catacacagc agcttgcata
    26581 aatggataat agatcgtctg tctccaagct tctccgtttg tttctgtcct gattggtgca
    26641 ataacattta ccaattgagc aagacaagca atctttactc tatctgcatg tttcaataaa
    26701 gtgattaata gacagcctaa tagtaatgca tcttcaaaat tatagttatc ttctagtaaa
    26761 ggaggagcaa tctgccaagg cgctgcttgc tcatcttgtt ccgctgaatg ataccaaata
    26821 ttccattcat caaaggacag gttgatctgc ttcttactat gtttcttcgc cttgactgta
    26881 tcgcacatcg ctgtcacttc agaaatgaac cgatccatgt ctaaggaacg tgcaagataa
    26941 tgagaaagat catttttttg gttgccataa tattgatgca gagacaaata atctatttga
    27001 tcgtacgctt gatcaagaac tgttaactcc caatcaccaa atgtaggcat ttgccgattc
    27061 gaacttccgc ataaaaccac ctcaattgaa tcatctacga gtttcatcgc cttagccgtt
    27121 tcctctgcta accgtccata ttcttccgct gttttatgtc caatctgcca aggaccgtcc
    27181 atttcattcc ctaaacacca tgtcttaatt ccaaaagggc tctcttgacc attcgaacgc
    27241 cttaaatcac tccaataagt tcctttagga aaattacaat attcgactaa attacgagct
    27301 gcatctactc cacgagtacc cagattgaca gccatattga tttcggcccc cacatgctga
    27361 caccagttat aaaattcatg aatcccaact tcattcgttt caattgtccg ccaagctaaa
    27421 tccaaccttc taggtctatt tgctatgggc ccaatactgt cttcccaacg aaatcctgac
    27481 acaaaatttc caccaggata tctaatcatg ggaatgttca attcttttac caagtgaatg
    27541 acgtcttggc gaaatccact tttattagct gatggatgat ctggctgata aatcccttca
    27601 tatactgctc gtcccatatg ttcaataaat gaactgtaca accgcggatc aactttgcct
    27661 acacgcttga cactactaat caacattgtg gcttccataa ctgacctcct ttaatttata
    27721 catgaataat acacctcgtt gaaagcgttg tcaataatat aaatgttaaa cttacttatt
    27781 ttttatcgat tttaattaac caaaatatta ataatgatta aaacaaataa tttaatataa
    27841 cttttattaa caaatatgtt aatatataag aaaaaccttt taagaggtga tatatatgca
    27901 actacaaata aacgaagaat ccttaccggt atatgaagca ttagctagta aaacaaggat
    27961 caagatcatc cagctacttt ccaaaaaaaa gatgaatgtc aaagatttgg caaaagaact
    28021 tggagtgagc agtgctatca cgacgatgca cgtgaaaaag ctagaggaag caaacatcat
    28081 caaaacagaa aaagtaggac aacaaaaaat ttcgagcctt cgtgtcgata aaatcgatat
    28141 cagttttcca gaaaaaatat tcaatgcttt tgatacgaaa gaaacatcga tacctattgg
    28201 tcactataca aattatgcaa ttgaaccaac atgcggttta gctacgatcc atgattttat
    28261 cgggaaagtg gatgaaccac gctattttat ggatcctcga aggatggatg cccgcattct
    28321 ctggtttacc agcggatttg tcgagtatca ggcacctaat tttttaaata cagaggatac
    28381 attggagatg ttggaagttt ctgtggaaat ttcttctgaa tttccttttt caaatgacaa
    28441 ttggccttca gatatcactt tcagcctaaa tggtgtggag ctaggaacat ggacgagccc
    28501 tggagatttt gctgatatcc gcggtaaata tacgcctgat tggtatccag ataatcttaa
    28561 tcaatacggc ttgctgaaga cgatccgaat taccaaacac ttgacgaata tgaatggaga
    28621 acccttgtca aacatcacga tcaacgacat ccctaaagag caagacactt ggcatttgcg
    28681 aatcgaagtg aaagacgatg ccaaacatgt ggggggctgt actttatttg gtaaaggatt
    28741 cggtaattac gatcaggata tcaaattaaa agtttactac agctgatatt tttcttttct
    28801 attttataaa acaaaaacag ccaatcccta tgaagggacg gctgtttttg ctttattgtt
    28861 atttccagaa atcatccaaa acggaaattg gcaaatgtcg tttatgttgt gtcttgttcc
    28921 accatgcttc gattttttct tgtgcttgag cgggaacttc ttttccttct agataatcat
    28981 caatttcatt atatgtgaca cctagtgcga cttcatctgc aatcattggt ttcccatctt
    29041 caagatctgc agtcggaatt tttgtgtata atttttccgg tgcattcaat gcttgaagca
    29101 attgtttccc ttgtcgtttg tccaaacgga ataatggcaa aatgtcggct ccaccatcac
    29161 caaatttcgt gaagaatcca gtaatgtttt ctgcagcatg atctgtccct aatacggctc
    29221 ctgctctttc tccagctacg gcatattgcg taatcatacg ttgacgtgct ttgatatttc
    29281 ctttgttaaa atcgctgatt cccacacctg cttcgcttaa tacttgtact tgtgcatcaa
    29341 cagctggttt gatatttact cgcagactaa catcgggctg gataaagtca agagcagctt
    29401 ttgcatcttc ttcatctgct tgttcaccat aaggaagacg aacagcgata aattgatagt
    29461 tttcatcttt tgtttcttca cgcatttctt ccatcgttag ttgcgccaaa cggcctgcta
    29521 aagtagaatc ttggccgccg ctgataccta gtacaaaagt tttaagaaac ggatattttt
    29581 tcaaatatgc tttcataaag tcaatacttt tacgtatttc ttcttttgga tcaattgttg
    29641 gtttgacacc taattcattg ataatttctg tctgcaggct catttattct cctcctatgc
    29701 ttctgtatga agttctgcta cgcttttttt cattcgttcc atgatagcca ttttatggtt
    29761 ccagcattca gtagacagat cgactgggta tttttgcgga ttcaagtctc gtttatactc
    29821 ttcccatagt gaatctagat tttcttttgt atattctttg atttcgttta gtgcaggtaa
    29881 ttcgtaaact ctttttcctt cgataaagat atcttgtaaa actgggcgag ctgtaaagtc
    29941 tcgaacagtt ttattgataa acgtatgcac tggatggaac atgaagatag cttcttcttc
    30001 tcgagggtct tcatcccata atgtcacgta gtctccttca gatttcccat caaaatttcg
    30061 agtgatgcgc cacacttgtt ttttccctgg agtagttact ttttctgcat tgcttgataa
    30121 cttgatcgta tccatcattt ttccttcatc atcttcgatc gatactagct tgaatactgc
    30181 accaagggct ggctgatcat aggctgtgat caattttgtc ccaacacccc atacatcaat
    30241 tttagctttt tgcatcttta aattcaaaat cgttgcttca tccaagtcat tcgaagcata
    30301 gatttttgct tccgtaaatc cggctgcatc taattgttcc cgaacacgct tagatatata
    30361 ggccatatct ccactgtcga tgcgtacgcc ttggaagttg attttgtcac ctaattcttt
    30421 cgccacgcga atcgcacttg gcacacctga tttcaacgta tcataagtgt cgactaagaa
    30481 cacgcagtct ttatgggttt tagcgtaggc cataaatgct tcataatcat ttccataaga
    30541 ttggactaac gaatgagcat gggtcccgct agctggtatc ccaaatatct tcccagcacg
    30601 tacattgctt gttgcatctg ctccgccgat atatgccgct ctagttcccc agactgctgc
    30661 atccagttct tgtgcccgtc tagttccaaa ttccaatagt ggatcttctc cgatgacaga
    30721 tttgatacga gctgcttttg tcgcgatcaa cgtttggaaa ttgaccatat tcaacagtgc
    30781 tgtttctact aattggcagt gcgctaaagg cccttccact tggattaatg gttcatttgc
    30841 aaaaactagt tctccttcac gagcagaacg aactgttgct ttaaattcaa aattttgtaa
    30901 atactccaaa aaaccttcag gatagacttc taatccacgc aagtaagcaa tatcggaatc
    30961 attgaacgtc agattctcta aataattgac taaccgttcc aatcctgcaa aaaccgcgta
    31021 tccgtggtta aaaggcattt ctcgaaagta acattcaaaa acagcatgta aatcagctcg
    31081 acctaattcc cagtatgtct gcatcatatt gatttgatat agatccgtat gcagcgtcaa
    31141 actgtcgtct gggtaagtat tattcatctt gtattactcc tcttggcaag ttttcatttc
    31201 ctacccatta taacaaaaaa aattaatagg aaaagaaatc ttccattttt tctgaaaaag
    31261 cacatgtttt acggatattt cttgctaaaa atgaactcca tctgctaaaa ctatcctttc
    31321 ttattggtat ttaacctaaa cgagaaagaa tacttatttt attcaatgta tccgagacac
    31381 gaagaaatta gcgttttcta tttttcttac ttgataaaat aagtagattt tcctactaca
    31441 atcgtagccg ttaagatacc gatgattgaa caaatataac caaatgtctc tacaacataa
    31501 tcaatggcaa aagtttttga agcaataata cgtctttcct tttttgcttc ttatccccaa
    31561 agaaacggat ataacttatt atgtattgaa tttttttgga aaggcgaatt atgacaagat
    31621 ataccttgcg ttgaaaaaac tcgcggaaaa aatatcacac gtttttaaaa agatacaaag
    31681 taagaaagca gctgtcaata gaatggaaac aaaaatggcg agacatcaat cagtctcgcc
    31741 ttgtttttta ttgtatacat tagatatgga gcaggttacc ataaagatga ttattagtcg
    31801 ttattaaata gaatccttcg tatttttttg ttctatcact acaatatctt tatttggacg
    31861 tttgaattgt attccggcac gttctagctc ctgtttcact cctacatgga ctttgacatc
    31921 ttctcgtgtc atttttaaaa cgtgatgaat cgcatagtcg atttcttgcc ttgtgatttt
    31981 tttcttcgta ttgatcatca cgacttgctt tttatcatat gtgtctacca atagcagttg
    32041 tgttcgatct aacgaaaata atttgtaata attaatagcc gtattcccaa aaaagaattc
    32101 cactacttta ggataaaatg tcttaatatt taaattacta ttcacaggtg tttcgattag
    32161 cttcatctca ttcctctttt ctatatagtc gatttagatc caatcttaag ttatgttacc
    32221 atctttccta gcattaagga atcggttaca attgaacctt taaagacaaa aggatttacc
    32281 ttttatcact taatagtata acataatttc gtgagaaaaa aatacaattt tttcttgacc
    32341 atctcgttac gtaaaggatt atgcttacat ttgtcaggag gaaaaataat ggagtacaca
    32401 ataaagaaaa tgtcagagat atcaggagtc agtccgagaa ccttgcgctt ttatgatgag
    32461 attggactgc taaaaccagc taggatcaat tcttcaggtt atcggattta tggcaaaaaa
    32521 gaagtcgatc gtctgcaaca catcttattt tatcgaacaa tggcattcaa gttggatgat
    32581 atccaagagg tcttagacaa tccatctttt gaccaccaga aagctttaat caagcatcag
    32641 caaatgttgc tggaaaaacg ggcacaaatc gataccctct tgacaactgt ccaacagaca
    32701 cttgatatgt acgaaggagg aagaaaaatg agtgacaaag aaaaatttga agggtttaaa
    32761 caacaaaagt tgaaagaaaa tgaagaatcc tatggacaag agattcgaca aaaatacgga
    32821 aaaaaaaagg ttacagcatc caatgaaaaa tggatgaata tggataaaga aacgtatgaa
    32881 gaaatgcaaa ctgttgaaaa gcagatgtta tttgatctca ctctttactt aaaagaacca
    32941 gaagatgaaa gcttagcaga ccgtatcttc caagctcata agaagtggtt ctcttacagc
    33001 tggcctgaat atcagccaaa agcgcataaa ggactaggaa tgatgtacga agccgatgaa
    33061 cggttcactg catattatga cgagcgaagt ggtcatggtg cagcaaaagc tttaaatgaa
    33121 attatccaaa aaaaggcgta atcttttaca tgatccaaca aaaaagtaca cgtaaaatga
    33181 cctaataaca aaacagcaga cacccaagtt agatttttat gctaactttt ggtgtctgct
    33241 ccattctttc acaagttttt tcatcctact ttaaatatat tcatcgttga ataaacgtat
    33301 aaggtatttt cactttatcc tttttttctg taagaaacaa ttgaaatgcc atttctccgc
    33361 aagcttccag atggtggtcg atggttggga aaccaagaag ctcgctgatc agcaaattat
    33421 cgcgtccaat caccactggt gtcttatctt gcagatagct ttgcaagatg cctgctgcaa
    33481 ccatatccga atttgtaaag acaccatcaa ctccaagctc tttaaaaaag aagcctgctt
    33541 gttttccttt ctctgcatct atacaatccc aaaaaacaag tgattcatca aaagatggaa
    33601 aaagttgatg acatagctgc aaagtgattt ttgagttata acttagcctg ccacttcgcc
    33661 ccaacgtgat gcccaattgc tttatacctt gctgcttcaa ataagtaaga ccttctgtaa
    33721 ttgattgttc tcgatcaata aagacacagc ttgcctgttt tcccttgatt tcttcacaaa
    33781 aaactagagg tccatatttt tgatatgcca ataaatcatc tagtgtattg gcacgagacg
    33841 taatgatcaa tccatcgaaa gctttagctg caaattcttc aagatacctt cgctcttttt
    33901 ctttatgata gcccgtcggt aaaagtgtca ctttgtaatc ataatcaaac gctgcttcaa
    33961 tgatcccact gatcaactga tcaaaatacg gatgattggt ataaggcaga atcactccaa
    34021 tgcttttcgt ttttccataa cttaactgtc tggcatttgc attagggata taatcgactt
    34081 ctttcatgac cgcaagtatt tctttccttt tttcctcatc tacatatgga tgtccattga
    34141 ttacacgtga aatagtagaa actgaataac ctgtgagctt tgcgatatct cgaatgtttg
    34201 ccactgctgc ttcgccacct atacaaaaag attttcttgt aaatagtcta ccacagctgg
    34261 accgcattca aaaaactgat acatttttcc ttcatgcgaa aaactgatcc gctgcccgcc
    34321 ccaatatata tcttttgtca aattttcgat ttcattcatt ggtatttctt ttactatatt
    34381 cctattcaac ccttgaaaac tgtacaacgt taatacggat cccttgaact cgacaaacgc
    34441 ataaaaataa ttgttcgttg tgccatctgt tatctctaca taagtattca ttgcaagccc
    34501 tccttttgat actttgagta tagtgtatga aacgcgtctc atagcaagga gtttgttttg
    34561 ccaaagaaaa gttttattcc tctttcatta ttaccaaagt ctcttatttt aaattgaata
    34621 cattataatg atactgtaaa tatatcttta ttattagtga at
//
LOCUS       DACGEU010000021        34093 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.021, whole genome shotgun sequence.
ACCESSION   DACGEU010000021 DACGEU010000000
VERSION     DACGEU010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34093)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34093)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34093
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.021"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(29..1261)
                     /locus_tag="IXR40_000942"
     CDS             complement(29..1261)
                     /locus_tag="IXR40_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HAQ4360810.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            1516..2085
                     /locus_tag="IXR40_000943"
     CDS             1516..2085
                     /locus_tag="IXR40_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAQ4360811.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEGQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(2263..2703)
                     /locus_tag="IXR40_000944"
     CDS             complement(2263..2703)
                     /locus_tag="IXR40_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HAQ4360812.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            2861..3625
                     /gene="map"
                     /locus_tag="IXR40_000945"
     CDS             2861..3625
                     /gene="map"
                     /locus_tag="IXR40_000945"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HAQ4360813.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            3657..4580
                     /locus_tag="IXR40_000946"
     CDS             3657..4580
                     /locus_tag="IXR40_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HAQ4360814.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            complement(4805..5044)
                     /locus_tag="IXR40_000947"
     CDS             complement(4805..5044)
                     /locus_tag="IXR40_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008788617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4360815.1"
                     /translation="MSKDYGYPSFELICKASSGDEMAVKEILKFYDGYISKLCLRPFY
                     HSESGKIIMQVDEELKGEIHTDMMKAILKFEIGVK"
     gene            complement(5049..5468)
                     /locus_tag="IXR40_000948"
     CDS             complement(5049..5468)
                     /locus_tag="IXR40_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009269612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAQ4360816.1"
                     /translation="MRTSSFEHIVRLQFNSLMLIVIKNKVKSRNRQLARHSKREVLFC
                     EIAETKQVERGTIDTCFYDCVSFKVLHFTIYVSDETLGTVLHRLSEKQRSAILLRYFQ
                     GMNDREISELYHVSRSAICSRRTRGLRKLKMLLSERK"
     gene            complement(5695..6933)
                     /locus_tag="IXR40_000949"
     CDS             complement(5695..6933)
                     /locus_tag="IXR40_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004081244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAQ4360817.1"
                     /translation="MQAEKKLFNRDFILVVIGQIISLFGNAILRFALPYYLLKETGSS
                     ALFGIATACSFLPMVILSLVGGIIADRTNKRNIMVILDFVTAIIILVFYLSLGKIPII
                     PLFIVALMLLYGISGAYQPAVQASIPLLVSSDKLTVGNAIINQVNTLANFIGPAISGV
                     VFQFYGINPILIVSIICFTFSAIMEIFIHIPHQKRPREVGVIAVAKNDLKDSYTFLKK
                     EKPIFISVIFLVCIFNLVLSAVLIVGLPILISEVLKMPDTLYGFSQSALSLGGLCGGI
                     LTALVASKLKLKNLYTLLLICSVSVLLMGISLFLELPAIVSYWVVTVMCFVAMGVSTM
                     FVVQIYTLVQTQTPPQLVGKIMATLVAVAMCGQPIGQMVYGILFDVFIQETWVVMFVA
                     SIASIMISIYSKRIFQKLEI"
     gene            complement(7040..7675)
                     /locus_tag="IXR40_000950"
     CDS             complement(7040..7675)
                     /locus_tag="IXR40_000950"
                     /inference="COORDINATES: protein motif:HMM:NF012655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAQ4360818.1"
                     /translation="MARNKYPEETVKLILDVSTKMFCEKGYDNTSLQDIINETKLSKG
                     AIYHHFDSKEDILKAIFQRIGNENAVIFAKIRDNDSLNGLEKLREIFKTAVFNSNQSV
                     LLTVSPQLLNNPRFLAMQIEQMYEIVVPEFVEPVLEQGIKDKSLEIENSHEIAEVIMV
                     LSNVWLNPLVEMTDKEGMEKRCNTFNALLNGIGIDTLLDEETISAFIQFCK"
     gene            complement(7789..7881)
                     /locus_tag="IXR40_000951"
                     /pseudo
     CDS             complement(7789..7881)
                     /locus_tag="IXR40_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323349.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            complement(8017..8652)
                     /locus_tag="IXR40_000952"
     CDS             complement(8017..8652)
                     /locus_tag="IXR40_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4360819.1"
                     /translation="MEGYAMKISHLGNNIQTIRKFRGMKQQELADKIGINMQSLSKIE
                     RGLNYPAYETLEKIMEVLDVTPNELLSGEWKYVNQSEKEVCQFLRAEERLNAELKHGH
                     YDNFFDSEEEWLEYELEKLREYITDYINGKSIEASDLYPIKEFIQHLKFQKLLDRYDD
                     LYSMDMFGESIEGHKYKTPYQVVKMINPNSKEDMELLREVLRNNNFDDEDE"
     gene            9164..10306
                     /locus_tag="IXR40_000953"
     CDS             9164..10306
                     /locus_tag="IXR40_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAQ4360820.1"
                     /translation="MNNLEFALEMKNKRLASGLSQGELASLTHVSRYSINRFENGKAN
                     ASKETQNIILRCLNYYICDKPFYLLVDYLSVRFPTTDALEVIRKVLGMKADYFIHYDY
                     GYYGYKEHYAYGEIKVMASDDEHMGVFLELKGAGSRNMEYVLQAQNRDWYSFLNRCLD
                     CGGVIRRFDLAINDMCGLLDIPVLSEKYRNGGAECRCKNYENVQGGKLSGKNRNLAST
                     LYIGSKASTKYFCLYEKQKEQATKKKHTDIINRFEIRLRDKKAVQAVEELLLTYNPHG
                     LVFYLITDFVEFPDYPLWEIFISHDSLPFEMNPVPVNMERTLQWLERQVMPSIVMIEE
                     IDRLTGSNYMKMIDECTHLSEKQEMLVEQMCTDISDVIESEGVFYE"
     gene            10299..10505
                     /locus_tag="IXR40_000954"
     CDS             10299..10505
                     /locus_tag="IXR40_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HAQ4360821.1"
                     /translation="MSNTQDIPVWEKYTLTIEEASKYFRIGENKLRRLAEENKDAGWL
                     IMNGNRIQIKRRQFEKVIDKLDAI"
     gene            10584..11777
                     /locus_tag="IXR40_000955"
     CDS             10584..11777
                     /locus_tag="IXR40_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAQ4360822.1"
                     /translation="MKEKRRDNKGRILHTGESQRTDGKYLYKYVDALGNTKYVYAWRL
                     TPTDPTPKGKREKPSLRELEQQIRRDIEDGIDSTGKKMTLCQLYAKQNAQRTNVKKST
                     QKQREQLMRLLKEDKLGARSIDTIKPSDAKEWALRMKDKGFSYNTINNHKRSLKASFY
                     IAIQDDYVRKNPFDFKLSEVIENDTKEKVALTEEQEQALLSFIKTDNVYHKHYDDVLI
                     LLKTGLRISELCGLTVADIDFKNEVVIIDHQLLKSKEQGYYIETPKTKSGIRQVPLSK
                     ETIQAFQRVINSRPKIKSIEVDGHSGFVFINPKGNPKVAIDYNALFIRMVKKYNKHHK
                     DNPLPHITPHTLRHTFCTRLASKNMNPKDLQYIMGHSNISITMNWYAHASIDTAKSEV
                     QRLIA"
     gene            complement(11784..11942)
                     /locus_tag="IXR40_000956"
                     /pseudo
     CDS             complement(11784..11942)
                     /locus_tag="IXR40_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008788611.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin-binding domain-containing protein"
     gene            11982..13121
                     /locus_tag="IXR40_000957"
     CDS             11982..13121
                     /locus_tag="IXR40_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HAQ4360823.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            13114..13914
                     /locus_tag="IXR40_000958"
     CDS             13114..13914
                     /locus_tag="IXR40_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAQ4360824.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            13914..14741
                     /locus_tag="IXR40_000959"
     CDS             13914..14741
                     /locus_tag="IXR40_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAQ4360825.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            14719..15453
                     /locus_tag="IXR40_000960"
     CDS             14719..15453
                     /locus_tag="IXR40_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAQ4360826.1"
                     /translation="MLRIGRCEFVRSVCIATFNGGRYLREQLDSILSQLSAEDEVVIS
                     DDGSVDDTWDILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWL
                     ETKVKKITDYFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYI
                     GAGMAFRSSLKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIET
                     HSKLRQKISWRVHLITALIKRKWFKR"
     gene            15553..16419
                     /gene="rfbA"
                     /locus_tag="IXR40_000961"
     CDS             15553..16419
                     /gene="rfbA"
                     /locus_tag="IXR40_000961"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HAQ4360827.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            16433..17005
                     /gene="rfbC"
                     /locus_tag="IXR40_000962"
     CDS             16433..17005
                     /gene="rfbC"
                     /locus_tag="IXR40_000962"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HAQ4360828.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            17027..18055
                     /gene="rfbB"
                     /locus_tag="IXR40_000963"
     CDS             17027..18055
                     /gene="rfbB"
                     /locus_tag="IXR40_000963"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HAQ4360829.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTNILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWKPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            18153..19004
                     /gene="rfbD"
                     /locus_tag="IXR40_000964"
     CDS             18153..19004
                     /gene="rfbD"
                     /locus_tag="IXR40_000964"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HAQ4360830.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLQYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEELGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            19038..21071
                     /locus_tag="IXR40_000965"
     CDS             19038..21071
                     /locus_tag="IXR40_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360831.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFPLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMTAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFAALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            21115..22395
                     /locus_tag="IXR40_000966"
     CDS             21115..22395
                     /locus_tag="IXR40_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HAQ4360832.1"
                     /translation="MEIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGLGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFSVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNIIGSSLMTLALLISGFASSFERWYVRIIGAVAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQILLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIAALLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYPWVPIIYILLAMAVHRYDEPEVAEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
     gene            22605..23411
                     /locus_tag="IXR40_000967"
     CDS             22605..23411
                     /locus_tag="IXR40_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4360833.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            23423..24643
                     /locus_tag="IXR40_000968"
     CDS             23423..24643
                     /locus_tag="IXR40_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4360834.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGEVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            24633..26219
                     /locus_tag="IXR40_000969"
     CDS             24633..26219
                     /locus_tag="IXR40_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAQ4360835.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLFINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAEPQNSNYVKVLEVTQQTKQDETIQQIPFNNFTGENETLSFPVSETT
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKELPEFVLTDISG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHHLLEENTRLD
                     HTLKTTTNRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSICIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVSREEVNQAEQLAKGTEAGFELRILCEQ
                     ERSFLVEAVAQNGQSWIIEM"
     gene            26258..28396
                     /locus_tag="IXR40_000970"
     CDS             26258..28396
                     /locus_tag="IXR40_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAQ4360836.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEAQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRKENGHISLATNSALEIAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDVIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPADHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVRPGRISGFYEIAYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYSNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTVMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPAYIAHDPFYNDNLTKEGIGDFSLRPD"
     gene            complement(28764..29747)
                     /locus_tag="IXR40_000971"
     CDS             complement(28764..29747)
                     /locus_tag="IXR40_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HAQ4360837.1"
                     /translation="MNKQELHDFIGFRQPNICQIVAYKDGVEVYTDEWNGYKKDDTCH
                     IMSATKSIVSLLIGIALEQGLIKSIDDKVLDYFPEYKVKRGEKTIYAITIKHLLTMKA
                     PYKCKGDPWTKVCSSEDWTKTSLDLLGGRKGITGEFNYQTVCLHILTGLLYQTSKLTT
                     VDFANKYLFDPIGIPNHVNYYAETAEEHKQFTMDKSPKTNVWFCDPLNIGTAGYGLCL
                     SASDLAKIGVLCLNKGMYKGKQIVPPMWINEMFKPRTSALEDLQNMRYGYLWWVLDSE
                     NEIYSAIGNSGNVLYIDAKNNLVISITSYFKPMIIDRVAFVEEYLKPFILK"
     gene            30125..31516
                     /locus_tag="IXR40_000972"
     CDS             30125..31516
                     /locus_tag="IXR40_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HAQ4360838.1"
                     /translation="MNKNGEWSAARRIFIILMDVIVYNAAIYSSFLLKFRGEIPLRNL
                     ETFQHSAIIISVIFIALNILLGAYVFYNRMISDIVFVTVIGQVLMTLGIMVVTFAGRW
                     FAFPRLVILLSFVLGTLFLSIYRILVYKLYLRVSRDKKVVIIGLEKDVAPAIQNFGSK
                     KNNKHKVEAVILDNYYANIKNMIKDIDIVYLASHIEETEKIKIYQLVTKNEKKLFLNT
                     TFENLTLINPNIMNFEDESIIEASGFRIQPEYELFKRLFDIIVSLVLLVIASPFMLFT
                     AILVKVTSPGPIIYKQVRITKNQKEFSIYKFRSMTATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNAENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLMLDLKILLQTIKILFDKMSPQGLEEDENVIS
                     LAEIAFPNEKIFR"
     gene            31532..32572
                     /locus_tag="IXR40_000973"
     CDS             31532..32572
                     /locus_tag="IXR40_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAQ4360839.1"
                     /translation="MNNPKFSIIVPVYNAEATIGRTIDILKELDYEEYEVVLVNDGST
                     DQTQEIIQELIENDERFELITTTNQGPGLARNEGIRQSKGEYLLFFDADDTPVKTILS
                     DYDHLLEKSPKADLVVSSFVFRTMDEGRIVSEKENLVTECHYLTHEEFIKDMYQLMNE
                     QLMYVVWNKCYRSDILKNNQILFKTYNSCEDRIFNLHYYEYCHQVIMNPKVEYIYEFE
                     GGKGITNQYRPNKFETFKEFYSLANTVTDDINKDGMAALLLKGTTSVIFSIYSTSART
                     SKEKKDEAKQILSDPVIREAKQIAKTDSSAKKITKLLYNMPAPLFLSAVKVGSFVEVK
                     MPGLMAALKRVY"
     gene            32591..33676
                     /locus_tag="IXR40_000974"
     CDS             32591..33676
                     /locus_tag="IXR40_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HAQ4360840.1"
                     /translation="MKRILHFQGRMGLGGAESFMMNLYRKIDRTNYQFDFLIYEDYAD
                     VQDYHSEIERLGGRIFVVPNPKKNIFKYLIEVNKLLKKESFSIVHNQVYFGGGINLWL
                     AKKNGIRQRIAHSHATEDGKSQNIVMNVLRKFLTKLLLQNATDYLAVSQEAGESLFQN
                     HPFEIVHNGIDLELYSKNSEAKVNKRKELDISMSTFVVGNIGRLEKQKNQSYLLEIFL
                     EILKMNSDSYLILVGEGSLRNKLKAKAVELDIEKRVKFLGERNDIPELLSVMDVFVMP
                     SLYEGLPMVGLEAQAAKLKLVLADTISKDTKLTNNVDFVSLDETPQEWAKKVIKEPYA
                     NKITQELKSYDVSYTTEQMESIYSRDH"
     gene            33709..>34093
                     /locus_tag="IXR40_000975"
     CDS             33709..>34093
                     /locus_tag="IXR40_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-1,6-N-acetylglucosaminyltransferase"
                     /protein_id="HAQ4360841.1"
                     /translation="MKICYLILAYNDIGNLKRLVNRLNENAVFIIHIDKKTDIEPFIE
                     AFKSYDNVEFLCNKNRVKIYWGGFSIVQAEINLVKRALQNEKYLKYVLLSGADYPIKD
                     NEYIYNYFKKNSSVEFIRGIDLDQIK"
BASE COUNT        11056 a         5834 c         6717 g        10486 t
ORIGIN      
        1 tattttttgc atgtgtgcga aagtatactc aagcccaatc gccatttcgg aaaatcggta
       61 ctgtagagcc atcttcacgg attccgtcga tatccatctt gtcagatcct accatgaaat
      121 ctacgtgggt ttgacttcta ttcaatccag cttctgctaa ttcttcatcg gacatttctg
      181 taccgccttt cacactgaag gcataagcag aacctagtgc taagtgattc gatgcgtttt
      241 catcaaataa tgtattgaaa aagatgatgc cagattgaga aataggtgaa gggtcaggta
      301 caagtgcgac ttctcctaaa cgacgcgcac cttcatctgt atcaagcagt tttgctaaga
      361 catcttctcc ttgttcggca gaaaaatcaa caacttttcc atctttaaaa gtaaatttca
      421 tacccgagat gatggtgcca gcataactca gtggctttgt acttgaaatg taaccatcta
      481 ctcgatgact gtcaggtgct gtgaacactt cttccgtcgg catatttgcc atgaattttt
      541 ctccacgagc attatagctt ccagcgcctt cccaaagatg gtttttaggc aatccgataa
      601 tgatatctgt accgggagca gtatagtgaa gggcagaaaa ttgttctcga ttcaattctt
      661 ctgctttttt tgctaatttt tcatcatgct tcttccatgc taagacaggg tcttcttcat
      721 agacacgagt cgttttgaaa atctgatccc ataatgcctc aacttgtttt tcttctggca
      781 gttctgggaa gacttttgct gcccattgtt taccagccgc agccacgaca gtccaactga
      841 ctttatttgc ttgagttgcc ttgcgtaaat tcattagtgc tttgccattc gctgattgat
      901 aagacgctac tcgatggcta tctacaccag caaatgcatc gggatcggca gaaacaacgc
      961 tgatcctgct tgctcctttt tcaagccatt catccgcttg atcgatttta gattgtggta
     1021 cattctcaat acgatccgtt gcagcatgta aaagaaattc tctttggatc tggtcgtcag
     1081 tccattgaac gataacctca gcggctccta gtttataagc ttcttgtgtg atcaatcgag
     1141 caaggggtgc ctgttccacg ctgatctgta aaacaactgt gtgtcctttt tctgtggcta
     1201 cgccagtttc tgcaattaag cgtgcatatt tttttagaag ttcattaaaa tcagataaca
     1261 taataaaaat tcctcctcac cattttttct ggtaactatt agcatgatac catttaatta
     1321 tgattcaaac aatgaggctt taaataaaaa aaggaggtta tttttttaag gttaagtttc
     1381 atgatatatg ttactacttg ctatttcagc ttgtgaagaa aatcaaaaac taattttgca
     1441 tatcaaaaaa aacatgttac aatgaaatta atcaatggtg gaagcgttat aaaaaaatta
     1501 aggagattaa aaaatatggc aagaaaaaag acgattacta gagaacagat tttggcagct
     1561 gcttatgaag tagctgccac cgatggattt acacgattta ctgcgagaaa catcgcgaac
     1621 aaaatgaatt gttccacgca accgatttat cttgagttta aaaatatgga tgacttgaga
     1681 caagctcttt ttgagcagat ctatgatcat ttacaatatg aagtgttcac tgttgagcat
     1741 acagggaata cgattatcga tcttgctttt aattatatcc attttgcaag aagagagaag
     1801 aagttgtatc gttcactgta cttagaagaa tatggtggag gaaaagagat gcagaatttc
     1861 tcttatactt actttgtgaa tacagtgaaa cgcgatccag cttatgtgaa tctttcagaa
     1921 gggcagatcg aatctttgta taatgggaca tggatcatag ctactgggat cgcagctttg
     1981 atgtcttcaa gcatcatcca tccaactgat gaacagattg aaaagatgat ccaagacagt
     2041 atagatgcta tcttgaaatt caaagaacca atcgaaatcg attgaatata ctcaaaagtt
     2101 ccacaaatca gtaggtaaca agagatgtgt caaaataagg aaaagttcgt ttttcttaca
     2161 gcgtatgcat ttttaactcc cgaagaactc ttccatgaat gcaatgaata aaagagccat
     2221 acagattgaa taaatctgga tggctctttt attgcaagta tattaaattt ttgcgactag
     2281 ttctttagcg aaagcttcta aattttcgat atcttcttct tcagcattca gatccacttt
     2341 aacattttcg gctccttttg atgcgcctgt ttttgcaaaa gcagcatcga aatcatccac
     2401 cgatttgcag aattcatcgt aaaaagtatc accagatccg cagacaccgt aaatttttcc
     2461 caatagatcc aattcttgca agtcttcata aaagtctacg atctcatcag gcagatcgcc
     2521 atcatcgtat gtataagtag ctactacgca aatatctgcc tcctcgaatt catctgcatc
     2581 tacttgggta cattcgttga tttcgacttc gatatccaga ttttcaaatg cttctgcaac
     2641 aatatcggcg atttcttcag tgtttcctgt catgctagca tatacgattt ttgctaaagc
     2701 catgatgtgc ctcctcgttt ataattattt aacaattatg aattatacca aaacatcatt
     2761 gaaaagaaaa taaaacctag agacacctgg ggaatgtcat ttggctaaat gtatgccgct
     2821 atgttaaaat gagagggatt tgtaaaaagg agacgaaaat atgattactt taaaatcagc
     2881 acgtgaaatt gaaatgatgg cagaatctgg agctttatta gcagatgtac ataaaaatct
     2941 gcgtgatttt ataaaaccag gaatcacaag ttgggatatt gaggtatttg tcagaaacta
     3001 tatcgagagt catggcggaa ttgctgcgca aattggcttt gaagggtatg aatatgcgac
     3061 ttgtatcagt ataaatgatg aaatttgtca tggattccct cgtaaaaagc ctttgaaaaa
     3121 cggtgatttg gtaaaagtcg atatgtgtat cgatttgaaa ggcggcattt ctgattcttg
     3181 ttgggcctat gtagttggag aatctacacc tgagatcgac cgattgatgg aagtaacgaa
     3241 gaaagctttg tacatcggta ttgagcaagc acaagtaggg aatcggattg gtgacatcgg
     3301 tcatgctatc caaacttatg tagaaggcga aaatctagcg atcgttcgtg attttattgg
     3361 tcatggcgtt ggtcctacga ttcatgaaga accagcagtt cctcattacg gagaagctgg
     3421 aaaagggttg cggttgaaag aaggcatggt tatcacgatc gaacctatgg ttaataccgg
     3481 aacttggaaa atgaaaatgg atcctaacgg ctggactgcg tatacaagag acggcggact
     3541 ttcttgccaa tatgaacata cattggctat tactaaagat ggtccaagaa ttttgacatc
     3601 acaaggagaa gaaggcactt attgatctat ccagtcaata ggtacgggag aggtacatga
     3661 aagtttggaa caaaataaaa caaaatgaaa atctgatgcg ctttattgag acgactcaaa
     3721 agcgcatcac tgattcagaa atgagtacga cctctgtcgt cgttgcttat tatttactct
     3781 tgtctttatt tccattgatt attgcttttg gtaatatttt accgtttctc cacatcgatc
     3841 aagagactgt actgacctat ttacgagaag tgattcctga gaccgtttac cagtttatcg
     3901 gtcctgcaat caaagacctt ttgacacaaa gttcaggagg cttgttatcc gtttctgcat
     3961 tagcggcttt atggtctgca agtcaaagta tcaatgcttt gcaaattgcg atgaataaag
     4021 cgtatggcgt agaaaataga aaaaattttt tgatcgtccg tttcttctca ctaattgtca
     4081 ttgtcttgtt catgattgct attagtgggg taactatcgt tcttgggttg ggacagctga
     4141 ttttggatgc tattcagcca atcgtacaaa tacccgtgaa ctttatcgat cagttccaaa
     4201 ctttgaagtg gccaatcaca ttggtagctt tatttgtcat catgttcttg atttatttaa
     4261 ttgtccctaa tgctcagttg aagttgaaga cgatcattcc gggcacgatc ttcgctactg
     4321 tcggctggat gctgttatca caagtgttta gtatctatgc taggtatttt gcaacgagga
     4381 tcagcggtta tcagatcata ggaagtttta ttgtactcat gctttggctt aattttgctg
     4441 ctacgatcat cattttgggc ggaatcatca atgcagttgt tcaagaatac gtgacgggtc
     4501 atcaaatcaa aaaacgtcga gatccaagcc gaaaatggtt caataaattg aaaactaaat
     4561 tttctcataa aaaaaagtag aaacaagagt tcttattgta aatttatatc agtaatttat
     4621 ttgaaatttt atatctaatt ttcaattatc cgcataaaca ctatacattc aagcattttg
     4681 aagtatagaa aaacactcat cttaccacga atttaccacg attgaatgag ccttgatatg
     4741 accgtaaaac tactaaggga gatagcacga aactgtgtat ctcccgattt ttttatacag
     4801 ttgattactt cactccgatt tcaaatttca atattgcttt catcatgtct gtatgaattt
     4861 ctccttttag ttcttcatca acctgcataa tgattttacc actttcagag tggtaaaaag
     4921 gacgcaagca taatttagaa atataaccgt cataaaactt caaaatctct ttaactgcca
     4981 tttcatctcc gcttgacgct ttgcaaatca attcaaaaga gggatagcca taatctttac
     5041 tcatttcttt acttcctttc gctcaaaagc atttttaact tccttagtcc tctagttctt
     5101 ctactgcaaa tagcagaacg tgatacatgg tacagttctg aaatttctct gtcgttcatt
     5161 ccttgaaaat aacgtaataa aatcgcacta cgctgttttt ctgacagtct atgtaaaact
     5221 gtaccaagtg tttcatcaga tacataaatt gtaaagtgca agactttaaa tgatacacaa
     5281 tcataaaaac aggtatcaat cgttccacgt tcaacttgtt tcgtttcggc tatttcacaa
     5341 aacaatactt cacgtttaga atgtcttgca agctgtctgt ttcgactttt cactttgttc
     5401 ttaatgacaa tcagcattaa agaattgaac tgtaatctga cgatatgctc gaaagaagat
     5461 gtcctcataa tctcaccccc tttctgctaa tgctgaaata tataaacgga ataccgttta
     5521 taccctttag aaatacagaa aaatggtaag aaaaaagccc acacaaaaca tatatttgtg
     5581 cgagccttaa atactgcaat attactcttt cttttataac actatccttt tagcagattt
     5641 caaattttct tttatatatt gtttttagcc taacatacta tttaacccct tgtattatat
     5701 ctctaacttt tgaaaaattc tttttgaata tattgaaatc atgattgaag caatagaagc
     5761 tacaaacata acaacccatg tttcttgtat aaatacatcg aataaaatac cgtaaaccat
     5821 ttgtccaata ggttgaccgc acatagcaac tgctaccagc gtagccatta tctttcctac
     5881 taattgcggt ggtgtttgtg tctgaacaag agtgtaaatt tgaacaacaa acatagtaga
     5941 tacacccata gccacaaagc acatcactgt aactacccag taggaaacta ttgcaggcaa
     6001 ttctaaaaat agcgaaattc ccataagtaa aacagaaaca gaacaaataa gtaacaaggt
     6061 ataaaggttt tttagtttta actttgaagc aacaagagct gttaaaatac caccacataa
     6121 accacctaat gataatgctg attgtgaaaa accatatagt gtatctggca tttttaaaac
     6181 ttcagaaatt aagataggca gaccaacaat taaaacagca cttaaaacca aattgaaaat
     6241 gcaaaccaaa aagattacgg atataaaaat gggtttctcc tttttcaaaa aggtataact
     6301 atcttttaaa tcgtttttag caactgcaat tacacctact tcacgaggtc ttttttggtg
     6361 tggaatatgg ataaaaattt ccataatggc tgaaaaagta aaacatataa tactaacaat
     6421 taaaatggga ttgataccat aaaattgaaa aactactccg cttatagctg gtccgataaa
     6481 gtttgctaaa gtatttactt gatttattat agcattaccg acggtaagtt tatctgatga
     6541 taccaataga ggaatacttg cttgtaccgc tggttgatat gcaccagaaa taccataaag
     6601 taacatcaaa gcaacaataa acaaaggtat gataggaatt tttcccaatg acaaataaaa
     6661 tactaaaatt atgattgctg ttacaaaatc tagtatgacc ataatgtttc ttttatttgt
     6721 cctgtcagca ataataccac ctaccagcga caaaataacc ataggtaaaa aagagcaggc
     6781 tgtagcaata ccaaacaaag ctgatgaacc agtttctttt aacaaatagt acggtaatgc
     6841 aaatcgtagg atagcgtttc caaataaaga aattatctgt cctataacaa caagtataaa
     6901 atcacgatta aaaagttttt tttctgcttg cataaaatct ctccttttta tttaatcaaa
     6961 cagaccgtcg gtttatataa tggtttaaat aaactgctct tttatagagc agtctatcgt
     7021 atagggataa caaatacagt tatttacaaa actgtataaa tgcagaaatt gtttcttcgt
     7081 ctaataatgt gtctatgcct attccattta aaagggcatt gaatgtattg caacgttttt
     7141 ccataccctc tttatccgtc atttcaacta atgggttgag ccatacatta cttaatacca
     7201 tgataacttc tgcaatttca tgtgaatttt caatctccaa agacttatcc ttgatacctt
     7261 gttctaaaac gggttcaaca aattcaggta ctacaatttc atacatttgt tctatttgca
     7321 tagcaagaaa acgaggattg tttaatagtt gaggagaaac tgtcaataaa acgctttggt
     7381 tagaattgaa taccgctgtc ttaaatattt ctcttaactt ttctaaaccg tttaaactat
     7441 cgttatctct aattttagca aatattactg cattttcatt tccaattctt tgaaaaattg
     7501 cttttaaaat atcttccttt gaatcgaaat gatgataaat agcaccttta gaaagttttg
     7561 tttcattgat aatatcttgc aatgatgtgt tatcatatcc tttttcacaa aacatttttg
     7621 tagaaacatc taaaatgagt tttactgttt cttctggata tttatttcgt gccataactt
     7681 acctccaata caaaccgttg gtctgattaa agtatatctt agtattttat gcttgtcaat
     7741 ataaagactt gcaattttat aaaaatgcag aatgcaagcc tttttcattt attctacaat
     7801 cttccagttg ctttccttat gcggtgtcaa ttcatactgt gatacctgcg ttgcctttgc
     7861 ctgatttacc acaaatcaga ttttatccct ttcttcctct tgattgccca caacagaaaa
     7921 gaaaaagccc tgtcaagagc tttgccacca ttggtggtgc tttgcactct tgatcgggct
     7981 ttttgtttgc tgtatcttct cgcaagagga aaaaagttac tcgtcctcat catcaaaatt
     8041 gttattcctt aatacttctc gtaacagttc catatcttct tttgagttcg ggtttatcat
     8101 tttcacgact tgataaggtg tcttatactt atgtccctct atgctttccc caaacatatc
     8161 catactgtat aaatcatcat agcggtctaa taatttttga aacttcaaat gctggataaa
     8221 ttctttgatt gggtaaaggt cggacgcttc aatgcttttc ccgttgatat agtctgtaat
     8281 atattcccgt aacttttcta actcatattc cagccattct tcctcgctgt caaagaagtt
     8341 atcatagtgt ccatgtttca gttctgcatt tagacgttct tcggctctta aaaactgaca
     8401 gacttccttt tcagattgat tgacatactt ccattctccc gacaacaatt cattgggcgt
     8461 aacgtccagc acttccatta tcttttccag cgtttcatag gcaggatagt tcaaccctct
     8521 ttcaatcttg gaaaggctct gcatattgat accgattttg tccgcaagtt cctgttgttt
     8581 cattccccta aattttctta tggtctgtat attatttcct aaatggctta ttttcattgc
     8641 ataaccctcc atatctcgtt atatcttcgc tattataagt ctatcatgct taatatgatt
     8701 tgtaaaggca aaaaaagata ttgacaaata agcatataag aattactatg ttcttgtaat
     8761 cgaataagca caatagaatg aaatataaaa acattcaaaa agaaatacct atctgattaa
     8821 atccgtagat atgaatatcg gttgaaatgg aacttgttag aaaaggcaaa acagaacttg
     8881 ctgacaaagt atttctgaca cggtggcgga agcctctcag gcttaccgcc atgacacctt
     8941 gtgtcaaggg gaagaaatgc tttgtcggct ggcgagcctg cgagccttgt ctgtgccccc
     9001 gttatctaac aggggggcac tatttcacaa aagacaagtc aaaaaccata cacccccaaa
     9061 cctgtgagta gtaatgagag gttttaagaa gatagtacat atcacacttt ttgaaaggtg
     9121 gtttacaggt atttcaaggc tattgtggga ttggaggaat acaatgaaca atttagaatt
     9181 tgcacttgaa atgaagaaca aacgtcttgc cagcggtctt tcacaaggag aacttgcaag
     9241 tcttacccat gtatcaagat atagtatcaa ccgctttgag aacggaaaag ctaacgccag
     9301 caaggaaaca cagaacatta tcctgcgttg tctgaattac tatatctgcg ataagccttt
     9361 ttatctgctc gttgattatc tgtctgtccg ttttccaacg actgacgcat tggaagttat
     9421 ccgaaaggtg cttggcatga aagcagatta ttttatccat tatgactatg ggtattatgg
     9481 ctataaggag cattatgctt acggggaaat caaggtcatg gcttctgatg atgaacacat
     9541 gggcgtattt ttagaattaa aaggggcagg ctcacgcaac atggaatatg tcttacaggc
     9601 acagaacagg gactggtatt cattcttaaa ccgctgtctt gactgtggcg gtgttatccg
     9661 acgttttgac ttggcaatca atgatatgtg cggtctgctg gatattcctg tgctatctga
     9721 aaaatacaga aatggtggtg cggaatgtcg ctgtaaaaac tatgaaaatg tacaaggtgg
     9781 aaaattaagc ggaaaaaacc gtaatttagc aagtaccctt tatatcggct caaaggcaag
     9841 cacaaaatat ttctgcctgt atgaaaaaca aaaggaacag gcaacgaaaa agaaacatac
     9901 cgatattatc aaccgttttg aaattcgtct gcgtgacaaa aaggcggtac aggcagttga
     9961 agaactgtta ttgacgtata accctcatgg gctggtgttt tatctcatta ccgattttgt
    10021 ggaatttcct gactatccat tgtgggagat attcatttcc catgacagtt taccttttga
    10081 aatgaaccct gtacctgtca atatggaacg cactctgcaa tggctggaaa gacaggtcat
    10141 gccgtcaatc gtgatgatag aggaaatcga caggctgaca ggttcaaact acatgaaaat
    10201 gattgatgaa tgtacccacc tttctgaaaa acaggaaatg cttgtggaac agatgtgtac
    10261 ggacatatca gacgtaatcg aaagtgaggg ggtgttttat gagtaataca caggatattc
    10321 ccgtatggga aaaatacacc cttaccattg aagaagcgtc aaagtatttc cgcattggag
    10381 aaaacaagtt aagacgattg gcagaggaaa acaaggacgc tggctggctc attatgaatg
    10441 gcaaccgcat acagattaaa cgccgacagt ttgaaaaggt tattgataaa ttggacgcaa
    10501 tctaatgcaa atgagccttg tatgtgttat gatgaacaca agtcatatca aggctctttc
    10561 caacaaggaa aggagcagac accatgaaag aaaaaagacg ggataacaaa ggtcgtatcc
    10621 tgcatactgg agagagccaa cgaacagacg gaaaatactt atataaatat gtagacgcat
    10681 tgggaaacac aaaatatgtg tatgcttgga gattgacacc cacagacccg acaccaaagg
    10741 gaaaacggga aaaaccctca cttcgagaac tggaacagca gataagacgg gatattgagg
    10801 acggtatcga cagcacaggc aagaaaatga cgctttgcca actctatgcc aaacagaacg
    10861 cacagaggac aaatgtgaag aaaagcacac agaaacaacg ggaacaactc atgcggttat
    10921 taaaagagga caagttaggt gctaggagca ttgatacgat aaaaccctct gacgctaaag
    10981 aatgggcgtt acgcatgaaa gacaaaggct tttcctacaa taccattaac aaccataaac
    11041 gctcgttaaa agcgtcattc tacatagcca tacaagatga ttatgtgagg aaaaaccctt
    11101 ttgatttcaa gctaagtgaa gtcatagaaa atgataccaa agagaaagtc gcattgacag
    11161 aggaacagga gcaagcctta ttgtcattta ttaagacgga caacgtgtat cacaagcatt
    11221 atgatgatgt gctgatactg ttaaagacag gacttcgtat ctcggaactg tgcggactga
    11281 cagtagccga cattgatttc aagaatgaag ttgtgattat cgaccaccag ttactaaaga
    11341 gtaaggaaca gggctattat attgaaacgc ctaagacgaa aagcgggata aggcaagtgc
    11401 cattaagcaa agaaacgata caggcatttc aacgggttat caacagccga ccaaagataa
    11461 agtcgataga ggtagacgga cacagcggtt ttgtgtttat caatccgaaa ggtaatccaa
    11521 aagttgccat tgattataac gccttattta tccgtatggt aaagaaatac aacaagcacc
    11581 acaaggacaa tcccttgcca catattacac cgcatacgct acgccataca ttctgcacaa
    11641 ggctggcaag caagaacatg aacccgaaag atttacagta tatcatgggg cattcaaaca
    11701 tcagtatcac aatgaactgg tacgctcatg cgtccataga taccgcaaaa tcagaggttc
    11761 agcgtctaat cgcatagaag tatttaccac gattttaacc acgattgaca gggaaaatat
    11821 aagaagatag acctagatat gcgaggttta ccacaaaagc aaaatgcccg tagagccgat
    11881 aaaataaggc tttgcggaca tttgagaaga tataaaaaga tagtcaaaaa gacatatata
    11941 atttataata attatgactc ttaattaaag taggtgccca tatgcttgtt tcttttagta
    12001 tggttataag attttttctg acaattttat tatcactgat attaacacct gtattcaaaa
    12061 tcatttcagt acaaacaggt atggtcgaca aaccaaatga aagaagaata aataaagttc
    12121 caatgccttc agcgggcgga ctgcctatct ttatttcatt tgttatatcg actttattct
    12181 tattccgtaa aattatccct caatcgtata ttgtaccgat cttgattgct tctttagtaa
    12241 tcatagtcac aggagtgctc gatgataaat atgagctgac acctaaacaa aaaagtatag
    12301 ggatcttgat tgcttctctt attatttatt ttgtagcaga tatacgtatt gattccttca
    12361 cgcttccttt tattggatat atccaactag gctggcttag ttttcccgta acgatttttt
    12421 ggatcttcgg tatcacgaat gcggtcaatc tgattgacgg tttggatggg ctggcggcag
    12481 ggatttcatt gatcggttta attacgatag gaatcattgg atattttttc ctccatgctt
    12541 ctacagtgta tattccagtt gttattttct gtcttgtagc aagtattatc ggtttttttc
    12601 cttacaattt ttatccggca aagatttatt taggcgatac aggagctcta ttcctagggt
    12661 ttatgatggc cgtcctttca ctacaagggc tgaagaacgt gacttttgtt tcatcgattt
    12721 ctttgctgat cgtcatggga gtgccggtaa cagacacgtt ttttgctatc attaggagaa
    12781 aagcaaaccg tgtttctttt tctacagcag ataaaaaaca tcttcatcac cgactaatca
    12841 gtttaggctt tactcataaa ggtgctgtcc tgacgattta tgcgatggct ttgatgtttt
    12901 ctttcacagc tatggtcatg aattatactg gaagaatcgg aacgatcata ttgattattg
    12961 ccatgttgtt tgctgcaatt ttattatttg aattgattgg tctgatcaat gagaaacatc
    13021 agtttatttt aaaaacattg cgatttttag ggaataaaga gtaccgtacg caagtaaaac
    13081 agaaatattt gaagaaatgg aaccgtcata tagatgaata acaaattaaa ccagccgatc
    13141 cttattagta ttgtgacggc aaacagtgat aaaatttttc ggacactaga taattttatt
    13201 tcaactgtaa aagatgaaac agcagtaaaa atccgaattt ttgacaacaa ttcacttccc
    13261 gagtacaaaa aaagactaac agagtatagg aaatatccct acatcgatat ctattttcat
    13321 gatgaaaatt ccggatttgg ttatggacat aatcacaatc tgatagctag cgattctcgc
    13381 tatggcatta tttgtaaccc agatatttta gtggatgaag agacagttac agcattggtc
    13441 ttgttattga aagaacatcc ggaatgtgcg atgttagcac ctaagattct taatgaagat
    13501 ggaacaactc agcacctcat ccgtgagcag ctggctgttt ttgattacgt tttgcgcttt
    13561 gtgcctttca aatgggtcaa aaaaaagttt gacaaacgac tggctgtgtt tgaatgccga
    13621 ggattgccta ctgatgctaa tagttatgta cggatgatct caggtagttt tatggtagct
    13681 gatattgata aatttaaaga gataaagggg tttgatgagc gtttcttcat gtactttgaa
    13741 gacaacgact tgtgtttgag ttttgaaaaa gcaggttaca agttattgta cacacccttt
    13801 tatgcagtta tccattttta cgggaagggt gcgcatcgaa atgcaaaact gtttcgcgtg
    13861 tttttgactt ctatgatgaa atttttcaat aagtgggggt ggcgtttttt ctgatgaaac
    13921 cagaaatatt agtagtcgtt gtgctttatc agcaactatt cagtcaatct ccagcttatg
    13981 gaccattaag caaagcactt agcgaaaagc aaattcagct tattatttac gataatagtc
    14041 ctcaaaggca gcaaaatgag ctgtttgaaa aagaaaatat cgtttatcat catgatccgc
    14101 aaaatcctgg tttagcggtg gcttataatt ttgcgttgtc tcaagcagat gaaggaacac
    14161 gttgtctcgt cactctggat caggatacga ggctagtcga cgattatttt gaactattgc
    14221 gtaaagtaac ctttacagat gaatgtgttg ctgcagttcc gatgattttt tctgggagcc
    14281 gacaagtttc tcccctatat tcagatcgtt atatcaatcg tacagctcaa gcagtagaag
    14341 ttgaaggccc aacagctgaa cgaatcatgg caatcaattc aggtgttgcc tggtctgtca
    14401 aatttctaaa aaagattggc gggtttaatc ctgctttttc tttagatttt ttggatcatt
    14461 ggctgttttg gaaagtggat cagttggaaa aaactgtgga gatccttcct gtacgaatgg
    14521 aacatgatct ttcggtttta gactatgaaa aagtttcaag taatcgatac cgttctattt
    14581 tacaagcaga aaatcgattt tatcatgaat atgatcaaag gcatttatcc agtcaccgac
    14641 gacaattatt gttaagaaca gctaaacagt tcttgaccgt caaaaaccgg catatctggc
    14701 ggatgacttt gcgctcatat gttaagaatt ggaaggtgtg aattcgtgcg ttcggtttgt
    14761 atagctacct ttaatggagg cagatattta agagagcagt tagatagtat tttatctcag
    14821 ctttcagcag aagatgaagt agtcatttct gatgatgggt cagtagatga tacatgggat
    14881 atattaactg aatacgcaga aaaagataag cgaatccagc ttttttcggg gcctcgtcaa
    14941 ggattgatcg ctaattttgg ttatgcgatc cagcagacga aaggagatct aatctttttg
    15001 gcagaccaag atgatgtttg gttggagaca aaagtgaaaa agatcactga ctattttgag
    15061 cagaatccgg atcagctagt agtagtttct gatttaatca ttgtggacag cgagctgcaa
    15121 gagatccatg attcgtattt ttcgtttcga aattccaaag aaggatggct taataatgtg
    15181 ataagaagtc actatattgg tgctggtatg gctttccggt cttctttaaa acccgatatt
    15241 ttgccgatcc cgtcagaagt gccgatgcat gatatgtgga ttggtttgct gggaggaaag
    15301 aagactgggt tcctaagaga accgttaact ctgtaccgaa gacatgattt aaacgcgagt
    15361 gagattgaaa cacattctaa attacggcaa aaaatttctt ggcgtgttca tctgattacg
    15421 gcgttgatca aacgaaaatg gtttaaacgt tgataaaaga tgtttaaatc cttaatattt
    15481 ccatgacaaa tataacaatt gatgagataa taacaaagtg aaatttgaaa tcaaaaagga
    15541 gagcagatat ccatgaaggg aatcattctt gctgggggca gcggaacacg tctgtaccct
    15601 ttaacaaagg caacatcgaa acaattgatg ccgatttatg acaaaccaat gatttattat
    15661 ccaatgtcta ctctgatgtt ggcgggaatc aaagaaattc tgattatttc aacgccacaa
    15721 gatacaccac gtttcaagga attatttgga aacggaaatg atttaggact gcagatcgaa
    15781 tatgcagtac aagaaagtcc agatggattg gcacaagcgt ttatcattgg agaagaattt
    15841 attggagatg atagtgtctg cttggtatta ggggacaata tttactatgg tggcggtctg
    15901 tctaaaatgt tgcaacgagc agcttcaaaa gatacaggcg cgacagtatt tggctatcat
    15961 gtcaatgatc cagaacgctt tggtgtagta gaatttgatg agaatatgca agctttgtcg
    16021 attgaagaaa agcctgctca gccaaaatca aattacgctg taactggcct ttatttttat
    16081 gacaatgagg taatttctat cgctaaaggt atcaaacctt cagaacgtgg agaactagag
    16141 attacggatg tcaataaagc atatttggat aaaggaaaac tatccgtaga acttatggga
    16201 cgcggatttg cttggcttga tacaggaaca catgaatcat tgcttgaagc atctaccttt
    16261 atcgaaacaa ttgaaaaacg tcagaactta aaagtggctt gtttggaaga aattgcttac
    16321 cgtatgggct acatcgataa ggaacaattg ctggcccttg cacagccatt gaaaaaaaat
    16381 caatacggtc aatatttatt gaatttggcc gctgaataag gagtccttac agatgaaagt
    16441 aacagataca aaattaacag atgtcaaaat cgtagaaatg gacgtctttg gcgatcatcg
    16501 cggtttcttc acagaaagtt attcaaaagc aaaatttgca gaacatggat tgaaatatga
    16561 ctttgttcaa gacaaccatt cactatcagc tgaagctggt gtccttcggg ggcttcattt
    16621 ccaaaaagga gaagctgcac agacaaaatt gattcgggta gtcactggag cagttttaga
    16681 tgtagtagtg gatatccgca aaggtagccc gacttatggt caatgggacg gatttatctt
    16741 atctgaacat aatcatcgac agttgcttgt acctaaagga tatgcccatg gattcgttac
    16801 tttgacacca aatgtgaact tcctttataa gtgtgataat tactataatg cagaagcaga
    16861 tgggggcatc gcatttgatg atccagattt agcgattgat tggccaattg atccatcaag
    16921 agcgattatg tcggaaaaag atcaccgtca tccgacatta aaagaatttg aagcagaaaa
    16981 tccatttgtt tacggagaaa tctaagaatt aaggagaaat tttcttatga aaaacatcat
    17041 tgttaccgga ggtgccggat tcatcggctc taatttcgtt cattacgtgg taaacaatca
    17101 tccagaagtg catgtcactg ttttggataa actgacttat gcaggaaaca aagagaactt
    17161 ggctggactt cctagcgatc gcgtagaatt ggtcgtagga gatgttgcag atgcagaatt
    17221 agtggaccgt ctagtaaaag aagcggacgc agttgttcat tacgcggcag aatcccataa
    17281 cgataattca ttaaaagatc ctttcccatt tgtacaaacg aatatcattg gtacgtatac
    17341 acttttagaa gcttgccgca agtatgatgt acgctatcat cacgtatcta ctgacgaggt
    17401 ttacggcgat cttccattac gtgaagacct gccaggacat ggggaaggcg aaggagaaaa
    17461 attcactgcg gaaacaccat ataatccttc aagtccatat tcttctacaa aagctggttc
    17521 agatctgtta gtaaaagcat gggtgcgttc ttttggctta cgtgcaacca tttcaaactg
    17581 ttcaaacaac tatggtcctt atcagcatat tgaaaaattt attcctcgcc aagtaacgaa
    17641 tatcttaagc ggtattcgtc caaaattata tggcgaagga aagaatgttc gtgactggat
    17701 ccatacgaat gatcattctt cagcagtgtg gctgattttg acgaaaggca gaattggcga
    17761 aacctatctg atcggtgcag acggtgaaga agataataag accgtgatgg aattgatctt
    17821 agaaatgatg ggtcaaccaa aagatgcgta cgaccatgta aacgaccgtg caggacacga
    17881 cttgcgttat gcaatcgatt cgacaaaatt acgggaagag ttaggatgga agcctgagtt
    17941 tacgaacttc cgtgatgggt tggctgacac gatcaaatgg tacgaagaac atgaagactg
    18001 gtggaaaaaa gaaaaagagg ccgttgaagc agcatatgcc aaaaatggac aataatacag
    18061 agaaaatgtc actgtattaa tggaaaaaca catgtgaggc aggcgctcgc ctgtctcttt
    18121 tttaaaataa aaatcaagga gcggataatc atatgttttt attaactgga ggaaatgggc
    18181 aactaggtac agaattgcgc catttattag atgaaaaaaa tctgcaatat gtttcaacag
    18241 atgcaaaaga cttggatatc acagatgccg agaaaacaat ggcttacatc acagaattaa
    18301 aacctgatgt tattttccat tgtgcagctt acacagcagt agataaagca gaagaagaag
    18361 caaaagaatt agatgagaag atcaatgttg atggtacaag aaatgtagca cttgcagcaa
    18421 aagctgtgaa tgctcaattc gtctatatca gtacagacta tgttttcgat ggaaaaaaca
    18481 aaaatgtaga atacgaagta gacgaccaaa cgaatccact aaatgaatat ggtcgtacga
    18541 aattattagg cgaaaaagca gtagaagaga ttttagaaga ctattatatc atacgaactt
    18601 cttgggtttt cgggatctat ggacacaatt tcgtcttcac gatgcaacgc ctagcggaaa
    18661 cccgcgacaa actgactgta gtaaatgacc agtttgggcg accaacttgg acacgtactt
    18721 tggcagaatt tatggtatat gtcatcgaag aaaaagcacc atttggtatt tatcatttgt
    18781 cgaacgaaaa tagctgttct tggtatgaat tcgcaaaaga aatattgaaa gatacagatg
    18841 tagaagttgc acctgttacg tcagaagaat ttccgcaaaa agcaacacgt ccgcagtatt
    18901 cagtcatgag cctgaaaaag acagaagagt taggatttgt cataccaact tggcaagaag
    18961 cacttgcgca aatgctggaa gctgccaaaa aaatgaataa gtaatttcct tttatcaaat
    19021 agaatttgga gcatgatatg gaaaaacaaa caagaagtgc acgacgaaaa gaaaagccaa
    19081 aagcgaacca ggcagattcg aatttggtgc ttgacctgtt tctaaaactc cgctatctta
    19141 ttggcgtttt agtcatcgtg gtcatcgtta cttttaattt aaacggaagt tcacttggtg
    19201 tttgggataa atatgtgtcg caaagagacg atgggaaaaa aactgatgtg atttttggac
    19261 agaatcggga agtgcggtca gacgaatggc tggtgcagac acctttttac ctctcacaag
    19321 ctgaagagga ctttccgttg gtgaacgagg attattcatt aaacggacaa aacatgatca
    19381 ttgcgtataa ttctcctgta aaggatatta cggttatcgg aaaaccattc aactggggat
    19441 tctttttcct cggaagagat cgaggacttt ccttttattg ggcgatgaaa ttagtcgtca
    19501 tggtcttgct tggattcgaa gtactgatga tattaacgaa gagaaaaaaa gctctatcgc
    19561 taatcggtgc atttgcgctg acattttctc cagcagtcca gtggtggttc atgcaacatg
    19621 tgggcgattt gattttcttt actttgggac tgatgactgc tttttatcat tatttctaca
    19681 atcatgataa aaaatggcta cgaacgttga tgatgctttt ggtggttatt ttcggtattg
    19741 ggtttatttt agtgatttac ccagcccatc aagtgatgct ggcgtacttg ctgatttttt
    19801 attttgttgg cctgcttatt tactatagca agaaagtttc atgggatctg ttggatgtag
    19861 tgttgattgg aggggcagtt ttatttattg gcggagtcat ggttcatttc tggctaacgt
    19921 caaaagacgc attgttagct tctttgaata ccttatatcc aggaaaacgg gtaagtactg
    19981 gaggaaagtg gacgattggc gaattttttt ctttccttac aaattggaaa attccttttg
    20041 aagatatcaa ctattcgaat aactctgaag tggccctgtt ctatcacttt tttccaactg
    20101 tattcctagc aagtccattt gtgttatttg gcaaaaaaga tagcgaacaa aagttactgg
    20161 gacgtatttt gatgattttt tgtctgtttt ctatcttttg gattaccgtt gggttgccaa
    20221 aatggctagc agaaatcact ctgctgtctt atgttcctcc attaagagcc atccttactt
    20281 ttagttttgc ggcttgttta ttatcgatct ggtttatcgc ttatatttgg agagaagatg
    20341 ttattcctat ttggtataaa ttcattttgt tggcagtaaa tgcatggtct tatttctatg
    20401 cgattacgca ttcgaaaatg gataattatt tttcggattt tgaaaccatc gcagttgctg
    20461 tgttgggaac agtgatttta gcttttgcat tatttggctg gagacgcttg ttttacctcg
    20521 cttttgccgc cttagttatc gtatctggct ttttcgtcaa tccagtcgta gaaggtacag
    20581 gagcgatttt tgaaaaaaca ctggcaaaag aaatccaaaa aatcgatcaa caagatcctg
    20641 gtaaagtttg gttgtctgaa gatgaattat ataacttcac cccaacattg ggagtgaaat
    20701 ccttcaatac agtacgcttt tatccagata tagctgcatg gaagaaaatc gatccgaaag
    20761 aagaatacga gaagtattat aatcggtatg ctcatacaag agcttttatc gctaaggaag
    20821 atacaaagtt cattttagat cgtccagata tgttttcggt cacgttgaat tttgaagacg
    20881 cagaaaaatt agggatcgac tatgtgatca gtaaacgacc attaactgat tacaaccaat
    20941 tatatgaagc gcagttcacg cagctatatg gaccggataa agacggttat atgattttta
    21001 aagtagaata tccggattat ccagatgtac cacaaacaca aactcaggaa aatcagctag
    21061 tcgtacagta ataggctagc tgagaataat cctgaaatgt tagtagaaag gagagtggag
    21121 ataattcaag caatcgtaca aaaatttgtc aacaaaatga gtgtcggttt cttgcttttg
    21181 ttactgacgc tagtcttttt tgtttggaca gcagggttag gttttccagc aactttgttt
    21241 atatataaca atagttcatt acttatcgct tttagtgtgg ctattttgct cattttaaat
    21301 gtttataaag caaaaggcgt cgattttctt tatctaggtg ttgcgcttgc ccttttcatt
    21361 ttcttttctt actttcggga attaagaaat gagtctttat ttggagactt actgtttcct
    21421 ttgattattt tattttgttt agtaattaaa tggatcgagt ggacaaaatg ggatcgcggt
    21481 atttatctga ttgtcttttc ggtcttcctc ggaatcacgt tatatcgtgt atttacagag
    21541 atccaagtac cagaaggaca aagcatctgg gctccaggca attcgctttc tgatatttgg
    21601 atcaatacga atataatcgg aagttctttg atgactcttg ctttattgat cagtggattt
    21661 gccagttctt ttgaacgatg gtatgtacga atcatcggtg cagtagcagt tgttgcagct
    21721 tttctcggga tttgggtctg ccaatctaga ggtgcattag tcgcgttgat tgtttttgcg
    21781 atattggatc ttttacctaa atcgttgatg cgtgtcattc gtgcgccatt tattgcttac
    21841 acggttacga ttcttttagc tttgccgatt tcttatctgg cggctgtctc tgaaaaagtc
    21901 aatttgttta ccggtcgaga agatatttgg cataaattct atcagacgct aggagaaaaa
    21961 tctgaacaaa ttttactagg aatgaaaaca tttatcttcc aacgaggaaa ccaattttta
    22021 ggaaaccaca atagttataa ttctattttg aatatctatg gattgatagg atttgggatt
    22081 gctgctttgc tgcttatcct ttttattggt cgcttaacgt tgaaagcaga tttatccaac
    22141 gggcagatga cttttatctg ggcctttttt gcggtgatga tgcagtcatt tatggaggat
    22201 acattgactt catacccatg ggttccgatt atttatatcc tgttggctat ggccgttcat
    22261 cgatatgatg aaccagaagt tgcggaggaa ttctatgtta tggaagaggc atatgacgat
    22321 atgacttatg atgatacatc ttatgaggaa caaccagata gcgctcattc ttccaggatc
    22381 caacgctatc attgataggc acaaaatacg agagaggctg tgacaaccgt cgcagccttt
    22441 tttggtttat tgcaattgtc tagcatcttc tgtaaaatag aaacgttaga gaaaatcttg
    22501 tatcatagaa aattaagaaa gaaataagaa cgcagctcgg taccaaaaat atggtaaaat
    22561 ggcacttgac tgtaattcac tgaaaatcgc ttggaggaac acaaatgttt aaagatttgt
    22621 atttatttat gaaggacatt tatcagaaca gaaaattatt gctacagttt tcgatcaatg
    22681 acttcaaatc aagatatgca ggatcgtttt taggaatctt atgggcgttt atcaatccgc
    22741 tatttactgt attgatttat tggctggtat ttggtgttgg actgaaagca caaatgatcg
    22801 atgcaaaata cccatttatc gtatatttag ttaccgggat gattccctgg ttcttcttct
    22861 cagatgcatt tgcatcaact acggttgttt ttcgggaata tacttattta gtaaagaaag
    22921 tcgtattcaa tattcgtatc ttgcccacga cgaaaatcct atccaatctg tacacccact
    22981 tattcttcat tctgattggc atagctgtcg cgcttataaa tggtatatat ccttcagcaa
    23041 tgtctttaca gctgatttat tatttatttt gcatgtgtgc tttcttgaca ggattgactt
    23101 ggctgacggc atcgatccaa ccatttttac ctgatatcat gcaattaatt acgatcgtgc
    23161 tgcagttgat catgtggaca ttaccgatat tatggagccc taatcagttt gattcaggtc
    23221 ttgtaagcat attgaaatta aatccgctgt actatgttgt tcaaggttat cgtgagtcat
    23281 ttttaagtga agcttggttc tgggagcatg gaacatatac tttgtatttc tgggttttca
    23341 cgttagtaat gttcgtaatc ggctctgcag tgttccgtag attgaaacca catttttcag
    23401 atgtgctgta aggagaatag ctatgacaga atatgcaatt agactaaaag atatcacaaa
    23461 atcttataat atgtacgcaa aaccttcgga tcgatttcgt gaagccctca atccttttaa
    23521 gaaatcctat catgatgtat tttatgcgtt gaaaaacgtg aatgtagaaa taaaaaaagg
    23581 tgagatgatc ggtttcgtgg gagaaaacgg atcgggaaaa tctacaatgt tgaaaatcat
    23641 tacgggagta ctgacaccaa catccggcac gatggaaatc gaaggaaaaa tctcagcttt
    23701 gctagaacta ggatcaggat tcaatcctga gtattctggc tatgaaaata tctatttaaa
    23761 tggaatggtt ctaggatttt caagagaaga agtcgatgaa atggtcgatg atatcattga
    23821 atttgctgac atcggagacc atatttatca acctgtaaaa acttattcaa gcgggatgtt
    23881 cgttcgtcta gcttttgctg tagcaatcaa tgtgaatccc gatattttga ttgtggatga
    23941 agcattggca gtaggcgatc ttgaatttca actaaaatgt atggaaaaat ttacagaaat
    24001 caagaactcg ggaaagacga ttttattcgt ttctcatgat atcagttcga ttcgtcgttt
    24061 ttgtgatcgt tcctattggt tgaaaaacgg agaagtcgtc gaatatggcg atacgatgga
    24121 agtaacgacg aattatgaaa actttttaaa gaaaaaatca gttaaaacag tggatcggaa
    24181 taaaaaccaa gtagaacggt tcgccgctcc agatatcgtc gacgtgacga aagcggaatt
    24241 gttggataaa gacaaaaatc cggtggatat gctggaacaa ggagaaaaac tatacgttaa
    24301 agtaacttat gaagtaaaag atgatacaat caaaaatccg gttttaggaa ttgcgctacg
    24361 aacagtcgac aatttttatg tatgcggact taatactcta ctagatggta tcaagattcc
    24421 ttggaaaaaa ggagagaata tcttttatct ggagtatgaa aagttaggtt tgttagctgg
    24481 tgaatattat tttgacgttg cggtctttga agaaaatgca acggttcctt tggtatataa
    24541 gacaaagtac atgaacttgt ttgtcagcgg ttcttatatc ggagaaggca tcgtggtctt
    24601 agaccataaa tgggaagaag ggactcatag caatgaaata tgattttgaa atggacctag
    24661 atgaacaaag cagtgtggga aaaattgccg cacagatcaa accaggaagt aaagttttag
    24721 agtttggtcc cggaaacggc cgattaacga aacatttaat cggagcaaaa caatgtgaag
    24781 tgagcattgt tgagttagat aaggaattgt tcgattttgt cagcgaattt gctcaagatg
    24841 gattttatgg tgatatcgaa agttttgagt gggcaaacta ttatgctgga cagacatttg
    24901 attacgtctt gtttgcggat gttttagaac atttggtaga tcctggaaaa acattgaaga
    24961 aagtcagaga atttttgaat gaagaaggag agatcctgat tacattccct aacttggcgc
    25021 ataattctgt catgatcgat ttgttcaata accaattgcc gtgggcttct tatggtctcc
    25081 tagatgaaac ccataattct ttttatactc atgatggctt ccaaaaagtt tttgaaaaag
    25141 cgggattatt cattaatatt gaagattatt tgtacttagc tgtaggtgat acagaattaa
    25201 aatcaactta tgaagaattg ccggaagctg tacgctatga tttcaaaatg cgaccatttg
    25261 gtgaagtcta ccaatacttt ttctcattga tgaaacatcc agtagcacaa agttccattg
    25321 cagagccaca aaattctaat tatgtaaaag tgttagaagt aacccagcaa acgaaacaag
    25381 atgaaacaat ccaacaaata ccattcaata atttcacagg ggaaaatgag acactaagtt
    25441 tccccgtatc agaaacaaca gaaagaatgg tgtttcgctt cgcgcaacaa cctagcttta
    25501 tcgaattcag cgcagaagct gccggagaaa aactaacatt tatcgattcg aatgctgtag
    25561 tcaaaacagt aaatgattgt tatttgtttg atgggaaaga attaccagag ttcgttctaa
    25621 cggatatttc tgggaaagaa gtgactatcc attgtcacta tcgctttatc ggggaattga
    25681 caccaacaat gaaagaattg ttggaaacga ttcgtcccat ggctgaagtc acaaagcagc
    25741 tttctgagaa aaatgacgaa ttagaaagag aaaatcatca tcttcttgag gaaaatacaa
    25801 gactagacca tacgttaaaa acaaccacaa atcgctattg cacattgttg gaaagtgatg
    25861 aatggacaat aaaacataga ctaggacgac gtaagaaaga aacttcgaaa aaaatccaag
    25921 aaaaagaact ttctatatgt attgacgaga aaatctggga tgcagaaaca aaaatattaa
    25981 aaatcatcgg atggggaatc gctaattcgg atcgccagcc cttgtcctat aagttatcag
    26041 ctgaccaatc gccatttttc gaagcaattc ctgtttcacg agaagaagtc aatcaagcag
    26101 aacagctcgc aaaaggaaca gaagcgggat ttgagttacg aatcctttgc gagcaagaac
    26161 gttcattctt agtggaagca gtagctcaaa atggccaatc atggatcatt gaaatgtaaa
    26221 taatgattaa cttataaaga taaggagtaa acgaatcgtg caaaaaaaag aaattgccgt
    26281 atttatcgat caaatcactc gtgaacgggc cactggcgat ttgcttattg tgggctgggc
    26341 aattgatgaa gtgaccaaag aaatccctac gataaaggta gaaaaagaaa atgtgattgc
    26401 tgaagcaaca catgtcgtaa gattggatat caatcattta tataatcttg atgttaagac
    26461 ccaaagcggt tttaaggtac gtttatcagg gaaaatgaga ggaaaagcca tcttagactt
    26521 ccaaacagcg agacatcaaa atggcatagc tgtgaaatta aacggtaaat acccttatga
    26581 tgacggcatt gaatcttcat gggaaagaaa aaaaagatta ctgaaaaaag ggataaatta
    26641 tgcaaggact catggcgtaa aaaaagcgat ccgtcgggtc aaattggaat tgaagccagg
    26701 atcgatcgac tatgcagagt ggatcagtcg tcatgagaaa ccagatttga aagagcaaag
    26761 gaaagaagca caaggatttg cgtaccgtcc attgatttcc atacttatgc ctgtctataa
    26821 cgttgaaatc aaatggctcg aaaaatgcat tgattcggta ctggatcaaa cgtatgatca
    26881 ttgggaacta tgtatcagtg atgatgcttc tactgatcca gctatccgaa agtgtctgga
    26941 atcctatcaa gcaaaagatg atagaatcaa agtcgttttc cgaaaagaaa atggacacat
    27001 cagtctggca actaattctg cattggaaat agcagaagga gaatttatag cactcttaga
    27061 taatgatgat gaattaccgc catttgcatt atatgaagtg gcaaaagtgc taaacgtaca
    27121 tccagaactg gatgtgatct acagtgacga agataaaatc gatgcagatg gcaatcgctt
    27181 tgatccgcat ttcaaagcag actggtcgcc tgatacattg atgggaaata attatatctc
    27241 tcacttaggc gtatatcgaa caagcattgt taaagaactt ggcggtttcc gtaaaggcta
    27301 tgaaggttct caagattatg atttggtcct tcgtgtgaca gaacaaatcc ctgcagatca
    27361 tatttaccac attgaccgag tcttgtatca ttggcggacg atcccaggat caactgcaag
    27421 taatggcgaa gccaaaagtt atatctatga ttccggagtg aaagcattga cagatgccct
    27481 gtctagaaga aacatcaaag gaagcgtacg tcctggcaga atttctggat tttatgagat
    27541 tgcttatgac gtcttgcaag aggatttggt cagtgtgatc attccaacga agaatggcta
    27601 tgaagatcta aaaacttgtg tggattcgat catcgaaaaa acgtcttatt caaattatga
    27661 aatcattatt gcggataacg gaagtacaga tccaaaaatg caagaattat ttgcagaata
    27721 caagcatcag ctgaaagacc gctttatcgt agaattgatt gacattccat tcaattattc
    27781 tcgaattaac aatttagcag cagaaaaagc aaacggcaaa tactttttat tcttgaataa
    27841 cgatacagaa gtgattgagc cagattggat gacggtgatg gtttcttatg cacagtttga
    27901 tcgaatcggc tgtgtaggag caaaactgtt ttatccagat gatacaacgc agcatgcagg
    27961 agtattatta ggaatcggtg gtgttgcagg gcatgcattg aataactatg atcgaacaca
    28021 ttgtggttat ttcggccgat tggtcattga cgtcaattac ttagcagtca ctgcagcttg
    28081 tatgatggtc aaggcagctg acttcaatgc tgttaacggg tttgatgaaa cattagaagt
    28141 agcattcaac gatgttgact tgtgcttgaa agtttatgaa ctgggtcgtt acaatgtcta
    28201 tgcacatcaa gcagaattgt accatttcga atctaaatca agaggttatg aagatactcc
    28261 agaaaaacaa agacgttttg ctggtgaaat caaaaaaatg caagataaat ggccagcata
    28321 tattgcgcat gatccatttt acaatgataa tttaacaaaa gaaggaatcg gcgacttttc
    28381 gttgagacca gattaaacta taataaaaag ctgttatgtt gtgattcgct cgcacataac
    28441 ggctttttat agttttttgt caaaaaaagg cagaaggtgc cgactcaaaa aaataagtcg
    28501 aggttgggac agaagtgttt aactccgaga aataagaaga aattcacgaa aattgctttt
    28561 caaatttttg tgaatttcgg cttatttaag aagaagttgc ttctgctccc accgtttatt
    28621 cgtttttaaa gaatgagaca aaagtgtttc ttacttttgt cccacgctct tattcatgct
    28681 cagagcgcca atagatacaa aatcatagcc aaagtttcac gaaccctagc tgtcaaagaa
    28741 tcgatatttt attttaatat aggctatttt aaaataaatg gtttaaggta ttcctctaca
    28801 aaagccactc tatcaattat catgggttta aaataagaag tgatggagat aaccagattg
    28861 ttcttagcgt caatataaag aacatttcca ctattaccaa ttgctgaata tatttcgttc
    28921 tcagaatcta atacccacca taaatagcca tatctcatat tttgtaagtc ttctaaagca
    28981 ctggttctag gtttgaacat ctcgtttatc cacatgggtg gtacgatttg ttttccttta
    29041 tacatccctt tatttaggca taatacacca atttttgcca gatcacttgc cgataaacac
    29101 aaaccatatc ctgccgtccc gatatttagt ggatcacaaa accagacatt ggttttagga
    29161 gacttatcca ttgtaaactg cttatgttct tcagctgttt cagcataata attgacatgg
    29221 tttggtatcc ctataggatc aaatagatac ttattggcaa aatcaacagt tgttagctta
    29281 cttgtctgat acaacaagcc agttaatatg tgtaaacaga cagtttgata gttgaattcg
    29341 ccggttatac cttttcttcc tcccaataaa tctagtgatg tttttgtcca atcttcactt
    29401 gaacagactt ttgtccatgg atcgccttta catttgtagg gtgctttcat tgttagcaag
    29461 tgcttgattg taatagcgta aatagttttc tccccgcgtt tcactttata ctctggaaaa
    29521 taatctaata ctttatcatc gatacttttg attaatcctt gctctaaagc aatgccaatc
    29581 agcaaagata caatactttt cgttgctgac atgatatgac aagtatcgtc ttttttataa
    29641 ccattccatt catctgtata aacttctacc ccatccttat atgcgacaat ttgacatata
    29701 tttggttgtc gaaaaccaat aaaatcatgc aactcttgtt tattcataag atattacctc
    29761 actttcttct ataagcataa tgtcattaaa aatcgatttc aattttttcg attcttcacg
    29821 taatacaggt attcttatgg actagacagc gctttgggaa gatggattct ctgaaaaata
    29881 taaaggttca ctttatgagt ggataaaaaa agcagcaaat acttcgactt ctttaattta
    29941 ccaacattag tgaaaatcga ttcatctgga gatttgtaat ttagagtcct tgtcttgatt
    30001 agaggtgtat aaagcttttt attagacatt tttaaattcc attacaattt gcttataaac
    30061 taggttttta aaggtgacta tggtaagata atagagatat tattttgtga ttaggagtgt
    30121 atatatgaat aaaaatggag aatggagtgc tgcacgacgg atattcatta tattaatgga
    30181 tgttattgta tacaatgcag caatatatag tagtttctta ctgaagtttc gtggagagat
    30241 cccattacga aatttagaaa ctttccaaca ctcagcaatt attatttcag tgatttttat
    30301 tgcgttgaac attttgttgg gtgcatatgt tttttataat cgaatgatca gtgacatcgt
    30361 gtttgtcaca gtcatcggtc aggtattgat gacactaggg atcatggtag tgacttttgc
    30421 gggccgctgg tttgcttttc cacgtcttgt tatcttactt tcatttgttc tcggtacgct
    30481 tttcttaagt atctatcgta ttctcgtata taaactttat ttacgcgtaa gtcgagataa
    30541 aaaggtcgtc attattgggt tagaaaagga tgtcgcacca gcaatccaaa attttggttc
    30601 aaagaaaaac aacaaacata aagtcgaagc agtcattctt gataactatt atgcaaacat
    30661 caaaaatatg attaaagaca tcgatattgt ctatcttgct tctcatatcg aagaaactga
    30721 aaaaatcaaa atctatcaat tagttactaa aaatgaaaaa aaattgtttt tgaatacaac
    30781 atttgaaaac ttgacattga tcaatccaaa tattatgaat ttcgaagatg aaagtattat
    30841 tgaagcatct ggatttagaa tccaacctga atatgaacta ttcaaacgtt tgtttgatat
    30901 catcgtttca cttgttttat tagttattgc ttcaccattt atgttattca cagcaatttt
    30961 agtcaaagtg acatcaccgg gaccaatcat ctataaacaa gtgcggatca caaaaaatca
    31021 aaaggaattt tcaatctata aattccgctc gatgaccgcc acagccgaag caaaatctgg
    31081 accagtttta gctaagagca atgatgcacg agtaacgcct gtaggtaaat ttattcgagc
    31141 tgtccgcttt gatgaattac cacaaatctt caatgtgctg aaaggcgata tgtcgatcgt
    31201 aggaccacgt cctgaacgtc ctttcttcgt cgatcagttc aatgcagaaa acccttatta
    31261 ctacttacgg cataatgttc gtgctggtat cactgggtat gcacaagtct atggaaaata
    31321 tgtctctgat tacaacagta aattacgttt tgatttactt tatatcaaaa aatattcatt
    31381 gatgcttgat ttaaagatct tgctgcaaac catcaagatc ctatttgata aaatgtcccc
    31441 tcaaggactt gaagaagacg aaaatgtgat ctcattggca gaaattgctt ttccgaatga
    31501 aaaaatcttt cgctagttgg gaggcgtaaa aatgaacaat ccgaaattca gcataatcgt
    31561 accagtatac aatgcagaag caactattgg tcgaacgatt gatattctaa aagaattgga
    31621 ttatgaagag tacgaagtcg ttttagtaaa tgatggatca acagatcaaa cacaggaaat
    31681 cattcaagaa ctgattgaaa atgatgaacg ttttgaattg attactacga ccaatcaagg
    31741 gcccggatta gcaagaaacg aaggaataag acagtcaaaa ggagaatatc tcttattctt
    31801 cgatgcagat gacacgccag taaaaacgat cttgtcagat tatgatcatt tgctagaaaa
    31861 gagtccaaaa gcggatcttg ttgttagttc gtttgttttt cgtacaatgg acgagggaag
    31921 aatcgtttcc gaaaaagaaa acttagttac agaatgtcac tatctaactc acgaagagtt
    31981 tataaaagac atgtatcagt taatgaatga acagttgatg tatgttgtat ggaacaaatg
    32041 ctatcgtagc gatattctga aaaataacca aattctattt aaaacttata atagttgtga
    32101 ggatcgaata tttaacttac attattatga atactgtcat caagtgatca tgaacccaaa
    32161 agtagaatat atttatgaat ttgaaggtgg gaaggggatc actaatcaat accgacctaa
    32221 caagttcgaa acatttaaag aattctattc attagcaaat actgtaacag acgatattaa
    32281 taaagacggt atggcggcgc ttcttttaaa agggacaact tcagttattt tttctattta
    32341 tagtacctct gcaagaactt caaaagagaa gaaagacgaa gcaaagcaga tattgagtga
    32401 tccagtgatc cgagaagcca agcaaattgc taagacggat tcttcagcaa aaaaaataac
    32461 aaagttgctt tacaatatgc cagctccact atttttatct gctgtaaaag ttggaagctt
    32521 cgttgaagtg aaaatgccag ggttaatggc tgctttgaag cgagtatatt agttaatgga
    32581 ggaaaatata atgaaaagaa ttttgcattt tcagggacga atgggtttag gtggagcaga
    32641 gtctttcatg atgaatttat atcgtaaaat tgatcgtaca aactatcaat ttgatttttt
    32701 gatttatgaa gattatgcag atgttcaaga ctatcattca gagattgaaa gattaggagg
    32761 ccgtattttt gttgtaccta atcctaagaa aaatattttt aaatatttaa tagaagtgaa
    32821 taagttacta aaaaaagaat ctttttctat agttcacaat caggtttatt ttggcggggg
    32881 aattaattta tggttagcca aaaagaatgg aatcagacag agaattgctc atagccatgc
    32941 aactgaagat ggaaaatctc aaaatattgt aatgaatgta ttgcgtaaat ttttaaccaa
    33001 attgttgtta caaaatgcaa cagactacct tgccgttagt caagaagctg gtgaaagtct
    33061 gtttcaaaac cacccctttg agatagttca taatggtatt gatttagagc tttatagtaa
    33121 aaattcagaa gctaaggtta ataagagaaa agaattggat atctcaatga gtacttttgt
    33181 tgtgggaaac attggacgat tagagaaaca aaaaaatcaa tcttatttgt tagagatttt
    33241 tttagaaata ctaaaaatga attctgattc ttacttgatt ttagtaggtg aagggtcact
    33301 tagaaataaa ctgaaagcca aagcagtaga attggatata gagaaaagag taaaattttt
    33361 aggagaaaga aacgatattc ccgagttatt atctgtgatg gatgtttttg taatgccttc
    33421 tctttatgaa ggtctgccaa tggttggatt agaagcacaa gcagcaaaat taaaattagt
    33481 cttagcagat actatttcca aagatacaaa gttaacaaat aatgtggatt ttgtatcatt
    33541 agatgaaaca ccacaagaat gggcaaaaaa agtaataaaa gagccgtatg ctaataaaat
    33601 aacacaagaa ctaaagagtt atgatgtttc gtacactact gaacaaatgg agagtatata
    33661 tagtagagat cattaaaaat gttcaagata ttttaggagt gattattttt gaaaatatgt
    33721 tatttgatat tggcatacaa tgatattggc aacttaaaga gattggtcaa tcgattgaac
    33781 gaaaatgcag tttttattat tcatatagat aaaaaaactg atatagaacc atttattgaa
    33841 gcatttaaat catatgataa tgttgaattt ttatgtaata aaaaccgtgt taaaatttat
    33901 tggggtggtt tttccattgt acaagcagaa atcaatttag taaagagagc attacaaaat
    33961 gagaaatatt taaaatatgt attattatct ggtgctgatt atccaatcaa agataatgag
    34021 tatatttata attattttaa aaagaatagt tcagtggagt ttattcgtgg aatagatcta
    34081 gatcaaatta aac
//
LOCUS       DACGEU010000022        33262 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.022, whole genome shotgun sequence.
ACCESSION   DACGEU010000022 DACGEU010000000
VERSION     DACGEU010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 33262)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33262)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33262
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.022"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(40..228)
                     /locus_tag="IXR40_000976"
     CDS             complement(40..228)
                     /locus_tag="IXR40_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HAQ4360842.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            498..860
                     /locus_tag="IXR40_000977"
     CDS             498..860
                     /locus_tag="IXR40_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAQ4360843.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            912..2594
                     /locus_tag="IXR40_000978"
     CDS             912..2594
                     /locus_tag="IXR40_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HAQ4360844.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKETPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            2711..4747
                     /gene="recG"
                     /locus_tag="IXR40_000979"
     CDS             2711..4747
                     /gene="recG"
                     /locus_tag="IXR40_000979"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HAQ4360845.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKEFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LLTGSTKAKERRELLEKLEQGEINIVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            4796..5797
                     /gene="plsX"
                     /locus_tag="IXR40_000980"
     CDS             4796..5797
                     /gene="plsX"
                     /locus_tag="IXR40_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HAQ4360846.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            5919..6161
                     /gene="acpP"
                     /locus_tag="IXR40_000981"
     CDS             5919..6161
                     /gene="acpP"
                     /locus_tag="IXR40_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HAQ4360847.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            6429..7433
                     /locus_tag="IXR40_000982"
     CDS             6429..7433
                     /locus_tag="IXR40_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4360848.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            7434..8378
                     /locus_tag="IXR40_000983"
     CDS             7434..8378
                     /locus_tag="IXR40_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4360849.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            8378..9340
                     /locus_tag="IXR40_000984"
     CDS             8378..9340
                     /locus_tag="IXR40_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4360850.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            9367..10281
                     /locus_tag="IXR40_000985"
     CDS             9367..10281
                     /locus_tag="IXR40_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4360851.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            10307..12088
                     /locus_tag="IXR40_000986"
     CDS             10307..12088
                     /locus_tag="IXR40_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HAQ4360852.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            12436..13122
                     /locus_tag="IXR40_000987"
     CDS             12436..13122
                     /locus_tag="IXR40_000987"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HAQ4360853.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            13142..16723
                     /gene="smc"
                     /locus_tag="IXR40_000988"
     CDS             13142..16723
                     /gene="smc"
                     /locus_tag="IXR40_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HAQ4360854.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIEAALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            16732..17541
                     /locus_tag="IXR40_000989"
     CDS             16732..17541
                     /locus_tag="IXR40_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAQ4360855.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            17552..18550
                     /gene="ftsY"
                     /locus_tag="IXR40_000990"
     CDS             17552..18550
                     /gene="ftsY"
                     /locus_tag="IXR40_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HAQ4360856.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            18737..21004
                     /gene="gshAB"
                     /locus_tag="IXR40_000991"
     CDS             18737..21004
                     /gene="gshAB"
                     /locus_tag="IXR40_000991"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HAQ4360857.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKKYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(21093..21545)
                     /locus_tag="IXR40_000992"
     CDS             complement(21093..21545)
                     /locus_tag="IXR40_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HAQ4360858.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            21695..22645
                     /locus_tag="IXR40_000993"
     CDS             21695..22645
                     /locus_tag="IXR40_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HAQ4360859.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            22638..23597
                     /locus_tag="IXR40_000994"
     CDS             22638..23597
                     /locus_tag="IXR40_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HAQ4360860.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            23594..24349
                     /locus_tag="IXR40_000995"
     CDS             23594..24349
                     /locus_tag="IXR40_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAQ4360861.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHLGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            24372..25325
                     /locus_tag="IXR40_000996"
     CDS             24372..25325
                     /locus_tag="IXR40_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HAQ4360862.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(25969..26265)
                     /locus_tag="IXR40_000997"
     CDS             complement(25969..26265)
                     /locus_tag="IXR40_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HAQ4360863.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            26620..26976
                     /locus_tag="IXR40_000998"
     CDS             26620..26976
                     /locus_tag="IXR40_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HAQ4360864.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            26986..27885
                     /locus_tag="IXR40_000999"
     CDS             26986..27885
                     /locus_tag="IXR40_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HAQ4360865.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
     gene            28402..29133
                     /locus_tag="IXR40_001000"
     CDS             28402..29133
                     /locus_tag="IXR40_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HAQ4360866.1"
                     /translation="MMKKEIVLTAAMMLFSMVASTTFVSATEVYPKEYNTEGTITFEA
                     GDEGVTPPVDPENPDPNKPVDPSDPPSPGTGGALSIDYGSKFKFGTQKISTADKTYYA
                     AADVMNDGSRKPTYVQVTDRRSTLSGWKLSVSQPEQFKTASGDELVGAQLKFTKGQAV
                     SLVDPTYTPQTVNSELTLTPGGNNTLAINAKSGTGVGTWVYRFGANENENQDAVQLSV
                     PGKSVKLAQQYSTKLVWTLEDTPNN"
     gene            29278..31305
                     /locus_tag="IXR40_001001"
     CDS             29278..31305
                     /locus_tag="IXR40_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lectin"
                     /protein_id="HAQ4360867.1"
                     /translation="MKKRRIVLILSSLLVTNIFPIIGYSLELNQLEHGNRRDEESKLT
                     STFDSLIESNQTQESSEDLSISSSGETTDNVEAEGSDKQGLEDAPISAVELPDDPNII
                     SIDKIFQTPIGTSTSILENGKLLQLNPAERSQRGAIWSNKKISLLSDFTFKSYLYLGN
                     QRDRAGDGMTFTLTGDPRMASNPSQVIGSPGMGIGSYSTRSGQPYIANALSIEFDTYK
                     NSGSSDRMDREITADNRGHGHVAFVTPKPNNNNYSGEHTGVTVAPTFLSNGTWRLLII
                     KWDAEQRSLTYDLEGVGRSSRIIPDLIRQFGSTEVNWGFTSSTGTFFQENAVAVTRLP
                     SNVTSTADVKVNDSDYGAIAEAGGNDKITIRNTLKVEGDFLEYKKMQTSIDLPQELTI
                     PEHILINGNQIDAKDILITGNRVTLNLTDYFIAGDTLIIELETTLQEVIPEKVLTMHF
                     EYLENGNLIEQSNEINLKIAKLKEIDIHVYYKDKDSQIDIAEMKTITGKIGEKYKETP
                     IDIEGYVFDSDSANTEGIFSENTEDIYFYYRKGKLYLSTAPQYVNFGKHKISSRPLSE
                     FGQFSGGLKIIDERAFGSWKLQLKQEKVLTNGDFELPEALSFVTSENTTVIGTSAVTI
                     FESDQKGESDLSSLLDSTAHRGIRINIPVENQRIGTFEGKLSWILADVPGN"
     gene            31413..32510
                     /locus_tag="IXR40_001002"
     CDS             31413..32510
                     /locus_tag="IXR40_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HAQ4360868.1"
                     /translation="MIKGAIFLRPKQQLFITLLVILGALFNNISVSASAFNFSVTPIT
                     SENQIDKRKTYFDLQLDPDQEVEVKAELRNDTEKEVKIDISVNSATTNSNVMVEYGKN
                     EIEKDMSLIFDLVDYVSYPQIVTLKPKSVQTVAFHVRMPNERFDGVLAGGITFQEIQT
                     EKDQTETKDQSLSIENEYTYIIALLMQQTLNEVAPNLTLHEVKPDQINARNVILANVQ
                     NDQKTYINQVVIETKITKKGHSEVLYQEEKEGLQIAPNTNFSFPTALNGQPLTPGEYH
                     LTMTVLGNENENGKFSRKKGNTTINYTNQWVFEKDFTIDGKVAKELNTTDVTIKKDNN
                     WIYILVASLFLLFILLCILLFVLRKKEEKEK"
     gene            32817..>33262
                     /locus_tag="IXR40_001003"
     CDS             32817..>33262
                     /locus_tag="IXR40_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAQ4360869.1"
                     /translation="MNYEFFLSKEDHRSYSLLKYLEASSNLSESISNVQEELSLSTFL
                     LKKTIDKLKHDLQKFDLEKNLRVTVSELDICLEINGKCSSKALLSRYITDSLSMKMVL
                     AFFQEKYISVENFAKQHHVSYSVAYKVLQRLKRNLKKYQIFFEKRK"
BASE COUNT        11137 a         5762 c         7123 g         9240 t
ORIGIN      
        1 aaaaccgttc actatctgaa cggtccaagt atcattcaat taaacgcgtt caacttttcc
       61 tgatttcaaa gcacgagttg acacccaaac ttttttaggt tttccgtcga ccataacgcg
      121 aactttttgt aagttaggtt taacagtacg ttttgttgag ttcatagcgt gtgaacggtt
      181 gtttccactt tttgtcttgc gacctgtaaa gtaacaaact tttgccatgg taatttcctc
      241 ctttgccttg atttggagca atagaataat tcagctcata ccagactaac atatcatata
      301 gaatggaaat ttgcaagtac attttcatag atacaattga caattgagaa gaataattgt
      361 aaattaaaca aggttatacc tgaaattttg caaggttttt gagtactttg ggtaactgcc
      421 ttttatttca agttgcgcta tgataaaata tgatagaaga aaaatgggag ttttttaccc
      481 gttaaggagg ctcattcatg gctgtaaaaa ttcaaacgtc agctggaacc attgaaatta
      541 ccaatgatgt aattgcaaca gttgttggtg gcgccgcgac agatgtgttc ggtgttgtag
      601 gaatggccag caaaaatcaa attaaagata atattactga gattttgcgt aaagaaaatt
      661 actcaagagg agtagttgtc cgccaagaag ataatggtat tgctgtagat gtttatacga
      721 ttatcagcta tggtacgaaa atctctgaag tttcccgcaa cgtccaagaa aaagtgaaat
      781 acaatctaga ggcattatta ggcgtaactg ccaattcagt taatgtcttt gtacaaggtg
      841 ttcgtgtact gccagactag gcaggagact ggctggtaac tcagcagtcg atctgaagga
      901 ggattatcta ggtgagtgta acagaaataa gtgcaagcca gttccaggaa atggtccagg
      961 caggtgcgaa tcgtctgcaa gtaaatgcag aatacgtcaa ttcattaaat gtattccctg
     1021 tgccagatgg cgatacggga acaaatatga atctatctat gactagtgga gctaaggcag
     1081 tagtagattc aacctcagaa aaagtaggag aattagcagc aatgctttca aaaggattgc
     1141 tgatgggtgc gcgcggaaat tccggcgtta ttttgtctca attgtttcgt ggattttcta
     1201 agcaaattcc agatgttgtc tcattaaatg cttccgatct tgctgcagcc ttcactcatg
     1261 gagttgaaac tgcgtataaa gcagtaatga aaccagtaga aggaacgatt ttgacagtag
     1321 ctagagaagc agcgaaagct ggagaaaaga aagcaaaaag tactgatgat gtcgttgaag
     1381 taatgacagc tgttgtaaaa ggggcaaagc gtgctttagc taaaactcca gacttgcttc
     1441 cagtcctaaa agaagtcggt gtcgtagaca gtggagggca aggactgctg tttgtttatg
     1501 agggcttttt aagtgcattg aatggagaat tccaagcgga tgaaacatat gaaccttctc
     1561 cagcagaaat ggatgatatg gtcaatgcag aacatcatcg cagtgtccaa ggtcaaatgg
     1621 cgacagaaga tatccatttt ggttactgta cagaaatcat ggtaaaaatc ggagaaggac
     1681 ctacagtcga tagtacattc gattacgaag aattccgtaa ctatttagat ggtataggag
     1741 attctttact tgtggtcaat gatgacgaga tcatcaaagt ccacgtgcat acagaaaacc
     1801 caggagaagt cttgaattat ggacaaaaat tcggttcatt agtcaaaatc aaagtcgaca
     1861 acatgcgctt gcagcatgag acgattttgg aacacgatga agaagtgaac gagtttgcga
     1921 aaaaagaaac accacgtatc ccgtatggta tcgtagcgat cgctgctggt aaaggcgtcc
     1981 aagagctgtt tgaaagttta ggcgctaatt atgttatcag tggtgggcaa acaatgaatc
     2041 caagtacgga agacattgtt aaagcgattc aagaagtaaa cgcagataaa gtgattgtct
     2101 tgccaaacaa taagaacatc ttcatggcag ctgatcaagc agcagaagta gcagatatcc
     2161 cagtagcagt tgttccttca agaacgattt cccaaggatt gacagctatg ctttcattca
     2221 atgatcaagc ttctttagaa gaaaacaaag aaacgatgac agaaatgttg tctagcgttg
     2281 tgagcggtca agtcactcac gcgatcagag atacctcaat tgacggtgta gagatcaaag
     2341 aaggagactt tttgggcatg atcgatggaa aaatcctgat ctctaaccca gatatcacag
     2401 caacagcgtt aagtacacta gaacaaatga tcaatgagga cacagagatc gtaacgatct
     2461 tggcaggtga tgaaggaaca gttgaacaag caaatgaatt tgctgagaaa ctaacagaaa
     2521 aacatcctga tttggaaatc gagatccacc aaggagatca gcctgtctat ccttatctat
     2581 tttctgctga ataatttctg tgtcagaata tctttctaac acagtattca ttcataaaag
     2641 gccttcggtt agtgatcagg tatgatcgct gaccaagtcc tttttttgtt aagggaggga
     2701 ggaaaaattt atgcgttctt tagatgatcc aatcactatg ctggcaggag tcggagaaaa
     2761 aagagcagct agtcttgcca gcttgggcat ccaaacgatt gaagacttac tgacttatta
     2821 tcctttccgc tacgaagata ttcaggaaag aaatctaaac gagatccaag atcaagaaaa
     2881 ggttactttg aaaggaatcg tagtctcgcc tcctgtgatg aatcgatttg gttataaaaa
     2941 aagccgattg caatttcgta tgatgcaaga acatgatgtg ttcaacgttt ctttttttaa
     3001 tcaaccttat ctaaaagaaa aagtcatttt atcggaggaa atcgccgtat acggtaaatg
     3061 ggatgcaaag cgtaaagcat tgaacgggat gaagatttta ggttctcaaa caatggatga
     3121 cttttcgccg atatatcacg tcaacaaatc aattcgtcaa acgacattag ttgatctaat
     3181 caaaaaaggg tttcaagaat acggcacatt gattgaagaa aatctgccaa acaaccttgt
     3241 ggagaaatat cgactgcttg accgagcttc tgctgtaaga agtatgcatt ttccaaaaga
     3301 ccacgaagaa aaccatcaag ccaaacgacg tgtcgttttt gaagagttct ttttatttca
     3361 aatgcgtctt caaggattga aaaaagcaga aaaagcagaa acgaatggtt tggagatcct
     3421 ttatgatgtc caaaaattga aagaatttac tcaaaagcta ccttttgaac tgacaaatgc
     3481 acaaaaacgt gtaacgaatg aaatctgtcg ggatcttcgc agtccgcagc atatgcagcg
     3541 acttttgcag ggagatgtag gtagcggaaa aacagtggtt gccgcgattg cgttatacgc
     3601 taccgttaca gcaggtttcc aaggtgcgtt gatggtgcct acagaaatct tggcacaaca
     3661 acatatggaa agcttgcaac agctgtttga tcccaatgaa gtaaccatcg cattgcttac
     3721 ggggtcaacg aaagcaaaag aacgtcgtga gctccttgaa aaactagagc aaggggaaat
     3781 taacatcgtg atcggcacac atgcattgat ccaagatgga gtcgaatttc agaatttagg
     3841 tctagttatt acggatgagc agcaccgttt tggcgtgaac cagcggaaag tacttcgtga
     3901 aaaaggctgg cgaccagatg tcttatttat gacagcgact ccgattccta gaacattagc
     3961 tattacagca tatggtgaga tggatgtatc tatcattgat gaacttccag ctggacgtat
     4021 cccgatcgaa acacgctggg taagaacacc tcaattggac agtgtactgg attggacgaa
     4081 aaaagaactg gcaagaggac atcaaatgta tgtcatctgt ccgctgattg aagaatcaga
     4141 agcattagat gtaaaaaatg cagtggaaat ctatgaaaaa cttcgtgaac tatttgcacc
     4201 aaaatatgaa gttggcttgt tacatggtaa aatgaagaat caggaaaaag aagtaatcat
     4261 ggaagccttc aaagacaacc agatgcagat attagtttcg actactgtaa ttgaagtagg
     4321 ggtaaacgtg ccgaacgcga ccgtcatgct gatcatggat gcggatcgat ttggattggc
     4381 acagctgcat caacttcgtg gacgtgttgg acgcggaagt gatgcttcct actgtatctt
     4441 agttgctaat cctaaaaatg aactaggtgt ggaacggatg aaaatcatga cagagaccac
     4501 caatggtttt gtactaagcg aaaaagatct ggaattacgt ggtcctggtg aagtatttgg
     4561 cttccgtcaa tctggtctgc ctcaatttgc gattgctgac ttggtgacgg atggaaatgt
     4621 tttggaggta gccagagaag aggctgcagc cctttggcag ataaaggatt ggcagatgct
     4681 tcctgagtat cagcctttag cgcaaagcct ccaaatagaa aatcaggata atcgttattt
     4741 cgattagcag actgtgctat actttatact gatgacggaa aaaggagtgg aaacaatgaa
     4801 aattgccgta gatgcaatgg gcggagatca cgcacctcaa gcaattgtag aaggcgtggc
     4861 tttagcgcag caagattttc cagaagtaga attcttactt tacggaaaag aagcagaaat
     4921 caagaaatac ttaacaaatg aaaaaaacat cacgattatc catacagacg aaaaaatcaa
     4981 tagtgatgat gagccagtaa aagcaattcg acgaaaaaag actgcatcaa tggtccttgc
     5041 tgcacaagca gtgaaaaacg gtgaagcaga tgctgtattt tcagcaggga atacaggcgc
     5101 gctactagca gcagggttgt tcatcgtagg acgtatcaaa aatatcgaac gccctggctt
     5161 gatgtctacc ttgccagtag tagggaaaga aggtgccggt ttcgatatgc tggatcttgg
     5221 cgctaacgca gaaaacaaac cagaacattt gttgcaatac ggtattttag gttcttttta
     5281 tgcacgtaaa gtccgaggta tcggacgtcc tcgtgtcgca ctcttaaaca acggaacaga
     5341 agcaacaaaa ggtagtgaag tgacgaaaaa agcctatgaa ctccttcaga atgaaacaag
     5401 cttgaatttt attggaaacg tagaagctcg tgagctactc aatggtgtgg ctgatgtagt
     5461 ggtcacagat ggatttacag gcaacgctgt tttgaaatct attgaaggaa cagcaatgaa
     5521 tatgatgaat ctattaaaat ctgctattct aaatgaaggg atcaaaggaa aaatgggcgc
     5581 tatgctttta aaagacggct tacgttcttt gaaagcagaa atggattatt ccaaacatgg
     5641 cggtgccgtt ttgtttggct tgaaagcacc agtcattaaa actcatggag caacaggccc
     5701 cgatgctgtt cgctatacga tccgccaaat ccacacaatg cttgagacag atgtagttgg
     5761 acaattagtc gaacaatttg aaaaaagcga agaatagtat ttggatatct gaagcaatcc
     5821 gttccattga aaaaaaggtg gacattcctg aaaaatgcca gtaaaattag ccatggtgta
     5881 ggtaattgac aagtgtatga ttcttggagg tgaaaaagtt gactcgcgaa gaagtattta
     5941 acaaagtagc gaaaattatt tcaaatcatt ttgagataga taccgataaa gtgacggatg
     6001 aattgaacat caaagatgat ttaaaagctg attcaattag tattatggaa ttcgttttag
     6061 agcttgaaga tgaattcggt acggaaattt cagatgaaga cgctgaacaa attgaaacag
     6121 tcggtggcgc agtagattat atcagcagcc atcttaaata atttcaaata aaagcaaaga
     6181 aggataaaaa gctgcataca gctttttatc cttctttttt taatcttttt gacacgtaaa
     6241 agtcattttt ctgataattc tggcgataaa cagaaattat gttgcaaagt aaagcgattt
     6301 tctatataat tattaataat tcattacaca aagataagaa taacctttgt tataaaacgc
     6361 tttattctgt gtaatgtcct tttttattaa gaaaaacttc catttaggaa gcagagaggg
     6421 gtattcgatt gtccgataac caattattag aagttcagaa cctacataca ggattccgac
     6481 tcaaagatga ctattacgat gcagtagatg acgtttcatt tactttagac aaaaacgaga
     6541 ttttagcaat cgttggggaa tctgggtgcg ggaaaagtac cttggctact acgattatgg
     6601 gattacttga tcctaataac acaaaaatta caggtgagat tttatataac gatctgaatt
     6661 taatcgacct gaacgaaacg ctctataata aaatccgcgg aaatgatatc ggaatgattt
     6721 tccaagatcc gttgtctgca ttaaatcctc tcatgagaat cgaagaccag atcaaagaag
     6781 gactttccta tcacacaaag atgaatgcag aacagcgtca agctcgtgca ctagaattgc
     6841 tagaacaagt agggattcct aatcctgcga gagttggacg ccaatatccc catgaactat
     6901 caggcggtat gagacaacgt gtcatcatcg caatcgcaat cgcctgcaaa cctccaatcg
     6961 tcattgcaga tgaaccgacg acagccctag atgtaaccat ccaagcacag attcttgatt
     7021 tactgaaaga ccttcaggaa gaaacaaaaa cagggatcat cttgatcact catgacttag
     7081 gagtcgtagc agaaatggct gatcgagtgg cagtgatgta tggcggacag ttcgttgaag
     7141 tagcaggtgt aaaagaactg tttgatcatc ctaagcatcc ttatacacgc tctttactga
     7201 actctatacc acaagaagga aatcatgatg cagaactcca tgtgatcgaa ggtgtcgttc
     7261 cttctctgaa aaacatgcct cgtaaaggtt gtcggtttgc accacgtatt ccatggatac
     7321 cagcaagcga tcatgaagaa gagcctatcc ttcatgaagt cgcaccgaac cacttggtac
     7381 gttgctcctg ctataagcat ttccacttta gagacgaaaa aggagaggtg tagatgacag
     7441 aattaatcac aatcaaagac ctgaaagttc attaccctat tcgcagtgga ttcttcaatc
     7501 gagtaacgga tcatgtatat gctgtagatg gtgtggattt tattatcgaa aaaggaaaga
     7561 catatggttt agtgggagag tctggctctg gaaaatctac tacgggaaaa gccgttgtgg
     7621 gattagaaaa ggtaacagcc ggacaaatca tgtatgaagg aaaagatgta acgaagcgaa
     7681 gcaaccgcaa aaaaatgggt tataacaagg atgtgcagat gatcttccaa gattcaatgt
     7741 ccagtttgaa tcctaaaaag cgagtgttgg atatcattgc tgaacccatc cgaaattttg
     7801 aacggttaag cgatcaagaa gaaaagaaaa aggtaaaagg actgctagat atcgttggga
     7861 tgccggaaga tgcgctatat aaatatcctc atgaattttc aggcggacaa cgtcaacgtc
     7921 taggagtagc ccgtgctgtt gctaccaatc caaaactgat cgtagccgat gaacctgtat
     7981 ctgctctgga tctatctgtt caagcgcaag tattgaattt catgaaacga atccagcaag
     8041 aatacggcct cagctattta ttcatttcac atgatttagg tgtagtaaaa cacatgtgcg
     8101 acaatatcgc aattatgtac aaaggtcgat ttgtagaaat cggtacaaga gaagacattt
     8161 ataatgaccc gcgacatatc tatacgaaac gtctgctttc agctattccg caaatcgatg
     8221 tagaaaatag ggaaagccac aaagaaaatc gacgaagagt agaacaagag tatatccaaa
     8281 accaaaaaga atactatgat gcgactggtc gagtctacga tttgcgtacg atcacaacta
     8341 cacacaaagt ggcgttgaaa gatggaggtg caagctaatg tggaaaacga ttctgcgacg
     8401 tgttttattg atgatcccgc aagttattat tttaagtgtt ctgatcttct tattagccca
     8461 agcgatgccg ggggatccat ttaccggttt gatcaatcca aatcaggatc cggcagtgat
     8521 cgaacagatg cgacaagcag ctggcttgaa tgacccatgg tatgtccagt acttccgttg
     8581 gatcggaaat gctttgcaag gcgattttgg tcaaagtttc ttatacaaac gctctgttgc
     8641 tgacttgatc ggcgaacgga tcatcaacac tttatatcta tcgatcttga cagttgtcct
     8701 tacttatttg attgctgtgc ctctggggat gcttgctggc cggtatcaaa attcaatctt
     8761 ggataagatt gtcgtaatct acaacttctt tagttttgct gttcctttat ttatcttcgg
     8821 cttgatcatg ctatttgttt ttggttatcg tttaggctgg ttcccaacaa gtggatcaca
     8881 aacactaggt ttgcaaggtg gatttatcac tcaatggata gaccgtttga aatatattct
     8941 gttaccatca attacccaag catttttggc gactgccgtc acaatccaat atctgcgaag
     9001 tgaagtaatc gattcgaaat cgctcgattt tgtcagaaca gcccgttcca aaggggtacc
     9061 gacgaataaa gtattcagtc gacatatttt ccgaaatgca gcgttgccga tggcttctca
     9121 aatggggtat gaaatcactt cgttgattgc tggttctgta gttatcgaaa agatttttgg
     9181 ttatccggga gtcggaaaac tatttattga ttccatcggc caacgggact ataccgtgat
     9241 cacatcctta gtattgattt taggaatcgc gacgctagtg gggacattac tttcagatat
     9301 catcatgagt atcgttgacc cgcgtattcg gattcaataa aaccaatcag aaaggagaat
     9361 ggatcgatga gtgaaaaaaa caatacagca gttcaagaaa gtattcctcc tatggggata
     9421 cgaatgattg ctcgagaatt taaaaaagat aaaattgcta ttttttcatt aggtttgcta
     9481 gtggttttat tattagtgat ctttatcggt gcgatgctga ccgatcaaga caaagtgatg
     9541 tatgttagta tcttcgacaa atacgctgca ccaggaacag tttcgacaca aggacaaaag
     9601 ttcattctgg gagcagatga aggcggacgt gatgtattag gacaattgat cataggtgct
     9661 agaaactctg ttacgatcgg atttgcgatc acgatcctta cttcgatcat cggggttgga
     9721 ttagggatca tctctggcta ctacggaggg atcattgaca acatcttgat gcggatcgtt
     9781 gattttatca tgattctacc gatcatgctg atcattatcg tcttcgtatc gattatttcc
     9841 agatacaatg tctggtcctt tatattcatc atgagtgcat tttattgggt agctaaagcc
     9901 cgattattcc gaagcaagac attatctgaa gcaagaagag attatgtcag tgcctcaaaa
     9961 acaatgggaa ccaatgattt taaaatcatg ttccgcgaaa tcatgccgaa tctaagttca
    10021 ttaatcatta ctaatttgac gatgaacttt gcggcaaaca tcggtatcga gacaactttg
    10081 actttcttag gtttcggctt gccggcaaat gtacctagtt taggtacatt gatcggttat
    10141 gcaagtaacg gagaagtctt agtgaatcgg caatggatct ggttacccgc atcaatcctt
    10201 attttagttt tgatgttgag tatcaattat gttggacaag cattcaagcg ttctgcagat
    10261 gcgcgccaac ggttaggcta gtatagaagc gaagggggaa ataggaatga agaaaacgat
    10321 ttttggattt gcagcgctga tgtctgctgt cgttcttgca gcatgcgggg gcggaggtac
    10381 agatacctct ggaaacaact ctggaggcaa cggcaataac aaagaggaat taacttttcc
    10441 aattgcaaca aaaaataatg atgatgcaat cgaagacggc gaattagaag ctgcggtcgc
    10501 aacggacagt cagtttaaag gattgttcca gtgggagttt taccaagatt catatgatgc
    10561 agcttttatg gctccttctc atgaaccgct atttgcaaac gatgacgatt tcagaatcac
    10621 agacgacgga gctgcaacgc ttgatctaga tgaagatacg aaaaaagcga caatcaaagt
    10681 aaaagacaac gtcaaatggt cagatggtga agatgtaacg gcggacgatg tgattttccc
    10741 ttacgaaatc attgggaata aagattacac tggtatccgt tatgacgaca ctttccgtaa
    10801 catcgtaggt atggaagaat atcatgatgg aagtgccgac acaatctccg gaatcaaaaa
    10861 aatagacgac aaaacagttg aaatcgaata taaagaagta aacccaagca tgcttcaatc
    10921 gggtggtggt atctggtcat atgcagcacc aaaacatacg ttagaaggtg tagcaatcaa
    10981 agatatggaa tcaagcgatc aagtacgtaa aaatccagtg acttttggcc cttattacat
    11041 gagtaatatc gttgcaggag aatcagtaga atacttgcca aacgagcact actggaatgg
    11101 tacgcctaaa ttgaaaaaga tcacgatgaa atctgtaccg atggcaagtg caactgaagc
    11161 attgaactct aaattatatg atatgatttt ccaaatgcca acagatactt acgataccta
    11221 taaagaaatt gctggctata caaacttagg ccgtgaacaa acttcttata cttatctagg
    11281 attcaagtta ggtaaatgga atgcagatac aaagagtgtg gaatacaatc cagattcaaa
    11341 aatggctgat aaatcattac gtcaagcaat gggctatgca ttagataata atgcagtagg
    11401 tgaacgtttc tatgcaggtt tgagaagcaa tgcgacttca ttgattcctc cagtattcca
    11461 gtcataccat gatgatgaga tgaaaggatt cacacaagat ctagacaaag cgaaaaaact
    11521 attagatgat gctggctaca aagatgtgga tgacgatggt ttaagagaag acaaagatgg
    11581 aaataaacta acaatcaact ttgcttcgat gtccggtggg gaaacagcgc aaccattggc
    11641 agattactat atccaacaat ggaaagaaat tggtttggat gtccaataca caacaggtcg
    11701 tctgatcgaa ttcaattctt tctatgataa attagaaaac gatgatcctg aaattgatgt
    11761 ttaccaagct gcttggaata caggaactga tccaaatcca agtggactat ggggaccaaa
    11821 tgctgcgttc aactacactc gttatgaatc agaagaaaat acaaaattga tcaacgatat
    11881 cagttcaagc aaagcatttg atgaagagta ccaaaaagaa gcatatcaaa aatggcaaca
    11941 atatgcattt gaagaagcat ttgcgattcc aacgttgttc cgtaatgaag tattgccagt
    12001 caacgaccgt gtcaaagact gggattggtc ttatgatgta ccaaacccat gggcaaatgt
    12061 ttctgttaca gcagattcac gttcataatc actaaaaatg accgaaaaag ggcgatgtcc
    12121 tttttcggtt ttttgatatt tttctgttta tttctctaat attcaggtca aggcgctgat
    12181 ttcatgactt ctccaataaa cggtgttcaa agtccagttt ctcggtatta agtcaaattt
    12241 atgcaaaaat atggaaagcc attttcacaa aattttttct tcatactcga aactaaacga
    12301 atttttcaca acttctcgtc aatcactagg attattaaag ctttacttac cttttgaccg
    12361 aaccatttca aatttgacaa aaaaccagta taataaggaa gtatcgaaaa aatatccata
    12421 aaaggaatgt ggaaaatgga caaccagctg acaaaagaac taaaagaaaa ctataacatc
    12481 gtttttcacg atctaaattt gcttgaacaa gcttttaccc attcatccta tgtgaatgag
    12541 catcgcaatc tgcaattatc ggataatgag cgacttgaat ttttaggaga tgccgtttta
    12601 gaactgatgg tttctcagta tttattccgt ttatatcctc atttgccaga aggaaaattg
    12661 acaaaaacac gagctgcgat cgttcgcgaa gacagcttgt cgaaatttgc caaagaatgt
    12721 cactttgatc aatatgtttt gttgggcaag ggagaagaga attcaggagg acgtacgcga
    12781 ccagcattgc tttgcgacct attcgaagct tttttaggcg cgttatatct tgaccaggga
    12841 ttcgacacga cccatgcatt catcgaaaaa gtgatttttc ctaaagtcaa agcaggtgct
    12901 ttttcacatg agatggatca taaaacaaaa ctacaagaag tcttgcaaaa atcaggtgat
    12961 gtatcaatcg aataccgatt gatcaatgaa gaaggtccag ctcatgaacg agtattttgg
    13021 atcgaagttt atgtagatga tcaattgatt ggcactggac aagggaaatc gaaaaaatta
    13081 gcagaacaag ctgcggcgga aaatgcattg gcagcactgt aaaagtaagt gagggaaagc
    13141 tttgtatttg aaacgaattg aaatagccgg ttttaaatca tttgcagaca agacagtcat
    13201 tgattttgaa aatagcgtca cagcagtggt tggaccaaat ggcagcggaa aaagcaatat
    13261 tacagaggct atccgctggg tattaggaga acaatctgct aaaagtctgc gaggcggaaa
    13321 aatgccggat atcatctttg ccggttccga tacccgtaag cagctgaata ttgcagaagt
    13381 cacagtgatt ttagacaata gtgatcatta tctgccattg gagtacaatg agatcagtgt
    13441 aacccgccgt tatcgacgga ctggggaaag cgagtttttc atcaataaac aaagctgcag
    13501 attaaaagat atccaagaat tgttcttaga ttctggatta ggaaaagaat cgttctcaat
    13561 catttctcaa ggaaaagtag aagcgatttt cagtagtaaa ccggaagacc gtcgtgggat
    13621 ctttgaagaa gcagctggtg tcttgaaata caagcagcgg aaaaagaaag cagaacagaa
    13681 gctttttgaa acagaagaca acctcagccg cgtccaagac atcatccacg aattggaaga
    13741 acagttaact cctttggccg cccagagtga ggcagcaaag gagtttttac ggctaaaaga
    13801 aacactgact caaaccgatg tctctttgat ggttgctgaa atcaagacag caaaaaaaga
    13861 ttgggacaac aaacaagcac agcttgcgaa attcaatcta gaattaggca aactatctga
    13921 gtcgatccaa gaacaagaat ccattttggc gaagcagcgt aaagaaaatg cgcaagccga
    13981 tcgtctgatc gaaaaaaatc agcaagtatt attagatctt tcggaaaaac tgaagcagac
    14041 agaaggacaa aaagatgttt tgcaggagcg gacaaagcat acacaaaaaa gctcgcaaga
    14101 atatcaaact tcattagcag aagcacaaaa aaaggttaaa cattttgaaa agcttcaaga
    14161 aagcttgatg aaagcagcag cagaaaaaga aacagagatc caaaaagctg aagcaaatct
    14221 cataaaaaca cagcaagaat tagaaaaata ccaaaaatca acgaaagaat tattggcaga
    14281 attaagagat caatatgttg atttgatgca agaacaagca gctgtaggaa acgaactgaa
    14341 gtatctagaa cgtcaatata tacaagaaac agcaaaaagc aagcagacgt tagccaagca
    14401 atcggaagta gaagcatcag tagaccgatt gatcttacaa aaagaagaat tgacacaaaa
    14461 gcaggcgcag ctaaaatcat ctttaactga aacaaaagag aagttagaaa tgatccaaca
    14521 aaacgggaaa aagttccaag aagcattagc aaaagaacag cctaaaatgt atcaattaat
    14581 gaatcaagtc cagcagctac gtgctcgtaa gaaaagcctt caagaaatcc aagaaaacta
    14641 ttttggtttt taccaagggg ttcgattggt cttgcagcat aaacagcagc tttcgggtat
    14701 tgtcggagca gtggctgaac tgatcgatgt tcctgcagat ttcacgttag ctatcgaagc
    14761 agctttaggt ggggcagccc agcatgtcat cgttgaaaat gaaaaagatg ctcggcaagc
    14821 catcacgtat ttgaaacagc aaagaggagg aagagcaaca ttccttccac tgacgacaat
    14881 caaaccaaga caattaccgg ctcatatatt gacacaagca gcagctgtag aagggtttat
    14941 agggattgcc agtgaacaag tcagttatcc cgatcaaatc caaactgtgg ttcaaaacct
    15001 gctaggaacg atccttttag ccaaagactt aactagtgcc aatgcaatcg cgcaaacgat
    15061 ccgctatcaa tatcgagtgg tttccttaga aggtgatgtg atgaatgccg gaggatccat
    15121 gacaggtgga gcgaataaac gaggaaacca aggcagtttg tttgtacaaa atcaagaatt
    15181 gaaacagttg actagtgaat ttgaagaagc agataaacaa ctccaagcac aagaaaaaaa
    15241 agttcaggag ctgcaacaag aaacagctcg tttagccgaa gaacaagaag ttttgcgtac
    15301 acgaggcgaa caattacgtt ttgaagaaca agaagcgaca aatcagctac aaaacatcat
    15361 aaatgaactt gaacgttttg aaaaagaaaa gcaaatctca acttttgaga cacgtgaact
    15421 gcagcagttt atcgaagatt acgaaaagca aacgaacgaa ttgaaagaca aacaaacaga
    15481 tcttgaatcg caacgacaaa aaatcgacga agaaatcaaa tcgttaagtc aagaaagcga
    15541 ccagatggaa gccagaagag cacaagtaca aagtcaaaaa gcacaagaac aagcagatct
    15601 tgctgtcttg aaagagcagt ttaatcatct gcagatccag ctccgcggtg cccgagtcca
    15661 aaaagcagag gcaaccgaac gtcaagaagc gatagaaaag cagttggcga cattgacagc
    15721 agacttttct gatcatgaag tcacagaaga aagtttggaa aaacaaatta acgaattatc
    15781 tgctcagcga gaaacattaa aagccgagtt ggcaaaagcc aaagagcagc gagatagaag
    15841 gcaaaaggag atcgataagc ttgaagcagt cttggcagag cgtaatcgtg agcaaaaagc
    15901 acgactgtcg gaacaatcca aattagaagt ccaaaaagac cgagctgaaa tgattttaga
    15961 taatcatttg acctatctgc agtcagaata tcagctgaca tttgagaaag cttcccaaga
    16021 ctatcaagaa acaaccgata tcgaagacag tagaacaaag gtttcatcct taaaagaaca
    16081 gattgaaaaa ctgggaccag taaacttaaa ttcaatcgaa caatacgaac aagtcagtga
    16141 aagacataca ttcttagcaa cacagcgaga tgatctgtta gcagcgaaaa accaattgtt
    16201 tgaaacgatg gatgagatgg atgatgaagt gcggacaaga ttcaaagaag tatttgaagc
    16261 tatccgtcaa gaattcaaaa ttgtctttcc aaatatgttt ggcggcggta aagctgaatt
    16321 agtactgacg gaaccaactg atttgctgaa aacaggtatt gagattgaag tacaacctcc
    16381 tggcaaaaaa ctgcaaagtc taagtttgct ttctggagga gaacgagcac ttacagccat
    16441 cgcgttgctc ttttccatta tccgtgtctg tcctgttccg ttttgtatct tagatgaggt
    16501 agaagcagcg ttagatgaag ccaacgtgaa acgttttggt cgttacttga gcgatttcca
    16561 agatgacaca caatttatcg tagtcacaca ccgcaaagga acgatggtcg cagcagatgt
    16621 actgtacgga gtgacgatgc aggaatccgg tgtatcaaaa atcgtttctg tacggatgga
    16681 agatatcaat gaagaggcga aaatcaacga aacgaaagtg taggaacgaa aatgatcaaa
    16741 ttagtagcaa tcgatttgga cggtacatta ttaaatgaac aaaagctgat ttcagatgag
    16801 aataaacaag cattagcaca agcaaaacag caaggggtca agatcgttct atgtacagga
    16861 cgccccttag ctgcgatggc gcattatctg caagaattag gactggtaga tgaaggtgac
    16921 tacagcatca ctttcaacgg cggtttggta caaaaaaatg atactggtga aatcatggaa
    16981 aagaaagtga tggaagtatc agatatccaa cgcttataca aactggctca gcaattggat
    17041 ctgccactag atgttttgtc tgacaatgtg gttttacagc tgcctagtgc cccaaggaag
    17101 caatccttgt acaatgtgtt gaataagctg ctgcaattcc aaccagcgga tataagcgat
    17161 attacagatg aatttgtgct taataaggca gtaatcgctt atgaccaaga agaattagat
    17221 cctaaaatca aagaaatacc agcagaattc catgaaatgt atgagatcat caaaacaaga
    17281 agtatgcttt tggaatttat gccaaaaggt gttacaaaag cttatggtat ttctttattg
    17341 gcaaaagatc ttggtttgaa acaagaagaa atcatggcga tcggtgatga ggaaaatgat
    17401 ttaccgatga tccaatatgc tggactaggc gtagcgatgg agaatgctgt gcctttcgtc
    17461 aaagaagcag cagatttcgt gacagccagc aatgaagaaa atggcgtagc caaagtgatc
    17521 caaaaatttg tattagagta gggggagtca aatgggattt tttgataaaa tcaagcgtgc
    17581 ttttactggc gaagagaaaa cagaagaagt tgaagtacag gagaagtacg acaagggttt
    17641 agaaaagacg cgtaaaacat ttggtgaacg gatgaatgag ttgtttgcca attttcgaac
    17701 agtcgatgaa gacttttttg aagaattaga agaaacactt atcggtgcag atgtaggttt
    17761 tgaaacagcg atacgaatca ccgaagcatt acgtcaagaa gtgaaactca gaaatgcgaa
    17821 aaaatcggca gaagtccaaa atgcgatcat cgagaaactt gtggatctct atgaagcgga
    17881 aggaatcaat gaagtaaatg aactaaatat ccaagaagac ggactaacag ttattttgtt
    17941 tgtcggtgtt aatggtgtag ggaaaacaac aagtattggt aaacttgccc atcagttcaa
    18001 aaacgaaggt aaaaaagtat tgatggcagc agcagatacc ttccgcgctg gagcaatcga
    18061 ccagttagtt gtctggggcg aacgcgctgg tgttgaagtt gttcgtggca atgcaggagg
    18121 cgatccagca gctgtcgtat tcgatgcttt ggaaagagca aagacagagc aggcagatgt
    18181 tttactagtt gatactgcag gccgactgca aaataaagtg aacttgatga acgaattaga
    18241 aaaaataaaa cgagtaatcc agcgggaatt accagaagca ccccaagaaa cacttcttgt
    18301 attagatgca accactggtc aaaacgcgat ggttcaagca aaacaattca aagaaacaac
    18361 agatgtgacc ggtcttgttt tgacaaaatt agatggtaca gcaaagggcg gtatcgtact
    18421 tgctatccgt aatgaattgc atttaccagt gaaattggtc ggtcttggtg aaggaatcga
    18481 tgacttggag ccgtttgatc caaatgattt tgtcgttgga ttgttcaaag gattactaaa
    18541 agaagaataa cccatgtcta aaaagcagga gctgtgacaa aagttgcagc tccttgtttg
    18601 aatgattgtt tttaacatag ctgtgttttt gatgccttca tttttatact tatttgtaag
    18661 cggttctcaa acaatttcgt tctttttctt agactttttg attataatta gattcatatg
    18721 aattggaggt cacttaatga tgaattttaa gcaattatta ttgcatgtca atgcgcgccc
    18781 ttttatcgac caagctcgat ttggtataga acgggaagga cagcgggttg atcttgcagg
    18841 aaatctagca aaaaccgatc atccagcaat ctttggcgat cgatcctatc acccctatat
    18901 ccaaacagat tttagcgaaa cacaaacaga gatgatcacc cctgttaccg attctattcc
    18961 cgaattattt cagtatctcg ctgctgttta tgatgtgact gctcgttcta taccgaaaga
    19021 agagatgatc tggccattaa gtatgccacc tgccttaccg gaaaaagacg aagagatcat
    19081 tattgcaaaa ttaaaaaatt tcgaagatgt cttgtatcga cgttatttag caaaaaaata
    19141 cgggaagcga aaacagatgg taagcggtat tcatttcaat tttgaatttg gcgatgagtt
    19201 gctaagaaca ttgttcagcc atcaggaaga atttcaagat ttttccgaat tcaaaacaga
    19261 actttatttg aaaacagcga gaaactttat gcgctatcgc tggatgatca cttatttatt
    19321 cggtgcttca ccaatgagtg agaagaacta ctttttagat gaatcacatc cgcaagaacc
    19381 tgttcgcagt attcgcaaca gtgcgctggg ctatacgaat catccaaatg tgaaagtttc
    19441 ctatgcttct atgaaacagt atttagcaga tatcgagcga atgatcgaag aagggaaact
    19501 ttcggaggag aaagaatttt atacaccgct tcgtttccga ggcggaaaga aagtcgcaga
    19561 tttagcaaca acaggtgttc gttatattga attgcggaat atcgatttga atccttatgc
    19621 aagattgggt atcaatccag agcaagttcg gttcttacaa ttattcctga tgtacatgtt
    19681 atggacagaa gaaaaagaag actgtgacca atgggtagca gaaggtacga ctcgaaataa
    19741 caaagtagca ctagaacaac catcagatca aacagaattt catcaagaag gtagagaaat
    19801 tcttgaagga atgaagcaaa tgctggttga attggattgg ttggattctc tttatttagt
    19861 agaggaagca ttgactcaaa tggatcatcc tgaacaaacg ttagcagcga aactctatca
    19921 agaagcacag ctatcgagtc agcaagaagt tgctgtggca ttgggacatc aatattataa
    19981 agaaagccat gaacgtccct atcagttggc cggttttcgc gaaatggaac tttctactca
    20041 gatatttatg ttcgatgcca tccaaaaagg tgtccaagtc aaagtattag atgagtcgga
    20101 tcaatttttg cgtctgcaat tccaagacca tgtagaatat gtgaaaaatg caaacatgac
    20161 aagtaaggac agctatatcg tcccacttat catggaaaac aaaacagtaa cgaaaaaagt
    20221 cttaaaagaa gctgggttcc gggtaccagg aggcgcagaa ttttcatcca tggaagaagc
    20281 ggtaaaagct tatccgagat ttgccgagca ggcatttgtg atcaaaccta aatcaaccaa
    20341 ttacgggtta ggtatcacga ttttcaagga aggagctagt ctggaagatt atcaagcagg
    20401 tttagccatt gcttttcgtg aagacagttc ggttttagta gaagaattta tgccgggaac
    20461 ggaatatcgt ttctttgtga tcgacggaga agtccaagcc atcatgttgc gagtccctgc
    20521 taatgttatt ggtgacagta tccgaacagt gaaagaactt gttgaagaaa aaaatagtga
    20581 ccctttgcgt ggaacgaatc atcgtgcacc tttagaattg atccaattag gtgaattaga
    20641 acaattgatg ttgaaagaac aagggttgac gatcgaatca gttccccaag ccaatcaaat
    20701 tgtttatcta agggagaact caaatatcag tacaggtggt gattcgatcg atatgactga
    20761 tgaattttct gaagcttaca aaaaaatcgc cgtttctgcg gtagaagcac taggagctaa
    20821 gattagtggt atcgatttga ttataccaga taaagaaatc gatcctacaa ctgataaaaa
    20881 agcatatggg atcatcgaag caaatttcaa tccagccatg catatgcatg tttatccttt
    20941 tgcaggaaaa ggcagaagat tgacgatgaa tgtattgaaa ttgttatatc ctgaagtatt
    21001 ttaaaagaaa aagcttttga cagattgtcc tatttgatgt caatctgatc aaaagctttt
    21061 tttgcatgta aaaatttatg tgttttttcg ttttaaaata aacgatccca gaagcttttt
    21121 ttcttttttg gtttttcttt ttcagctggc gaagagtttt cttctgggta ttttttttcg
    21181 atatcaatca caggttcatt tactgcttct tttgctgtta agagcaatcc gaattcctca
    21241 ggatttgcag tgacgtaatc gttgactaca gtgaaacggc tattgttttt cgttgctagc
    21301 tggatatatt ggttttggac agaaaggggt agagccccat tcaagagtat ggaagcatct
    21361 ggatgttttt tgagttcttt taaaaagttt tctttgtttt ttggttggat catttcagca
    21421 acagtcatac taagatagca gcgttccctg aatgtcccta aatatttatg ctgttcttca
    21481 gggttcacta aaggtgtacc ataaagtccc ttatccaaat ggctttttac atcatcttgt
    21541 gccataaaaa ataccctcct tcttctcttt gtctttctta cgattatagc atattcccaa
    21601 taatacctaa aacatatgaa aaagcggttg cttttgttca acgattcact taaaataaga
    21661 atgaaaatca ttctcaatta gaaaggtgga ttggatgcgc tacggacgac tagtagcatt
    21721 attagttatt ttaagtagta tttcattgtt catcggagta tcgaatgtac aattgtcaga
    21781 actgctccag ttagatgggc aaagcttaca aatcttgcta gtgactcgtt tgccacgaac
    21841 gatttgtttg atccttgtgg gagcgaccag tagtatttgt gggttgatca tgcaacattt
    21901 gacccaaaat aaatttgttt caccaacgac tgcgggcacg atggatagtg cgcgtttagg
    21961 tattttagtg gctatgattt tcctacctgg tgcatccttg attgtccgat ccttgacagc
    22021 attttgcttt gcttttgcag gaacattgct ttttttatcc cttacgcgat tgttcctcca
    22081 gaaaaatcaa ttgatgcttc cgttgattgg agtcatgtta gggaatatca ttggttcagt
    22141 tgctactttt tttgcttatc aattccagtt ggtacaaaat atgacttcat ggcttcaagg
    22201 gaattttgcg actgtgatac gaggaaatta tgagttattg tatgctgttg ttccattgtt
    22261 gctcttggtt tggctatttg cttaccgatt tacgatcatt ggtctgggcg aatcgtttgc
    22321 agtaaatctg ggaatagatt accagaagat gcagttttta ggcattggct tagtatcatt
    22381 ggctagtgca gtcatgttga tcatggtagg aagcattcct tttatcggag tgatcattcc
    22441 gaatcttgtc tctagaatat atggagatca agtgcacaaa acaattggcg taactgcttt
    22501 agcaggtagt ttgttcttag tattttgcga tcttgtcgct cgcgtgttga tttttcctta
    22561 tgaaatacca gtcagtgtga tcgttggaat catcggtggg gctatcttcc tttatcttct
    22621 gataagggga cgacgatatg cttaaaaaaa agccatctat ttttattggt atgcttgttc
    22681 ttgttttatt tgttacagga atgtacttga cgatccatac atatggaaac tggcattttg
    22741 catgtgcatt gaggagtaag aaaatttttg catttatcct tgtctcgcta gctgtcagca
    22801 gtgccacaat cagctttcag acaattacgc ataaccagtt tttgactcct tcagtattgg
    22861 gacttgagtc gttatatgtc cttgtccaaa cggtcctttt cttctttatc ggaggagtga
    22921 cgatgcttca gcagacaggt acagtttttt tcttattgaa cgttgggctg atggtcgggc
    22981 tgagtctatt gttatttttc tttcttttga aaaaaatgag agcgaatctt tttttattac
    23041 tgatgtcagg gatgatttta ggtacgcttt ttggtagtgt cagtaccttt ttacaagtca
    23101 tcatggatcc gaatgaatat gatttgcttc aaggcagatt atttgcaagc tttggcaata
    23161 tccagagtca gtatcttttg cctgcttctt tgatcattat cggctgctgg tacctgttat
    23221 ttcgatatcg acatgtgcta gacgttttcc atctcggaaa tgaacaagca gtaaacctcg
    23281 ggatagacac agatcgtttt gaatttttga ttttatgttg tgtcagtctt ttgacaggga
    23341 catcaacggc tcttgtgggt ccagttactt ttttagggtt tattgtcgca aatatcagtt
    23401 atcgtgtctt ttctacttat cgtcatggtc agctatttat cggaagcttt ctggtagcta
    23461 tgctgtttct gacaggagga cagctcgcag tagagcagat tttcggctgg aatacaacag
    23521 tgagtgtcgt cgttgaattt gtcggaggaa tttattttgt cacaaaattg attcgcgaaa
    23581 ggaagagtat cctatgattg atttacaaaa ggtcaataaa ctgtaccatg gaaaatcagt
    23641 ggttaaagat gtacagttaa cgattcctga aaagaagttg actgctttta tcggtccaaa
    23701 tggtgctgga aagtcaacgg tgttgtcgat gatcagtcgt ttgataccaa aagatacagg
    23761 tgaaatctat ttagaccata acgaagtaaa ggcttggaaa tccaatgaat tagccaaaaa
    23821 attatcgatc ctacgacaat cgaatgaaat aaatgtccaa atcaccgtga aagaattagt
    23881 agaatttgga cgatttcctt atacgaaagg aaaattgacg acaaaagacg aggaaatcgt
    23941 tcaggaatca ctggaacacc ttgggttaga agaaatagcg gatcaatcga ttgacactct
    24001 ttcaggcggt caactccaac gtgcgtatat tgcaatggtg ctagcgcaag acacggatta
    24061 tattttactg gatgaacctt tgaacaatct agatatgaat tttgcggttc aaatcatgca
    24121 gattttaaaa aatttagtac aagaaatcgg gaaaacaatt gttattgttc ttcatgatat
    24181 caactttgct gcaagttatg cagacgaaat tgttgcaatg aaagatggac agttatttac
    24241 gcaaggaacg acccaagaaa tgataaaaaa agatgtattg gatgaattat acgaaatgga
    24301 catacggatt tgtgagattg aaggccgcag attctgtctt tatttctaaa actaacatta
    24361 ggagagaaga gatgaaaaaa ttagtagtag gtatcttgat tctagcatca tttggtttag
    24421 cagcatgtgg aaatagcaac aacaccagtc aggcagacac aaaaaaaagc agcacacaaa
    24481 ctgaaactac attgacgata acagatagta atggagacca aatcgaggtg ccaaataatc
    24541 cagaaaaagt cgtcgtattc gacaatggtt ctttagatac gatggatgct cttggtgttg
    24601 gagataaggt agttggagca gctacaagca gccttcctga gtatctttca tcctataaaa
    24661 aagtagaatc agcaggtgga ataaaagaac cagacttaga aaaaattaat cagcttcagc
    24721 cagatctaat catcatttct ggccgacaaa gagattttca aaaagatcta agtcaaattg
    24781 ctccgaccat tttcctttct ttagatgcga aaaatccatg ggaatctttc cagcaaaatg
    24841 tcactgcttt aggggagatc tttggtaagc aagaagaagc taaaactcaa ttagaggaat
    24901 tatctagtgc aatcgatcag acgaaaaaga aagcagaagc tactgacaaa aaagcactag
    24961 tcacacttgt gaatgaaggg caattatcag cctacggatc tggttctaga ttcggtttca
    25021 tccatgattt atttggcttt gaacaagcag atgatcaaat cgaagcatcc actcacggtc
    25081 aaagtgtttc ttatgaatat gtgctggaaa aaaatccgga tatcttattt gtagtagaca
    25141 gaacaaaagc tattggtgga gacgacagca aagatgatat ttctgccaat gaactggtag
    25201 cacaaacgaa tgctggtaaa aatcagcaga tcatctccct tgaaccagat gtctggtatt
    25261 taagcggggg cggtttagaa tcaatgaaac tgatgatcga agatgtgaat caagcattta
    25321 aatagcataa ataacagagg attaaactct catactatgt aacaataatg tttcttacat
    25381 tcttaaatag caagagccta tcctcaaaga agttatcaaa aaccatccgt aaaatcgtat
    25441 tgatgatttt acggatggtt tttatttatt tgagaaatct tttttcaacg tgaattcatt
    25501 atctacatca tacgggttga ttctagaatg gggagtggca aaaaatagtg tgatccattt
    25561 tttcagcatc aagatcgcct cctttgattt gaatcaaagg tacaaagcga aacttagata
    25621 aaacttaaat ttagatattt ttattttgta ccgatctctt ctttaaacga tgttccatct
    25681 gctgcttctc ggcaataagt ccactagact agaaaatatg agaagctatt ttctgtccag
    25741 cgttcttatt actcaaaaca aatcgcagtt gtcacaatct cttctaaacg atgttccatc
    25801 tgctgcttct cggcaataag cccactagac tagaaaatat gagaagctat tttctgtcca
    25861 gcgttcttat tactcaaagc aaatcgcagt tgtcacaatc tcttctaaac aatgttcaat
    25921 cagctgacct tcggtattag ctcaaagcac tgatttcaca acctctattt aggcatgtgt
    25981 ctcagcaagc ggttgatagt tgatgatctg catttttcga taaaaatcgg cgggaagctt
    26041 actccaccgt tttagtaatt gatagaaata actctcttct gctttgattt tatactcgct
    26101 taatatcaat ccaaaactat tcgttttttt tgaagctaat tttttataaa tatccaatgc
    26161 tttggtttta tcttcattga caaagagtgt ttttacttca atataagaac cctcgatatt
    26221 ttgtgtttct tcgataaaat agatgttttt tatatattcc ttcatagtga ttcctccaaa
    26281 gaagtctttt atttgataag tttactctac cgaagagttg ttaataatcc gtgaacaaaa
    26341 agtaattctt tttccaatag ttgttaaagg ttttttattt tttatagtat tttttgttat
    26401 ttaagaaagg aataaggtta aacaaataac aggttgcttt ttgggtcttt ttccgttcaa
    26461 gaaactgaac gaagaaaagg gaaagttgtc tcttttgtga taagagaaat cataataaac
    26521 gaatgactta ctttccaata aattgagaac agtcagaacc agacaaatta gttgcatctg
    26581 atgaataaag tgattattct atgacatgag gtgatacaga tgaaattaga agtgacaaaa
    26641 gaagcacaag aagtattgaa gaataaatta gaagcagacg atcaactttt attagatatc
    26701 gaaaacggtg acggtccatt tgcagaaagc caagtcagtt gccaattgga tacggcattt
    26761 cgattgatca ttgtcaaaaa agatacacaa acagatctaa gtctttattc tgtagtggct
    26821 gatacaccag ttggaccaat caaaatcaaa gacagtgcaa tactttacat ggatgatcca
    26881 tccacacttg ctttagaacc aacttataat agtttacaat taaaaggacc aagcggcttg
    26941 agaaaaggca acttgcaagt tgttcgaaaa gactagaggg ataaaatggg aaaattggcg
    27001 atcatcagcg acctacatgt ggacatcaat aaattcggcg aatcagagct gatgcagctt
    27061 tggcaagttt tgcaaaagca caagatcact cggcttcatc tagccggaga tacggctaat
    27121 aaagtagacc gttgcctagc tgttgtcgaa tttttcgtca ataaaggatt atctacgaca
    27181 tttcatttcg gcaatcacga gttggcagat gtgcccaatg aacagatgat ggaccatttt
    27241 ccagacccac attttttaaa tgaacggtat attgctttaa atgagcagac cgttctttta
    27301 gggatgaatg gctggtacga ctatcagttt tccgaattga aagattacga ggcaatcgta
    27361 cgaatgaagc gtttgtattg gtatgatcgg ttcatccagc gtgggaaaac agatctcgag
    27421 gtcaatgcag aaatgcttgc agctgcaaaa aatttgctag accagctgga agcaaaaaaa
    27481 cttgaggtga ttttatccac tcatttcgtt cctaaacggg catttatcat gtatcaatct
    27541 gctccttatg agcgttggaa caaattaaat gcatttttag gatcagaatc attcggagaa
    27601 ttacttgacc gttattcaaa tatcaaacaa gtagtttttg gccatacgca tcgtcgcttt
    27661 gaagataaat ccatcggtca cacgatttac agctgcagac cttttggtta ttattatgaa
    27721 tggcagctga cccgagattt tgtcttgaaa gaacagttgc tagacagcta tgatcctatg
    27781 aaattacgtg tcctcttgcg tgcccatcac ccagcttttc aggcctatca aacacaacat
    27841 ttgcaagagg aatttgaaca agcgatgaca atcgttccgt attgagacag cattagtaat
    27901 gtgtaaaaga aaataccttg taaaacataa ggataagtaa gagcagtaga tccatttatc
    27961 gtggatatgc tgcttttttt gcggaaaata atcagcgaat gtttatttga tcggatgatt
    28021 tgtaactcgc agagtactag atgcaagcgt gtattctttt tttgaacgat aatcacaaaa
    28081 aaaaatataa tatacatttt ttatttaatt ataattaata ttgattgaag tctaggcagt
    28141 caagtcacat tttgatagat aggaggggga cttacgaatt attttaaagg ctatgacagc
    28201 tgtatttcta gattgtgttt gcatcaagtt gcaataaaaa ctagaaatca aatcgggctg
    28261 ataatcattt ataactaatc gatacatagg accaaatata ggtctatgtt cttttatttc
    28321 ataagtatcg taaaacagaa ttttgctatg gattaatcca atcgactgat atgtttagta
    28381 aataaagaaa gaggaatgtc aatgatgaaa aaagaaatcg tattaacagc agcaatgatg
    28441 ttattcagca tggtagcaag tacgactttt gtttctgcaa ctgaagtata cccaaaggaa
    28501 tataacacag aaggaacgat tacatttgaa gcaggagatg agggtgtaac tcctcctgtt
    28561 gatccagaga atcctgatcc caataaacct gtcgatccat cagatcctcc aagccctgga
    28621 acaggagggg cattatcgat tgattatgga tcaaaattca aatttgggac tcaaaaaatt
    28681 tctactgcgg ataaaacgta ttatgcagct gctgatgtga tgaacgatgg gtctagaaaa
    28741 ccgacatatg tccaagtgac agataggaga agtaccttat ctgggtggaa attaagtgtc
    28801 tctcaaccag aacagtttaa aactgccagt ggggatgaac tagttggagc acagctgaaa
    28861 tttacgaaag ggcaggctgt ttctttggtt gatccaacat atacgccgca aacggtgaat
    28921 tctgaattaa cgttgacacc gggaggaaac aatacgttag caattaatgc taaatcagga
    28981 acaggtgtgg ggacttgggt ctatcgattt ggtgcaaatg aaaatgaaaa tcaagatgcg
    29041 gtacagcttt cggtacccgg taaatctgtc aagttagcgc aacaatattc cactaaatta
    29101 gtttggacat tagaagatac acctaacaac tagtttactg aaaagaactg ttaaaaataa
    29161 atacgtagtc atattgtctt gcgaggtaat cgagcaaaaa ttgtcaaagg ctaggctaaa
    29221 tttgtttgga tacgaatagt tcatctagga atttaacgat caggaggaaa agatatattg
    29281 aaaaagagga ggatcgtgct cattttaagc agtctcttag tgactaatat ctttccgatc
    29341 atagggtact ctttggaatt gaatcagttg gagcatggaa atagaagaga cgaagaaagc
    29401 aaactcactt cgacattcga cagtttaata gaatccaacc agacacaaga aagcagtgag
    29461 gatttaagta tttcgagtag tggagagacc actgacaacg tagaagctga gggttcggac
    29521 aaacaaggac tagaagatgc accaatttct gcggttgagc tgcctgacga tcccaatatt
    29581 atttctatcg ataaaatttt tcaaacacct atcggtacta gcacgtccat attggaaaat
    29641 gggaagttac tgcagttgaa cccagcagaa aggtctcaaa gaggagctat ttggtcaaat
    29701 aagaagatta gtttactctc ggattttaca tttaaatctt atttatactt aggaaatcaa
    29761 cgagatagag cgggagatgg catgaccttt acattgactg gcgatcctag aatggctagt
    29821 aatcccagtc aagttattgg atcgccaggt atgggaattg gctcatattc tactcgttct
    29881 ggccaacctt acattgcgaa tgcgctctcg attgagtttg atacgtataa aaatagtggt
    29941 tcttctgatc gaatggatcg agagataact gctgataata gagggcatgg acatgtcgct
    30001 tttgtcacgc ctaaaccaaa taataataat tattctggag agcatactgg cgtgacggta
    30061 gctcctacat ttctttctaa tggcacatgg cgcttgttaa taattaaatg ggacgcggag
    30121 caaagaagtc ttacttatga tttggaaggt gtcggtcgct cttctcggat tatacctgat
    30181 ctcattaggc agtttggttc tacagaagta aattgggggt ttacttcttc aacaggtact
    30241 ttttttcaag aaaatgctgt cgctgtcacg cgacttccat cgaatgtcac atcaacagct
    30301 gatgtaaaag tcaacgatag tgattatggg gccatcgctg aagctggagg aaacgataag
    30361 ataactatca gaaatacatt gaaggtcgag ggggattttc ttgaatataa gaaaatgcag
    30421 actagtatcg acctcccaca agaattaact attcccgagc atatcttgat caatggaaat
    30481 caaattgatg ccaaagatat cttgataacc ggaaatcgag tcacgctaaa tctgacagat
    30541 tattttattg ctggagatac gttaataatc gaattggaga caactttgca ggaagtaatt
    30601 cctgaaaaag tactcactat gcattttgaa taccttgaaa acgggaattt gattgagcaa
    30661 tcgaatgaaa taaacctaaa gatcgcaaag ctgaaggaga tagatatcca tgtttattat
    30721 aaagataaag acagtcagat tgatattgct gaaatgaaaa caatcactgg gaaaatagga
    30781 gagaagtata aagaaactcc tattgatatt gaagggtatg tttttgactc ggattcagcg
    30841 aatacagaag gcatcttctc cgaaaataca gaggatatct atttttatta cagaaaaggc
    30901 aaactttatc tctcaactgc tcctcaatat gtcaattttg gaaaacataa aatatccagt
    30961 agaccattaa gtgaattcgg acagttttca ggtgggttga aaattataga tgaacgggct
    31021 tttggaagtt ggaaattaca attgaaacaa gagaaagttc ttacaaatgg agattttgag
    31081 cttccagaag ctctttcctt tgttacctct gaaaatacaa cggttatagg gacatccgct
    31141 gttacgattt tcgaaagtga tcaaaagggt gaaagcgatt tgtcctctct tttagattct
    31201 acagctcatc gtggaatcag aataaatatt cctgtagaaa accaaagaat cggaaccttt
    31261 gaggggaaac tatcttggat acttgcagat gtcccaggaa attaacagga agagaagaat
    31321 ataacaaaat tattgagttt caagaagggc acaggtacca taggctcttg tgtcccacag
    31381 agacaagatt ttgttatagt cttctcttac atatgattaa aggagcgatt ttcttgagac
    31441 caaaacaaca attatttata acactcctag ttattttagg ggcacttttt aacaatatat
    31501 cagtgtcagc tagtgcattt aatttttcag tgacgccgat aacttcagag aatcaaatcg
    31561 acaagagaaa aacttacttc gatcttcaac ttgatccgga tcaggaagta gaagtaaaag
    31621 cggaattgag aaatgataca gaaaaagaag tgaaaatcga tatttctgtg aatagcgcaa
    31681 ccaccaattc aaatgtgatg gttgaatacg gaaaaaacga gattgaaaaa gacatgagcc
    31741 tgatctttga tctggtagat tatgtgagct atccacagat agtgacgcta aaacctaaaa
    31801 gtgtccaaac cgttgctttt catgtcagga tgccgaatga gcgatttgat ggtgtattgg
    31861 ctggtgggat cacattccaa gaaatccaga cggaaaagga ccaaacagaa actaaggatc
    31921 aaagcttatc gattgagaat gaatacacct atattattgc tttgttgatg caacagacac
    31981 tgaacgaagt tgctccgaac cttactcttc atgaagttaa accagatcaa atcaatgcaa
    32041 gaaatgtcat cttagcaaac gttcaaaatg atcaaaaaac ctatatcaat caagtagtta
    32101 ttgaaacaaa aattacaaaa aaaggacatt ctgaagtttt atatcaagag gaaaaagaag
    32161 gattgcagat tgcgccgaat acaaattttt cttttccaac tgctttaaat ggtcaaccgc
    32221 taaccccagg tgaatatcac cttacaatga ctgttttagg aaatgaaaat gaaaatggaa
    32281 aattttcgag aaaaaaagga aatactacga tcaactatac caatcaatgg gtatttgaaa
    32341 aagattttac aatagacgga aaagtagcca aggaattgaa cacgacggat gttacgatta
    32401 aaaaagacaa taattggatt tatatcttag tagcttcact tttcttattg tttattttat
    32461 tatgcatact tttgtttgtt ttgagaaaaa aagaagagaa agaaaagtaa ggttaagata
    32521 acaaatagta aatttttatt attgtaggat ggttgggctc tttttataac aatataaaat
    32581 ataccatttt attaataaaa atgcatacta gtaaatgata taattctaat aacaggtttg
    32641 atcgcgagaa aggccaaata aaacgctctc caaaatgtta aaaaaaagac aggacgatgt
    32701 atattataca aacaagaatc gctgacaaca gtgactcgga tccaggaaat cagttttatc
    32761 cccagctagt tggtgaatgc atggaaagta atatacgtag aaagagctga tgactaatga
    32821 attatgagtt ttttttaagc aaagaagatc acagaagtta ttcattactt aaatatttag
    32881 aagcaagctc aaatttatca gagtcaatat cgaatgttca agaagagttg tcgctatcga
    32941 catttctctt gaaaaaaacg atcgataagc tgaaacatga tttacaaaag ttcgatctag
    33001 agaaaaattt gcgagtaacc gtcagtgaat tggatatatg tctggaaatt aatggaaaat
    33061 gttctagcaa agctctgtta tctcgttata taacggattc tttatctatg aaaatggtat
    33121 tggctttctt tcaggaaaaa tatatctcag tagaaaattt tgctaaacag catcacgtga
    33181 gttattctgt ggcttataaa gtattacaaa gactaaaaag aaatctaaaa aaatatcaaa
    33241 ttttttttga aaagagaaag tt
//
LOCUS       DACGEU010000023        31897 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.023, whole genome shotgun sequence.
ACCESSION   DACGEU010000023 DACGEU010000000
VERSION     DACGEU010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 31897)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31897)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31897
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.023"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(27..602)
                     /locus_tag="IXR40_001004"
     CDS             complement(27..602)
                     /locus_tag="IXR40_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAQ4360870.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQAGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
     gene            complement(607..1581)
                     /locus_tag="IXR40_001005"
     CDS             complement(607..1581)
                     /locus_tag="IXR40_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine nucleosidase"
                     /protein_id="HAQ4360871.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPADIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGMDGLGETNFPMILRKQAEPL
                     HAVDFLADYFKEKTNTSVIALGPLTNIASALKVNPNIGKHMERFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFENLKQTIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIEEAICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFFRKFLTVLLNAQEETIMKDLERLKMG"
     regulatory      complement(1605..1649)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            1864..2832
                     /locus_tag="IXR40_001006"
     CDS             1864..2832
                     /locus_tag="IXR40_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAQ4360872.1"
                     /translation="MVIFYFILILIIIGISYHFLSYFYAKKLVRAGVQRGYDWYEDTG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGTPKTIKSYDGLKLAGQMFIHPNKQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLVPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPNASIILHGGSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMVMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMN"
     gene            2929..3222
                     /locus_tag="IXR40_001007"
     CDS             2929..3222
                     /locus_tag="IXR40_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HAQ4360873.1"
                     /translation="MRSAAYGNQRRKNRLALFNDEQQEIGEMTWSDAGPDIMIVDHTF
                     VDPAYRGQKLAEKLVYTGVELARRDGKKIIPLCPYAKKEFEKKPEYQDVLRQS"
     gene            3340..3576
                     /gene="secG"
                     /locus_tag="IXR40_001008"
     CDS             3340..3576
                     /gene="secG"
                     /locus_tag="IXR40_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HAQ4360874.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAIWMILLFVLAYLSSK"
     gene            3688..4434
                     /locus_tag="IXR40_001009"
     CDS             3688..4434
                     /locus_tag="IXR40_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAQ4360875.1"
                     /translation="MRQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKADYTV
                     YAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFAVRA
                     LEEESVIGGGFFCSPLSPVKTNVPENFEKYVRQVLKTAGKSEKEINEKAVAYRSLAEQ
                     QLMDIQDQAAIVESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQWYPE
                     SGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            4437..6794
                     /gene="rnr"
                     /locus_tag="IXR40_001010"
     CDS             4437..6794
                     /gene="rnr"
                     /locus_tag="IXR40_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HAQ4360876.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILIEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSEEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDITGRRDLRNQLIVTIDGEDA
                     KDLDDAVTVKKLDNGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHDIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILETMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKTRNGKSGKRE
                     GKQAGKRPERNGKKNKRYSDSKQTFGKKKGKKPFYKGVKKKKKKK"
     gene            6816..7280
                     /gene="smpB"
                     /locus_tag="IXR40_001011"
     CDS             6816..7280
                     /gene="smpB"
                     /locus_tag="IXR40_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HAQ4360877.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIIRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            7582..8301
                     /gene="atpB"
                     /locus_tag="IXR40_001012"
     CDS             7582..8301
                     /gene="atpB"
                     /locus_tag="IXR40_001012"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HAQ4360878.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMMTSLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            8354..8569
                     /gene="atpE"
                     /locus_tag="IXR40_001013"
     CDS             8354..8569
                     /gene="atpE"
                     /locus_tag="IXR40_001013"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HAQ4360879.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVIALILVFAV"
     gene            8660..9184
                     /gene="atpF"
                     /locus_tag="IXR40_001014"
     CDS             8660..9184
                     /gene="atpF"
                     /locus_tag="IXR40_001014"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HAQ4360880.1"
                     /translation="MLNQLAIAEVGNAMLGNIIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            9171..9713
                     /locus_tag="IXR40_001015"
     CDS             9171..9713
                     /locus_tag="IXR40_001015"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HAQ4360881.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYEYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMDYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLEKMRNQLNR"
     gene            9736..11292
                     /locus_tag="IXR40_001016"
     CDS             9736..11292
                     /locus_tag="IXR40_001016"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HAQ4360882.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEEALNSAIQEYKDMFLATKGSNSST
                     EDKLKSIQNA"
     gene            11306..12208
                     /locus_tag="IXR40_001017"
     CDS             11306..12208
                     /locus_tag="IXR40_001017"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HAQ4360883.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMFQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            12231..13637
                     /gene="atpD"
                     /locus_tag="IXR40_001018"
     CDS             12231..13637
                     /gene="atpD"
                     /locus_tag="IXR40_001018"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HAQ4360884.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            13651..14073
                     /locus_tag="IXR40_001019"
     CDS             13651..14073
                     /locus_tag="IXR40_001019"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HAQ4360885.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
     gene            14542..14772
                     /locus_tag="IXR40_001020"
     CDS             14542..14772
                     /locus_tag="IXR40_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HAQ4360886.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            14869..16170
                     /gene="murA"
                     /locus_tag="IXR40_001021"
     CDS             14869..16170
                     /gene="murA"
                     /locus_tag="IXR40_001021"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HAQ4360887.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNRPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            16183..16359
                     /locus_tag="IXR40_001022"
     CDS             16183..16359
                     /locus_tag="IXR40_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HAQ4360888.1"
                     /translation="MSNQRYILLTLIKILVVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            16494..16790
                     /gene="yidD"
                     /locus_tag="IXR40_001023"
     CDS             16494..16790
                     /gene="yidD"
                     /locus_tag="IXR40_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HAQ4360889.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFRLTRNKKDKKEPDYKKVVKNTGSTER"
     gene            16854..17321
                     /locus_tag="IXR40_001024"
     CDS             16854..17321
                     /locus_tag="IXR40_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4360890.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVTPTYQGKGIGGKLLETAFQKLSQLASNQTRIIIRTGTTS
                     SAALHLYQKMGYVEIGRVKDYFIHHYSEPIFENGDQLRDQVILAIHLPKNSFN"
     gene            17406..18290
                     /locus_tag="IXR40_001025"
     CDS             17406..18290
                     /locus_tag="IXR40_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAQ4360891.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKTQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLD
                     GDKTFSKLGTAVQMAWRYCERKGLDKNAYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLIGAAANYLAVRQGEN"
     gene            18407..18640
                     /locus_tag="IXR40_001026"
     CDS             18407..18640
                     /locus_tag="IXR40_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HAQ4360892.1"
                     /translation="MSKKNKDIEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYGP
                     KEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            18728..18808
                     /locus_tag="IXR40_001027"
     tRNA            18728..18808
                     /locus_tag="IXR40_001027"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:18762..18764,aa:Tyr,seq:gta)
     gene            18815..18886
                     /locus_tag="IXR40_001028"
     tRNA            18815..18886
                     /locus_tag="IXR40_001028"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:18847..18849,aa:Gln,seq:ttg)
     gene            19402..20109
                     /locus_tag="IXR40_001029"
     CDS             19402..20109
                     /locus_tag="IXR40_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAQ4360893.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRRDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(20168..20812)
                     /locus_tag="IXR40_001030"
     CDS             complement(20168..20812)
                     /locus_tag="IXR40_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HAQ4360894.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDQAKNFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGVPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSANHFKESIIELLNGQVQFEEGSVSYHEQLITDHI"
     gene            20939..21226
                     /locus_tag="IXR40_001031"
     CDS             20939..21226
                     /locus_tag="IXR40_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360895.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            21334..21654
                     /locus_tag="IXR40_001032"
     CDS             21334..21654
                     /locus_tag="IXR40_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAQ4360896.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIA
                     LIGE"
     gene            21972..23048
                     /locus_tag="IXR40_001033"
     CDS             21972..23048
                     /locus_tag="IXR40_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HAQ4360897.1"
                     /translation="MFDQPEAKPREVVFFWTGQLTEKQTEIAKRILCHSEKRHHLIWA
                     VTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNELFLRYRYVFPEEKITLLHGNTA
                     TAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYNGDAGLAHAVQTAIRSNGRFIY
                     LSATPDEKLLKEIKQTFELHKLALRFHRRLLPEPVLVFMNNWRQKCGNKKKINSLVRI
                     IQQLIKENRILLFCPSITMMHRLKITLQEAFPEYEITDVSSQDDQRAKKVQKMREAIY
                     EILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQIAGRADRKGPYTNSRVYFFYE
                     EKTSAIRKACQEIKEMNEEGKQML"
     gene            23045..23764
                     /locus_tag="IXR40_001034"
     CDS             23045..23764
                     /locus_tag="IXR40_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HAQ4360898.1"
                     /translation="MRCSCCGKDIIQNLTFSEIIGVSKSRLPQTCSVCRAQFHLLEAK
                     GCAGCQKPIHLKYEETKKKANTSFVYCNDCQEWKKKYPAYDFQHRAFFTYDEKMQAWI
                     NRYKFMGDIRLAGTFAYKWTQIKKDYPAYIYCPIPLSEKRWLERGFNQVSEMLKAAKI
                     PFQMLLKREQHLLAQAKNTRKERLEMPQPFELAVPLSKIQHKKILIIDDVYTTGQTLF
                     HAADCLQNAQPKIIRTISLAR"
     gene            23892..24443
                     /gene="raiA"
                     /locus_tag="IXR40_001035"
     CDS             23892..24443
                     /gene="raiA"
                     /locus_tag="IXR40_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HAQ4360899.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTADAAALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
     gene            24665..27199
                     /gene="secA"
                     /locus_tag="IXR40_001036"
     CDS             24665..27199
                     /gene="secA"
                     /locus_tag="IXR40_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HAQ4360900.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKAFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTAQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
     gene            27325..28426
                     /gene="prfB"
                     /locus_tag="IXR40_001037"
     CDS             join(27325..27387,27389..28426)
                     /gene="prfB"
                     /locus_tag="IXR40_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078989099.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HAQ4360901.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRGLFDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            28531..29217
                     /gene="ftsE"
                     /locus_tag="IXR40_001038"
     CDS             28531..29217
                     /gene="ftsE"
                     /locus_tag="IXR40_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HAQ4360902.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            29201..30094
                     /locus_tag="IXR40_001039"
     CDS             29201..30094
                     /locus_tag="IXR40_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4360903.1"
                     /translation="MDTMIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFM
                     AVIMNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELK
                     KIQNEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEEAADLKNVSRSDYGGASSD
                     RIFQIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRW
                     PFFLEGGWIGLIGAILPILIITFGYAWFFQLINPSLLRSHYSLIHPQNIVWKINLLMV
                     GIGVIIGSLGSIISMRRFLKF"
     gene            30246..31694
                     /gene="cls"
                     /locus_tag="IXR40_001040"
     CDS             30246..31694
                     /gene="cls"
                     /locus_tag="IXR40_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HAQ4360904.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWLLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDALGE
                     EVRDALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEVAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGEIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYTLQNRFLM
                     DWNSQHTKEVGYSPKFFPSIHTTGDIAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLVYDERMASRVRKAFFEDS
                     KISTHLTKEMYENRGIIIKMKEGLARLISPLL"
BASE COUNT        10607 a         5565 c         6908 g         8817 t
ORIGIN      
        1 tattttgcta atccagctct gtttattcag cctatttttc tttttgaata tatcaagcgt
       61 tgtggcaaca tagtgatgac taatgaaaca acgacgatag acaacaaacg atcaaggtag
      121 tctgtacctg cctgtaccaa gatcacactt gttgtctgac ttaaacctaa cccatgtaat
      181 agctgaacga tcatactgga tcctgaggag gtgatcccgc caaataactg aacggtaatg
      241 atcgaagaaa cgatcgttcc aggtaccgac aaaatcaaag cgagtaataa cagtttcaag
      301 ctgtttttat ctttgccgag atatcttggc aaaatcaatc cagcaagcaa gcctgtgaga
      361 atttggattg gcgaataata cagagaaaaa atatctgtag tcactccact taaaataccg
      421 ctggacaatc ctgtcagcat tccaggtaca ggcccaagca atgcaccagc aaaaatcgtt
      481 ccgatagaat cgagatagat tggcaaacga agccataaag caatcgttcc tccaatataa
      541 ttgatcccaa tacacaaagc catcactgta agtacgcgag ttgccatttt gtttttattc
      601 attttgttag cccatcttta acctttccaa atctttcata atcgtttctt cttgtgcatt
      661 taaaagaacg gttaaaaact ttcggaaaaa aagacgagta tctacttttg tcataatttt
      721 actgttagca ggtttctgcc aaaattcata acgatcaacc aatgtttgtc cacgacttat
      781 tccttgagtt tccacagcag tgaagctttt gaaaccttca cagatggcct cctcgataaa
      841 ataagcaaca gctaacggat cattgatgac acatcctaaa attctttctt gtttccagtg
      901 gaagtcaaaa taaaaacgag tgatcgcttt tagatactct ccctcttcag gattcatttg
      961 acagcagtat tcgaggatag tcggtgtcaa gacgatttct cttgtcacat ctaacccaac
     1021 catttctatc gtttgtttga gattctcgaa tacataagaa gctgcttcag gatcacacca
     1081 gtaattgtat tcagcaactg gcgaacagtt accatggctt ttgtaagttc cacccatcga
     1141 gacaaaacgt tccatatgtt tcccaatatt tgggttgact ttcaaagcag aagcgatatt
     1201 ggtcaaagga cccaaagcaa tgactgatgt atttgtcttt tctttgaaat aatcagccaa
     1261 aaaatcaacg gcatggagag gttctgcctg ttttctcaag atcatcggga aatttgtttc
     1321 ccctaaacca tccataccat gagtgtcttg tgcactgatg aaaggttgct tcaaaggttt
     1381 ttccattcct tgataaacag gaatgtctaa acgatcacag cgttccaggc atttcagcac
     1441 attctgcgta cctatatctg cagggacatt cccacaaact acggtaatag caactacttc
     1501 gatatcaggg gatttgacag ctaatgataa agctaaagtg tcgtcgatcc ctggatcgca
     1561 atcaataatt acttttcgca ttatttccaa tctcctttct ttagagatac ttagtttttt
     1621 attctgggaa gtttccgaac cagtccaaga cgagcgtctt gattataatg cacgaaatta
     1681 gtatactggc ttttattgcg aatgtaaatg ctctcttaca agtaaatcta ttgaggagaa
     1741 ctttaagtaa atgatacaat gaaaaagaaa tggaatttac gtgtgccgaa aataaagaat
     1801 cctatggatc ggtacattgg ataatagata gattatagtt tggcagaaag cggcgggtgt
     1861 acaatggtta ttttttattt cattcttatt ctgataatta tagggatcag ttaccatttt
     1921 ctttcttatt tttatgcaaa gaaattagta agagcgggag tacagagagg atatgactgg
     1981 tatgaagaca ctggtcatcg tttgatggac cctgctgcag tcacgtcagt agaaaaaaaa
     2041 cgacaaaaat tagaagaaga gtgtgaaagc ttttgggagc agggaacacc caaaacaatc
     2101 aaaagttatg acgggttgaa actagctggt cagatgttca tccatccaaa taagcagaat
     2161 aaatgggtca tttgcgtaca tgattaccga agcacaggga aaagagacat gtctcatata
     2221 ggtaaaagat atgcagagaa aggattcaac gttcttgtac ctgatttacg tgcgcacgga
     2281 gaaagtgaag gagaaatcat cggaatggga tggctagatc ggctagattt aattgcctgg
     2341 atccaactca tcttagatga acagccgaat gcgtccatta ttttacacgg cggatcaatg
     2401 ggagcttcta cgatcatgat ggcaagtggt gaaaaacttc catcagcggt caaaggattt
     2461 attttagaca gcggatatgt ttctgtttat gcagaattcc gatatatgtt aagtaaaatc
     2521 actgtctttc ctaaaaaaat ggtcatgaga tatgcgaatc attatgccca gaaatacgcc
     2581 ggttactcct taaagcaagc atcagctacg agacagcttg gcagcaatca tctgccttta
     2641 ttagtcatcc atggtgaaag agatcatttt gtccctacag aagcagcgta cacgattcaa
     2701 aatgctacgg caggggataa agcactgctg cttgttccgg aagcagaaca cttggaagca
     2761 tcgatgaaag atccgaaaac ctattggaca gtgatttttt catttattga acaaagaata
     2821 acgatgaatt aattttctct tcttttttgt aagtaattcg aggataaata attgtttata
     2881 gatcaggaga ctgctaaaat aaggtaggaa taaaaaaata tcagttattt gaggagtgcg
     2941 gcatatggaa atcaaagaag aaaaaatcgt cttgctttat tcaatgatga acaacaagag
     3001 atcggagaaa tgacatggtc agatgcgggc ccagacatca tgatcgttga ccatacattt
     3061 gtagatccag catatcgtgg tcaaaagtta gctgaaaagc tagtgtatac tggagtagaa
     3121 ttagcaagac gagacgggaa aaagatcatt cctttatgcc cttatgcaaa aaaagagttt
     3181 gaaaagaaac cagaatatca agacgtctta cgtcagtcat aagaataaca gctgaaagtt
     3241 ttgaactttc agctgttatt ccatttatat agagttgtca cggactttta tctatgataa
     3301 agttaaagag acgatatctt ttgggaagga ggctgcgata tgtataattt aattttggga
     3361 atcgtgatcg ttttatcgat tgttatggtc attgcgatta tgatgcagcc aagcaagcaa
     3421 aatagtgcag cgagtgcatt taccggcggt gcggatcaac tattcggcaa acaaaaagct
     3481 cgcggctttg aagctgtcat gcagcgatca actgcagtta tgggagctat ctggatgatc
     3541 ttattatttg tcctagcata tttatcttcg aagtagttga ataagcctct cgcaaaacgg
     3601 cgggcggctt tttttattgc aaagagaacg cttaagaaga agttatgaaa gaaactatgg
     3661 taaaatgagg cgaaagaggt gagacgagtg agacaattac caaaacccct ttatgcaaaa
     3721 catggaaagc gagcggtttt gctgcttcac gcttactcag gaagtccaaa cgatgttcga
     3781 atgctcgcac gatttttgga aaaagcagat tatacagttt atgcgccgct ttttaaagga
     3841 cacggaacaa tggagccata tgatatcttg caagaaaaag cagaaagctg gtgggcagac
     3901 actaaaaaag ccatccattt tttacagtct gagcagtttt ctgatattgc cgtattagga
     3961 ttatcaatgg gcggcatctt tgctgtacga gcactagaag aagaatcagt gattggcggc
     4021 ggttttttct gttcgccttt gtctcctgta aaaacaaacg tgcctgaaaa ctttgaaaaa
     4081 tacgtacgtc aagtgctgaa gacagcaggt aaatcagaga aagaaatcaa tgaaaaagca
     4141 gttgcttacc gctcgttagc tgaacaacaa ttaatggata tacaagatca ggcagcaatc
     4201 gtagaaagta ggttgtcaga tatccaacag ccgatatttt tagctcaagc tgggaaagat
     4261 gaaatgatcg accctaatgg cgtatttgaa actgcacgca agttgagccg tcagcgagtg
     4321 acacttcaat ggtatcctga aagtggtcat gtgattacag ttggtacagc aagacgcgaa
     4381 ttagaaaaag acgtcttgga atttttagaa aaattacctt ggaatgagga ataaatatga
     4441 caaaagaaac gataaaagag aaaattctct ttttcatgga aagcagtcgc aaacgcagtt
     4501 tttctatgga agaaatcgct gaaggtttag ggttccaaaa aagcgatgat tttaaattac
     4561 tagtacaaac gattgctcaa atggaaagag aacagagtat agttttcaat aaaaaaggaa
     4621 aagtgaaact tcctttaaaa ccaatcctga tcgaaggaac atttcgagca aatgaacgag
     4681 gatttggatt tgtaacgatt gatcccgaag aagatgacat ctatatccca aaagaagcga
     4741 ctggttttgc aatggatgga gacaccgtag caatcgatat catgaagcga gcaaatacag
     4801 atatggatcg cggagcagag gggaaagtag tcgagattcg agaccgggcg actactcagt
     4861 tagcagggga attcgttgct tattcagaag aagaaataca agaaacagat ctttacggcg
     4921 ttgttatccc gaaagataga aagctcaacc aatttaaagt atatgcagca gcagagggag
     4981 ttcgtccagt tgacggaagt attgtgctga tcgaactgac ccattaccct gaaaaagggt
     5041 atgcgactag tttagaaggg ataatcaagc aagtgattgg tcataagaat gaccctggca
     5101 tggatatcct ctcaattgtc gtggctaatg gtatccctac gaaatttcct gatgatgtat
     5161 tgtctgaagc agatgaagtt ccagatcaaa tcagcgaaaa ggatataact ggacgtagag
     5221 atttaagaaa tcagctcatt gttacgattg atggagaaga tgcaaaagat ctagatgatg
     5281 cagttacggt taaaaaatta gataacggta attattttct tggagtacac attgcagatg
     5341 tttcttacta tgtgacacaa ggcagtcaat tggacagaga agcatatgaa agagggacaa
     5401 gtgtatattt gactgatcga gtaattccga tgatcccgca acgtttatcg aatggtatct
     5461 gttcactgaa tccccatgtt ccaaggctga ccatgagttg cgaaatggag attgatccaa
     5521 atggacaagt agtctctcat gatattttcc caagtgtgat ccaaacaaca gaacggatga
     5581 cctacacagc tgtcaatcaa atcttagaag atcaagacga agaaacgatg caacgctatg
     5641 ctcagctcgt acctatgttc caagaaatgg gtgaattgca ccgaatcctt gaaacgatgc
     5701 gaatcaaacg tggcgcgatt tcttttgagg atcgcgaagc gaaaatcctt gttgatgctg
     5761 aaggacaccc aaatgacatc cagctaagaa gcagaggaat tggtgaacgc ttgatcgaat
     5821 ctttcatgct tgcggccaat gaaacggtag ctgaacatta taataaatta aatctgccgt
     5881 ttatttaccg aatccatgaa cagccaaaag aagaaaaaat gcagcgcttc tttgattttg
     5941 cttcagcttt gggcattctg gtccgaggaa cgaaaggaac gatcacacca aaagatttac
     6001 agcatgtgat cgaaggagta gaagacaaac cagaagctgc agttatcaat actatgttgc
     6061 taagaagcat gcaacaagca cgctattcag aagacaattt tgggcattat ggcttagcgg
     6121 cagattacta cacacacttt acatctccta ttcgacgcta tcccgatcta atcgtccatc
     6181 gtctgatccg ttcttacagt gaagataaaa gtgaaagcaa tcaaagttcg tgggctgcgg
     6241 aacttcctga aattgcagat catagttcta agatggaacg tcgtgcagta gaaacagaac
     6301 gtgaagtaga ttccatgaag aaagcagaat tcatgatgga caaagtggga gaagaattcg
     6361 atgggatcat cagctctgtt gtgaaattcg gcctgtttat cgaactgccg aatacagtag
     6421 agggattgat ccatatcaat gaattgaaac aggactactt ccattttgtt gaaaatcatt
     6481 tagctcttgt aggtgaaaga actggtctga cttttaaaat cggacagaaa gtgcgagtaa
     6541 aagtagtcaa agctgatcca gatgaacgag cagtagattt tgaacttgtt tccgcagaag
     6601 aggttacagc gttggaacgg ccaaaaacac gaaatggaaa atcaggaaaa cgcgaaggaa
     6661 aacaagcagg aaaacgccca gaaagaaatg gcaagaagaa caaacgatat agcgatagta
     6721 agcaaacgtt cggtaagaaa aaagggaaga agccatttta caaaggtgtt aaaaagaaga
     6781 aaaagaaaaa ataaaatgag ttggaggaaa cagctatgcc aaaaggcgag ggaaaattaa
     6841 ttgcacaaaa caagaaagct cgccatgatt attcgatcat cgacacgatg gaagcaggga
     6901 tggtcttgca aggaaccgag atcaagtcga tacgaaacag ccggatcaat ctaaaagatg
     6961 gatttattcg cgtccgcaac ggagaagctt tcttgcataa tgttcatatc agtccttatg
     7021 aacaaggaaa tatttttaat catgatccgt tgcgcacgag aaagttatta ttacacaaaa
     7081 aacaaatcat ccggcttgaa aatgaattga aaaatactgg aatcactgtt gttcctttaa
     7141 aagtctatat tcgtaacggc tatgccaagg tattgattgg tctggcgaaa gggaaaaaat
     7201 cttatgataa acgggaagat ttgaaacgaa aagatatcga tcgacaaatt gatcgaacat
     7261 taaaaaattt ctctagataa tttcattatc ctttttcgca tattcggtgc ttttgctttt
     7321 acttaatgat aaaatttgtt agcatttaat ctgataaaac atgattatca taggtttttt
     7381 cttagatcag gagcaccgtg tataaagaaa aattcgcttc gtttttgact gaaataaaaa
     7441 agtgtctaat tttcatgaaa atgttttgaa ttttctgttt catggtggta tgataccgtg
     7501 tggttagaaa ccgattggaa aaaaccagat acgcacatga attgatttta tgtgaatttc
     7561 ggggaaaaga ggtgaaatgg attggatgaa cgctcgctaa cgttccacat tggaccaatt
     7621 tggtttgatg gtacagtttg tataatggtg ttactgacct gtttgattgt tttcttctta
     7681 gcttactttt ttacaagaaa tcttaagttg aaaccaacag gcaaacaaaa tgcgatagaa
     7741 tgggtcattg attttagtcg aggaatcgta acagataatc tgcctagaaa agaattgagc
     7801 aatttccatt tgttggcatt tacattgttt ttatttgttt ttgttgcaaa caacatcggt
     7861 ttagtaacaa aaatcgtttt acctaacgaa acaacacttt ggaaaagccc gacagcagac
     7921 ccgtttgtta ctttaacttt ggcatttata atgatcttac ttactcactt attcggggtg
     7981 aaaaagttag gcttcaaagg atatttcgta aattcgttct tgaaacccta tagttttatg
     8041 tttccgatga aactgattga agaatttaca aacttattaa cacttgcttt acgtctttat
     8101 gggaatattt atgcggggga agttttgcta accttgattg caaaaatgat gacaagctta
     8161 ggctggttct cattaccatt agcaattcca ttagagatgg tctggatcgc gttctccttg
     8221 tttattggga gcatccaagc atttgtcttt gtcactttgt caatggttta tatgagccat
     8281 aagattgaag tagaagaata atactcggtt aaaaaacaaa ctactattta tctattttag
     8341 gaggaaaaca attatgaatt atatcgcagc agcaatcgca atcatgggag cagcaatcgg
     8401 agccggttat ggtaacggtc aagttatctc taaaacaatc gaatcaatgg ctcgccaacc
     8461 tgaaatgtct ggtcaattcc gtacaacaat gtttatcggg gtagctctag ttgaagctgt
     8521 tcctatctta ggggtagtta tcgccttgat tctagttttt gccgtttaat tgaatcagta
     8581 ttaaggcaga aacaacatcg tttgttactg cttttttaca tggaaactag aaatactcca
     8641 aagaaaggaa ggctcgccta tgctgaatca attggcaatt gcagaagttg gcaatgcgat
     8701 gttaggtaat atcatcgttg tcagcggctc atttttgata ctactggctc tcttgaagca
     8761 ctttgcttgg ggaccaatca gcgatatttt gaaaaaacgt gaagacaaga tcgccaatga
     8821 tttagattct gcagaacaat ctcgcatcaa ctcagcgaaa atggaacaag aacgcgaaca
     8881 acaattgtta gcctctcgtt ctgatgcagc tgatatcatc aaaaatgcga aagaaagtgg
     8941 agaattaagc cgccaaaata ttttgaagga tgctcaagaa gaagcagctc gtctaaaaag
     9001 caaagcccaa gctgatatca ctgtagaacg tgattcagcg ctgaactctg taaaagacga
     9061 cgttgcagaa ctctctcttc aaatcgcgga aaaaatcttg aacaaagaat tatctccaga
     9121 aatgcatgaa tcattaatca atcaatacat tgaaggtcta ggttcttcaa atgaaactag
     9181 ataaatatac agtaggaaga cgttacggga aagctttatt tgaactggcg atcgattcaa
     9241 atcaagcaga agaaatctat caagatctcg taagtttacg tcaaatctat gaacaagtac
     9301 ctggattagg gaatatgtta agtgatgttc gtctagaacc tcatgaaaaa cgagaaatca
     9361 tggacaagct tgtcagcggt tatgatggga tcgttaaaaa ctttttagaa gttgtttatg
     9421 agtataaccg aatggatgac cttttgttca tgatcgaaga atatgaacgt cgatatgatg
     9481 aacatcaagg gttactattg ggaagtgtca caacagcagt cccactttca gacgaacaac
     9541 gaatacaatt agaaaagaat gttgcaaaaa caatggacta tcaatcagtt gaattaaaac
     9601 aaatcgttga ttcttctatt attggtggcg cgattgttga agccaaccat cgagtaatcg
     9661 acggaagcat tcgcacgcaa ttagaaaaaa tgcgtaatca attaaacaga tagtacaaag
     9721 aggtaggtga atcgaatggc catcaaagca gaagaaatta gtgccttgat taaagaacaa
     9781 attgaaaatt atcaaaacgt gctttcagtc gaagaaatcg gtaccgtaac ttatgtaggt
     9841 gacgggatcg ctcgtgcaca tggtttagaa aacgcgatga gtggtgagtt gcttgaattt
     9901 tcaaacggct catacggaat ggcgcaaaac ttagagtcaa atgatgtagg tatcattatc
     9961 cttggcgatt tcgagtccat tcgtgaagga gataaagtaa aacgaacagg taagatcatg
    10021 gaagttccag ttggagaggc cttgatcggt cgggtagtca atccgctagg tcaaccaatc
    10081 gacggactag gtgaaatcgt tactgacaaa gctcgtccag tagaagcgat ggcaccaggt
    10141 gttatgcaac gtaaatctgt taacgaacca atgcaaacag ggctaaaagc gatcgacgcc
    10201 cttgtgccaa tcggacgcgg acaacgtgaa ttagtcatcg gtgaccgtaa aacagggaaa
    10261 acttctattg cgatcgatac gatcatcaac caaaaaggtc aagatatgat ctgtatctat
    10321 gtagcaatcg gacaaaaaga ttctacagtt cgtacacaag ttgaaacatt gaaaaaatat
    10381 ggcgcaatgg attacacaat cgttgtgaat gccggtgcgt ctcaaccagc accattgctt
    10441 tatatcgcac catatgctgg tactgcaatg ggtgaagaat tcatgtacaa cggtaaacat
    10501 gtattgatca tttttgatga tctttcaaaa caagctgttg cttatcgtga actttccttg
    10561 ctacttcgcc gtccaccagg tcgtgaagct tatcctgggg atgttttcta cttgcactca
    10621 cgtttattag aacgtgcagc aaaattaagt gatgatttag gtggcggttc aatgactgcc
    10681 ttaccatttg ttgaaacaca agctggagat atctctgctt atatcccaac aaacgttatt
    10741 tcgatcactg atggacaaat cttcttagaa agcgacttgt tctacgcagg tactcgtcca
    10801 gcggttgatg ccggactatc tgtatctcgt gtaggaggtt ctgcgcaaat caaagcaatg
    10861 aaaaaagttg ctgggacttt acgcctagac ttagcaagtt accgtgaatt agaagcattt
    10921 acacaattcg gttctgactt ggatgcagca acacaagcaa aactaaatcg tggacgccgt
    10981 acagtagaaa tcttgaaaca aaaattgcat gcaccgctag ctgttgaaaa acaagtagtg
    11041 attttgtatg ctttgacaca tggattctta gatagtatcc ctgtagacag tattttagac
    11101 ttcgaacatg aattattcga atatctggat accaatcatt cagatatctt tgaaacaatc
    11161 cgtacaacaa aagatcttcc agaagaagaa gcgttgaaca gtgcgattca ggaatataaa
    11221 gacatgttct tagctacaaa aggaagtaat tcctctacag aagataaatt gaaatccatt
    11281 caaaatgcat agtgaggtga gatgaatggg tgcttcatta aatgaaatca agacacgtat
    11341 cgcttcaacg aaaaaaacga gccaaatcac gcgggcaatg cagatggtgt ctgcttctaa
    11401 gttgacaaaa tctgaagctt cttcacagaa gtttcaggtt tatgcaacaa aagtaagaga
    11461 aatcgttacg catttgactg ctactcagtt aaatgatatt gcctcagaaa atcctagagg
    11521 ggatatcaat tacaacagca tgctgctcag ccgtcctgtg aagaaaactg gttatatcgt
    11581 catcactgca gatggcggtt tagtcggtgg atataacagc tcgatattga aacaaacgat
    11641 gtctatttta gaagaagacc accaatcacc cgatgattac gtgatgatcg caattggcgg
    11701 aactggtgca gacttcttta aagcacgcgg tatcaatcta gcatatgagc tgcgcaatct
    11761 atctgatcag ccaagctttg atgaagtccg caaaattgta aatatggcaa caactatgtt
    11821 ccaaaacgaa gtattcgatg aattatacgt atgttataac catcatatca attcgctaac
    11881 tagtcagttt cgtgtagaaa aaatgctgcc aatctcagac ttagatccag aagaagcaac
    11941 gactttcgaa caagaatata tttttgaacc ttcaaaagaa gaaatcttgt ctcagttatt
    12001 gcctcagtat gctgaaagtt tgatctacgg tgcgatcgtt gacgccaaaa cagcagaaca
    12061 tgctgctggt atgacagcaa tgaaaacagc aactgataat gctgctaata tcattgatga
    12121 gctgacggtt tcttataacc gtgcaagaca aggggctatt acccaagaaa ttaccgaaat
    12181 tgttgccgga gcttcggcac tagaatagta ttgagattgg aggaaaaaag atgagttcag
    12241 gcaagattgt tcaagtaatc ggtcccgttg tcgacgtgga attttcttta gaccaatcct
    12301 taccagatat caacaacgca ttagttgttt ataaaaatga cgaaaataaa tcaaaagttg
    12361 ttcttgaagc agcgttagaa ttaggggacg gagtgatccg gaccattgcg atggaatcaa
    12421 cagatggttt acaaagagga atggaagtca ttgatacagg caaagcaatc tctgttcctg
    12481 taggtaaaga aacattaggt cgcgtattca acgtactagg agatacgatc gatttagaaa
    12541 cacctttccc agaagatgcg gaaagaagcg aaattcataa aaaagcacca gcctttgacg
    12601 aattaagtac aagtacagaa attttggaaa cagggatcaa agttatcgat ttgcttgccc
    12661 catatttaaa aggtgggaaa gtcggactat tcggtggtgc cggtgttggt aaaaccgtac
    12721 tgatccaaga actgatccat aatatcgccc aagaacatgg tggtatttct gtatttaccg
    12781 gtgtaggtga acgtactcgt gaaggtaatg acttgtatta tgaaatgaaa gattcaggag
    12841 ttatcgaaaa aacagccatg gtgttcggac aaatgaacga accaccaggt gcacgtatgc
    12901 gtgttgcttt gactggtttg acgattgcgg aatatttccg tgatgtagaa ggtcaagatg
    12961 tactgttgtt tatcgacaac attttccgtt tcactcaagc tggatctgaa gtatcagcct
    13021 tgttaggacg gatgccttct gcggttggtt atcaaccaac attggcaaca gaaatgggtc
    13081 aattgcaaga acgtatcaca tctacgaaaa aaggttcgat cacatcgatc caagcaatct
    13141 atgtgccagc cgatgactac actgacccgg cgccggcaac agcattcgcc catttggatg
    13201 cgacaaccaa cttggaacgt aaattaacag aacaagggat ttatccagcg gtagatccat
    13261 tggcttcttc ttcaagtgct ttagcacctg aaatcgtggg agaagaacat tataaagtag
    13321 caacagaagt ccaacacgta ttgcaacgat atcgtgaatt acaagatatc attgctatct
    13381 taggtatgga tgaattatcc gatcaagaaa aagtgttagt ttctcgtgcc cgcagagtcc
    13441 aattcttctt gtcacaaaac tttaacgtgg ctgaacaatt tactggtctt ccaggttcat
    13501 atgtccctgt agaagaaaca gtgaaaggat tccgcgaaat cttggaaggc aaatacgatg
    13561 atcttcctga agaagctttc cgaagtgttg gccgaatcga agacgtcgta gaaaaagcga
    13621 aaacactagg ctactagaaa ggggtgcccc atggatcaat atttaacagt aaatgtggta
    13681 actcctgccg gtttggtcta tgatcaccat gcagctatcg tcgttgcacg tacgacagct
    13741 ggtgagcttg ggattttgcc taaacatgca ccaatcatcg ttccattgac gattgatgaa
    13801 gttcgtgtaa aacgaacaga ttcagatacc cacgtcgatt ggatcgctgt taatggcgga
    13861 atcatggaag ttcgtgataa tgttgtttca atcgttgctg atagtgcgga acgtgaacgt
    13921 gatatcgatg tatctcgtgc ggaacgtgca aaacaacgcg cagaacgcca aatcgaagaa
    13981 gcaaaagcaa aacaagatac gaacgaattg aaacgggcaa ctgttgcgtt gcaccgagca
    14041 atcaatcgta tcaaagtatc taagcactca taaaatgaga tgcggatgtt tatccgtgtt
    14101 taagaacagt aaaaagaggt tatgacagaa gtggtcagct tcaagacata agaaggaatt
    14161 tacgaaaatt gcttctcaaa tttttgtgaa atctcagctt atttttcgaa gaagctactt
    14221 ctggaacacc gtatatcaga ggttgtgaaa tcagcgtttt gtcctgagta ttagagaaac
    14281 aaatggaaaa tagttcctca tattttgccg ttttttgagc taataccgag ggtcagatga
    14341 ttgaacaccg tttatttgga ataagggact gcgacaagac ttttgtctca gtcccttttt
    14401 ttgcatattt ttagcattta tttcctaaaa aatgtaaggg gattcctata tttttaagta
    14461 tacttgtttt tccttttata cattttatgg tattatcatt ttattagtta ttataaaaca
    14521 atcgttagaa aggacgtcat tatgcaagta tacggaattg atgcggtgct tcgaatcgtg
    14581 agtcatttgg cgtttatcta cttagccttc tggtctttac gttcgttacg cattgaaact
    14641 tttttcagac caatgcataa tacgcaaatt agaatggcaa tcgtactttt ttcaattttt
    14701 ttagggtaca ctgcaagtaa ttttttctta gaggttatcg ctttatgccg aaatcttttc
    14761 gttagcctgt aaattttaaa aaaaggtact attttaaaag caaggatgtt ataatagaaa
    14821 agattttgag taagtgtatg ctcattggaa ttttttggag ggaacaacat ggaagagatc
    14881 atcgtaagag gtggcaatca attaaatgga acagtaagaa ttgaaggagc taaaaatgct
    14941 gttttgccta ttttagctgc tagtttgtta gcagaagaag gtattacgac attagacaac
    15001 gttccgattc tttctgatgt cttcactatg aatcaagtga ttcgtcactt aaacgtagat
    15061 gtagattttg atgaacaaaa gaatcaagta acaatcgacg cttcaagaca attagaaatc
    15121 gaagcgcctt atgagtatgt tagtcaaatg cgtgcttcaa tcgttgtgat gggtccgcta
    15181 cttgccagaa atggacatgc aaaagtagct atgcctggtg gatgtgcgat tggtaaacga
    15241 ccaatcgatt tgcatttaaa aggatttcaa gctttaggag caaaaattat tcaaaaaaac
    15301 ggctatatcg aagcaattgc ggatgaattg atcggtaaca cgatttattt agatttccct
    15361 agtgtaggtg ctactcaaaa tatcatgatg gctgccgtaa aagcaaaagg aacaaccatc
    15421 attgaaaacg tagctcgcga accagaaatc gttgatttag caaacatttt gaataaaatg
    15481 ggcgctcaag tctatggagc tggtactgaa acaatgcgta ttgaaggcgt ggatcattta
    15541 catgcagtca accactcaat cgtacaagat cgtatcgaag caggtacctt tatggttgct
    15601 gctgcaatga cacaaggcaa tgtgctgatt gcagatgcta tctctgaaca taaccgccca
    15661 ttgatttcta aattgatcga aatgggtgca gaaatcattg aagaagaagg cggagtccgt
    15721 gtcatcggac caaaacatat cttacctaca gatgtaaaaa cgatgcctca tcctggtttc
    15781 cctacagata tgcaagctca aatgacagct atccaattag ttgcagaagg tacaagtgtg
    15841 gtgactgaaa cagtgtttga aaatcgtttc caacatttag aagagatgcg ccgtatgaac
    15901 gctcatgtca aaatcgacgg aaatgtagca atcatggatg gaaaccatga attgcaaggt
    15961 gcagaagtat atgcaacaga cttgcgggca gcagcagcat tagttttagc tggcttgaaa
    16021 gcaaatggaa tcacacgtgt gcgtaacttg aattatctag accgtggata ttataatttc
    16081 catatcaaac tacagcaatt aggtgcagac gtcgaacgtg tagacatgga tcaaacttct
    16141 gctgaaaaaa cagcacaaac gattgcttaa ggaagtggct gaatgagtaa ccaacgatat
    16201 atcttattaa ctttgataaa gattttagtg gtgatcttat tgcttatcct tctttttgtg
    16261 gccggaacga tgatcggata tggtgtcatc ggtggcggca atccatttaa agtattccag
    16321 ccaagtttgt ggattcatat tcgagacttt tttcattgat aaataagaat cacagtggtt
    16381 ctagtcgata tgaagtgagc catgaagcag aacatgataa aagaaaacag aagggaacgt
    16441 tgacgttagt cgcgatccct ttttttagta aaagaaaaga aggaatctaa ttgatgaaga
    16501 agatattgat ttatttagtt agaggatatc agcgctttat ttcgcctgca tttccaccta
    16561 gctgccgtta ttacccaacc tgttccaatt atatgataaa agcaattcaa acccatggtg
    16621 cgctaaaagg gacggtaatg gggactgcac ggatcttacg ctgtcatcct tttgtcaaag
    16681 gcggtatcga ttatgtacca ttgacattcc gattaacgcg aaataagaaa gataaaaaag
    16741 aaccagatta taaaaaggtt gtgaaaaata cgggtagcac tgagcgataa agaaaaagag
    16801 gaaatttatt gtcaaagtaa caactccgca actacttata tgggggacaa aaaatgatcg
    16861 aagaactaaa caagaaagat ttaccatggt ccttgttatt agatgcagat cctgataaag
    16921 aaaaagttca agtatatgtt tccagaggga gtggctggat atggaaagaa aaagaaaaaa
    16981 caataggtgt actgatctat gtggcaaggg aaaaagaata cgaaatcgtc aatgtagcag
    17041 taaccccaac gtatcaagga aaggggattg gcggaaaatt acttgagaca gcttttcaga
    17101 agctttcaca gctagcttca aaccaaactc ggatcattat acgtactggc actactagta
    17161 gcgctgcgtt acacctctat caaaaaatgg gctatgtgga gattggtcga gtcaaagact
    17221 attttatcca tcattactct gagcccattt ttgaaaatgg agatcaatta agggatcaag
    17281 tgattttagc aattcactta cctaaaaata gctttaacta ataaactttc aattcgagaa
    17341 aatgctttca aatgctaaat agatacatta caatagcttt agcaaacaaa aaggagaata
    17401 tttttatggg aatattagtt tttgattttg gtggatcggc tgtcaaatat ggttgttggg
    17461 atggcaaaga gattaaaggt aagggacaat ttgcaacgcc tgaatcttgg gaagaaatga
    17521 aaacgcaatt atttcaagtt tataaaaaaa tactcgtttc ttttgaagtc gaaggaattg
    17581 gaatcagctc tcctggagta gtgaataatg agaaacaggt gattgaggga atcagtgcga
    17641 ttccttatat tcatggattt aatattttcc gagatttgga aactctgttt caactcccag
    17701 taacgattga aaatgacgcc aactgtgccg gaatggctga attttatgaa ggtgctgccc
    17761 gtgattatca agatgttgct tttgttgtgg caggaactgg gattggcggg gcgttgttca
    17821 cgaaaggaca aataaataaa ggggcacatc tttacggtgg agaatttggg ttgatgttct
    17881 tagatggcga taagacattc agtaaacttg gtacagcggt acagatggct tggcgttatt
    17941 gtgaacgcaa aggtctcgat aaaaatgctt ataccggaaa agatgtcttt gaattagcag
    18001 aaactggaga tgcaatagca aaagaagaag ttgagagttt ttatacgtat cttacaaagg
    18061 gattattcag tattcaattt tcgtttgatc cagaagtgat cgtattaggc ggcggggttt
    18121 ctgcaaaaga agggctcatt gatgagatca aaagccgaat gaagaagctg acagaacaat
    18181 tcgatctgca tgatttcgaa ccgcagattt tattatgtga gtacagaaac gatgctaatc
    18241 ttataggtgc agcagcaaac tatctcgctg tacgtcaagg agagaattaa gagctttaga
    18301 gaaggtgcag cttgcataaa agaagagaat gaaatgaata ggagattttt acctaaggaa
    18361 tgttttattt gctgcagtat gataaaatat ctgagaggtg aaaatgatgt caaaaaaaaa
    18421 taaagatatt gaagtgcgta tagaagaagt gaaaaaagat atcaaaggta agaattatga
    18481 agtcactcag ttatttatag ggaaaaaaat gattggtgag atcttagcct atgggccaaa
    18541 agaatatgaa attttctttg gtgaagaaga ttttggaaaa gaaaaaagtc ttgaaaatgc
    18601 gatagaaaca gtgattcgac actggaatct gcacgaataa aaaaatatca aaaaaacttt
    18661 caataaaggg ttgcaaaaat ctggaaaatt aggtattata actaagtcag gttgatacaa
    18721 acctttcgga ggagtagcga agtggctaaa cgcgacggac tgtaaatccg ttccttaggg
    18781 ttcagtggtt cgaatccact ctcctccatt tcattggggt atagccaagc ggtaaggcaa
    18841 gggactttga ctccctcatg cgttggttcg aatccagcta ccccagtata ccacaatcgt
    18901 aagctctcgt tagttcgaga gctctttttt tttgctttgc taccttgttc cttgaagatt
    18961 ctgctgaatt aagatagagt taagttaact acaagaattg gagggatcca catgaaatgg
    19021 aaagaaaaag tagacgaagc agctgaaaag ttatatgatt tggtcaaatc agaaaaatac
    19081 aatattgaag tgaatattcc gaaaaaaggc ggaaaagcgg tccaggtaaa atcaaaacgc
    19141 ccaacgaatc atacaaaaaa atggatggct aaaaaccgct aataataaca aaagatccat
    19201 aagtcggcat tttcatcgat tttagggtct tttgttattt tctaggttga acatatctaa
    19261 aaaattgttt ctgacaatag gagtagggag aacgatgtgt gtctaaatcc tctgttgatg
    19321 gatagaaacc tttatctttt tcagttgtga atcaggtata taccagttat aatagaagaa
    19381 acgaaaggac gggtgtacgt tatgtcgaat caattacctg tatatataca gattcatgac
    19441 caattaaaaa atgaaatcga acaaggtata tggaaagtcg gagaccgtct tccttcagaa
    19501 agagaattag cagtgaaatt caatgtcagc cgtatgacgt tgagacaagc aattcaaaac
    19561 ttggcagatg aaggaatctt agaaagaaag atcggttcgg gtacgtatgt tgcgcgagaa
    19621 aaagtacaag aaaaaatgtc tggtgcaaca agttttacag aaattatgga atcacaaaat
    19681 cgagtaccgt ctagtcggac aatctcttat ttcttgactt cgccaagctc aagtgaaatg
    19741 gaaaaactaa acttgagtaa agatgacacg atcttgcgaa tggaacgtat tcgtttcgca
    19801 gatgatgtcc ctatttgttt tgaagttgcc agtgttccac aaaagctgat cgatggctac
    19861 agcaaagcag agattactga atcgttgtat cgcacgctag aagaaaaagg cgggaaaaag
    19921 atcggtccag cgaatcaaac gattactgct gtgttggctt ctgagaaaat tgctgactat
    19981 ttagaggtaa aacgaagaga tgcagttctt cgtttgcgcc agatttctta ttttgaagac
    20041 ggtacgccgt ttgagtatgt gcgtacgcaa tacgtaggaa atcgttttga gttttatttg
    20101 gaaaaataaa aaacaggtga tccctgattc cttattagaa ataaaagaga atcagaatca
    20161 cctgttttta tatatgatca gttatcagtt gctcgtgata agaaacagaa ccctcttcaa
    20221 attggacttg tccgttcagc agctcaatga tggattcttt aaagtggtta gcactttttt
    20281 catctacagc acagatgacg ctaacttgat cagtatattg gatttctttt ataaaaaaat
    20341 gttggagttc aagataattc tgtaattttc ctagttgcgg atacgtgatc atcacagaga
    20401 tctcctgttg caaggtacct tctacgattc caatgtcaga caatgcttga gagaccgcat
    20461 gagtgtatgc tcgtattaat ccgcctgtgc cgagtttcgt tcctccaaaa tatcgagtga
    20521 ctactgcagc tacattgatc agttgatttt ttttgaggac ttccaacatc ggtacgcccg
    20581 ccgttccact tggttctcca tcatcgctgc ttcgctggat ttcatttttt tctccaatga
    20641 tgaaggcgct gcagttatgg ttcgctttcc aatgttcttt ttttatttct tgaatgaaat
    20701 tttttgcttg gtcctctgat tctattcgtc taagagaaca gataaagcgt gattttttga
    20761 tctcaatctc actttgtcca ttttctttta ttgtacgata gcgctcgatc atcttgtcac
    20821 ctcttttttt cattttcttt attcagtata aataaagttc taggttgttt caacactgta
    20881 acggttgcgc aattgctgta gtatgcgata ataaagacaa aggcaggtgg atctggggat
    20941 gcaggaacga atgaaaaagt acgatgcaat tacgcattat ttgaagaaca atggcggctc
    21001 tcaagtaacg ttgaccttta cccaatttga cgaactgctg tttcccagta acggacttcc
    21061 caaaacagca agggaaagta cagattggtg ggcaaatgat tataaacacc ctgaaaaagg
    21121 tgcctatggc tggataaatg caggctatga agtagttgtc atcaatttgg acaaagaata
    21181 tgtcgtgttc aataaattag tgaaatctag ttggctattt gattaaataa accgcgttta
    21241 gaaaacgttg acaaatttct ttctttttat ataataaagt aacagacgcg aagaaaacgt
    21301 ttgcgtagtt tgttttaaaa aggagagaaa aatatggcta aaaaaacaat catgcttgta
    21361 tgttcggctg gtatgagcac aagtttacta gtaacaaaaa tgcaaaaagc tgctgaagca
    21421 aaaggaatcg actctgatat tttcgctgtg tccgcttctg acgcagataa caatcttgca
    21481 aataaagacg tggatgtgtt gttattaggc ccacaagttc gctttatgaa agctgatttt
    21541 gagaaacgtc tggaaccaaa aggcattcct ttagatgtca tcaatatggc tgattatggt
    21601 atgatgaatg gcgaaaaagt gttagatcaa gcaatcgcgc tcataggtga ataaatagaa
    21661 cagtataact atcgaacaag cgatccaaaa aatagatcgc ttgttttttc gtatattttt
    21721 ttagggcgaa taatatgaat catttttggg gtagaaggct tctgacgaga gatattaaag
    21781 caatagactg tgaggaggta aatttaccaa attatgagaa gatcgcagca gtggaacgtt
    21841 tgggcaactg gattctttgt catcgctgtg gaatgaggac gtccgtcatt gttggacagc
    21901 ttgcagatta cggttatttt tgtacacatt gtctatattt agggtgatgc gacactcaac
    21961 aagatttata tttgtttgat cagcctgaag caaaacctcg agaagtcgtc tttttttgga
    22021 caggacagct tactgaaaaa caaacggaaa tcgcaaagag aatactttgc cattcagaaa
    22081 aaagacatca tcttatttgg gctgtaacag gtgcagggaa aacagagatg ctttatccta
    22141 ttttagtgga aactttaaaa gctggaggaa gagtagcgat ttgtacaccg cgagtcgatg
    22201 tttgtaatga attgttttta cgctatcgtt atgtttttcc agaagaaaaa atcacgttgc
    22261 tccatgggaa tacagcaacg gcttatacct ttacttcttt tgttatctgt acgattcatc
    22321 agctataccg tttttatcgg tcctttgatt taatagtgat cgatgagatc gatgcgtttc
    22381 cttataacgg ggatgctggg ctagctcacg ctgtgcaaac agcaatcaga tcaaacggcc
    22441 gattcatcta cttaagtgcc acgcctgatg agaagttact aaaggaaatc aagcagacat
    22501 ttgagctcca caaacttgcc ttgcgctttc atcggcgctt gcttcctgaa cccgtgcttg
    22561 ttttcatgaa taattggcga caaaaatgtg gaaacaaaaa gaaaatcaac tctttggtgc
    22621 ggatcattca gcaactaatc aaagaaaacc gtatcctttt attttgtcca agtattacga
    22681 tgatgcatcg tttaaaaatc acactgcaag aagcttttcc agaatatgag ataacagatg
    22741 tttcttcaca agacgatcaa cgggcaaaga aagttcagaa aatgcgagaa gcaatatacg
    22801 agatactgtt aaccacaatg atcctagaaa gaggagtcac atttgaaaga atctctgtca
    22861 tcgttttagg agcagatcat ccagttttta ctaaatcctc tttggtgcaa atcgcaggaa
    22921 gagctgatcg taaaggtcct tatacgaaca gtcgagtcta ttttttctat gaagaaaaaa
    22981 cttcagctat tcgaaaagcc tgtcaggaaa tcaaagaaat gaacgaagaa gggaagcaga
    23041 tgctgtgaga tgtagttgct gcggtaaaga catcattcaa aatttaacat tcagcgagat
    23101 catcggagtg tcgaaatcta gacttcctca gacatgttca gtttgccgcg cacaattcca
    23161 tttattagaa gcaaaaggtt gtgcaggttg tcaaaaacca atccatttga aatacgagga
    23221 gacgaaaaag aaagcaaata ctagtttcgt ttactgcaac gactgtcaag aatggaagaa
    23281 gaaatatcct gcatatgatt ttcaacaccg cgcctttttt acgtacgatg aaaagatgca
    23341 ggcttggatc aatcggtaca agtttatggg agatatccga ttagcaggga cttttgcata
    23401 taaatggact cagataaaaa aagattaccc ggcatatatt tattgtccaa tacctttatc
    23461 tgaaaaaagg tggctagaaa gaggattcaa tcaagtaagc gagatgttga aagcagcaaa
    23521 aattcctttt cagatgctgc tcaaaagaga gcaacatctg cttgctcaag caaaaaacac
    23581 gcgaaaggaa agattggaga tgcctcagcc ttttgagctt gccgtacctc tttctaagat
    23641 acaacataaa aaaatattga ttattgacga tgtctataca acaggacaga cgctttttca
    23701 tgcagcagat tgcttgcaga acgcacagcc gaaaatcatc cgaaccattt ctttggcaag
    23761 atgaatcaga tgtggaaatt tgatagcgat ttaatttgca aataacctag agttcgatat
    23821 aatagaatta agaagaggga aagagtggtc cttctccttc ttgattgtgg tagacgaaag
    23881 gggtaatttt tatgtttaga tataatgtac gcggcgaaaa tatcgaagta actgaagcga
    23941 ttcgcgacta cgttgagaaa aaagtaggca aactagaacg ctatttcagt gacgcacccg
    24001 atgcaacggc gcatgtgaac ttaaaagttt atacagaaaa aacagcaaaa gtggaagtaa
    24061 cgatcccatt accttatctt gtattacgtg ccgaagaaac ttctccagat ttatacgcaa
    24121 gtatcgattt ggttgttgac aaattggaac gccaaatccg caaattcaaa acaaaaatta
    24181 atcgtaaatc ccgtgaaacg ggcatgaata ctgcagatgc tgctgcttta ttcaatgaag
    24241 aggacgaaaa cgaaaatgat tctgaattag atatcgtacg tacgaaacgc ctttcattga
    24301 aaccaatgga tagtgaagaa gcagtcttac aaatgaacat gctgggacat aacttcttta
    24361 tttttgaaga tgcagaaaca aatggtacaa gtatcgttta ccgccgtaaa gatggaaaat
    24421 acggactgat tgaaacagac tgatcagcct tacttaaata acaacgaaaa cttgcagcag
    24481 ctactgacag ctgccgcaag tttttttgag tttcctcctc ttttagatga aatatgaata
    24541 aattatgaag ttcttacttt aatacgctta agatatttca attatctata actaatgata
    24601 aaatgaaaag taaagtctac atagtctgga taatacacag aaggaaaagg agattacaca
    24661 acgcatggcc aatttgattc gttcacttat cgaaaacgat aagaaagaac taaaacgttt
    24721 agatagcatt gcaaaaaaag ttgaagcata cgctgaccaa atggcagcat taactgatga
    24781 acaattacag gcaaaaactg ctgaattcaa gggcagatac caaaaaggag aaacattaga
    24841 tcaattactt ccggaagctt ttgcagtcgt ccgagaagca gcaaaacgtg tattaggttt
    24901 atatccatac cacgtacaat tgatgggtgg aatcgtgctt cacgatggaa atatccctga
    24961 aatgcgtact ggtgaaggta aaaccttgac cgcaacgatg ccagtatatc taaatgctct
    25021 gactggcgaa ggggtacacg tagttaccgt caatgaatat ttagcaaccc gtgactcgac
    25081 ggaaatgggc gaactttata atttcttagg attaacagtg gggttgaata tcaactcaaa
    25141 atcttcggat gaaaaacgcg aggcttataa ttgtgatatc acttatagta cgaataatga
    25201 attaggattt gactacttga gagacaatat ggtcgtttac cgccatcaaa tggtacaacg
    25261 tccgctgaat tatgccattg tcgatgaagt tgactcaatc ttgattgatg aagcgagaac
    25321 gccgctgatc atttcagggc aagcagaaaa atccacagct ttatatacaa gagcagacaa
    25381 cttcgtgaaa cgtttgaaag aagaagaaga ttataaaatc gatgtacaat caaaaacaat
    25441 cagtttaacc gaagcaggga tcgaaaaagc agaagaaaca ttcggtttgg ataacttata
    25501 cgacattgaa aatactgcat tgacccatca cttggatcaa gcattgagag ccaactatat
    25561 catgctttta gatatcgatt atgttgtcca agacggaaaa gtactgattg ttgaccagtt
    25621 cactggtcgg atcatggatg gacgccgtta ttcagatgga cttcaccaag caatcgaagc
    25681 taaagaaggc gtagagatcg aagacgaaac gaaaaccatg gcgacgatca ctttccagaa
    25741 ctatttccgt atgtacaaga aacttgcggg aatgactggt acagctaaaa cagaagaaga
    25801 agaattcaga gaaatttata acatccaagt ataccagatt ccgacaaatc gtccggttat
    25861 ccgtgatgat cgtccagatt tgctttaccc aacattacaa agcaagttcc acgctgtcgt
    25921 gcaagatatc aaagatcgct accgcaaagg tcaacctgtg ttagtcggaa ctgttgcggt
    25981 tgaaacatct gagttattat cagatatgct gaatcaagaa cgtattcctc atgaagtgct
    26041 gaatgcgaaa aatcacttta aagaagcaga gatcatcatg aatgctggtc aaaaaggtgc
    26101 tgtgacgatt gctaccaaca tggctggtcg gggaacagat atcaagttag gacttggggt
    26161 aagagaactt ggtggtctag cagttatcgg gacagaacga catgaatctc gtcgtatcga
    26221 taaccagctt cgaggacgtg caggacgtca aggagaccct ggtatgtcac agttctactt
    26281 gtcattggaa gatgatttga tgaaacgatt cggttcagaa cgaatcaaag ctttcttaga
    26341 tcggatgaag atcggtgagg aagatgctgt tatccaaagc aagatgctga cgaaacaagt
    26401 agaatctgca caaaaacgtg tagaaggaaa taactatgac acacgtaaaa acgtcttaca
    26461 atacgatgat gtgatgcgtg aacaacgtga agtaatctat aaacagcgac aagaagtaat
    26521 catggaagaa aaaagcttat ccaagccact aatgaacatg gtcaaacgga caatcagtcg
    26581 tgtagtagat gcgcatacac aattagagaa agaaaattgg aatttggaaa gtatcatcga
    26641 ttttgccggc agtactcttg tccatgaaga tagcattact cttgcagata tcgaaggaaa
    26701 aacagctcag gagatcaaag agtatctaaa cgaacgagca caagaagtat ttaataccaa
    26761 agcggctcaa ctaaatggtc cagagcaact gttggaattt gaaaaagtcg tgatcttgcg
    26821 tgttgtggac tctaaatgga cagaccatat tgatgcaatg gatcaattac gtcagtcaat
    26881 cggcttacgt gcttatggac agaacaatcc attagtcgaa tatcaaacag aaggctataa
    26941 gatgtttgaa gatatggtag gcgccatcga gtatgaagtc actcgaatct ttatgaaagc
    27001 tgagatccgt caaaacgtac agcgtgaaca ggtttctcaa ggaacagctt ctcactcaga
    27061 agacggagat gccaaagaaa atagtaatac tagcgcgaaa aaacagccaa tccatgtgaa
    27121 taaggtcgga agaaatgatc cttgtccttg tggaagcggg aaaaaatata agaactgtca
    27181 tggaaaaaat gcaaactaat ttctgacagc aggattggtg agacaaattc tttttttaag
    27241 aattcgtctc accttctttc tgttatttgc tgattctgtt agactagata taatgaaaaa
    27301 agtatagtga aagaaggaaa aaacatggaa atatccgaaa ttcgaaatct cctgacagaa
    27361 atgcaggaaa aggtcacaag tttcaggagg tctctttgac ttagatcagc tggaagaaga
    27421 catcgcggaa gcagaagcaa aaatggctga acctggtttt tgggatgaca gcgaagccgc
    27481 acaaaaagtg atcagcgaaa ataacgctaa taaagaaacc tatgaccaat tccattctct
    27541 tgccgaagaa ctagaagaaa tcgaattgat ggtggagatg ctgcaagaag aacctgatgc
    27601 agcaatgcaa gaagaagcag aaacacgtat caatgcatta gatgaaaaaa tgaagacgta
    27661 tgaattatct atgctgttag acggacctta tgatcgaaac aatgcgatcg tcgaattgca
    27721 tccaggggct ggcggaacgg agtcccaaga ctggggcagc atgcttttac gtatgtatac
    27781 acgttgggca gagcagcatg gctatcaagt agaaacacta gattatcaag caggtgatga
    27841 agcagggatc aagagtgtga ccctgctgat taaaggacat aacgcttttg gttatctaaa
    27901 atcagaaaaa ggtgttcatc gccttgtacg gatttcgcct tttgactcag cgaaacgacg
    27961 tcatacttct ttttgttcgg tagatgtgat gccagagctt gatgaaacga tcgatataga
    28021 aatcaatcca gatgatttga aaatcgatac gtaccgagca agtggtgcag gtggtcagca
    28081 catcaataaa acagaatctg ctgtacggat cactcacttg cctacaggaa cagtagtagc
    28141 tagtcaggca caacgctcac aattgaaaaa ccgtgagcaa gcgatgggga tgttaaaagc
    28201 taagctttat caattagaag tggaaaagaa agaacaagaa gcagctgcac ttcgaggaga
    28261 acaaaaagaa atcggctggg gttcacagat ccgttcttat gttttccatc cctattctat
    28321 ggtaaaagac catcggacaa acgtagagac aggaaatgtc caagcagtta tggacggtga
    28381 ccttgattta tttattgacg gctatttaaa aatgcatcta caataagaac ccattgttaa
    28441 attgaaataa aattgtaaga ttttgcaagc atgttgaaac attgccatgc tataatagct
    28501 aaagactgaa aaagatatgg agagaacgcc atgattgaaa tgaaggatgt aatgaagaag
    28561 tactcaaatg gtacgaccgc tatccgcaat ctctcgattg tcatcgaaca aggagagttt
    28621 gtctatgtgg ttggtccgtc tggagccggt aaatctacat tcatcaaatt gatgtatcga
    28681 gaagaaaaag cttcaaaagg aactttgaac gtcgcaggtc atgatctaat agcaatcaaa
    28741 aaccgcgaag ttccttatct acgcagagaa atcggcgtgg tgttccaaga ctataaatta
    28801 ttaccaagaa aaacagtata tgaaaatgtt gcgtacgcta tgcaagttat cggcagaaaa
    28861 cctcgagata tcaaaaaacg agtaatggaa gtgctggacc ttgttggttt gaaacacaaa
    28921 gttcgagtct ttcctagcga attatccggt ggggaacagc aacgtgtctc tattgctcgg
    28981 gcaatcgtga atacgcctaa agtacttatc gcggatgaac cgacaggaaa tctggatcca
    29041 gaaaactcat gggaaatcat gaaattatta gatcggatca atgcccaagg aactactgtc
    29101 gtgatggcta cacataacag tacgatcgta aatacgattc ggcaccgagt aattgctatc
    29161 gaaaacggcc gcattattcg agatcaagcg gaaggggaat atggatacga tgattagaac
    29221 ctttttccgc catttattag aaagtatcaa gagtttgaaa cgtaacggct ggatgacagt
    29281 tgcttcagtc agtgcggtaa cgatcacgtt gactttagtc ggtgtattca tggcagttat
    29341 catgaatgca actaaattag ctcaggatat agaaggaaac gttgatgtat ctgtattcgt
    29401 agatatcggt acaaaagacg aagagatgaa aaagctagaa aaagaattga atgacttaga
    29461 tcatgttaaa aaagttgaat tttcaagcaa agaacaggaa ttgaaaaaaa tccaaaacga
    29521 aatgggtgat tcctggaaat tgtttgaagg tgacaataac ccgttatatg atgtgtatgt
    29581 agtaagtgct actgatcctt cttatacaaa acaagtagca gaagaagcag cagatttgaa
    29641 gaatgtttct cgttctgatt acggtggagc ttcctcagat cggattttcc aaatcgctgg
    29701 tgcagttcgg acatggggat tagttgcagc ggcattgctg ctgttcgtag cgatgtttct
    29761 catttcgaac acgattcgga tcacgatttt gtctagacag cgtgaaattc aaatcatgcg
    29821 tttagtcggt gcaaaaaatg gatatattcg ctggccgttt ttccttgaag gtggctggat
    29881 cggtctgatc ggtgcaattc ttccaatttt gatcatcaca tttggttatg catggttttt
    29941 ccaattgatc aatccatcat tattacgttc ccattattca ttgattcatc cacaaaatat
    30001 cgtttggaaa atcaatcttt taatggtcgg cattggtgtg atcattggtt cacttggctc
    30061 gatcatttct atgagacgtt tcttgaaatt ctaataccac aatataaata aaatgagaaa
    30121 gttggacagt ttcgttccag ctttcttttt ttattggcta ggagaataga aggaagcggc
    30181 ttttttccct ttactttaaa aaacaacttg ggtattctta agttggtaga agaagaggtg
    30241 aagccgtgaa aattatcgtt gacaattttt ttacgatcct tttgattatg aatattttgc
    30301 tttcctttat catcgttttt cgagaaagaa aggaaactgc tcaaacatgg gcatggctgc
    30361 tcgttttgat gttcattcca gttgtaggat ttattttata tattttttta ggaagaggga
    30421 tttccaaaga gaaaatcttt gatttgaaga tccaagggaa aatcggtaag aacctggaaa
    30481 ttgaagaaga caaacaggca ttgatgcgag ggctttatcc tcatccgcct actggacaag
    30541 tagatgtgaa acaattgatc tatatgctca cggtatttga aagtacgctc tatacgacta
    30601 aaaatgaaat cactttattt acagatggtc gtgaaaaatt cgatgcgctg attgaagata
    30661 tcaagcaggc agaagaccat atccacttcc agtattatat ttatcgcagt gatgcattag
    30721 gtgaagaagt tcgagatgca ttgacagagg cggcaagacg aggggtaaaa gtcagagtcc
    30781 ttcttgatgc atggggttcc acacaagttt cttccagctt ttttcagaat ttgaaaaaag
    30841 caggcggaga agtcgcattt ttctttcctc tatttgttcc gtatattaat cctcggatca
    30901 attatcgcaa tcatcgtaaa atcgtagtta ttgatgggga aatcggatat acaggtgggt
    30961 tcaatgttgg aaatgaatat ctaggattgg taaagaaatt tggttattgg cgagacaatc
    31021 atttgcgtat ttacggagaa gcggtgtata ccttgcaaaa ccgttttttg atggactgga
    31081 attctcagca tacaaaagaa gtaggctatt ctcccaaatt ttttccgtcc attcacacta
    31141 ctggtgatat agctgttcaa atcgtgacaa gcggaccaga taccgaacat gaacaaatca
    31201 aaatgactta tttgaaaatg atttcgttag ccaaacggga gatattgatc caaacgcctt
    31261 attacatacc ggatggatcg attcatgaag cactgaagtt ggctcttctt tcaggcgtaa
    31321 aagttcatat ccaaatacct aacaaaccag atcatcttct cgtttactgg gcaacgtatt
    31381 ctttcgctgc agagctgatc gagtatggag caaggatcga aacatatgag aatggattta
    31441 ttcatgcaaa gacgatgatt atcgatggtg gcattgtttc agttggctca gcaaatatcg
    31501 atgttcgttc atttcgcttg gactttgagg tcaatacact ggtttatgat gaacgaatgg
    31561 cttcacgtgt aagaaaagct ttttttgaag actcgaaaat ttctacgcat ctcacaaaag
    31621 aaatgtatga aaaccgagga ataatcatca agatgaaaga aggattagca agattgattt
    31681 cgccgctcct ttaaaacata aaaaggacat gagaaccatc aacagatgga gatctcgtgt
    31741 ccttttttaa cggggccatt tctgagagta cgtcagaaat ggagaaagcg tctcgcatga
    31801 gcgaaattaa ctttggggta tctcttgttt tttggggaaa gcaagaaata agctaatata
    31861 tgctattaaa agagacacat ttcaaagcca gtatagc
//
LOCUS       DACGEU010000024        31461 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.024, whole genome shotgun sequence.
ACCESSION   DACGEU010000024 DACGEU010000000
VERSION     DACGEU010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 31461)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31461)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31461
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.024"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(253..705)
                     /locus_tag="IXR40_001041"
     CDS             complement(253..705)
                     /locus_tag="IXR40_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HAQ4360905.1"
                     /translation="MHLNKYWILEEIEKLFVEFGSDAINPYKIIKYSDIDLIETDLGN
                     KTLGQTIHNKRCYVILINQNLSPSMKRFVLWHEIAHVRLHKGICTAAFRANNLSCMIY
                     GIEAEANMFAIEMLTRTIDEQDLSDMSQFQIIEYLGLPHNLEHLVLQH"
     gene            complement(718..1128)
                     /locus_tag="IXR40_001042"
     CDS             complement(718..1128)
                     /locus_tag="IXR40_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4360906.1"
                     /translation="MLLDRIKILLKERSMTLAELERKLNFGNGSMSRWNKSTPSGDKI
                     QKVADYFNVSTDYLLGRTDKRHYYDLTEKDKQDIALQAEKLLEGLNSDAETNYYGEPL
                     DDEDKEKLYDAIQLALALTKVKAKKKFTPKKYRQ"
     gene            1403..1615
                     /locus_tag="IXR40_001043"
     CDS             1403..1615
                     /locus_tag="IXR40_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4360907.1"
                     /translation="MTLKQQVLIALVKKGWSQRELARRMGISITYLRDIFIEKRKPKE
                     RLKQIEELLDIKLEVDSNDQPSEQEA"
     gene            1618..1830
                     /locus_tag="IXR40_001044"
     CDS             1618..1830
                     /locus_tag="IXR40_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360908.1"
                     /translation="MVQRLSKAEFKEKYKYSESTYQRRMKEFKKSRFSEGYNAVTSKE
                     ITIDVDLYEQFRTWRSKNRFRVRAVC"
     gene            complement(2122..2346)
                     /locus_tag="IXR40_001045"
     CDS             complement(2122..2346)
                     /locus_tag="IXR40_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004401476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HAQ4360909.1"
                     /translation="MGKNQHVVPNSNGGWNVKGAGNSKATAHTNTKSEAVKIAREISK
                     NQGSELFIHGRDGKIQSRDSHGNDPHPPKG"
     gene            2424..2612
                     /locus_tag="IXR40_001046"
     CDS             2424..2612
                     /locus_tag="IXR40_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360910.1"
                     /translation="MAYTLQQEHQILGLIKQRRKQLQDDRAALRKADELSDRQAELIA
                     SELEDLRMLEIKNREIRL"
     gene            2938..3273
                     /locus_tag="IXR40_001047"
     CDS             2938..3273
                     /locus_tag="IXR40_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360911.1"
                     /translation="MNKKIENLIEELKRECQKQGVSIICTAQKEGELKSLVYGETTEI
                     LLCLAMQEEHLDENLPLSAHIMRRIAVDAYEQAKNEEENQPSNHTFVINNKEDLADVM
                     TRILKGEFQ"
     gene            3506..4447
                     /locus_tag="IXR40_001048"
     CDS             3506..4447
                     /locus_tag="IXR40_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease"
                     /protein_id="HAQ4360912.1"
                     /translation="MSKSTLEMSHQEWLEDRKKGIGGSDVGTILGLNKWKSPYQLWLE
                     KTGQVVLEESGSEPAYWGNVLEEVVAKEFQERTGKKVRRRNQVFEHPLHPFLRANIDR
                     EVVGENAILECKTANQFLGKEWEGEEVPLSYLCQVQHYMNVLNKDYCYIAVLIGGQKF
                     IWKRIERDQELIDTITEQLVEFWETNVLGGIEPIIDGSQATADFLKEKYADVEDVQTT
                     LPIHFDELVEQKNELKRTKKEIESAIRQVDNEIISELGKREASIGITQKNIISWKFVR
                     TRRMNSKKLAEKYPDVANDEEIYNVTESRRLTEREIK"
     gene            4449..5339
                     /locus_tag="IXR40_001049"
     CDS             4449..5339
                     /locus_tag="IXR40_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HAQ4360913.1"
                     /translation="MATNESLKNQLAAKPQKQVAPGQLGLKALMNTPTMRKKFEEVLH
                     DNANAFMSNVMTLVSNDSYLADSEPMSIMSGALTAATLNLGLDKNLGYAYLVPFNSKN
                     KQTGKWEKKAQFMLGYKGYIQLAQRSGKYKALNVIEVYEGELKSWNRLTEEFEFDPNG
                     RTSDEVIGYVGYFELLNGFKKTVYWTKQEIEAHRIANNKDRDKTKLSGVWASDYNAMA
                     RKTVLRNLLSKWGILSIEMQEATTSDERVQRVQEDGSIIAETEVEEDIPERKEAEVIS
                     EENEDVQTGLFDASNPPLNK"
     gene            5382..6182
                     /locus_tag="IXR40_001050"
     CDS             5382..6182
                     /locus_tag="IXR40_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HAQ4360914.1"
                     /translation="MNTGYVKLHRKVMNSFVWTNPYMYKLWNLCLMKASHENRKILFN
                     GKEIQVNSGEFVTGRDAITSEMNEGVKREHQVNSGSVWRWLKQFEKNGMLNIKSTTKY
                     SVISIKNWSLYQSSEQQMNIKRTTSEQQVHTNKNEKNYKNEKNNKTSSSQPRKKRVYD
                     TDSVYYILAEELFKQICQNQEIKKPNLQSWADDIRKMIEIDKRTENQVRGMIEWSQHN
                     VFWASNILSAKKLREKYDTMAAQANRDYKTKQTKTLEYEKFSTDELPI"
     gene            6197..7048
                     /locus_tag="IXR40_001051"
     CDS             6197..7048
                     /locus_tag="IXR40_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAQ4360915.1"
                     /translation="METVGEIMEKLIQKVLVQRGECPECGQPLYGWRTKNPDGSERCK
                     PTCMQCGYKALRVQEDLQTERIYNESLKARAINFFKGGSVVPNQALFDCTLQNYQIVD
                     QETRQAVEVTKRFVNSVLLGNPSHLVLTGKQGTGKSHLAMAAAWEVLKRSNYDKKILF
                     IGLQEMLDQIKFSYNNPELRKTIEGSLIADIKTADLVIIDDIGSELGKDASDSRAFGI
                     NTLNSFLDARQNLATIITTNLLGEELKKAYGTRTISRMFVNSDGFTMVFSQTADKRIK
                     PVKGAIA"
     gene            7249..7710
                     /locus_tag="IXR40_001052"
     CDS             7249..7710
                     /locus_tag="IXR40_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010781228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAQ4360916.1"
                     /translation="MPKILDACCGSRLFWFDKNNSDVTFMDCRQQYEELSTGHVINVD
                     PDVVADFRDMPFEDDVFDMVVFDPPHLRHVGENSWLAKKYGKLDELWPEDIRQGFAEC
                     MRVLRPSGTLIFKWNEEQIPLSDVLEAIGEQPLFGNKRSKTHWLVFMKKFS"
     gene            7736..8188
                     /locus_tag="IXR40_001053"
     CDS             7736..8188
                     /locus_tag="IXR40_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360917.1"
                     /translation="MKIVLNKCFGGFGLSHEAKMEIFKRKNIEVFPYINNFSYDSDDE
                     YTRYTGQKLGSMDFIYYFKKDPKIDKVTGIYSEIDRLYGIADDSSFSSDSNRGDKDLV
                     AVVEKLGSEASGPYASLKVVDIPDGAEWEISDYDGVETAHYGFQTGSI"
     gene            8294..8488
                     /locus_tag="IXR40_001054"
     CDS             8294..8488
                     /locus_tag="IXR40_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360918.1"
                     /translation="MDASEVVNKINSLKEVFGDVEVVINAQGYDNEFFKQITDISIQQ
                     GMEDEDGNFIDEVAILVTCE"
     gene            8519..8812
                     /locus_tag="IXR40_001055"
     CDS             8519..8812
                     /locus_tag="IXR40_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360919.1"
                     /translation="MKLKDGFYSSGHGIGGLMLDMPTKNPKTRKKPKFKVGDMVRCEA
                     EGFIYPFRGYVEHVYNHSAIIRIENTMECDKWLAKSKENLAVVRLVDMEVIKS"
     gene            8842..9282
                     /locus_tag="IXR40_001056"
     CDS             8842..9282
                     /locus_tag="IXR40_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAQ4360920.1"
                     /translation="MSVIPQLEGEEAIVNILENIDIKQTRKNARRLLKRYRNLERLVG
                     PVKIDFSVMTVTKNLKFTIDSQNEEIIEAISTRDSVIEALTRLSRIHFQVLYYSYCFP
                     NKMSMYQIGEKLGYSDRTIERMKAVALVEFAEAYKSGELISRTK"
     gene            9357..9824
                     /locus_tag="IXR40_001057"
     CDS             9357..9824
                     /locus_tag="IXR40_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HAQ4360921.1"
                     /translation="MVLFDVKKYETPSAKDVDMERTKHNVAVFLSAYLSARCRVGQHR
                     EPKVTASYSLVPPSTADHIFEAERMLIDKEEAQEEFEYLHKLFVRGYSAIQHPHKPDV
                     TERRKKIFYDRYINGLPIYVTAQRNNTSEESVKVESNRIIIQFASSLELVAFK"
     gene            10571..10801
                     /locus_tag="IXR40_001058"
     CDS             10571..10801
                     /locus_tag="IXR40_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360922.1"
                     /translation="MRNYWYVSLTNEYPRTIDDCSVRVVRSVQIKGKYSIVEMGREAE
                     PCEIDACKLVYCGHGFYDEPNIQNNINKNLRD"
     gene            10960..11793
                     /locus_tag="IXR40_001059"
     CDS             10960..11793
                     /locus_tag="IXR40_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small subunit of terminase"
                     /protein_id="HAQ4360923.1"
                     /translation="MARQRDPRRDEAKRIWLESNGEKQLKEIASELNVSDSQVRKWKS
                     QDKWSAELISNVTNGKSNVTNQGGAPIGNQNAKGNKGNSRASPPVGNKNALKTGEYET
                     IFFDTLTDNEKDIYSSLNDDPSFALSEEIRLLKIRQLRMMKRIQQAEAGLNDEEVERL
                     QQLRKIKTPIEKNGKKLEIKREVMQDVQISRKKHRKIDDILSIEDSLTRISNQLAKAI
                     KQMNELYMNEYRTDLIKAQTDKIQAETNEIGGNNSGEEIEEWKQAVLNAANKRAVKEN
                     E"
     gene            11786..13201
                     /locus_tag="IXR40_001060"
     CDS             11786..13201
                     /locus_tag="IXR40_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HAQ4360924.1"
                     /translation="MNNEFIPFADIGSAIDYYYDKPVAFCQDILHLNPDEWQENVLND
                     LAEFSKVSVRSGQGVGKTALEAGAILWFLTCRPYAKVIATAPTMKQLYDVLWAEVAKW
                     LNDSLIKNLLKWTKTKIYMVGDSERWFATARTATKPESMQGFHEDHMLIVVDEASGVS
                     DPIMEAILGTLSGFDNKLLMCGNPNNIEGVFYDSHNSDRDKYRVHKVSSYDSKRTNKD
                     NIEMILKKYGKESDVARVRIFGEFPKGALDSFISLETVELATEKQISDSLVNKTKVAH
                     IGVDVARYGDDSTILFPRIATRALEYEKYSKRSTMETTGYVINMAKNLMSQYPSIDKV
                     MIKVDDTGVGGGVTDRLEELIEDKHYPFEVFGVNNGSTSEDDFYDNLGTQLWGNIKEM
                     LEENMTANLNGEQPVIELPSDSSLIKELSTRKFKMTSRSRIRLESKDDMKKRNIGSPD
                     IADALALAFYEPPSHYQFIQF"
     gene            13213..14742
                     /locus_tag="IXR40_001061"
     CDS             13213..14742
                     /locus_tag="IXR40_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HAQ4360925.1"
                     /translation="MISTVLSLERYKKLRVKYATQIEDGMFDPNGFIEDMKPFFADRE
                     RKYLAYTSEKNEIDNRPKPNTDIVKVNNKLHAGMYSIVVDQAVNHFTGIPIKWDYDVS
                     EQKRTLIQRLKDKFLKNDIELPTVPEAFNKLTSNLDSMRFAMLDSETATFQGACGVAF
                     RLLEPVEEDDGWKLRASNIEPWRAERYGNAGIYIKEKYDSYQKKFFQEMKVMTRNKIL
                     TYACYGDLNFVTSGTFKKIDETDNPLGTITLAEFKNNTNRYCDFEVAEEIGDAIDRAL
                     SDQQNEIEQFKLAYMLVTGTTMSKGTAKEMMNQLGIINLKAPTAKAEYVTKNLAKDFN
                     EYHMDLLKKQFYTICKAIDFNDEVFKSNSSGEARKWQIISLEAKTNTKEQYFREGLKE
                     CAETIAAFLKFHDKVEIEPEKIIFTFSRSLPTDLSYLAEALPKLAPYVSKRTIQSQIP
                     FVTDVDYENEMMELESGSAYPDSEYNFGGGGNSDDRNEVLDQTSRTGGSSKAQTRKSD
                     T"
     gene            14834..15712
                     /locus_tag="IXR40_001062"
     CDS             14834..15712
                     /locus_tag="IXR40_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head morphogenesis protein"
                     /protein_id="HAQ4360926.1"
                     /translation="MMEFYSTSNQKKYREYVEKNYKSLKMYDAKYKEFIDEFFPPFDY
                     AKVNRLLQIRSDVFKILAEYAMDADVNQYFSDRLEEILQRTYSSNANVFVQLLNVDIP
                     NYLPENEIKHYLNYPWSGKTFSRRLWGNISSLEQKLSNAIVKSVASGEGVIHALNTMR
                     LDSEICDMFKLEESKYNKAIENLVRTEYAKFAQDGIEKSYLETGIEEYNVLTAKDERV
                     CRICGGKASKNPYKLKDAVIGENRAPFHSRCRCTDVPNLPKLGKDIDEEYDRLFGDLL
                     DEFAHDSFGINLKRRK"
     gene            15714..16031
                     /locus_tag="IXR40_001063"
     CDS             15714..16031
                     /locus_tag="IXR40_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360927.1"
                     /translation="MKDFFEAVLTINVNADIAEAYKTAIESENHPNGLRDHWNGNYAY
                     VVIGDQTVNYQDNTPVDKNTVNLTIQLLSHSLPNLKETVDWYEKMGCIVVRTDYKEGK
                     SSN"
     gene            16080..16781
                     /locus_tag="IXR40_001064"
     CDS             16080..16781
                     /locus_tag="IXR40_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HAQ4360928.1"
                     /translation="MVEWWGATIKTQSNAGRENESWGERRMSMKHKSLMPMNLQYFAE
                     GDDQKFSFDDFKSFVESNEEAQKFIQSQSQSVADKQLEAWKQNNLDKIKQDTIKEYEE
                     SKKNKSPEQIQLEKLQAEFEAEKALRVTSDNKAFVAEQIAGLELDGELKESISQFMLN
                     NLVSSDTDFTKNAVEGFTSVLNAINEKHADALKELQMKSAFGGTQQSNNQVQQNNETL
                     TNPEEQLGQILQQFN"
     gene            16796..17686
                     /locus_tag="IXR40_001065"
     CDS             16796..17686
                     /locus_tag="IXR40_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5309 domain-containing protein"
                     /protein_id="HAQ4360929.1"
                     /translation="MKKTSLNNLEYLDISPAINAMQVPNTPFLSYLLGAGKTEPANST
                     EIKWREYDINNDDSSEKLEGGEYPDAESGRTWFNNYTEIFRKSTSVSGTLDAINVNGV
                     GNELTNQVALRGMEMKIDLNRKLITGVKADENGSKGRRMNGILNLINSANKAETATAG
                     AVTRKDIDTLFKLMYEKGYMGEKLCLISPDMQELMTDELDGKSTKIVQFGERVTFGLQ
                     IGNIVSNYGTGIALLEPSLPKGTIAAIDTNYVKLRPLREWRAEELAKTTDSRRIGLVG
                     EYSLEYNASNSGAILNLKSE"
     gene            17709..17924
                     /locus_tag="IXR40_001066"
     CDS             17709..17924
                     /locus_tag="IXR40_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360930.1"
                     /translation="MIGGITVVKKDETKKDEVVKYRVGKTKNFVGFVHPKTRRFITAD
                     SNNEFIISIDDKEAIAILEDAIDVNEI"
     gene            17936..18277
                     /locus_tag="IXR40_001067"
     CDS             17936..18277
                     /locus_tag="IXR40_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360931.1"
                     /translation="MDESLKTEIIESTKEDFPDLSEERITNLLEIILLEIESYNTCKN
                     DISWEKLKSVISEVLYKIIKNESEKTVSSVRRGDTTISYASTTNDVSELLLGYGDLIR
                     RVIGCGGLEFF"
     gene            18277..18648
                     /locus_tag="IXR40_001068"
     CDS             18277..18648
                     /locus_tag="IXR40_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360932.1"
                     /translation="MNEADILETTYEDSCIIERLTDIEDSNTNITIQDYKKVYDNPIS
                     CALSQGQIDGLAVIEDGEMVNVSTDTYKLFVHPKIKLKKGDRITITQKASGLIFSLFA
                     TKPFYYPSHCEVNLIGSEKNG"
     gene            18641..19036
                     /locus_tag="IXR40_001069"
     CDS             18641..19036
                     /locus_tag="IXR40_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HAQ4360933.1"
                     /translation="MGNLKYESNAEKIIENFKNMTVIAQKEGISFVNDSMNKVVSLAK
                     PLTPVKSGNLRRGYRVVKARKLSSGRIVGEVINNEHYFKYVEEGHRTKNGGFVKGKFM
                     LTRATNLANMSYIPRRFKQMAIKIVKKGK"
     gene            19038..19415
                     /locus_tag="IXR40_001070"
     CDS             19038..19415
                     /locus_tag="IXR40_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360934.1"
                     /translation="MKDEIIAAISSKLKEIYPDGTIYLDSVMQSTKDFYFVLSVMESG
                     TENVGIDIQNVSFLIDIALIDNNPNRNLINELVSRCGTFFNTITIDEQILFPKAYLPD
                     EADGVQHIRFTLEFPQYIEWSER"
     gene            19416..20024
                     /locus_tag="IXR40_001071"
     CDS             19416..20024
                     /locus_tag="IXR40_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAQ4360935.1"
                     /translation="MGEKRSKTGIISVEKPTWFPLEDETGNFPVYGTALPMGTAVSIK
                     PTANYETTQDYGDSVVQDQFTAFGGAEVELEANGYTHKVLSTITGGKIVKGGALRSGE
                     DIAQDGAFAYRRKKSNGKYRYTVFYKGQFALDSDETSTIEGSKVSFTHPTWKGSFVDV
                     PGLGYMYSVDEDDEGVDKAMIGNWFTKVAIPIEEAELSGGTE"
     gene            20024..20365
                     /locus_tag="IXR40_001072"
     CDS             20024..20365
                     /locus_tag="IXR40_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360936.1"
                     /translation="MSKYQTTIKLTKKDEEGKYEQVQFKSAEFLPGTVVEDAAGVMEE
                     MQTATDKQSVKKALSRAYSFIADTLFEGQFTGEDYCKGIDAREIASLTGKLLKSVTAG
                     FDETYTETKKK"
     gene            20607..23396
                     /locus_tag="IXR40_001073"
     CDS             20607..23396
                     /locus_tag="IXR40_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HAQ4360937.1"
                     /translation="MILDESGFTAGMNNAVKKLNSFDETIERKSRNSGSSLGSIWKIF
                     AGSFLASGVTRIVGAGFDLIKGSISGAVDRVDTMNNALRNFQNMGFSNSEIMKNIGKN
                     GLLSQGIQGLPTALNDAISHVQLLASSTGDLTRSTQIFKALNDGILGFGGSTDQVNEA
                     VIQLSQSFSNGKVDAQTWNSMINAQLGPTLSAIAKKMGITMGDLKEGLSQGKISVEEF
                     QNQLIEMDTKGGGGLKSLSQIAKDSTKGIKTSIQNAKTAVTRGVGEVIEGLNKALVDS
                     DLGGFKGIIDKVGSSMESFLKVIAANIPTAVSFLSNLFNEIQKFGSALKFMMPFLVPA
                     ATAFGAFMFQLKGIPAIIKSFNNFKNAIIGVGNSLKIMGAIAAANPFVLIIGAVVGAI
                     AVFGYFMATNEELRNKVISIWNDVKDSVIGVLKNIKDWGIDTWNSAKEMASNAVEGVK
                     DAWSGTKEWFSNTWKGIKDGATGLFDKTVETSRNAVDSVKNAWSNMKKWFSDTWQSIK
                     DSAREKWNGIKGSIMSVAGPLITGIKNAFLHVTFYLETLWNNLVEIGKNVFEILKNVI
                     LAPVLFITSMISGGWEETKNNMIAVWNNIKESAINIWESIKNIFVSYFTNIYFAALNI
                     WTGFKLTLINIWNEVVNQAKSIWLNIKYFFINLWIDIKYFAIQKWIELKFSIIQTWID
                     LKYNAITTWNNIKQFFKDTWKNIKDTAYNTWISIKNTMINTWNNIKDSFWNIVTGIVN
                     SAENAWTNLKNGVSNAINRVKEIFNSLREVNLFEIGKNIIDGLINGVKEKWNALKDTI
                     KGIAGNIKNWIKGALDIHSPSRWMRDMVGKNIVQGIIVGIDKEQSKLDQTMTNLVKTP
                     SVQPVVNGISHLPITQTKQNISASETKEIHLHLNVYGDLPDSMVRKITTKIKTELTRQ
                     MKRDAGAVGGTLYAT"
     gene            23386..24126
                     /locus_tag="IXR40_001074"
     CDS             23386..24126
                     /locus_tag="IXR40_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAQ4360938.1"
                     /translation="MQLKRGQFFINQHYSSEFNVYIQNRPASVSASRVIELREREGND
                     SIIIDKGYYKNVTRKIECYYKAPSIDMVQEWEDRITEWLDMSSYSDFILYYDEQYIYQ
                     AVVIEGPEFKGTRKTGNIVPFEFTVSIRPFKENYNGRFTIRQTETFEIYNPEKYSSKP
                     LIKLSGSGDASFYINKDKYDLKSLDRELFIDSKLEEAYRKLDGNLEHQDQVTLFLDFP
                     FLYPGKNEIKWTKNIHSFEIMPRWWRKV"
     gene            24123..26885
                     /locus_tag="IXR40_001075"
     CDS             24123..26885
                     /locus_tag="IXR40_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HAQ4360939.1"
                     /translation="MKPRIYSPTETDFSTNGLGILKDCTRCGIYEVANGKYELELDYP
                     LGTRFDEYFENDYQIKAKPNDQEEYHIFFIDDKDIDTFLNTVTIYAQSRTNRLGRRVV
                     TLVEVDSKTGQEAISIIETKMDKKSDIRLYSDITAVSSTIFEARNVLNCIAGEQGSLL
                     QYWGGEIKREPFKLSLLKRRGRNNVGTIRYGKDMSGLKVKLDWTGIKTRIIPYADPQS
                     EVGTTNRIYGSPVDSAYINNYPDVYTEHVQFTEEQGVKDIKSLNKIAKNYFKTINPGC
                     DKPKVSITVEFDKLTDSEEAKEFAKIRNYGLFDTFKIYHKKYNIYLESKVSGLQYDSL
                     SEKTLKLEAGDIQVAFYQQQAVTIQDKLKDYATNNYMSDFNDYVSSMITGQGSAGGYV
                     VLWPKEKPSNIFIMDNPDLEKAREVLRMNKNGIAFSKKGWRGPFNSAWTLDSIFNANF
                     IQTGLIKADIFQNSFNKTGDVLKLVNGLLQIWNNKKKIMELTKKGMEFWNSKGSIGTI
                     GTTDSVGNPFPGASTPTPIEDNSLVIRTNGDGKYILISPKVGKGLVLLGNGKAIYFGD
                     LDVQGKLTVKGKEIIPGQGGGPSGGGESTGGYPSELKTDAEKRAWRIYDILCNNGFTK
                     QSACGILGNIQQETGGTFDPDTVQIGGPAYGLVQWDGSSYPLVGPATWDGKVYVQNLF
                     NAAGIKEPITSLDAQVRLLIWTFTNGQWMGVVQPTTVDGFKACTDPRQAAYAFERNYE
                     RPAATHPERQDYAVNWYNKFKDLKPGGATGEAGLKHLESLIGQRIGNGQCYGLSAEYS
                     GYLGGCGMGAGTKYGLTHVIGNTSAASDIGIAYDWSAVGWKVIQNPRYDQLVVGAIIN
                     WARGGQVGSWFADGTYGHTGVIRGLANGRMQTYEQNTELGMICGKLDRQYYSASAISS
                     IVIPPK"
     gene            26898..27806
                     /locus_tag="IXR40_001076"
     CDS             26898..27806
                     /locus_tag="IXR40_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HAQ4360940.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETKIVDAKKGKINYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQDFSYFVINAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKEE
                     FERWRQEQEHSFQDWREGQESDYLAWFESIKDILKTIDPGGVMLAELTDARVDIQGVR
                     HASISERLLADMDYLYQKLRATLFTIEYGEIEVTDILQDDLFSDNHEVEKVGTVAFPI
                     EEGALIIATVDDPKQNVFTLEKVGVI"
     gene            27806..28426
                     /locus_tag="IXR40_001077"
     CDS             27806..28426
                     /locus_tag="IXR40_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360941.1"
                     /translation="MAKTKRMMETDEKTGVQRQFFPITHASAVLGLEEIIAGEATVLS
                     VNGKIGAVVITKEDLGLENVLTELPYASEEDDGIITAEMYQKILNSGEGDYVLPVATI
                     DRLGGIKVGELLTIDETGKVSAVRQSDVNFSLELKEKLDSLKNYTAGENITIDEDGTI
                     SSTGGSGTGGVNQSYVDQKFQEAVNQAENYTNERIPNFTFEKIGEV"
     gene            28430..28879
                     /locus_tag="IXR40_001078"
     CDS             28430..28879
                     /locus_tag="IXR40_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360942.1"
                     /translation="MTDIVKIKQSNVQVYPQTHWNAIEGKPTTVKGDKGDPGQAATIT
                     IGTVSSGSTASVTNVGTSSAARFNFVLPKGDKGDPGINATTTAVATTTANGLMSSTDK
                     TKLDGIAAGAQKNPGNATTTTAGLMSATDKAKLDGLANITFEKVGTV"
     gene            28879..29373
                     /locus_tag="IXR40_001079"
     CDS             28879..29373
                     /locus_tag="IXR40_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360943.1"
                     /translation="MADIVQLKEDGVAKYLKTHVEAIDGKEALVQTDGDQAIAGHKNF
                     SGSVTINNKRVLTTDDNRYEVVNLVVTNGNTGTAKLYREGKTVSIYFVALNGKSSGGN
                     DSVILTVPEGYRTPISFEQLVGSIDRSTLNSAQLSIGADGAIKWRRNSSYGSAYSFVI
                     TYSI"
     gene            29387..29818
                     /locus_tag="IXR40_001080"
     CDS             29387..29818
                     /locus_tag="IXR40_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360944.1"
                     /translation="MKVVYKSIKPYGFEQIILNNQENIPENCTEIKPPVPNWRPRFDF
                     DKKQWVELATEEEKKGNAVDSVDELANIKALYETLKAENDELKQLNSKAMLNNVAIKQ
                     ENVLLKEKSESLAQLNSKTMLASVQNTKEIEEIKKQLQGGK"
     gene            29820..29957
                     /locus_tag="IXR40_001081"
     CDS             29820..29957
                     /locus_tag="IXR40_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HAQ4360945.1"
                     /translation="MYSYEDIKLMYDWGCFTNEQVMVFVPLCITEEEADKIISKEESA
                     S"
     gene            29995..30288
                     /locus_tag="IXR40_001082"
     CDS             29995..30288
                     /locus_tag="IXR40_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360946.1"
                     /translation="MINLGEWGAIAGSITAIVSLILLVIKPITASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHTEKLVEHTQQIKTLFRERRK"
     gene            30285..30509
                     /locus_tag="IXR40_001083"
     CDS             30285..30509
                     /locus_tag="IXR40_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin"
                     /protein_id="HAQ4360947.1"
                     /translation="MNNKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIIT
                     GFGAFLGSVLGVSNRTYKMFSAESEEGGNK"
     gene            30506..>31461
                     /locus_tag="IXR40_001084"
     CDS             30506..>31461
                     /locus_tag="IXR40_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAQ4360948.1"
                     /translation="MKKKITITAMSLLTALFLLPINTFAYTINDEYNLAPNQGDSRLA
                     IPNKIILHETGIDAPARNVAANMKNNYNGSNSYTTDVIGDGGIVYRVGEQGYVSWGAG
                     NANPYAPVQIELQRTYDKALFEKNYRAYIEYTRDSAKKYGIPLTLDQGTSLFTKGIIS
                     HLWVTNYVWGNHTDPYGYLSQMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGA
                     ANPTLTDGTNHAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADG
                     IYRPDVNQAYNTSGNVGYHVSFNMRNFPSKKVYVMMRATNDP"
BASE COUNT        11277 a         4565 c         6497 g         9122 t
ORIGIN      
        1 tgtttcttcc ttacttaata taaatctttc tctatcatgt aatttattta gtttttcatc
       61 atttttttgt tctaattcat aagcttcttt ttttattgtg ttagctttcg acagtttagt
      121 gattcctata attaataaaa taagtccaat caataataac attcaaaact cctcatttct
      181 ttgatataat tattgtagag tttactcaga aatgaggaaa gagtccatgt gaaagcatgg
      241 gcttttttat ttttaatgtt gtaatactaa atgttcaaga ttatgaggaa gccctaaata
      301 ttcaataatt tggaactgac tcatatcaga taaatcttgt tcatctattg ttctagttaa
      361 catttcaatt gcaaacatat tagcttcagc ttctatacca taaatcatac aactaaggtt
      421 gtttgctcta aaagctgctg tgcaaatacc tttatggagt ctaacgtggg ctatttcatg
      481 ccataataca aatcttttca tagaaggtga taggttttga ttaattaata tcacataaca
      541 tcttttattg tgtatcgttt gtcctaatgt tttattccct aaatcagttt caattaaatc
      601 tatatcagaa tatttgatta ttttatatgg attaatcgca tcagatccaa actctacaaa
      661 taatttttct atttcttcta atatccagta tttgtttaaa tgcataccaa agcccaccta
      721 ttgacgatat tttttaggag tgaatttttt ctttgcttta actttggtta aggcaagtgc
      781 aagttgaatg gcatcgtata atttttcctt atcttcatcg tctaaaggtt caccataata
      841 atttgtttca gcatctgaat tcaagccttc aagtaatttt tcagcttgta aagcaatatc
      901 ttgtttatct ttttctgtta aatcataata atggcgttta tcagtacgtc ctaaaagata
      961 atcagttgat acattaaagt aatctgcaac tttttgtatt ttatctccag atggagtact
     1021 tttattccat ctagacatgc ttccatttcc gaaatttaac tttctttcaa gttctgccaa
     1081 cgtcattgaa cgttctttta ataagatttt tatacggtct aatagcatag gatatgcatt
     1141 cctttcaaaa taccgacaaa aaaagtattt ttctgcaaat tatctattta caaatagaga
     1201 atttgcagtt atactagttt tgtaagcaag atatttacgg catacaaaga ctaaaagcaa
     1261 taaactaata gtctccccag acatcagtaa gctcgctttt tgtgcgctgt attttgtatg
     1321 cttacataat agcatatttg cagtttttgt caaacttatt agacaaaaat attagaaaat
     1381 attcgataag ggggtatgaa gcatgacttt aaaacagcaa gtattaattg ctttagtaaa
     1441 gaaaggttgg agtcaaagag agttagctcg acgaatgggt atatcaatta cttatttacg
     1501 agatatcttc atcgaaaaaa gaaaacctaa ggaacgttta aaacaaatcg aagaactttt
     1561 ggatatcaag ttagaagtag attctaatga tcagccatca gaacaggagg cgtaaaaatg
     1621 gtacaacgtt tgagcaaagc ggagtttaaa gagaaatata agtattctga aagtacttat
     1681 caaagaagaa tgaaggaatt taaaaaatca cgttttagtg aggggtataa cgcagttact
     1741 tccaaagaaa taacaattga tgtcgattta tatgaacagt ttagaacatg gcgttctaaa
     1801 aatcgattta gagttagagc tgtttgttaa tagctaaaaa atctaaattc accacttctg
     1861 aaaagaggag ttgctgctct cctttcaagt ttgccaaagt ccacgttttt tcattttggc
     1921 aactcctctt cttggaggtg gtgacggcga gagacgaagg agggatgaca tgaaggaaga
     1981 atcaaaaata gggattttga atgagaacaa ttacacaaga ttaattattg aaacagaaga
     2041 agggaaaaaa gtagcagaag ttacattgac cgatgcaact cctgctgacg gttatcgtat
     2101 tcgattaact cctaaatatg attaaccttt tggtgggtgt ggatcgtttc cgtgactatc
     2161 acggctttga atttttccat ctctgccatg aataaatagc tcagatcctt gatttttaga
     2221 aatctctcta gcgattttta ctgcttctga ttttgtatta gtatgtgcag tcgctttaga
     2281 atttccagca cctttgacat tccaaccacc attggaatta ggtacaacat gttgattttt
     2341 tcccatagtt ttcacctcca tttctataga aatattttat caaatagaaa tggagaaatt
     2401 caataaacga aaggagaagt gatatggcat ataccttgca acaagaacat caaattctcg
     2461 gtttgattaa acaacgcagg aaacaattac aagatgaccg tgcagcgctt agaaaagccg
     2521 atgagctatc agataggcaa gctgaactaa ttgcttctga acttgaggat ttgagaatgc
     2581 tagaaataaa aaatagggag attagattat gaagaagaca gacacacttt ttataggatt
     2641 cattttgggg ttattagtga ttgtagcgca ccaaagtatt atcgggggaa gcttgttcgc
     2701 agcattgatg gttttaatca atctgcttga ttcaaaagaa aggagcaact atggcacgag
     2761 aagaagcgct aaaaatcggt aaagtgattg ctgataatcg gtggggaaat agccgcccta
     2821 ttattttaag caagcaacat atcgaaaagc aaaaagcatg gcaacaaata aaaaagtgac
     2881 tctgccagcc agcaaagagt cacatacaaa tttataaaac taggagaatt atatcacatg
     2941 aataagaaaa ttgaaaatct tatcgaagaa ttgaaacgtg aatgccaaaa gcaaggtgtt
     3001 tctattattt gtacagccca aaaagaaggg gaacttaaaa gtctcgttta tggtgagaca
     3061 acagaaattt tactttgtct tgctatgcaa gaagaacatt tagatgaaaa tctcccattg
     3121 tcagcacata ttatgcgtag aattgctgtg gatgcttacg aacaagcgaa aaatgaagaa
     3181 gaaaatcaac cttcaaatca tacttttgtt attaataaca aggaagattt agctgatgtg
     3241 atgactcgta ttctcaaggg ggaatttcaa tgatgaatga aaaaacaatt gatctactca
     3301 ttattttatt tttcacgtta gtgattgtag cgaaaagtta tgtaatcttt ggcttgttat
     3361 tcgcaattac catgcttgtg ctttgcgtgt tagcaagcag aaaagaggtt aaacatgaac
     3421 gagttagcaa atcttgacaa ctatttaact gatcctgatt atgctaaacc accatatgaa
     3481 gcaccaattg atgaggagga tgaagatgag taaatctacc ttagaaatga gccatcaaga
     3541 atggcttgaa gaccgtaaga aaggcatcgg aggttcggat gttggaacaa ttttaggatt
     3601 gaataaatgg aaatctcctt atcaactatg gctagaaaaa acaggacaag tagtacttga
     3661 agaatcagga agtgagcccg cttattgggg taatgtttta gaagaagtgg ttgctaaaga
     3721 gtttcaggaa cgtacaggca aaaaagtacg cagaagaaac caagtatttg aacatccatt
     3781 acatccattt ttaagagcaa atattgatcg ggaagtagtg ggagaaaatg ccattctgga
     3841 atgcaaaaca gccaatcaat ttctcggtaa agaatgggaa ggcgaagagg taccgcttag
     3901 ctatctctgt caagttcaac attacatgaa cgttctaaac aaagactatt gttacatcgc
     3961 tgtcttaatc ggtggtcaaa aatttatctg gaagcggatt gaacgagatc aagagctgat
     4021 cgatacaatc actgaacaat tagtagagtt ttgggaaaca aacgttcttg gaggtatcga
     4081 gccaattatt gatggtagtc aagcgacagc tgatttcttg aaagagaagt atgcagatgt
     4141 tgaagacgtt caaacgacgt taccaattca tttcgatgaa ctagttgaac agaaaaacga
     4201 actcaaacgg actaagaaag aaattgaatc agctatccgt caagtagaca acgagattat
     4261 cagcgagcta ggtaaacgtg aagccagtat cggtatcact caaaaaaaca tcatcagttg
     4321 gaaatttgtc cgtacgagac gtatgaactc gaagaaacta gcagagaaat atccagatgt
     4381 cgcaaatgat gaagagattt ataacgttac tgaatcaaga aggctaaccg aaagggagat
     4441 caaataatat ggcaacaaat gaatcgttaa aaaatcaatt ggcagcaaag ccacagaaac
     4501 aagttgcacc aggtcaatta ggacttaaag ctttgatgaa tacaccaaca atgagaaaga
     4561 agttcgaaga ggtgcttcat gacaatgcta atgcttttat gtcgaatgtt atgactcttg
     4621 tatctaatga cagttatctt gcagatagtg aaccgatgtc tatcatgagt ggtgcgttaa
     4681 ctgctgcaac attaaatctt gggctagata agaatttagg ttatgcatat ttagttccat
     4741 tcaatagtaa aaacaagcaa acaggaaaat gggaaaagaa agctcaattc atgcttggct
     4801 ataaaggata tatccaatta gcccaacgat caggtaaata caaagcatta aatgtgatcg
     4861 aagtttacga aggagaacta aaaagctgga accgactgac agaagagttt gagtttgatc
     4921 caaatggtag aacgtctgat gaagtcattg gatatgttgg ctatttcgag ttactgaatg
     4981 gattcaaaaa aactgtctat tggaccaaac aagaaatcga agctcatcgg attgctaaca
     5041 ataaagatcg cgataagaca aagttaagtg gtgtgtgggc atctgattac aatgcaatgg
     5101 cacgaaaaac tgttttgaga aatcttcttt ctaaatgggg aatcttgtcc atcgaaatgc
     5161 aagaagccac cacatcggat gagagagtcc aaagggttca agaagacggc agcattattg
     5221 ctgaaacaga agttgaagaa gatattcctg aaagaaaaga agcagaggtt atatctgaag
     5281 aaaatgaaga tgtacaaact ggattatttg atgcatctaa tccgccgtta aacaaataat
     5341 gagggagctt tctcccttgc ttttctagag gagaaatacg aatgaacaca ggatatgtca
     5401 aattacatcg aaaagtgatg aattcattcg tttggaccaa tccttatatg tataaattat
     5461 ggaacttgtg tttgatgaaa gcgagtcatg agaatcgcaa gatacttttt aatggaaaag
     5521 agatacaagt gaacagcgga gaattcgtca cagggcgcga tgctatcaca tctgagatga
     5581 acgaaggcgt gaaacgtgaa catcaagtga acagcggttc tgtatggaga tggctaaaac
     5641 aatttgaaaa aaacggaatg ttgaacatca aatcaactac gaaatacagc gttatatcaa
     5701 taaaaaactg gtctttgtac caaagcagtg aacaacaaat gaacatcaaa cgcacaacaa
     5761 gtgaacaaca agtgcacaca aacaagaatg aaaagaatta taagaatgaa aagaataata
     5821 aaacatcatc gtcgcaacca cgcaaaaagc gtgtttacga caccgactca gtttactaca
     5881 ttctcgcgga ggagttattc aaacagattt gtcagaatca ggaaatcaaa aagccgaatc
     5941 tgcaaagttg ggcagatgac attcggaaaa tgatcgagat cgacaagcgg accgaaaacc
     6001 aggtacgggg aatgattgaa tggagtcagc acaatgtgtt ttgggcatcg aatattttat
     6061 ctgctaaaaa attgcgagaa aaatacgaca caatggcagc gcaagcaaat cgtgattata
     6121 aaacaaaaca aactaaaacg cttgaatacg agaaatttag cacagatgag ttgcctattt
     6181 gagaggaggc gtaggcatgg aaactgttgg ggaaatcatg gaaaagctga tacagaaagt
     6241 gcttgtccaa cgtggcgaat gtcctgaatg cggacagcct ttgtatggat ggcgtacgaa
     6301 gaaccctgat ggctcagaac gttgtaagcc aacctgtatg caatgtgggt ataaagcatt
     6361 gcgagttcag gaagacttac aaacagaacg aatttacaac gagagcctga aagcaagagc
     6421 aatcaatttt ttcaaaggtg gttctgttgt gcctaatcaa gcgttgtttg attgcacatt
     6481 gcagaattat caaattgtcg atcaagaaac aagacaagcg gttgaagtaa ccaaacgctt
     6541 tgttaattca gtcttgttag gaaatccaag tcaccttgtt ttaactggaa aacaaggaac
     6601 aggtaaaagt cacctagcga tggcagcggc ttgggaagtc ttgaagcgat caaactacga
     6661 taaaaaaatc ttatttatcg ggttacagga aatgctggat caaatcaaat tttcgtacaa
     6721 caatcctgaa ctcagaaaaa cgattgaggg atcgttgatt gcagatatca aaacagcgga
     6781 tttagtcatc attgatgata tcggttcaga actaggaaaa gatgcatcag atagtcgagc
     6841 gtttggcata aacacgctaa attcgttctt ggatgcacga cagaacctag caacgattat
     6901 cacaacgaac ttgcttggtg aagaactgaa aaaagcttac ggtacgagaa caatatcaag
     6961 aatgtttgtc aactctgatg gatttacgat ggtattttct caaacagcag acaagcgcat
     7021 aaaaccagtc aaaggagcga tcgcatgaat ttgactaaac aagaaaaaag aatctgtcgt
     7081 cagataatgt tgcaaattat aggtgatcgt gacatggacg aattatctca acaagagagt
     7141 cgaatggttc ggaagataag taagctaatt atttatcggg atacagaaag atttctcact
     7201 gttttaggta acgtctacga gaatccagag ttattggagg tagagtaatt gccaaaaata
     7261 ttagatgcat gttgcggtag tagattgttc tggtttgata agaacaattc tgacgtaaca
     7321 tttatggatt gtcgtcagca gtatgaagaa ttatcaacag gtcatgtgat caatgttgat
     7381 ccagatgtgg tcgcagactt tcgcgatatg ccttttgaag atgatgtgtt cgatatggtt
     7441 gtatttgacc cgccacactt aagacatgtc ggcgaaaact catggcttgc caaaaaatat
     7501 ggaaaattag acgaactttg gccagaagac atcaggcaag gttttgcaga gtgtatgcga
     7561 gttttacgac cttcaggaac attaattttt aagtggaacg aggaacagat accactttct
     7621 gatgtgttag aggctattgg agaacagcca ttgtttggta ataaacgaag caaaacacat
     7681 tggcttgtgt ttatgaaaaa attcagctaa cggaggaaac aaaggaggaa aagtaatgaa
     7741 gattgtatta aataaatgtt ttggtggctt tgggttgagc catgaagcaa aaatggaaat
     7801 ttttaaaaga aaaaatattg aagtattccc atacatcaat aactttagct atgactcaga
     7861 tgatgaatac acgagataca caggccaaaa gctaggttcg atggatttta tctactattt
     7921 caaaaaagac ccgaaaatcg acaaagttac aggaatttat agcgaaattg accgactgta
     7981 cggaattgct gatgattcca gtttttcaag tgattcaaac agaggtgata aggacctcgt
     8041 tgctgttgtc gaaaaactag gaagtgaggc cagtggacca tatgcaagtc ttaaagtcgt
     8101 tgatataccc gatggggctg agtgggaaat aagtgattat gacggcgttg aaactgcaca
     8161 ttatggtttt caaacaggta gtatttagtc cactaatgac aactaaagag gaggcagaag
     8221 gatgagtgaa gatgaatact ttgaacagta gtctattaac gacagagatt tttaactgga
     8281 aaggggtgta gtcatggacg catcggaagt agtaaataaa attaatagtc tcaaagaggt
     8341 tttcggagac gtcgaagtag tgataaacgc acaaggctat gacaacgaat tttttaagca
     8401 gattaccgac attagcattc agcaaggaat ggaagacgaa gacggaaact ttatcgatga
     8461 agtagccatt ttagtgactt gcgagtaagt aattgacagc taaagaggag gaagcggaat
     8521 gaaactaaaa gacggatttt actccagcgg ccacggcatc ggcggtttaa tgctagatat
     8581 gccgacaaag aatcctaaaa cacgtaagaa accaaaattc aaagtcggtg acatggttcg
     8641 ctgcgaagca gaaggattca tctatccatt tcgtggatat gtagaacacg tctataatca
     8701 ctcagcaatc attcgcattg aaaacacgat ggaatgtgat aagtggttag cgaaaagcaa
     8761 agagaattta gcagtggtga gattggtgga catggaagtt ataaaatctt aattttgctt
     8821 ttttacaact atcctacaac aatgagcgtt attccacaac tggaaggaga agaggcaatt
     8881 gtgaacattt tagagaatat agatattaag caaacaagga aaaatgctag acgattacta
     8941 aaaagataca gaaatttaga acgtttggtc ggaccagtga aaatagactt ttccgtgatg
     9001 actgttacca aaaatttgaa attcacaatt gacagtcaaa acgaagaaat cattgaagcg
     9061 ataagtactc gagattcggt tatcgaagca ttaacacggc taagtagaat ccatttccag
     9121 gtactttatt atagttattg ttttcctaat aagatgtcaa tgtatcaaat aggagaaaaa
     9181 ttaggatatt ccgatagaac tatcgagaga atgaaggcag tagctttggt tgaatttgct
     9241 gaggcgtata aatcaggaga actcatttca cgtacaaaat aaaaaaagtc ggattcctcc
     9301 gactatgaat aatatttccg acataagtat tatatcataa ttgggggaat cagaggatgg
     9361 tacttttcga tgtaaagaaa tatgagacac caagcgcgaa agatgttgat atggaacgca
     9421 caaaacataa tgtcgctgtg tttctttcag catatctatc agctagatgt agagtagggc
     9481 aacatcgaga accaaaagtg acagcatctt attccttggt tccaccttct acagctgatc
     9541 atatatttga agcagaaaga atgctgatcg ataaagaaga agcacaggaa gaatttgagt
     9601 atctgcataa attgtttgtt cgaggctatt cagcgataca gcatccgcat aagcctgatg
     9661 tgactgaaag gcgcaagaag atattctatg atcgttatat caatggtctg cccatttatg
     9721 taactgctca aaggaataat actagcgaag aatcggttaa agtagaatca aacagaatta
     9781 tcatccaatt tgcttcatcg ttagaactgg ttgctttcaa gtagccagtt tttacacttt
     9841 ttataccctt ttattaccaa tttggtttcc attttatacc ttttttatac caatcactta
     9901 cctattcaac gttgtattat gatagtgtcg aaaaattagg aaacaggatc gacaaaataa
     9961 aatgtaaggg aggaaatctc cctcatcgtt taattaagct tcgataggca gcaacggaaa
    10021 tattaagaat aaggatgtga atttcaactc cttctaaatt gttcttatta tctatcatcc
    10081 gttgctgtct attgtttttt taattattca cacgataact aaaggtaagt gaagagaaat
    10141 gattccatta ataatttcaa tttttgcgct ttgtcttaat gtatatatga ttggatttaa
    10201 aaatgggcaa aataaaaaat agtagcagcc aagaataatt ttatagtgtc actgtggcgg
    10261 aaagggtaga cgctaagcat gtgtgctagg tcaatgcttc ggcaaccatg caaggttcga
    10321 ttccttgcca gtgactttgg caaccgaggc atcggcggtt taaaaatata ggggtgcgca
    10381 atttcgtacg cgttttgtgc atcgtgtagg ttgctattac ataactggtt aggttagatt
    10441 gagatttggg attcggtaca aatgaatcgt caaatgtctc aagcacagga tcggaaacgt
    10501 ccctgcctgt gcattacata ttagatcact ctttgagtgg tctttttctt tacataaagg
    10561 aggctacata atgagaaact actggtatgt atcgctaact aatgaatatc ctcgaaccat
    10621 tgatgattgt tcagtgcgtg ttgtgcgttc tgtacaaatc aaagggaagt actctattgt
    10681 cgaaatgggg agagaagcag aaccatgtga gattgatgcg tgcaagctcg tttattgcgg
    10741 tcatggtttc tatgatgaac caaacattca aaataatatt aacaagaatt tgagggatta
    10801 gaatgcaaga aatggcttaa aaatctccaa tcaggacaaa tcaagttaga caaagtttcc
    10861 gatttaaaga tattgattga agctgattta atgctaaaag atattgaaaa ttagaaaaca
    10921 aaactcaacc taaacagaat gtgaggtggt gtgtattgaa tggcaagaca acgtgatcca
    10981 agacgtgatg aagccaaaag aatttggtta gaatccaacg gagaaaagca gttaaaggaa
    11041 attgcatctg aattaaatgt ttcagattct caggttagaa aatggaaatc gcaagacaaa
    11101 tggagcgctg aattgattag taacgttacc aatggcaaaa gtaacgttac taatcaaggt
    11161 ggcgctccta ttggtaatca aaatgctaaa ggtaacaaag gaaatagccg agcttctccg
    11221 ccagtgggta ataaaaacgc tttgaaaaca ggtgagtatg aaacaatatt ttttgacacg
    11281 ttaaccgata atgagaagga catctattct agtttgaatg atgatccttc ttttgctttg
    11341 tccgaagaaa tacgacttct taaaataaga caacttcgaa tgatgaaaag aatccaacaa
    11401 gctgaagctg gactaaatga tgaagaagtc gaacgattgc agcagctaag aaagattaaa
    11461 actccgattg aaaaaaatgg taaaaagcta gaaatcaagc gtgaggttat gcaagatgtg
    11521 cagattagca gaaaaaaaca tcgcaaaatt gatgatattc tttcaattga agattcattg
    11581 actcggatta gcaaccagtt agctaaagcc atcaagcaaa tgaatgaact ttatatgaat
    11641 gaatacagaa ctgatttaat taaagctcag actgataaga tccaagctga gacaaatgaa
    11701 attggcggaa ataattcagg tgaagaaata gaagaatgga aacaggcagt tttaaatgcc
    11761 gcaaacaaac gggcggtgaa agaaaatgaa taatgaattt attccttttg ctgatattgg
    11821 ttctgccatt gattattact atgataaacc agtagctttt tgccaagata ttttgcattt
    11881 gaatcctgat gaatggcaag aaaatgtttt aaatgattta gctgaatttt caaaggtttc
    11941 tgttcgttct ggtcaaggag ttggaaaaac agcattagaa gcaggagcaa tactttggtt
    12001 cttaacgtgt cgaccctacg ctaaagtaat agcaacagct ccgacaatga agcaacttta
    12061 cgatgtactt tgggcagagg tagctaaatg gttaaatgat agcttgatca aaaacttact
    12121 gaagtggaca aagaccaaaa tttatatggt tggtgattca gagcgttggt ttgctacggc
    12181 tagaacagcg actaaaccag aaagtatgca aggttttcac gaggaccata tgttgattgt
    12241 ggtagatgaa gcttctggtg tgtctgatcc aattatggaa gctattcttg gtacgctatc
    12301 aggttttgat aataagctgt tgatgtgtgg aaaccccaat aatattgaag gtgtctttta
    12361 tgattcccat aattcagacc gtgataaata cagagttcat aaagtatcaa gctatgatag
    12421 taaacgtaca aacaaagaca atatagaaat gattcttaaa aaatatggaa aagaaagtga
    12481 tgttgctcgt gtccgtattt ttggagaatt tccgaaaggt gcgttggatt catttatcag
    12541 tcttgaaaca gttgaattgg ctacagaaaa acaaattagt gattctttag tcaataaaac
    12601 aaaggttgct catattggtg tcgacgtagc tcgatatggt gatgattcta cgattctctt
    12661 tcctagaatt gctaccaggg cattggagta tgagaagtat tcaaaacgta gcaccatgga
    12721 aacaacagga tatgtcatca acatggccaa gaatctaatg agtcaatatc cgagtattga
    12781 taaagtgatg attaaagtcg atgacactgg tgtcggaggt ggtgtaaccg accgcctaga
    12841 agaacttata gaagacaaac attatccttt tgaggtgttt ggagtgaata acggttcaac
    12901 atcagaagac gatttttacg ataatttagg tactcaacta tggggaaaca tcaaggaaat
    12961 gttagaagaa aatatgacag caaatcttaa cggagaacag cctgttattg aattgccttc
    13021 tgatagttcg ttaatcaaag aattaagtac tcgcaaattc aaaatgacaa gtagaagtcg
    13081 tatacgttta gaaagtaaag atgatatgaa aaagcgaaat attggtagtc ccgatattgc
    13141 tgacgcactg gctttagcgt tttatgagcc accaagtcac tatcaattta ttcaatttta
    13201 ggaggtgagc ttttgattag tacagtatta tctttagaga gatataagaa gctacgtgtt
    13261 aaatatgcaa cacaaattga agatggaatg tttgatccga atggttttat agaagatatg
    13321 aaaccatttt ttgctgatcg cgaaagaaaa tatctagctt atactagcga aaagaatgaa
    13381 atagataata gaccaaagcc taacactgat attgtaaaag ttaataataa acttcatgct
    13441 ggtatgtatt caattgtcgt agaccaagca gtcaatcatt ttactggtat acctatcaaa
    13501 tgggattacg atgtatcgga acaaaaaaga acactcattc aaagattaaa agataaattc
    13561 ttaaaaaatg atatagaact tccgacagtt ccagaagctt ttaacaaatt aacaagcaat
    13621 cttgattcca tgagattcgc aatgcttgat tctgaaactg caacttttca aggagcttgt
    13681 ggagtagctt tccgattgct agagcctgtg gaagaagatg atggttggaa gttaagagca
    13741 agtaatattg aaccttggag agcagaaaga tatggaaatg ccggaatcta tatcaaagaa
    13801 aagtatgact cttaccagaa aaaatttttt caagaaatga aagttatgac aagaaataaa
    13861 attctgacat atgcttgcta tggtgatttg aattttgtta caagcggaac gttcaaaaaa
    13921 attgatgaga ccgataaccc tttggggacg attaccttgg cagaatttaa aaataatacg
    13981 aatcgttatt gtgattttga agtagctgag gaaattggag atgcaattga tcgtgctttg
    14041 tctgatcaac aaaacgaaat cgaacaattt aagcttgcgt acatgcttgt tactggcaca
    14101 acaatgagca aaggcactgc taaagaaatg atgaatcagc tagggattat caacttaaaa
    14161 gcccctactg caaaagctga atatgtcaca aaaaatttag caaaagattt caatgaatat
    14221 catatggatc tattgaaaaa acagttttac accatttgta aagcaatcga ttttaacgat
    14281 gaggtgttta aatcaaacag ttctggagaa gctcgcaagt ggcaaatcat tagcctagaa
    14341 gcgaaaacaa atactaaaga gcaatatttt agagaaggat tgaaagaatg cgcagaaaca
    14401 attgctgctt ttcttaagtt tcatgacaaa gtagaaattg agcctgaaaa aattattttt
    14461 actttctcta gatctttgcc aactgattta agttatttag ctgaagcttt acctaaactt
    14521 gcaccatacg tatccaaacg aactattcag agccaaattc catttgtaac agatgttgat
    14581 tatgaaaatg aaatgatgga attggaaagt ggaagtgctt atccagatag tgaatacaat
    14641 tttggcggag gtggcaatag tgacgataga aacgaagtat tggaccaaac gtcgagaact
    14701 ggaggatcaa gcaaggctca aacaagaaaa tcagacactt aaaaaattaa ctagtgtatt
    14761 tcctgaagca ctgaaagaga tacaagcaaa actattatca caagctgact tacacaatat
    14821 cacttatcca gaaatgatgg agttttacag tacaagtaat cagaaaaaat atcgtgaata
    14881 tgtggaaaaa aattataagt cattaaaaat gtatgatgca aaatacaaag agtttatcga
    14941 tgaatttttt ccaccatttg actatgcaaa agtcaatcgc ttattacaaa tacgatcaga
    15001 tgtatttaaa attcttgcag aatatgcgat ggatgcagat gtgaatcaat atttttctga
    15061 tcgcttagag gaaattcttc aaagaacata ttcttctaat gctaatgttt ttgttcaact
    15121 tttaaacgtt gatataccaa attatttacc agaaaatgaa attaaacatt atttgaacta
    15181 tccatggtca ggaaagacat tttcaagaag actttgggga aatatttcat cgcttgaaca
    15241 gaaactctct aatgctattg taaaaagtgt tgctagtgga gaaggcgtta tacacgcatt
    15301 aaacaccatg agattagact cagaaatttg tgacatgttt aagttagaag aatcaaagta
    15361 taacaaagcg atagaaaatc tcgttcgaac ggagtatgca aaatttgcac aagatggtat
    15421 tgaaaaatca tatttagaaa caggtattga ggaatacaac gtattgactg caaaagatga
    15481 gagagtttgc cggatttgtg gaggaaaggc aagtaagaat ccctataaac tgaaagatgc
    15541 tgtcataggt gaaaatcgag cacctttcca tagtcgttgt agatgtacgg atgttcctaa
    15601 tttaccaaaa ttaggaaagg atattgatga agaatatgac cgtttatttg gcgatttatt
    15661 agatgagttt gcacatgatt cttttggaat taatttgaaa cggaggaagt agaatgaaag
    15721 atttttttga agcagtacta acaattaatg taaatgctga tattgcagaa gcctacaaaa
    15781 cagctattga gtctgagaac catcctaatg gcttgagaga ccattggaat ggcaattatg
    15841 cctacgtggt tattggcgat caaactgtta attatcaaga taatactcca gttgataaga
    15901 ataccgttaa tttaacgatt caattattat ctcattcatt accaaattta aaagaaacag
    15961 ttgattggta tgaaaagatg ggatgtattg ttgttagaac tgactacaaa gaaggaaagt
    16021 ctagtaatta ggctttttta ttttgtccga aatgacgtta aactagcgca atactgggct
    16081 tggttgaatg gtggggcgca actattaaaa ctcaaagcaa tgcggggcgt gaaaacgaat
    16141 cgtggggcga aaggagaatg agcatgaaac acaaatcatt aatgccaatg aatttgcaat
    16201 actttgccga aggtgacgat caaaagtttt cttttgatga cttcaaatct tttgtggaat
    16261 ccaatgaaga agctcaaaaa tttattcagt cacaatctca aagtgttgcc gacaaacaat
    16321 tggaagcttg gaaacaaaat aacttagata aaattaaaca ggataccatc aaggaatatg
    16381 aggaatctaa gaaaaacaag tcacctgagc aaattcaact ggaaaaacta caagctgaat
    16441 ttgaagcaga aaaagcgttg cgtgtgacaa gtgataataa agcatttgtt gcagaacaaa
    16501 ttgctggatt agaactagat ggagagttaa aagagtctat ttctcaattt atgctaaata
    16561 atcttgttag ttcggataca gatttcacta agaatgctgt tgaaggtttt acaagtgttt
    16621 tgaatgcaat taatgagaaa catgcagatg cattaaaaga actacaaatg aagtctgcat
    16681 ttggtggaac tcaacaatcg aataaccagg ttcagcagaa caatgaaaca ttaacaaatc
    16741 cagaagaaca attaggacaa attcttcaac aatttaacta ggagagtgaa aaattatgaa
    16801 aaaaacatct ttaaataatt tagagtattt ggatatttca ccagcgatta atgctatgca
    16861 agtaccaaat acaccttttt taagctattt acttggtgct ggaaaaacag agccagcaaa
    16921 ctcgacagaa attaaatggc gtgaatatga tatcaacaac gatgattctt ctgaaaaact
    16981 tgagggcgga gaatatccag atgctgaatc aggtcgaact tggtttaaca actatactga
    17041 aatttttaga aaatcaacct ctgtatctgg tacattagat gctattaatg tgaatggagt
    17101 cggaaatgaa ttaactaatc aagtagcact acgtggtatg gaaatgaaaa ttgatttgaa
    17161 ccgaaaattg attactggtg taaaagctga tgaaaatggt tctaaaggtc gtcgaatgaa
    17221 tgggattttg aacttgatca attcagcaaa taaggcagaa acagccactg cgggtgcagt
    17281 aacaagaaaa gatatcgata ctttatttaa attgatgtat gaaaaaggtt atatgggaga
    17341 aaaactatgc ttgatttctc cagatatgca ggagttaatg actgatgagt tagatggaaa
    17401 atcaacaaaa attgttcagt tcggggaaag agtaactttt ggattgcaaa ttggaaatat
    17461 cgtgtctaat tacggtacag gtattgctct actagaacca tcattgccaa aaggaacaat
    17521 tgccgcaatc gatactaatt atgtgaaact acgtccatta cgtgaatgga gagcagaaga
    17581 acttgcaaaa acaacggatt ctagacgtat cggtcttgta ggtgaatact ctcttgaata
    17641 caatgcttca aactctgggg caattttaaa tttaaagtct gaataaaagg gagttagtac
    17701 tccctttttt gataggagga attacagtgg taaaaaaaga tgaaactaaa aaagatgaag
    17761 tcgtgaaata tagagtaggt aaaactaaaa attttgttgg gtttgttcat cctaaaactc
    17821 gtagatttat cacagcagat tcaaataacg aatttatcat ttctatagat gataaagaag
    17881 caattgcaat tttggaagat gcaattgatg ttaatgaaat ttaggaagtg atctgatgga
    17941 tgaatcgcta aaaacggaaa tcattgagtc tacaaaagaa gattttccag atttgagtga
    18001 agaacgcata actaatttat tagaaataat tttgctagaa attgaatcat acaacacttg
    18061 taaaaatgat atttcatggg aaaagttaaa aagcgtgatt agtgaagtgt tgtataaaat
    18121 aataaaaaat gaatcagaaa aaacagtatc ttcagttaga cgtggcgata caacgattag
    18181 ttatgcttca acaacaaatg atgttagtga gttacttcta ggctatggtg atttgatacg
    18241 aagagttatt ggttgtggag gattggagtt tttttaatga atgaagcaga tattttagaa
    18301 actacttatg aagatagttg tattattgaa agactgacgg acattgaaga ttctaataca
    18361 aatattacta ttcaagatta caaaaaagta tatgataatc ctatttcttg cgctctttca
    18421 caaggtcaaa tcgatggact agcagtcata gaagatggag agatggtaaa tgtttcaact
    18481 gacacatata aattatttgt tcatcctaag attaaactaa aaaaaggaga tcgaataaca
    18541 ataactcaaa aggccagtgg cttaattttt tctctatttg ctactaagcc tttttactat
    18601 cctagtcatt gtgaagtgaa tttgatagga agtgagaaaa atgggtaatc tcaaatatga
    18661 atcaaatgca gaaaagatca ttgagaattt taaaaatatg actgtaattg ctcaaaaaga
    18721 aggaatatcc ttcgttaacg attcaatgaa taaagtcgtt agtttagcta aaccattaac
    18781 tcctgtaaaa tcaggtaatt taaggcgagg atatcgtgta gtaaaagcta gaaaactatc
    18841 aagcggtcga attgttggag aagttataaa caatgaacat tattttaaat atgtagaaga
    18901 aggtcatagg actaaaaatg gtggctttgt caaagggaaa ttcatgttaa ctcgtgcaac
    18961 gaatcttgca aatatgtctt atattcctcg aagatttaaa caaatggcaa taaaaatcgt
    19021 taagaaagga aagtaacatg aaagatgaaa tcattgctgc aatcagtagc aaattaaaag
    19081 aaatctatcc tgatgggaca atatatcttg attcagttat gcagtcaact aaagattttt
    19141 atttcgtttt atcagtaatg gaatctggaa ctgaaaatgt aggaattgat attcaaaatg
    19201 tttctttctt aattgatatt gcattgattg ataataaccc taatagaaat ttaattaatg
    19261 aattagtctc acgttgtggg acttttttta atacgattac aatcgatgag caaatattat
    19321 ttccaaaagc ctatttacct gatgaagcag atggtgttca acatattcgt tttacattag
    19381 aatttccaca atatattgaa tggagtgaaa gataaatggg agaaaaaaga agtaaaaccg
    19441 gaattatttc tgtcgaaaaa cctacttggt ttcctttgga agatgagaca gggaattttc
    19501 cggtatatgg tactgcgttg ccaatgggaa cagcagtaag tatcaaacca acagctaatt
    19561 atgaaacaac acaagattat ggggattcag tggttcaaga tcaatttaca gcttttggtg
    19621 gtgcagaagt tgaactggaa gcaaatggat atactcataa agttttatct acaattactg
    19681 gagggaaaat tgttaaaggt ggtgccttgc gttctggaga agatattgcg caagatggtg
    19741 cgtttgcata tagacgtaaa aaatcgaatg ggaaataccg ttatacggtc ttttataaag
    19801 gacagtttgc tctagattca gatgaaacat caacgattga aggaagtaaa gtaagtttta
    19861 ctcatccaac ttggaagggt tcatttgtag atgtaccagg acttggatat atgtattcag
    19921 ttgatgaaga tgatgaaggc gtggataaag caatgatcgg aaattggttt acaaaagtag
    19981 caattccaat tgaagaagca gaactttcag gaggtacaga ataatgtcaa aatatcaaac
    20041 aacgattaaa ttaacgaaaa aagacgaaga aggtaaatat gagcaagtac aatttaaatc
    20101 tgctgaattt ttaccaggaa cagttgtaga agatgctgca ggagttatgg aagaaatgca
    20161 aacagcgact gataagcaat cagttaaaaa agctttaagt cgtgcttatt catttattgc
    20221 agatacttta tttgagggac aatttactgg tgaagattat tgcaaaggaa ttgatgctcg
    20281 tgagattgcc tcattgacag gaaaattatt gaagtctgtt actgcaggtt ttgatgaaac
    20341 ttatacagag acgaaaaaaa agtaagtgag gcgctcaagt caccttcatt taagtattcg
    20401 attacttacc gagaattaga tataaagacg caattactcg aagcaggttg gacgttacca
    20461 gaaattgaac gtactgactt ggatgagtta atgcgtcttt ttgcttttag agatgcggta
    20521 aaagagcatg aagatgttga gtactatgat aatttcactc aattttagga ggtgatactt
    20581 tgaataacga tgacctaatt ctgaagatga tactagatga atctggtttt actgccggta
    20641 tgaataatgc tgtcaaaaag ttgaactctt ttgatgaaac aatcgaaaga aaaagtagaa
    20701 atagtggcag ttcattaggt agtatttgga aaatatttgc tggaagtttt ctagctagcg
    20761 gagtaactag aatcgtagga gctggctttg atctaatcaa gggttccata agtggagcgg
    20821 ttgatcgagt agatacgatg aataacgctc tacgaaattt ccaaaatatg ggatttagta
    20881 attcagaaat tatgaagaat atcggaaaga atgggctttt atctcaaggt attcaaggac
    20941 ttcctactgc tttgaatgat gcgataagtc atgttcaact tcttgcttct tctacaggtg
    21001 atttaactcg ttcaactcaa atatttaaag ctttaaatga tggaattctt ggtttcggtg
    21061 gttcaactga tcaagttaat gaagctgtta ttcaattatc tcaaagtttc tcaaacggaa
    21121 aagtagacgc acaaacttgg aactcaatga tcaacgctca acttggacct actctttctg
    21181 ctattgctaa aaagatggga attacaatgg gagatctgaa agaaggttta tctcaaggta
    21241 agatttctgt tgaagaattc caaaatcaat taatagaaat ggataccaaa ggtggcggag
    21301 gacttaaatc attaagtcaa atcgctaaag attctactaa gggaattaaa acctctatac
    21361 aaaatgcaaa aacagctgtt acacgtggtg ttggtgaggt aatagaagga ttaaataaag
    21421 cattagtaga ttcagattta ggtggattta agggaattat tgataaagtg ggcagttcaa
    21481 tggaatcgtt cttaaaagta attgctgcaa atattcctac agcagtatca tttttaagta
    21541 atttatttaa cgaaattcaa aaatttggtt ctgctttgaa attcatgatg ccctttcttg
    21601 ttcctgcagc taccgctttt ggagcgttca tgtttcaact taaaggtata ccagcaataa
    21661 taaaaagctt caataatttt aagaatgcca taattggcgt tggaaattca ttaaagatta
    21721 tgggggcaat agctgctgct aatccatttg ttttaattat tggtgcagtc gttggtgcaa
    21781 tagctgtttt cggttacttt atggcaacca atgaagagct tagaaacaag gttatatcta
    21841 tttggaatga tgtgaaagat tccgtaattg gtgtattaaa aaatataaag gactggggaa
    21901 ttgatacttg gaattctgct aaagaaatgg catcaaatgc agttgagggt gtcaaagatg
    21961 cttggtcagg aacaaaggaa tggttttcta acacctggaa aggtattaag gatggggcca
    22021 caggtttatt tgataaaaca gtagagactt caagaaatgc agtcgatagt gtaaaaaatg
    22081 catggtctaa tatgaagaaa tggttttctg atacttggca aagtataaaa gattcagcca
    22141 gagaaaaatg gaatggaatc aaaggttcta ttatgtcagt tgctggtcca ttgattacag
    22201 gtataaagaa tgcattttta catgttactt tttatctaga gaccttatgg aataatttag
    22261 ttgagattgg taaaaacgtc tttgagattt taaaaaatgt tatacttgcg ccggttttgt
    22321 ttattacctc catgatttct ggtggatggg aagaaacaaa aaataatatg attgctgttt
    22381 ggaataatat taaagaaagt gccataaata tttgggaatc tataaagaat atatttgtaa
    22441 gttattttac aaatatttat tttgctgcac tcaatatttg gacagggttc aagcttacat
    22501 tgataaatat ttggaatgaa gtggtaaatc aagctaaatc gatttggtta aacataaagt
    22561 atttttttat taatctttgg attgatataa aatattttgc aattcagaaa tggattgaat
    22621 tgaagttttc tattattcaa acttggatcg atttaaaata taatgccatt actacttgga
    22681 ataatattaa acagtttttc aaagatactt ggaaaaatat taaagatacg gcatacaata
    22741 cgtggatttc tataaaaaat accatgatta atacatggaa taacattaag gactctttct
    22801 ggaatattgt tactggaatt gttaattctg ctgaaaatgc atggacaaat ctaaaaaatg
    22861 gtgtttcaaa tgctattaat cgggtaaaag aaatctttaa ttcgttaagg gaagtcaatt
    22921 tatttgaaat tggcaagaac atcattgatg gacttataaa tggtgtaaaa gaaaagtgga
    22981 atgctttgaa agatactatc aaaggtattg caggtaatat caaaaattgg attaaaggag
    23041 ctttagatat tcattctcca tcaagatgga tgcgtgatat ggttggtaaa aatattgttc
    23101 aaggtattat cgttggtatt gataaagagc aaagtaagtt agatcaaacc atgacaaatt
    23161 tagtaaaaac accgtctgtt caacctgtag taaatggaat aagtcaccta ccaattacac
    23221 aaacaaagca aaatatatct gctagtgaaa caaaagaaat tcatttacat ttaaatgttt
    23281 atggagattt acctgattca atggttcgga agattaccac aaaaattaaa acagaattga
    23341 caagacaaat gaaacgagat gctggtgcag taggaggaac attatatgca acttaagaga
    23401 ggacaatttt ttattaatca acattattct tctgaattta atgtgtatat tcaaaacagg
    23461 cctgcttctg tttcagctag tcgagtaatt gaattgagag agcgagaagg aaatgattct
    23521 atcattattg ataaaggcta ttacaaaaat gtgactagaa agattgagtg ttactataaa
    23581 gcaccttcaa ttgatatggt gcaggagtgg gaagatcgaa tcactgaatg gttagatatg
    23641 tcgtcttata gtgattttat tctttactat gatgaacaat atatttatca agctgtagta
    23701 atagaaggac ctgaatttaa aggaacaaga aaaacaggaa atattgtccc ttttgaattt
    23761 acagtgagta ttcgaccatt taaggaaaat tacaatggta gatttactat tcgacaaaca
    23821 gaaacttttg aaatttataa cccagagaag tattcttcaa aaccgcttat taaattgagt
    23881 ggttctggag atgcttcttt ttatattaat aaggataaat atgatttgaa atcgttggac
    23941 agagaattat ttatagattc taaattagaa gaggcttatc gaaaattaga tggtaattta
    24001 gaacatcagg atcaggtcac cttattttta gattttccat ttttatatcc tggaaaaaat
    24061 gaaattaaat ggacgaaaaa tattcattca tttgaaataa tgcctaggtg gtggagaaaa
    24121 gtatgaaacc aagaatatat agtcctactg aaacagattt ctcaacgaat ggcttaggaa
    24181 ttttaaagga ttgtacaaga tgtggaatat atgaagtagc taatggaaaa tatgaattag
    24241 agttggatta tcctttagga actagatttg atgaatattt tgaaaatgac tatcaaataa
    24301 aagcaaagcc aaacgatcaa gaagagtatc atatcttttt tattgatgat aaagatatag
    24361 atactttttt aaatacagta actatttatg ctcagagtcg tacaaatcga cttggaagac
    24421 gggtagtcac tcttgtggaa gtggactcta aaactggtca agaagcgata tcaattattg
    24481 aaactaaaat ggataaaaaa tctgacatac gactttattc tgatattacg gctgtttcta
    24541 gcacaatctt tgaagcgaga aatgttttaa attgtattgc tggtgaacaa ggatcattgc
    24601 ttcaatattg gggcggagaa attaaacgtg aaccatttaa gctttctttg ttaaagcgaa
    24661 gaggtcgcaa taatgttgga acgattcggt atggaaaaga tatgtctggt ttgaaggtca
    24721 aattagattg gacaggtata aaaacaagaa ttattccata tgctgatcct caaagtgaag
    24781 taggtacgac taatcgaatt tatggttcgc cagtagatag tgcctatatt aataactatc
    24841 ctgatgtcta tacagaacat gttcagttta cagaagaaca aggagtaaaa gacattaaga
    24901 gcttaaataa aatagctaaa aattacttta aaacgatcaa tcctggctgt gataagccta
    24961 aagtttctat tacggttgaa tttgataagt tgactgatag tgaagaagcg aaagaatttg
    25021 cgaagattag aaattatggt ctgtttgata catttaaaat atatcataaa aaatataata
    25081 tttatcttga atcaaaggtt agtggactac aatacgattc tttatctgaa aaaactttga
    25141 aattagaagc aggagacatt caagttgctt tttatcagca acaagctgta actattcagg
    25201 ataaattaaa agattatgca acgaataatt atatgagtga ttttaatgat tatgtttctt
    25261 caatgattac aggtcaaggc agtgcaggag gatatgtagt tttatggcca aaagaaaaac
    25321 cttccaacat ctttattatg gataatccag atttagaaaa ggcaagagaa gtactaagaa
    25381 tgaataaaaa tgggattgct ttttctaaga aaggatggcg ggggcctttt aattcagctt
    25441 ggacattaga tagtatattt aatgccaatt ttatacaaac tggattaatc aaagcagata
    25501 tctttcaaaa ttcttttaac aagactggag atgtattgaa attagttaat ggactactcc
    25561 aaatttggaa caacaaaaag aaaataatgg agttaactaa aaaaggaatg gaattttgga
    25621 attctaaggg ttcaattgga acgattggaa caactgattc tgttggtaat ccttttcctg
    25681 gggcttctac tccaacccct attgaagata attctttagt tattcgtaca aatggagacg
    25741 gcaaatatat tttgatttct cctaaagtag gaaaaggatt agttttatta ggaaatggta
    25801 aagcaattta ttttggagac ttagatgtac aaggaaaact tacagttaaa ggaaaagaaa
    25861 taattcctgg acaaggtggt ggtccatcgg gaggtggaga atctactggt gggtatccta
    25921 gtgaattaaa aacagatgca gaaaagagag cttggagaat ttacgatatt ttgtgtaata
    25981 acggatttac gaaacaatct gcatgtggaa tattggggaa cattcaacaa gaaacaggag
    26041 gaacttttga tcctgatact gttcaaatag gtggaccagc atacggatta gttcagtggg
    26101 atggttcttc atatcctctt gttggtccag caacatggga tggaaaagtt tatgttcaaa
    26161 acttatttaa tgctgcaggt attaaagaac caataacgag cttagatgca caagttcgat
    26221 tgcttatttg gacatttaca aatggacaat ggatgggcgt agtacaacct acgacggttg
    26281 atggatttaa ggcctgtact gatccaagac aagcagcata tgcttttgaa cgaaactatg
    26341 aacgtccggc agcgacacat cctgaacgtc aagattatgc agttaactgg tataacaaat
    26401 ttaaagattt aaaaccagga ggagctactg gagaagcagg actaaaacat ttagagtctt
    26461 tgattggaca acgaattggc aatggtcagt gttatggctt gtctgcagaa tattcaggat
    26521 atctgggtgg ttgtggcatg ggtgctggaa caaaatatgg tttaactcat gtgataggaa
    26581 atacttctgc agcatctgat attggtattg cctatgattg gtctgctgtt ggttggaaag
    26641 tgattcaaaa ccctagatat gatcaattag tagttggtgc aattattaat tgggcaagag
    26701 gtggacaagt gggttcatgg tttgcagatg gaacttatgg acatactggc gttatccgag
    26761 gcttagctaa tggtcgtatg caaacttatg aacaaaacac agagttaggt atgatttgtg
    26821 gaaagttaga tcgccagtat tatagtgcaa gtgcaatttc ttccattgtc ataccaccaa
    26881 aatagggagg tgatttaatg gcaaagtgga atgtcatatt aagtacaaca gaaccctata
    26941 attacgtggg gatgattcaa gttcgacaag gcaataagaa tacagaggtt atggaagcga
    27001 ctatagttga aaatggtctt ccctacgatt tatcagaatg taaggtatat tttgaatcag
    27061 ttgtaggtgg gaaatatcca gtccaattag aaacaaaaat tgtggatgct aaaaaaggga
    27121 aaattaacta tatttttgat aaatattcca tgcagtgttt acatcgacaa acagccaatt
    27181 tcattatatt taaaggagaa gacttgattg gaacaactca agacttctct tattttgtca
    27241 ttaatgctgt ttcaaaaaca gaaggagaaa tgggttctta ttggcaatca atcgaagatt
    27301 taattgcgga tatgacggac tttattaatg aaaataaagg cgattttacg gactggatga
    27361 atgaaaggaa agaagaattt gaacgttgga gacaagaaca ggaacacagt ttccaagatt
    27421 ggagagaagg acaagaatca gactatttgg catggtttga atcaatcaag gatattttaa
    27481 agacgattga tccaggtgga gtcatgttag ccgaactaac ggatgcgcga gtagatattc
    27541 aaggagttcg tcatgcgtct atttcagagc gtttgctggc agatatggac tatttatatc
    27601 agaaattgcg agcaacgctt ttcacgattg aatacgggga gattgaagtg actgatattt
    27661 tgcaggatga tctcttttca gataatcatg aagtcgaaaa agttggaact gtagcattcc
    27721 cgattgaaga aggagccttg atcatcgcaa ccgttgatga tccaaagcaa aatgtgttca
    27781 ctcttgagaa agttggggtg atctaatggc taaaactaaa cgaatgatgg aaacggatga
    27841 aaaaacgggt gtacaacgcc aattctttcc aatcacacat gcttccgcag ttcttgggtt
    27901 agaagaaata atagcaggag aagcaacagt tttatctgtt aatggaaaaa ttggagccgt
    27961 cgtcattact aaagaagatt tgggattaga gaatgttctc acagaattac cctatgcaag
    28021 tgaagaagat gacggcatta tcacggcaga aatgtatcaa aaaattttaa acagtggaga
    28081 aggtgactac gtgttgccag ttgccactat cgaccgtttg ggtggcataa aagttggtga
    28141 attattgacg attgatgaga cagggaaagt ctctgcagtc agacaatctg atgtcaattt
    28201 ttcgctggag ttaaaagaaa aactcgattc actgaaaaat tatactgctg gagaaaacat
    28261 cactattgat gaagatggaa caattagttc tacaggtggt agtgggactg gtggtgtcaa
    28321 tcagtcatat gtagatcaaa aattccaaga agctgtaaat caagcagaaa attacacaaa
    28381 cgaaagaatt ccaaatttta cttttgaaaa aattggggag gtatagagaa tgacagatat
    28441 cgtaaaaata aaacaaagca atgtacaggt ttatccacaa actcattgga atgctataga
    28501 aggcaaacca acaacggtga agggagataa aggcgatcct ggccaagcag caacaattac
    28561 cataggaacc gtttctagtg gttcaaccgc ttctgttacg aatgtaggaa catcatctgc
    28621 agctagattt aattttgttt taccaaaggg agataaaggt gatcctggaa taaatgccac
    28681 aactacagct gtagctacaa ctacagcaaa tgggttgatg tcgtccacag ataaaactaa
    28741 gttggatgga attgcagctg gagcacagaa aaatccaggt aatgctacaa ctacgacagc
    28801 aggtttaatg tcagcaactg acaaagctaa actcgatgga ttagccaata ttacatttga
    28861 gaaagtgggg acggtttaat ggctgatatt gtgcaattaa aagaagacgg agttgctaaa
    28921 tacttaaaaa cgcatgtaga agctattgat ggtaaagaag cattggtgca gacagatgga
    28981 gaccaagcca ttgcaggaca taagaatttt tcaggttctg taacaatcaa taataaacgt
    29041 gttttgacga ctgatgataa cagatatgaa gtggtaaatc tggttgtcac taacggtaat
    29101 acagggacag caaagcttta tcgtgaagga aaaacagttt ctatatattt tgtggcttta
    29161 aacggaaaaa gtagtggcgg gaatgattcg gttattttaa ctgttccaga aggctatcgg
    29221 acaccaatta gttttgaaca actggttggg tcaatagacc gttctacttt gaacagtgct
    29281 caactatcta ttggcgcaga cggagccatt aaatggagaa gaaattcaag ttatggatca
    29341 gcttattcat ttgttatcac ttattcaatt taagggagga aatctaatga aagtagttta
    29401 caaatcaatc aagccttacg gattcgagca aatcattttg aacaatcaag aaaatatccc
    29461 tgaaaactgt acagagatta aaccaccagt tcctaactgg agaccaagat ttgattttga
    29521 taaaaaacag tgggttgagt tagctactga agaagagaaa aaagggaatg ctgttgatag
    29581 cgtagatgaa ttggctaata ttaaggcatt atacgaaacg ctgaaggcag aaaatgatga
    29641 attgaaacag ctaaattcta aagcaatgct aaacaatgta gcaatcaagc aagaaaatgt
    29701 cttattgaaa gaaaagtcag aaagtttagc gcagttgaat tcaaaaacga tgcttgcttc
    29761 tgtacaaaat accaaggaaa tcgaagaaat caaaaaacaa ttacaaggtg ggaagtaaca
    29821 tgtattcata tgaagatatc aaactaatgt atgactgggg ctgtttcact aacgaacaag
    29881 taatggtttt cgttccgttg tgcattactg aagaagaagc agataaaatc attagcaaag
    29941 aagagagcgc atcttaattg atgtgctttt tattttgatt caaggagttg tcacatgatt
    30001 aatttagggg aatggggagc gatagcagga tcaataaccg ctatcgtttc tttgatttta
    30061 ttagtaataa aaccaattac tgcatctttc tcgaagatta ctgagactct ttcaaaagta
    30121 agtcacaatt tagatttgct gactaaagat ttagaatcga gcaaatcaga tcgattgatg
    30181 attcatgaag aactaaagaa acacgatgaa agattagata cacatacaga aaaattggtg
    30241 gaacacacgc aacaaattaa aactttattt agggagagaa gaaaatgaat aataaaacgt
    30301 tcgaagtact aaaatggttc gcactggtaa ttattcccgc actagctact ttcgtggggt
    30361 tagttggtaa agcgctcaat tggcagtaca cagatatctg tgttgtcatc attactggtt
    30421 ttggcgcgtt tttagggagt gtgttgggtg tatcaaatcg aacctacaaa atgttctcgg
    30481 ctgaaagcga agaaggagga aacaaatgaa aaagaaaatt actattactg cgatgagcct
    30541 gttaacggct ctttttttat tacccattaa tacgtttgct tatactatta atgacgagta
    30601 taatttagcg ccgaatcaag gagactccag attagcaatt cctaacaaaa ttattttgca
    30661 cgaaactgga atagatgcac cagcaagaaa cgtagccgcc aacatgaaaa ataattataa
    30721 cggaagcaat tcttatacta cagatgttat tggtgacggt gggattgttt accgtgtggg
    30781 tgagcaagga tatgtttcgt ggggagctgg taacgctaat ccttatgcgc ctgtacagat
    30841 tgaattacag cgcacatatg ataaagcatt gtttgaaaaa aactatcgag cttatattga
    30901 atatacaaga gatagtgcaa aaaaatatgg aattccattg actcttgatc aaggaacttc
    30961 tttatttaca aaaggaatca tttctcattt gtgggtgaca aattatgttt gggggaacca
    31021 cacagatcca tatggttact tatcgcaaat gggagttagc aaagaaaagc ttgcttatga
    31081 tttagctcat ggatttaccg atgaaaatcc aacaacttct gaaaacaagc ctgtcattga
    31141 tccaacacga gctggtgcag ctaatcctac gctgacagat ggaacaaatc acgcccacat
    31201 tgatcagttt ggggaaatcg aaaacgcaaa cttgcatgtg gctggatggc acattgctaa
    31261 ctataaatac gagtatattt tcattatgga ctacaatact gggaaagaat tagctcgagt
    31321 aagagctgat ggaatttata gaccagatgt aaaccaagct tataatactt ctggaaatgt
    31381 tggttatcat gtatctttca atatgcgtaa ttttcctagt aagaaagtct atgtaatgat
    31441 gcgggcaacg aatgatccag a
//
LOCUS       DACGEU010000025        30841 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.025, whole genome shotgun sequence.
ACCESSION   DACGEU010000025 DACGEU010000000
VERSION     DACGEU010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30841)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30841)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30841
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.025"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            322..1191
                     /locus_tag="IXR40_001085"
     CDS             322..1191
                     /locus_tag="IXR40_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extradiol dioxygenase"
                     /protein_id="HAQ4360949.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            1400..2425
                     /locus_tag="IXR40_001086"
     CDS             1400..2425
                     /locus_tag="IXR40_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HAQ4360950.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            2464..3414
                     /gene="manA"
                     /locus_tag="IXR40_001087"
     CDS             2464..3414
                     /gene="manA"
                     /locus_tag="IXR40_001087"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HAQ4360951.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIASEPGK"
     gene            3508..5211
                     /locus_tag="IXR40_001088"
     CDS             3508..5211
                     /locus_tag="IXR40_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4360952.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKTSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            5213..7246
                     /locus_tag="IXR40_001089"
     CDS             5213..7246
                     /locus_tag="IXR40_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAQ4360953.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            7257..7697
                     /locus_tag="IXR40_001090"
     CDS             7257..7697
                     /locus_tag="IXR40_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAQ4360954.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAETIEEVQMIFEHGHI"
     gene            complement(7897..9024)
                     /locus_tag="IXR40_001091"
     CDS             complement(7897..9024)
                     /locus_tag="IXR40_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4360955.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLSLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLLDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(9027..9704)
                     /locus_tag="IXR40_001092"
     CDS             complement(9027..9704)
                     /locus_tag="IXR40_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4360956.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            9968..11734
                     /locus_tag="IXR40_001093"
     CDS             9968..11734
                     /locus_tag="IXR40_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HAQ4360957.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEAFATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            11749..12186
                     /locus_tag="IXR40_001094"
     CDS             11749..12186
                     /locus_tag="IXR40_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAQ4360958.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            12199..13350
                     /locus_tag="IXR40_001095"
     CDS             12199..13350
                     /locus_tag="IXR40_001095"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HAQ4360959.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(13412..14110)
                     /locus_tag="IXR40_001096"
     CDS             complement(13412..14110)
                     /locus_tag="IXR40_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobyric acid synthase"
                     /protein_id="HAQ4360960.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(14103..15455)
                     /locus_tag="IXR40_001097"
     CDS             complement(14103..15455)
                     /locus_tag="IXR40_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HAQ4360961.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(15678..17078)
                     /locus_tag="IXR40_001098"
     CDS             complement(15678..17078)
                     /locus_tag="IXR40_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HAQ4360962.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            17239..17976
                     /locus_tag="IXR40_001099"
     CDS             17239..17976
                     /locus_tag="IXR40_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HAQ4360963.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            18101..18580
                     /locus_tag="IXR40_001100"
     CDS             18101..18580
                     /locus_tag="IXR40_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HAQ4360964.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            18577..19344
                     /locus_tag="IXR40_001101"
     CDS             18577..19344
                     /locus_tag="IXR40_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360965.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            19574..20143
                     /gene="lepB"
                     /locus_tag="IXR40_001102"
     CDS             19574..20143
                     /gene="lepB"
                     /locus_tag="IXR40_001102"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HAQ4360966.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(20247..20849)
                     /locus_tag="IXR40_001103"
     CDS             complement(20247..20849)
                     /locus_tag="IXR40_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HAQ4360967.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            20955..21424
                     /locus_tag="IXR40_001104"
                     /pseudo
     CDS             20955..21424
                     /locus_tag="IXR40_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325408.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            21530..22114
                     /locus_tag="IXR40_001105"
     CDS             21530..22114
                     /locus_tag="IXR40_001105"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HAQ4360968.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            22117..23190
                     /gene="prfA"
                     /locus_tag="IXR40_001106"
     CDS             22117..23190
                     /gene="prfA"
                     /locus_tag="IXR40_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HAQ4360969.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            23183..24022
                     /gene="prmC"
                     /locus_tag="IXR40_001107"
     CDS             23183..24022
                     /gene="prmC"
                     /locus_tag="IXR40_001107"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HAQ4360970.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            24015..24194
                     /locus_tag="IXR40_001108"
     CDS             24015..24194
                     /locus_tag="IXR40_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360971.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            24216..25241
                     /locus_tag="IXR40_001109"
     CDS             24216..25241
                     /locus_tag="IXR40_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HAQ4360972.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            25432..26676
                     /locus_tag="IXR40_001110"
     CDS             25432..26676
                     /locus_tag="IXR40_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HAQ4360973.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            26829..27776
                     /locus_tag="IXR40_001111"
     CDS             26829..27776
                     /locus_tag="IXR40_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAQ4360974.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            27910..28539
                     /gene="upp"
                     /locus_tag="IXR40_001112"
     CDS             27910..28539
                     /gene="upp"
                     /locus_tag="IXR40_001112"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HAQ4360975.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(28678..28920)
                     /locus_tag="IXR40_001113"
     CDS             complement(28678..28920)
                     /locus_tag="IXR40_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4360976.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            29041..29113
                     /locus_tag="IXR40_001114"
     tRNA            29041..29113
                     /locus_tag="IXR40_001114"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:29074..29076,aa:Thr,seq:cgt)
     gene            complement(29232..29870)
                     /locus_tag="IXR40_001115"
     CDS             complement(29232..29870)
                     /locus_tag="IXR40_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HAQ4360977.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(29993..30625)
                     /locus_tag="IXR40_001116"
     CDS             complement(29993..30625)
                     /locus_tag="IXR40_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HAQ4360978.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
BASE COUNT        10498 a         5422 c         6210 g         8711 t
ORIGIN      
        1 cacaaaattt ttcttactac tcgaaactaa gcgacttttt cacaacctct tccttaaacg
       61 gtgttcaaaa gcttgcatct gcggtaataa gcccaaccaa acgaaaaata ggaggagcta
      121 tttttgtttg gctgttctta ttacttgatg cagaacagct ttttcacaac ctctttttat
      181 aagagttttt actcattaat ttacaaaaaa caagcaaaat gcgaattttc tcacattttt
      241 tttaacaaaa tcaaagttat tgcttgaaag aagaagaatc catcgttaaa ataaagcttg
      301 acgtagaggg gagcaagaaa tatgaaagat tttcaattgg gggctgccac ctatttaaaa
      361 agtgtagcca ttcgggtgaa agaccgagat aaaatgattg atttttacaa gaacgttgtt
      421 ggctttgatt tgaaaagaga agaaaacgaa ttagccattt taggaacaga agaagctgga
      481 agtgaaatgt tgctgctgga agaaagtcct agagcgaatg atcacatggg ggtgatcaaa
      541 aagctgaacc gtttttcatt gattatccct agcacagaag aaatggcaga tatcctttgt
      601 cgtatccgta aaatgaatta tccaatcaaa gaagctttag aagatcatgg acgtatgggg
      661 attttgctcg tagacccaga agagaatgaa ttggaaattt accatgaaga gaataagaac
      721 gaccaaagag aaattccaga aacaatggat caagaagcat tattaagaaa atctgaagaa
      781 aaattcagta aactatcaac aggttcttat tttgaaaaaa tccatttaaa tgttactaac
      841 ttaacaaaag aacgccaatt tcttaatcat gtacttggtt tgaaggtaca taatgaagaa
      901 gagggcatcc atgtattgaa tgaaggagat ttccatgttg gtttgacaga agctagcgga
      961 ggcgcaattg atttgcctac agatgaagtg attggacttg attttctgaa attcatgatc
     1021 gatactgaaa gcatggaagg actgattgct cacttgcagc aactatcagt tgatttcttc
     1081 ttagacaaaa agcacacagt actcacaatc tatgatgcta taggaatcga atggtggttc
     1141 gtcagtgagc caaaagaaaa gaataaaact gacattcgat gcgacgctta actttttctt
     1201 tcttaacgat tgtcgcatgt ctcgtcattt tatgaacggt catactatcg cttattctag
     1261 agatagaaag agaaaatagt ataccggggg aaactgcgcg gtttttcgcg cagttttttt
     1321 gtgtaaaaaa ggttgattcc tcatagatta agctttaagc ttggactgta agaatctgat
     1381 agaaaagcag gagaaaaaga tgtatccaca cacgaaacag cttattttga aaaagatgga
     1441 agaaggattt tatccaggtg tagcagtcgc cttcataaaa gaaaatcaag tagaaacatt
     1501 tacagccggc tttgcccaag tcgttcctga aaagcagctg atgacagaag atctgttgtt
     1561 tgatgcagcc tcactgacga aagtcgttgc aaccacttca ttagttttac gtctattaga
     1621 agatggaaag atagaactcg atcaaccgct tcataaatat cttcctgaat ttgaaaatca
     1681 gacaatcact ttgcgtcatt tactgacaca tacttctgat atcaaaacat ggataccaaa
     1741 cagagataag ctatctcagg aagaattgat cgccgcttat ttgaagctag aaccaggtga
     1801 gcaactagga aaagaagtaa aatatacaga tgccggtacg attcttcttg ggttgatgct
     1861 agaggaaatt taccaagaaa ctgcagtgga aatctttcaa gaacaagtat tggaaccatt
     1921 aggaatgatg aacagcttat ttcttccttt tccttccaaa aaaatcgttc ccacagaaca
     1981 actgccttcg ggtgaggttt tgcgtggaca aactcatgat ccgaaagcaa gagttttggc
     2041 tgaacatgca ggtaacgcgg gtctctttat tgatttgaaa gacagcatta cttttgtcca
     2101 aatgtatttg aacaagggaa aaatccgtaa tggtcgtttt ttagaagaag agacgattga
     2161 ttctttactg caagatcaaa caccgaaaaa aaatggctat cgttctttag gatgggactt
     2221 aaaaaaggat gtagaagacg gtcatgcgat tctttttcat actggttata caggtacgtt
     2281 tttcttgatt gatataaaaa cacaagaagc gttgatattt ttgtcaaatc gcgtacatcc
     2341 tgtcgatcat cgtgcggagt atctcatatg tcgagatgaa attgttgaaa actttttgaa
     2401 agagaaagcg gtattaccga aataatgcta taatagctat gaaaaatgag aggagtttga
     2461 attatgcagg aacctatgtt tttaaaacca gtttttcaag aaaaaatttg gggaggaagt
     2521 cgtttacgtt cagtctttgg ttttgatatc cctaacgata aaatcggaga agattgggcg
     2581 atcagtgcgc atcctcatgg tgtcagtgta gtagaaaatg gcgaattcaa agggaaaaga
     2641 ttagatgaac tatggtcaga acacaaggaa ttgtttggcc atccttcaga accagtgttt
     2701 ccattattga tcaagatctt agacgcagaa gatgatctat ctgtacaagt acatccagat
     2761 gatgcctatg ggatgaaaca tgaaggtgaa ttaggaaaaa ctgaatgctg gtatatcatc
     2821 gatgctgaac ctggtgcaga aatcatctat ggtcatcatg caaagacaag agaagaacta
     2881 gctgagatga tcaaagatgg gcgctgggat gaccttttga agaaagtacc agttaaaaaa
     2941 ggtgatttct tttatgtacc aagcggaacg atccatgcta ttggtaaagg aatcatgatt
     3001 ttagaaacac agcaaagttc tgacacgact taccgcgtgt atgactacga cagaaaagat
     3061 gcgcaaggac aaacaagaga gctgcatatc caacaatcga tcgatgtaac aactgtccct
     3121 gcgaaaacac cagaattaca aatcaaagaa gtccgaaaag ggaattcatc gatcgtcact
     3181 tatttagaaa ctgagttttt caatgtatat gagtgggata ttaaaggaat cacatctttc
     3241 aaaaaacaag ccccttatac attgatgacg gtaatcgaag gagcaggaga ccttgtcgtt
     3301 gacggaaaaa catatccatt agaaaaagga acaagctgta ttattccaaa tggcgtttct
     3361 gagtgggcgg tccaaggtga actagcaatc attgcgtctg aaccaggcaa atagttccca
     3421 gatagctgaa agcagcagac ggtttttcgt ttgctgcttt ttctacataa aatccgtcca
     3481 tcaataaata gaagtctggt gaaaaagatg gaatacaaat ggaaagcaaa caacagcagt
     3541 cgcgtgtcta tgaaacaact gagaaaagct ggacatcact taaatgaaat gatcatgcca
     3601 aatctaagtc tgtttatcgc ttggggaatc ttgtcattag caacaaaagg tgtgtctggc
     3661 gatttgcaca ccacattaga agaggtatgc cattggatga tccagctgct tttacccatc
     3721 ttgatcagtt attcaggcgg gaaatcggta gggggacaaa aaggggcagt cgccggtgca
     3781 attgcttctt tagggttgat cgctcgttcc aatgctccac aaatcgtagg agcgatgatt
     3841 atcgggccgc ttgccggcat cgtatatgaa caatttgttt ctagattcca tgtgaaattc
     3901 aaggctggat atgaaatgct tgtcagcaac ctactagtag gactgactgg tagcgttatt
     3961 tgtataattg gaatcgtttt tattgaacca gttttaaata gtgttcactt gttgctcgcc
     4021 tccgttgtgt cttggctagt cacaatgaat ctgttaccac ttgtcagtct gatcttagaa
     4081 cctctaaaag tactattttt caataatgca atcaatcatg gtgtattgac acctttagga
     4141 atcgaattct cacaaacagt cgggtactct tccttatttt tgatggaggc aaatcctgga
     4201 cctggtttag ggatcttact ttctatcctt tgttttgcag aaaaacagga aaaagtaaat
     4261 gcgagtggag cattgatgat ccatgcgatt ggcgggattc acgaaatcta ttttccattt
     4321 gtcttgctgc gaccgtatct atttttagct gtaatggctg gtggggcaag cggcacgttg
     4381 atatttcaat ggttagatac gggattagct gcacctgtat cgcctgggtc actactcgtg
     4441 atttttgcca atgcgcctta tccacaacta gctggggtaa gtatagggat agcaatcagt
     4501 acatttgtga ccttcatttg tgcagcgata ctattgaaat taccaaataa agaaaaagag
     4561 aacaaaacgg tcaaagaaag gggagaaatc ttggaaccat ctatcattca ttccgtcatt
     4621 tttgcttgcg actcaggtat gggatcaagt gctatgggag ccgccctgct gaaaaagaaa
     4681 ttagcagcag aaaaaatcga tctttctgtc ggatacagct ctatctatga attgaataac
     4741 caagtaaatc agctggttat cgtgcaacat gaactagcgg gtcttgcaag agaaaaagta
     4801 cctcaaagtc aaatctatgt actggatcac tttttggaaa cagatatctt gctgtcacga
     4861 ataaaagaag cgatccaatt tccaaagcgg gaagaaaaaa aagagatagc agatatcaca
     4921 gaacaaaaaa cgtcgcctgc taatattgta tttttgtata aaaacaacag acgcggctca
     4981 caaactatgg gcatgacgat tttaagtcaa ttagcaaaaa aagcgaaaaa acagtttgtt
     5041 atctcaaaag aatcaataga aaaaatcaaa atccaagaag aaacgattta tatcgcacaa
     5101 agagaactag ctgtaactga acagctagaa gaaaagatcc ctcggctagt tctagttgaa
     5161 cattgggtag ctacgaatga atacgaaaaa ctcgtgaagg gagaaatata agatgtattt
     5221 atcgcccaga gaaaaacaat tattagcaga atttctcagt agcccgtcac ctgtatctat
     5281 ccaaaaaatg atgaatttat tgaaggtcag taaacggact atttaccgcg aattagataa
     5341 tcttgaagtc tcattgaaat cggtaaatgc ttctttgaaa aaagcagcta gaggctcatt
     5401 tgtcattgag gcatcagaag aagtattaga gcaattaaaa gaaaatacag atgggaaaag
     5461 taatgactta tccactgcta aacgacaaca cgcgatttta gccgagttgt tactgacgac
     5521 agagccgttg agtcttgctc atttcatgga atcatatcgc atcagtaata ccacttttta
     5581 tgcagatatc aaacagttgg aagaaagtat tcgccaactg cctttggaaa tcattcggaa
     5641 ccagggatac gagatcgaag gaccggaaaa ataccgccgg cttctgacag cgaatgtatt
     5701 agaattagaa atcaatgaat atgaactttt tcatagtatt tctttcgatg catcactgaa
     5761 ttattttttt cgattcgttg atccgcaaca tctatctctt gcacgcaaag taatcgggga
     5821 agaattgatc caaaaaaaga ccaatctaag tgatagaaag cttgaacatt tggttttgat
     5881 gctgacattg acgatggagc gtgtgacgaa aaatcattta ctgacaaatg agacatataa
     5941 tagtctggca aacaaagaat tactacagac agctaaacga ttgttttcac ggatcgcttc
     6001 tgagacaaaa caactttatc cagtaaatga gatcgtcttt tttgcaggat tattaaatga
     6061 cttcacgaac tcatttgatc agaatttctt tgaagagacg ttcgatacac agcttgctta
     6121 tttagtaaaa caactgattc aagaagtaag tgaagagacg aatgtccatt tttatgaaga
     6181 tgaaactttg tacaaaatgc tgttgactca tttatctggt gtgttttcaa gagccgtttt
     6241 acaagaagag acactgacca atccgatttt agaaaaaatc atggttcaat acgaggaagt
     6301 tgcgaatgca atccgtaaag cagtagagcg gatttttcaa gaaaaaaaat tatccgaaga
     6361 agagatcgct tatatggtcc ttcattttgc gaattcattg gaacgaagtc cgaaagaaag
     6421 caatatcagt attgcaggat tttcgccaag tggattagct tctactagca tgttggaact
     6481 acgattgaaa aggtattttc ccttcatcca acaaattcat ttctatcgga ttgctgattt
     6541 aaaaaaaatc gatttacaag aagaatatga tgttgttatt tctacatcta ttttaccagg
     6601 atacggtgga aaatatattt tagtctcccc gctactgcta gaagatgaag tcaagcagct
     6661 aaaagaagct ttttcgcata ttgagaagaa aaaaaggcaa aaaattacgt ataacagcaa
     6721 taacgagtgg atgatagaag atacttatga ggaaacaatg catttcatgg atcaaatcaa
     6781 tcaattactc ggtcgttttt ttatccaaga actggataat cctgagacga tttccgaaac
     6841 gattcgcagc ttatttcctt attttcctga aggactagta acggatgaag aggtggttca
     6901 tcgccggctg cttaagcgat atgaacaagc acctatcggt attcctcata caaatatggg
     6961 gttattccat acatccagct cattgatttc taaaccgatc ttttgtattt tcaatttgaa
     7021 acatccgttg accattgaag ggatggatag acagccagtc gatttgtccc gtatgttagt
     7081 tatgctggcg ccttcgccaa tccaagaaaa agacgggatt cttttaggaa agatcagtgg
     7141 agcaatcatc atgaatgact tgaacaccga gatcttccgc tcaggaaata aagaaatcgt
     7201 ttatcagttg ttagcgaaaa tcctgattga agaaataaag aaatgaaggt gaaaagatga
     7261 tacagctacc agcagaaaaa atattgctcg atcaatccta tcaaaattgg aaagaagcgt
     7321 tgaccgagat cggccagtgg atgacccaac aagggggaat caaaccggca tatatccaat
     7381 caatgatcga aagacaagaa aaagcgagtg tctatatcgg gaatttcgta gccttgccac
     7441 atgggactga caaagatgaa gaagtagtag aagaaggaat ctatttagtc caagtgcctg
     7501 atggtgtgga ctttggaaca aaagaggaac caaaaatcgc gacactctta tttgtagtgg
     7561 ctttaaaaaa agaacatcag ttagcggtgc tccaagattt agcctttttc tgttcagaca
     7621 tcgaccaagt aatggcgctc agtgatgcgg aaaccattga agaagtccaa atgatttttg
     7681 aacatggaca tatataacca atgttcacag taaaaaaagc tgccttgcat caagtaataa
     7741 cttcaaccaa gataaaaata agaggagcta tttttgttgg gaggttctta ttactgcgga
     7801 tgcaagcttt tgaaaactat ttattctaga aaaccgttta tttgaaatag gggacggtga
     7861 caaggttttt gtcaccgccc ctattatttt tgtgttttaa tagctctttt ttatatagat
     7921 agtgcccata cctatgaata ataaaacgat actccatata ccaagtgtca agataccatt
     7981 catgaaagta acctgttctg aagctagtgg cgagaaaata tctcctccta tgatcacatt
     8041 ttgaaaatca acataagaag ttggcaagta atgactgatt gattctatcc atccaatcga
     8101 agaaaacaag cgatactctg ctaagaaaag acaaagaagt gtacctaaaa gattgactag
     8161 agaatgttca aataaagcag atagaagaaa actgattgta cttaaaaaga gcacccacaa
     8221 caacaggaac agaaagctct ggaaaagata ctcatacatc ggcaggattc gtatctcctg
     8281 accaatgatc gttcctacag gataacggaa gtctcccaaa ccatttttga ttattactag
     8341 tatagagacg atcaaaaatg gcatcacgag acttagcata gctgcaccat aataaatggt
     8401 aaaacggatg ctatgtttct ttaccatact atccagtaat agattgacta gagagattac
     8461 ctgctttctt ttttcataag agatgatgga agaaagaaac aaggcggtta tacataaaat
     8521 caaaaaacta gaaatcattc ctgaaaaaat attttcgtag taatttgcta aagagagatg
     8581 cgctggcaag tcaaaaatag aatatctttg gatctgatgt tctttcatat aacggagcaa
     8641 ctcgacacgt ttttgttgtt caatgattgg aattccttgt ctttgaccag aaatcagtcg
     8701 atccagtata tctttttcat aatgataagt tgcttcgacc atttgctgga cattccctgt
     8761 gttttttgca tgtaagattg cttcgatcag tttgttgctt ttctctaaac tttccacaaa
     8821 ttctttctca ttctcatctt ctttcaacgt ttcaatcaaa cgttgcatct cttcatagtt
     8881 atgattcagt tcatcgaatt ctgtataagc aagtttatga tcaaaaaaaa gtgggaatgc
     8941 aaagagcacg accaacaata gaggaaataa aaagtttact ttgtttttta gtaagagatt
     9001 gcgttcaaat gtaagtaaag acatagttac acctcatata atttacgata aatagctaaa
     9061 atctcttcca tatttgagga ttctgtgacg atttctccat tttttagaaa acatgcttta
     9121 gaacaaatcg attggatatt cgcgatagcg tgggaagaaa gaagaatcgt cttcccctct
     9181 ttctgccatt gtctgatgag gctattcaag atatcaatac ttcctgggtc taatccgttc
     9241 aacggttcat cgaataacat gacagatgaa tcactgatca agtaagcagc aagcaagaca
     9301 tgttgtttca ttcctagaga catttttcca atcggcaaag taaggtactc agtcatcttc
     9361 aatcgttgga aaacagtttg gcattctact ttgctctgcc aatagtattt gatcaaagtc
     9421 aaataatcaa cagccgatag atagtcggat aactgattcg ttgattctag aaaaaagaaa
     9481 gaccggcgat aatctgtata agcagtagga gagatgttgt gaagggacaa ttgatcataa
     9541 gttgttggca gcagttgggc aatgccattc agcaaagttg ttttgccaaa tccgttcggg
     9601 gcaatcaaag cagctacttc tcctgattct actaaaagat tcaattgtcg aatcacacgt
     9661 tttttaccac gtttcatgtt catgtttttg atcagtaatg tcatagatag gcctccaata
     9721 taaaatttaa taacataata gaatggaaaa catctaaatt aaatgctaac aaaagttatt
     9781 gtttgcatat tataaaaaaa ttaaaataac agttttattt aaaattgaag ttttctgata
     9841 ccgaaatctt tttattttgc tgacatactc aaacctttgg cacaaagttt cgtgccaaag
     9901 tacgactatt tctcttttta gtaagcggat acaattagag tatcaaaagg agagagggag
     9961 agacaaaatg gaacggacga ttcccaaaaa caacatttcg ctaaaagcga gggtacaaaa
    10021 attaggcagt actttatcaa gcatggtcat gccaaatatt ggagcactga ttgcctgggg
    10081 tgtattaacg gctctattta tcccagatgg ttatttacca aatgaggctt tcgctaccat
    10141 ggtaagccca atgctaactt atctgattcc tttattgatc ggttatactg gcggaaaagt
    10201 aattgctggt gaccgcggat cagttgttgg ggcaattgca acgatgggtg tgattgtcgg
    10261 aacagatatt ccaatgatgc taggcgcgat gatcatggga cctcttggtg gatatgccat
    10321 caagaaattt gatcagctat tccaaaaacg gatcaaatcc ggttttgaaa tgctagtcaa
    10381 taatttttca gcaggtctta tcggttttgg attagcgtta ttaggttttt ctgcgattgg
    10441 tccagttgtc gatgcattga ctcaagcaat ggcaaaaggt gtagagatca ttttatctgc
    10501 ccatttgatt ccattgacaa gtatttttat tgaaccagca aaaatcttat ttttgaataa
    10561 tgcaatcaat catgggattt tgacaccatt gggaactgaa caagtagcag aggctggaaa
    10621 atctattcta ttcttgcttg aagcaaatcc tggtccagga cttggcgtat tacttgcttt
    10681 tactttgttt ggcaaaggag cagcaaaatc ttcagcacca ggagccatga tcattcactt
    10741 tttaggcggg atccatgaaa tctattttcc ttacgttatg atgaaaccgt tattattctt
    10801 atcagttata ggcggaggaa tgtcaggaag tttcattttc caattgatgg atgctggact
    10861 aagagcgcca gcttctccag ggtcgatcat tgcgattcta gcgatgacac cgttcaattc
    10921 ttaccttcct gttattttgg gcgtgattgt tgccgcagct gtttcgtttg gtatttctgc
    10981 agtaattttg aaagcggatg cgaaagatac aaatgaagac ttcgaaaaat ctgttcaaga
    11041 gacaaaggca gctaagcaag cttccaaagg tgcccaaggt attcctcaag gagctacatt
    11101 ctctggcgta caaaaaatca tttttgcttg tgatgcagga atgggatcaa gtgcgatggg
    11161 cgcttcgatc ttgagaaaaa aagtacagga agcagacttg cctcaaacgg tgaccaatca
    11221 agcaatcagc caactgacag atgactcgaa tacattgatc gttactcagg tcgaactaca
    11281 agaaagagca aaacaaaaag caccgagcgc gcgttttgtc tcagtagaaa actttttgaa
    11341 ttcacctcga tatgatgaaa tcattcaaga attaagcagc aagcagaaaa catcagtttc
    11401 tgaaattgag aatgagccag cagaagagtt tctttcagca aacatcaaac aaatcaaaga
    11461 gattctactt gtccacgatg atcgttccgg atcagcaaca atggggatga ccgtgctcaa
    11521 agatatatta gacaagaacc atttaactat cccgttaaga aaagtcaata tccaagattt
    11581 aaaagatgaa cctgattcac tgatcgtagc caaagaaagt ttagcggaaa aagtacagat
    11641 ggctgcacct caatccattc atttatcagt caacagcatg gtcaatccgc aaaaatacga
    11701 atcgattgca caatatttga aacagacagc ttaagggagg aaaacagcat gcaaagtttg
    11761 ccattcgaca tgatcgagct caatcgatct tttaaaacca aagaagaagc gatccgctat
    11821 tgcggtcaga tgcttgtaga agcagggtgc gttgatgagg aatatatcga tgccatggta
    11881 gatagagaca aaatgttatc tgtttatatg gggaatttta tcgcgattcc tcatggaaca
    11941 gatgaagcaa aaaaatatgt gaaaaaatcc ggcatctgtg tcgttcaagt accagatggt
    12001 gtagattttg gtaccgaaga agaagaaaag attgcgactg ttttgttcgg tattgcagga
    12061 gtcggagatg agcatttgca acttgtacag caaatcgcac tttattgcag tgatatggac
    12121 aatgttgtcc agctagcaga cgcgctcagc aaagaagaag taacggaaaa tctagcaatt
    12181 gcttaaggag agagaaaaat gagagcagta cattttggtg caggaaatat cggtcgagga
    12241 tttattggag aggttttggc agctaatgga tttgagatta ctttcgtaga tgtgaatcac
    12301 acgatcattg atgctttaaa tgaaagaaaa gaatacgaaa tcgaattagc agatgaatca
    12361 aaagaaaaaa tcactgtaaa aaatgtcaaa ggaatcaaca atcaaacaaa tccagaaaaa
    12421 gtaatccaag aaatcgctga agcagattta gttactaccg ccattggccc gaatatctta
    12481 ccttttattg ctgagttgat tgcaaaaggt atccaagaaa gagaaaagga aggaagcaca
    12541 acatctttag atatcattgc ctgtgaaaat atgattggcg gttcagcatt tctagaaaaa
    12601 gaagtgtata aatatcttcc ggaaacatca tttactgaca aatatatcgg ctttccaaat
    12661 gcagcagtcg atcgaatcgt cccattacaa caccatgaag atcctttatt cgtccaagtg
    12721 gaacctttca aagaatgggt cattgacgat agccaaagaa aaaataaaaa aatccaatta
    12781 aaaggggttt tatatgtaga tgatctagaa ccatatatcg aacgcaaact atttagtgtc
    12841 aatactggtc atgcgactgt cgcttataca ggtgccttgt taggttacca gaccattgat
    12901 gaagcaatgc aagatgcgtt agttgtggca caattaaaat cagttttgca ggaaacagga
    12961 agtttgctga ttgccaaatg ggggtttgat gcagagcagc atcatgcgta tattgaaaaa
    13021 atcattcatc gcttccaaaa caaaaatatc tctgatgcga tcacacgtgt cgctcggaca
    13081 ccattacgta agttaggtta tcaagaaaga tttacacgtc cagtgagaga actacaagaa
    13141 cataacttga cttgcccaca tttgacggca acaatgggga ttatttttaa ttactatgat
    13201 cctgaagatg aacaaagccg tcaattgcat gaaatgaaga tccatgaaaa cttggaacaa
    13261 ttgattcaag aagtcacagg aatcaatgat ccgaaaacaa tcgggaatat caagcaaaac
    13321 gtgaaccgtt atgccaagca agtcgcttaa aataggatac gaaaaagggg aatgtgacga
    13381 aatttttgtc acattcccct ttttcgaata actaggctgt ttgtccttca agatagggca
    13441 gatccaattc tttaccgtaa cgttgttcta aagctaggcg gatcaaacga gctgccaggt
    13501 tctcatttct tgcaaggata ggtccatgga aataagaacc gaagacattt cggtaaatga
    13561 caccttcaga ttggtcttca ccattatttc cttgaccttg taccactttc cccaaaggtc
    13621 gttcaccttc acctaagaaa gtccgaccat tgtggttttc aaatccataa taagtttcat
    13681 tgaattcttc gttatggata acgatatcac cgataaaccg gttattttcc tgacttaacg
    13741 tgtagtgatc cagtgcactg attccttgga tcttttctcc attagctccc atgtagtagt
    13801 gacctagcaa ttggtagcca ccacaaatgg ctaacatgac gccatcattt tcgatatagt
    13861 tgatcaaaga atctttcttt ttctggatgt cttttgaaat gattaattgc tcaaagtctt
    13921 gaccaccgcc aaagaaaacc aagtcatatt tatcagcatc aaaaggttca tgtatactaa
    13981 cgatctccgt atggcaagaa acccccattt tttctgctat atatttcaac atcaaaaggt
    14041 ttccgttatc accatatgtg ttcatcaaat ttccataaag gtgggcgata ttgagttcat
    14101 aattagccac ggttcattcc tcctttgata aatccttgag cagctagttc tttacgaagc
    14161 tgcaatacag cagtgtaagt agctaaaata tagacatgct cagttggcaa ttctttgatt
    14221 ttttcgatta cttctggtaa ttcttttgtt tctgtcaatt tattttctgg aatcccggca
    14281 acttttagac gtaaagtcat atctgtatga cggtctcctc cagaaataac agctgggata
    14341 tccatatcgg caaagttttc aaaattacca tcccaaatcc agctgacatc gattccgtct
    14401 gcgtaattgg catttaataa agccactaaa gaaaatggat aaggagctag accaatcata
    14461 tcgattactt gattgatacc tacaggattt ttgacaagta ctaatgtaca ttttttccca
    14521 ttgatattga tgacttcttg tcggccgaat actttctcgt catatcctaa accttgtttg
    14581 attttatcag gatcgacatt gaagtactct gccactgcag tagctgctaa agcattgtag
    14641 acattataca taccgccaac ttcgattccg tattcatgac catcgatcac gaaatctgct
    14701 gacacattgt ccatccgtac catatcagtt aatcgataat ccaattcagg acgtttgaag
    14761 tcacaatttg gacagtaata tttccctaag tttgcataag tgatcatttt ataatgcaag
    14821 atgtgatgac aatttggaca taagacaccg tctgtattgt aatgagccat ttgttcacga
    14881 tcttcttcat ggtcaaagcc ataatatttt ctaggattga ctgtttcgat agaattgaag
    14941 attggtgaat caccgttact gataatcgtt gcatttggtg actttgcggc accgtctaca
    15001 atcattttat aggtcgtata gatttctcca taccgatcca tttgatcacg gaaaatattt
    15061 gtaaataaga acagttctgg tttcatatat tctgtgactt tgctcaaact tgcttcatct
    15121 atttctagga cagcaaactt tttctgtcct ttttttggtt ttgcctgcaa gaaagtcgat
    15181 acaattccct gtaccatatt cgcaccagta gggttggtta gaacttcatc gaattgctgg
    15241 cgcaaaatat tgactgttaa agcggtagtc aatgttttac cgtttgttcc ggtgacaacg
    15301 acgacttggt agtcttttgc caaactatct agtatatgtg gatcgacttt cagcgctagt
    15361 ttacctggta aacttgatcc gcctttaaaa aaagttttta atgcccattg cgacgttttt
    15421 ccaactgcaa tcgcaaaatg actgcgtatt cccattatgt aacctccaaa aacgatttgc
    15481 tgacgaataa attcaactaa tcataccata tgttgaaaaa aaggttaaat tgcttttctt
    15541 attcttaaga aaaggttacg gctgaaagtg catgaaatcg gacaaaatcg catgatttaa
    15601 caaaaaaaca gcttgaaaca aaatgattgt ttcaagctgc tgtgatttta ttattccctc
    15661 ttacctatat tcccatttta accgataata attttctcgc ttggatattc atagcctaga
    15721 tctcgtgttt cttttggcac gaataacatc aatgtatata gcattccgat ccgcccaata
    15781 aacatcagtg tagcaatcgt gattttgccc acaacagaca agtctccggt aatccctaaa
    15841 gataaaccag ttgttccaaa cgcagaagtt acttcgatga tgatcgagat cagcgtttgt
    15901 tcttctgtag cagataaaaa aacgatacaa aagaaacaca taccaagaga aagcataaag
    15961 acaacgactg attttcgcac atcatcttga tcgattctcc gtccaaaaat attgatgtta
    16021 tcttcacttt tgaggaagga atatagatac aaaccgatga ttgctacagt agttgttcga
    16081 atcccgccgc ctacagaact aggactgcat ccgataaaca tcagtaaaga aaaaatgatc
    16141 agtgttgtga tttgaaaatc acccaaatcg tgaatctgca gaccagcatt acgagtcgta
    16201 atcgaataaa acatcgaatt gatccatttg acactcatat tggaatcttg gaataaatgg
    16261 tccttttcca atagataaat caagacagtt cccgaaacaa acaagataac aaaagctaac
    16321 acagctaatt tggtaaacaa ggaaaaacga aacggaagct tcgcattgga acgtttgtat
    16381 aatagccatt cccggcactc catcaataca ggaaaaccaa ttcctccgac aaaaatcaaa
    16441 aacatgatca ggatcaagaa aaaatagtca tgtgcaaagg gcttgatgga atccccagtg
    16501 acgtcaaacc cagagttcgt gacagccgat atcgcctgat aaaaaccgta aaaaacggca
    16561 tcacgccaac gatcaaaata gcctctgtaa taaaaataaa tagaaaagaa tgtcccaaaa
    16621 agtaattgaa accagattaa aatagcaaaa gtgatccgaa tcagtcggac gataccagac
    16681 aaacgcggtt gattcatatc cgtcatgatc agctgtcgct gtttcagtgt gatccgtcgt
    16741 ttagaaaaaa tgacaaaagc agtagaaatc atcatgatcc ccaaaccacc aacttgaaat
    16801 aatatttcca gcagtataat accgttatca ttgaacacag aattgatatc aaaagtcgat
    16861 agtccagtca cactcactgt actgattgcc atgaacagca tgtccacaaa agaaacatgg
    16921 ctatctggtt cgcgaaaaat cggcatataa aatagaacga gtgataagac cgtcatcaat
    16981 atataataaa aaacgatgat ttggatcgat gagaaatgat tggcagcaaa cttctgtcct
    17041 cgccgctgca gccttcgaaa gaataaatca acatgcacag tactatcctc ctgacaatag
    17101 tcgtttctac cagtatacaa ggggaattag gaatactcaa agaaattatc aaacagataa
    17161 caatacagct ttcgattaaa atagaaatgg cttataataa ggaaaatcct agaaaaaaga
    17221 aggaggagga ataacaaatt gattaatgct caacaaatcg tagaaaaaat gaaaaatcaa
    17281 aaaataaatt atgatacagt tctgaaaaaa atgatcatgc aatgggagaa agaagaagta
    17341 aagcctaaga tattaataca tacatgctgt gctccttgca gtacgcacac attggaattc
    17401 atgtctcaat atgcagagat cacgttattt ttttcaaatt cgaatattca tcctaaaagt
    17461 gagtatttgc gaagattaca tgaacaaaaa cgatttgtag accaatttaa tgagaaaact
    17521 gaccatcatg ttgcgctaat cgttgatgaa taccgtccaa atgaattcac caaaatggtt
    17581 ttaacaaacc atcttgaaaa cgaaaaagaa ggtggtgctc gctgcagtgc atgcttcaat
    17641 atgcgattag atcttgttgc gcaaaaagcg caagaactag gatacgatta ctttggaagt
    17701 gccctgacca tctcgccaaa gaaaaatgca gctttgatca atcagatcgg aatggatatc
    17761 caaaagattt acgggacaca atacttgcca agtgatttca agaaaaacaa aggctatgaa
    17821 cgctctttgc aaatgtgcaa agagtatgat atttatcgcc aatgttattg tggttgcgtg
    17881 ttcgctgcca agcagcaagg atgcgatctg aaagaaatca atcgggaagc aaaagcttac
    17941 ttaaaaacat caaccgtagt ttttgaggaa aattaaagaa atctttcgga aaaacgtaag
    18001 aaaaaaataa agaatttatg gtagaaataa ggtagactgt ataatttgtc cgtagtaaag
    18061 taaggaaaca agaataaatt tcaatgaagg aagagataag atgcgaaaag tagcacctat
    18121 tttgaagcca atcgctgtat taacaatctc gacgattgtc gcgactacta caggtattgt
    18181 gaatagttcc agctaccgtg caccaagttc aagttctagt actgtagaag aaacaacacc
    18241 aactacttca gtctcgacat ctgaaccaac aacaacggaa agtttgaatg aaaccactac
    18301 gacaagtaca tgggacgata caacaactag ttcgtcgtat gatgagacat atacaactga
    18361 cagctcaagc gaaacaagta atacggtacc agatggcact ccatcggatt caaccaatcc
    18421 aagtacaagt ccggatacaa gtgctagctc cgaaacgata ccaagcagta cgactgtaga
    18481 tgataacacg caaaatgatg atgcagcacg tacagcacag caaaaccaag attcaggaaa
    18541 tacccaaacg tataaccagc aagcaggtga ttctcaatga catttttact agaccttatc
    18601 aacggggtgc ataaattcct tggctattta gacatcagtc ctaaatatct taaccgtgga
    18661 tatacgattt taagtgtgat tcccacgctt tatttattga gaattgttta tggactttgg
    18721 caaaaccaaa actatcttca atttttctta tatggacttg catttctagt gcttgtttat
    18781 tttactgttt taaatgtatt ttattacttt ttagataaaa acacgaaagc cgatgtcact
    18841 cagctttttg tgaagtattt acctgatgaa gcgttcaaca tccagacaga agaatcgata
    18901 gataatggaa attcgatcga taaagtgaat acacaagagg tcatggtttc ttatgacgaa
    18961 gattatcaat tgaaattagc cgagaatatg cggtatttga ttggaaatgg tgagatcaaa
    19021 acaaatgaac tcggtcgcat ggatggattt ctggtcgata gaaatacatt gtatccttat
    19081 tactatgtca agaaaacagg agagaaagag tatgttctaa atattggacg aagctactcg
    19141 gacatggaaa aagtagggac cattcgactt gactcaacag aagacacatt ggaacctgtc
    19201 ggattgttca tcgtcggcgg tgattttgtc aaagacgggt tacgctatca tgagccttat
    19261 cgtctgaaat tgattgcaaa aaaggcacag tcgcaggaag aaccagtggt ttatagtcgt
    19321 agccaaagaa gaagacattc ataatgtgat gaaacgccgt gtatcagtgg ttgcgataaa
    19381 aacgtttatt cggaataagg gggatgtgac acgtcttttg tcacgttcct tttttatata
    19441 acgagaaaga taagacgaac acatcactta ttctttcctt tcatttataa acattgtaga
    19501 ataaagaaag tacaacgaag tattgtgaaa aaacgtaata aataacgagg aaaatacaag
    19561 taggaggtaa gctgtgaaag aatttttgaa aaattggggg attttgatcc ttgtattagc
    19621 ggctatttta ttagctagag tgtacgtgtt tacaccagtt actgtaaacg ggcattcgat
    19681 ggaccctaca ttaagtgatg gacaacgatt gatttcatct aagatctcaa actatgaacg
    19741 aatggatatt attactacaa aggaaccggg ggatgaagaa cggatgattg ttaaacggat
    19801 catcggtatg cctggagata cagtcaagat ggaaaatgac cagttgacca ttaatggcaa
    19861 aaagtatgat gaaccttatc tggatgagtt caaaaaagaa ttttcagaag ataagttaca
    19921 aggagaatat gcttatagct caggattcca agcacaagca gaaagttcat ccacctttac
    19981 gagtgacttt gaatatactg tgccaaaagg aaagtatctt gttctaggcg ataaccgctt
    20041 gatttcaaaa gacagccgaa tgtttgggtt agtcgacaaa gatatgatcc aaggaaaagt
    20101 tgttttccgt tattggcctc tttcagaaat taaaatcatg tgatgaaaaa ataaaaagaa
    20161 gctgtgacat gttttttgtc acagcttctt tttccgaaaa ttccttctta tttcttggag
    20221 ttgctcactt tttttgcaat ctcattttaa gctttttggc tgatggataa gaaaagcgaa
    20281 gcgtttttgt tcataaatag cttttcccca cgatggaagg tatgactagt agcagagaca
    20341 aagcccgttt tttccaatcg attattcaat tcttcttggc taaagccatt atggactttc
    20401 ggatgactaa tttgttcatt cttgtcaaag tctacgatga tcaattgacc gccaggagct
    20461 aaaatttcat aaagttttgt aagaatattc tccgtatcag gaatgtgtaa aagtacaagt
    20521 gatagaagga tgagattagc ttggacagca ggaaattcga cagaagcatc agcgtggatc
    20581 gttcggacat ttttcagatc tgctgcttgg atcttttctt ctgccatttt cagcatagtt
    20641 tctgaagcat cggcaatgat cagttctttg aatctttccg caagcggtaa actaacaagc
    20701 ccagttccgc ctccgtaatc cagcaggact ttttggtggc tgtcgcgcgg tagataagta
    20761 gttagttctt cgcgaataat cttggctaat gcttgacggt caggggaatc ataatggtta
    20821 gcgatggaat caaaaatatt ttttgtcatc aaatagctcc ttacgtaaaa ctttgaaatt
    20881 ttaacttatt atagcacgtg aaaagaaaga aagcatgcta tactcaattc aaaaagggag
    20941 aatctagaaa gaatatgccg atatcgtttg taaaagatag agaggaaaaa ggaaagtgtg
    21001 tccgagaaat attactagac ttgcctgagt ggtttgggct tcctgaatca acggaaaaat
    21061 atatcgagga atcaagtaaa ctacctttat ggtgtgaaaa aagaaaagaa gaatatttag
    21121 gctttatcac tctttcacag acaagtgaag atactgccga aatctattct attgtatggg
    21181 aataaaaaaa gactatcatc accaaggatt aggaacaaaa ctttttaaag aagcagaagg
    21241 ttacgcagca aaacattaca aatatttgca agtgaagact gtagacgagg ggcactactc
    21301 tatatatgat caaactattt gtttctacga atcattagga ttttcaaggt tggaagtttt
    21361 tccaaattta tgggatgaat ggaacccatg tttagttctt gtcaaaaaat tggaacaaaa
    21421 gtgagcaata gatttaatac taatctgtgc ttgatgaaaa ttctcactgt aaaaaatgct
    21481 gaaaatcaag tataatacca taggaacaaa ctggaaggtg aaaaagagca tggcacaact
    21541 attttttaag tatggcgcaa tgaatagcgg caagacgatc gagatcctaa aagtcgcaca
    21601 taattatgaa gaacaaaata agccagttgt cttaatgaca agcggtattg atacaagaga
    21661 tggtttaggc gttgtttcaa gccgaatcgg actgaaacgt aatgcgatgc cgatatttga
    21721 agaaacagac gtatttgacg taattcagaa aatggaaagc aaaccctatt gtgtgctgat
    21781 cgatgaagcg caattcttaa aaaagaaaca tgtcattgct tttacgagaa ttgtggacga
    21841 attggatatt ccggttatgg catttggttt gaaaaatgat tttcgaaacg agttatttga
    21901 aggatcaaaa tatttattgc tttatgcaga caaaatcgaa gaaatgaaaa caatctgttg
    21961 gttctgccac aaaaaagcaa tcatgaattt acattatatt gatggaaacc ctgtttatga
    22021 aggcgatcaa gtgcaaattg gcggaaatga agcttattac cccgtttgtc gaaaacatta
    22081 ctttcaccca tcaatgatta cagaaggaga ataagcatgt acgatcaatt acaagcaatt
    22141 gaagaccgtt atgaagagct tggagaactt ttaagtgacc cagaagtgat ttctgataca
    22201 aagcgtttta tgcagctttc aaaagaagaa gcaaacacgc gcgaaacagt cgaagtttat
    22261 cgtcgttata aagaagtagt acaaggaatc accgatacag aagaactgct tggtgaaaaa
    22321 ctggatgatg aaatggctga actagcaaaa gaagaattat ctgaattaaa aaaagaaaaa
    22381 gaagtcttag aagaaaaaat caagatcttg cttttaccaa aagatccaaa tgacgataaa
    22441 aatatcatca tggaaatccg tggagcagca ggcggagacg aagcagcatt attcgctggc
    22501 gatcttttca atatgtacca aaagtatgct gaagcacaag gctggaaaac agaagtgatg
    22561 gaagctaacg ttaccggaat cggtggatat aaagaagtga tcatgatgat caccggagac
    22621 aacgtatatt cgaaattaaa atatgaaagt ggtgcgcacc gcgtccagcg tgttccttca
    22681 actgaatcgc aagggcgtat ccatacttcc accgcaacag ttgtcgtgat gccagaagct
    22741 gaagaagtag agatcgatat tgaagacaaa gatatccgta cagatatcta tcatgcttca
    22801 ggtgctggcg gacagcacgt caataaaaca gcatctgctg tacgtttgac tcacttacca
    22861 acagggatcg ttgttgctat gcaagatgaa cgttctcaaa tcaagaaccg tgaaaaagca
    22921 atgaaaatct tgcgtgctcg tgtgtacgat aagatccagc aagaagcaca aagcgagtat
    22981 gatgccaatc gaaaatcagc agtcggaact ggggatcgtt cagaacggat ccggacgtat
    23041 aatttcccgc aaaatcgtgt gactgatcat cgtatcggat taactatcca aaaattagat
    23101 cagattttag cagggaaatt agatgagatc gttgatgcat tgatcatgta tgatcaaaca
    23161 tcaaaactgg aagctatgca aaatgggtaa aatgacctat cgagaagtcc tgtcacgggc
    23221 ttcttctttt ttagaggatc atgggaaaga agcatatagt atccaatttt tatttttgga
    23281 acgaaaacaa tggaaaaaac ttgattggct ccttcatatg aacgaagaga tttcagaaga
    23341 agaacagcgg ttgatcgaaa ccgatctgcg acttctgctt gcagatcatc cacctcagta
    23401 tttgctagga tatgcagatt tttatgatca tcggttaaag gtaactgaag caacactgat
    23461 ccctcgacca gaaacagagg agttagtcga atggtgttta gacgagacgc ctggtgtacc
    23521 gttagaagtg atagatattg ggacagggac tggagcaatt gctattagtt tgaaagcagc
    23581 aagaaaaaat tggcatatat ctgctgtgga tctttcagaa gaagcattag aagtagcgaa
    23641 agaaaatgct cagaaagaag gaacgaaaat cagtttttat catggagata cattaggacc
    23701 agtaatggat cagcaatttg atgtgattat ttctaatccg ccgtacatca gtcggaatga
    23761 atgggaactg atggatgaaa gtgtccggtc attcgaacct aaaatggccc tttttgctga
    23821 gaacgatgga ttagctattt atgaaaaaat agcagttgaa gcaccaagcg tactaaaatc
    23881 aaatggaaag atttttttag aaatcggatt tcgccaaggt gaagcagtaa aaaaaatatt
    23941 tcagcaagca tttccagata aaaaagtggc gataaaaaag gatctttttg gcaatgaacg
    24001 aatgatccaa gtttatggtt gaagttgtgg atgaaaaatt ttttatttgt ttttttatta
    24061 taaaaaaaca cttatttgac aaggatgtaa acgacttttt ggtttatcaa caagtttatc
    24121 cactattgac aaatagatta tccacaaaca gtggaaaact tgaggataaa ctcagacaaa
    24181 ataagaatgt atgaaaaagg ggttgtggat aaactgtgga aacgaaacga tatgatgaaa
    24241 cagaattgca agaggcagcc gaagcactga aagaaggaga acttgttgct tttcctaccg
    24301 aaacagtata cggattgggc gccaacgctc ttttaccaaa cgctgtcaag aaagtgtttt
    24361 ctgtaaaagg gagaccgcaa gataatccat taatcgtcca tgtcgcctct tttgaacaag
    24421 taaaagagta tgtggacaac tttcatccgg cagcagagaa gattgtgaag aacttctggc
    24481 ctggaccatt aactttgata tttaagatca aaaaagacac tttgccctca gttgtgacgg
    24541 gaggattatc cacagctgca tttcgtatac cggataacaa aaaaacacta gaagtaatcg
    24601 aactttccgg tgttccgctt gtcggtccaa gtgcaaatac gtcgggaaaa ccaagtccaa
    24661 cgactgcaga tcatgtatat catgatctac aaggaaaaat taccgggatt attgatgatg
    24721 gagctacgcg aattggtgta gaatccactg ttcttgattt aagtgatcca acagccatgc
    24781 ctatgatttt acgaccaggt gcagtaacga aagaacaaat cgaagcagtc atcgaatctc
    24841 ctgttgctat tgatcagcat cttgtaaaag aaaatgaaac accaaaagcc cctgggatga
    24901 aatacaaaca ctactcaccc gatacacgtg ttctgatggt cagagatggc gattggtcaa
    24961 ctgcagttca atgggcaaaa aataagaaga tccgtgcagg tgtcatagca agccccgaaa
    25021 ttgcggatca agtgcggaca gatactgcag ctgtttatat gtataacgac aactcagtag
    25081 aagcggcggc taaaggattg tttgcaggtc taagaggatt agatgaacca acacttggat
    25141 tagatttgat ttttgtacaa gtgtatccag aaactggatt ggggaatgct tacatgaatc
    25201 gcttgaaaaa agcagcagga caaaattatt ttgaaaaatg atcaattggt tattgtcgca
    25261 ttcttttagt atgatacaat gctatcaagt aaatcttcta tcagtgaacg aaaaactaag
    25321 cgtaactaat cgtaatagaa gagatacgaa tatttggcaa tttgtttttg atgggaaaaa
    25381 taaaattgta ggaaaataaa attgtaggaa aataaaaagg agctgttgtt tgtggtagat
    25441 tacaaaacgt ttgaccctga tctttgggct gcgatcgcca aagaagaaga aagacaagaa
    25501 cataatttgg agctgattgc ctctgaaaac tttgtctccg aagcagtgat ggctgcacaa
    25561 ggaagtatct tgacaaataa atacgcagaa ggttatccag ggcatcgcta ttatggtggg
    25621 tgtgaatttg tcgatatcgt tgaaaattta gcgattgacc gtgcaaaaga attattcgga
    25681 gcgaaatttg cgaacgtcca gcctcactcc ggctctcaag ccaacacggc tgcttatctc
    25741 gctttggtag aaccagggga cacgatctta ggaatggatc tttccgcagg cggacatcta
    25801 acacatggat caccagtcaa cttcagtggc aaaacctatc actttgttgc ttacggtgtt
    25861 gatccgacaa cagaagttat tgattataat gtggtacgta ttttagctag aaaacatcaa
    25921 ccaaaattga tcgtagcagg tgccagtgct tacggacgaa cgatcgactt tgcgaaattc
    25981 agagaaatcg cagatgaagt aggcgcaaaa ctgatggtag atatggcaca tatcgcagga
    26041 ttagtagcag caggacttca tcctaatcca gttccttatg cagatatcac aacgactacc
    26101 actcataaaa cattgcgtgg ccctcgaggc ggcatgattt tgacaaacga tgaagcatta
    26161 gcaaaaaaaa taaatagtgc ggtatttcct ggtattcaag gcggccctct agagcatgtg
    26221 attgcgggta aagcagtagc attcaaagaa gcattagatc ctgcatttaa agaatatagt
    26281 gaacaaatca tcgccaatgc aaaagcaatg gtcaaagttt tcaatcaagc aattggaacc
    26341 agagtcattt caggggcgac agataatcat ctgatgttga tcgatgttcg cgagttaggt
    26401 ataaatggaa aagaagcaga gagcattttg gacagtgtga atatcactgt aaataaaaac
    26461 tcgattcctt ttgaaacact aagtccattc aaaacaagcg gtattcgaat cggcacgcca
    26521 gcaatcacta ctcgcgggtt caaagaagaa gatgctgtaa aagtggctga actagttgtc
    26581 aaagcattac aagcaaaaga tgataacgct caactagacg aagtcaaaac aggtgtacgc
    26641 gaattaactg aaaaatttcc gttgcataaa aaataaaaat ttaaattcca ttagtaaaca
    26701 gaaaagttca atgttgggct tttctgttta ttttttggga aaacggattc tttgacaata
    26761 tcggtgatgc tctctagtat atgaggtgta attttagtct tcacactaaa tctcagggag
    26821 gaaaagtcat gactgatcgt atctcgttag aaaaggaagc agtagcattc agtgatgcaa
    26881 atgcgcctca tccgcgtatc tatgaactag caccggaaga aggaagagtt ttactagaag
    26941 aagtacaaga atcacctgtg aacaaatatt ccgtcgatat tgaagacttg atggtggata
    27001 ctggcgaatg gggaaaactc aatattcgtc tcgtacgacc agaagggaat atggataaat
    27061 taccagttat tttttatatt catggagcag gctgggtttt tggcagtgct caaacccatg
    27121 ataaattgat cagagaactt gcggttcgta cgaattccgt cgttgtcttt ccagaatata
    27181 gtcgatcacc agaagcaaaa tatccaacag caattgaaca aaattatgct gtgttgcaac
    27241 agctgaataa attagccaag tcaaaaaatc tggatctcga gaatctaatc gttgcaggag
    27301 attcagtagg tggtaacatg gctacagtca tgacgatctt aacaaaagaa cgaaagggcc
    27361 tcccaatatc caagcaattg ctgtattatc cagtcacaaa cgctgatttt gatacagatt
    27421 cctatcatga attcggagaa aactattttt tgacaagaga aggaatgatg tggttttggg
    27481 accaatatac gacgaatgaa gaagagcgtg ctgaaatcac agcttcgcct ttgagagcaa
    27541 atataaatga actaaatgat cttccttcag caatgatttt aacgggagaa gcggatgtat
    27601 taagagatga aggtgaggct tatgcgcgca aacttcgtga tgcaggggtt cctgttacac
    27661 aagtacgctt ccaaggaatc atccatgatt ttgtcatggt aaatgctatg gatcagacaa
    27721 aggcaacgcg tgcagcaatg gcattatcta cttcttggat caagaaaaaa gaataagctt
    27781 tgcttgtccg caggaaaact tcttttcaaa aacggatttt cttaggaaaa atggcgagtt
    27841 tgactagtca atcacttgat tttgttttac aattaaaaag aaacgacaga acaaaggaga
    27901 gcttaaaaaa tgggcaaatt tcaagtgatc gatcatccat tgattcaaca caaactaact
    27961 attattcggg acaaaaactg cggaacaaag gtttttcgtg aagtagtcga tgaaatcgct
    28021 atgttgatgg catatgaagt atcacgggat atgccattgg aagacatcgt gatcgaaaca
    28081 ccgatcactg aaacaacaca aaaaacgttg tctggtaaaa aagtagcgat tattccaatc
    28141 ttgcgcgcag gtattggaat ggttgacggt atcttggaat tgattccagc tgctaaagtg
    28201 ggacatatcg gtctttatcg agatgaagaa acattggaac cacatgaata tttcgtcaaa
    28261 cttccagaag acattgatgc acgtcagttg tttgtagtag atccaatgtt ggcaacaggc
    28321 ggatcagcaa tcatggcaat cgatgcattg aaagaacgtg gcgcgtcgaa cattaaattt
    28381 gtttgtttgg tagcagcacc tgagggagta aaagctttgc aagaagcgca tcctgatatt
    28441 gacatctata cagcttctct agatgaaaaa ttgaatgaac atggttatat cgttcctgga
    28501 ctaggggatg cgggtgaccg tttgtttggt acaaaataag taaatacgaa aaagggtgtg
    28561 acacaacttt tgtcacatcc ttttttggtc atttttaacg tttgatgcag aacagctttt
    28621 tcacagcttt cgtttgcata taaaaaaacc atcccaaaaa tgcagagatg gtcaaattca
    28681 aatctttttt agttctttgt agttaacgat tactacaccc ttactttgcg tcatcaagtt
    28741 cgcattttct gcagtttcat caatctcaac aacagcggaa tttttcaatt gctttgaaat
    28801 cgttccagtt tgcgacttgc cgtgaattgt gaacattacg tgagtattga tcttgaattt
    28861 ttcaccaatt tccgatggta cgatagttgt atcaaatttt ccaaaagttg ccattttcat
    28921 aaaacctgcc tttcacatca attataccac gttttatgaa aaatatcatg aaattaaact
    28981 aattttccat cggactcttt acaatcagcc aaatagagta tataatttct tttggataag
    29041 gccagcttag ctcagttggt agagcaacgc actcgtaacg cgtaggtcgt aggttcgatc
    29101 cctatagctg gcattaaaag agaagacaga tatatcaagg atttttaatc cattgataca
    29161 tctgtctttt tgtttaaagg aaataaagta tgctttctta gcaatagagc atgtattatt
    29221 tctataaaaa tttaggagaa taaaacgact agcaatatag ctgtgaaatc aaatatcaca
    29281 tgaactgccc aacttgtaat gatcgagttg cttttaatgg cagcttggtt gaataacaat
    29341 cttgccaccc cttgtatcaa aaggatgtgt gctacagtgt gtaaaatatt tccattatca
    29401 taagtactgt aatggataaa tccaaagatg attgctgaca agaaactagc gacaggaatg
    29461 ctgaacttac tagaaaaaat agcgagaaaa tacactgaga acaattcttc tccaagtatc
    29521 atgataggca aaataataaa taataacggg ctgaaagcct catttattgg attgcctgtt
    29581 aaaccccatt tcaaaatttg ttgcaaaaat accgagactg cggcactgat tactacattg
    29641 ataaaaaaat atttggctat atttttgaca ggagcgacag gtttcgagaa catttttttc
    29701 gtatcttttt taccaaaaac aagtgtaaat gctataaatc cagtgatagt taaagaaaaa
    29761 atgctaataa tggatggcgc aaatagcaac cctaacaaac cgagtacaac gacaatagtg
    29821 cccaatatcc cttttttaag ttctattttt tttcctaaaa tgttattcat gataataact
    29881 cctactattc agtttttgaa gatagagtca gtatacatga agagttaaaa taggcaatgt
    29941 ttttttatgg atatttgtat tgctaaaaat ttatcttata tattcatttt gattatacta
    30001 cttttatttg taaaaatttt ctagcaaaac caagtgcttg caactgatta agcgtacaat
    30061 tttttagatg ttccgagcgt acttcaatca tttcaaagga gttgctactt aaatcgatat
    30121 tttttaaatc agtatcaaaa aagctagcat tttctaaatc attagtagaa aacattattt
    30181 tagtgaggga acagtctaca aaatctgcgc ttgataagac agagtgctca aaggtacttt
    30241 cttttatgtt tgaaccagat aaatttacat agtccatttt acaattctcg aataacgtgt
    30301 tcccaatata actttccatc aatttagtac ctgttaattt acaattgaca aatttcacgc
    30361 gatgcaacat gctttttgtc aatatacagc ctgaaaaatc acagttttcg aatatacagt
    30421 cggtaatctc cattctttga aaatcattgg aagcaaaaaa tgcatacttg aaaatagatt
    30481 tgtaaataat tggatggcag attatttggt tttcgatgac ctctttttgt gaaaggatat
    30541 tatacagttc aaaatcttcg ttttcataga tatgaaaaaa ggatccttta ttcaagcttg
    30601 cttcattaac tttaggaaaa atcatattta attacctcca ttttcataaa gtcatattaa
    30661 caaaagctaa accaacttac attagcagaa aatgagatag gttttcgcct ttttcgataa
    30721 cgatagtgtc gctatctctt gaaacgttct tagaattgcc ctgagagaca caaattaggc
    30781 gtaattctaa taaaaatctt agaataaaaa tttttactga tttaatttag aatgttttta
    30841 a
//
LOCUS       DACGEU010000026        29779 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.026, whole genome shotgun sequence.
ACCESSION   DACGEU010000026 DACGEU010000000
VERSION     DACGEU010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29779)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29779)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29779
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.026"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            <1..191
                     /locus_tag="IXR40_001117"
     CDS             <1..191
                     /locus_tag="IXR40_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4360979.1"
                     /translation="NFSKYLKKVRISKAKLFLTETRLTLTEICEKVGYTELGYFSRVF
                     KEETGMTPSQYRKGTFVK"
     gene            188..1924
                     /locus_tag="IXR40_001118"
     CDS             188..1924
                     /locus_tag="IXR40_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAQ4360980.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(1987..2823)
                     /gene="pheA"
                     /locus_tag="IXR40_001119"
     CDS             complement(1987..2823)
                     /gene="pheA"
                     /locus_tag="IXR40_001119"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HAQ4360981.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(2820..3329)
                     /locus_tag="IXR40_001120"
     CDS             complement(2820..3329)
                     /locus_tag="IXR40_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HAQ4360982.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(3322..4617)
                     /gene="aroA"
                     /locus_tag="IXR40_001121"
     CDS             complement(3322..4617)
                     /gene="aroA"
                     /locus_tag="IXR40_001121"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HAQ4360983.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(4630..5721)
                     /locus_tag="IXR40_001122"
     CDS             complement(4630..5721)
                     /locus_tag="IXR40_001122"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HAQ4360984.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(5738..6904)
                     /gene="aroC"
                     /locus_tag="IXR40_001123"
     CDS             complement(5738..6904)
                     /gene="aroC"
                     /locus_tag="IXR40_001123"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HAQ4360985.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(6906..7970)
                     /gene="aroB"
                     /locus_tag="IXR40_001124"
     CDS             complement(6906..7970)
                     /gene="aroB"
                     /locus_tag="IXR40_001124"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HAQ4360986.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(8003..9025)
                     /gene="aroF"
                     /locus_tag="IXR40_001125"
     CDS             complement(8003..9025)
                     /gene="aroF"
                     /locus_tag="IXR40_001125"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HAQ4360987.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            complement(9684..10658)
                     /locus_tag="IXR40_001126"
     CDS             complement(9684..10658)
                     /locus_tag="IXR40_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HAQ4360988.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(10639..12522)
                     /locus_tag="IXR40_001127"
     CDS             complement(10639..12522)
                     /locus_tag="IXR40_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HAQ4360989.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(12540..14765)
                     /locus_tag="IXR40_001128"
     CDS             complement(12540..14765)
                     /locus_tag="IXR40_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HAQ4360990.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEKKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            14880..15914
                     /locus_tag="IXR40_001129"
     CDS             14880..15914
                     /locus_tag="IXR40_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAQ4360991.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(15981..16994)
                     /locus_tag="IXR40_001130"
     CDS             complement(15981..16994)
                     /locus_tag="IXR40_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAQ4360992.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKQLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(17072..17260)
                     /locus_tag="IXR40_001131"
     CDS             complement(17072..17260)
                     /locus_tag="IXR40_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HAQ4360993.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
     gene            complement(17700..17828)
                     /locus_tag="IXR40_001132"
     CDS             complement(17700..17828)
                     /locus_tag="IXR40_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HAQ4360994.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(17831..19204)
                     /gene="rlmD"
                     /locus_tag="IXR40_001133"
     CDS             complement(17831..19204)
                     /gene="rlmD"
                     /locus_tag="IXR40_001133"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HAQ4360995.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(19315..20370)
                     /locus_tag="IXR40_001134"
     CDS             complement(19315..20370)
                     /locus_tag="IXR40_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HAQ4360996.1"
                     /translation="MKKARVIYNPTSGKELLKKNLEDILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(20380..21810)
                     /gene="gatB"
                     /locus_tag="IXR40_001135"
     CDS             complement(20380..21810)
                     /gene="gatB"
                     /locus_tag="IXR40_001135"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HAQ4360997.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(21807..23279)
                     /gene="gatA"
                     /locus_tag="IXR40_001136"
     CDS             complement(21807..23279)
                     /gene="gatA"
                     /locus_tag="IXR40_001136"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HAQ4360998.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKTTFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(23279..23584)
                     /gene="gatC"
                     /locus_tag="IXR40_001137"
     CDS             complement(23279..23584)
                     /gene="gatC"
                     /locus_tag="IXR40_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HAQ4360999.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(23690..25726)
                     /gene="ligA"
                     /locus_tag="IXR40_001138"
     CDS             complement(23690..25726)
                     /gene="ligA"
                     /locus_tag="IXR40_001138"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HAQ4361000.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTIKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(25743..27977)
                     /gene="pcrA"
                     /locus_tag="IXR40_001139"
     CDS             complement(25743..27977)
                     /gene="pcrA"
                     /locus_tag="IXR40_001139"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HAQ4361001.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLVNPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            28132..29691
                     /locus_tag="IXR40_001140"
     CDS             28132..29691
                     /locus_tag="IXR40_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HAQ4361002.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVEGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQNVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
BASE COUNT         7966 a         6471 c         5490 g         9852 t
ORIGIN      
        1 tcaacttttc aaaatatcta aaaaaagtcc gtatcagtaa agccaagctc tttttgacgg
       61 aaacacggct tactttgacg gaaatctgtg agaaagtcgg ctataccgaa ctgggttatt
      121 tctccagagt ttttaaagaa gagacaggaa tgacaccttc tcaataccgt aaaggaactt
      181 ttgtaaaatg agaaaaaaaa tcaaagagca tgaactcttt gccaaacttc tgttcatttt
      241 gttcatcggt ctttttctgc aagccatcgt catttctttg tttatttatc atcgatcaag
      301 ggatgcctat atccagctgt tcaatcaatc gaatgatgtg gtactaaaaa agattcaatc
      361 tgaatttgaa agtttgaatg atacaatcga gaatacatta gccgcttttg attctaatcc
      421 agctgtcaaa agctattttt ccaatgatcc agcccaacat atggaacagc ttcagcaact
      481 aagaacaatc caaaaaatga atgactctct ttcaaaaatc catccaatga tcgattacga
      541 tgtattgatc tttggagaaa atggaagaac ttttgtcgga aacgacatgc tcactgccgt
      601 atctgccgat tctttttttc aatctgcgat tgctcagaga gtgaatgaac gtgctgctga
      661 tacacaaatg ctttttgcac accacggatt gactcttcgc gataagaaag cacccagcgt
      721 cttctttgtc aaaaaactga aaaatacatt gaatcacgtt tacggatatg ctgttttatc
      781 gatctcatcc aagcaactag cgaatctttt tcaatctgta gtaaatcctg agatatcgaa
      841 gatctccttc atgaacgaag aacagacgat catcgcatca aatgaagaaa atacaattgg
      901 gagccgatca atgattttca aaaaactaac agtaggtgaa acaacgattt caaatggaca
      961 gcagttgacc cgtcttcctc tgtaccgcca ggattgtaca ttactcagtc aagtcgatct
     1021 tcattcttta tctaaccaaa tgggcgtgat ttttccgatt attttgtata atatcgtgac
     1081 acttgctttt gctggctcat tggtatttat gtatttggat cgacacacaa aatcgatcta
     1141 ccgcttgatt gattcgctaa aacggctaga ggaagatggc ttaaaagcta ctgttcctgt
     1201 acaaggaagc catgaagtcc aattgctagg gaatacgatc aatcaattgc taagtaatgc
     1261 tcagcatcat tatgaacaga cgatccaaga cgaaaagaag aaacgttcgc ttgaaatcca
     1321 aactatgcaa gcacagatac agccccattt tatttataat acgctgacta gcttgaaatt
     1381 tttgatttgg cagaaaaaaa cagatgaagc agttcaagga atcgacagtt tcattacttt
     1441 actaagaagt acgattggga aaaaagaaga agtgattcca gtcaaggaag aaatcaaaag
     1501 cgtacaaagt tacatcgatc ttttgagtat gcgatatggc gaaagaatct cggctaaaat
     1561 aatgattcct gatgaactgc agtcattatc tatgccgaat atgatccttc aaccaattat
     1621 cgaaaacgcc tatcttcatg cttttcacaa taaaacgcaa ggattcatca cggtgtacgg
     1681 caaaacaaaa aatcagcttc ttttattcga agtgattgat aacggcgatg gcttcgatac
     1741 tgaaaatacc aaacaaaaaa atgatcattt ttcaggaatc ggcatcagcc atgtagatga
     1801 gcggatacgc ctaatgtatg gcgatgcata tggcttaacg atccaatcag tgattgggac
     1861 aggaacgact gtaacgattt gtctaccgct tcttcctaaa aatcaatcag aatatcaaaa
     1921 ataaagaata gccaagcgct gattttttta ttttaagtta aataaatcaa tcagtattct
     1981 tgactttcat ctacgcgtct cttctactgt cagcactgga taacagccca atatttgact
     2041 ttctcctccg agcatcttga tttcttggag cgcattctct actaatgtca ttggacggtc
     2101 caacaacaaa tcgatcacga aaaaatattc tcccaagcta gttttcaatg gtcgggattc
     2161 aatcttactt aagttgattt cccgccagcc aaaagctgcc agcattttat gaagcatccc
     2221 tggccgatta gcaggtagtg tcaagatgac actcattttt actggagctg actgctggct
     2281 ggtcatcttt cggtcaccga cgatccaaaa acgtgtctgg ttcaactcat tatcttggat
     2341 attctcagct aagatctcca atccaacatg ctgtgctgtt tctaatgaag caatcgctgc
     2401 tgcgtcttct ttcggatgtt ctgctacata cattgctgca gcagttgttg attctgttgc
     2461 tactaaagga acattaggat aatgcgtttc taaaaactgt tgtgattgtg ctagtgcttg
     2521 tggatgtgaa aggatttttg taatctttgt tgctggattg cctaaaagct gctgcttgat
     2581 aggaagaacg atttcacttt taacttcgac ttctggatgt ttggaaagaa gatcgattgt
     2641 gtgatgaaca gctccttcca atgaattctc tacaggaacg acagccagat cgacttgttt
     2701 gcgaaacaaa gcgcgcaaac aaacagggat ggaagcatac gcagtcaatt gttctgtagg
     2761 aaatagctga caagccgcct gataagtgaa tgaactttct ggccctagat agctgacgtt
     2821 catatgcttt tgatcctttc tataatggta tcgatgatct tttctggtgt ttgattggtc
     2881 gtgttgattc gatgtgtcgc actttcttca taccaagaaa gtcgttgtgc caataatgct
     2941 tttatttctt ctcttgtttt tccaagagct aaaggtcgaa tagacgtttc atcttgttgg
     3001 atacgatcaa ctagacagtc cgcttctgcc tctaagtaaa gaacaatcgg ctgtgttttt
     3061 aaaaaacgcc gattttctgc actttggaca atccctccac cagtcgcgat aattttgtct
     3121 tcatttgaca gctttcttaa aatatctgac tccacttttc gaaagctttt ttcaccgtaa
     3181 tagtgaaaat attcggcaat cgacaattgg atatgttcct caatctttgt atctaaatct
     3241 acatactctt tttgtaaaca ttgagctaac cctttaccga ttgttgtttt tccagcgccc
     3301 atgaaaccaa tcagcaaaat gctagccatg agcttctcct cctgacacaa gttctgctaa
     3361 atcgtcaaaa aatgccggat aagagattga aacagcttca gctccttcta gttcgcaagg
     3421 tccatcagct atcaaagcag ctacttgcag catcataccg attcgatgat cgcctctgct
     3481 ggacactttt gcgccatgca gaggtgtcgg cccatggatg atcagaccgt ctgctgtcgc
     3541 ttttatcttt gctcccattt tctgtaattc ttctgccacc gcatcaattc tgttggtttc
     3601 ttttactttt aattcttctg cgtctttgat gatcgtgatt ccttctgctt gagtagccac
     3661 taaagctaga atgggcaatt catcaatcag acgcggaatg atttctccac caatcgttgc
     3721 tttcttcaaa tgactcgtct tgacacttaa atcagccgat tggttctgtt cattgtgatt
     3781 cgtctgggta atcgctgcgc ccatctcctc caacacatct aagataccag ttcttgttgg
     3841 attgaccccg acatttttta acaacagttg gctttccgga acaagaagtc ctgctgctag
     3901 aaagaaagca gctgatgaaa tatcacctgg aacagttatc tgttgaccag ttaatttttg
     3961 cggtccggtc actatgatcg ttttatcttc cactgtgatc cttccgccaa attgacgaat
     4021 catttcttcc gtatggttac gggaacgttc tttttcaacg attacggatg tgccttctgc
     4081 ttgtaatgcc gcaaacagca aagcagattt gacttgcgca ctggctacag gcatattgta
     4141 tcggataggt gataaagagc gggttcctgt cacagtgatt ggtagatact ggtcattttc
     4201 ttctccttgc aagtcagcgc ccatctcgcg taaaggttcc atcactcgcc ccattggacg
     4261 tttagacaac gaagcatccc cgaacagagt agtcgtaaaa ggctgtccag ccaaaatacc
     4321 catcaataaa cgtatggtcg taccggagtt tcccatgtca attgattcgg ttggttggac
     4381 aaatgagtgg ctaccgcgac catgaatctt gatcacctct tcctcttctt cgatctcgac
     4441 acctaattgt tggaaggcat gtaaagtact cagacaatct tctgcgcgca aaaaattttg
     4501 tatagtcgtc gttccttcag caattgctcc aaacatgatg ctgcgatggg aaattgattt
     4561 atctgctggt atcctaacag tccctcttaa tccatgtatt tgttgtaata attgcattta
     4621 tccagcctcc tatttgatcc agcaatgata actggtatta gacataatga ttctttttgc
     4681 ttgtaacaaa tcctgttggt ttttaaaact gatttgcagt attcctaaaa tatcttccct
     4741 ggtctcttgg atcttcaaat taatcaaaga aactcccgct tttccgatca gtccagttac
     4801 ttctgcaata acgccaggtt catctggcac atcgataaat aaatcaaaaa aggcaggaat
     4861 cgcgccttgc ttatggacag gcaactggtc tcgactttct tttgcccgat tgaaaaaaga
     4921 aaagatttcc gattggttct cagtcatgat ccattctgct atttgtgtca tttcttgttg
     4981 ccaatctgcc aatcgttcca ataatatctg cttattgctc aacaaaatat ctgtccacat
     5041 gacaggatct gaggaagcga tcctagtgat atctcgaaag cctcctgctg ccagttgttt
     5101 ggctcgcgga tactcttgat tgaattgttc tgcctgattg actaagccag ctgccagaat
     5161 atgtggaaaa tgacttagca ttcctgttat acggtcatgt tctcttgctg taagagttac
     5221 atattttgct ttggttccgc aaaatagttc ttgcagtttt tcaacatctt ttttcgtctt
     5281 ttccaaaggt gtaaagatgt aataggcatt ttcaaatagt ttagcatctg ctgcctgtat
     5341 acctgattta tgagaaccag ccattggatg tccaccgaca aaccgaagat ttttctgctc
     5401 agcggatgtc acgacttgct gcttcgtact gctgacatcc gtaatgatga cgtgatcaga
     5461 caagttgatt ctttcaagga catcaagata agctaaggtt gtacggacgg gaacggctaa
     5521 taagataacg tctgcttgtt ctgcacctgt ttcaaaatca cttgcaacgt aatcaacgat
     5581 ctgctgttct actgcttgct cacgggtttt tgactgacta tcccaaccaa ctactatcag
     5641 ttctggattg gtctgacgaa tacaaagtgc catagaagca ccaatcagtc caagccccac
     5701 gataaaaaca tgttgtgcca tcttatttgc ccccttttta gtaatgtttc aagtagtcac
     5761 ggtactcctt cactgcagct ttcaactcaa caagcgaatc acttgggaat tttgacaata
     5821 gctctgtcgc taccacagtg gctacaacat tttccgcaac gacgctagct gcaggaactg
     5881 ctgtactatc cgaacgttct acacttgctt tgtaaggttc ttttgtatcg atatcaacac
     5941 tttgaagtgg cttgtacaat gtaggaatgg gtttcatgac cccgcgaatg acaagtggtt
     6001 cgccattggt cattccgcct tcgaagccgc ctagattatt ggtacgtcgg aaatagcctc
     6061 tttcttcttc ccataggatc tcatccatca cttctgagcc tggtaatgaa ccagaagtga
     6121 atccgacccc aaattctacg cctttaaagg cattgatact aaccacagct tgtgcgattt
     6181 tggcatctag cttcgtgtcc cattgtacgt agcttcctaa tccagctgga acgcctccaa
     6241 cgagcacttc tacaattcct ccgatcgtat ctccattttt ctttgtctga tcgatcaaat
     6301 cttttattct ttgctcaact gctggatcaa caactcgtac ttctgacgct tcagaaattt
     6361 ctttgatttc ttgaatcgag atatttccag gtatttctgc ttggattcca ccaagacaaa
     6421 tcacgtgtcc tgctacgatg atgtcaagtt cttccagaat tttcttggca attgcgccga
     6481 ttgctacacg catggtcgtc tctcttgcag aggaccgttc aagcacattc cgaagatctc
     6541 gatgatggta tttcataccg cctaccaaat ccgcgtgtcc tggacgcgga cgtgcaactc
     6601 gccgcagtga ttggtctttt tcaggcactt ctgctacaga catgacagtt gtccaatttt
     6661 tccaatcttt attttctacc actaaagtga caggtgaacc aattgttttg ccgtgacgga
     6721 tgccagacgt gatccgaaca cgatcttttt cgatcttcat ccttcctcct ctgccgtaac
     6781 cagcttgtct gcgagcgagt tcgtgattga tttcttcttc tgacagaggt aatcctgctg
     6841 gtagtccttc aataatggct gttaattctg gtccatggga ttctcccgca gtcatataac
     6901 gcatcttaca gtcctcctaa gtaatctttg aatgtctctg tgggaacagg aacgattttt
     6961 gcttgcccaa tcttttctag caagatgata ttcaattggc ttcctcttgc tttcttatca
     7021 tgggttatcg cgtggaataa ttcatctgga tgacttagat cgtacgtaat cggcagatgg
     7081 aatttttgaa gtatcctttc taaagcagct gtcgatccag ttggagacaa gccgattttt
     7141 tctgcatgag aagtgatggc taccattcca atagctactc cttctccatg actgactacc
     7201 ccatatcctg ctgtattttc aattgcatgg ccaattgtat gaccaaaatt taaaataagt
     7261 cgatttcctt ggtcaaagac atcttcttcc actacttttc gtttgatttc caacgtagca
     7321 gtaatgattg gaacagcatg ttccagaaga tctttttcgt ctttcagctc gttcagctgt
     7381 ttccaaagcg ttgcatctgc tatagctgct gatttgatga tttcagcgat tccttctcgt
     7441 aaacgacgta ccggcaaagt ttttagaacc tcaggatcaa tcaatacacc agctggctgg
     7501 ctaaatgttc cgacaaggtt tttcgctttg tttgtattga ctgctgtctt cccgccaata
     7561 ctagaatcta cttgtgcaag tagcgtagtc ggaatttgaa cgaaatggat cccacgcatg
     7621 aacgtcgagg ccacgaatgc tgctagatca cccaccattc ctccaccaag tgcaagtatc
     7681 ccatcgctgc gggtaaaatc attatctgct aaaaaatcgt ataactcagc tgcttgttct
     7741 aaagatttac tggtctcacc cgccggtacg attgaaagga ctggttcaaa attagcttgt
     7801 ctcaattgga acatgatttt ttctgcatat agtggagcaa cgtttgtatc agtgatcaca
     7861 gctacttttt gaggtctcca aatcgtttga agccatgatc cagcctgttc tagtgcgcct
     7921 ttttcaatat gaatatcgta tttttggtta tcaacatgta cagtaagcat tcgtttcact
     7981 tctttctttt aaaaagctgg aattaatcga gtgtctgaat cttttccatt gcttctttca
     8041 tgatcgcaac ttctttcatc atgcgtgagt aagtcttttc attcaacgat tggggaccgt
     8101 ctgaccaagc atttgcagga tcaggatgga tctctacgat catgccatct gctccgcttg
     8161 ccacacccgc acgagccatt ggtggtacaa gttcccaaat tcctgtacca tgacttggat
     8221 caacaatcac agggaaatga gttaattttt tcatcaatgg gacagcactt aaatcaaacg
     8281 tattacgtgt cgctgtttcg taagtccgaa tcccacgttc gataaaaatg acaggagatt
     8341 tgtcttcgac tgcaatgtat tctgcagcat taagccattc attgatcgta ccggaaattc
     8401 cacgtttcaa tccaacaggt ttacctgttt taccgacagc agatagcagt ttaaaatttt
     8461 gcatattacg tgcgccaatc tgtaggatat cgctgtactc agccaccata tcgatatgcc
     8521 cttcatccat cacttcagta atcactttca ttccaaattc atcagccgct tgacggatgt
     8581 atttcaatcc ttcttcttct aaaccttgga aagcatatgg agaagtacgt ggtttgaagg
     8641 caccacctcg cagaattttt gcgcccccgg ctttggccat tcgcgcacat tctctgattt
     8701 ggtctaatcc ttcgatagaa caaggaccag ccatcgtcac gaaactgccg tcaccaattt
     8761 ttactccgtc tacatccacg actgtattgc caggatggaa ttctcgagaa gtcaatttgt
     8821 atgtgtttaa aatacgcaca gcattttcta ctccttcata gcgtgtaaat gctccttctt
     8881 gtaaacttcg cgtatcacct tttagtccaa tcactactcg ttctgttcct tgatcgattg
     8941 agactttgaa tccttctttt tcgatatgat cgacgacttt ttttatttgt tcttccgttg
     9001 cttctttttt cataattact atcattgttt ttcccgcttt cttttgttta cttatctatc
     9061 ttggctgatt ttctctactt tttcaaggtg gttttacatt aattcctact aaatgaccgt
     9121 gtcctgttgt tctcattttc gctccttctt tcctacttat gacccagata atcaacaaaa
     9181 aaagatgtcc ctgtaggaaa ttgcctctac agtgaacatc ttcaacgagc cttaaaaagc
     9241 gctgcaaaaa tataaaatag ccactataga tgaatttctc tacgtggctg taagtcgtgt
     9301 ttaaaaatct ttagccatca tagatacaaa cctggtttgt ttgtacccac gaagtcatga
     9361 atacaaacct atctaaaata gctaaagtaa tacgtattca gttttgtaag ttttctagat
     9421 ttcataaaaa atcgctccaa actgatgtaa gaattgtacc tagtatagac ataaaaaaat
     9481 cgactgtcaa tcatttttat gaaacttttt ttaattttct gatagttaac tttgtttttc
     9541 agaaaaataa caattggttt tattgaagaa aatagtcatg aacaaaagta tctgagaact
     9601 tttttactct cttgttcatg acatatagaa taaagcagct ttgtcttgta aactccgttt
     9661 ttcaaataat aatctaaaga ttgctactga ataataaagc cgatttcatg gtcctcttcg
     9721 ctgctgattc ggtaaggtga ctcaacatcc gctccccagc tattgatacc cccgactcct
     9781 cttacttttg caaaaatcgt aagaaccgtt cgtctttctg gcggtagttc ttctatatgt
     9841 gttgcctgtt ccagttcttc tgctttgaat ggtaaagcgg aaaaagcaaa tggcgtatcc
     9901 tgctgttcaa atcgcaacga aaaatcttct tgatctttat ccgtattatc caacgtttga
     9961 tttcttgtta gttctaccca tttcgtttcc atatgcatgc cgcattcttg gggaacaagg
    10021 tatggggaaa cggggagtcc tgccacttta taaatacctt cgacaccacc agccatccga
    10081 tccggatatg tttcccctga taggccttca tactcaaaaa attttgcttt cgttggcata
    10141 atgaacctta aacccaatgc gggtaattcc ggtaatcctt tttgtccata ataatgcata
    10201 ttgacaagca ttttaccctc tccagcgatt tggtaggaaa ttgtcacttg ggtttttggt
    10261 actgtgttga tttccagtgt aaaaatgatt tcaaccgttt cagcgtattc attacttgaa
    10321 tattgattat ttactggagc aatcggcaaa tcgatctttt tattgtccac cagtacttct
    10381 atttctttga cttttggata caatccggct cctaaccaca taccggattt aaatccaaat
    10441 ccgctacctc tgtcattatc ggtcgttgct cgccaaaaaa ctggaagtgt ttcccggtat
    10501 agccattctt ttccgttttt attgagcgat tccagtccgc ctcttgtata agaaaaaata
    10561 taatgcgtat tccccgattt gacacctaat gtacagtcgc cgaagacgat tgcaactttt
    10621 tccgtatcca tatgactttt atttactgta tttttcataa taatatctta cctcctgcat
    10681 ggcgggtttt tcttgtccat ctgcaaaaac gatcccattc cctgagaatt catagtcact
    10741 tggtttatcg tcaaagtcac cgccatagcg catcacttct ctgcctgtga ttggatcagt
    10801 cacttggatc gcctgatctt taaaatccca tatatagcct ccttggtaca tttcataacg
    10861 atcaagcaac gtcatgtaag aatccattcc acctaacgaa ttccccatgt catgcatata
    10921 ttcacataag atgaacggtt tttccgcttt attttcaagg tagtcaatga tctcttctgg
    10981 tggcgcatac atgcagcttt ttacatctga aatcgaatct tcgaatgctg gatttggaaa
    11041 attcccttca taatggacaa gtcgatcggg gtctactttt ttgaagtaat cgttcatttg
    11101 tcgaatgttt tcttccgcat aagattcatt tccaagagac caaaaaagaa tacttggatg
    11161 gttttttaat gtttcgaaat tcgtttttgc tcgatcaaga acagccgcct gccactgagg
    11221 tactgcacct ggtacgttgt aagaaggctc aaatgcgccc attttttgcc atgagccatg
    11281 ggattcgagg ttcgtttccg ccatcacatg gattcctgct tggtcgcata aataatacca
    11341 agtgatctgg ttggggtaat gagatgtccg tacgccgttg atctttgcat tttttatgat
    11401 agccaaatct ttttccatat cttctatagt gatggcgcgt ccttttttcg gatgccactc
    11461 atgtcgattt accccgttga taatcatccg ttttccattg aagtagatga ttttatcttt
    11521 gatttcgatt ttacgaaaac cgaaggaata gtcaatatac tccgttactc ttttttcttc
    11581 gtctatcgtc tccaattcaa gcttatataa attgggctga aaatgccccc acagtgccac
    11641 attttcaaat ccatcgatgc gaatcgtcat ttgctctttt aacggatatt gctgttgata
    11701 gatttccttc ccatcaggat ctagtatcgc tacattcagc tgactgtttt tggctacttg
    11761 ctcaaaagac aaatctactt caagtttgcc attttgacat ttgtcatcta agcgaggttt
    11821 gatccaaaga tcttctaaat ggttttgtcc tcgagcaact aagaagacat ctctgaagat
    11881 cccaaaaaat cggaaaaagt cctgatcttc caagaatgca gctgtacttc ttttgtaaac
    11941 ctccacagct agaatatttt cttcttccaa ataaggtgtt aaatcaaatt cagacggagt
    12001 gaacgaatct tcggcatacc cgataaaatg accattcaac caaataaaca ttgcttgttc
    12061 tacaccagca aaatgaatcg agatttgttt tccctttaga ccttcttcta atcgaaaagt
    12121 cgtcaaatac gaaccaaccg gattgtcttt agcagctgaa aagatccctt ccgcctcttt
    12181 ctcagggctt gtcgtgaaag ggggacggcg aaatacatgt ccctcccacg gatacatcgt
    12241 attgatgtaa tggatcttgt cataatttgc taattcaata tgactaggaa cagtgatttc
    12301 atcaaaagaa caggcatcaa aatctttttt ataaaatgtt tttggtcgta ccgaaggatt
    12361 tggcgaataa caaaaacgcc atgatccatt taaagactgt ttaagggagg atgtggtttc
    12421 tacttcttcc cttgttgcat aacaaacatg atcgctatgt gcatttgatt ggttcactct
    12481 aaaaacttgt ggatcatcta accattttat atttgctttc atactttttt ccttctctct
    12541 cataactttt tgaaatgaag cagttctgtt tggaaatcac cttgaaaatc ggggaagtaa
    12601 agtccaactg tcatcaattc ggcccccgaa aatatccgct tcgaggtctg ttcctgataa
    12661 agtgcctcat catctaaccc catcagatat acttcatgga acgctggttg agctgaagct
    12721 agtatcctcc ctaaaaacac aatagcttca tcttgtttag gagacacaaa catccatgcg
    12781 gcaatatttt cttcaaaagg actcgccaaa cgataataat ggccatactg gatcaccgga
    12841 cgaatcgttt gataggatat aatttggtct tttacttgct ttttttcttc aggagacagc
    12901 tttgtcaaat ccagttcata accaaaaaca gcgctcatag ctgtttctcc tcttgttttc
    12961 aacgaagtag atctgtcggt ctgatgattt ggtacagctg atacatgagc tgtgatggac
    13021 gaaatcggat aagcaaggct tgttccatat tggattttca tacgctccac tgcatccgtg
    13081 ttatcacttg tccatgactg cggcatataa taaataaacc cggcatcaaa ccgtccacct
    13141 ccaccagaac agccttccca taagatttcc ggataatcag ttgtcaaatg ttcaagtagt
    13201 tcataaagcc cgagcatata acgatgcgct acttctcctt gtctctgtgg gtcaagggta
    13261 atcgaataga catctgaaag cgaacggttc atatcccatt tgatgtagtc aagaggaatc
    13321 gtatctaaaa tctttctcat ttgtttctca atcgtctgcc gaacatctaa ccttgtaaaa
    13381 tccagtacat gttgtgatct ggaagcagaa ggcattctac ctggctcctg cataagaaaa
    13441 tcaggatgtg ttcgatacag ttcagaatca accgagatca tttcaggttc aaaccataaa
    13501 ccaaatttca atcctttgct atgagcataa tctgctattt cacgtaatcc atttgtcaac
    13561 ttgccttcat actcgaacca gtctcctaat gaagaattgt ccgcatctct ttttccaaac
    13621 cagccatcat ctaatacgaa catttcgatg cctagctcct ttgcttcatc aatgatcgcc
    13681 ttgatttttt cactattgaa gtcaaagtaa gtggcttccc agttattgac cagaatcggc
    13741 cgttcagcaa attgatgacg acctcttgcg attctttcac gtagcaactc atggtggatc
    13801 tgactcattt tgttcaatcc ctgacttgag taagaaagga tcatttcagg tgtttgaaaa
    13861 gactggcctg cattcaattc ccacgaaaaa cgatggctgt tgatcccacc gacgactctc
    13921 aattgattga tctgatcttt ttcaagttcg aaagaatggt tgccggaata aacaaattga
    13981 agtccgatcg cttctccagt attttctgtc gtatgatgat gaactaaagc aataaagtta
    14041 ttcatatggt gactgctcgt tcctcgacgg ctttcaaata cttttgttcc agataaaaca
    14101 gattgccgtg aaatctgtct ttcattgaca tgtgctcctg gcaaagcaat gacttcatca
    14161 aatcgcctag tatgggcaaa gtctagctgg aaactagccg ctttttctag tttgattgtt
    14221 tctccggttt catttcttat ctttacagat cgtgtgatca ctgctctatc agtaaatatg
    14281 gtatagaaca aatcgaaata aatcgctgtt tctctatcct taagtgaaat caccaacgtt
    14341 tgtgcctctg acttgtccat cacataagtt tgaggcaagc cttcgatctc tggcttccca
    14401 tctgtaatat aatggctgtc atatctcaga tccagtaagt ctgatccatt cttgcgctga
    14461 atgatcgatg cgggcgttcg aaagtccatg ctgccatgag aagagtattc ttgcggtagt
    14521 gtatctttcg acagagaccg gtcaggattt aagggaacat ttcctgaaaa tccacgatct
    14581 cttcggggat aatttttatt gtctttgtac tgcttgactg gtttgccaaa ataaatatgc
    14641 gccaatacat tgctttcttc tatctttatc agataagaaa gaaatgtatt tcgtaaatgg
    14701 aagactcggc tcttttcatc aaataagatg aaatttttat ctgtttttct atgcgtaata
    14761 tccatcattt cactcccaac aaaacggaaa ccgtttactt ttttttataa ttcctgtata
    14821 ctgtttacta aacaattttg tcaataaaaa ttttttattt ttttgaggag tgtgtaaaaa
    14881 tggttggaat tagagatgtc gcacgaaagg caaatgtctc tcctgctaca gtttcccgtg
    14941 tgttgaataa cgatcagacg atccatgtgg ctcagactac tcggcaacgg atagtagagg
    15001 cagctgctgc gttggattat gacatcagta ctcgtaaata tatcaaaaag agaatgcctt
    15061 cgattggtgt gatctctacg atcggcaaag cgagcgaaga acaggatatc tattacaaac
    15121 atttgcgagt agggatggaa gaagaagctc gacgtctgca tttagggatg aatcgaatct
    15181 ataatctatc tgataatcct aaacaatggg aagatctaga tcagttaggt gcggtgatcg
    15241 ttgttgggac tgttacgaaa gaatcgatta ccgccttgtt aaaacaaaac atgcaaatag
    15301 tcgtcgtgga taaccctgac atccagcaag aggtcgatat ggtgtatgca gatcttgaac
    15361 ggatgactaa aaccgtactg gaattgttct tagaaaatgg tcataaaaga atagcctata
    15421 tcgggggata taaagtcgat atggatgaat tcggtgggaa gcagatttct ataaatgaaa
    15481 agaggatgcg tgcctatcag cattttatga tcgatcatca cttagaaaaa tatatgtctt
    15541 atcatctagg tggctggaca gaaaaacaag gtgaggtact tgcgactaat ctattagaaa
    15601 atgaatcccc tcttcctact gccattcttg tcgggagcga tccaatggca attggtgtct
    15661 atcgggcatt gaaacaaaaa aatatccaaa ttggagaaga gattgttgta gcaagctttg
    15721 ataatatcga gacaatcgca aacctctccc ctggcttgac cagtgttcaa atcaatgcga
    15781 aatcaattgg gcaagcagct gttcgaatgg cattggagcg aattgacggt atacgggacg
    15841 aaccaatcat tttgacttat cctgcacgat tgattgttag ggaaagtttt atcccaagaa
    15901 caaaaaggta ttgaaagaga ggttgtgaaa agccgcttcg tttcttcata ctcaaaacga
    15961 aacggctttt tcacaacctc ttacttatac ttattcacaa aatccaatgt ctgctggtaa
    16021 caattttgcg attcttttag cgtgtaatca aattggtatt catgggtaat ctcttttttt
    16081 gtatctgtat aaaacaagga ttgcacgggt acctttaatt ctgtcaaccg attttctaat
    16141 gcttgacctt gctcctggaa tgagtatgca tttccgtcag ttatatacgt tggcggaaat
    16201 tccttagaaa catggtcagc cacactagct tctttcaatt gctcactcgt tttccaatct
    16261 tttgttccaa tcaacgacca cgcaacggtt ttgacgaaaa acttcataaa tcgatcatcc
    16321 gaatgctgct gtgctgttag cttcaaatca acaggtccgc aataagaaat ggttcctttc
    16381 agactatctt ttggaagtag ctgtttgatt ttcatttgtt tagcatacgc atcattcgtt
    16441 tgtatagctg catattgcaa tgcgatttgt gaacctgcac tatctccacc aaaaaataat
    16501 tgttccatgt ctagcaattt gtcgtctttt tcttcagcta ataaatcttt gatcagttca
    16561 ttcacttgaa gaacttgatt agggtattct gaatcaggcg ctaattcata attcatcgca
    16621 accactgcga tgttggcgtc tgaaactaat tttgtcgcaa attctttgac acccgattta
    16681 tctccgccga cgaatcctcc accatgtacc caaaatagaa caggaacagg ccccttgctg
    16741 ttttttggat agtagatgtc ataagtattc tctttatact tggactcata cgtcaaatct
    16801 gtttttttcg ccacgttttt ttctgcttga tcgaacgttt ttttatcagt gatttgaaca
    16861 gtatttgaaa acatatggtt gatcaagaat gctccaggtc tgggggaaag ctggaaggca
    16921 agaaagattg caaacgcgat cccaagaatg attccgaaga accatccgat aaatttaaga
    16981 attttctttt tcataaggct ccctcagtag ttagtattaa gcattctgat tataccatag
    17041 tgttatttcc tatcaagctc tcctagatga tttaatgatt ttccccaaac ttcttctgca
    17101 atgcttttga caaaagaaat tttttccatt gttcttcaaa caaaacattt tcttcttctg
    17161 ttgaagcaaa tccacattga ggacttaagc acaaacgatc caaaggcaga tatcgtgtcg
    17221 cttcgtagat ccggtcaatc acttgctggt gctcttccat ttcgccattt ttcgttacag
    17281 tcaaaatcta agacaactaa tttatcttca gagactttct ctaaaagaac aaaactccca
    17341 gcacgttcac tatcgtattc taaataatag gcacggacat tttcttgagt aaaataatgg
    17401 gtctgctacg tcgtcatccc ccctgatgcc gccaaaatcg aataataatt tccgcgtcaa
    17461 acatgtatat ttagtgttga atcatttgag aatatgaaaa taaaaatctt tttgatcaat
    17521 cagttaatca aattgaaata acgaaaaatc tgagacagaa tgacgttcat tctgacccag
    17581 atttgatttt gcacaactca acagtcctta ttggcaaatc gccaaaataa tgtagactaa
    17641 ctaaaaagac taagaaacaa taacaaaagt taacacttct tagtctttct ttagcacgtc
    17701 tatttattaa agattttagg gccttttctc atgtttttac gatcattctt aggtgtttcc
    17761 atttgtttgg atcggcctcc accttgtttc tttttgatca attctttcat tttttctttt
    17821 tggtccattt ttattctcct ttaacgaatg aagcgactaa ttcgatatga tgggtttgcg
    17881 ggaaaagatc tacaggctga actttcttca cggcataacc tgcttctgca aataacttag
    17941 catctcttgc aaaagttgcc ggattacatg agatatagac gattcgttct ggtgacattt
    18001 cgattgctga ttcaataaaa tgatgatcta atccttttcg tggagggtca actacgatca
    18061 cagatggttt gatccctttt tcttgccatt ttttcataac tttttctgct tttccgactt
    18121 cataatgaac attttcgatt ttattattta aagcattgaa ctgtgcatct tcaattgctt
    18181 ctggaataac ttccatccca tacaccttat ccactctgtc tgctaaagac aagccaatcg
    18241 tacctattcc tgaataagcg tcgatcacaa tgtctttttt atctaactcg gcaaactcga
    18301 tggctgtttg gtacagatac tctgcttgtt gagtatttac ttgataaaat gactttgctg
    18361 agattcgata ggtttttcct aatagctgat cttcgatata gtctctgcca tataaaactt
    18421 tttctttgtc tcctaaaatc acatttgttt tttcttcatt gatattttgg atgaccgaaa
    18481 ccacttctgg caattcttca tgaatagctt cagcaatttc cttggattta aagaattttt
    18541 ctttacgagt aactaaaacg accatcattt catgggaata atgaccacga cggataatga
    18601 tgtgacgaag ctgtccttca tttttttctt cattatatcc tcgtacttgg aaccgttgca
    18661 agatatctct gactactttg attgcttgat cgatgacagg atcttggata taaaaatctt
    18721 cgatagggac tagatcatgg ctattctttt tgtaaaaacc ggtggctaac tgtccatcga
    18781 tacggcgaac agggatctgt gctttattac ggtagccgaa tggttctgcc attccgaccg
    18841 ttggaagtac aggaacttct ggcatcttag caatcttcgc cattacatgc tctacttgtt
    18901 tttgtttgaa gacaagctgt tgttcatact tcaaatgggc taaaggtgcg atacctatgc
    18961 gaagtaatgc attgttttct acaggctgac gatcaggtga ttgtgtaata aatgtttcga
    19021 cttttccata tccaaactta ttgcctgctt ttactactag tatttctact tcttctccag
    19081 ggagtgcatt ttcgataaat aatggataac catcgatttt tgctaccccc attccttcat
    19141 aactcaagtc gacgatttcg actgtatatc gttcgttttt ctttactatt tgctgttctg
    19201 tcatattttg ctcctttaag cctatttttc aatcctactg aactctacta taaatcagct
    19261 aattacacaa ctaaaaccgg cactgacctt actacgttca gcaccggctt ttgattaatt
    19321 cttttgatta ggtgtttcgt ctgctatttt tccgtcaccg tcgatatctt catccgttaa
    19381 acgttcgact tcttttacga attctttgct gacaacctct aattcttctt catctgtacc
    19441 tgtgattgct tcatcaggaa tctgatcggt attggcaaag aactcaatgt gttgatgaag
    19501 attttggaaa tgcatcggtg cttccccgcc gtattcacca tctaagttga tcattactgg
    19561 tcgattgata tcatcttctg tttcaacgaa caaactgctt gttttggtat agattattct
    19621 tggatcatcg acatgtcgac cgccattcag catgagtgct gcaatatgca agatctcaaa
    19681 gatatttgct gtcttcacaa tgattaaaga aaacttccca tcatccaatt tggcatctgg
    19741 cgcgatctgt tcgaatcctc caacagagtt cgtcagccct aggaaaaaca tcgaagcatt
    19801 tccgatatat tccccttcat catacttcaa gcgcattttg attggcttta ctcgagggag
    19861 catctctgct cctttcgcaa gataagcaag ataaccaaaa atactcttta gttctgatgg
    19921 aacttcataa gtcaattctg tcaaatagcc acctgcagcg atattgatga agtaactgtt
    19981 atcagaaagg ccgatgtcca tttttacggt ttggtgtttt tttatcactt ctgctgctgc
    20041 tttaatatta tctctaggaa tttttaatgc tcgagcatag tcgttcgttg taccagctgg
    20101 gatgatggcc attttaggac ggtgttcaag cggagcgatt ccattaacca cttcgttgat
    20161 tgtgccatcg ccaccagctg ccactactag atcaaaacct agttctgcga ctctacatgc
    20221 ttcattcttg gctgaatctg gttctggtgt agttgcatag gcgctggctt caaatcctgc
    20281 ttcttctaat gcctgtagga tatcctccaa attttttttc aataattctt ttcccgaggt
    20341 ggggttataa attacgcgtg cttttttcat tttcagcctc tatcgtttcg ctaattcatc
    20401 tttaagtagc ttattcacga caccaggatt tgcttgtcct ttagttgctt tcatgatttg
    20461 accgactagg aagccaaccg cacgatcttt tccatttttg aaatcatcga cagattgttg
    20521 gttgttatcc aaaatttcat taatgattgg cagtagtttg ttcggatcag ataattgcac
    20581 ccaaccattt ttttcaacta cttcttgggc ttctccgcca tttgtgatca attcacggaa
    20641 gacttttttg gcgatttttg agctgatcgt tccatcggcg atcaaacgaa tcattcctgc
    20701 taagttctca ggtgtcaatt ttgtctcagc taattccagt ttctcactgt tcaagtaagc
    20761 agaaacttca cccatcaacc agttagatgc ttgcttggca tctgcaccat tttccaaaac
    20821 agcttcaaaa aaatcagaca tttcttttgt aagtgtcaat accattgcgt catactctgg
    20881 aagtccaaac tcacggatat agcgttcgcg acgagaagct ggcatctcag gcaaactagc
    20941 ttttactttt tgaatccatt cgtcatcgat cacgaatttc gggatatcag gctctgggaa
    21001 gtaacgataa tcactagacc cttctttgac acgcatcaaa actgttttat tcgttgtttc
    21061 gtcaaaacgg cgtgtttctt gttggatttc tcctcctgaa agaagaactt ttgcttgacg
    21121 tttttcttca aaagctaaac cttttttcac gaaagataaa gagttcaagt ttttcaattc
    21181 tgctttcgta ccgaactctt cttgtccata agggcgaaga gaaatattgg catcacagcg
    21241 catagagcct tcttccattt tcacatcgct gacttctgta aattggataa ttgatcgcaa
    21301 tgcttctaga taagcgtatg cttcttctgg tgaacgcata tcagcttcag aaacgatttc
    21361 gatcaaaggc gtgccttgtc ggttcaaatc aacgtaagaa taaccgccaa taccatgcat
    21421 gttttttcca gcatcttctt ctaaatggac acgttcgatc cggatttttt tctttttacc
    21481 ttctacttcg atttcgatcc atccgtcatg accgattggt tgatcaaatt gggaaatttg
    21541 atatgctttt ggattatctg ggtaaaagta atttttccgg tcaaaatgag tatctttaga
    21601 gatttcacag tttaatgcca aagctgcttt catcccgaat tccagcgcag ctttattcat
    21661 tactggcagc acgcctggat aaccccagtc gatcacgttt gtattgctgt ttggttctgc
    21721 accaaaatga gctggcgctg gagagaaaat ttttgagttg gtttttaact cgacgtggac
    21781 ttctagtcca atgactgttt caaaattcat tcgtctttcc ctcctaaaat agctggttgt
    21841 tgtttatgga attctgttgc ttgttcaaac gcatatgccg cttgatacat cgttttttca
    21901 tcaaaataat taccgatgat ctgcaatcca actggtaatc cttctgataa acctgccggt
    21961 acagacatac ctggaagtcc agccaagttg acagggatcg ttaagatgtc actcatgtac
    22021 attgtgattg gatcgttaat gttctcaccg attccgaatg caactgttgg tgaagatggc
    22081 ccgatgatca agtcataatc tgcaaagact ttttcaaaat ctcgtttgat caatgtacgg
    22141 acttgtcctg cttttttgaa gtaagcgtca taataacccg cgcttaagga gaatgtacct
    22201 aacatgatac ggcgttttac ttcttcaccg aatccttctg aacgtgagtt gacatataca
    22261 tcatctaatg atttcacatt ttcagagcga taaccgtagc ggataccatc gaatcgttgc
    22321 aaattggaac ttgcttctga tgaggcaatg atataataaa cagccacacc gtattttgaa
    22381 tgaggcaagc tgacttcttc cacaacagca cctaatgaac ggaatgtttc tgctgctttc
    22441 aatacagctt cttttacgcc aggggccaca ccttcgccta agtattcttt aggtaaagca
    22501 atcttcattc ctttgatgtc gcctgtcagt ccctctgcaa aatcaggaac tgaaacgcct
    22561 gaagaagtac cgtctttttc gtcataaccg ctgatagctg tcaatgctaa tgcattatct
    22621 ttcaccgtac gggtcattgg tccgatttgg tcaagagatg aagcaaaggc aatcaaacca
    22681 aaacgtgaga cacggccata agtaggtttc atccctacga tgccgttaaa agctgctggt
    22741 tggcggatac ttcccccagt atcactacct aaagaaactg gaatttgtcc agctgcaact
    22801 gctgctgcag aaccaccaga agagccacca ggtacttttg ttgggtccca agcatttttt
    22861 gttttcttga aataagaagt ttctgtactt ccacccatag caaattcatc catgtttagc
    22921 ttaccaacag ggatcatatc tgcttgatag attttatcca tgaccgttgc atcataaatt
    22981 ggttcaaaat tgtaaaggat cttagatgca gcggttgtca agatatcttt tgttacgata
    23041 ttatccttga taccaattgg aataccagca aggacgttgc tttcatcaat ccctttttca
    23101 tctaaagctt ttgcctgttc caatgctttt tcttcgttca atgtaatgaa tgcctcgacc
    23161 tcaggctctg tttctttgat tcgttcaaat gttgtttttg tcaaatcttg tacagtgatt
    23221 tctttcgata caagcatatg atgcagttct tctagagaac gattgtgtaa ttctgtcatt
    23281 atgcgccagc ctccccatta tcgatgattg cgggtacttt gataaagccg tcttctgttt
    23341 ccggcacatt tttcaataat tcatcgcggt tccatccagc ttgcgcccga tcttgtcgca
    23401 tcacgtttac tgtttcaacc acattcgacg taaatggaac accttccgta tctacttctt
    23461 ccagcatttc aaccatatcg atgattttac ctaattggtc ggtaaaactt gcaagttctt
    23521 catctgcgaa cgcaagtttt gctaatttgg caacgtgttt cacttgttct tcactaatcg
    23581 ccatactacc ccttctttct aaacgagtta aaaactttgc tctctatttt aacacaagag
    23641 tgccgtgtct gaaattgttt attgaaattt gtctgaaaaa actcattttt cattcttcta
    23701 ctgagcgact tttagccaat gcatctgcca tttgatcttc tgtccaaact tcgattccta
    23761 attcttgtgc tttggtcagc ttgctgccag catcttctcc tgctaccacg atatccgttt
    23821 ttttcgatac gctaccagtc actttcccgc caagattttc gatcgtctct tttgcttctt
    23881 cacgagtaaa tcgtgttagt ttaccagtaa ggactactgt tttttcttta aaaggagact
    23941 cgacttcttg caattgggca tttcgaagcc ctttgtattc gaaattgacg cctgcttgtt
    24001 ttaattcatt catcaattca tggacttctt cgttactgaa ataagtgact acactgtcgg
    24061 caatgatatc accgatcgta tcaagcgcaa taatcgactc atagtcactt ttactcaatg
    24121 tttctagatc accgaaatgt tctgctaaaa tttttgctgc tttcgctccg acatgtcgga
    24181 ttcctaaccc gaaaatcaac cgctcgaccg aattatcttt gctgttgtcg attgctgtca
    24241 aaatattatt tgctgatttt tcttttattt tgtccaacgt caataactct tcttctgtca
    24301 atttgtaaag atcagcaaca tctgctacta gttttttatc atacatctgt tctagtacgc
    24361 gcggccccaa cccatcgata ttcatcgcat ttcttgaaac aaagtggttc aaaccttctt
    24421 tcatttgagc agggcattta ggattgatgc accgtaaggc tacttcttca tccaaatgga
    24481 caagttcact tccacaaact ggacaatgtg taggcaattg gtattcttcg ctgtctttag
    24541 gtcgtttatc taacacgact tgcgaaactt ctgggatgat gtctcccgct ttataaatca
    24601 gaactgtatc tttcaagcgg atatccttca acttaatata atcaccgtta tgcaggctgg
    24661 cacggcttac tgtcgttcct gctactcgga ctggtgtcat gatagctgtt ggcgttacta
    24721 cccctgttcg accgactgtc cattcgatgt tttcgattag cgtttcaact tcttctggcg
    24781 gaaacttgta agctgctgcc catctcggtg ctttgatagt aaaaccaagt tgatcttgta
    24841 gcgagaattc attcactttg atgacgattc catcgatttc atagggcaaa tccacacgtt
    24901 tgtcatgata ttcttcaatg tatgaccaca cttcatcaat cgaatgacat agacgttttt
    24961 cccgattcgt gtggaatcca attttttcta gctcttctag cgcatcatac tgggtttttg
    25021 cttgcatagg accgaaatca gctactgtgt ataaaaaagt gtccagattt cttttcgctg
    25081 tgattttaga atctaactga cgcaaagaac cagctgcggc gttccgagga ttcgcaaaga
    25141 tatcttttcc ctctgcttct ctgtcttggt tcaattggac aaatgaccgt tttggcatga
    25201 aacattcgcc tcttacttcg atgttcattg gttcttttaa tttgattggg accgaccgga
    25261 cagtttttag gttttcagtg atgttttctc ctacagttcc atccccgcga gtcgcacctc
    25321 tcacgaaatt tccatcttca taacgcaaag aaacggaaag tccatctatt tttagttcac
    25381 agcaatagtc aactacacgt cccactgctt tttgtacacg ttgatcaaaa gctatcagct
    25441 cttctttgct gaaaacgtcg ttcaaactgt aaagcggaat atcatgagtg actttttcaa
    25501 aaccttctaa tacttttccg cctactcgtt gagtgggaga atcagacgtg atcaaatcag
    25561 gatattgttc ctcgattgct actaattctg cgtattcttt atcataaaca tagtcttcca
    25621 ctgttggttt atcttctacg tagtattcgc gagaccattg gttcagtctt gtacgaagtt
    25681 cttctgctcg tttagcagct tcgtcaatcg tcatttcatg ttccatcatt taccctccac
    25741 tactaagctt tttcaattgg cgcaaaggca gccaaaagac gttttactcc ttgacttggg
    25801 aaagccacat ctagttctag atccttcgac gtcccgctta ctcggacgac tgttcctaga
    25861 ccccattttt tgtgtttgac tttatctcca ggtttccagc tgttattttc ccctccagta
    25921 gcacttttag agggaacaac cgctgtctct ggctgtttat agctatatgc tgttttttta
    25981 gcgaatacag gcgttttttt aggcgtagga cgcatgcctt cgatttccag taactcctga
    26041 tcgatttctt ctacaaaacg agaaggtcgg ttatattgcg tccgtccata taatgttctg
    26101 gagaaagcat ttgttaaata caacgcttct tctgctcgcg tgatccccac atatgcgaga
    26161 cggcgttctt cctccagttc gctttcttcc atcaatgctc gagataaagg aaaaaccccc
    26221 tcttctagac caatcaggaa tacaactgga aattctaatc ctttggctgc atgcaaagtc
    26281 atcaatgtca cttgggaagc atcttcttct aaattgtcaa tgtcggaaac aagtgccaga
    26341 tcatttaaga agaccgttag tttttcttct ggtgcatcag cgtcttcttc attttgctgt
    26401 tcgaattgtt tgtcgaattc ttgtgtgacc gttaaaaatt cctccaagtt ttcgatgcgt
    26461 gcttgtgctt ctaatgtatt ttggattttt aagtcttcta gatatccgct acgatccaaa
    26521 acctctttcg tcaattctgt cactgtcaag tatgggatca tctgagtgac ttcttggatc
    26581 atctctccaa atgcacctaa ttgctgtcct gcttttccac cgatatttgc cagatccaca
    26641 ttttgcgctg cttcaagcag tggccattca tgaagagaag caaaactgcg tagtttttcg
    26701 atagatcctg gtccgatgcc tcgtttgggc gaattaacga tacgctcaaa actgattgaa
    26761 tcttgaggat ttaccagcac attcaaatac gctaaaatat ctttgatttc tttacgatcg
    26821 tagaacttgt gccctccaac cattttataa ggaatatttg ctttcaacag agtttcttcc
    26881 attacacgag attgtgcgtt cgtccggtac aagatggcaa agtcgccgta attccgatga
    26941 ttgcttcgaa tctcttcttg catccggtct acgataaaac gggtttcgtc tcgttcatta
    27001 tctgcacggt agtaagtgat cttgtttcct tctttgtttt ctgtccacaa gttttttggt
    27061 tttcgattgc tattgttttc aatgacttgg tttgctgcgc taaggatgtt tttcgtggag
    27121 cgatagtttt gttctagcaa aattactgca gcatctggat aatctttttc aaaatccaag
    27181 atgttctgca tatctgcacc gcgccagccg taaatacttt gatctgcatc tcccacgacg
    27241 cacaggttcc taaatctacc tgccaataaa ttgactagcg tatactgtgc gtgatttgta
    27301 tcttggtact catctacatg aatataatgg aatttgtttt gataatacgt gagtgaatca
    27361 ggatgttctt caaataatcg aatcgtattc atgatcaggt cgtcaaagtc catacattga
    27421 ttatattgaa gctctttttg gtaagcagca taacattttg ccgcaatctc ttcgtaataa
    27481 ctgccttgca tttttgcaaa atcctgaggg gtctgcaggc tgttttttgc ttgagagatt
    27541 gttcctaata tacttcgagg atcatatttt ttcggatcaa tgttcagttc ttttagtatc
    27601 cgtttcatca aggtcagctg ttcagaagaa tcgatgattg taaagttccg gttatacccg
    27661 ataaaatcaa catctcttct taaaatacgc acacacatcg agtgaaaagt cgatacccag
    27721 acatcttcgc ctccagatgc gagaatcgca ttgacacgtt ctttcatttc ttttgcagcc
    27781 ttattggtaa aagtaatcgc taggatgttc caaggattga cttctttttc ctcaatcaaa
    27841 taggcaatgc ggtgtgtcag cactctcgtc tttccacttc ctgcacctgc cattagcagt
    27901 aatggtccgt cagtgtgaag aacagcttct ttctgacggg ggttcatccc gtttaataat
    27961 tcagctttgg atgacattaa caacatcctt tcttttatca atcttgttaa ttatagcatt
    28021 ttcttggctt tcattaaact agctagttca aaatcatttg tttcttttta tggatttttc
    28081 cttgtcaatt cgttgatttc gcgctaaatt aaaagaaagc gaggcgtttg aatggaaaaa
    28141 aaaggaaaaa tcaagaaatt agataagact cagatatatt ttattctaaa aggaatattt
    28201 gttggactgc tgacaggaat cgtcgttagc ctgtttcgat tatctatcga aaagctaagc
    28261 gatttagttc gaagtatcta tgaaatgagt cgggaacagc cgatttactt aattggccta
    28321 gctatttgct gcatccttgc agcatttttc gtgggttatc tggtcaaaaa tgaaccggat
    28381 atcaagggaa gcgggattcc acaagtagag ggacagcttc gcggggaatt atcaatgaac
    28441 tggttctctg ttttatggaa aaagttcatt ggcggtgtac tttcagttgg tgcgggcctt
    28501 tttctaggta gagaaggacc ttctatacag cttggcgcat ccattggaca aggagctgga
    28561 caattgtttc ggagtccatc ttcagaagaa aagattttaa tttctagcgg tgcaagtagc
    28621 ggacttgcag cagcattcaa tgctcctatc gcaggattac tctttgtttt agaagaaatc
    28681 catcactcct tttctccact tgtttggctg acatcatttg cttcagcaat cactgctaac
    28741 ttcgtctctc tttacttttt cggcttgaga cctgttttat atctaggtga ccttccttct
    28801 ttgccgttga aatattatgg ttccttagtg atcttaggag tacttctagg catcttaggt
    28861 tttatttatc agaatgtctt gctggctttg ccaaaatttt acaaccgatt gcctttacca
    28921 gcttattttc acgggttcgt tcctttcttg ctgattttgc caattggtta tttatggcct
    28981 agtactctag gcggaggcaa tcaaatcgtt ttagcttttg gacatgcttc cttgccaatc
    29041 attatgatta tcggtttgtt tgttcttcga ttcgtttttt ccatgatttc ttacggtggg
    29101 ggtcttccag gggggatttt ccttccgata ttgacattgg gggctttaat cggtagcttt
    29161 tatggaaaca ttatggttga tttcgggatg gatccaatct acatcaagga ttttgtcgtt
    29221 attgccatgg ctggttattt cacagcgatt ggaaaagcac cgctgacagc aattatttta
    29281 gtgacagaaa tggttggctc tcttaatcat ctgatgcctt taggattggc tgctcttgtt
    29341 gcttatatcg tcaatgacct tctcggcggt aatccaattt acgaatcatt attggaacgt
    29401 ctacttggaa atactcagac cgcctcacta aaaggtgcaa ggacaacttt tgattttcca
    29461 gtaacggcag agagttcttt agacggatta atggtacgag acttcaattg gcctaaaaat
    29521 atgctgctaa tctctatacg cagaggaaat caggaaatct tgactcacgg tgatacgatc
    29581 atgaatgtag gagatatttt ggttatcttg actgatgaag caaacttgcc aagaatcaag
    29641 caggaaatcg aggctaaatc ttctatcaca aatttgaagc aatcatttta acgaacatgg
    29701 aaaaactatt ttacaacaac tattcatcta cactacttga ttctatatga ttctataaaa
    29761 aaagaagagg ctgggaaaa
//
LOCUS       DACGEU010000027        29584 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.027, whole genome shotgun sequence.
ACCESSION   DACGEU010000027 DACGEU010000000
VERSION     DACGEU010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29584)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29584)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29584
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.027"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            250..813
                     /locus_tag="IXR40_001141"
     CDS             250..813
                     /locus_tag="IXR40_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361003.1"
                     /translation="MTAIYKALKNSNVSEYVKSRVLNNNLDYILENGVADLISKLSDP
                     IDIDHLVVWQDGTLEVSIYGEFYSRNKVTTFKNSISGREDLKGINKNSKFYRTNKELL
                     EKISKRVFELVNPFSKTRSKELFGIFYDGFSAKSNVEKFFYFNDSAYIAVKDSKRIPE
                     ATLEYLEPIKLSVFYSLYEKEIADEAV"
     gene            800..1684
                     /locus_tag="IXR40_001142"
     CDS             800..1684
                     /locus_tag="IXR40_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraA"
                     /protein_id="HAQ4361004.1"
                     /translation="MKRFKGSRMSKKIGKESLSLGLKKEIFKFKNMYSEPEFRLIFQL
                     DIVRGLKISFSCLGYLVWLFIARVGWSNAYSFYKLFAGTDRLKESLEVKEALNILGSL
                     AFSLFIFALFILQVGKIMMSTNDNYINYLKPFQKGIKIICRQGTVLFLLSLYEHEIHF
                     QNYYNTTTKLGAFLLLYLVSNIAEKMLFKHIVKQVFSDIKKESYCLKTPYGNLKNVEL
                     FLFKMDSKWDKYIYRSKEVFLTGSYNETLQESLYDTGAIFNNEPMVLKDFFGDYELVW
                     NPKQLSEQGAENEFAEVH"
     gene            2181..2435
                     /locus_tag="IXR40_001143"
     CDS             2181..2435
                     /locus_tag="IXR40_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361005.1"
                     /translation="MYNVGDQIDEIVKIGNVKLDKSKYCISETEIIFNTELGYILIWK
                     LPFPKDEETLKKINTLKIRYCVYEVIDKNTYVINQVKVMG"
     gene            2831..4432
                     /locus_tag="IXR40_001144"
     CDS             2831..4432
                     /locus_tag="IXR40_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HAQ4361006.1"
                     /translation="MLNSCEYADVLAKILKNGIKQFNSKNLVAFKKNSNKIGAIAGFT
                     SKTNMIKTKGLIYRSIDRVLEDSDVLTHWTPNVYSWLGGGENKTIFGHKEANLIQINT
                     FVADIDYPVGEKKTDLNLLVLYLLEEGLLPTLIVDTPKGYHCYFLIQNYNQETDSFDK
                     ASYISNSNDFKSLRVAKRISENIRKSIQNRLPQVDMGCNHFGIFRFPTKKNIVHYEPN
                     FVDTFEGYLKWSKDFEEKEYALKRSNLSLLAPNSTGKKGSKRQIDTKWYDFLIHTDIA
                     EGDRNKTVFTLALACKSSGLSIGECMDQLDQLQFNNDLSYSEVERTIRSAYRGDYKGA
                     KSSYVNEIIENYATPTEFEKYSINVNRQAVKRKGNRVDPSNWVKFAKPREERKYSHFE
                     ESKADLLAYLERKQRSLKKNELFLSVSMGTISEETQIPVSTLKVILKELRTANTVILQ
                     TSRGRYGSTKIATSKFVEAKILSTVIQNKKDKQVFVLELLGTANSHVETILRRYEDKT
                     VPFHANILKEREKSKHAPIRGANTG"
     gene            4666..4965
                     /locus_tag="IXR40_001145"
     CDS             4666..4965
                     /locus_tag="IXR40_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HAQ4361007.1"
                     /translation="MVIKKYVYSHPINVFIIGKLGLSVEVFCELYGFKQGTLSSWITR
                     EREVADLPISFLYALSLASGGNMNEVYDCLCEYEKEYKEYLKISAPKRNKKYIED"
     gene            5100..5477
                     /locus_tag="IXR40_001146"
     CDS             5100..5477
                     /locus_tag="IXR40_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
                     /protein_id="HAQ4361008.1"
                     /translation="MNIDGIYNESDFKKGIVDIDRKEYLFPDEIGLFKIVGETVCRYW
                     GKKGNIILLVDTIEGRKLKFSFWSNTKYCCEPVPKREVDVAKESVRFLPDRSKITLIC
                     ERTSNAKFTRIRDILLSTTSSQS"
     gene            5526..7889
                     /locus_tag="IXR40_001147"
     CDS             5526..7889
                     /locus_tag="IXR40_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
                     /protein_id="HAQ4361009.1"
                     /translation="MAVVILAEKPDQGAKFASALAGKKLSKKSGKYEFKSEIFGDTIV
                     TWGIGHLVGLSLPEKYEWLPNKDKWHLDNLPFLPKFNELKYEVSKGKNQQFSIVKSCL
                     ENADEIIIATDPDREGENIAYNIFKLCKQSIFNKPIKRLWINSLVQKEIIKGFKNLRN
                     SEETISYFKEANARQIADYLVGMNYTELYSLKLQEKGISGVVSLGRVQTPVNTLVVEN
                     DLAIRNFRPEKYKTIECHTTDKQPKAIFKNSLEYFKLEKFEEDTKKFGLDSASTGIIK
                     KIEVSKKQTEPQKLFSLGGIQEYANKKWKYSAKKTDKIIQSLYDRGYLSYPRTDSELI
                     TTNEFEYLKANLDVYKSVLGISIDTPCLEPKKRFVDNDKVLEHYALIPTMDIPDIANL
                     TLDEKNIYEIVTRRACLMFAEPYKYENTKVTLDVNGLEFTTSGNVPISLGWKQVDTNL
                     DESDDKEETLPKFHEQETINIDIRFIDKLTKEPKRLTEGKLLGKTGIMAKLGLGTPAT
                     RSNIVDTLLNREYIKIENTNVYPTPKGYLLWDLTKNKDLLIGKPENTAIWEESLGKIA
                     QGSYTQEAFLRNIYNYINKTVSDLKKVEFTSDYLEKTVNQNKFDIGSYQVEEKKKVYS
                     ILNITSGEQFVIFKNISGKAINKKVLQELLLNNRTDKVLSGFKSKEGKAFNARLLFDP
                     NVMKVVMEFEKNSPKGDKKSKHDTVNGYEIVEKAKVFEIKELATGESFIFYKNNSGKT
                     LSSKTVKELLENGKTKEKVTGFISKDNKKYSAYLVFDNKNKVIKKEF"
     gene            8207..8806
                     /locus_tag="IXR40_001148"
     CDS             8207..8806
                     /locus_tag="IXR40_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361010.1"
                     /translation="MNLKNTNSNKSTLYVISDDYINKLKKVDYRVQNNYREQRLYFKS
                     NLKISNKNEEINYYVPLASAKENQRSLTNKSVFKIYGDREEKDFLGVLHINNMIPVPK
                     DCAKVWTPNSPNVDEKYKMLVIKQAKYLKLHESEINESCELLYNSKLGKLDPSYFKKN
                     RKEVITYQKIMTNVESLEAVSIAESQRNIHVQTQSIDVE"
     gene            8918..9142
                     /locus_tag="IXR40_001149"
     CDS             8918..9142
                     /locus_tag="IXR40_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361011.1"
                     /translation="MISMARPRKYNTEEERKEAMKKARKKWVEKNQETIAYIRAKSFA
                     KKFIEMSEDEDIELLEKWLEDRKNNGQNDE"
     gene            9494..9730
                     /locus_tag="IXR40_001150"
     CDS             9494..9730
                     /locus_tag="IXR40_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361012.1"
                     /translation="MLSDYKEELKLIENRVLGFVECKDNLDDTLEVLESIIFNTKVLD
                     LKAINGDMTTHIILDEISAKEIGETLIAWANKEL"
     gene            9810..10664
                     /locus_tag="IXR40_001151"
     CDS             9810..10664
                     /locus_tag="IXR40_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAQ4361013.1"
                     /translation="MMKSNFLGYVIAINMFKGGVGKSTLTQLMADILSARGFKVLVID
                     VDPQGTVTKKFQRQYDLKVVGKMTLFEAVINMSFLDCISPVKENLDIVLGSEQMSRFT
                     KVLRDMWRSTGFTDEGEEVFWNLFNYMIGNDNLRDQYDFILFDTIPTVSEFTDNVYVA
                     SDFLVIPTQTEQDSIDNLHSTVTNYQTAVKEVNGDLEILGIVPYLVDTKLKTGLELLS
                     ELQEEYGDLVYSHIVSERGVIKRWGREGLNKSIPHSKTAYSMYVDIVEETLVRLEKAT
                     GENILERV"
     gene            10677..11114
                     /locus_tag="IXR40_001152"
     CDS             10677..11114
                     /locus_tag="IXR40_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361014.1"
                     /translation="MMSKTKKVTSAGSNGSGNPFGIKSGSGGFNIGQQMLKGKAGIKS
                     TGDKRKSVRVPVELYDEVVKDLSYGAKYSLMTEILALFLKEFETHGNSIVTDFGKLKT
                     RPVKISEEAFKVLKVIKFETDQSNTNIIASALTWYLDKRKGKA"
     gene            11434..11877
                     /locus_tag="IXR40_001153"
     CDS             11434..11877
                     /locus_tag="IXR40_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HAQ4361015.1"
                     /translation="MQILEDIKIYWKRIIGYTLVLLVVNLFLSMIALVFVNQRKDNVT
                     ELVTFISFFISGIFAPFFEETLMRGIIQNQLELKTNLSTRSIYIIVAILFSLSHLNLY
                     FIPYFMTSLILSFVYDNSDKRLIVPVTIHCFYNLIVILLSVVFYT"
     gene            12022..12345
                     /locus_tag="IXR40_001154"
     CDS             12022..12345
                     /locus_tag="IXR40_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361016.1"
                     /translation="MARSRIAKIEQTKKDKKISKNKTKFFKAEDVKRIAWSVKTFDED
                     RYVKVSMNGLFVQLGNFSNFKTIDELYPEIRNIVDSKGLIVAKRKSRNSGLAYCKNKG
                     IMIPA"
     gene            12763..16392
                     /locus_tag="IXR40_001155"
     CDS             12763..16392
                     /locus_tag="IXR40_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361017.1"
                     /translation="MKKLKLISIALFSLITMSTARQSIVSAEGTSTKAVVEESGDKKV
                     AIDDKVKNEAEKATVVQGADGLMYVVVDENDPEKLLEAESPLKNQQENTGAVEVGVDE
                     KRQEKADKANEKVKNFDDIDYNDISSLQSALNDPKFPFLSEDELNEKLQKTKNTFESE
                     ALMKKTRGYFSQRILELSNNLNDVPKRAKVSRHALVSNRASQVSETRINPPNGYPWVI
                     YLIRSNGYSYTENYAIRRTIDGKEAFCLQAGVQATNTYTGSTSGYLSNSQREMISSIL
                     SAYKELGGWANNDAGKQRWIATQMLVWENSNEKPKSITVTPNWKNGATKWKNDLVARA
                     NAIRVRTKWDSTSKTVDEGDKATFKVTNTYGDHNLHVKSVSGGGKATISNGTLTVDTT
                     GATGNKITVDMIKGSHPSDAHPTTVWSNGSYQKLVTGSFYISTSVTVNVKRKGTVEVL
                     KVDSETKKPLSGATFRFSYSGKTKDVTTDSNGKAKLTERLKAGTVVKVKEIKAPNGYQ
                     LDSSEFSITVKENQNVTTTRTNKKSTGSVEIEKIGDLDGLGLPNVVFTIYNSDNKVVK
                     DNLKTDSNGKIKVDELQFGKYYAVEKQGVTGYDPDGKKYNFEISQDTPFTKPAKVKVT
                     NIYEVSISEKVSDMNESQVLKNNWSADPNDYLQYDITTGNLKKSGERNVQSFIIEGFY
                     DNKNVDVSKSEVYVGSTNVTNSFDINNDTNNGKVIAKAKTSVLTNNDFYNKSYNLRIT
                     MKIKKSTLENTEKQKNLTIVKNSKVTVGSKISKSASSNDVETVLYSRKVTINHIDEKD
                     KHLLKQDIDYKYDGETYEYKPRTDLFDKDGNNYKSDVIHKGKIDGKDIVLNTPYHIPV
                     LSVNVDRIQIDTARAVKNGYLPTKIELSKKEEYEKELEKIVFKVKITDIDNNKVVYDE
                     NFKYKEFNSHMSLDLPTEYLTKNKKINYSVDILLVDNPDKNKFETETKDLRTIGYTSS
                     EKVLTNKDMTNNQVNYSAVVRTVKERENNNPVKEFNESINYKFTDSTKTKTGYGISVD
                     LEPTYRNEIGKQIDMKVYSYPMNELIDSKIDEIYQSGGKETEVKMDRLKNDGKVESGI
                     STQNLSFQFPHMNIERKTGNIYADSQRNDESIKYELIDGGRKLYVPIWCDLGNYSIAI
                     KSSNFGGNYISLDMNQNIDVYAYMYATIDSETKKDDELLLEPVYPESTLPDGWSKNEI
                     DWLNK"
     gene            16452..16814
                     /locus_tag="IXR40_001156"
     CDS             16452..16814
                     /locus_tag="IXR40_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361018.1"
                     /translation="MRVQSYGNSVFDVKREFQDSRRKTKKLIAYFILSAIVFYIVKFV
                     LELNSIVFTDMVHKMLNGEPINFNFDYMLEKAQSNQIVAFIVSIYYFIEKSIFSLKDF
                     FFEMLTKLTTFYNKISKN"
     gene            17048..17470
                     /locus_tag="IXR40_001157"
     CDS             17048..17470
                     /locus_tag="IXR40_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361019.1"
                     /translation="MIYVAFFLDGSDVMLRDMPKMILLMFVGFFLILVIAYYSLNGYT
                     QDSSVKGMQETLRTTAIANRDDSIRVEKGRFALIKSDFEKDFKEKFGKSKNLNNETAD
                     YKFDYLTDGKDGIKAIKVKVESGSKEYQATCILNVAND"
     gene            17482..18897
                     /gene="cpaF"
                     /locus_tag="IXR40_001158"
     CDS             17482..18897
                     /gene="cpaF"
                     /locus_tag="IXR40_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component"
                     /protein_id="HAQ4361020.1"
                     /translation="MRVVEEKKISPKIEETPKSKINIASIIKKNGIKENSEAIEGNLD
                     FLTKLLEEDSGNYEPPIEDAKLNMIRDDLTRNYSQEVLQALTDDEIRRKLVQVVLKEH
                     GTFFKKDKEVAEYVVRECIGTGIIERIMTNDEITDVGWNGSQLSIETNSNKWLFDGDK
                     LNITQEYIERVISKYAVVNDRAFNSGNPIMDGMFKNVRISATHIDNSPDGSTFSMRVA
                     RPRLALNKENFEDFAPDYILELFEKMMKTKANICISGETGTGKTELQKLLLSFIDNHD
                     RMIMIEDVQETHAKELFPDKDIFSWITTPKKAISDLVKASLRNNPRWIIVSETRGSEA
                     YEMLQAVLSGHYVVTTLHAVNARAIPRRFVNMCASGFKINENAVEEDINRYFDFGVHI
                     KKTVVDGKVIRYLNEIVEFSASEPTTVFKQKFINGKFVIENGSLSEDFKEKMAEKFIT
                     FEFPEDQTNTEESLPEEEEVI"
     gene            18914..19729
                     /locus_tag="IXR40_001159"
     CDS             18914..19729
                     /locus_tag="IXR40_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361021.1"
                     /translation="MTKRKGLMDVSELNAYQVAYGKPLDYRDYLNYVGLPCLFMGGFS
                     FALCYYWWIALICGVIGGVYGFKVIMPKSIKRSYELKSLQERNKFINNMTQILTDDSK
                     TVTRALSIAKQRTKGELREDIQILESRLQGADKFQIAEAFREINNKYYSDVVFTQYFE
                     QLETAIYEGRNNSDTMKQIKSYHNDVKRKTEGFMKIKDGYLQDMKQMMFIVAVFIGAI
                     TFAFGFSTFYEGFARSPIGWVFGSIYFLIMVSFMKSFFKHYFDDEIMSLGVSN"
     gene            19729..20526
                     /locus_tag="IXR40_001160"
     CDS             19729..20526
                     /locus_tag="IXR40_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361022.1"
                     /translation="MKVKALKKKRKSSISPLKITKTEHKSFWIKLLGDVYYQKLREMN
                     NSNIAIIKWQKQRLKKSLIFILVGFLMYLFLGKEWYYLAGGIATSVGFYVWQAKSING
                     IYNQFRFERHLQFSKFTRLLIPYLKQKKDGGNLYGVFAKIVKRLDYDTDKKLLMKLMQ
                     EMTDQPNDIRPFTEYAEQTSGTDMSVLFMSTVYDIRQGSADLDVIEELDRLASEELMA
                     GIDSIIDYKSRRFVFFPTKIAMTSFILVVGFAVGVLFMNLKDINFGQ"
     gene            20544..20906
                     /locus_tag="IXR40_001161"
     CDS             20544..20906
                     /locus_tag="IXR40_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4320 family protein"
                     /protein_id="HAQ4361023.1"
                     /translation="MQEQSVMEIIKWFIGLMMIMAMVSIGLFCVQLQDINTFKQQVNY
                     QIERKGGLTTEAVEAIDKYSATNYDRRFTIESDKLNQKVSYGEEIDYTIKATIPIQIL
                     PLPDVTLSFNGNSVSQIR"
     gene            21078..21299
                     /locus_tag="IXR40_001162"
     CDS             21078..21299
                     /locus_tag="IXR40_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361024.1"
                     /translation="MEAIQENRKDNQETSEKNKKKRKKKVDKFTEMTDKIIEKKGLKP
                     KDFDRQAIKEARQKLYDDFVKENISQLLD"
     gene            21318..21593
                     /locus_tag="IXR40_001163"
     CDS             21318..21593
                     /locus_tag="IXR40_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbC/VirB2 family protein"
                     /protein_id="HAQ4361025.1"
                     /translation="MKNLVISKFAMLPRMDFFDNVSKFMSNMTSKLQGISLSVIIFCI
                     VVTGLMFLFGEGPSRTAKKWLTYIVIGAIIIFGASTIGQTIKSVGGF"
     gene            21702..23528
                     /locus_tag="IXR40_001164"
     CDS             21702..23528
                     /locus_tag="IXR40_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361026.1"
                     /translation="MNQRFEYNFEDVEPKLLKKGKGLKKKNKYTLKQAEALVGWIQHN
                     WSDKTTITLICSDTEEGTKYAFDGIEITPFSIGGQEKLLFPDIEGQILQAPDSMISDP
                     NKLILDINDQYKHEPDVAEPTKESKSKLNLKLPSVVLPFAKKKNKLMNELIEPEETDI
                     YEEELEEQEEIEELVVSSEETEEVEEIETVSENEEETEEIFDFEDEEEVENVQKGDLS
                     TSSQNGLEAVNDPQVPPYISSQTPNYSPQYQAPNVLQPLRKHETVQLVTLKEYCDLGE
                     EIETSISQMVEKLKPESLFKFIGIPSTGLTNTRIDEYRSNHAMLRLAEVKFENLREHY
                     SRQIISFKAEALDRLRTAVDIAWKKPYDLDVKKNKAEELSKMEAEAEAKLNEFVKRQE
                     NNVNDKIKKFEIEQEIDLKNFIARQEADKAVFIATEKDRTQNLIDSKAESINADLLET
                     KDKFIDEEMYKMKIEMNKNLFDGKQKIKSELATELAKANDNVWENALKFIQEIQDEIE
                     AKTPIWAAEIKEFNSLEEQEHERMKQTKELQLKEESIEIKRLEAEMNLKRMEELDHEN
                     KMLKIKLETALSKNELLAMEQDTKQVVNGSNRVGALNLFSKR"
     gene            23541..24257
                     /locus_tag="IXR40_001165"
     CDS             23541..24257
                     /locus_tag="IXR40_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361027.1"
                     /translation="MSVFNNKVMLGNCYVNHIGFYDGGTYRVLFLRLSVFSYSKDGKG
                     HYENINAQISCPLDRNGETTTTSSHPKALMNKFIFEKLDRNLVEGMKISIHGNIRGTE
                     QVLLNSGWKNFGQLSPLEKEEYQKIPKNELVTRNQTYIYIEEVSMPEKEEFRKSQSKV
                     TKEDVEVAEPNQADEILSDDTDPVNDEGEVIEVFEAEIIEEEEEIKSFDKRMYREKPK
                     GYVNFEDMYYDEYSNEPPIN"
     gene            24270..27128
                     /locus_tag="IXR40_001166"
     CDS             24270..27128
                     /locus_tag="IXR40_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HAQ4361028.1"
                     /translation="MKLVQNNEVKEIKNGFVKNSNKILGKLKKVGSFKKNKYHTGKIE
                     GEDLPKSLQDKLNVPLVFIGVFLGSIVFLAITYLLNFLKALLVAIGQSESGLLGVEFD
                     PKFSLAYLKPLGDTKQYFMCAVVAVIGVAYLIYGKLNHESEKNLVYGQKGDSRLSTIK
                     EIKRDYHEIPEKTEVYDGIGGVPISHYQDKYYIDRDTVNTVVLGASRSGKGETFVVPL
                     LDNLSRAKIQSNMVVNDPKGELFSASKETLEKRGYRVLVLNIDDPLESMSFNPLQLVI
                     DSWANKDYHEASKRANTLTSMLFASGMSTDNEFFYKSAKSAVNAIILTIVEHCFNNDC
                     IEKITMYNVAQMLNELGSLFYTDPKTGKEKNALDEYFNTLPQGNQAKIQYGSTSFAGD
                     KAKGSILSTASQGIEMFTSDLFGKLTSKMSIDLKEIGFPKSIQFKVNTNLVGKRISIS
                     FLRKENDVIRLIKKYRVKVKALGLCVLNFNEYLQDGDMLDIRYEEEKSRAWYRIEFPK
                     KQANSHDTSLVTKKFKSGKNYSDLEISTLRLKYTDQPTAVFMVIPDYDPSNHVLASIF
                     ISQLYTELASNCKQTPDKKCFRRVHFLLDEFGNMPAIDNMDGIMTVCLGRNMLFDLVI
                     QSYSQLETRYDKAFKTIKENCQNHILIMSNDEETIEEISKKCGHKTTINRSASSKHLD
                     TDSSVTSSAEQERVITVERASQLIEGEQIILRNLHRQDTKRNKIRPFPIFNTKETNMP
                     YRYQFLAEDFDTQRDINEIDIACEHINLSLQDNQIPYARFIKDLKTRLEYSIINNIPI
                     SEEDYQDYLNLSGSQQTINEEELLKLVNTEVKSQDMEGQVLSEQEMKINIYLKESQKE
                     AIELVKVINGRLADENSADMVIKTINSQILDTPFIQSLINDSIAIHNVQESKDQIMIL
                     EQQLANAYELAVFKTKNSILKNKIIKLKNAMTKLAKAI"
     gene            27179..>29584
                     /locus_tag="IXR40_001167"
     CDS             27179..>29584
                     /locus_tag="IXR40_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361029.1"
                     /translation="MQWLKYKWPIIVSLIIILFMAYPQRVFALPWITDNKEVLKFLTK
                     YQDYLQFTKGGFGSIVVQSLSWGLIRGAYFVCKSAENLVPQSLSLFSFVESSSLGAVY
                     QSVLNTVVVGLMILSLMFVGYKMITGKGTVDLKSVGMNVVMSIALILLMPTMISSGIQ
                     FAKTFYKDSTTITKADGGVAWSLIEDGVTDLVYINKNDAYDRLGKDGVQKNALKEKNF
                     FSYDFSEVITVDTAKDLEDDNKKAEYLQSRLTPDGEGNMQAVKIDDGWMSMFSDSFKG
                     GYYRFTKNTFALTLGLLSLAVAYVFSIFIIVTAILELAFKRVLGVLVFATDIETGQRS
                     KVVLSDILQCYLTVGFQGFGLSMFAMFVSYLGTGGGSSVNPFIKAVAYVCAVFVLIKG
                     SGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGSNGFNRAKGSGNGNGSDSGEGED
                     RKPEKNFGETLSKKAGKTGRALGYAHERGLSGLASDGATMASERATKPFKSMRDMAND
                     TKNKFKEGLDDGTVSAINKNSKPMLAKNKEDETGKYADSMPTRLSNRKDGAKVENADR
                     IMSSSERMREAMKNNAESNNNPVSAIQQKVQQDIEERKNAMHGQAKSAEELINQKRQE
                     AKYTPEAMNREEMLRKRVEGRTGTNTDEKEALTKERIQEAKNSNTGLEKLVKENLQNS
                     TSSQGGRSVDVRENIQGSLNGHVGRNVDVRENLQSSSNGQGTKTIGVRENLQSSSTSQ
                     PKTVDVRENVQNSTSSQGFKSVDVRENVQGSSASQPKTVDVRENVQSSTSSQGFKTVD
                     VREN"
BASE COUNT        11233 a         3650 c         5665 g         9036 t
ORIGIN      
        1 tgattttaat agtgtttgat tttattatca tttatagttt gctgttttta ataaagaaag
       61 taactgaata tttaaatcgt taggcatgaa ataaatttta attgaggttg aattatagcg
      121 gtaaatcata caaaatagaa atgtagtctt gttaagcgtc ttgactatct aattttgaat
      181 gaggagggtt gtatatagaa aaagggtagt taaattcgta gatcaaaagg ctacgaagga
      241 gaatatagaa tgacagctat ttataaagca ctaaaaaatt ctaacgtatc agagtacgtt
      301 aagtcgagag tattaaataa taatttagat tacattttag aaaatggtgt tgctgattta
      361 atcagtaaat taagtgatcc tatagatata gatcatttgg tggtatggca agatggtact
      421 ttagaagtat caatatatgg agaattttat agtagaaata aagtaactac attcaaaaat
      481 agtattagtg gtcgagaaga tttaaaagga atcaataaaa atagtaaatt ctatagaaca
      541 aataaagaat tgctagaaaa aatttcaaag cgtgtttttg aattggtgaa tccattttca
      601 aaaacacgta gtaaagaact ttttggaatt ttttatgatg gttttagtgc aaaaagtaat
      661 gtagaaaaat ttttttattt taatgattca gcttatattg cggttaaaga cagtaaaaga
      721 atccctgaag caactttaga atatttagag ccaattaaat tgtctgtttt ttattcactt
      781 tatgagaaag aaatcgctga tgaagcggtt taaggggagt aggatgagta aaaaaatagg
      841 caaagagtcg ttatcgctcg gattgaaaaa agaaattttt aaatttaaaa atatgtatag
      901 tgagccggaa tttagactca tttttcaatt agatatagtg agagggctga aaattagttt
      961 tagttgttta ggttatctgg tttggctatt cattgctaga gtaggatgga gcaatgctta
     1021 tagcttttat aaactgttcg ccggaactga tcgattaaaa gaatcattag aggtgaaaga
     1081 agccttaaat attttaggaa gtcttgcttt cagcctgttt atttttgctt tatttatctt
     1141 acaagtagga aaaataatga tgtcaacaaa tgacaattat attaattatt tgaagccttt
     1201 tcaaaaagga ataaaaatca tttgtagaca gggcacagtt ttatttctac ttagcctgta
     1261 tgagcatgaa attcattttc aaaattatta taatacgaca actaaacttg gtgcattttt
     1321 actcctatat ttagttagta atatagctga aaaaatgctg tttaaacata ttgtaaagca
     1381 agtcttttct gatattaaaa aggaaagcta ttgtttaaaa acaccttatg gaaatttaaa
     1441 aaatgttgag ctgtttttat ttaaaatgga tagtaagtgg gataaatata tctatagaag
     1501 taaagaagta tttttaactg gtagttataa cgaaactctt caggagagcc tgtacgacac
     1561 aggagcaata tttaataatg aacctatggt tttgaaagat ttctttggag attatgaact
     1621 agtttggaat ccaaaacagc ttagtgaaca gggggcagaa aatgaatttg ctgaagttca
     1681 ctaacatagt gtacagaaaa acattatctg aaagaagaac gccttcaaaa gaaagtataa
     1741 gaacgattgg gccgtacaga agactaacga aagatcgtaa aaaaaaggaa agacaatgaa
     1801 aatgtctttc ctttttttga ctacaagtag cctgaaaatg aaattccaaa agactacttg
     1861 tagtcttttg tggcaaaaat aaagagccaa cgaaagctac caacaatcgt tgactcgtaa
     1921 gactgttcgt agtaagaaaa atctttggca atccacgaag tctttatttc ataatttata
     1981 taaatgatta tacagtcatt ttcctgaatt tgcaagtaaa aaagctaaga aatattgttt
     2041 aaacgtttcc ttaaaagaat ctttaaataa atttttttcc aattgaaaac atgactacaa
     2101 gtagactatt tcttttattc tgagttgact acaagtagtc aaaatgatat aatatgtata
     2161 tcaagaaagg agaaacaaaa atgtataacg taggagatca aatagatgag atcgtaaaaa
     2221 taggtaatgt taaacttgat aaaagtaagt actgtatttc agaaaccgaa ataattttta
     2281 atactgaatt agggtatatt ttaatttgga aattgccttt tccaaaagac gaagaaactc
     2341 tgaaaaaaat aaatacttta aaaatcagat attgtgttta tgaagttatt gataaaaata
     2401 cttatgttat aaatcaagta aaagtgatgg ggtaaaaatc tttaaaaaaa ctcttgttaa
     2461 aagtaattct attagcttat aatgttggta ttagttctga agccaaagga acactaaaaa
     2521 attctagtag aaaagttagt tacagactct ctactatgta tgaatgtaac gaaaaaaata
     2581 gcgaaaaaga taattaaata agactaccaa tcttatttaa tggaacttct gtagtaagaa
     2641 aagcgatttg gcaatccacg aagtccacca agatgagcta ccaactcatt ttaattgttg
     2701 cacgtttaaa gtttagcatt taagtgctta ctctaaaggc atagtgtaat tttaggactc
     2761 cttattacgg aatctaaagt taccctatgt cttttttgct attcaaaatt gatagcaagg
     2821 agaaagtgca atgttgaata gttgcgagta tgcggacgtt ttagctaaaa ttcttaaaaa
     2881 tggaattaaa cagtttaata gcaaaaatct agttgctttt aaaaagaata gcaataagat
     2941 tggtgctatt gccggattta cttctaaaac aaacatgata aagactaaag gtcttatata
     3001 tcgttctatt gatcgtgtct tggaagattc agatgtatta acacactgga ctcctaacgt
     3061 gtattcatgg cttggtggcg gtgaaaacaa aacaattttt ggtcacaaag aagctaactt
     3121 aattcagatt aatacttttg tagcagatat tgactatcca gtaggagaaa agaaaacgga
     3181 tttgaattta ctagttcttt atctattgga agaagggtta ttgcctacat tgattgtaga
     3241 tacgccaaaa ggttatcatt gctattttct gattcaaaac tataaccaag aaactgattc
     3301 atttgataag gcaagctata tttctaattc aaatgatttt aaatctttga gagttgctaa
     3361 aagaatatca gaaaatatca gaaaatctat ccaaaatcgt ttaccacaag tcgatatggg
     3421 ctgtaatcat tttggtattt ttagatttcc aactaaaaaa aatattgtac attatgaacc
     3481 taatttcgta gatacgtttg aagggtattt gaaatggtca aaagactttg aagaaaaaga
     3541 atatgcttta aagaggtcta acttgtcatt attagctcct aattctactg gcaagaaagg
     3601 gtctaaacga caaattgata ctaaatggta cgacttttta attcatacgg atattgctga
     3661 aggagataga aataaaactg tttttacctt agccctggca tgtaaatcaa gtggcttatc
     3721 tattggcgag tgtatggatc aattggatca acttcaattc aataatgatt tgtcctattc
     3781 tgaagttgag agaacaataa gaagtgctta tcgtggcgat tacaaaggtg ctaaaagttc
     3841 atatgtcaat gaaattatcg aaaattatgc tacacctacc gagtttgaaa aatactcaat
     3901 aaatgtaaat agacaagctg ttaaacgtaa agggaatcgt gtcgatccgt ctaattgggt
     3961 gaaatttgct aaacctagag aagaacgaaa atatagtcat tttgaagaaa gtaaagctga
     4021 tttattagct tacttagaaa gaaaacaaag atcattgaaa aaaaatgagt tgtttttaag
     4081 tgtctctatg ggaactatat ctgaagaaac acaaattcct gtatctacgt taaaggtgat
     4141 tttaaaagag cttagaacgg cgaatacagt gatattacaa acgtctcgtg gtcggtatgg
     4201 atcgactaaa atagcaacaa gcaaatttgt ggaagctaaa atattaagta cagttattca
     4261 gaataaaaaa gataaacaag tatttgtctt agaattatta ggaacagcaa atagccacgt
     4321 agaaacgatt ttaagacgtt atgaagacaa aacagtaccg ttccatgcga acatactgaa
     4381 agaaagagaa aagagcaaac atgcgccaat tagaggagct aatacaggtt agagttctat
     4441 ttattttttt gatttttaaa tagctaaatt gccaattaac atatctagtg tttctgctca
     4501 ctcctattcc tgttttaacg tatactaatc attagtagtt agtactctct tttacgtatg
     4561 gagtgcatag aactattttt acttgtgtct tttcccttaa tccacgtgta cggaatacag
     4621 cttataactg cgtatgcagt tatgtttgaa ggaggaagat tttctgtggt aattaagaaa
     4681 tatgtttact cacacccgat caatgtattt attatcggta agctaggttt atctgttgag
     4741 gtgttttgtg agttatatgg atttaaacaa ggaactctat cgtcttggat tactagagag
     4801 cgtgaggtag ctgatttgcc tatttctttt ttgtatgctt tgtctctagc ttcaggaggg
     4861 aatatgaatg aggtttatga ttgtttgtgt gagtatgaaa aagagtataa agagtatttg
     4921 aaaatttcag ccccaaaacg gaataaaaaa tatattgaag attagagaaa gaagaaaaga
     4981 ataatttgct ttttgactac aagtagactg atagctactc tgttttttga tagtttgata
     5041 ttggctgttt ttttgttaga attaatatat atcaggtaaa taaaaaaagg gggctattaa
     5101 tgaatattga tgggatttat aatgaatcag attttaaaaa aggcatagta gatattgata
     5161 gaaaagagta tttatttcct gatgaaatag gtttatttaa aattgtaggt gaaactgtct
     5221 gtaggtattg ggggaagaaa ggaaatataa ttttacttgt tgatacgatt gagggaagaa
     5281 agttaaaatt ttcgttttgg agtaatacaa aatattgttg tgaacctgta cctaaaaggg
     5341 aagtagatgt ggctaaagaa agtgtacgat ttttacctga tcgatcaaaa ataactttaa
     5401 tttgtgaacg aacaagtaat gctaaattta caagaattag agatatattg ctttcgacta
     5461 caagtagtca gtcatagagt aagtactttt ggttaaaaat caattgaaga aagtggagga
     5521 agtatatggc agtagttata ttagcagaaa aaccagatca aggagcaaaa tttgcttcag
     5581 cattggccgg aaaaaaatta tcgaaaaaga gtgggaagta tgaatttaaa agtgaaatat
     5641 ttggagatac tattgttact tggggaatag gtcatttggt aggattatca ttacctgaaa
     5701 agtatgagtg gctaccgaat aaagataaat ggcatttaga taatttgcct tttctaccta
     5761 aattcaatga attaaagtat gaagtctcta aaggaaaaaa ccaacaattt tcaatagtga
     5821 agtcatgttt agaaaatgca gatgagataa taattgctac tgatccggat agagaaggag
     5881 aaaatattgc ttataatatt ttcaaattat gcaagcagtc gatttttaat aaaccgataa
     5941 aaagattatg gattaattct ttggttcaaa aagaaattat caaaggattt aaaaatctgc
     6001 gaaattctga agaaacgatc tcttacttca aagaagctaa tgctagacaa attgctgact
     6061 atctagtagg gatgaattat acagagttgt attcattaaa gttgcaagaa aaaggtatat
     6121 cgggtgtggt atcactcggt cgagttcaga caccggtaaa cacacttgtg gttgaaaacg
     6181 atttggcaat tagaaatttt agaccggaaa aatataaaac gattgaatgt catacaaccg
     6241 ataagcaacc aaaagcaata tttaagaata gtcttgaata ctttaaatta gaaaaatttg
     6301 aagaagacac taaaaaattc ggccttgatt ccgccagtac tggaatcata aaaaaaattg
     6361 aggttagtaa aaagcaaaca gaaccacaaa aattgtttag cttgggtggt attcaagaat
     6421 acgctaataa aaaatggaaa tattctgcta aaaaaacaga taaaattatc caaagtctat
     6481 atgatcgtgg atatttatct tatccaagaa ccgatagtga attgataact acaaatgaat
     6541 ttgagtattt aaaagcgaat ttagacgtgt ataagagtgt tttagggatc agtattgata
     6601 caccttgttt agagcctaaa aagcggtttg tagataatga caaagtatta gagcattatg
     6661 cactaatacc aacaatggat attcctgata tagcaaatct gacattagat gaaaaaaata
     6721 tttatgagat cgttactagg cgtgcgtgtc taatgtttgc agaaccttac aagtacgaaa
     6781 atacaaaagt tacattagat gtaaacggct tagaatttac cacaagtggt aatgtaccta
     6841 tatctttagg ttggaagcaa gtagatacta atttagatga atctgatgat aaagaggaaa
     6901 cattacctaa atttcatgaa caagagacaa taaatataga tattagattt attgataaat
     6961 taactaagga acctaaaagg ttgactgaag gtaaattatt aggtaaaacc ggtattatgg
     7021 cgaaattagg gctaggaacg cccgctacac gttctaatat tgtagacact cttctaaata
     7081 gggaatatat taagatagaa aacacgaatg tttatcctac tccaaaggga tatttattat
     7141 gggatttgac aaagaataaa gacctattga ttggaaaacc agaaaataca gcgatatggg
     7201 aagaatcact tgggaaaatt gcgcaaggta gctatacaca ggaagctttt ttaagaaata
     7261 tctataacta tatcaataag actgtttcag atttgaaaaa agtagaattt acttcggatt
     7321 atttagaaaa gactgtaaat caaaataaat ttgatatagg tagttatcaa gtggaagaaa
     7381 agaaaaaagt ttattctatt ttaaatatta ctagtggtga acagttcgtg atatttaaaa
     7441 atatatcagg aaaagcaatc aataaaaaag ttcttcaaga actattacta aataatcgta
     7501 cagataaagt cctttccggc tttaagtcaa aagaaggaaa agcttttaat gcaagattac
     7561 ttttcgatcc aaatgtgatg aaagtggtaa tggagtttga aaagaacagt ccaaaaggcg
     7621 ataaaaagag caaacacgat acagtaaatg gttatgaaat agttgaaaaa gcaaaagtat
     7681 ttgaaataaa agaattagca acaggtgaaa gttttatttt ctataaaaat aatagtggga
     7741 aaactttaag ttcaaaaaca gtcaaagaat tgttagaaaa tgggaaaact aaagagaaag
     7801 taacgggttt tataagtaaa gacaataaaa aatatagtgc ttatcttgtc tttgataata
     7861 aaaacaaagt tataaagaaa gaattttaat tcttagtggc ggaaatcatt tgtttttccg
     7921 cttattttta ttcaaaagtg cccaaaatat aggtatactg aattaaggat aaatacaaaa
     7981 ctagttagag gacagttgaa aaaatacaaa caaattagat tgctattttg ttaaattgga
     8041 agtagaataa taccgttttg atatgtatag tgtgttttac caataaaatt acataaacgt
     8101 gaatatattt ttatgaatta aatgtaaaat gagagcaatt agttttaaaa aagattatag
     8161 gctgttaatc ttagcatata taatccattg gaaaggggga gatccaatga atctaaagaa
     8221 tacaaactca aacaaatcta cactatatgt aatttcagat gattatataa ataagctgaa
     8281 aaaggtggac tatcgtgtcc aaaacaacta tcgagaacaa cgattatatt ttaaatcaaa
     8341 cttgaaaatt tctaacaaaa atgaagaaat aaattattat gtaccattgg cttcagcaaa
     8401 agaaaatcaa cgttctttga ctaataaatc agtgtttaag atttatggtg atcgagaaga
     8461 aaaggacttt ttaggagtac ttcatataaa taatatgatt cctgtgccaa aagattgtgc
     8521 aaaagtatgg acacctaata gcccaaatgt tgatgagaag tataagatgt tagtaatcaa
     8581 acaggcaaaa tatttgaaat tacatgagtc tgaaataaat gaatcatgcg aattacttta
     8641 taattctaag ttaggtaaac ttgatcctag ttactttaag aaaaatcgta aagaagtaat
     8701 tacttatcaa aaaataatga cgaatgtaga atcattggaa gctgttagta tagcagaatc
     8761 ccaaagaaat attcatgtac aaactcaaag tatagatgta gagtaagata ggctaaacct
     8821 atcttatttt attattctat tggatattat gatacattga attttaatcg aatatgtatt
     8881 taaatgttat tatactgtag aagataaaac ttaaaggatg atttctatgg cgagaccgag
     8941 aaaatacaat acagaagaag aaagaaaaga agcaatgaaa aaggctagga aaaaatgggt
     9001 tgaaaaaaat caggaaacta ttgcctatat aagagccaaa tcatttgcta aaaaattcat
     9061 tgaaatgtct gaagatgaag atattgaatt gttggaaaaa tggttagaag atcggaaaaa
     9121 taacggtcaa aatgatgaat aataaccatt gactacaagt agtcaatggt gtagaatggt
     9181 tttagggata gaaatatccc ttttctaaaa gtctaatgac tacaagtagt cgatagaggg
     9241 atcgggaata aaaacagacg attatggcct aaagaaagga ggaatatgaa tattttgagg
     9301 aacgatttat taaatgagcg ttgataaatt tcactaaata ttttcttaat atctatgtat
     9361 tgttcaagcg tagaaaaaaa tattgaaatt attacaaaac cgctcataat ggaaaataac
     9421 gaattatatt aatgaatcgt tcacttttga ccttttttac tagatttttt tgtaggactt
     9481 ttagagaatt tttttgttat ctgattataa ggaggagcta aagttgatag agaatagagt
     9541 actggggttc gtagagtgta aagataattt agacgatact ttagaagtcc ttgaaagtat
     9601 tatatttaac accaaagttc tggatttgaa agcaattaat ggtgatatga caacacatat
     9661 catattagat gaaattagcg caaaagagat tggcgaaact ttaatagcat gggctaataa
     9721 agagctgtaa aagataattt taaaataaag tggccaattg actacaagta gtctgtatag
     9781 tataataaat tatcaaaagt gaggtataca tgatgaaatc aaattttttg ggatatgtaa
     9841 ttgcaatcaa catgtttaaa gggggagttg gtaagtcaac tcttactcag ctaatggctg
     9901 atattctatc ggctagaggc tttaaagttt tagttattga tgttgatcca caaggaacag
     9961 taactaaaaa gtttcaaaga caatatgatt taaaagttgt tgggaaaatg acattgtttg
    10021 aagcagtaat taatatgtct ttcttagact gcatttctcc tgttaaagaa aacttagata
    10081 ttgtgcttgg ttcagaacaa atgtcaaggt ttaccaaagt attaagagat atgtggagaa
    10141 gtactggttt tactgatgaa ggtgaagaag tcttttggaa tttgtttaat tatatgatcg
    10201 gtaatgataa tttaagagat caatatgatt ttattttgtt tgacactatt cctacagttt
    10261 cagaatttac agataacgtt tacgtggcga gtgatttttt agtaattccc acgcaaactg
    10321 agcaagattc tatagacaac ttgcatagta cggttactaa ttatcaaact gctgtaaaag
    10381 aagtaaacgg agatttagaa attttaggta ttgttccata tctagtggat actaaattaa
    10441 aaacaggatt agaactttta tcagaacttc aagaagaata tggagactta gtttattctc
    10501 atattgtttc agaacgaggc gtaattaaac gttggggtag agaaggacta aataaatcta
    10561 tcccacattc taaaactgct tatagcatgt atgtagacat tgtagaagaa acgttagtac
    10621 gtttagaaaa agctacagga gaaaatattt tagaacgtgt ttaggaaagg tgttgcatga
    10681 tgtcgaaaac taaaaaagta actagtgccg gcagtaatgg ttcgggtaat ccgttcggaa
    10741 taaaaagcgg tagtggtgga tttaatatag gacaacaaat gttaaaaggt aaagctggca
    10801 ttaagtctac tggtgataaa cggaaatctg ttagggtacc agttgaatta tacgatgaag
    10861 ttgttaaaga tttatcatac ggggctaaat attcattaat gacagaaatt ttagctttat
    10921 ttttaaaaga atttgaaaca catggaaata gtatagttac tgattttggc aagttgaaaa
    10981 cgagaccagt aaaaatttct gaagaagcct ttaaagtttt gaaagttata aaatttgaaa
    11041 cagatcaatc taatactaat attattgctt cagctttgac atggtatctt gataaaagaa
    11101 aaggaaaagc ataatgaaat gaggtaagac tatggatcat aaatcaaatt attcatacaa
    11161 agaaaattat atttggaagt atgtagtagc cgtttttcta ctggtaggtg gaattattgc
    11221 attggttaaa tgggctataa ttcctaatgc tttagtattt atcaattggt ttgtccctaa
    11281 tttttggagt ttttttggct atatattgat aatctggttt atgtttaaag tactctcttt
    11341 tttctggtcg cctgtatatt ctttgcttgg aaagtggtcg tacctaattt taatagcgac
    11401 agctatttat atcattatgc agattaacta attatgcaga ttttagaaga tattaaaatt
    11461 tattggaaaa ggataatagg ctatacatta gttcttcttg tagtaaattt attcctttcg
    11521 atgatagcgt tggtctttgt taatcaaaga aaagacaatg taactgaatt agtaacgttt
    11581 atttcgtttt tcataagtgg gatttttgct cctttctttg aagaaacctt aatgagagga
    11641 attatccaaa accaattgga attaaaaaca aatttgtcta caagaagcat atatataatt
    11701 gttgcaattt tgtttagtct atcccactta aatttatatt ttattcctta ttttatgacg
    11761 agtttaattt tgtcttttgt ctatgataat tcagataaaa ggctgattgt tccggttact
    11821 attcattgtt tttacaattt aattgtaata ctgttaagtg tagtttttta tacttgaaaa
    11881 aaatagacga aaacctaaaa atacaaggtt tttatctatt ttttttattt tgtttttatc
    11941 tatcaggttg atagaaattg tcataaatga tataattaag tatgaactga tttagtaaaa
    12001 aaattaaagg agtgatagct gttggcaaga tcaagaattg ctaaaattga acagactaaa
    12061 aaggataaaa aaatttctaa aaataaaaca aaattcttta aagctgaaga tgttaagagg
    12121 atagcatggt ctgtgaaaac atttgatgaa gatcgttatg ttaaagtttc aatgaatggt
    12181 ctatttgtac agcttggtaa cttcagtaat tttaaaacga ttgatgaact ttatccggaa
    12241 ataagaaata ttgtggatag taaaggttta atcgtggcta aacggaaatc aagaaactct
    12301 ggtcttgctt actgtaaaaa taaagggatc atgattccgg cttaaatcag tgaaattgtt
    12361 ctttgaaaac ttaatactac tcgtactgta gcaatgttgc tatgttacag ataaaagcgt
    12421 aaggctaata agcaaaatag caaccaagca tactgttatt tcctttgcca agaggtatgt
    12481 aaatacgtta gcaatagaag tgataaggtt agtatttcac gccaaaaaat acaaaagtcg
    12541 atccattgaa actactaatt atgaggtggc gtaaatggta attattcaga atttctatct
    12601 aggaagaacc tatgaaaacc gtcctagaga tcagaatatt gacactaaaa aattcagcac
    12661 agtaataaat gtgctagata cagggtaact ctttactaca agaaatgtag taaagagttg
    12721 ttatgattct ttattacatt tctttctaaa ggaagtgtga taatgaaaaa actaaaactg
    12781 attagcattg ctctattcag cctaatcact atgtcaacgg ctcgccaatc aattgtttcg
    12841 gctgaaggaa cgtctacgaa agcagtagta gaagagtctg gcgataaaaa agttgctata
    12901 gacgacaaag tgaaaaacga agcggaaaaa gcgactgtgg ttcaaggggc agacggcttg
    12961 atgtatgtgg tcgttgatga aaatgatcct gaaaaattgc tagaagctga atctcctttg
    13021 aaaaatcaac aagaaaatac cggcgctgtt gaagtcggtg ttgatgaaaa gagacaagaa
    13081 aaggctgata aagctaacga aaaagtgaaa aactttgacg atattgatta caacgatatt
    13141 agttcgttgc agtcagcgtt gaatgatccg aaattccctt ttttatcgga agatgaatta
    13201 aatgaaaaat tgcaaaagac aaagaataca tttgagtctg aagcgctaat gaaaaagaca
    13261 aggggatatt tcagtcaaag gattttagag ttaagcaata atttaaatga cgtaccgaaa
    13321 agagcgaaag tgagtcggca tgctttagtt agtaaccgtg cttcacaagt aagtgaaaca
    13381 cgaataaacc ctccaaatgg ttatccgtgg gtgatttatt taattaggag caatggttat
    13441 agttatacag aaaattatgc tattagaaga actattgatg ggaaagaagc tttttgttta
    13501 caggccggtg tacaagcgac gaatacatac actggttcaa caagtggtta tctttctaat
    13561 tcgcaaagag aaatgattag ttcgatttta tcagcatata aagaattagg cggttgggct
    13621 aataatgatg ccggaaaaca aagatggata gcaactcaaa tgcttgtttg ggaaaacagt
    13681 aatgaaaagc ctaaaagtat aactgttacg ccaaattgga aaaacggagc tactaagtgg
    13741 aaaaatgatt tagtggctcg tgcaaatgct attagagtaa gaacaaaatg ggattctacg
    13801 tctaagacgg ttgatgaggg agataaagca acctttaaag taactaatac ttatggagat
    13861 cataatttgc atgtgaaatc tgtatctggt ggcggcaaag ctaccataag caatggtact
    13921 ttaactgttg atactacagg agccactgga aacaaaatca ctgtagatat gattaaaggt
    13981 tctcaccctt cagacgcgca ccctacaacg gtatggagta atggttctta tcaaaagctt
    14041 gttaccggtt ctttttacat tagtacttct gttacggtaa atgttaagag aaaaggaact
    14101 gttgaagttt taaaagttga ttcagaaaca aaaaaaccat tatcaggagc aacatttaga
    14161 tttagctact caggtaaaac aaaagatgtt actactgatt cgaatggtaa agcaaaatta
    14221 actgaaaggt tgaaagctgg aactgtagta aaagttaagg agataaaagc tcctaatggc
    14281 taccaactag attcaagcga attttcaatt acagttaaag aaaatcaaaa tgttactacc
    14341 acaagaacca ataagaaatc cacaggttct gtagaaattg aaaagatagg cgatttagat
    14401 ggattaggac taccgaatgt agtattcacg atttataatt ccgataacaa agttgtaaaa
    14461 gataacttaa aaacagatag taatgggaaa ataaaagtcg atgaactgca atttggtaaa
    14521 tattatgcag tagaaaaaca aggtgttact ggttatgatc ccgatggtaa aaaatacaat
    14581 tttgaaataa gtcaagatac tccttttaca aaaccggcta aagtgaaagt aacaaatatt
    14641 tatgaagtat ccataagcga aaaagtatcg gacatgaatg aaagtcaggt attaaaaaat
    14701 aattggtctg ctgatccaaa cgattatctt caatatgaca ttacaactgg aaatctaaaa
    14761 aaatcgggag aaagaaacgt ccaaagtttc attatcgaag ggttttacga caataagaat
    14821 gtagatgtgt caaaaagtga agtatatgtt ggatcaacaa atgtaacaaa ctcttttgac
    14881 attaataacg atactaacaa tggaaaagta attgctaagg cgaagacaag cgtattaacg
    14941 aataatgatt tttataataa gtcctataat ttacggatca ctatgaaaat taaaaaatct
    15001 actcttgaaa acactgaaaa gcaaaaaaat ttaacgattg ttaaaaatag taaagttact
    15061 gtcggttcaa aaatctctaa atctgctagc tctaatgatg tagaaaccgt tttatattca
    15121 agaaaagtta ctatcaatca tattgatgaa aaagacaaac accttttgaa acaagatatt
    15181 gattataaat acgatgggga aacgtatgaa tataaaccta gaaccgattt atttgataaa
    15241 gatggaaaca attataaatc tgatgtaatc cataaaggga aaattgatgg aaaagatata
    15301 gttttaaaca ctccctatca tattccggta ctttctgtga atgtggatcg gattcaaatt
    15361 gatacggcta gagctgttaa aaatggctat ttacctacaa aaatagaact aagtaaaaaa
    15421 gaagaatatg aaaaagaatt agaaaaaatt gtattcaaag ttaaaattac agatatagat
    15481 aacaataaag ttgtttatga tgaaaacttt aaatacaaag aatttaatag tcatatgtcg
    15541 cttgatttac ctacagaata tttaacaaag aataaaaaaa tcaattatag tgttgatatt
    15601 cttttagtgg ataatccaga taaaaacaag ttcgaaactg aaactaaaga tttaagaacg
    15661 atcggttata cttcttctga aaaagtttta acaaacaaag atatgacaaa taaccaagtc
    15721 aactattcag cagtagttag aacagtgaaa gaaagagaga ataataatcc ggtcaaagag
    15781 ttcaatgaga gtatcaatta taaatttact gatagcacta aaacaaaaac aggatatggt
    15841 atatcagttg atttagagcc aacatataga aatgaaattg ggaaacaaat agatatgaaa
    15901 gtctatagtt atccgatgaa tgaattgatt gacagcaaaa ttgacgaaat ctatcaaagt
    15961 gggggaaaag aaacagaagt taagatggat cgcttaaaga atgatggtaa agttgagtcg
    16021 ggtattagta ctcaaaatct ttcattccaa tttccacata tgaatatcga aagaaaaact
    16081 ggaaatatat atgctgacag tcaaagaaat gatgaatcta ttaagtatga attgatcgat
    16141 ggcggtagaa aattatatgt gcctatttgg tgtgatttgg gaaattattc tattgctatc
    16201 aaaagtagta actttggtgg taactatatc tcgttggata tgaaccagaa catagatgtt
    16261 tatgcttata tgtatgcaac gatagatagt gaaacaaaaa aagatgatga attactgctt
    16321 gaacctgttt atccagagtc tactctacca gatggttgga gcaaaaatga gattgattgg
    16381 ctgaataaat aagtttgaaa agtttttatc tatctgatag aattaaataa tgatataggg
    16441 atggtgatag aatgagggtt caaagctatg gtaacagtgt ctttgatgtt aaaagagaat
    16501 ttcaagattc tagaagaaaa accaaaaagc tgatagctta cttcattcta tcagctatcg
    16561 ttttctatat tgtcaagttt gttttggaat taaactcaat agtattcaca gatatggttc
    16621 ataaaatgtt aaatggagaa cctattaatt tcaactttga ttacatgctt gaaaaagcac
    16681 aaagcaatca aattgtggct tttatcgtga gtatctatta ttttattgaa aaatctattt
    16741 tttctttaaa agattttttc tttgaaatgc ttaccaaact aacaacgttt tacaataaaa
    16801 tttcaaaaaa ttaaggagga agtttgaatg ttagatcaaa atacagacag aagttggtgg
    16861 atgattggtg ccgtgatcgt aggtgccatc ttaatcggga cagctaaagt agcttttccc
    16921 gaagtgttta atatcgtcat tacatttttc aaaaacatga tccctacaaa cttaggatag
    16981 ttccactaaa aaattcacgt agtttgatgc gtagaaaaat aataaagaat gaaaaaggct
    17041 acataaagtg atttatgtag cctttttttt ggatggaagt gatgtaatgc taagagatat
    17101 gcccaaaatg attcttttaa tgtttgttgg gttcttttta attttagtga ttgcgtacta
    17161 ttcattaaat ggctatacac aagattcgtc tgtgaaaggt atgcaagaaa cgttaagaac
    17221 tacagcaata gcaaacaggg atgatagtat tcgagtagaa aaaggacgat ttgctttaat
    17281 taagtctgat tttgaaaaag attttaaaga aaaatttggg aaaagtaaaa atctaaataa
    17341 tgaaaccgct gattataaat ttgattatct tacagatggg aaggacggta ttaaagcaat
    17401 taaagtgaag gttgaaagtg gatcaaaaga atatcaagca acttgtattt taaatgttgc
    17461 aaatgattag aggtgtgaaa tttgcgtgtt gtagaggaaa agaagatttc tccaaaaatc
    17521 gaggaaactc ctaaaagtaa aattaatatc gcaagtatta ttaaaaaaaa tggaattaaa
    17581 gaaaactctg aagcgataga aggaaacctt gattttttaa ctaagctttt agaagaagat
    17641 agtggaaatt atgaaccacc aattgaagat gcaaaattaa atatgattcg tgatgattta
    17701 accagaaact attcccaaga agttttacaa gctttaactg atgatgaaat taggcgaaaa
    17761 cttgtacaag ttgttttgaa agaacatggt actttcttta aaaaagataa agaggttgca
    17821 gaatatgtag tacgtgaatg tattggaaca gggattattg agcgaattat gaccaacgat
    17881 gaaattacag atgttggttg gaatggctct caacttagca ttgaaactaa ctctaacaaa
    17941 tggttgtttg acggtgataa attaaatatc acgcaagagt atattgaacg tgttatttct
    18001 aaatatgctg ttgtaaatga tcgggctttt aatagtggta atcctatcat ggatggaatg
    18061 tttaaaaatg ttcgtatatc agctacacac atagataatt caccagatgg ctctacgttt
    18121 tctatgcgtg tggcaaggcc tagattagca ttgaataaag aaaactttga agattttgct
    18181 cctgattata ttttggagct atttgagaaa atgatgaaaa caaaagcaaa tatctgtata
    18241 tcaggggaga caggtacagg taaaacggaa cttcaaaaat tactgctaag ttttattgat
    18301 aatcatgatc gtatgattat gattgaggac gttcaagaaa ctcacgctaa agaattattt
    18361 ccggataaag atattttctc ttggatcact actcccaaaa aagcaatttc agatttagta
    18421 aaagcttctc ttagaaataa tccacgatgg atcattgttt cagaaacacg tggttctgaa
    18481 gcttatgaaa tgcttcaagc ggttttgtca ggtcactatg ttgtaacgac acttcatgcg
    18541 gttaatgcac gtgcgatacc tagacgtttt gtaaatatgt gtgcaagtgg ttttaaaata
    18601 aacgaaaatg cggttgagga agacataaat cgttatttcg attttggtgt ccatatcaaa
    18661 aaaacagtgg ttgatggtaa agtgatccgt tatttgaatg aaattgttga attttctgct
    18721 agtgaaccga ctacagtttt taagcaaaaa tttatcaatg gaaagtttgt cattgaaaat
    18781 ggtagtcttt ccgaagattt taaagaaaaa atggctgaaa aatttattac gtttgaattt
    18841 cctgaagatc aaactaatac agaagaatca cttcctgaag aagaagaggt gatttaagtt
    18901 gaaagtacag gctatgacaa agcgaaaagg tctcatggat gtttcggaac taaacgccta
    18961 tcaagtagcg tatggtaaac cgttagatta tagagattat ttgaactatg ttggattacc
    19021 ttgtttgttt atgggtggct tttcttttgc tttatgttac tactggtgga ttgctttgat
    19081 ttgtggagta attggaggcg tatatggctt taaagttata atgcctaaaa gtattaaacg
    19141 ctcttatgaa ttaaagagtt tacaggaaag aaataaattt attaacaaca tgactcaaat
    19201 tttgaccgat gatagtaaaa cagttactag agcgttatct atagcaaaac agcgaacaaa
    19261 aggtgaatta agagaagata ttcaaatctt agaatcacgt ttacaaggtg ctgataaatt
    19321 tcagattgct gaagcttttc gtgaaatcaa caataaatat tatagtgatg ttgtttttac
    19381 acaatacttt gagcaattgg aaacagctat ttacgaaggt agaaataatt cagatactat
    19441 gaagcaaata aagagctatc ataatgatgt gaaacgtaaa acagaaggtt ttatgaaaat
    19501 caaagacggc tatcttcaag atatgaagca aatgatgttt attgtagctg tttttattgg
    19561 agctataact tttgcttttg gtttttctac tttctatgaa ggttttgctc gatcacctat
    19621 cggatgggta tttggatcta tttacttttt gattatggtt agcttcatga agtcattttt
    19681 caaacattat tttgatgatg aaataatgag tttgggggta agtaattaat gaaagttaag
    19741 gctttaaaaa agaaaagaaa atcaagtatt agccccttga aaattacgaa aacagaacat
    19801 aaaagctttt ggattaaatt actaggtgat gtttattatc aaaaattacg tgaaatgaac
    19861 aattccaata ttgcgattat taagtggcaa aaacaacggt taaaaaagtc attgattttt
    19921 atcctagtcg gattcttaat gtatctattt ttagggaaag aatggtatta cttagccggt
    19981 ggaattgcta cttcagtagg tttttatgtt tggcaagcaa aatcaatcaa tggtatctat
    20041 aatcaatttc ggtttgaacg acacttgcaa tttagtaaat ttacacggct attgatcccc
    20101 tatctgaaac aaaaaaaaga tggcggaaat ttatatggtg tttttgcaaa aatcgtaaaa
    20161 agactagatt atgataccga taaaaagcta ttaatgaagc ttatgcaaga aatgacagat
    20221 cagcctaacg atattagacc ttttacggaa tatgcagaac agacttctgg aacagacatg
    20281 tccgtattat ttatgtctac agtttatgat attcgacaag gttcggcaga tttggatgtt
    20341 attgaagagt tggatcgttt agcttctgaa gagttaatgg ccggaatcga ttcaatcatt
    20401 gactataagt cgaggcgttt tgtcttcttt cctacaaaaa ttgcaatgac ttcatttatt
    20461 ttagttgtcg gttttgcagt aggcgttctt ttcatgaacc taaaagatat taactttggg
    20521 caataaagga aaggagaaag tcaatgcaag aacaatccgt tatggaaatc attaaatggt
    20581 ttataggttt aatgatgatt atggcaatgg tttctatagg acttttttgt gttcaattac
    20641 aagatattaa tactttcaag caacaagtaa attatcaaat tgaacgaaaa ggaggtctga
    20701 cgacagaagc tgttgaagca atcgacaaat attcggctac taattatgat agacgtttta
    20761 caattgaaag cgataagtta aatcagaaag tatcttatgg agaagaaatt gattatacga
    20821 tcaaagcaac tattccaatt caaattttac cgcttcctga tgtaacttta tcgtttaacg
    20881 gaaatagtgt ttctcaaata agatgagagg aaggataaaa tgcaagagaa taatgtttcc
    20941 agaataattt atttgattgg cggattgata attttatcct tagctattgc cggtcttgta
    21001 gagcattggc cggaaataaa gttattaata agaaactttt acgacaataa aatgattaaa
    21061 atgtaggagg tatagatttg gaagcaattc aagaaaatcg taaggataat caagaaacaa
    21121 gtgaaaaaaa caaaaaaaaa agaaaaaaga aagtagataa atttacggaa atgaccgata
    21181 aaatcattga aaagaaagga cttaaaccta aagactttga ccgtcaagca atcaaagaag
    21241 cacgacaaaa actgtatgat gattttgtta aagaaaacat atcacagctt ttagactaac
    21301 atttaggggg aaataaaatg aaaaatttag ttatcagcaa gtttgcaatg ttaccaagaa
    21361 tggatttttt cgataatgta agtaagttta tgtcaaatat gacttcaaaa ctacaaggaa
    21421 tttcactatc tgtaattatc ttttgtattg tggttactgg tttgatgttt cttttcggag
    21481 aagggccaag tcgtactgct aaaaaatggt taacttatat cgtgattggg gcaataatta
    21541 tcttcggagc ttcaactatc ggacaaacga tcaagtccgt tggtggtttc taaggggaag
    21601 cttcttagaa ctaaaaaatt cgcaagtatt gcatgaaaga gcattgagtg attaatgctc
    21661 ttttttattt tgaaaaacta taaactaagg agatttaaac tatgaaccaa cgattcgaat
    21721 ataattttga agatgtagaa cctaagttac tgaaaaaagg aaaaggatta aaaaagaaaa
    21781 ataaatatac tctcaaacaa gcagaagcat tagtaggatg gattcaacac aattggtcag
    21841 acaagacaac aattaccttg atctgttcag acacagaaga aggaacaaag tatgcttttg
    21901 atggaattga aattactcca ttttcgattg gcggacaaga aaaattattg tttcctgata
    21961 ttgaaggaca aattttacaa gcgccggaca gcatgatttc cgatcctaat aaactgattt
    22021 tggatattaa cgatcaatac aaacacgaac cagacgtagc agaaccaaca aaagaatcaa
    22081 agtcaaaatt aaatttgaag ctcccttcag tagtattacc atttgctaag aagaaaaata
    22141 aacttatgaa cgaattgatt gaaccagaag aaacggatat ttatgaagaa gaattagaag
    22201 aacaagaaga gatcgaagaa ttagttgtgt cttctgaaga aacagaagaa gtagaagaaa
    22261 ttgaaactgt ttctgaaaat gaagaagaaa cagaagaaat ctttgacttt gaagatgaag
    22321 aagaagtgga aaatgtacag aaaggcgatc tatctacaag tagtcaaaat gggttggaag
    22381 ctgtaaatga tccacaagtt ccaccatata tatcttcaca aactcccaat tactctccac
    22441 agtatcaagc gcctaatgtc ttacaaccat taagaaaaca cgaaacagtg cagttagtta
    22501 cgcttaaaga gtactgtgat ttgggagaag aaattgaaac ttcaatttct caaatggtcg
    22561 aaaagttgaa accagaatct ttattcaaat tcatagggat tccttctaca ggtcttacaa
    22621 atactcgtat tgatgaatat agaagtaacc atgctatgtt gcgattagct gaagtaaaat
    22681 ttgaaaattt aagagagcat tattcacggc aaattatttc ttttaaagca gaagccctag
    22741 atcgtttaag aactgcggta gatattgctt ggaagaagcc ttacgattta gatgtgaaga
    22801 aaaacaaggc cgaagagtta tcaaaaatgg aagcagaagc agaagctaaa ttaaatgagt
    22861 tcgtgaaacg tcaggaaaac aatgtaaatg ataaaatcaa aaagtttgag atcgaacaag
    22921 aaatagattt aaaaaacttt attgcaagac aagaggcaga taaagcggta tttattgcta
    22981 cagagaaaga tcggactcaa aatttaattg attctaaagc ggaatcaatc aatgcagatt
    23041 tacttgaaac aaaagataaa tttattgatg aagaaatgta caaaatgaaa attgaaatga
    23101 acaaaaattt atttgatggc aagcaaaaaa ttaaatcaga attggctact gaactcgcta
    23161 aggcaaatga taatgtttgg gaaaatgcgc tgaaatttat tcaagaaatt caagatgaaa
    23221 ttgaagctaa aacaccaatt tgggctgctg aaatcaagga gtttaatagt ttagaagaac
    23281 aagaacatga acgtatgaag caaactaaag aacttcaatt aaaagaggaa agtattgaaa
    23341 tcaagcgttt ggaagctgaa atgaatttga agcgtatgga agaattagat catgaaaata
    23401 aaatgcttaa aattaaactt gaaactgccc tttcaaaaaa tgagttatta gctatggaac
    23461 aagatacaaa gcaagtggtg aatggatcaa acagagttgg tgcacttaat ttatttagta
    23521 aacgttaaag gagaacggat atgagtgttt ttaataataa agttatgtta gggaactgtt
    23581 atgtgaacca cattggtttt tacgatggag gaacatacag agttttattc ttacgtttat
    23641 ctgtttttag ttactcaaaa gatggaaagg ggcattatga aaatattaat gcacaaattt
    23701 cttgtccttt agatagaaat ggggaaacca cgactacaag tagtcaccct aaagccttga
    23761 tgaataaatt tatctttgaa aagttggatc gcaatttggt tgaggggatg aagataagta
    23821 ttcatggaaa tattcgtgga acagaacaag tgcttcttaa cagtggttgg aaaaactttg
    23881 gtcaattatc gcctttagaa aaagaagaat atcaaaaaat tcctaaaaat gaattagtaa
    23941 caagaaatca aacatatatc tatatagaag aggtaagtat gccagaaaaa gaagaattta
    24001 gaaagtctca atctaaggta acaaaagaag atgtggaagt tgcagaaccg aatcaagcag
    24061 atgaaatttt atccgatgat actgatccag tgaatgatga aggagaggtt attgaagttt
    24121 ttgaagctga aattatcgaa gaggaagaag aaattaaaag ttttgataaa agaatgtatc
    24181 gagagaaacc aaaaggttat gtgaattttg aagatatgta ttatgacgaa tattctaatg
    24241 aaccaccgat caattagtgg gggtcaaata tgaagctagt acaaaacaat gaagtgaaag
    24301 aaataaaaaa cggctttgtt aaaaactcga acaaaatttt gggaaagctg aaaaaagtag
    24361 gtagtttcaa aaaaaataaa tatcatactg gaaaaattga gggagaagat ttaccaaaaa
    24421 gtttacaaga taaattgaat gttccgcttg tatttatagg tgttttttta ggttcaatag
    24481 tttttctagc aataacgtac ttattgaact ttttaaaagc tttgttagtt gcaatcggac
    24541 agtcagaaag tgggctactt ggtgtagagt tcgatcctaa gtttagtttg gcatatctaa
    24601 aaccacttgg ggatacgaaa caatacttta tgtgtgctgt ggttgcggta ataggagtcg
    24661 cttatttaat atatgggaaa ttaaatcatg aaagtgagaa aaatcttgtt tacggtcaaa
    24721 aaggagattc aagactttca actatcaaag aaattaagag agattaccat gagataccag
    24781 aaaaaacaga agtgtatgat ggtattggtg gtgtgccaat tagtcactat caagataaat
    24841 attatattga tagagacaca gtaaataccg ttgttttggg agcttcacga tccggtaaag
    24901 gggaaacatt tgttgttcct ttattagata atcttagccg agcaaaaata caaagtaata
    24961 tggtcgtgaa tgatccgaaa ggagaattgt ttagcgcttc aaaggaaaca cttgaaaaac
    25021 gaggttatcg tgtattagtg ctaaatattg atgatccact tgaatcaatg agttttaatc
    25081 ctttacaact agtaattgat agttgggcta acaaggacta tcacgaagct agtaagcgag
    25141 cgaatacttt aacttcaatg ctctttgctt caggaatgag tacagataat gagtttttct
    25201 ataaatcagc taaatcagcg gtcaatgcga ttattttaac gattgtagaa cactgtttta
    25261 acaatgattg cattgaaaaa attacaatgt acaacgtggc tcaaatgctg aacgaattag
    25321 gaagcttatt ttacactgat ccaaagactg gaaaagaaaa aaatgcttta gatgaatatt
    25381 tcaatacttt accacaaggg aatcaggcca agattcagta tggttctact tcatttgccg
    25441 gtgataaagc caaaggttcg attttatcta ctgcttcaca aggtattgaa atgtttacaa
    25501 gtgatttgtt cgggaagtta acaagtaaaa tgtctattga tttgaaagag ataggctttc
    25561 ctaagtccat acaatttaaa gtcaatacga atttagttgg aaagaggatt agtatttcat
    25621 ttttgagaaa agaaaatgat gtaattagat taattaagaa gtatcgagtg aaagtaaaag
    25681 ctttagggct atgtgtttta aattttaatg aatatcttca ggatggagat atgttggata
    25741 tacgatatga agaagagaaa tcgagagcat ggtatcgtat tgaatttccc aaaaaacaag
    25801 caaatagtca tgatacttct ttagtcacta aaaaattcaa gtcaggtaaa aattattctg
    25861 acttagaaat cagcacctta cgattaaaat acacggatca gccaactgct gtgttcatgg
    25921 ttattccaga ttatgatccg tcaaatcacg tacttgcaag tatttttatc agtcaacttt
    25981 atacagaatt agcaagtaat tgtaagcaaa caccggataa aaaatgtttt aggcgagttc
    26041 atttcttgtt agatgaattt gggaatatgc cggctataga caatatggat gggattatga
    26101 cggtatgtct aggaagaaat atgctttttg acttagtgat tcaatcctat agtcagctag
    26161 aaacaagata tgataaagct tttaaaacaa ttaaagaaaa ttgtcagaat catattttaa
    26221 tcatgtcgaa cgatgaggaa acgatagaag agatttcaaa aaaatgtggt cataagacaa
    26281 caataaatag aagtgctagt tctaaacatt tagatactga tagctcggtc actagttcgg
    26341 cagagcaaga gcgagtaatt acagttgagc gtgctagtca attgattgaa ggggaacaaa
    26401 ttattttaag aaaccttcat agacaagata caaaaagaaa taagattaga ccatttccta
    26461 tttttaatac taaagaaaca aatatgccgt atagatacca atttttagca gaagactttg
    26521 atactcaaag agatattaat gagattgata ttgcatgtga acatatcaat ctatctttac
    26581 aagataacca aattccatat gcaaggttta tcaaagattt aaaaacacgt ttggagtatt
    26641 caattattaa taatattcct attagtgaag aagactatca ggattatcta aatttatcag
    26701 gatcacaaca aacaattaat gaagaagagc tgttaaaact ggtaaatacg gaagtaaaaa
    26761 gtcaagatat ggaaggtcaa gttttatcag aacaagaaat gaaaattaat atttatctaa
    26821 aggaaagtca aaaggaagca atagaattag taaaagtaat taatggaagg ttagctgatg
    26881 aaaattcagc agatatggtt ataaaaacca ttaattcaca aatccttgat acgcctttca
    26941 ttcaatcttt aatcaatgat tctatagcta ttcataatgt tcaagagagt aaggatcaaa
    27001 ttatgatcct agaacaacaa ttagctaatg cttatgagtt agcagtgttt aaaacgaaaa
    27061 attcaatact gaaaaataaa attatcaagt tgaaaaatgc tatgactaag ctagcaaaag
    27121 caatttagag agaagggaag aaatattgac tgaatctatt aattggagaa aactaaatgt
    27181 gcaatggtta aagtataaat ggccaatcat agtttcccta ataatcattc tatttatggc
    27241 ctatccgcaa cgagtttttg cgttgccgtg gattacagac aataaagagg tattaaaatt
    27301 tttaacaaaa tatcaagatt atcttcagtt tactaaaggt ggttttggaa gcattgtcgt
    27361 tcaaagttta tcgtgggggc tgattagagg tgcatatttt gtttgtaaat cagcagaaaa
    27421 ccttgttcca caatcgctaa gtttgtttag ctttgttgaa agcagtagtt taggtgctgt
    27481 ttatcaatct gtattaaaca cggtggttgt aggattaatg atcctttcat tgatgtttgt
    27541 tggttacaag atgattactg gaaaaggaac agtggattta aaatcggttg gaatgaacgt
    27601 agtgatgtct atagcattaa tacttttaat gccaaccatg atttctagtg gtattcaatt
    27661 tgctaaaaca ttttataagg actctactac gattacaaaa gctgatgggg gcgttgcttg
    27721 gtcattgatt gaggacggtg taactgattt agtatatatc aataaaaacg atgcttatga
    27781 tcggttgggt aaagatggcg tacaaaaaaa tgcgttaaaa gaaaagaatt tcttttccta
    27841 cgatttcagt gaagtaatca cagttgatac agctaaagat ttagaagatg ataataaaaa
    27901 agctgaatat cttcaatcta ggttgacacc agatggcgaa ggaaatatgc aagccgttaa
    27961 gattgatgat ggttggatgt cgatgttctc tgatagtttc aaaggagggt actacaggtt
    28021 tactaaaaat acttttgcat tgactttagg attactttcg ttagctgtag cctatgtttt
    28081 tagtattttt atcatagtca ccgctatttt agaactggca tttaagcgtg tgttaggggt
    28141 tcttgttttt gcaacagata ttgagacagg acagcgttca aaagttgttc tatcagatat
    28201 tctacagtgc tatttgactg taggctttca aggatttgga ttatccatgt ttgcaatgtt
    28261 tgtttcctat ttaggaacag gcggagggtc ttccgttaat ccgtttatta aggctgtagc
    28321 ttatgtatgt gccgtttttg ttttaatcaa aggcagtgga acagtcatga gatactttgg
    28381 tgttgatatt ggactcaaag aaggctatgg gcaacttgct tctgcttttg gaatgggtgc
    28441 aatgctgttt agaaaaggat caaatggatt taatcgtgcc aaaggaagcg gaaacggaaa
    28501 tggatcagac agcggagaag gagaagatcg aaaaccagaa aagaatttcg gtgaaactct
    28561 atcaaaaaaa gctggcaaaa ctggaagagc tttgggatat gcccatgaac gtggattatc
    28621 aggtttagct tcagatggag ctacaatggc tagtgaaaga gcaacaaaac catttaagag
    28681 tatgcgtgat atggctaatg atactaagaa taagttcaaa gaaggtttag atgatggtac
    28741 agtgtccgct attaataaaa atagcaaacc tatgttagct aaaaataaag aagatgaaac
    28801 tggaaaatac gctgattcca tgccaacacg tctttcgaat agaaaagatg gtgctaaggt
    28861 tgaaaatgcc gatagaatta tgtctagttc tgaacgtatg cgtgaagcaa tgaaaaataa
    28921 tgctgaatcg aataataatc ctgtaagtgc aattcagcaa aaagttcaac aagatattga
    28981 agaacgtaaa aatgctatgc acggtcaagc taagtctgct gaagaattaa ttaatcagaa
    29041 gcgacaagaa gctaaataca cgcctgaagc aatgaatcgt gaggaaatgt taaggaaacg
    29101 tgtagaaggg cgtacaggaa ctaatacgga cgaaaaagaa gcgttgacca aagaaagaat
    29161 ccaagaagct aaaaactcaa ataccggatt agaaaaattg gtcaaagaaa atctacaaaa
    29221 ttctacaagt agtcaaggtg gtcgatcagt agatgtccga gaaaatattc aaggttcatt
    29281 gaatggtcat gtcggacgga atgttgatgt aagagagaat ttacaaagtt cttcaaatgg
    29341 tcaaggtact aagacaattg gtgttcgaga aaatctgcaa agtagcagta caagtcaacc
    29401 aaaaacagta gatgttcgag aaaatgtaca aaattctaca agtagtcaag ggtttaaatc
    29461 agtggatgtt cgagagaatg tgcaaggtag cagtgcaagt caaccaaaaa cagtagatgt
    29521 ccgagaaaat gtacaaagtt ctacaagtag tcaaggattc aaaacagtag atgttcggga
    29581 gaac
//
LOCUS       DACGEU010000028        29099 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.028, whole genome shotgun sequence.
ACCESSION   DACGEU010000028 DACGEU010000000
VERSION     DACGEU010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29099)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29099)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29099
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.028"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..1031)
                     /locus_tag="IXR40_001168"
     CDS             complement(<1..1031)
                     /locus_tag="IXR40_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAQ4361030.1"
                     /translation="MKSNEKTPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMVALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTV"
     gene            complement(1113..1802)
                     /locus_tag="IXR40_001169"
     CDS             complement(1113..1802)
                     /locus_tag="IXR40_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HAQ4361031.1"
                     /translation="MKKKIIRLMLISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(1908..2276)
                     /gene="rplL"
                     /locus_tag="IXR40_001170"
     CDS             complement(1908..2276)
                     /gene="rplL"
                     /locus_tag="IXR40_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HAQ4361032.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(2329..2832)
                     /locus_tag="IXR40_001171"
     CDS             complement(2329..2832)
                     /locus_tag="IXR40_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HAQ4361033.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     gene            complement(3242..3931)
                     /gene="rplA"
                     /locus_tag="IXR40_001172"
     CDS             complement(3242..3931)
                     /gene="rplA"
                     /locus_tag="IXR40_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HAQ4361034.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(4035..4457)
                     /gene="rplK"
                     /locus_tag="IXR40_001173"
     CDS             complement(4035..4457)
                     /gene="rplK"
                     /locus_tag="IXR40_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HAQ4361035.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            4800..5468
                     /gene="sdaAB"
                     /locus_tag="IXR40_001174"
     CDS             4800..5468
                     /gene="sdaAB"
                     /locus_tag="IXR40_001174"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit beta"
                     /protein_id="HAQ4361036.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            5481..6353
                     /gene="sdaAA"
                     /locus_tag="IXR40_001175"
     CDS             5481..6353
                     /gene="sdaAA"
                     /locus_tag="IXR40_001175"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HAQ4361037.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(6444..7463)
                     /locus_tag="IXR40_001176"
     CDS             complement(6444..7463)
                     /locus_tag="IXR40_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HAQ4361038.1"
                     /translation="MEAGAFGYIRGGSEDEWTMKENTTSFNTKKIMPRILRGIDSADL
                     HTSVFGIELDTPIIQAPSAAQGLAHEKGEADTAKGVAAAGSIFSISTYANTTIKDAAD
                     AAPGAPQFFQLYMSKDDRFNEFILNKAVEAGAKAIILTADSTLGGYREEDVINQFQFP
                     LPMPNLAAYSEQSASGNGEGKGIAEIYAAAKQGLTPDDIKTIKEITHLPVIVKGIQSP
                     EDAVIAISAGADGIWVSNHGGRQLDGGPASFEVLPKIAEVVNKRVPVIFDSGVRRGEH
                     VFKALASGADLVAIGRPVIYGLNLGGAEGVTSVFEHLNKELSITMQLAGTKTIDEVKN
                     TKLMD"
     gene            complement(7636..8523)
                     /locus_tag="IXR40_001177"
     CDS             complement(7636..8523)
                     /locus_tag="IXR40_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAQ4361039.1"
                     /translation="MTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEVSDKEKT
                     AESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDGQIQATG
                     DLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSMGGVSAL
                     RYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQDYQQMI
                     GNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTGENASHS
                     MLHENQEVDQLVSRFIWKE"
     gene            complement(8600..9145)
                     /gene="nusG"
                     /locus_tag="IXR40_001178"
     CDS             complement(8600..9145)
                     /gene="nusG"
                     /locus_tag="IXR40_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HAQ4361040.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(9246..9416)
                     /gene="secE"
                     /locus_tag="IXR40_001179"
     CDS             complement(9246..9416)
                     /gene="secE"
                     /locus_tag="IXR40_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HAQ4361041.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(9440..9592)
                     /gene="rpmG"
                     /locus_tag="IXR40_001180"
     CDS             complement(9440..9592)
                     /gene="rpmG"
                     /locus_tag="IXR40_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HAQ4361042.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            9754..10398
                     /locus_tag="IXR40_001181"
     CDS             9754..10398
                     /locus_tag="IXR40_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAQ4361043.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(10454..10957)
                     /locus_tag="IXR40_001182"
     CDS             complement(10454..10957)
                     /locus_tag="IXR40_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HAQ4361044.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(10970..11016)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            11554..12519
                     /locus_tag="IXR40_001183"
     CDS             11554..12519
                     /locus_tag="IXR40_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HAQ4361045.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGNDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(12618..13790)
                     /locus_tag="IXR40_001184"
     CDS             complement(12618..13790)
                     /locus_tag="IXR40_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4361046.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMATIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(13777..14922)
                     /locus_tag="IXR40_001185"
     CDS             complement(13777..14922)
                     /locus_tag="IXR40_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4361047.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(14936..15868)
                     /locus_tag="IXR40_001186"
     CDS             complement(14936..15868)
                     /locus_tag="IXR40_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4361048.1"
                     /translation="MIIEIDKLVKRYGDFVALNHFDLQVQEGEVLGLLGPNGSGKSTA
                     INCMLSLLNYDKGTIKLFGTTMTPENYAVKAMIGVVPQDVAVFDELSVQENIDYFCGL
                     YVSEKEKRKALIEEVIQLVGLEKYVSFRPGELSGGLKRRLNIACGIAHKPRLIFLDEP
                     TVAVDPQSRNKILESIKELNRQGATIVYTTHYMEEVEILCDQIVIMDQGQVIAKGTKE
                     SLKDMVRTADRLTIDIPLLPENVLSAIQRTIASDGIAYKKGQLQVTTTELNTVLLPIL
                     TILQEEKISYGKIATKEASLNDVFLEITGKDLRD"
     gene            15985..17064
                     /locus_tag="IXR40_001187"
     CDS             15985..17064
                     /locus_tag="IXR40_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAQ4361049.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            17061..17679
                     /locus_tag="IXR40_001188"
                     /pseudo
     CDS             17061..17679
                     /locus_tag="IXR40_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325326.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
     gene            complement(17789..18016)
                     /locus_tag="IXR40_001189"
     CDS             complement(17789..18016)
                     /locus_tag="IXR40_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005229738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAQ4361050.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(18119..20707)
                     /locus_tag="IXR40_001190"
     CDS             complement(18119..20707)
                     /locus_tag="IXR40_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HAQ4361051.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(20727..21386)
                     /locus_tag="IXR40_001191"
     CDS             complement(20727..21386)
                     /locus_tag="IXR40_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAQ4361052.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVARHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(21435..21938)
                     /gene="trmL"
                     /locus_tag="IXR40_001192"
     CDS             complement(21435..21938)
                     /gene="trmL"
                     /locus_tag="IXR40_001192"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HAQ4361053.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(22159..23025)
                     /locus_tag="IXR40_001193"
     CDS             complement(22159..23025)
                     /locus_tag="IXR40_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HAQ4361054.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            23134..23775
                     /locus_tag="IXR40_001194"
     CDS             23134..23775
                     /locus_tag="IXR40_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HAQ4361055.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(23837..25198)
                     /gene="mgtE"
                     /locus_tag="IXR40_001195"
     CDS             complement(23837..25198)
                     /gene="mgtE"
                     /locus_tag="IXR40_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HAQ4361056.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(25216..26115)
                     /locus_tag="IXR40_001196"
     CDS             complement(25216..26115)
                     /locus_tag="IXR40_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HAQ4361057.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(26117..26914)
                     /locus_tag="IXR40_001197"
     CDS             complement(26117..26914)
                     /locus_tag="IXR40_001197"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HAQ4361058.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(26892..27596)
                     /locus_tag="IXR40_001198"
     CDS             complement(26892..27596)
                     /locus_tag="IXR40_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HAQ4361059.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            27727..28302
                     /locus_tag="IXR40_001199"
     CDS             27727..28302
                     /locus_tag="IXR40_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HAQ4361060.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            28420..29097
                     /locus_tag="IXR40_001200"
     CDS             28420..29097
                     /locus_tag="IXR40_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HAQ4361061.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
BASE COUNT         8563 a         6167 c         5231 g         9138 t
ORIGIN      
        1 aatacagtat tatttcggtt gcttgctgct tcacctagcc cttgtactcg tgtttgattg
       61 gcgacttgac caaattgatt cccgacgtct aataaaataa tagctaaaag caaaatggcc
      121 aaatggcttc cgccaaccaa taaagcaata aagcttattg tttgcataac aagtcccata
      181 tacacgattt ttctttcaga ataagaatct gccagtcgtc ccacgatagg tgcagcaact
      241 gctccagaca aaccaaaaat cgctaatatc cctgcttcga atgttcccca attgtaggcg
      301 ggactgctga tataaaaaat caacgtagac caaaagatcg aaaatgttcc aaacatgaaa
      361 aatccactga ctgccgcttc tcttaataga cgttgagaag caactaaatg cggcaaactt
      421 ttaagtgaat caaggtatga aacagctgta ctactttgct ggacagaacg cggcattttc
      481 cagtaaagca gaagtgtaag aattccgact gcacataaag caaataaata gatcatccgc
      541 caagaaaaaa gactggcaac aataccagat accgtccgag aaagcaaaat ccccacgagt
      601 aaaccgctaa gcaatgtacc catgaccttc cctcttgctt ttggtcccgc tagtaccgca
      661 ccgtaaggaa tgatgatttg cggcacgatc gaaagtaatc ctattaaaaa agaagcgcat
      721 gcaaataacg taaacgaagg cgcaaaaaaa gcggccaaca gagagacggc agataacgct
      781 accattcgaa tgatcaattt tggacgatcc accacgtccc ctaaaggaac taaaaacagt
      841 aaccctaacg catagcctaa ttgggtcaac atcgtcaata tcccgactgc acttgtgcta
      901 acagataaac tagctgctac ttttgttcca atcggctgga tgtaatacat attggcaaca
      961 acaacgccac aagtgattga taatagtaaa ataagcgaag ttgttaaagg tgttttttca
     1021 ttactcttca ttgatttccc ccatttccta tcttagttta caacttatgg aaaagattgg
     1081 aaatagaaaa atacaactat tcgccacact tattatttgt gcttttgttt tccttgtttt
     1141 ttcttgcgat ctttataaat gaagacaact aaccctacta gcacagtaac acttgcaacc
     1201 aacgtgactg cagttttgtt atatccgtga aacagagctt ctccaccaca cgcatacaac
     1261 acagacgaag ggatgactcc aatcacgatc gacaatatga tttgctgtag aggcaatttc
     1321 atcgcatctg cagcaaaatt gaccatagaa gatggaataa ccggtatcat atagcctaac
     1381 attacaccta tttttggatg tttcatttgt cggattgctt gcacccaatg attcgtttcg
     1441 gttttcttat ctaaaaattt taagcgatgc ataaggaaaa ttgcagtgat gttaccaaga
     1501 gcattaccca aaatgttgat gatcgcacct gtcagtggtc caaagctcaa accagcaatg
     1561 actccaacta ctgaagtagg aatacctgga acagcacaca tcaccgctgt caatacgatc
     1621 aagagtatcg atgcaaaagt cccatgcgaa cgaatatgtg cgagtagctc tgccttactc
     1681 gctctcggat ttaaaaataa ttggatgtct gtctgatatt ctaaatacaa ccgatagccc
     1741 actaccagta tcagaatgat tcccaacgag atcaacatca atcggattat tttctttttc
     1801 atatttcctc ctgaaaaaaa tctatattca ttaaataata gtttaacata aaaacaaaaa
     1861 agcaccgaaa tccaacatag gatctcagtg cttttaaata gtaaaaatta tttaacagtt
     1921 acagatgcgc caacttcttc aagtttagct ttcaattctt cagcttcttc tttagatacg
     1981 ccttctttaa ctggtgcagg agcgccatca actacagctt tagcttcttt caagcctaaa
     2041 ccagttgctt cacgaactgc tttgataact ttaacttttt ggtctccagc tgcagttaat
     2101 tctacagtga attctgtttg ttcttcagca gcagcagcgc caccagcagc agctacagct
     2161 acaggagcag cagcagatac gccaaattct tcttcaatag ctttaactag gtcgttaagt
     2221 tctaggatag ttgcttcttt taactcagca acgatgtttt caatgttcaa tgccattata
     2281 atttcctccg tttaattgtt cttttttatt taatgcttta tgcggcaatt aagctgcatc
     2341 tccatcttct ttgtctgcca ctgctttgac agcgtaagcc acgttgcgga ctggcgcttg
     2401 tagtacagat agcaacatag atagaagtcc ttcgcgattt ggcaattttg ccaatgctgt
     2461 gatttcttcc aatgaagaga ctttaccttc gatgataccg cctttgattt ctaatgcttt
     2521 tgcttcttta gcaaattcgt ccatgatttt cgctggtgcg actacatctt cgttactgaa
     2581 tgcaacagct gtaggtccag tgaatacttc gtccatgcct tcaaggccag cttttttagc
     2641 tgcacgtgaa agaatagaat ttttgataac tttcatttct acgttagcat cacgaagttg
     2701 tttacgtaaa cgtgttactt catcaactgt taatccgcgg tagtcaacga ctactactga
     2761 tgcagctgct gtaaattttt cgcttacttc atcaacgatt gctgcttttt ttgcgataat
     2821 tgcttcactc atttttgagt ttcacctcct gaattttgat ggaagagttt tttgcactga
     2881 aaaggcaagt cacttttata gttactttgc tcaaccagta ttattcatca cctattcact
     2941 tcgttcatag tgattctact cgctttgctc gaaaggaaac tcctttcgct ttgctcaacc
     3001 agtattgttc atcatctctt cacttcgttc atagtgattc acaataaaaa actctatgcc
     3061 accgcagaca tagagggact attgaatata ttcaataaac gtcctcggta ggaaattaag
     3121 gcttgatgcc acctactgtc ttcggtacaa gttaattatt aacctcaact agcttagcat
     3181 gctaaactag ttgagtcaag aattattttt cagttggatc aatcaacatt ctaatattta
     3241 attagaaaga agcttggtca acatggatac caggtccaaa tgttgttgtg atcgttacat
     3301 ttttcatgta ttgaccttta gctgctgatg gtttagcttt tagcaataca tcatggattg
     3361 ctgcaaagtt ttcaactaat ttttcatcgt caaatgaaac ttttccgatt ggtacatgga
     3421 tatttccagc tttgtccaca cggtaagtta ctttaccagc tttcacttcg tttactgctt
     3481 ttgttacgtc cattgtaact gtaccagttt tagggtttgg cattaagcct tttggtccta
     3541 atactcgtcc tagacgacct acagtagcca tcatatcagg tgttgcaaca actacatcaa
     3601 agtcaaacca tccgttttgg attttttgaa ccatgtcgtc gtcacctacg aaatctgcac
     3661 cagctgcttc agcttctttt gctttgtctc ctttagcaaa aactaaaaca gtttgtgttt
     3721 taccagttcc gtttggtaat acaacagcac cacggatttg ttggtctgct tttttagggt
     3781 ctacgttcaa acggtatgca acttcaactg ttgcatcaaa ttttgcaatg tttgtttctt
     3841 ttgctaaagc tactgcttcg gcaacaggat aaactttact tgaatcaact ttttttaatg
     3901 catcttgcat ttttttgctc tttttagcca ttttggttcc tccttgattg tggttataac
     3961 ggttgtacct cccacgtgtt ctatatcttt caatatagag ccaactgaga agctgctgtc
     4021 ttagggtgta tagattattc tacagtgatc cccatgcttc gtgcagttcc ttcaaccatg
     4081 cgcattgctg cttcaacgtt agctgcgttt aggtcttcca tttttaattc agcgatttct
     4141 cttacttgat cgctagaaac tttcgcaact ttatttttgt ttggttcgcc tgaacctttt
     4201 tcgattttag ctgctttttt caatagaaca gcagctggcg gtgtttttgt aacgaatgtg
     4261 aatgaacggt cttcgtatac agaaataaca accggaatga tcaaacctgc ttgatcagct
     4321 gtacgagcgt tgaattcttt tgtgaatccc atgatattga tacccgcttg acctagtgca
     4381 ggacctactg gtggagctgg agttgcttta cctgcaggaa tttgcaattt aacgattttt
     4441 tctactttct ttgccacgag acatacctcc ttaagtccgt gatgtggtta attggagatg
     4501 catatttctc ctcccacgtt ttatctgatc tgaaaaaatc cagacaaata atgtgcaaaa
     4561 caatgcacac tggtacagta tagcaaattt atttgttttt tcaagatttt tttctgctat
     4621 ttttacattt tgcttgaata aacgctaaat ttattctaaa aaaacaacaa tttttcgttc
     4681 tcatttcttc ttttatgtta cacttgcgct agcatggttc aacagatgaa agcaaacaat
     4741 aacacggttt tttagaccct tgtacaaaga ttcctacata acaaaatgag gtggagaaaa
     4801 tgaaagattt aaggtataga agtgtctttg atattattgg acctgtgatg attggtccaa
     4861 gtagctctca cactgccgga gctgctagaa tcgggaaaat catacgtagt atatttggcg
     4921 aacagcctga ttctgtagat atttatctat atgaatcatt tgcaaaaacc tatcgggggc
     4981 acggaacaga tattgcatta gttggcggcc tgttagggat ggaacccgat gatgaacgtt
     5041 tagctgattc tttgaaattg gcatatgaag ccggtatgga agtcttgttt gttcctaaga
     5101 gtgaaaaagc cgaacatcca aactctgtaa agatgcttct aaaaaaagga acacgaaagc
     5161 tttcagtcac tggcatttcg atcggcggtg gcaatatcca gatttctgaa ttgaatggat
     5221 tcaaaatttc tttaagcatg ggtactccta ccttgatcgt tgtccaccaa gatgttccag
     5281 gtatgattgc taaagtgact agtatacttt ctgagaccaa tacgaatatc ggcactatga
     5341 cagtgacacg ggaatcaaaa ggtgaaaatg ccattatgat aattgaagta gatgatcctc
     5401 aagtagaaga aacggtaaaa agactcaaac agctgccaaa tatcgacagc gtaaattatt
     5461 tcgattaagg agctaaaaaa atgtttttat cgattgaaga attagtagat caagcaaaag
     5521 cttatccaag tgtagcagaa ttgatgattg cagttgaaat ggaaatgagt ggccgttccc
     5581 gtagtcacat catcgagatc atggaaaaaa acctctcagt aatggaacaa tcaatcaacg
     5641 agggaaaaga aggtgttacc tccgtcacag gaattaccgg tggtgatgca aaaaaattag
     5701 atgattattt aaatgaggca gactttttaa gtggagaaac aatcttaaaa gctgtacgca
     5761 atgctgtagc tgttaatgaa gtcaatgcaa aaatggggtt gatttgtgct acaccgactg
     5821 ccggaagcgc gggtgttgtt cctggtgtgc tgatggctgt ccgagatcgg cttgatttga
     5881 cacatgaaca gcaattggaa ttcttattta ccgctggcgc tttcgggtta gtcatcgcaa
     5941 acaacgcttc tatcagtggt gcagaagggg gatgtcaagc agaagttggt tctgcaagtg
     6001 caatggcagc agcagctttg gtttgtgcaa aaaatgggac tcctcatcaa gcagcacaag
     6061 cagtagccat tacattgaaa aatatgatgg gactgatttg cgatcccgtt gcaggcttag
     6121 ttgaagtccc gtgtgtcaaa cgtaatgctt taggctcttc tcaagctttt atctctgctg
     6181 atatggcatt agcgggtatc gaaagtgtca ttccgccgga tgaagtcgtt gctgcaatgt
     6241 accaagtcgg acgtcaaatg ccgtcgattt tcaaagaaac agcagaaggt ggcttagctg
     6301 ttacgccaac tgctaaacga cttgcggaag agattttaaa taagagggcg tgataaagct
     6361 ccttaatttc gagtattaag agattagtta tcttcataac aaaaaacgaa gagaggacta
     6421 attgcccttc tcttcgtttt ttattaatcc atcaatttcg tattttttac ttcatcgatc
     6481 gtttttgttc ctgcaagttg catcgtgatc gacaattctt tgttcaggtg ttcaaaaaca
     6541 gatgttactc cttctgcccc acctagattc aacccataaa tcactggtcg gccaatcgca
     6601 actaagtcag caccacttgc cagagctttg aagacatgct ctcctcgacg gacaccagag
     6661 tcgaaaatca ctggtacacg tttgttgact acttcggcaa tttttggcaa tacttcaaag
     6721 gacgcaggac ctccatctaa ttgacgtcca ccatgattgg atacccagat accatctgcc
     6781 cctgcagaga tagcgattac tgcatcttct ggcgattgta ttccttttac gataactgga
     6841 agatgggtga tttctttgat tgttttgatg tcatctggtg tcaagccttg ttttgcagct
     6901 gcataaattt ctgcgattcc ttttccttcg ccattaccac ttgcactttg ttcgctatac
     6961 gcagctaagt taggcattgg taatggaaat tggaattgat tgatgacgtc ttcttcacgg
     7021 taaccaccga gcgttgaatc tgccgttaaa atgatagctt tagcccctgc ttctactgct
     7081 ttgttcaaaa tgaactcatt gaatctgtcg tctttactca tatataattg gaaaaactgc
     7141 ggtgcgcctg gcgctgcatc ggctgcgtct ttgattgtcg tatttgcata agtgctgatg
     7201 gaaaagattg atccagcagc agctactcct ttagctgtat cagcttcccc tttttcatgt
     7261 gccaatcctt gggccgctga tggcgcttgg ataatcggtg tatctaattc aattccgaaa
     7321 acagatgtat gcaaatcggc tgagtcgatt ccgcgtaata tccgtggcat gattttcttt
     7381 gtattaaaag aagtcgtatt ttctttcatc gtccactcat cttcagaacc accgcgaata
     7441 tagccaaaag ctcctgcttc catgcgctct tttacacgac cttctagtta ggcaatgttt
     7501 acaatatcga ttggatgttc ttcattactt gtatgataag tcatagtaga tccttctttc
     7561 atcttcttga ttacatataa atcatactaa acttacaaaa agtaagcaaa catttactct
     7621 cagatacttt tatcgctatt ctttccaaat aaatcgactt acaagctgat ctacttcttg
     7681 gttttcatga agcatactat gagaggcatt ttcacctgtc actacttttt cctctatttc
     7741 atttccgcgt tgcttcaaca acgcatagac cgctaatgca ctgtttaacg gtactgttcc
     7801 atcactcaag tctgtttcat ctagttgacc agcaatcaag aaaaatcgag tggttatagg
     7861 aatattaccg atcatttgct ggtaatcttg atagcggtta gaaacgacag caggcccctt
     7921 tgctaactca tctgtcagag actgcgcact atcatcgaca aaatcattaa aaggcgcgcc
     7981 aattgctgtt aatgtctgaa cttgtggcaa tgacgtatcc tgtccatacg ttcctaaata
     8041 gcgtagtgca ctaactcctc ccatggaatg ccccactatg ttgactttat ctatgccgta
     8101 gttttctttc agatacaaaa gacaagtttt gatccattct gcttgattcc actcgttatt
     8161 tttattatct tcaaacaata cttggaccat cggattgtct gcttttccag acaaatctcc
     8221 tgttgcttgt atttgtccat ctgttcctac tgttaaaacc aattctttta ctgcttgctg
     8281 atttttttcc aaacgccgca acatcccttt aaaggaattt tctgtcccgc tgtagccgtg
     8341 gaaaaaaagt gttggaatag tggttttttc tatcacttta ctggattctg ccgttttttc
     8401 tttatcagaa acttcagtag tatttatctt cgtcgtctgg caaccactta acgcaaacaa
     8461 actgataagg actaaagctg ctgcagttgc acgtttgcat aaatttttga ttggttctgt
     8521 catacacctc ttcctttcca tatagaaaaa agaaagactt gaaaggccaa tcatatgatc
     8581 gacatttcaa gtctctttat taatcgattt tatctacttg atcgaaatca agttctgtac
     8641 tggtttcacg tccaaacata tcgatgttga ctttcaattt ttctttttct ccgtcaactt
     8701 ctgttacttg tccttctaat ccagcaaatg cgccttcgat gattttcacg acttcgccaa
     8761 cttctacttc tagatcattt tgtcgcaggc tcataccgat agaacgcaag atatgattga
     8821 cttcttctgg aagtaatggt gctggtttgc ttccggctcc gtgtgaacca acgaatcctg
     8881 tcacaccagg tgtgttgcgg acaacatacc atgaagcgtc tgtcatgatc atttcaacaa
     8941 gtacgtatcc tgggaatgtt ttatgaacga tttctttttc tttcccattt ttgacttcag
     9001 tttctttttc ttcaggaaca acgacacgga aaataaagtc ggccattttc atactttgcg
     9061 cacgagattc gatatttgct tttactttgt tttcatatcc tgaatatgta tgcaagacat
     9121 accagttttt ttcaaaagat tccattgaag gctcctcatt tcattgtaaa ataaaaaaac
     9181 ctcagtacac ccgaagtttt tctttcgctt cattatagca ctaaaagtac gttgtggcta
     9241 gcgagttatt ttaaaatcca gccaaataag ctttggatgg ctgtatccat tacgtaaaac
     9301 atcaatccga aaataataga agtttcgatg actactaacg tatctttacg gagttgtttt
     9361 ctgcttggcc aagttacttg tttgatttca tcttttacgc tttttagaaa tttcatgaga
     9421 caacctccct tgctactgtt tatttcgttt ctttatgtaa tgtatattga ttacaatatt
     9481 tacaaaactt attgatttcc aaacgttcgc cgctttttcc ttcactgact gattttgtgt
     9541 agttgcgaga cccacaaacg gaacaagcga gtgctgcttt tttctttgcc atttacttct
     9601 gcccccttgc tgagaatcag acttatactt cataacagta tcacgtaact ttttacttgt
     9661 caatttgtga aataaactat ctattgtttt ggataaaatt atgatatgat taatttgaaa
     9721 ttaagctaaa atgagacaat tggaggtata gcgatgctat taaaaacact tgtatataag
     9781 aaaaaagatc tgacaaccgt tacagagact agtacattag aagaagcatt aaaaatttta
     9841 gaaacttccg gataccgttg tgtgccgatc ttagattctt caggtaatat tttccgtgga
     9901 aacatttaca aaatgcatat ctatcgtcat aaagcaaatg gcggtgatat gacgcttcct
     9961 gtcactcatc ttttgaaaaa cgctacaaag ttcatttacc tggatacttc tttcttcaaa
    10021 gtattcttta cgatcaaaga gcttccttat attgctgtcc ttgacagtga aaatcatttt
    10081 tatggtattt tgacacatag tacgttgctt aatatgctct ctcaatcttg gagcgtagaa
    10141 caaggaagct atgtactgac aattgcttcc acaggaaagc aaggagattt ggctgctatt
    10201 gcaaaaatca tttcaaaaca cagcagcatt gccagctgta ttactcttga tatcgaaaaa
    10261 gacgaataca ttcgacgtac attgatcacg ctaccggcta acactgaagc gaaagtatgt
    10321 gaaacgatcg tcaaccactt agagaaaaag aattataaag tggtagaaat tgaaaatttg
    10381 caaaaccaag aagcataatc aaaaagcgaa aaaagaaaac agctaatctg ctttcttttt
    10441 tcgcttttta taattagaca cgcttttcaa aatcaagcgc gcgatctaaa taatacatca
    10501 atggtgctga aacagccatg acgataaact cacttaatgc aagcgtgcca taggttgtcc
    10561 aaaatgcttg gccacctgtt ggaactaaca tataagcaat cagtcccatg ctgatggtaa
    10621 agaagatcgt gttcaatact aaacgcatct ttacattttt cactttgttt tgcaataaag
    10681 ctgtcaggcc taaagaaagc aatgtttggc cgccaccaaa aaccacatcc atgataccaa
    10741 aaccaaagaa ggcattatag acgatgaccc cgcctaaaac tccccaaagc aatttacggt
    10801 taaagacaac taaatgattc aaactttctg aaatacgaaa ctggatcggc cctgaggata
    10861 caggcgcaac taaaatagtt aacgctagat aaagagccat gatgatgcca tttacaacga
    10921 ttacggataa ccgttgtctg cttttcgttt tttgcatttt ctctcctctt ttctcctagt
    10981 ttttttaacg cgggatggtt gatgaaccgc ggttatgtga aacaaacaat aattataaca
    11041 gacttttcat ttatttcaat ccgtcttatc tgcttttaaa aaagcaaaag cttaaacaat
    11101 gtaaacgttt gctaaaaatc gtgggatatg gtataaagta agtgtaaggg gtcataagaa
    11161 ttcccagtaa agcagacgaa gtaggatctg caagaacaga attgttgtga aacttaaata
    11221 aataaaaaag gatgtgggaa tttgagcaac ctcttactag agaacggtct agcaagcagc
    11281 tgaagatcta agtggacatg ccgaaccttg gaacttctcc ttacgtaagt aatggatcat
    11341 gcgcttgcta ggcttttttg tgtttttcgg tcttcggacc tttttcattt tcctagactt
    11401 ctgctataat aaccaagaat taattttgta acagattttt ttgaaaaaac aagtttcttt
    11461 cattcaaaaa atagaaaaag cttgctaatt attggttaac cagcaaacag gagtattaaa
    11521 atatcttgtt ttattgaata gcaggaggaa atcatgaaat tccattatca tatattgatc
    11581 aatccatcgg caggcagcgg aaatggctat aaagtagcag aaagaatttt accggtatta
    11641 aaaaataagc atattgacta tacacttcat tatagtgaat acaaaggaca cgatgctgag
    11701 attgctgaaa ctttggcaaa agaaacattg attccttgga tagaagaaga acagaaaaca
    11761 atcgatactt tccccctttt gatcatcgta ggaggtgacg gcaccttaca tcaggtactt
    11821 gatactttct atcagatgga agtagaattc ccagttgctt atattccagc aggttctgga
    11881 aatgattttg ctcgaggggc aggccttcca aaaaatccca aaaaaggact tcagctgatt
    11941 ttagcagctc aatcaccaga aaaagtccac ataatggctt atgaagaaaa aataagtgaa
    12001 aaaaaaggaa tagctgttaa taatttcggt ataggattag atgcagctat cgtccatgcg
    12061 acaaatcatt cttccacaaa aaagcgattg aacaaataca acttaggatc attttcgtat
    12121 ttattctcta ttctccgtgc tttattcact caaaaaggat ttccaattct ggtagatgca
    12181 ggaggaaaac aattaagttt ttcaaacgca tttttatgta cagcaacgaa gcatcctttt
    12241 tttggcggag gaatcgcgat tgttccaact gctgatgcgt ctaaaccagt cattgatttt
    12301 gtcgtggtcg aacgaatcaa tttctttaaa atcttgtggc tcattctttt acttatacag
    12361 aaaaaacaat tgaaatcgaa atatttccat cactacacaa caaacagatt acgtatcgtt
    12421 tcaacaacac cgcaacatgg tcaagaagat ggagaagaaa tggaaaaacg accttttgat
    12481 atcacaataa ccacaactaa acagttgttt tggtgttaat aaaagaggtt ttgtcagaag
    12541 ctacatctgg aacaccgttt attcggaaaa aaggactgtg acacgacttt tgtcacagtc
    12601 ctttttttac tatgcagtta attctttgcc caattgggtt gccatcgata gtttctttct
    12661 ttacccaaaa taaattggat cattgaaaac accgcagcaa aagcaactaa gacacaacca
    12721 ttgaaccaaa aagattctgc aaatgtttga ttgtaactga gtgtttcact gatcaagtta
    12781 ttattttgaa caaaccaata tgttggtgtg aatgccgcta ttttgctaac catttctggc
    12841 aagtattctg ctggtacaaa caccccaccg ataaagcaac tgcctgtgat aaaaatatct
    12901 ttgatcccac cgctggtttc tgagtttttt accaatgaag tgatacaagc cgaaaagcta
    12961 atgatcggca ataaaaacaa gaaagtattt aaaatatgat accataccgt tatatcccac
    13021 gaggtgtgga tcactaacag aaccattaga agtaagaagc cactgaacaa cagcagcgag
    13081 taactaatca aactaaaggt tactttgcga ttcaagtttc gtttggtaat gggcgcactc
    13141 tggtttcgtt tactgatctc tttgcgatta aacgctagat tgatgacgct gaaaccgcta
    13201 aaaatggata gaaacaaccc ataagacaag aaattaaagg ttgtgcccgt caacagcttt
    13261 ttcatccgct gactatatcc cgcacttagc tcaacttctc cagtaaccga gagtgccatt
    13321 tgtgtctgtt ccatagctgc atcgattgtt ttatcttctt cttgaaacag aatcagtgtt
    13381 tgcaaaaagg tgttcacttg ctgtgtaaca actgttttag aaaaggcatc tgggcgactc
    13441 tgtatcttga tcgtcgccat ctttcctact tcgacttgtt cggtaaagtc tgcaggcaga
    13501 tgtaagataa tgtttacacg attaaaataa agagcatcat cgatttcttt ttgtgaggtt
    13561 ccatccaatg taacgactgt ttccttgtca ttcaaatatt tacgaaggcc atcgactaca
    13621 ggcgactctt cttcactaat caaggcgatt ttcgcatctt gcagagaggt attttcaaca
    13681 tcaatatttt gcgcaaaaaa gaatgtggca acaacagtga taattacacc tatcagtaaa
    13741 ttcgatttat ttgctttaag caatgtccaa atcgttttat aaagcgtcat aacgcacccc
    13801 tctttccatc caagcatttc ctaacgcaaa aaggaaaata aatccgatca accatagaag
    13861 attggtataa aaactagcca aatcagtgta gaaataaagt ttatacaaac tttcgctgat
    13921 caagttgacg agatttaatt gaccaacaat cggaatatga agatcaatcc aatacttcac
    13981 ttgttccgac cccatcatac cagcaaaaaa gctcatcgca atcgtcactg aaatcaagat
    14041 gctatccttt tgcaccagat tcatttttgg tatcaaatta ccaaccaatg tacctaacaa
    14101 aatcgcacac aacgacccca gagcggtaac aatcatcaac cattgccaac gttcaccaaa
    14161 gtctacttga tagataaaac gaaagacagc taacataata taaatctctg tcaaaacaat
    14221 cgtaaagctt gctgccaaat tagcgattga aactaacgat tgctttctag gaatcaagga
    14281 caagcgaata ccatttgacg attgatttgc ttgctgatcc tgtacattgc ggacccccca
    14341 catcgtcccg tagagaatcg ccattccaat cagagtgaag aaataaaaac ttttgaaact
    14401 catattacga cctgcatgaa cttcttgaaa agatacttct tgttcaaaaa cagtcatgat
    14461 gggcgcgaga tcaacgttct ccacttctgc cactttactc gaaattatac caatacgctg
    14521 taaaaattga tccatgacgt ttttcatcaa cgtctgactc attcctgctt gacccacatg
    14581 gagcgaaaca gatgaaccat caatgagata aaaaccagcc aaatcatctg catttagctt
    14641 ttcattcgct tctacttccg atagttcctg tacttcaaat aatggtttat cattgacttc
    14701 gacttgttct aagactgtgg taaaattttc cgaaagcgct gtttgatccg ctttgattac
    14761 aattccagta ttaatcgttt caagattgcc accttgatca atctcgccaa aggccgccat
    14821 aaacatcaat cctaaaagaa ttggaaaggc caatgtccaa aacaacatgg atttatttcg
    14881 cagcagtatt tttgtgcgat atttataaaa atgccaaaac attatttccc ctcctctagt
    14941 ctctcaaatc cttgccagta atctctaaaa agacatcatt caaggacgct tctttggttg
    15001 ctatttttcc gtaactgatc ttttcttctt gtaagattgt aagaatcggc aacaatactg
    15061 tatttagttc agtagttgtt acttggagct gacctttttt ataagcgatt ccatcagaag
    15121 ctattgttcg ctgaatcgct gacaacacat tttctgggag taatgggatg tcgatcgtca
    15181 aacgatccgc cgtccgtacc atatctttta gagattcttt ggttccttta gcaatcacct
    15241 gtccttgatc catgatcacg atctggtcgc aaagaatttc tacttcttcc atgtaatgtg
    15301 ttgtatagac aatggttgct ccttgtcgat tcagctcctt gatactttct aaaattttat
    15361 tccgactttg ggggtctaca gctactgtcg gctcatctaa aaaaattaac cgcggcttgt
    15421 gggcaatccc acatgcgatg ttcaaccgac gtttcaagcc accactaagt tctcctggac
    15481 gaaacgaaac atatttttct aatcccacta attgaatcac ctcttcaatc aaggctttcc
    15541 ttttctcttt ttcggaaaca tataaaccgc aaaaataatc gatattttct tgcacactta
    15601 gttcgtcaaa gaccgcaacg tcttgaggaa cgaccccaat cattgccttg acagcataat
    15661 tttcaggagt cattgttgtc ccgaacaatt taatggttcc tttgtcataa tttaacaaag
    15721 aaagcataca gttgatggca gtcgatttcc cactgccgtt tggacctaac agacctaaga
    15781 cttctccttc ttgtacttgc agatcaaaat gattcaatgc tacaaaatct ccatagcgtt
    15841 tgactaattt atcaatttcg ataatcatca tgaaaaactc cttccaaatt tcttgttgat
    15901 ctgactataa taaagtgcaa gaaaagaaac tagtgacgat tggctaaacc acacatgaca
    15961 tttgtcacaa tgaaggagtc tgctatgcat aaatctcggc tactcaacga aactagcttt
    16021 ctactggtta tctcattgct tttgctggta agtcaaggat tcgttgctat gcaagttatc
    16081 tatttattga tcgccgtttt attcactggt gtcagttatt tactgcctac aaagccaaat
    16141 tggattttcc aagttattct atttctttta tgtgcctttt tacctgatct tgtcctgttt
    16201 ctgccagcga cgatgcgagt gatcgcccct gaagaaagcc accttgatta cttgtttttg
    16261 ttaggttttt tgttgatttc gacggttggt aatcatcccc ccatcaaggt cgcctttgtc
    16321 gtaattttgc tgtttttttc cttttactta cgaaaaaaag atcaacgaac gaccgatctt
    16381 gagaaaaagt acattgtctc caaagatact cattgggaaa aacaacaaga gttatcggaa
    16441 caaaataaag cattggccct gtcacaagaa acacaattag ccttgcaaat tgtggaagaa
    16501 cggaaccgaa ttgcccgaga catccatgac aatgtcggtc atctgctgtc aagtgcgatt
    16561 ttacaaattg gtgcgcttga aatgatcaat caagaaccaa aactaaaaga accattagaa
    16621 aatttaagtg ccaccgttca cactgggatg gatcggattc gtcaaagtgt ccatgacctc
    16681 catgagacat cgatctcttt tcaacactcc ttagagtttc tgatcgctga ttttccttct
    16741 tctgttacga ttgaaggaaa cttgtttgaa ggattgaatg aaacgcagca aaactgcttc
    16801 ttaatggtca tcaaagaagc cttaaccaac agtatcaaac atagtcatgc caaaaccgtt
    16861 gttttacatt ttcgaacgtt gccggccttt tatcgcttgc aaatcacgaa tgatggcacc
    16921 agcccacaaa aaaattctgc tcccggtatt ggtttgaaaa cgatgcgtca acgtgttcaa
    16981 gaacaaaagg gacaagtcca tattttccaa gaaaaccagc aatttcagtt aacgatcatt
    17041 ttaccaaggg agggacacca atgataacag tagtcattat tgatgatgat ccatttgtga
    17101 cgaaatcgtt acaaaccatt ttagaaagca cgaaagagat ccgtgtgtta ggcattggtc
    17161 attgtgccaa ggatgcgcga aacccatcgt cccgatgttt tgctgacgga catccgcatg
    17221 cctaaacaaa cgggcatcga tgctgccaaa gaaattttgg ctaaatttcc caaagccatc
    17281 cttttgcttt tgacgacatt caaagatgaa gaatacatcc gcgaagcatt ttccatcggt
    17341 gtcaaagggt atttaatcaa acagaacttg caagcgatta ttccttctgt caaatccgct
    17401 tataatggac aggccgtatt tggtaatgaa atcatcgaga ctttcactca aatgatgaag
    17461 aataaaccga cgattgatag tcatgcttat gcttctttta gtgaacgtga gcttgcaatc
    17521 atcaaagaag tagctgccgg gaaaaacaat aaagaaattg cagatgcctt gtacttgagt
    17581 gacggcactg ttcgcaatta catcagccaa ttactagaaa agctagattt acgggatcgc
    17641 acgcaattgg ctatctattt ttatcagcat ttgcaataag tcttatctaa cacaaaaaaa
    17701 cctgaatgat gctccttcgc atcattcagg tttttttcac atcttctatt caattgtccc
    17761 gcaaaccatt tcctcacgat tgaaagaatc aaggattcgc agggctgcca ggattcgttg
    17821 gattgttcgg cgtgttaggc ggaaaaatag gcgccttgtc taacgttttt tctagttttg
    17881 attcttcacg atcgtctcgt tctacatcag gactttcatt caatttgaat tctttttcca
    17941 tctcatctaa ctttttaaag tcattgccag attcttttgc taatttcgct aatttatctt
    18001 cggtttcttt agccataaag taacgccccc cttttgattt cagcttagca tatcacactg
    18061 aaaaaacaaa agaaaacgct aaccaacgat catttttagc tatttctcat ctttaaaatc
    18121 aagcattttt tgccggtata aaatcgtagg gagaactgtt ttccatacca atcatcggat
    18181 ctactaactg gttatcgatc acttctgctg taagaacgaa atctttagaa acagcaggtt
    18241 ctacctcttc tttcttttct tctccaacaa atgaagaaaa cagatctggt tccactgttt
    18301 ccattacttg gtttttcgtt tcattcgtcc cactgtcatc ttctacaggt agcttttctt
    18361 ttacaacccg tggctctttt gtatagttcc catcttcaaa tggatcattt ccgaccaaag
    18421 aatcttcata agctgctagt ttggtccgga gagtgatatt cattttatca ttatccatga
    18481 tccttgattt caacgtagtc atccggcttg ctgattcatt cgctacacaa gtgacatagg
    18541 cttgctcttc ccctaacaaa atcaacagtt ccttactgcg agtcactgcc gtgtagagca
    18601 aattacgctg aagcatccgc tgatattgat ggaccatggg caaaataacc atcttgaatt
    18661 cactgccttg tgatttatgg attgagcaac aataagaaag agtgatttta ttccattcgt
    18721 ttcttttata agtgacctca tttgcatcaa actggataac taattcatcc actttatctt
    18781 cagaatcttt tgccaagatg atacccgtga tttctcccat atctccattg aatacattca
    18841 attcgggagt attgactaat tggaggactt tgtctcctat ccgataaacg gtgtcgttcc
    18901 aatgtacttc cttttttcca ggtttccctg gattgaatat ctcctgcatc attttattta
    18961 acgcatcgat ccctgcaggt ccccgataca ttggtgctaa tacttggata tcttgtgcac
    19021 ggaatccctt atttttcgct ttttccacaa ttttagagat caagggttca atttgataag
    19081 catcacttcg gaaataggaa cgatcttttt gattctttgt gaaatctttt ggcagacgtc
    19141 cttctttgat ctcatgggca agaggaataa tactagaacc atcaccttgc cgataaatct
    19201 gattgagttc cattttggga atttgttcga tttccaaaag atcatggagt acttgaccag
    19261 gaccgacaga gggaagctga tctttgtctc ctactaagat aacttgcata ttcgtcggaa
    19321 tcgctttgaa taatgtgtta gccagccatg tatcgaccat agacatctca tcaacaatca
    19381 aaagtccgcc ttctaattct ttcgtactga ctgaaggtgt tttttcccgt ccattcagcc
    19441 ccagaagacg atggatcgta ctggcaggca gacctgtcgt ttcgttcatt cgtttagctg
    19501 ctcggccagt tggtgctgca agtagaatag gaaaaatttc ttgggtatat tttgaaggat
    19561 ccaattccag tccgttcaac tctgcaaaaa gattgacgat tccgttgatc acagtagttt
    19621 tccccgtacc tggtcctcct gttaaaataa atagagggga acggattgct tcagcgatag
    19681 cttgttcttg cgaaggtcca tactgtatgc cgaatatttt ttcgatacgc cgaatattct
    19741 tctgcacttc tttttcagga taatggattt cttttttacg actgagaagg cgctggatcg
    19801 aattaccgat cccccattca gaaaagtaca aactgttttc gtaaagatta gtctcttctt
    19861 gttgtatctt tccttcttca acaagttgga taattacagt agcaacctga tcaggctgga
    19921 tttcaattgg gcgacttgtt tctaaaatac ggatcgtttg ctgaagcaat gtctccgccg
    19981 gtacgtatgt atctcctgtt tgaactgcat gctgaaaaat ctgatgcaag atagctgctc
    20041 gaattcttct cggtgaatct gctgcaatac cgatttgttc ggctagatta tctgcacgtt
    20101 tgaacccgat tccttctatg tcttcgacta gctggtacgg attttcttcg atgatatcca
    20161 aagactcgtt cttataggcc tggtagatac tgaaagctaa ctgactaccg aacccgtaac
    20221 gattcagtcc catgatcact tgatccatcc cgtggtttag ccgaatcgtc tcagcaagca
    20281 tttctctttt tggcttcgtc aaaccggaga tttgttttaa taccgaagga tcagcaatga
    20341 ttttttcgat agcatcttct cccagcaatt ctacaatttt ttctgctgtt ttcttcccga
    20401 ttcctgggaa tttttcgctg gaaagatacg ctacgatccc atttgcagtt gttggctttt
    20461 cttgctcata tctttcgagt ttaagctgcc ttccgtattt aggatgatcc actaattctc
    20521 cataaaaacg ataagtctca ttttcttgaa tatcgccgaa acttccggtg actacaatct
    20581 ctttttcacg gtaatcagct gtggtttcac tgatgtgtac caaaagcact ttgtaaaaat
    20641 tactaggatt ttgaaaaaaa atcgcggcaa ctgtaccaac gaaataaggc atttcttctg
    20701 gctgcatcgg aagccgcctc cttcttctat agtaaaggtt ctggtgctgt ttcagttcct
    20761 aaaaaatctg tttggttcca tactttcagt tcatatggca ataatctgca aggctcttca
    20821 gtctctaaaa tcgtcaaact actattgaac aatccaccca tttcacgcaa ctcacttagc
    20881 tcttttcctg tcatccattg aatggctgca gttaaagaag ctccatgtcc tacgaataaa
    20941 agtgggccat ctttatgtcg ggcaaccgca tctgctacaa cagtttcgat acgtgtgatt
    21001 gccgattcaa tcgtttctcc gtgaaaagga gaaggatcat acagatctaa atgattacgc
    21061 aaattcggca gattatccgg atatttctgg tacatttcat cgatcgactg accttctaaa
    21121 gtacccagcc ctagttctct tagcttatct gtataaaaaa tctctaccgg acgagcaagc
    21181 tctttgttga taccttctgc tgtatcacgt gctcgctttg ctgtactgga ataaattgct
    21241 ttaaaaggaa catattttac ctttttccca aatgctttga tttcttcgta actttgtggc
    21301 aaaagcggag aatcgccatt gctcccttga aaacgtcttt cctgattcca ttgtgtcttc
    21361 ccatgtcggg taaaatatag ttccatacgc agcaaactcc tgtctttctt ttattttact
    21421 ctataataaa ctgtctaatc cagcttgtca ttttcatagt gatgcgtcaa ttctaaatta
    21481 gggaatcctt gctggcgaag tgcttcatac actatcattg cagctgtatt cgataaattc
    21541 aatgagcgga catgctcatc attcataggg atgcgtaaac acttttcttc gttttcacgc
    21601 ataaatgttt ctggcaaacc ggttgtttct tttccaaata aaaagaagtg ctcttctcca
    21661 tcagcaaaat tttcgtcact atatacttta tgggcaaatt ttgagatcaa atgtagttta
    21721 cgattaccta aaaatgttaa aaaagcttct aaattactgt ggtaagtaat atttacatca
    21781 ttccaataat ccaaccctgc ccgttttaga tgtttgtcat cagttgaaaa acctagtggc
    21841 tcgattaaat gaagcggagt attcgtggct gcacacgtac gggcaatatt tccagtgttt
    21901 gcagggatta atggttcaaa taaaacgata tgattcatca ggatcattcc tctcatattt
    21961 atgttcgttt ctattttctg acaatttgat ttttgcataa aaaaaaacgt atcaactcgg
    22021 tgtcagtcac tgcgagtcgt tacgttagtg aagctcttct cactaacttt tatcagaaca
    22081 ggaacctgat aaaaaccaat gaaaaaacaa cttgttgcta atataacacc ctcaactttt
    22141 ttttgcaacc tctactcatt aaaaactgct agaaaaacgt tttctcttag ttccttttaa
    22201 taattctatg tcaattgtaa tcttcttcaa aggattctta tataagtctg ctttgattcg
    22261 ctcttctacc tgccattcta aaggtgacat ggccaaaaga tctttttgat tttcctctgg
    22321 tatctcaaat tcataggtta cacgctgacg ttcagttaat ttcattgctt cagcaaactt
    22381 ggctactaca cgttcattgg aataactctg tttttcaggt tgattcggat aaaaagcctg
    22441 acgtagttcc tttaaataat tttcttgtgg caccaccttc aacacttctc catcttctga
    22501 gagtacacgt tggaattctt ggtaatgaga aggcgaaaag atatttaaaa ccgcgttgaa
    22561 tgtttgatca gcaaacggca aattggtcaa atcagctaca caccaaaatg cttcggcaga
    22621 ttgttctgta gctgcgtaga ctccttcttt tgaaatatca aatccaacag cattttgaat
    22681 ctttttcaat tttgaaagtt cattcaagaa gctaccttct ccgcagccaa catctaatag
    22741 cgagacttct tcaggtaaat gctgcgcaat agtctcaata acgggctgat acatgccaga
    22801 ttggatcatt ctacgccttg gaacgaacat tccttgatcg tattctgttt taaccgcatg
    22861 ggataaaaaa taaagtgttc cttttttgga aaggtcaaaa cggtgattat ttttgcatat
    22921 caagccatta tcagactttt ttacttcttc ttggcaaacc ggacagcgga acagctgatg
    22981 attttctgcc aaaaactggc gtcctcggtc aatttttttt aacatagttc cccctcattt
    23041 ctgttttatc ttaccgttag atgctcactt tggcaactgc taaaaatatg atacaatgcc
    23101 tagaagaaag tgaaagataa aggagaagat tagatgatca aagaattttg cgctgaaaac
    23161 tacacatcta ttcctctagc aattgctaga ggagccgatc ggatcgaatt gtgtgacaac
    23221 ttagcggtcg gtggcacaac cccgagtact ggtgtgatcg aagaaacgtt aagttatgct
    23281 ggggaaaaag atatccccgt aatgacgatt attcgtccta gagggggcga cttcgtctat
    23341 aacgatatcg aattgaaaat catgcatact gatttgattg aagcaaagaa attagggacg
    23401 gatggcgtag tatttggttg tcttactcct tcaggctggc tagacgaaga ggccttagaa
    23461 ctattgatcg aaacagcaga agggttgcag atcaccttcc atatggcttt tgacagtatt
    23521 cctgaagatc ggcaattcga agcaatcgat tggctggtag aacatggtgt tgaccgtatc
    23581 ttgactcatg gcggtcctgc tgacaaaact attgtagaaa atttcccacg gcttaaagaa
    23641 ttgattgcct atacagatgg ccgcttaatc attttgcctg gtggtggtgt cactgcagag
    23701 aatgcagcac atgtagctaa agaattgaac gtaagcgaag tacacggaac caaaatcgtg
    23761 gatcttcagt tataatctta taaacaaaaa aacatttgca acaggcataa tgcttattgc
    23821 aaatgttttt gtttttttac ataaaatagc ccataaataa agaagcaata ttgaaataaa
    23881 tcagtacact cgtcaaatcg ctcaaagtcg tgataaaggg accgcttgct actgctggat
    23941 caaatcctag acgatccatt agcatcggga ttaaactacc tgcaagattc gccactgtga
    24001 ttgcaaatag catagccatc cctatgacaa accccaagat aaaattatgt ttccaaaaac
    24061 ctacgattag aaaaatcgtg atccccgtaa cagctcctgt gacaacgccg gtcaagactt
    24121 cagccaaaac aagtcgaaca aatccatgat ctttctcatc agaaatcgca agtcgacgaa
    24181 cagccacagc tagcgactgg gttccagcat taccggcagt tcctgtaatc agcgaaatga
    24241 agactgctaa aatactcgct tcacttacca agtcttcata gtgactgatt aaagaagcgg
    24301 tcgacatacc taaaaacaac agagtgatca gccaaggcaa acgtcgagac gctgccttta
    24361 ctggattttc attaatttct tccacattga ccccggcaag tcctgaataa tcgctagcag
    24421 cttcatcatc aataacgtcg atgatatcat cgactgtgac gattcctaac aaatgatcat
    24481 cataatcggt aacaggaaga gctaagaagt cataatctct aaatgtttgt gccacatctt
    24541 cttggtcgtc gcctacatga actgaaagca ctcgttcgct catcagatca gaaatcattg
    24601 cgtcgtcatc attcacgatt aggtcgcgca gagaaataac ccctactagc tgaccttctt
    24661 gattaacgac atagatgtaa tagattgttt cagctacatc tgcttcgttc ttcagcacgt
    24721 acatcgcaga gcgaacagtt tgattggcta cgatcgaaac aaattcagtt gtcatgatcg
    24781 cgccagccgt ttcatcctcg taatggagaa gttccttgat ttcactggca tcgtctgccg
    24841 acatcaaact taaatattta gcaatttgct ttttatccag cgtattaagc aagtcaacag
    24901 cattatctgt atacatctca gaaagcatat cagctgcata gctaggacgc atttcatcta
    24961 ggtattcttt catatgttcg ttgtcttctt caatcacatc gaacatatcc gctaattctt
    25021 taggcgacag ataggaatag atcagctgcc tgttctcttc tgtaagagat tggtagaatt
    25081 gcccctgctc atagatatgc atctctaaaa aactgtttct gaatgcctga atattatttt
    25141 cccttaaatc ttgagtcaac tgggcaaatc tttcctctaa ttcttgattt tcatccaaac
    25201 caatctcacc tcgccttatt cttcaaaccg tctcacaact gcctccatgt ctgcggctaa
    25261 aggctgcttg aactccagca actcttctgt aaatggatgg taaaaacgca gatcataaca
    25321 atgaagggct tgtcttttta ttcccagatc cattcgcccg ccatacatat catcaccgag
    25381 cagggcacag ccaattgcgg aaaaatgaac tcttatttga tgtgtccttc ctgtatgcag
    25441 ctggatatca actaacgcga tttctgttag tcgcttctct atccagtact cagtctgtgc
    25501 cgaacgtcct tcatcagaga ccattcgctt caatagcgaa gaataatctc gggcgatcgg
    25561 caaatcgata tgtccatgtg ccgataaatc tgaaagcctt ccactgacta aggcctgata
    25621 ttttttcaca aacttctttt cacgaagttg catatctaat tttgcgtgcg caaatccatg
    25681 ctttgcaaaa agcatcaagc cagatgtatc ccgatctagt cgcgtcacca catggattac
    25741 ttggttttcg taaccttgtt ttttataata agcctttaca cgattagcca ttgtcccatt
    25801 tggatggtat tgggcaggaa tagacgaaac gcctgctggt ttatttacta ccagaacgtg
    25861 ttcatcttca tacacgatat cgatcggtgt ttcatccaaa agtacggttt catgttctcc
    25921 ttcagcagga atcacaatgg ttaccttatc atccttagct agagaaaaca agacattttc
    25981 tacttgatca ttaactttga tttgaccgcc ttgaaatttt attttcgcta acagaccctt
    26041 tgagatccct ttttctttta aaaaatattt tacttgctga gaatgatctt tctcataatc
    26101 ccatgtaaac tgcatatcaa tcctcactaa taaaggcatc tttcacacga tgccaaaaat
    26161 gcatatgtcg ataagaagca aaatggatcc gttcttctgc tattcgataa taaattgagc
    26221 ggatatttgc ttttgcgaca ttcaattgat caaccgttac aagataatct tctgtatttt
    26281 ccaattttat ttctagccat tcatcatggg caatcacgat cggagaaccc aaagtacgaa
    26341 acactcgatt attcagtgaa gcaatctctg ccaactgaaa ggcattgata ctaggatgga
    26401 tcacagcacc gccgacactt ttattatatg ctgtcgaacc agtaggcgta gaaatcgtca
    26461 atccatctcc tctaaaactt tcaaacagct cgtttttgat gtatacatcg gctaccatcg
    26521 tacgattggc ccgtttaatc gttgattcat tcagtgctaa aaaatgctgg tccggtgttt
    26581 catccaaata actgatccga acatccagca agggataact aacactttgt tcccggttcg
    26641 ttcgtaagct gtctactagt tcttccagct cgtaatcccg ccaatccgtg taaaacccta
    26701 aatgacctgt atgcacgccc aagaaacgca catcattcag acaatgactg tagtgatgga
    26761 acgccgacaa taatgtgccg tctccgccga ctgagatgac caattctggc tcatgatcat
    26821 ctcgttgaat ccctgcttgt tctaaaagtg cgttcaaacg ttctgtcact tctatagtct
    26881 ttgcttcttt attatgaacg atcgctactt tcatcccctg cctcctctct ttcgctttct
    26941 ttcttcaaaa gcgttcgata gtagacatca tctgattttc ctcttccatg ggagaataac
    27001 cgctgtgctt cttggatttc ttcacggata ctggacatct cttcatccaa ctgataggca
    27061 gcttctgccg cacgctgaag tcgttcactc atttcttctg gaaaaacgcc ttgatattta
    27121 taattcagcg aatgctcaat cgttgcccag aaattcatcg caagagtccg aatctggatt
    27181 tccgccaaaa ttttcttctc accgctgatc agctgtacag gatactcgat caccagatga
    27241 taagaacggt agccacttgc ttttttattt gtgatgtaat ctcgttcttg gagaactttc
    27301 atgtcttttc ttttacggat gatctcaaca acttgatgga tatcttctac aaactgacac
    27361 atgatcctta acccggcaat atcagacatt tcttcttcta aacgtcccat tggaatatgc
    27421 cgtaattgtg attttgttac aatactatcg actggcttga ctctcccagt gacaaattca
    27481 atcgggacat gtcgattttg ttcacggaac tgtttgcgga tcccccgcag tttcactttc
    27541 aattctgata cagtttgttc atatggtgct aaaaatgctt cccaatctcg ttccatagct
    27601 gatacctcta cttcattaac attcattgtt tattctacca tatatgcaaa gttttttcgt
    27661 actcttgatt tatgcattga ccaaaaaaag aaaattaggc aaaatagaca aaaaggagtc
    27721 gatcaaatga cacaaatgct tgaaatcgaa tataaatcta tgctgacaaa gcaagagtac
    27781 gagatattca tcgctcacta tcaattaaca gataaagatt tccgtgtaca gactaatatt
    27841 tatttcgata ccgttgatga acagctgaag aaacaaaatt gtggcctacg gatccgtttc
    27901 gttggtcatc aagctgaata tacattaaaa acacctgctg aaaaagggcg tctcgaaaca
    27961 acggatacct ttataacaga agaagcagaa gcatttatct tcgaaaaacg tctgcctcgt
    28021 tcaggcgcag tttttcaaaa actttctgat ttgaatatcg atcctgcttc attaatccaa
    28081 accggaaagc ttacaacaaa acgagctgaa ttccctattg aagaaggact tttagctatt
    28141 gatgaaagct ggggagacaa tctacacgat tttgaactgg aactagaggt aggggatgca
    28201 tctgtgggaa aaattgcttt tataaatttt ttaaaacgtt tttctttacc ttatcgtcct
    28261 gctaagaaca agatccaacg tatgcttgaa gctaaaaatt agaaaccttt cattttcaca
    28321 aggcacttga gttcattttt ttactttttt ctgttaagtt ataggatgtg aaagaatcta
    28381 gtcactagtt gtatagaatc tattttgggg gagattcata tgatcgaaat ctatttattt
    28441 gttaatcctt taggggaata ctgtttcgaa atggaacaac agttattaca atttatcgaa
    28501 gaagagtacg ggacaccatc aaaagaaaag atgcaatttc gctttcttcc tttggtcaat
    28561 ttgcagacaa ttggggatgt catgcaacaa aaaggaattt ctcagaacaa tcttgaggaa
    28621 cgtaatcact tattctcaat gacttattct gcagcattgg actgcaaagc ggcgcagttt
    28681 caaggaaaga aaaaaggccg ccgttttttg atcaaattgc aagaagcagt cggctgtaat
    28741 gacataccat attctcaaga acttgctgaa tccatatttg aagaaatcgg cggcgatttg
    28801 aatatgttta aagaagatcg tcagtctgac ttcgttaaag aagtattctt ttctgatcaa
    28861 aaaattgctc gggaaatggg catcacaaaa cacccttctg cagtcgttta caattatgcc
    28921 tgcgaccgtg attttggtgt tttagtagaa gtaaaaggta caagtagcct ttggagaatc
    28981 acagagctgt gtaaaacaac agataactca tatcaagttt ttaatggtga acatttacat
    29041 acaaatgatt ctcagttcca ttcaagaact agccatttac acttgctttc taattaaaa
//
LOCUS       DACGEU010000029        28841 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.029, whole genome shotgun sequence.
ACCESSION   DACGEU010000029 DACGEU010000000
VERSION     DACGEU010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 28841)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28841)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28841
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.029"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            4..672
                     /locus_tag="IXR40_001201"
     CDS             4..672
                     /locus_tag="IXR40_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAQ4361062.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            complement(963..1703)
                     /locus_tag="IXR40_001202"
     CDS             complement(963..1703)
                     /locus_tag="IXR40_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361063.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
     gene            complement(1833..2780)
                     /locus_tag="IXR40_001203"
     CDS             complement(1833..2780)
                     /locus_tag="IXR40_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAQ4361064.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVLSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            complement(2909..3673)
                     /locus_tag="IXR40_001204"
     CDS             complement(2909..3673)
                     /locus_tag="IXR40_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAQ4361065.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            complement(3677..4066)
                     /locus_tag="IXR40_001205"
     CDS             complement(3677..4066)
                     /locus_tag="IXR40_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361066.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            4201..4743
                     /locus_tag="IXR40_001206"
     CDS             4201..4743
                     /locus_tag="IXR40_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HAQ4361067.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            4891..5523
                     /locus_tag="IXR40_001207"
     CDS             4891..5523
                     /locus_tag="IXR40_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361068.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(5657..5782)
                     /locus_tag="IXR40_001208"
     CDS             complement(5657..5782)
                     /locus_tag="IXR40_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4361069.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(5916..6809)
                     /locus_tag="IXR40_001209"
     CDS             complement(5916..6809)
                     /locus_tag="IXR40_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HAQ4361070.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            complement(6991..7917)
                     /locus_tag="IXR40_001210"
     CDS             complement(6991..7917)
                     /locus_tag="IXR40_001210"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HAQ4361071.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            complement(8002..8763)
                     /gene="pflA"
                     /locus_tag="IXR40_001211"
     CDS             complement(8002..8763)
                     /gene="pflA"
                     /locus_tag="IXR40_001211"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HAQ4361072.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            complement(9007..11238)
                     /gene="pflB"
                     /locus_tag="IXR40_001212"
     CDS             complement(9007..11238)
                     /gene="pflB"
                     /locus_tag="IXR40_001212"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HAQ4361073.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            complement(11515..13965)
                     /gene="parC"
                     /locus_tag="IXR40_001213"
     CDS             complement(11515..13965)
                     /gene="parC"
                     /locus_tag="IXR40_001213"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HAQ4361074.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDISIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            complement(13977..16022)
                     /gene="parE"
                     /locus_tag="IXR40_001214"
     CDS             complement(13977..16022)
                     /gene="parE"
                     /locus_tag="IXR40_001214"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HAQ4361075.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            complement(16188..16622)
                     /locus_tag="IXR40_001215"
     CDS             complement(16188..16622)
                     /locus_tag="IXR40_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HAQ4361076.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            16749..17387
                     /gene="plsY"
                     /locus_tag="IXR40_001216"
     CDS             16749..17387
                     /gene="plsY"
                     /locus_tag="IXR40_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HAQ4361077.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            complement(17519..18394)
                     /locus_tag="IXR40_001217"
     CDS             complement(17519..18394)
                     /locus_tag="IXR40_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HAQ4361078.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(18476..19267)
                     /gene="codY"
                     /locus_tag="IXR40_001218"
     CDS             complement(18476..19267)
                     /gene="codY"
                     /locus_tag="IXR40_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HAQ4361079.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            complement(19285..20685)
                     /gene="hslU"
                     /locus_tag="IXR40_001219"
     CDS             complement(19285..20685)
                     /gene="hslU"
                     /locus_tag="IXR40_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HAQ4361080.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            complement(20699..21247)
                     /gene="hslV"
                     /locus_tag="IXR40_001220"
     CDS             complement(20699..21247)
                     /gene="hslV"
                     /locus_tag="IXR40_001220"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase proteolytic subunit"
                     /protein_id="HAQ4361081.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            complement(21284..22189)
                     /gene="xerC"
                     /locus_tag="IXR40_001221"
     CDS             complement(21284..22189)
                     /gene="xerC"
                     /locus_tag="IXR40_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HAQ4361082.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            complement(22387..23763)
                     /gene="trmFO"
                     /locus_tag="IXR40_001222"
     CDS             complement(22387..23763)
                     /gene="trmFO"
                     /locus_tag="IXR40_001222"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HAQ4361083.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            complement(23732..25810)
                     /gene="topA"
                     /locus_tag="IXR40_001223"
     CDS             complement(23732..25810)
                     /gene="topA"
                     /locus_tag="IXR40_001223"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HAQ4361084.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            complement(25932..26789)
                     /gene="dprA"
                     /locus_tag="IXR40_001224"
     CDS             complement(25932..26789)
                     /gene="dprA"
                     /locus_tag="IXR40_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HAQ4361085.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            complement(26845..27612)
                     /locus_tag="IXR40_001225"
     CDS             complement(26845..27612)
                     /locus_tag="IXR40_001225"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HAQ4361086.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            complement(27605..28465)
                     /gene="ylqF"
                     /locus_tag="IXR40_001226"
     CDS             complement(27605..28465)
                     /gene="ylqF"
                     /locus_tag="IXR40_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HAQ4361087.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
BASE COUNT         7685 a         6102 c         4941 g        10113 t
ORIGIN      
        1 gaaatgaaaa aattaaattt atttacagaa ttgtgcggaa tcattttagg cgcaggaatc
       61 tacggattag ctgtgacagg aatcaatatt ccatctaagc tggcagatgg tggggttact
      121 ggtattgctt tgcttttgca taatcttttt ggattcgctc cttctgtcac ttcactgctt
      181 tttaatttac ctttattgct tatctcattg tttctttttg gaaaacacgc ttttctccgg
      241 acgatcgtcg gaacatttgc gctagttttc tttttacatt tatgggagag ccttcatata
      301 cattttgctg tagatagtct actgatcaat agtttgatga caggtattct ttctggcatt
      361 ggttgcggtc tcgtctttcg attcggcgga agcacaggcg gaacagatat catttatcaa
      421 gccattgaaa aatattttca tattaagatt ggcaaaagtc ttttcttgat tacttttggt
      481 attttagttg tctccttgct ttatttggat ctcacacatt ttctgtatac attacttagc
      541 tgttctattc tatcttatac attgaataaa gtgaagtatc tggaaattgg atctgttttg
      601 ccccaattgg aagcaaaaca gactacagaa acatttgaac cacttgatcc tcttgaacag
      661 ttagagcact gattcttatt tttcactact ttatttaatt tacagaaata tcattatgta
      721 aactaaaatg atattattca gtaaaatctt ctttataaaa aaataaacta tttttgcaaa
      781 cgatctgcga aaatagtttg tttttttatt ttgccattat tttcttactt attgggagaa
      841 aaaattcgct taaactcaaa aaaatttgag gatacgatat aaactttcgg atagagtata
      901 aaataaggaa acgccgcagc gtttcctttc caactgtagc cgaatataaa tttgtatatc
      961 acttatttaa aatagctatt ttctcccaaa gagtttcctt gatcatcgat caatccttgt
     1021 aatgagcgtt ctaagatacc atggcttttt ttcgattttt tttcttctga ctgctttgtt
     1081 tcctctaacg tttttgttcg attgaatgtt cgtacagacg gctcaccatt tcttttttct
     1141 tgatacggcg tcggttctgt atcgaacaac agataagagt catccgtttt tttcatcgat
     1201 tcgattaaat gatcctcaga aattttgctt tctctagggt ctgggataat cgatgcgggt
     1261 acatatttag gaacaaaata agaacgctcc cgcaccttcg tgtcaacaga tgcgtttcgt
     1321 gtagtatgct tggactctgt ccttgtttca ctttgtctga cagaacgaga ggaatcacca
     1381 aaaagttttt ttcgtcctgt cgatgtgatt tctgattggt aatggccggt ataatccggt
     1441 aattttcctt tatgcttttc caaattttcc ttacgcggag ctgacttcaa tccatttgtt
     1501 gcacgacgct tgcgacggat tttctcggtg ttcgtgttcg tgaaatgaaa ttctttcatc
     1561 tgttcaaacg gggactgatt ctgttcagtc aaaagatctt cttgtccgtc aaataatact
     1621 cgcttcttgt cgttggttaa ttttacgcct aactcatcat cgtacgcagg aaaacggaaa
     1681 tgttttcgtc tgatttcttt cattcaaacc atccttctca aaaatggaac ttttctcaat
     1741 aatagcacag attcattgtt ttcagtagca atgcgctgat tattttaaga aaatagcgat
     1801 gaatttcata aatatatata tagtaataag acttaattcg ttgtctctct gataactagt
     1861 tcaggaaaaa aacgacgata accttgactc gccccttttt cttctatttt ttttaacaac
     1921 atttctccac atacttcacc catacgtata atatcttgct tgatcgttgt caatttaggt
     1981 gaactgattt ggtctaaaaa taccccatca aatccaatca caccaaattc ttcgggcaag
     2041 tgtcctccag catttataat ccctcttact gctcctagtg ctagccgatc tgaactacat
     2101 acaaaacaag ttttatctgt aaaatctgcc cagttttctg tcatatatct ttctacttct
     2161 gtcgaatgat ttggaaaccg caagatttta ctaggaagat caacttcctt catcacagat
     2221 aaataaccag tttcccttga aatttcaaaa ggctcgtcca cttcgatacc gatataaata
     2281 atcgtttgat aatctctttc taaggcatat tgcgttgctt ttgctgtacc atattcatta
     2341 tcgctgtcta cataatcata tccttcagaa ttttccccaa acaagacaac tggtttttcc
     2401 aaacggtcga tccaatcgaa gtcttttttt ctgacacctg tgatgatgta tccatcacaa
     2461 gaaccgacgt cgaaggcatc atttgtaact aattggagag aataatgcgc tttaccgatc
     2521 cgtttagcga ttcccatcag caaattcatg taatagggct cagttgtgtc gatttcttcc
     2581 agtataaata atttgatgat ctgcgaccga ttcgtgacaa gtgcttttgc agcaatattt
     2641 ggacggtaat ccagttcagc cattgctgat aaaactaact ctttcaattc gtcagtcacc
     2701 tgttccggat gattgatgac tcgagagacc gtcatttttg aaacattggc acgttttgca
     2761 acatctgcta aagtgggcat gctctcttcc tttctaacat gttgtcattc ttactatcaa
     2821 ttataccaaa ttttcctaac agagtttatt atagcccaaa ataaaaaacg gaaaatcctc
     2881 tatcgtcatg agtgattttc cgtttcaatt atttatactt ttttatcaaa ttttttgcta
     2941 aaaaagtgga agcttcttcc attagtggta tttgtaccat atgtcgctgt gtttttgagg
     3001 aacgaaaaac aatttctttt ccgtaagact tatgccgatt tttttctaca aatcgttccg
     3061 tttgtatata agggattttt tcgtcagctt gtccatgcca aaagaacaga ggacgtccag
     3121 ctaacttttc cggctgcaat gacaaatcat agctcttaac ccatgaaatc aaatcaaaat
     3181 agtcttttgg tacgacataa ttatattccg atgcgcgcct tacgatttct tttccatatt
     3241 ccaaaggtgc aggggaaccc atcaaacaca cgcccgctac tatatgagga tgtttagcca
     3301 acaaggcgca tgttgtcatt ccccccatcg aaaccccgcc aactgcaagc tgatcatgta
     3361 gaagacctct tttttctaaa tgcttgataa gtgtgtcaaa ttcaaacaga tttccgtaga
     3421 tactatccca aaatgtatag gatggaatag aagaaaccgg ctgtttgcgc tccccatgat
     3481 tcatcgcatc tggcaggatc acacgaatgc cctgctgcgc aatttttctt ccttgcgtca
     3541 aaactaactc cttacttgtc tgccatccgt gataatagat gacaacggga atacgttcct
     3601 ctcttaattc tttcagaaca acttctaaca ctggaatatg atggacagaa cgtttcaata
     3661 taattggatt caattgttac tcacctattt tcattaaatt tcctgatcgc catagcaacc
     3721 atgctccaac agttgtctgg aacaggttca gtgtaccaaa taatataaat gcaggactga
     3781 atggctcggg aaataagcac agagaacaaa gtcccaccac tcctaatgct agcgaaagga
     3841 gtggataaat agaaaaattc aaaaaactgg caacgctacc gaaaatatta ccaataaaca
     3901 gtatcaaaaa gaaaaaaacg cttaaaatta aaccatctgt cagcgacatc tgaaaaacaa
     3961 tgttctctac ctcaattggc tgttgaatcg aatagacacc taagtatata ctgagaagga
     4021 gacttagcac gtggctggca caaaacacac gattgaccgt tttcatttta atcacctaac
     4081 ctatctttat aattctatta taatcatttt atcatttttt tgtatgtata aagtttcaat
     4141 ttttcttcac ttacgatttt ttttgatatt gttgttatat aaatgaaagg agttttacaa
     4201 atgattgatc caaaaatgtt ggggatgatc ttcctcatta attttgctta tatcactctg
     4261 aacacgttac gtttcatgtt gacaatgaaa ggctatcgac tgattgctcc acttgtcagt
     4321 atggtcgaga tcacgattta tatcgtcggc ttatcccttg ttttagatcg tttagataat
     4381 ccactgaatt tatttgtcta tgcgttaggt tacgcagtag gtatcagtgt cggaattttg
     4441 attgaagaca aattggcatt aggatacatc atggtcacaa cgattttgcc agcaaatagc
     4501 gcagaagata aaagtttgcc gggtatactg agagaacacg gttatggtgt gacacagact
     4561 tctgcaatgg ggctggaagg tgagcggcta gttctcgaaa tactttctcc tagaaaaagc
     4621 gaacgtgaac tgtatcgcct gatcaaagaa atcgaagagc gtgcttttat catttcttat
     4681 gagccaaaat atatttcagg tggtttctgg actaaaaaag tgagaaaacg acaaggaaaa
     4741 taactcacaa acttaaaaac tgtctaatat ctaaattaaa ttttaaatgt tagacagttt
     4801 ttatttatta ttttgattaa aaaacatcga catatactca tcaatttgtt attatacttt
     4861 atatacttat caatttaatt tggagatatt atggaaattc aacgtagaac cactaatttt
     4921 ttacatttag gctctttttt tgcaactttg acgatcttat tttttctatg ttattcatac
     4981 cttaagacct cacatgcgcc ttctagtgca ttaggctggt tgcttttgga tcattctgat
     5041 atcacagaag ccgaagaaaa tccgtttttt ttgattttgt cttctctttg cggcttactg
     5101 ttttctgttt atttcggtgc ctattttttt catcgacatc ctggtacgtt aaacgaagct
     5161 tcaagcgtat tgattgcatt taaaacgttt tcttttttag caattctttt ttattcgttt
     5221 aatcacaata cgcttttctt ctttatcatg aatggtttag tcgtgatttt atccattttt
     5281 acttatttta ttttttcact catttttagc caattgaaat gtccgctctt ctttcgatta
     5341 gttcctgtca cctgttttat ttacagcttg ttttcctttt ttgtccttgc tttaatgcca
     5401 ctgaccaacc cttcgacgat ccaagtcgca ggaaatctgt tggatatgct cttcatcgtc
     5461 agtctaggtg tatttatgtg gcaaagaaaa aacaaacaaa ataaaaagca ttttgaagcc
     5521 tgactattac gacttcataa atgctttttt agttttaaac acttcaatct aaaagaataa
     5581 cccaagattg gataaattat taatgactcg ccattcgttt cttagtgatt ctggattatc
     5641 aaatggactt cctaatctaa tcagctagtt cttcccataa aatgccatac ttgactgaat
     5701 cataatattg attatttaaa aatctaactt ttcttatcac tacttccttt gtcattccac
     5761 atttctcacc atttttttgc attcctttgt ttccagacca tgtagtgaat ctaataggtg
     5821 gtagataggc aaaatactca aataattctt ttaaccataa aggaagagaa aggctcctcc
     5881 tgcaagagtc agtataattt ttgcttactg ctctcttagg ttttactcac taaaactgtt
     5941 ccatattctt tgatataaga aaatgcatgc ggtataaatt tcttgctcag ctcagaaaag
     6001 atttgtcgtt taagaaaggc catttcctcc attgtcaatg aaggatccaa tgttggtaat
     6061 tcaatctcaa aattgttttt ttcgacaata ggtaattcta atgtgaatga ttcttcttcc
     6121 tttatagtat tcgtcacaag tagagactga tggaaaatac taggccggcg atttttatat
     6181 ttattcttac gtatcctgtc aacgataact tctatttgat caaaaaagta cgattcattt
     6241 acgtctccaa taagttcggc taattctttg aatgccttcg ttacaggaag ctgattcttc
     6301 tgtacaaaaa agtaattagc caaagtaagc gggaagtgtt ctatagagga aagtgtgata
     6361 aaacggtact tctcatttcc tgcagttgtc ctcagcaatt ctgtctctcg gctgtttctt
     6421 actccataaa aatacgcttc tttccgttca tcttcgaaac aatacgccca aataacttct
     6481 cccatcgcta atttttgttc atcaacagag agtctcttca attgttcagc tatggtttca
     6541 gcagccgaag tggcttgttg caagtaatct ttaggatcaa atattggaaa gttcaaatga
     6601 tatcttcgtt cttccctctt gattaatcct gcatcgatca ataaatcaag aaaatgggaa
     6661 aatttatttt gcgaaaattc ttttttcaat tctcttagaa tcgtttcttg ttctcgatgt
     6721 tcatatagat aatcggtcaa tgaagaaaaa agcggatcat cggtcagttt ttgataaaag
     6781 ttttccttat tttttgaata atagttcata tatgttctct tttctatccg ttttatttta
     6841 cttaaaaggc ttttacgtaa aaaggaggaa gaacaagagt cataattgac tgttattctc
     6901 ctccatttct tcggccttta gtatgttcta tgtttctttt tatatcaatc gcttatccat
     6961 tcattttgaa tgcttcatac taccatttga ttagctaaat acagccgtca attgaggtac
     7021 gacttgtttt ttacgtgaaa cgacaccttt aagcaaagca cggttgttgg tcaaagttgt
     7081 ttggaaagct tcttctactt tttcttttcc tttaccagca acaagtaatt ctgaatcact
     7141 gtctaagatg tttgtgacaa ctaatacgaa cagatcgtag ccatttgctt tcatttcatc
     7201 ttccattgct gcttctagct ctgcttgtcg atccatcact tcattaaggt ccactgtatt
     7261 gacttgagcg atacgaacgt tggaactgcc cattgggaaa ctttttgcat ccaaatcaag
     7321 aagaaccgca gctgatttat cacttagatt tgttcctgct ttcaacattt caagtccata
     7381 agtgtttaga tcgacttcag cgattgctgc aagttctttt gcagctgctt catcttcagg
     7441 cgtacatgtt ggtgatttga acaacaatgt atctgaaatg atagctgaga gcatgattcc
     7501 tgcgatttct ttaggaattg ttacttggtt ttctttatat agttttaaaa taatcgtact
     7561 tgtacatcca actggttctg cacgatagta caatggatta gctgtttcaa agtttgcaat
     7621 acgatggtgg tctactacag ctaaaatatt tacttcgctg atatctgaaa tactttgttg
     7681 gaattcatta tgatccacaa gcatgacatc tgcattttct gctttagctg actctactac
     7741 tcgtggtgca gatagctgaa agtggtctaa tgcgtattgt gtttcttcat taggtgtacc
     7801 tagagcaact gcttctgttt ctttacctaa ttcattttgc aagtgtgaaa acgcaatggc
     7861 tgccccgatt gcatctgtat ctggattttg gtgaccaaaa actaaaattt ttgacatgtc
     7921 attcgctcct ttgtgatttc tcctatttaa taatagcaaa aaaacggaaa gaagcaatac
     7981 ttatcttctt tccgatgcga cctatcgcgt taaatatttt gtatactctt ctgtatgaag
     8041 caatcgttta gcattttcga cacgttcttt tgtaggtggt tcgatccctt ctaatggata
     8101 tttcaaacca agtgtttccc acttgtattt tcccatcgta tgataaggaa gaatctctac
     8161 tctgtctaca tttgacaagg tttgaataaa gttgtctagt cggatcaaat attcatcata
     8221 atcacttcgc tcaggaacta gtacatggcg aatccaaacc ggtttgttga tttttgacaa
     8281 atattgagcc atttctaaaa tattttcatt gtcccaatgc gttagttttt tatgctcttc
     8341 attatcgatg tgtttgatgt caaataacag taaatctgta tacttcatca attcttgaaa
     8401 acgtgaaaag aaaggttctt catacgtaaa aggttttccg catgtatcca atgtagtatg
     8461 catcttccgc tcttttgctt ttttaaatag ttcgatcaaa aaatcgatct gcaatagagg
     8521 ttctccacca ctaacagtaa taccaccttt atctccccag taaggtctga agcgttctgc
     8581 tttatctaaa agttcatctg ctgtgtattc tttccctccg ccaatattcc aagtatctgg
     8641 attgtgacaa aattggcaac gcatgcggca tccttgcata aacacgacaa agcgcagtcc
     8701 aggtccgtct actgaaccga aagtttcgat agaatgaaca tagccgattg ttttttcttc
     8761 catttaagtt cacatctttt ctttgatttc attttaagta caagttagct gtcgaagcga
     8821 agctttctga acaaaatttt tcgcaattgc cgcttcgtta tgtgtaaaat ttacagggac
     8881 ggaacataca agtcctgccc ctgtaaatcg tttctttcaa ataagcatac tgattattcg
     8941 attttgatgc gatggctatt caacgtcctt tcgacgctaa gtcgaaaaac ttttttcacg
     9001 aactttttac attctgtcgt gtgaagttct catcaagaca tctaattgtt gttctcttgt
     9061 caagtcacgg aatttaactg cataaccaga tacccggatc gtcaagttcg gatatttcat
     9121 tggattttcc attgcatcac gcaataaatc attactgaat acattgacat tcaaatgata
     9181 agctcctttt gagaagtatc catctaagac attacgcaag ttttcgattc ttgtatcttg
     9241 ttcttttcca agacctgaag gattgattgt ttgggtattt gaaattccat ccaatgcaca
     9301 gccgtaattc attttagctg ttgagttcag gctagctaat aacccacttt gttccgcatt
     9361 gtaacttgga tttgctcctg gcgcaagtgg ttttccagct tcacggccat caggagtatt
     9421 tcctgtattt ttaccgtaaa caacatttga agtaatcgtc aataatgaag ttgttggttt
     9481 tgagttgcgg taagttttat gacgtttgat ttgtcccatg aagtattcca agatccatga
     9541 aactaattca tctgcacggt catcatcatt tccgtattta gggaagtcgc catccacttc
     9601 aaaatcaact gctattcctt tttcattacg gattgctttt acttttgcat atttgatcgc
     9661 tgacaagctg tctgccgcat gagagatccc agcaatacct gtagcaaatg tgcgttgcaa
     9721 gtcagaatcc atcaaagcca gctgagctgc ttcataagaa tatttatcat gcatataatg
     9781 aatgatgttc aacgtattga catatagttc tgctaaccaa tccatcatat tcatgaagtt
     9841 atgtttcact tcttcaaagt ctagtatttc tgatgtgatt ggacgatatt ctggtccaac
     9901 ttgggcgcca gtcacttcat cgactccgcc attgatggca tataatagtg ttttagccaa
     9961 gttagcacga gcgccaaaga attgcatgtc ttttccgaca actgttcctg atacacagca
    10021 agcaatcgca caatcatcag aaccccattg ttcacgaagc tgattatcat tttcgaattg
    10081 aatcgaagaa ctttcgatag cgattctgct agcatatgtt ctgaatcctt ctggaaggtg
    10141 ttcagaatac aaaacagtca agtttggttc tggtgaaggt cccatatttg ttaatgtatg
    10201 aagcagacgg aaatcattct ttgtaactaa tgaacgacca tctaatccca tacctgcaat
    10261 ggataaagta gcccagatag ggaatcctga gaataattgg ttatattcag gtgtacgcgc
    10321 gaatttgacc atacgtaatt tcattactaa gtggtcgatc aattcttgtg cttctttttc
    10381 tgtgattact ccattatcca aatcacgttg gatatagata tcaaggaatg ctgagatacg
    10441 tccgattgac atcgcagcac cattttgtga tttgattgct gctaaatatc cgaagtatag
    10501 ccattggaca gcttcttttg catttgcagc tggtttagaa atatcatagc catatttcgc
    10561 agccatttct ttcatttgcg ctaatgcacg atattgttca gtgatttctt cacgtaaacg
    10621 aatcacttct tcactcattg tatgataacc agtcatatca tgatcttttt tcttttgttc
    10681 catcaaatag tcgattccat acaatgccac acgacgatag tcaccgatga tacgtccgcg
    10741 accgtaagcg tctggaagcc ctgtaatgat tttgttttta cgagcagcac gcatttcagc
    10801 agtataagcg tcaaatacac cttgattatg tgttttgcgc cagtcagtga aaatatgtgt
    10861 caattcatcg tttggtgtat agccattgct ttttagcgca ttgttagcca tattgattcc
    10921 gccgaacggc atgaatgctt gtttcaaagg tttgtctgtc tgtagaccga cgattttttc
    10981 caaatcttta tccaaatagc ctgcatcgtg tgaagtaata gttgatacga tttctgtgtc
    11041 catatcatag acaccgttac gctcgaattg gatatcattt aacttttgca attcatccca
    11101 taatttttct gttgcttctg ttgggccttc caaaaagctg tcatcaccgc gatattcagt
    11161 gtagttattt tgaataaagt ctctagtgtc tacgccttct ttccatttgg tacctttaaa
    11221 tccattccat tgctccattg tatggacctc ctaaatttct gttttatgta acagttttta
    11281 cgtgattagt ataacacagc accctatctt tgcaagggtt ttcttgtttt ttatttaaca
    11341 atttttatgt tttatttaca tatatttaaa tcaacgttga cataccaaca tttaagcatt
    11401 gtgaacactt tcatcttttt ttgcaaacgt ataaggattt attaaaaatg aatgaaaaag
    11461 agacgccacc tgtattaata cagatggcgt ctcttcatta aaatactaca acagttacga
    11521 ctcgatgaaa atctcaggag catcgataac ttcgatgact tctccacctt ttttctcatc
    11581 catcgcaaat gatccattcg atgttcgatc acctataggg aaatcagttg ggtcaatcgt
    11641 taactgctgc cctttttgat tcatcaaggt tatttctttt gatcttcctt ccgacatata
    11701 gataatacgg tgcggatttt ttttcagctc acgcatgacc gtcactcccc gcttcgcacg
    11761 tgaagtttgg ctgatttctt gagcaagcat gcgtttaaca gctcctcgct gagtaacgat
    11821 tacgatcggc gtatcacctt ctgctaacac aagcagcccg ttgataatcc tatctccatc
    11881 tttcaaattc atagacttca ctccagctgc ctttgctcca acaacgggaa catctgttaa
    11941 aggatagcgc aaacccattc cttgatgcgt tactaagaaa acatctaagc ctggctgatc
    12001 ttctttcaga tacacagcaa tcagttcatc ttcttccgcc tttagcttca tacagctgag
    12061 cggacggctc ttataggtgc gccatggttc gaactctgtc attcgtgttt gcttgatcaa
    12121 tccattcttg ctgatgaata caaatgtttt ctctgcttga attttttgat atgggaaaac
    12181 agctaaaatc gattcgtcta cagacagatt ggagattgtt tgagaaatgt gctcaccagc
    12241 atctttccat ttcaaatcgg gtagttcatg gacagggcgg tagatcacat ttgctttatt
    12301 tgtgatcaga agaacatggt ccaatgtact caattcacct gagtatagca agtagtcgcc
    12361 ttctcgcatc ccgatttctt ctggtttgga agcactataa gaacgaaggc ttgttcgctt
    12421 cacatagcct tctcgcgtca cactgacaat tacgtcttct tgtgccacta agacttgcgt
    12481 atcaattttg atttcttcga tttcgtcttc gattgtcgtt agacgagcgg aagaataatt
    12541 ttttttcact tctcgcaatt cttttttcat aacagagaaa agctctttgt catttgaaag
    12601 gattttattc aactctgtga tttgcgcaat caagctttcg gattcctttt gaagctctgt
    12661 gatatccgtg ttcgtcaaac ggtataattg caatgtgaca attgcttctg cttgttcttc
    12721 tgtaaattga aagacgtcga ctaaattctt tttggcgtct tttttgtctt tactttcacg
    12781 aatcgttgcg attacttcat ccagaatcga taaagctttc atcaatcctt ctacgatatg
    12841 ctgtcttttt tgagctttgg ctaaatcgaa ttgactacgt tttgttatga cttgctttcg
    12901 atgctcgata taacttctta aaatgtcttt cagtccaact tgatgcggag tcatatggtc
    12961 gatagcgacc atattgaaat tgtaattgat ctgtagctca gtgtttttga acaaataatt
    13021 caaaattcct tgagcattgg cgtctttttt caattcgacg acaatttgca gacctgttct
    13081 atcactttca tctcgtactt cagctattcc atcgattttc ttattcaaac ggatctcatc
    13141 catttttttc accaaggtcg ctttatttac ttcatatggg atttctgtga tcacgatttg
    13201 ctgtttatta cccttcattg cctctatctt tgttttcgaa cgaagaataa cttttcctcg
    13261 tcctgtttca taagcttttt tgatttcatc ttttccttgc aagatccctc ctgttggaaa
    13321 gtcaggtcca ggaatatatt ccatcaattt ttcaaggctc gcttgtggat gatcgatcat
    13381 atagattgtg ccatcgatca cttcagctaa gttatgagtc gggatttctg ttgcatatcc
    13441 agcagatata cctgtcgatc cattgacgag aaggtttggg tatcgagctg gaaggactgt
    13501 tggttctttt tctgtatcat caaaattcca cacgagatcg actgtttctt tctcgatatc
    13561 tgctagcatc tctccactta acttggataa tctggcttca gtataacgca tcgcagcagg
    13621 tggatcaccg tccatactcc cgttattccc gtgcatttcg atcagtactt cccgcaactt
    13681 ccagtcttgg ctcatgcgga ccatcgcttc ataaatactg atgtcaccat gaggatgata
    13741 attccccatg atatttccga cagattttgc tgatttacgg aatcctttgt catacgtatt
    13801 gccatctttg ttcatggcaa ataatatccg gcgttgcact ggcttcaatc catcacggat
    13861 atcaggcagt gcacgttctt ggataatata tttggaataa cgtccgaagc ggtcacccat
    13921 cacttcttct aaagttaatt cttgtacttc ttgtcgattt tccatcaggt gacctcctat
    13981 tctacttcaa ataactgatt gttttcattt ttatctgctc gttcttcatc taataaatca
    14041 ttagaaactg aaggagagat ttcagtatcc tcttttttat ctaagatact gccatcttct
    14101 tcgagcgtaa attgcacgtg attttcgatc cattttcttc gaggttctac tttgtcaccc
    14161 atcagtgtgg ttactcgacg ttcagcttgc gcagcatcat cgatacggac gcggatcaac
    14221 gtacgggaag tcggatccat cgttgtttcc cacaattgtt ccgcattcat ctctccaagt
    14281 cctttatatc gctgcagcat atatcctttg ccgacttttt taatcattgc tgccaattcg
    14341 tcatctgtcc acgcatattc aatgacttgc ttctttcctt gtcctttgga tactttatat
    14401 aaaggcggta acgcgatata tactttccca gcttcaatca gcggtttcat ataacgataa
    14461 aagaaagtaa gcagtaatac ttgaatatgg gcgccgtctg tatccgcatc ggtcatgatg
    14521 attactttgt cgtaattaca gtcttcgata gaaaactcag gaccgactcc tgcaccaatc
    14581 gtatagatca tcgtattgat ttcttcattt ttcaagatat cttgcatttt agctttttcg
    14641 gtattgatga cttttcctcg taaaggtaga attgcttgga actttctgtc tcttccttgt
    14701 ttagcagatc cgccagcaga atccccttcg actaaataca attcattttt cttagggttt
    14761 cgggattgtg cgggtgtcaa ttttcctgaa agaagagatt cgcctttttt acgcttcttc
    14821 ccatttcggc tttcttctct ggctttacgt gctgcttctc tcgcttctct ggctttgatt
    14881 gctttacgga ccaacatctg gctcatttcg ctattttcct gcaaataaaa gcccatttgt
    14941 tcactgatga cgttatctac tacggtacga gcaactggcg taccaagttt ttcttttgtt
    15001 tgcccttcaa attgcagaag attttcaggt acacggatag aaagtacagc agctaaccct
    15061 tctctgaaat cactaccttc cagattcttg tcccgttctt tcagcaaacc aacttttctc
    15121 gcatattcat tataagattt cgtcatcgcc gctttcatac cagcttcatg ggttccccca
    15181 tcttttgtcc gaacgttatt gacaaaagat aaaacatttt ctgaataacc gtcattgtat
    15241 tgataagcga cctctacttc gataccttct ttttctcctg aaaaataaac aactggtgtc
    15301 aatgtatctt tttcttcatt cagataatca acaaattctt tgattccttc ttcgtaatga
    15361 aaaatttcct tgactggttc ttctccacga agatcagaaa gagagatttt aacgcctttt
    15421 agaagaaagg cagattctct taaccgttcg gctaaaattt catatgaaaa tttcgttgta
    15481 ctgaatattg tatcatctgg taaaaaatgg acagtcgtcc cgtttgcttt ttttgttttt
    15541 cctatctttt tcaaagtacc gtcaggttta ccgccgtttt taaatttctg ctgatactct
    15601 acgccatctc taacgatcgt tacaattagc catttcgata aggcatttac cacactggct
    15661 cctacaccgt gcagtccacc agaagttttg taccctcctt gaccaaactt tccgccagca
    15721 tgcagcacag taaaaatcac ttcaactgtt ggtattccgg aagcatgcat tcctacaggc
    15781 atcccacgtc cgctatctgc aacagttata ctattgtctt catggatggt cacatcaatc
    15841 tcactgccat aacctgataa tgcttcgtca actgcattat cgacgatttc atagactaaa
    15901 tgatgcaagc ctcggctgtc agtggatcca atgtacatcc ctggtctttt tctaactgcc
    15961 tctaatcctt ccaatacttg gatggacgag tcattgtatt cgttgtttac tttttttgcc
    16021 aaggcaaacg ctccttcaat aatactttgc ggcaaaaccg caccacgatt atcatactag
    16081 aaaaggtcgt gaaaaaaaag agggtagacg agaaatcaat tttaattatc tcctaaccgc
    16141 tttttcgaca ttcccctcta tcgatcatct cttctttgtg gtcattttta tttttggttt
    16201 tctttcaact taccaagttc aatcttaata caacgatcca ttacgatatc tgtacgtcct
    16261 gcttttctta gcatctcagc tgcttctttg ttttcaatcc ctaattgtgc ccagaacact
    16321 ttagcatcag ttttcaaaaa atcacctgct atttcaggta aaaattcact ccgtctaaat
    16381 acatctacga tatcgattgg atcatcgatt tctgtcaaat tcgcatagac tttctcgcct
    16441 agaatttctt caccagccaa taatggattt actggtatga ttttatatcc attgtcttgc
    16501 aatacctgtg caaccatgta acttgttcgt tctggtttat tgctcaagcc tacgacggca
    16561 atattttttg cttcttccaa atagttgaaa atcgtttctt gtgttggatt ttttacagac
    16621 atttctgcca ccccttgctt ttctttttat tccatctatt atacttgtat ctttcatttt
    16681 ttcaattgtt cctgttacct attcatgcta aaataaagga tagttttcaa cttgaaagag
    16741 ggtaaaaaat gaaattgatc ttattactta ttttagcata tcttttaggt tctattcctt
    16801 ccggtgtctg gattggcaaa ttgtttttca aaaaagatat ccgacaacac gggagcggta
    16861 atactggaac gaccaataca tttcgtgtat taggcaaaac agccgggatt gttgtcctgc
    16921 ttatggatat tttaaaaggt acattggcta cttgtttgcc gatgatcttc cacctttctg
    16981 ggattaaccc tctttggttt ggggtatgcg ccattcttgg ccatacattt ccgatttttg
    17041 ctgggttcaa aggaggaaaa gctgttgcga caagtgcagg aatgctttta ggatttaatc
    17101 ctgtattttt tgtttattct tgtatcatct ttatcgttag tttattttgt acaagtatgg
    17161 tgagtttgag cagtatgatc agtgcagtat tgatcacttt atctacgatc gtccttcctt
    17221 atgtagctcc tgtgattttg gctaagccca attggttact gacgatcatt gcctttttag
    17281 tttcttcctt tatcttttat cggcataaag acaatatcaa gcgtatcaga aaccatactg
    17341 aaagtcgaat cccgtttggt ttgaatagca gcaagaaaaa atcctgatac tttttcattc
    17401 caaagagata aaacgggagt gtgacaaatc gatgtcacac tcccttatta cttacaggat
    17461 agctttttta cacaccttgg taaacggtgt tccctgctaa cttctcggtc acaacctctt
    17521 acttcactgt gatggaatat tttgtcttga agatttcatg ggcacctagt tgattgatcc
    17581 ctactttttc catcaagttt ccactactgt tcaccgtgtc agcgattccg caccacggtt
    17641 cgatacaaac gaaaggcgct tcttttggat aaggagacca gatccctaca taaggcatat
    17701 ctttatagct taaagttacg ctatgggaag atttttcact tcgaatggcg tacgcattta
    17761 gaccccttgt ttcaaaaacc aaggcatctt gctcaaaaag ttcacgattc aaagccagat
    17821 tcgtatttgt ctgacctaac gtcttttgat ccatatcgat gaatgggcct ttcaatggta
    17881 ggcgtaatct tgatttcaat ggagaaaatg ccagatagaa atcttcaaat gacaatcctt
    17941 cttcaagagg tacattgaaa gcaggatgtc caccgataga aaagaacatt tctttttcac
    18001 cggtatttgc cacttgataa tgaaccgtga tgccgtctcc tcctaattca tagctgatca
    18061 ctaattcaaa atcaaatgga tacttttcta atgtctccgg cgtactcctt aagatgaaac
    18121 tagccatttc ttgtccatgt tcaatgactt caaaatccat atcccgagca aatccgtgtt
    18181 gccccatttg atatgttttc ccttgataaa catactgatc atcttttaaa cgtccaacaa
    18241 aagggaataa aaccggtgca tgtctgcccc aatacgctgg atcaccttgc cagatatact
    18301 ctaaaccatg ttcttttgat ttcagactga tcaattccgc accgtgttca gcgatttcgg
    18361 cgatcagctg gtcattttga ataataacag tcattgccat tcctccaact tcgacttact
    18421 ttttaaaatg ggaaggctgg aacaaacatt tctatctgcc ccagtcccct tacttctaat
    18481 aactgtgttt tgctaactcg tctttaaaac gggaattcaa tacttttaaa taagttccct
    18541 tcatgcctaa cgaacgagat tcaatgattc cagctgattc caattttcgt aaagcattga
    18601 cgatcacaga acgagtgatg ccgatactat cggcaatatt agaagcagtc agacgacctt
    18661 catctccatc caatgcttca aagatagctt gtacagcctt caattcgcta taagataatg
    18721 tgttgattgc catttggaca gccgttgcac tccgtacatc tgcttcgatg cttcgagact
    18781 tctgataaag gatctgcata ccgacaaccg tagctccata ttctgctaag actagatcgt
    18841 catctgcaaa cgattgttcc atacgagata agataatcgt acccaaacgt tcgccagctc
    18901 caaagatcgg aacgacagtc gtcagaccaa atggatattt ctctcttgac tctaccggaa
    18961 atgcagtaat atcactagta attgggatat tagcttcagt tttcatcaac tgtgccactg
    19021 tatcagtata agattcagga aattgtttct caacaaacat tgttttgatt cgttcattgt
    19081 tcacatcgtg acgttcatta taacctagta atactccgtc acttcctatg atataggtgt
    19141 tgctgtcaag aataccacct agtgtgacag ccattttatc gtaaggcaaa tctgcttgca
    19201 tgtcaaaagt attcttttgc tgcaaaagtg tgtttatctt gcgggttttc gttagcaagt
    19261 ctgtcattgt cgtcctccga ttttttataa aatatagcga cttaaatctt catttgccgc
    19321 aattgagcca agtttgtcat ccacatatgc ttctgtgatc gttatttctc ccatttgcat
    19381 atctggtgct tcaaataata gatcttctag tagtttttcc aaaatggtat gcagtctgcg
    19441 tgcgccgata ttatctgtgt cacggttgac atcgaaagcg atttgagcga tccgttcaat
    19501 tgcttctttt gtaaacgtaa ctgacacatt ttctgtaccg atcaacgcga cgtattgttt
    19561 tactaaagca ttatttggtt cggtcagaat cttcacaaaa tcttcagctg tcaaatcatc
    19621 taattctacc cgtatcggga agcgtccttg aagttctgga attagatcac ttggtttaga
    19681 caaatggaaa gctcctgaag caatgaatag gacgtgatct gtttggatga tcccgtattt
    19741 tgtgtttact tgtgaacctt cgacaattgg caatatgtct ctttggacgc cttctctgga
    19801 tacttctcca gattgctgtg atttagaagt gatcttatcg atttcatcga taaaaataat
    19861 tccactttct tccgctaatt tgattgcctc actatggata tcagcatcct tgactaattt
    19921 tgctgattct tccttgatca ataactctaa agcttctttg actgttaccg tccgttccac
    19981 ttttttcttc ggtgtcaaag cacctagagt ttcatttagg tcgatcccca tttgctccaa
    20041 tccattgttc atcattggtg caggtttctt ttggtcttca acttcaatgg ttacttcacg
    20101 actatccagt aaaccctttt gtagttgttc caagactgta cggcgattga ttcgaatatc
    20161 ttctgtcact tcttcttgcg gttcagcggt attttgctga ctagcattaa aaagattcat
    20221 catttgttca aattgattag tggattgttt ctgttctttt ttgataccag gtaccaagat
    20281 ttttaccaaa cgtttttctg catttttttt agcacttgtg tatacacggc tgtactgctc
    20341 tttttctacg atttggatcg cattttctac taaatcccga accattgatt ctacatctct
    20401 tccgacataa ccgacttcag taaattttgt tgcttcgact ttgacaaatg gtgcattgac
    20461 gatttttgcc aaacgtcgtg cgatttctgt tttaccgacc cctgtaggtc cgatcatcag
    20521 catatttttt ggtgtaatat cttgttgcat tttttcatct aactgcaaac ggcgatagcg
    20581 gttacgcaaa gcaacggcaa cagatttttt tgctgcgtgc tgtcctacga tatattcatc
    20641 taattcactt acgatttgtc ttggtgtttg ttttaattca tacatatcta ctcacctctt
    20701 acagttcttc tacgataata ttatgattag taaagataca gatatctgcg gcaatattta
    20761 acgcattttc tgcaatttct ttcgcactca tgtcgttttg agcatagttt ttcattgctc
    20821 gggctgcagc caacgcaaaa ttccctcctg atccgatagc taagatacca tcatctggtg
    20881 tgataacttc tcctgtacct gaaacaagaa gcatttcttt atcattcatt acgatcagca
    20941 tcgcttcaag tttttgcata gattgctgtg tccgccattc ttgagctaat tcgacagctg
    21001 cgcgttgtag attcccgtta tattcgttta gtttgccttc aaatttttct tctaaagtaa
    21061 acgcatctgc aacacttccg gcgaaaccta caacaacttc tccattgtag atacgtcgta
    21121 ctttctttgc agtgcctttc atgacaacag attcacccat tgttacttgg ccatctccag
    21181 ccatagcaaa tttcccgtct ttttcgacgg cacagatagt ggttgaatga aatggtgatt
    21241 cgaccatgtt tgtttcctcc taaatttgtt cttttcctta tttttacgct cttggatgga
    21301 aagaacgata gtttttttgt aaactttctt ttgttacatg ggcatagatc tgggtagtcg
    21361 ataaattggc atgtcctagc aattcttgga ctgtccgcaa atctgcccca ttatttaata
    21421 aatgagtagc aaatgtatgg cgcagcatgt gaggatggat atcactatcc aaactgcttt
    21481 ttttgatcat ttgattcaag acatattcaa ttccagtagg cgtgattggt tttccatgat
    21541 gattcacaaa aacgatatca tgctcttcgt gatattttgt catcaatacc tggcggcctt
    21601 ccctgaaata ttcttgcaga gcatcttgag caaaagaacc tagaggagca tatctctctt
    21661 tgttcccttt accatggatc aacatgacct ctgaatcaaa atcaatgtct gataccgaca
    21721 aactgctaca ctcacttaaa cggatgcctg acccgtaaag gacttccagt aaagcgcggt
    21781 tcctcaaatc caaaggacta tctcctgcta cgctgtcaaa aagtgcttgc atttcatttt
    21841 cataaaaaaa acgtggcagt ctcaaatttt tctttttgag atgaacgtaa gaaaatggat
    21901 tttcttttat cacttcttct ttgagaagat actgataaaa cgaacgtagg ctggctatct
    21961 tgcgactgat agaatttctg ctatagctag gacgatgatc agctaatgca ctcaaataga
    22021 cacgaaccgt aaaatattcc gccttcagca gatcagcgtc tccagattcc tccaaaaaat
    22081 gtttgaaatg gagaatgtct tcttcatatg cttctttcgt tttttctgaa tatcctcttt
    22141 cgacaatcaa ataacgcaaa aatttttgtt cccacgtggc ttctgtcatt ttctcacctt
    22201 ccttttgtcc cagagaataa tttagcacag cgtttataaa aagacaaata aattgtcaga
    22261 atttaaccaa tatttctaag tttgttcaca attggcgcaa ttcctcacat tttgtttgag
    22321 aaattcttaa gaaaaacgca agaaaaagag cgagactatc cgtctcaccc tcttcatgga
    22381 gtttccttac tcatttggga ttgcagtttt ttctaattct gtttttattg cctcattagc
    22441 ttttaaagct cgttgtgcaa ttgcttcata tcttgctttt ttgtctcgaa tgcgctctgg
    22501 cagttcagga aacagaccat agttggcatt catcggttgg aaatgttttc cttccgcatg
    22561 agtaatgtag taagccatac ttccaatagc tgtttcttgt ggaaactcga ctggttccat
    22621 ttcttttgct aagcgtgcgg cgttgattcc agcaagtagt ccgctcgctg cactttcaac
    22681 atagccttct acaccagtca tctgacctgc aaagaacaga tcttcgcgtt tcgttgattg
    22741 gtaagtcggt ttcagcaatt ctggcgaatt cataaagctg tttcggtgca tcacaccata
    22801 gcgaacgaat tcagcatttt ctaacccagg aatcatccgg aaaacacgtt tttgctcgcc
    22861 ccatttcaag tgagtctgaa agcccacgat gttgtataaa gaagctgcag cattgtcttg
    22921 acgcagctgg ataacagcat aaggacgttt gccagtttta ggatcttcca atccaactgg
    22981 tttcataggt ccgaaaagca tcgttttgaa tcctcgctgt gccattactt caattggcat
    23041 acatccttca aaatattttt ctttctcaaa agatttaagt tctgccactt cggcattgat
    23101 tagtgcctca tggaaagctt tgaattcctc ttctgtcatc ggacagttca agtaagctgc
    23161 ttctcctttg tcatagcggg acttcaaata tactttatcc atatcgatcg tagctttgtc
    23221 tacgattggt gcagctgcat catagaaata aaaaccatct gaaccattga atgctttgat
    23281 gctttctgct aatggatgag aagtcaaagg tcctgttgct actacggtga ttccttccgg
    23341 tatttcagta atttcttcgt ttatcactgt tactaatgga tgctctttga cttttcgggt
    23401 aattgtttca gaaaaagaat cgcggtcaac agctaaggca ccaccagctg gcactgctgt
    23461 ttcatctgcc gaagtgatta ctaccgaatt caatcggcgc atttcttctt tcaataaccc
    23521 tactgcatta gccaaactgt ttcctcttaa tgaattggaa catactagtt cagcaaaatt
    23581 acttgtgtga tgcgcctcag tcgatttgac tggacgcatt tcatataaac ggacagggac
    23641 tcctgcttgt gcgatctgcc aagcagcttc acttccggca agccctgctc caacaacatt
    23701 taccattttc aatgaaagaa cctcttttct attatttttg gatgtcttct tcgtaatctc
    23761 catttacaca gactacttgt ttaccgcctt tgactttctt ctcgaccaga tatccgtcac
    23821 attttggaca atttctgccc actggtttat cccaagaagt gaattcacat tctgggaaac
    23881 gggaacaacc atagaatagt ctgtttttct tagattttcg ttcaatgact tgtccttcat
    23941 gacatactgg gcaagtcaca ccgatttctt ttacgattgg tttcgtattc cgacaatcag
    24001 gaaaattact gcaagcataa aacttcccat atttccctaa ttttatcacc atcggatgtc
    24061 cacagacatc acaatcgaat cctgctggtt catctttgat ttgaattttt tcgatttttt
    24121 cttccgcatt cgtcagttct ttttcaaacg gtttatagaa acgatcaacc actttgaccc
    24181 acgcttccgt gccttcttca attttatcca aatctccttc catttctgct gtgaaatgga
    24241 tatcgacgat ttgagggaag aattcacaga ttaatgaatt gacaatttct cctagttcag
    24301 tcggctcaaa tcttttttgt gtcaatttta catagtagcg tctttggatc gtatcaagtg
    24361 ttggtgcata agtggaaggt cgccctaccc cgttttcttc tagtgcacga atcaacgtag
    24421 cctcactaaa acgtgctggt ggttgagtaa aatgttgttt tggttcaata tcaacagatt
    24481 ggactacatc gccttcttca agttctggaa gaatattttc tttctcttct ttgccgtcat
    24541 ctctaccttc cacatacact tgcatgaatc ctttgaattt gatttttgaa ccgttcgcaa
    24601 tgaagatgac accattttgt tctaatgtca ctttcattgt atctaaaata gctggtgtca
    24661 tctgactagc cacaaaacgt gaccagatca atgtataaag tttcaattga tctttatcta
    24721 aatattgttt gagttcatct ggtgtacgaa gcacactcgt tggacgcaca gcttcatggg
    24781 catcttgtgc gccttgagca tttttgatct ttcggtgatc atgtctagaa aattcttttc
    24841 catacgtatc ttcaataaat gctgcggcct ctgcttttgc tgtatcggca atccgggtag
    24901 aatcagtacg catgtatgta atcaagccga ctgttccttg tttacccaaa gtgattcctt
    24961 catataattg ctgtgctacc atcatggttt ttcttgttcg aaagtttaac ttacgggcag
    25021 cttcttgttg caggctactt gtagtgaaag gattcgcagg gtttcttttg cgctctttct
    25081 tttctacttt tttaacttcg aagtctgttc catcaattct agcagtgact tcttttacac
    25141 tttgtgcatc tggtaatttc tttttcttac cgtcgattcc ccagaaattt gctttgaatt
    25201 tcttgcgagc ttttttaaaa ttaccgtcga tgctccaata ttcttctgga acaaattctc
    25261 ggatctcttt ttcacggtca ataataattt ttaaagcgac agattggaca cgtcctgcac
    25321 ttaacccttt cttgacctta cgccagagaa taggactgat cgaataacca acgattctgt
    25381 ctaaggtacg acgagcttgc tgtgcatcta ctaaatctac atcgatcgtt cttggttcct
    25441 taaaagctgc tttgactgcg tcttttgtga tttcattgaa gaccacccga tttttttctt
    25501 tcagatccaa cccaagtagg tacgctaaat gccaagcaat cgcttctcct tctctatccg
    25561 ggtcacttgc caagtaaact ttttgagctt tttttgctgc ggctttcagg cttttgatga
    25621 catcgccttt tccgcgtata gaaatataat ggggttcata attgttttca aaatcgatac
    25681 ccattttact tttcggtaaa tctcttatat ggccaacact ggccattact ttatagtttc
    25741 gtccaagata tttctcaatt gtcttggctt ttgcaggtga ttctacaatc actaaatatt
    25801 tatacgccat tactgaatgg actcctttcc attgtcgtgt tcctactatt aaaagaggat
    25861 tcatacaaat cgtagctaat catatccatt cagaaaacgt ttgtcaagaa aagcaaatga
    25921 aaagtatggt gttattcttt aaattctgcc aagatatctt cacccgaaac cgtgcaaact
    25981 gcaccgtctt ggatcaaatg atgacatccg gtagaatgtt ctgttaaaat atttcctgga
    26041 acagaaaaaa ctgttcttcc aagatccaat gcttgctgtg ctgttatcag agagccgctt
    26101 tttttcttgg cttcaaagac acatgttcct ttagacaaag ctgcgataat ccgatttctc
    26161 attggaaaac aatgcttttt cgggccggat tgaggaggat attcactcaa aagaagatga
    26221 tcatttgcaa tcacctcttg caagtcacga ttttcagcag gatagacttg ctctatccct
    26281 gttccaatga ctgcgattgt ccgtccacca tgagagattg ctgcttggtg accgtatgta
    26341 tctatccctt tcgcgcagcc actgacgatc acatatccag cttctatcac tggttttagt
    26401 aaataataaa ctgttttttt ggctaaagca gaagtgtgtc ttccaccaac aacgcttaac
    26461 atgttacaag aaagtaaaga tagatcacca ttataaaaca gtacaattgg cggataggtc
    26521 aagtgaagca gctgaggggg atatttggga tcaaagcaag tgataaacga ctgtttcgat
    26581 tggattttgc cccagttagc gtgaatttcc tgccaacttt tgcgaaacag ctcccggtgt
    26641 ttggttattt tacctatctt aatgatgtct tcaaatccga tttctttata aggatactgc
    26701 atcatccagt tagcaagtgc ccattttcct tgactactga ttccttttgt ataagcaagt
    26761 ttcaataaat tttcttctat ttgatacatc ataaaaccgc ctttcgtctc tctttctaat
    26821 aagatacgta aaagcggctg ttttttattg taaatatttt tttacaggtg caaaactttt
    26881 acgatggatt ggcgtaattc cttgtcgttc aagtccttct aagtgttcct ttgttccata
    26941 acctgcatta tgcgagaaac catatccagg ataaagcacg tcatattctt tcatcaattg
    27001 gtctcgatat actttagcaa tgatacttgc agcagcaatc gacacagatc gtgcatcccc
    27061 tttgattatt ttttcctgct gaataggcaa atccaaggtc atcgcatcga tcaacaaata
    27121 gcttggtaca atggacaatt tttctactgc ttggatcatc gctaatttac ttgcttcata
    27181 aatattcaca tcatcgattg tctgctgatc aacgatcccg atcccgattg ccagggcttt
    27241 ttcttgaact tgttgataaa gaagttctcg ctttttctct gataattgtt tggagtcatt
    27301 cagccctaat atgatctcat ttttcggcaa gataactgca gctgccacga caggtccagc
    27361 taatggtcct cttcctactt catcaatgcc ggcaatccat tggtgacctt gtgcgtaccc
    27421 ttgcttttca aagcaaaaca tttcttcata tttttcctta attaatgctt cctttttcaa
    27481 tcgtcgttca aaagaagcca gtgcttgctg cacgcctttg cgtggatcat ttcttaatga
    27541 ttctagtgta ggatcatcta ttctctgtat gcttttcaat cgttctttga tactttggat
    27601 ggattcagtc atcacttttt tgctccattt cttcgcaacg atccagtgtg tatcgtccaa
    27661 gttttccttg acgaatatca tgcacgacta attcgctgcc acgatcatag tcttctttat
    27721 acccacgttt tgctgtaata tccatcagta attccggtgc caatttttct tcttgctcga
    27781 ttgataaacc ataacgatcg ctgattcttc ctgaataata tcgggcaaaa aagtctaatc
    27841 cgtaaatcgc taaatcatct aaatggacaa gctggtcttt gatcgcgcct gtcagcgcta
    27901 gttttttgcc gatttcttca tcttcaaatt tgggccataa aatccctggt gtgtctaaca
    27961 attccaactc attacctaaa cgaagccact gctgaccttt tgttacgcca ggcttatttc
    28021 ctgtctgtgc aattttcttg cctactagtc gattcatcaa cgtagatttc ccaacatttg
    28081 gaatacctaa gaccattgcc cgaatagcgc gaggcttgat cccccgagca gcatctcttg
    28141 cccgtttttc tttcaatgct tctttagccg caggtactag acctttaatt cctttacttt
    28201 cttgtgccgt gatagctaat gcaagatggc cttgtttacg aaaatattct tgccacagct
    28261 ttgtctgttg tggatctgcc agatccgctt tattcaataa aacaaggcga ggtttttgct
    28321 gaatgatctg atctagcatt ggattacgag aagataaagg taatcgtgcg tctaccaatt
    28381 caaatacgat gtccacatat ttcatttttt cagaaacttc tcgtcgggct tttgccatat
    28441 gtcccggaaa ccattggatg gtcattgttc tctccattcc tttcataccg gaatattccc
    28501 cggctttact tgtttttttc tttttcaata taaattcact tttttattat aaagaaattc
    28561 catctattag ttaagtgaaa gtgaaccagt cctcattcta tcacatcttc acttttttga
    28621 tgatgcaaat ttttattttg gtttctatat atgaatctaa atttttgaca gcgtttccta
    28681 aataagagat gatagacgaa caaaacagaa aggagacgaa acaaatgaat agtatggttt
    28741 ttgttaattt tcctgttgct gatgtcaatc gttccgttgc tttttatgaa aagctgggtt
    28801 ttaaaaaaaa tgaagaattt tctactgaag aagctggttc a
//
LOCUS       DACGEU010000030        28773 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.030, whole genome shotgun sequence.
ACCESSION   DACGEU010000030 DACGEU010000000
VERSION     DACGEU010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 28773)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28773)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28773
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.030"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            134..3661
                     /locus_tag="IXR40_001227"
     CDS             134..3661
                     /locus_tag="IXR40_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HAQ4361088.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3658..7380
                     /gene="addA"
                     /locus_tag="IXR40_001228"
     CDS             3658..7380
                     /gene="addA"
                     /locus_tag="IXR40_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HAQ4361089.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLAKRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7449..7790
                     /locus_tag="IXR40_001229"
     CDS             7449..7790
                     /locus_tag="IXR40_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4361090.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8099..9142
                     /gene="pheS"
                     /locus_tag="IXR40_001230"
     CDS             8099..9142
                     /gene="pheS"
                     /locus_tag="IXR40_001230"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HAQ4361091.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIERKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9147..11567
                     /locus_tag="IXR40_001231"
     CDS             9147..11567
                     /locus_tag="IXR40_001231"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HAQ4361092.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11737..12747)
                     /gene="trpS"
                     /locus_tag="IXR40_001232"
     CDS             complement(11737..12747)
                     /gene="trpS"
                     /locus_tag="IXR40_001232"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HAQ4361093.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            13001..13738
                     /locus_tag="IXR40_001233"
     CDS             13001..13738
                     /locus_tag="IXR40_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAQ4361094.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            13752..14567
                     /locus_tag="IXR40_001234"
     CDS             13752..14567
                     /locus_tag="IXR40_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HAQ4361095.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            14580..15227
                     /locus_tag="IXR40_001235"
     CDS             14580..15227
                     /locus_tag="IXR40_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAQ4361096.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            15243..15899
                     /locus_tag="IXR40_001236"
     CDS             15243..15899
                     /locus_tag="IXR40_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAQ4361097.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            16061..16882
                     /gene="racE"
                     /locus_tag="IXR40_001237"
     CDS             16061..16882
                     /gene="racE"
                     /locus_tag="IXR40_001237"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HAQ4361098.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            16885..18240
                     /gene="rph"
                     /locus_tag="IXR40_001238"
     CDS             16885..18240
                     /gene="rph"
                     /locus_tag="IXR40_001238"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HAQ4361099.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            18241..18759
                     /locus_tag="IXR40_001239"
     CDS             18241..18759
                     /locus_tag="IXR40_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HAQ4361100.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            18866..19366
                     /locus_tag="IXR40_001240"
     CDS             18866..19366
                     /locus_tag="IXR40_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAQ4361101.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(19646..20566)
                     /locus_tag="IXR40_001241"
     CDS             complement(19646..20566)
                     /locus_tag="IXR40_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HAQ4361102.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            20731..21744
                     /locus_tag="IXR40_001242"
     CDS             20731..21744
                     /locus_tag="IXR40_001242"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HAQ4361103.1"
                     /translation="MQIDWNNLGFSYIKTPWRFIAKWKDGQWEEGELTEDNYLTIHEG
                     SPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLMPMVPEKMFVDAVK
                     QVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVFCTPVGAYFKGGLK
                     PTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCVYLDPATHTKIEEV
                     GAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIEGDIFIDDLDQFAE
                     AGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGIQFGDIEAPEGWIE
                     VVE"
     gene            complement(21854..22609)
                     /gene="fabI"
                     /locus_tag="IXR40_001243"
     CDS             complement(21854..22609)
                     /gene="fabI"
                     /locus_tag="IXR40_001243"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HAQ4361104.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            22829..23269
                     /gene="fabZ"
                     /locus_tag="IXR40_001244"
     CDS             22829..23269
                     /gene="fabZ"
                     /locus_tag="IXR40_001244"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HAQ4361105.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            complement(23384..24145)
                     /locus_tag="IXR40_001245"
     CDS             complement(23384..24145)
                     /locus_tag="IXR40_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAQ4361106.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            24334..25428
                     /locus_tag="IXR40_001246"
     CDS             24334..25428
                     /locus_tag="IXR40_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HAQ4361107.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
     gene            complement(25514..26473)
                     /locus_tag="IXR40_001247"
     CDS             complement(25514..26473)
                     /locus_tag="IXR40_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element IS6770 family transposase"
                     /protein_id="HAQ4361108.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDVIIGRKERSVS
                     CGMRTLYRLFSKGIFDIDTLPMKGKRKPNGHQEKRGKQQYQRSIHDRPDNYPDFNSEF
                     GHLEGDTIVGIHHKSAVITLVERLSKVIITIKPNGRKALDIETALNQWFSRFPKNFFK
                     SITFDCGKEFSNWKAISNQHDIDIYFADPGTPSQRPLNENSNGILRRNGLPKSMDFRK
                     VNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAFYSSLI"
     gene            complement(28024..>28773)
                     /locus_tag="IXR40_001248"
     CDS             complement(28024..>28773)
                     /locus_tag="IXR40_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAQ4361109.1"
                     /translation="KSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPISCSA
                     RTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEFGHL
                     EGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFKSIT
                     FDCGKEFSNWKQISNVNDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNSVDE
                     FFIQSVASKRNNIPRKSLDYRTIIEHLWKYF"
BASE COUNT         9424 a         5056 c         5867 g         8426 t
ORIGIN      
        1 ttttttgcgt atacttaaaa aagtagaaat atcagaacct taaaaggata taatttgaag
       61 aatatagaac aaatgttcag tattttttga tataataaag gagcaccgta tcatgtgttg
      121 aaggaggaaa agcatgtctt tacaatttat tcttggaaac gggaaaaaag atcaccgtca
      181 agtcttgatc gacgaagcat ccgcttggct cgaccaggat gcaagtaacc aagtattttt
      241 ccttgttccc aactacagca aattcgaaca ggaacaagaa attttagcgg agatgcgaag
      301 aagaagcgga aaaaaaactt tcagcacaac aaacgttcaa gtatttagtt tttatcgtct
      361 ggcttggtat ttgctgcaac agacaactct tcttacagga aatgaattat cagaatcagg
      421 atctgcaatg atcttgcgac agattttaga aaaaaatgag gaagaattaa caatctttcg
      481 cggagaaatc aataaaagag ggtttattcg tcaattacaa gaactctaca gtgaattgcg
      541 tacaggaaat attcaaccag aagacctgat gcttttattt ggtgattcac ctaatgcaga
      601 agaccagcaa cttaaaatga aagacttgaa gctgattttt tcagcttatg acagcgaatt
      661 gactcaacgt gcactaacaa atgaagatgc actatctata ctagcaaatt atatgcagac
      721 acaagatttc aacaacgtca aatttattgt cagtggtttt tctcgaatca atggtcaaga
      781 gtatcaatta ctgcaggcaa tgatggaaaa ggggcaattg gttgtcgatt tattgctgga
      841 tcgtccttat acagcggatc ttccagaagt acttacgctc tttcatgaga ctggaaagct
      901 ttatttccgt ctttttcaaa gtgcaagaga acggaaagtc cctatattag tggaccgatt
      961 tgcaccagag cagactcgtc cgacagagct tcaactgctg caaacaatgt gggaagagac
     1021 atctagccaa aagaaagcgg cagtacacaa aataggggga caagagcatc tccatttgtg
     1081 ggaagctgaa aatccaactg aagaagtccg acaattagct gttgaaatca gacgactagt
     1141 cagtgaagaa aactaccgtt atcgtgatat ccaagtgctg acaaaaaata tgtctttata
     1201 tggaaatatc cttcggccga tctttcaaga aatggcaatt cctttttata tcgatgaaga
     1261 acaaatgatg gaaaatcatc cgctgatcga atggatcaac agtctgttcg ctcttgaccg
     1321 ctattcttat cggctaagtg atattatgcg ttttttcaaa actgaattat ttctgtcgac
     1381 ggaagcagaa accgaacttg atgaatggaa acaagagcga gatgaattca ggaaaaaact
     1441 ggacatcact gaaaatgtag cacttgctta caattatcaa ggaacttatt ggactcgtga
     1501 aaaagactgg cagtttgtgg cgtatgattt tgaagcagaa cagattgaag acgtacagta
     1561 tttggaagaa cagtcaaata cgattagacg attatttcag aaagctgtac cagtattttt
     1621 gaaaaaaata aagaaaagca aaacaggaca agaggccgca aatgtttttt atcaattttt
     1681 gatccaaagt ggcgtacagc aacaattatt gttttggcgt aatcaggaag tagacagagg
     1741 aaacttagaa gcggcaagaa accatgagca gacatgggga gcgctgattg atctgttgga
     1801 tgaatatgta gtaatttatg gtgaatcggc ttttgactgg tcactgttcc aagaaatcat
     1861 tacaagtggt ctagaaaatc taagttatgg taaaatccct accgcaatcg accaagtgcg
     1921 aatcaatcgt ttggaattag ttcgaccaaa tcaagctgcc gtcacttttg cattagggtt
     1981 gaatgatcaa gtgtttccag accgaaaaga gacaaaagga ttgttgtcca gtgaagaacg
     2041 agaagtatta aatcaggcct tgccagatgg acagttttta ttcgacccat caaaggaaag
     2101 tatctctttt gagcctttcc aagcctatct tgtttttctt tccggaacag atcgattata
     2161 tcttagttat gcacaaagct atgacacaga tggttcgctg aagatgtctc cttatttgcg
     2221 tagaatcaca gaatatttat ctgttcccgt cgagagaaaa gagcatttga cgatcgaaag
     2281 cgaccctaat tgttatgtag ggacttacag aagcggaatc aatacagtca ataggattta
     2341 tcgattagct ttagatgaaa aaaaacctgt accaaagcac tggcaaaagc tcaaagaatt
     2401 agtactgaat tcgtcatggc gaaattttgc tttacagatt tttgaaagtc aggaacattt
     2461 aaatgttcct gtttcgatgc cagaaaaaat ggcggaagag ctttatggaa aagagattta
     2521 tacttcaatt tcacgtatgg agaattttta taattgtgaa tacaaatact tcatgcaatt
     2581 tggtttgaaa ttgaaagaac gaactgttta tggtctaact ccagcagcaa ctggtgattt
     2641 ttatcatgaa tcattggatc gtttcttcaa gctactgttt tcaaaccaat tatccttagt
     2701 gaatatgtcc gatgcgcagc gtagagactt tactgaaaaa gtgctgcagg aagtattcgg
     2761 agaacttcgg tttgagatat tggatagttc tgcaagaatg aactatatcc gctaccagtt
     2821 aggacagacg attcaaaaag tgacatgggc tttgcaaaaa cagagcaaaa atacaggcat
     2881 gcatcctctt cagacagaga ttctatttgg tcagattgct ggagcaaaag gtatcacagg
     2941 tctggaatta ccgttgagta atggtggaaa actccatgtt cgagggaaaa tcgatcgaat
     3001 cgatgtagct tctgaacaag aagatacttg gctaagcgtc gttgattaca aatctagcgg
     3061 acgttcattc gatgtcacag aagcttatta tggcatggct atgcaattat tgacgtatct
     3121 ggacgtagca ttgatggatg cggtacgttt gactggaaag gcggctgtta aaccagcagg
     3181 atcatattat ttacatgttc ataatcctgt attgacggag acagatgatg tagagaagaa
     3241 tacattgaaa aaatttagtt atgatggcgt ttttgtcgat gatcccgctc ttttagaagt
     3301 actagatcat tcactggaag caaaagaaca atcactgatc tatccagtga aaaaaaatgc
     3361 gaaagatgaa taccaaaaag gtagtttcag taaagacaaa tttttcacgg aagaagaact
     3421 gcaactattc atggcgcata atcgggaaaa tatgcggtta gctggagatg cgattacttc
     3481 cggagaaatc aaactaaatc cagcttataa agataaacag cggattgcct gcgaattttg
     3541 tccattcaga agcatctgta cgtttgatgt gatgctgaaa gaaaataatt accaccgtct
     3601 ggagaaaata gataaggaag aagcactgcg tagaatattg aaaaggagtg aagaagagtg
     3661 aatcaaattc ctttaaaacc gcaaaatgaa cgattcacag atgatcagtg gcaagcgatt
     3721 tttgatcaag gagataatct attagtctct gcgtctgccg gatcaggtaa aactacagtg
     3781 cttgttcgaa gagtgattga aaaactaaaa atgggttttg atatcgatga attattgatt
     3841 gtgacattta ctgaagctgc cgcaagagaa atgaaagaaa gaattcaaga ggcattacaa
     3901 gaatccgtca atagcgaaag tgaccctgta cgtagacagc attttactaa gcagttagtt
     3961 ttattgccca cagcgaatat ctcaacctta catgcttttt gcctgacagt tattcgacgt
     4021 tattattact taattgatat tgatccagtc tttcgcatgt taacagatga aacagaaacg
     4081 atcttgatga aggaggatgt gtgggacgag ctgagagaag cactttatgc agaaaatgat
     4141 gaacgatttt tccaattaac aatgaatttt tctaatgatc gttcagatga cggcttgacg
     4201 aatctggtgt tttctcttta tgagtttgcc cgtgccaacc ctgaccccca aaaatggcta
     4261 gaacagttaa gcgataatta tcgtttgcct gaggggctag cgaaatctcg attatatcaa
     4321 aaacaaatcc gtcctttagt tttggcagat atataccaat gtgtacagtt atatgaacag
     4381 atgactcagt tagcacaagg tgaaggatta gaaaaaatgc atgagcaagt agctggagaa
     4441 caacagcaga tcaagaatat ctatgaagcg ttctcgcaag atcggttaga agaagcttat
     4501 gctggtttgg aacaactaac tttttcaact tttaagagca gtcggaaagc agaattgaaa
     4561 gaaatttcca atgaagtcaa gggcatgagg gataaagcaa aaaaactgat tcagcagata
     4621 agtaaaagtt attttcctgt ttccccaagc caaatggaag aattaacgga caaagcacta
     4681 ccgttagtcg aagaaatgac aaaagtcacg caaagcttca tggacggttt cagtatgcgt
     4741 aaacgggaaa aaggtgtgct ggatttcaat gatctggaac atttagcgtt gcagattctc
     4801 acagaaaaaa cgaaagatgt atggctgcca agtgaagctt caaaacatta tcgaaaaaaa
     4861 ttcaaagaag taatggtaga tgaatatcaa gacgtgaacc aattacaaga agccatttta
     4921 tactggctaa gagaacccga tgatacaaaa ggaaatatgt tcatggttgg ggatgtcaaa
     4981 caatccatct attctttccg tttagcagat cctagtttat ttatcgggaa atacgagaat
     5041 ttctcaaaga aagaaggcgg acgtcgaatc gttttggctg agaacttccg ctctagaaaa
     5101 gaagtccttt cttttacgaa tcttattttt gaacaactaa tggatccagc agtgggtcaa
     5161 atcaattatg acgaagcagc caaactgatc caaggatttt cagactttcc agagaatgaa
     5221 cagtttgagc cggaaatcat gatctatgaa aaagaacagg aagaatcaga gattgagatt
     5281 ccgacggatg atatactgga agacaaaaca gaaggcgaac tttttatgac aggactaaaa
     5341 attcgtcaat taattgattc ctcctttatg atttatgata aaaaatcaaa aaaaagtcgt
     5401 ccgatagagt acaaagacat tgttctcttg acacctacaa agaagaacaa cttaacgatt
     5461 ttagagattt tcaaaacatt ggatattcca ttagagatga atgatgctca aaactatttt
     5521 caagcgacag aaattcgcac gatgatctcg ctgctacaat taatcgataa tccctatcaa
     5581 gatattccgc ttgcggctgt attgcgctca ccgatcgtgg gtctgattga accagaatta
     5641 gccagcattc gattagctaa acgtgcacat acttactatg atgctgtgct tgcttatcaa
     5701 gcatcaaacg aagatgaatt agcagctaag ctggaacatt ttggcaagca actagagcat
     5761 tggcgagaac ttgctcgccg ttcttcgatc actgacttgt tatgggatat ctattatgag
     5821 acgggatatc tagagtatgt ggtcggtctg ccagcagggg cacagagaca agccaatctt
     5881 tatgcattgg ttgatcgtgc caaagcttac gagcaaagtt ctttcagagg attataccag
     5941 ttcgtgcgtt tcattgaaaa aatgcaagaa aaagataaag acttagcaga accagtcatt
     6001 tcaatagaag ataatgctgt tcgcgttatg acgatccatg caagtaaagg cttggaattc
     6061 ccagttgtat ttttgttaga tatgacaaag gagttcaact tacaagactt gcgcaatcgg
     6121 tatgcttttg aagaaaaact tggagcagga attcgctata tggatcctga aacacgagtg
     6181 ttatatgata cgttaccgtt tcaagccatc aaattggcaa agcaaaacaa attgttgtcg
     6241 gaagaaatgc gtaaattgta tgtaggattg actcgggcag aacaaaagct tttcattgtc
     6301 ggttcctata aaaataaaga gcaaatgatc caaacgtggt ctgaagcagc tgatcatgag
     6361 gagttagttt ttgatcctgc gctacgtttg aagggcagaa gcagcttgat gaattggatt
     6421 ggttacggat tgatccgtca tcctgaaatg cagaaatact tagaggaaga aatttcgact
     6481 tctcttcttc aacattcaaa tgcacagttt tctatttcat ggatgaatca gcaatcgatc
     6541 attgaacaaa gacagttgct tgctgaaaaa gaactggtta acttagatca gcagatgaaa
     6601 gaagatgaaa ctttattagc agattcgtta caaaaacgtc tggcatatga atatccttat
     6661 caagcttctt cacaaaccac aagttatcaa tctgtatctg aaatcaaacg attattcgaa
     6721 gatccagatg atacacaaga atcacgtttg actctggaaa gcagtcagaa caaagcagca
     6781 tcccgtcaat ttcgttatac gcaagaacaa ctagcagaac caaaattttt gcaaaaagat
     6841 cggcaagtgt cagcagctgc tgttggaact gctacgcatg ctttgttaca attactgcca
     6901 ttagagatgc caactacaga gagtatccat caaaaattac aggaattggt aaggaaacgg
     6961 ttagtagacg aaaaagtcgc gaaaaaagta gatgtttctt ctattatatg gttctttcaa
     7021 acagaacttg gtcaacagct gattgccaac aaagaaaacg taaaacgaga acaacctttt
     7081 tccatgctgc ttcctgctga cgaagtattt caagactatc caaatcaaga agatgaacta
     7141 ttaatccacg gaatcgtcga tggataccta gaagaaaaag atcatctcaa tatctatgat
     7201 tttaaaacag attttatttt acatccggat gatccagcag aaatagatgc aatcgtccaa
     7261 aaatatcaag gacagctaag actttaccaa caagcaatgt cagaagcttt gaataagcca
     7321 gtagaaaatg ttttcctaat tttgcttcga gtgaaacaaa ttataaacat taacaaataa
     7381 ttataattga gcaaacttga cttatgtttt gtaaggatta tgctatactc tgggaagagg
     7441 tgagtatgat ggagctaaca cagacagaat tcgttttatg ccctaaattt gaaaaaacat
     7501 tctctatttt aggaaaaaaa tggaacggat tgattatcga tgtactactc gaaaacggtc
     7561 cgcaacgctt tgttgagctt gcggcaaaaa tcccgatggt cagtgatcga gtattagtcg
     7621 aacgcttgaa ggaattagaa aaagaaggaa tagtcactcg aaactttgcc tgtagcgaaa
     7681 agagccgttc agaatatctc ttgactgaaa aaggagcaga cttgcaaaaa gcgatgcgtc
     7741 aaatacaagt ttggagcgaa aaatggatca cagaggaaga atgcggttga ttttgtaaaa
     7801 aaaatcttgt aaactatagt ccatacgaat aagtaaagaa cgatgacgaa aaagagtagt
     7861 ttggctaaac cagttcaggg agatctgtcg cagactgaaa gcagatcctg tgtttgaaaa
     7921 atgaagttca ctttccgagt tcgtctgata aaatcagacc ggcaattgtc gttaacgaag
     7981 taagagtgcg gtgtaagtca tttatccgca aattaggatg gtaacgcgaa gacctcgttc
     8041 cttaacagga atgaggtctt tttgttttgt atttggaatt taaaggagga acaagcacat
     8101 gtctctacaa gcacaattag agagcttgaa agaagcaacg ctcgtcaaaa tcacagcggc
     8161 acaagattta aatgaattaa atcaaatacg tgttgaaacg ttaggaaaaa aaggaccgat
     8221 cacagaagta ttacgtggga tgaaagatct aagtccagaa gagcgaccaa aagtcggaag
     8281 tttcgcaaat gagatccgag atcttttgac agaagagatc gagcgaaaaa aacaagtatt
     8341 agaagaagaa gcgttaaatg cagctttggc aaaagaaaca atagacgtga cactacctgg
     8401 tagaaaagta aaacatggta cacgtcatat cgtgacacaa atcatggaag aaattgaaga
     8461 tatttttgtg ggtatgggct atcagatcgt agaaggatat gaagtagaat ctgatcatta
     8521 caatttcgaa cggatgaatc tgccaaaaga tcatccagca agggacatgc aagatacttt
     8581 ctatatttca gacgagatat tgattcggac acatacttca ccagtccaag cacggacaat
     8641 ggaaaaacat gatttctcta agggtgctct acgaatgatc tcgccaggga aagtcttccg
     8701 cagagataca gatgatgcga cccacagtca tcagttccat caaattgaag ggctagttgt
     8761 tgataaaaac atcacaatgg gcgaccttaa aggaacatta gaagtcgtaa tgaaaaaaat
     8821 gtttggggaa gatcgtgaaa ttcgtttgcg tccaagttat ttcccattta cggaaccatc
     8881 agtagaagta gatgtcagct gtttcaaatg tggtggtgcc ggttgtaacg tatgtaaata
     8941 cactggatgg atcgaaattt taggagctgg catggtacac ccgaatgtgt tgaagatgtc
     9001 aggaatcgat ccagaagaat attcaggctt tgctttcggc cttggaccag accgcgtagc
     9061 tatgttgcgg tatggagtga atgatatccg taatttctat caaaatgact tacgtttctt
     9121 aagtcagttc aagggggagt aagaaaatgt tagtttcata taaatggctc aatcgttatg
     9181 tagatttatc gaatgtaaca ccaaaagaat tagcggataa gatgtctgtg acaggaatcg
     9241 aagtagaggg agtaacggtt ccagaagaag gcttgaaaaa aatcgttgtc ggtgaagtca
     9301 aggaatgcgt accacatcca gattctgatc acctttctat ttgtcaagtc gatattggcg
     9361 aagacgaact gtctcaaatc gtttgtggag cgcctaatgt gaaggttgga atcaaagtga
     9421 ttgttgcact tcctaactca cgtatcgctg gtaatgtaaa aatcaaaaaa ggaaaaatgc
     9481 gtggccaagt atcaaatggc atgatttgct cattacaaga aattggctat tcagatagtg
     9541 ttataccgaa agaatacgct gaaggtatct attatatgcc acaagaagct gtaaatggcg
     9601 atccagtttt tccttatttg gatatggatg attcgattat tgaattatct atcacaccga
     9661 atcgtgcgga tgcattgtca atgcgtggcg tagcttatga agttggggca atttatcgtc
     9721 agactcctac attcgatgac gaaaagctgg tagaatcctc acgtcctgct agcgataaaa
     9781 ttcaagtgga agttgaagat aaagaagcag ttcctgctta tcaaatcaga atcattgaag
     9841 gagtaagaat ccagccaagt cctcaatggc tgcaaaatct tttgatgaac gaaggcattc
     9901 gtccaatcaa caatgtagta gatgtgacga actatatttt gcttttattc ggacaaccac
     9961 tacatgcatt tgactacgac aaattgaaat caaaagagat ctttgtccgc cgtgcaaaag
    10021 aaaatgaaac attagtaaca ctagatggag aatctcggga attgacaact gacaatctcg
    10081 tcattactaa cggcaaagaa ccagttgctt tagctggtgt catgggaggg ttagactcag
    10141 agatcacgaa tgaaacaaca acagttgcac tagaatctgc tttatttgat ccaatttcga
    10201 ttcgtcgtac agcaaaacaa tttaatttgc gtagtgaatc ctctgcacgt tttgaaaaag
    10261 gaatcaacca tgcgactgtt ggagaagcca gtgaggttgc tgcagcaatg atcgtttctc
    10321 ttgcgggtgg ggaagttcta caaggcgcgg tcaaaggctc agagatcaaa gcagaagacg
    10381 tatcagtgaa gatttcactt gaacgcatca atcaatattt aggaacatct cttgtcgtta
    10441 aagaagtaaa tgagattttt gaagcacttg gatttagcta tgaagaaaag gagtatgttt
    10501 attccgtagt agtaccacca agacgctggg atatccaaat cgaagcagat attatcgaag
    10561 aagttgctcg tatttatgga tacgaccagt tgccatctac acttccaagt ggagaaacgg
    10621 ttgctggaag cttgtcaaaa gaacaagaaa ctactcgtaa aattcgtaca atctttgaag
    10681 gaagcggatt gagcgaagca atcagttatg cattgacaac agaagaaaaa tcaagacagt
    10741 ttgttataaa tgaaagtaat attacacgtt tggactggcc aatgagcgaa gaacgttctg
    10801 tattacgaat gaatttgatc agcggactat tagatgatat cagttataac actgcccgaa
    10861 aaaatacaga gattgcttta tatgaaattg gtcgggtgtt cttccaagaa aatgatccac
    10921 gtacacatct gccgcaagaa gtaaaacatg cagcaatcgc tatttctggt atttgggaag
    10981 aaaaagattg gcagacgaaa gctcaaaatg tagacttttt caccatcaag ggtcttttag
    11041 aaaacttatt tgaacaacta ggcatcactg aagatgtcca ttatcaaaca gtgacagaaa
    11101 tgaaggaaat gcatcctgga agaactgctg cgatttacct tggcgaaaaa tttattggtt
    11161 ttgtcggtca agtgcatcca acgattacaa aaagttatga tattccagaa acatatgttg
    11221 ctgagtttga tttatctgct atagtggaag ctgctcaaaa agggatcgtt ttcgaagcag
    11281 tgacaaaatt cccagcagtc agccgggaca tcgctttgct tgtaaaagaa actgtgacaa
    11341 atcaggaatt aacagaagtt atccgttctg ctgccggaag atttttaaca gatatccaat
    11401 tatttgatgt ctatcaagga gaaaacattg aaaaaggaca taaatccatg gcgtatagcc
    11461 tgacattcgt caacccagaa gcaacattga cagatgaaga aatcaataaa gcaatggaaa
    11521 aagtcgaaaa agcgttggta gaaaacctag aggcaagtat tcgctaagaa ggaaaatata
    11581 gtaagtaacg atcaagtagc ttttgaagac catacatttg aaaaaaagat gtgacacaac
    11641 ttcgtcacat ctcttttttt gattttaaaa aaggaatagc acagagacga gataaaaaaa
    11701 caggccttta cagcctgctt ttttagagta aatgaattaa tggaagtaat tgattcccat
    11761 tgctgatttt acttcagaaa gtgtttgtgc agctacttta gcagcttctt cactaccttt
    11821 acgtaagatt tccataacag ctgaaggatc tttttccaat tcttctcggc gcgcacggat
    11881 cggtgcaaat tcagcttcca atacatcaat gaggtatcgt ttgatcttta catcaccaag
    11941 tccgccgcgg cggtaatgag ctttcatttc ttcaattgct tctttatctg ttccgaatac
    12001 atccaagtag gtgaagacca tattcccttc tacttgtcca ggatcttgta catggatgtg
    12061 gtttggatca gtatacatac tcatgacttt tttctgtaag acatcggcag gatcggagat
    12121 ataaataccg tttcctaacg atttactcat tttgccattt ccatcgattc caggtaatct
    12181 acccattcct tttggtggga atacgccttt tggttccacc aagacttcac catatgtatg
    12241 attgaagctt tgtacgattt cctgtgtctg ctctagcatt ggtttttgat cctcaccaac
    12301 aggtacaaga ttcgctttga atgcagtgat atctgctgct tgagaaacag gatagataaa
    12361 gaatcctgta ggcacgcttt caccgaattt tttttgttcg atttctgttt tgacagtcgg
    12421 attgcgccga acgcgtccta cgctgactaa gttcaaataa tacatggtta attcagctaa
    12481 ttccggaatt tgtgattgga taaataaagt agattttgca ggatctaatc ccacggctaa
    12541 atagtctaaa gcaacttgca agacatttga tgaaaccttc tcaggatttt tagcattatc
    12601 tgtcagtgct tgcatgtcag caatcatgac aaacagttgg ttgtcttcat ctgcctgcat
    12661 agccactcgg gtttttagag aaccgacgta atgccctaaa tgcagcttcc cagttggtcg
    12721 atctcccgtt aaaataatat ttttcaaaaa agacacctct ttacgatttg taagtctgag
    12781 cacttaatat cttaccgttt ttcctgaaaa gaaacaacag ttcctaagga aaaaacaagg
    12841 aaagaggata aaataactaa tagattagaa atggaagaaa tatttatggg agaataaacg
    12901 ttctaagaaa ctttacaaat tactaaacta tcagatataa tgtattttat tatacatctt
    12961 taaaagaaat cttactaaat aataatggga gtgtaattct atggcaatga ttaaatttga
    13021 tcacgtggat aaatattatg gcaagttcca cgcattaaaa aatatcaatc tcgaattcga
    13081 gaaaggagaa gttgtcgttg tcattggtcc ttctggttca ggaaagagca cgatgcttcg
    13141 ctgtatcaat ggattagaga cgatctcttc aggtaagctg ctgattaatg atactgactt
    13201 gcatgataaa aagacaaaac tgacagaagt ccgaaaaaac atcggcatgg ttttccaaca
    13261 tttcaatttg tacccaaata aaactgttct ggaaaacatc aaattagcac caatcaaagt
    13321 gttgaagcaa gaccaggcaa ctgcagtcaa aaacgcggag aaatttttga aaactgtcaa
    13381 tatgttagat aagaaagatt cttatccttc catgttatcc gggggacaac agcaacgggt
    13441 ggcaatcgcc agaggtttag cgatgaatcc tgagatgctg ctgtttgatg aacctacttc
    13501 tgctttggat ccggaaatga ttggtgatgt attagacgtt atgaaaaaat tggctcatga
    13561 cggtatgtca atgattgtcg tgacacatga aatgggcttt gccaaagaag tggcggatcg
    13621 tgttatcttc atggctgatg gagaagtatt ggaagacagc agaaatgtga gagacttttt
    13681 cgaaaatcca aatgaagtcc gagcacagca atttatcagt aaagttatca atcattgata
    13741 ggaggaaaaa gatgcgcagg ttaaaaaaaa tacgcctgat tttcctttta ggcattgctt
    13801 ttcttgcact agccggatgt aaaggaaatg ggttggcaaa tgaagatatt ttagagcgaa
    13861 gcaaatctac caatgaaatc atctggggtg tcaagtatga tactcgatta tttggaatga
    13921 tggatattga gagcagaact gtacaaggat ttgatgtaga tattgcaaaa gcaatcacta
    13981 aaaagatcct tggtgacaat ggaaaaacag aatttgttga agtcacttct aaaactcgga
    14041 ttccattatt gaaaaacgga aatatcgatg caattattgc aacgatgacg atcacagatg
    14101 aacgaaaaaa acaggttgac ttttcagatg tctatttcga tgctggccaa gctttgttgg
    14161 taaagaaagg aagccaaatc aaaagtgtag atgatttgaa tgcttctaca acggttctag
    14221 cagtcaaagg ttctacatcg gctgcgaata tccgacagca tgcaccagat gcaaaaattt
    14281 tagaattaga aaactatgca gaagcattta ctgctttaca atctggtcag ggagacgcga
    14341 tgactacgga taatgcgatt ttgttaggga ttgcagatga aaatccagag tatgagttag
    14401 ttggtggaac gtttactaat gagccttacg ggattgcgat caacaaaggg caagaaaact
    14461 tcttgaaagc tgttaaccaa gcgctagagg aaatgcatgc agatggcaca tacgataaaa
    14521 tctatcaaaa atggtttcca aatgaaactg aaggaaaagt agagtaaggg ggagaggcaa
    14581 tgagcgaatt gatacaaact tatggaccaa tctttgtcga cgggttcaag atcacattgt
    14641 tttcgagtgt cttagcactt gtgtttagtt tgattatcgg aacgttaatg gcaatcttcc
    14701 aattatcaaa gaataaagta gtgagcgcct tagcaaaggc atatgtagaa ttttttagaa
    14761 acattccatt attaatcatc gtgatgtttt tttatgttgt cgtaccgatt tattggttta
    14821 atctagatgg attccaagca ggtacgattg gattaacgat ctatacatct gcttttattg
    14881 ctgaaacagt acgttcaggg attcaaaccg taccaaaagg tcaaacagaa gcaggactat
    14941 cttctggttt tacctattca gaaatcatgc gttatattgt tttaccgcaa gcattcaaaa
    15001 tcgttatccc gccattaggc aaccaattta tcaacctcgt aaaaaactca tctattttag
    15061 caatcgtagc tggtttagat ttgatgtatc aaggagactt gatcgctagt gaaacattca
    15121 ataccttcga tacgtatatc atcgttgggt tattttactt agttatcacg ctaccgttat
    15181 cttacttaat ggtttatctt gagaaaaaat gggcggttcg ttcatagaag gaggggaaat
    15241 acatggattt tagcggcgct ttttcatgga tgaatatccg ttttttattg gaaggattaa
    15301 aggttactgt tgaagtttca ttgttttcga tcatttttag tttcttgatc ggtggtctga
    15361 caggtgtgat tcgttttgcg aatatccctt tcttttccaa aatccttggt gtagtgattg
    15421 atattatacg gaatcttcca ttattattga tcattttctt cacttacttt gccttacctc
    15481 aaatcggcat tcagatgaac atcttctggt ccgctgtcgc agcattaacg atttttgagt
    15541 cagctatgtt gtcggaaatt ttccgagctg gactcaatgc tgttccaaaa ggacagatgg
    15601 aagcaggatt atcaacggga ctgacttatg tagaatcgat gcgaacgatc gtgttaccgc
    15661 aagcatttaa atcaatgatc ccggcaattg tgagccaatt gatttcactg atcaaagata
    15721 cttcattagc agtaatcatt tctttacctg aactttctca tcaggcacgt attatttatg
    15781 gacagaacac caattatgtg cttccgatgt tcatcatcat gacacttatg tacttcgtgg
    15841 tatgttacgc gctttctctg ctttccggtt acttggaaaa gagacggtac agttattaat
    15901 agatgattct tttagcggtt gtggcaaact aaagtcacaa ccgcttttcc tctttccatt
    15961 cgaaaaaaag agatttcgat tgttttaagc aagtaagagc acttgaaaat tcacgctaaa
    16021 aagtacacaa tagggaggat agaatttatt gaaaaaaagg atgatacgat tgacagataa
    16081 tcgccctatc ggatttattg attcaggtgt cggcggcttg actgtagtaa aagaagccct
    16141 gaaacaatta ccgaatgaaa atattttatt tgtaggagac acagcacgct gcccatatgg
    16201 ccctagaccc gcggaacagg taatccagta tacttgggaa atgacggatt atctggtgga
    16261 gcaaggaatc aagatgctgg tgatcgcctg caataccgca actgcggtgg ctttagaaga
    16321 aatcaaagct gctctttcta ttccagtcat cggtgtgatc cttcccggta ctagagcggc
    16381 agtaaaaaaa acacaaaata aacaagttgg cattatcggt acgattggta cggtaaaaag
    16441 tcaagcttat gaaaaagcac tgaaagagaa agtaccagaa ttgactgtga caagtcttgc
    16501 ttgtcccaaa tttgtttcag ttgtcgaaag taatgaatac cattcatcgg tggcgaaaaa
    16561 aattgtggca gaaacattag ctcctttaac cactaaaaaa atcgatacat tgattttggg
    16621 atgcacccat tatccattat tacgccccat cattcaaaat gtaatgggag aaaatgttca
    16681 actgatcgat tctggagcag aaacagtagg tgaagtatct atgctgttag attatttcaa
    16741 tttgagcaat tcaccgcaaa atggtcggac attatgccag ttttatacaa ctggctctgc
    16801 caaacttttc gaggaaatag ctgaagactg gcttggaatc ggacacttaa atgtagaaca
    16861 tatcgaattg ggaggaaaat aaggatgcgt catgacggga gaaaagccca agagcttcgc
    16921 aaactggagc ttcaaacaaa tgttttcaaa tatccagaag gatcggtagt gatccgtttt
    16981 ggtgatacaa cagttatttg ttctgcaaca atagaaaatt ctgttccccc ttttttgaga
    17041 gaaacaggaa caggatgggt gacagcagaa tatagtatgc tgcctcgagc aacgagtacg
    17101 agaaatcgta gagaaagcag caaagggaaa ctttctggta gaacaatgga aatccagcgt
    17161 cttattggtc gttccttgcg tgcagtagta gacttggaaa aattaggaga acgtagtatc
    17221 atcgtagact gcgatgtgat ccaagcggat ggcggtacta gaacagcaag tatcactggg
    17281 gcatttgtgg cattgaaatt agccattgaa aaacttttaa gagaaaaaga attgtcagaa
    17341 gatccaataa aagaacatct tgctgcagtt agcgtaggaa tcttaccaga tgggacttgc
    17401 gtcacagatt tggattacca agaagattcc gcagcacttg tagacatgaa tcttgtaatg
    17461 acagaatctg gaaaattcgt ggagattcaa ggaactggag aagaagcaac gtttgatggt
    17521 gaacagttga atgaaatgct cttttttgga aaaaacgcga ttgaagattt gatcaaagag
    17581 caaaaacatg ctttgctaac agagtttgct caaaatgatg agcggataga agaaacaaaa
    17641 acaatcatca ttgcgacaag aaatccagga aaagcagaag agtttcgaaa tatgttcaaa
    17701 gaagcgggat atcatgtaaa aacattactt gactatcctg aattgccaga tgtggaagaa
    17761 actggcagca catttgaaga aaatgcccga ttaaaagcag aaacgattgc acaattgctt
    17821 gatcagccag tcttagcaga tgattcaggt ttgaaagtgg atgctttagg cggtatgcca
    17881 ggaatctatt ctgcacgttt tgcaggggaa caaaaaagtg atgcggggaa taacgccaaa
    17941 ttattatatg aattgacaga tgtgccggat gaaaaaagaa cagcacaatt ccattgtacg
    18001 ttagtattcg cggcacccaa aaaagacagc cttgtagtag aagcggaatg gcccggtcga
    18061 gtagcccgta taccatctgg cgaaaatggc tttgggtatg atcctttatt tatcccagaa
    18121 ggtaagaaac aaacagcagc agaattatcg agcgaagaaa aaaacaagat cagtcatcgg
    18181 gctcaagcaa tgaaaaaatt gagtgccgag tggaaacaat ggctggaagg agagagatag
    18241 atgcggtatt tagtagtaag tgataatcat ggagacagag atatcctcgt tgacttagta
    18301 gatcgttatc gttctgaagt ggatatcttt ttccattgtg gtgattcgga attagaagct
    18361 tctgacccat tatgggatac attccaagtg gttcaaggta attgtgatta tggaccagga
    18421 ttcgaacaga aaaaagtgat ccaaactggt caggatacag tattcatgac tcacggtcat
    18481 ttatcgaatg tccgatttgg tttgacacag ttagcaatcg aagctcgagc tgcaactgcc
    18541 gatatggtgt tttttggtca tacccatcaa ataggctgtg agatggatca gaaaatcctg
    18601 tttttgaatc ctggtagcat ttctcagcct agaggcccga tccaaatccc atcatatgct
    18661 cttatcgaaa gtttagatga ccaaatttct gttcaatact ataaccgtgc ccatcaggca
    18721 gttgaagagt tggccttttc tttttcgaga gagcgctgaa taaaaaaact ctaattttta
    18781 ataaaaataa gctttatttt atgaattttg catccggttt cggtaaaata gtagtgttga
    18841 atgaaataga aatggaggcc atcagatgat tggacctata gtaagagaaa tgctgctgga
    18901 aaatcaggaa acgtttttga ttcctgcaga aaatgtggca aatgttatgt atcatcatcc
    18961 attgtcccat ggtttacttg tgttatcgaa ggtcggttat tccaaaattc ctgtattagg
    19021 aaaagatgat cactttgtag gactagtaag tttatcagat gtggtcaata aaatgattga
    19081 cttgcaaaca atcagcatgg acccgttaga aggactaacg gttgctgatg tgacagaaac
    19141 agatgttccg acaattgatg aaaattggga actagaagaa gtactccatt tgttagtcga
    19201 ttcgcctttt ttaccggttg tcacagaaga tcggattttc aaaggaatca ttacaagaaa
    19261 agagctgctt aaagccgtaa acttcatggt gcatgaatta gaacgtcgta atatattgtc
    19321 tccgaaaatc gaagaattaa aagaacaaat cgatatcgtg agctaaagaa cgagaaacta
    19381 aaagataatc aaaaaataag tagaaaaaac agcgtaccag ttttgacttt atcttgaaaa
    19441 agaggctggg acaaaagcgt ttaactccaa gaaataagaa ggaattcacg aaaattgctt
    19501 ttcaaatttt tgtgaatttc agcttatttc cgaaggagtt gcttctgctt ccgccgttta
    19561 tacgtgttta gagcgtggga caaaagtgtt ctttactttt gtcccacgct ctttttagtg
    19621 agattcgttg catcgtttgt ccaaattatt ttccgacagc aattggactg ttcggaatcg
    19681 tgaaaccaga agctgtcaat tctttgacat aggagctcaa gaactcttct tttaaggcat
    19741 attgttttcc gttcaatgcg tagcagaccg tacgaatcgc aaaattgctg tttccaagat
    19801 ccactaatcc aaagatagaa ggttcagttt ggagctcttc ttggtatttt tcagctaatg
    19861 tacgatttac tcgatcaatg atctcataga ttttgtcata tccttcttca ggaacaatcc
    19921 gaatatctaa aagtacttgc atatttgcac gagagagatt gctgatcgtg gtgatgtttc
    19981 gattcgggat gaaatggaca gtaccatccg ttgctttcag ctgaagggta cggataccaa
    20041 cagatacgac ggttccttca atcgttaagt ttgctagctt gatgtagtcc ccaacatcca
    20101 tctgttgttc catgataata aaaaatccgg taataacatc actcatgaac ccttgggcac
    20161 caagaccgat tgccacacct gcaattccgg caccagccaa aagtgatccg atcggcacac
    20221 cgatagcaga taaaattgca tagataaaaa agaaaccaag ggtataatga aaaatagtat
    20281 ttaaaagact atgtaaagtc tttaagcggc tctcgtttag aatggctttt ttagaatact
    20341 gattaaaaga cttatcaatc agatattttc ccacacggtg aagaatccaa aaaaggacga
    20401 tcaaaaaaat cagatataaa cttttttgga taaaggcagc caaaatggcg tcccaatcaa
    20461 tcccgtccca aaaccgctga aacgcattta ctttgctgac agcttgatct gtcaatgtct
    20521 cgccagaaga gtctgtcgta ccggcagttg ctaataatga aaacataaaa tcctcttttc
    20581 taaaatttga ttctttctgt attgtaccaa gaagttttca aaaaaggaaa tagcaaaaat
    20641 aactataatg aaggaaaaaa gctgaaaata aaatgacaaa taatatggat aatgataaaa
    20701 tgtggagaaa ataacgaagg tggtaagtat atgcaaatcg attggaacaa tctaggtttt
    20761 tcttatatca aaactccttg gcgttttatt gccaaatgga aagacggaca atgggaagaa
    20821 ggagaattga cagaagataa ttacctgacg attcatgaag gctctccagc gcttcattat
    20881 ggtcagcaat gttttgaagg tctaaaagct tatcgtcgaa aagacggcaa ggtcaatctc
    20941 tttcgacctg aacaaaatag tcgacggatg aatcaaagtg ctagacgatt gctgatgcca
    21001 atggtccctg aaaagatgtt cgttgatgct gtcaagcaag tggtaaaagc aaatgaagat
    21061 tttgtgccgc cctatggaac aggcgctaca ttatacttgc gccctttact gattggggtc
    21121 ggtgaaaaca ttggtgtcca tccagctcca gaatatttat ttgtcgtctt ctgtacgcca
    21181 gtaggagcgt atttcaaagg tggactaaaa ccaacgaatt ttattgtatc tgattacgat
    21241 cgtgctgctc ctaaggggac tggtgcagca aaagtcggcg gaaattacgc agcgagttta
    21301 cttccaggaa cagaagcaaa agaactggat tactcagatt gtgtttatct tgatccagcc
    21361 acacatacga aaatcgaaga agtaggtgca gcaaatttct ttggaattac aaaagacgga
    21421 aaattcatca ctccgcaatc gccctctatc ttaccaagta tcacgaaata ttccttgttg
    21481 cagttagctg aagaacgact aggactgcaa gcaattgaag gagatatttt cattgatgat
    21541 ctagatcaat ttgcagaagc tggtgcatgt ggtacagcgg ctgttatttc tccaatcggt
    21601 gggatttatc acaataacaa tcttcatgta ttttatagtg aaacggaagt aggaccagta
    21661 acaaaacggt tgtatgatga attgacaggt attcaatttg gagacataga agcaccagaa
    21721 ggctggattg aagtcgtgga ataatttcaa agtaatgagt tgaaaaaaac gtaaaaagaa
    21781 aaaatcagga agagacttta aaaagttttt tcctgatttt tatatgtttt actttaaaga
    21841 atgcaacaaa agtttatgaa agatggacac ctttgtcaac gtagataata tcaccgatga
    21901 ttccgctgga aagtgggctg attaagaaag cacaagcatt accgacttct tcgatcgtca
    21961 caccttgctg atcaggcgta cgagattcag ataactggat cagtttttga tagtctttaa
    22021 cacctgtgac agctaatgtt ttgattgccc cagctgagat tccattgacc cgaattcctt
    22081 taggcgagaa ctcagctgcc aaataacgga tagcagcttc aagagaagct ttcgcaatac
    22141 ccatcatgtt ataattcggg attgcgcgtt ctgaacctag ataagtcatg ctaacgatcc
    22201 cgctgtttgg tgcaagaaac ggttgtgcgt attttgatac agcaattaaa gagtagctgc
    22261 tgatatcttg agctaattga tagccgtctc tggaaatatc agacacattt ccggacaatt
    22321 cttctttgtt ggcgtaagca actgcatgga caaggccgtg gatctcccca gcatattcac
    22381 cgatggcatt cattgctttt tcgatgcttt cgtcgctaga aacatcacat tctacagtga
    22441 atgcttcttc gccgaccaat ttgactaatg attttttcat tcgttcattt tggtaagtat
    22501 agataatttc tgccccttgt ttcaacattg cttcagcaca accccaagca atgctttttt
    22561 tgttagcgac gcccataatg acgatttttt ttccttctag aaatgacata atgactctcc
    22621 tttgtttctg ataaaaattt gatagtcgta aaaaaataga gaataatagc taaaataact
    22681 tcttgatttc ttaattatta gtcaaaatgt tttgattgtc aaactatttt ttcttaaatt
    22741 aaaaaaagat tgctaaatat ttaggaatat gatactttga tagtcaaagt aatgaaaatg
    22801 gcaattgcct gaaagaagga gtttaattat gtcttacgta ttatctgcta ctgaagtaat
    22861 ggaattgatt cctaatcgtt atcctatttg ttatattgat tatgtagata ctttagaacc
    22921 aggaaaaaag atcgttgcga caaaaaatgt aacaatcaat gaagattttt tccaaggtca
    22981 ctttcctgac aatccagtga tgccgggtgc gttgattcta gaaacactgg cacaagcagg
    23041 ttcgatactt atcctaaaat cagaagagtt tctaggaaaa agagcttata tcggtgggat
    23101 caataaggcc aaattccgtc aaaaagttgt tccaggagat gtgctgaaat gtcattttga
    23161 aatcaccaaa atgaagggat cagtcggtac agcgttatct gcagcatatg tagatgataa
    23221 aaaagtctgt gagtgcgagt tcacgttcat cgtcaaccaa aatgcttgac tataaaacct
    23281 gatatagcaa aacaaaagga agcttacttg ctttttatgt aaaaagaaga cgcctgaatc
    23341 ctagcatacg ttgtcatcta tgcaggattc agacgttatt tttttatttt tgttttgctt
    23401 cttgcagtat attgatttta tcgattttta cttcttcttt tggtttgtct gaactatctg
    23461 tttcgatatt tgcaatagca tccacgacat ccattccttc aatcacttgg ccgaagacag
    23521 tataatggcc atctagtgaa ggataaccgc cgtttttata agcgtcgatg attgcttgag
    23581 gatagtcgtc ttttaaaaga ccatcatgca tatcatctgt attttgaacg ataaagaact
    23641 ggctgccgtt actgttagga tcttgtgagc gagccataga taacgcacct cttatattat
    23701 aaaggtggtt gttgatctct gtttcaaatc cttctcccca aatgctttcc cctccagtgc
    23761 catcgccttt aggatcgcca ccttggatca tgaaatcttt gatgacgcga tggaaagtca
    23821 gtccgttgta gtaaccgtct tttgcatgtg tcataaagtt ttcaaccgct tttggtgcgt
    23881 gttcgggaaa taatttgatt ttgattgtgc ctttattcgt caccatttcg accagatctt
    23941 cattttcggc gacatctttc gtcaattgtg gtaattccaa tgcgttcaaa tcgacgctac
    24001 tggcagtcgt gctttccgca gtagatgtac tttttgaact ttctgtagac gaactagaag
    24061 aagtcgtgtt gtttgcagaa caaccagcag caaacagcaa tgctgctgct aaactaatac
    24121 ttaaaataac tttatttttc ttcataactg ttcctttcca atttactatt ttgttatctt
    24181 taatgataac aaaatagagg gaaaatacct acttaaatta ttggaattta tcatttattt
    24241 taaaagaaaa agaaaaggtg tagaccattt actttgtgtt tgctataatg taagtggata
    24301 caaaaacgaa aagatgcagg aggaaatggt aatatgggaa aattaggaat ctcgatttat
    24361 ccagaacggt caacatttga aaaggacaaa gcgtacttgg atttagctca taagtatggg
    24421 tataaacggg tttttaccag tttgctgcag atcaatgatg ataaagaaaa agttctttca
    24481 gaatttaaag aagtagttga ttacgcgaat agcctaggca tggaagtaat ggttgatatc
    24541 aatccagcgt tatttgaaca gttggagatt tcttacgatg acttatcttt tttccataag
    24601 atgggtgcct acggggtccg cttagatatc ggattcacag gagcagaaga agcaaaaatg
    24661 acgcgcaatc cttttggtat caaaatcgag atcaatatga gttcgggcac gaattacgtt
    24721 gacaacatca tgagttattc gccaaacacg gataatttat taggttctca taatttttat
    24781 cctcatcgat actctggttt aggatacgaa cactttgttt tttgttcaga aaaattcaga
    24841 aaatataatt tgaatacgat ggcattcgtc aattcgcaat ctgctgagtt tggcccttgg
    24901 cctacgcaag atggcttgtg cacgctggaa gaccaccgag atcttgaaat tgcgacacaa
    24961 gtgaagcatt taatccttac aggattgatt gatgatattt ctattggaaa tgcgtacgca
    25021 agtgaagaag aattgaaaga aatggcagaa gcatttaacg cggattatcc aacattgaaa
    25081 gtagatacgg aagaaggtat tacagaaaac gaacgaatct gcttgtttga taaccttcat
    25141 agttatcgag gggatcgctc agaatatatc cttcgttcaa cgatgactcg tgtatactac
    25201 aaagataaag atttcccgcc tcataatacg cgagatatgc atcatgggga tgtactgatt
    25261 gacaatgaag ggtacggtca atacaaagga gaaacacaaa tcgccttgaa ggatatgaaa
    25321 aacgacggac gtgtcaatgt tgtaggaaga atctccgatg acgaattatt cctccttgac
    25381 tttttgaaac catggtcaag ctttaaatta attgaaaata aaaaatagat aattagttat
    25441 tgcagaaata atccgctaga aatagccagt tatttctgct tttttatttt gtttttttat
    25501 aggttatgat ttgtcaaatt aagctagaat aaaatgcttc ttgtacatag ctcaaaaata
    25561 tttcgattgg tgttctgtaa ttcaatgatt ttcttggaat atgattacgt tgattgctga
    25621 cactggaaat aaatgtctga ttcacttttc taaaatccat tgatttcggc agtccattac
    25681 gacgcagaat cccgttagaa ttctcgttta atgggcgttg agaaggtgtt ccagggtccg
    25741 caaaatatat atcaatatca tgttggttac taatggcttt ccagttagaa aattcttttc
    25801 cacagtcaaa cgtaatagat ttaaagaagt ttttagggaa gcgagaaaac cattgattaa
    25861 gggcagtttc aatatctaat gccttacggc cgttgggttt aatcgtgata atgactttag
    25921 ataatctttc aactaaagta atgacggcac ttttatgatg aatgccaacg atcgtatcac
    25981 cttcaaggtg accaaactca gaattgaaat caggataatt atcaggtcga tcatggattg
    26041 agcgctgata ctgttgtttt ccccgttttt cctgatggcc attgggtttt cttttacctt
    26101 tcatcggtag tgtgtcaata tcaaatattc ctttagaaaa taaacgataa agtgttctca
    26161 taccgcatga aacagacctt tcttttcgcc cgataatgac gtcaggcgtc caaccaagag
    26221 tgactttctc tttaatgtaa tctacttcat gagcaggtaa ttgaatgact tttctaccac
    26281 attttttctt attttcttta tactggtgcc aataatcaag agcagtcttg ccttgcttga
    26341 acttattgac tacattataa atagtttgta tagcacgtcc cattcggtta gcgatttcaa
    26401 ccggcttatt atgttgaaga taatatgatt ctatcattgt cagttcgtct atggtaagat
    26461 gtttgtaggt catttatggg ttacactcct ttgttttctt tcgtcggaaa tacaatttga
    26521 gtgtaccata aatgcctttt tatttttcta acttaatttt acaattcgcg attatttaaa
    26581 actcagcctt tttttgctta attcaaattg aatcagatta tattctagtt aattaattcc
    26641 ctttaattaa tgtgtttctc atcatggtaa tttcagcatt tccacatctt caacatcatc
    26701 aaactgttaa ttgtaaatta ccatttttcg gatcatatgg ggatacatta aaactatacg
    26761 cttttttgaa gtcgcgactg tcgggatttg aggattgaat tagaagcgag tatacttcgg
    26821 ttcacataat tatattatcg ttgtttgaaa taagtgtatt tttccatccc atcacaagga
    26881 cgtacttttc atatattttt ttctccgctt agcattctaa tatattaatt tccaatgccc
    26941 tttttatatt cttccactgg caaaacaaaa aattctaacc ttatcctttt cgaatagtta
    27001 cttttaactc tagaatatgc caatattctt atgcctagta ttaattgtat gataattttt
    27061 ctgtactact acactatatc gattccaata tccactcaat aaactctatc acagattcgt
    27121 caccaccact gtgagttaca ataaaatcag ataattcaat ctcatttctt gtggcatttt
    27181 ttggacattc tactattcct cccgcttctt cacagatgtc atacatgata aatcattaat
    27241 atcatcacca atataagcaa cttctgaaaa attcgatgta atgaaaagta acttgttaat
    27301 cacaccttga tgaactcttt taatccattt tcataacaat gatttaagac aatacttgag
    27361 gttcttccat taataatcac aggttctgcc cctggaaact tttgtagata cataaaaata
    27421 aaaaagtagc caagaaacac tcatagctta tgaatgtttt tgactcctat tagtactttg
    27481 ctcaataccg atttatcagt agttataata tttttcttta tttcatatgc tgttaggctt
    27541 ccgtcctttt ttcgccttac ttctgcatta tttcctcttc tgttatctcc aaaacagtaa
    27601 gctatgaatt ttgcgcctgt aacatcgttt gcttatcctc tattggttca gccctacgta
    27661 tatcgtacat tacctctttt cactttataa aattaaactc ttctactctc atccggtctt
    27721 tccaagcaat aacctaacga atcatcactc aaacataaag agaagtgaac tgttgataag
    27781 aatttgataa accattccga agtaccaaag caatactgtt tgtcacctag ctgttttcga
    27841 actcctactt tactgaatct cacgcgaata tctgatttca tcacaccaat tagctctgta
    27901 tttataccat acctaccgag catttgttcg ccaatcgttt ttcaaattct ctttttcaca
    27961 aaacaagtta atactttctt aattgtcaaa ttaaattaga cagatcatca atacttacgt
    28021 aactcaaaaa tacttccaaa ggtgttcgat aatcgttcga taatccagtg attttctagg
    28081 aatattattt cgtttagatg cgacagattg aataaaaaat tcatctactg aattgaaatc
    28141 catagatttc aataaaccat ctctacgtaa caatccgtta gaattctcgt ttaggcctct
    28201 ttgagacggc gttcctggat cagcgaaata aatggcaata tcattgacat tactgatctg
    28261 tttccaattt gaaaattcct ttccacaatc aaaagtgatg gatttgaata ggtttttcgg
    28321 tacagattca aaccattgat ttaatttttt ttcaatatca atcgcttgtc taccacacgg
    28381 tttcaatgtg atgataactt ttgataatcg ttcaactaag gtaattacag cacttttatg
    28441 tttcagacct acgatagtgt caccttcaag gtgaccaaac tcatttgaga attggctata
    28501 atccttttca cgttcatgaa tagagcggcg gaaagtttgt tttccacgtc tttcttgatg
    28561 tccattcggt ttacgcttgc ctttcatcgg taagtcagaa gaatcaaata gccccttttt
    28621 gaacatacga taaatggtac gagcagaaca actaatagga aacgctgcac gaccaacaat
    28681 cacatcgggt gtccatcctt gaacaacctt tctttgaata tattctgatt gttcctcggg
    28741 taaaacaagc ggacgtctac cacagtttga ttt
//
LOCUS       DACGEU010000031        28001 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.031, whole genome shotgun sequence.
ACCESSION   DACGEU010000031 DACGEU010000000
VERSION     DACGEU010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 28001)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28001)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28001
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.031"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(1..381)
                     /locus_tag="IXR40_001249"
     CDS             complement(1..381)
                     /locus_tag="IXR40_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HAQ4361110.1"
                     /translation="MAVKKQCNHAGCKTLIDYRQKYCGKHKAKQTAIKREERKQSEGK
                     YFQFYQSRTWRKASYLYRLNHPVCEDCLEEGLIRKADVVDHKIELKDDWNRRLDETNF
                     RSLCHAHHNSKTANERQRREKSTL"
     gene            complement(385..600)
                     /locus_tag="IXR40_001250"
     CDS             complement(385..600)
                     /locus_tag="IXR40_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361111.1"
                     /translation="MHMESIRYFDGEKHIEYSNTQEDVDFISFEEDKITKVNFKDGTC
                     LKIVSPYIEYKSKWEQDDSDERDRFGW"
     gene            complement(603..1010)
                     /locus_tag="IXR40_001251"
     CDS             complement(603..1010)
                     /locus_tag="IXR40_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3206 domain-containing protein"
                     /protein_id="HAQ4361112.1"
                     /translation="MLNIISTNKAPNFQYTDEMDRFLMNTLAFSVGLVTEDYSTFDPE
                     VLKIMEEEPDWLQESVAWCQSLVVGSLVDSGNYDDTGELMDEFNCLLNLYDRARQREL
                     TSNEDNLFLNIHDKFLALLLTDDELITNLLEVE"
     gene            complement(1276..2751)
                     /locus_tag="IXR40_001252"
     CDS             complement(1276..2751)
                     /locus_tag="IXR40_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HAQ4361113.1"
                     /translation="MAHKHKLDSILDFPEASEREDNIIELKTWMSRLRCNKDDQIKSN
                     SVVNAELILTNDSNLAGTIAYNEFSGYIHLLKDSPWINRTAGEWEDSFEDALTAYIEE
                     NYNVVFDDNKIHKAVVNVARKNVFNPVKERIEKVKWDQQPRLETLFIDLLGVDDNLYT
                     REVTKRWIVGSVARIYKPGIKFEIVPVLDGPQGIGKSTVPALLYTDDFFTDSLDSLGE
                     KKDDYMQLQGNVIIELGELSSMNKTKIEQIKNFISAKIDKIRPPYGRNVIAWARQCVF
                     IGTSNDGQYLKDDTGNRRFYPLPCKNKPKMNPFKTKDEYFLQVLAEAKVLFDKGQRIY
                     FSPDEDKEVLEIAKDYQEDAKMENPIKEAITKYLEMEIPYKWEEAPAWARRSYYQNYP
                     DSKCNEKNLQHFYNGATMQQEFYLVDSVLTADILEAVFDKQAKDLLNGRSDAETKKIA
                     LIISSIPGWERKQLPKRNKRRGFYNKSNAYENKNRAGKYKK"
     gene            complement(2741..3589)
                     /locus_tag="IXR40_001253"
     CDS             complement(2741..3589)
                     /locus_tag="IXR40_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication protein"
                     /protein_id="HAQ4361114.1"
                     /translation="MANNYQAATELQKSGWSIYPLSPGTKIPIKGSSGWNDATNDSNQ
                     INEWWTEDATRNIGLMLEDHQMVVVDLDQHSETRNGVENYKKLASMYDPFPSTYTEIT
                     PGKGIHFFFKIPDGVIIQQETGAFADIFGRDDKGKSLSGIDIITKGVPIAPTMIISRS
                     VGRAYEPIENVSLNNIAPAPDWLVNLLLKKPQEIKTQYRPVAKTGTAKKLDMIVQGAG
                     EGSRNDHLTKLCGWLLWHGVDNQTLAELIYTANAYNEPPLKDKEVNQIIRSMIKKDLR
                     GKAHGS"
     gene            complement(3626..3988)
                     /locus_tag="IXR40_001254"
     CDS             complement(3626..3988)
                     /locus_tag="IXR40_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361115.1"
                     /translation="MYKTKLLNQLDSLELEEINQGIAELENNIGKTYFGNSFNEKLTV
                     LYVLKKHAEHKIICREINELKNQILTAWLNITDMQEARVKTFNTWVKYQNQLKGAEFV
                     RDGLKYELEQLKLMEVSE"
     gene            complement(4288..4912)
                     /locus_tag="IXR40_001255"
                     /pseudo
     CDS             complement(4288..4912)
                     /locus_tag="IXR40_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350005.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein"
     gene            complement(4909..5220)
                     /locus_tag="IXR40_001256"
     CDS             complement(4909..5220)
                     /locus_tag="IXR40_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361116.1"
                     /translation="MESTQNKAIEKVLSTILTEDTAAELANLEGKALEETFECLYEQM
                     DYQKLLPQEPTVSGVLRGLNDLVQAEFKERLSIEEYQEILYQQVELLASLLGLELEDV
                     E"
     gene            complement(5264..5557)
                     /locus_tag="IXR40_001257"
     CDS             complement(5264..5557)
                     /locus_tag="IXR40_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361117.1"
                     /translation="MELKIDKLTLDDPAFKIIDDRVVQQVEQTQGTLLSLLEKKYQFP
                     KYMNKAQAAKYMNVSYNTMMQKYVPNGLKLIIVDGVVRISQDECDRFMEEYQK"
     gene            5751..6398
                     /locus_tag="IXR40_001258"
     CDS             5751..6398
                     /locus_tag="IXR40_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4361118.1"
                     /translation="MNGGENVARKKYPEAVETGQRIRLARIEKGLSMEQLGGKLSPPA
                     SKGAVSNWENGYNLPNNTRLKQLSKVLDVSTTYLLNGSYTLRDMHMMPEIKRNVLEKQ
                     LKKTIEKNNSIIDSNLSNAINNIEEDNLTVSQKIYLTNAIKYLKTGSRIEFPDGSTPI
                     AYLAALLNTLLRYDSLINDSEKNTDEKKEYQEFYENDLLKEFTALVTELNKHYSK"
     gene            6459..7604
                     /locus_tag="IXR40_001259"
     CDS             6459..7604
                     /locus_tag="IXR40_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAQ4361119.1"
                     /translation="MATFKQYETKKGKFWLYEAYLGMNKMTGKPDKVRRRGYKTKKEA
                     QLALSRLQVDYDKNGIKKANNETFKEVYDLWLETYKTTVREATFMKTEIKFRKWILPK
                     YGNLRVNEVTVKKAQQIVNSWAETTDQYKVLHSTSKRIFSYAINLGIIETNPLDNVLM
                     PKRTTTKHKEKVKVYSKEQLITLFDYLNSKPETYRNDFDKTLLRFLFYSGVRISEALA
                     LNWSDIDFQENTVTINKTLSQSKNGYKISDPKTDCSAGVLPLDERTISILKKWQINQR
                     KYMLTLGVTDPTMIFCGIYKELITHHAIYARLITICEKAMVPFLGVHVARHTHASMLL
                     DAGATMVEVQTRLRHTKISQTIDCYGHLAKETKEKTVEKLVQHLNID"
     gene            complement(7685..7990)
                     /locus_tag="IXR40_001260"
     CDS             complement(7685..7990)
                     /locus_tag="IXR40_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HAQ4361120.1"
                     /translation="MTEHNHSHDHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEEE"
     gene            complement(8015..8446)
                     /gene="ruvX"
                     /locus_tag="IXR40_001261"
     CDS             complement(8015..8446)
                     /gene="ruvX"
                     /locus_tag="IXR40_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HAQ4361121.1"
                     /translation="MRVMGLDVGSKTVGVAISDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            complement(8443..8709)
                     /locus_tag="IXR40_001262"
     CDS             complement(8443..8709)
                     /locus_tag="IXR40_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HAQ4361122.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPSYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            complement(8964..9689)
                     /locus_tag="IXR40_001263"
     CDS             complement(8964..9689)
                     /locus_tag="IXR40_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HAQ4361123.1"
                     /translation="MSKKTTKAIVGIVAAVIAGAFGVSTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            complement(10050..10120)
                     /locus_tag="IXR40_001264"
     tRNA            complement(10050..10120)
                     /locus_tag="IXR40_001264"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10086..10088),aa:Gly,seq:ccc)
     gene            10237..10989
                     /locus_tag="IXR40_001265"
     CDS             10237..10989
                     /locus_tag="IXR40_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HAQ4361124.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            11005..11484
                     /locus_tag="IXR40_001266"
     CDS             11005..11484
                     /locus_tag="IXR40_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter"
                     /protein_id="HAQ4361125.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(11735..13315)
                     /locus_tag="IXR40_001267"
     CDS             complement(11735..13315)
                     /locus_tag="IXR40_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HAQ4361126.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(13308..14051)
                     /locus_tag="IXR40_001268"
     CDS             complement(13308..14051)
                     /locus_tag="IXR40_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4361127.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            complement(14227..15003)
                     /locus_tag="IXR40_001269"
     CDS             complement(14227..15003)
                     /locus_tag="IXR40_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4361128.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            complement(15251..16087)
                     /locus_tag="IXR40_001270"
     CDS             complement(15251..16087)
                     /locus_tag="IXR40_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HAQ4361129.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            complement(16098..17027)
                     /locus_tag="IXR40_001271"
     CDS             complement(16098..17027)
                     /locus_tag="IXR40_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HAQ4361130.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            17219..17572
                     /locus_tag="IXR40_001272"
     CDS             17219..17572
                     /locus_tag="IXR40_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HAQ4361131.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            complement(17646..18302)
                     /locus_tag="IXR40_001273"
     CDS             complement(17646..18302)
                     /locus_tag="IXR40_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HAQ4361132.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            18528..20462
                     /locus_tag="IXR40_001274"
     CDS             18528..20462
                     /locus_tag="IXR40_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAQ4361133.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            complement(20548..21771)
                     /locus_tag="IXR40_001275"
     CDS             complement(20548..21771)
                     /locus_tag="IXR40_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronyl hydrolase"
                     /protein_id="HAQ4361134.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(21765..23663)
                     /locus_tag="IXR40_001276"
     CDS             complement(21765..23663)
                     /locus_tag="IXR40_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HAQ4361135.1"
                     /translation="MVVKRGENTMKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQ
                     IDYIHQGVGYGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYW
                     GEIHERDQRMVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQF
                     FKIIVGTIIQKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYG
                     LIYSVLEPEKPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAML
                     WADLLPFKLGEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLW
                     LNKIFLLLALPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPN
                     FHTLTNEKYLKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKT
                     YGQFIVRNNVRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLY
                     ETGFAIECSPEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLM
                     TWENTFIPGLEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKN
                     NKKRLKLC"
     gene            complement(23657..24775)
                     /locus_tag="IXR40_001277"
     CDS             complement(23657..24775)
                     /locus_tag="IXR40_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 88"
                     /protein_id="HAQ4361136.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            complement(24858..25691)
                     /locus_tag="IXR40_001278"
     CDS             complement(24858..25691)
                     /locus_tag="IXR40_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAQ4361137.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVLATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            complement(25684..26601)
                     /locus_tag="IXR40_001279"
     CDS             complement(25684..26601)
                     /locus_tag="IXR40_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAQ4361138.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            complement(26828..27952)
                     /locus_tag="IXR40_001280"
     CDS             complement(26828..27952)
                     /locus_tag="IXR40_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAQ4361139.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
BASE COUNT         8560 a         5600 c         4597 g         9244 t
ORIGIN      
        1 tcaaagggta ctcttttctc gtctttgtct ttcattggct gtcttggaat tatggtgtgc
       61 atggcataaa gaacgaaaat tagtttcatc taaccgtcta ttccaatcat cttttagttc
      121 aattttgtga tctacaacat cagctttcct tatcaagcct tcttctaggc aatcctcaca
      181 tactggatga tttaaccgat acaagtatga agcctttcgc catgttctac tttgatagaa
      241 ttgaaaatat ttaccttcgc tttgctttct ttcttcacgc ttaattgccg tttgctttgc
      301 tttatgcttc ccacaatact tctgcctata atcaatcaat gttttacatc cagcatgatt
      361 acattgtttt ttaactgcca tagattacca accaaagcga tctcgttcgt cagaatcatc
      421 ttgttcccat tttgatttgt attcaatata aggcgaaact atcttcaagc acgttccgtc
      481 tttaaaatta actttagtga ttttatcttc ctcaaaacta ataaagtcta catcttcttg
      541 agtgtttgaa tactcaatgt gtttctcacc atcgaagtat ctaatacttt ccatatgcat
      601 aattattcta cctccaataa attagttatc aattcatcat ctgttagtag caaagccaag
      661 aacttatcat ggatgtttaa aaacaaatta tcctcattcg atgtaagctc tcgttgtctc
      721 gctcgatcat ataggttaag cagacaatta aattcatcca ttagctcacc tgtatcatca
      781 tagttgccac tatctaccaa tgatcccact actagcgatt gacaccacgc tactgactcc
      841 tgcagccaat caggttcttc ttccattatc tttaatactt ctggatcaaa tgtggaataa
      901 tcttctgtta ccaatcccac actaaatgcc agcgtgttca ttagaaaccg atccatttca
      961 tctgtatatt gaaagttcgg tgctttgttt gttgaaataa tattgagcat ttactttcct
     1021 ccttgattcg taacacgtgg taacacctac gtaacaggta cccgttacca ctcaatccca
     1081 acggggacaa gggttctagc gttttggtaa caggtaacgg gtaaaatcca gtaacattat
     1141 tccccagcat attagctaac tatttcaaaa gttttaagga aataaggtgt taccccgtta
     1201 ccaaattgct gtatcccttg gggcagtaag ggtaaactag taacgggcta ggtgttactg
     1261 acccgttact acccgttact ttttgtactt tccagctcga tttttatttt cataggcatt
     1321 tgacttattg taaaatcctc gtcgtttatt tctttttggc agttgcttcc gttcccaacc
     1381 aggaatactg ctaataatca aggcaatctt tttagtttct gcatctgatc gaccattcaa
     1441 taaatccttt gcttgtttat caaaaacagc ttccaaaata tcagcggtga gtacgctatc
     1501 aactaaataa aactcttgtt gcatagtagc tccattatag aaatgctgta aatttttctc
     1561 attacattta ctgtcaggat agttctgata ataagaacgt ctcgcccacg ctggagcttc
     1621 ttcccattta tacgggattt ccatttccaa atatttagtg attgcttctt taattggatt
     1681 ctccatcttg gcatcctctt gatagtcttt tgcaatttct aagacttctt tatcttcatc
     1741 gggactaaaa tagattcgtt gtcctttatc aaaaagcacc tttgcttcag ctaacacttg
     1801 aagaaaatat tcatcctttg ttttaaacgg attcatcttt ggcttattct tacaaggcaa
     1861 aggataaaaa cggcggtttc ctgtatcatc tttcaaatac tgcccatcat tcgacgttcc
     1921 aataaataca cattgccttg cccaagctat gacattccga ccataaggag gtctaatttt
     1981 atcgatcttg gcactgatga agttttttat ctgttcaatt ttagttttgt tcattgaaga
     2041 taattctcca agttcaataa ttacattgcc ttgaagctgc atataatcat ctttcttttc
     2101 acctagcgaa tctaatgaat cggtgaaaaa atcatccgtg taaagtaatg ctggaacggt
     2161 actcttacca atcccttgcg gtccatccaa aactggaacg atctcaaact ttattcctgg
     2221 tttatagata cgtgcgactg atccgactat ccaacgtttt gttacttctc gtgtgtaaag
     2281 gttgtcgtct acccctaaaa ggtcaataaa cagtgtttcc agtctaggct gttgatccca
     2341 tttaactttt tcgatacgtt cttttactgg gttgaaaaca ttctttctag ccacatttac
     2401 tactgctttg tgtattttgt tgtcatcaaa aactacattg tagttttctt caatatatgc
     2461 cgttaaggca tcctcaaaac tgtcttccca ttctccagcg gtacgattga tccaaggaga
     2521 atcttttaat aggtgaatgt atccgctaaa ttcgttataa gcaattgttc cagctaaatt
     2581 gctatcattg gttaaaatca attctgcatt cacaacactg ttacttttaa tctgatcgtc
     2641 tttattgcat cttaatcgtg acatccaggt tttcaattca atgatattgt cttcacgctc
     2701 gctggcttcg ggaaagtcta aaatactatc taatttatgc ttatgagcca tgagctttcc
     2761 ccctcaaatc ttttttaatc atcgatcgaa taatttgatt cacttcttta tcttttagcg
     2821 gtggttcatt gtacgcattt gctgtataaa tcaattctgc taaagtttga ttatctacac
     2881 cgtgccatag taaccaaccg cataacttag ttaaatgatc gtttctacta ccttcgccag
     2941 cgccttgaac aatcatatct aatttttttg ctgtccctgt ttttgctacg ggtcggtatt
     3001 gagtctttat ttcttgcggt ttttttagca gtaggttcac tagccaatcg ggagctggtg
     3061 caatattatt tagagatacg ttttcaatag gttcatatgc tctcccaaca cttcttgaaa
     3121 taatcatagt tggcgctatt ggaactcctt tagtgataat atcaatcccg cttaaacttt
     3181 tacctttatc atcacgcccg aagatatcag caaatgcacc tgtttcttgt tggataatta
     3241 caccatcagg aattttaaag aagaaatgga ttcctttacc tggtgtgatt tccgtataag
     3301 tagaaggaaa tggatcatac attgaagcaa gttttttata attctcaacg ccgtttcgtg
     3361 tttcagaatg ttgatctagg tcaactacca ccatttgatg atcttcaagc attaacccaa
     3421 tatttctagt tgcatcttcc gtccaccatt cattaatttg attagaatcg ttagttgcat
     3481 cattccaacc actagagcct tttattggaa ttttagttcc aggagataag ggataaattg
     3541 accatcccga cttttgtaat tccgttgctg cttgataatt atttgccaat aaacctctcc
     3601 tcctttttca aaatactggt ataaatcatt cagacacctc catgagcttc aactgctcaa
     3661 gttcgtattt caacccatcc cgaacaaatt cagcaccttt taattgattc tgatacttta
     3721 cccatgtatt aaatgttttc acccttgctt cttgcatatc agtaatgttt aaccatgcgg
     3781 ttaaaatctg attttttagc tcgttgattt ctcgacaaat tattttgtgt tctgcatgtt
     3841 ttttgagtac atacaaaact gttagttttt cattgaatga atttccaaag taggttttcc
     3901 cgatattatt ttctagttca gcgatccctt gattaatttc ctctaattca aggctatcga
     3961 gttggtttaa tagttttgtt ttgtacatct acttatgccc tccagttctt aattgatagt
     4021 cgtactcgtc ataagcagtg aagagatata acgctaatcc tgcaaagata gctatttttg
     4081 caattaatgg taataagccg aaaattccgc cgattaaaat gcttcctata attaagtttc
     4141 gtttcataat ggttccctcc gattttttaa tatggtataa tcggaacaaa gaatatcggg
     4201 ttttatccca attaagttgc ctttatcctg tccgccaaga ctgttatgga taaggctttt
     4261 tctttgttct cgatcatgtt aatgctccta agttgtctgc aattcagcag aacgattata
     4321 aattttctca ctcactgaaa actgcaaccc atatttttct ttaacagtca ttaattctac
     4381 tgtctcatct aaaataggtt cacgatcaac caacatttca ggagtcatat ctttcttttt
     4441 taccattttg gaatgaccat aaatagttga tacagcttta ttggctatca cattcgcttt
     4501 aatgtagtct actggttttg gttcagtaat agcgtggctt aatttagtca ttgcttcttt
     4561 ttggtgttct ttgtctagca tgcggaatac ttgaaagcct tcaagtcctg tggactggcg
     4621 tagttctttg atgatgtcga aaatccagtc ttgaaatgcc tcggcttctt ttttacggct
     4681 tttgaatgcc atgcggtaaa tatttttttt cgttgatgat gtttacatct tgtgttctgc
     4741 ccaatgaatc gatgacctta ctagtagtaa ccccatcttt aggcaaagag tgaatggctc
     4801 tagtaacctg tttaagacct aacgcttccg caacatcttt cgccactgcc caccattcat
     4861 cattaatatc gacaaatctt ataatgtgtc cgttccaaat ttcagttttc attcaacgtc
     4921 ctccagttca agccctagca agctcgctaa caactcaact tgctgataca aaatttcttg
     4981 atactcttca atagaaagtc gttctttaaa ctctgcttgt actaaatcgt tcaagccacg
     5041 caatactccg cttaccgttg gttcttgtgg tagcaatttt tgatagtcca tttgttcgta
     5101 caaacattca aacgtttctt ctagcgcttt gccttccaag tttgctaatt ctgccgctgt
     5161 gtcttctgta agaattgttg ataatacttt ttcgattgct ttattttgtg tcgattccat
     5221 tattatttcc tcctattaat ccctttgccc ccacggcttg cgtttatttt tggtattctt
     5281 ccataaagcg atcacattca tcttgtgaaa ttcttacgac tccatcaact ataatcaact
     5341 ttaaaccgtt aggaacatat ttctgcatca tagtattgta tgaaacgttc atatacttag
     5401 cagcttgtgc cttgttcata tattttggaa actggtactt tttttctaat aatgaaagta
     5461 acgttccttg agtttgctct acttgttgaa caactcgatc gtcaataatt ttaaaagctg
     5521 gatcatcaag cgtgagtttg tcaattttta attccatatt tatcccccct cgttagcata
     5581 catttctata caaagatttt aaaaaaatgc aagaggctct tgaatacatt tctatacctc
     5641 ttataaactc aatataccat catacctttt catttgcaag aattttaaca tacttttttg
     5701 aacttttatg tttcacacat atttaaatcg tgatatagta gagaaaatat atgaatggtg
     5761 gtgaaaatgt ggctagaaaa aaataccccg aagcagtgga gacaggacaa agaattagac
     5821 tggctagaat tgaaaaggga ctctcaatgg aacaacttgg aggtaaatta tccccaccgg
     5881 ccagtaaagg tgccgttagt aattgggaaa atggctataa tcttcccaat aacaccaggc
     5941 ttaaacaact ttcaaaggta ttagatgtat ccactaccta tctattaaac ggatcttata
     6001 cattaagaga tatgcatatg atgcccgaaa ttaagcgaaa tgtgcttgaa aagcaattga
     6061 aaaaaactat tgaaaaaaat aactctataa ttgattctaa tctttctaat gctatcaata
     6121 acatcgaaga agataacctg actgtctcac agaagattta tttaacaaac gcaataaaat
     6181 atcttaaaac aggatctcga attgaatttc ctgacgggag taccccaatt gcttatctcg
     6241 cagctcttct aaatacgctt ttacgatatg actcattaat taatgattca gaaaaaaata
     6301 cagatgagaa aaaagagtat caagaatttt atgaaaatga tcttctaaaa gagttcacag
     6361 ctcttgttac tgagctaaat aaacactatt caaaataata ataaactgcc tcctccaacc
     6421 gcccccacgg cttgctacac tatggaggga aaactattat ggcaacattc aagcaatatg
     6481 aaactaaaaa aggtaaattt tggctctatg aagcctatct tggaatgaac aaaatgactg
     6541 gcaaacctga taaggttcgt agacgaggtt acaaaacaaa aaaagaagcc cagcttgcct
     6601 tgtcacgctt gcaagtggac tacgataaaa acggtattaa aaaagcgaac aacgaaacgt
     6661 ttaaagaagt ttatgacttg tggctagaaa catataaaac cactgtccga gaagccacct
     6721 tcatgaaaac tgaaatcaag tttagaaagt ggattcttcc aaaatatgga aatcttcgtg
     6781 tgaatgaagt cacggtaaaa aaagcccaac aaattgtaaa tagctgggct gaaactactg
     6841 accaatacaa ggtacttcat tcaacttcta agcgtatttt tagctacgct atcaatcttg
     6901 ggattattga gactaatcca ctagacaacg tattaatgcc taaaagaacc accactaagc
     6961 ataaagaaaa ggtcaaagtt tacagtaaag aacaactgat caccttgttt gattacctaa
     7021 acagcaaacc tgaaacttat cgaaacgact ttgataaaac gttactacgc tttctctttt
     7081 atagcggggt taggatcagt gaagcccttg cattgaattg gtcagacatt gattttcaag
     7141 aaaatacggt caccatcaat aaaacactaa gccaatccaa aaatggctat aaaatcagtg
     7201 atcctaaaac tgattgtagt gctggggttc ttccactaga tgaaagaaca atttctatat
     7261 taaaaaaatg gcagattaat cagcggaaat atatgctgac acttggtgta actgatccga
     7321 ctatgatttt ttgtggtatc tataaagaac taatcacaca ccacgctatt tatgcaagat
     7381 tgattactat ttgtgaaaaa gctatggttc catttctcgg tgtgcatgta gcaagacaca
     7441 ctcatgcttc aatgctcttg gacgctggag ctactatggt agaagttcaa actagattac
     7501 ggcatacaaa aattagtcag acgatcgatt gttacggtca cttggcaaaa gaaacgaaag
     7561 aaaagactgt tgaaaaatta gtacaacact taaatattga ctagatggca tacaatatgg
     7621 catacagtaa aaaataaaaa aaggagaaac cctatcatat caaggtttct cctagcttta
     7681 tagtctattc ttcttcttcc gccatgaatg tattgaatac ttcttcaatc atgtcccatt
     7741 ctgcgtctgt ttcgatttgt tctaactcgc cttctgttcc atcttcgttt tcgatgtatg
     7801 cataagcttg taattctaca tcttcatctt ctgaaacacc agcaggatat aaaagaacat
     7861 agttacgtcc aaattcttct tgtccgtcaa ctgttagtag gatttcatat aatgtttcat
     7921 ttccttggtc atccaccaat gtgatgtgtt cgtgtccttc atggtcgtgg gaatggttat
     7981 gttctgtcat aagattacct cttttctttt attattaaaa taattgctta cctgagccgt
     8041 ctaaataatt ttgtaagatc atcacagctg ctaatttatc gatgactttt tttcgtttgg
     8101 ctcttgaagt atttgcctgc tctactagca tacgttctgc ctgaacagtg gttaatcgtt
     8161 catcttgata atcaactggc aaggagaata gttctttgat cttttctccg tatgacatgg
     8221 aagcttctgc ccttggtccg atggaattgt tcatattttt aggtaatcca actacaaacc
     8281 ggtctacttc atattgtgct actaattcct tcaaccgatc aaagccaaac tcttcttctg
     8341 cttcattgat ccgaatgatc tctactcctt gagctgtcca gccaaagggg tcactgatag
     8401 caacacctac tgtcttagaa ccgacatcca agcccattac tctcataaat tcactccatg
     8461 atttgagagg tagtccttga caattacttc catgatctca tcgcgttcgt gacggcgaat
     8521 caaatttcga gcatcacgat aacgaggaat gtaggacggg tctccagaaa gcaagtagcc
     8581 gacaatctga ttgattggat tgtagccttt ttcttccaaa gcccgataaa caatcgctaa
     8641 tgtttcgctc acttcttttt tgcgactatc gtcaaaacca aaacgtacgg tttcatctgt
     8701 aaaacccatg attctacacc tctttcccgc aaggtaattc cagcttacct tctacaacct
     8761 tattttactc gaagaaaggg aaaactacaa acaaatattc caaacttccg aataaattaa
     8821 gaaacactat ttgtatgttt ttttcctttt ttctgtagct ttatcaaaag tactcttttc
     8881 ataaagtata cgctatattt ctttgaatgt atgtttttac acaatttttt cataatattc
     8941 ataaaaaatt cgaatagctg ctactaattt tttgtttttg ttgcttgtcc tgtctcataa
     9001 ttgatcgtgt agccatcttg aacattgtag ataaagacat tgaattcaat ttttttgtct
     9061 tcaatgcttt ctgcttccaa ttgcactccc ctggctacca gttcattccc ctcaaaatga
     9121 ggagtgacac ggtagcgtac atgatgattt gtttctttga tatatgccgc aatatcattt
     9181 tcgtgagcaa gcatgtatgg agcattcaac gaacgtgtcc ctgtcatcaa gtttttaatg
     9241 ttgttatttt gaccagtcag ctggaaacca attaaatggc tgcgattata taaccattgc
     9301 ccgtcactta atttcttttg tttccaacct gtcgggtcaa tatacaaagg ctctctcttt
     9361 tcagtaggga acaaatcttt tccaagcata gcattggctt gtcctactct gttcaattta
     9421 tcaatatttg aatagctttc ccatgttcct ttggaaaggc taagatcctc ttttgtaaat
     9481 tccggctgat tcccattgat ttctatttct tgatgttttc catcatattc tggcacatcc
     9541 gctacttgag aagcttgtgg tgtggaatca aaaatagttg taatctgctg aaagatatct
     9601 gaatcttttt gtgtggtgga aacaccgaat gcccctgcaa tcacagcagc gacgatcccc
     9661 acgatcgcct tggttgtttt tttgctcatt tctttactcc tttactaaca gctccctaaa
     9721 tcttaacata tgttccccta taaataaata ctagaaagaa atagaaacag caaaaaataa
     9781 aacctgtttt aagatggctt aaaaatacaa aaaagagacg gattcctcgt ctctaatcag
     9841 tcaccactct atctgtaagg tatttattat tattcaaaaa ttttcttcat actcaagaca
     9901 atacactgat ttcacaaccg cttggtaaac ggtgcgcaaa agcttgcatc tgcggtaata
     9961 agtccatcca agttaaaaac ataagaagtt gtttttgctt ggctgttctt attacttgtt
    10021 gcagagcagc tttttcacaa cctattttaa gcgggtgacg ggaatcgaac ccgcgacatc
    10081 agcttgggaa gctgggattt taccactaaa ctacacccgc aatacaaaaa cagtatacgc
    10141 ctcttttatt ccttcctcaa gtttttttat tctttacgct tctggtatgt tttgtagtaa
    10201 aataaaacta atcaatcaat tattggagaa gatgctatga cgggaaaaga attagatctg
    10261 ttgctggaca cttgtttact cgctgggaaa atcatgatgg aaagcaatgc ggagatgtat
    10321 cgggtagaag atacgatgag tcgaattgct ttagcttctg gaaatttccg tttggtcagc
    10381 tatgtcactc aaaccggtct ctttattggt cttgatcgta cctcgaccat ccgaatggaa
    10441 caaattacca accgttcgat taatttagaa aaagtagtaa aagtaaatga tctttcacgt
    10501 aaatatgttg cttcagagct aacattagaa gaactttact gcgaactgca agcaatcgac
    10561 cgagaccgtt ctttctttcc tgtctggttg caaatcgtta gcgcggcagt gatcagtgga
    10621 acaattatgg tgttatttgg cggaaagatg accgatttac ctgtgacttt agtcattgga
    10681 ggattgggat acgcagctta tctatatagt ttgaaatttt ttagaatcaa atttttatcg
    10741 gaatttttat cttctttatt gattggcata gccgctatct acagcgtacg ttttggctta
    10801 ggaagcaatc aggatctaat cattatcgga tgtgtgatgc ctttagttcc tggagttcaa
    10861 attacgaacg ctatccgtga tttgctagct ggacattatg tctcaggagt ttctcgcgga
    10921 acagaagcga tgatgactgc tacgatgatc ggttttgcga ttgcttttat tttccagctt
    10981 ttttattagg aaaggaacac aagtatgggg acgatattta ttcagttttc ttttagtttt
    11041 ttagcgactg cggcatttgc cgttattaca aatgtaccta ggcgttcatt gatttgttgt
    11101 ggtctttctg gtgcttttgg ctggatgatc tactggatct gtgttcaaat aggcggatct
    11161 gctgcttttg gttcattgct tggttcttta ggagtagcat tcatcagcga tcttttctct
    11221 aaacgtttga aaatgcccgt aacgattttc aatattcccg ggatggttcc tctagtccct
    11281 ggtggtttag cttatcaagc ggttcgaaat ctcgttactg aatcctatcg agaagcggct
    11341 cattatgcgg tccaagcaat tatgattgct ggagcaatcg ctttaggtct tgtattatca
    11401 gaagtcttta accataacat ccgtaatttc aaagtaaagc gtgacgcaat catgatgaaa
    11461 cgaaaaaaac ggctttttaa ataaacgaag tgtaacaaag aaaaggttgt gaaagagacg
    11521 ttcagccttg agcgatgaca aaatatctca caaacattgc gacaagtaac cgcaggagca
    11581 ataagaagta attatgagta ttaaaaaaag ttttgtaaaa atagcttctc acatttttac
    11641 ataaaattga cttaatactg agaaactgac ttttgaacac cctctatctg taaaaaaggg
    11701 gctgcgacat gatttttgtc acggcccctc ttctttattc aaattttttc caaaacgttc
    11761 gttgataata aacgatccat agagcggaaa gtattagaac taaaccgatc acaggaatat
    11821 tcactaacca aaatggataa aacaaagcca acattccgta taagacgata agaataatac
    11881 tgatgatcaa tgaacccatc atagttgcga ctaaacccaa acttcctgaa cctctgttaa
    11941 ataattggtt aatattggtc cagttcagca gcagcaaccg ataatctcta gcgaaataac
    12001 gtagtgacaa taagtagcag ccgaataaag aaccaaatag caagctaggg ataaaaaaca
    12061 aaggcagctg aaaagacagt ccgcttaata atgcgatccc accagttaaa aaactctgca
    12121 atatccatcc gaatctgaac ttttctttta aatattggtt catagagatt ggcaaagaac
    12181 ggataaacag aaaattttct tgatccaaag aaataagatt gctgataaaa gaagtctgat
    12241 taactgttaa gaaagccaat gcgatcccta ccaggaaaac aacaccgatt aacttattat
    12301 ctaaatcagt taattttatt tcgcctccta gggcaaaagc aagaataaaa atgattggag
    12361 ttaacaagga agaagaaaga acttgcataa tcaaattagg ttcttttact aattgagcat
    12421 tgtaactaaa taaaagctga tgcacatttt ggttcttttt atgggttctt tttattttga
    12481 actcactgtt tgaatcagtc agttgctctg taagctttgg tactatcagc tgttttacag
    12541 caaggaaaaa tcccagagcc gtgatagcta gtattcccca acccaataaa ccttgttgag
    12601 aaagtggctg actggcagca tcatagaatg gcaataatat cgaaatcgga tgccgatctg
    12661 ttaactcatt ttcaatagtc cccgtttgat gattcatcca catgattcca gcaaatgcga
    12721 tcagcatcga gctgccaagc aagatactag aaactgtttt tctatgtttt ttaaacactg
    12781 ctgttcgagc caaaccaaaa acaatcaaac tagccagaca aaaaagaata atcaaaaata
    12841 gagaaaacaa aaggattgag ataatgatag taagcaaaat ccctagatca gctcgccatc
    12901 cggttaaaat aaacatgact agaagcggaa aaacaaaagg aatgatggtc aaagcaacta
    12961 ccaaaatctt tgctgaaaaa acctgttctt gtccaaaagg cagaggcaaa aatacttgca
    13021 ggtcatttcc ttcaaaaaag atattataaa tgactgatat actttgagtt aaacctaaca
    13081 taccaaaaag tgccacgtaa taagtaaaga aacctggcaa tttaacaaag ttcatagcaa
    13141 acatagcaaa tccgtaaatc agtaaaaaaa tcagccctga aaaaagattt tgagacaaaa
    13201 gatagatagt taatcgcttt cccttttttc ctttctctct tgctttattc gtgagctgtg
    13261 gattaacata taaaagatta actcgaatta attctaataa ttgtcgctta tacatacggt
    13321 ccatctcctg tcgcttgcct tccagccatt ttcaaataaa tcttttctag cgtttcatca
    13381 ggtgagccat tcaataattc actaactgcc ccctgataaa tcaattcacc tttcttcaaa
    13441 atagccagtt tatcgcataa ctgttgtgcg gtatccaata catgtgtaga aaaaatgact
    13501 gtttttcctt ttgcggcatg agccttcatc atttctttca aatcaaatgc tgcttgagga
    13561 tcaagtcctt gcaaaggttc atccaatacc caaatatctg gatctggcag caacgtgccg
    13621 atcaaaatcg ttttttgacg cattccatgt gaaaaacttg cgattgtttc attttgatga
    13681 ctatacatat caaaaagcgc tgtcaattct gctaaacgct tttctttttt ttgtgtgtct
    13741 aattcatagg cagctgaaat caagtcccaa tattctccag ccgtcaattg taaaaaaata
    13801 tctggggaat caggcacata accgattttt tgtttgatac tcaatcgatt ttccgtcaat
    13861 ttcattccat ctactaaaat cgttcccgat gatggttcaa taatactaac taaactttta
    13921 atcgtagttg attttccggc accattatgt cctaaaaatc caaaaatttc cccttgtctt
    13981 atcgagagag acaagtcttt taatgcttgt tttttcccgt aacttttact tacattgatg
    14041 aattcaatca tttctgtact ccttttgttt gttattactt tttattgtac ccttcgttat
    14101 tggtggagta aatgtcaaaa agagtgcata acaaaaaagg atagaaacga ctaggctgct
    14161 acttgggttg ttctcttcta caggaaaaca ctcttctaac aggtaagata tgagtctttg
    14221 ttttctttaa aatgattcat tttctatctt ttcttgcata aaattcttta gtttatcaat
    14281 acttctcttt cccatctcta gttgttctcc atttgcaaat gttactattt cgtttactct
    14341 gctaatagat gtaatgtttt cagtattaat gatataagct tttaaatctt tacataaata
    14401 ctcatattcg agtgattttt tatatttttt aattgtgccg tttacgagaa tctcttcatc
    14461 tttcaatact aggcctattt tatttttata acctggcatg ctcattagat aaaggatttc
    14521 atcgtaatgg atatagtgat cgctattacc ataacggaca gttgtccacc tttttttcgt
    14581 agcatgttga acaggatagt tttctttttc tttcaataag taactttgga tgcttttttt
    14641 atttttttca taagtgaatt cttttatcaa ataaccacta ggcgtaatct ttcgattaat
    14701 aacagttatt gctttattcg gatgagacgt tagataaaca attttacact tttcattctt
    14761 ttctctaagc atttcgccta gttcgatacc gctataatag gcgttcaaat cgatgtctag
    14821 gaaaaaaata tctgaggaat agatttcatt atttttaatg aattcaacaa attgtataac
    14881 gttcaatccc tgaacgatct caaatttcca aggacttaat aaaattctgg attcttccaa
    14941 aatttctact agcatttttt caaaaaccaa actatcatcc aaaataaata tacgcgttac
    15001 cataaaaagt acctccactc gatattttac tatcaaaatc atttcataca acttttcaac
    15061 atacatgtta ggaataaatt gtaattctct tcacaatctt ttccaacacc tttgaaaccg
    15121 atatcaaata ctttcaggat gctgcttcta aaataaatat caaacaaatg aatacatcat
    15181 gcaaaaaaag ccagacaacc gacgtccttg cgtgtcagct gtctgagcta tgtttattta
    15241 ttttgttctt ttaaaaagaa cgatacacat actgattttt cggagcagag actttctcag
    15301 cgtttgtaac aactacagat gggatttcac gcttgaatgg ttgataatag tctgattgga
    15361 tggttccttc tattttatac cattcatcat ttttaaccgt tactccttcc ggcatatgcg
    15421 tcaacaaacc aaagactcct gaatctgcca cacaatggat aatgccgaat cggaacaaga
    15481 agatatctgt attgctatcg ttcggtgttt ggtaaacaaa tccttcatag ctgatttttt
    15541 tgccaatgaa ttcgctaggg taattataaa ttagctccat aacttctaaa tagttttcat
    15601 ctgtgatctt gatagtttgc ttatccccat acttttcttt caactcattc atttggtcta
    15661 agtagtctga tttgttgaaa taaatactgg tatccggctt taagtattgt gtctgcatct
    15721 ccggatcccc tactgattct ttacttactg ggaaattaaa tcctttggct tctacgatcg
    15781 tagtgtcgag actaactgtt ggaaacaacg tccccacgat tactggcaaa gctagcagta
    15841 cataagcgat tccacgttga taaggttttg acaacccatg gtcatgatcg tgctcgtgtg
    15901 ccttttcttc tgcttttccg tttttgaccc acaaatacag ctgaactaaa gccaaaagag
    15961 cagataaaat cattgaaaga atagctaagt agcgataatg gacattgata tattgatcga
    16021 gtttgccaga aacttgcaag tacatcatca attcgaaata cccagataaa atcaaaaacc
    16081 gcagcatatt ttccctccta aataaataat gtgaatccaa taacgctaag ggcaatcagt
    16141 ccgatcagcg ataaaataaa gcgtcctgta aaatatcgtt tcatcatcag tagatttttg
    16201 atatcgacca ttgggccaaa gaccaaaaag gcagctacag gtgctgtgcc gaacagactt
    16261 aacaaagaag atcctataaa cgcatctgct tctgagcaaa gagacatcgt aaaggccaat
    16321 aacagcatga tgataatggc taaaatcttt gttgagccga gcgttagcat aattctagtt
    16381 ggtaaataag tctgcatcgc agctgcgatt aatccgccaa tgatcaaata acgacctgta
    16441 tcaaaaaatt cgtcgattga atgtgtcaac acatgcccag tttgatggat cagctgattt
    16501 tttggttcat tcttctcact ttgttcttct tcatggacat gatgatggtg attttctgct
    16561 actttagacg tgattttttc tttcaataca gcgtcttttt gaaaataggc aagccagaca
    16621 ccaatcacaa gggcaacaaa aaagctgcct atcacccgcc agcttgccat ctgccaagaa
    16681 ttgccaaatg cgataaaagt ggaaaaaatc acgattggat tgatgatcgg agcagtcagc
    16741 ataaaagcaa acgctgtgtg aactggtacg ccttttttaa caaattgatg aacgatcggt
    16801 acgatgccgc attcacatga aggaaagaaa aatcctaaga tcgaaccagt aaaaatagag
    16861 aagatacgat tttcaggaag ccatctcttc acacgttctg gggtcaaaaa tacttgtaag
    16921 gcgcctgaga taagacagcc taataatacg aaaggtaatg cttcaataac gatcgataag
    16981 aaaatcgtac tcatctgcaa aaccgaattt ggaataaaag aaaacatgag tttcctcctt
    17041 tttatttcta gttcattcgc tttgcaaata tacgctttta ttcaaaaaaa acaagttgct
    17101 ctgtaaattt ttacacaact cttatttttt accaaagcac ttcaattgac tttttctgtt
    17161 attcccatta aattaaggtc tcatacatat cacttctatc ataaaaggga gaataaaaat
    17221 gaaacaaacc actaacttga ctgaagttca agacatactg caacagtcat ccgttgccgt
    17281 catttatctt tcgatgccta attgcagtgt ttgtcacgct gttcgtccac gactagagga
    17341 acttctcaca cattatgata ttccggcact tcatttggat gcatttgaaa caccagaagt
    17401 agctagtaaa tttgaagtgc tgactgcgcc agttgtcctg atttttcatc aaggaaaaga
    17461 agtctttcgg caagcacggt tcatcgactt taaaaaaatc cgttatctac tagatgaact
    17521 gacagcagaa gatgattccc tttcttatga agaaatcttc cgaacaaaat aatcgttgtc
    17581 caaacagaaa aaagcgattg aacaagtgaa agttttgcct tcatttgttc aatcgctttt
    17641 tatttttatt ctgctgtatt ttcggaatgc gcatttgcgt cagaatgcaa gaaatagatc
    17701 aaggtttgca attcattcgt caaatcaaca ttttggatca atacatctga cggagcattc
    17761 aatcgagcag cggtaaagtt caagattcct ttgattcctg cttccgttaa ctgattgact
    17821 acttcttgtg ctctttcagc gggtatcgtt aaaattgcta cttcgatttg ttggatcttg
    17881 atttgttctg acatatcttc cattggataa acggggatac cgtctacgat gcgcccaacg
    17941 atttcctcat tcacatcaaa agcacaactg atacgtatgc tattactttg atggaatttg
    18001 tattttagta aagcacttcc caagttccct acaccgatca gcgcaacatt tgtcaattga
    18061 tcgtcgttta atgtctttgc aaaaaagtgc ataagatctt ctacatcata accataccca
    18121 cgttttccta attcgccaaa ataagaaaaa tctcgacgga tcgttgcact atctacttga
    18181 acggcttcac ttaattcagt tgaagacact tttttctttc cagcattatt taaaatcctt
    18241 aaatagcgat aatacaaagg cagtctttta gctgtcgcct ttggaataat atgatctttc
    18301 acgaaatgac ctccacgtat tgtctaatta catctttgat ttctccatca tagcagtatt
    18361 tataggaaaa aatcaattcc attgctcaga tattgtgaaa ttttattctt tattcattta
    18421 tttatcattt ctgcaaatct cgcagtataa tggaatttat ggtagactac taattgaaaa
    18481 atagtttttt atttgaggag aattcacaaa gtagaaaaga ggattccatg atattattac
    18541 aagccaatca gattgctcgc cattttggtg cagaagtctt atttgaaaac atacatttag
    18601 aaatcagtac aggcgctcgt gtcgctttag ttggcagaaa tggcgctgga aaatcgactt
    18661 tattaaagat cattgctgga attgaagcac ctgatgaagg aaagatcgct aaaaataaaa
    18721 cagcgactct cggatacctc gctcaggaca caggacttga ttccaatgaa acagtttgga
    18781 acgagatgct gaaagctttt gaacaagtta gacaaatgga agagcggatg cgcgagctag
    18841 agattttcat tagcgaaggt acgccagaca cacctgctta tagttcttat ttaaaagaat
    18901 acgaccggct gcaacacgat ttttcagatc gaaacggcta tggttatgaa aatgaaattc
    18961 gttccgtatt gcatgggttt aaattcgatt cttcatttta tgatcagaaa atcgatactt
    19021 tatcaggcgg acagcgcaca cgtttagctt tagctcgcat gcttttgcaa caccctgaca
    19081 ttttgattct agatgaacca acgaaccatt tagatatcga gacactttcc tggcttgaga
    19141 attatctgca aagctatact ggtgcattat tgattgtttc ccatgaccgt tattttttag
    19201 ataaagtagt caatgaagtc tatgaattaa gcagaagaaa aatgcgccat tacaaaggta
    19261 actattcgaa atatctagat ttgaaagcag aacagttagc aagtgaatgg aaggcttatg
    19321 aaaagcagca aacagaaatc cataaattag aagacttcgt tgctcggaac cttgttcgcg
    19381 cctctaccac aaaacgagcg caaagccgca gaaagacatt agaaaaaatg gaccggctgg
    19441 atcgtcctca aggggatgaa aaacaagcaa actttctatt cagtatagaa aagccttctg
    19501 gaaatgtagt cttgcaaatc gaagatgccg ctatcggata tgataatgtc accttatctg
    19561 aaccaatcaa tctagatatc cgtcgtcaag aagcgattgc tctagtaggt ccgaatggta
    19621 tcgggaaatc gacgttgctg aaatcaatca ttcaccagat cccttttatc cgtggaaaag
    19681 aaacgctagg gacaaatgtc accatcggct attacgatca aggtcaagct gatctgcata
    19741 caaacaagac gatcctagca gaattgtggg atgagcatcc taccactcca gaaaaagaga
    19801 tccgaagtgc tttaggtgct ttcttatttt ctggcgaaga tgtagaaaaa ccaatccctc
    19861 tgctaagtgg cggtgaaaaa gcacgggttg ctttagccaa gttagcgatg aacaaagaaa
    19921 attttttgat tttggatgaa ccaacaaacc atttagatat tgacaacaaa gaagtattag
    19981 aaaatgcatt gatcgattat gacggcacac tgctttttgt ttcccatgac cgatatttca
    20041 tcaatcggat cgcgacaaaa gtcgtcgaac tctctgaaaa tggcagcaaa gtctatctag
    20101 gagactatga ttattattta gagaaaaagc aggaagaaga agaaatcgcc gaattgttgg
    20161 cacaagatga gccagaatct gctcctgctc ccacgaacaa atctgattat taccaaagca
    20221 aagaacagca aaagcttatc cgtagccttc aacgaaaaat tactcaggtt gaagaagaaa
    20281 tggcgcggat cgatgaatgg atcgatcagt tggaacaaga aatggtcgcg ccagaaaacc
    20341 tggaagatca cgtaaaactc aatgagctga accaagattt agaagctgct agacaagatc
    20401 aagaaacaaa attgacggaa tgggaagaac taagcttgga attagaagaa tatgaaaatt
    20461 aacgaaaaaa ccaaaacaga aaccattcat gctgttttgg tttttctttt tttattttat
    20521 caaacaaaaa ttccatattt acctttttca ccaataagaa gaccaattac tagtcattct
    20581 cactaaagct tctaaataat agtaatcacc ccaaatacaa ggtgtattta ccccattatt
    20641 tttgggctta ttataaacag actgtgttaa aaagccatct tcttcttccg ttgtagcata
    20701 tctttctttc aattgtcgca taattttcca aacagcagac tggtataagt tcttttctgt
    20761 tttgtctaat agacctgatt ctattaattc taataatcca caaaccatga tcaccatact
    20821 agatgtatct ttttcttctc tgctagaatc atcaaagatc aaatcccaat aacaaatggt
    20881 atcttctggc aaccgattca taaaataatt ggctaatatt ttgcttaaat caaaatattt
    20941 ttgttctttc aaataacgat aacttaatgc aaaaccgtaa atcccccatg cttggcctct
    21001 agcccaacag gaattatcac tataaccttg atgcgtactt ccatatcttg gttttccatc
    21061 tttgacatcc atataaaatg tatgataagt tgaaccatct tctcttacta aataatctgc
    21121 tgcattttga atatgagcct gagcagcttt tttatatttt tgatttccag tttcttcact
    21181 cgcccaatac aataatggaa gattcatgca acaatccatg atcattctac cttgttgtga
    21241 aggatcacta ggatctcccc aagcttgtat aactcctgcc ttctcccaaa aacgctgaag
    21301 taatgtttct gcagcatcaa ttgaagcttc cttcattttt cgatttcccg ttattttata
    21361 atctgctacg gttgataaag aatacaaaaa accaagatcg tgatgattag tgataatttg
    21421 acagtcaatc ctgtggataa aatctatatc tgctttttca gctgtttgtt gaaataaagg
    21481 atcacccgtc ttctcaaata acaaccaatt aattcctgtc caaaatcctt ctgtccaacc
    21541 aatattgtct cttaatggat aacgtccttt tataggacac tcgcttggga attgatactg
    21601 actgttactg atacgtttga ttaacctctc cgtgtgtctg cgacaacgct cgatctcatt
    21661 attccattct ttttccatta attctttata acattcattt atccattttt ctggatgtat
    21721 tatctcttca aacatcactt tatcaagcat ttccccacca gcctttagca taattttagt
    21781 ctttttttat tgtttttatt ttggatagtt agcccggttg tcccatcaaa atcaattttg
    21841 ggacgattgt tccatacttc taaactataa tcccgatctt gatgagcaac cactcctgtt
    21901 ccgagccaat gggttccttt tccaaatgta ccctctaatc caggaataaa agtgttttcc
    21961 catgtcatca agtttgtatt gggcaaaccc ataatagctg tggattttcg tttaatagta
    22021 tcgtcactta aacagataat acctgaaaag ccagcttcac tcaccctata gttttccttg
    22081 tcttcttcta tgattattcc ttctttctca ggagaacatt caatagcaaa ccctgtctca
    22141 tatagaacat attctgtatc taattctact ttgtgtacgc gaatctgcca gccttcaaaa
    22201 ggaataagcc aagttctgat ttttgcctgt aaagtaggtt cccatgtaga ggcaagtacc
    22261 tctttcttac atacaatgtc tcgtacatta tttcgaacga tgaactgtcc ataggttttg
    22321 atgctctcat tcttaaaact ggtcgtgata tatgtgtccg ctcgctgaat ccctagcatt
    22381 gaatccattg ccatttctgc tttcaattga ttcgctcgcg gtatcgaaaa accaaattga
    22441 ctagaataag caaattttaa atatttttca ttggtcaatg tatggaaatt tggccctaat
    22501 tgtcccgcat tcaaaaaaaa tgtatgtcca ttatcatgtt gtatgagcaa attggcttct
    22561 gaaagaagtt tagttccttc acgaataggc ataggcattt ctttagccgt ccaatactca
    22621 tggtcttcag gtagcgccaa caataaaaaa atcttattca gccataatgg agataacgta
    22681 ctattatagg gttcagtcaa tgtcaattga gggtaggtat aaccaatatt caggatacct
    22741 ttttcatcaa atatttcttt ttgcatccac catcttatat tccgattgac taaccccttg
    22801 atttcaccta atttaaaagg caaaagatcg gcccacaaca tagctgacca aaagcttgaa
    22861 actgcaaaac gataaatcat gcttcgacca aaaggcacat ttgcaccatc ttccgcaaaa
    22921 aaatgaatat agtctctaga aaaatcaata gctcggttct tatatatctg gctaatgggc
    22981 ttttctggtt ctagtacgct ataaatcaaa ccataataat gaaatgcaaa aggattataa
    23041 taatcttggc gacctcttga actgtctcga taccagccat tttgaagata acaattttct
    23101 atattatcaa atgcttcttt cagtgctgat tctttaactg gataaccaaa tttttggata
    23161 attgttccga caattatctt aaaaaattgc caattaccat ctgcacattc atattcaaaa
    23221 atttgcgaga accaatgaat aatctggctt ttttctcctg tatctaattt tttccataat
    23281 aattgttcat gatgatataa cgctaataac attgcgggca tttctaccat acgctggtct
    23341 ctttcatgta tttctcccca ataatcggga tgggaaggat ctgttccagc ttttattcct
    23401 gatagaatta atttcaacca tcgttcatct aattggtcaa ttgcgggccc cgctccccat
    23461 aaaacccgag agaatccttc cattcctgca attttatttc catatcctac cccttgatgt
    23521 atataatcaa tttgtgcgcc acttgctcga taaaacggct ggagtggttg atttatcttt
    23581 ttaaataagt caaagtaatc ctgtctggtc cttaatagtg gtactggatg tttcattgta
    23641 ttttctcctc tttttactac caaatagcta attccgactg ttctaatcga agtaagcctt
    23701 caataaaaaa ataatcagaa tagatcagtg gcacattata agtcagttct ctatggtatg
    23761 cttctgctcc gcctccaatg atcccatctt catccatatt ccaatttgca tagtgctttt
    23821 ctgtcttttg gagtatattg atagcagctt catgatacat ttttgatcgt acagaggaaa
    23881 catatcctgc taattccaga agaccgcatg cagcgcatac tccagcactg gtatcaatat
    23941 tcgaatcttt tacagcaaaa tcaatgagag gaatataacc agttttttcg attttctgaa
    24001 taaaatttac tgctatcttt tctgctatag ctagatagta cggatttttt gtgtaacgat
    24061 aacttaacgc gaatccatat aaagcccatg catttcctct gctccaacaa gaattctcat
    24121 tgtatccttg cccgccaagt aaccgaatat atttccctga ttctgcatca aattctgcga
    24181 tatgcccggt tgatccatct ttcctcacta gatacttagc tgttgtatct gcatgctgcc
    24241 gagcaatttt agagaacctc ggatcaccag tttccctcga agcccaatac agtaatggta
    24301 aattcatcat actatcaata atcatccaac caggtttatg gtcattccat gctactaaat
    24361 agttccctga aatattatag cgtccagcaa gtaccgtagc tgcatgtaac cctagttgtc
    24421 gactatgttt gttttgagac tgttgataat gtgcaatagc cgatggtaag aataaaaaac
    24481 ctacatcatg atgaacgtct gaaaaatggt acagggcaga ttctaataat tgttcttgtt
    24541 gtattgctgc ctctttgaac ttttctcgtt ttgtcttgtg aaagagctgc cataaaatac
    24601 cactccaaaa accattggtc caccagtcga ttcctctgtc ctttattacg tctgtatatt
    24661 ttccgttgta agaaatatat ggaattttat tccccattct gtctaattcc gcatctatct
    24721 tttcagaagc tacattcaaa atttttcttg accattcctt cgtctgttca ttcatggata
    24781 tcccgccatt cttttaattt ttatgaatgt ggagttgctc ctagaacgaa ctagatggtt
    24841 aacattcgtt atttttttta cttatttgca gctccaatgt cattctcctt aaatttagac
    24901 tgcgcccaca cataaatcaa gaccattggg atcactgaag ttgctaaaat tagcataatt
    24961 gcgccataat taattggctc acctgtacta gaaaccgtca tatttttgat aattaaggga
    25021 accgtatatt tatctttatc tgaaagcatg actaatggaa atagatattg attccaactt
    25081 cccataaaga taagtaaacc actagtaata atcgtaggtg ataaaatcgg tacagcgatt
    25141 ttcgtaaaaa tcacccactc attggcacca tcgattctgg cagcctccat cagtgctgta
    25201 ggaaattgac tgctatattg tcgcatcata aacactgaag ttgtactggc aatcgaaggg
    25261 atgatcacac ctgcataagt attcgataat cctaaacgac tcataatgta aaataaagga
    25321 atcaatgtgg taaaaaaagg caccatccta gatagcataa ctgtattgaa caacagttta
    25381 ttccccataa aacgatactt tgctaatgca taacccgcca ttgtagaact ggctgtagct
    25441 aaaactgtac tgattacagc aataacaatc gaattccaaa taatcaaggg ataattatat
    25501 ctcgccatga tggcttgcca gttttttaat agcatatccc caaacttgaa attgattccg
    25561 ccacttaaaa tttcttgatt actttgcgtt gaagctacaa tcatatataa atatggcatc
    25621 aaaaatatta aggcaccaaa cacaataatg acgtacgtaa aaattctgct ttgtatcttt
    25681 tgtttagtca tttttatcac ctccgaattt aaattgaata gccgataata taacagatac
    25741 aaacaccatc gtccaggcaa tagcagaggc ttttccaaaa tcaaccattt caaaacttgt
    25801 tttatataaa ttgactccta cgaccaaagc tgaattttct ggtccattgg aagtcccaaa
    25861 gaatatattt gggatattga aattacccaa gccattgata gtggctaaaa ctgtggccat
    25921 taaaatgatt ggctttagca tggggatcgt taataaaaag aattgccgaa atttcgatgc
    25981 tccatctatt tcagcacttt cgtatatctc tttagaaatc ccttgaagac cagctaaaaa
    26041 taaaatagtg ttatatccta cactaagcca aatcatcgtg atgatcattg atattcgtat
    26101 ccaaaaagga tttgttaacc actgtacacc gttaattcct agcgcattca aaaatccatt
    26161 gaataaccca gtcggattga aaaaagtcat gaatacggaa gctacagcca ccgttgatgt
    26221 aatggttgga atataataga cagttctaaa aaatcctttt ccttttaact gtgctgaatt
    26281 caataaaaca gcaaagtaaa tagctaatag catcgttatt ggaattgatc ctgccatgat
    26341 aatcaaaaca ttcgtgtaag atttaataaa caatggatct cggaagatag ctagataatt
    26401 gtcaaatcca acaaattcaa atgagtagcc aattttcata aaactaaaag caaacgagat
    26461 aatgatggga atcaaaatcg tcacaataaa gaaaataaca aaaggtgtga ccaatccata
    26521 agcacttttt ttatgagacg tatctgttgc ttttttcttg ctgttcttta ttgtcttgct
    26581 tggtaacgaa gattgcatca tcgttaagtc ctcctaatat tttttaatca ccagttaatt
    26641 ttacgccgta cttatgagca aaattttctg cttcttttag atatgaattt tcaaaatcac
    26701 ctgtttgcca atagttatat gcagcggtag tcaaataaga cgtagcatct gaataagtgg
    26761 ctggtaaaac agtatttgat gtattttcat tgattttatt caatagttca tagtattttt
    26821 gtcctcctta gtagtcaaac tttttctcag ctgcttctgt ttgataggcc aatgagttag
    26881 atgtagccac gcccagctcc agtgcgttgg ctaagcattc ttcatctgtc agcataaatg
    26941 taagaaattg ttgtgccact tgtggatttt ttgcatcttt agggacataa aaacttgatc
    27001 ctcctgatac tgcacctttt cctggatttt cttttgaaaa aggaatcagt ggagccatgc
    27061 gccatttgtc agatgcatca ggaaaattca aagacatatt cgtagcatac cagccgccag
    27121 caacaaacat tgcagattct tgaaatgctt tctcagcatc ttgtgcaccg tagaaatgta
    27181 caatatctga gtcgatcatt tctttgatta actttgcagc atgtttcgct tctttagtat
    27241 tcagacggat atttccttct tcatcaagca aagattgatt ctgctgggct agcatgttga
    27301 taaacaattc ttggtcccca gattctggca aggcaattcc aaaactacca gttttttctt
    27361 ttaatgcttt tgccacctgg atatattctt cccaagaact gatttcttca aaatctacac
    27421 ctatttcagc aaattttttt ggttgataat aacaaagtgc tggggtaaaa tcactagccc
    27481 aaggaataat cgtttcatta ctcgtttgtt gacgcaaaat attcaatttt tgatcataaa
    27541 actgatcgcc atatttgtca taaaatccat attcatcagc actataaaaa gcatcttgaa
    27601 atttttccag cacacctgct gctgaagtgt ctgccatgga gataatatcc ggcatatctt
    27661 cgtgtgttac caattttggg gtgatcattt gtactgttgc tgttcccgaa gctacattca
    27721 caatttttaa gtcaatattt gctccagttt tgcggttata gatttttgca gcattttcaa
    27781 catagtttgt cagtttgccg tttgcgacat atacttctaa tgtagtggct ttttttatca
    27841 ttggatctgc gatgtttgct gttacttctt cgttagtttt tccacatgca cttaagctga
    27901 ataatagggt aatgtttagc aaagctatca ccaatttgta tctttttttc atgtctatcc
    27961 cttctttctt ttcaagttct tatataaaac gctttcactt a
//
LOCUS       DACGEU010000032        27837 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.032, whole genome shotgun sequence.
ACCESSION   DACGEU010000032 DACGEU010000000
VERSION     DACGEU010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27837)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27837)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27837
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.032"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(547..909)
                     /locus_tag="IXR40_001281"
     CDS             complement(547..909)
                     /locus_tag="IXR40_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361140.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
     gene            complement(983..1363)
                     /locus_tag="IXR40_001282"
     CDS             complement(983..1363)
                     /locus_tag="IXR40_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HAQ4361141.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            1445..2620
                     /locus_tag="IXR40_001283"
     CDS             1445..2620
                     /locus_tag="IXR40_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAQ4361142.1"
                     /translation="MIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADMDFLSPG
                     GVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVLTSLAAA
                     VQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDMEKKIEEN
                     NVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHTFTSMLT
                     IDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEINTFGLI
                     GTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLDFTAYIS
                     DDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYALETID"
     gene            complement(2697..3281)
                     /locus_tag="IXR40_001284"
     CDS             complement(2697..3281)
                     /locus_tag="IXR40_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAQ4361143.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
     gene            3482..4480
                     /locus_tag="IXR40_001285"
     CDS             3482..4480
                     /locus_tag="IXR40_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAQ4361144.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            4592..5101
                     /locus_tag="IXR40_001286"
     CDS             4592..5101
                     /locus_tag="IXR40_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HAQ4361145.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(5131..5790)
                     /locus_tag="IXR40_001287"
     CDS             complement(5131..5790)
                     /locus_tag="IXR40_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HAQ4361146.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTKKKEL
                     V"
     gene            complement(5792..6556)
                     /locus_tag="IXR40_001288"
     CDS             complement(5792..6556)
                     /locus_tag="IXR40_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HAQ4361147.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(6564..7241)
                     /locus_tag="IXR40_001289"
     CDS             complement(6564..7241)
                     /locus_tag="IXR40_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HAQ4361148.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(7278..8663)
                     /locus_tag="IXR40_001290"
     CDS             complement(7278..8663)
                     /locus_tag="IXR40_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HAQ4361149.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(8873..8957)
                     /gene="ffs"
                     /locus_tag="IXR40_001291"
     ncRNA           complement(8873..8957)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="IXR40_001291"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(8980..9495)
                     /gene="tadA"
                     /locus_tag="IXR40_001292"
     CDS             complement(8980..9495)
                     /gene="tadA"
                     /locus_tag="IXR40_001292"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HAQ4361150.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            9602..10459
                     /locus_tag="IXR40_001293"
     CDS             9602..10459
                     /locus_tag="IXR40_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fis family transcriptional regulator"
                     /protein_id="HAQ4361151.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYHYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            complement(10540..10875)
                     /locus_tag="IXR40_001294"
     CDS             complement(10540..10875)
                     /locus_tag="IXR40_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361152.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(10942..12312)
                     /locus_tag="IXR40_001295"
     CDS             complement(10942..12312)
                     /locus_tag="IXR40_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NOL1/NOP2/sun family putative RNA methylase"
                     /protein_id="HAQ4361153.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            complement(12390..12926)
                     /locus_tag="IXR40_001296"
     CDS             complement(12390..12926)
                     /locus_tag="IXR40_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAQ4361154.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            13235..14716
                     /locus_tag="IXR40_001297"
     CDS             13235..14716
                     /locus_tag="IXR40_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAQ4361155.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLIKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
     gene            complement(14819..15526)
                     /locus_tag="IXR40_001298"
     CDS             complement(14819..15526)
                     /locus_tag="IXR40_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HAQ4361156.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
     gene            complement(15605..15943)
                     /locus_tag="IXR40_001299"
     CDS             complement(15605..15943)
                     /locus_tag="IXR40_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HAQ4361157.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            complement(16054..17016)
                     /locus_tag="IXR40_001300"
     CDS             complement(16054..17016)
                     /locus_tag="IXR40_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HAQ4361158.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            complement(17031..18362)
                     /locus_tag="IXR40_001301"
     CDS             complement(17031..18362)
                     /locus_tag="IXR40_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAQ4361159.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            complement(18370..19050)
                     /locus_tag="IXR40_001302"
     CDS             complement(18370..19050)
                     /locus_tag="IXR40_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HAQ4361160.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            complement(19269..19748)
                     /locus_tag="IXR40_001303"
     CDS             complement(19269..19748)
                     /locus_tag="IXR40_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HAQ4361161.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            complement(19875..21554)
                     /locus_tag="IXR40_001304"
     CDS             complement(19875..21554)
                     /locus_tag="IXR40_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HAQ4361162.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            22102..23604
                     /locus_tag="IXR40_001305"
     CDS             22102..23604
                     /locus_tag="IXR40_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4361163.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            23617..24279
                     /locus_tag="IXR40_001306"
     CDS             23617..24279
                     /locus_tag="IXR40_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4361164.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(24380..24583)
                     /locus_tag="IXR40_001307"
     CDS             complement(24380..24583)
                     /locus_tag="IXR40_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HAQ4361165.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(24694..25878)
                     /gene="iadA"
                     /locus_tag="IXR40_001308"
     CDS             complement(24694..25878)
                     /gene="iadA"
                     /locus_tag="IXR40_001308"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HAQ4361166.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            complement(26035..27774)
                     /gene="yfcC"
                     /locus_tag="IXR40_001309"
     CDS             complement(26035..27774)
                     /gene="yfcC"
                     /locus_tag="IXR40_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HAQ4361167.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
BASE COUNT         8272 a         5803 c         4709 g         9053 t
ORIGIN      
        1 gagtgtttcc cgattcgttt ttggctgccg tagcaacttt tatatcatat cagagagaca
       61 agcgattgtc aactcttttt taaaagtttt tttcgatttc gtttttcgaa atctttcagc
      121 aactcattta tcataactta tcgtttgtta tttgtcaaga acttttttga agtttttttc
      181 gatagaatca agcttcgcaa gtggttcttt tttaacgact cagttatctt atcatgtcgt
      241 tagtaacatg tcaataacta ttttttaaat tttttagaaa tgtgatataa catccacttc
      301 agaatcaacg ctgttaaatt tatcatgtat ttcttccttg gtcaactata aattaagcat
      361 tactttgtga aatgattttt cgatcaatta ttattattcg ttatacaacc gttttcaaca
      421 tattttgaaa ataaaatgca ctaaaaaact atctttagca gaacatttca ttgtattttt
      481 tggaccaaac aataaaaaaa gaagtttgaa aaaaattcaa acttctttgt tcgcttaatc
      541 tgtattttag aagaaaggca ctccctctac ttcgtaagtt ccaagaacag agcgcatttg
      601 acctggttct tcccaaatat atccttcgcc taattcttct ctttgattct tttgttcagt
      661 ttcaaagaca aacaacggaa cattttcctc tttaatatgt gtatttgtca attccatcaa
      721 actaatcttg ctaacatcga tatgaactat ttcttttaag aaattaagta tattcgctaa
      781 accagtcttt ccttcagaaa gttccgctaa cgcaaattcc aacttgtcat caattgaatg
      841 gaccaaaaat tttttagtac catcctccaa atgcaacata attgtaccag caactctttt
      901 gcttgccaaa atttccacct cgatcaactt gttctatggc ttacataaaa attctagcac
      961 attttcagaa aaaatacact ttttatttct tattttcttt ccgttctagt tcagataatg
     1021 cttcttctat ccaaataggt aactgctccg caatagtggt aaatccgatc ttacgatttt
     1081 tattcgtgaa ataccttttt ctgcgatatg gaacagctgg atttgttttt tctaacgttc
     1141 ttaaagataa actgattttt ttggaatatt catcaatgtc gatgatctga actgttactg
     1201 gctgtccgac ttttaacaat gaatggatat ttttcgtata accggattgt acttctgaaa
     1261 catgaataag tccttgcgtc tcgttatcaa gagaaacgaa tgcgccataa ggctgtatcc
     1321 ctgtcacttt tccttcaatt atttgtccaa ttttataagt catctacttc cctctcttcg
     1381 catttatcat tatactgtaa atagctcaaa aaaagaagcg acgaaaatga ctggaggtct
     1441 taagatgatc gaatttgata aacagatttc aagaaaagat acagaaagtg taaaatggga
     1501 cgcaattgct gagacatatc aaatggatga cttacttcct ttgtgggtag cagatatgga
     1561 cttcttgtct cccggtgggg tagctaaagc gtttagtgaa tacatcaaac atggaatctt
     1621 tggttatgcc actctgtctg ataaactata tcaggctatc attcattggg aacgccaaca
     1681 ccatgctgtg gagttgacga aagaaaatat cgtttttaca agtggtgtgt taaccagttt
     1741 agctgcagca gtacaaactt ttacaaaacc aggcgattct attttgattc atgacccagt
     1801 ttatcctcca ttttcctcta ttatagaaac aaatcaacgt cacatcgttc gaagctcttt
     1861 gctagaaaaa aataatcatt tcatcatgga cttgtctgac atggagaaaa aaatcgaaga
     1921 aaacaatgta aaagcaatga ttttatgcaa tcctcacaat cctggagggc gtgtttggag
     1981 caaagaagaa ttgaaacagt taagcgaatt gtgtttaaaa catcaagtga ttctgtttag
     2041 tgacgagatc catcaagatt taactttatt cgatcataca tttacttcca tgctaacgat
     2101 tgatcctaat ttagatgatc tactagttgc ttttacttcc gcaaccaaga ctttcaatct
     2161 agctgcaatc aaaaattcaa tggtatttat caaaaatcca gagatgaaag ctgattttga
     2221 aaaacattta gtgatgaacc aacagcacga aatcaacact tttggactga ttggaaccca
     2281 agcggcttat gagacgggtg gagaatggtt aagccaactg attccttatc tagaaaaaaa
     2341 tgttcaaaca gttaatcagt tttttgaaca gtatcttccg aaagtgagaa taatgaaccc
     2401 tgaaggaact tacttaatgt ggttagattt taccgcctat atttcagacg accaagaatt
     2461 ggagaacact cttgttcgga aaggaaaagt cgtattaaat cctggcatca cgtttggtcc
     2521 ttccggtcat gggcatatgc gcttgaatat tgcttgtcca gaagaaactt tactggaagg
     2581 acttaatcga atcaagtatg ctttagagac aatcgattaa atcatttatt caaaataaaa
     2641 ggacgagacc ttactaggtt tcgtcctttt tcataattac tccgtaccat accaaactat
     2701 tctgaaattt caattgtttc aatcactaca tcatgtacag gtcggtcttg tggaccacgt
     2761 tgtacatttg cgatttcatc tactgtgtcc atcccttcta gtacatgtcc aaagactgta
     2821 tgtcggaaat ctagccaagg agttccgcca cctttatacg cttcaatgat ttctgatggg
     2881 aatccagcac cttctagttg tccaagcata ttagctggca catttgtgtt atttacaata
     2941 aagaattggc ttccgtttgt gtttggacct gaatttgcca tagataaagc tccgcgaagg
     3001 ttgaacagtt cacgactgaa ttcatcttca aaactttcgc cataaatact ttcgccaccc
     3061 attcctgttc cagttggatc gccgccttgg atcatgaaat caggaataac gcggtgaaaa
     3121 atcacgccat cataataacc ttttttggaa agttcaatga aattttgaac cgtcttcggt
     3181 gctagttcag ggaataattg aacagtaatg tcaccacggt ttgttttgat aacagctttt
     3241 ggtccttttt cactttttaa atctagttgt gggaatgcca tattgtttcc tcctaatatt
     3301 tgcatacttc ataataataa taacataata cctaacctct cgtaaaaata ctagatttgt
     3361 tttcttttat ttttcatcac tagatacatt ctataactta ccgtttcgat ttcgaattca
     3421 aacatttttg agaagcattc tcaattaaat tctgatatag tgtgaaaagg gaggaatttt
     3481 tatggaaatc tatgacatta caatcatcgg tgcaggtcct gtagggatgt ttgccgcttt
     3541 ttacgcagga atgcgccaag ctaaaacaaa aatcattgac agtctacctc aacttggtgg
     3601 tcaattagca actttgtatc ccgaaaaata tatttacgat attcctgggt atccagcaat
     3661 aaaagcaagt gaattaatcg atcaattaga aaaacaatta actactttta accatacatt
     3721 ccatttaaaa gaagaagttc tctcgcttac tcgtgaagac gaagttatcg agattactac
     3781 aaataaaggc atccattatt ccaaagcagt cattttagct ttaggaaatg gttcattcca
     3841 gccaagaaaa ttgaatttag ataatgctga atcatttgaa aaccacggat tggattattt
     3901 cgtgaatgat ttgatgaagt atgctggaaa aaaagtcgct attgctggag gtggtgattc
     3961 tgctatcgat tggacgttga tgttagagcc tattgcaagc gaagtttact tgattcatcg
     4021 tcgcccggaa tttcgtgcgc acgaacatag tgtatcacgc ttgaaatctt catctgtcaa
     4081 cttgcttact ccctatctca tcgatggatt atcaggcaat aatggggaac tgacagatat
     4141 ccggttaaaa aaagtgaaaa gtgacgagac gattgatttg atgattgatt ctctgatcgt
     4201 caattatgga ttctcttcta atttagaaca tctttcttct tggggacttg atagtaccag
     4261 aaatgccatt actgtaaaat cagatatgtc tacttctatt ccaggcgttt atgcagctgg
     4321 tgacatctgt acctatgaag gaaaagtgaa actgattgct actgggctcg gtgaagcacc
     4381 tactgcagtg aacaacgctt tacactatat taatccaaag gaacgaactc agcctggtca
     4441 cagcacaagc ttatacgata aaaatcttcg tcctagttga ttttttatat ctctttgcat
     4501 ttcaagttaa acccgaaagc agtttcttgc atttttttca tgttccgtta acatgaaata
     4561 gagaaagaaa aaataaaggg ggagcaataa tatggtcgtc aaaactgaga ctttagaaga
     4621 aaaggcaaga gaactattga aggaacgtgg cgtaactgta gaagatatcg cacaacttgt
     4681 catgttttta caaaaagact atatttctga tttgactttg gcggattgta ctgaaagtgt
     4741 caacagcgtg ctaacaaagc gtgaagtaca taacgccatt atcactggaa tccaattaga
     4801 tatattagca gaaaagaaaa aattgatgag tccgttgcaa catattatcg aagatgacga
     4861 aggcctttac ggtatcgatg agatcctagc cttgtcaatc gtgaatgttt acggtacgat
     4921 cggctttacg aattatggtt atatcgacaa ggtgaaacct ggtattttaa aagaactaaa
     4981 cagccacgat ggcgttcatg tccatacctt cttagatgat atcgtcggag cgatcgccgc
     5041 tgctgctgcc agtcgattag cacacaaaga accagaaaaa agaagtcgcc ttactcaata
     5101 attcaacaaa aaaagaaaga aaacgtctat ttagacgagt tctttctttt ttgtttgttt
     5161 caagctattt tttcctaaga aaagaaaaac agcaaaaaat aattctaata atacaaaaaa
     5221 taagataaag ctatgcatga aaaattcttc tggaagtaca ttgatgattg gatcagtaac
     5281 gggatcgaat aaccagtcat cgttgttgaa aaacgtttca tgaaaaagga taaaaaagcg
     5341 atcaaatcct atcatcatga aaaaaccgaa aacaactggc agtaacatgc cgatttgaaa
     5401 cggacgaatc aaccgccaaa gccgatcatt cttttgcaaa tatttgataa acaaaatact
     5461 cgggatcaaa gtgatgaaaa acacagcata atccactaaa aacaaaattt tcacttcata
     5521 aaagtgatgg gctccgctag cagaaactgg gaaatctggc aagctgagga tggttttgaa
     5581 gggattattg agataattca ttaggtgatc aaaatttttc agtaacgtct cttgatctaa
     5641 agaagtataa tccaaaattt gcaaatgtcc gatatcaaat acgtatagtg gtcgaaagtt
     5701 gatcgtcaca ccaactgcca gactgatcag tgtcagaaat aggctgaaca atccagcata
     5761 ttccatccac tgccatctcg aatttttcat attagaagct ccattcatcc agtgattgtt
     5821 tcacataggt agctgggata ggcaacccag gtacatcttc ttcttttgta aaacctgata
     5881 aaacgagcaa agtatctata ttattgcgta tcccagcttg gatatctgtt tcatagttat
     5941 ctccaaccat gattacttct tctttttgca gccctaatac ttcaacggct ttatccataa
     6001 tgatggcttc tggttttccg atgtagatcg gcggcgtttg ggttgctgtc tctacaaaag
     6061 agatgactga ccctgctcca ggaagaaggc cgcgttcagt aggtatattc ttatctgggt
     6121 tcgttccaat gaaagtagca cctttttgaa tagcaagtgt tgctttaact actttttcat
     6181 aggtcagata attatctaag cctaccacta catagtcagg agcctcttct tcccatgtaa
     6241 atccggcagc taaaatcaag tcaatcaatc ctgcttctcc gataacatag acttttttcc
     6301 cttttccatc tgctttcata aaatcgattg ttgccaaagt agctgtgtag actgtctctg
     6361 gagctacatg aatgtcaaac tcatctgcta gacgattagc tactgtttct ggtgacttag
     6421 tcgtgttatt ggtaacaaac aagaaaggta attttctttt ttgcaattct tccacaaatc
     6481 gtttaccggc cggtatgggt tgtgtcccac gataaatcgt tccgtctaaa tcaattaaat
     6541 atcctttata gtccattcat ccactactct tccctttttc tgatcgtaaa tgctgttttt
     6601 gttttttcta cttgtttagg ttgttcttgt ttttttactt tttcagaggt ttttgctgac
     6661 tctgtttttc gatttttaat aaccggtttt ttgcgattag atgcgactgg tccttttttc
     6721 tcatcgatat acgcacgatt atggtttttt ttcttttttc ggcgctgagt tgtcttttct
     6781 tttttaccgc cgattctctc gatgacaaaa tacgcacaac caaaattgca atattcgtaa
     6841 agatagtctt ccaaggaatc gattcgctga tctggatgcg cccgtcgatt atccgcttgg
     6901 aaaaatcctt ttaggcgtag ttgttcataa ccccaatctc ctacgatata atcatatcgg
     6961 gctagtacat cactgtaacg ttctccaagc ttttctgcat taaatccttc acgataatcg
     7021 gacacaagcc gataatgtct ttcacctatc aaaaaattac tgtcatctaa cagtgtcact
     7081 agctcgcctt tgactttttc tgctttaggc tcctcaacga tttcttccaa agcagctgtc
     7141 agttcttcgg tgactgttgt ttcctgttca gctgatgatt ttttcttagc aatttctgtt
     7201 ttatgctcaa cgttctgctg ttcattttgt tttgcagaca tgcgttcacc acctatcttt
     7261 tttattatac cttgttttta tttgattggg tagtgagctt tcaagtaatc tcctaccaca
     7321 cttcggataa attcagggaa caaaaattca ttttttccag caatctcaat cgttggaaaa
     7381 aatggaacaa acatcaaatg atctacggta gtaaaagtat aatttttatt cagatcgatt
     7441 ggcttgttct tccaaaagac ttgatggtta atagaatcat atgtgattcc attatagacc
     7501 atctgcccaa aaatcttacc gcgaaatccc attcccttca taggatagtt acgtaaaaag
     7561 ttacgatttt tttctatttc taaaactaag cggatcagat catttccacc caatgtgaca
     7621 tttaacaagt gcatcggatg cggcaacgca gtgtgaagct gatcctgatt gacccgccct
     7681 tttggaattt cagttaaaaa cagaccactg tttaatattg ctgcttccgt ctttcctcgt
     7741 tctttcaccg cctcaaaggc tacttggata aacgaatgct cattgaagat atctagactc
     7801 agagaaaatg gcaaatctgc tacttctttt tcttttaata attcatgccc acgttctaga
     7861 taactattta tttcttgttc atcttctgta aaagctgtca ttgtttcggt agggatggct
     7921 ttggctgaat gcttaaggat ttttttctct tcatcgatgg ttaaatggac ttcaccgaca
     7981 tactgcccgt actttccagc ggctgctatt tggacatcat tgattacgtg accttctctg
     8041 aataaatgat gggtgtgcga tcctaaaata acatcaattg ctggtatttc ttttgcaatt
     8101 tggaaatcat cctgaatccc gagatgactc atcaaaacta aaacatccac ttgtgaacgt
     8161 aaatcttcga ctaattctgg caaaatatca taaggattcc gtatgtccca gccattcgga
     8221 ttataagtaa gcggaaatgg agcagtaaat gcaattagtc cgattttcgt ctggtgtttc
     8281 gttgtaatga ttttatatgg tttcgtccat gccggtggct ggagcgtatt tttatcgaat
     8341 aagttatcca ggatgatatc aaactcagca tgatcgtata aatgattcaa ctcttctttg
     8401 gaatttccta cgccttcatt gtttcctatc gtcgctgcat cataaccaac ttcattcatc
     8461 agcaagatat tttcctgtcc attcgttgct tctgacaatg gatgccaacg atccacaaaa
     8521 tcacctagat ctactgcaat cgttgtcgtt ttttctttct tttcgttttc tcgtttacgt
     8581 tgatccaaaa accttctgat ccttggccaa ttttctaaat gagaatgcag atcattcgta
     8641 tgtaaaatca ctattttttc catgtaccct ctcgcctctc tttatcttta tcataccata
     8701 ggcagctttt tcttccattg aaacaagctc tatttcagag tttttcctgc cttgaagcaa
     8761 attgtataag tacaatattc gataaatcag tctggctaaa aaatcaggaa cattcatttt
     8821 tacagtacta taaaaataaa aaaaacagac ccgaaagtct gttgtcgttt cattataatc
     8881 agacacatgg cggaacctgc ttagtgctgc ttccttccag acctgacacg cttcacaagc
     8941 ccaccattgt cctagccttt cggcaaagaa tagtatacct tatttttcat tcgttgacca
     9001 gtcttttttt aatttctttt ttcgctggcg gagctttcgg aaaaagtcag tcaaaatcat
     9061 cccacattcg tcttctaaaa tgccaccttc tacatatgct tggtggttaa accgctcgtc
     9121 ctccaaaaga ttcatcaagg taccggctgt tccgcctttt ggatcatacg cgccgaaata
     9181 aacttctgct acacgagaca aaatcatcgc gccgctgcac ataggacaag gctctaaggt
     9241 aacaaaaagt gcagcatctt ccaagcgcca gcttcccact ttttcacagg cttccttgat
     9301 tgcaagcatt tctgcatgtg tagtagcatc ttgcgtggtt tctctaaggt tatatcctct
     9361 tccaatcact tttccatcca atacaaccac tgctccaatc ggaacttcat gaagcatttc
     9421 tgctttcttt gcttctgcca atgcaaggcg catccatttt tctttttcta ctgcatcaag
     9481 atttgtattt accaattacc cttccctgcc tttgtttttt cttgttttac tttagcatat
     9541 gataaaaagg ctgtaactaa cttttttttc tatggtaaaa taaatacaag aggtgaacaa
     9601 gatgaaaatg gataaattac ttgctcttta cccacaagca cagaaaaaaa actctccagc
     9661 atcagaagcg gatatccttt cttttgcaat tgatgatgct tttatctgga tcaaacaaga
     9721 ttcattatct caacaagaaa ccagcctttt gaaagcgtta ttccctgtaa tcaacgatca
     9781 aaaaaaacac ccatggtatc actatctttt taaagatgct tcttgtgttc aagaaaaaag
     9841 ctttcgtttg atccagcttc acgtcgaatc aaaaggagaa ttcttaaaaa aagaatggca
     9901 agatactatt ttggaattat ttcgctattc tgctgatttc tttttttata cagacacaga
     9961 tgcgctctta gtcgaacaaa taaaccgtga ttatcttgat gctactgaaa tcaacggtat
    10021 ttttctatct ttagatgctg attttgatac gacaacgtct gtattcgttg gttctttcca
    10081 ttcacctggc accgacctcg tccctttgtt tgctgaagaa agaaaaattt ttttaacaga
    10141 gcaaaacaat ctttatactc acagccgtac tttttctatg caagatgtgg ctttacatta
    10201 ctatacaaaa gatactgtaa aagatagtaa gttgatcaaa agttacatag aactgatcaa
    10261 acaaaatgaa atggaagtga tcattcaaga attatggaat gaattaggca atgtcagctc
    10321 tgctgcaaaa acactgtttc ttcatcgtaa tactctaaaa tatcgaatcg aaaaatttca
    10381 agaacagtct ggtttcaatc taaaaaaagc caacgattta ctgttttgct atcttttatt
    10441 gcttcatgaa cataattaaa gatagattaa aggggttgtg acaataattt tgtcacaacc
    10501 ccttatttcg aatgaatagt gttcaaaagc tagtttctct tacatcattt tttcaacaaa
    10561 atgcattagc cggtctttta catcttcggt tgaatctttg attgaatcac cataaacaga
    10621 gattttcttt tttcctgatt tgatttttgc taacattccc atcaaagaat ccaagtcact
    10681 atctgaaaga ccatctacga tttctagtaa tttttcattt ccatcaaatt tgtcatagac
    10741 gaattttttt actttcgtcc gagtagtcat atgatggatc ttttccatta cttttcccga
    10801 tacaacgact gctgtcgcta cactggcagc ggctgctacg cttaatccga ttgttacttt
    10861 tgttgatgtt ttcataagta tcagctcctt tttatctatc tccatcatag catagacaaa
    10921 aaaataaacg aactaatcca ctcagtgaaa tctcaatcct ttagggaaaa agttctttac
    10981 tgttcctttt acttgtttcc caaatccgac aggtatctta tctaatacta gcaaaaccca
    11041 tccttgattc ccatcacgtt gaaatgtttc tcctgctgtg taagattgcc attccttttg
    11101 agtgatcggc aagcaaggta tattctctat cttttttgta gcaagcgcta atgcatagct
    11161 aggttcaaat cgattctttt tgaaatctcc taaatgcaaa cctgtacgta cgacttttaa
    11221 accatcgaga gaaggggcta actcaggaac ttcccaaaga tggtcgttga acactaaaag
    11281 tcttccagta gcttcataat gaaaatcatt tgaaaactcc gtccagagtt tttcctgctc
    11341 ttttgtcatt tgcactttac ttttttttcg tgtcttcttt tctttatgca tctgattttg
    11401 tccatgaaaa gtcagctttg caacaaaatg tccttcaccc tgatctttat gaggccatat
    11461 acgtattgtt ttttccaaac cagctacgct tccccattca gaacgtcctg aactaacgga
    11521 ttgagtcaaa ggaatctcct caatcgttac tggataattt tctacaagcc agctaatgat
    11581 ctcttcattt tcttctggtg caaacgtaca agtcgaataa atcagttgtc ctttattttt
    11641 tagcattttt attgctgaag acaaaatctc ttgctgacgt ttttgacagt atagcggaga
    11701 ttcttctgtc cactctttta ttgcatttgg atcttttcgg aacattcctt ctcctgaaca
    11761 aggagcatca accacgatcc gatcaaaaaa gcccgaaaaa tgagggacaa gttctgcggg
    11821 tgcatgattt gtcactattg cgttcgaaac tccccatcgt tctatatttt ctgataaaat
    11881 cttcgcacgt ttcggaaaga tctcattcgt cactaataac cctttcccct tcatttgagc
    11941 agctaattgg gttgatttac caccgggagc cgcacacaaa tccaaaactt tttcaccggg
    12001 ttttgctgca gcagctgttc caacgatcat tgcacttggt tcttggctat attcataccc
    12061 agcttgatgg aggaaagact ttccattgac agtgccaaga aatccctcat tgctgtaggg
    12121 agcgggttgt aattcttcgc tatggtaagt ttggaccatg tccaatcctg ccggttttag
    12181 tggattccac cgaaatcctt ttttcacgct tccttgttca agcgcagaaa aaaaatcgga
    12241 tgcttcttcg cctaaaagaa gacgatattt tttgataaat tgctgtggta acgttgtcgc
    12301 ttcctccttc attccaatgt ttcgttagac attttacaat cttttttacg aaaaataaag
    12361 gtggctgatc tactttttca tgttgctgcc taaggtgact gttcctttaa gatattttcc
    12421 aagtattcat ccgtcacctc gtttttatcc caaacagcgt tcatcatttc aagaaaatct
    12481 tgagaagaat catctgagcg caaacttccc aatgcattaa gccataccaa ttcaagcgac
    12541 ttttcttctt tgatcttcgt gtgacctttg acatatgaga aaaatggccg cttaaatagc
    12601 gaatccatgt ctaaatcaga ttttgcaatg atttcacgaa tactttcatg gatagaaaaa
    12661 aaatctttca ataagtagac aatgcttaaa acatcatcgg aactgcattc agctaagtag
    12721 ttttcaaaat aaacagtgat ttcttctaat atcttctctt ttaacccgct gattgatttg
    12781 aaatgtgtat aaatcgggta tgtagaacaa ccgcagaact ctgctaactc tcttgcagta
    12841 attgacttca ttccatattc ttccacgtat accatacttt tgaacagcaa atattcttta
    12901 ctataatttg ttactctccc catcattctt acctccgtct cttttcatct acccataaat
    12961 aaataacata aataattcta aaaatattat tgataattat caaaacatat ttagttatat
    13021 ccattaaaaa tcaatttttc cgccttaaaa acaagaatat cttgacaaaa taccctagga
    13081 aataaacaat agaataaaca aggtaacaaa aaaattaaat aacgttatat aaaaaagaag
    13141 gcgacactct gtgagaataa cacagactga aatgactttc cactcacagt ttttgtctaa
    13201 ctatatacaa aaacagaata aaaaggaggt atttatgcta attgaagcaa gaaaaaaaga
    13261 gttacttgtt ctacaaatgg tcattcaaaa aaataattgt tctttacaag aattatccaa
    13321 tgacttacat attccaaaac ggacaatcaa agaactgatc cgaaaaataa atgtatcact
    13381 caagcaattt ttattgattg atgaatttat ttattctaat cataaaggag agatccaaac
    13441 caaagaaacc gatcaaacta aaaagttagc tgttttttct aagttaaaat tatgctacct
    13501 aaaagaatcc aatcgtttta actatttgat gttactaatc aattatccac aaactgctgt
    13561 accaaaaaaa tatttacttg aacaacttta tatatcgccc tcctatctcg aaaaactgac
    13621 aaaacagctc aatcattcct taataaaatt ccatttacgg atcctatctg taaaaaattg
    13681 ctgtactctt gaaggaaatg agttatctat ccgtctctat ctttactttt ttctttcaga
    13741 tacatttgga ggtaacgatt ggccattttc ctcacttgaa ttaaatgcac taaaaatgaa
    13801 cagtacagat gagcaaatag aaaaaatttc aaaacaagaa aaaaatatct acttgctgtt
    13861 aactttattc atattacgaa acaaacaaca ggcatatttt ccaaaaactt cttctgaaat
    13921 cactgaattg atggacttat tgcagcatac acatgattat tcagaatact ttacttcttt
    13981 ttcagtgagt cgcccttgtg aagagacaga aacagagaga gcctacttta attatttttt
    14041 ctattgtttt tttccaaatc aaatctcttt tcgacaaaaa caggagattg gttttttatt
    14101 ttccacaagc aaaaacctta tttgtcgaca agtcggtcaa ttgatgactt acttaactca
    14161 acagtttcct ctcaaccatt tagaaaataa aataccaatt tatttttatt ttcttgtgtt
    14221 ggcagttgtt tttttcgaac tgttgggtga atccagcagt agtttttcta cactttgctt
    14281 tccagaagcc acgtccaatc attctagttc ttttatacag gaaaagaaat taagagaaaa
    14341 aatcgataca attttttcaa aaaatgggga aagaaaccaa atcagtcaat accttagtca
    14401 attgatccaa cacttactac aaacagaaac gaaagagcag ttactcatcc atttgcagat
    14461 aaccaaacag tttacaggaa attatcatct tcaaagccat ttgcagcagt tatttcgcaa
    14521 agatgctgtt aaaattaccg catattcaga acatgctgat ttgatcatta cagatcagca
    14581 tgagaaaatt tcagatgaaa cggagacttt ctatctggat acaacgcaca atacagtgtt
    14641 atttggcaag ttaataaaag cggttcatga actgtatatg aaaaaaggtt atgagaacaa
    14701 aacaaagagg atgtgacaaa attcttgtca catcctctta ttccaaataa atggtattca
    14761 atcagctaac tctcggtatt agctcagatc aaagcgctga tttcacaact tctttatttt
    14821 aatctcttcg gttgccgccg aacaataaga tcaagcgcaa cagctgcagg aatgtcgaaa
    14881 gcgctgctgc aacataagtc agtgctgctg caaataatac gtgtcttgcc atcggtactt
    14941 cttcttccgt cagtagtccg ccttcactca aaatttggat tgctcgccga gacgcgttaa
    15001 attcgactgg taatgtcacc aattggaaaa gtaatgctaa agaaaaagcg aaaatcccga
    15061 tattgattaa cgtagagttc cagctaagca atacacctac cataatcaag gggaacgaaa
    15121 tcatcgaacc aaagttagct gctggaacaa gtgctgcacg aatcttcaat gggacataac
    15181 ccgaagcatc ttgtaccgca tgtccgcatt catgagctgc tacacctatc gcagcaactg
    15241 aagtagactg tgcagttgct tgagacaaac tcaacatctt attacctgaa ttgtagttat
    15301 ctgtgagatc tccggcaatt tgttgaacac cgacattatt tatctgttga ctttgtaata
    15361 tatattgtgc tgcttgtgta ccagtcacat tgtttttgct tctcacttga tcgtattttc
    15421 ggaaagtact attgacgtac gctgacgcaa ttccggaaat aactaatcca agaatgacca
    15481 aaagaaatgt cggatctaaa aaaccataca ttccataacc atacattttc gtttcactcc
    15541 ttttcgttta ctttatttta tcattagtag taggaaaaga atgtgaaaag accttgaata
    15601 ttctttaatt ctttttcaca aattccgatt tcagtttcat cggtccaaat ccttctacct
    15661 tgcaatcgat attatgatcg ccttctacta aacggatgtt cttgactttt gttccttgtt
    15721 taatggcacc tgacgcacct tttactttca agtctttaat cactgtcacg ctatcgccct
    15781 ctaacagacg gtttccattt gcatctaata ccactaatcc gtcttctatg acagtttctt
    15841 gttcttcttt gttccattcg ttcccgcatt ctgggcaaat caacaagcct cgatcttcat
    15901 atgtgtactc tgagccacat tctgggcaat ttggtaatgt catcttcttt ctcctttaaa
    15961 atctttagtg agcactattg taacggaaaa agaagatctt gaaaagatac atttgtgatt
    16021 tttactacaa aaggcacgtt ttcgaacgaa gtatcattct gtttttctgc tcttatacga
    16081 ttggcatata tcttggatct ctttatagat ttcctctact tctgctaaat cttttgcatt
    16141 cgcaccactt gctaatggat ggcctcctcc atgatggcgt ttagccaatt cattgatgat
    16201 cggcccctta gaacgtaaac gtacgcggta ataccctgaa ggctgctgaa caaaaatccc
    16261 ccaagccagc acttcgtcaa tcactccagg aagtgaaacg atcgaagctg tctctgaatc
    16321 atcgattcca tatttatcaa gaatttcttg cggaaggatt attcttcctg caccattttc
    16381 atccacctgg atattttgat aaagataacc ggaaagttta gcgactttca tcggcatttg
    16441 ttcaatctct ctgttcaaag cacttgcatc aaatggataa tttctcaata tcgaagcaat
    16501 ctctaatgta cgggacgtcg tggagggata caaaaagcgc cctgtatctc cgacgattcc
    16561 tgcataaagt aaccgtgcag ccttaacgtt catctttaaa gattcaggaa acatcaaagc
    16621 aaattctgca atcatctcac tacagctact tgcttttgta tttacccaca caagatctcc
    16681 ataagggtca tcattgggat gatggtcgat tttgatcagt ttttctgcca actgatatct
    16741 ttgatcactg attctgggtg aattagctgt atcagtcacg atgactagcg ctccttggta
    16801 gaagacatct tcaacttctt gcatttctgc taaaaagcga agcccttcaa tcgtttcacc
    16861 tacttgacgt atttcttttt ctgggaaact ttcccgtaat agttcggcta atcctacttg
    16921 tgatcctaat gcatcaggat cagggcgcaa atgcctgtgg ataatgattt tatcgtattt
    16981 ttttattgta tctactattt cttgctgtac tgtcatttca ctcctgcttt ctaagaacgt
    17041 tccattactt gacaaacaac gattgctttg gaaacgatgg tgttttcaat aaacacttcg
    17101 atatccagtt tagcggaacg tctgccgatt tccaatacac gtggacgaat gtctaattcg
    17161 ctttccaatt ggatcagccg caaataatgt aggttcactt gttcaatcaa gatatttcgt
    17221 ttttggttca tcaccattgt tttttgtgcg acatcagaaa tgatttcgct aagtacgcca
    17281 aaagaaatgg ttccaacgcc attgaccatt tgtggtgcta ctacgaattt gaacttaggg
    17341 ttttccaaac gatttccttc acggtcagta tcaatcgtat ggatatttcc agatatctga
    17401 tccgaaatcg tatctgcaat ctgcggttgt cgctggacaa gctgcatcgc tttcattaca
    17461 tcttgccggg taatcaagcc ttccaatgtc aagtcatcgg aaacgaccgg catgacttct
    17521 agcccatccc agatcatttg atggctaaca gaggcaatac tcattgtttt ctttacactg
    17581 attggttctt tcgtcatcac ccgatcgatg atctggtttg gcgatttccc taaaacatct
    17641 tttgccgtaa caatccccat caaacgatga tggcggttga cgactggaaa acgcgaatgc
    17701 tgcgtttctt ctgacaaacg ctgataatca gaaatcgtat ctgtctgctg caaataatga
    17761 gtcttttcag ctggcatata gatatcactg acaagcatga tatctttttt gatcaattgg
    17821 tcgcttaacg ctcggttgat catggttgcg actgtaaatg tatcataaga ggtgcgtaag
    17881 atcggcattt caagatcatc agctagcttt gcaatctcag cagtcgtatt gaatcctcct
    17941 gtgatcaata ctgcggcgcc atcttccaat gctaattttt ggacttccgc ccggttgccg
    18001 acgatcatta gtgatcctgg cgtaatatag cgttccatgg catgtttagt catcgcgccg
    18061 atgacgaatt tattcaagac cttgtctaat cctgccgccc cgcctaaaac gtccccttca
    18121 atgatcctga cgacctcgcc aaatgtcaaa cgttcaatat gtttttttaa tttgcgttcg
    18181 atacggatgg tccctactcg ttgaattgtt gaaactagtc cgacattttc tgcatctttg
    18241 attgcacggt acgctgttcc ttcactgaca ttcaattctt ttgcgatgct tcttacagaa
    18301 attcgattgc caacaggtaa actttcaata tattctaaaa tcaaatcatg ttttgtcgcc
    18361 attttctgcc tacacttcca gcgtttccga gacgctcatt atttttcctt cactatcttc
    18421 cagtaactct acaaaagatt cgggatcttg ttcaatgaca gggaaagtat tgtaatggat
    18481 tggaactact ttcttggcac gaattgtttg cgcagccttt gctgcatctt ctggccccat
    18541 cgtatagtta tcgccaatcg gcaagaaagc gacatcaata tcgaattctt ctgcaagcaa
    18601 tcctagatca ctgaaataag cagtatcccc tgcatgataa atcgtttttc cttctgcttg
    18661 aataataatt ccgctaggct cgcccatata ctgaacgata ccgtctactt catagcttga
    18721 actatgctgt gcatgtacga attttaccac gccgaatgga aacgcatgtt ttccaccgat
    18781 attcataccg aatgaatcta ctcctctgct gttcgcataa tcagcaatct caacaatact
    18841 gataattgtg gcttgatttt cttttgcaat aggaatcata tctcctatgt ggtcactatg
    18901 accatgagta atcagcaacc aatctgtctt tacttcttct gcagttaagt ctgtcaatgg
    18961 atttcctgta ataaacgggt caatcatcac gcgttggcca ttttccattt caattgttaa
    19021 acaggaatgt ccatgatacg taattttcat attttacacc tcgcgttttc tctgtatctt
    19081 ttttattaaa aacgatttca tcacttgcac atcaatgaaa aaatatagct gctaaatata
    19141 ttttcattgg attgatagta cagtatgtac aaagcaattg taacagataa tacaggatgc
    19201 accaagtacc aagcagatat aatctcaagt ttgaggtctc tgctctgctt agcttctctt
    19261 ctcgtccctt aactaattaa atcagcgtaa ataggatgga cgatcttttc taaatcggct
    19321 acttttatcc gaaggcttct cccgatttca ccgcttgaca caattacttc ttctttttct
    19381 tttaaagaac tgtctgctaa aaaacaataa tcaggatgtg cgagttttat tccaataggg
    19441 gtgtttgctc cgtggggata tcctgtatgc attaatacaa aatccattcc aggaaaacca
    19501 actttacgat ctttcgtcac ttgtctcgtt tttttgtaat ctaagtgatc gttcaaagga
    19561 atcaatgcga tgatcacccc agttttgttt cctttcacta cgagagtttt acatatcaaa
    19621 gctggatcaa tccctctttt ttgtagttct tctgtgaaag attcttctac cacatgacta
    19681 aaatcaagtg gttgatagct gatcttttgt tcttctaaat aacgttcgac ttttgtttga
    19741 ctcatcattg attcactccc tttattctat cgtttattat aaagcgaggg atgctgtatt
    19801 caaaaattat ttgtttttcg caaaaaaaga gcaagacgag cactctatag agaggttcat
    19861 cttactcttt ttgtttattt tttatttcga cgttgagtag cttccataat gactggcaag
    19921 atcactgggc ggcgttttgt ttgttcaaat aagtaacggc ctaattgatc tcggatgtct
    19981 tgctttaatt tgctccactc aaaatcattg ctttctaaat gtttctcaac gattgtttca
    20041 atcatattgc tgctttcttt catcagatca cggctagctt ttacgtaaac gaatccccgt
    20101 gaagtaattt gaggttttga aatgattttc ttttctcgcc gactgatagt gacaaccgct
    20161 acgaaaatcc cgtcttctga caagattttt cgatcacgta aaacaatgtt tccgatatca
    20221 cctatgccta atccatcaat cattacattt tctgcacttg tagttcctgc aacactcata
    20281 cgcttgttct tatattccag cacgtctccg cgtccagtaa tatagatatt tttgtatggc
    20341 atccctactg catgagccaa atctgcatga gcagctaatt cacgatactc tccttgaact
    20401 ggcacaaaat atgttggttt catcaaattg atcattaatt gcaagtcatt aggattggca
    20461 tggccagaaa cgcgcatatt ctcagagatc aacttcactg ttccaccagc tcgataaatg
    20521 atatcttccg ttttcgccac gatggtttcc atcgcgatgc ttggcgtagt agtgatataa
    20581 accaaatctc cttcttcaat cttgacatta cggtgtgtac cgtttgccat tttttgcaga
    20641 gacttgatgg gttcacccat tcggccagtt tctaaaatga tcagttcttc tggatcatag
    20701 tttttcatgt ctttcaacgt aacaagcaga tcttcacttg gtaattgaag tttttctaaa
    20761 cgcatcgctg tgcgaataat tcgttcgaaa tcttgaccag tcaagacaac ttttcgttgt
    20821 gctttttctg ctgcatccaa tacttgttgc actcgttgca aattacttgc tacacaagcg
    20881 acgatgatac gcccttccca atatttgatc gtatcaaata cttcatctgc tatttgggct
    20941 tcagaagcta caggctgagg attttctgca tttgccgatt cacttagtaa ggctaagact
    21001 ccttctttgc cgatttccgc caatcgtgca taatctgttt gatacattgg gatagccgtt
    21061 tggtcaaatt taaaatctcc cgtataaacg atactacctt cttttgtttt cagattgatc
    21121 cccactgaat ctggtatcgt atgagtggta cggaaaaagc tcactactgt ttcaccaaag
    21181 tctatttctg tatgctcatc taccacatgg aaatccttaa atcctttggc tgcttcatta
    21241 cgactgacat tcaattttgc taactcgatc gtcaactctg tcccgaatac tggtacagaa
    21301 atttttgaca acaagtaagg aagtgccccg atcgcatctg catgtccatg tgttaaaaag
    21361 acaccagcta cacgatcaat gttttcttct aaatacgtaa aatcagggat tacgacgtcg
    21421 atccccaaca actcattttc aggatatttt agcccacaat ctaaaataaa aatatcctcg
    21481 cccacttctg cgacatacat gttttttcca ttttcacgaa cgccgcctaa tgggataatt
    21541 ttaatggtac tcacaaactt cacctcttct tatgacatcc aagtttaaag atgtcgattt
    21601 tcttctttat ctaaatatat gagccattcc aatgaagcat atgcaaaatc actatttctc
    21661 aacttatgga gaatcagcag gaaaattacc agcacatccg cgttctgaca gttggatggg
    21721 cattttattt tggatatact tcattaacaa aatggatctt ttgcgaaacg ctatagccag
    21781 aatacttata taagtattca gctgttcccc attattatac aacaaataaa ctaaatcgct
    21841 agtatcagca attgttagaa caactatgca cgtaaaaatc cctctgtagc atctaggatt
    21901 tcttttgcta ttcctctttc atttcttctt cgtcggtttg aaacatactt ttttcatttt
    21961 accacatttt ttgcaataac tatagtgact ttttatatat acagaacctc atgttgatgg
    22021 tgtgcaaaca gcataagatt taagctagct ttaagatagg ttgtctatta tcaaatgcat
    22081 ctactaggag ggatgcaaaa tatgaatttt atgaaacgtg catggaaaag tacaaaagta
    22141 aaatggggac gttcattgtt attgtttgcc gtgttcacag ccattcttat ttttgtgcta
    22201 gctggcctca cgattcgaag cgctgcagaa gaagcagcga atcaagcaca aaaagaagtt
    22261 ggagcaacag tgactttaag tgccaatcga gaagcttcat ttaaaaaaca ggaacaaact
    22321 tcttcaagcg gttctaccac tgaagaacgt ccagatccag gcagtttttc tcttacacca
    22381 gtttccttaa cggacgcgga aaaaatagct gaattagata atgtaaagag ttattccttt
    22441 gaaagttccg cctcagctat ggcaaaagat ggaataactg ccatcactag ttctgattca
    22501 agtgaagaca gttcagaaac tactgatgca ggcggtgaac ctgctggagg aatgggcggg
    22561 aatccgcaaa tgactcaagc agactttcaa atcagtggtg tgtcagcaac tgcacaaaat
    22621 agtaattttt ctgatggaac agcaaaaatc acggatggtg aaggaataga tgacagcgac
    22681 aaaggcacaa acaatgtagt cattgattct actctagcag aaacaaatga cctggcagtc
    22741 ggagatactt tcacaatcac gagtactgaa gatgaagata ccacttatga aatgacgatc
    22801 aaaggaattt atgaatccag cgaaacaagc ggcagtatgg gtatgaaatt caacttcatg
    22861 aatccgtcga atacacttta cacttcttac acttttgcaa atgaactaaa tgggacatct
    22921 gacgataaca cgatagattc tgctatttac actctatctg atccagataa aatggatgag
    22981 tttctcaaag aagctgagaa gctgatcgac acagatacat ttagcttaca atcaaatgat
    23041 tccatgtatc agtcaatgtt ggaaccttta aacaacgtgg caagtttttc taaaaatgtt
    23101 gttttactag tggctgtagc cggtattatc atacttactc tgatcattat gattaccatt
    23161 cgggagcgtc ggcatgagtt aggcgtcttg ctatctttag gagaatccag aagtaaaatc
    23221 attctccaat tgtttaccga agtggctatt tgtatgattc ttgcattagg agttgcttcg
    23281 cttagcggaa acgtcgtcgc gaatgccgtg ggacagcagc tacttgacca acagacagaa
    23341 accacgacac aaaaccagca agctcctggc ggtggacaaa tgccaggtaa cagacaagaa
    23401 caaggcggtc aacgcgatgg tcaacaagga accacgaata atccatttgc tgtttctgat
    23461 caagtcagcg aattggaaat caatgtcaaa cctgcacaat tgggactatt agccggagta
    23521 gcatttggaa tcagtctgtt ttctgtcttt ttagcttcta tagggatatt aagattaaac
    23581 ccaagaaaaa tcctattaaa ctaaaggagg aatttgatgt tacggacaga acaattggga
    23641 ttttggtatc aagatccgca agatgcgctt tataaagatg tagaactgaa tttcgaagct
    23701 ggaaaaatgt acgctatttt aggagcaagt ggttctggaa aaacgacttt tctttcgctt
    23761 atttctggac tagatgcacc aaaagaagga aaggtatact atcaagatcg ttcactgaac
    23821 aaaatcgggt taagaagtta tcgtaaaaat gatgtctcga ttattttcca agcttacaac
    23881 ttgcttcctt atttatcggc tctagacaac gtcatagcag caatggaaat cactaagacc
    23941 aagcaagaga attatcgaca agttgcttta gatcgactgg ctcgtgtagg aattgatgaa
    24001 atattagcaa aaaaacaggt gaccaaactt tcgggaggtc agcagcagcg agtcgctatc
    24061 gttcgtgcta tctgctgtga acatcaacta atcgtagcgg atgagcctac tggaaatcta
    24121 gatgaaacaa cttcacaaga tatcgtcaaa cttttccaag aaatcgccca tgaacaaaat
    24181 cgctgtatta tcatcgtgac tcatgagatt gaagtagcaa aaagctgtga tgaagtcttt
    24241 gaactaaaaa ataaaaaatt tcaaaaaatc gaagtttaaa aaacaggata atgatcaaat
    24301 aaaaaatccg aaccatatct gtctcgcaga tatggttcgg attttttatt tgcttgattc
    24361 aattagtaat aagtggtttt tatttttttt cgtcttttcg agaaaacttg tctttgactt
    24421 cgtcgcctaa atttcgagct ttttctttga tgtcagcacc tagtgattgt gctttccctt
    24481 ctgtttcttt gctcttgtcg tctgttgctt tgccgtatgc ttcttttcct tcaccgacta
    24541 ctttatcttt catatcttta gaacgtcctt ttaaatctgc cattgtgctt cctcctctta
    24601 gtttgtttat tgatctacct tcagggtaac atcaacaaca gatacagaca aacagaacgc
    24661 tcgttttcta aaaaagatag ttagagctgt tgattaaaaa cttttttcga aagtccccca
    24721 tactttgact tctttttctt ggaccattat ttctccttta gcgataactg tatcaatatc
    24781 aagcgtttct ttatccaaga tacacagatc tgcatcagca ccaatttcga tttttccttt
    24841 tttatccaat ttcaatatac gtgctggatt actggttata gctcgtaagg cgatttccaa
    24901 agggatactt tctttttgca cagcttcttt gatccctact agcaatgcct tggcacttcc
    24961 tactcctaac cctaggaaat gattgttttc atcaaaataa ggcaagcttc cttgtccatc
    25021 tgaggtcatc gtgaaattat ctaaagaaac atcttcctcg atcaatcgtt tcagtgcttt
    25081 gctgaagcga acttcaccat ctgtcttctc ccaaaaatca ggatcttcgc tagcagtgaa
    25141 gtcaatcgtg ccaccacgtt tggcaaatgc cacgcaagct tcaaataatt ctggtgtgcg
    25201 atttgcatga gtaggcaaaa attgtgtgat cggaatttct gtttcttcta cgattcgtgt
    25261 caatagctct agctttcttt ttcctccgcc taagtggaca ttgatgatcc cagcttttcc
    25321 ggataacatg cctcctacac gagcatctgc tactgcacga gcgaactctt caaaacttgg
    25381 ctgagaagaa cggtgatcgg atactgcgat ttctccgatt ccgataattt tatcaattgt
    25441 caaaaagtct ttgatgatag aatctgttac tgtttttacc ggcaatcggt acgaaccttc
    25501 gtatacataa gtggagattc cttctgcttc cagacctttc gctttgctga tcaacgcagt
    25561 catatctcta ccttctccgt ctgttcccaa acaaccgaca actgtcgtta caccagctgt
    25621 agtcaattgg ctcaatgtga cttctggcgt tcgattttga taaccgcctt ctcctcctcc
    25681 acctaaaata tggaaatgac agtcaatgaa acccggggtt agtacttttc cctcacctga
    25741 aagttcttct acttccactc cttcgtagcc gccttctagc tgttcttcta cagccaaaat
    25801 cttcccaccg gcaatcagta catccatttt tcctaagtaa tctggtgcaa acacttcaat
    25861 ttgtcgaatg attttcatac atttttcctc tttctttaag tataactgat gataggatct
    25921 taaaaaataa tccaaacgat aggatcttta ctcctttgat tttaccgtaa aatgacggtt
    25981 cttggagtcc ttatctactg tttggattac ttttttattt acaggtctcc agtactactg
    26041 cagacctatt gcaatggcaa tcatgatgaa aatagttcct aaaacaaaca ggaatccttg
    26101 catcttgatt tggaatcttg cccattttgc ccattcgatc cgtgcaacac ctagcacacc
    26161 aatcaagctg gctgatacgg gtgtaaaagc gtccataaaa cctgaaccaa gctgataagc
    26221 aagaactgct acttgtctgg atacacctac taaatctgcc agtggagcca tgattggcat
    26281 agtcaaagct gcttgtcctg aatttgatgt aacaaccaag ttgaacaaac tttggaagat
    26341 gtacatcgcc caagcaccaa tgacagctgg aacaccggtc aacgccgtcc cgatcccatg
    26401 caaaatcgta ttcaaagctg aaggaacaga tgcatcagat cctcccaaga caagaagaat
    26461 ccctttggcc atacctacta cgattgctgt accagctaaa tcagctgcac cagattggaa
    26521 agaagaagcg atgtcattga ctttcattcc atctaatttg aaaagaacag caatgattcc
    26581 agcaactaat cccatcacaa agaattgaga agcgatttct ggaatgtaat agcctttttg
    26641 agtcacgccc caaacgatcc agacaaggac aactaacatc tctaataaga tcaatttatg
    26701 cccaagcatg aattttttat tttcatcaga tgtctttttg atatgagaac ggaaataatc
    26761 atctgatttg taagtcaacg aactttctgg ttttttacgg attttttctg catatatcat
    26821 catataacca gcggctaatg cagtaacaac tacccacata atcaatcgga atgtcgcacc
    26881 agacaacacg gggattccag caatcccttg agccaccgct acgctaaacg ggctcatcca
    26941 agaggtcgca tttccgactt gagatgcgac ataagtcacg gttactgcta cgatcgagtc
    27001 atatcctaac gcaatgacaa atggaaccat caccattgag aatggaatta cctcttctgc
    27061 catcccgaat gtagcgccac cgaatgaaaa agcaaagaat aatagcggta aagctaaacg
    27121 ctccagtccc ttagttttac tgataaacgc atagatacct gcgtcgatcg ctccggtacg
    27181 cataataata ccaaaagcac ctccaacaac aaggatcaat gcagcgatcc ctacagcaga
    27241 tccatactta tctccagata ctagtccttc aaaaacaaaa tttaagaaac caaagccgcc
    27301 aaaatcatct gttccccata ttttggctgt tttatgcaat tttttagaag tatcatagat
    27361 attttcgccg tactgatcgt aaagcacatc atctgtcaag gagatttcat ctagtttttc
    27421 ctgcgtaaga tttttttctc cgtcagcaat gactttttcc aatccttttt ccggaacatc
    27481 cagtttttca cgttctgctg gatgatcttg cagttcttct aattgatcaa acacatacga
    27541 cttatccagc tcgtaagcat aacggaagga atcttgacgt aaaacagtac gagtacttgt
    27601 ttcgccattt gcatctttgt attcaatatc ttgcgtgctg aactttcctg ctggaacgac
    27661 aaaagtcagt atccatgcaa agatgactac accaaaaata atgacatacg tatggggtgt
    27721 cgataattta gtgaagtcgc gtttcggttt tcctgaagaa tttgttttct tcaaatttat
    27781 ttcttccttt cttttttcag taattttgat gaataaaaaa tggataatca aatgaat
//
LOCUS       DACGEU010000033        27232 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.033, whole genome shotgun sequence.
ACCESSION   DACGEU010000033 DACGEU010000000
VERSION     DACGEU010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27232)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27232)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27232
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.033"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(161..445)
                     /locus_tag="IXR40_001310"
     CDS             complement(161..445)
                     /locus_tag="IXR40_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361168.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            complement(463..1353)
                     /locus_tag="IXR40_001311"
     CDS             complement(463..1353)
                     /locus_tag="IXR40_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HAQ4361169.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFALDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            complement(1373..1591)
                     /locus_tag="IXR40_001312"
     CDS             complement(1373..1591)
                     /locus_tag="IXR40_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361170.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            complement(1561..3261)
                     /locus_tag="IXR40_001313"
     CDS             complement(1561..3261)
                     /locus_tag="IXR40_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HAQ4361171.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            3528..4301
                     /locus_tag="IXR40_001314"
     CDS             3528..4301
                     /locus_tag="IXR40_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361172.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            complement(4382..4951)
                     /gene="thiT"
                     /locus_tag="IXR40_001315"
     CDS             complement(4382..4951)
                     /gene="thiT"
                     /locus_tag="IXR40_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HAQ4361173.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     regulatory      complement(5017..5119)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(5125..6096)
                     /locus_tag="IXR40_001316"
     CDS             complement(5125..6096)
                     /locus_tag="IXR40_001316"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HAQ4361174.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(6190..7563)
                     /gene="glmU"
                     /locus_tag="IXR40_001317"
     CDS             complement(6190..7563)
                     /gene="glmU"
                     /locus_tag="IXR40_001317"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HAQ4361175.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(8066..8884)
                     /gene="purR"
                     /locus_tag="IXR40_001318"
     CDS             complement(8066..8884)
                     /gene="purR"
                     /locus_tag="IXR40_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HAQ4361176.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            complement(9051..9875)
                     /locus_tag="IXR40_001319"
     CDS             complement(9051..9875)
                     /locus_tag="IXR40_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HAQ4361177.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(9848..10528)
                     /locus_tag="IXR40_001320"
     CDS             complement(9848..10528)
                     /locus_tag="IXR40_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HAQ4361178.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(10551..11489)
                     /locus_tag="IXR40_001321"
     CDS             complement(10551..11489)
                     /locus_tag="IXR40_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HAQ4361179.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(11734..12585)
                     /locus_tag="IXR40_001322"
     CDS             complement(11734..12585)
                     /locus_tag="IXR40_001322"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HAQ4361180.1"
                     /translation="MELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADHLFFE
                     EITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAGLGGG
                     STDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQVLPS
                     MPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMGNSLE
                     DITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGFCEEV
                     YLVRTLQ"
     gene            complement(12739..15312)
                     /gene="mprF"
                     /locus_tag="IXR40_001323"
     CDS             complement(12739..15312)
                     /gene="mprF"
                     /locus_tag="IXR40_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HAQ4361181.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLP
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            15453..16259
                     /gene="proC"
                     /locus_tag="IXR40_001324"
     CDS             15453..16259
                     /gene="proC"
                     /locus_tag="IXR40_001324"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HAQ4361182.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLTDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            complement(16338..17894)
                     /gene="rny"
                     /locus_tag="IXR40_001325"
     CDS             complement(16338..17894)
                     /gene="rny"
                     /locus_tag="IXR40_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HAQ4361183.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(18305..19354)
                     /gene="recA"
                     /locus_tag="IXR40_001326"
     CDS             complement(18305..19354)
                     /gene="recA"
                     /locus_tag="IXR40_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HAQ4361184.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(19463..20704)
                     /locus_tag="IXR40_001327"
     CDS             complement(19463..20704)
                     /locus_tag="IXR40_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HAQ4361185.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(20944..21522)
                     /gene="pgsA"
                     /locus_tag="IXR40_001328"
     CDS             complement(20944..21522)
                     /gene="pgsA"
                     /locus_tag="IXR40_001328"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HAQ4361186.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(21731..22615)
                     /locus_tag="IXR40_001329"
     CDS             complement(21731..22615)
                     /locus_tag="IXR40_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4361187.1"
                     /translation="MAFETIGEKLRQARLNKKISLDELQQITKIQKRYLEAIDNDDFD
                     QLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQPETVSTSRKAMHQ
                     EESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDTASSLKVEGSVEES
                     SSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITDATKPVTLEFTAVN
                     RVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNATIKANGESVPVNP
                     GENNQSPKNVNLTLQYAE"
     gene            complement(23392..24678)
                     /locus_tag="IXR40_001330"
     CDS             complement(23392..24678)
                     /locus_tag="IXR40_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HAQ4361188.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(24671..25939)
                     /locus_tag="IXR40_001331"
     CDS             complement(24671..25939)
                     /locus_tag="IXR40_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HAQ4361189.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYPDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            26191..26652
                     /gene="mscL"
                     /locus_tag="IXR40_001332"
     CDS             26191..26652
                     /gene="mscL"
                     /locus_tag="IXR40_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HAQ4361190.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(26711..27157)
                     /locus_tag="IXR40_001333"
     CDS             complement(26711..27157)
                     /locus_tag="IXR40_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4361191.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGQ
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
BASE COUNT         7741 a         5873 c         4723 g         8895 t
ORIGIN      
        1 taataccgag aaaatggttt ttgaacatca cttattcaaa ataaaaaaag attgtgacac
       61 gaattttgtc acaaccttta aatgtattcc tagagcaaag aagctaagcg aagaaatcca
      121 attctgatta tttattgtat ttctttgttc agcatccttg ctaaaagccc atattggaca
      181 aagtattcac tacacccatg atctcatctt ttcgagaacg tgctttttct gtcggatctt
      241 ctacctcttc tgtgtcaatt cgaacaataa atttccgatt catcgtcacg taagcaccgt
      301 cgttgatcaa aataaacagt tcgttctcat tatagtctgc acaggcatct ttccatacgt
      361 caaagccgtt tttttcagaa gggatatccc gtttaaccac agtttttcca cttaattcgt
      421 ggaacgttac gtcataatat ttcattatct ctacctcttt cgtcattcaa tattttgtac
      481 ttgttctctg attttttcta agatcgtctt agactggacg acttgatttt taatttcgat
      541 tgcatttgat ttggaaccga tcgtgttgat ttcccgattc atttcttgga tcaggaaatc
      601 taattcccga cctacaggac attgtgcttc gataagttca tctagttttt gtacatggat
      661 cgccagacga tccagttcct cgtgaatatc tccgcgttcc aacaagatgg ctagctccgt
      721 caacaaccgt tgctcatcga ctttcgctcc aagaaattcc tccagctttt tttgatacct
      781 tatttgaaat tccttttcat agatttctac aaaactatcg agttttttta gtacttcttt
      841 gaattcttca gtattctttt tcaacactaa agctaaagct tgaccttctt tttctcgact
      901 cgcctcaata gaatcaagtg cgcttttcaa tgtatctaga gctaactgtg ccaattcttc
      961 catgctctct tccggttttt cttctaccgt tacgaagttt tcgtccagcg cgaagcgttc
     1021 cgccatccga ctaattgaca cttgattttg actaccgtat cgttgttgaa ttccgtctgt
     1081 caattgagtg ataagtgaat caatcaattc ccagttgatg acgatctgtt tttcgttttt
     1141 gccaatataa gctagattca caaatacttc gattcgaccg cggcttaact gctgtttaat
     1201 aagctgacga aaatcgtttt caacaaagtt caggatttta ggacttcgta tttgaacatc
     1261 tagaaaacgc tggttgacac tttttatttc aatatctaac tgatacgctt ttgtttcgcg
     1321 gatggctttg ccaaaaccag tcatactttt cattcgacag ggtccttcct cattacatat
     1381 tttctattgc tttttgcagt tgttcaaact cttcgttcgt caatgtcagg cctttcccca
     1441 ttttttcatg gtctggcgcc caatctcgaa gatcgaattt tggcgggcga ccattccagc
     1501 tgactaggtt cagttcttta cgccacccct tgttgttttc tgacaatata gcgatttctt
     1561 ctacgatttc atatgaaaat tcttgtgcca tggttgttcc tccttgagat aatataaata
     1621 taggatcagt aatgtgtcaa ctggttgctt aagcaattca tgctgcaaac gatccttgcg
     1681 ttttccttgt agcagataat caaaataaac agttttcgtg cgctcatttt gtattttttg
     1741 ctggtatttt cgataccttc gccattcttc agtacttaat tgaccaattt gtgccaataa
     1801 atcatccggc atacttttta tatcttgttg gcagatcatt tgaatcatca tgtctacttg
     1861 atagatttca ttgggcagta aaaaatgttt ttttgctaaa agttctagca tcgccaatcc
     1921 gcatgtctct ggtacgaccc tgttcttata taaattacgc agtttttgcc aaaattttat
     1981 gcttttgaaa aaagataatt ctaactgaat ttcttttgtt aagtaagaca aaaatcctcg
     2041 ccagtatgtt cttgcaggtt taacagaatg aaatgtatac cagttcccat agtaatagcc
     2101 taatcgtttt ttcatttcca gatagcctaa ttgtaaattt aattggttcc tttggctatc
     2161 aaaaagcaga aagctgccta gtgtccacaa tgtttgacat ttccaatgga taaaaatgtc
     2221 tggcatacga atttttttcg ctgggcctgg cccttgcaca tctacgacaa atgcctctgt
     2281 tgctcctttg ttaatcgcaa tatcaatagg tattttgttg cgatacccac cgtctgcata
     2341 tttatttttt ccgatctttc gataagccat agcgggataa aatgaagcag aggcgagtat
     2401 ccaatctggt atttcttctg tttttgtctg ttggatatca gtcactactt ccgctagttc
     2461 tggcagttta gtagacaccg tatataaacg tattttggga ttatgtttga gtaaggacaa
     2521 atccaaattg tctttgacca tcttttccaa tggagcagaa gaaaccccgc cttcaattag
     2581 tgctgttttc gtcatttggc gtctttctcg atagaagcgt tcacgaaggt cttcaactgc
     2641 agccatttct ggtaacgcaa gcacttgtct tgtcgacagc tttttccata aattcacagc
     2701 ttttttcata tctccttgta aaatcaatgc gccgttcaac gcacctaccg aggtacctgt
     2761 gataatctca aagttgatat catgttcctt cagcgcctgc cacacaccaa tctgataagc
     2821 accgtgcgct cctcctccac ctaaaacaag tgctgtatga tagaccagct ttttatttaa
     2881 ttgtgtggtt ccttgatagc cgtttttatg aaaaatacgc aaccattctt ctgatagagg
     2941 agattgaaat aaaaaacaac agttttcttt aataaaaaaa cgagcgcaag cttccatata
     3001 ccgaaaaaat tttttccatt caaaagtttc accttcaatc aacagattat taaaaataac
     3061 atctcctcta cttttagcaa tagtaaaata gacggtatat tttttcgata ctgctttaaa
     3121 agcacattgc ttttttgcag aacgccaaaa agcgtctcta ctttcttgat gactttgaaa
     3181 aaatggaagg ggttgttttg cttgctggat aggcgaatac agcgacattt tctgtgaaaa
     3241 gtaaactttt tttatctcca tcgcgctctc ctttttcttc aagtatacca gtacgtcata
     3301 aaaaggtcat gagtctcgta ttcgactttg tagattccat aagaaaacaa ttcataaaac
     3361 ctcctttaaa taaaaaaata caaaaatcac aaaaattaat tgaaaatgag agtgttttca
     3421 atgaaaacgt gattttgtaa tggaatttta aaataaaaga aacaagcttt tttaatgcaa
     3481 atgttgtaaa ataaaagaga ttaagaggaa ataagaggag gaacatgatg actgagtcag
     3541 tttatgtaca tattgatacc acaagtaatg ctgttttaac aaaagggctg actgctactg
     3601 actttgcaaa cagtatcgtg cattttcctc aaaacttgct cttgcttgat ccatctgctt
     3661 ctgctggaga atatgaatcc catacagggc tgaaagtaat ccgtggtaca gaaaatattc
     3721 agcgtttctt ttcctcttct cgtaacaggc gtggattcga tgaattgaag tggatcgact
     3781 ttactgattt aacgatgctg aaagaattga cacctttaga aatttcagaa ttattatatt
     3841 ttggtcatat gaaaacacat cttcattcgc cgttttttta taaactacag aataattttg
     3901 tatacttcga tcttaatgat cagctgaatc ggatttatta tcgctattta gatgaatttt
     3961 ataggatttt tgctagtaaa ttaagttcga tcttgtcaga taagatcaat gtaaaaaaat
     4021 cttttttcaa aaaagaaaca cctgttgaaa aaatcagtgt ggaattattg aaagaaatgc
     4081 gtaatttgat gcaggaaggg atcatttttt cttttgatca agttggtttg atcgatggta
     4141 aatatcgtat cccaatctat gtgattgaag attatatttg gaaattaaaa ggcacccggt
     4201 atcgagaaga ggaaatcatc gctactttaa tctactctgt caccgatcga cactggcaat
     4261 tggtagaaga tgccgatctt tcttatctgc cattgaagta gatctatttc ttatcaaaaa
     4321 ataaaaagga aacaagaaac taggacatga ttctgtctca agtttcttgc ttctttttta
     4381 tttacagctc ctgtcgttta tctggcacaa aaatcgaagg agtcgtttgt tggatcccta
     4441 ataaaacgat gatcgttaca atagctgtac tcaacccgct ggcaccattc attacgaaag
     4501 aaaagagcca aggattcatc ccccatagtg catacgctcc ccagaaaacc actcctgcaa
     4561 taaaatgcca aaaatatctg gaaagtgcgc caatcaatgc accaaacacg atgctttttc
     4621 taatttgttt cgtattatcg tctacatagc ctttttggac atttgaagcc atgagccctg
     4681 ctgcgcctgc aaaagtatag gcaatcgggt actcaatcaa cacttgaacg acacttaaat
     4741 aataaacttg tcccaacgga aaatgtagga tgccccaaat gaaacctgcc agcatccctg
     4801 cctttgtccc tcttcttaac gcaaaaagag tcaatggaat ctgccctaat gaaatagaaa
     4861 aactgctgcc gatctggatc ggaatcaacg acaacaccat cgctaacgct gcaacaatcg
     4921 ttccttctac ccaaactcta ttttttccca taaaaaaact tcctcctttg aataaaaaag
     4981 tcacaaagga ggaagcagct ttcgaaaata gtcaaacagc tgtttattca caattcctac
     5041 gctcgcataa ccgatacagg tacgaagggt ttagaaatag attcaatctc agcccaattg
     5101 gactcccctt tgtgagttta tttattattt attttttgtt tcaaacaatg gactaactgg
     5161 tttgttttca tggatacgtt tgattgcatc tcccattagt ccgccaacac ttacttcatc
     5221 gattttgtcg attttacgat cttctggaag atagatcgag tctgtaacaa ctagacgctc
     5281 gatagctgaa tcttctattc tttgtaaagc agggccggat aatactggat gtgtacatga
     5341 agcatacaca ctagttgcac cagcttcttt caaagcattg gcagccaatg tgatcgtacc
     5401 tgctgtatcg atcatatcat cgatcagtac acaagttttg cctttgactt gtccaatgat
     5461 attcattact tctgcaacat ttgcttttgg acggcgtttg tctatgatcg caatcggaga
     5521 tttcaaaaat tccgctaatt tacgtgcccg tgtgacacca ccatggtctg gtgaaacaac
     5581 gacaacatca tcgcctttga ttcctttttc taagaaataa ttggcaataa gtggcgcacc
     5641 catcaaatga tcgactggaa tatcaaagaa accttggatt tgaactgcat gaaggtccaa
     5701 agtcagcatt cttgttgcac cagctttttg aatcatgttt gctactaatt tcgctgtgat
     5761 tggttcccgt gcacgtgctt tacggtcttg acgcgcatag ccataataag gcatgactac
     5821 gttgattgtt tttgcacttg ctcgtttcag tgcgtcaatc atgatcagca actccatcaa
     5881 gttatcattg actgggctgc tcgttgattg aataacatag acatgcgatc cacgaatact
     5941 ttcttcaatg tttacttgaa tttctccatc actaaattga gtaacagatg attttcctaa
     6001 ctcgacgccg actgctgctg caattttctc tgctaatggg cgattggaat ttaacgcaaa
     6061 aatttttaat cttgggtcaa agtaatgttt tgacatgggg acctccactt tctttttcac
     6121 aactctagaa ttctacctaa taaatagtag tcatattttt taaataaatc aagtgatttt
     6181 gcaaaagtct tagtttagat aagggagttt ttttgcatat ccttctttat tgacttgtct
     6241 tgctctcgca attgccagcg catattctgg aatattgtct gtaattgttg acccggcagc
     6301 aatcgaactg tttttagcta cctcgacagg tccgatgata ttcgtgctag aaccaataaa
     6361 gctgtggtcg ccgacagtcg tatgatgttt gttctttcca tcatagttga cgaagacaac
     6421 accacatccg acattgattt cttctcccag cgtagcatca ccaacataag tcaagtgacc
     6481 gactttagtt cctttgccga tttgagcatt tttcacttcc acaaagtttc cgatatggac
     6541 gttttcgcca atttcagctt ttggtcgtaa atgtgcataa ggtcccacat ctgcatgttt
     6601 cttgacatgg ctgctttcaa tgactgagtt ttcaatgacg acgtgatcct caatcctact
     6661 gtctacgatt tttgaatgtg acccgatgac acaatcagaa ccaatgactg tatttccttg
     6721 gatttgtaca cctgcttcga tcaatgtgtc tggaccgatt tctacgcctg catcgatgta
     6781 tgtcgttgct gaatcgacaa agcttacgcc attgaccata tgcatctggt taattcgctt
     6841 tctcatgatc tcatttgctt tagctaacgc gatccgatca ttgactccca ttgattcttc
     6901 aaaatcatcc gtttgataag cagcaactgt atggccttct tcttttaaga tttcgatgat
     6961 atctgttaga tagtattcac cttgagcatt gtttgttcca actttgctta acgcatcgaa
     7021 caaagcttcg ttgtcaaaac agtaagttcc tgtattgatt tcttgtacaa gagcttcttc
     7081 tggtgttgca tctttttgtt ccacgatttt ttctacgatc ccaatatggt cacggatgat
     7141 tcgtccatat cctgttgggt tttctgcttg tgccgtcaag atcgttgcac ttgcattttt
     7201 tccttggtga tattcaaaaa gattgttcag cgtttcagta gtcaataatg gtgtatcgcc
     7261 actgataact aacgttgttc ctttttttcc ttccaagaaa gaagcagctt gcaaaacagc
     7321 atgtcctgtt cccaattgtt ctgcttgtaa cgcatattta ctgcgttctc ctagttgtgc
     7381 tttaacttgt tctgctccgt gtccaacgat cgtaatcact tcatctggtt tcgtttcact
     7441 gacccgatta atgatatgtt ctaccatagg tttaccagaa acgggatgta aaactttata
     7501 taattttgac ttcatgcggg tacctttccc tgccgccaaa ataattgcat aacgtgcgtc
     7561 caactgcgtc actcctaaat atagtttgct gatttcagtt tatcccagta tacccatttt
     7621 ttcaacaaaa caagtgattt tcttttatcc cagcgttttc tggataaaaa aatagataga
     7681 ccataacggg cctatctatt tggtaaccgg tgctctcctg ccaactcctc ggtcacaagt
     7741 cacactactc ataaaacatg aaaagctgtt ttttgaaatc gtttcttgtg acttagagtt
     7801 aaacggtagg cttacaacct cttcattaaa cgtttttcaa tcagctgacc ttcggtatta
     7861 gctcaataaa cggcaaaata tgaggagcaa tttttccgtt tattgagcta atactcagga
     7921 caggacgctg atttcacaac ctctagataa acggtgttca aaagccagtt tctcggtatt
     7981 aagccaaatt tatgaaaaaa tgtggaaagc cattttcaca aaatttttct tactactcga
     8041 aactaagcag ctttttcaca acctcttatt ctgaaaaata atttcctggc acaaccgtaa
     8101 tatttttcgt ttgagtatct acatctttga cataaagcag tgacgtataa tcatcgatgg
     8161 cgcgatgacc gttgaatttt gattcggcaa atacagtgat gccaacaagt tctgattcga
     8221 attcttcaat caagctcttc attccgttga ctgttccgcc gcctttcatg aaatcatcca
     8281 ctacaaggac acgtgaacca cgtttcaaac ttctcttaga cagttccatc ttttcaattc
     8341 tttcagaaga tccagacaca tagttgacac ttactgttga tccttctgtt atttttgagt
     8401 cccggcgtac aataacgaat ggcgcattca gataatagga cacagcttgg gcaataggta
     8461 cgccttttgt ggctacagtc attacagcat cgattttttc accaaggtat ttagaagcaa
     8521 tgattcttcc aacttgacgc agcagttcag gttctcctaa caaatcagag agataaacat
     8581 atcctcctgg aagcagacgg tcttgttctg atagacgttc tgctagagat tcaatatatt
     8641 ttttcgcctc ttcatatgaa atttcaggga tgaacaatac accacctgca gcacccggga
     8701 ttgtttccaa ggttccatac cctcgttctt taaatgtttt cttgatgatt cccaaatctt
     8761 cactgataga agatttagca gattcataac gttcggcaaa gcttgttaag gaaatcaatt
     8821 catgcgggtg attcaataaa tactgtgtca tgtcaactag acgttcactg cgacgtactt
     8881 tcacctattc caactccttt taagaaattt tatcgtttta cattatataa gtttttcttc
     8941 aaaaattcga gcattttatg aaaaaataag aaaatagttc ggtatttatt aaaataaaaa
     9001 gaagcctata aaaaattttt cgtttttata aggcttcttt tctttataat ttagttattt
     9061 tttcttctga aggcaaccaa tattcgtttg atgatattta caatcaggaa caaagcaata
     9121 aagactaatg tgattgttgc tcctggaggt gtatctagat aaaacgagct agttagtcct
     9181 gacagcatcc ctagaaatcc tacacaaaca ctgatagcaa tcacgacatt gaagcttttg
     9241 cctaatcgca taccgattgc tgcgggaaga accatgattg cggatatcaa aagtgcaccg
     9301 gcaatcggga tcatcacagc aatagccaca ccagtaatca cattgaacat catcgacatc
     9361 aaatgaacgg gtagcccatc cacgtgggcg gtatcttcat caaaagtcag aacatacatc
     9421 ggccgtttga ataaaaagaa caatataccg atggcaacga ataagattcc taaaaagatg
     9481 acttgctccc atgtaatggt cacgatcgaa ccaaacagat aggattggat acttgttgct
     9541 gaattccctc cgctcaaatt catcaatact aacgctagcg ccaaaccacc agccattaaa
     9601 atggcaatgg agatttctga ataggttcgg tagatcgttc gcagatactc caatatcaca
     9661 gctgctaata caacgactag catggtcgta agtgtaggat taaggttcaa aaagaatcct
     9721 aacgctaccc ctgctaaaga gacatgagaa agcgtatcag ccatcagcga ttgtcttctg
     9781 atcactaaaa acacacctag catcggggcg attccggcaa tgaagatagc ggcaagaaac
     9841 gctcttctca tgaattcata tgaaagcaac gccattgaga atcctccttt ctcaccagtc
     9901 ggatctgtct gtccgcatac tgtttgatat cttcatgatc atgggtgatc attagaactg
     9961 atttcccatg gacatgcgca ctatgtcgga gaagacgata aaattcattt ctggattctt
    10021 catccatacc tgttgttggt tcatcaagaa caaataagtc agggtcagta gcaaaaatac
    10081 gcgctaaact gattcgctgc ttttgtccgc cagacaattc acctattcgc cgatttcgca
    10141 tatcccacat ccctacagct tctaaagcac gctgtacatg ttgatgatct ttttcagaga
    10201 gacgcttgaa ccagcggcct cttggatatc ttcctgaacg gactaattcg atcaccgtac
    10261 taggaaaacc tgcattgaaa gatgcaactt gttgaggaat ataaccgata cttaattttt
    10321 ttccttcttg atttttctca gcaatcttta tcattccttt tgaaggtttc agtaatccta
    10381 acgatgcttt caccaaggtt gacttggctg ctccattttc tccagttaaa atgacaaatt
    10441 cacccgcatc tacatgataa gagacatctt ctagtacagg ttcatcatca tagtaaaagg
    10501 tcaaatcaga tatttcgata taacgcacct tacaacctcc attctaaaac ttaattgata
    10561 ctttctttta aagctttcag atttttttcc atgacagaaa tataattttc gcctgctttg
    10621 atttgttcat tagtcaagct ttctaaagga ttcaacactt ctagcttcac tcctgtttca
    10681 ttcgacaatg tctcagctac cttcgaagag gcattttctt caaaataaat cactttgatg
    10741 ttgtttttct tcacaaattc ttttagctca gctaagcgac ttggtgtggg ttcctgatct
    10801 ggtgaaacgc ccgaaatcgc tacttgtttt aagtcgtatt gattcgctaa ataagcaaaa
    10861 gcagcatgct gagtgacaaa tgtgcggttt gttgcatctt ttagctcatc ggagtatttt
    10921 tgatccagtg cttcaagctt tttgatataa gcatcggcat tcttcgtaaa agtttccttt
    10981 ttatctggat atttttcgcc taattcttca gcaatcgttc tgacttcttt tatagctaat
    11041 accggatcga gccaaacatg tggatcgtat tcatgtgaat gaccatgccc ttcttctgat
    11101 tcttcatgtt cgtctgcttc ttgcgattct aaacggtcga ttcctttagc tgcttcgatc
    11161 atcaaggtct gtttgctatc cactgaatcc tttaacgaat ccacaaaaaa ttccatgtct
    11221 gaactattat acacgaaaac atctgcatcg gaaatttctg ctctttcttt tgcacttggt
    11281 tcgaaatcat gcggctccgt tccagcaggg atcaaaagtt tcacgtttcc ttcatcccct
    11341 acgatctctt ttgtaaaatc atacatcgga taaaaagtcg taacgatcgt caaatcctct
    11401 tttttgtctg cttccttgtt cgtatttcca catgctgcaa acagtaaagc acctatcatt
    11461 accgtagctg tcaaaagata ttttttcatt tatatgctcc tttcaatgaa caaatcggaa
    11521 ttttacgatt tattaacgtg aactaatgta tcaaaataaa aaaacacagt caatagaaat
    11581 ccatcaattt ctgatttaag catgtatatt cttgattaaa tcgtaaaatg gatgagttgc
    11641 tgctcatatc tagccatttc actacaataa aaaactgaag aataccattt taggattcct
    11701 cagtttttca tcacctattt tacttcttat attttattgc agggttcgta ctaaataaac
    11761 ttcctcacaa aaacctttta acccattata tactctctgc gctcttgaat aatgttgaca
    11821 caaggcaaaa acggttggtc cgcttccact catcaatgca gcatctgctc cgtacttgat
    11881 catacgctct ttgatttgat ggatgactgg atgccgcttt cccgttatat cttctaaact
    11941 gtttcccatt tttttgatca tctgctgata atcttgctct cggatggctt cagcaagtcc
    12001 gtggatgtct tgatgttgga tggcttgcgt atctacttct ctaaacactg tacgtgtaga
    12061 gacactcatt cttggtttga ccaacacaac ccagcactgt ggcatagaag gtaatacttg
    12121 gatttcttcc cctttgccac cgacaaatgc cgtacttccg tagacacagt aaggaacatc
    12181 tgtaccgact tccaaaccga tttctgccag ttcttctaac gaacagccca gattccataa
    12241 ttggttgatc cctcttagag cagctgcaca gtctgtactt cctccgccta atccagctgc
    12301 tactggaata ttcttcttaa caaagatctt gacaccggtt ttgatattgt atttattttt
    12361 tagcaataaa gcagcttgat aaacattgtt ccgttcatct accggtaaaa atgctttatt
    12421 tgtttctaca atgattttgt cttctgttat ttcttcaaaa aatagatgat ctgccaagtc
    12481 tacgctcgac atcaccattt ccaactcatg atacccatct tgccgtctat ataatacatc
    12541 cagtcctaaa tttatcttgg ctggcgcttt ttcaatcaat tccatcctct cacccattcg
    12601 aaaagtctaa gtcgcaagta ttctatcata gggaaaaata aaagtatagc ttatgtctgc
    12661 ctagtggttg attttgtcat cgtttcaaca gctttcacag aattttctct tcataatcca
    12721 aacaagttct agtgattctt ataattctgt gagcacttct tctgccaaac tcggaacatt
    12781 tcctttttct tttcctatca gactgagtag ctgcatggta gcaaatccga aattacttcc
    12841 tttcctataa gcaaaataac gtccttccca atgatcgaca tattttaatt tcttttcata
    12901 agcagactgg aaggaataga aaaaattacc ataattatat acgatatgca tgactttttc
    12961 ttgaaagaaa gaaaaatctg tttctccaac attagctaat ggagctaagc ctagattggc
    13021 ttccgagtag cccattttct cgtatacaat aaacagattg gctaacagat agtcagctaa
    13081 ttcctcagat tctttaggta agacccgcaa caaatcatat cccgcctgct tcttcgtcat
    13141 cggctgagcg gtgatgaagc caacgacttt ttgatcttta cggacaatac cgacaccgct
    13201 agataataca tatgatttat caaatcgtcc cacagagaag tatttttctc gtgcaccttg
    13261 aagccatttt tgtgaaactt catttacagc ttgatgtaat tcttccggca gttgatcgta
    13321 ccaagtaaaa tggtatcctt ctttcatcaa acgttgatat tcaagttgct gactcagccg
    13381 agacaagtct tctgttgcta gatcaacaat ccctgcttca cctactttcg tgaagtgaaa
    13441 acccaattca tgaagcatca ctacgtagct ttctgatatc ttataaaacg caagctgata
    13501 gcctaaacaa tctgcttgtt tcataaactg attcgttgct gcccgcatca ttttaggatt
    13561 gccaactgga tctcctaaaa caaagcattt gtttcctttg atctgataac caaaaacgac
    13621 ttgatcttgg tcgtcttctt ggtaataaaa ataactgtaa cctgacaagc gaagctgatg
    13681 gcttgtagct gtgcctccgt atgtttccaa taaacggtca aaacggtctt tttcgtactc
    13741 actgccaagc ttcgtagtat cttcagctaa atattgataa agcgccacta aagctagcaa
    13801 tgagatgccc aaaccaataa gccctgagaa ccacacatca tctgaaggaa acaaaataaa
    13861 atgatttcct gttattcgac cgactaaaaa gcgtccgctg tgatagcctg caattgcgta
    13921 aacgataaac aaaaagccga acaagctagc atcaaagatt atagctcccc aagaataaac
    13981 gaattttgtt cgataaaatt cttttctgga taaccacaca gctaacagaa tcaagacata
    14041 taccaatatc aactgccaag ataacgtacg tgtgattgta tttaaaatac caaaagatag
    14101 taaagcaatc gtaggcagaa atgccttttt gacttttact gaaagtgctc tagcaaggcc
    14161 gagtaataaa aagccaacca atagattcac tgtctgatct aaaaaattga atgagaacgg
    14221 caataatact tgaaatagcc gactgattgc agacagatta gtgattgttg atagaagtac
    14281 catcatgatc cccgcaaaat agacagcact tacgagcacg atatgcgcaa ccttttggaa
    14341 aaacagtcgc ggaatgttat ctaaaaatcg attgattttg actcctgtat gtgtgatgaa
    14401 caatagaagt cccgtcataa aaggtagaac ataataaaac aaccgataat ataatagcca
    14461 aactactgct acatcttgcc gaacaggcaa ttgactcatt cctaagatca tcaaaacgtc
    14521 aaaagtcccc attccacctg ggaccatcgt cagcattcct atcaatgtag caatcatgaa
    14581 cataggatag atcgaaagca tcgaaatatc tattctcatc aacttgccga tgatcaaaaa
    14641 taccgcaagg gctcccgtcc attgtccaaa ggatgccagt agcagaccaa gcaagccttt
    14701 tggataaaac tcgaagaaca atgtctttct ctttagataa gcaaaaaaga aaatgactgg
    14761 tgctaaaaaa ctaccgccga aaagccagat ccaatagctt cgaaaaatac tttctgactg
    14821 aataaaaaag acatcaataa atgtaagaaa cgaccataca gacaaaccag tcagcataaa
    14881 tagtgcgact tttgatacag tggctaaaac catttttcta tttgtctgct ttccataaaa
    14941 actagcccgc agacttgctc ctaccacacc accaaaaccg gcgagattgt tgatcgtgtt
    15001 tgttacccac gcagcaagaa gaaactcttt tctttccatt tttggttttc cttgtttttc
    15061 taagactctg atcgtcaccc aatcatacaa caacatcgga gtgacaccca gcagtccagc
    15121 cagaatcatg agcaggatcg tcatgcggct ttgttgtccc atcctttgcc aaatatcttg
    15181 ccaactcatg ccattagcaa tatttgcgac ttgatttgcc acaaagacta acacggagcc
    15241 gaaaaaaatc agttttaaaa tcagactatg ttcctttatc cattgcagca tcaagtatcg
    15301 tttatttttc acattttccc attcctaact tgtatacttt tgtgtcatac cccaatgtta
    15361 tcttatttat tttaattttt ccactttaga cctgttcttt gcttgcgatg atagaaaaag
    15421 aaagatatcc taatgctaaa ggagaggata acatgaaagt aggatttatc ggcacaggga
    15481 atatggcaca agctattatt gatggtttat taaaaaaagg aacagtctcg aaagaagagg
    15541 tgttcgtttc cagtggacat tttgaaaatg cacaaaaatt tgctgctgaa actggcgtcc
    15601 atgcatgcaa aagtaatcag gaagttgcat cacaatcaga tatcgttctt ttagccgtga
    15661 aaccaaaaat cattgaaaaa gtattggaag aactaagaga atatagccag aaagtcttat
    15721 tcatttctat tgcttcagga aaatcattaa cagatttaga aacagcgctt gaagatcctc
    15781 aggcctccat cgtacgtgtg atgccgaatg tcaatgtcag cgtaggagca ggcgtttctg
    15841 cgatttgcaa aaatgaagct gccacggagg aacagcttca gcaagctacg atgatttttg
    15901 aagcaatcgg cagcgtctat cctttagcag aatcagattt cagtacattc attggccttg
    15961 ctggcagctc acccgcattc gtttacatgc tgatcgatgc gatgggacgg actggtgtac
    16021 tgaatggttt gtccaaacag acagccactg agattgctgc aaaagcaatt atgggttctt
    16081 gtcaaaaatt cctttcaagt gataaaaatc catgggaact tgtagaccaa gtttcttctc
    16141 ctggcggtac aactgttgca ggtgtagttg ccttagaaga agcaggattc atcccagcaa
    16201 tcatcaaagg aatcaatacg acgatcgaga aagatcttga gatgttgaat aaaaaataat
    16261 gatagcaatg ttttttcgtg ccttacaaaa aaagaagagc tgtggctttt gccgcggctc
    16321 ttcttttgta ttttttatta tttagcataa tcagttgcac gagtttcccg aataacgatt
    16381 actttgatgt gtccaggata atccagttct tcttcgattc gtttacgaat atcacgtact
    16441 aaacgaacag cgtctaaatc cgagatttct tctggcttga ccattacccg aacttcgcgt
    16501 ccagcttgaa ctgcgtaact tgattctaca ccggcgaagc tgttcgaaat attttccaga
    16561 cttcttaaac gacggatgta gttttctaat gattcacttc gcgcaccagg tcttgctgct
    16621 gagagcgcat ctgctgcagc tacaaggaca gagataacag aagtagcttc cacatctcca
    16681 tgatgagaag cgatcgcgtt gattactact gggttttctt tgtacttggc agctaattcc
    16741 gcaccgatct caacgtgaga tccttcaatc tcatggtcaa gtgctttccc aatatcatgg
    16801 agcaacccgg cacgttttgc taattggata tcttcgccaa gctctgctgc taagatacca
    16861 gctaattttg caacctcgac cgaatgcttc aagacgtttt gtccataact agttctgaat
    16921 cgcagacgtc cgatgatctt gattagatct ggatgaagtg tatgagcacc gacttcaaac
    16981 gctgcctctt ccccgtattc gcgaatacgt tcatccattt ctttacgaga tttctcgacc
    17041 atttcttcga tacgcgctgg atggattcgt ccatcttgta tcagtttttc caaggtcatc
    17101 cgtgcgattt ctcttcggat tggatcgaat ccggaaagaa caactgcttc cggtgtatca
    17161 tcgatgatta aatcgatacc agtcagcgtc tcaagcgttc gaatattacg accttctcgt
    17221 ccaatgatac gacctttcat ttcatcattc ggaagggtaa cgactgaaac agtcgtttct
    17281 gaaacttgat ctgctgcgca gcgttgaatc gctaatgata ataagttttt cgctttgcga
    17341 tctgcttctt ctttggcacg ctgttcagat tcttttacca ttagagttaa ctcatgattc
    17401 agctcttctt cagtcgattt catgatgaca tctcgtgcgt cctcttttga taaaccagca
    17461 attttttcta gttctttttg ttgatcttca atcatttttt caacgtcttt ttctcgctct
    17521 tcaattaatt gctgttttga actaagtgct tcttctttac tttcaagtga gttctcgcgt
    17581 ttttctaacg agtcatcttt acgattcagc gtttgttcgc gttgaatcaa acgattctct
    17641 tgagatttta attctaactt actttctctc agctcacttt caacttcaga acggtatttc
    17701 tgattttctt ccttagcttc taacaatgct tcttttttta gagtttctgc ttcttttttt
    17761 gcactatcga tgattccagc agctgatgat tgtgcaccag ctatttcttt ctcgtgacgt
    17821 gactttgcga ccataaaccc taaaccaaga ccgacaatta aaccgatgat agcgaggaga
    17881 atgttgaata ccataaaatc cacctccata ctatcttttt catttttatc atctatacag
    17941 cttctatgat aaattattct aaactcgtca atatgcatct tcgcatatat gtgtacaaaa
    18001 aacatgcaca actttattct aatgtttgta ccccgtagtg tcaactttaa ataaacaaag
    18061 aaacggcttt ctacttattc attaaacgat ggtttttaaa ataaatgaca ctagtttcat
    18121 ataggtaaac ctttaaattg agaaactttt ctattaaatt attctttgta gatgaacaga
    18181 tatttttatt ttatgtaccc actcgtataa ttaaataact cacgatttct ttattcaata
    18241 aaaaaacggc aggtcaagga gagtacctac tcttcagacc agccgttttt gtttatcata
    18301 atttttattc ttctactaaa ggcaattctt cttgtccttt ttcatcttct gggacagcga
    18361 cttcttcacc aataccataa gctgctctaa ctagagcaga aacttctgcc atcatttcag
    18421 gatgattagc catatagatt ttagcgtttt cccgtccttg accaatccga tcttctttat
    18481 aagaatacca agcaccgctt ttatcaacaa tgtctttttc tactgccatg tctagaagtt
    18541 ctccttcttg tgagatccct aaaccataca tgacatctac ttcagcgatt ttgaaaggag
    18601 gtgctacttt gttttttacg actttgatct ttgtacggtt accaacaata tctgtacctt
    18661 gtttcaattg ttctgcacga cgtacttcca aacggatcgt tgcgtagaat ttcaatgcgc
    18721 gtcctccagg agtgatttct ggattcccaa acatcacgcc tactttttca cggatttggt
    18781 tgatgaaaat agcgattgtt tttgttttgt tgatcgaacc agagagttta cgcaatgctt
    18841 gagacatcaa acgtgcttgt aacccgacat gtgagtcacc catttcgccg tcgatttctg
    18901 ctcgtggaac taaagcagca actgaatcga ctactacgat atctacagcc ccacttgata
    18961 ctaaagcatc agcgatctct agaccttgtt ctcctgtgtc aggctgtgaa agaagtagtt
    19021 catcgatatt cacacctaat ttttgtgcat attgcggatc taacgcatgc tcagcatcaa
    19081 tgaaagcggc cgttccgcca tttttttgta cttctgcaat agcgtgtagt gcaactgttg
    19141 ttttacctga actttcaggt ccatatactt cgatgatacg tccacggggg taaccgccga
    19201 cacctaaagc gacatctaac gcaagagagc cacttggaat tgtagagatt tgttggtcga
    19261 ttttttcgcc caatttcata atagagcctt taccatagct cttttcaatt tttttcagtg
    19321 cagcatctaa ggctgcttta cgatcatctg ccaatacgat aatcctcctt atatttacaa
    19381 atcagagcaa catttcatta tccttatcat atctttttta gtgaaaaaaa gcaagaaaaa
    19441 accgaacaaa tattcgcatt tatcattttc ttaaaagctg ttttctcaaa agatcaaatc
    19501 cttgcataac cgcattatat ctgatagcag cacgatctct ggcaaagtga tatttttccg
    19561 aaaccacgcc gtctttagat gaaatagcga tccatactgt tcctgcagat tgaccttcta
    19621 acgtgtccgg tccagccact ccggtgaaag ctacactgta atctgttctt gctatctcac
    19681 gtgcttgaat ggccatctgc tccacacatt ctttgctgac tgttccatat tctgctaata
    19741 gctccggatc aatctccaga aaaccagctt ttgtttggag cgagtaggta acgaatccgc
    19801 ctggaaatac ttcagataca ccagcaatgt cgcctaatgc ggcttggaag gcgccggctg
    19861 tcaaactttc cgctgctgtt acagtctgct tgttttcttt cagtagttcc actacgactt
    19921 ttgctagcga attatcatcg ccgtatccat aaaaatattc ccctactcgt tcttggattt
    19981 tttcttctaa tgctaaaaga gcttgattcc ctgcctgaac atcatttgtt ttcactgtca
    20041 gtcgtaatgt cacttcattt ggtttggcat atggtgcgat cgttggattg atctgtgtct
    20101 caatcagatc ttttagctca gtgaccagtc gcgattcacc aatcccataa aagcgcaaaa
    20161 ctttagaaat tagtttttct tcagaaggaa aacgttcctc tagtaaagga cgtacttgtt
    20221 ccacaaacat tggtttcaac tcattaggcg gaccgggaag aaggatatac gcatgtgtat
    20281 ctgtttgata aaaagtccct aaagcaagcc ctgtacgatt tggtagagga accccgcctt
    20341 cgataatctg ggactgttgc agattgtttt tggtcatttt tcgatgggtt gtttcaaaat
    20401 atgccaataa ttttttgtat ccttccgtat tttgtatgag agacttaccg aggtgagccg
    20461 cagttgcttc ttttgtcagg tcatcttctg tcggtcctaa tccgccacat aagagtatga
    20521 gttcacttct tgtttcagct agagcaatca actcttctaa acgctgctga ttatctccta
    20581 caactgtttg ataataaact tcgataccta gatcagctag ctgttctgac aagaaagtgg
    20641 cattcgtatt cacgacttgt cctagtaaaa gttctgttcc gacagctatt atttctgctt
    20701 tcattacttc ccgctccctt atatagtata cgctgtattt ttatattttt ttatttaaaa
    20761 agagggcaag gagctgtgac aaaaatcttg tcacagctcc ttgttccaaa taaacagtgt
    20821 tctcctgcca aaacctcggt cataagtcac aatatacata aaacatgaaa agctgttttt
    20881 tgaaattatc ccttgtgact cagagttaga cggcaggctc acaacctctc cactaaacga
    20941 tacttacatt gatcctttga acacaccgct gtttttgatg aagtaatcca cacctgaata
    21001 gatagtaaag atcagacaag cataaagcat gatttgatct actggaatac cgatcaggct
    21061 gaatgggata ttattgataa acagcaagat aatagcaacc atttgtgtag ccgtcttgac
    21121 ttttcccggc caagctgcag ccatgacttc tccatgttcg acaagtagta aacgcaagcc
    21181 tgtgacggct aattcacgac agacaatgat cgctactacc caaccagggg cctttccttg
    21241 gtcaaccaac atgataaaag cagtcataac tagcatttta tctgccaacg ggtccgcaaa
    21301 cttgccaaaa ttagtgacaa ggcctcgcgc acgggcaatt tttccatcta accagtctgt
    21361 gatactagct aaagcaaaaa taactgcacc tactagctgt gtgacagcca gtgtggtgtc
    21421 tcctacgtta aattgtcccc aatctaaagg taaacctaca accaaaatga aaatcgggat
    21481 catacaaatt ctaagtacag ttaatttatt tggtaaattc acactatcga ctcctttctt
    21541 ccctattcta cgtgactatc agcgaagttt ccaccgatat tatttacttt tccaaatgaa
    21601 tttattcaaa ggagtatttt tattgaaatt gatctttttg aattaacgaa gaaggaccgc
    21661 gacacagatt tgtcacgatc cttctttttt atacctacaa gtaaacagat gcgtaaacta
    21721 atttatacga tcattctgcg tattgaagag taaggttcac attttttgga ctctgattgt
    21781 tttcccctgg attaactggt acggattctc cattcgcttt gatcgttgca ttgcttgctg
    21841 caccaatcgt gatggtcgca tttgttgctg tttccggtaa cacggtactc tgtgtttcat
    21901 ttgctgccag tgtcccttga taaacatagg cattgtctac tagcacacct aaccatacac
    21961 gattgacagc agtaaattca agggttacag gcttggtagc gtctgtgata tttactgcga
    22021 tggcactgcc agaatcttct cctgtagcta ttgccatttt cttttcttca cttgattttg
    22081 ttgttgattc tactgtagaa gactctttgg tctgcgtgct ttgctctgag gaagaggact
    22141 cctcgactga tccttctact ttaagcgaag aagctgtgtc tccgattatt ggatcagctt
    22201 gacgatcttg ccaagtcata tagcccacga caacgacaat cgccaaagca accaatccta
    22261 ataaaatgac aggaagactt gtccaaaagc gacttggatg cgattcttcc tgatgcattg
    22321 cttttctaga agtacttact gtttcaggct gcggacgttc agggaccgat cctgtcaatt
    22381 tgcttttccc atcaaaaaca tcgactaaat ggtctccatc ttctcctaca gcttcagcgt
    22441 attgccgaat aaatgcccgc acgtaaaatt taccaggcaa ttggtcaaaa tcatcattgt
    22501 cgattgcttc caaataacgt ttttgaattt ttgtaatctg ctgtaattca tctaaagata
    22561 tttttttatt caggcgtgct tgccgtaatt tttctccgat ggtttcaaaa gccactcgtt
    22621 catcttctcc agtctgtttg attctccgaa gcatctgctg ttgcaacgaa agacgttatg
    22681 tttgggtgct gtgacaaaag tcatgtcaca gctccttttt tccgaataaa cattgttctc
    22741 ctgccaactc ctcggtcaca agtcacaata tccaataaat ataagaagct gttttttgaa
    22801 cttgttcctt gtgactcgga gttaaacggc aggctcacga cctctttctt aaacggtgtt
    22861 caatcagctg ttcctcggta ttagctcaaa aaccggcaaa atataaggag atatttttcc
    22921 gtatgtttct ctaatactca ggtcaaaacg ctgatttcac aacctcttcc ttaaacggtg
    22981 ttcaaaagct tgcatctgcg gtaataagtc caaccaagtt aaaaacatta agaagctgtt
    23041 tttacttggc tgttcttatt acttgatgca gggcagcttt ttcacaacct cttggtacac
    23101 ggtgttccag aagtagcttc ttcggcaata agccgaaata tcacaaaaat ttgagaagca
    23161 attttcgtaa attccttctt atttcttgaa gctgaccact tctgtcacaa cctctttgat
    23221 tacttcgttt gattttattt taatataagt tgattaaaag agagcatgat ttgttttatt
    23281 ttctcactaa tttttccaac acaactaaga ataccataaa agctgatttt ggaggaggtt
    23341 cctactacaa gtctaaaacg aaatttaaga cttttcctca taaatactgg tttattttgg
    23401 tctcatgtaa aactcgctga aggcctcttc acttataaat gcttccccag ctgccagtac
    23461 gtctttcatt tggatcgaat cgatgatttc aggaagatca aataaagttc gatcgccaaa
    23521 taaactttgc gtaaattgat tggcaatata ttcgatcgaa tttaatgatt ggaaatattg
    23581 tccaagcatt ttcttcttca gcaaatcgag atttgtttct gacacttccg gatcatcagc
    23641 gaatccaaga atgatttctt tgactttttc tgctgctttc tctggttcgt ccgtatctcc
    23701 gctgaagtcc gcaaagtgaa attcacgatc caagctgaat tcaaaaccaa agctgtcatc
    23761 gataattcct tgattgtaca tcgctagata gtttcgagaa gtattgccta aaatcatttg
    23821 gaacaacaga ttgattgctg ttttatagcg taacagttct gttccttctt gcggcaatgt
    23881 gtctaatcct ttaataccaa gtacaaattt atctcgtgta atggctgctt ccaatgcact
    23941 ttgtttgatg atttcttttg tgttttcagg gaaataacgt acaatttctt gctttggagg
    24001 gaaatttttt gcttcttggt tttcccgaat aagtttcatc aatttctcag gctccatctt
    24061 accaactaca aataaaacca tattgcttgg ctgataaaac gtccgatagc acgtatacaa
    24121 gtcttgagct gtgattttgt cgatactttc aaccgtgccc gcaatatcga tatgcaatgg
    24181 gtgtgtagga tacaagttat ttagtatgcc aaaaaacatc cgccagttag ggtcgtcttc
    24241 atacatttgg atttcctgac cgatgattcc tttttccttg tttacagttt cttctgtgaa
    24301 gtaaggtgct tgtacaaaat cgatcagagt cgtcagattc ttttctacct gatccgtcgt
    24361 agaaaacaga tagctggttt tcgtaaaact tgtgaaagca ttggcggaag ctccttgttt
    24421 cccaaataat tgaaagacat caccatcttc tttttcaaac aacttatgtt ctaaaaaatg
    24481 ggcaattcca tctggaactt tcaccttttc tttttcacca tagggaataa attcgttatc
    24541 gatcgaacca taattcgtac tgaacaaacc atatgtcttg tgatagtcat ttttaggcaa
    24601 caaatacacg gtcaaaccgt ttggcagtac ttcatgataa agtgtttcat tgatttgctc
    24661 atattctgtt ttattcattt gcatttcctc ctgctaaaaa gaagattgcc tgcaattcga
    24721 tttgctcagc tacttgttgt atctctttga tcgttacgct ctccatacgt ttcaaccatt
    24781 cttcatcaga taattttgtt tccggcagcc agctgtccaa aaaagaagct tcgattgccg
    24841 cttgcggaga gtctagagaa agcagatatt ggtttctcag cattgctttt gtctgagaca
    24901 gttccaactc tgttatttca ccatttcgca aactttctaa ttgctcgtga atcagatgaa
    24961 gtacttgatt tcggttcttt tcatcgatac cggtttggac actcatgaat cctcggaacg
    25021 tatccacgct actagaggca taataagcta gactttcttt ctctctgaca ttcatgaaaa
    25081 gtttagagtg aggaaaaccg ccaaataaac cgttaaagac cattagcgca aaacgttctg
    25141 gttcatcgta atacacattt gtctgataag ctaggttcag ctttgcttga acgattggct
    25201 cacgtacttg tcgttccttc acgatattca cttgaggttg ggtataaaac agatctggat
    25261 aaactgtttc ccgcgactca aatggtaatt gcccaactgc ttcagctgct ttgtccggat
    25321 caacatcgcc gacaacaaaa atgtcgattt gatcatttgc catcatttct tgatagtagg
    25381 acgctagcga actagcagtg atcttgtcca aatcttcgac tacgcccaac cctgggatct
    25441 tttgttccgg gctgttttca aaataaagtt cttgcaaggc ataggaagca aaagtttgtt
    25501 tatcttcctt caaactttcc aaatatagac gcagattgtt cttttccaag tcaaacgtca
    25561 actgatcaaa ctgatgattt ttaatatttg gataaaataa aacctctttt aaaaaatcta
    25621 ccgcttgaga aaaaaggttt ggatcattga catattcacc attcacaaaa ctgatccctg
    25681 cgtttagcca atgtaaattt cctttttttc taactgataa tccaaagctt gcgccataaa
    25741 gctctgcaag ttgcgcactt aactttgtct gatccggata attcaaacta tttgtttcca
    25801 acatgctgct gagaagtgaa cgtttcgtga tgacttcttg ttgcagacgc gcagtaaaac
    25861 ggataaaaat ccggatcgtt ttgtattgtt ttgttggtaa gacatgaaga ttcacgcctt
    25921 ctgccaattg atacaccata tttatatgct ccttttcaca gttgattgcc cgcttactct
    25981 tttaatgggt caacctgcct tttttactta ttcctctgct tgaaatttat aagttcaggc
    26041 aattcgccgt tttttctaaa tgatgttaca ctttatagta tagcatagat gttttttatc
    26101 aaaagaaaca gacggctaaa agcgtatatt gtttttttat tttttatttt tcgatatact
    26161 aaagacaaat aaaagaaggg agggtcattc atgatcaaag aattcaaaga gttcatcatg
    26221 cgtggagatg tcttggatct tgctgtcggc gttgttattg gtagtgcgtt tacaagcatc
    26281 gtaaaccaag tggtgcaagg cttgatcaca ccactaatag gttggtttgt cgcaatgatc
    26341 acaggtactt ctgatttaga aggagcactt tcaattcttg actggtcgcc gacaaaaggc
    26401 gtcacatttg cgtttggtaa cgttattagt gctatcatta catttctgat cactggtttt
    26461 gtcttattct tagttgtcaa agcggcaaac cgtgcgaaga atttacgctc caaagaagag
    26521 caagtggaag tggaagaaac tcctactgca gaagattatc ttagtgacat acgcgatctt
    26581 cttgccaaac aagtggcaga agacaataca catccagtag agcaaacaaa tctttccgat
    26641 acttctaaat aataaagaat ctaaaaaaaa gaaagccgat tttcagtgtc ggctttcttt
    26701 ttttagattc ttaacttgct acttgttcct ttttcatgtc gatatgtgga atatcatctt
    26761 ccaaatacac atctgagatt gccttgaatc caaacgactc ataaaaagct tgtaggtatt
    26821 cttgtgcgcc gatcacgatt ggtttttctg gaaaattttt ctggatcatg ttaatcgttt
    26881 cttgaacaat ctttcttcct aaaccatctt tacggttgtc ctgatgaaca aggacacgtc
    26941 caaaatggat actctccgct tcttcatata ctcgcgtgta ggcaaggatc ttcccatcag
    27001 tatcttgaaa aaacgtatgc caagcttgtc catcaatgtc atcaacttct tgataaggac
    27061 actgttgttc cacaacaaaa actgcgattc gttctttgac gatcgcgtaa aactctgctg
    27121 ttgacaattc ttcaaatttc tttacctgat attccactaa gcaaacgccc cctgcttttt
    27181 tattcttagc ataccgattc gcacacaaaa aagcaaacga accttacgaa tc
//
LOCUS       DACGEU010000034        26994 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.034, whole genome shotgun sequence.
ACCESSION   DACGEU010000034 DACGEU010000000
VERSION     DACGEU010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26994)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26994)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26994
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.034"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(151..2304)
                     /locus_tag="IXR40_001334"
     CDS             complement(151..2304)
                     /locus_tag="IXR40_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HAQ4361192.1"
                     /translation="MMKDFMKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFF
                     IIFTLFVALIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKA
                     NQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKR
                     LSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGV
                     TDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLA
                     KGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSM
                     NAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEI
                     TENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRS
                     GQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFG
                     LGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYTPIQLAQ
                     YASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGF
                     HQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEI
                     AISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
     gene            complement(2598..3446)
                     /locus_tag="IXR40_001335"
     CDS             complement(2598..3446)
                     /locus_tag="IXR40_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAQ4361193.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDSK"
     gene            complement(3670..5610)
                     /gene="thrS"
                     /locus_tag="IXR40_001336"
     CDS             complement(3670..5610)
                     /gene="thrS"
                     /locus_tag="IXR40_001336"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HAQ4361194.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(5947..6126)
                     /locus_tag="IXR40_001337"
     CDS             complement(5947..6126)
                     /locus_tag="IXR40_001337"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HAQ4361195.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(6173..7996)
                     /gene="cadA"
                     /locus_tag="IXR40_001338"
     CDS             complement(6173..7996)
                     /gene="cadA"
                     /locus_tag="IXR40_001338"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HAQ4361196.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            8274..10553
                     /locus_tag="IXR40_001339"
     CDS             8274..10553
                     /locus_tag="IXR40_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAQ4361197.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(10646..11293)
                     /locus_tag="IXR40_001340"
     CDS             complement(10646..11293)
                     /locus_tag="IXR40_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361198.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(11472..12191)
                     /locus_tag="IXR40_001341"
     CDS             complement(11472..12191)
                     /locus_tag="IXR40_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAQ4361199.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(12322..13473)
                     /locus_tag="IXR40_001342"
     CDS             complement(12322..13473)
                     /locus_tag="IXR40_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HAQ4361200.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(13690..14430)
                     /locus_tag="IXR40_001343"
     CDS             complement(13690..14430)
                     /locus_tag="IXR40_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAQ4361201.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(14434..14757)
                     /gene="rsfS"
                     /locus_tag="IXR40_001344"
     CDS             complement(14434..14757)
                     /gene="rsfS"
                     /locus_tag="IXR40_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HAQ4361202.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(14814..15407)
                     /locus_tag="IXR40_001345"
     CDS             complement(14814..15407)
                     /locus_tag="IXR40_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAQ4361203.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(15391..16038)
                     /locus_tag="IXR40_001346"
     CDS             complement(15391..16038)
                     /locus_tag="IXR40_001346"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HAQ4361204.1"
                     /translation="MNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHLV
                     MAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIELA
                     RGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPGY
                     TTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(16051..16362)
                     /gene="yhbY"
                     /locus_tag="IXR40_001347"
     CDS             complement(16051..16362)
                     /gene="yhbY"
                     /locus_tag="IXR40_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HAQ4361205.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(16378..17487)
                     /gene="yqeH"
                     /locus_tag="IXR40_001348"
     CDS             complement(16378..17487)
                     /gene="yqeH"
                     /locus_tag="IXR40_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HAQ4361206.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNETQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(17484..18011)
                     /locus_tag="IXR40_001349"
     CDS             complement(17484..18011)
                     /locus_tag="IXR40_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HAQ4361207.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(18191..18976)
                     /locus_tag="IXR40_001350"
     CDS             complement(18191..18976)
                     /locus_tag="IXR40_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HAQ4361208.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(18969..19838)
                     /locus_tag="IXR40_001351"
     CDS             complement(18969..19838)
                     /locus_tag="IXR40_001351"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HAQ4361209.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(19839..21218)
                     /locus_tag="IXR40_001352"
     CDS             complement(19839..21218)
                     /locus_tag="IXR40_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HAQ4361210.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(21226..21645)
                     /gene="fabZ"
                     /locus_tag="IXR40_001353"
     CDS             complement(21226..21645)
                     /gene="fabZ"
                     /locus_tag="IXR40_001353"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HAQ4361211.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(21670..22146)
                     /gene="accB"
                     /locus_tag="IXR40_001354"
     CDS             complement(21670..22146)
                     /gene="accB"
                     /locus_tag="IXR40_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HAQ4361212.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVIPEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(22149..23384)
                     /gene="fabF"
                     /locus_tag="IXR40_001355"
     CDS             complement(22149..23384)
                     /gene="fabF"
                     /locus_tag="IXR40_001355"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HAQ4361213.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(23403..24140)
                     /gene="fabG"
                     /locus_tag="IXR40_001356"
     CDS             complement(23403..24140)
                     /gene="fabG"
                     /locus_tag="IXR40_001356"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HAQ4361214.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(24152..25069)
                     /gene="fabD"
                     /locus_tag="IXR40_001357"
     CDS             complement(24152..25069)
                     /gene="fabD"
                     /locus_tag="IXR40_001357"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HAQ4361215.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEAAPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(25176..25400)
                     /locus_tag="IXR40_001358"
     CDS             complement(25176..25400)
                     /locus_tag="IXR40_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HAQ4361216.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(25453..26415)
                     /locus_tag="IXR40_001359"
     CDS             complement(25453..26415)
                     /locus_tag="IXR40_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HAQ4361217.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(26425..26865)
                     /locus_tag="IXR40_001360"
     CDS             complement(26425..26865)
                     /locus_tag="IXR40_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAQ4361218.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
BASE COUNT         7368 a         5990 c         4691 g         8945 t
ORIGIN      
        1 aatttttgtc acaacctttt ttgccgagta aacggtgttc aaaagccagt ttctcggtat
       61 gaagtcaaat ttaagcaaaa atgtgagaag ctattttcac aaaatttttc ttcatactcg
      121 aaactaagcg gctttttcac gacctctttt ttattttgcc atgaacatat cataatacgc
      181 gtccattatt tctttagcaa tcgtcaagtt tatgtggtct tgttcgtcta ataagttcgg
      241 caagacaaca ctgatggcaa tttccggatt gtctgttggt ccgtatgcca cgatattact
      301 attgactgtc gcaatatctg gatgaccttc cgcaaccgtt tctgcagtcc ctgtttttgc
      361 ggaaaggtcc attttcgcac tggctaatgg tttggctgtt gtgtaaggat cggtaccatg
      421 gacaacttgg tggaatcctt cacggaggat cgccatattt tctgcagaaa tattgaccgt
      481 attttctact gttgtgccaa tttctttctt cacttcaccc aagtttccat tttcgtcatt
      541 gccatagatc gctttgacta ggtgcggctg tactcgtttc ccgccattag cgactgttga
      601 agcatattga gctaattgga ttggtgtata tgtgtcaaac tgtccaaatg ccaaatcggt
      661 aaagttacct ggagcatacc attctttgcc attatccgca ttgaacttct tcatataatc
      721 aacagaacgt gagatcccag gagattcatt cggcaaatcg atcccagtcg ttgtaccaag
      781 accaaactct ttgaaagagt ctctcaattg ctgataagct ttagcttctt catctaaact
      841 aggtagtccc attccaggtg tatagtctag tcctaacatc tttaacgcca ctttgatcat
      901 atacgtatta gaagacaatt ccgatgcttt gactgcatca agagcaactt gtccgcttcg
      961 attaaagaca gagctttttt ctgaagcacc ttgcagacga atcggctcat caatcaaaac
     1021 ttgatttccg ctgatcgcgt tacttgccca gcctgctgtc aaagtaccag ccttgactac
     1081 agaccctgga tcaaaggcgc tagtaatcgt gcctaaagca ttctcggtga tttctttgga
     1141 accttgttca tgactgaaac cagtcattgc tagcacttct cctgtctgag gattcatagc
     1201 cactgcataa gcaccaggcg aatactgtgc tttgccgttg ttgatcaatg tttgataatt
     1261 ccttttcaaa atttcttcta cttttgattg gaattctgca ttcatagata acattaaatt
     1321 agaacctttt tccccagaga agatttcttt ttgattcgaa acatttcctt cattatcaag
     1381 ggaaacttca tattgggttt tggttccttg caggacatct tcatattgtt tttccaaata
     1441 actttgtcct acacggtcat tccgagaata accttttgct aggtatttct ctgcttcatc
     1501 tgctggaagt ccttgctttt cagtcgtcac actgccaaga atacttttca gtgaacttgc
     1561 tgcattatat tctcgtgtcc agtctgtgcc agtcgaaact cctggaagtt cagaagcgcg
     1621 ttctgccaca acagctaact cttgatcagt aacaccagag tttttgatat agacagtgtt
     1681 taattcatat gcactattca tccgtttaaa gatggtagca atttttaatt gctcctcgtt
     1741 taaattaatc tcatcagctg tgactttatt gaccatcgca ctatattgtt cgctgttccc
     1801 taattgcttt tcttttgccg aaagtctttt tgtggcttct ttcaaatgtt tgggatcagc
     1861 cagccaaaaa tcttttttat ctctatctgt cagattttca tctaccggaa catcgatcag
     1921 cgagttcagc ttcgttgcga tttcaagcaa atctttagcc gtaacttgtg ttcctctcgt
     1981 atatgtgatg gcctgattcg ctttattcgt aactaaagct tttcctgtgg agtcgtagat
     2041 cattccgcga ggagtacttt cttggaccgt aatcgtagaa gtagacttca ctcgcgcctc
     2101 catctcttcg ccgttcacga tctgcaaata acccaatcta gcaatcaacg caacaaataa
     2161 cgtaaatata atgaaaaaaa gaaaatttaa gcgaaaagga acatgggacc ggcgaaacgt
     2221 tttgttctta ggttcttgtg caccttttct tattttttct aaccaagaag tatttaatat
     2281 ttttttcata aaatctttca tcatttccta tccttccgcc tatttacatt catgcttcat
     2341 tgtacccaaa aacttcttaa taaaaaagaa aaaatgggcg gagcaagaaa ttctttacct
     2401 aatttcaaga taaaatcaac tttttgtttc acagcaatca cttaaagtta catatccaac
     2461 tatttttttc attaaaaaat aaacttattt ttgaaaatta tgttttctta agtcgtgaaa
     2521 cactttgatg gatcatttat ttgtggaaaa ctacgttttg ttattctaaa aaacttatat
     2581 aaaaaatagt aaggttttta tttcgaatcc ataaaatatt cttggattgc ttctcgtgtt
     2641 tttttcactt tttcgctaag cttttcgttt ttagccatat agaaataaaa aatgatatcg
     2701 atcgtagcaa attgggccaa aagtgaatta gttgccgcac ttcgattcgt gatttctttt
     2761 ggtctagatg tttgtacgag tacatcggct atcttgctaa gcgggttatt tccaaattgc
     2821 gtcaacgcaa tgatttcgat attcatgctt ttcgccagct cggctaatgc gactacatct
     2881 gcacttctac ctgagtttga aacaagccaa agcactttct ttttctcatt gctgacaagt
     2941 tgcgggagca agacgtggat atctttttca aaaatgattg gcttaccgac acgagaccat
     3001 ttttgcagaa tatcttctac tactaaagaa gaggcgccaa ccccatataa aaaaacagtc
     3061 tctgccgatt ccaaacactc tacgactttt tggatcgttt cttcttctag aatatctact
     3121 gtttctttta tcgctacttg tgcattgtta ccaagtttgt ttttgataga gtaaaaggac
     3181 tcatttgctt ctatatcact aaaaccttca tcgattccag tctgtagttc tgttgaaatc
     3241 gtgattttga agtccgtcag actttgaaaa ccgatttttt tggaaaaacg tacaactgtc
     3301 ggcgcactca acccggaagc ttctgctaat tcattagctg tcattgtagg gaccttctca
     3361 atattaccga taatgtagtt ggccaacttt ttttctgctg aagaataatc ttccatcata
     3421 ctttcaatac gactaattac gctcataagt tcctccaccc ttttaatgat agtctatgta
     3481 agtataccat atcagaccct tattcacggt cgtatactgg ataaaaaaca aaaaaacaat
     3541 ccgcccaaca gaatatctta tcccatcaat cccacagatt ctattgagca tctgtgtctt
     3601 tgaggaatac ctgttatcta ttgttcggat tgctttctat ctactacttt tttacaggaa
     3661 atttacctat tagttttctc tgctgtaatt tttgacttct gcttccatag catcaataaa
     3721 gatattcaaa tcttctacag ctgtttcttt acttccataa cgacgtacgt tcactgttgc
     3781 atcttccaat tccttgtctc caacaactaa ttggtaaggg atcttttgtg tttgagaggc
     3841 acgtatctta tagcccattt tttcattacg atcatcaact tctacacgca accccttcat
     3901 ttgcaaacgt tctttgattt cataagcata atcgccatgt gcatcaacag aaacagggat
     3961 gattgttgct tgtataggtg ccaaccatgt tggaaaagcg cctttgtata cttctgttaa
     4021 ataagcgaca aaacgttcca ttgtagaaac aattccgcgg tggataacta ctggacgatg
     4081 cgtattttcc ccgtcttctc caacatatgt caaatcaaag cgctctggca ataagaagtc
     4141 taattgtata gttgataatg tttcttctgt accaagagct gttttgactt gaacatctag
     4201 ttttggtccg taaaaggctg cctcgccttc tgcttcaaag taatctagtt ctaattcatc
     4261 catagcggct ttcagcattg cttgggcttt ttcccacatt gcgtcatcat caaaatattt
     4321 atctgtattg tttggatcgc gatagctcaa gcggaaacga taatctgtaa tattgaagtc
     4381 agcatatact gccaccatca attcaagcgt acgtttaaat tcatctttga tttgatcagg
     4441 acgaacaaat gtatgaccat cattcaacgt catttctcgt acacgttgta aacctgacaa
     4501 agcacctgat ttttcatagc gatgcatcat tcctaattca gcgatacgaa ttggtaattc
     4561 acgataagaa tggatcgtgt ttttgtagac catcatgtga tgagggcagt tcattgggcg
     4621 aagaacaagc atttcgccat ctcccatatc cattggcggg aacatgtctt cttgataatg
     4681 atcccagtgt ccagatgttt tgtacaactc aacatctccc attattggtg tatatacatg
     4741 ttggtaacct agactaactt ctttgtctac gatataacgt tcgatcgtgc gtcggattgt
     4801 tgcccctttt ggaagccaga atggcaaacc agaacctact tctggggaaa ccatgaacaa
     4861 gtcaagttct tttcctagtt tacgatggtc tctttctttt gcttcttcac ggagacggat
     4921 atattctttc aaagctttct tgtcaaaaaa ggctgtcccg tatacacgtt gcatcatttg
     4981 attgtttgag tttccacgcc aataagcacc tgccactgat aataatttaa atacttgtat
     5041 acggccagtg gatggaacat gtggtccacg acacaaatcg atgaattcgc cttgttgata
     5101 agcagtaatc acttcttctt ctggcaattc actaatcagt tctactttgt acggatcact
     5161 tgcaaaaatt tctaatgctt cctgttttga aagaacacgg cgttcgatcg gcagattttc
     5221 tttgacgatt ttcatcattt ctgcttcgat tgccggcaaa tcttctgcag ttacttggtt
     5281 ttgtccatta tctgtatcgt agtaaaaccc tgaatcgata gctggtccaa cgccaaagtg
     5341 gatatttgga tagaggcgac gcatggcttg ggccatcaaa tgagctgctg aatgacggac
     5401 taagccaagt gcatcttcat ggtctggtgt gatgatctca atacttgcat cttcctcgat
     5461 tggacgagtc aaatcaacga gttttccgtt cactttacca gctaaagctt tttttgctaa
     5521 gctttttgaa atgctttcag caattgccaa tgttgttgtt ccagactcaa attctttgac
     5581 tgcaccatct ggaaaagtaa tttttatcat aatagtttcc tccttgaaat gttttgattg
     5641 atcagatcat caagctgaaa aacaaaaaaa tcctagcatc tcttgaaaag agatactagg
     5701 acgaaaagtt cgtggttcca cctaatgttc aaacgcaaat gcgttcctca agcgttgtaa
     5761 cggtccgacc gcccttgctt caacaagggt ttcgaaagtg gtcatccttt ggttttctcc
     5821 tggaaaagtt tcagcctagc ttttcctctc ttatcgaaga ctctcaaatt cagttggctt
     5881 tctcatcaat caattatgtg tttatttaac cactaataaa tagaaaaatc aagtgggaaa
     5941 ctaaacttat tttttccatt ccccatttac accgtatgtt ccttttttca tctcattgat
     6001 gatgacatgg atgtgttctt ttggtgcctg cgtgttttta tgaacagctt ccgtgatatc
     6061 tttcatcata ttttctaatt gttccggact gcgaccttct actaattcga catgtacgaa
     6121 tggcataatg ctctctcctc tttctgatcg ttcttttttc aactcgattc tatcatacta
     6181 tgtttgtctt gggtactgaa tcaggaaaaa tggctggatc tttttttgct ctcaaggcac
     6241 tcaaaataga gaccgtatcc acgacttctt gcaaaacagc tccgaataat gcggggatta
     6301 gtcccgtact tgcaattaac atcaaaaaaa tacaaataaa gatgccaatc agtacagact
     6361 gtttcgctat tctcatcgta tctcttgaaa tcactactgc ttttgctaca cgcaagagat
     6421 catctttcaa gatgaccgca tctgcacttt cactagcagc tgtagaacca tgagccccca
     6481 ttgcaatacc gatatctgca gcagcaagtg ctggtgcgtc attcacgccg tctcctacca
     6541 tcgcaacagg tctttgatct ttagggatac tttctaaaat ggtcagttta tcttgaggca
     6601 agctacgggc atgtacagaa tctaattgga ctttttctgc aatcgtttga gcaatggcag
     6661 atccatcccc ggtgatcatc atcaaatttt tcacatcaag ttttcttagc tccttgattg
     6721 tctttgctgc ttctgggcga atctgatccg aaaataggat cgttcctgca aaagatcgat
     6781 caattgttac atagattgct gtattggacg tttctatttc ttcagctgaa acaaaagagg
     6841 cacgtccaat ctttacttca tgattattga ctactgcttg gattccttga ccggtcactt
     6901 ctttcagttg actaacagga tacagttggc tgtttttcac gttgttcact aacgaacgag
     6961 ctaagatatg gctagattcc tgttctgcac tagctgcata cagaagtagc tcttcttttt
     7021 ttattccatt gactggctga atcgcctcta cttccaatat ccctttggta agcgttcctg
     7081 ttttatcaaa agcaatcgtt tttgtacgtg cgagcttttc aatcgttgtt ccagttttta
     7141 caacgatccc gtttttactt gaacggctca ttcctgcaac taaagcaatg ggcgcagcta
     7201 gaatcagtgg acaaggtgat gccactacca gtacctcagc aaatcgtaaa gggtcttttg
     7261 agaaccacca agaaatacca ccgatcaaat aagcaatcaa cgtgaaaggg actgcataac
     7321 gatcagctaa acggacaaat cgggcaggct tttcttttga ttcttcgact agtttaataa
     7381 tcatttgata ctggctgtct gcggcacgtt tttcagcgat catttggatc gatccgtctc
     7441 catttaaaga ccctgacata atctgatctc caggtttctt ggtttccggg cgggactcac
     7501 ctgtcaaaga agattcatcg accgaagatt ctcctttggt cactcgacca tctgcgggta
     7561 caagttcgcc aggcttgact agtaactggt catcaatatt tatttcatcg attactatat
     7621 cctgcaattt tccttctttg aatcgatggg caattcttgg ggtgttatct aacaaagact
     7681 gcagttcttt acccgctcgt ttattcgcgt aatcctctag actatctccg cccgtaagca
     7741 tgatcaatat catcaaacta gcccagtatt ctttgacggc taatgttgca aggattgcgg
     7801 taatcgctaa tacatctacg ccatatcttc ctgaacgtaa cgtcttgatc atttccaaaa
     7861 acatcaagaa ggcgagaatc cctccagtaa atgcgacaat cgcaaatgca agggccggct
     7921 ggtgaaaaac aaattcactt aataaagcta tcccaccaat aagcaaagta agtaaaaatt
     7981 ttttgaaatg tgtcattgtt ttttctcctc ttttatgtga cttagagagg ttagtaataa
     8041 atttccagct gcctctttca tcttaagcat agtccttgac tagcactttt taaaacaata
     8101 ggccttaatt gaaaacaact atcactatca gcgtttccaa aattcatcag ttctacaaac
     8161 aaaaatattc agcaaggatt actttttcga ttcatcagtt aaaaagtacc ttttttcgaa
     8221 aaactatgct atacttttaa ttcgttattt acggcggaag gagcaaacat gcgatgaatg
     8281 agaaacaact agaacaaacg cacgtggatg aaacgatcga actaatccag atcgaacaaa
     8341 atatgctgga tacaaaacaa caagaattga ctcaggaaat gaatcattcg acaaaagaca
     8401 cagctaatca caagattcga gctggttcca atgaagcttt ttatgaatct gctgttgaat
     8461 atcgccaaca tgagcaggaa ttgcttttga aataccatac tcttgaagca cagcaaaaac
     8521 gcctgcaaac gttgtctgtc atgaaagata gtccttattt tgcccgtatc gactttaaag
     8581 aagaccgtga aacagaaaca ttatatctag gtatcgcttc tttaagagat ctggcagaag
     8641 aaacaatcgt tattgactgg cgcgcaccaa ttgccaatct ttattatgaa ggtgagattg
     8701 gtcccgcatt ttatgaaact gaaacagata gaatagatgt cgatctgcag ttgaaacgac
     8761 aatttaaaat ccaagaagga cgtattttat ctatggtaga tacgtcggaa gtaatcaatg
     8821 atgacttttt gctagagata ttggatgaat catcaagcaa ccatatgaaa aacatcgtct
     8881 ctacgataca aaaagcacaa aatgcaatca ttcgggacac aacaagtaaa gtaatgctga
     8941 ttgaaggaat cgccggaagt ggaaagacat ccgctttgct tcaacgtatt gcttttctgt
     9001 tgtatcataa tcgcaagtgg ctcgaggctg aaaacgttct tctattttca cccaaccatt
     9061 tgttttctga ttacatctcg actgtattgc cttcattagg tgaaagcggc gtgcctacac
     9121 agacattcaa aaattatttg gtgcagctgc tgccagagtt ttctttacta gatgaacagc
     9181 aacaagaaag tggttttttg ctaggggaaa aagatccgat acaagtgatg aaaagcggat
     9241 tgaccttagt cgatcagatt gatcgctata tccaaggcat cacaaactac ggtcccttgt
     9301 tccgtgatat gaaaataaat ggccgtacga tcctatcaaa ggaatcgatt cgccaatggt
     9361 ataaagaaac aaatgaacaa ttacctttac atcatagact ttctctatta caaacgaagc
     9421 tcctgaaaaa attaggcggt ctgcaaaaag acgaaacacg tcagcaatgg gtcaaagatc
     9481 tggcggaaga acagctccaa gaactatacg caacagatcc aaatcttgaa tatacagaac
     9541 aaaaggagcg ttcattacgt aaaaaactgg ccaaccaaat cgtacgtaaa agattccgtc
     9601 gaatccatcg agggatcatg aattatcaat ttgtcaatat aacgaaacaa tatctccact
     9661 ttctacaaac tgtgccactt tctcttctaa cacgacataa aatcagcgag accaggtggc
     9721 aggaacattt gacaactgtt cgtacacact tgcgtcaaag agaattgcgt caagaggatg
     9781 ctgtactatt ctttttactg atgcgccgaa catatccagt gacggttaca cacaaagctc
     9841 gctatatctt tattgatgaa atgcaggatt tcgcaccatc acaagtggca ttgctgcaag
     9901 ccttgttccc aaaagcaaat ttgactttct gtggagatct aaatcaaaat gtctttggaa
     9961 atgaaacgat cgttggatca ttggaagacc ttttcgtgga ccgtgaagtc actcgtttcc
    10021 aattaacgac aagctatcgc tccacaaaag aaatcactga ttttgctaat cattttattg
    10081 tgaaagaaca tcaagtagaa acaacagcaa gaaaaggaga ccttcctttg ctcatccaag
    10141 gaacaacaga tgatatcaaa ttgaattggt tagcagatac cattcgaacg actcagggaa
    10201 aagcccggta ttggcgtaca gcaatcatag ctaaaacaca agaagaatgc gaagctcttt
    10261 atgctcaact gccagacgag ttgaaacaac aagtccagct gattttaaat gagagtgact
    10321 ttatgaagcg ttccattatt ttacttccag cctttttagc aaaaggtctg gagtttgacc
    10381 gagttttctt gtgggatgta gatgcagaac atttttcttc tcagcaagac aaattgatcc
    10441 tttacaccat gtgtacacgt gcgatgcatg aattgaccct ttttacctcc aataatgaaa
    10501 gtcctttgtt aaacaatatg gatatttcat cttatgagaa aaaagtactg taagtaaaaa
    10561 gacaactgct atcattaatg ttagcagttg tctttttatt tacaataata attgcagaaa
    10621 aagtaattca atcatttaag gtcatttatt ctatatataa atccaaatct gtttcaggat
    10681 attttaattt gacaagcgaa ataatcattt tcagttcttc catgttttct ggatattctg
    10741 ggtcaaatac cttgctatga cggccaatcc cgccattgtc gatcaatcgg taaattcgat
    10801 tccattcaat gaattggtca attgattgga aattgctgat tggatagccg ccacaatcca
    10861 aaatctctga tacacgaaat gctaggtatg cactatcgat cactttattt tttttcgtgt
    10921 ctatcttctc atttctttcg ataagaattt tttcaggacg atgtttcaag ctccactcta
    10981 atagtagaaa gaaagcctcc atccgatact cttcttcaaa taaccgaaag gctgaatcag
    11041 aacgacgaaa aagcagcgga atcagataat tttgtctata aatcagcatt ggtgcgcggt
    11101 ccaccataca ctctaaataa cggttcagat accctgtacc gacatagttt cctaatcgat
    11161 agccttcaac gccgaatctt gcgtattttt gcgctaattt tgaacaatca gttacgttca
    11221 cagctaactc ttctactttg cggtaaccgc ttaagatacg ttcaaaaggt tctaaagtga
    11281 tttttgcttc catattcttc cccgtccatc ttccacatac ttcatatcat ttcacatgat
    11341 acttatgctc tcatcatacc acaggttgaa ttagaaaaga aaataaatca cacaaaaaag
    11401 caagacaatc tgttagtgag attgtcttgc ttttcgaaaa agactgaata cttttcgtta
    11461 aaactggttg cttagtcttc taatgccaca ttatggaaca catgctgtac atcttctaga
    11521 tcttccagtg catcaatcat tttttcaaat gtttcttgat cttctggaga tagtgttacc
    11581 tcgttttgag ggatcatttg gatctcagcg attgaaaaat cagtgattcc tttttctttt
    11641 aatgcttctt gtatactatg gaaatccgct acttcaccgt aaacgatgat ttgtccttct
    11701 tcttccatta catcgcgaac atcgatgtct ttttccatta ggtattcaag gatctcgtca
    11761 gcgtcttctc ctgcaaaagc aaagattgct gtattgtcaa acatgtaaga aaccgctccg
    11821 gaaacaccca tgttcccgcc atttttccca aatgctgccc gtacgtctgc tgctgttcga
    11881 ttcacattgt tcgtcaatgt atcaacaatc accattgagc cgcttggtcc aaatccttca
    11941 tagcgcaatt cagagtatgt ttcatctcct gcaccttttg ctttttcgat tgctcggtca
    12001 ataatatgtt ttggtacatt ataagtttta gcgcgatcaa tgacgaaacg tagtttttgg
    12061 tttgcatgcg gatcaggatc acctgatttt gctgccgcgt agatttcaat cccaaatttt
    12121 gcataaatcc ggctattatt agcatcttta gcagttttct ttgctacgat atttgcccat
    12181 ttacgtccca tattttcact tcgctttctg atttgatagt ttcataacgc aaaaacgtcc
    12241 tgttccatta tacttgtgaa tcacgattct gtgaagcttt ttttctttct tccttcattc
    12301 ttctcatttt tagtcaatta tctatactcg gattgggatt tgcccgaaat tctgttccgg
    12361 aatattgcct cccaattgat agatttgatc acttctaact aacagttccg cttcttgtgc
    12421 ctcttttttt ccgattcggg aataaataga aatctctttt ttttctttta agaatcttct
    12481 tccagcatcg gtaaatccaa gtagtcgaag ataattttta ttttgttgga caggaatctc
    12541 ttgctttttg atattcagca agacataaca agataatcgt tggatccgtg tccatgtata
    12601 tctttttgtt tttacctttg acacaaaatc ctcaaaacta tcagcagttg cagctgctgt
    12661 tttcatgcgc gattctattc cttcggtcat ctgatagata tctgtcagtt ccagcaaagt
    12721 agaagataac aaccgataac gcaaatacgg ccaataagat tcccaagtct gcagcgaaca
    12781 agttgaaaga tcttcttctg tctgaggcgg cacaagtcca gctattcttt ttccttcttc
    12841 taacgcatgg cgaatggctg ttgcactggc tatcctctga tctgtgatga ttttttcatg
    12901 atagcctgca cttttacgtc ggatcggatg taattccata gggtggacat acttggcatt
    12961 ttcctttgca taacttaatc ccaagatatg atttggcgaa gaaaaatcaa gcgtaatatc
    13021 gggatacaga ctgcgaaaaa cctcagtcat tttttgcgga taactatacg tttgatcaga
    13081 cagttcttga aatgcctctt ctatcctatc ttgattctct tggacaaagc gtccgaaact
    13141 gctgtaatca aacgaagtct cttcttctgt tccaaaacac aaactgtcac agtccagtgt
    13201 ttgcaagatt tttactgcac ctttagcaaa atagtcagct gactgaaccg cccattcgac
    13261 gggaagctcc actactaaat ccacaccatt ttgtaaagct tcattcgcgc gatgccattt
    13321 atcgatgata gccggttcgc ctctttgcaa aaaattcccg ctcattacag caatgacgac
    13381 ctctgctcct gttatttttc gtgccatttc cacatgatag cgatgtccat tgtgaaaagg
    13441 attgtactct acgataatcc cgcagctttt catgcgcatc ctccttcata gttatcgata
    13501 aaaaagaaat agagacaagt aaaaaaaggc aaaaatcgga aaaaataccc gaactatata
    13561 aactattctc gcaaacacaa tacttctgcg acgaaaagct gcactgcaag agcaatgcct
    13621 atatcgttcg gatatataat ttatgttgaa gatttattct tttcttgtta actcgagcag
    13681 gcaaaaccgc tagtctttgt atgctacaaa gaaccagcgc tttgatttct ctgatgctgc
    13741 ttcgtctgta aaatcagaaa atgcttcgac tttcgaaaag ccgctgtttt ccagcattct
    13801 taaataactt tccaatggat aggtacgctc ttgatgtagt tcatcttcac gaataaatcg
    13861 accagaccct tcttgttctt caacgaaaaa ggtaagaaaa tgttcgatgc tgtgtttctc
    13921 gcttcctgga taactatccc acaaaaaagc aaaattatcc ccttgataat gatagctata
    13981 ttctggaaaa acctcatcta cttgataggt ggagtgtacg tcaaataaaa atcggccatt
    14041 ttcttctaac gcttgataga cttcatcaaa cacttgctgt acctcttgtc tatttttcat
    14101 atagcacagc gaatcagaaa aacaggtaat tgcctgatat tgtccgattt ctgataaatc
    14161 gagcatattg ccttccacaa attggatcga tgcgtcttct tcatatgctc gctggctggc
    14221 aatcatcaac atctcttctg aaaggtctaa ccctgtcact ttatatccat cttttgcaaa
    14281 ggcaaccgct aatgctccag taccgcatgc cagttccaaa atattttttg tgtcttcttg
    14341 taaatgacgt ttcgaaaaag ctaaccattg ctgataaagt gtttcgtcca tcacttcatc
    14401 gtaaatgaaa gcaaatgttt cataagccat atgttaatcc aaccattcac taagatcgac
    14461 tagcggagca tctgaccata gtttttccag attatagaaa tttcgttctg gcgcatggaa
    14521 aacatgtacg atcacatctc caagatcgat caatacccat tttccgcctt cttttccttc
    14581 aatacgtttt acttcatatt tgttttcttc ttctttatca atgatttctt ctgtaattgc
    14641 gttgatttga cgttcgctat ttgctgaaca gatcatgaaa taatctgcca acaaggaaac
    14701 atttcgaacg tctaaagcga taatgtcttc tgcccgtttt gaatctgctg cttcaatcgc
    14761 aatttttaat tgttctttac tatctatgat gatttcctcc taatatgagc agcttatttt
    14821 tttgctaccc agtaattata tgtttcgatt gtttttggat aaatctgttg ttcttgcgca
    14881 agcaaatggg ccaatgtatg ttttgtttca aatgctacag cttcgtctag atcagcccat
    14941 gcaatggctc gtgcatcttg taccccagga aaatctcgac ctggttcaat atagtctgct
    15001 acataaatga ttttgtcaag gagactcatc ttagcagccc cagtcgtatg cacccggatt
    15061 gcatgaagaa tctctgcatc ggtgattcct aattcccgct ctacaaacga agcgccaaca
    15121 agaccatgcc agattgcatt attataattc aataactccg gatcaaaacc gtctcttacg
    15181 attaccattt tgaactcctc atctggtcgt tcttttgcat aatcatgtgt caatgcagca
    15241 atactagctt tttcaggaga agcaccgtat tttttggcaa gagccacggc tgtttcttct
    15301 actccaagca catgcttgaa gcgttgttcg ctcattctca tctgtatttt ttgcatcagg
    15361 ttttctctag aataagcagt atattcatta ctatagtcca tattcataca acccttcatt
    15421 ttgaatataa tcaattactt tatctggaac aaggtagcgg atagaacagc cttctttgat
    15481 cttttgacgt attttcgtgg aactgatgtc gatctcaggt acatctaccc aaattacagg
    15541 atatggagta tccgttgtgt atcctggtcg acgtataccc acaaagttga ccatagaagt
    15601 cagctcatcg attttatacc attttggcaa atattctacc atatccccac cgataataaa
    15661 gtaataatct gtatccggat tgttttgcgt caattccttc atagtatcat aggtgtaact
    15721 tttcccacca cgagctaatt caatcgtttc aatctgcaaa aaaggattgt cttccaccgc
    15781 taattccaac atgttgagtc gatgttttgc atcaatcgtc tgtttctcat caacatgagg
    15841 tggctgataa gaaggcatca aaaatacgcg gtcaagacct aaattccggc cagcttgttc
    15901 agccatcact aaatgtgcaa ggtgaacggg attgaatgtt ccgcccaaga tccctacttg
    15961 ctttttcttc tctaagaatt gaggcatttc ttcaggaaat aattgtgaac gaacaaatgt
    16021 cttagcttgc gtattcatca tggtcactcc ttatattgct tttacttctt ttgatagcct
    16081 ttgatacttt tcttttgtgg aaggtttgta taatacaata acacgtccaa tgatttggac
    16141 gatttcgcaa tctatttctt tttctaatac ttgagctgct tcttctgcaa tctcatctgt
    16201 attttgaagt aacgatactt tgatcagttc tcttttttct aaagcttctt caatttgaac
    16261 gatcattgct gaattgatcc caccttttcc gatttgaaaa atcggctgaa gatgatgcgc
    16321 tttgctacgt aaaaaacgct tttgttttcc tcttaaactc ataattttcc ttcttcctta
    16381 aatcaatgct ttgcgtttca atacatctac accctttggc gcccagcccg caattactac
    16441 tggcgctgtt acagtgatcc agcctagacc ggcaaaaacg atgtctgttt tttctttcac
    16501 agaaaactca aaacgaacaa gctccggaaa tgcctcgact tcatcaggac gaggaggctg
    16561 taataatcca cctacatgtt tttgataaaa ttcgtctgct ttttccagtt tcgttcgatg
    16621 aatatttaca tcatttgaca cataagcaat aaatgaagca cgattgccgc tgataaaatc
    16681 aaatcttgca agtccgccca agaaaagtgt ttgcccttca ttcagctgat aaactttagg
    16741 tttgatttct tttaacggtg caatgatccg caaatctttt ttacctaagt agtgcgccat
    16801 ttgatggcga tggataattc ccggtgtatc aatcaaaaaa tgcccgtcat ctaaaggaat
    16861 ctcgatttta tccaaggtcg ttcctggaaa ctgcgaagtt gtgattacat cttgtactcc
    16921 cgctgtattt ttgatgattt gattgataag cgtcgatttt ccgacatttg ttactccgac
    16981 gatatagaca tcccgtccat cgcggtattc ttcgattttt tctaatagtt ccgtcatctc
    17041 atgagatttc ttagcactag ttaataatac atctactgga cgaattcctg cttcgtaagc
    17101 acgttccttc atccattgtg ttaatttagt ttttttcaat gatttaggta atatatccac
    17161 tttgttccca actaaaagta ctggattgtc accgacaaaa cggtgtagtc ctgggattag
    17221 tgaaccattg aagtcaaaaa tatccaccac attgacgatc aatgcatctt tttgccctaa
    17281 ttcattcagt aagcgcaaaa agtcgtcatc cgtcaatgag acatcttggg tctcattata
    17341 atggcgtaat ctgaaacaac gctgacaata gacttccccg gaagctaaac ctttttccaa
    17401 agccgtttgc ggcgtgtatc ctaattcacc gggtttgttt gtttgtataa cggcaccaca
    17461 gccgatacat tgtaattctt ctgtcattcg attccacctc gccagcccat atcagggtgt
    17521 tttgctaata gataggccat aattcttttt tcccaaaaac gattaaattg tgtcttccaa
    17581 ctatctgttg cgataatggg ttttacaagg atgctacgta tccctgcacg attggctcca
    17641 cgtatatcag tcataatctg atcgcctacc attactatct catcatctgc taaatccaat
    17701 tgtttctttg ctatgttgat ccctcttgct aaaggtttca ttgctcgtgc aacatacaaa
    17761 agatcaaatt tttcaatcgc tcgcgcgaca cgttttgaat tattgtttga aacaacaaca
    17821 acagggattc ctgcattttt catttctaaa atccaagtaa gcaactcttc tgttccatct
    17881 ggattattcc atgcaatcaa cgtattgtct aaatcggtca atactgcttt gatgcctaga
    17941 ttctttaatt gggcaggtgt aatctgatag atggcttcta ccatccatgt tggtttgtaa
    18001 tttgaaaaca tgctgtctcc tcatctgcaa aaaatgaagg agcacataaa gtactcctca
    18061 accccgtatt atactgcata tcagcaaaaa aaactacctc tatactcgtt cgtctttcag
    18121 aaaaagcatt tctttacaaa atgaccaaaa ataaagattg atcacagaaa aatttagaaa
    18181 caaaaaacaa ctaatattgg cggaacctct tgtatcgttt ttccagtaat ttatgctgat
    18241 ctaatcgaac aagttccgtc aatctttcaa tcaacgcttt tttcataatg tgtgcgactt
    18301 tatatcgtgg caactgctcg ccgttgaacg tttcaggaat aactcgatca acgattccta
    18361 actcgcgtag ttctggcgca gtaattttca tcaactcagc tgcttctgcg gcgcgactac
    18421 cgtctttcca caaaatcgac gcaaatcctt ctggagaaag cacagcataa atcgtttctt
    18481 ccagcatcca gacttcatcc gctaaaccta gagcaagggc accgccactt ccaccttcac
    18541 caatgatgat ggcgatgatc ggtaccttta aatcagacat ttcgagcaga tttctggcaa
    18601 tagcctctcc ttcgccgcgc tcttctgctc ctacaccgca atatgcacct gctgtattga
    18661 tcaaggtaat caccggtcta ttgaactttt ccgcttgttt catcagtcgt aaagcttttc
    18721 gatagccttc aggatgggga gaaccaaaat ttctgcggat attttcctgc agatcccgtc
    18781 ctttttgaat accgatcact gttaccggtt tgccatctaa tcgagcgatt ccaccaacaa
    18841 tcgcttcgtc atctgcaaat aaacgatcac catggcattc ctcgaaagaa tcgaagatct
    18901 cttcaaaaaa atccaagctt gtccatcgtt ctttagctct tgctaactga acgacatcat
    18961 gtgctgtctt atccacgatc tatccatcct ttctgtgtat gcaattcaag aagcgtatgg
    19021 attttctgtt tcaattccat gcggggaaca atctgatcga caaaaccatg agataataag
    19081 aattcagcct tttggaaatc ttctggaagt tcctgcttga tcgtctgttc gatgacgcgt
    19141 cttccagcaa aaccgatcaa gctttggggt tctgctagaa taatatcgcc ttccattgca
    19201 aaactggcag ttactcctcc ggtcgtcggg tccgttaaaa cagttagata aaaaagacct
    19261 tcattgctat gccgtttgac agcagcagag atttttgcca tctgcattag agaaaagatt
    19321 ccttcttgca tccgtgcgcc acctgaagct gtgaacaaga cgactggaag actttccttt
    19381 gttgctcgtt cgaataatct ggtgatcttt tctccgacaa tcgttcccat acttcccatg
    19441 ataaaattag gatccatcac tccaataatg aagggaatcc cctgaatggt tgctttacca
    19501 gtgaggactg cttcatgaag tcctgtttta tcttgcattt ttttaatttt ttccgtatat
    19561 tcgggaaatg ctagcggatc tttggttaca agatccgtat cccattcttc aaaacttttt
    19621 tcatcaataa tcaaagctag acgctgccat gcaccgattc gaaaagcgta tccgcaatga
    19681 gggcatactt tttcttcacc gatgtctttc gtataaagga tatgtttgca atttggacac
    19741 tttgcccaca tgttatcagg aacagatggc gagttagcag gtttgctctc tctattagga
    19801 ttgatccgaa tatatttctt tttcttaaac agagccatct atgcgcctcc tatctccgtt
    19861 tctggtgtcc aattcggtaa aaattcttct tgtaaaaatg ctgtgctgta atcacctgct
    19921 atgactgcag gatgactaat caaatccatc tgaaattctg cgttcgtgat gattccttct
    19981 gtgataaatt cacttaaggc tcgctgcatc ttcattaatg cttcaaaacg cgtatttcca
    20041 tggacgatta tttttgcaat cattgaatca taatatggcg ggatcgtata tcccgggtaa
    20101 actgcactgt ctactcgcag tcccatccca cctgctggaa gcagtaagtt ttggatcttc
    20161 cctggagaag gagcaaaatg gaaagcagga ttttctgcat taatccggca ttcgattgcg
    20221 tgtccttgga atactacttc ttcttgacac acattcaaag gctcaccggc tgctatctcc
    20281 acctgttttt ttactaaatc gattcctgtg accatttctg ttactggatg ttccacttgg
    20341 attcgagtat tcatttccat gaaataaaaa tcgccttctt catccatcag aaactcgatc
    20401 gttccggcat tttcataatt gactgcttta gctgctcgaa cagcagcgtc tcctagtgct
    20461 tctctttttg tttgtgagat cactacagaa ggagattctt ccagtacttt ttgattgttg
    20521 cgttgtaaag aacaatctcg ctcgcctaaa tgaatgacat gaccaaatcg atcacctaag
    20581 atctgaactt ctatatggcg agcaggataa atgatttttt ccaaatacat atcatcattt
    20641 ccaaatgccg ctgctgcttc ttgctgagct gaagaaaaat gctgtgggag ctcttctttt
    20701 gattgaactt tccgaatgcc tttcccgcca ccacctgcag ctgctttcag catcactgga
    20761 taaccaattc tgtctgctat ttccaatgct tcttctactg tagataatac accagtactt
    20821 cctggaatga ctgggacatt tgcttcttgc atcaattgac gcgcattgat cttatttccc
    20881 attgcatcga tcgttgcact tttaggacca ataaatgtga tattgcactc ttcacacatg
    20941 gaggcaaatc ggctattttc agataaaaaa ccaaatcctg gatgaattgc ttcggctttt
    21001 gtcacgattg cagcgctcag tacttcctga acattcagat atgaatcaac ggcttttgcc
    21061 gggccaatgc agattgcttc atctgctaac tgtgtatgaa gtgcttcggc atctgcttct
    21121 gaatatatcg ctacggtttg gatccctagt tcgcggcatg cacgaatgat acgtacagcg
    21181 atttcaccgc ggttagctat caatacttta gaaaacatat ttcacctatc caatcataaa
    21241 ggttaattcc gcttcggcta cttttttacc gtctacttta gcgattcctt tgcctattcc
    21301 ggctgaagct ttcactttca atatctcaac ttcaaggtat aaggtatctc ccggtgtaac
    21361 tttcttacgg aattttgctt tgtccaatcc gccgaaataa gccgtctttc ccttgaattg
    21421 ttcaagagaa agtaatgcaa ctgctcctgc ttgagccatt gcttcaacaa tcaatacccc
    21481 tggcataaca ggttcttctg gaaaatgtcc ttgaaaaaag ggctcattga tcgttacatt
    21541 tttcttagca acgatccgtt ctccttcaac catttcttcc actcgatcaa tcaaaagcat
    21601 tggataacga tgtggaatga tttcttttat ttcttgtatg ttcattgttt tccctctttc
    21661 ctgctttgct tatttttgct gaatcctaaa gagtggctgt ccatattcga caactgactc
    21721 gttttctaca aggatttctg tgatcactcc gtcggcctca ctagttatct cattcatcag
    21781 tttcatcgct tcaataatgc agataacttc tcctttggca acttgatcac ctactttttt
    21841 gaaagctggt ttgtcgggcg ctggttgcag ataaacgatt cccacgattg gcgaaacaac
    21901 ctcgattcca tcaaatactg ccgattcttt ttctttcatt atttctggag cagttgttgc
    21961 ttgttcaggt atgacattga ctggctccga aactggcaac gtttcgtttg tttgaaccat
    22021 attcatgcct cgacttgttt tatttttatt catatacaat tcaaattgac cttcacgcaa
    22081 atcgaattcc gttagcgagg attgatcaaa ttgactgact aattctctga tttcattgat
    22141 atccaaaatt attcctccca gcgtttcatg cacagaaccg cattatgtcc gccaaaccct
    22201 aatgaattac tcattgcata agtaaaactt gcaggtttgc tttcgttttt gacaactgtc
    22261 aagtcaatct caggatcttg tttttctaca ttgatcgtag gtgggataaa ttgatgttct
    22321 aatgccagca aagttgccaa ggcttcgatc ccgccggctg ctcccaataa atgtccagtc
    22381 atcgatttcg tgctgctgac gtaagtatct ctgaaatttt cacctaatgc gatttggatt
    22441 gcttttgctt ctgcctggtc attggctggt gtacttgttc cgtgagcatt gatatatccg
    22501 acttgttccg gctgtacacc agcttcttcc atcgcaagct tcattgcttt agatgcacca
    22561 gaaccatctg gagtaggagc tgtcatatgg taagcgtcac agtttgcacc gtatccaacg
    22621 atttctccat agattttggc accgcgagct tgtgcatgtt ctaaagattc aagaactaga
    22681 acgcctgctc cttcacccat cacaaaacca ttccgatttt cgtcaaacgg aatcgaacca
    22741 cgattaggat cagttgattc tgagagtgct gttaaagctg caaatccagc aatccccatc
    22801 tcacaaatcg ttgcttctgt tcctccagca agaatgacat cagaatagcc atgtttgatg
    22861 ttacggaatg cttccccaat tgaattcgtt ccgctagcac aagctgttac gatagctgta
    22921 caaatacctt ttgcacctac acgcaaagca atatttccag ctgccatgtt ggcaatcgcc
    22981 attggtacga acattggaga aactcgtttt gcaccttttt catgtagacg aataacttgg
    23041 ttttcgattg ttggaagacc accgatccca gatccgatga tgacgccaaa ccggtcttga
    23101 ttcatttttt ctttatctaa accgctcatc tccattgctt ctaaagcagc gtagattcca
    23161 tagatcgaaa acatatccat tcgtttgcta tcttttttaa taaaatattt atcgtaaggg
    23221 aaatctttga cttcacccgc taaggtaatc cctgtttctg aagcatcaaa tttagtgatc
    23281 ggtgcgatgc cattcgtccc ctcttttaag ctattcaaaa agctgtctgc gtcatttcca
    23341 ataggtgaag tgactccata gccagtaatt accactcgat tcatttgttt gctctccttt
    23401 tcttatccgt gcatgaccaa tccgccatcg acattgatga cttgtccggt gatatatgga
    23461 ttttgtgcta agaaaactgc tgtttgtgca atatcttcta cttgtccgaa acgctgcatc
    23521 ggaatttgct tttccgcttg ttccttgact ttgtctgcta aaacttccgt catatcagtt
    23581 gtgatgaatc ctggcgcaat ggcattacat gtaatgcctc tagttgcagc ttctcgtgcc
    23641 acagattttg ttaatcctac tacgccagct ttactagctg cataatttgc ttgaccaata
    23701 tttccaatca acccagatac actagagaga ttaatgatgg ccccttctcg ctgcttcatc
    23761 atttttttca atacgtgctg cgtcatattg aaggttccaa tcaaattgat atccagacat
    23821 tttttgaaat cttctgcatc cattcgcatc acaagtttgt catttgtgat tccggcattg
    23881 tttactaaca catggatcga tccaagcttt tcttctgctt ctttgatcat ttgtcccgct
    23941 ttctcataat cagagatgtc accggaaact cctacgcatt ttacaccgaa tgcttcgatt
    24001 tcttctatct tttcttttgg aatctctccg cgaccattca aaatgatatt tgctccagct
    24061 tttgcaaaag ctaaggccat cgctttgccg attcctcttg tactacctgt gataaataca
    24121 ttttttcctt ttacatccat aacgttcctc cttatagtat tgctattgtt tcatcaaatg
    24181 tctgcttatt ctcaacacgc agaactggta ttgttttatc gatttttttc ataaatccgc
    24241 ttaatacttt tccggggccg acttcgatga cttgttcgat gccgattgtt tttaacttat
    24301 ggatactctc atagaaacga acaggttgca tgacttgctg ttcaagtagt cccgcgattg
    24361 tttctttctt cattatttcc gttgttgtgt tgcttatgat aggaaaagaa ggttcagaga
    24421 attgaatctg acttaggtcc ttcgccagtt tttttgctgc cggttctaaa atagctgtat
    24481 gaaaaggccc gctgacattt agagggatca ttcttttgaa ccctttttct tttaatagta
    24541 aaacagcttc gtctactgct ttttcttcgc caccaatcac gatctgctga ggtgtattat
    24601 aatttgcagg agatacgatg ccgtacttgc tagcttcatg acagctttcc tcgatcgttt
    24661 caatcggcgc attcatcact gcaaccattt tcccgcttcc agctggggca gcttctgtca
    24721 tataagcgcc tctttttgct actaacgcaa ctgcttcagt gaaggatagc gcattactag
    24781 ctactaatgc cgaatattct cctaaactca gtcctaaagc tgcatctggg atgattccat
    24841 gctccttcaa taagcgataa tacgcgatgc tgactgttag aatagctggc tgtgtatatt
    24901 gcgtctgatc caaacgttca ttttctgtaa agcaaagttc agccatatcg tagccgagaa
    24961 tctcacttgc ttcatcaaat gtctgcttta caacggcttc ttcatataaa tcttttccca
    25021 taccttgata ttgtgcacct tggccactaa ataagaatgc tgttttcatg tttttctcca
    25081 atatatccag aatatatgtt tgattcttcc tattcaaaaa ggccgagaca ttcctatttc
    25141 aggaaatgtc ccagccccca acctaatttt aatgattatg cagtttgttt ttctacgtaa
    25201 gtcactaaat cttgaaccgt tttgattccg tcttctgttt cgattttcac gtcaaattca
    25261 tcttcaattt cattgatgat ttggaataaa tccaagctgt cagcttctaa gtcttcttgg
    25321 atgtcagtag tcaatttgat ttcttcagtt tcttttccta attcttctgc gatgatttct
    25381 tgaatttttt cgaataccat aataatatat tcctccgata ttgtttgctt tttattttta
    25441 taatttaaca gtctacaact ccatgagaat acttccccat gttaaacctc cgccatagcc
    25501 tgtaaatatt actttctgct gttttcctaa ggtgatcttt ccactagaaa ctgcttcatc
    25561 caataagata gggatgcttg cagcagatgt attcccatat ttatccatat tggtcaggaa
    25621 cttttcttgc ggcatcttta cttttcgggc aattttctca ataattctga ggtttgcctg
    25681 atgcaaaagc agataatcaa ctggtttgtc tttcatgact tcttggatat tgtttgcaac
    25741 gtctcgtacg gcaaaatcaa aaatatctct gccagtcatt tgcaaataat acgaaccttc
    25801 tgaatcttct gaatagaacg gatttttatt ttgctggtag ccagcggtca atgagctact
    25861 tctggtaccg tcagctgcta atttttcttt cagcaatttt ttctgtggat tcgcttctaa
    25921 gagaatccca cctgctccat cgccaaacaa cacagcagtc gtacgatcag accaatcgat
    25981 tagcttagat agtgtttcac caccaatcac cagtccctta gttgagccgc agcggatcat
    26041 tttttcagcc atgcttaacg cataaacaaa tcctgagcac gcagcactga tatcaaaagc
    26101 gatagcatga gttgctccca atttcccttg tacttgtgct gctacagatg gtgtcgtgta
    26161 atcgggcgac attgttgcta ctaaaataaa atccaaatct ttagggttta gatttttctg
    26221 ttttatcaat ttttccgcca ctaaaatgca taaatcagaa gtctcctgat ttgttacaca
    26281 tcttcgttca cgaatacccg tccttgacga aatccattca tcagaggtat ccatcatctt
    26341 ggaaagatca ttattagtaa taatcttttc aggaaggacg ctggctgttg cagtaatcat
    26401 tccaaattgt tccattaaat atcctcactt atagtcttgc aagaagtcgt gcaagttttt
    26461 cagtgcatcc agcaaggcat gctgttcctc cgtagccatt ccgtctaaga tgttcttgac
    26521 catttcacga tgaaaatgct gatggacccg aaatagtaac tttccttttt tcgttagtcc
    26581 caactttaca acgcggcggt catcttcact gcggatacgt tcgacatagc ctttttttac
    26641 taacttgtta atagcagtgg tcaaggtccc aacagtaatt gatagttctt tggctacttc
    26701 tgaagttgtt tttttcttgt acatcccgat tgcctcgatc gtgtgcatct ctgtgattga
    26761 cagatctttg aattgagatt ttttcagctc agactcttcg attgtcaaaa tatcattgaa
    26821 gacactaaca agataatcat ttactgtttt taaatctggt tccatgttcc accgtccact
    26881 aattagtttg attatcaaat cttttgatgt tcaaactata tcttaacttt tttcaaaatg
    26941 caaccttaaa agatcatttt tttactatat gagctttttt taagatttta ctca
//
LOCUS       DACGEU010000035        25982 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.035, whole genome shotgun sequence.
ACCESSION   DACGEU010000035 DACGEU010000000
VERSION     DACGEU010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25982)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25982)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25982
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.035"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..936)
                     /locus_tag="IXR40_001361"
     CDS             complement(<1..936)
                     /locus_tag="IXR40_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BppU family phage baseplate upper protein"
                     /protein_id="HAQ4361219.1"
                     /translation="MAHVIKKGSIKVPTQPKDYDLQATGLVFKSYDNQIALEFNVEQQ
                     NGTPADLLGANLRLLMFIYDEVDGMITKEPIPFITKNLITESFLNGQVVYILPEAMKA
                     YNGMVEAYVYIEYPDGSTSDNLGFTFRMKRSAIDGLAQDKADYFIADFQQLLDGVKQE
                     ATDAVNAALTNVDSTIEKANQQINEFVEGATQAIDQTVDEVTEQLQATQTKIDTVSQN
                     VTSAQNNLKAVEDKMNQTNQQIGDLGKLKKMYSNSIDFGNYDYSGNPNLMSKLKSSDF
                     NVGYHGSLTSDNEKLHFTSDGTGSIIMFTRINTPQL"
     gene            complement(936..1718)
                     /locus_tag="IXR40_001362"
     CDS             complement(936..1718)
                     /locus_tag="IXR40_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361220.1"
                     /translation="MLDFQSKPNIFEEMSYEEAVKWLLRQAAIHYDGSDHDAHVLATE
                     SNAGFATPETVMQARGRWLRDYKLPQKYPNILDIPPGKYATKAGWGADNPDGIEDDSF
                     VEMMVFADHDSRKLIVAFARYSGEIYIKMTHNSEPVEGYNSLGWRRVYTTSVLFEGEL
                     RKGQSVNLPDDTFRYQTLRIHYTDGDGDFVEEVKRQRYARITKANLWNGDAGVTFIEF
                     ELTIEARKITMSNGRALDISSGNVSNPAMSNNVKITKIEGVK"
     gene            complement(1735..3492)
                     /locus_tag="IXR40_001363"
     CDS             complement(1735..3492)
                     /locus_tag="IXR40_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BppU family phage baseplate upper protein"
                     /protein_id="HAQ4361221.1"
                     /translation="MQETTSISKGGIVMAETQHKMVLSTTEPNNGINLVRIRQGDVLT
                     QKFVVEVVEHGKLKTFEGLVPFFINTTKFGENQPVEQKVQEYSPAQARLVYTLSEPDW
                     QWGGENTAHFSFRSLNGDGTWSEQFSTQDFTYRVISGISRSQLRDSGYVWTFEDLLRK
                     FKDYMDQGKNDWEQWLEDNREILENIDPGGMIINILNEAKGDYESLADRLNQKYQVPV
                     GSSQIRETTRFFDYDTMKYVDLVPRNLNTVVNSVNNSKFNFSFITDIHADNHNLRIDG
                     VGYKDASYLRHWRAIPQFQKLGNKTDVMIYGGDNIDGGLGSLGSDIGIIDEWSARHSM
                     LGTLKRFTNAAVAGQEKPVIICKGNHDACFDPAWRKRKGMLCNADFEEYWNGLYGGVL
                     FPDKNAAIYRFDTCDFYEGGTGDKYVDGYSDTAPGAFSAKQINAFGEWLVNVPRNYHV
                     ALVGHTPLGLSKFPVRNENMISTLIEGFKSGSPVTIDWSKLGQPNDGSFGGLKTFAMN
                     TKGAGVVVGYFCGHWHEQVEGAFGTVKMILCDVGFSHTASQVDTPDELAFYKIEVDTA
                     TRKVTSKGVGRARDFTYNY"
     gene            complement(3467..6298)
                     /locus_tag="IXR40_001364"
     CDS             complement(3467..6298)
                     /locus_tag="IXR40_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HAQ4361222.1"
                     /translation="MSETVYFFDHLQKLIKRKNTRSLIEVSQEKEISSDKSDLMKDTL
                     YVTTKYDKEIEDARYMAIRENESSFSLYRITKVSDPFETLEFTGLGFATNELDAYIIK
                     DIRPSGQPLKNVLDRLIEFTEGNWRVGHVEAMLPTVTATFYYVSVKEALKELQTLGME
                     FVFRCSLNSDGIKDKWIEVYEQIGEESNTRFVYGSKALTVVREIDRSSISTSMIGRGR
                     GEEVGDGYGRRIEFTDVEWKKSNGDPLDKPKGQNWLEDPESTQKYGIPQKDGSMRKRE
                     TVVVFDDIDDPTDLLKNTYSTLIDSARPLVQFKAEVTGGDVIGNTVTIHRYDKGYHYK
                     TRIYKTTFNRLTGQTNIELGDNLTQDVRKQTASIVNNINSLESSKMTFYESTEIGKYQ
                     DDIMRGAGDNGGSIYWVNGIEAGVSDSREIYETVYMDGPNIPRSRFFMVQNNSGISFK
                     QCKKGEWQTIQDVHNGDSTTAWTLDGTFNANFIRAGILSGILVQGVALKTFDDKDFQL
                     VAEGGELSFEKQVKSTGLDDVHGERLGSIVSTYGSKGINGFAVWKEPNYIFSINAGDG
                     GDRGNPIFQIPADVTADKRKYNLYGDGNFSEGNITIDGRLDVKELYVNGTKIDTNGGG
                     NSGGNDNGWNGQYPPEVTTDRDKRYWQIWATAIGAGFTQQAAAALLGNAQGESDANPT
                     ADEGNGAPGFGYGVWQWTDSSGATSGRVYMINLMTKAGISDDPDTITAQFKLLMWHAP
                     NGQWIATSAYPYTWTQFMNLTDINTAAQAFVANFERPRDPHPERTAWSQEWYDKFKDL
                     EIPVSKGYMKPIADPITVTSEFGWRTSPITGAQEFHNGIDLVNGNPNTPIFASADGEV
                     IVAGDANYFDWYGNWTVIKHADGMYTGYAHQSRVDVSKGQKVTAGQQIGLMGTTGPST
                     GEHLHFQFMDEFYPSSSGHFHNARDYIDF"
     gene            complement(6295..7062)
                     /locus_tag="IXR40_001365"
     CDS             complement(6295..7062)
                     /locus_tag="IXR40_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAQ4361223.1"
                     /translation="MYSFKDTTINLTSSKRFLPTSAMMYDGMYLEDLIDGYQTLTVEG
                     REMLSVEVEQQEIQIGSIITNQKIPSRTLKITYKLEDRDPEKLQFKFKELLNYLYRNE
                     DVEIRFHDELDYYYYGRYTSTDTVPGDSNSIISSFNVFCADPLKYTKECVSDGYIGNP
                     IQFPITPRKIEVTLSMNNSIKITNGEQNITITDAAIKTGDVLVFDFSDEQVTVNGEDC
                     TSMIDLESDFENFYLKQGQKITSNNGKLKIFYRGATI"
     gene            complement(7095..10214)
                     /locus_tag="IXR40_001366"
     CDS             complement(7095..10214)
                     /locus_tag="IXR40_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HAQ4361224.1"
                     /translation="MEQFSVEALLKATDSGFVKTFKDAQDAVKTFEKNSNSMTTAVGK
                     VMQGTGAAMTKYITTPLIGVGVAAAKVGGDFEAQMSRVKAISGATGDTFEQMKQQAID
                     LGAKTAFSAKESAAGMENLASAGFSAQEIMKAMPGLLDLAAVSGGDVALASENTATAL
                     RGFGLEASEAGHVADVFARAAADTNAEVGDMGEALKYVAPVANSMGISLEETAAAIGI
                     MSDAGIKGSQAGTTLRGALSRLARPTKAMQDTMDNLGVSFYDADGKMKPLKTQVELLK
                     KAFEGLTPEQQQNALVTLYGQESLSGMMALIDKGPDSLGKLTKSLKDSDGAADDMART
                     MQDNMNSSIEQMFGAFESAAIVIQKILAPSIKKVADAISGLVEKFVSAPESTQKLVVA
                     IGAIVAAIGPLIFMIGSVIIWINRVKVAFKALSESSKLFSGLSKAMGLLTNPVFLVIA
                     AVALLVVGFIYLWNTSEDFRNFWIGLWEGIKSAVSSAVEWIQNAWKSTGEWFNNLWKS
                     IKEGADNVWTTVQEAPGKAADWIKNKWTGTKEFFSNLWSSIANSASEIWNSLKEGVIS
                     VIDDLVSSAGEKWEGFKNTISTAWKTITSKIKSGFDFILKYIGPFVSSFSDVFSNIVK
                     AITSIFAEVKNIIVNAWEIIKSLIAAPLLFIIDLITGDFEQMKEDLDLIWNTLVQSVV
                     NIWTSVKNIFTEYIGAIVNSAVSLWTGFIQSISNIWNEVVYQATMIWIDLKLFFTNLW
                     IDIKYSAIQMWINLKFSIIQTWIDTKYGAIELWNNLKQWFFQTVNNIVQTLIKSWNSL
                     KQGTIDLFNNTVQGAKDIWTSFKSWIGDLITGTKDNIIQGWENLKQGTIDTFNNLVNG
                     AQEAWDNLVNAVSDTVDRVTGWFDNLKNIDLLAAGKAIMDSFLEGLQNAWKSVQDFVG
                     GIGDWIREHKGPIQYDRKLLIPAGQAIMNGLNKGLTGGFNDVQNTVGSMADFIAELFN
                     ANSDVDIAANLKNANKNIGAQVEHKINMGGSTKPAVFKINLGRQSFRLFMDDISQAMG
                     EGADINLEF"
     gene            complement(10231..10518)
                     /locus_tag="IXR40_001367"
     CDS             complement(10231..10518)
                     /locus_tag="IXR40_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361225.1"
                     /translation="MTNISDIERMTLYEYNIRMTAAQLSWLDKEKLIHELAWANQQVQ
                     AEKKVGKKTVPVYRSFEEFFNYQKIEDSIMGVSELSKQDKKFQSLLTKANS"
     gene            complement(10572..10940)
                     /locus_tag="IXR40_001368"
     CDS             complement(10572..10940)
                     /locus_tag="IXR40_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361226.1"
                     /translation="MKLKIKGKEYSFKFGTKFVRELDKVMPFVDGNMEFGMGLSAKVL
                     PELRSYNVNTLSRVLEIANRTEDESITLDELDDYIDEVKDIEKLFDEVLKELAESNAG
                     KLAVRNLNQKLKEAEKQQVE"
     gene            complement(10986..11498)
                     /locus_tag="IXR40_001369"
     CDS             complement(10986..11498)
                     /locus_tag="IXR40_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail protein, TP901-1 family"
                     /protein_id="HAQ4361227.1"
                     /translation="MEALKGIDVILLYRLLKKETQEAAWKMAFQTEHENGLSRDSDST
                     VTKDGNVQSLSPVEYDFSATSIVAKGDSHVDEMKQALLNGDIIEIWEINKAEQGTDDN
                     ANKYKATYYQAYVSEFTPSAAAEDNVELSLSFAVNGVGQDGYATLTEDQADVVQYAFK
                     DTVKATSTGA"
     gene            complement(11509..11901)
                     /locus_tag="IXR40_001370"
     CDS             complement(11509..11901)
                     /locus_tag="IXR40_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
                     /protein_id="HAQ4361228.1"
                     /translation="MIKTRDQSIFDELFKISQNKLGYKTYDYKTLEDVGYPFVEFENT
                     QTIHEVNKTDIKGSVIVVLSVWGLQKKRKQLSDMASALFNEARLIEATEGYYWALNYQ
                     ASGIQVMDDTTTNTPLKRAVVTLEFRIR"
     gene            complement(11901..12239)
                     /locus_tag="IXR40_001371"
     CDS             complement(11901..12239)
                     /locus_tag="IXR40_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HAQ4361229.1"
                     /translation="MKAQLEYKGIDQLMRHLKKAATLNDVQKVVKSNTAEMTERMQKG
                     APVDTGYLRRSINMNLLEAGLTGIVGPTADYAPYVEYGTRFMSAQPYVRPAFNYQKVK
                     FMAEMKALVK"
     gene            complement(12223..12549)
                     /locus_tag="IXR40_001372"
     CDS             complement(12223..12549)
                     /locus_tag="IXR40_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361230.1"
                     /translation="MRFTDEIIFVKRSSDSKYDPDLGEWVEGKPERTRTEANVTDIGT
                     DRSVTIFGSVEEGAKVIRTQPLFSIPTFDYIEIEGKTWQQKTARNPAYRNSLIVQEVV
                     LDEGTT"
     gene            complement(12546..12875)
                     /locus_tag="IXR40_001373"
     CDS             complement(12546..12875)
                     /locus_tag="IXR40_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HAQ4361231.1"
                     /translation="MMIADDIKKLLKGTIDEKLEVIERRTNERMKTLLNTQEVPKEFE
                     TVVYEVSLKRFNRIGQEGMQSYSQEGLSMAFPDSDFSEYQNEIDEFKRKDQEELYKPK
                     RGRFKFV"
     gene            complement(12887..13150)
                     /locus_tag="IXR40_001374"
     CDS             complement(12887..13150)
                     /locus_tag="IXR40_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361232.1"
                     /translation="MPNQKTWTGKVGDTKTFTISAVPADASDAAAVVAATTATSSDGA
                     IATVTKNENGGFDGTIAAEGSATFTFTSGEFTTSINVTGQPAS"
     gene            complement(13168..14091)
                     /locus_tag="IXR40_001375"
     CDS             complement(13168..14091)
                     /locus_tag="IXR40_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HAQ4361233.1"
                     /translation="MKKKQLLPMNLQMFAQTWDPDNVLVYETKEGKIPDKYNTLILSE
                     VMENSKIMQLAKYEEMTDKEKKFEYFAEGPGAYWVGEGEKIKTSKPKWMQATMTAKKL
                     GVILPVSREYLNYKLSDFFEEMQPKIAEAFYKKFDAAALLNKENPFPQSLDGSVISAG
                     NVVEGGLTYDNILALEDKLAENEFEPNAFISNRKNRTELRSAAQTVGSNVEFIYDRST
                     NTIDGLPVVDLKSLDKGTLYAGDFNYMFYGIPYNISFKISEEAQLSTLTNEDGTPVNL
                     FEQELIALRATMDVGFMIVKDEAFGKISPKA"
     gene            complement(14104..14706)
                     /locus_tag="IXR40_001376"
     CDS             complement(14104..14706)
                     /locus_tag="IXR40_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HAQ4361234.1"
                     /translation="MKKRLFMPMNLQFFSEPGDGGSGDEGQQGNLPAGSQETPPEAKE
                     ENNTGKTFSRDEVAKMIAAETNKAKAAWEKELAAKKEEAKKLAKMNAEEKLQHELEQK
                     EAEIAELKRGQALSEMTKEASKMLTDANLPHDDDLLGLIVSDDADATKQAVAVITNFA
                     SLIKRENARQTPPNEGGQFTASKNTKETVAKLAAKNRIIK"
     gene            complement(14833..15759)
                     /locus_tag="IXR40_001377"
     CDS             complement(14833..15759)
                     /locus_tag="IXR40_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head morphogenesis protein"
                     /protein_id="HAQ4361235.1"
                     /translation="MNSQEYWIKREKEWQKQQIKDDKKRMAEIKSRMQYAQDAIQKEI
                     DAQWDSFSNGQKITRSEAMKRASEMDVKAFARKAKKYVKEKDFSPTANQELKLYNLTM
                     RVNRLELLKANIGLELISLFNELDKYFSNELTKAGLAELKRQAGILEMTIASSGYAKL
                     IELVINSSFLSDDVSFSDRLWMYQSELKSELDRLLVRSITMGKNPKQLASKLAEYLTA
                     EGRENTKFNTQRLMVTETTRVQVGIQERSYRDAGITQYIYIAEPTACKLCIPLNNQVF
                     DVADMQPGSNAPNMHPFCRCSTAPYIERISSR"
     gene            complement(15764..17263)
                     /locus_tag="IXR40_001378"
     CDS             complement(15764..17263)
                     /locus_tag="IXR40_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HAQ4361236.1"
                     /translation="MDKVNEFEYGADIHYSNDVNTNYVKFSVDSNLHYRFSSAEDLLN
                     DLDTLAAMIKHHHEYQVKRLSVLDDYYKARNTNIMDNRRRREKEKADHRSAHNFGKVL
                     CTFDVGYNTGNPIKVQIEDTNQQKEIEEFNTNNDIDGLNAELWLDMDKYGRAYEIIYR
                     DSDDTDYVDLANVFETFVVYDTTVKREPILAVRYPKTRFNKDADKQYIQPIVYTKEKS
                     ITYDETTLTAIELKNPQDEPHEYKEVPITEYSPNRFRMGLYEDVLSLIDLYDAGQSDT
                     ANYMTDLNDALLVISGDIEAAGLSTEDAIKQKEANMLLLESGTDVNGNKTSVTAGYIY
                     KQYDVNGVEAYKYRVRKDIHEISMVPDLTDDNFSGVQSGEAMKYKLFGFEQMTATKQR
                     LFKKGLMRRYRLLFSLKSSISEMDNSDLKGLRVIFTPNLPKAILEELKSLVDAGAELS
                     QETILGLASFVPDVQAELKRVNKETQKQIGIFDSDGEEVINNKKDETGG"
     gene            complement(17276..18520)
                     /locus_tag="IXR40_001379"
     CDS             complement(17276..18520)
                     /locus_tag="IXR40_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HAQ4361237.1"
                     /translation="MALVDIYNPKQIDVLNKTIKNDWFITLLHGAKRSGKTKINNDLF
                     LFELRRVRKIADEEDIKEPMYILAGVSSATIQKNILQELYNMYSIEPKFDKHGNFKLF
                     GVKVVQAYTGNIGGVGAIRGMTAYGAYINEASLARQEVFAEIVSRCSGTGARILADTN
                     PDNPEHWLKKEYIDNSSKNIQSFHFELDDNTFLSERYRNNIKESTPSGMFYDRDIKGL
                     WVSAEGVVYRDFDASKHYIQSKDLPPLSNFYCGVDWGYEHWGSIVVIGETDDGTAYLI
                     EEHATQFEEIDYWVDVAKGIQERYGLRVPFYCDSARPEHVARFVREKINAKNAHKARL
                     SGVEEVAKRFKQDKLFICQDRVMKFRDEIYQYIWDKKKGEPIKEYDDVLDSVRYAIYT
                     HELLKKPKVNVNEKIKRIKRMF"
     gene            complement(18507..19040)
                     /locus_tag="IXR40_001380"
     CDS             complement(18507..19040)
                     /locus_tag="IXR40_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HAQ4361238.1"
                     /translation="MVNLTPKQKAFADEYIKNGGNATQAAIKAGYSKRSARVIGKENL
                     TKPNIIQYINERLNPIEKKRKLSAEDALNELIDIWQGEVQISVSKQIDRLEKNKVIKH
                     MQYEYTPDLESKLKALDLYLKYKSLLSQTQLEKAQTEIKLMQAKLEQLQINSERSTEE
                     KLDELLEKISGELDGTS"
     gene            complement(19067..19291)
                     /locus_tag="IXR40_001381"
     CDS             complement(19067..19291)
                     /locus_tag="IXR40_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361239.1"
                     /translation="MRNYWYVSLSNKYPQPNADDPIRVVQSVQIKKKYSIIEMTREAT
                     PKEIDKYNLRYCGHGYFSEQNIQTNIERYC"
     gene            complement(19298..19510)
                     /locus_tag="IXR40_001382"
     CDS             complement(19298..19510)
                     /locus_tag="IXR40_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361240.1"
                     /translation="MNENQLRELFKTNEANKTMEATFYETQKSLALIAKQAKYFYDQL
                     ILQGFNDAQAMEFMMRTFSASNQQKE"
     gene            19872..20051
                     /locus_tag="IXR40_001383"
     CDS             19872..20051
                     /locus_tag="IXR40_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegP family protein"
                     /protein_id="HAQ4361241.1"
                     /translation="MYFVIREATNGQYYFVIKSDNNEVVATSETYLTKYSAEQTINSI
                     KNGITKDSQVIDVTK"
     gene            complement(20044..20385)
                     /locus_tag="IXR40_001384"
     CDS             complement(20044..20385)
                     /locus_tag="IXR40_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361242.1"
                     /translation="MEVEQIKYQGMDRERLIDIIEQQRLELIQKEAVCKEYKKHLEQV
                     IEYHSVEKYRSVVQKNRATSPDPRQDVSISIKTPVFNSVKSEKLESISTALVEKAAEM
                     NSLANEVSRLI"
     gene            complement(20684..21151)
                     /locus_tag="IXR40_001385"
     CDS             complement(20684..21151)
                     /locus_tag="IXR40_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HAQ4361243.1"
                     /translation="MVLFDVKKYETPEAKDVDMDRTKHNVGVFLSAYLSARCRIGQPR
                     EPKVTASYSLVPPSTANNTFEAERMMIEREEAQEEFEYLHKLFVRGYSAIQHPHKPDV
                     TERRKKIFYDRYINGLPIYVTAQRNNTSEESVKVESNRIIIQFASSLELVAFK"
     gene            complement(21743..22030)
                     /locus_tag="IXR40_001386"
     CDS             complement(21743..22030)
                     /locus_tag="IXR40_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012197617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361244.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKKRKKPKFKVGDMVRCEA
                     EGFIYPFRGYVEHVYNHSAIIRIENTMECDKWLAKSKENLAVARLVDMKAI"
     gene            complement(22027..22236)
                     /locus_tag="IXR40_001387"
     CDS             complement(22027..22236)
                     /locus_tag="IXR40_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361245.1"
                     /translation="MKIYVVKFGNKFYRSDERSIGANTLFIVDILQSARWFDSLEEAN
                     QVSRRLGGLTQVYELVTVDHEEVER"
     gene            complement(22233..22430)
                     /locus_tag="IXR40_001388"
     CDS             complement(22233..22430)
                     /locus_tag="IXR40_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361246.1"
                     /translation="MKAYTIKFYGNKTYVYILSGLRLDFRGYSKEDLLESLYGYGYLN
                     EDELISLEKFTNAWTIEEEAE"
     gene            complement(22427..22753)
                     /locus_tag="IXR40_001389"
     CDS             complement(22427..22753)
                     /locus_tag="IXR40_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361247.1"
                     /translation="MNYTQQELTDLCPKHVAEFINNEVLPKYADGLNTAENVTDFMIN
                     DAIDRLIFLEIDCIAYYRLHAEVALIDPYIALSQNRKILVAYIDTKQILEGRDVEIEI
                     DEEEVG"
     gene            complement(22750..23031)
                     /locus_tag="IXR40_001390"
     CDS             complement(22750..23031)
                     /locus_tag="IXR40_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361248.1"
                     /translation="MGDMGEYWKDIKPHLKERRKQHVRKMGNSATKNIETLGFEFTHY
                     PNNHQFAINTHNGIIDYWGTTGTWIERKTKKRGKGIRSLRKYINQEDSK"
     gene            complement(23044..23262)
                     /locus_tag="IXR40_001391"
     CDS             complement(23044..23262)
                     /locus_tag="IXR40_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr domain protein"
                     /protein_id="HAQ4361249.1"
                     /translation="MISLTIFWCVIGGLLAMLGAYLIYESAKGKKYTAVGIILFVVGI
                     LVAIGAEINLYLNGTTEELMWFLLWTRR"
     gene            complement(23259..23570)
                     /locus_tag="IXR40_001392"
     CDS             complement(23259..23570)
                     /locus_tag="IXR40_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361250.1"
                     /translation="MDELITKVEQWAKDKGLDQADSSKQMLKTIEEIGEVAASLARKD
                     EHGLRDGIGDVVVTLIILAMQNDMDLYECLNQAYNEIKGRTGKMVDGVFVKSSDLEDS
                     K"
     gene            complement(23747..24061)
                     /locus_tag="IXR40_001393"
     CDS             complement(23747..24061)
                     /locus_tag="IXR40_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HAQ4361251.1"
                     /translation="MDLITQYSDIILKKIMMKIQKDKKAKERAELVKLEMAETGAGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVEKYREILNEYFE
                     ED"
     gene            complement(24061..24366)
                     /locus_tag="IXR40_001394"
     CDS             complement(24061..24366)
                     /locus_tag="IXR40_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361252.1"
                     /translation="MSVGKKAAMKRIIELTHSENWQEDKEIVAEVQKLGKSMWTEKPK
                     RKTPRKIAIWHGDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEK"
     gene            complement(24363..24524)
                     /locus_tag="IXR40_001395"
     CDS             complement(24363..24524)
                     /locus_tag="IXR40_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HAQ4361253.1"
                     /translation="MTTEEVIQMRIRSLQREIDDLERIKAVMVNETARKAINLHIVNL
                     RREIRRLEE"
     gene            complement(24539..24898)
                     /locus_tag="IXR40_001396"
     CDS             complement(24539..24898)
                     /locus_tag="IXR40_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HAQ4361254.1"
                     /translation="MNKYRNKKTVHRGIKFDSIAEAEYYDLALWQAEANGWKVKLQER
                     FELMPKFELDGKKYRKIEYIPDFTFYKNGKLVKVVDVKGMQTKDFKIKAKLFCHQYQV
                     PLILAKKYRNTFKEERF"
     gene            complement(24895..25746)
                     /locus_tag="IXR40_001397"
     CDS             complement(24895..25746)
                     /locus_tag="IXR40_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAQ4361255.1"
                     /translation="MESLANAMEKLIRRVLVQSGKCPECSEPLYSWRAKNKDGSERCK
                     PTCMSCGYKALRVKEDIQTERIYNDSLKARALSFFQNGSVLTDKTLFKCKMENYHVVD
                     QETKIALERAKSFVNDVLLNHPAHFILSGKSGSGKSHLSMATAWEILERSNYDKKILF
                     ISYQELLEQIKFSYNNAELRKEIEGSLIADIKTTDLVVFDDIGAELGSGVSNSRQFTN
                     NTLNTLLEARQNKATIITTNLSGPELREAYGERIVSRIFKNSEGYALKFQQTADKRIK
                     PVKGSIA"
     gene            complement(25763..>25982)
                     /locus_tag="IXR40_001398"
     CDS             complement(25763..>25982)
                     /locus_tag="IXR40_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="phage replisome organizer"
                     /protein_id="HAQ4361256.1"
                     /translation="EERDKASIEAIEYVINWLPTNEFWFGNIRSAKKLREKFEKLKFE
                     IKADKNNHKKQSQKLQYSNPSEYDDLPI"
BASE COUNT         7004 a         5650 c         4128 g         9200 t
ORIGIN      
        1 aagctgaggt gtattaatac gcgtaaacat aataatgctt cctgtaccat cagaagtaaa
       61 atgtagcttt tcgttatccg aagttagtga cccgtggtaa ccaacgttaa aatcgctcga
      121 ttttagtttg gacattaaat tcggattccc actataatca taattcccga agtcgatgct
      181 gttactgtac atctttttca gcttgccgag gtcgccgatt tgctgattgg tttgattcat
      241 cttgtcttca actgctttaa gattgttttg tgccgatgta acgttttgag aaacggtatc
      301 aatcttagtt tgagtagctt gtagttgctc tgttacctcg tcaacagttt gatcaattgc
      361 ttgtgtggct ccctctacaa attcatttat ttgttggttt gccttttcaa tcgtagaatc
      421 cacatttgtt aatgctgcgt taacagcatc tgttgcttct tgtttgactc catcaagtaa
      481 ttgttgaaag tctgcaataa agtagtctgc tttatcttgc gctagtccgt cgattgctga
      541 acgcttcata cggaaggtga agcctaagtt atcacttgtt gatccgtctg gatactcgat
      601 gtaaacataa gcttccacca taccgttata agctttcatc gcttctggca agatatatac
      661 gacctgtcca ttcaagaagc tttcagtgat gaggtttttc gtgataaaag ggattggctc
      721 tttcgtgatc attccatcta cttcatcata gataaacatc aacaagcgca agttagctcc
      781 tagcaagtcc gccggtgtgc cgttctgttg ttcgacgttg aactctaacg ctatttgatt
      841 atcgtatgat ttaaatacaa gccccgttgc ttgcaaatcg tagtctttcg gctgtgtagg
      901 tactttgata gagccttttt tgatgacatg cgccattatt tcacaccttc aatcttagtt
      961 attttcacgt tgttgctcat tgcgggattg gaaacattgc cggatgaaat atctaaagct
     1021 ctgccgtttg acatcgttat ctttcgcgct tcgattgtca gctcaaattc gatgaacgtc
     1081 actcccgcgt ctccattcca taaattcgct tttgtaattc gcgcgtatct ttgacgtttc
     1141 acttcttcta caaagtctcc gtcaccgtct gtgtagtgga tacgaagcgt ttggtaacgg
     1201 aaagtatcat ctggcagatt gactgattgt ccttttctta attcgccttc aaaaagaaca
     1261 gaagtagtgt aaacgcgccg ccagcctaac gagttataac cctctaccgg ttcgctgtta
     1321 tgtgtcattt tgatgtaaat ttcgccgcta taacgagcaa aagcgacgat taattttctc
     1381 gaatcgtgat ccgcgaatac catcatttca acaaaactgt catcttcaat cccgtcaggg
     1441 ttgtctgcgc cccatccggc tttggttgcg tatttgccgg gcggaatgtc taaaatgttc
     1501 ggatattttt gtggtagctt ataatcgcgt aaccaacgcc cacgcgcttg cataactgtt
     1561 tccggtgtag caaagcccgc gttgctttca gtagctagga cgtgcgcgtc gtgatccgag
     1621 ccgtcgtaat ggatagccgc ttgacgcaat aaccatttca cagcctcttc ataactcatt
     1681 tcttcaaaaa tatttggttt gctttgaaaa tctaacattt aattgttcac cgccttaata
     1741 gttataagtg aagtctctcg cgcgccctac gcctttgctt gtcacttttc ttgttgctgt
     1801 gtcaacttct attttataaa acgctaattc atccggtgta tcaacttggc tagctgtatg
     1861 agagaagccg acgtcgcaaa gaatcatttt tactgttcca aacgcccctt cgacttgttc
     1921 gtgccaatgc ccgcagaaat aacctactac aacgccggcg ccttttgtat tcattgcgaa
     1981 ggtctttaat ccgccgaacg aaccgtcatt cggttgtcct aatttagacc aatcgatagt
     2041 taccggacta ccagatttaa acccttctat caacgtgcta atcatgtttt cattgcgaac
     2101 gggaaacttg ctgagaccta aaggcgtatg tcctactaac gccacatgat agtttctcgg
     2161 aacgttcact aaccattctc cgaaagcgtt aatttgtttg gcactgaaag ctcccggcgc
     2221 tgtatcgctg taaccgtcca cgtacttgtc gcctgtgccg ccttcataaa aatcacaagt
     2281 atcgaaacgg taaattgctg cgtttttatc tgggaacaac acgccaccgt acaaaccgtt
     2341 ccaatactct tcgaagtcag cgttgcataa cattcccttt cgcttgcgcc acgcggggtc
     2401 gaaacaagcg tcgtgattcc ctttgcagat aataaccggt ttttcttgtc ctgctaccgc
     2461 tgcgttagtg aagcgtttga gcgtgcctaa catggaatgt cgcgcgctcc attcatcaat
     2521 aatgcctata tcgctgccga gtgaaccaag tccgccgtcg atattgtctc cgccgtaaat
     2581 catcacatct gttttgttcc ctaatttttg aaattgaggg attgcgcgcc aatgtcttaa
     2641 ataagaagca tctttgtaac cgacgccatc tatacgcaag ttgtgattat ctgcgtgaat
     2701 gtctgtaatg aaagaaaagt taaatttgct gttattaaca ctgttgacaa ccgtattcaa
     2761 attgcgcggc actaggtcaa cgtatttcat cgtgtcgtaa tcaaaaaagc gtgttgtttc
     2821 tctaatttgt gagctgccga ctggcacttg gtatttttgg tttaaacgat cagctaatga
     2881 ttcgtagtcg cctttagctt cattcagaat gttaatgatc ataccacctg gatcgatatt
     2941 ttccagtatt tcacgattat cttctaacca ctgctcccag tcatttttgc cctgatccat
     3001 gtaatctttg aattttctta gcaaatcctc aaatgtccac acatagccag agtcacgtaa
     3061 ctggcttcta gatattccag aaatgactcg ataggtaaaa tcctgtgtgc taaattgttc
     3121 actccaagtt ccatcaccat taagtgatcg gaaactgaaa tgtgcggtgt tttcaccacc
     3181 ccattgccag tcaggctcac ttaaggtgta aacaagcctt gcttgcgctg gactgtattc
     3241 ttgtactttt tgttcaacag gttggttttc gccaaatttt gttgtattaa taaaaaacgg
     3301 cactaggccc tcgaatgttt ttagtttgcc atgttccacc acttcaacaa cgaacttttg
     3361 cgttaaaaca tccccttgcc gaattcgaac caaatttatt ccgttgtttg gttcggtggt
     3421 ggataggacc attttatgct gcgtttctgc catgactatc cctcctttag aaatcgatgt
     3481 agtctcttgc attgtggaaa tgacctgaag aagatggata aaactcatcc ataaattgaa
     3541 aatgaagatg ttctccagtg gatggtcctg ttgtccccat cagtccaatt tgctgaccag
     3601 cagttacctt ctgacctttt gagacgtcta ctcggctttg atgcgcgtat cctgtataca
     3661 ttccatcagc gtgtttaatc actgtccaat ttccatacca gtcaaagtaa tttgcatcac
     3721 ctgcaacaat cacttcgcca tccgctgaag caaaaatagg tgtattagga tttccattta
     3781 caaggtcaat accgttatga aattcttgtg ctcctgtgat tggagaagtg cgccagccaa
     3841 attcgctcgt cactgtgatt ggatccgcaa tcggcttcat atatcctttt gatacaggaa
     3901 tttccaaatc tttgaacttg tcataccatt cttgtgacca tgccgtccgt tctggatgtg
     3961 gatcacgtgg acgttcaaag ttagccacga atgcttgtgc tgctgtgttg atatcggtca
     4021 gattcatgaa ttgtgtccat gtgtaaggat aagcgctagt tgcgatccat tgaccatttg
     4081 gtgcatgcca catcaacaat ttaaactgtg ccgtgattgt gtctggatca tcactgatgc
     4141 cagcctttgt cattaaattg atcatgtaga cacgtccgct agttgcgcca gaagaatcgg
     4201 tccattgcca tacaccataa ccgaaccctg gtgcgccatt gccctcatca gcggttggat
     4261 tagcatctga ttctccttgt gcatttccaa gtaaggctgc agcagcttgt tgtgtaaaac
     4321 cggcacctat tgccgttgcc caaatttgcc aatatcgttt atcccgatca gtagttactt
     4381 ctggtgggta ttgtccgttc caaccgttat cgttccctcc ggaattgcct cctccattag
     4441 tgtcaatttt tgtaccgtta acatagagtt cttttacatc tagccgtcca tctatggtta
     4501 tatttccttc tgaaaaattg ccgtcaccat aaagattata tttgcgctta tcagcagtaa
     4561 catctgctgg aatttgaaaa ataggattcc ctcgatcgcc accgtcccca gcattaatgg
     4621 aaaaaatata gtttggctct ttccagacag caaagccgtt aatcccttta gaaccataag
     4681 tagatacaat tgagcccaag cgttctccat gtacatcatc tagtccagta gacttgactt
     4741 gtttttcaaa agaaagttct cccccctctg ccactaattg gaaatcttta tcgtcaaatg
     4801 tttttaaagc taccccttgc acgaggatac cagacagaat gcctgcgcga ataaaattag
     4861 cattgaaagt tccatccaac gtccaagcgg tcgtgctatc accattgtgt acatcttgaa
     4921 ttgtttgcca ctcacctttt ttacattgtt tgaaagatat ccctgagtta ttttggacca
     4981 taaaaaagcg tgatctagga atgttaggtc catccatata aacagtttca tagatttctc
     5041 tactatcact aacaccagct tcaattccat ttacccaata aatagaaccg ccattatctc
     5101 ctgcacctcg cataatgtca tcttgatatt ttccaatctc tgtcgattcg taaaatgtca
     5161 ttttgctaga ttctaaacta ttaatattat tgacaataga agccgtttgt tttctaacat
     5221 cttgtgttaa attatcccct agttcgatat tcgtttgacc ggtaagccga ttgaatgtag
     5281 ttttataaat acgagtttta tagtgataac ctttatcgta tctgtgaata gtcactgtat
     5341 ttcctatcac atctcctcca gtgacttcag ctttgaattg tactaacggt ctagcagaat
     5401 cgattaaggt tgaataagta tttttaagta aatctgttgg atcatctata tcatcaaaca
     5461 ctactacggt ttctcgtttt ctcattgatc catctttttg tggtatccca tacttttgag
     5521 ttgattccgg atcttcaagc caattttggc ctttaggctt atctaaagga tcaccattcg
     5581 actttttcca ttcaacatca gtgaattcaa ttcttctacc gtaaccgtca ccaacctctt
     5641 cgcctcgccc acgacctatc attgaagttg agattgagct tctatctatc tctcttacaa
     5701 ctgttaatgc tttactacca tatacgaaac gtgtattcga ttcttcgcca atttgttcat
     5761 atacttcgat ccatttatcc tttattccat cagaattcaa agaacaccta aagacaaatt
     5821 ccatacctaa ggtttgcaat tctttcaacg cttcttttac agagacatag taaaaagttg
     5881 cagttactgt tggtaacatt gcttctacgt gaccaacgcg ccaatttcct tcagtaaatt
     5941 caatcaatcg atcaagaaca ttttttaagg gctgcccact cggcctaata tctttgatga
     6001 tgtaagcatc taattcattt gtcgcaaatc ctaaccctgt aaactctaat gtttcaaatg
     6061 ggtcgctaac tttagtaatt cgatacaacg aaaaagacga ctcgttttca cgaatcgcca
     6121 tatatcttgc atcctctatt tctttatcat attttgtcgt aacgtaaaga gtatctttca
     6181 ttagatcact cttatcagaa ctaatttctt tttcttggga gacttcaatc aaacttcttg
     6241 tattttttct tttaataagt ttttgcaagt gatcaaagaa ataaactgtc tcactcaaat
     6301 tgtcgccccc ctatagaata ttttaagctt cccattattg ctagttatct tctgaccttg
     6361 cttaagataa aagttctcaa aatcactttc taaatcaatc atagaagtac aatcttctcc
     6421 gtttacagtt acctgctcat cggaaaaatc aaaaaccaac acgtctcctg tttttattgc
     6481 cgcgtcagtt atcgtgatat tttgttctcc gtttgtaatt ttgattgaat tattcatgga
     6541 taaagtaact tcaatttttc ttggtgttat aggaaactgt atcggatttc caatatagcc
     6601 atcactaaca cactctttcg tatactttag tggatccgca cagaatacat taaaactcga
     6661 aataatcgag ttggagtctc ctggaacagt atcagttgat gtatagcgac cgtagtaata
     6721 ataatctaat tcatcatgaa acctaatttc cacgtcttca ttccggtata aataattcaa
     6781 cagttctttg aatttaaact gtagtttttc tggatctcta tcttccagct tatatgttat
     6841 ttttagtgtt cttgaaggta ttttctgatt tgtaatgatt gaaccaattt gtatctcttg
     6901 ctgttcaact tctacagaaa gcatttctct accttccacc gtaagtgttt gataaccatc
     6961 aatcaaatct tctaaataca ttccatcgta catcatggca gacgtcggaa ggaatcgttt
     7021 agaactagtg agattaatgg ttgtatcttt gaatgagtac attttatttt ctcgttgatc
     7081 caaaatattc cctcctaaaa ttccagatta atatctgcac cttcgcccat agcttgtgaa
     7141 atatcgtcca taaacaatct aaacgattgt cttccaagat tgattttaaa tacagctggt
     7201 ttagtagagc cacccatatt tattttatgt tcaacttgtg caccaatgtt tttatttgca
     7261 tttttcaaat ttgcagctat atctacatca gaatttgcat tgaaaagttc cgcgataaag
     7321 tctgccatac ttccaacagt attctgtacg tcattgaatc ctcctgtcag acctttattc
     7381 agaccgttca taatagcctg accagctgga atcaatagct ttctatcgta ttggataggt
     7441 cctttgtgtt cacgaatcca atcaccaata cctccaacaa aatcttgcac agatttccat
     7501 gcattttgta acccttctag aaaactatcc atgatagctt ttccggctgc tagtaaatcg
     7561 atatttttca agttatcaaa ccagccagtt actctatcaa ccgtgtcact aacagcattt
     7621 actaaattat cccatgcctc ttgagcacca tttactaaat tgttgaaagt atctatagta
     7681 ccttgtttta ggttttccca tccctgaatg atgttatctt tggttccagt aattaaatca
     7741 ccaatccaag atttgaatga agtccaaatg tctttagcac cttgaactgt attgttgaat
     7801 aaatctatcg ttccttgctt taagctgttc caacttttta taagagtttg cacgatatta
     7861 ttaaccgttt ggaaaaacca ttgttttaga ttattccaaa gttcaattgc accatatttt
     7921 gtatcaatcc aagtttgaat tatggagaat tttagattta tccacatttg aattgcactg
     7981 tatttaatat caatccataa attagtaaaa aatagtttca aatcaatcca aatcatagtc
     8041 gcttgataaa ctacttcatt ccaaatatta gaaatacttt gtatgaatcc agtccataaa
     8101 ctaacggcac tatttactat tgcaccgata tattccgtaa atatattttt tacagatgtc
     8161 caaatattta ccactgattg gacaagtgtg ttccagatta gatctaaatc ctctttcatt
     8221 tgttcgaagt caccagtaat taaatctata ataaacagta gtggcgcagc tattaaagac
     8281 ttaatgattt cccaagcatt tactattatg tttttaacct cagcaaatat acttgttatt
     8341 gctttcacta tattagagaa cacatctgaa aagctactta caaatggacc aatatatttt
     8401 agtataaaat caaaaccaga tttgatttta cttgtaattg ttttccatgc agtagatata
     8461 gtatttttaa acccttccca tttttcacca gcacttgaaa ctaaatcatc aataactgat
     8521 atgacacctt cttttaaact attccaaatc tctgaagcag agtttgcaat acttgaccat
     8581 aaatttgaaa agaactcttt tgttccagtc catttgtttt taatccaatc tgccgctttc
     8641 ccaggggctt cttgaactgt agtccaaaca ttgtctgcgc cttctttaat ggacttccat
     8701 aaattgttaa accattctcc tgtagatttc catgcattct gaatccattc tactgccgag
     8761 cttacagcag acttgattcc ctcccataag ccaatccaaa agtttctaaa atcttcactc
     8821 gtattccaaa gatagatgaa acctacaacg agtagtgcta ccgcagctat aaccagaaaa
     8881 accggatttg taagaagacc cattgcttta cttaatccac taaacaattt tgaactttca
     8941 cttaaagctt taaaagctac tttcacccta ttgatccata taattactga accaatcata
     9001 aaaattaacg gtcctatagc agcgacaatt gctcctatgg ccactactaa tttttgagtt
     9061 gattctggag cacttacaaa tttttctact aagccggata tggcatctgc tacttttttg
     9121 atggatggtg ctagaatctt ttgaattaca atagctgctg actcaaaagc tccaaacatt
     9181 tgctcgatgg aagaattcat attatcttgc atggtccgag ccatatcgtc agctgcacca
     9241 tcagaatctt tcagagattt tgttaatttg cccaatgaat caggtccttt atcaatcaaa
     9301 gccatcatcc ctgataatga ttcttgccca tatagtgtta ctaaagcatt ttgttgttgt
     9361 tcaggcgtca ggccttcaaa agctttttta agtaattcta cttgagtttt taaaggtttc
     9421 attttaccgt cagcatcata aaacgaaaca cctaaattat ccattgtatc ttgcatagcc
     9481 tttgttggcc ttgctaacct agacaatgct cctcgcaacg ttgtacctgc ttgagaaccc
     9541 ttaatgcctg cgtcactcat aataccaata gctgctgcag tttcttccaa agaaatcccc
     9601 attgaattag ctacaggagc aacatacttc aatgcttctc ccatgtctcc aacttcagca
     9661 ttggtatccg cagcagcacg agcaaataca tcagcgacat gtcctgcttc acttgcttct
     9721 aaaccaaatc ctctcaaagc agtagcagta ttttcagaag ctagagccac atcccctcca
     9781 gatacagctg ctaagtctaa aagacccggc attgctttca tgatttcttg tgcgctaaat
     9841 ccagcagaag ctaagttttc cattccagca gctgattctt ttgcgctaaa agcagttttt
     9901 gctcctagat caatcgcttg ctgtttcatc tgttcgaatg tgtcgccggt tgctcctgat
     9961 atagctttta cacgactcat ttgtgcttcg aagtcgccac caactttagc agctgctacg
    10021 cctactccta taagaggagt ggtaatatac tttgtcattg cggcaccagt accttgcatc
    10081 actttaccaa cagcggttgt catactattt gaattctttt caaaagtttt aacagcatct
    10141 tgtgcatctt taaaagtctt tacaaatcca ctatctgtgg cttttaataa ggcttcaaca
    10201 gaaaattgtt ccatgattct cctcctttcc tcaagagtta gctttagtta gtaagctttg
    10261 gaatttttta tcttgttttg aaagttcgga aactcccatg attgaatctt cgattttttg
    10321 ataattgaag aattcttcaa aggatcgata tacaggaact gtctttttgc ctactttttt
    10381 ctccgcttgg acttgctgat ttgcccacgc taattcgtga atcaactttt ctttgtcaag
    10441 ccaagataac tgggctgcag tcatacgaat gttgtattca tataacgtca ttctttcgat
    10501 atctgagata ttggtcattc ccaaatatcg aaaagaattg ataagaattt gttcgtatgc
    10561 cagtgcagaa tctattccac ttgttgtttt tccgcttctt tcaatttctg attcaggttt
    10621 cggaccgcta actttcccgc gttcgactcc gccaattctt ttaggacttc atcaaacaat
    10681 ttttcaatgt ctttaacttc atcgatgtaa tcatccaatt catctaatgt aatagattca
    10741 tcttcagttc tatttgctat ttccagaact cgtgataacg tgttaacgtt ataagaacgt
    10801 agctctggta agacttttgc ggagagtccc attccaaatt ccatatttcc atcgacgaaa
    10861 ggcatcactt tatctaattc acgtacaaat ttagtgccaa atttaaacga atattcttta
    10921 cctttaattt ttaatttcaa tgtttttcat cctcctaaaa taaaaaagag agcatctaag
    10981 ccctcttatg ctcctgtcga agttgctttc acggtatctt tgaatgcata ttgaacaaca
    11041 tcggcttgat cttctgtcaa ggttgcataa ccatcttgac caacaccatt tactgcaaat
    11101 gataaactta attcaacgtt atcctctgca gcagccgatg gagtaaattc agacacatat
    11161 gcttggtaat aagtagcttt gtacttattt gcattatcat ctgttccctg ttctgcttta
    11221 ttaatttccc aaatttcaat gatatcccca tttaataaag cttgtttcat ttcatctaca
    11281 tgagaatctc ctttagcaac tattgaagta gccgaaaaat catattcaac cgggcttaaa
    11341 ctttgaacgt ttccatcttt tgtcactgta gagtctgaat ctcttgataa accattttcg
    11401 tgttctgttt gaaatgccat tttccaagcg gcttcctgag tttctttttt caataagcga
    11461 taaagcaaaa tgacatcaat accttttaat gcttccatgt tcttcctcct atctaattct
    11521 aaattcaagt gtgacaaccg cccgttttag cggtgtattc gttgttgtgt cgtccatcac
    11581 ttgaattcca cttgcttgat aatttaaagc ccaataatag ccttctgtgg cttctatcaa
    11641 tctagcttca ttaaaaagag cagatgccat atctgacaac tgctttcgtt tcttctgtaa
    11701 tccccaaacg gataaaacca caatcacaga ccctttaatg tcagttttat ttacttcatg
    11761 gattgtctga gtgttctcaa attccacaaa aggataacca acatcctcta aagttttgta
    11821 atcgtatgtt ttatatccaa gtttgttttg ggatatttta aaaagttcat caaaaattga
    11881 ttgatctctt gtcttaatca tcatttcacc aaggctttca tttcagccat aaatttgact
    11941 ttttggtaat taaacgctgg tctaacataa ggctgtgccg acataaatcg agtgccatat
    12001 tctacataag gtgcataatc tgctgtcggt cctacaatac cagttaaacc agcttctaaa
    12061 agattcatgt ttattgatct tcgtaagtaa cctgtatcca ctggcgcacc tttttgcatt
    12121 cgttcagtca tttcagcagt attacttttc acgacttttt gaacgtcatt aagcgttgct
    12181 gcttttttca gatgtcgcat cagctgatcg attcctttat attcaagttg tgccttcatc
    12241 aagaaccacc tcttgcacaa ttaaactatt tctatatgct ggatttctag ctgttttttg
    12301 ttgccaagtc tttccttcaa tctcgatata gtcaaatgta gggatagaaa aaagaggctg
    12361 cgtcctaatg accttcgccc cttcttccac actaccaaaa atagtcacac ttctatcagt
    12421 gccaatatct gtcacgtttg cctctgttct tgttctttct ggtttgcctt caacccactc
    12481 accgagatct ggatcatatt tagagtcaga tgaacgttta acaaatataa tttcatctgt
    12541 aaatctcata caaatttaaa cctccctcgc tttggcttgt acaactcttc ctgatcttta
    12601 cgcttaaatt catcaatctc attttgatac tctgaaaaat ccgagtcagg aaaagccata
    12661 gataaacctt cttgagaata tgactgcata ccttcttgac caattctatt gaatcttttc
    12721 aacgatactt catatacaac tgtttcaaat tctttaggaa cttcttgcgt atttaacaag
    12781 gttttcatac gctcattcgt tcttcgctca ataacttcaa gcttttcatc tattgttcct
    12841 ttaagaagtt ttttaatatc atctgcaatc atcatatttt tacttcctaa ctagcaggtt
    12901 gacctgtcac attgattgaa gtagtgaatt ctccagaagt aaatgtgaat gttgctgacc
    12961 cttctgctgc aatcgttcca tcaaaaccac cattttcatt tttggtcact gttgcgatag
    13021 ctccatcact tgaagttgct gtagtagctg caacaacagc agctgcatcg ctagcatctg
    13081 caggcacagc tgaaatagta aatgttttag tatcgcctac tttaccggtc catgtctttt
    13141 gatttggcac aataccggta gcaggcgtta cgcttttggg gaaatcttcc caaatgcttc
    13201 atcttttaca atcataaatc caacatccat tgttgcacgc aaagcaatca gttcttgctc
    13261 aaacaagtta actggggttc catcttcatt agttaaagta gacaattggg cttcttcaga
    13321 aatcttaaat gaaatattat atgggatccc ataaaacatg taattaaagt ctccagcgta
    13381 aagtgttcct ttatctaaag acttaaggtc tactactggt aatccgtcaa ttgtattagt
    13441 agagcgatca taaataaact caacatttga cccgactgtt tgagctgcag aacgtaattc
    13501 tgtacgattt tttcggtttg aaataaacgc attaggttcg aattcatttt ctgctaactt
    13561 gtcttctaag gctaggatat tatcataagt caatccgcct tcaaccacat tccccgcact
    13621 aataactgat ccgtctagtg actgaggaaa tgggttttct ttatttaata aggcagctgc
    13681 atcaaatttt ttatagaaag cttcagcaat ttttggctgc atctcctcaa agaaatctga
    13741 taatttataa tttaaatatt cacgagaaac cggaagaatg acaccgagtt tttttgcagt
    13801 catcgtagct tgcatccatt taggtttaga cgttttaatt ttttcacctt cacccaccca
    13861 gtatgcgcct ggtccttctg caaagtattc aaatttcttt tctttgtcag tcatttcttc
    13921 gtattttgct aactgcatga tcttagaatt ttccataact tcactcaaaa tgagcgtatt
    13981 atatttatca ggaatttttc cctctttcgt ttcatatacc aagacattat ctggatccca
    14041 tgtttgagca aacatttgca agttcattgg taaaagttgt ttctttttca ttaagttttc
    14101 ctcctatttg ataattcgat ttttagcagc tagtttagcc actgtttctt tagtattttt
    14161 cgatgctgta aattgtccac cttcatttgg tggtgtttgt cttgcgtttt ctctcttaat
    14221 caaagaagca aagttagtga tgactgctac agcttgtttt gtggcatctg catcatcaga
    14281 aacaatcaga ccaagtaaat catcatcgtg tggtaaattt gcatctgtca gcattttaga
    14341 agcttctttc gtcatttcag atagtgcctg tccacgcttt aattcagcga tttcagcttc
    14401 tttttgctcc aactcatgct gtagtttttc ttccgcattc atttttgcca gctttttagc
    14461 ttcttctttt tttgctgcta gttctttttc ccacgctgct tttgctttat tcgtctcagc
    14521 agcgatcatt ttcgctactt catcacgaga aaatgttttg ccagtattgt tttcttcttt
    14581 tgcttcgggc ggtgtctctt gtgagccagc tggtaggttt ccttgttgtc cctcatcacc
    14641 agatccacca tctcctggtt cagaaaaaaa ttgtaagttc attggcataa ataaacgttt
    14701 tttcatgatt aatcctccac ggttacgccg ctacccgata aatttgacca gttacgccgg
    14761 tcagccgaaa atagctttct ctttaacgcc tgtaagctgt aagaaggcac aataaaaagc
    14821 cgttaatttg tgttaacggc ttgatattcg ttctatataa ggtgctgtac tgcatcgaca
    14881 aaatggatgc atattaggag cgttacttcc tggctgcata tcggcaacat caaaaacttg
    14941 attatttaac ggtatacata gtttgcacgc cgttggttct gctatataga tgtactgggt
    15001 aatgcctgca tctctataac ttcgttcttg aatccctacc tgaactctag tcgtttcagt
    15061 caccatcaaa cgttgagtgt tgaacttagt gttttctcgt ccttcagctg ttaaatattc
    15121 tgccaattta gatgcaagtt gcttgggatt tttccccatc gttatacttc tgactaacaa
    15181 cctatctaat tctgatttca attcagattg atacatccat aagcgatcac taaaagacac
    15241 gtcatcactc aaaaaggagc tgtttattac tagttctatc agctttgcat atccacttga
    15301 agcaatagtc atttctaaaa taccggcttg tctcttcaat tcagctaaac cagcttttgt
    15361 taattcattc gaaaagtact tatccaattc attaaacagt gaaatcaatt caagcccgat
    15421 attagctttt aagagctcta atctatttac acgcatcgta agattgtata gctttaattc
    15481 ttggtttgct gtaggagaaa aatctttctc tttgacatac ttctttgctt tgcgagcgaa
    15541 tgctttgaca tccatttcac tagcacgctt catcgcttcg ctacgagtga ttttctggcc
    15601 attggagaaa ctgtcccact gcgcgtctat ttctttttgt atcgcatctt gtgcgtattg
    15661 catgcgactt ttaatttctg ccatgcgctt tttatcatct ttaatttgtt gcttttgcca
    15721 ttccttttcc cgtttgatcc aatattcttg ggagttcatt taatcacccc cctgtttcat
    15781 cttttttgtt gttaattact tcttcaccat ctgaatcaaa aatgccaatc tgcttttgcg
    15841 tttctttatt tactcgtttc aactctgcct gtacatctgg aacaaaagaa gcgagtccta
    15901 agatcgtctc ttgactgagt tcagctccag catcaaccaa agatttcaac tcttccagaa
    15961 tggctttagg tagattaggc gtaaatatta cacgtaagcc tttcaaatcg gagttatcca
    16021 tttcagaaat acttgatttt aggctaaata aaagacgata acgccgcata aggccttttt
    16081 tgaatagcct ttgctttgtt gccgtcattt gttcaaatcc aaataattta tatttcattg
    16141 cttctcccga ttgcactccg gaaaaattgt catcagtaag atcaggaacc atggatattt
    16201 cgtgaatatc cttgcgtact ctgtatttgt atgcttctac accgttcaca tcatattgtt
    16261 tgtaaatata tcctgcagtc acacttgttt tattaccgtt cacatcagtt ccagactcaa
    16321 gcaaaagcat attcgcttct ttctgcttga tggcgtcctc tgtggatagt cctgctgctt
    16381 caatatcacc actaataact agaagagcat cgtttagatc agtcatataa ttggcggtat
    16441 cagactgccc tgcatcgtat agatcaatca aagatagtac atcttcatac aagcccatcc
    16501 gaaaacgatt aggagaatac tctgtaatag gtacctcttt atattcatgc ggttcatcct
    16561 ggggattctt taactcaatt gctgttagtg tcgtctcatc ataagtgata cttttttctt
    16621 ttgtgtatac gattggttga atgtactgtt tatcagcatc cttgttgaat cttgtcttag
    16681 gataccgtac agccaaaata ggctctcgtt ttactgtagt atcatataca acaaacgttt
    16741 caaatacatt agccaaatca acataatctg tatcatctga atctcgatag ataatctcat
    16801 aggctctccc atacttatcc atatcaagcc agagttcagc atttaaccca tctatgtcat
    16861 tattagtatt aaactcttcg atttcttttt gttgatttgt gtcctcgatt tgcactttta
    16921 taggattgcc tgtgttgtac ccaacatcaa acgtacaaag aacttttcca aagttatgtg
    16981 ctgatcggtg atccgctttt tctttttctc tgcgcctacg gttatccatg atatttgtat
    17041 ttctagcttt ataataatca tctaatacac ttagcctttt tacctgatat tcatgatgat
    17101 gttttatcat tgctgctaaa gtatctaaat cgttaagtaa atcttctgct gagctaaatc
    17161 tatagtgaag atttgagtct acgctaaact ttacataatt tgtgttcacg tcattagaat
    17221 aatgtatatc agctccgtat tcaaactcgt ttaccttatc catttttcac actccttaaa
    17281 acatgcgttt aatacgttta atcttttcgt tgacattaac ttttggtttc ttaagaagct
    17341 catgagtata tatcgcatat cgaacggagt ctagcacatc atcatattct tttattggct
    17401 cgcctttttt cttgtcccaa atgtattgat aaatttcatc ccgaaatttc atcactctat
    17461 cttgacagat aaacaattta tcttgtttaa atctcttggc gacttcctca actccagata
    17521 accgtgcttt atgagcattt ttagcattaa tcttttctct tacaaaccta gccacatgct
    17581 ccggtctcgc agagtcacaa taaaaaggta ctcgtaagcc gtaacgctct tgaatgcctt
    17641 ttgccacatc tacccaataa tcaatctctt caaattgagt agcatgttct tcgattaaat
    17701 aagctgttcc gtcatccgtt tcacctataa ctacgattga accccagtgt tcatatcccc
    17761 agtcaacacc acaataaaag ttgctcaaag gtggtaagtc ttttgactgg atgtagtgct
    17821 tgctagcatc aaaatcacga taaacgacac cttctgcaga aacccataaa cctttgatat
    17881 cacgatcata aaacatgccg cttggtgttg attctttaat attgttacga tatcgttcag
    17941 ataaaaatgt attatcatct aattcaaagt ggaacgattg aatatttttg cttgaattgt
    18001 cgatatactc tttctttagc cagtgttccg ggttgtcagg gtttgtatca gctagtattc
    18061 tcgctcctgt tcctgaacaa cgtgaaacga tttcagcaaa tacttcttgt ctagctagcg
    18121 atgcctcatt gatataagcg ccatatgctg tcataccacg aattgcgcca acaccgccaa
    18181 tgtttcctgt ataagcttgt acgaccttaa cgccaaatag cttaaagttt ccatgtttat
    18241 cgaatttagg ttctatgctg tacatgttgt atagttcctg taagatgttc ttttggattg
    18301 ttgcacttga aactcctgct aggatataca ttggttcctt aatgtcttct tcatcggcaa
    18361 tctttcgcac acgtcgcaat tcaaacaaga acaaatcatt gtttattttt gtttttccag
    18421 aacgttttgc tccatgtaat aaagtaataa accaatcatt cttaatggtt ttatttaaca
    18481 cgtcgatttg ctttgggtta taaatatcaa ctagtgccat ctaattcacc actaatcttt
    18541 tctaacaact catcaagttt ttcttcggta gaacgctctg agtttatctg taattgttct
    18601 aattttgctt gcattaattt tatttctgtt tgagcttttt ctaattgcgt ttgtgataac
    18661 agcgatttat acttcaaata caaatccaag gctttcaatt tgctttctaa atctggtgta
    18721 tattcatatt gcatatgttt aataaccttg tttttctcca agcggtctat ttgcttgctc
    18781 acgcttattt gtacttctcc ttgccaaata tctatcaatt catttaaagc gtcctcggca
    18841 cttaatttgc gcttcttttc gataggattt agccgttcat taatatactg tattatgtta
    18901 ggtttagtta ggttttcctt acctattact cttgctgatc gtttgctata acctgcttta
    18961 atggcggctt gagtagcatt accaccattt tttatatatt catccgcaaa agctttttgt
    19021 tttggtgtca aatttaccac attcaagcca ccacctttca attttattaa caatatctct
    19081 caatatttgt ctgtatgttc tgctcactaa aatatccatg gccgcagtaa cgaagattgt
    19141 acttatcaat ctcttttggc gtagcttctc tggtcatttc aatgatggag tacttctttt
    19201 taatctggac tgactggaca actctaattg gatcatctgc gtttggttgc ggatatttat
    19261 ttgataatga tacataccag tagttcctca ttacgtatca ctctttctgt tggttactgg
    19321 cagaaaaggt tcgcatcata aattccatag cctgtgcgtc attaaatcct tgcagaataa
    19381 gctgatcgta gaaatactta gcttgttttg cgattaacgc taagcttttt tgagtttcgt
    19441 agaatgtcgc ctccattgtt ttgtttgctt cattcgtttt aaacaactct cttaattggt
    19501 tttcgttcat ttttttactc cccttccaaa ataaaaagac cactcgatga gtgatctaat
    19561 atgtaaaaac tacacctcat aaacgagatg cagttatagt tctatcaagc aacctacacc
    19621 gattccatcg attactatcg acctcgcctt gctcgtgtac tttgagcgcc catttccaac
    19681 cctcagttgc caaagtcact ggcaaggaat cgaaccttgc atggttgccg aagcattgac
    19741 ctaacacaca tgcttagcgt ctaccctttc cgccacagtg acaaattaat attgtgaaaa
    19801 taaatactaa gtgtataatt ttatttatca gcgagtggtc cgctgaaata aattaaaagg
    19861 tggtgaaaaa tttgtacttt gttataagag aagcaactaa tggccaatat tacttcgtta
    19921 ttaagtccga taacaatgaa gtagtagcaa ctagcgaaac atacttgact aaatattccg
    19981 ctgaacaaac cattaattct ataaaaaacg gaatcaccaa agactctcaa gttatcgatg
    20041 tgactaaata agacgactaa cttcatttgc tagggagttc atttcagctg ctttttctac
    20101 caaagcagtt gagatacttt ctagcttttc tgatttaaca gaattaaata ctggcgtctt
    20161 gatactaatc gatacatctt gacgaggatc aggactcgtt gctctatttt tttgcaccac
    20221 tgatctgtac ttttctactg aatgatactc aattacttgt tctaaatgtt ttttgtactc
    20281 tttacataca gcttcttttt ggatcaattc taaacgttgt tgctcaataa tatcaatcaa
    20341 ccgttcccga tccatacctt gatactttat ttgctcgact tccattcgtt ttccctccaa
    20401 tacataaatt aataaacagc aacggatgat agataataag aacaatttag aaggagttgg
    20461 aattcacatc cttattctta atatttccgt tgctgtctat cgaagcttaa ttgtgaaaca
    20521 ataataaaac gatgttcctt ttattattat tttgtctcag acctatcact aatctttcga
    20581 cactatcata ataaatcatt taccaggtaa gtgattggta taaaaaaggt ataaaatgga
    20641 aaccaaatgg gtaatcaaag ggtataaaaa gtgtaaaaac tggctactta aaagcaacca
    20701 gttctaacga tgaagcaaat tggatgataa ttctgtttga ttctacttta accgattctt
    20761 cgctagtatt attcctttga gcagttacat aaatgggcag accattgata taacgatcat
    20821 agaatatctt cttgcgcctt tctgttacat caggtttatg cggatgctga attgctgaat
    20881 agccacgaac aaataatttg tgcaagtact caaattcttc ttgcgcttcc tctctctcaa
    20941 tcatcattcg ttctgcttca aatgtattat ttgctgtaga aggtggaacc aaggagtaag
    21001 atgccgttac tttaggctcc cgaggttgac ctatcctaca tctagctgac agatatgctg
    21061 aaagaaaaac accaacatta tgttttgtgc gatccatatc cacatctttt gcctctggtg
    21121 tctcatactt ctttacatcg aaaagtacca tccattgatt cctccattta tgatataata
    21181 attgtgtcag aattattaat taaggtcgga ggaatccggc tttttttata cccatgctta
    21241 tgctaagctt ttcaagtagc gaggttgcac tcgttaccca tatacatgtt gagctatctg
    21301 gcggaaaaca gatggctcac tatttcaata ttctgctaag gacagccagt ggtcggctgt
    21361 cttttttata ttttaatgag aagccttact tattttttta tctttattac gaaaaatgat
    21421 attatctatt gataataaag cgtataggag atggttgagt gactatgtgg agcatgctgt
    21481 tattttggat tcccgtttgt attggtatcg tcgcattttg ttactttgtc aaacactcta
    21541 gaacaaataa gctcctcatg ttatcttttt tacctatagt attttttatt gtacaaattg
    21601 ttaaatatac ctatattgaa tcgcaagaaa tattcatttt ttatgtggta ggtttattta
    21661 tctctgtggt ctttttcata atgatacttt cctattttta taaaaaataa atttttctct
    21721 tagaagtaca ttttttcgct gtttatatag ccttcatatc caccaatctc gctacagcta
    21781 aattctcttt gcttttcgct aaccacttat cacattccat cgtgttttca atacgaatga
    21841 tcgctgagtg attatagacg tgttctacat atccacgaaa tggatagatg aacccttctg
    21901 cttcgcagcg aaccatgtca ccgactttga attttggttt cttacgtttt ttaggattct
    21961 ttgtcggcat atctagcatt aaaccgccga taccatgact actagcgtaa aatccgtctt
    22021 ttaatttcat ctttctacct cctcatgatc gacagtgacc agttcatata cttgtgttaa
    22081 tccaccaagt cgtcgtgaaa cttggttagc ttcttcgagg ctatcaaacc atctcgcact
    22141 ttggagtatg tctacaatga ataatgtgtt agcccctata gagcgttcat cacttctata
    22201 aaatttattc ccgaacttta ctacataaat cttcattctg cttcctcctc aatcgtccaa
    22261 gcatttgtaa atttctctaa gcttattagt tcatcttcat ttaaatatcc gtaaccatat
    22321 aaggattcta aaaggtcttc ttttgaatag cctctaaaat caagtctgag accgcttagg
    22381 atgtatacat aggttttatt tccataaaac ttgattgtgt atgctttcat cccacttcct
    22441 cctcatcgat ctctatctcg acatctctgc cttctaaaat ctgtttggta tcaatatagg
    22501 ctacgagtat ttttcgattt tggcttaaag caatatacgg atcaatcaaa gcaacttctg
    22561 cgtgtagacg ataataagca atacaatcta tttctaaaaa tatcaaacga tcaatagcat
    22621 cattaatcat aaaatctgta acgttttctg ctgtatttaa accatctgca tatttaggca
    22681 ggacttcatt attgatgaac tcagctacat gttttggaca taaatcagtc agttcttgtt
    22741 gtgtatagtt catttgctgt cctcctgatt aatatatttc ctcaaactac gtatcccttt
    22801 accacgtttt tttgttttgc gctcaatcca cgttcctgta gttccccagt agtcaataat
    22861 tccattatgg gtattaattg caaattgatg attgtttgga taatgagtaa attcaaatcc
    22921 caaggtttca atatttttag ttgctgaatt gcccatcttt ctgacatgtt gttttctacg
    22981 ttcttttaga tgcggtttaa tatctttcca gtattcgccc atatcgccca tttcgctgtc
    23041 ctcctatctc cttgtccaca ataaaaacca catcaactct tctgtcgtac cgtttaaata
    23101 aagatttatt tctgcaccaa tcgcaactaa aattccgaca acaaacaaaa taatccctac
    23161 tgctgtatat tttttgcctt ttgcactctc gtaaatgagg tatgctccta acatcgctag
    23221 taagccgcca attacacacc aaaatattgt taggctgatc atttgctgtc ctccaaatca
    23281 ctcgacttca cgaatacacc atctaccatt tttcctgtgc gtcctttgat ttcgttgtat
    23341 gcttggttca gacactcgta caaatccata tcattttgca tagctaaaat aatcaaggtt
    23401 actactacat ctccaattcc gtctcttaaa ccatgttcat cttttctagc tagagaagcg
    23461 gcaacttccc cgatctcttc gatcgttttt aacatttgct tgctggaatc agcttgatcc
    23521 aatcccttat ctttagccca ctgctctact tttgtgatta gttcgtccat tattcattct
    23581 cctttatata tttaagttgg ataatacaac ttgtaacaaa tgaagctaat gttaaaattg
    23641 tgccgattgg tgttaaaaaa ccgcttttta tcgcattaat taatatagct acaaatatcg
    23701 ttatatagaa taaaaagtga attgacgcta acgttgaatt aaacatctag tcctcctcga
    23761 aatactcatt cagtatctct ctatactttt ctacaaattt gaaacgatcc tgatgaagtt
    23821 tcttgctcca atttgtttgc cgatccagct cacgcatctg atcgaaccct ttttgaattt
    23881 cgttgtaata aaattcaatg tttgctgctg ctttccaatg cctgctactt cgcactcctg
    23941 ctcctgtttc agccatttcc aacttaacta attccgctcg ttcttttgct tttttatctt
    24001 tctgaatctt catcatgatt ttcttgagga tgatatcact gtattgtgta atgagatcca
    24061 ttatttctcc tccacatacc taaactgtcg cccctttgaa tcaatccata agctcctagc
    24121 tctatcccag atgatgtttt tgctcagtcc agtaatttca gataactgtt cagctgtacc
    24181 cgttactaga attcgatcac catgccagat tgcaattttt ctcggcgttt tccgtttagg
    24241 cttttcagtc cacattgatt taccgagctt ttggacttct gcaactattt ctttgtcttc
    24301 ttgccaattc tcagaatgtg tcagttcaat gattcgtttc attgctgctt tcttacccac
    24361 gctcattcct ccaatctacg aatttccctt cttaaattca ctatgtgcaa attgattgcc
    24421 tttctcgccg tttcattgac catcactgcc tttatccgtt ccagatcgtc aatctcacgt
    24481 tgaaggcttc gaatacgcat ttgaatcact tcttctgttg tcatgatgga ccacctcgtt
    24541 aaaaacgctc ttccttgaac gtattccgat attttttagc taatatcaac ggcacttgat
    24601 attgatgaca gaacaacttt gccttgatct taaagtcttt tgtctgcatt cctttgacat
    24661 ctacgacttt gacaagtttg ccgtttttat aaaatgtgaa gtcgggaata tactcgatct
    24721 tgcgatactt ttttccatct agttcaaatt tcggcatcag ctcaaatctt tcctgaagtt
    24781 ttactttcca gccgttcgct tctgcttgcc acaaggctaa atcgtaatac tctgcttccg
    24841 cgatagaatc aaacttgata cctcgatgaa cagttttctt attacggtat ttattcatgc
    24901 gatactacct ttcactggtt ttatgcgctt gtctgctgtt tgttggaatt tcagcgcata
    24961 accttctgaa ttcttaaata ttctagaaac aattctttcg ccgtaggctt ctcttagttc
    25021 aggaccggat aagtttgttg tgatgatcgt tgccttgttc tgtctggctt ctaagagcgt
    25081 gtttaacgtg ttgtttgtaa actgcctact atttgatacc ccgctaccta attcagctcc
    25141 aatatcgtca aaaaccacca aatcagttgt tttgatatcg gctataagcg atccttcaat
    25201 ttcttttctc agttcagcat tgttataaga aaactttatt tgctctaata actcttgata
    25261 gcttataaaa agtattttct tgtcataatt tgagcgctca agtatttccc aagctgtcgc
    25321 cattgacaag tggctttttc cgcttcctga tttccctgat agaatgaaat gtgcaggatg
    25381 gttcagtaag acatcattta caaagctttt agctctttct aaagcaattt tcgtttcttg
    25441 gtccactacg tgataattct ccattttgca tttaaacaaa gttttatctg ttaataccga
    25501 accattttga aaaaaactca acgctcgtgc ttttaagctg tcgttatata tccgttcggt
    25561 ctgtatatcc tctttcacac gtaacgcttt ataaccacaa ctcatgcatg ttggtttaca
    25621 acgttctgaa ccatccttat ttttagctcg ccaactatac aaaggttcgc tacattctgg
    25681 acatttcccg ctttgcacta atactcttct tattagtttc tccatagcat ttgctaggct
    25741 ttccatgtga tgcatctcct ttttaaattg gcaagtcgtc atattcacta ggattgctgt
    25801 actgtagttt ttgactttgc tttttatgat tattcttgtc tgctttgatt tcgaatttga
    25861 gcttctcaaa tttttctctc aatttcttag cacttctaat atttccaaac caaaattcat
    25921 ttgtaggtag ccaattgatc acatactcaa tcgcttctat agacgcttta tctctttctt
    25981 cc
//
LOCUS       DACGEU010000036        25359 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.036, whole genome shotgun sequence.
ACCESSION   DACGEU010000036 DACGEU010000000
VERSION     DACGEU010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25359)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25359)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25359
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.036"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            57..251
                     /locus_tag="IXR40_001399"
     CDS             57..251
                     /locus_tag="IXR40_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361257.1"
                     /translation="MYKLNEIVPVQLGNEKSAPEKGKPAAAKLAMRIKRENGSEVLIY
                     NGINNYILQAILKELLSNAL"
     gene            241..594
                     /gene="tnpB"
                     /locus_tag="IXR40_001400"
     CDS             241..594
                     /gene="tnpB"
                     /locus_tag="IXR40_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HAQ4361258.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
     gene            696..2243
                     /locus_tag="IXR40_001401"
     CDS             696..2243
                     /locus_tag="IXR40_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HAQ4361259.1"
                     /translation="METTDTLLQLLQEAHKTNQAQQQTIQNLTTEIQLLNEKVNYLTN
                     KLFGRSKETLFEETNGQLNLFSDEEISVSVPEAAATIIPVKGHQRVVGTKADKIKHLP
                     ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCLTHYQHTYCCKSCEK
                     EGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQENYWKQTHGLDISRD
                     NITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESAKTDTYYWQFCTGKD
                     SQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESVRLVYCFAHVRRKFF
                     EAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQQELRPLFIAFYEWM
                     ATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERNIKELVIGRKNWLHS
                     TSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLSAETLDQLLPWNKDV
                     QQHFSRN"
     gene            complement(2316..4889)
                     /locus_tag="IXR40_001402"
     CDS             complement(2316..4889)
                     /locus_tag="IXR40_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361260.1"
                     /translation="MNQYVKKLIASILFVFPLLMVTSVFADVEKTSESTQSENQSFDK
                     TTFSEESITSETTESQSEAPTSNTRQEENKTSETSEVAEQTSDSSEEVQVRVVSADGY
                     SEAATTEELTQLLADESVAKIRLTQPLTLDRELEIKRDIVIDFGGLAHNFGTHHIYIN
                     ETPQSIEFQNFKGTAAHPGGLIPNIDGNAIIIAYMSDFWGNRYHFTGEIKFTGTLDLY
                     DGSKLGLIYAPRATVTLDGVSGVLDVQPVKEGMNAAPGKAYFCRSYQLNVINGSQLYG
                     PYLGKFYGFLDSGDETGSGKTAPGLHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVT
                     FKVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSRVAVSNDGKITINTATTGGFRLQG
                     DSSQIHVSSGGQISVKMAGDGDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSA
                     VRFENGTQKLTVTNGGSLKVRNAGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFT
                     VTGEKSNIDIRADSGATVDTTGDIDLNFMAGEKTYLVMVGKTGEDKTGIISGDVLNVD
                     LESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKAGVTFDNFEKDP
                     DYFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRV
                     PTNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSPVEITALTQGQTDE
                     NEGTGYNPWGEGEQGGLFEVQVPNEERLTTGDQVQIVAAKKVRGGQEVTELDSAKTTV
                     DVIPPEPAKLSTTLINAASRSITGTGEAGALVSLKKNQAVLSETTIDDTGKFVLSIPE
                     K"
     gene            complement(5111..5995)
                     /locus_tag="IXR40_001403"
     CDS             complement(5111..5995)
                     /locus_tag="IXR40_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HAQ4361261.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPEAINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSILLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            complement(6090..6527)
                     /locus_tag="IXR40_001404"
     CDS             complement(6090..6527)
                     /locus_tag="IXR40_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361262.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWVFYLVKK"
     gene            complement(6744..7655)
                     /locus_tag="IXR40_001405"
     CDS             complement(6744..7655)
                     /locus_tag="IXR40_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAQ4361263.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
     gene            complement(8032..8670)
                     /locus_tag="IXR40_001406"
     CDS             complement(8032..8670)
                     /locus_tag="IXR40_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4361264.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDFVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFNQETKHLTGREKRLIKRNALSFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKEQVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            complement(8674..9444)
                     /locus_tag="IXR40_001407"
     CDS             complement(8674..9444)
                     /locus_tag="IXR40_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HAQ4361265.1"
                     /translation="MIDVSGRLIQITEKETHPVILIPERYRHTDLKNDLAQITEYYQE
                     ISEKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSTYWERNILSGEIYPPLK
                     IKIGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLSRSFHYLIQIFLLTFFS
                     FFLLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNLIKWGTTSVIFLFLIER
                     EPKYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            complement(9862..10278)
                     /locus_tag="IXR40_001408"
     CDS             complement(9862..10278)
                     /locus_tag="IXR40_001408"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361266.1"
                     /translation="MMTREKEAYERFILLFVERFNQAFHTDYATNIFEDFENSYSYSV
                     ISSTDVYNYRVYLTIGLILLFLLLSSFFLLMNKEISLLLNNGFSLHQVLWCLLGKKKI
                     IITFIIAGIIGGFIFMYYKEQFLYLFQMYVFLFSGI"
     gene            complement(10329..10710)
                     /locus_tag="IXR40_001409"
                     /pseudo
     CDS             complement(10329..10710)
                     /locus_tag="IXR40_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339091.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            10836..11501
                     /locus_tag="IXR40_001410"
     CDS             10836..11501
                     /locus_tag="IXR40_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4361267.1"
                     /translation="MNIGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDL
                     EMLSLLHQTLGLPIDFPSIESATESIEPTLPDEPLVIKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETVDRFNPFLKPQIGYTTLPVGYVENSIEHWVCNDIFVHGTW
                     LSFHAGEVEKGKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILIQDYDDALKRSPQEP
                     DRH"
     gene            complement(11898..13931)
                     /gene="brxL"
                     /locus_tag="IXR40_001411"
     CDS             complement(11898..13931)
                     /gene="brxL"
                     /locus_tag="IXR40_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002397592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease Lon-related BREX system protein BrxL"
                     /protein_id="HAQ4361268.1"
                     /translation="MEQQEILKLSEFFPGKIVRKDLTKKIKEGANVPVYVLEYLLGMY
                     ASSLDETLVEKGVENVKNILARNYVRPDEAEKVKAKIRELGGYTVIDKVTVHLNEKKD
                     CYEAEFSNLGLKNVQISEEYPKKFDRLLGGGIWCIVSMEYWYDENDRWNSPFIAKKVD
                     PIQMPGLDIEAYKMARKEFTTNEWIDLLLRSIGMEPTQFNKRVKWLHLARLIPLIENN
                     FNLCELGPRGTGKSHVYKEISPNSILVSGGQTTVANLFYNMASRTMGLVGMWDCVAFD
                     EVAGIKFKDNDGVQIMKDYMASGSFARGKEEKNASASMAFVGNINQSVDVILKTSNLF
                     EPFPEVMGTDSAFLDRMHCYLPGWEIPKYRPDFFTNDYGFITDYFSEVMRELRKVSFG
                     DSFDKYFKLGSQLNQRDTIAVRRIVSGMMKLLYPDGRFEKSDVEEILRFALEMRRRVK
                     EQLKKIGGMEFYDVNFSYIDLEEEREEYVSVPEQGGGTLIPEGLGKPGHLYTVSYGKT
                     GQLGTYKLETQMTSGNGKFERTGINSDAGAREAMDSAYRYLRANYGSVSQSISLTTKD
                     FVVHVQDMNGIGMTKTLSLSTIIALCSVSLNKPVLPSLVILGDITIGGSMIKVDNLAN
                     CLQVAKDAGAKKVLVPMISAADIGTVPPELMGTFNLIFYQTPEDAVFKALGVE"
     gene            complement(14049..16571)
                     /gene="pglZ"
                     /locus_tag="IXR40_001412"
     CDS             complement(14049..16571)
                     /gene="pglZ"
                     /locus_tag="IXR40_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BREX-1 system phosphatase PglZ type A"
                     /protein_id="HAQ4361269.1"
                     /translation="MTDINTQQIEEKLNQRFPNYGCRKIIFWFDSNQDFLEEIDSLVI
                     QNAKIYRLEKDAQFKTKRLLEYEDPETNYLIYAPFPRWDDKDEDNHLLSVLNYSEEFS
                     ADRLAIIMNELAIPLRFHQTVKQYRNFFNAKDRMRSFGEFSTHMTINKSETIELMIMA
                     VLLKSKSIRLNDLLRVVLKSFTESRENPLRELDKYQLTAKFWEFIQMKFGFTDSQPTL
                     EKLTMCLYLNYFYYQIDQEMPKKFKGFEILHLKANIITFMDQFMNDTRYMESFEQLSK
                     KVYQAIDGDGLLDSIEIDDLIEADVFSEIHAKILMFYAERLKASDTTTKIAGQTIFDS
                     LKQREKMHFASDYIYEYQLLKHAYYLVDKNRLCLPMNMDNLLTQYEKEMYWVDTHYRK
                     FIWNSDHIEEKQKYGQLYRLVEANYSKFLDQSGQIWNQTFEFKNRPSIRKFYNQAVMK
                     RSVKTVVIISDAFRYELGMNLERKLVREKKYSTNMASFLSVLPSVTEFGKAALLPNNQ
                     LTYNEGTEVLIDGKKTNGLSNRNAILQQRDANAVALNYDDVVKMNKAEVREVFNGKSV
                     IYIYHDQVDRTGDHSNENRVFEACDLAISEISRLINRLHNDGSIYRFIVTADHGFIYK
                     RSHVEEVDKIENPSRNEKDRVERRFILSEEEYEIIGTKNYSLGDSLGNDDTRNICVPI
                     TSSIFKKAGGGQSYVHGGSSIQEMLVPVLEITVAKGSNAKEPVAIELMTSNRRITGLS
                     TTLEFYQKNAISDVYDPASFWLYFEDEYGERISNEEIYVADSKTEDANQRFTKFVFEF
                     VNRRYTVEDTYYLVIKNQKNDLTERIKFIIDNPFAESFDFDI"
     gene            complement(16687..20319)
                     /gene="pglX"
                     /locus_tag="IXR40_001413"
     CDS             complement(16687..20319)
                     /gene="pglX"
                     /locus_tag="IXR40_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BREX-1 system adenine-specific
                     DNA-methyltransferase PglX"
                     /protein_id="HAQ4361270.1"
                     /translation="MDKKAIKNFAVNARRKLIDEVMTKAKRLGIDESKIEDVKKIDSN
                     LQEIEKSGIRIQGKEIAQRNKLIAELKQRASVTSYSEAFQELIEEVAYTWFNRLIAIR
                     FMEVNDYLPDTYRVLSSEISGKIEPDIITDIYDADIFEELSSNEQQQVRTWKTDNSAE
                     AMDKLYQLIFIKICNQLNDYLPELFEEVEDYTELLFTASYIKKDGVIADLLSIPEDDF
                     YVQAGGQVEIIGWLYQYYNSEPHNQVVNIYKGIVKKQDIPAATQLFTTDWVVRYMVDN
                     SLGKYWLDHYPNSELRNKLKYLIPDKYAFEQATSVSNLKPEELKIIDNAMGSGHILVY
                     AFDVLMEIYLTLGYSERDAARAIVEYNLYGLEIDKRAYQLSYFAIMMKGRQYDRLFLK
                     KSLSPNLREFIDSPKVTDEYQERISELNNDKYSERWNEYKELIFDQFENGKELGSIIK
                     LVDKNNQAITKEYLGKVREYISKFNEFTNMDILYGMKEIQEKYLHILDVAEMLVDKYV
                     AVVTNPPYLNKMDKKLKKYVNDNYSDVKKDLFSVFIKLNSQMLIDNGYASFMTPFVWM
                     FISSYEKLRSFLINERNISSLIQMEYSAFEEATVPICTFTIKNSNEQDGSYIKLSDFK
                     GGMEVQKIKTLEAIHQHGECDYFYSTNQDNFKKIPGMPIAYWASDNVITDFAQGKLTN
                     DVADAKQGLATGNNNKFLRYWFEVEFNKIKFDAKTLEDAKKSRKKWFPTTKGGRFRKW
                     YGNNEYVVNWENDGDEIKNYVNENGKLKSRPQNLNYYFKKGITWSTLSSGQVSFRLQN
                     QAIFETKGSVLFSKDITDFEEIFGYVNSKLVNHFLTFISPTLDYHEGPMGKLPFLKVT
                     SERKLKKIREKVDENIDIARKDYNALETSYEFRRNILLSYMFKKDLSEAFNCLSRQLV
                     NQFNTLKSNEEELNDIFINHYSLEKELTKEVQDEYISARLPDKAREIKDFISYSIGCI
                     FGRYSLDEDGLIFAGGEWDPSRYQKFKPDTDNVLLITDDEYFKDSQIDIVNRFIDFVE
                     ITFGKETLEENLQFIADTLGGKGTSREIIRRYFVQDFYKDHLKTYSNRPIYWQLDSGK
                     QNGFKALMYLHRYTPDQLGKVRTEYLHELQKAYDNRIELRQQQISTSDNPKERNAMTK
                     EIVKIQKQLKEVREYDEKLGHLALKRIELDLDDGVIVNYDKLQRDPKTGEKFQIFAKG
                     VKEPKK"
     gene            complement(20383..24054)
                     /gene="brxC"
                     /locus_tag="IXR40_001414"
     CDS             complement(20383..24054)
                     /gene="brxC"
                     /locus_tag="IXR40_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BREX system P-loop protein BrxC"
                     /protein_id="HAQ4361271.1"
                     /translation="MLIKDIFAKPIDRNIQGVIKVGQAKDENVQQELEEYVVTKELQK
                     HFKTIFDAYQRSINTPTDKMGVWIQGFFGSGKSHFLKIISYLLANREINDKKAIDYFK
                     EDGKIKDPLTLATMERCSQINTDVILFNIDSKSDAGGKKDKNGIVNVFLKVFNEMQGL
                     STIPHLADFERRLIKEEKFDAFKAAFEEINGAKWQEERHEFDWIQDDIKEAALKIDFM
                     SEAAIDNFLEKASGNYLISIDDFANLVKSYLDSKEADHHIAFLVDEVGQYIGGNRELT
                     LQLQTVVEDLGRICEGKAWVLVTSQEAIDHVTNFDNNSDNDFSKIKDRFATTVSLSSA
                     NADEVIKERILKKKEFANDSLALQFETVQTELKNKLLFVDSPELKLFQDAENYAEVYP
                     FIPYQFNLLGQILTEIRNHSYQGSNLSSGERSLLAMFKEAAERNKENDTTSLVSLDQF
                     YYSLERWIDTAISRVITQATNNSHIQRPTDIDNFNVNVLRILFMIKYVDQAIKPNVEN
                     ITSLMIRNINEDRLETKKRVEEALDLLIKENFVRKNLDSYIFQTDEEQEITREIKNQN
                     ITDSDLIVELSKRIFDGVLDRNSFAYEKLGMSGGNKFKNRYTFTYAQVLDQRPYKQAG
                     NAEMTVNFISPYSDLAGQEAELALKSSRNLLFVELPSDKEFKDDIAMYARMNLYLTTT
                     YSSVVKNFDAIRSEKSGELQELSASINDQLNELLKSAKFFYNGAEIQLTGSDFKAKFQ
                     SALQKMAEEVYHKLNQIDAPKEKEDILYLVKESKNEIIEDPSNEQAVQEIFNFINDQK
                     RNHLTITMKTIRDRFETKQPYGFTELDVEWCIAKLFMSGKIDLLYNNVQISRMDDPNS
                     IVMIIQKRRESEKIKIEPSAVISPKAKKLVDEIGRELFQSRNIVDENNNEHTMENFKK
                     YLKGQLDNLRSYFDLQNTYTYPSAYEYEQIKKYLEVIVQTSDVEDFFYTIKKYRDELF
                     DWAETYDKIKNFHKQNSTQKKIWENAQDKIRLIEKSRRQTSSQEIDQLIHEMKTILKK
                     ADPYSDMMKLNELIQEFIEQYNQLLELESQEILNKLTEEKQATFKLLEGKDFKDQFVP
                     IVDQEFQELKAKIEQANTIDDLVFLSLNVAEQYLIFNQRFDNEENRRRQEEQARKQIE
                     AANLIRETEKDEIDSAAKAEEIAIVKPTIQQKTVPMRTLNVHVKTIKSAADIDELTAE
                     INQKLKEQLQENTEITIQF"
     gene            complement(24079..24654)
                     /locus_tag="IXR40_001415"
     CDS             complement(24079..24654)
                     /locus_tag="IXR40_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1788 domain-containing protein"
                     /protein_id="HAQ4361272.1"
                     /translation="MSLSIQEHLEKLNEVIQKEDFLLNRGLGNEVGYYIFDYDPKDEL
                     IVRDYINDISGTSVGDNYEVKVYNLYVIMLEYLEKRGFTEKAIKMEERRGLQKLVESI
                     GRLLKMDLPEEENVFFEYVDAHTPEKSVVFLTGIGELYPLIRAHSILNKMHQVFDRVP
                     VVMMYPGEYDELSLTILNTNKDDNYYRAFRI"
     gene            complement(24654..25253)
                     /locus_tag="IXR40_001416"
     CDS             complement(24654..25253)
                     /locus_tag="IXR40_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1819 family protein"
                     /protein_id="HAQ4361273.1"
                     /translation="MNKKYSAGLVSKRFWFSEFKLYIQLRLEGYTDIEIKEKNEHENI
                     FFAVSSNRQKEIYQNVKRRVSQLDEAGLQLFNQLNIDNQKLVNLISILMIDDLFNEFM
                     TEVYAENLRKGNLQLTPVDYRSFFTEKRRSSEDISKWKDYTIKRLIAAYQTNLIETGL
                     VRGEKEYGRMTPILLDKRLIQWLVDKNRKDIVLALGGIL"
BASE COUNT         7761 a         4946 c         3829 g         8823 t
ORIGIN      
        1 actaacaaat gcacctcaag atatacttga gctatcaaga agtctggagg ttttctatgt
       61 ataaattaaa tgagattgtt cctgtccaat taggaaacga aaagagtgca ccagaaaaag
      121 gtaaacccgc ggctgccaag ttagcgatgc gcatcaaaag agagaatggt tctgaagttt
      181 tgatctataa cggtattaac aattatattc ttcaagctat tttgaaagaa ctgttgtcca
      241 atgctttatg atttacttca aaccaaacat atttatattg tgtgcggaaa aacagatttg
      301 cgaaaaggaa ttgatggtct tgccagtctt attcaacaag agtatcaact cgagctttac
      361 gaagatgccg tttttttatt ttgcgggaac cgtcaagacc gtttcaaact tctctattgg
      421 gacggtgatg gttttcttct ctgttataag cggatagaaa acggcaagtt aaaatggcct
      481 cggacgaaag acgaagttcg aaccttaacg aaccaacagg ttcgatggtt gttagaagga
      541 ttaagtatcg atcaacctcg agctattttg ccaggaaaaa aaggagtttt ttaagctggg
      601 gggttaacac aaaaaatgtg ttgaacccct atttcttgtg cgtttcttgt ggtattctgt
      661 aacaaaatca gttcgattca aggtggtgaa aaattttgga aactacagat acgttgcttc
      721 agttgcttca agaagcccat aaaaccaatc aagcacaaca acaaaccatt cagaatctta
      781 caactgaaat ccaactattg aatgaaaagg tcaattattt aaccaacaaa ttatttggac
      841 gctctaaaga gactctcttt gaggaaacga atgggcaatt gaatcttttt agtgatgaag
      901 aaatttctgt aagtgttcca gaagcagctg ccaccattat tccagtaaaa ggacatcaac
      961 gagttgtagg aacgaaagca gacaaaatca aacacttacc tataacagag aaagaacatc
     1021 tccttccttt ggaagaacaa ttttgtgaac attgcggttc acagatgaaa gatatcggac
     1081 ggacaaaagt acgagaagaa attcgtttcc atcaggctat gttggattgt ctcacccatt
     1141 atcaacatac ctattgttgt aaaagctgcg aaaaagaagg actttcttct tttaaaaaag
     1201 cgatcgttcc taaacctttg atttctaata gcttaggttc caatagttta gtggcggaaa
     1261 cgatccggat gaaatttggt cagaaagttc ctgcctatcg gcaagagaac tattggaaac
     1321 aaacacatgg gttggatatt tcgagagata atatcaccaa ttggcatatt aaagcagtgc
     1381 aaaacgcgtt agacccttta ggagaacgat taagagtcta tcttaatcaa gaagagattc
     1441 tacacgggga tgaaacaagt tatcgtgtga ttgaaagtgc caaaacagat acctattact
     1501 ggcagttttg tacaggaaaa gacagtcagc atcccatcgt ttattatcac cacgacgaaa
     1561 gtcgtgctgg agatgttccg aaaacttttc tcaaggagtt tacagggtat ttacactgtg
     1621 acggctatag cgggtataat gccgtggaaa gtgtacgact tgtctattgt ttcgcgcatg
     1681 ttcggcggaa atttttcgaa gcaattccaa aaggaaagaa aaacacggat attcccgcag
     1741 ctcaagcagt caaacaattg gataaatggt ttgtcctaga aaagaaatgg aaagactttt
     1801 ctcctgagaa gcgattaagc tgtcggcaac aagaactgcg tccattattt attgcttttt
     1861 atgagtggat ggcaacgata gatcctgttg caaaatccaa gttggatgca gccgttcaat
     1921 atgcgtgtaa actacgaagt ggttttgaac ctatttttga agatggtcgt ttagaactca
     1981 caaataatcg tgcggagcga aatatcaaag agctggtgat aggacggaaa aattggttgc
     2041 attccacaag tcttgaagga gcacgaactt caggaatcat tctgagtgta tataaaacag
     2101 cagaacttaa cggattgaat cctgtaaagt atctagagtt tctatttgat aagataccaa
     2161 atcttcccgt actttcagca gaaactttag atcaactgtt gccttggaac aaggatgtac
     2221 aacaacattt ttctcgtaac taaaaacgcc aaacattccc gattctattc tataggtcgg
     2281 gttatttgac gtacaggtac tgttctatgg ggcgcttact tttctgggat agaaagaaca
     2341 aatttacctg tatcatcaat agttgtttcg gacaaaacag cttgattttt tttcaatgaa
     2401 accaaagctc ctgcttcgcc tgtacctgtg attgagcgag aagctgcatt gatcaatgtg
     2461 gtacttaatt tagcaggctc aggaggaatc acatcgactg tcgttttggc agagtccagt
     2521 tctgtcactt cttggccgcc tcttactttt ttagcagcaa ctatttgcac ttgatccccc
     2581 gttgttagtc tttcttcgtt gggtacttga acctcaaaca aaccgccttg ttcgccttct
     2641 ccccacggat tatatcctgt cccttcattt tcatctgttt gtccttgtgt gagagcagta
     2701 atttctacag gtgatttcgt cgtatctgca taagtaatac gtaaagtcac ttctacttcg
     2761 cctgtccaag catctcttgg ctttgcctcg acaccttcgg gaacaacgac atgcccatag
     2821 atttttttat ctgcattcgt tggtactctt aaggattcaa tcatcggaag ctggttattg
     2881 gcactgattc gattataatt tttcattccg gcacctgtct gagcaaattc atttgttaaa
     2941 cctgcactag ggcttgatac aaaattacct aagtcggttc cattgatcga taagtctgtc
     3001 atatcagaaa aataatccgg atctttttca aagttatcga acgttactcc tgcctttcgc
     3061 cataaagcaa tttctgaatg agcgatcttc aaagaagaat cgccatttcc ttgaaatacc
     3121 cagccaccta tgccattagt ctcgcttccg atccgtttgt tttggaaatc gaaataggta
     3181 ggagattcta agtctacatt caacacatcc ccactgatga tgccagtctt atcttcccca
     3241 gttttcccga ccatgactaa ataagttttt tcgccagcca taaagttcaa atcaatatct
     3301 ccagttgtat ctacggtagc tccggaatct gcgcgtatat cgatatttga tttttctcca
     3361 gtaaccgtaa aatcagctga ccctggactt tctagaaaac cagaagcgtc ataaaattgg
     3421 atcgcttggt ttccttgatt gagtctgttc acataagatt tgccatcccc tgcatttctt
     3481 accttcaatg agcctccatt agttactgtt agtttttgcg taccgttctc aaaacgaact
     3541 gcgctagaac gaccactttg cttatcaata tcgatgactg atccggctcc ttctacgatc
     3601 aaagaaagtc ctttccctac aaaacgcatc ccattgtttc caggttggtc gccatctcca
     3661 gccattttga ccgagatttg tccaccactt gatacatgga tttgactaga atctccttgc
     3721 aggcgaaatc cgccagtagt cgctgtattg attgtgattt tcccatcatt cgacacagcg
     3781 actcttgatc ctgagcctct catttggata attccgcgat tgttgtcgtt ggtaatattg
     3841 atctttgtat ttaccgaaaa ttcacttcct gagccactga ctttaaatgt gacattcccg
     3901 ggtagcgtat cgacagcctc tccttcatcg ctgacgccat ctgcccgatc atagtcaaga
     3961 gagacctttg aaccactcaa gatatggagt cctggtgctg tttttccact gcccgtctca
     4021 tcacctgaat ctagaaaacc atagaatttt cctagatatg gtccataaag ctgactacca
     4081 ttgattacat ttagctgata gcttctacaa aaataagctt tacccggagc ggcattcatc
     4141 ccttctttca ctggttggac atccaataca ccggaaacac catctaatgt gacagttgca
     4201 cgaggggcgt aaatcaggcc taatttagaa ccatcatata agtcaagtgt cccggtaaat
     4261 tttatttctc ccgtaaaatg atatctgttt ccccaaaaat cggacatata agcaatgata
     4321 atggcatttc catcgatatt tggtatcaac ccacctggat gagctgccgt tcctttaaaa
     4381 ttctgaaact cgatcgactg aggtgtctca ttgatataga tgtgatgtgt gccgaaatta
     4441 tgagcaagtc cgccaaaatc gataacgata tctcgcttga tctccaattc cctgtctaaa
     4501 gtcaaaggct gagttaaacg aatcttagct actgattcgt ctgcgagaag ctgcgtcagt
     4561 tcttctgttg tggcagcttc gctgtaccca tccgctgaaa caactctaac ctgtacctct
     4621 tcactgctat cagacgtttg ttcagctact tctgaggtct cacttgtctt attttcttct
     4681 tgccttgtat tagaagtagg cgcctcactt tgggattctg tagtttcaga agtaattgat
     4741 tcttctgaaa aagtagtctt gtcaaaactt tgattctctg attgcgttga ttcgcttgtt
     4801 ttctctacat cggcaaaaac ggatgtcacc atcaagagag ggaagacaaa caaaatcgac
     4861 gcaatcagct tttttacata ttgattcatt ctccaccatc ctctctgacg ttttgacaat
     4921 tttattttaa cgttttaatt tatttgtaat tgtactttca tatttaaaat atgtattttt
     4981 atggcaaatt tttctgttag gtgaaaattt cttttttgta caaaaaaagg ctgtgacaaa
     5041 agtcttgtca cagtccctta ttccgaacaa ccgatgtcct cctgacaact cttcggtcac
     5101 aacctccatt ttaacaataa acctgtaaat gtgagggtaa cactttgatt gtcacaggta
     5161 atttatcccc ttcatctcca tcaacattcg tcgtcaattc ttcctcatca gctaatgaca
     5221 caactaattg ctcacaagta agataggcta gatttttcgt agattcatct actcctttta
     5281 ataggtctgg caatgtttta agcgtatcga tcaaagaaga atcttttaaa taaaccaaat
     5341 ggagcttacc atcatccact tttgcatttg gaagtaatgt ttcaaaaccg cctactgagt
     5401 tagttagtcc tatcagcaag atactgctct caatttcttc cttctttcca tcaacttcta
     5461 cgtgaaacga gtaggattgt gtggaagcta actgtttgat tcctgacatg aaataagcta
     5521 gttttccaaa tttcgtcttc ttctccgcat ctacatcatt gattgcttca gggatagagc
     5581 caattgcgac gacattcata aaatagtcgt catttatttt tccaatatcc aatggcttga
     5641 ctgattcaat cgaaaaatga ttgatcgctt cctcaggttc tagcggtatc cctaatgctc
     5701 gagccaagtc attcaccgta cccaatggga aaaatccgaa atttggccga tgttcttgtt
     5761 cagcgattcc actgattcct tcgttgactg ttccatctcc gcccatgaca aacacactat
     5821 gatacccttc cgtagccgct tcgcgagtaa agttttttgc atcccctgct ttttttgtat
     5881 gcaagacgac cacttcatca aacaccgatt ccaattttgc tatcgctaat tgctcaaatt
     5941 cctttgcttg ttcaccgcct gaactggggt ttaccactaa taaaactttt ttcatcactt
     6001 tctttccctt ctgattgatt tctttaatat aacgatagca taaagaaaaa aattaggctg
     6061 tgatgaagta ctgttcatga aacattcatt tattttttga caagataaaa tacccatact
     6121 atgaaactga ggaaaattaa aacaatgata taggaaataa aagaaaatga taggcattgt
     6181 atacctaata aagtaaaaat cttaggtggc agataaaaac acaaaaatag caagagaatg
     6241 taatagcgtt tcttccactt tttgttatca gaccttatag cgatcagagg aataccaaat
     6301 gcataactga aaaactcttg atgtactgtt aatatgtcac gaccttgaat aataaatgca
     6361 acaatccccg ctataattag tgtgcctaat accaaaacgg aaaattgatg aatatatttt
     6421 atatacaaat gatccattgt acttcctgcc tttttatttg tgagaaaaac aaatccgtat
     6481 acgtgaataa cttctagaaa taaaagaaat ttgcaaaacc actccattta tctacttcta
     6541 cgtgcatttt ttaatatcgt tttctttatt taagattata cagaaaaata tctagggtgg
     6601 ctggattcta agtaaaaaaa atttttaaaa taaaaagaac taaatcaagt aataattaaa
     6661 ctactgttga tttagttcta ataaaaagat ttagatgaac agttttattg atttaaatag
     6721 ttcatatttt ttatttatac cgcttattta ctacttgctg tactagaatc tgaagtgaat
     6781 gtactcaaaa cattttcaaa gtctttgtct ttgattttta cattagcgtc tttcaatact
     6841 tcgccaatta ctttattctg gaaggtactg tcacttaatt ttgtgtctgt tgcaatttct
     6901 ttcaattctt ttttgtattt atccatgtcg ttgcctttgt tttggttttt caccatttta
     6961 accacataat attccgtagt ataagttgaa gcattggtag aagtgatcac atcagaaact
     7021 tgaccatctt tcaacttaaa ggctgcttct ttgacttctg ccggaaccgt tgtagtagtg
     7081 gaatcaaatt tcacttttcc gccatcttct tttgtcgtag tatcagttga cttgtctttg
     7141 gctaatttag agaaatcgtc tcccttatca gcagctttct tcacatcttt tgcatcatct
     7201 tcacttgcta cttggataat ttgagcttcc acttctggat ggaaagattc ccaagccgtt
     7261 tttaaatctt catcggtcaa tttgatatgt ttctttagac cttcttgaaa ggctagactt
     7321 tgtttgatac tgtctttgaa tgtttgttct gtgtaacctg cagatttcaa ttgtgaatca
     7381 aatgaatcac ccaattgttt ctttgtttga tcatattggg aatcgatttc tttggttgat
     7441 acgtcatctc catatttatc ttcaaatact tgataaacga tcaactgttg cacagcggaa
     7501 tctgctcctt gcattttttt caagctatcc attacttctt gttcgctgat tgtaccgcct
     7561 ttataactaa cggctgtttt ttcaccggca ttcgtacagc ctgacaataa gccagtgcct
     7621 agtacgatgg caagtgctaa aaatcttttt ttcatttatc aattctccta cttttcgttt
     7681 tttgcgaatt gctaaaaaca aaggtgttca agatgaaaat catcaagaac acctttacta
     7741 atctgctcga tacgtcctga atagatataa ggctacacaa tccagaaagt tcgctcagca
     7801 gaataaatgt caagtagcac atcacacctt aatatactac ttcttttgtt accgtttttc
     7861 aagtctatct tgcgttccgt atttaacgta actaattctt agaacaaatg ttatcgattt
     7921 tgtttttctt cttccgctgt tgggatattc aaatcagaca cttttatgtt cgattttcca
     7981 gacatttttt tgttgttttt attagaaaaa gtttgttttt tcatttgttt tctaaagcat
     8041 gatcttcttg tttcctattt tggtcagata tggatcatgc gtgaccacga taactaacgt
     8101 accttgggaa gcctgttgcg ataagatttc aacgacttgc tccttatttc gtttatctaa
     8161 tgatccagtt ggttcatcgg ctaaaatgat tttgctattc ttcaataaga ctctcgcaca
     8221 ggcgattctt tgcttctcac caccagataa tgtgtagata ggcgtactta gcttcttgtt
     8281 tatatttact tttttcaatg cctcatactt tgctgttcgc ttatctgaaa catttaaatt
     8341 cgaaaacttc aatccaatat ctaaattaaa atcgattgtt tcatattcaa tcaacccaaa
     8401 atcttgaaaa agaaaagaga gggcatttct ttttatcaag cgcttctctc ttccagttaa
     8461 atgttttgtt tcttgattaa ataaataaaa ttgccctgaa ctgaattgat cattcaatcc
     8521 taatatattc aataaagtac ttttccctgc tccgctctct ccaactacag tcacaaaatc
     8581 cccagcatcc gcagtgaaac gatccaaatg aagaatcgtt ttgtttcgaa tgattttttt
     8641 cgcacctttt atcactatca acggctccaa ttgttaacct ccattcatca gcaataactg
     8701 acttttcttt tctgtagaca aaataaaaac aactgaaaga ataaaatcaa tgaagctaaa
     8761 gaaaaaaata ttaaaaagat atttaggctc tctttctata agaaaaagga agattacact
     8821 tgtcgttccc catttgatga ggttcatcat gaagaaatct ttatacgttt caaagagcga
     8881 ataaccactt gaacgaaaga tagcgatttt ccgacaattg tagacaaaat atatgcataa
     8941 catgacatag ctcaacaaga agaaagaaaa gaaagtgagt aaaaatatct gtatcaagta
     9001 atgaaatgat ctgcttaaca ctttgacagc tatctcttca gtctgagtat acggaaatga
     9061 taactgcaag ttatcacgta actgactttc ttcaatcagc tcaaataacc tttctttcga
     9121 caaagagcct atcttgatct ttaacggtgg atagatttct ccgctgagaa tatttctttc
     9181 ccaatacgta ctgtttttca atgtcagtat ttcaacaacc ggataatgtt cgatccaggg
     9241 gatagaagga ataaatgtat aaatgggttg attgtttttt ataaatagaa atttcggttc
     9301 tttttcactg atttcttgat aatattctgt tatttgcgcc aggtcatttt ttaaatctgt
     9361 atgtctatat cgttcaggga tcaatataac agggtgcgtt tctttttcgg ttatttggat
     9421 caaccttcca gagacatcaa tcaaaggaaa tttcttaaga taattcagat ttatttttat
     9481 ccctctgcca aactgttcat tttcttcatt caagtaatct gatacattga ctaatatact
     9541 tccgttttta ttcaaagttt catataattc ctgatcggct gctgatgcaa aacgattgga
     9601 ataaataaaa tccacgtggt ttttcccgat ggttactgga taaaatacat gatagtcctc
     9661 accagcgatt tcttttggtg tttcatggga aacagctaac tgtgaagaag aaaaaacgat
     9721 agttgctaat tcgacattgg caacggtcaa aagaagagaa aacaacaatc caaatgtaaa
     9781 aagaatgtat tggatatagt tgaacgcttc tcttaacgaa gcgatttttt caactaataa
     9841 aagagaaatc aaagagatac cctatattcc gctgaacaag aaaacgtaca tctggaacaa
     9901 ataaagaaat tgctccttat aatacataaa aataaaacca ccaatgattc ctgcaattat
     9961 gaatgtaata atgattttct ttttccccaa taaacaccac aatacttgat gtaatgaaaa
    10021 gccattattc aacaataaac tgatttcttt attcatcaat aagaaaaagg atgataacaa
    10081 aaggaataaa agaatcaatc caatagttaa atacactcga taattatata cgtctgtact
    10141 tgaaataacc gaatacgaat agctattttc aaagtcttca aaaatattag tggcataatc
    10201 agtgtgaaat gcttgattga atcgttccac aaatagtaaa atgaaccgtt cataggcttc
    10261 tttttctctc gtcatcaaga aaaattcacc ttcaaaatct tttattttga tcgattcttc
    10321 aatggacgtt acgcgaaagg aggtattaga atagggtacc ttctcgtgag aagatttgac
    10381 atccccttga taatacaatg tcatttcaag ctttggctgt atcttgaagt tccaagatgt
    10441 atctacttca ttggattcat ttactgtttt tttcatataa gaaagctcag tttctgatga
    10501 gacattttca aataccatga ttagctgctc atattcttct tgcccaataa aatgttgtgg
    10561 caatcgaatc ggagtataag tatctgtttg atggaaaaat tcatttgtcc gatagagtac
    10621 ctgtttattt ataataacca aggcaaaacc actcatgata ccggtcacta tgattgtgag
    10681 taaaactgtg aacttttttt tgattatcac cactctccct tacttaaatg attctttgat
    10741 aaaatcatac cgtttttcat caaaaaaacg tatctatcaa atgtataggt catgtagaat
    10801 aaatctatat actgtagaat cgaaaggaga agaagatgaa catcggagaa aaaatacgaa
    10861 cttaccgcag aaattgtaag cttacgcaaa aagaattagg cgaaaaaatc ggtgtttccg
    10921 ataaaacaat ctctagttgg gaaaattctc gtacaatgcc agaccttgaa atgctgtcac
    10981 ttttacatca gactttaggt ctgccgattg attttccttc tattgaatca gctaccgaat
    11041 caatagaacc aacattgccg gatgaacctc ttgttatcaa gaaatcttat tcatcaaaac
    11101 aacccttctc actcaaaaag acactatctt tctttctgct cgtcttttgt ttggtctatc
    11161 tttttcttat caattatcaa tataaaaatg aaacggttga tcgattcaat ccttttttga
    11221 aaccacaaat cggctatacc acactccctg taggatacgt ggaaaattcc atcgaacatt
    11281 gggtatgtaa tgatatcttt gttcatggta catggctgtc ttttcacgct ggagaggtag
    11341 aaaaaggtaa gaatcatgct gtaatcaaac acaaaggaaa acacgtcatg aacgttcgcc
    11401 tgctcacttg ggaagccatt ccctcagatt accaagaaat cctcatccaa gactatgacg
    11461 atgccttaaa aagaagccct caggagccag ataggcatta agtaggagat gaacgtagag
    11521 atagaaaaaa tcaatgcaca tgatcttatc aaaaaaaaac aggggtacaa attaattgaa
    11581 aaagctttga gatgaaagtt cctaaataaa aaagttcaga atgataggta aaaaaatgac
    11641 taactattct agtattaggc tatttgtatt attcttctgt tatttttata tcaaaaaatc
    11701 cagaaataac taaatatagg tatttctggc ttatagtata atatttacgc cacagccccc
    11761 aatgattctt tttggaatca tgatcaagga cggacataca caaaaatatt ttgcccattc
    11821 gatccgaata gattaacgac taatctagta agtaatatag attggtacgt agtcaaacca
    11881 gcaaatggaa aagttgtcta ttccacccca agggctttaa agacagcatc ttccggcgtt
    11941 tgataaaaaa tcaaattaaa ggtacccatt aattctgggg gtacagttcc aatatcagca
    12001 gcgcttatca taggtacaag tacttttttc gctccggcat cttttgctac ttgtaaacag
    12061 ttagctaaat tatctacctt aatcatagaa ccaccaattg taatatcccc taaaataact
    12121 aaacttggta atacaggttt atttaaggaa actgagcata aagctattat agttgataac
    12181 gataatgttt ttgtcatacc aatgccattc atatcttgaa catgaacgac aaaatctttt
    12241 gtcgtcaaac taatagactg actaacactt ccataattag ctcttaaata tcggtatgcc
    12301 gaatccatcg cttctcttgc tccagcatct gaattgatcc cagtacgttc aaactttcca
    12361 tttcccgaag tcatttgcgt ttccaattta taggtaccta attgcccagt tttgccataa
    12421 gataccgtgt acaaatgccc tggcttccct aacccttctg gaatcaaagt tcctccacct
    12481 tgttcaggaa cagaaacata ctcttctcgc tcttcttcta aatcaatgta tgaaaaattg
    12541 acatcataaa attccattcc accaattttc tttaattgtt cttttacacg acgacgcatt
    12601 tcaagagcaa atcttagtat ttcttcgaca tcactttttt caaatctacc atcaggatac
    12661 aacagtttca tcatcccaga tacaatccga cgaactgcaa tcgtatcccg ctgatttaat
    12721 tgagaaccaa gtttgaaata tttatcaaaa ctatcgccaa aactaacttt tcgaagctca
    12781 cgcatgactt cagaaaaata atctgtaatg aagccatagt catttgtaaa aaaatctggt
    12841 cgatatttag gaatttccca acctggtaaa taacaatgca tccgatccaa aaaggctgaa
    12901 tccgtcccca taacctccgg aaatggctca aataaattcg aagttttcaa tattacatca
    12961 acgctttgat taatatttcc tacaaaagcc attgatgctg aagcattctt ttcttctttg
    13021 cctctagcaa aagatcctga agccatgtaa tctttcatga tttgaacgcc atcattatcc
    13081 ttaaatttaa tcccagcaac ttcgtcaaaa gcaacacagt cccacatacc tacaagtccc
    13141 attgtacgac tagccatatt atagaaaagg tttgctactg ttgtttgtcc acctgaaaca
    13201 aggattgagt ttggtgaaat ttctttatat acatgcgatt tacctgtacc acgtggtcct
    13261 agttcacaga gattaaaatt attttcaatt aatggaataa gtcttgctaa atgaagccat
    13321 tttacccttt tattaaattg tgtaggttcc ataccaatgg accgtagaag taagtcaatc
    13381 cattcatttg tagtaaactc cttgcgagcc atcttgtaag cctcaatgtc taaaccaggc
    13441 atttggattg gatcaacctt ttttgcaata aaagggctat tccaacgatc attctcatca
    13501 taccaatatt ccatcgaaac aatacaccag atccccccac ctaataatcg atcaaatttt
    13561 ttcggatact cttcactaat ttgaacattt tttaatccca ggttagagaa ttctgcttca
    13621 taacaatctt tcttttcatt taaatgtaca gttactttat caataactgt ataaccaccc
    13681 aattcacgaa tttttgcttt tactttttct gcttcatcag gacgcacata gtttcgagca
    13741 agaatatttt taacattttc cacacctttt tcaaccaatg tttcatccaa tgacgaagca
    13801 tacataccaa gtaaatattc caatacataa acaggtacat tcgcaccttc tttaattttc
    13861 tttgttaaat cttttctgac aatctttccg ggaaagaatt cagataactt taaaatttcc
    13921 tgttgttcca ctagaattcc tccatgtgtt cagtcattat aatagcaatt aaagtatatc
    13981 atacttaacc agtaggcttg ataatacaaa agaaaaagta tccacaaaaa attgtggata
    14041 cctcgttttt atatatcaaa atcaaatgat tctgcaaaag gattatctat aatgaatttt
    14101 attcgctcgg tcaaatcatt tttttgattt tttatcacta aataataagt atcttcaact
    14161 gtatatcgac gatttacaaa ttcaaaaaca aatttagtaa accgctgatt tgcatcttct
    14221 gtttttgaat ccgcaacata gatttcttca tttgagatac gttcaccata ttcatcttca
    14281 aaataaagcc agaaagatgc ggggtcataa acatcactaa ttgcattttt ttgatagaat
    14341 tctaacgtgg ttgataatcc tgtaattctg cggttgctag tcattaattc aattgctact
    14401 ggttcctttg cattgctacc tttggctacc gtaatttcta gaacagggac tagcatttct
    14461 tgaatagatg accctccatg aacgtagctt tgtcccccgc cagctttctt aaaaatactt
    14521 gaagtaatcg ggacacaaat gtttctagtg tcatcatttc ctaaagaatc tcccaaagag
    14581 taatttttcg taccaattat ttcgtattct tcttcactaa gaataaaacg acgttctaca
    14641 cgatcttttt catttctaga tggattttca atcttatcta cttcttcaac gtggcttctt
    14701 ttataaataa atccatgatc agccgtaact ataaaacgat agatactgcc atcattatgc
    14761 aagcgattaa taagtcggga aatttcgctt atcgctaaat cacaggcctc aaaaactcga
    14821 ttttcattcg agtgatcacc tgttctatcc acttgatcgt gataaatata aatgactgat
    14881 ttgccattaa atacttctcg tacctcagcc ttattcatct taaccacatc atcataattt
    14941 aaagctacag catttgcatc tcgttgctgg agaatcgcat ttcgattgga taaaccattc
    15001 gtttttttcc catcaatcag tacttctgtt ccttcattgt aagttagttg attgtttggt
    15061 aataaggcgg ctttaccgaa ttcagtaact gaaggtaata cagaaagaaa gctagccatg
    15121 tttgttgaat acttcttttc tctaactaac ttacgttcta aattcatccc taactcatat
    15181 cgaaaagcat ctgaaataat aactacagtt ttaacagagc gtttcattac agcttgatta
    15241 taaaattttc gaatggatgg acgattctta aattcaaaag tttgattcca aatttgtcct
    15301 gattgatcaa gaaacttcga ataatttgct tcaactaatc gatacaattg gccatatttt
    15361 tgcttttctt ctatatgatc actattccaa ataaatttcc gataatgcgt atcaacccaa
    15421 tacatttcct tctcatattg agttagcaaa ttatccatgt tcatcggcaa gcacaatctg
    15481 tttttatcca caagataata agcatgtttc aataattgat actcataaat ataatccgat
    15541 gcgaaatgca ttttttcgcg ctgctttaaa ctatcaaaaa ttgtttgtcc tgcaattttc
    15601 gttgtagtgt cagaagcctt taatcgttct gcataaaaca ttaatatttt tgcatgaatc
    15661 tcagaaaata cgtctgcttc aattagatca tcaatttcta tactgtctaa taatccatca
    15721 ccatcaatag cctgatatac ttttttagat agctgttcaa agctttccat gtaacgtgta
    15781 tcattcataa actgatccat gaaagtaata atgtttgctt tcaaatgtag tatttcaaat
    15841 cctttgaact tcttcggcat ctcttgatca atttgataat aaaaatagtt caaataaaga
    15901 cacatcgtca gcttttccaa tgttggctgg ctatccgtaa agccaaattt catttgaata
    15961 aattcccaaa atttagctgt taactgatac ttatcaagtt cccttaaagg attctcccta
    16021 ctttctgtaa agctttttag aactacacgc agtaaatcat ttaatcgaat acttttcgat
    16081 ttcaacaaaa cagccattat cattaattca atcgtttctg atttattaat tgtcatatgc
    16141 gtactaaatt caccaaaact tctcatgcga tcctttgcat taaagaaatt acgatactgt
    16201 ttaactgtct gatgaaatct aagtggaata gccaattcat tcatgataat cgctaagcgg
    16261 tctgcactaa attcctctga ataattcaat acactcaaca aatgattatc ttcatcttta
    16321 tcatcccaac gaggaaatgg cgcatagatt aaatagttag tttcgggatc ttcatattcc
    16381 aataaacgct tagttttaaa ttgtgcgtcc ttttctaatc gatagatttt tgcattttga
    16441 atgaccaatg agtcaatttc ttcaagaaaa tcctgatttg aatcaaacca aaaaatgatt
    16501 ttcctacatc cataattagg aaaacgttga tttaattttt cttcaatttg ttgcgtattt
    16561 atatctgtca tcaatctcac ctaatcgttc tctttctata ccccttatat tgacataatt
    16621 tggataattt cgcacgcaat ttaagaataa aaaagaaagt tgttagaaaa caactttctt
    16681 agataactat ttttttggtt ctttgacccc ttttgcaaaa atttggaatt tctcgccggt
    16741 tttaggatca cgctgcaact tatcataatt gacaattaca ccatcatcta agtctaattc
    16801 aattcgtttt aatgctaagt gacccaactt ctcgtcatac tcacgaactt cttttaattg
    16861 cttctgaatc tttacaattt cttttgtcat tgcatttctt tcttttgggt tatcacttgt
    16921 tgaaatttgt tgctgacgca attcgattcg attgtcatac gctttttgta gttcgtgtag
    16981 gtattcagta cgtacttttc ctaattgatc tggtgtatag cgatgcaagt acattaacgc
    17041 tttaaagcca ttttgttttc ctgagtccaa ttgccaataa attggtcgat tggagtatgt
    17101 ttttaaatgg tctttgtaaa aatcttgtac gaagtaacga cgaataattt ctcgacttgt
    17161 ccctttgcca cctaaagtgt cagcgataaa ctggagattt tcttcaaggg tttctttacc
    17221 aaaagtaatc tcaacgaaat caatgaaacg attgacaatg tcaatttggc tatccttgaa
    17281 atactcatca tcggtgatga gtaaaacatt atcagtatca ggtttaaatt tttgatagcg
    17341 ggaaggatcc cattcgccgc cagcgaagat gagaccatct tcgtctaggg agtaacgacc
    17401 gaagatacaa cctattgaat aagaaataaa atccttaatt tccctcgcct tatcaggtaa
    17461 ccttgcagag atatattcat cttgaacctc ttttgttaat tctttttcaa gagaataatg
    17521 attaatgaat atgtcgttca gttcctcttc attcgatttt agagtattaa attgattaac
    17581 caactgccta cttagacagt taaatgcctc tgagagatct tttttaaaca tataacttaa
    17641 caaaatgttt cttctaaact cgtatgacgt ttcaagagca ttatagtctt ttctagctat
    17701 atcgatattt tcatccactt tttctcttat tttttttaat tttctctcag atgtaacttt
    17761 aagaaaaggt agttttccca ttggtccttc atggtaatcc aaggtgggag aaataaaagt
    17821 taaaaagtga ttaactaatt tagagtttac atagccaaat atttcttcaa agtcagttat
    17881 atcctttgag aacagaacag atcctttagt ttcaaaaatt gcctgattct gcaatctaaa
    17941 agatacttgt ccagatgaaa gtgtcgacca agtaattccc tttttaaaat agtaattaag
    18001 attttgtggt ctagatttta acttcccatt ttcattaaca taatttttta tttcatctcc
    18061 atcattctcc cagttaacca cgtattcatt gtttccatac cattttctaa aacgaccacc
    18121 tttagttgta ggaaaccatt tttttctaga ctttttagcg tcctctaatg ttttagcatc
    18181 aaactttatt ttgttaaatt ctacttcaaa ccaataccgc aaaaatttat tgttatttcc
    18241 ggttgccaac ccttgttttg catctgcaac atcgttagtt aattttcctt gagcaaaatc
    18301 agtgattacg ttatcgcttg cccagtaagc aatcggcatt cctgggattt ttttgaagtt
    18361 gtcttgatta gtactataaa aataatcgca ttcaccatgc tgatgaattg cttctaacgt
    18421 tttaattttt tgaacttcca ttccaccttt aaaatctgat aattttatat agcttccatc
    18481 ttgttcattt gaatttttta tcgtaaacgt acaaattgga acggttgctt cttcaaaagc
    18541 tgaatactcc atttgaatca aactagaaat gtttctttca ttaattaaaa atgagcgtaa
    18601 cttttcatag ctagaaatga acatccaaac aaatggcgtc ataaaggaag catatccatt
    18661 atcaatcagc atttggctat tcaatttaat aaacacagaa aatagatctt ttttgacatc
    18721 agaatagtta tcatttacat atttttttaa tttcttatcc attttattaa gataaggcgg
    18781 attagtgact accgctacat atttatcaac tagcatttca gccacgtcaa gaatgtgcaa
    18841 gtatttttct tgtatttcct tcatcccata aagaatatcc atattcgtaa attcgttgaa
    18901 ttttgatata tactctctta cttttcctaa gtattcttta gttattgcct gattattttt
    18961 atcgactaac ttaatgattg atccaagttc tttcccattt tcaaattgat caaaaattaa
    19021 ctctttgtat tcattccagc gttcactata cttatcattg ttcaattcac taatacgctc
    19081 ttgatactcg tctgtcactt taggagaatc aataaactct cttaaattcg gcgatagact
    19141 ttttttcaaa aaaagacgat cgtattgacg ccctttcatc ataattgcaa aataagacaa
    19201 ttgatacgct cttttatcga tttcaagacc atataaattg tattcaacga ttgcacgtgc
    19261 agcatcacgc tcagaatatc ctaacgtaag ataaatttcc atcaatacat cgaaggcgta
    19321 aactaaaata tgcccagacc ccattgcgtt atcgataatt tttagttctt ctggttttaa
    19381 attacttaca gatgttgctt gttcaaaagc atatttatct ggaattaagt atttcaactt
    19441 atttcttaat tcactattgg gataatgatc taaccaatac tttcctaaac tattgtcaac
    19501 catataacga acgacccaat ctgtggtaaa tagttgagtt gctgccggaa tatcttgttt
    19561 tttgacaatc cctttataaa tattcaccac ttgattatgt ggctcactat tatagtactg
    19621 atacaaccac ccaataatct ctacctgtcc accagcttga acatagaaat catcctctgg
    19681 aatacttaaa agatcagcga ttacaccatc ttttttaata taagaagctg taaacaaaag
    19741 ttctgtataa tcttctactt cttcaaatag ctcaggtaag taatcattca attgattaca
    19801 gatttttata aaaatcaatt gatacagctt gtccattgct tctgctgaat tatctgtttt
    19861 ccaagttctg acttgttgct gttcattact agataattct tcaaagatat cggcatcata
    19921 aatatctgta ataatatctg gctcaatttt cccacttatt tcactagata atacacgata
    19981 cgtgtcaggt aaataatcat ttacctccat aaaccgaatg gcaatcaatc ggttaaacca
    20041 cgtataagca acctcttcga ttaactcttg aaaagcttct gaataagaag tgacagaagc
    20101 acgttgtttt agttctgcaa tcaatttgtt tctttgcgct atttcttttc cttgaattct
    20161 tattcctgat ttttcgattt cttgtaaatt gctatcaatt ttcttcacat cttcaatttt
    20221 tgattcatca attcctaaac gttttgcttt agtcattact tcatcaatta attttctacg
    20281 ggcattgacc gcgaaattct ttatcgcttt cttatccatt tttctttccc ttctatatgt
    20341 aacctttgaa aagacaggca cctttttatg cctgtctttt cactagaatt gaatcgtgat
    20401 ttctgtattt tcttgaagtt gttccttcag tttttgatta atttcagctg ttaactcatc
    20461 aatatctgct gctgacttaa tagttttaac atgaacgtta agtgttctca ttggtactgt
    20521 tttctgttga atagtaggtt ttactatcgc tatttcttca gcttttgctg cagagtctat
    20581 ttcatctttt tcagtttcac gaatcaagtt tgctgcttca atttgtttac gtgcttgttc
    20641 ttcttgacgt ctgcggtttt cttcattatc gaaacgttga ttaaagatca aatactgttc
    20701 tgctacgttt aatgataaga aaacaagatc atctatagta ttcgcttgtt caatttttgc
    20761 tttcagttct tgaaattctt ggtcaactat tggtacaaat tgatccttaa aatcttttcc
    20821 ttctaataat ttaaatgttg cttgtttttc ttccgttaat ttatttaata tttcctgact
    20881 ttccaactct aacagttgat tatattgttc aataaattct tgaatcaact catttagttt
    20941 catcatatct gaataaggat cagccttttt caaaatggtt ttcatctcat gaatcaattg
    21001 atcaatttct tggctagaag tttgacgccg acttttttcg attaatctaa ttttatcttg
    21061 tgcattctcc cagatttttt tctgagtact attttgcttg tggaaatttt taattttatc
    21121 atatgtttca gcccagtcga ataattcatc gcgatatttt ttgattgtat aaaaaaagtc
    21181 ttcaacatct gacgtttgaa caattacttc aagatatttt tttatttgct catattcata
    21241 agcactaggg taggtataag tgttttgtaa atcaaaataa gagcgtaaat tgtctaattg
    21301 accttttaaa tatttcttga aattttccat tgtatgttca ttgttatttt catcaacaat
    21361 attacgactt tgaaacagtt ctctaccgat ttcgtcaacc aatttttttg cttttggcga
    21421 aatcaccgcg cttggttcaa tttttatctt ttcactttct cgtcgttttt gaataatcat
    21481 tacaatacta tttggatcat ccatccgtga aatttgtaca ttgttataaa gtaaatcaat
    21541 tttaccagac atgaaaagtt tagcgatgca ccattccaca tcaagttctg tgaatccata
    21601 cggttgtttt gtttcaaaac gatcacgaat tgttttcatc gtaatcgtta ggtgatttct
    21661 cttttgatca ttgataaaat tgaaaatttc ctgaactgct tgctcatttg atggatcttc
    21721 aataatttca tttttgcttt ctttcactaa atataagata tcttcttttt ctttaggcgc
    21781 atcaatttgg tttaatttat ggtatacttc ttcagccatt ttctgaagtg ctgattggaa
    21841 ttttgcttta aagtcggagc ctgtcagttg aatttctgca ccgttataga aaaattttgc
    21901 agatttcaac agttcattta attgatcgtt gatacttgca cttagttcct gtaattcacc
    21961 agatttttcc gaacgaatcg cgtcaaagtt ctttactaca ctcgaataag tcgttgttaa
    22021 ataaagattc attctagcat acattgctat atcatcttta aattctttat ctgatggcaa
    22081 ttctacgaat aataagttac gggaactctt aagcgcaagt tctgcctctt gacctgctaa
    22141 atcagagtat ggtgaaataa aattaactgt catttcagca tttccagctt gcttgtatgg
    22201 acgttgatct aacacttgtg cataagtaaa cgtataccgg tttttaaatt tatttccacc
    22261 tgacatgcct aatttttcat aggcaaaact atttcggtct agaacgccgt caaaaattcg
    22321 tttagatagt tctacgatca aatcactatc tgtaatattt tgatttttaa tctcacgagt
    22381 aatttcctgt tcttcatcag tttggaaaat ataactatct aagttcttcc gcacaaagtt
    22441 ttccttaatt aaaaggtcca atgcttcttc tactcgtttt ttagtttcca ggcggtcttc
    22501 gttgatattt cttatcatca agctcgtaat attttcaaca tttggtttga tggcttgatc
    22561 aacatattta atcatgaata aaattcgtaa gacatttacg ttaaagttat ctatatcagt
    22621 tggtctttga atatgagaat tatttgtagc ttgtgtaatc actcggctaa ttgctgtatc
    22681 aatccaacgt tctaacgagt aataaaactg atctaaagaa accaaactgg ttgtatcatt
    22741 ttccttattt cgttcagcgg cttctttaaa cattgctagt aatgaacgtt caccagacga
    22801 taagtttgat ccttgatagc tgtgattacg aatctcggtt agaatttgcc ccaataaatt
    22861 gaattgatag ggaataaatg gataaacttc tgcgtaattt tcagcatctt ggaagagctt
    22921 taattcagga ctatcaacaa agagtaattt atttttcaat tctgtttgaa cagtttcaaa
    22981 ttgtaaggct aaagaatcat tggcaaactc ttttttcttc aaaatacgtt ctttaattac
    23041 ttcatcggca tttgctgaag ataaactcac agttgtggca aaacgatcct tgatcttaga
    23101 aaaatcatta tcagaattgt tatcaaagtt tgttacgtga tcaatcgctt cctgacttgt
    23161 cactaatacc caagccttac cttcacaaat tcgacccaaa tcttccacaa cggtttgtaa
    23221 ctgcaaagtc aactcacgat taccgccgat atattgtccg acctcatcga ctagaaaggc
    23281 aatatgatgg tctgcttctt tggaatcaag atagctttta actagatttg caaagtcatc
    23341 aatgcttatt aaataatttc ctgatgcttt ttctaaaaaa ttatcaatag cggcttcact
    23401 cataaaatcg attttaagtg ccgcttcttt gatatcatct tggatccaat caaactcatg
    23461 gcgctcttct tgccattttg ccccattaat ctcttcaaaa gcagctttga atgcatcaaa
    23521 cttttcttct ttaattaacc gacgttcaaa atctgctaga tgtggaatcg tgcttaatcc
    23581 ttgcatttcg ttaaatacct ttaaaaaaac attcacgatt ccgtttttgt cttttttacc
    23641 acctgcatca ctttttgaat caatattaaa cagaataaca tctgtattta tttgtgagca
    23701 ccgttccatc gttgccaaag tcagtggatc tttgattttc ccatcttctt tgaagtaatc
    23761 aatggctttc ttgtcattta tttctcgatt tgcgagcaag taagaaataa tttttaagaa
    23821 atgagattta cctgaaccaa agaacccctg aatccaaaca cccattttat ctgttggtgt
    23881 attgatactc cgttggtagg catcaaaaat tgttttaaag tgtttttgta gttctttcgt
    23941 aaccacgtat tcttctaatt cttgttgaac attttcatcc tttgcttgac cgaccttaat
    24001 aactccttga atatttcggt caattggttt tgcaaaaata tctttaatta gcatttaatc
    24061 tcctaccttc catcccaact aaattctaaa tgctcgataa taattatcat ctttattggt
    24121 attaagaatt gtcaaactta attcatcata ttcccctgga tacatcatca caactggtac
    24181 gcgatcaaat acctgatgca ttttatttaa aatagagtgc gctctaatta atggatataa
    24241 ttcgccaatt cctgtcagga acacaactga tttttctggt gtatgggcat ccacatattc
    24301 aaaaaataca ttttcttcct caggtaaatc cattttcaat aaacgaccaa tgctttccac
    24361 taatttttgt aaaccacgtc gttcttccat cttaatcgct ttttcagtga aaccgcgttt
    24421 ttctagatac tctaacataa tcacatagag attataaact ttcacttcat aattatcacc
    24481 aacagatgtt ccagatatat cattaatata atctcttaca attaactcgt ctttcggatc
    24541 gtagtcaaag atataatagc ctacttcatt acctaaacca cgattcaata aaaaatcttc
    24601 tttttgaatt acttcattca acttttccaa atgctcttga atcgataatg acattataaa
    24661 attcctccca gtgctagtac aatatcttta cgattcttgt caactaacca ttgaatcaat
    24721 cgtttatcta ataatatcgg agtcattcgt ccatattctt tttcccctct gactaatcct
    24781 gtttcaatta gattcgtttg ataagcggca ataagccgtt taatcgtata atctttccat
    24841 tttgaaatat cttctgaact tctccgcttc tctgtaaaaa aagaacggta atcaactggt
    24901 gttaattgca aatttccttt acgtagattt tcagcatata cctcagtcat aaattcatta
    24961 aaaagatcat caatcataag gatggaaatc aaattcacta acttttgatt atctatattt
    25021 aactgattga aaagttgcaa tccagcttca tccagttgac taactctcct tttcacgttc
    25081 tgatagattt ctttttgacg gttactgctc actgcaaaaa aaatattttc atgttcattt
    25141 ttctctttaa tttctatatc tgtatatcct tctagtcgta attgaatata taacttgaac
    25201 tctgaaaacc aaaagcgttt agaaactaga ccagcagaat attttttatt caatagattg
    25261 cctcctaatc atctataatt caataagtaa acaagtgttt tttgctcatc gttagcattc
    25321 attttttagt atctactata caatacatat ttattatag
//
LOCUS       DACGEU010000037        25266 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.037, whole genome shotgun sequence.
ACCESSION   DACGEU010000037 DACGEU010000000
VERSION     DACGEU010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25266)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25266)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25266
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.037"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(79..333)
                     /locus_tag="IXR40_001417"
     CDS             complement(79..333)
                     /locus_tag="IXR40_001417"
                     /inference="COORDINATES: protein motif:HMM:NF013677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAQ4361274.1"
                     /translation="MTRYEENFKQMIVELNQTGRSVRGLAKEYGLSEATIYKWKNLYL
                     PDQSTGLTGKEVAELRKENARLNEELEILKKAAAIFSRKT"
     gene            complement(737..1519)
                     /locus_tag="IXR40_001418"
     CDS             complement(737..1519)
                     /locus_tag="IXR40_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361275.1"
                     /translation="MENSSNSAEVNVSTSTSEVVKCSQETTSLPEELLGDWQINNKDA
                     GIEISDSKAVFRIGRSQVESKDYYVDVNNKMLLHVYFSFEYDSVKYIEVSIERTGYSE
                     FISKSVGILTMHTKDGQYISLGVKRVSGENNETEAVTEQTMDERIDSSKSNETEVDTG
                     KTIDERIDSFIETYTAIPPTWKLVNEDKGITINTDTEISTDAQSLSDLLANLTGISNA
                     VTEQVGKDIPLRLLENGKKDYSVVFKNGQVTDYNEVFKKVIE"
     gene            complement(1584..2420)
                     /locus_tag="IXR40_001419"
     CDS             complement(1584..2420)
                     /locus_tag="IXR40_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAQ4361276.1"
                     /translation="MRVIKTLNNSLILCLDKQGKEVILMGKGIGFQLKKGDLVPADKI
                     QKVFKLDSLSDALKKDYIKLFEAAPDDLIICVKRIIDYANAKFDFKLNKSLFFTLVDH
                     LKHAIERSQKGIVFQNRLLIEIQKYYPKEFEIGCYAIQLINKKMNVQLPEEEAGNIAF
                     HIVNAQSEQANMEETMLSVRALKDILAMLGYLFPEKKVDKDSMLYLRFVTHLQFFIAR
                     MIKKEELPEKDDFLLASVKQRFPKEYRAALKIKEYVQEEMGASANQDELLYLTLHISR
                     VY"
     gene            complement(2438..3847)
                     /locus_tag="IXR40_001420"
     CDS             complement(2438..3847)
                     /locus_tag="IXR40_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010757186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAQ4361277.1"
                     /translation="MQYKQLSAFPEKFLWGASISAYQAEGAYQEDGKQPSIIDKYQHT
                     EGVANFEVASDFYHHYKEDIQLFKELGLKAFRFSIAWTRIMDIENNKTNQKGISFYHQ
                     VIDECLNQGIEPIVTMYHFDLPYFLEEQGGWLNRATIDYFVDYVQVLLTEYGDKVNYW
                     LTINEQNTMILHPGAIGLPPSGELPSKKELFQINHHVLLAQARVIHLYHQLNLKGKIG
                     PAINLTAMYQATSSPEDAIAAHNWETLRGWSFLDVAVRGKYNYLFENYLNDRGLYPKI
                     EAEDQAILSSGKPDFIAINYYSTATIAASKNDGSDVSARAGDQQIMLGEEGVYRAAEN
                     PYVDKTPYGWVVDPTGLRLTLRKLYDRYDLPILITENGYGAPDIVEEDRRINDQDRID
                     YLAKHILAIQAALTDGVDVFGYLPWSAIDVVSTHQGFNKRYGFIYVDRTDENLKELKR
                     IKKESFFWYQKVIARNGLA"
     gene            complement(3861..5684)
                     /locus_tag="IXR40_001421"
     CDS             complement(3861..5684)
                     /locus_tag="IXR40_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4361278.1"
                     /translation="MDYREVGRNVLQQVGGKENVVSLTHCATRLRFELKDKRKADTKA
                     LEKTLGVISVVDSGGQYQVVIGNEVQTAFKEIQKEVGTSIKKGPSSDNQESIISRLIS
                     VISTTFTPMIPAITGAGMVKAILAVLTLTGVLSDSSQTYIILNTIADAAFYFMPVLLA
                     YGAAIKFDVNPILAITVAGILLHPNISQLFSTGDAVSFLGIPVLAADYAGSVLPIIFT
                     VWIMSYVEPFADRISPSFIKFFTKPMLVFLIMGPLALVVIGPFGTLLNDLIAMGAEWI
                     NGKAAWLIPFLMGGLQPFLVVTGTAWAMTPIATMQLSSTGSEMINGPGMLASNIAQSG
                     ATFAVAAKTKNKELKQLAVSTGITALMGITEPSLYGVTLKLKKPLVASMIGGAIAGLY
                     AGLSGLVRYAFVSPGLAALPAFIGENPMNIVHAIITCVIAFVATFIIAYLIGFDDTSD
                     ESEQTAIAEAVIVENPVKGTVCPISEVNDAVFSKGLLGKGVAIHPEENSIYSPVEGEV
                     ITILESKHAIGLRSKEGIELLIHVGIDTVNLKGEPFEVFVKAGDQVSAGQLLINADFA
                     AIRNAGYDDTVIVVVTNSENYAGISEASGSLKEHEPLMQIS"
     gene            complement(6527..6853)
                     /locus_tag="IXR40_001422"
     CDS             complement(6527..6853)
                     /locus_tag="IXR40_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361279.1"
                     /translation="MNKVNMNKKFIIIVIVVLAIIGIIFSKMTGTSGLEKSSKPLVTQ
                     ILQEQYNLNRSCDDVTITHENGDNTYRAKAILDNGSAININIEYYPKKDRIYVEIPYA
                     EVLMLN"
     gene            complement(6899..7261)
                     /locus_tag="IXR40_001423"
     CDS             complement(6899..7261)
                     /locus_tag="IXR40_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010717431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-ribbon domain-containing protein"
                     /protein_id="HAQ4361280.1"
                     /translation="MYCRKCGKEITDESKYCQFCGALQETDETTGADAVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVALAFIPVVFGAVAVIMGYLYRDKDEQMGTILM
                     IAGVAGAIFGVLLGMSMY"
     gene            complement(7298..7512)
                     /locus_tag="IXR40_001424"
                     /pseudo
     CDS             complement(7298..7512)
                     /locus_tag="IXR40_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            7640..7975
                     /locus_tag="IXR40_001425"
     CDS             7640..7975
                     /locus_tag="IXR40_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4361281.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAEKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVVVDYEEEFLALYRSLSTEDAVRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            complement(8051..10048)
                     /locus_tag="IXR40_001426"
     CDS             complement(8051..10048)
                     /locus_tag="IXR40_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361282.1"
                     /translation="METSMINIPIYVDKEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSIEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSFYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFNHKRSNVYRLDVFNATSVIQKLNEDILPLLEKFHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELTNTVC
                     ERLRNVGNNSVENALKENRGYFVKQGFTLERASKDIKRLYNVKASSSFLVYLAKGAGI
                     DEVIKELILSGVELVPLYQFTSVTRDDGRRVRKRKDPIVLN"
     gene            complement(10146..10421)
                     /locus_tag="IXR40_001427"
     CDS             complement(10146..10421)
                     /locus_tag="IXR40_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4361283.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            10653..11387
                     /locus_tag="IXR40_001428"
     CDS             10653..11387
                     /locus_tag="IXR40_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4361284.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIVEEFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            11426..12568
                     /locus_tag="IXR40_001429"
     CDS             11426..12568
                     /locus_tag="IXR40_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAQ4361285.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(12663..14054)
                     /gene="sufB"
                     /locus_tag="IXR40_001430"
     CDS             complement(12663..14054)
                     /gene="sufB"
                     /locus_tag="IXR40_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HAQ4361286.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(14059..14529)
                     /locus_tag="IXR40_001431"
     CDS             complement(14059..14529)
                     /locus_tag="IXR40_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HAQ4361287.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            complement(14516..15751)
                     /locus_tag="IXR40_001432"
     CDS             complement(14516..15751)
                     /locus_tag="IXR40_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HAQ4361288.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            complement(15748..17034)
                     /gene="sufD"
                     /locus_tag="IXR40_001433"
     CDS             complement(15748..17034)
                     /gene="sufD"
                     /locus_tag="IXR40_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HAQ4361289.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            complement(17047..17820)
                     /gene="sufC"
                     /locus_tag="IXR40_001434"
     CDS             complement(17047..17820)
                     /gene="sufC"
                     /locus_tag="IXR40_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HAQ4361290.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            complement(18017..18865)
                     /locus_tag="IXR40_001435"
     CDS             complement(18017..18865)
                     /locus_tag="IXR40_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAQ4361291.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            complement(18889..19575)
                     /locus_tag="IXR40_001436"
     CDS             complement(18889..19575)
                     /locus_tag="IXR40_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4361292.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            complement(19568..20602)
                     /locus_tag="IXR40_001437"
     CDS             complement(19568..20602)
                     /locus_tag="IXR40_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAQ4361293.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     gene            complement(20997..21335)
                     /locus_tag="IXR40_001438"
     CDS             complement(20997..21335)
                     /locus_tag="IXR40_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HAQ4361294.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     gene            complement(21337..21693)
                     /locus_tag="IXR40_001439"
     CDS             complement(21337..21693)
                     /locus_tag="IXR40_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HAQ4361295.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            complement(21699..22886)
                     /locus_tag="IXR40_001440"
     CDS             complement(21699..22886)
                     /locus_tag="IXR40_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HAQ4361296.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            complement(23077..23922)
                     /locus_tag="IXR40_001441"
     CDS             complement(23077..23922)
                     /locus_tag="IXR40_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAQ4361297.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            24156..25121
                     /locus_tag="IXR40_001442"
     CDS             24156..25121
                     /locus_tag="IXR40_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HAQ4361298.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
BASE COUNT         7389 a         5310 c         4282 g         8285 t
ORIGIN      
        1 tagggatttc taataaccga cataacaaag aaacagtgta atccttacac catttttcaa
       61 taaattgaac aagcgaattt aggttttccg agagaatatg gctgcggctt tttttaagat
      121 ttcaagttcc tcatttaaac gagcattttc ttttctcagt tcagctactt cttttccagt
      181 cagtcctgtg gactgatcag gtaaatataa attcttccat ttgtaaatcg ttgcttcaga
      241 taagccatat tctttcgcta accctcgaac agaacgtcca gtttgattca gttcaacaat
      301 catttgttta aaattttctt catatcgggt cataaaaatt catcctctcg tagataagtt
      361 taatttattc ttgtctctac gaaaagctgt ctaagatttg atactaacac caagttatct
      421 ttagaaccat ttcagataca tatgaaacaa ttacatatga ttttttcata aaaaaacagt
      481 actgtctagt agtataaaat atacaaattt cttaaaaatt ttttcactaa aatcactacc
      541 tgaaacagtc taaaacactt atatatcaac gtttaatgaa actatctccg tttcatttca
      601 gatacaaata aatatagtcg ggctccaaat ccgaaaaaaa atacccccag tagcttatcc
      661 taagctactg gagatgtata agtacggtca tataacaacg gggtagggta aataaatgaa
      721 aaagatggaa gaatcattat tcaataactt ttttaaatac ttcgttgtaa tcagttacct
      781 gtccgttctt aaataccaca gaataatctt ttttcccatt ttcaagtaac cgaagtggaa
      841 tgtctttacc aacttgctct gtcactgcat tactgatacc tgttagatta gctaataaat
      901 ctgataaaga ttgagcatct gtagaaatct ctgtatcagt atttatcgtg attcctttat
      961 cttcatttac aagcttccaa gtaggtggta tagctgtgta tgtttcgatg aatgaatcaa
     1021 ttctttcatc tatcgtcttc ccagtatcta cttctgtctc attactctta gatgaatcga
     1081 ttctttcatc catcgtctgc tccgtaactg cttctgtctc attattctca ccggaaactc
     1141 tcttcacacc caaacttata tattgtccat ctttagtgtg catagttaaa attcccacgc
     1201 ttttactaat aaattcacta taaccagttc tttcaataga gacttcaatg tatttcacac
     1261 tatcatactc aaaagaaaaa tagacatgta aaagcatttt gttgtttaca tctacataat
     1321 aatcctttga ctctacttga gaccttccta tacggaatac agctttactg tctgatatct
     1381 ctataccagc atccttatta ttaatctgcc aatctccaag tagctcttct ggcaagctag
     1441 tagtttcttg tgaacacttt accacttcac tggtagaggt cgaaacattc acctccgcac
     1501 tgttagaaga attttccaag gaatcaggag ccttagcaca accaacaagt ctttatatat
     1561 tgtgcagccg atattttctt cattcagtac acccttgaaa tatgcagtgt tagataaagc
     1621 agttcgtcct gatttgctga ggcacccatc tcttcttgaa cgtactcctt gattttcaag
     1681 gccgcccgat actctttcgg aaaacgctgc ttcactgaag ccagcaaaaa atcatccttc
     1741 tccggcaact cttccttctt aatcattcgg gcaataaaaa actgtaaatg cgtcacaaat
     1801 cttaagtaaa gcatcgaatc tttatcaacc tttttttcgg gaaacagata tcctagcata
     1861 gccaagatat cctttagtgc tcttaccgag agcatggttt cttccatatt tgcttgttca
     1921 ctttgggcat ttacaatgtg aaacgcaatg tttccagcct cctcttctgg caactgaaca
     1981 ttcatttttt tgttgatcaa ttggatagca tagcagccga tctcaaattc ttttgggtaa
     2041 tacttttgaa tttcaatcag caggcgattt tgaaaaacaa tgcctttttg actgcgttca
     2101 atggcatgct tcaagtgatc aaccaaggta aaaaatagac ttttattcag cttaaagtca
     2161 aacttggcgt tggcataatc gataattcgc ttgacgcaaa taattagatc atccggagca
     2221 gcctcaaaca gtttaatgta atcctttttt agagcatcag aaagtgaatc taatttaaat
     2281 actttttgga ttttgtcagc cggaaccaaa tcgcctttct ttagttgaaa tccaatccct
     2341 ttccccatca aaattacttc tttgccttgc ttatctaagc aaagaattaa actgttgttt
     2401 aacgttttaa ttactctcat tagattcacc gttctctcta agctaagcca tttcttgcga
     2461 ttactttttg ataccaaaag aagctttctt tttttattcg ttttaattct ttaagattct
     2521 catcggttcg gtcaacatat ataaaaccat aacgcttatt gaagccttga tgggtactaa
     2581 caacatcaat cgctgaccaa ggtaaataac caaaaacatc tacaccatct gttaaagctg
     2641 cttgaatagc cagaatatgt ttggctagat aatcaattcg atcctggtca ttaattcgtc
     2701 tatcttcctc aactatgtcg ggtgccccat agccattttc agtaattaaa ataggtaaat
     2761 catagcgatc gtacaatttc ctcaatgtta atcgtagtcc agtagggtca actacccagc
     2821 catatggcgt tttatctaca taaggatttt cagctgcccg gtagacacct tcttctccca
     2881 acatgatctg ttgatccccc gctctagcgg aaacatctga tccgtcattt ttgctggcag
     2941 cgatggtggc agttgaataa taattaatcg caataaaatc gggtttaccg gaggataaaa
     3001 ttgcctgatc ctctgcctca attttaggat ataatccacg atcattcaaa tagttttcaa
     3061 acaaataatt gtattttccc cgaactgcta catctaagaa agaccagcct ctcaatgttt
     3121 cccaattatg ggctgcaatt gcatcttctg gactggaggt agcttgatac atagccgtta
     3181 aattgattgc tggaccgatt tttcctttaa gattcaactg atgatacaag tgaattactc
     3241 tagcttgagc taataaaaca tggtgattaa tttgaaagag ttcttttttt gaaggcagct
     3301 ctccacttgg tggcaaacca atcgctccag gatgaaggat catcgtgttt tgctcattaa
     3361 ttgtcagcca atagttcacc ttgtcaccat actcagtaag caatacctgt acatagtcca
     3421 caaaataatc gatagttgct cgatttaacc aaccgccctg ctcctctaga aaataaggta
     3481 aatcgaaatg gtacatggtg acaatcggtt cgattccctg attcaggcat tcatcaatta
     3541 cttgatgata aaaagaaatt cccttttgat tggttttatt attttcaata tccataattc
     3601 gcgtccaagc gatggaaaag cgaaaagctt ttaagcctaa ttctttaaac agctgtatat
     3661 cttctttata gtgatggtaa aaatccgagg caacttcaaa attagctacc ccttctgtat
     3721 gctgatactt gtcaataata gacggttgtt tcccatcctc ctgataggca ccctctgcct
     3781 ggtaggcact aatggaggca ccccataaaa acttctctgg aaatgctgaa agctgtttgt
     3841 attgcacaaa aatcctctcc ttaactaatt tgcatcaatg gttcgtgttc ctttaagctt
     3901 ccgcttgctt cactaattcc tgcgtaattt tcactgttgg tcactaccac aatcactgta
     3961 tcatcgtagc cagcgtttct aatggcagcg aaatcggcgt tgattaataa ttgtcctgct
     4021 gacacctgat ctcctgcttt tacaaatact tcaaagggtt ccccttttaa attcacggtg
     4081 tcgatcccca catggatcaa taattcaata ccttctttag aacgtagacc aatcgcatgt
     4141 ttagattcta aaatagtaat gacttctccc tcaacaggtg aataaatgct gttttcttct
     4201 ggatgaatgg ctacgccctt tcccaatagt cccttagaaa agacagcatc gttcacttca
     4261 gaaataggac acacggttcc ttttaccgga ttttcaacaa tgactgcttc ggctattgcc
     4321 gtttgctctg attcatcaga agtatcgtca aatccaatta gataagcaat gataaaggtt
     4381 gcaacaaagg cgattacaca cgtaataatt gcgtgaacaa tattcattgg attttctcca
     4441 ataaaggctg gtaaggctgc taagccaggg gaaacaaagg catatctgac taaaccgctc
     4501 aagccagcat acaaaccagc aattgcacca ccaatcatgg aagcaactaa tggttttttc
     4561 agcttcaagg ttactccata gagtgaaggc tcagtaattc ccattaaagc agtgatccca
     4621 gtggacacag ctagctgctt caactctttg tttttagttt tcgcggctac agcaaaggta
     4681 gcacctgatt gagcaatatt agaagccagc attcctggcc cattgatcat ttcagaaccc
     4741 gtactgctca attgcatagt agcgattggc gtcattgccc aagctgtacc cgtaaccacc
     4801 aaaaatggct gcaaaccacc catcaaaaat ggaattaacc aagctgcttt gccgttaatc
     4861 cattcagccc ccattgctat aagatcgttc agcaacgttc caaacggtcc aatgacaacc
     4921 aacgctaaag gccccataat taaaaatacc agcatcggct tagtaaagaa tttaataaac
     4981 gaaggcgaaa ttcgatccgc aaagggctct acataggaca tgatccaaac agtaaagata
     5041 atcggtaaaa ctgatcccgc ataatctgca gctaataccg gaattcctag aaaagaaacg
     5101 gcatcgccag tagaaaaaag ctgtgaaata tttggatgaa gcaaaatgcc agcaacagta
     5161 atcgccaaaa ttgggttgac atcaaacttt atggctgccc cataggctaa tagtactggc
     5221 ataaaataaa aggctgcatc agcaatagta ttcaaaatga tgtaagtttg actactgtct
     5281 gatagtacac cagtcaaagt caagacggcc aaaatggctt ttaccatccc ggcacctgtt
     5341 atagctggaa tcatcggtgt aaaggtggta gaaatgacac taatcaatct tgaaataata
     5401 ctttcttgat tgtctgaaga ggggcccttt ttaattgaag ttcccacttc cttttgaatt
     5461 tccttgaagg ctgtttggac ttcattgcca atcaccactt ggtattgtcc accgctatcc
     5521 accacactaa ttacaccaag tgttttttct aaggctttcg tatcggcttt ccttttatct
     5581 ttgagttcaa aacgcagtct ggtggcacaa tgggttaagc tgaccacatt ttcttttccc
     5641 ccaacctgtt gcaatacatt tcttcctact tctctgtaat ccattattct ctctccttaa
     5701 agcagtaaaa aagaccaagt caaaccacgc cccaatcaac attgaagtgt tagtttgtct
     5761 tggtcttgcc tgcataatca gtaacatgcc aataacgtta ttttgctgta atccaataat
     5821 agcacattat gatagcgcaa tcaacaggga atttaatttt ttatcttttc gtttgaccgt
     5881 atagggtaat ataacagtta gatcacatca actagggtat atctgcgtat acttactgct
     5941 aaaataagta tatctaatat taactatacc agtaaaacca ttcctacata accagcggga
     6001 aattcccaaa atcgtgaaag catcaaaaat gcatataacg gatcacacaa cttcaacaat
     6061 tctgctcttg ggaaaaattg atgaatttgg tgagtaaagg atggaataaa cagcattcca
     6121 acaatatagg caacaatagt gatacttgtt tttttggtaa aaatcagtaa gcaatagcca
     6181 atttcaatca ttccgagata taaaggtatc gatagaatga tttgggctag tattcttaaa
     6241 aattaactag caaatgttta aactgattta tttctaatct acatgtagta agtatttcaa
     6301 ttccaccaat tatcaataaa aataccaaac atatccataa taattttttc tttttcattt
     6361 cttttatatt gttataacag tgaataacat aaaaattccc gacaatcatt gtaatatttt
     6421 tttgtcacct gtattagtat ttaatttata ggaaactata aaaactccct agtgaattta
     6481 cacctttggg agttcctgtt tggacggtat gcataataca tttaaatcaa tttaacatta
     6541 acacctcagc atatggtatc tccacatata tacggtcttt ctttggatag tactcaatat
     6601 ttatgttgat agcacttcca ttgtctaata tagctttagc ccggtatgtg ttatctccat
     6661 tttcatgagt aatcgtcaca tcatcacatg atcgatttaa gttgtactgt tcttgtaaaa
     6721 tctgtgttac caatggtttc gatgacttct ctaatccaga tgtacctgtc atttttgaaa
     6781 aaatgatacc tataatagcc aagacaacga taactataat gataaacttc ttgttcatat
     6841 ttactttatt caacttttta tctcctatct ccaaaataat ttgctcttat ccctcttatc
     6901 agtacattga catccctaaa agtacaccaa agattgctcc agctacccct gctatcatca
     6961 aaatcgtacc catttgttca tctttatctc gatataagta gcccataata acagcaacag
     7021 caccaaatac aacaggaata aatgctaacg ctactaccat agaaatccaa ccaataatca
     7081 aatacagctt ccctgtctct tgtccatgta cgatttgttc cttcatttca ttaattgtct
     7141 gctcagtact tttctttact gcgtctgctc cagttgtctc atctgtttct tgtagtgctc
     7201 cgcaaaactg gcaatactta ctttcatctg ttatttcttt gccacatttt ctacaataca
     7261 tgtcttctcc tcctaaaaac attcaattgt ttattagtta actgtttact ttattaaata
     7321 catcagaaaa cagctcattc attggtacac ttaatatctc agaaagcatc ttcatttgat
     7381 agggtttagg aatcgttctc cctgtttgcc acgaacttac acattgctgt gtaacattca
     7441 tttttttgct aactccgttt gagaaagtcc tttttctttt ctgtatcggc tgagattact
     7501 tacttttttc atgattctcc cctcctgttt tattatatac aacaatacga tgtatttcaa
     7561 ctcataaaat ataaaaaaac ttcaaatacc attacaaata caacaacttg ttgtactata
     7621 ctgagatggg ggtgtattaa tgaaacagaa acaatatgca aaggtcatta gagaaaagcg
     7681 aaaagctctc gggtggacac aaaaagaatt agctgaaaaa atcttctcta cacaacaggc
     7741 agtagcaaga tgggaaaatt ctgtaacaga gcctaacctc gatagcttaa ccgctctttc
     7801 tagagcccta ggaacccctg taagccattt tctagacaat gttgtcgtag attatgagga
     7861 agagtttttg gctctctatc gttctcttag cactgaagat gcagttcgaa caattgacta
     7921 tatgaagcta ttaaaaaggc aagaaaatga acgcaatcag ctattgaaag attgaaaaat
     7981 aaataaccca ccgaacttta acggtgggtg tattgagatg aaataagatt aagagctatg
     8041 gataacctgt ctagtttaat acaattgggt cttttctctt ccttactctc cgtccatcat
     8101 ctcttgttac acttgtaaat tgataaagag gaactaattc aactcctgat aatatcaatt
     8161 cttttattac ttcatctatc cctgctcctt ttgctaggta gactaaaaaa ctactacttg
     8221 ctttcacatt gtatagtctc ttaatatcct tagaagctcg ttcaagagtg aatccttgtt
     8281 taacaaagta gcctctgttt tcttttaaag cattttccac gctgttattc ccaacattac
     8341 gtagacgttc acaaacagtg ttagtaagtt ctttctctgt cattagatat gttccttgcc
     8401 acgataagcc ctgtaaaact tcatgtgctt catctaaaat caattgtttt tccttgctaa
     8461 gttctgatcg ggaattttga ggaaatactc ttttagcctc tttttcgtta aaacatatct
     8521 taacccattc ataagaaaaa tattgatatg taaaatgaaa tttttccaga agtggaagga
     8581 tatcttcatt caatttttga atcacagaag ttgcattaaa aacgtctaat cgatagacat
     8641 tgcttctctt atgattaaag tttcctaacg ctttctcttc ctttaaccta tttaggtatt
     8701 cgagcatctt caaaggaaca tcttcatcat ctaatttttt tatcaatcct ataaaagtca
     8761 taagtgatag taacttatta catttatcta tgtcataagt tttaccatag taaaaactca
     8821 tttttttagc taattgttcc cccgacaaaa tacaagtcac actttcctta ctatcatcaa
     8881 aaaaattaac atcagaaagc aagacatcat agacacgtcg catttcctct agataattcc
     8941 ttattgtcct gaaaagtttg tctttcattg attcaagagt gtcaaaaagt acttttgatt
     9001 cctctttcaa ttttcgaaaa tgtgtaggat acaagtctag gttctctaat agccaattaa
     9061 atgtttctac ccgactgtct ttctttaaaa ttagcatcac aactccaata aaattttcac
     9121 tgatatcaca attactggaa tgacaataaa aaatggaatg cccagtttta ctggtaaaaa
     9181 tactagcaga gggattatga tcgttgtgaa acagacatct taagttttta cttgacttaa
     9241 gtaatttatt catatcaatg gttaacaatc tttcataaat ctcattaaaa gacatgtcgg
     9301 aggaatcaaa caggcagtct ttaaaccact gtttcatttc ttctttgtcg tcatttttta
     9361 tcaacttaac aaaatcggtt tcattgacta gttcatactc tctccctgaa tcactttgac
     9421 aatttttaga acatgtcatg gtaaaatcaa tcggaagctc agtaatatct aacatgttgt
     9481 cttcattaat tattatcact gcatctgact tatatcctcc aaaaaacatt ctattcgaag
     9541 catttacatt gtcatcacac ccggggatgt tctttttcaa gtattcgtaa acagcaacca
     9601 ttttaccata gtcagtaatt gcttctttta atagaaagac aatcttgtat ttttctagat
     9661 tttcagagta ccgaatactt ttttgtatcg caaacgcaga attatgaact aaattgatag
     9721 ataaaacctt ttctatgctt aagtatctac tatcatcttt actcaaatct actaccttcc
     9781 ccttctcatc tttaacagtg ttatcgacat ccagaataat tactctggtt tccacaaaac
     9841 tctccttgtc attgccttta ttctttgtct tgcttggaat aaatgattgt gatgaattta
     9901 gtatctctac aaactcatct cttgtaactt ctctatagtt atctaaacac ctatctctta
     9961 catcagtttt ttcttttttt gtaactggct tctctaataa tttttcttta tctacataaa
    10021 ttggaatatt aatcattgat gtttccattt gtgtttcctc cttataaaat tctgttaaag
    10081 actaaaacat acagataata aaaacaaact ctttattact atatgtttta gtcttatttg
    10141 tttactcaac ctttataccg ttccatgaaa ctatcaatat cagatttttt aaatctaatg
    10201 accgtatcaa tttttataac aggtaacccg tattgagaaa catattttct aatcgttcct
    10261 actgatacac ctagatattc acttgcctgc tgatagtcca tatactctag agtgactcca
    10321 gaaataatgt cttctagcat aggctttagc actgtaatta tctctttcac ttgttgttca
    10381 acttgtatag aaacaatgct atcaatgatt tgtagagaca tatttccccc tcctttcgtg
    10441 attgcttgaa caaattttct aagaattatc ttcgtatttt ttgctcaaaa taaaagtatt
    10501 ttgttattaa ccgattaatc aaacaaaaaa tgattaccag ttcatcgaca tacacataat
    10561 acctcgataa aaaagaggtg tcaatatctt tgtaaaattt atttacaaca cccctttttc
    10621 gaggtatact aattttagga ggtgtggtca atatgataaa acgtccacca ataaattatt
    10681 tagaacgaaa aaagatactc ggaacaaaaa taaaagctat aagaaagagt aaaaaattaa
    10741 cacaaccagc atttggtctt atgattaaca acggtcaatt aattgacaaa aaaactatct
    10801 acgaatggga gaagggaacc tatttaccaa taccagagcg attatcccga attgctgatt
    10861 tgggaaatat gagtatagag gagttagttt gtggcaatgt agaagaatat attttgggaa
    10921 ttattcttta tagagatagc attgtactag atggtataac atttccagat aaaaacctgt
    10981 tccagcatct tcgtcaacag ttcccaccag tacactctaa tttagataca tggctggata
    11041 gatattccaa attagaacca gagatgcaag aatttattgc taacaagact tgtaataaag
    11101 ttaaaaatga aaaaattagt cttttcaata tcttaaaaat agaagaatta ttcatcaatg
    11161 ctattgtaga agaatttgac aataacattc ttttcctcac tagcagtata gaagaactac
    11221 tagaaagaat ggtagatgaa tggctaccta ttcaattgaa agacatgtct tatcccgaag
    11281 aagctgtgag agaaattact gataatataa acaagctaga acaaacgatt tcatcaattg
    11341 ggaaaaaata cactaagaaa aaaatgaagg gaggtgatac catctagtgg taagtactcc
    11401 ttgtaaacta agaggagatg atttcatggc aaaaatatca aagtacaaaa agaaaaacgg
    11461 tcaagtggcg tggatgtata aaggacacat tgccaccgat ccacgaactg gtgaaaaaat
    11521 aaatactacg agaagaggtt ttagtagcaa acaagaagct caaaaagatt atgacgagta
    11581 cagacatcaa atattatacg gtgttaaaaa gaaagcacct gatatgacat ttgaagacct
    11641 gtataatgaa tggataactc atcagcgtac cagtgttaaa gcttcaacaa tcgcaatctc
    11701 agtaagatac gcaaataatc aaatacttcc agcatttggt aagcttaaac tatcgaatat
    11761 ctctgtccca tattgtcaaa aagtggtaga tgaatggcac agtaaatatg aaagttacga
    11821 ttatatgaga aaacagactg cacaaatttt acgctacggg gttgcaatgc aatatattga
    11881 caataatcct atggaaaaaa cacttcttcc acgaaaaaaa gagtatgaga aaaatcgtaa
    11941 attttactca aaagaggagc ttaataattt actggatgct tttaaagatt ttggtaacat
    12001 gaaacaatac gccttcttca gattattggc atacacaggt atgagaaaga gtgaagtact
    12061 cgctttacag tggaaagaca tagacacgtt taataaagaa ctacatgtca ataaaactct
    12121 tgctgtagat gaatttggta aagttataat tcaatctccg aaaacaagag cttctagacg
    12181 agttatctct ttagatactg agactctttc tatcctcaac aactggaaat tacagcaaaa
    12241 agaagagtat ttaaaacttg gatacaatac tagctctaaa gagcaacatg tttttacaac
    12301 agttaaaaac actctataca ttccaaacac tgttaatgat tggttaagat atattttgaa
    12361 aaaatataac ttgcctcgta ttacacctca tgggtttaga catacacatg ctagtttatt
    12421 attagaagca ggagaatctg tcaaggtagt tcaacaacga ttagggcatg aaaatagtaa
    12481 agtgacatta gacatctatg cacatattac aaataatgca cctaagaaaa caggtcaaga
    12541 ctttgctgat atgatggctc atcagtaaaa gagctggtca aaatctggtc atttctagta
    12601 tacaggcaaa acaaaaaagc tagaaccctt atatatcaag ggttctagct cctataacag
    12661 gtttacccaa cactgccttc catctcataa ctgatcaatc gattgagttc gactgcatat
    12721 tccattggaa gttctttggt gaatggttca acaaagccca tgacgatcat ttcagttgct
    12781 tcagattcgg tcaggcctcg gctcatcaga tagtagagtt gttcttctga gatttttgag
    12841 actttggctt cgtgttctaa agagacttgg ctgttgtgga tctcattgaa tgggatcgta
    12901 tcggatttcg accattcgtc catgatgatc gtgtcacatt cgatatgaga gatcgaaccc
    12961 gcactgtttt tggcaaaggt tacttgtcct cgatagttta cttctccgcc gtcttttgaa
    13021 attgatttag agacgataga gctagatgta tttggtgcat tgtggatcat ttttgcaccc
    13081 gtatcttgga tttggtttgc tcctgcaaag gcgatggaga gcatggtgcc tcgtgcacct
    13141 tttccatcta agtaaacact tgggtatttc atcgttgttt ttgcacctag gtttccgtcg
    13201 atccattcaa cggttgcgcc ttcgtatgct tttgctcgtt tggttactaa gttgtacaca
    13261 ttgtctgacc agttttggat cgttgtgtaa cggcaatacg catcttttct tgtaaagatt
    13321 tctacgatgg cggcatgcag gctgttactt gaataagtag gtgccgtaca accttcgaca
    13381 tagtggatgc ttgctccttc gtcaacaatg atcagcgtac gttcgaattg ccccgtgttt
    13441 tccgcattga tccggaagta cgtttgtaat ggaacatcga ctttgacgcc ttttggcacg
    13501 taaataaagg tcccacctga ccatacggct gaattcagcg ctgctaattt gttgtcggtt
    13561 ggcggtacaa gttttgaaaa gtactctttg aataattcag ggtattcttt caaagcagag
    13621 tcagtgtcag taaagacgat tcctaacttt tcgaattcat ctttcatatt atggtacacg
    13681 acttctgatt catattgtgc ggaagcaccg gctagataag ctcgttcagc ttctggtata
    13741 ccaatctttt caaatgtatc tttgattttt tctggtacgt cttcccagtc acgagcgggt
    13801 ttgtcacttg gtttttggta atatttgatg gcatcgaaat cgatgtctga aaggtcgggg
    13861 ccccatgttt gcattggcat tttgttaaat gtttctagag atttcagacg gaattcaagc
    13921 atccattctg gttcgccttt gattcttgac atctcacgga tcacttcttc tgtcaagcct
    13981 tctcctgtac tgaaaaccgg ttcgacatca tcgtgaaacc cgaatttata ttcttctaat
    14041 tctggtacgc ccatgttctc actcctcttc cttgtggtaa tgatggaaag ctgcggtacc
    14101 atcgttttcc attgcttttc ctagtgcttt ccaggcaagt gtcgcacatt tgatccgagc
    14161 gggaaattta gctacaccac caagcatagc agcatcgcct aattggtcgg gatctttgac
    14221 ttcttttcct tggacaagct gtagaaagtc tacagttaaa tgttctgctt cttctattga
    14281 ttttccgatg acggcgtctg tcatcatcga ggcacttgcc gtactgatgg agcagccact
    14341 gccgtcaaag gcgatatttt tgatgattcc gtcttttaca tcgacttgca attcgatcac
    14401 atctccacat gtggggttgt tcaattcgat cttgcttgtc gagtcagtca agcttccacg
    14461 atgatgcgga tgggaagaat gatccaagat cacttgacgg tataaattgt ctaatttaga
    14521 tagtcccatg ttggaaaaac tcctttgttg ccatgattgc ttcaactaaa cggtcggcgt
    14581 cttgcgttgt gttgtagaaa taaaagctcg cgcgagcagt cgctgatact tcaaggtact
    14641 tcaatagcgg ttgcgcacaa tgatgacctg ctctgacggc taccccttcc atgtctaaag
    14701 ctgtcgcgac atcatgggga tgtaacccat ccaaattgaa tgcaacgact cctgtccgaa
    14761 aattcgggtc ttgtggacca taaacagtca atccatcaat tgcttgtaat tttggcaaca
    14821 cataagcggc tagttcttct tcatatcgat ggatattgtc cataccgagt ttttgcaaat
    14881 aatcgattgc atggcctaat gcgatagcgc cggcgatatt tggtgtccct gcttcgaatt
    14941 tccaaggtag ttctttccat gtactgtcgt ataattcgac aaaatcgatc atttcgccac
    15001 caaattcaac aggttccatt tcttctaacc attttcgttt accatataaa acaccaatac
    15061 ctgttggtcc gcacattttg tgtccgctga aagcaaagaa atcacagtct agtgcttgga
    15121 catcaatggc catgtgcggg gcagattgag caccatctac tacgatgacc ccgccgtttt
    15181 catggacaag ttcagctaat tcttgaacag gattgaagac acctaagaca ttggatacat
    15241 gagcaatgga gacgattttg gttttgtccg taatcttttt cgctgcatcc tccatatcca
    15301 ggaagccttc ttctgttagt tcgatatatt tcaagacagc acctgttcgt tttgccaact
    15361 gctgccacgg gataacatta gaatgatgtt ccatgtaaga gagcactatc tcgtctcctg
    15421 ctttgatata gcggtcgccg aaggttctgg ctacccaatt caagcttgtc gtcgtaccac
    15481 gagtaaacag cacttctgct gtttcttttg catggatgaa cgcccgtact ttttctcttg
    15541 cttgttcata atcatgggtc gcgcgttctg ctaacgtatg gacaccgcga tgaacattgg
    15601 cgttatcgtg ttcgtaatag tacgctaatg cctggagtac ttgttttggc ttttgggtcg
    15661 tcgctgcatt atccagataa actaaaggtt catcattgac gtcttgaaat aagataggaa
    15721 aatcattgcg tagcttttta gcatcgatca tccattcaac ttcccttcga ttacttcgac
    15781 taattctttc cgaacttgtt ctacagggat tgctgttaag acagaaccga ggaatcctcg
    15841 aatcactaag cgctctgctt cttctttatg caatcctcta ctcatcagat agtacatttc
    15901 ttctggatca actcgtccta cactggcagc atgtccagca gttacttcgt tttcatcgat
    15961 caaaagaata ggattcgcat caccacgtgc tttatcagaa agcatcaaga cacgactttc
    16021 ttgttgggca tctgcacctt ttgccccttt caagatgtgg ccgataccat taaaggtcaa
    16081 tgttcctttt tctcggatca ctccgtgttg caaaatatgc ccgatcgtat gaggggcttt
    16141 attggttact cgtgtatcga ttccttggat ttgtctgccc gagctgattg ccacgatttt
    16201 gacttctgcg tgtgcacctt ctcctgctaa atctgagtca aagtcagcga tcacatgacc
    16261 gtcattcatg acaccaattg cccagtcgac agaagcatct cgtaaaatgt gcccacggcg
    16321 attcatataa gaagtaatat tttctcctaa ttgatctacg gctgaatatt tgatttttga
    16381 accagcttta gcgatgactt ccacgatgat attacctgat gattttgcta cttgttcttt
    16441 ggttgtctgg aaacgttcca gataagaaaa ttcactatgt tcatctgcca cgatcaacac
    16501 atgcttgaag aagtgctcat cggatgcgcc atcttgaatg aataaggact cgagtggttc
    16561 atcgatcacg acatttttag gcacatacag gaaaataccg ctgttcataa aagctacatg
    16621 gagtgcagtc aattggtctt cgttcatgtt tactgctttt ttcatataat attcttggac
    16681 tagttctgga tattcgatca ttgcagtgaa caagtcggta aaaatgactc ctttttctgc
    16741 taattccaca ggcagttgtt caaaaatcgt ccatgaacct tgttggacaa gcacaggatt
    16801 gtctttcatt gcatcaaatg ccggaatcgt gcctgtttca ctgatggttt gtgtttcttt
    16861 cacatcaaat aacgaccagc gatggaattt cacccgatcg atatgcggca atggcagttc
    16921 atctgctttc gctagtgcgt cttgacggaa ggttctcatc caatcaggtt cgcctttact
    16981 taaagaaaaa tcatttaccg cgtcaagata atcgagccag tttttttctt tcattcttgc
    17041 tcccccttac gcttcttctt ctttatagtc gattcctaat tctttactga taccagcgta
    17101 gccttctgct tccagacgtt tagctaggtc agcattccct gtcatgacta ctcggccttc
    17161 catcatgatg tgaacgacat caggtgtgat atagttcaat aatcgttgat agtgggtgat
    17221 gatcaatgca ccgaaattgt ctccgcgcat ttcatttact cctttagcaa cgactttcaa
    17281 agcatcgata tccagacctg aatcgatttc gtctaaaatt gcaaatgtag gttctaacat
    17341 caacaattgc aggatctcat tccgtttctt ttctccgcca gaaaaacctt cgttcagata
    17401 acgttcagcc atttcttctg gcatatttag taaagccatt ttttcatcta actttttcaa
    17461 aaatgccata acagaaattt tgtcgttttc atcacgtttc gcattgatcg ctgcacgcat
    17521 gaattccgca ttcgtgatac ctggtatctc acttggatat tgcatagcta aaaataagcc
    17581 aagtcgcgca cgttcatcta cttccaagtc taaaacattt ttcccgtcaa acaaaatttc
    17641 gccttctgtt acttcatagt ttggattgcc catgatagcg gcagataagg tagattttcc
    17701 tgtgccgtta ggtcccatga tggcatggat ttctccggtt ttcattgtta ggtttacgcc
    17761 tttaaggatt tctttttcct cgatcgacac atgtagattt tttatttcta agacagacat
    17821 gcattatacc cccaaattct ctttcgttct cactcatttt agactaattg agaatgaagc
    17881 gcaatgacct tccttactaa aatcaaatat cttttattta ttattaaaca attttgattt
    17941 ctaaattaga ataggtataa aaaagatgag aaataagcca ttacagactt atttctcatc
    18001 ttttttgttc cataccttat tttgcatcag cctttactgg tttaacagag ccgccccatt
    18061 tgtctgtgat ccattcttgg acttctttgc ggtgaagcac ttcaatcagt tttttgattt
    18121 tgtcactgtc ttcatcacct ttacgagtcg caataatatt cacgtaagga gagttgtcct
    18181 tttcaagcaa tacggcatct tctaatggat tcaaccctgc gccgtaagcg aagtttgcgt
    18241 tgattgcaac taggtcacct tcatcatttt ggtacgtaga agctaaaagt gatgggtcga
    18301 tcgtatggtt gaacttcaag ttcttagggt tttcttcaat atcatcgaat gttgctgttt
    18361 ccagatctac tccatctttg actttgacta agccagcatc ttgtagaatt gtgatgatgc
    18421 gtccccagtc tgattcagaa tttgaagtaa tgattgttgc accatctttt aattcggaaa
    18481 catctttgac ttttttagag tacaagccca ttggttcgat gtggacagca ccggcattga
    18541 caaagtcata tcctttttct ttgatttctt tgttcaaata aggaatatgc tggaagtaat
    18601 tggcatcaat gtcgccttct tccaaagatt ggttcggtaa tacatagtca tcgaatttga
    18661 cgatttcaag atcgattcct tcatctttca ataatggttt cacatgttcc aaaatctctg
    18721 cgtgcggtgt cggtgaagcg ccgactttca atgtcgtgtc gtctgcttta tttgctgaat
    18781 ctttgctgtc gctgttgtta ccgcatgctg ctaatcctac agtcagcaaa agcgctgctg
    18841 caaatccaaa aattttcttt ttcatatcct acatccccct atatcctatt atcttttgtc
    18901 tgttttctta gttaagaaat caccgattcc ttgaacgata aatacgatta gtaaaataat
    18961 taaagtcgca acgaatgtca ctgttagatt accacgctgg tagccttcct gccaagcaag
    19021 acctccaagt ccacctgcgc cgatcgcgcc ggccatcgca gtaaatccga tcatcgagat
    19081 cgttgtaact gttaatccag aaatcaatgc gggaatactt tcaggtatca agaccttcca
    19141 gatgatttcc cagtaacttg ctcccattgc atctgctgct tccagtacac cagggctgac
    19201 ttcacgaaaa gcaatctcta ctagacgggc ataaaatggt gctgcggata aaacaagagc
    19261 tggaatggct gcttgcgcac ctagcatagt gcctacgatt gctttagtaa atggaatgat
    19321 caaaaccatc aggatcataa atggcgttga ccggaaaata ttactgatga tcgatacgat
    19381 tccataaatg attcgagcat acggtttgtt tttgcgtcca atagagtaaa ggatcaatcc
    19441 caaaactaat ccgatgatcg tcactaagac cattgagatt aatgtcatat atagtgtatc
    19501 aaggatagcc tgattcatcg tttccgggtt gatttgttta aaatctagat atgtttctga
    19561 aaagctttta tccacgatgg atcacctcaa ttcctactcc ttgttctttg atgaacactt
    19621 ctgcttgatc taattctttg gtttcaccag tcatcaagac agtcaatgaa ccaaaggaac
    19681 cttctttcac ttgtttgatc tttccataca caacgttgac atcgatgtta tagcgtcgaa
    19741 tcgcttggga aatgactggc tcgttggcat ttctttcgct aaaggtcaaa gttgccaaac
    19801 ggccgcttgg attttctttg atgagttcag ctaatagttc tgtcgaatca gcttctggtt
    19861 cgatgtcttg ttgtacaaag cgtttggtta cttctttttt cggttgtctg aagacagtca
    19921 atacgtctcc ttcttctacg actttcccca actccatcac agcgactttg ttgcagattt
    19981 tgcggatcac attcatttca tgtgtgatca agacgatggt caaattcaat ttcttattga
    20041 tcgctaacaa taagtctaat acttcttctg ttgtttgcgg gtccaatgcg ctagtagcct
    20101 catcacaaag caggatctca ggatcatttg ccaatgctcg tgcgataccg acgcgttgtt
    20161 tctgtccgcc ggaaagttgt gaaggatatg cttgtccgcg tccttctaac ccgactaaac
    20221 gcaacagttc ttctgcccgt tctttacgtt tgctctttgg tacgccagct aattccagcg
    20281 gcagctggat attttcaagt acagttcttg accataacag gttgaaatgc tggaagatca
    20341 taccgatttt ctttcggaat gtacgtaatt ctttgttttt taattttgta atatcttgat
    20401 cgtttacgat cacttcgccg ctcgtgggaa gctcaagtcc attcaggaga cggactaatg
    20461 tactttttcc tgcgccagaa tagccgacga ttccataaat atcccctttt tcaacgttta
    20521 gtgaaacgtc attgacggct tggatgtttc cgtttttccc attgaatgtc tttttgacat
    20581 tcgttagttg gattaatgac atgccattca catctttctc ttataatttt tcaaacaaaa
    20641 aagccttcgc cctcttgcct taagcaaaag gacgaaagct tgaacttccg tgttaccacc
    20701 ttgatttacc gttacttcgc aataacagcc tcttccagta cttggactta gcttctttcc
    20761 gtatactgtc gcgctgtaac gggcactccc gtagtaagtt tgcttacgct cgcttactct
    20821 gctctaagac catcttccat ctcattttcg ttacccattt tcagcaaaca gggctctctt
    20881 caaacgtccg tgacatgtac tcttcttttc aaagctttct cgtttcatat aggattgctt
    20941 atgattatag caactggaag aatcagtgtc aacttttttc aagtgatttt ctgattttat
    21001 aattcgtcaa attcttttgg atcaacatct ttgaaactta agatccacgc attcatttca
    21061 tctgaatcat tcaagatatt gatatcttca ccgattttat cattaacaga agaaactgta
    21121 cccgttagcg ggctggcaaa ttcattgacc gctttttccg cttcaacttc gatcagaggt
    21181 tcatcttttt ttagcgattg tcctgctttt ggcagattgg caaacgtgat gtctccaagt
    21241 tcttcttgcg cttcatttgt caaaccaaca cagtattctt ttccattaaa taagatccaa
    21301 aggttgtcct ttttcttcaa atgcttgcct gccattttat atcagttctc cttcataaat
    21361 tttttcattg aatccaattg caacaagctg gtcctctcgt aagatcagtg gtcgcttgat
    21421 cagcatacca tctgtcgata agacttggct cgcttttgaa gccgtaaact cgcctacttg
    21481 atctttcagt ccaagttccc gatatttcat cccgcttgtg ttgaacaggc gacggattgg
    21541 tacttgactc gtttctagcc aagtctcaat cgttgaggcc ttcggtactt ctttgatcat
    21601 atcaacggtt tgataactaa cgccatgctg gtctaaccac gctttggctt ttttgcatgt
    21661 tgaacatttc gggtaccagt aaaaggtgta caattttctt acctccttga agatcttgca
    21721 ggtgcttcat tttggtatct catcgataat atcaacccga taccgatcat gttccctaaa
    21781 atcgaggatc ctccctgact aatgaaaggc aatgggatcc ctgttaaagg aagtaatccg
    21841 atatttgctc caatattctc aaagacatgg aacagcagca tcatgatcaa accgcttgcg
    21901 atataggcgt aaaattcatt attcgtatcg aaacacaccc gaatcatacg atagattaaa
    21961 ataaaataca agaaaatgac gaatgcacca ccgataaagc cgaagttttc accgataacg
    22021 gtaaaaatca tatcggactc acgaacaggc acatagatat tgcttacgtt gaatccttta
    22081 ccaaacaagc caccggtacc aattgccaaa agtccttggg ccggctgata actcattcct
    22141 gacgtatcat ggaaagggtc cagccatgaa tcaatacgtg caaactgata agatttgaat
    22201 ccaactttat aaagcaagtc tcttccgcct tcagtcgtaa ccaagaagat cgttcctgct
    22261 ccaacgacta ctgccaagat tactacaggt gcgatgatgc gccaagagat tccagacatc
    22321 aggaaaatcc cgccaaagat cgcaagaaag acaagcatcg ttccaaagtc atcttgggcc
    22381 atgatcaatg ctaaaaccgg tattgtcacg atcaagagct tcccaatcag ccaaaagtcc
    22441 gatttcatcg tccgttcttt tacttgcgta ttatgtttag ttacgatcag tgccatcatc
    22501 aagatgtacg caatcttcat caactctgct ggctggaaag taaacgcacc gaatcgaaac
    22561 cagtttttag accctgttga agcagctaaa ttctgatcat agaatttgag caagagtccc
    22621 attaccacta accccaaacc ataaaggtaa ggagtcagtt tccagatcca tttggaattc
    22681 aaatgcatga tgacaacgat tgctgccgct ccaactaaat accagacaac ttgcatccct
    22741 acgcctttca agactgctgg attgttcgga tcatggctaa gtgctacata taatgagagc
    22801 agaccaatca aacataacag aaagactggt aaaatcacgc cataatcaat acgattatcg
    22861 ttcgaagctt ttaatttttt ttccatgttt catccctttt cttaaaaacc atactgctga
    22921 ttattatagc ggtccagtta gataatggaa agtctttcca tagacatttg ggaaaaatta
    22981 actttccgtt tgtgcagttg cttgagcaaa tgcagtacaa aagcctactg cttatcttta
    23041 gtgtatcata gaactttttt tgatacatgc aattatctac cagctgagat tctcctcgct
    23101 gtgagaagtt tctgtgcttt cattgtatcg aaggatctct tcggcaatct ctagcagctg
    23161 atcagaaacc agattggttc gttggatgaa ataaaaatat cgatggaaat tcaacggagt
    23221 cattggcaca ttttctggaa cagagcgctt agacaaaatc gagcgaccga ttccttcctt
    23281 cagcaacgca acaattacat cgttactttt cacgatcatc ttcttatctt ggatattcat
    23341 ctcttcaaaa taacgctgcg tgtaatgaaa aacaccagag tttgcttctc ttacaagcca
    23401 caatttgctt tttgggtccc cagcgatgac tagctggtct tccatcaaag agtatctttg
    23461 tacgccggaa gtctctaatg gcttttcgat aaaaccaaaa tcggattcat gtttcgctac
    23521 ttgttctaat gattcatgag aattcgtgat ttcgatctca aaatgcactt taggaaacct
    23581 tttgatcaga tgtttcatca actgaggcaa aagatagaca gcaaaggtgt gggaagcaac
    23641 gatccgacat acttcttctt cattttgttc attgagcaat ttttgctgag tttcttccca
    23701 ttcttctaac aaaaccagtg tccgttcata taataagtcg gcttgcttag ttggaagcat
    23761 ctcttttctt ccgttacgtt gaaaaagatc gatattcaat tcccgctcca actgtttgat
    23821 ttgattcgag actgctggtt gagataaaaa cagtacttct gctgctctgg aaaaatttct
    23881 tgtttcatat actgctcgaa aagtcgttaa taacttaaac atggcaccac ttccataact
    23941 ttttatgata attactataa aaactatttg atttaaatat acaaaaaacc atctataata
    24001 gaaatgtaca acaaaacagt tgctgatcca actagtaact tagatgaaga caatcagctg
    24061 tctgcttgct cgtaatcata cattcctatt cattttacaa tgtattcgtt catcttggta
    24121 ctaaaatcta ttaaataaaa aggagaatat tatatatgaa gaactttttg aaaattattc
    24181 cgatcccgat ctgcgggttg atccttgggt tagcttccct tggaaatctg tttaaagact
    24241 atcaccatgt tgctttaggc aatctaactg gcggtatctc tatgattctt atgatattca
    24301 tttttgttaa attgtttatc ttattcgaac acacgaaaca aacgttgcat gatccaatca
    24361 tcgcctccgt ttcaccaact tttacgatgt cactcatggt tatttgtact tattttgttt
    24421 catatgaaag tattgcacca attgtcaaat tcatttggct gtgcgctgtt atcttccaag
    24481 tgatccttgt cttttatttc aattatcacc atgttatcaa agctgatctt tcaattgaag
    24541 caatttatcc aagctggttt atcatttacg ttggatttgg ggtcatcact gtaactgccg
    24601 ggaacttctt cccacttatt ggaaaaattt tcttttggat ttcattgatc tgctatgcgt
    24661 tcttattgcc gatcatcatc aaacgtgtct ttttcgtaag aaatatggct catccgacac
    24721 gtccgctgat tacgatcgtt gcagcacctg gttctctttg cctaacaggt tatcttaaaa
    24781 actttgctga acctaatttt tatcttgtcg tagcattgtt cgctttatct caagtattgt
    24841 atttcgttgt gctgtctatg cttccacgtt tgttcaagct tcgtttttat ccaagctatg
    24901 cagcctttac attcccgctt gttatctctg caacagctat atttactact gttcattact
    24961 tcaacagttt aggtatctat agtagcgtat tggatttctt aaaagttgcg gaatgtctgt
    25021 ttgcaagtgt agttgtcttc tacgttcttg ctcattacgt acgtttctta attaaagaac
    25081 atagcaaaca tggaaaattt gtttctaaaa aaatcgctta ataatcgatt caataggttg
    25141 tgaaaaagct gttctgcatc aagtaataag aacggccaaa caaaaacagc tgttcatgtt
    25201 tttgtactgg ttgggcttat taccgcagat gcaagctttt gaacaccgtt taccaagagg
    25261 tcgtaa
//
LOCUS       DACGEU010000038        23828 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.038, whole genome shotgun sequence.
ACCESSION   DACGEU010000038 DACGEU010000000
VERSION     DACGEU010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23828)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23828)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23828
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.038"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(53..787)
                     /locus_tag="IXR40_001443"
     CDS             complement(53..787)
                     /locus_tag="IXR40_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HAQ4361299.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1114..1524
                     /locus_tag="IXR40_001444"
     CDS             1114..1524
                     /locus_tag="IXR40_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HAQ4361300.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1517..2218
                     /locus_tag="IXR40_001445"
     CDS             1517..2218
                     /locus_tag="IXR40_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HAQ4361301.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2218..3804
                     /locus_tag="IXR40_001446"
     CDS             2218..3804
                     /locus_tag="IXR40_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAQ4361302.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3823..4044
                     /locus_tag="IXR40_001447"
     CDS             3823..4044
                     /locus_tag="IXR40_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HAQ4361303.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4041..4802
                     /locus_tag="IXR40_001448"
     CDS             4041..4802
                     /locus_tag="IXR40_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HAQ4361304.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            5182..5691
                     /locus_tag="IXR40_001449"
     CDS             5182..5691
                     /locus_tag="IXR40_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HAQ4361305.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5766..6305)
                     /locus_tag="IXR40_001450"
     CDS             complement(5766..6305)
                     /locus_tag="IXR40_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HAQ4361306.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(6445..7056)
                     /gene="rpsD"
                     /locus_tag="IXR40_001451"
     CDS             complement(6445..7056)
                     /gene="rpsD"
                     /locus_tag="IXR40_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HAQ4361307.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            7372..8169
                     /locus_tag="IXR40_001452"
     CDS             7372..8169
                     /locus_tag="IXR40_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate-nitrite transporter"
                     /protein_id="HAQ4361308.1"
                     /translation="MNPVSPLFEKIDASIEKKANLFENSFSRYAVRAVLACLFLTLGT
                     AVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAELGTSNMLYMTVGVFRQRLA
                     LSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNFMLESIAVKLAKPSATILV
                     EGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLGYEHVIANFPAFTLTYFAS
                     HGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQSKSSYVD"
     gene            8197..8832
                     /locus_tag="IXR40_001453"
     CDS             8197..8832
                     /locus_tag="IXR40_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HAQ4361309.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            8852..9625
                     /locus_tag="IXR40_001454"
     CDS             8852..9625
                     /locus_tag="IXR40_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAQ4361310.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            10033..10830
                     /locus_tag="IXR40_001455"
     CDS             10033..10830
                     /locus_tag="IXR40_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HAQ4361311.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            10808..11221
                     /locus_tag="IXR40_001456"
     CDS             10808..11221
                     /locus_tag="IXR40_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361312.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            11205..13850
                     /gene="mutS"
                     /locus_tag="IXR40_001457"
     CDS             11205..13850
                     /gene="mutS"
                     /locus_tag="IXR40_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HAQ4361313.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            13868..15976
                     /gene="mutL"
                     /locus_tag="IXR40_001458"
     CDS             13868..15976
                     /gene="mutL"
                     /locus_tag="IXR40_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HAQ4361314.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRQTGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            15998..16558
                     /locus_tag="IXR40_001459"
     CDS             15998..16558
                     /locus_tag="IXR40_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HAQ4361315.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(16643..18631)
                     /gene="treP"
                     /locus_tag="IXR40_001460"
     CDS             complement(16643..18631)
                     /gene="treP"
                     /locus_tag="IXR40_001460"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HAQ4361316.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            18854..19567
                     /gene="treR"
                     /locus_tag="IXR40_001461"
     CDS             18854..19567
                     /gene="treR"
                     /locus_tag="IXR40_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HAQ4361317.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            19644..20090
                     /gene="msrB"
                     /locus_tag="IXR40_001462"
     CDS             19644..20090
                     /gene="msrB"
                     /locus_tag="IXR40_001462"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HAQ4361318.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            20260..20862
                     /gene="ruvA"
                     /locus_tag="IXR40_001463"
     CDS             20260..20862
                     /gene="ruvA"
                     /locus_tag="IXR40_001463"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HAQ4361319.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            20875..21876
                     /gene="ruvB"
                     /locus_tag="IXR40_001464"
     CDS             20875..21876
                     /gene="ruvB"
                     /locus_tag="IXR40_001464"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HAQ4361320.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            21905..22483
                     /locus_tag="IXR40_001465"
     CDS             21905..22483
                     /locus_tag="IXR40_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HAQ4361321.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            22535..23017
                     /locus_tag="IXR40_001466"
     CDS             22535..23017
                     /locus_tag="IXR40_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HAQ4361322.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            23134..23508
                     /locus_tag="IXR40_001467"
     CDS             23134..23508
                     /locus_tag="IXR40_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361323.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
BASE COUNT         7781 a         4287 c         5115 g         6645 t
ORIGIN      
        1 aaaaaaactt ggtacgcaat cgctgtacca agttttttta tttagctttt gattaagcca
       61 taaataataa tttatataag aatactgcta cgacaccagc acagataggt gctacaactg
      121 gtacccatgc atatccccat tgagaagaac ctttatgttt caatggaaga agtgcgtgta
      181 caagacgtgg agcaaagtcg cgggctgggt ttagtccagg acctgtagga ccaccaagtg
      241 aagcaactaa tgtccataca aggaaaccaa gtgctaagtg agctgtacca agattatctt
      301 ggaagaatgg tgcttttgta atacctaggg caccaaagaa taaaacgaat gaaccaaaga
      361 attcattgac gaaaccattg aatttagaac caacgctgtt gattgttgag aatgtaccta
      421 acacatggtt tacgtcttct gtttggtcgt agtaaggttt gtaacaagct actacgatca
      481 attgtccaat cgctgcacca atcaattgtg caatgatata aggaacaact tcagcccaag
      541 ggaatagacc attagatgct aaagcaattg taaatgctgg gttgatgtgg ttaccgctga
      601 ttccaccaaa aatcattgct ggcatcataa ccccgaatcc atacccgaca gcaatcagca
      661 tccagtcact gccatatcct tttgtacctt ttaaatctac gtttgctaca gcaccgttac
      721 ctagaacgat tagtaatgct gtaccaatca tttccgccgc aagacgggtc attagtgagt
      781 aatccataaa tacctccaaa agttataaaa atgcaaaaaa aaaagaaaca tcaacacgaa
      841 aagcatcggt gcagtgtttc gtgtcggaag gatttctgca gtcttaacaa atgtgaataa
      901 aaaaatgaat tccattactt ataagaaacc agaccaacag taaaactcca actcttttta
      961 aaagttctcc acaaatcacc aagcttaact ataaatatac caaaaaaaaa acgttttttt
     1021 tctcaaaaat tgtatcttag aaacagcatg ttttgaaact ttcagaaaag gtttgttagt
     1081 aaaatgaaag ctatacgtaa ggagtgttgt ttgatgaaat tttttcaaga gtttttcatt
     1141 attattttct tttctgtatt aggagaaggc atacggattt ttgctcattt acctattcct
     1201 ggaagtatct taggtattct ttttttattt ttagcatttg aaatgcatct tgttgatcct
     1261 gaaaaaatcg gagcaactgg tgatttttta ttgaataatc tagccatttt atttgttcct
     1321 gctggtgtag gtttattgga atattttgat gatattgctt cgatatggcc tgttttactg
     1381 ggagcagtcg tcgtgtgttc catcgtcacg atggttgcag cgggaaaaac ggcagaaggt
     1441 gtagaagctt tgctgggcta tgtccgtaag aaaaaagcag aaagggtatc tgtaaacgaa
     1501 atggaggaga atcaaattga ctgagttttt tgtgaatcca ttatttggct taagtttgac
     1561 tttaggagtg tacgtattat ctgacaaatt tttgcggaaa tataaactgc ctgttttgaa
     1621 tcctctcgta ttatcgattg ttgttattat cttatttttg catttttctg ggatcagcta
     1681 taaagactat aatatcgggg gcaatttttt gactatgctg attactcctg cgacagtggc
     1741 acttgccatc cctctttata aaaacttccg tttactgaaa gagaattttt atcctgtaat
     1801 ggctgcgatt ttagcaggaa tagtcgcaaa ttgcttggtt agtgtagggt tcggttactt
     1861 cttctctctt cataaagaga tggtgatctc attactacct aaatctgtaa cgacggctat
     1921 ttctgtcgat ttatctcata cgatgggcgg ggtgaatgcc gtgacacttg ctattgttgt
     1981 ctctacaggt atttttggtt cgctgatcgc cactcatatt ttccgcctat tcaagatcga
     2041 aagtccagtt gctcgcggtg tggcgttagg aagtacttct catgctattg gtacagcaaa
     2101 agcaatcgag attggtgaaa tagaaggaat catttccgga cttgcgatat gcgtcaacgg
     2161 aatattgacc gttttattgc taccgttatt ctttcagcct tttgctggct tgttttgatg
     2221 cgaaaaccac tattttatgc tacaataacc aaaacgttcg agcataaaaa aggagggaaa
     2281 gacgtgtatt tgtcttccga gtatcttaaa caatttgata aagatctata ttataagatt
     2341 ctcctcctag aaagttttga ggatcaagct tggcataccg ctgcacaatt agcgcaagtt
     2401 gttcagctgg atgcccgcag cgtgtcgaaa tacctgaacg agctgtctaa aaactatcag
     2461 cagtttagcg gtaagacaca ccctttgttt acaaaaaatc accgttctgg ttataacttt
     2521 tatgatacgc tcgattcaat tgaacatgag cgttttttga tctatctcgt gcaaagtacg
     2581 ctgaaattcc agttgctgca cgacattttt tttgaagaat tccatacaat gtaccaattt
     2641 gcgcaaaagc attacattag tgaatctact gctcatcgaa aaatcaatga atggaaacag
     2701 caactgcaaa cttacggaat tcggctgcaa cgaggtacat atatcgctca aggcgaagaa
     2761 gaaatcattc gactttactt gcatatgaca ttctggcagt tgtttcgagg gaaaatctgg
     2821 ccatttgaaa cgatttctca aatggacgta aagaatatgg cagaacatat catggctttt
     2881 tttaatgttc gtctgaacga gatcaaaaaa agacgattgg aatatatgct aggtgccttt
     2941 tttttaagaa aatcacagaa gcattatgtt gtattgaatg agaaaaaaag acggctgatt
     3001 tctgacaatc tgttgttcca gcgattttgc caggtcatgg agccggtatt tcctaattat
     3061 tttcaagtag aagacgagtt aggcgcatta tttcttgtac tgatgactcg tgaagaatat
     3121 tatagtgatc ctaagatacg gaagaaaatt tttgattttc atcaacaagc aaaaacaccg
     3181 ccctttacag ccctttcaga agcaaaagcc gctctttctc tttatcagga agagcagggg
     3241 ctgccagcag aaaatctaac cttcgaggca gaaaactatt tattcagcag tcattttttc
     3301 gcctatcttt ttcctaatgc gaaagaaacg attgatggca atagtagtga ttttattaat
     3361 catttagtta ttgaaaacaa ggaattgaaa caatggctcg tacatttttt tgaaagtaga
     3421 cacaaacatc ccaatcatct ggcatttaaa aatcatgcgt ttttgatggg gcggtatctg
     3481 actgtgttta aaacattagg agcctttact ccacagcttc caaagatcac gatcctttta
     3541 atgacagatt tcccattatt tgaagagcaa ctgttagagg agggattacg gacatttttc
     3601 cgtaatgagt atcagctgat ttttctgcca acagattatc gggggagaga agttgatctt
     3661 ctgatttcga caagtaaagt ccaccgcaaa ccatgggcgg atcttgacta ttttattgtg
     3721 actgaagaac taaaattaat tgattacatc caactatctc aaaaatttga aatgattcaa
     3781 aaacaaaaac tattaaaaca ataacaaaga aggagaaaaa agatgacatt tgaagaaatt
     3841 ttaccagaat tgaaaaaagg tgcaaagatt attcgtaaag gatggagtgg atttgaactt
     3901 tatgttgttc tcgtatccga tgatgaattt gatggctgtc cggtgacgcc gtacttattg
     3961 atcaaaacaa gtgacgaagg tttttccagc ttcgctccta cagtttgtga tattttagca
     4021 gatgattggg cgatcgtaga atgaaaaacc agtatccaga tctagctaaa caggttgtat
     4081 ttatcacagg agctgcttct ggaattggtg ctgcgcaagc ccgagcgttt cttgaacaag
     4141 atgcttttgt atttggatta gatcaaaagt tcggtaaaat ggaagaaatt tctttgcgat
     4201 ttcctgaaac ttttgcctac gcactaggtg atgttcgaca aatgaaagaa ctccaacaag
     4261 cggtatcgaa atgccaaaat cattttggtg aagttacgat tttactgaat acagcgggga
     4321 tattggatgc ctacaaaccc ttgatggaaa ctgacgaatc gctgtgggat ctgatttatg
     4381 agacgaatgt gaaaagcatg tatcagctga caaaaatcat ccttcctgat atgatccgcc
     4441 aaaaaagcgg aacgatcatc aatatggctt cgattgctgg cttgattgct ggtggaggtg
     4501 ggatcgctta tacaagcgcg aaacatgcga ttgtcggatt taccaaacaa ctcgctctgg
     4561 attacgcagg acagggtatc cgagtaaaag gaattgctcc aggagccatc caaacaccaa
     4621 tgaatgcggc tgattttgaa gggaaaggtg agatggcaga gtgggtggca aatgaaacac
     4681 cagtcaagcg atgggcacag ccggaagaag tagctgagct gacgttattt cttgcctctc
     4741 ctcaagcaag ctacatacaa ggaacgatca tcccaatcga cggcggatgg ttgttaaaat
     4801 aaccttgtgt ttttttcaag cttctgtatg ataaaactaa agagagaaac aacggttgat
     4861 gataaaaaaa gtcgatgact gttcccgaca ttcgatgccg aacagccagt tcaaaaaatt
     4921 ctttttaata atcgttaata ttcgaaacta agcggctttt cacgacctct tgatataaac
     4981 gatattcaaa agcttgcaac tgcggtaaca agtccagcca aatgaaaaat ataaggagct
     5041 atttttattt gaccattctt attacttgtt gcagggcagc tttttcacta ccttctgcga
     5101 cacttcagtt ggaattttct tcccatcctt tggtcgcggt cattaccaag ataaaattat
     5161 cttgcaaagg agaaatagaa catggaaaaa aataataccc gttcagccaa acgctggaca
     5221 acgacagatg tgactcggat ggcgctagtc actggtttat atgtggcagt gacgctggtt
     5281 ttgtctgtct ttagctttgg agtgattcag attcgtctct cggagatgtt caactatctg
     5341 tccttgtata acaaaagata catcgtcgcg gtaacagcgg gagtagcttt ggctaatatt
     5401 gcttctcctc ttggactgat agatgttgca gtaggaagcg tcagcacgct gcttgtattg
     5461 cttatcaact ataaaatcac tagtcgcatc aaaaacatga aaatcaaaat ggccgtgaca
     5521 gcatgcgtat ttgctttttc catgtttaca gtagctggtc agctaacgat tttatatcaa
     5581 ctaccttttt tcttgaattg gtgggtgatt gctttaggag aattggcatc aatgattgtc
     5641 ggtgggataa ttatttattg gatcggtaaa aaagtggatt tgtcaaaata aagatctgtt
     5701 taatttaaaa tagggcagca tggaagagac tgaatgttga gtcttcttcc atgctgcttt
     5761 tttgattaat ttgtatgaag aaatcgattt agccgttttt tcatcaagat accgatataa
     5821 gctgctccag ttgccttgat tgcttccggc agtaaaaacg gcagtagtcc actggcaaat
     5881 gcagttgtaa aagtaagatc accacttatt ttcagccaga tcgttccgca gatcaatgca
     5941 gcaagagagc ccattagatt ggcaaagatt gcatataagt aatgagcatc cgttctttcg
     6001 atcatccaac cagttatcca cgtttgtaag agaaatccaa tcaaatatcc gccagttggc
     6061 ccaaataaaa cagctatacc tccagtcatc cctgaaaata caggaagacc aatcaagcca
     6121 agtaaaagat aaactccaac agatatcaat cctagttttc ttccgagaaa agttgctgtt
     6181 aatccaatag caaatgtttg ccctgtcaaa ggaaccaaac caaaaggaat ggtcatctga
     6241 gaaaggacag aaataatcgc ggcaaattcc gcagcaagta tcaattcttt caatgttcgg
     6301 ttcataacgc cctcttttcg ttaacttaat atttttattt ggttaacgaa attgtaaaac
     6361 aaagtgatta ctttgtaaat agaaaatata aaaaaagacc agctatccaa tagatagcgg
     6421 tctttttcaa gaaagctttt gaaattataa gctttggttg tagtattcaa cgacaagagc
     6481 ttcgtcgatt tctggatata gttcgtcacg ttctggtaaa cgagtcaatg aaccttccaa
     6541 tttttcagcg tcaaagctta cgaatgctgg gcgtccaaca gttgcttcta cagcttcttt
     6601 tactgttacg atgttttgtg atttttcacg aactgagatc acttgaccca cttctacgtg
     6661 gtatgaaggg atatcaacgc gtttgccatc aactaaaatg tgaccatggt taactaattg
     6721 acgtgcttga cgacgagtcg ttgcaagtcc taaacggtaa acaacattgt ctaaacgttg
     6781 ttctagtaag atcatgaagt taacaccatg tttaccttct ttgattttgc tagcttttac
     6841 gaacaagtta cggaattgac gttcgttcat tccgtacatg tgacgaagtt tttgtttttc
     6901 agttaattgc atgccgtatt ctgattgttt gccacggcta ttaggtccat gttgacctgg
     6961 tgcgtaaggg cgacgtgcta attcttttcc tgtgcctgac aatgagatgc ctaagcgacg
     7021 agaaattttc catgatggtc ctgtataacg agacattaaa atttcctcca atgaatataa
     7081 gtttttggag taaaataatc cgttgaaaaa ttcataatca tatagtttgt tcttcaatct
     7141 tcacctttgc agccgcggtt acacaatcga acccgagacg gggcaacaaa ctagggatga
     7201 gttattattt ttctgctgca ttattttaca caaattacag tatatgatag atcatccacg
     7261 aatgtcaaga taattagtac ataaaaacgc tttacaaacc taggctgtct ttataaaatg
     7321 agagggtatg tgcaaatgga aaaaagcgaa ggaagtttaa ggagaaaatc aatgaatccg
     7381 gtatcaccat tatttgagaa aatcgatgct tcaattgaaa agaaggcgaa tctttttgaa
     7441 aacagctttt cacgttacgc tgttcgagcg gttctcgcct gtttgttttt gactttagga
     7501 acggctgtgg catttgcgat cgcgatgaag ggggaagata tcgcgcatgg tctaggaaag
     7561 attttatacg catttatgtt cagctggggt ctggtcatga ttctatacat gaacgccgaa
     7621 ttaggaacat cgaatatgct ttatatgacc gtgggtgttt ttcggcagag acttgcttta
     7681 agtaaggcag ccaagattct atttgcctgt atttttttca atatgattgg cggtatatta
     7741 tgtggatttc taatttctat gactacgcca tttcaagatt taacgttgga caactttatg
     7801 ttagaatcaa tagcagtaaa actagcaaaa ccttcagcaa cgattttggt ggaagggatg
     7861 tttgcgaata tcgttgtcaa taccgctgta ctgatcagca tgcggatgaa agaggatgtc
     7921 ggaaaagtga tcacagtcgt attcatcatt ttcatttttg cttttttagg atatgaacac
     7981 gtgatagcga attttcctgc ctttacgctt acttactttg cttctcacgg acagatggat
     8041 ggaatgacag tcagcaatgt gttacataat ttgttttttg ctttggcagg aaattatatt
     8101 ggtggcggtt tagtaatggg actgggatat gcttggctga atcagtcaaa atcatcctat
     8161 gtggactaaa aagtcgttca ttaaagggga agtgccatgg aagttttagt ttttccaaaa
     8221 aatgaggaaa aagcgttaca aatggaaaag tacatgaaaa atcttttttc ctttgctgga
     8281 gtacctaagc cggaacgcgc tcttttacaa caaccgttac tggatgagag caaaaattta
     8341 tctatttctg aagttttagc ttttgttcat tattattatg aacaaatcga aagagagtat
     8401 cagtatgtag cgatcgattt agtccagaaa aacatcaaac ggcttacatt tgaagactta
     8461 gtcgtattgt tgccactagt tcagaaaaaa gaatggtggg acagcatcga ctcttggaga
     8521 aaagtataca gcacatggtg taaagcctac ccagagcagc gtgaagaagt ctttcaattg
     8581 tttgaaaaaa aggaagattt ttggctacgt cgaatagcaa tcacgttgca attaggttat
     8641 aaacagcaaa cagacacagg actattgatc cgagcaatag acgaagatcg tcaaacaaag
     8701 gaattcttta tccaaaaagc aattggttgg gcattacgcg attatagtaa gaccgatgcc
     8761 gattgggtaa aaagacagct gacaacagat ttgagtaagt tagctgttcg agaggcaagt
     8821 aagtatttat aagaaagcga gacgacaaga gatgagacgc aaattatttg cttttgatat
     8881 tgatggaacg ttgttagatt caaacaaaca agctttagat agcacaagag aagcattgga
     8941 aaaattacgc aaagccggtc atctggtcac gattgctaca gggcggagcc gatttcatgc
     9001 gcaagagatc attcgcgatc ttgattttac gaactacatt ttatgtaatg gagcggccgg
     9061 ttttttagac catgaacaag tatataagaa tttactagat cgcgaccagt tggatgcgtt
     9121 cgttcaagaa gcgcatcatg agcagatcga tacagctttt gtcagcttag acaatatcaa
     9181 gcgttcttct tccaatgatg taacggtgat ggaagaagcg atgcattctt tcggtgctgt
     9241 cttgcctgaa ttagatcagt tttttgcaga ggaacaagaa atataccaag cgttagcatt
     9301 tttcgatcaa acatatgatg ggaagttctc ttcatatgat aaaattcgat ttgtccgctg
     9361 gcatgagaac agtgtagatg tcgtacctaa aaatggttct aaagcagcga caattctgca
     9421 cttagcagaa caagtaggca tccctcatga agacatcatc agctttggcg atggacaaaa
     9481 cgaccgtgaa atgttgcgca tgtcaggaat tgggatagct atggggaatg ctgtgccaga
     9541 agtacaagca gaagctaaga tggtcactga tacaaacgat caggatggaa tttggaaggc
     9601 attgaaagag ttaagcgtga tttaaaagag gttgtgaaaa agctgttctg catcaagtaa
     9661 taagcccagc caaacaaaaa tagctcctcc tatttttcgt ttttctgggc ttattaccgc
     9721 agatgcaagc tttcgaacac cgtttaagga agaggtcgtg acagaagtgg tcagtttcaa
     9781 gaaataagaa gggatttacg aaaattgctt ctcaaatttt tgtaaaatta cggcttattt
     9841 ctgaagaagt agatgaaaca acgtttattc gggaaatggg actgtgacaa gatgtttgtc
     9901 atagtcccat ttttttattt tatttttcaa aactaagaaa taccaggaaa gagttccttt
     9961 tgtttgacct tttctttctt attgaaaaca actataatat agagtgatgt taaaagagaa
    10021 gaggaattta gtgtgcgggt attgtttatt ggtgatgtag taggttcaat gggacgagag
    10081 atgattactg aatatcttcc tagattgaag aagaagtacc gtccgcaagt aacgattgta
    10141 aatggtgaga atgccgcttc tggacgtgga atcacagaaa aaatctataa aaaatttttg
    10201 caagacggcg tagatgtcgt gacgatgggg aatcatacgt gggacaaccg cggaatcttt
    10261 gagtttgtaa atgaagctaa aaagatggtt cgtccggcaa attttccgga agggacgcct
    10321 ggacaaggga tggtctttgt caaagtgaac caagtcgaac tggcagtgat caacatgcag
    10381 gctcgttctt ttatggtgga cttggatgat ccttttcgta aaatgaatga gctggtagaa
    10441 gaagccagaa aacgtacgcc gatcattttt gtagattttc atggagaaac aacaagtgaa
    10501 aaacaagcaa tgggctggtt tttagatggg aaagtttcag cagtggtcgg tacacataca
    10561 cacgttcaga caaatgatgc gcgaattttg ccaagaggaa cagcgtatct gacagacgtt
    10621 gggatgacag gtccctatga tggtattttg ggtatgcgca gagaacctgt aatcgaaaag
    10681 tttctgactg cattaccaaa acgttttgaa gttgtggaac aaggccgatc gattttaagc
    10741 ggctgtatct tggaattgga tgatacgaca ggtcatgcaa aagaaatcca gctgattcag
    10801 atcaacgatg atcgaccgtt catggagtag aaagagaggc agttttttgc agcaggagcc
    10861 ggaaattcaa aaagaagtaa ggaaactgac aaaactttta agagagaatg aaacgatcat
    10921 tcgctacaaa gaacttgaag aaaagatcca gcaaaaccag tatttagctg agttgagaga
    10981 aaaaatcaaa caagcgcaaa aagatgctgt tcattttgcc cactatgaca aaccagcagc
    11041 agaaaaagaa gcaatcaaac aagcggatca attcatgcaa gaatttgatc agcatccgct
    11101 tgttgtagct tatagaaaac agctgttgga agcagatgat ctgcttcatc atttaacaac
    11161 tatgatacaa gaagaaatca atggacaaat agaggaggaa aaacatgcct caaaaaacta
    11221 aaaatactcc tatgatggaa caatatctaa gcatcaaggc ccaataccaa gatgcttttt
    11281 tgttctatcg tttaggagac ttttatgaac tattttacga agatgcgatc aaagcgtcac
    11341 agcttttgga attaacgttg acgagcagaa atcgaaatgc agaagaacct attcctatgt
    11401 gcggtgtacc tcaccatgca gcacaaggat atatcgatgc cttgattgaa aaaggctata
    11461 aagtagcgat ttgcgagcag gtagaagatc caaagacgac taaagggatg gtcaagcgcg
    11521 aagtgatcca gctagtcact cctggtacag tcatggacag caaaggattg tcggcaaaag
    11581 acaacaattt tttaacagct gtagttagtc aaggaaatga atttggcttt gcttatgccg
    11641 atttaagtac gggagaattg aagacggctc ggttgcatga tgaagaagct gttttaaatg
    11701 aagcctctgc attgcagaca aaagaactcg tattaggcag tgagatcact gatacccttc
    11761 gtgaacagct aagcgggcgt ttagggctag tcttttctca acaaaatgag atggaagaaa
    11821 acgcggaatt tagctttttg acaagcgaac tagtcgatcc gctggaaaaa gaagcaaccg
    11881 gcaaactatt gacttattta tcggtgacac aaaagcggag tttagctcat atccaaaaag
    11941 cagtagaata ccaaccagat cattttttga aaatggatta ttattcaaaa ttcaacctag
    12001 aattaagcca atctattcgg actgggaaaa agcacggcac tcttctatgg ttgttagatg
    12061 aaacaaaaac agcaatgggt ggccgtttac taaaacaatg gctagaccgt ccgcttatcc
    12121 aggcaaaaca aattaaagca agacaagaaa tggtcgcttc tttgctagac agctattttg
    12181 aacgtatcga tttgcagtca gcattaacga aagtctatga tctggaacgc ctagcaggtc
    12241 gagtagcttt cggtaatgtc aatgggcgag acttgatcca gctgaaaact tctttagaac
    12301 aagtgccaat gatcagaggg ttgattgaag gaatcgatca aggtcaatgg caaagtctgc
    12361 tttcagaaat gcagccgatg gaccatctcg tccaattgat cgaccaagct atccaagatg
    12421 atccgccgtt acaaataacg gaaggaaaca tcatcaaaga tggattcaat gagcagctcg
    12481 atatgtaccg ttctgctatg agaaacggaa agaaatggtt ggcagaactt gaagcaaaag
    12541 agcgtcaaga aacaggaatc aagaacttaa aaatcggatt taaccgcgtt ttcggttatt
    12601 atatagaaat tacaaaagca aatcttggaa atgcagaact ggagaagtat gaacgaaaac
    12661 aaactttagc aaatgcagag cgtttcatca caccagaact aaaagaattg gagacacaaa
    12721 tcctcgaagc agaagaaaaa tctgttgatt tagaatatca gttgttttta gctgtgagag
    12781 aagaagtcaa aaaggctatc cagccgctac aagtacttgc aaaagcaatc agtgcagtag
    12841 atgtgctaca aagttttgca acgatcagcg aacgctatca gtatgttcgg ccagaacttg
    12901 tcagtgacaa gcatcagctt ctgatcaaag acggacgaca tcctgtagta gaaaaagtat
    12961 taggacatca ggaatatatc cctaacagcg tagaaatggc agaagacgaa atgatcttgc
    13021 tgattacagg accgaatatg tctggtaaaa gtacgtatat gcgacagttg gcattaactg
    13081 ttctgatggc gcaaatgggc tgtttcgttc cggcaaaaca agcagtttta cctatttttg
    13141 atcggatttt tacccgaatt ggtgcaagtg acgacttaat tgctggacaa agtactttta
    13201 tggtagagat gatggaagcc aatcaagccc tgcgttatgc tacgccaaac agtttgattt
    13261 tgtttgacga actagggcga ggaacagcaa cctatgacgg aatggcgttg gcccaagcaa
    13321 tcatcgaata tatccatcgt catgtacaag caaaaacact cttttctact cattatcatg
    13381 aactgacggt acttgagaaa gaacttccgc agcttaaaaa tgtccatgtt ggagccgttg
    13441 aaaaagacgg agaagttgtc ttcttgcata aaatgatgga tggacctgcg gataaaagct
    13501 acggcataca tgtggcaaag atcgcaggat tgccttccaa tctactagaa cgagcagcag
    13561 atatcctgca tacgctagaa aatggcgata acggacacca tactgttcca gctgaagtag
    13621 aagagaaaac taaaacagcc aaacaggagc aaataaaacc acctgcagaa aaagtaaatc
    13681 aagaccatat acaagaccgt gtaaaagaag aaaaccaaca gctttcttta ttcagtgaat
    13741 tatccgaaaa tgaaacagaa gtcattgaat cactgaagca aataaattta ctagaaatga
    13801 cgccaatgga tgcactaaac acattatatg aattacaaaa acaactgtag gaagaaggcg
    13861 gatatcgatg gccaaaatcc aagaattatc tgaacgttta gctaatcaga tcgctgcggg
    13921 agaagtagtg gagcgaccag cttccgttgt gaaagaatta gtggaaaatg caattgacgc
    13981 cggcagtact cagattgata tcttagttga agaagcggga ctgcggacga tccaagtgat
    14041 tgataacgga gaaggcattt tggcagacga cgtagagaat gccttcaagc ggcatgcgac
    14101 aagtaagatc cataatcgcg acgatctttt tcgcatacga acgctgggct ttcgagggga
    14161 agctttgcca agtattgcct ctgtttctga aatgactctg gaaacggcga atcaggaaga
    14221 aaaacaaggc acctatctgt cgctgaaagg cggagaagtt attgagcatc gaccagcacc
    14281 actgcgtcaa ggaacgaaga ttaccgtcag caatctgttt ttcaatacgc cagcccgctt
    14341 gaaatacgtg aaaacactgc acacagaatt agcgaacatc ggggacatcg tcaatcgact
    14401 ggcattgagt catccatcga ttgcttttcg tttagtacat gatggaaaca aaatgctggc
    14461 aactgctgga aatggcgatc tgaaacaaac aattgcggga atctacggat tatctaccgc
    14521 aaaaaaaatg ctgaaaatcg aaggaaaaga tctagatttt gagttatttg gctatgtttc
    14581 attgcctgag gtgactcgtg ccagtaggaa ttacttatcg acgatcatca atggacgttt
    14641 tatcaagaac ttttccttga ataaagcaat cgttgcaggt tatgggtcaa aattaatggt
    14701 cggtcgtttc cctattgctg tattggaaat caaaatggac ccgcttttag tagatgtaaa
    14761 tgttcatccg acgaagcagg aagtccggct gtcgaaggaa aaagaactaa cagagctaat
    14821 tagtaacgcc attcaaaaag cattgtctca agaaaatctg attccaagtg cagcggataa
    14881 tctacggttt aagaaaaaag tacctgatca gcctaaaaca gaacaaatcg aaatcgattt
    14941 gtcctacgct tttgaagaag aaaaacctaa aaagccaagt agtttgaatt ttgatcgaca
    15001 gacaggtacc tttttcgtag aagaactaaa gaacacattt gttgacagaa ttgttgataa
    15061 gtctgtggaa aatgttgaaa actattctgg tttttctgaa gaaaacacca cttatccaga
    15121 aaaaacagcg aaaacggtgg ataagtttgg tgaaaatgtt gataactttg tagaaaaaac
    15181 agtggaaaaa tctgaaaaga aagaatttcc cattgtggat aacatggaga aaacaaatga
    15241 agaacaagca gataaatccg tagaagagga tgaaaagatt tacgaggaag aattgacact
    15301 ccatcctgaa tttgatttca ctcaaggaaa cgacaaaaca ttagaacaag ccatcaagaa
    15361 attagaaacg gaaaaaccag tacaacgttt tcctcagttg gaatattttg gacagatgca
    15421 cggaacgtat ctttttgccc aaagtagcga tgggttgtac atcattgatc agcatgctgc
    15481 ccaagagcgc attaagtatg aatatttccg ggaaaaaatt ggggaagtat ctgatgatct
    15541 gcaagaattg cttgttccat ttgtgttaga ctatccaaac agtgatgctt tgaaattaaa
    15601 agagcaaaaa cacttgctag aagatgcagg gatttattta gaagaatttg gtcaaaacag
    15661 ctttattgta cgggcccatc ctacttggta tcccaatgga gaagaagaat cgattattcg
    15721 ggagatgatc gatatgctgc tgacaactgg aagtgtgagt gtaaaaaaat tccgtgaagc
    15781 aacagcaatc atgatgagtt gcaaacgatc gattaaagcc aaccattatt tgaatgaagc
    15841 acaagcacgt gtgctgctga aggatctggc acgatgcgaa aatcctttca attgtcccca
    15901 tggccgtcca gtattgattc actttaccaa ttcggatatg gaaaggatgt tcaaacgaat
    15961 ccaagacccg cattaagtca aagagaagag ggaaaacatg aagattgtat tagcatccca
    16021 atcaccaaga agaaaagagt tattggctca tatcgtttca gaattcgaga ttgaacctgc
    16081 tgatatcgat gaaacgccat ttccagacga acagcccgtc gattatgttc gtagaatggc
    16141 tgaagaaaaa gcacgaactg tctgggaaca agatgaaaaa gaagaccatt tagtgattgc
    16201 cagtgacacg actgttgttc tcaatcaaga gatcatgggt aaaccagaag atctggctga
    16261 ggctgaattc atgctgaaaa aactaagcgg ggaaacacat actgtatata cagctgttgt
    16321 tttaaaaaca aaggaacgag aagaacggat actagcagaa gcacatgtca ctttttatcc
    16381 tttgacagac gaagagatca aacgctactt ggagacgggg gattatgcgg ataaggcagg
    16441 ggcatacggc atccaaaatg ctgcgagtgt attcgtcaaa gaaatttctg gagattatta
    16501 cagtatcgta ggatttccga ttggtgctgt caatcaggca ctgaaaacat tcatttaaac
    16561 aaaaaagcgg actatctgat tttcgattga aaatccatga tagcccgttt tttttattga
    16621 aaagattact tatctactct gactaagatt ttacttcagc tttaccgact gcttcgcccg
    16681 ggcgaacaag tcctgattgg tcaagagaaa gtcctgcaac tttttcatta ttggtcaaag
    16741 caacaataat gtcagttttc ttgccagctt gttctatttc tggcaaatcc atttcagcaa
    16801 tcagggtctc tggtgtgaca aggtatcctt ctttcacgaa tacattgaaa ggaacaccct
    16861 ttagttcaac agtatctaat cccatgtgaa caagtacttc cagcccctca ttagaaagaa
    16921 taccaatggc atgttttgtt tcaaagacac tcgtcacttt accgtttact ggtgcataga
    16981 ctttgccgtt tgacggttcg acagcataac cgtcacccat cattttttgt gagaaaactg
    17041 ggtcatttac ttcagttatt tccttgatgg tccctgcagc gactgcgaat aatgtttctt
    17101 ttgttgcaac tgccgtacca gttgctgaaa caggttcgaa agactgtggc gttgctgttg
    17161 cgccatttgc tgtttgaagt tgtacatcag cagcattttc aggaacagca ggatcaatct
    17221 tattcaaaat tccctgacgt ctaaagatga tcgtcaagcc aaatggaatg atgacagcaa
    17281 tgatcattgc gatgatgaaa ggtacccatg tttctgcttg gatagctagt attcctggca
    17341 aaccgcctac tccgatcgcg ttagctcgaa cacccatcaa gttagcaaac atgccagcta
    17401 atccagagcc gaccattgca gcgacgaaag gatagacgta tttcaaattg attccgaaca
    17461 tagcaggttc agttacgcct aagtaacaag aaatcattgc tggaatcgag atttgttctt
    17521 cttttttatt cccacgatgt aagaagatga tggctaagac tgcagagcct tgggcgatat
    17581 ttgataaagc aatcatcggc cataaattcg ttgatccgaa atctgcaatc agctgcatat
    17641 cgatggcatt ggtcatatgg tggagaccag taatcactaa aggagcatac aggaatccga
    17701 atacggcact aaacaaccag ctgatagaag acgtcaatcc agtatttacg atatttgaga
    17761 tccagcttcc gactgtccag ccgataggac ctaaaataac gtgtgcagct aaaacagttg
    17821 gtaacaatga aaacaatgga acaaaaatca tcgagatcga ctgagggata tatttgcgga
    17881 agaagatttc tagatacgct aacataaacc ctgccagcat ggctggaata acttgcgctt
    17941 gataaccaat catctggact tgagcaaaac caaaatccca aaatggaata tctgctgcgg
    18001 ctgtggaagc tacactataa gcatttaata attgcggaga aactaacgta attcctaaaa
    18061 cgattcctaa tatttgtgta gtacccatct tttttgcaat actccaagtg atacctactg
    18121 gaagaaaatg gaaaattgct tcaccgggta accacaaaaa ggcattgaca ccattccaaa
    18181 acttcgagtg ttcaacgatt gttccaccaa gactttcaaa ctggatacct tcaagtacat
    18241 ttctgaatcc aaggatcaat ccaccgacaa tgattgcagg aatcagtggt gtaaagattt
    18301 ctgctaaaac ggcaatagca cgttgaacgg gatgaaggtt ttgttttgca gctgcttttc
    18361 cttgttcttt ggaaacccct tcaactccag atactgcaac gaagtcgtta taaaaagtag
    18421 aaacatcgtt tcctatgatg acttggaact gtcctgcatt cgtgaacatc ccttttacgc
    18481 taggtatatc ttcgatcgct ttttcgtccg cttttcctgg atcattcagg acaaaacgca
    18541 tacgagtcgc acaatgacta actgcagcaa tattttcttt tccgccgata tcatgtaaca
    18601 gcttctcggc atctgcttga tattttgcca tatcaataaa cccctttctc ttaacttgtc
    18661 tatgcaagtt gtttcttcat ttactatact ttttttcgga gagaattgca agcgttttat
    18721 taaaaagtac gagagaaaat gatatcgttt taaaaagctt aaaataagct tttcttaaaa
    18781 ataggaacat tgaaatacaa aaagagctgt agtatagtga agaaatgatg gaagaacgag
    18841 tgagggaaaa aacatgaata agttcaatga aattttttta gatttggaac agaaaatttt
    18901 agcgaaagaa tatcctccgc attcgctttt acccagtgag aaccaattga tcaaaattta
    18961 tggtgtttca cgagaaacaa ttagaaaagc gctgaatctt ttgactacgg aaggttatat
    19021 tcaaaaaaaa caaggaaaag gttcgatcgt actggatcgg aatcgcttcg actttcctat
    19081 ttctggactg actagctata aagagctaca ggagacccaa cgtattccaa gtgaaacgat
    19141 catccatacg ttagaagaaa cagaagtgac aaaagcattg aacgagatca ctggctggga
    19201 gatcggtgcg cctgtttggc atttgatacg cgaaagaaaa atcaatggcg aagtagttat
    19261 attagacacc gattatctat taaaggaaat cgttcctatt ttaactccag cacaagcaca
    19321 aggatcgatc tatgaatatt ttgaaaatga gctttctttg acgattgctt acgcgcaaaa
    19381 ggagatcaca gtagaagaag taacggaaat catgaaaaca gcgatggatc ttcacgatga
    19441 cacttatgca gtagtagtca gaagcctcgt tcatctggaa gatacccgct gtttcgagta
    19501 ttctgagtcg gttcaccgat tagataaatt ccgtttcgtt gagtttgccc gacgccgaaa
    19561 agtgtaaata gttcaaaaga aagcaaattg ttggcatctg tccactttgg cgctatgata
    19621 ggatcacaaa gggggcattt ttaatggata aaccaataag accagaaaaa gaagaactga
    19681 aagaaaagtt atcacccatg gcttatgcag tcacacaaga aaatgcaaca gaacgaccat
    19741 ttagcgggaa atatgatgat ttttacgaaa aggggatcta tgtagatatc gtcagcggtg
    19801 aaccgttatt cagctctgca gaaaaatatg atgcaggttg tggctggcca tcattcagca
    19861 aaccaataac gaaaagacaa gtgcgcgaaa aagccgattt ttctcatggc atgcatcgaa
    19921 tagaagttcg aagcaaagaa gcagattctc atctcggaca tgtgtttacc gatggaccag
    19981 tagatcaagg tggtctacgt tactgcatca attctgcctc actgaaattc attccatatg
    20041 aaaagatgga tgaattaggt tatggggaat tcaaatcact tgtagaataa tggaaataca
    20101 caaagagcgg tacaatacgg ggatttactc gatcgtccgc tcttttttta ttcaagcgat
    20161 tgctatttga aagaaacgct ccctagactc cttttttcac aaggtgaaat gtgctacaat
    20221 aaagggaacg tatgtgtgca aaagaaagag gactagaata tgtatgaata tctgacaggt
    20281 gtggttacct ttatcaaccc ctattacata gtagtagaaa ccaatggtat cggctaccag
    20341 atcgcactag gaaatcctta ccgctacagt agcaaactaa atcaaaaaat aaaaatttat
    20401 gtccatcagg taatacgtga agatgcgcat cttctgtatg gatttgattc gctagaagaa
    20461 aagcaactgt ttttgcgatt agtaagtgtt tcaggaatcg gtccgaaaag tgcccttgca
    20521 atcatggcaa gcgaagacca ctccggtttg attcaagcag tagaatccag tgatgtcact
    20581 tatttgacga aatttccagg agtagggaaa aagacagcac aacaaatgat cttggatcta
    20641 aaaggaaaat tcggtgagct gagtatcgat acacctttta gtctatttga tgaagcaaac
    20701 acaaaagacg ctacagctct atctgaagca atggaagctc tctcggctct tggttacagt
    20761 gatcgagaaa tcaaacgtgt agaaaaacaa ttaaaagaag tagataatca gacaacggat
    20821 gagtatctac gccaagcact caagctaatg atgaaaaaat aaggaggaga ccaaatgaca
    20881 gatgaatact tgttatcacc agaatctggc gaaaatgaac tgagtttgga aaaatctctt
    20941 cgaccacagc tgctttctca atatatcgga cagagaaaag tcaaacaaga acttcagatt
    21001 tacatcgaag ctgccagaaa tcgggaagaa cctttagatc atgttctgtt gtacgggcct
    21061 cctggattag gaaaaacgac gatggccatg gtcattgcta atgagatgac cgtaaatatt
    21121 cgtacgacga gtggccctgc tatcgaacgt ccgggtgact tagtagcaat cttgaatgaa
    21181 ctggaagcag gggatgtcct gtttatcgat gagatccatc gattacctag agtggtagaa
    21241 gagatgcttt attcagctat ggaagatttc tatgtagata tcatggtagg acaagggcca
    21301 accgcacatc cggttcattt ccctcttcct ccctttactt tgattggcgc gacgacacgg
    21361 gcaggtatgc tttctgcacc tttacgagat cgatttggca tcatttctca tatggaatat
    21421 tatgacgaac aggatctgca ggagatcgtt ttacgttctt cggatatttt tcaaacagag
    21481 atcattgaag aaggggcatt ggaaattgct cgccgatcac gaggaacgcc tagaatcgct
    21541 aatcgcttgc tcaaacgggt tcgtgatttt gcgcaagtcc aaggagacgg gaaaatcgat
    21601 cgtcctatag cggatcaggc acttactttg ctacaggtcg atcaggctgg attggattat
    21661 gttgaccaga aattgttgcg aacaatgatc gagttatatg gcggcggacc agtagggtta
    21721 agtacgcttt cagtaaacat aggagaagag cgtgagacgg tagaagatat gtatgaaccg
    21781 tatctgatcc aaaaaggatt tttaaagcgt acacctagag ggcgaattgc tactgcttat
    21841 gcctatgaac attttggtta cgactatcat atatgatttt tgcttttaga ttggaggaaa
    21901 atgaatgagt gatacaacac gtacgaaaca attgatcaaa aacgtattga ttgatttgtg
    21961 ccaaacgcaa tcttttcgaa aaatcagcgt ccaaaaaatc gcaaacgaag caaaaatcaa
    22021 tcgacaaaca ttttattatc attttacaga taaatacgat ttgcttcgtt gggtctattg
    22081 tgaggatgca ttgcattatt tagatccaca atgtctttca cttgataatt gggaagagca
    22141 agcattgaaa atgctgaaag caattgctga gaagaaagaa ttttatgcaa atactgtgct
    22201 ttctgaccca gaaattttac aaaaagagtt ttctcaactg atccaaaaat catttatcaa
    22261 gatttttgaa caaatggatg aagaaagaca actttctgca agagacaaac tattttatgc
    22321 tcgttttttt tcttacggtt gcagtggtgt attagtcaat tggatcacga atgaatatga
    22381 agaaacaccg atggaaatcg ctatgcagct tttccgttta gccaaggata cggaattata
    22441 ttcttatcgt ctttatgcaa aagaagagtt ggaagaacag taatagaaaa attttttgtt
    22501 ggaaaagcaa taatcgctaa aaggagatgg ggaaatgaca aaaattttat ttgtttgttt
    22561 gggaaatatt tgccgttcac cgatggcaga aggcttgctg agaaaacgaa tagcattaga
    22621 aggaagggaa gcagaatttt ttgtggattc tgctgctaca agcacgtatg aagttggaaa
    22681 gacaccgcac cctggaacga aaaaaatatt aaaccaagaa aaagtagata tgacgaatat
    22741 ggttgctcgg caaatcacac cccacgattt tgaaactttt gattggatca ttggcatgga
    22801 tcaagaaaat gtagaagaac tgaaacgaag agcaccacgc tcagcgcagg ggaaaatcca
    22861 tttgttttta agtagcattc ctggaaaaga aaaagaaaat gttcccgacc catactatac
    22921 caataacttt gatgagacat atcacttgat cacagaaggc ctgaatcatt ggtggaatat
    22981 ttggattgat gaaaataaaa taacaaacaa tttgtaaagt taacgctttc tttttaaggc
    23041 gatgttagag catttccttg tttttttgta aaatgttagg taaaataaaa ttaattaagt
    23101 aacactttct tagctaaagg aggagtgcat tcgatgaacg aagagacagt atcgccaatg
    23161 aagaagctta cgaagttagt tactcatact tcgtatcaac tttttgattc ttttgtaaat
    23221 gacactgaag aacatgctaa gaatgtacga ttgcaaggaa agtttattct tgagctgcaa
    23281 aaagctgcta ctgaacatag tctagttatc ttacaagtaa gagcaaatcg tttgagtagc
    23341 aagtatgaaa cgatctcagg ctgggtggcg acaaaaacgg tcgaaaaaga ccgagtgatg
    23401 atccgcctac aaaacgaaga gcagcagatc cggatggttc ctgtagaaca aattgaaaaa
    23461 ataacaatcc tttcaccagc aggggaacag gaacggttat caaaataatt tataccagat
    23521 agaaaagcac gtatgagctt gtaccatcaa tcattactaa tcaaaaataa ccgaatgctt
    23581 taagctgata tcagtaaaac ggaacgtttt aggatgagta tcatagcatg acagcattcg
    23641 gttgattagt tgaatcgatt ggatggtaca agtttttttg ataaaaaaag gtcctgctag
    23701 ccggggagct agcaggataa ggagttaaaa atgaaaaagt gttgttaggg ttgtttgttg
    23761 gtatgcttat ataatagtca ttagttgtga atattttgtg acgaaagttt tcgaaagttg
    23821 ttaagttt
//
LOCUS       DACGEU010000039        23772 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.039, whole genome shotgun sequence.
ACCESSION   DACGEU010000039 DACGEU010000000
VERSION     DACGEU010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23772)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23772)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23772
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.039"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(387..1853)
                     /locus_tag="IXR40_001468"
     CDS             complement(387..1853)
                     /locus_tag="IXR40_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAQ4361324.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
     gene            complement(2144..4228)
                     /gene="cadA"
                     /locus_tag="IXR40_001469"
     CDS             complement(2144..4228)
                     /gene="cadA"
                     /locus_tag="IXR40_001469"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HAQ4361325.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQETKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTTEGLMTVNPEDVQIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKKFMQYIASAEQFSTHPIAQSVLEGYAGPLLP
                     TTNIQEFAGEGILAEVDGKQVLAGNHKLMERFEISFPLSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKQAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQRNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLALGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKKEDE"
     gene            complement(4370..4549)
                     /locus_tag="IXR40_001470"
                     /pseudo
     CDS             complement(4370..4549)
                     /locus_tag="IXR40_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308695.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cyclase family protein"
     gene            complement(4753..5112)
                     /locus_tag="IXR40_001471"
     CDS             complement(4753..5112)
                     /locus_tag="IXR40_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HAQ4361326.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            complement(5142..5483)
                     /locus_tag="IXR40_001472"
     CDS             complement(5142..5483)
                     /locus_tag="IXR40_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361327.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERVDQRPSGKLIQHTLVTKENTEEIQKKFAEYLMLEAK
                     KRRIKSIFAQF"
     gene            complement(5480..6154)
                     /locus_tag="IXR40_001473"
     CDS             complement(5480..6154)
                     /locus_tag="IXR40_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HAQ4361328.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLISQYPTM
                     KFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTAEICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIAYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            complement(7330..8628)
                     /gene="asnS"
                     /locus_tag="IXR40_001474"
     CDS             complement(7330..8628)
                     /gene="asnS"
                     /locus_tag="IXR40_001474"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HAQ4361329.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVSEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            complement(8668..9858)
                     /locus_tag="IXR40_001475"
     CDS             complement(8668..9858)
                     /locus_tag="IXR40_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAQ4361330.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNPVIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYPLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            complement(9879..10406)
                     /locus_tag="IXR40_001476"
     CDS             complement(9879..10406)
                     /locus_tag="IXR40_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAQ4361331.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEETDHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            complement(10453..13242)
                     /locus_tag="IXR40_001477"
     CDS             complement(10453..13242)
                     /locus_tag="IXR40_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HAQ4361332.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDNFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGIGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLVQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            complement(13389..13589)
                     /locus_tag="IXR40_001478"
     CDS             complement(13389..13589)
                     /locus_tag="IXR40_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAQ4361333.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            complement(14042..14362)
                     /locus_tag="IXR40_001479"
     CDS             complement(14042..14362)
                     /locus_tag="IXR40_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361334.1"
                     /translation="MKKRLLWCLLSLSLSLTSQPVFAEETQRFPITGTRLYKNVYVQT
                     PDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
     gene            complement(14865..15983)
                     /locus_tag="IXR40_001480"
     CDS             complement(14865..15983)
                     /locus_tag="IXR40_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361335.1"
                     /translation="MAKKDKELLSQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            16454..17761
                     /locus_tag="IXR40_001481"
     CDS             16454..17761
                     /locus_tag="IXR40_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HAQ4361336.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWDDKVSISDYAENLSVT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETARLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAE
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFGNLF"
     gene            17882..19081
                     /locus_tag="IXR40_001482"
     CDS             17882..19081
                     /locus_tag="IXR40_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HAQ4361337.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYSSTWTFAVI
                     LTYFVVLEIFYSTFYFLIPLVFFSIFAFSYFSEKRRLLNGLLFNIFLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVFLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCIPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYWAQSRATLNPPILLMSGGQGADEKVPE
                     AMAMKQYAMEQGIPERDILVETNSTTTLENMRYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYARQAKLKANGIGAKTAFYYLPNAFLREYIAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(19108..20376)
                     /locus_tag="IXR40_001483"
     CDS             complement(19108..20376)
                     /locus_tag="IXR40_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HAQ4361338.1"
                     /translation="MEKQLPSPVRILMYMLKWLVVTAILGVFMGSLSAFFLNSLTFVT
                     DIRLAHPWLLYLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNIAHLFRLDKAEREILVISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVWRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHAYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAVLA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAAYFFMICLISFMCSGN
                     SGIYSAQQVAVKKGILFLPIVKRIKEKNKV"
     gene            complement(20546..21187)
                     /locus_tag="IXR40_001484"
     CDS             complement(20546..21187)
                     /locus_tag="IXR40_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G-binding protein"
                     /protein_id="HAQ4361339.1"
                     /translation="MEQTMKPYQYFFIKREVEQLLNAYSSVNDSKTVQTVQALAAEKI
                     RDVLGYEPSEIDTFLTTVLDVKLTKTQAERALEELKQIVQPFMQPSKPQIEKLFRKVK
                     KLKQPAWNEIDLQAHTYIGWNDPGTQKKFMVYYEDGKLKGISGTLSPTINKGICAICQ
                     KTSNVSLFLSTTKAGSDGTYTKKGNYICHDSDQCNQQLTKLAPFYEFAERVKK"
     gene            complement(21596..22099)
                     /locus_tag="IXR40_001485"
     CDS             complement(21596..22099)
                     /locus_tag="IXR40_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAQ4361340.1"
                     /translation="MTEKWREDEEYMSYVEDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TDLSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(22222..22986)
                     /locus_tag="IXR40_001486"
     CDS             complement(22222..22986)
                     /locus_tag="IXR40_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HAQ4361341.1"
                     /translation="MKEIQSAKNPRIKELKKLHKKKYREEKEEYLLEGFHLIEEAASS
                     DAEIKELFVTQRGMKEWGDWLAANKEISTFLVSDEVMDAVSDLPTPQGILAVMALTAE
                     GTPDFSGGWLLLDNVQDPGNVGTMIRTADAFDMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLTEVIPLMKDKGFTVYGTELNEEAHALDKVEKSDNFAIIMGNEGQGVSQ
                     EILSLTDQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            23094..23369
                     /locus_tag="IXR40_001487"
     CDS             23094..23369
                     /locus_tag="IXR40_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HAQ4361342.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
BASE COUNT         6878 a         5065 c         4149 g         7680 t
ORIGIN      
        1 aataaatggt gttcaatcag ctgaccttca gcattagctc aaaaagcggc aaaatatgag
       61 gagctatttt tccgtttgtt tctctaatac tcaggtcaaa tcgctgattt tacaacctct
      121 tccttaaacg gtgttccaaa gcttgcatct gcggtaataa gcccagccaa acgaaaaata
      181 tgaggggcta tttttgtttg gctgttctta ttacttgatg caggacagct ttttcacaac
      241 ctctgattca cggtgttcca gaagtagctt cttcgaaaaa caagccgaaa cttcacaaaa
      301 atttgagaag caattttcgt aaattccttc ttatttcttg aagctgacca cttctgtcac
      361 aacctcttgt aacaagtatt tctattttaa ggctgaacca ctgtttctgg ttcagtgatt
      421 tctttgtttt tgtctcgacg agcaattgct ggcaagatca tacctaataa gatcaagacg
      481 attggtgtga tgatattcgt aaataattgg aaccaccatg ctttaggatc agcagtataa
      541 tctacttttg gcaccattcc taggatacat gcaaacgcag tgaaggcaaa gcaccaagca
      601 ccaaagataa aaccgatttt tggattttta acaaatttat attcagaatt gaatttctta
      661 taagctttat tcaacatcat atatgccaag aacacccata ggtaacgcat tggcatgaca
      721 actgagttca agttcgtcaa ccattttact aattcattca tatctttgat accaaaaatc
      781 ggcaacaaaa taatgattcc tactagtata cctgtcagaa gataaccatt caccaatgta
      841 cctttacgat tacgtttacg tagccagttt ggtacaaatt ctggatccgc atctgctaac
      901 aagattttta gtggtgcatc aattgaaaag gctaatgcgg agatttgtcc aatcatgttt
      961 gtcaatgcgt aaatgatcat caatgagtta ccgataccat agtaattacc taaaatttga
     1021 aaagcactgt atgccccatt tgccatcaag tctttaggaa tattatcact agcaaacagc
     1081 atacccattg cgactgagcc taatacagca caaatcccta ccattgctgc taagaagatc
     1141 atccctttag gaaattcctt tgcaggattt cttgtagagt tgacataagg ggatattttt
     1201 tccgcccctc caactgcaaa tactagcatc gaaacggttg tgaaataact gaaatcaaat
     1261 gttggaatat atgttttcac ttgattcata tgtggtgtgg caaattccat cgttggattg
     1321 atgaacggtg ccgttacagc taaaagaata aataagatcg acatgacgaa catcgctgtt
     1381 ccggccagtc cgccaatcac tttcaaagta gaaagtcctt ttgttgataa atataaaaag
     1441 gcaagaaata taataagtga aataactgct accatttgta ctgacatcgt atttacgata
     1501 tttccatttc cttggactgc ccaaccacca gcaatcagaa ttgcttgagg cttttgtgcc
     1561 aaataaggaa tatggacgac ccagtaagtc caagcggcat agtatgccag tcgtttatta
     1621 gatgtcgtat tttcgaccca tgaactgacg cctcctttac tatccttgaa ggctgatcct
     1681 aattgtccaa cgatcaatgc gtatggaata aaataaatgg ccaaaatcaa tagccaagag
     1741 gtgacaactg atactccttg ctgagcatag ttattaacta cattccccat gccccaaacc
     1801 atgttaaatg caattaacgc aacagtaaac cagcgtaatt gtttgttgtt cattcgttct
     1861 ctcctttatg ataaaaattt gttatccaga tgtaatcata ttcaattttt aacaaactta
     1921 caagacagtg ttattttatg tgtgtattct tttatttaat acacatcgtt ttttcatatt
     1981 ttttccatca aaaaaataag ttattttctt ttatttcatt gaccttattg aatttcaagc
     2041 tattttgaat tttctgcaaa attaaaaaca ttagttattt tataatccta tctattttct
     2101 ttacattttt cattaagaaa aggatataaa aaaaagagga cgttcattcg tcctcttttt
     2161 ttacatgcaa gcttcgcatg gcattcaaaa cagctaatac tgtcacccca acatctgcaa
     2221 atactgcatc tcccattgat gcaaaaccaa aagcacctaa ggcaagtacc aaaattttta
     2281 tcccaatagc aaagacaatg ttttgtttga cgattttcaa tgttttcttt gctaaatgga
     2341 ttgcttctgc aatcttcgat ggttgatcat tcatgatgac tacatctgct gcttcaattg
     2401 cagcatcgct tcccaatcca cccattgcga ttcctacatc tgctcttgct agcaccggtg
     2461 catcgttgat tccatctccg acaaatgcgg tctttttatt gtttctttgt aagatttcct
     2521 ctaaccgctg cactttatct tcaggaagca attcgctata tatcttgtcc acgcctactt
     2581 gcttcccgat atgatcagca atttttttcg agtcgcccgt caacatgact gtgttcttca
     2641 caccagcctg ttttaattga accaatgcgt ctacggcatc ttctttcaag gtatctgcaa
     2701 taacaagata accactgtaa ctttgatcga tcgctagata aagcaatgta ccgatttctt
     2761 gacttaaagg aaaagagatt tcaaatcttt ccatcaattt gtgattacct gctaatactt
     2821 gtttgccatc aacttcagct aagatccctt cacctgcaaa ttcctggata ttagttgttg
     2881 gtaaaagcgg acctgcgtag ccttctaaaa cagattgagc aatcggatgt gtagaaaact
     2941 gttctgcact cgcaatatat tgcatgaatt tctttggatc gatttttgta tcgatcgtct
     3001 ggatcgaaaa gtcacctttc gttaatgtgc cggttttatc gaataccact gtctcggttt
     3061 gcgcaagcaa ctccaagtaa tttgaacctt ttactaatac accgatttta cttgcgcctc
     3121 cgataccgcc aaagaaacta agtggcacgg aaatcactaa tgcacatgga catgagatca
     3181 ctaaaaatgt caatgctcga tagatccatt cagaaaacgc cgctccagaa acaacaagtg
     3241 gaggtaaaac agctaataaa acggccaatc ctacaacgac tggtgtgtaa tagcgcgcga
     3301 atttagtaat gaaattttca gctggtgctt ttttactgct ggcattttct actaattcta
     3361 ataatttgct gatagtagaa ttttcataag atttttctac ttgaactaaa aatggtttat
     3421 ttttattgat aaatccgctt aatactgttt caccaacata tacagattta gggactgatt
     3481 ctcctgtaag tgctgacgta tcgactaatg attctccttc gatgatcgtt ccatctaacg
     3541 gtacacgttc accaggcttc acaagtacaa actgaccgat ctgcacgtct tcagggttca
     3601 cggtcatcaa tccttccgtc gtctgcacgt gagctgtttc tggacggatc gccatcaatt
     3661 cgcgaatcga ttttcttgaa tgactgactg ccaatccttg gaaatactcg ccgatttgat
     3721 aaaatagcat cactgctacg gcttctggat attcaccgat caacatagcg ccaatcgtag
     3781 caacagacat aagaaaattc tcatcaaaga tttttccttt gacgatattc atcactgcct
     3841 tcttcactac atcatatcct atcagcagat aaatcaataa ataccctatc aagcgaattg
     3901 gttcattaaa atcaaataat agcaataaag cgatacctgc aagggaaaat aaaatccgga
     3961 acagcgtatt tctctctttt tcatttccat gttcagatac tttttcctta tctatttctg
     4021 ttactttgac atctggttct aattccttca ctactttttt tgtttcttgt tcaatcgtag
     4081 ccaaatgatc ttcctctgcg tcaatcgtta gttttccaga agtgaagttt accgttgctt
     4141 ccttgactcc attgatcttc tgaactcctt tttcgatttt cattgcacag ttcgcacaat
     4201 ctaaaccttc taatctgtaa cttttcattt taatgacctc ctcgcctcaa catatgaaca
     4261 tctcttcata actaattata aatgaatggt tattcatatg tcaaggtatc cgaaagaaaa
     4321 aatgaaaaac atctgcatcg gaaaatttct tccatacaga tgttttggct tattctttct
     4381 ttttctcttc gatcattgcc cctgctctta tccaacccgc acttgccttc ttgatcttga
     4441 caggatagca actaagtttg aagcctgttg ctggcaattt gtctaaattc attaattttt
     4501 cgataggaca atatcttttt tcaatccctg caaaatgtcc ttcccagata ttcgaagctc
     4561 cactacgctt tcaaaaatat agaaagagtt ctttaatgaa aattatttca actttccata
     4621 aacagtaatc ccatataaat aaaagacgta aaagtcacat gggagaactt atacaggaaa
     4681 acacatagag tcaggtgaaa tacatgtatc ccacctgact ctatgcgttt tctaaccttt
     4741 attattctct ttttatacaa tttctgcacc gaatggcatc aacgccaatc gagcaagttt
     4801 gaaagattgc ttggcaaaag gtatccctat gatcgtgata catagaagga tgccgctgac
     4861 gacatgtgcg agagcaattg gtaggcctga aacgatcagc cagatgatat taacgatcaa
     4921 tgacatgcca gactggtgat aaattacttc tttgccaaaa ggcgcaaaag aaagggaggc
     4981 gatcttaaaa cattgcatac cgattgggat acctatgatc gtgatacacc aaagtatccc
     5041 cgctgctaac cagctaagac caccgattag tccgccgaat ataaaccaga tgacatttcc
     5101 taaacaactc attgtatttc tccttctatt actgtttttg attaaaactg ggcaaaaatt
     5161 gattttattc ttcttttttt agcttccagc atcaagtatt ctgcaaattt tttttggatt
     5221 tcttccgtat tttcttttgt tactaatgtg tgttggatta gttttcctga tggtcgctga
     5281 tccacccgtt cttctgactg ttgcacgtcc gcttgcgcaa atccgataat ccgtttttct
     5341 tttgttacag caacgagcaa tagtttattc ttatcattta ggtcagctgc cgtttttgct
     5401 tttacgaatg attctggatg atcagtaatc agctgattga tttgaggtaa atcttctttt
     5461 actgcccacc gtatttccat catttctcac ttttctttcg ctcattttta tctccactaa
     5521 aaaaatcgac tgcggcaatt gcatctatcc agctttgtgc aatgatctca tgtccgccaa
     5581 tcgttgggtg gaccccatct tctcttgtat atttcgaaaa accataagca atccctaaag
     5641 cattgaatat gccatctaaa ggaaccagca atgcgccata ttccttagca agtttacgaa
     5701 caatttggat tttagggtct aagtctttac gccagccatg acggtcgtcg gttataggaa
     5761 gtacaaacgg ctccatcaag atgatgttgc agatttccgc tgtttgaagt tcatttagta
     5821 attttcgata aacggattca aattgctgcg cagatttctc agttccgaat atagcctgat
     5881 cgctagtatt atgccaggta tcattgattc cgatcaaaat cgatacatag tcaggttgta
     5941 aagctaaaca atcttcttgc cagcgtactt gcagatctgc aattttgtct cctcctatcc
     6001 cacggttcat gcattcaaat ttcatcgttg gatattggga gattagtttt ccggcaatca
     6061 aaagtggata acctttacct agatcagttg cttctgctcg gtctcttcct gcgtctgtaa
     6121 tgctgtcacc gataaataat atacgttttt tcatttgtca aaaactcctt tttgaataaa
     6181 acgatgattt tcttccttat attatcccat aagccctatc aagacgaaag agaaaatata
     6241 tgtataaaaa atgacaccag cctagtccct tcaatcaatt gaatgaacgc tcatcaagtg
     6301 tctagttttt tatacttttt ttcttaacgt gccggattcc ccttgattcc ttcgttgttt
     6361 ggtccagaga aatcgatcac acctaagctt ccgtcaatca gaccactgat gacgccatca
     6421 gaacatatat ttataggctc atctaagact tccagtaaat gttcttttac taatatctct
     6481 tctagattgc ttgggataga ttggtcataa ctttatctgg tccgatgatt tcaaggatga
     6541 attaaactta catatggatc attgcatgct gaaaatacgg acctactcca tcttcgaatg
     6601 ttactattag tttgttttca ggtactagat gctgctttat ttcaacagca gaagcatcat
     6661 caaatcagat ttccatttga ataaccttct ttgtatatgt ttgattgatt gcgatttcgt
     6721 tatagaacct tgtgaatcaa atagcaattt cttttgcttt cttctcttgt ctgctggaaa
     6781 cttcctttat cccgtatttt aaaaaaagaa ctgcgagagt tcgcagttct tttttttaaa
     6841 taaacgttgc tctccggcca actcctcggt cacaagtcac aatagtcatc aaacatgaaa
     6901 aactgttttt tgaaattact ccttgtgact cggagctgaa cggcaggcgc acaacctctt
     6961 gatataaacg gtgttcaatc agctgaccct cgatattagc taaaaaaacg gtaaaatatg
     7021 agaagctatt tttccgtttt gtttctctaa tactcaggtc aaggcactga tttcacaacc
     7081 tcttccttaa acggtgttca aaagccagtt tctcggtatt aagccaaatt tatgcaaaaa
     7141 tgtggaaagc catttccaca aaatttttct taatactcga aactaaacag ctttttcaca
     7201 acctctccac taaacggtat tcaaaagctt acatctgcgg taataagtcc cgccaattca
     7261 aaaacatgaa cagctgtttt tgcttggctg ttctaattac ttgatgcaga acagcttttt
     7321 catcacctct tatggataaa ttcggttcaa caaacgtggg aatggaatag cttcacgtac
     7381 atggtcgata ccagcaatcc aagtgactgt tcgttcaagg cctagaccaa aaccagagtg
     7441 cggaacagaa ccgtatttac gtagatcaag ataccatgaa tattcttttt catccaaacc
     7501 gtgattacgg atttgttcta gcaagaaatc atagtctgtt gcccgttcgc ttccgccaat
     7561 aatttcaccg taaccttctg gtgcgatcat atctgcacaa attaccacgt cttctcttgt
     7621 tggatgtggt ttcatgtaga atggcttgat ggcttttgga tagtttagga taaagacagg
     7681 ctgttcgaat gaattcgcaa tgaacgtttc atgaggtgaa ccaaagtctt cgccccattc
     7741 gatgtcatca aatccatttt tcttcagtaa ttcgattgca tcatcgtaag taatacgagg
     7801 gaatggcaat tttgtataag tttttaagac ttctttgtct cgtcctagta catctaatgc
     7861 atattcgcaa tgatctaaaa cattttgtac taagaatgct acatattgtt cctgtacttc
     7921 taaactttct tcttgatgag tgaaagccat ttctggttcg atcatccaga attcgatcaa
     7981 atgacgtcgt gtttttgatt tttcagcacg gaaagtcgga ccgaatgaaa agacttttcc
     8041 gaaagccata gcagcagctt ccatgtataa ttggccactt tgagataaat aagctttttg
     8101 atcaaagtaa tttgtttcga atagatccgt agtgccttct ggtgcagaac cagtcaagat
     8161 cggcggatcg attttgacaa aatgatgttg attaaagaat tcatacgttg cacgaatgat
     8221 ttcatttctg atctgcataa tcgcatgttg tcttgaagaa cgcagccata aatgacgatg
     8281 atccatcaag aaatctgttc cgtgttcttt tggtgtgatc ggataatcgt ggctctcgct
     8341 taccacttcc acatttgtaa ttccgatttc ataaccaaat tttgaacgac tgtcttcacg
     8401 gatttctcca gttactaaca cggatgtttc ttggtgtaga tttttagctg tttggaaaac
     8461 ttcttccgac acttcgcttt ttacaactac accttggaaa aaggctgttc cgtctcttaa
     8521 ttgtaaaaat gcgatttttc cgcttgatcg cttatttgcg acccaagcgc cgattgttac
     8581 tgtttctccc acatggtttt tcgaatcgat gatttgaatt tgttccacgt atgactctcc
     8641 ttttatattc cttgaatttc ttcaggatta attttgactt ttactctcaa taaattgctt
     8701 gattctgcgt accgcttctt ctaacgtagc gcgatcagtg gcataactca tgcggacatt
     8761 ttctggtgcc ccaaagcctt cgccagtcac aagcgctacc cctgtttctt ctaaaagatc
     8821 ttctacccat tgtgtgacat tttcatactt acacatgcgt agcgtttctt ttacattagg
     8881 aaaaagatag aaagctcctt gcggcttttc aagagaaaca cccggcagtt ctgccacaag
     8941 cggatataac gtattcaggc gttcttcaaa ggcgttccgc atttcttcta ctgtatcttg
     9001 ctcacctttc aatgcttcaa cagctgcata ttgactgact gctgtcggat tgctagttga
     9061 ttgggaagca acagcgatca ttccattgat gatcacagga tttcccaccg cataaccaat
     9121 gcgccagcct gtcatcgcat atgttttaga cacgccgttg atgatgatgg tctgattttt
     9181 gattgcttct gaaatcgttg caattggagt aaactcattg ccattataaa ctaaacggcc
     9241 ataaatatca tcagcaacta tcaaaatatc attttttact gcccattcac cgattgcctg
     9301 cagttcattc ttgctataaa tcattccagt cggattcgat ggagaattga tgattacggc
     9361 ttttgttttt tctgaacgtg cttgttctag ctgttcaaca gtaactttcc agctattgga
     9421 ttcttcccct ttcacaaaga caggaagtcc ttctgccagt tttacttgct caccgtaact
     9481 gacccagtaa ggcacaggaa tgatgacttc atcttgcggg tcaaggatcg tttggaaaag
     9541 ggtatacaaa gcaaatttcg ctccgtctgt tacgactgtt tgtgaaggtt catagacaag
     9601 tccatagttt ttcttcagat aatcaacgat tgcctgtcga agctctggga ttcctgctgt
     9661 tggtgtataa tagctagctt tcccattgcg gattgcttcg attgctgctt cttggatgtt
     9721 ttctggtgtc gcaaaatccg gttctcccac agtcaaactc agcacatctc tgccttttgc
     9781 ttttaatgcc ttggcctttg ccgcagctgc caaagtgaca gacggttcta atcgttttgt
     9841 tctttttgat aactccatcc cattcattcc tttacctttt aaattccctt gattgtcttg
     9901 acttcatctc cagattcaaa gccaatcagg taataattca gtttcccatt tgtttctttt
     9961 cctactactt cccacacagg ctgatcatca tacatcccta aagcagcttt ttcgatttgg
    10021 atttcaggat gggccgcagc aattgtctgt tttgcttcgt tttcagtcag tccctttgtt
    10081 tgatccaata cttttacttt ttcaccagat ttaggaatga taacggcgat ttcttttcct
    10141 ttatcatttg tacctgtcag tgaaaagtat gtcttctttc gagtaaacca ataaaaatga
    10201 tcggtttcct caagatttgc atatttcttt gcgatttcta ctgcttcttt cttcgcctgc
    10261 accgccggac gactggaacg caagtaaaaa atcgagctga tcacgatgac cgctaataaa
    10321 aatacgatca agccaagtaa cacgcgatta atcgtttttt cctttgtctg ttttttcttc
    10381 aagggtcgtc gctcctttat cttcattcct tttcattata gcagatttta attatgaaaa
    10441 aagacagctc ctctaacttc cttcttcatt tttctttaag aattcatgga tatcctgata
    10501 gatttcctcc atagctagct ctttgatcgg tacttttttc ggtaatgcat ggatgatccg
    10561 tgcgccatat tttgcagtga ctagtcttcg atccaaaata agcaatacgc cacgatctgt
    10621 ctccgtcctt atcaagcgac ctaatgcttg gcgtaacttc aaagctgctt taggtacgga
    10681 ttcctggtaa aaaggattga tcccctctga ttctaaataa gcgttcctag ctttgaccat
    10741 cgggcgaagc ggattatcga agggtaaacg tgtgactaca acgatctgca aagcatctcc
    10801 aggcaaatct acaccttccc aaaagctgtc agcgccaaac aatacgcttt tttctgacaa
    10861 aatgaagcgt ttcaaaagct tctcccggct tccaccaaac ccttgagcta gtatttctcg
    10921 tcctttttct agcatagaca gatgcatttt ctgatagacc ttctgcaaaa catcatgaga
    10981 agtgaataac acaagtattg gccgatcttc ttgttcgatc agacctgtaa gtgctgtctc
    11041 taaataatcg atatatgctt gattgctgac ttgatggacg gcaggtgcct cttttggcac
    11101 atagatcctt gcctgtttct cataatcata aggagaggca atcactttaa gaggtgctgc
    11161 ttcaatgcca agcctcttag agagatagtg tcgattaggg ccgatcttca gcgttcctcc
    11221 aatataaaga atacgatcat atcgaggata ccaaacagtc gacggcaaca tagccgcttg
    11281 aaaatcatgg agatgaaaaa tcatctgctg cgctgtgttc ccaggaacga accaatggat
    11341 caaatgatct cgccagtctt ccagccattg atccatcagc aagtattgct tgtctaattg
    11401 atcaaatagg ctatataaac ttgctaaatc gatccgcatc tggtttgtcc agctttcttg
    11461 gataatctca aaagtcagac gcatttgtga ctgtagctgc tggatctcct gataaaaaag
    11521 ctgcaggtga tcaatggctg tcccagattc cagtggcagc tgatccaaca tctcttttgt
    11581 catcatgact tcttctggat actgtccgtt aggttgcttg ccgctcacta aactcattaa
    11641 tccttctgcc atacaaatct gtgcttcgca tagcgcagaa agttcttctc gataaatcga
    11701 taaccagcgt aaggcttcat gttctttcgg taaatagctt tgtattcggt caaacagctg
    11761 atttggttct tctaattgct ggatttgttt atggaaatag ttaatactta atcgtttgtc
    11821 atttactttt tcagcgattt ccggcaaatg atgtacttca tcgatcaaca aaaatggact
    11881 agctggaagc aatggttctt ttcgctgtgt ttcttgtact aaaaacgcat gattgacaat
    11941 caaaaaatta ctttgcctga ttttcttttg caagaaacga acaaagtctt gttcgtaaaa
    12001 tgactgattt cttgctaaaa atccaatacc tctgtgcgcg atatctgcaa agaatgaatg
    12061 gttcaaattt gttaaatgta attcatccaa atcaccagtc ttcgtttgcg tcagccaaac
    12121 taagaccgcc atttgataca aagcatattg tttttgttct ggcggttcca caagtgtgcc
    12181 tttaaaacgc tgcaaatcaa tatagtggcg atagcttttg ataattacag gttgtatggg
    12241 ctgatctagc aattgattca gcaatggaat gtctttttct atgatctgct gctgcaaaac
    12301 tagcgaaacg gtactgatga cagcgggttt ttcaggtgta gccaaataac tcaatggcag
    12361 cagataaccg attgttttac ccattcctgt agctgcttcg atcatcaaat cttttgattc
    12421 atcttttgtg aaattgtcgt agaccgcatt catcagtctg ttctgttctt ttcgatacat
    12481 cagtgtttta ccaaacattt tttcttttgc ttgttttttt cttggatatg tccgctcgcc
    12541 ataatggacg gatgtgaata gttccacttc ttttttctgc aaagctagcc catcgacgat
    12601 ttctaatgag ggatcaagtg gctctggttt ttctttcatt tcttcaatca catgataaat
    12661 gaaacgactc gtatccatac ctgtgtgtct acttaatcgc gcaatctgct ctaacgtgat
    12721 gattggcaat tttctcatcc gttcttcgat cagcaaaaga agttgacctg tcacttcggc
    12781 atcactatct gcctgatgag gattctcatg aataaatcca aggctttctg acaaatcagc
    12841 taagcgaaag cttggttccg tcggcaagaa aatttgtgca agttctactg tatcgatgcc
    12901 tggtatcttc aaactaggaa gtccgcatcg catgagttca tggttcaaaa aattataatc
    12961 aaaataaata ttatgcgcga caaatatggt gtctgccaaa agattgtaaa tcgtttgggc
    13021 gacatcttcg aaataaggcg ctttttggac gcgttgattc gtgatccctg ttaaatgctg
    13081 gatttgtttt gaaatcttcc gccctggatg aatatcgatc gaaaaacgtg aagtgatccg
    13141 acctgattca atcatgacgc agccaaattg gatgatccga tcttcttttg gattcgtccc
    13201 agtcgtttcg atatcaacga ctgcataagt tcttggtttc aaaatatctt cctcttctcc
    13261 tgcctctaat gttcttttga aattatacta caaagtgcag aaaaatactc tcatcgcttt
    13321 ttaaagaaaa tagacaaaaa cgcccagaca cgcaaatgtc tgggcgttta ttttttagta
    13381 taggttaatt aagctttagt aacgtttgtt gcttgaggtc cgcgttggcc ttcttcaaca
    13441 tcgaaagtta ctgcttggcc ttcttctaaa gttttgaatc cgtcgccttg gatagctgag
    13501 aaatgaacga atacatcgtt tccgttttct gcagtgatga atccaaatcc tttttctgag
    13561 ttaaaccatt ttactgtacc tgtttccata ataaaaatcc tccttgtgta tcaacacata
    13621 ttttgcaatt acttgaatgg tgtatatctg gaagatgttt atttgaaaca agctaccaca
    13681 gattaccgaa caaaaactac tcctatagta tatcataccg tttacaaaaa agctagagtt
    13741 tttcgacttt ttttattaaa aaaagttttc tcagcgatta cataaagtga aaaaccgaac
    13801 ttttttttaa aataaacgac atattgttca gttggtgttt ttttgctctg atgttctttt
    13861 ttaaactaaa aaaattattc tttctgacta cttatcggtt ctgtttcaac ggtcgaggct
    13921 ggggaagatt ctttagtagg tctgatgttc tcatggtatt tctgatagcc tatgacagtt
    13981 accagaagaa caaggcaaac caatacgacc aacgagatta gtttttcttt tttgctcata
    14041 tctatacctc ataaataaca ggatgatgtc catcatattt ctgagtatga gtaaaagcaa
    14101 aagctgcagc tgtagaatgt aagaaatgcc agcaactttc ataatcacag gtcggacagt
    14161 accaaaagta accaaatctt ggctgcaaag accgttcttc tgtttcagga atcgcagaat
    14221 caagatctgg tgtctgtaca taaacatttt tgtacagacg tgtgcctgta ataggaaacc
    14281 gctgtgtttc ttcagcaaaa actggctgac ttgttaaact tagggataga gacagcaaac
    14341 accataacag tctttttttc ataaagacct ccttatcgat aagtttttcc caattaaaat
    14401 catatctcaa gaacgcccgt tattcacatt ttgttcataa atgatgtttt ttgtatcata
    14461 atcgtcaaaa agaggtcgtg accacgtcac aacctctttt ttaaacggtg ttccagaagt
    14521 agcttcttcg gaaataagcc gaaatttcac aaaaatttga gaaataattt ttgtcaatct
    14581 cttcttattt cttgaagctg accacttctg tcacaacctc ttccttaaac ggtgttcaaa
    14641 agcttgcatc tgcggtaata agcccaccaa acaaaaaata tgaagagcta tttttgcttg
    14701 ctgttcttat tacttgatgc agaacagctt tttcacaacc tctcatacac ggtgtttaat
    14761 cagctgacct tcggtattag ctcaaaaaac ggcaaaatat gtgaaactat ttttccgttt
    14821 gtttctctaa tactcaggtc aaaacactga tttcacaacc tcttttaata acgaagaatc
    14881 gctgtcagac tcttttcatc tggcgcatct ttttgatcca aaataaacac ttttccgcca
    14941 ttaatgatca catcatctgc taatgcattc aacacttgac gccgatcata ttctgtttca
    15001 ggatcttcac cgaaaccatc agctaagttt gacgtagcga taaataaatg tgacactttt
    15061 ccttctttcg cagctggaac gatatcaact aactgatcga tgaatttctt atctaagagt
    15121 ttattgtatt cttttgattc ttgagctgcg agttcacttg acagcttctt cgccccttct
    15181 tcgatatctc taaaggatag ctgcgcagga gaagcagaaa tcgcaacgtc tgcacaataa
    15241 tagggatttt tagcaatttt tttgaacatc gtctgatttt ctggtagagc aaataaataa
    15301 atcggccatt gttctggatt ttcgaaagaa tccttcaagt acgtatcaac tgcttggtaa
    15361 tagttgaccc aatcgatctc tacttcttca tcttttggat ttacgccatg gaaagttact
    15421 ccatctcggg ctccgcctcc tccattagaa gagaagttca aaccgccacc tgtcagttca
    15481 gatcccaatg cagtaacgac atcaaccggt gccccttctg gtagagatac ttcttttact
    15541 tgtttgttgc tgacttcata caatttcatg gagtcgcggt tcaatcccaa taaataataa
    15601 gaatagttga actgcccatt tttgataata gccagtaaat aaggaagatc acttacatag
    15661 tattgatcgt ctaccgggat actcaaacga tggatatagg tttggtcagc agttataatg
    15721 accgctacac tcgtagttgc actacgccaa aacgaaggat ctcctaacaa attttcaatt
    15781 ttttcttgga acggggacca gtcatgttcg gaatattttt tctcaaaacg tttctttgct
    15841 tctttcgcaa aatttttgaa tttgatctga tctttttcca catcttgatg ggcgacatgc
    15901 gtattcagca tgatcgtgac gaatggtcct ttagcgcctt ctgaagtcaa ttgtgacaat
    15961 aattctttat ccttttttgc cataaacgta cccctcctaa aaaaatcatt cctttgtttc
    16021 tatctaaagt ctaccacaac actatttttc catacaataa aacgtatcta aaaaaataaa
    16081 acggtttcta cggttttaaa tttagctatt tttttaagtt atcttcataa tttcctcaat
    16141 tatttagccc cagtcttcaa ctattcttca tgaaatgctg ataaactaag aaaaagaata
    16201 aaagaggtgg atcttatgca tttgattatg attttcagtt tattaagtat tatcagttta
    16261 tttgctttca gcgcttcccg cttattagat gcggaaacac agcctattcc tgtaaaagta
    16321 cgtaaaaacg accgctaacc ttccataacg tgcgttctta tcctaaagtt ttttcagaaa
    16381 cattgaaact ctctcccctc tctgataaaa ttttaatttg tagcgaaaca aattaattac
    16441 aaggagatcg gatatgtcca taaaaaaaac acgtctagtc ctattattgg ctagtctcat
    16501 tctttgcctt gcttcttttc taccagctgt tgctgtgcaa gctgaagata ctttcaaagt
    16561 aaatgcaaaa gcagcctttg ctgtagatgc gcaaagcggt aagattcttt atgatcaaga
    16621 tggagaaaaa accatgggga tcgcttcaat cacaaaaatc atcggtcttt acatcgtcct
    16681 tgatcaagta aaagaaggga aactatcatg ggatgataaa gtttcaattt cagattatgc
    16741 agaaaatttg agtgtcaccc cagatttatc aaatgttcct ttgcataaag aaaacaccta
    16801 caccgttaaa gaattattcg actctgcaat catccagtca gccaacgctt caatggttgc
    16861 cttggcagaa aaaatctctg gcagcgaagc aaaattcact gaacgaatga aagaacaatt
    16921 gaaagattgg ggtatcaaag atgcaacgat cgttaatgca tcaggactga ataactctta
    16981 tcttggcgaa aaccgaccag aaggtactgg agaaaacgac gaaaatcaaa tgtctgctca
    17041 agatgtggct atcgttgccc gtcatttgat cttggatttt ccagaaatac tggatgtatc
    17101 tagcactacg acacaaatgt ttggcgaaaa cacgcaatca ccagtagaaa tggtcaactg
    17161 gaactggatg ctcccaggat tcgtgaatta taaagaaggc gtggacggat taaaaactgg
    17221 tacgactgaa cttgcaggag cctgtttcgt cggtacgatc actaaaaacg atcaacgaat
    17281 catcactgtc gtattgaatg cagacggcca tgcggaaaac ccaagtgccc gtttcaatga
    17341 aacagctcgc ttaatggatt attgctacga caattggtca gaaaaagagc ttggaaaagc
    17401 caatgcaagt atccctagtc taaaaaccat tgatgtaaaa gacggaaaag aatcaacagt
    17461 gcccgttgtg cttaaaagtc ctgtaaaagt atgggtacgg aacgatatgg atactggaaa
    17521 attaacaatc acaccaactc ttgacaaaaa acaagtcact gacaatgaga tccaagcacc
    17581 tatggataaa ggaacaaaaa tcggtaccgc aacgatcacc ttggcagaag ataaattagg
    17641 ttatcttgaa gacaacaacg cgccatccac agaaatcatc acggataaaa ccgtagaaaa
    17701 agcaaatatt ttcgttattg gctggcgacg cgtcgcagaa tttttcggta acttgtttta
    17761 attgaacaaa aagaaaaaag catctttcca tgtggaagat gtttttttgc tttttctagt
    17821 ttaaataaca gcttttttca tctattttcg ttatactgta taagaaaaag gagttgaatt
    17881 tatgaatcta accagagatc tgattttttt ggttctctat cttattgggg tattctccat
    17941 cgtttattgg cgaaaacaga aaaaggatcc ttccttgttc ttttacagca gtacatggac
    18001 gtttgcggta atcttgactt attttgtcgt gttggaaatt ttttattcga ccttttattt
    18061 tttgattccc ttagtgtttt tcagtatctt tgccttttcc tatttttcag aaaagcgaag
    18121 gctgttgaat ggtcttttat tcaatatttt cctcattagt tttggtatct acttgtttgt
    18181 cttgctatac gaaacacaaa atatttttct tggcggactg attgccttga tcacgatccc
    18241 gttactgctt gtctttctat tcggcattta tggattgatc gtttttcttt tttggaacgg
    18301 tgtcacagtt ttacgtagag agtcgcattc attagctaat cttttaacgt tgatactagc
    18361 catttttctt acattgtttc ttgtttttga ctttttcttg ttaaaatatt taccacaatg
    18421 gataaatgct ttgtttttct gcatcccatt gatcttgatc tatctattta tcgtattcta
    18481 caactttttg actgtctcat tcttgtatca gttcaaccgc cctcgataca accaagactt
    18541 catcgttgtg ttaggcgccg ggttgatcaa tggagaaaca gtttctcctc ttcttgccaa
    18601 gcgaatcaat aaggcgattg ctttttattg ggcacaaagc cgtgcgacat taaatccgcc
    18661 tatcctatta atgtcgggtg gacagggagc agacgaaaaa gtaccagaag caatggcgat
    18721 gaaacaatat gccatggaac aaggaattcc tgaaagagat attcttgtcg aaaccaattc
    18781 gacaaccact ttggagaata tgcgctattc aaaggaaatc atggatcagc aaatgaaagg
    18841 tccctatcgc gcgatcttca gttccaacaa ttaccacatt ttcagagctg gtctctatgc
    18901 acgacaagcg aaactgaagg caaatggcat tggggcaaaa acagctttct attacttgcc
    18961 taacgcgttt ttaagagaat acatcgccat cttgatgatg aacaaaaaaa gacatatgat
    19021 catttgcgga ttgcttttcg caggttccgc attcttatca ctgatcactt tacttttcta
    19081 aaaaaacaag gtgtgacaaa acatatgtca caccttgttt ttttctttta ttctcttgac
    19141 gattggcaag aatagtattc cttttttgac ggctacttgc tgtgcagaat aaataccgct
    19201 gtttcctgaa cacataaagc tgatcaagca gatcataaag aagtaagcag cagcttgtga
    19261 accaaataat tcgattccca tcacaaaaca ggcaatcggt gtatttgtcg caccagaaaa
    19321 taccccgata aaacctaatc cagcaagaaa aggaacagaa acatggagca aaggcgctag
    19381 tactgcgcca agcgttgcac caatctcaaa tagtggtgtc acttctcccc cttggtaccc
    19441 cgcacctaaa gacaagaccg tgaagaataa tttcccaata aaatcataag catgtgcctg
    19501 tccattaaat gattcctgca gtaacggaag actcaaccca aggtaacgtt gtgtttgcaa
    19561 aatcaacgct gcggctacaa ctactgctcc acctatcgta tttcgccaaa caggatgagg
    19621 aatccattgc gcataccgcg cttttaaaaa gacgatcgaa cggctgaata cccaaccaat
    19681 caaaccaaaa gcaatcccag caacaaaaac tttgaagaac agcaacatac tccattcagg
    19741 aatcacaccc atttggtaat gtagatgaga aacaccatag ctttctgtca tgaaatttgc
    19801 aaaaagcgca gcaaagaagc taggaaatat tgcttctgtt cggactttac cgattgccaa
    19861 cacttctaat ccaaataatg ttccagctaa aggtgtgcca aatacagaac taaaacccgc
    19921 actgattcca ctgataacca aaatctcccg ttctgcttta tccaatcgga ataaatgcgc
    19981 tatattatca gctaatgctc cccccatttg aactgctgtt ccttcacgac caacagatcc
    20041 cccaaataaa tgggtagtga tggtcccaaa caaggtcaat ggaatgagcc gcaaagggat
    20101 cttctcttct cctccattcc cttgatcgat cactaagtta ttcccacgac tagaaagacc
    20161 gccatgatac gcataaagat aagcaaaaag cgcgccgctg actggcaata gataaagtag
    20221 ccaaggatgt gctagtcgga tatctgtcac gaacgtcagg ctatttaaga aaaaagcaga
    20281 caagctcccc atgaatactc cgagaatcgc tgtgaccacc agccacttca acatgtacat
    20341 caaaatacgc actggactcg gtaattgttt ttccataaaa aattcctcct caaataaaaa
    20401 aacgcctact aaagaaaggg gctggcccca gactttagta ggcgtcatta gctatcttac
    20461 gttagcattt aaaggcgaac accatcacct attcacttcc attaaaagat agcatatttt
    20521 tctgtaaaaa acaataaaat tatcgttatt tctttacacg ttcagcaaat tcatagaaag
    20581 gagccaattt cgttaactgt tgattacatt gatcactatc atgacaaata taattcccct
    20641 ttttcgtata cgtgccatca gaaccggctt tcgttgtaga aagaaagagc gagacattcg
    20701 atgttttctg acagatcgca cagattccct tattaatcgt tggtgataaa gtaccgctga
    20761 tcccttttaa ttttccatct tcgtaataaa ccatgaattt tttttgcgtc cctggatcat
    20821 tccaaccgat gtacgtatgt gcttgcaagt cgatttcatt ccaagcgggt tgtttgagtt
    20881 ttttcacttt tcggaataat ttctcgattt gtggtttgct cggctgcata aacggctgga
    20941 cgatttgctt cagctcctcc aatgctcgtt ctgcttgcgt ttttgtcagt tttacatcta
    21001 aaactgtcgt taaaaacgta tcgatttctg atggttcgta acctaataca tcgcgaatct
    21061 tttcagctgc tagagcctga accgtttgta ccgtttttga gtcattgaca gatgagtacg
    21121 catttaataa ctgctctact tctcttttta taaaaaaata ttgatatggt ttcattgttt
    21181 gttccatgat tttaaagtcc tttcttctaa ccaaagtgca tactttgtag aaaaaagtga
    21241 tcttctgcaa agtatgtgtt acctgaagat cccggactct tttaaataag atacgttttg
    21301 catcttatca tcaccccctt taatgttcat tcttctatgt acatgattca ttcgataaat
    21361 aaaagtaaac cgtatcttga gcagatagtc aactgcaaac agaaaaagga ctgtgacaaa
    21421 agtcgtgtca aagtcccttt ctacaaacaa acggtgttcc agaagtagct tcttcaaaaa
    21481 ataagccgga atttcacaaa aatttgagaa gcaattttcg taaattcctt cttatttctt
    21541 gaagctgacc cacttctgtc acaacctcaa tatggtctat tattggtttt acctgttaaa
    21601 tcgaggattc ttttccgaag taacgttgcc atctcttacg catacttgct gacataggct
    21661 gagcggcttc tttgactgcg cagtatttgt ctacgaatgt tacgatatat ccttctttgt
    21721 acttaggcgg tgcaatcgtt gcgccccaca tgtgcttcaa aatgatatct cgctcaagat
    21781 ccgacaaatc ggtgatcttt tctgcattct ttacagcgat tcttggatgg atatacgcat
    21841 gtgtgccttc atcaaatttc gtcgtacgcc aatcatagta gaacagatca tgcaaaagtc
    21901 cagcacgcgc tgttgcttta gcattgccac cccatttttt tgcgagcaga taactatagt
    21961 aagaaacact gatggaatgc tccaaacgag tggaatgaac atgctgtgtg taattcgcta
    22021 attttttcac tgcttctgtt tctaaaagat cttctacata agacatatat tcttcgtctt
    22081 cacgccattt ttctgtcata attatcgatc tgccaccttt ttgaatttca ttttcttctg
    22141 aaattgatct aagtatacca ccagtgttcg gattattcta gtcgccttgg ataaaatagc
    22201 caaagcttaa tagttcctta atcataaaga aaaatgataa agaacaatcc ctgccgcaac
    22261 cccaacattc aacgattccg catttccttt catcgggata tatacgttct gatcagtcaa
    22321 agacaagatt tcctgactta ccccctgacc ttcgttcccc atgattattg cgaagttatc
    22381 tgatttttct actttgtcta aggcgtgtgc ttcttcattt aattctgtgc catacactgt
    22441 aaaccctttg tctttcatta aaggaatcac ttctgtcaaa tctttttgca acacaggcaa
    22501 atgataattg cttccctgca tgctgcgcag cacctttgta ctataaatat ctgccgttcc
    22561 tttgcctaat aaaacaccag ccatatcaaa tgcatctgcc gtacggatca tcgtccctac
    22621 atttccagga tcttgtacat tatctaataa cagccatcct cctgaaaaat ctggcgtgcc
    22681 ttcagccgtt aacgccatca ctgctaagat tccttgtggt gtaggtagat ccgatacagc
    22741 atccatgacc tcatccgaaa ctagaaaagt agaaatctct ttgtttgcgg ccagccagtc
    22801 tccccattct ttcatgcctc gctgtgtcac aaaaagttct tttatttctg catcagacga
    22861 cgcagcttct tcaatcagat ggaacccttc caaaagatat tcttcctttt cttcccgata
    22921 tttcttttta tgtagttttt ttaattcttt gattcttgga ttttttgctg attggatctc
    22981 tttcacattc ctcacctccc catgattata tcatggaata ggtgcttgag cttgtttcat
    23041 cctaaaaaaa tcggtatcat taatttataa aataggaaag aaaggtgacg aacatgcgca
    23101 aagttaaaat gaacgtccaa ggacgcgtcc aaggcgtagg atttcgctac atgaccaaga
    23161 tggtcgctga tcaactaggc gtgactggaa cggtaaaaaa cgaagatgac ggctcagtca
    23221 cgatcgaagc aatcggcaat gacgacatca tccagaaatt tattgaagaa gtcaagaaat
    23281 ctccgagccc aagtggacga gtgcagtatg tggatgtcca agaagacccg atgattgagg
    23341 aacgaaagaa atttgatgtg gtgggataag gttgtgaaaa agctggtctg catcaagcat
    23401 taaggacagg ttgtgaaaaa tagctctcca tatttttcaa caggctggac ttaatgccgt
    23461 agatgcaagc ttttgaacac cgtcaataag gttgtgagaa agtcgcttag ttttgagtag
    23521 taaggagaat tttgtgaaaa tggctttcca catttttgca taaaatttga cttaataccg
    23581 agaaactgac ttttgaacac cgtcgataag gttgtttttg agacgctttg cctcaagtat
    23641 taaagatagg tagtaaaaaa gctgatctat aacttgcaat aaatttgctt aacccatatt
    23701 ttccagacag aacaaaaaag tttttagttt tttaaataag aaagaaacac ttggaatcac
    23761 tcttttcttt cc
//
LOCUS       DACGEU010000040        23359 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.040, whole genome shotgun sequence.
ACCESSION   DACGEU010000040 DACGEU010000000
VERSION     DACGEU010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23359)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23359)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23359
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.040"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            139..996
                     /locus_tag="IXR40_001488"
     CDS             139..996
                     /locus_tag="IXR40_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HAQ4361343.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQTENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            1111..2031
                     /gene="pstC"
                     /locus_tag="IXR40_001489"
     CDS             1111..2031
                     /gene="pstC"
                     /locus_tag="IXR40_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HAQ4361344.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            2031..2915
                     /gene="pstA"
                     /locus_tag="IXR40_001490"
     CDS             2031..2915
                     /gene="pstA"
                     /locus_tag="IXR40_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HAQ4361345.1"
                     /translation="MNAKRSDKIATGVLYIVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            2930..3736
                     /gene="pstB"
                     /locus_tag="IXR40_001491"
     CDS             2930..3736
                     /gene="pstB"
                     /locus_tag="IXR40_001491"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HAQ4361346.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            3752..4510
                     /locus_tag="IXR40_001492"
     CDS             3752..4510
                     /locus_tag="IXR40_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HAQ4361347.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGINLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            4523..5200
                     /gene="phoU"
                     /locus_tag="IXR40_001493"
     CDS             4523..5200
                     /gene="phoU"
                     /locus_tag="IXR40_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HAQ4361348.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            5438..5737
                     /locus_tag="IXR40_001494"
     CDS             5438..5737
                     /locus_tag="IXR40_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361349.1"
                     /translation="MQKKISIITIFFICVLTSWVIQHQAALYEVPVIEIEKVRIKEDH
                     QLITGRLMNTDQKGESIYLSVPYQKNQIETANIKARQMYLVQMHGDEWQLVAKKK"
     gene            5763..6470
                     /locus_tag="IXR40_001495"
     CDS             5763..6470
                     /locus_tag="IXR40_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HAQ4361350.1"
                     /translation="MSIGAMLLIGGKQGLFALGSLIINIVLLLLLLLIFTKTEGISLL
                     NISILFVVIGMIISILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNHWKDQGLRYE
                     ELNYLTRPYRSVFLSSVLIGTAGGTLDTVITVIATLEELTKRQPEITAKQLWLSGRQV
                     GRDVIGSMTNILLFVYISGSVPSLLLYLGNQWSFKETIEQHLSLEFLRVIAGSLGIVL
                     SIPISVLFFLTVRRLKR"
     gene            6467..7234
                     /locus_tag="IXR40_001496"
     CDS             6467..7234
                     /locus_tag="IXR40_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HAQ4361351.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTSVELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALLVLPLTCVTTAYLFTKKKEQLKME"
     gene            7334..8902
                     /gene="liaX"
                     /locus_tag="IXR40_001497"
     CDS             7334..8902
                     /gene="liaX"
                     /locus_tag="IXR40_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HAQ4361352.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDGEITQVQL
                     STTTGSIYLKDTDK"
     gene            9202..9519
                     /locus_tag="IXR40_001498"
     CDS             9202..9519
                     /locus_tag="IXR40_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HAQ4361353.1"
                     /translation="MKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVAF
                     GSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTREQTKKRKEAEKIDDDEW
                     SDF"
     gene            9519..9869
                     /locus_tag="IXR40_001499"
     CDS             9519..9869
                     /locus_tag="IXR40_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HAQ4361354.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALLVAILM
                     SLVNVIVSEHNSRK"
     gene            10036..10974
                     /locus_tag="IXR40_001500"
     CDS             10036..10974
                     /locus_tag="IXR40_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HAQ4361355.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            10989..11819
                     /locus_tag="IXR40_001501"
     CDS             10989..11819
                     /locus_tag="IXR40_001501"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HAQ4361356.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLFLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            11863..12888
                     /locus_tag="IXR40_001502"
     CDS             11863..12888
                     /locus_tag="IXR40_001502"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HAQ4361357.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHYLPDSIQAFTNMEDAVKDADAVLFVIPTKAIRSVAKELVPKLNTKPVI
                     IHASKGLEQGTHKRISDILLEEIPAEKRKAVVVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQIMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            12903..13841
                     /gene="galU"
                     /locus_tag="IXR40_001503"
     CDS             12903..13841
                     /gene="galU"
                     /locus_tag="IXR40_001503"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HAQ4361358.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYILSLGKKLEAEGSKIDHNPKGITEIKEEKKK"
     gene            13966..14406
                     /locus_tag="IXR40_001504"
     CDS             13966..14406
                     /locus_tag="IXR40_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HAQ4361359.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTKDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIATKVGGIGKTTAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            14409..15011
                     /locus_tag="IXR40_001505"
     CDS             14409..15011
                     /locus_tag="IXR40_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HAQ4361360.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSTELTGIAKEKAQDLSQQAGDLAGSVKQKVSESADEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDMKKPADELGSIAKDTSEDIMIDVKDAAGKAGDTVNEG
                     MSEAKPVADDTKEMMKMAKEDAKEAKKEIKDTMTDSSTNH"
     gene            complement(15079..16185)
                     /locus_tag="IXR40_001506"
     CDS             complement(15079..16185)
                     /locus_tag="IXR40_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HAQ4361361.1"
                     /translation="MNNVKINELRQWMAQHQVELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVERFDAISDILTGTDSYTDLASIIQRLQLIKTLEEKDKLIEAGKWADVAF
                     EIGFKAVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGNTKISP
                     NELVLFDLGVVWNGYCSDATRTIAYQKPTDFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLEK"
     gene            16395..17396
                     /gene="ccpA"
                     /locus_tag="IXR40_001507"
     CDS             16395..17396
                     /gene="ccpA"
                     /locus_tag="IXR40_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HAQ4361362.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            complement(17732..20077)
                     /locus_tag="IXR40_001508"
     CDS             complement(17732..20077)
                     /locus_tag="IXR40_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HAQ4361363.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLMFAA
                     LGIGIGAGYFAYLVEDTQLPTKKALQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIILSAQVEKYFSKDEIIATYLNVSPFGRNNKGQNIAGVQEAAR
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSDAYYQKAQQTIQNKGYTIHSTIDKDVYAALQNGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLIGSES
                     RVSDYATTWQEGENAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINAKITTPFKDAISSLNGNLGKA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSKARIRSANYLANLINQAY
                     QAKPDIFGTDEKFELSSDVMKKKVSGFTGQTPGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANQATKESDEKDD"
     gene            20356..21258
                     /locus_tag="IXR40_001509"
     CDS             20356..21258
                     /locus_tag="IXR40_001509"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HAQ4361364.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAYMAENGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGTEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKIIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     IAMFKAQIFDPEVFPELLAEEVIL"
     gene            21471..23246
                     /locus_tag="IXR40_001510"
     CDS             21471..23246
                     /locus_tag="IXR40_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HAQ4361365.1"
                     /translation="MLNTLKPLINQLKKKHTYFILGIALLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIRYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     IFASILVALAFKPIVKNKYLLLSFYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYSSSKKMLPWFLGLAVSFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEAKKLKERPFLLSKQEWLKLSLFLLPLVGFSIVYQWIEYKNETTYSIAAIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALDASPTFHAVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYQKGT
                     IKKKKEFYLMGSGDGKTMNDLPIVFAFLKSGYAYAWRYKDFHQGGNYSFGTQEQVEQA
                     QELLNLPLMDNWIDSSDPRTPDFQLTKTAKVANVMIKIYQVLAIPVLIASIAGILLMI
                     LGTAFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
BASE COUNT         7444 a         4142 c         4926 g         6847 t
ORIGIN      
        1 atagcataga aacttttaat gagatagttt tttttacaat tatgagaatt tattttgtta
       61 tttaatgatt ttgattcgtt ttcatcaagt aatgaaaatg ataaaataaa catactttag
      121 gattaaagga gatttctaat gaaaaaactt aaattattct taccaataat aggattagcc
      181 attcttttat caggctgttc aaagtggatt gatcgaggag aatccattac ggctgttggc
      241 tcttctgctt tacagccttt agtagaaaca gttgctgaaa cttaccagac agaaaatcct
      301 ggaaaattca tcaatgtaca agggggcgga agcggaactg gtttgtctca agtacagtca
      361 ggagcagtcg acatcggaaa ctctgatttg tttgcggaag aaaaatcggg gatcgatgcc
      421 tcagcattag tcgatcatcg agtagcagtt gttgggatca ctcctattgt gaacaaggat
      481 attggcgtaa aagacatcag tatggaaaac ctgaaaaaac tatttacagg cgagatcaaa
      541 aactggagtg aagtcggtgg aaaagatcag ccagtagtta tattgaaccg cgcttcagga
      601 agcggaaccc gtagcacgtt tgaaaaatgg gtattggacg gagaaacagc tgttcaggca
      661 caagaacaag attcaagcgg aatggtgcgc cagatcgttg ccgacacacc cggtgcaatc
      721 agctatgttg ctttttctta tgtttccgat gatgtagata cgttgaatgt taacggtgta
      781 gaaccgacag atgaaaatgt gacaacgaac aaatggacga tttgggcata tgagcatatg
      841 tacacaagag atcatccaaa aaaactgaca aaagaatttt tagactatat cttatctgat
      901 gaagtacaag ataacatcgt tggagaacta ggttatatcc ctgtttctca tatgaaagtc
      961 gaacgtgatt ggcaaggaaa tatcgttaaa gagtaatctt tacacaaaat ttacaaactt
     1021 agctaaactt ttacatgtta ttaaaaccaa attgatgttc aatttgtaca ctgagtgagt
     1081 atgttaaacc tgattaaggg ggagtcatct gtggaagatg tgaaaaaagt attattaaca
     1141 aaatcaaaac gttcaaaaat ggaacagcgt ggaaaattca tcagtttttt atgtatcgcg
     1201 ctgatcgtgt tggttgtatt atctattttt tattttgtag ctagtaaagg attggccacc
     1261 ttttttactg ataagatcaa tgtatttgat tttctgtttg gtacagattg gaatccaagc
     1321 caaatcggag caaatgggaa accaatggta ggggcattgc ctatgatcac aggttcgttt
     1381 attgtgacct ttttatctgc tatcgttgcc acgccatttg ccattggtgc agcagtattc
     1441 atgacggaga tctctcctaa aaacggaacg aagatcttac agccggtcat cgagctgctt
     1501 gtaggtattc cttctgtcgt ttatggtttt atcggtttat cagttatcgt gccttttgtc
     1561 agaagtattt ttggcgggac agggtttggt atcttagctg gtacatttgt gttgttcgtt
     1621 atgatcttgc cgactgtcac aacgatgact gttgatgcat taaaggcagt gccacggcac
     1681 tatcgggaag cttcattagc gcttggtgcc acaagatggc aaacaatcta caaagtcgtg
     1741 ctacgagcag ccgtgcccgg gattttaaca gcagtcgttt ttggtatggc tcgtgcgttt
     1801 ggtgaagcct tagctatcca aatggtcatc ggtaatgcag cattgatgcc aacaggactt
     1861 actactcctg cttctacatt gacgtccatc ttaacaatgg gaatcggaaa tacaatcatg
     1921 ggaacagttg aaaataatgt gttatggtca ttagcgctga tcttgctatt gatgtcatta
     1981 ttctttaata tcgtgatccg tatgattggg aagaaaggag agctgaaata atgaacgcaa
     2041 aacgctcaga taaaattgct acaggtgttt tatatatagt ttcggggatc atcgtattga
     2101 ttttagcagc tttactactt tatatcttag ttcggggaat accgcatatt tcatggtcct
     2161 tcttgaccga accttccaaa gcctaccaag aaggcggtgg aatcgggatc cagctattta
     2221 actcgattta tttgcttttg atcacgatga tcatcagttt tcctatttct ttaggtgcgg
     2281 gtatctatct ttcagaatat gctggaaaaa actggctaac agatgtgatt cgcacgtcga
     2341 ttgaaatctt gagctcgttg ccttctgtcg ttgtcggttt attcggtttc ttggttttcg
     2401 ttattcaatt ccagtatggt ttctcgatta tttctggtgc attggctttg actgtattca
     2461 acttgcctct tttgactaga acagttgagg agtctttaca agcggtccat tacacacaac
     2521 gagaagcagg attggcctta ggtttgtcac gctgggaaac agtgataaaa gtggtggttc
     2581 cagaagcgac accagggatt ttgactggtg tgatcctaag ttctggaaga atttttggtg
     2641 aagcagctgc attgatctat acggctggac aaagtgcacc tgcgttagat tttacgaact
     2701 ggaatccatt aagtgtttca agcccgatca gcattttccg tcaagctgaa acattagctg
     2761 tccatatttg gaagatcaat acagaaggca cgatgcctga tggtgtttct gtttcggctg
     2821 gcgcttctgc cgtgttgatc attgctgttt tactgttcaa cttcggcgct cgtgcgattg
     2881 gcaaacgatt ataccgaaaa atgacttcag cctaaggaga agaagcaaaa tgaaaaaata
     2941 taactggaat gaaacaaatg tcatcaccat gccaaaagag aaagaagtag cactatatac
     3001 ggatgatcta catgtctggt atggcgacaa tgaagcaatc aaaggagtgg atctggaatt
     3061 tgaaaaaaat aagatcactg cactgattgg tccttccggc tgcggaaaat ctacgtatct
     3121 tcgttcgttg aatcgaatga atgatgggat cgctaatacg aaaatcactg ggaaaatcat
     3181 gtatcaaggc gtagatatta atgcgcctca agtggatgtt tatgagatgc gcaaacggat
     3241 tggcatggtt tttcaacgtc ctaatccgtt cagcaagtcg atttatgaca atattacatt
     3301 tgctttgaaa cagcacggcg aaaaaaacaa aaagaaatta gatgaaatcg ttgaaacaag
     3361 cttgaaacaa gctgccttgt gggaccaagt aaaagacagc ttggacaaaa gtgccttggc
     3421 tttatctggc gggcaacagc aacgtttatg tattgctcgt gcgatcgcga tgaaacctga
     3481 tatcttgctg ctagacgagc cggcaagtgc tttggaccct atttcgacag gaacggttga
     3541 agaaacactt gtaaacttga aagaagacta tacgatcatc atcgtgacgc ataacatgca
     3601 acaagcagct cgtatcagcg actatactgc ctttttctat ctaggaaaag taatggaata
     3661 tgacaaaact aacaagatat ttaccagacc aaaaattcag gcaaccgaag attatgtgtc
     3721 cggtcatttt ggttaagacg gaggcctcaa catgacaaaa gaaattattt catctaaaga
     3781 tcttcatctg tattatggaa agaaagaagc actaaaaggg atcaatctaa gtttcaatca
     3841 aggggaaatc actgcgatga tcggtccttc tggttgcggg aaatccactt atctgcgttc
     3901 tttgaaccgg atgaatgacc tgattccgaa tgtaacgatc accggaagtg ttttatataa
     3961 agacaaagac atctatggtc caaaaacaga tgttgttgaa ctaagaaaag aaatcggcat
     4021 ggtattccag cagccaaacc catttccttt ttctatctat gaaaatgtca tctatggatt
     4081 gaaattaaaa ggggaaaaag ataaaaaagt ccttgatcaa gtagttgaag aaagcctgaa
     4141 ggcagcgtct gtttgggatg atgtgaaaga caaattgcat aaaagtgctt tatctttatc
     4201 cggtgggcag cagcagcgtg tatgtatcgc acgtgttttg gcagttaatc cggaaatcat
     4261 cttattggat gaaccaacaa gtgcgcttga tcctgtttct actgggaaaa tcgaaagtat
     4321 gctgttagaa ttaagagagc ggtatacgat gatcatcgtg acccataata tgtctcaagc
     4381 ttcacgtatt tcagataaga cggcattctt tttagatggt cacttgatcg aatacaacga
     4441 tacgaagaag atattcatga atccagaaaa acaagagaca gaagattata tttcaggtcg
     4501 atttggataa ggaggaaacg gaatgctacg tacacaattt gaagaagaat tgctgaatct
     4561 ccataatcag ttctacgaaa tggggatgat ggtgagcagc gccgtgcaca agtcagttcg
     4621 tgcatacatc aaacacgata aaatcttagc ccaagaagtt atcgaaaacg atataaatat
     4681 caataacatg gaaacacgct tggagaagaa aagttttgaa atgatcgcat tgcaacagcc
     4741 agttacaact gatttgcgta tgatcattac ggtcatgaaa gctagctcgg atttagaacg
     4801 tatggccgat catgcggtgt ctgttgctaa atccacgatt cgcgtaaaag ggcagacgag
     4861 aataccggaa atcgaaaaag agatctccga tatgtccgat tatgtgaaaa aaatggtgga
     4921 caacgtccta gttgcttatg tcaaaacaga cgaaaaagac gcacgtacga tcgccaatat
     4981 ggatcaaaga gtcaatgact atttcaatcg aatctataat gcaacaatca aaaatatgca
     5041 ggaaaatcct gagacagtca tcagtggaac agactacttg aatgttgcca gttatctaga
     5101 acggatcgga gactatgtga caaacatctg tgaatggatc gtctacttgg ctacagggaa
     5161 aatcactgag ttaaatacga accacaatga gattttctaa actgaagctg tgattatgcc
     5221 gtttgtttag gaaaagaggt tgtgaaatca gcggttgtga aaaagctgtt ctgcatcaag
     5281 taataagaac agtcaaacaa aaaatagctc ctcatatttt tcgtttggct ggacttatta
     5341 ccgcagatgc aagcttttga acaccgttta ttcgggaaag ggtttgtgac aaaacatgtc
     5401 acaaaccctt ttcatcattt catagaaagg ataaagaatg caaaaaaaaa ttagcatcat
     5461 cactatattt tttatttgtg tgcttacttc atgggttatt cagcatcaag ctgctttata
     5521 tgaagtacct gtcatcgaga tcgaaaaagt acgaataaaa gaggatcatc aattgattac
     5581 aggaagactg atgaacacgg atcaaaaagg agaatcgatt tatttatcgg ttccttatca
     5641 aaaaaatcaa atagaaacag caaatataaa agcgagacaa atgtatctag tccaaatgca
     5701 tggagatgaa tggcagctag tagcaaaaaa aaaatgatgg ctggcttttc ttcttcacaa
     5761 gtatctccat tggcgccatg ttgcttattg gcggaaaaca gggtctattt gctttaggaa
     5821 gtctcatcat caatatcgtt ttacttttac ttttgttgct catctttact aaaacagaag
     5881 ggatttctct attaaatata tctatcctgt tcgtcgttat agggatgatt attagcatat
     5941 tggctttaga tggatggaat agaagcagta taatcaaaat ttcagctgca gttacgagtg
     6001 tttttttagc attttttatt tgtcttttga caatgaatca ttggaaagac caaggactgc
     6061 gctatgagga actgaattat ctgacacgac cgtatcgttc tgtttttctt tctagcgtac
     6121 tgattggaac agctggagga acactcgata ccgttatcac agtcattgcg acattagaag
     6181 aattgactaa gcgacaacca gaaataacag cgaaacagtt atggctttca ggaaggcaag
     6241 tgggtcgaga tgtgattggc tcgatgacca atatcctttt gttcgtctat atcagtgggt
     6301 cagttccatc gcttctttta tatttaggaa atcaatggtc gttcaaagaa acgatagaac
     6361 agcatttatc attggaattt ttacgcgtca ttgctggcag cttaggaata gtattatcga
     6421 tccctatctc ggtcctcttt tttctgactg taaggaggct gaaacgatga atgtacttat
     6481 tatacttgtt gggattttag caatcagcgt gctacttatt ggcggtacgc aaggtatgta
     6541 tattctttta ggcttattca tcaatttagg gatctttttc ctgttgttat tcggttatca
     6601 tcagaagtgg ccgatactgg cattgtcggt cataggattt ttattgattg ctgtggttat
     6661 cttatttttt atcaacggtt ataatctaaa aatgcgtgca gcttttgtga gtatactgat
     6721 ctttttattt tgtttcctac tattgcttcc tatcactgat tttttagcga tccaaggttt
     6781 tacatcggta gaactagaag aattatctgg cttagataag actttagcga ttgattttag
     6841 attacttacg agatcgttgc ttctgattag tcttagtggt gctgttttag atgctagtgt
     6901 agcaatttct agtgggacat tcgaagtata tcaggcaaat ccgcaattat ctttttacca
     6961 attgcgccat tctagtttcg ctattgctaa aaaaatattg gcgtcaacag taatgacact
     7021 tctttttgca ttcatgggaa gttctttagc gttgatcctc tggtttattg atttagacat
     7081 tccttttcag caagtgatca atgaaaaatc atttgttcta gaatatacga tggctattct
     7141 taccacattg tctgcactac ttgttcttcc tttaacctgc gtgactacag catatctctt
     7201 tacaaaaaag aaagaacaac tcaagatgga gtaaaagtta caacttaagt cctatgacat
     7261 ttttactgaa tcagtgcata atatggatgt aaggaaaagc ttgcaaacaa ttttgcttaa
     7321 ggaggcaatt tccatgaaag aaagagaacg tattttagat ttagtgaaaa aaggaatcct
     7381 ttcgactgaa gaaggcttag atttattaga aagcatggca actgaaaaag acgaaaagca
     7441 aataaaaaaa gaagcagaca aggtaactgc tagtcataaa gaaaaagatc aggcaagtca
     7501 attgatcgat aaacttgaaa acggcgaaga agaaatttct gagccagttg atccaaagga
     7561 aagagaaagg caagatcaag aaaacttaga aaagatctta gatgaactag caactgaagc
     7621 gaataaaact tcggcgcgtc tagatgaagt aaatgctcaa ttcgctgaca ataaggcagc
     7681 acgcaatgag aaacaggaag cattgatgca gctgaataca aaagaagaat taggcgagtt
     7741 gacagaagaa gaattagcac agcgtcagac gttagaagca gaaatcaaag aattagaagc
     7801 tagtggcgat acactgttag aagaacaatt gaaattagaa gcagaattaa aagatatccg
     7861 taagaatcaa tggtctgaga aaaaagaaac gtttactgat aagtttgaat tgccagatga
     7921 ttggaaagat caagcaacag atacactgaa tcaagtaggc gaaaaaatgt cagaagctgg
     7981 atcacagtta ggcaaattct tgaagaaaac attccaaact gtttcagaaa cagtgaatga
     8041 caacatggaa tggaaagatg tcagcttacg tgtccctggg attgcgacaa cgaaatttga
     8101 gcatgaattt tactatgaag ctcctgcagc aagtatcctt gatatcaagg cagcaaacgg
     8161 aaacgtgacg ttaaaaacgt gggacagcaa cgatgtgaaa gttgaagcta agatcaaact
     8221 ttacggaaaa atgggtgctg aaccatttga agcattctct gaacggagcc agattgaggt
     8281 taatgaagat catatctcct tccaaattcc aaataaacgt gtgcgtgcag accttgtttt
     8341 ctacttacct aaacgagtat acgaccacgc agctattaaa cttctaaatg gcaacatcat
     8401 gattgaaaca ttggaagcta aagatattta tacaaaatct acgaatggta acatcatcgt
     8461 ggaccaatta actgcaacga tgctggaagt agaaggtgta aacggcaata tcgatattcg
     8521 aaacgggaac atcttagatt ctattatcga aacagtaaat ggtacagtga catttggtgc
     8581 gacagcagaa aacctttctg tgtctttggt aaatggtgat gtacgtctta cgattaaaga
     8641 agataatttg aaaaaagtag aagcaagttc agtgaacgga aatgtcaaag tcgctttacc
     8701 agatggcatc ggtttggaag gacatgctaa aacaagtctt ggaagtatca acagccgtct
     8761 gtccaattac gaagtagttc gtgagaaaaa agaacggaca aaccaaatgt tgcaattccg
     8821 tcgtgtttca gatggtgaaa tcacgcaagt gcaactttca acgacaacag gaagtatcta
     8881 tttaaaagat acagataaat aaagaggttg tgaaagagat gttcagcctt gagcaataag
     8941 aagcgatttt gtaaaatagc ttcccctatt ttacaaaatt gtgccttatt gccgataggc
     9001 tatctcttga acaccgttta ccaagagatt atgaacctgc caattatcgc cgagtcacaa
     9061 ggaataattt cagaaaaagc tcgtcacgtt ttatgaatat ggtaatttgt gaccgagaat
     9121 tttgcagaaa gacaccgatt aagaagaagg ttgtcacaac gattttcttc atttaaaata
     9181 gtagaacaga ggtgagacat gatgaaaaaa aagttgacaa aatccaataa aaatgttgtt
     9241 ttgacaggga ctttagcagg aataggagaa tacatcggga ttgatccgac tgttatccgt
     9301 gtgctttatg tattcctgag cttagttgct tttggaagtc caatcatttt atacatttta
     9361 ttagctttga ttatcccatc tgcgcgttct gcacgaacaa actatggaca taacaatgca
     9421 tattatgaaa aaaacaatta tcgtgaacaa actcgtgaac aaacaaaaaa acgcaaagaa
     9481 gcggaaaaaa tcgatgatga cgaatggagt gacttttaat gtcgtacttt caacgtattt
     9541 tagttaatac gttaacattc atatcattgg ctgttctttt tcctgcgatg gtccatgtga
     9601 gcagtatttg gacggccgtt cttgccagct tcgtattgtc tgtgttgaat atgtttgtca
     9661 aaccgatttt gacgatactg tccctgccct ttacattagt cacattggga ttgtttacgt
     9721 ttgttatcaa tgcagcgatt cttaaaatga cctccttttt tgtgggagca gaacatttta
     9781 gtttttcttc attcggtgca gcgttgttag tagctatctt gatgtcgctt gtcaatgtaa
     9841 ttgtcagtga acataacagt agaaaataaa agaaagctgt gccgaactat cggcgcagtt
     9901 tttttattta gaatcaggaa tgcgttttct attacattgg taattaaata aaaacgtttt
     9961 ttttaattgg tagtactttt ggctagacaa tgataaaatg atagagaaca ctctaataga
    10021 aatgaggtag catgaatgtc agaagttgta aaagttagcc aattagtgaa aaaattatct
    10081 ttggaaatcg tgacaggcga cgagaaaagc ttagaccgtg tcatcgtaac tggggacatc
    10141 tcacgcccag gactagagtt gactggttat tttaattatt attcccataa tcgtttacag
    10201 ctatttggca gtaaagaaat cagttttgcg gaacggatga tcccagaaga gcgtttgatc
    10261 atcatgagaa gattatgtag tgaagatatg cccgcattta ttatttcaag aggattaccg
    10321 gctccagaag aaatgatcca ggcagcaaat gaaaatggga tagctgtact gcgttctccc
    10381 atctcaactt ctcgtttatt aggagaatta tccagttatt tagatggtcg ccttgcccct
    10441 cgaacaagtg tccacggtgt tttagtggat gtttacggat taggtgtact gattcaaggt
    10501 gacagtggga taggaaaaag tgaaacagcg ttggagttga tcaaacgcgg tcatcgattg
    10561 atcgcagacg atcgagtaga tgtttatcag caagatgaat taacggtgat cggagaaccg
    10621 cctaaaatcc tggaacatct aattgaaatc cgaggaatcg ggatcattga tgtaatgaat
    10681 ctttttggtg cgagtgcggt acgtggctct atgcaagtcc agttggctgt ttatctggaa
    10741 gcatgggcaa aagataagaa atacgaccgt ctgggctctg aagacacgac cgttgaaatc
    10801 gcggaagtgg gcattccaca aataaaaatc cctgtcaaaa caggacgaaa cgttgcaatc
    10861 atcattgaag tagccgcgat gaatttccgt gcacgtacaa tgggctttga cgcaacgaaa
    10921 acatttgaag aaagattaag tcgcttgatt gaagaaaact caggcaacga ctagcaagga
    10981 gtgacaatat gttagcacaa atcaatcgag ttgcttttga gcttgtaggg attcctatct
    11041 actggtatgc attgatcatc gtatcaggta tcattatcgc catgtggctt agcagcagag
    11101 aggctgttcg ggtaggatta aaagcagatg atgtgacaga ttttatgttg tggggattgc
    11161 ctatctccat tattggtgct cgcttatatt atgttttatt tgatcttccc cagtatatag
    11221 ctgatccaat ccaaatattc aatatccgtt caggaggctt agctatttat ggcggactga
    11281 ttgcaggcgc gatcacgctg tattttttta ctaaatatca ttttatttct ttgtggactt
    11341 ttttagatat cgctgcacca agtgtattat tagcacaggc aatcggtcgt tggggaaatt
    11401 tcatgaacca cgaagcatat ggaccagaca cgacgcgaag cttcttagaa agtctgcatt
    11461 taccgcaatt catcattgat aatatgtata tcgaagggat ctatcgtcaa ccaacatttc
    11521 tttatgaatc actttggagt ttgattggat ttattttgct tttgttttta cgaaagaaac
    11581 cacacctttt gaaaaaaggc gaagtccttt tatgttatct aatgtggtat agtttcgggc
    11641 gtttctttat tgaaggatta cgtacagaca gtctttactt tttaggtgtg atccgtattt
    11701 ctcaattatt atctgctgtg ttatttgtcg gtacattgat tctatttatt tggcgcagaa
    11761 aaaaaggaaa tttaccggat tatgaccgct cattaggaaa aaatcaacaa attatctgat
    11821 ttttagagcg ttaaaaatga aaaaaatttc aggagtggta aaatgaatta tagagtagcg
    11881 gttttaggac caggctcttg gggtactgct ttggcacaag tcctcgccga aaacggacat
    11941 gacgttcgga tttggggaca tcgtgcttca caagtagaag aaatcaacac ccaacacacg
    12001 aatcaacgtt atttaccaga tcattatcta cccgattcca tccaagcatt caccaatatg
    12061 gaagatgcag taaaagacgc agatgcggtg ctattcgtca ttccaacgaa agcaatacgt
    12121 tctgttgcaa aagaactagt gcctaaattg aatacaaagc cagtgatcat ccatgcaagt
    12181 aaaggattag aacagggaac acataaaagg atctctgaca tcttgttaga ggaaatccca
    12241 gcagaaaaaa gaaaagctgt tgttgttctt tctggaccaa gccatgcaga agaagtagcg
    12301 aaacatgaca tcactacgat cacagctgca agtacagatg caaaagcagc aaaatatgta
    12361 caagagctgt tcatgaataa ttattttcgg atctatacca atcctgatgt gatcggtgta
    12421 gagatggggg cagctttgaa aaatattatt gctattggtg ctggcgctat tcacggctta
    12481 gggtttggcg ataatgcaaa ggcagcaatc atgacgcgcg gattagctga gatcagccgt
    12541 ttaggtgtag caatgggtgc caacccgctg acctttatcg gattaagcgg agtaggcgat
    12601 ctagtcgtta cttgcacaag tgttcattct aggaactggc gcgcaggcaa cttgttagga
    12661 caagggcagc ccctagaaga ggtgctagcc aatatgggaa tggtcgttga aggtgtgaat
    12721 actactcaag cagcgatgga actagcccaa ataatggaaa tcgaaatgcc catcactcaa
    12781 acaatctatg aagtgctgta tgaacaaaaa gaaatcaaaa cagccgcaaa agaaatcatg
    12841 ttacgtgatg ggaaaaaaga aaatgaattc tcattaacaa ttttttgaag gagcgaatgt
    12901 atatgaaagt caaaaaagca gttattccag cggcaggatt aggaacaaga tttttaccag
    12961 caacaaaagc tatggcaaag gaaatgttgc caattgttga taaaccaaca atccagttca
    13021 tcgttgaaga agcgttgaaa tcaggaatcg aagacatctt gatcgttaca ggaaaagcta
    13081 aacgaccaat cgaagatcac tttgattcaa atattgaatt agaaacaaac ctaagtgaaa
    13141 aaggaaagac cgaattattg aaattagtag aagaaacgac agatgtcaac ttgcatttca
    13201 tccgtcaatc tcatccaaag ggtttaggac atgccgttct tcaagcaaga gcctttattg
    13261 gaaatgaacc gtttgtcgtt atgctaggcg atgatatcat ggaagatgaa gtaccattga
    13321 cacagcaatt aatcgatgat tacgaacgta ctcatgcttc tacgatcgcc gttatgcaag
    13381 ttcctcatga tgaaacttca aaatacggaa ttatcaatcc aggagaagta ttggaagatg
    13441 ggttatacaa tgtcaaaaac tttgttgaaa aaccagatcc aagcaaagca ccaagtgatt
    13501 tagctattat tggacgttac ttattgactc cagaaatttt tgatgtattg tccgagcaac
    13561 aaccaggagc cggaaatgaa atccaactaa ctgacgcaat cgatacattg aataaaacac
    13621 aacgcgtatt tgcccgtaaa ttcacaggta aacgttacga tgtcggtgac aaatttggtt
    13681 ttatgaaaac aagtattgaa tatggtctaa cacatccaga agtaggtgca cctttacgtg
    13741 agtatatcct gtctttaggt aaaaaattag aagcagaagg aagcaagatc gatcataatc
    13801 caaaaggaat aacagaaatc aaagaagaaa agaaaaaata accctttttt ctaacgagct
    13861 tcagctgcta attgaataaa aagtagttga agctcgtttt tatttgttta aaaaacacga
    13921 aaatgctatc cttatagaaa agagagacaa gaagggagtt tgatcatgtc aggaggagaa
    13981 attgcaggat tgatcgcagc aatcgccttt gcgatacttg tcgtttttat cgttcgtgtg
    14041 ttgttgcaag tttctaaaac tttagaaaaa gtagatcaga ctgtagcaga agcaaatacg
    14101 acgatcgaaa tcgtcacaaa agacgtagat cttttgtcta gacaagtaga aggcttgctg
    14161 gtcaaaagta atgaactgct cttggatatc aatggaaaag tcgcaacgat cgatccattg
    14221 ttcacagcag ttgctgattt aagtgaaagt gtatcagaac ttaatcattc tagtaaaaac
    14281 atcgcgacga aagtcggcgg aatcggtaaa acgacagcta aagcgacggt tgccggaaaa
    14341 gtcggtggga cagcgatgaa attttttaaa aacaaaaaac atactgaaac gacaggagga
    14401 aaataaaaat ggctaaaaaa ggtggatttt tattaggtgc agtagtcgga ggaacagccg
    14461 cagcaatcgc cgcgttattg ttagcaccaa aatctggtaa agaacttcgg gatgaattag
    14521 ctgcccaagc ggatgatttg atggatatgg cttcagatta cacagatatg gcgaaagaaa
    14581 aatcgactga gttaacaggt attgcaaaag aaaaagcgca agatctttct caacaagcag
    14641 gtgatctagc aggtagtgtc aaacaaaaag taagtgaatc agcagatgaa gcaggaagtg
    14701 aatctgacga tatcttgtta aatcttaaag aacaatcagc tgacttatct aatcgtttca
    14761 aaaaaacggc agaagatatg aaaaaacctg cagatgaatt aggaagtatt gctaaagata
    14821 cttcagaaga tatcatgatt gatgtaaaag acgctgctgg taaagcagga gatactgtca
    14881 atgaaggaat gtcagaagca aaaccagttg cagatgacac aaaagaaatg atgaaaatgg
    14941 caaaagaaga tgcgaaagaa gctaaaaaag aaataaaaga tacaatgaca gattcatcta
    15001 caaatcacta aaatcactaa aatcacaaat ttatagaata aaaaggtggg agcggactag
    15061 ctctcacctt ttttactctt atttttctaa aactagtaat tcttttggtg tagtcgtgaa
    15121 tggcacacag ccatcgcttg tcacatatac acagtcttcg atacgtaccc ctactttttc
    15181 aggaatatag attcctggtt caagagagaa gcacatccct tcttcgatta ctaagtcatt
    15241 tccttctaca agggaaggga attcgtggac ggttgttccg atcccgtgac ctaaacggtg
    15301 attgaaatat tcgccgtagc catagctgtt gatcacgttt cgtgcgattt gatcaagttc
    15361 acctgctgtc acacctggac ggacggcttc ttgtgcggca agctgtgctt caagagtgat
    15421 gttgtatatt ttttcttgga agtcggttgg tttttgataa gcaattgtac gagtagcatc
    15481 actgcaatag ccattccaaa caacgccaag atcgaataac acaagttcat tcggtgaaat
    15541 cttcgtgttt cctggtgtac catgagggct tgcagcattt gctcctgcaa ggactaatgt
    15601 gtcgaaagac atttgtgaaa caccttgttt tttcaattgg tattcgattt ctgcaatgat
    15661 cgcttgttca gtcacgcctt ctttcactgc tttaaagcca atctcaaatg caacatcggc
    15721 ccatttacca gcttcgatca gtttgtcttt ttcctctaga gttttgatca gttgtagacg
    15781 ttggatgatg gaagctagat cagtgtaaga atccgttccc gtcaagatat cagagatagc
    15841 atcgaagcgc tcgacagtca aggcgttctt ttcaatccct acattgccag gctgaccata
    15901 gcgagcacga agttcttttc cgatgatctc ccaagggttt tcgctgtcta aatagccacg
    15961 gacatcatac gcccaactac tgttttgagc atcttcaact tccaaagcag gagtgaaaag
    16021 gaaaggatct tgttcaagag ggataaaaag agctagtaca cgctcatgag gatcactttc
    16081 gtatccggaa aagtaagcga tgtggccagg gtcgctgata taagccaatt cgacttggtg
    16141 ttgtgccatc cattgacgta gttcattgat ttttacgtta ttcatttggc aacctacttt
    16201 ctaaattaat tttgtattca ataattgtac cactgattta ttaaaagacc aacgttctaa
    16261 aaactgaaaa aagtaaaaat tttcatgaaa acagagataa aacggttgca attcttgaga
    16321 ttatttgata ttctatttta gaaatgtaag acgtattttc agaaaacata taaaatatga
    16381 ataggagaac acaaatggaa aagcaaacaa tcactatcta tgatgtagcg agagaggcaa
    16441 atgtttcgat ggctactgtt tcacgtgtcg taaatggcaa tccaaacgtc aaaccagcaa
    16501 caagaaaaaa agtcttggaa gttatcgatc gcttggatta tcgtccaaac gcagttgcgc
    16561 gtggcttggc aagtaagaaa acaacaacag ttggggtaat catccctgat gtcagcaata
    16621 tgttctttgc ttctttagca cgtggtatcg atgatgtggc aacaatgtac aaatacaata
    16681 ttatcttagc aaattcagat ggtaacgacc aaaaagaagt caatgtattg aataacttac
    16741 tggctaagca agtggacggc gtgatcttca tgggtcacca tatcacagac gaaatccgtg
    16801 gagaattttc acgttcaaaa actcctgttg tattagctgg ctctattgat ccagatgaac
    16861 aagtaggtag cgtaaacatt gattatgtat cagcaacaaa agatgcagta aacaaattgg
    16921 caaaaagcgg caataaaaaa atcgcttttg tcagtggtgc gttgatcgat cctatcaatg
    16981 gacaaaatcg tctgaaaggc tataaagaag cattaagcga aaataaccta ccatatagcg
    17041 aaggattgat ctttgaagca caatacaact tcaaagatgg tctatctcta gtcgatcgga
    17101 tccataatag cggtgcaaca gctgtctatg tttcagatga tgaattagcc atcggtattt
    17161 tggatggttt attagaccgt ggcgtgaaag taccggaaga attcgaaatc atcacaagta
    17221 acaattcact actgacagaa gtagctcgtc ctcgtttaac aagtatcaca caaccattat
    17281 acgatttagg ggcggtatct atgcgcctat tgacgaaaat gatgaataaa gaagaagtcg
    17341 aagaaaaaac gattatcttg ccttatggaa tcgaagaaaa aggatctaca aaataataaa
    17401 aggacaacca ttcagaggtt gtgagcctgc cgtttaactc tgcgttacaa ggagcaattt
    17461 caaaaaacag catttcatgt ttgatgaata ttgtgactcg tgattcggag ttggcaggag
    17521 aacaccgttt attcgggaaa aggggttatg acaaaatttt gtttaatcct ttttttttgt
    17581 cttaaaaaag agagaaagtg gttgaaatta catttatcgt atataaaaca atccgtgtat
    17641 agatgctgca ttatgttcac caccatcaaa aaaataaggg actgtgacaa tactattgtc
    17701 acagtccctt attactgtgt attctattaa atcaatcatc tttctcatct gattctttgg
    17761 ttgcttgatt cgctcttgca taagctgaag cggtgttcca gtaatctgta tagttttcat
    17821 cggtaccgcc aacgccaaat ttaaaggcgc ttttcttcgg tccatttttc gcccatagcg
    17881 attcaactgt ttttcctggt gtttggatgg attttttatt gacagtaact tttccaggtg
    17941 tttgaccagt aaatccagat acttttttct tcatcacatc agatgataat tcgaatttct
    18001 catcagtgcc aaaaatgtca ggttttgctt ggtaagcttg attgatcaga ttggcaagat
    18061 aattagccga acgtatcctt gctttgctgt ccattccagt attgtcatcg tgccctgccc
    18121 agctactgat ggtaatagac ggagtagaga caattagcca tgaatctcgg tattcattgg
    18181 tagaaccagt ttttccgacc caatctgctt ttcctagatt tccgtttaag cttgagatgg
    18241 catctttgaa tggtgtagtg atttttgcat tgatcacact gcgcatcatg tcattcatga
    18301 tcgatgccgt tgcttccgaa tagatccgga cagagttgct ttcgtgttta taaattacat
    18361 ttcctgcgtt atctgtgatg gaatcgatga tatagccttc ttcatagacg ccgccgtttg
    18421 ctaaagcctg aaatccattg gtctgttgaa gcgtcgtgac atctactgta cctaaaggag
    18481 cagattcaac gccccaattg tcatttgccg ggtagttcat ctttgccaag tagtgctcgt
    18541 aagcatattg tttcgatcca ccggaattca acacatcttg atataagtga taagccggga
    18601 tattgttgga ccattctagt gactcacgga cggtttggaa ggtgttcgat ccttcgttag
    18661 tagcattgac gattttctcg ccagcatttt ctccttcttg ccaagttgtt gcataatctg
    18721 atacacggga ttctgatccg ataagcccca tgtcgattgc aggtccataa acaagaactg
    18781 gtttgattga tgagccagct tgacgttctg tatcgaaggc atggttattt tgattctgac
    18841 tgtaattccg tccgccaacg aatccgtaga tgcggccagt tctgttatcc atcaatacat
    18901 ttccggtttc tacttgactg ccagcaccat catctaacat gtatccataa ttttctacgc
    18961 cattttgcaa tgcagcatag acatctttat cgattgtcga atggattgta tatcctttat
    19021 tttggatcgt ttgctgtgcc ttttgataat aagcgtcact gaccgatgaa tcagacatat
    19081 cagcgttgtc tttttcagcc aattgttgtg caatgattct tgttgcttca ttcatcacag
    19141 tataatacaa gaattctctg tcagtctgtt ctgcgatttg ttgtggtaga aagtcttttg
    19201 taaggtcata ggcttttgct tcttcgtatt gttctttcgt aatttggcct tcacgataca
    19261 tactgaataa aacaaaatct tttctggcaa ggccggcaga aagatcttct tttagcgcac
    19321 ctgtgttcgt gtatggacta tacgtgatcg ggctttgggg taatccagcg atataagcag
    19381 cttgcggcag cgtcacatct tttgcatcta caccaaagat tcctcttgca gcttcctgga
    19441 ctccagcaat gttttgtccc ttattattac gaccaaatgg tgagacattc aaatacgtag
    19501 caatgatctc atcttttgaa aagtattttt ctacttgtgc agaaagaatg atctcgtttg
    19561 ctttacgttt gaatgttgtt tcatctgtaa ggatctgctg tttgactaat tgctgtgtca
    19621 aagttgatcc accagaagag ccaataccag tagcttcaga tactaatgct cgtaaaacag
    19681 ctttaggaac gtaaccttgg tgtttatcga agtattcatc ctctgtgctg ataattgcag
    19741 ttttcaataa aggtgaaatt ttatcagatg aaatagtcgt gcgcatcaga tctgtctgga
    19801 tttttgatat ctctgtatta tctgcataaa caatctttga cgtttctgta atgtttccta
    19861 gttctgtctg cagtgctttt ttagtcggca attgtgtgtc ttcgacgaga taggcaaaat
    19921 agccagcgcc tattccaata cctagagctg cgaacatcaa aagaagaaca gtaataaaaa
    19981 cagtcaatga ttgaaaaact ctaaaaataa tcttaggaac aaaccatttt tctttttttc
    20041 ttctattctg tttttttcga gtatttttgc gtggcaaaag ggtcacctca actaatggtt
    20101 ttatttcgct aattatagca aataatagaa caaaaaaaca gacaaggctg tttttggcag
    20161 gaatttcttt tttaaaagag ttaaaacgtg agaaaatgat cttttttata aaagagttct
    20221 taagcttttc tttagagaaa atttcagtta ctatggagaa cagggcaaag aaaaatcaat
    20281 cattttcttt gtatatcatc ttaccaatat ataggaattg ttagtaacaa ttgcctttca
    20341 aggaggaatc catccatgtt attaggctca cacgtcagca tgagcggaaa gaaaatgctg
    20401 ttaggagcag cagaagaagc agccagttat ggatcttcga cttttatgat ctatacaggc
    20461 gcccctcaaa acactagaag aaaagccatc gaagagatga atattgatgc cggaaaagcg
    20521 tacatggcag aaaacggtct aacaaatatc gtcgttcatg ccccttatat cattaatttg
    20581 gggaatacga tcaaaccaga aatgtttcct tttgccgtcc aatttctgag agaagagatt
    20641 gttcgtgcgg aagctttagg cgctactcaa attacacttc acccaggtgc tcatgtaggg
    20701 gcaggaacag aagccggaat tgctagaatt attgaaggct tgaatgaagt tttgacaaaa
    20761 gaacagacgg cacaaatcgc tttggagaca atggcaggta aaggtacgga aatcggtcga
    20821 acatttgagg aattagcgca aatcatcgat ggagtaaaat tgaatgaaaa attatccgtt
    20881 acttttgaca cctgtcatac gaatgatgcc ggttataata ttaaagaaga cttttcaggt
    20941 gtaatggaag agtttgataa gatcatcggg ttagatcggc ttaaagtact ccatatcaat
    21001 gattctaaaa atccgcaagg ttcgcataaa gaccggcacg ccaatattgg ttttggaaca
    21061 atcggattcg acacgctgaa taagatcgtc catgatccaa tgtttgacaa tatttcgaaa
    21121 atcttggaaa ctccctatgt cggcaaagat aaaaagaaag cttacgcacc atatggaaaa
    21181 gaaatcgcca tgttcaaagc acaaatattc gatccagaag tgtttcctga gttattagca
    21241 gaagaagtga tactctaaga ttttctatct gacagcagca aaaaaggacc aggcacattg
    21301 ccttgtcctt ttttgtttaa gaaacaaagg agtgcttttt gcagtctttt tcatcatgca
    21361 tcttctcccc cctcttttta aatttagaca aacagggtat actggtagaa aagtaaaaaa
    21421 acgaaaagtt tcacaagcaa gtggcaaaac gtgattggaa ggacgaaaag atgctgaaca
    21481 ctttaaaacc cttgatcaac caactaaaaa agaaacatac atactttatt cttggcatag
    21541 ccctattatt tacaattatt cgtttgtatt tatatagtaa agcaatctat ggaacagaca
    21601 tgtcggcaac ctatgatgac cagctgctga ttcgctatgc tcaaaatatt ttggacggta
    21661 aatggctagg ggagtatacg actacaacac tttccaaagg aatctcctac agcttatttt
    21721 tagtacttgc acataaactg catctttctt atgcagtttt gttcggcatg ttcagtattt
    21781 ttgccagtat attggttgca ctcgcgttta aaccgatcgt gaagaacaag tatcttcttt
    21841 taagtttcta tttttatttt ttgttttctc cgattagttt tacacatgaa tattccactc
    21901 gaacgtatcg taatgccctc gtgattccgg ctgttgagat cattatcgct tgtttactag
    21961 ctatttatta ccgtaaatat agttccagca aaaaaatgct gccgtggttt ttagggctag
    22021 ctgtttcttt tcctttcttt tggttcattc gcgaagattc catctggctt cttcctttta
    22081 ctgtagtcgc gttaggcatc agtttcgtcc agatcttgct aggacaagac ttttctttca
    22141 aagaagcaaa gaagttaaaa gaacgaccat ttctcctttc gaaacaagaa tggctgaaac
    22201 tttcattgtt tttactccct ctagtcggtt tctccatcgt ctatcagtgg atcgaatata
    22261 aaaacgagac aacatatagt attgccgcca tcaatgaccg ttcgagtggc gaatttggac
    22321 gtttgatgaa acagctgatc cgaatagatg acgaaacgaa cttaaataaa gaaaacagtg
    22381 agatatgggt ctcgcatgct gcattaaata aagcattaga cgcatctcct acatttcatg
    22441 ctgtttctac tcgtattgac gaattgtata cgactcatgc gtggacccaa ggtggaaaag
    22501 taaaagaatt accaggagat atcatttttt gggcattgcg agatgtggta agcgaatctg
    22561 gttattacca aaacaatgca aaagaaacca atgatttttg gaaaaaagtc aatcaagaat
    22621 tagaagaagc ctatcaaaag ggaactatca aaaagaaaaa agaattctat ctgatgggat
    22681 caggggatgg aaagacgatg aatgatctgc caatcgtatt tgcttttctg aaatcaggat
    22741 atgcctatgc atggcgatac aaagatttcc atcaaggggg gaattatagt ttcggtacgc
    22801 aagaacaagt cgaacaggcc caagaattat tgaatcttcc actaatggat aattggatcg
    22861 atagcagtga tccgagaaca cctgatttcc agttgacaaa aacagcaaaa gtcgcgaatg
    22921 tcatgataaa aatttaccaa gttctggcca ttcccgtgct gattgcttca atagcaggga
    22981 tattacttat gatactagga accgcatttg caaaagctga tcgtgcctat tatagttcct
    23041 ctttgattgt agtcaccgga ttaatactga cacaattggt ttttcttttc ggcgtctcgt
    23101 ggttttgttc ttatgcgcca gaaaaaaagg attatttttt aagtgtctac actggcgcag
    23161 gcgtgccatt aacgcaattc atcgtagtaa caagcatgct agttttcagt aaattgaatc
    23221 tgaaaaaagc tttatcttcc aaataaaaac atactaagat tagaggagaa catcattgac
    23281 gaatgatgtt ctcctctatt ttctattttt agattatagt gaagagtgaa agaaagttcg
    23341 aacaaagcct tgaggacta
//
LOCUS       DACGEU010000041        22728 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.041, whole genome shotgun sequence.
ACCESSION   DACGEU010000041 DACGEU010000000
VERSION     DACGEU010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22728)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22728)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22728
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.041"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(28..1959)
                     /locus_tag="IXR40_001511"
     CDS             complement(28..1959)
                     /locus_tag="IXR40_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIA"
                     /protein_id="HAQ4361366.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAVAEA"
     gene            complement(1977..2891)
                     /gene="pfkB"
                     /locus_tag="IXR40_001512"
     CDS             complement(1977..2891)
                     /gene="pfkB"
                     /locus_tag="IXR40_001512"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HAQ4361367.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(2888..3640)
                     /locus_tag="IXR40_001513"
     CDS             complement(2888..3640)
                     /locus_tag="IXR40_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAQ4361368.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLLNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(3800..4009)
                     /locus_tag="IXR40_001514"
     CDS             complement(3800..4009)
                     /locus_tag="IXR40_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361369.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(4020..5347)
                     /locus_tag="IXR40_001515"
                     /pseudo
     CDS             complement(4020..5347)
                     /locus_tag="IXR40_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(5712..6299)
                     /locus_tag="IXR40_001516"
     CDS             complement(5712..6299)
                     /locus_tag="IXR40_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HAQ4361370.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(6382..7632)
                     /gene="clpX"
                     /locus_tag="IXR40_001517"
     CDS             complement(6382..7632)
                     /gene="clpX"
                     /locus_tag="IXR40_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HAQ4361371.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVELAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(7879..9168)
                     /locus_tag="IXR40_001518"
     CDS             complement(7879..9168)
                     /locus_tag="IXR40_001518"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HAQ4361372.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(9322..10254)
                     /locus_tag="IXR40_001519"
     CDS             complement(9322..10254)
                     /locus_tag="IXR40_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361373.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLKEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(10411..11070)
                     /locus_tag="IXR40_001520"
     CDS             complement(10411..11070)
                     /locus_tag="IXR40_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HAQ4361374.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSLYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAVFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(11073..12098)
                     /gene="sppA"
                     /locus_tag="IXR40_001521"
     CDS             complement(11073..12098)
                     /gene="sppA"
                     /locus_tag="IXR40_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HAQ4361375.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELAPNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAIR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(12111..12401)
                     /locus_tag="IXR40_001522"
     CDS             complement(12111..12401)
                     /locus_tag="IXR40_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361376.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAQAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            12810..14615
                     /gene="glmS"
                     /locus_tag="IXR40_001523"
     CDS             12810..14615
                     /gene="glmS"
                     /locus_tag="IXR40_001523"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HAQ4361377.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDASDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(14687..16042)
                     /locus_tag="IXR40_001524"
     CDS             complement(14687..16042)
                     /locus_tag="IXR40_001524"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HAQ4361378.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(16066..17235)
                     /locus_tag="IXR40_001525"
     CDS             complement(16066..17235)
                     /locus_tag="IXR40_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361379.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(17232..18119)
                     /locus_tag="IXR40_001526"
     CDS             complement(17232..18119)
                     /locus_tag="IXR40_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HAQ4361380.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(18308..22000)
                     /gene="nifJ"
                     /locus_tag="IXR40_001527"
     CDS             complement(18308..22000)
                     /gene="nifJ"
                     /locus_tag="IXR40_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HAQ4361381.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIFPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPTMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLDNANPN
                     LAKALFEKTVHDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARRAARAERRKKMEQATKEKKEK"
     gene            22199..22720
                     /locus_tag="IXR40_001528"
     CDS             22199..22720
                     /locus_tag="IXR40_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HAQ4361382.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLACPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
BASE COUNT         6331 a         4938 c         4040 g         7419 t
ORIGIN      
        1 gaaaacccag cctcttcttt tttatttcta tgcttctgct actgcaggag cttttctcaa
       61 taaaccataa atcacaccag atacgactgc tccgatagca ataaacacca aatacatgac
      121 cgggtgactc agtaagaata caacgaaaat cccgccgtga ggagccagta atttgattcc
      181 gaaagctccg actaatccgc cagttaaagc agaaccaata ataaaacttg gaatggcacg
      241 aatcgggtca gctgctgcaa atggaatcga tccttccgtg acaaacgata gtcccatcac
      301 gatgttcgtc aaaccagcat cttgatctgt tttgctgaat ttattcttaa acaaacgtgt
      361 agcaacgaaa attgccaatg gaggtaccat tcctccagcc ataacagaag ccatcacgac
      421 acttccgcca gttgcaacag tcgtagctaa agttgctgta ccaaacacat aagcggcttt
      481 gttgattgga ccgcctaaat ctgccgccat cattccagct aataatgcac caagtaaagc
      541 agcattcgaa ccactcatac ttgtcaagaa accgttcaat gcatcattga ttgctttcat
      601 agggacattg accagcaaca tcaagaaacc agtaatcagt aagccaaaca ctggataaaa
      661 gaggatcgtt ttaattccat ccaatgattt tggtaagttc ttgaataatt tacgtaaaaa
      721 tacgatgaca taaccagcta agaatccacc aatcagtgca cctaagaatc ctgcaccgcc
      781 tgtattagct aatgcaccag cagcaaatcc aacgatcaaa ccagggcggt caccgatact
      841 tgaagcaata aatcctgcta ataccggcag catgaaacca aatgcagctt gtccgatttg
      901 gttgaaccag ctagcagctt gattgtaatt ccctagattt gataattgat catgtggcac
      961 gccaataaat tggtcgatca tgaaagaaag cgcaatagcg attcctccac caataacgaa
     1021 aggtaacatg tgtgatacgc cgttcatcaa atctttgtaa attctttgtc cgatagtacc
     1081 atccgcattt ccttcttctg aactgctttc ttttccatca ccatggaata ctggtgcagt
     1141 accactaagg gctagattga tcaactcttc tggtttacgg ataccatcac tgacaggacg
     1201 attgatcagt tcttttccgt caaagcgatt catctctact tttttgtctg ctgcaacgat
     1261 tacaccttct gcacgggcga tgtcttcagc agtcaatcgg tttttgattc cttctgaacc
     1321 gttcgtttcg actttgatct ccacacccat ttctttcgct tttttcttca aagcatcttc
     1381 tgccatgtaa gtgtgagcga tccctgttgg acaagctgta acggcaacaa cgaattttct
     1441 ttctggatga gcagaagctt ctgcagcttg tgtttcttgt tctgcttttt cttctgcttc
     1501 tttttgctct tcagctgttt ggaacaagtc ttggacttct tctggtgtat ttgcttcttt
     1561 taattttcct acgaaatctg catcaatcag caatcgagat agtgctgcta atgcttgcaa
     1621 atgtgtgtcg tttgcgcctt ctggagctgc gatcatgaaa aacagataag ttggctgtcc
     1681 gtctaaggct tcataatcta ctcctttttg gctttttgcg aataaaactg ttgcttcttt
     1741 aactgcactg tttttcgcgt gaggcatggc gattccatca ccaagacctg tagaagtttg
     1801 tgcttcgcgg gctagaattc cttctttata tgtttcgata tcggaaatcc ggccggcatc
     1861 aaacattttt tggaccattt catcgattgc gcctttttta tcagtcgctt gcaaatccat
     1921 gatcatcgct tctttgacca ttaaatcctt gatattcatg attatcctcc ttgaaactaa
     1981 tcaatttttg tgatttcaac ttctggcagc aactcatcaa tcaattcgcg agctgccaag
     2041 tcatcagaaa aagctgttgc gcttccgcaa gcaactcccc atttaaaggc ttcgattgga
     2101 tctttcgtac ggctgtaagc cccaataaag ccagcaatca ttgaatcccc tgcacctact
     2161 gaatttttca atgggcgaac taatacattc gttttataag ttccttgttc cgtgaagagc
     2221 aaagcaccgt ctccagccat tgagatcagc acattctgtg ccccttcagc tagtaatttt
     2281 ttcccatacg gaatgatttc ttctacagat tggaaggttg tgttgtaaag ctcagctaat
     2341 tcgtgattgt ttggtttgat caacaacggt ttcttaacaa gtgcattttt taggtcatca
     2401 cctgttgtat caatcacgaa atctgcacct ttttctcgaa tgatatcaat cagttcttga
     2461 taaaatcctt ttcgcaggct agctggcgcg cttcctgaca atacgacgat atctccttgt
     2521 cctactgttc ctaatgcttg cttcaactca tcgatttctt catctgaaat agatgggcct
     2581 aagccattga tctcagtttc agtgtctgat tttagtttga tattgattct tgtatcttct
     2641 tttacggttg tgaacaaaga ctggatttgt tctttttcaa gccacttcga aataaattcg
     2701 ccagtgaacc ctcctaaaaa ccctagtgct gtagattgag aatcgatccg tttcaaaata
     2761 cgggaaacat tgatcccttt tcctccaggt aacttgaagt cttccttcat tcggttcaaa
     2821 tcgcctagtt ttaacccatc tacgcgtacg atataatcaa ttgatggatt aagtgttact
     2881 gtgtaaatca ttgtattgcc tccttaattg ttgtcttttc acggaattca ttaacgaatt
     2941 ctaatggaca acgctcggtt atgatcgtgg ctgcttccaa aggtgcaaca gaggtgaagg
     3001 acaactggtt gaatttggta tgatcaatca atacaaatgt ctcttcggaa tttttcatgg
     3061 ctaaacgttt aacagctgcc tcttctggat ccggagtcgt gaatccttgt tcaagatggg
     3121 caccgttcat tcccataaat gctttattaa aatgaaaatt ttttagttgt tctatcgcat
     3181 tagatcctaa aacagcatta gttgccagct ttatcgttcc acctaaaata atggtagcaa
     3241 gctccaaatc aactaaattt gccgcatgtt gaacggaatt tgtcactact gtgatctgtt
     3301 ttccttgcag aaaaggaatc atttctaacg tagtagagcc agcgtctaaa taaatgacat
     3361 cttcgtcatt aatggtttca gctgccgatt tggcgatttg ctgtttttcg tgaacgtttt
     3421 tgagtgattt ttcactcata ttctgctcaa aattcaataa ttgctctttc ttagctccgc
     3481 catgaactct ttctagaaac ccactattct ccagctcttg taaatcacgt cttatcgttg
     3541 attcagaagc attcaaaagg tttacaagat cttgtgattt cacgattttc tgctgttcaa
     3601 gcaagtctag gattttttgt ctgcgttcct ctgtaagcat tttcacgatc acctcaatac
     3661 aaataatagc atattttttt tctactagca atataaatca gtcaaaaacg ttcataaaaa
     3721 ttataaatca gtcaaaaaaa aaataaaaaa ccagtcagaa agactggttt tttatttttt
     3781 tgtctatcat caagccgttt tatcgttttt tattttcgct tcttgttttt ttcatataaa
     3841 cagaagcagg ttttctttcc ttatgaagaa gataataata aagtcccatc ccgccaaaca
     3901 tgaccaaaaa accgatgact gatcgaatag gaaaattagg aacaaaaaag agacagacgg
     3961 ataataatga tgccggaacc attattcgat aatagagttg tttatccatt ttcttcacct
     4021 catatttttt gtaaagtaat caattgttct aattctcggt aatctaaaaa ttgcacacgc
     4081 agatgctgct cacctttctt gacatcgaat tggatacttc gccgcttttt ctttattcgt
     4141 ttgaaggtaa catcagagag tctatgtttg atttccttta acggtaattc tgacagggat
     4201 tctgaaggaa catagattct taaggataaa agatactctt gatatttttc atctgttacc
     4261 tctacttcta gatattccct aatataataa caataagctt cgattccatt atccaaagca
     4321 acagtcggat cgataacttt atagcacatc atgcgtgatc gattctcgtc aacccaagga
     4381 aaatacgcct gagcatttag tgttccgcga acacgccttt ctttataatc tccttgttgg
     4441 atatcataac tttttgttac aaaaaatgaa gcattctttt taggaacagg ttgcatttgt
     4501 gcattctgat actggacaga ttggatcgta tggtcagtgt aaatgtattc aacgaatggc
     4561 ggtttcaata aaccgacacc attgtcccaa gcaagatgat caaacccaag ctggtcccta
     4621 aaataggatt gaaacatttg attgtttggc ttttgccagt taaaggggtc tcgataaagc
     4681 tggatacata tgacttcgtt ttctaattcc ttcacttttt ctacttgttg gatgtcgaga
     4741 aaaatcggtt tagggatgat ttgatgataa tagcgactat aatacatttc ccaacacgaa
     4801 gtgaaacata aaccttggta aaaaagatcg tatcctggaa attggttgca atcgactact
     4861 acttccccgt tttgttgttt cattttaggt aaatgttcga tttcatcctt tttctcaaac
     4921 aatagccgtt gagagatctg ttttgtattg tgatagataa actcgctata agctcgcata
     4981 taggcgaaca ccccatgagc aatcattttt ttctgaatga agtctcgaat caaaaattgc
     5041 ttttctttga aaacagagat agacaataca ttttttatca ataattgatt atcttccaag
     5101 cgaaaactac attcgttctc gtcatttcct acaactaacc aactttcgtc tcttaccgat
     5161 gctagcatta ttttttcttg aagctttcga agatcatacg gatccgcttg ttgtgtgaaa
     5221 gagcggataa atgttggctg gatcaacaga cgtgtcaaaa tagcccaatc gcttatttcc
     5281 tgtttttttc ttcttcattt aagtctgtga gctggatagt catcaataat ttatcttcgc
     5341 caatcatttt ctcacctctt tcaaatcttt ttataattta attataacca atgataaaga
     5401 aaaactaaaa ctttatgtct tagaaaccaa tttggacgat tacatgatag actaagtaaa
     5461 aagaaacaaa gaggtgttta caatggggtt gaaatttgaa cgtacagata atttagataa
     5521 acttttcgaa tcatttgctg tcgatccgga aaaaacagtt gcaccaaaag aagagatcga
     5581 tcgatttcta aaaccacagc cacaaaatga aaagaaaaaa gacaagaaac aaaagtaagt
     5641 taagctcaaa aaaagactta ccagccaaac ttttatgaaa gagtttgact ggtaagtctt
     5701 ttttattctt tttatgattc aattgcttgt tcgattgctg cccacgcttc ttcttttccc
     5761 tgttttgtaa cggaagaaaa gagaataaac gtgtcattgc gatcaaaatc caacgctttt
     5821 ttgatttcgc tctcatgctt gttccattta ccacgaggga tcttatctgc cttagtggca
     5881 acaacaatta cagggatatc ataatacttc aaaaattgat acatctggat atcttcttga
     5941 gaaggcttat gacgcaaatc tactaaagaa acgaccgcac gtagctggtc tctagtcgtt
     6001 aaatatgtct cgatcatctt tccccatttt gctcgctcag ttttggatac ttttgcatac
     6061 ccatatcccg gaacatcgac aaaatgtaat gcgttctcga tcaaataaaa attcaatgtc
     6121 tgggtctttc ctggcttacc ggaagtacgg gctaaattct ttcgatcaat caatgtgttg
     6181 ataaaagaag atttccctac atttgatcgt cctgccagag ctatttctgg caattgtgta
     6241 tctggatatt gttttggtgc cactgcactt atgataattt cagcttgatg gactttcatg
     6301 gtctctctcc ttaacaaggt gatgaataaa gcaagcggct gtcgcaaaag ccaaaatgac
     6361 ttttacggca gcctcttttc atcaacccgc ttttttctct gaatctttat agattactgt
     6421 tggctcacca gacaattcag ctgcttcttt tgtgataatc actttttcga tgttttcatt
     6481 tgaagggata tcaaacatca catccatcat gatttcttca atgatggaac gaagtcctcg
     6541 agcaccggta ttgcgttcga ttgctttttt cgcaatggct ctcaacgctt caggttcgaa
     6601 ttcaagttcg gtattatcta gagaaagaag tttttgatat tgtttgacta gcgcattttt
     6661 cggctcagtc aagatccgta ccagatcatc tgttgtcaat ttctctaaag ctgccataac
     6721 aggtaatcgt ccgataaact cagggatcaa tccgaatttt agtaaatctt caggaatgat
     6781 atgctgcatg acactttcgt cttcagaaag tttttggttt tgtgtaccaa atccaatcgt
     6841 cttttcgccc atacgattct tcacaatcgt ttcgatgcca tcaaatgcac cacctacgat
     6901 gaacaatatg ttcgtcgtat caatctgaat aaattcttga tgtggatgtt tacgtccgcc
     6961 ctgaggtggc acacttgcaa cagttccttc tagaattttc agcaaggctt gttggacacc
     7021 ttcgccggaa acgtcacgag taatagatac attttcgctt ttacgcgcaa ttttatcgat
     7081 ctcatcaata tagatgatcc ctttttctgc aagttccaca ttgtaatcag cagattgaag
     7141 caatttaagc aaaatgtttt ctacatcttc ccccacataa ccagcttctg tcaaacttgt
     7201 cgcatctgcg attgcaaaag gtacattcaa tgtttttgct aatgtttgtg ctaaaaatgt
     7261 tttaccagac cctgtaggtc cgatcaagca gatattgctt ttttgcagtt caacatcatc
     7321 tgtgttttct tgtgcttgct gattgacacg tttatagtga ttgtatacgg caacagctaa
     7381 cgagcgtttt gcgcgatctt gtccaatcac gtagttattc aatacttcaa gaatttctag
     7441 tggtttaggg acttcagtga attcgcgtac agcttcttca taaaattctt catcaatgat
     7501 ttctttacat aggtcgatac attcattaca gatgtagacc cctggaccag ctacgatctt
     7561 tttcacttct tcttgggttt tcccgcaaaa agaacagcgt acggtctcat tgctacttgg
     7621 attgtcatac atggtcttca ccccttaact tgcaaaaagt atgcaagaaa ctatcaaaga
     7681 ctttacagtc ttttactatc ataacatagt ttagtaaaaa gaaaaagtgt ttaacaaagg
     7741 atcaactgac ctataccttt gcatttttta ctcttaacaa aaaataagga actgtgacaa
     7801 aatcgtgtca cagtccctta tttcgaataa acaattttct agaagtagct tcttcagaaa
     7861 tgatttatta cttgatttct attctttcgc ttctgtcgct gtacctgtga tcaattcgat
     7921 tgcttttttc attgtcacat catgttccag catatcttct gtcaacacgc gtttgatttg
     7981 ttcgattggc atgttgtatg tttctgataa ttcttggatt tctgcattga tttcttcttc
     8041 tgttgcttga agattttcag cagctgcaat tgcttcgatc acaagatttg ttcttgtgcg
     8101 catttctgct tcaccttcga attgtttatg caagtcttct tctgtagaac cagttaattg
     8161 atagtacatt tcaggagaga taccttgacg ttgcatgttg ttcaagaatt cgtccattga
     8221 acgatgtact tcatcatgaa ccatcacgtg tggcaattca acgatttctg cgttttcaac
     8281 agccatacgg atcgctgctt catcttttgc atcgtccgct gctttttctt ttgtttctac
     8341 taattctttg cgatattttt ctttcaattc gtctaatgtt gatacttcgt catcaacatc
     8401 ttttgcgaat tcgtcatcta attcaggcac ttcttttgct tttacttcat ggattgtcac
     8461 tttgaagact gcttcttttc cagcaagatc ttctgcttga taatcttctg ggaaagttac
     8521 atttacatct agactttcac ctgatttatg accaactaat tgatcttcaa aacctggaat
     8581 gaatgagcct gaacctaatt caagtgagta attttcgcct tttccgccat caaacgcttc
     8641 gccatctaca aagccttcga agtcgattac tactgtatcg ccattttcag ctgcagcatc
     8701 ttctttgata actaattcag cttgtgcttc ttgttcacgt ttgatacgtg catccacgtc
     8761 agcatctgtt acttcacggt cttgtttttc aacaactaga tctttatatt gtcctaattt
     8821 tacttctggt ttcactgtta cttcagcagt gattacccag tcttgacctt tttccatgct
     8881 ttcaacatcg atttttggtt gagaaacagg atcgatgcca gcttctttga cagcagcttc
     8941 ataagcttct ggtaatacag cattcaatgc atcttcatat aaagcttctt caccgtacat
     9001 acggttgaat acttgacgag aaactttccc tttacggaat ccaggtacgt tcaagctttt
     9061 tttcacttta ttaaacgcag ttgttaatcc tttttggatt tcgtcttgcg caatcgtaaa
     9121 ttttaaaaca ccatcattcg tgcctttttt ttcaaatgtt gcagtcattt aattccctcc
     9181 gagtttagaa attcatttta tacatcaaaa acgtttcatg cataccttta aatagtacac
     9241 taaccctttc aaattgtaaa catattgaat ggatagaatc cttgtttttc ataacatttt
     9301 tatctttttc actgataaaa tctaatggaa gaagatcatt tgctgcaaaa ttttttctct
     9361 tttttttaaa aaatcttgtt tttcatcttc tgtaccttca tacatcgttt ttcctgtaca
     9421 cgcctctaca gtcagttgaa accagcgctt cgggtcttcg atgtatgtat catagacagg
     9481 ataaacaatt gcagattgca acgtgaattc ttcttttaac acggaactaa gcagcgcatc
     9541 ttcattcccg taacgatctg aaaatacaca taattgctgg taacttgcct gctgctgcgg
     9601 ctttggcaga tcttttggta tgactttgac taacttttct tcaatcgtca aatagaaaac
     9661 aggatggcat tcgttcaatt gcctaagtgt ctccagtaat tttgcccttg ctaaaatatg
     9721 gacctctggc gatacaataa gtttactcgc tgtttggata aactcatgat aaggaagctg
     9781 ttcgatctca tcaatagacg caagctgacg tgcaggttcc aacgaaggaa gttcctccga
     9841 tttattgtgg agtgccttga tcttctgcct ctccatttgt ccggataatt cttctgcaaa
     9901 ttggattttt tcaatgaccc gctgctcgaa agcttcataa aaatctgtac ttgctatcaa
     9961 ttttctagca tataaaaaat cttgtgtact gattaacaag tcaaaataaa attcagcaaa
    10021 ctcctcattt tgaagatact gtttttcatg caagagtgct tgcttcaatg cttctttttt
    10081 ctcgtccaac tcgtaaagac aaaaaacaag caggctatta gcctcaaagc tttctttcaa
    10141 ctcgtaagct cgttgaaata attcttttgc ctgctgatat tgctggtttg ctagtgcttg
    10201 ttgtgccact cgcattaaat tctcatattt ttctggaaaa tcaatcggct tcacgcagtg
    10261 tcctcctctt gctcatattc agctcatgtt caatagtagc aaaacaaaaa aagcatgaca
    10321 attaaaaata actgaagcac cctctaaaag ctagatttta gatctgactt ttagaaggtg
    10381 ctttcaactg ttactgcttt ttattgctca tcagctgttg acttcctggt tgaacgcttt
    10441 gatcagattg atcgtaacaa cacttgtatt agtgaaaaaa tcgcccagat gttgcttttt
    10501 ctgattaaag actgctggaa gataccctaa catcagcaaa ggaaatttta gaatgaaccg
    10561 gcaagcacct tctctaacta aaacggttga ccagctaagt tcttcttcat caaagctgat
    10621 gactcgaata ccaaagatca ttttcccaat cgtttggcca tgattgaatt tcgtcaataa
    10681 aataaaatac gctagataaa taagtaaggc tgtgaatccg tagagactca gataagaatc
    10741 tgaaaaatta agccaaccta gatttttggc aataccaagt gttaaacgcg taatagctcc
    10801 gatacacaaa agatcgacca agaaggcaaa cattcggata aaaaaacctg catagaaata
    10861 cttaggaaaa tcatttgctt ttggcggttc atttcttgtg tccgtatact ttttccattt
    10921 acgttgtttc tttttgattt cttcgggcgt caaaggctct ctttcaaaag agctcagtac
    10981 cttttgggaa aagttggagt caggtcctac agcaggctgc tgttgcttat ctttttcttg
    11041 ttccttattt tcatttgaaa gctctgacat gcttactcac ctccgtaata atacattgct
    11101 tttggtgatt ccgctgtccc tagattctca agaacggata agatctgact agtctcagaa
    11161 ggcttcaatc cctggaattc tgctagttta cttcctaacc atgtactagc aaacccagat
    11221 ggcgtggaag aatattctac tagttccgca tcttcaagct gttgttcctt tcgtatagct
    11281 tttaaagcat cttcaggaaa tcccaattca tcgactaaac ctacttcttt tgcttggaca
    11341 ccatcataaa tccttccatc agcaattttt ttgacttctt cttcagattt attccgtccc
    11401 tcgctgacga ttgctacaaa acgactatat gcgctgtcga tatatgcttg aagcaccgct
    11461 tcttcttctt ttgtctctgg tcgcgttcct gaacccatat ctttcaacgc tccgctttta
    11521 actgttgtat cttccacacc cagtttttct agaagtcctg aataattcaa tcctgacatg
    11581 atcacaccaa ttgagccggt cactgtttct tctgttgcaa agattttatc tgcttgagca
    11641 gaaatatagt agccaccgct agctgccatg tttttcatgc tgacatacat tgggatatca
    11701 tgttctttac gaatcgtatc caatttctta gcgatttccg cactttcgta gacaccgcca
    11761 ccaggagaat ttacttctaa aaagatacct ttgactgttg gatcttcttc aatcgccttc
    11821 agttgttcca taaaattttt atgattgtaa ccttcagaag caaataaacc tgaagaccct
    11881 cccgcagcaa tcgttccatc tactgataat tttacgattt tttgcgtact gtctccctct
    11941 tccaacacat ttggagctag ttcttcatcc ccatataacc aactgttcaa tccctcaatt
    12001 tgatcgtttt cctgaggctt agtcaaacta gctgaaacta acgaaaccac aaataatcct
    12061 gcagcaatca gaactgctgc ccaacgtctt ttattcattc tttctccttt ctaatacaag
    12121 ttttttatga cgatcacagt ttctgactgc tcagaagtgt cgaaccgctc tgctttttct
    12181 tcccgcgcat acccggaaaa cgactctttt gttaattcat cttctaccgt aaactcacga
    12241 gcttgagcaa cttccaaggc atcaggtgcg atttcttgga tgctatccca gccagtatct
    12301 aaaaatattt tcgtatcatc tgatacacca gctgatgctt cgaatttgga caattgtttt
    12361 tttaacattc ccagtgtcat gatctcaatt tttgaatcca tttttactcc tcctctatcc
    12421 gattactttc tattgtaccg aactcctgaa aaagatgata gataaaaacc cattattttt
    12481 tgacataaaa aggacatttg acaaagaatt tgatatatac caatttattt tttattcttt
    12541 ttttgttgac aagaacattc gcaaaaggtt atgattttaa atgtttccag ataaaaaaca
    12601 aaaaggagga tagttatacc ttttaggata gcgccaggtc tgtgtaaaca gatgacgagg
    12661 agagggttta tcgaaagatt cggcggatgg ccctagggac tgcactctac agaaaatcca
    12721 caaaaaatgt ctgcaaagat aaaacaaaag gattttcctg cagctggaag cattcatacg
    12781 aattcattat agaaagtagg atgtttttta tgtgcggaat tgttggaatg attggattaa
    12841 aaaatgtaac accaggattg attgacggtc tagaaaaatt agaataccgt ggttatgatt
    12901 cagctggtat ctttgtctca gatggcacaa ctgattatct ggtcaaagca caaggcagaa
    12961 ttcaaaattt gaaaaacaaa ataaatattg atactacagg aaatataggt attggtcata
    13021 cacgatgggc aactcacggg caaccttctg aagaaaacgc ccatccacat acttcccaaa
    13081 gtggacgctt cgtgctcgtt cacaacggcg taatcgaaaa ctttgaagaa cttaaaattg
    13141 cttatttagc aaatgaccac tttattggtg agaccgatac tgagattatc gctcatctaa
    13201 ttgaaacttt cgcgaaggat actacaacgc aagaggcgtt tttaaaagct ttgcgggtca
    13261 tcaaaggttc ttacgctttc gctttgattg atcggacagc acctgatgtt atttacgtcg
    13321 ctaaaaataa aagtccacta ttaatcggac tcggcgatgg attcaatgtg attgccagcg
    13381 atgcaatggc tatgcttgct catacgaagg aattcgttga gattgaagat gaagagatgg
    13441 ttaccgtcac atcagaaaaa gttattattc aaaattttgc aggtgacatc gtagaacgtt
    13501 cttcattcga agcacaagta gatgcttcag atatcgagaa aggtacctat cctttttata
    13561 tgctgaaaga aatcgacgaa cagcctatta tcatgcgtcg tatcgctcaa aaatacgtaa
    13621 cagaagacaa tcgtgtctct cttgatcaaa agctggtcga tacattgtct gatagcgatc
    13681 gaatctatat cgttgcttgc ggaactagtt accatgcggg gttagcaggt aaacagactt
    13741 tggaaaaatt gacacagatt cctgttgagg ttcatttagc cagtgaattt ggctataaca
    13801 cacctcttct ttcaaaaaaa ccattcttta ttttcttgag tcaaagtggc gaaacagcag
    13861 acagccgcca agtgctggta aaaatcaacc gtctcggcta cccttcactt acgattacaa
    13921 atgttgctgg ttctactctt tcgcgggaag catcctttac actgctattg catgctggac
    13981 ccgaaatcgc agtagcatca acgaaagctt atactgcaca aatagctgta ctaactttat
    14041 tagccaaagc tatcggtgat aaaaaagaat ttgaaacttc tcttgtattc gatatcactc
    14101 atgaattgag tttagttgct aatgcgatgg aatcggtcat cgcccaaaaa gattatttag
    14161 aagagttggc agaagtatat ctcagcgata caagaaatgc cttttacatt ggacgtggtg
    14221 ctgactacaa cgtttctctt gaagctgctt tgaaattgaa agaaatcagt tatatccagg
    14281 cagaaggttt tgccgctggc gaattgaaac atggaacgat tgctttgatc gaagaaggaa
    14341 caccagtgat cggaatcatc agtgaagaag tgactggtgc gcatactcga ggaaacctga
    14401 aagaagtcga aagccgtggc gctaaaacac tagttattgt ctcagaggga ttagaaaagg
    14461 aaagtgacca gctggtgcta ccaactgtcc acccttatct aactactcta accacagtcg
    14521 taccgactca attacttgca tattacgcaa cgctattacg gggattcgac gttgacaaac
    14581 cacgtaattt agcgaaatca gtgacagtag aataataaaa gaacaaggac cagtgtcaga
    14641 catctgacac tggtccttgt tcttttattt tttatgaaaa tatctcttaa tccagtccga
    14701 tttcttcttt gactactgcc gcgattttat cgacatagta attaactttc tcatcagtag
    14761 gcgcttctgc catcactcga agtaatggtt ctgtaccgga aggacgaact aggattcttc
    14821 cttctgatcc catttcagct tctgcctctt caatcacttt tttgattgcc ggaacatcca
    14881 tcgcaccgtt tttatcactt acgcggatat tcactaattt ttgcggatag attgttacct
    14941 ctgctgcaag ctctgataat ttcttacctg tctgtttcat gatattcagt aactgaattc
    15001 ctgaaagcat cccatctcca gttgtgttaa aatctaagaa aatcatgtgc ccagactgct
    15061 cgccgccaaa gttataatcg tttttgcgca tttcttctac aacgtaacga tcaccaactt
    15121 gtgtaacgac atctttcaaa ccgattcctt ccaccgcttt gtggaatcct aagttactca
    15181 tgacagtcgt aacgatcgta tcttttttca atcgattttt ttctgccaag tatttagcac
    15241 agataaacat gattttatca ccgtcgacaa tgtttccaag ttcatccacc gcaataatac
    15301 gatcgccatc gccatcgaaa gctagtccag catctgctcc tttttcaacg accatctcag
    15361 ctaaacgttc tggatgggta gagcctacgc cgtcattgat atttaacccg tctggatttg
    15421 tgcccattgt ataaaaatct gtttcaagat cggcaaacaa acgattaaca cttgttgaag
    15481 ttgctccgtt tgctgcatcg acacaaatgg tcaaaccgga aaggtcaccg ttgatcgttt
    15541 gtacaaggaa ttgagaatat ttcaataagc cttctggaaa ttcttctaca gttcccaatc
    15601 cttcagctga tggacgaggc aattcatcca cttcagcatc taataatgct tcaatttcta
    15661 gctcttggtc atctactagt ttaaaaccat ctgcaccgaa aaatttgatt ccattatctt
    15721 gtgctggatt atgagaagca gaaatcatga cccctgcgct tgctttttgc aaacgtgtca
    15781 gataagcaac acctggtgta gagatcacac ctagctggaa cacttcgata cccaccgata
    15841 aaagtcctga aatcagcgct tcttctaaca tttgacctga gattcttgta tcccgcccta
    15901 ctaacacgcg tgggcgtttt ccttcttctt catgctggct taggacataa cctccgcacc
    15961 gtcccagctt aaatgcaagt tctggcgtaa gttccttgtt ggcttcaccg cgtacgccgt
    16021 ctgttccaaa atatttaccc atagttgtaa aattactcct ttaacttaat tttctgagga
    16081 atttgttctg ctcatttgtg ttgattcgct tgtttctgat gtttcttctg tacttgtggt
    16141 cgagctgctt gtcccagatt ccgaactgga agaaatggtt gttgtcgatg gttccgttcc
    16201 tgaatcagca gatgaaatac ttctactcgt acttgtattt tcttgtgtcc gactgctcgt
    16261 cgaagcagag ctactgcttg acgtttgcaa cacgggtgta atctccacac taactgattc
    16321 gggcttgata cttaacccct cttctactgg tatttcaatt ttacgagttg ttcgatgatt
    16381 gatacctgag acattgatcg gtacagcaat actgtcaccg atcgatgcaa gcaaatcgct
    16441 agagccgctt acttctgctt ccagttttga aaaactgaaa tcatagcttt ctaccccggc
    16501 agctggtgtt ccttgctgta tcccataaag tcgtaccgac ttgcttggct tgatcgaatc
    16561 agctctcact gttacttgca ctggatcaga gacgatactt aatacttccc ctgctgcatt
    16621 cagcgcctgt attgggacct cactattaat cccatcatct gtgaccatcg aagcgtccac
    16681 atcagctact actcgtttga tttctgccaa tgttttgtca cctgtagtga tagagacttt
    16741 tttaggacta acggaagtat catcaagttc atatccagat ggtgtgaacg ttgaaggaat
    16801 caacgtttcc acatcgaaat cttttattac ctttttctca accgttactg taatagtcga
    16861 tggttcgatc tttgctgtga cagcactgct caaattttga atttttagcg gaacttcatg
    16921 tgttccttcg cccagcttag tgatatctgc tgtgacgcgg aacatccgtg tatcttcgtt
    16981 tgcctctgca ttcaactgaa ctcggtttgc actggaaagt ttgacagtca ctgcattttc
    17041 atatccatgg atatagtagc gctttgaatc ataagaaatc ttgatcggca cccccgtaac
    17101 tgtttgatta tacgcttcat ttccagaaag cgtatttgga acggactggc catttgcatt
    17161 gaagtacagc gcaatactga acagcaatgc aataaaactg taaagaatgc ttgtccgttt
    17221 ctcttttgag atcatttgcg atcccctccc ttagtcatac cgtctaggaa agattgaatc
    17281 acgtttttct tgttttttgt tttctcttca gcaattagtt ctctacgcaa gattgccaaa
    17341 tattcttgct gggataagcc agccatcagt tcattatcta acgtgatgct gacgtccccg
    17401 gtttcttcag agacaacgat ggtaatcgcg tcactgactt cgcttatacc gacagctgcc
    17461 cggtgtcgag tcccgaattc tttagggatc aacatacttt ctgatagagg aagataggcg
    17521 cttgctactg cgatctttcc ttcttttaca ataactgcac cgtcatgcag cggtgtatta
    17581 ggaataaaga tattgatcag cagctcccca gtgatatctg catctaaagc aatccctgtc
    17641 tcaatatact catctaatcc agtatgacgt tcgatagtga tcaacgcacc gatttttcgc
    17701 ttggacatat attggatggc tttgtcaaaa gacaagatca tcttctcatc ttcctgctgt
    17761 tcgctttttg attgtttgaa aagcgaactg cgtccaagat gttccagtcc tctccggatt
    17821 tccggctgaa aaatcacgat agcagctatc accccgtacg taatgacttg gttcatcagc
    17881 caagacaagg tgtgcagacc aatgatttcc gctacgattc ggataacaat aaaaatagct
    17941 acacctttca gaagctgaat cgcttttgtg cctcgcagca gttggatcag tttgtataca
    18001 agataccaga caaccagaat atcaagtatg ttcaccaaaa aattcagaga gaacaagtca
    18061 ccggaaaaca tttgctgcca atagtccaaa ttaaaaagtt ccccgatttg aaatgacata
    18121 aaaagcctct cttctctttt gagatttcct ctctagtata tcatatgttt taattttaga
    18181 ggctgatatg ctcgtatttt tcttgagaaa aacgcataat tttcaagaaa attgcaagta
    18241 tgcgttttat ttttctctgc aataaatatt tttaaacttc agagaattat tcattatatt
    18301 ttttctgtta tttttccttt ttttcttttg tagcttgttc cattttttta cgtcgttctg
    18361 ctctggcagc tcttctagca gctcttcttt cttctgcttc aaggtccgtc gttttttctt
    18421 ttctagtctt aacgggtaca tcgatagatt cctctggttc aagtcgtttc ttgatttttt
    18481 ctaattctcc cgtcagtgca gcatagttgt aaaaacgtgt tttagcgtcg tggacagtct
    18541 tttcaaataa agcttttgca agatttggat ttgcgttatc tagcgaggaa aagcgaactt
    18601 gtttcctcat gaaatcaggc atagcagaga aatcaggttt tttgtagtcc aaagtcattg
    18661 ggttcttgtt tttttcgacc attgtagggt tatatcgata taatgaccaa taaccagaag
    18721 aaacagcttc ttttgcttct ttaagcgatt ctttcattcc gccaagcaag ccatgtgtga
    18781 tacaaggcgt ataggcaata atcagagaag gaccaggata cttttctgct tcttcaaatg
    18841 ccttgatcgt ttgcatttga ttggcacctg aagcaatttg cgccacataa acatttccat
    18901 atgtcatcgc catcattcct agatctttct ttgaagcata ctttccacta gccgaaaatt
    18961 tagcgattgc cgaagctggt gttgcttttg aggtttgacc gccagtattg gaatagactt
    19021 cgttatccaa aacaaggata ttcacgtctg ctccgctggc aagtacatga tcgatcccgc
    19081 caaaaccaat gtcgtaagcc catccgtctc caccaatcat ccattggctg ttttttacga
    19141 atagatcctt tctcttgtat atatcctcca gttcagggaa aattgatcgt tcgctttcga
    19201 tcgcagcttg cagttttgct gctctttgct gcgttccttc actctcaaac atgtgtacta
    19261 accagtcttc catcaattct cgtagttctt ctgatacttt tggcaatact tctttgattg
    19321 aacttgccaa agcctcgcga cgagtctgtg ccgctagaag cataccataa ccaaattcag
    19381 cattatcttc caataaagaa tttgaccatg caggcccttg accacattca ttggtcgtat
    19441 aaggagaagc aggagaagca ccgccccaaa tagaagaaca gcctgtcgca ttcgcgatca
    19501 tcattcgatc accgaacatt tgtgtcaata attttacata aggtgtttcg ccacagcctg
    19561 agcaagcgcc cgagaattca agaagcggtt gattgaattg tgtagacaag acagtattct
    19621 ttcctttgac tggatttgct ttttgtctta atgtcattgc aaaagcccaa ttcacagctt
    19681 gttctttctg ttcttcataa ggcttcatca ctaaagcttt ttcttttgcg ggacaagcct
    19741 ctacacacag accacaacct gtacagtctt ccactgaaac ttggatacgg tattttacgc
    19801 cgtctgcgcc tcgcatttct ctcacgataa atccttctgg cgcttcttcc atttcctctt
    19861 catctgctaa aaatggacgg atggcagcat gaggacaaac aaaggcacat tcattacaca
    19921 tcgtacagcg atcactaatc cactcaggta cttctaaagc gacgccccgc ttttccatag
    19981 aagccgttcc taaaggcatt tcgccagttg tcattccatt tgctacaagt gtaccaacag
    20041 agagttgatt tccttcctgt gcattcactg gttcaagtat ttcttgtata taaccagtgt
    20101 tccttttatt gattttttca ggcatctcca acgttctcca atggtctggg atcgcgactt
    20161 gatgaagcag ttcggtcgtc cgatcgattg cttgtatgtt tttttctacg atagccattg
    20221 atttatgtcc atagcttttc agggcttctt cttttagcag cggaagcacc tcatcaaaag
    20281 gaatgatgtc agctaattta aaaaaagccg tttccattgc cgtattgatc cggcgtccca
    20341 aaccgacttc ttgggccaat ctcatggcat tgatcgtata gaatctaatg ttattttcag
    20401 ccaagtaacg ttttaatttt aagggcagat gcgtttctaa ttgttcgtcg ctccaaagag
    20461 tattcaataa aaaaatgcca cctggcttca atcctttgac caagtcatag ctatgcaggt
    20521 aagctggtgt gtgacaggca acaaggtccg catgctcgac aagatacgct gaacgtatcg
    20581 gcgtatctcc aaaacgaaga tgagagacag tcagaccgcc agattttttc gaatcataat
    20641 aaaaatagcc ttgcgcatat ttatcggtgt gatctccaat aatcttgata gctgatttat
    20701 ttgctccaac tgttccgtca gatccaaatc cccaaaactt ggcctggaat gtttgcggtt
    20761 ctgtcaaatc cagactttcc tttggttcca aagattgata agtcacatca tccacgatcc
    20821 ctatggtaaa ccgttttttg cgtatgcttg ggtctttttt caattcatca aaaactgctg
    20881 agatttggtc gggagtcaca tctttagacc ccaatccgta gcgaccacca ataacagccg
    20941 ggcgaagttc agaatcatat aacgcacttt gaacgtctaa taagagaggt tctccacctg
    21001 cccctggttc tttacttcga tcaagaacag caattgtttt tactgtatga ggcaactttt
    21061 gcacgaatgt ttccactgga aaaggacgat aaagatggat attcaaaaaa cctgttttcc
    21121 gtccgtttgc attcaagtaa tcaatcgttt gttcaatcgt ctgtgcaact gatcccatag
    21181 aaacaatgac ttcttccgca tcgtctgctc cgtaataagt caccaagtca taagaagttc
    21241 ctcgtaatcg gttgatctct ttcatatatt tttgaacgat ttcaggtaat ttatcataat
    21301 aggggttgat cgtttcccgt tgttgaaaat ggatgtctgg attctggttc gtaccactaa
    21361 cagtcggatg attgggattc atccctcgtt tacgaaatga agctaatttc tcctgattga
    21421 tcagaggagc taattcttca tattccaaaa cttcgatttt ttgaatctcg tgactcgtac
    21481 ggaatccatc aaagaaattc aaaaaaggga cttctccttc aatagaagca agatgggcaa
    21541 caggtgctaa atccatcact tcttgtacac tgctttcagc taacatagca aatcctgttt
    21601 gtcttgcagc catcacgtct ccgtgatctc cgaaaatatt caacgcattt gtcgtcactg
    21661 cccgactagc aacgtggaaa acacttggca gtagttcccc agcaatcttg tacatattcg
    21721 gtatcatcaa aagcagccct tgtgaagcgg tatatgtagt tgtcagtgca ccagttttca
    21781 atgatccatg gaccacacca gctgctcctg cttcggattg catttctact acttttactg
    21841 gttgaccgaa tacgttttct tttcctgctg ctgaccattg atctactaat tcagccatgg
    21901 tcgaactggg tgttattgga tatattgcag caatctcggt aaatgcataa gaaatatatg
    21961 cggctgccgt attgccatcc attgttttca tttttcgcat gattcatcat ccttgttcat
    22021 attctctctt attatctgtt ccattataac gtaaaacatg ccattttttt cttttattta
    22081 taaaaatatt ttacatgtat ctatttgaat tggtcatcta atttttagac aaacagtcta
    22141 aatcgttgcc tttttttgtc agacatgtat aaactataag cgaaagaggt gttttaacat
    22201 ggatatatca gtgattgatg caacgaaaac aaatacacaa aaaggaatcc tttatggttc
    22261 atcgaatgct cctaaaaaaa tggtcgaatt catcaactta gcttgtccgt attgccgaca
    22321 atggtttgaa gaatcttatg agctattaga agaagcagtc caaagcgggc aattgcagcg
    22381 agtgatcaaa ttgttcgata aagaaaaaga aagcttacag cgagggaacg tgatgcaccg
    22441 gtatctcaca atcagcgatg gccaaaaagc gatcaaagag atcaaacaaa tattcgatac
    22501 tcaagacgag tggaaacatc tttctctcca agaagtagcg gattttgcag tagataaact
    22561 aaagctgaca gaacaaaaag acgaacagct gagccaagct gtcatcaacg aagctgagca
    22621 agcacatatt cgatttgttc caactgtcat cttgggtaaa gaaatctttg atgaatctat
    22681 ttcaatagag gaattaaaag aattgatcca aacaaaataa aaaaataa
//
LOCUS       DACGEU010000042        22661 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.042, whole genome shotgun sequence.
ACCESSION   DACGEU010000042 DACGEU010000000
VERSION     DACGEU010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22661)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22661)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22661
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.042"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            200..475
                     /gene="rpsP"
                     /locus_tag="IXR40_001529"
     CDS             200..475
                     /gene="rpsP"
                     /locus_tag="IXR40_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HAQ4361383.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            487..738
                     /locus_tag="IXR40_001530"
     CDS             487..738
                     /locus_tag="IXR40_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HAQ4361384.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            863..1654
                     /locus_tag="IXR40_001531"
     CDS             863..1654
                     /locus_tag="IXR40_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361385.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            1824..2345
                     /gene="rimM"
                     /locus_tag="IXR40_001532"
     CDS             1824..2345
                     /gene="rimM"
                     /locus_tag="IXR40_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HAQ4361386.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            2335..3096
                     /gene="trmD"
                     /locus_tag="IXR40_001533"
     CDS             2335..3096
                     /gene="trmD"
                     /locus_tag="IXR40_001533"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HAQ4361387.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            3232..3579
                     /gene="rplS"
                     /locus_tag="IXR40_001534"
     CDS             3232..3579
                     /gene="rplS"
                     /locus_tag="IXR40_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HAQ4361388.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            3952..4614
                     /locus_tag="IXR40_001535"
     CDS             3952..4614
                     /locus_tag="IXR40_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010740290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361389.1"
                     /translation="MKQNDGRIIWKNQSELKLILTINEFIEKHGITSSRQYQKKLSEN
                     PNSAPSMWFINKKYGSWENLLISIGRENTGYGKWARMSEQELLEIVEAFIKCEKITSQ
                     RMYEQKSVGKNIPSLSTIKKMLGDIRPLFKEKNDGSRFTDFELLLELKNEIIRLKLQD
                     DLSMTKFRKLVQSPKLPSVDTIMKRTNKNWEELMAEIGFDYRRIKIYKQRNNLSKTKK
                     TK"
     gene            4693..7920
                     /gene="fss3"
                     /locus_tag="IXR40_001536"
     CDS             4693..7920
                     /gene="fss3"
                     /locus_tag="IXR40_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HAQ4361390.1"
                     /translation="MKKPRFKNWRLLATLSLLCQTIGGSLGPTIAFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGVKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSEKAKLVSVLWKEAGTDVDTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     ESKINQAIADYQKKPSFHNSTVKTVLGQSTTVTDTNGLNLSEFDEVVENIANIDYRVN
                     GNQLVITPNANSKESGELTLKKSANTGTPVAYKMAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKETGNVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGAKVTIT
                     EKSVPAPYTIDTTPITATIKSGETISVTSKNTREKGQIILNKMGVETGTDLWNDKYSL
                     AGNTFAIRKDSPTGEIVQEMTTDEKGHAETPKEIANALELGTYYVTETKASNGFVNTF
                     KPVKVELNYVNQTVALVTSNVKGQNQEITGETTLTKEDKDTGNETQGKAEFKGAEYTL
                     FTAKDGQAVKWSEAFKPELVKGTKASDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYTLDETKYPVSIKKVDDNEKNAVITRDVTAKEQVIRFGFDFFKFAGSAAGTAETGF
                     NDLTFKVSPLEGTSEITGAEDEAITAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKADYTKSEYIFTITEKGQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLGTWKDGGKELTDLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     EATKAAQEKDEKAKPVVIAETTATLANKEKTGTWKILHKLTAEQVLDKTIVLFNYVYE
                     NKKPYEAGDDPVAKDASLNNQAQTVNCTVERHVSIQTKAHLEDGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDNTTKEIWKSGKIDYEVNDKEFTKTVLAEKVDT
                     SKYPEGTSFTFKEINYGKDGNINGKHNEDLKEKTQTLTPKKVPTTPSAPEQPEIPTVP
                     SDSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            8034..8348
                     /locus_tag="IXR40_001537"
     CDS             8034..8348
                     /locus_tag="IXR40_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAQ4361391.1"
                     /translation="MELKFVVPDMAETFGKIRYAGEGEVLTEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            8361..8735
                     /locus_tag="IXR40_001538"
     CDS             8361..8735
                     /locus_tag="IXR40_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAQ4361392.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTVSNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIMDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPDQGNSTNQNEGKK"
     gene            8745..9089
                     /locus_tag="IXR40_001539"
     CDS             8745..9089
                     /locus_tag="IXR40_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HAQ4361393.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLTKALTYDEKMFLIMHQGLL
                     EVGNDVEEDFDVLNWLGEEESFFMVIEVNESLCREAETVLEEIGVEMPDAIEVFLKQL
                     VETKQLPIAVND"
     gene            9160..10512
                     /locus_tag="IXR40_001540"
     CDS             9160..10512
                     /locus_tag="IXR40_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HAQ4361394.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQELRQFDI
                     SKLSLSTIEIVRSIKDLIYLLGSLVLSGSTMLLYIHFFQDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTKETISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDIIANRIGIDEVVAESGALRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFVLDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMTRSKAMKEMPNYKTGENYAFLGLPPNFLIFDEYVVYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVDKKFFMKRIKGRGYVDTGGSVISEFYTPLVPKGYDFLREISDIGGLNVNTEG
                     "
     gene            10572..11714
                     /locus_tag="IXR40_001541"
     CDS             10572..11714
                     /locus_tag="IXR40_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HAQ4361395.1"
                     /translation="MTFLDLFAGIGGFCLGMEQAGHQCIGFCEIDDFARQSYKAIHDT
                     SKEVEMHDITSVSDEFIQSLGPVDILCGGFPCQAFSIAGKRQGFSDTRGTLFFEIARF
                     AAILQPKFLFLENVRGLLNHEGGATFETILRTLDGLGYDVEWQVLNSKAYVPQNRERI
                     FLIGHSRDACTEQVFPIIGSSPTSDQNIRNLLNINPSNRGMGGQVYGSDDVAPTLTGD
                     EGIKIALPVDDGISVAGMLLGNFEQGNRVYEITGTAPTLSTKQGGTKIMLRKNETEYQ
                     EVKPGNSVNLAFPNSTSRRGRLGKQSVHTLLTGDQQAVVTDQYQIRKLTPRECWRLQG
                     FPDWAFDRASQVNSDSQLYKQAGNSVTVPVIFDIARRLKEVKTDDL"
     gene            11739..11993
                     /locus_tag="IXR40_001542"
     CDS             11739..11993
                     /locus_tag="IXR40_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361396.1"
                     /translation="MIGKIQSDPELEEELYRLNFDIRKNGVKVPDDPYVIDEETDARM
                     ELNQVISELERIADFAKEPDIRQYLFEIKAELEIEGITAE"
     gene            12249..13433
                     /locus_tag="IXR40_001543"
     CDS             12249..13433
                     /locus_tag="IXR40_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAQ4361397.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATTCGLSRPYLNQIENGGV
                     TASTKTMRKIFDQLESFNPELPLTLLFDYVRIRFPTTDARKIIQEILHLKFDYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPDLTKKCQKEECISLFRTFKSYRSGELLKPDDKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAYHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNQKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNQTTYIQDMVNNTRLSDRHKKILEQQSMAIENL
                     II"
     gene            13448..13567
                     /locus_tag="IXR40_001544"
     CDS             13448..13567
                     /locus_tag="IXR40_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HAQ4361398.1"
                     /translation="MEIVKDILLVFGGSMLGVTVMCLMHASAAADRAMEKKGK"
     gene            14313..16223
                     /gene="ltrA"
                     /locus_tag="IXR40_001545"
     CDS             14313..16223
                     /gene="ltrA"
                     /locus_tag="IXR40_001545"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HAQ4361399.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
     gene            16327..16551
                     /locus_tag="IXR40_001546"
     CDS             16327..16551
                     /locus_tag="IXR40_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361400.1"
                     /translation="MSGTYLSIYQWFLTNAQSLVLLAIVVIGLFLGFKREFSKLIGFL
                     VIALIAVGLVFNASGVKDVLLNLFNRIVGA"
     gene            16564..17064
                     /locus_tag="IXR40_001547"
     CDS             16564..17064
                     /locus_tag="IXR40_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HAQ4361401.1"
                     /translation="MEQIRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELKGTPIGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCNDMSDVAYYLIVEAGDLGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFELM"
     gene            17161..19008
                     /locus_tag="IXR40_001548"
     CDS             17161..19008
                     /locus_tag="IXR40_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HAQ4361402.1"
                     /translation="MVGNKWYKCDLHIHSTASQCFQDKKVTAKEWVEECLNKGLDCVA
                     LTDHNTGENIDEYKKVAIENGLDFFPGVELTCGENGTHLLVLFDKSACTNDISDFLTK
                     MGIKREDWASAAACSMKSVLEVIDFAEHEGLLVIPAHIDEFNGISSAKFGNLGKIFES
                     ENIYAVQTVQKEFFENRSQMIPSSKRDTIYDSVNARYDGRVGKDTLESWYKSVVEAEK
                     NNMTFLSFSDNPHSKGNSKHGLWGIGTRYSYIKMKDEPDLGSLRDALMLGETRVHSDF
                     SNFSINENEVLLEKLSFSGTTLSTKEVVVEFSDNLTSIIGGRGTGKSCITRFLVYVLG
                     KEAELDQFSEIQSDYQNFAQIEHNGSGIFLKDTIVKLNIFYKGTKYQIIRTQDRHSIY
                     EFTQENGLVEKETERLRMISDKVSIYSQKQIYEISKNQTSILELLDGYNSDLISEYKN
                     EIETCVNEIRKLNWDIVSVKKEIQDKAKVELEIEDLKKQVEKLSHKSYKDVYDEYSKE
                     TDIYRELKRDVEALKEIPKNLTDSVDKIDFGNGIKVTDEIDEHRGELIKNLVTNRAKI
                     QTIINEMSDEIDSYRAELNKSDWKVNYNEVSKRYQRGIKNLVKSYLKMN"
     gene            19011..19907
                     /locus_tag="IXR40_001549"
     CDS             19011..19907
                     /locus_tag="IXR40_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAQ4361403.1"
                     /translation="MLQNLDSLYQSLSKTEERLEEIIQQEIKLKDYQVEVDSAMSRMN
                     KSYQNLYSERSSSSREIFSDITGIEATIQPNRDFNNYVKELRACINKEDTFDSEFGSL
                     IDKLTKNSITNQDIYNDILDIRVSGESSIFSDKKLINSIRKLNDAQVLELQTLKPNDL
                     VVIRLELNGKKVSLSNASAGQKTSAILSMILAYGNSPLILDQPEDDLDSQLINNLIVR
                     SIITKKENRQILIVTHNANIPVNGDSEWLISMGDSKEISADQCGSVDEPNIKPRICTV
                     MEGGEDAFTNRAKRYGFKQIVE"
     gene            19957..20346
                     /locus_tag="IXR40_001550"
     CDS             19957..20346
                     /locus_tag="IXR40_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAQ4361404.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEEVFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPSTLVRSVNYVSD"
     gene            20333..>22661
                     /locus_tag="IXR40_001551"
     CDS             20333..>22661
                     /locus_tag="IXR40_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAQ4361405.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELVPYNYSFLSPEQKFQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLKEVAKQRIDIQTDALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKSLKKSFFSGLQEFVYGVNHHLMGDFVSLSNEEI
                     RCYSKLEKLMESKLARRFKVRRVTPSDLTYLIEHIYGEKGIPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPNRCLIEEKPRCLRMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKGSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEISILNLTSKSENQGLLDPYVIMKKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSDQRGLLQVINELRKDGSPIAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDKQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDQEDQSNQKRLRDLEN"
BASE COUNT         7794 a         3717 c         4910 g         6240 t
ORIGIN      
        1 tggagcaaat aaaaacactt actgacaaaa gctacataga agatagatta cttattttta
       61 acaaaaaaga agtctaaaat cttctatttt ctaaaaaaaa tcgaatttaa tcaagctgta
      121 aagaaaaaaa gctttacagg gtaaaaaaaa actgttacac tacatcttgt gaataaaaca
      181 atggaggtgg aaataaataa tggcagttaa aatccgttta aaacgtatgg gttctaaaaa
      241 gagtccgttt taccgtatcg tcgtagctga ttcacgttct cctcgtgatg gacgtttcat
      301 cgaaactgta ggtacttaca atcctttgaa agaccctgca gaagtagttt taaaagaaga
      361 cttagttctt gactggttat caaaaggtgc acaaccttct gacactgtac gtaacatcct
      421 ttcaaaagaa ggcgttatgc aaaaacacca cgaagctaaa ttctcaaaga aataaggtga
      481 ccggatatga aagatttaag cgacttagtc ttaacaatcg ttcgtccgct agtcacttat
      541 cctgatcaag tcaagttaga cgtcgtagag tcgaaagact tttacgagta caatctaaca
      601 gtggctcctg aagatattgg ccgtatcatt ggaaaacaag ggcgtgttgc taaagcaatc
      661 cgcacaatcg tttacggtgt tcggatcaat gcaccgaaaa aagtgcgttt gaatatcatc
      721 gatgataagg aaaagtaaat aaacgtgctg tactcgaatt ttcgagtgca gcttttttgt
      781 tttttttatt aattgaagaa atgattattt ggcaaaacaa gcaagaaagc gtatccttat
      841 aggaggaggg agtgaacagc caatgagaaa gaaaatgtta tttattccat ttgctctatt
      901 gttaagcgct tgtagttcgg ttactcaaga atcagacaat acacatctat caagcagtat
      961 atctgaaact gttaccagtc cagaaaaaag tagtaccaaa acggcttcca ccactgaaca
     1021 aacaatggct acctcaaata atgagaaaaa gactgcttta gaccagttga aagaacaaca
     1081 gccaaatgtt cccatgcctc tagatgtacc agtctcttca ggctatctca atatcgcagc
     1141 gacacataca aagcaaggtt attctatttt atattacaga acagatcgtc ccctcgggtt
     1201 gaatgctgac gaattgaatc aagaaacgcc tattgcaacc tatctatatc aatatgggtt
     1261 tgcttctagt caagaaacaa tccaagtttt gcagccattt gagatcgaca caaatggtca
     1321 gcaagtggac ttaggttctc gaatcacagg gtatcagcaa ggtgcagcag gttcaagttt
     1381 tcttgaatgg caagaaggaa actggcgtat tcgaatccgt gggaataata tagaaggcca
     1441 agatccctta ctattagcta aagaaatcgt agcttatttg gaagaaaaca gtctaccagc
     1501 acctgaacaa tttggtaaaa ttactgttga tatgggtgat acgacgaatc gagccgtaga
     1561 agtaagctgg caagaaccga aaaatgccta tacgatcact catcaagatc ctatgtctgc
     1621 gttgaagatg gcagtttcta tgaagaggtt gtgaaatcag cgcgctgatc tgagcccatc
     1681 atttaactcc aagtcacagg aagtaatcaa aaatagcacg ccgcattttt gcataatttt
     1741 ggcttaatac cttaaaagaa aactagaatt gcctcttcac acatgctaaa ataaaacaga
     1801 caaaaaagaa atggggatat aagttgactg aatacttgaa tgtaggaaaa atcgtaaaca
     1861 cacaaggtat caaaggcgaa gtccgtgtta tctcaacaac ggatttccca gaagaacgtt
     1921 acaaaaaagg aacggtgcta acactattcc aagacggaaa agcacctgtg gaattaacag
     1981 tcaaaagtca tcgcaaacat aaaaattttg acttattgag ttttgaagga catccttcta
     2041 tcaatgatgt ggaaaaatat cgggatggca tattaaaagt gtcaaaagac aactctgtag
     2101 atctagctga aaatgaattc tattaccatg agatcatcgg tctgcatgta ttagaagatg
     2161 gaactgagtt aggtaaagta aaagaaatct tgtcaccagg tgccaatgat gtttgggtcg
     2221 ttcaacgtcc gaaaaaagct gatatattgc ttccatatat cgcttctgtc gtcaaagaag
     2281 tcgatttaga agctggagtg gtccgtgtag aaattccaga aggactgatt gacgatgaag
     2341 attgatgtat tgactttatt tccaagaatg tttgaaggtc ctatggggga atccatcatc
     2401 ggtaaggctg tagataaagg attattagat atcaatatct ctaacttccg cgattattca
     2461 gataacaaac atcagacagt agatgattat ccatacggcg gtggagcagg tatgctgctc
     2521 aaagtccagc ccatctatga taacatccaa gccattgaaa aagctgcacc ggatgtcaaa
     2581 aaaagagtaa ttcttcttga cccagctggt aaacgattcg atcagaaaat ggcagaagaa
     2641 ttttcacaag aagaacactt agtattcatt tgtggtcatt atgagggata tgatgaacgt
     2701 atccgcacat tagtgacaga tgaagtttcc ttaggagatt atgtccttac tgggggagaa
     2761 ttaggtgcga tggtcatgat cgatgcaaca gttcggcttt tgccagatgt gttagggaat
     2821 cagacttcag ctcaaacgga ttcttattca accggtttat tggaacatcc ccaatatact
     2881 cgcccggcag aatataaagg gatgaaagta ccagaagtat tgacaaatgg aaatcataaa
     2941 ttgattgaag aatggcaatt aaaagaatca ctaagaagga cctatcaacg tcggcctgat
     3001 cttttggaaa cacttgaatg gacacctcaa atgacgaaat ttttagaaga aatcaagaaa
     3061 gaagaacaag aaaaaacagc agatgaagcc aagtgacttt ttctaaaatc ttctttacag
     3121 taggttgata atatgttagt attttatggt gagtgcaaaa gcacttaact attacgatat
     3181 tccgctgtga gaaaagctca taagaatatt tggaataagg agaagaaaac catgaatcca
     3241 ttaatcgaag aattaacaaa agaacaatta cgttctgaca tcccagcgtt ccgccctggt
     3301 gacactgtgc gtgttcacgc aaaagttgtt gaaggtactc gtgaacgtat ccagttattt
     3361 gaaggtgttg ttatcaaacg ccgcggtgct ggaatcagcg aaacttatac agtacgtaaa
     3421 gtttctaacg gagtgggcgt tgaacgtaca ttcccattgc atacaccacg tgttgcaaaa
     3481 atcgaagtag ttcgctacgg taaagtacgt cgtgcaaaat tgtactacct acgtgcatta
     3541 cacggaaaag ctgctcgtat caaagaaatc agaagataaa cacggaaaac ttccttggaa
     3601 atctgaaatt tgtgaaaagt ccttgtatat caagggcttt ttcttttttc tctatcacag
     3661 ttttaagcca tttttggctg ttttggacca tttttcaatc atattccctt aaaaattgtc
     3721 ctagattgtc cgacattgac tatcagtgtc gtcaaaatag ggcaaaattt agtagtcagc
     3781 ttgacgacaa atataatacg aaaaatacca aaacatttac cgaatttagc aacttttgaa
     3841 cccaagtttc tcaaagggtc agctattagc aaaaaagaca aaacatgtac ttttctacta
     3901 aaaagttgat gtgataggct tctatctaaa taactattag gagtttttat cgtgaagcaa
     3961 aatgatggac gtatcatttg gaaaaatcaa agtgagttaa aactgatttt aacaattaat
     4021 gaattcatcg aaaaacacgg aattacatct agccgtcaat accagaaaaa gctatcagaa
     4081 aatccaaatt ctgcaccaag tatgtggttc attaacaaaa aatatggatc atgggagaat
     4141 ttattgatta gtataggacg agaaaatact gggtatggaa aatgggctag aatgtcagaa
     4201 caagaattat tggaaatagt agaagccttt attaagtgcg agaagataac ctctcaacga
     4261 atgtacgaac aaaaatcagt agggaagaat attccttcac ttagtaccat taaaaagatg
     4321 ttaggagata tacgtccact ttttaaagaa aaaaatgatg gatctcgatt tactgatttc
     4381 gaactgctgt tagaactaaa aaatgaaata atccgattaa aactacagga tgatttatca
     4441 atgacaaagt ttcgaaaact agttcaatcc ccaaaactac catcagttga tacaattatg
     4501 aaaagaacga acaaaaattg ggaggaattg atggcagaga ttggatttga ttatcgaaga
     4561 atcaaaattt ataagcagag aaacaaccta tccaagacaa agaaaactaa atagtatcac
     4621 tctaaatcag acgttcaaaa ttaaaatttg gacgtctttt ttattaccca aaaacgaaag
     4681 gagatttatt ttatgaaaaa gccaagattt aagaattggc gtttgctcgc aacactgagt
     4741 ctattatgcc aaacaattgg tggatcgctt ggcccaacga ttgcctttgc tgatgaaatt
     4801 actcatccac aaacggtaac tgtggaattg gatttggctc accagtatgc tgtcgaaggt
     4861 acatttagcg atggtcgtcc catgtcagaa gttaccgttc cgcactatgc agtttacaat
     4921 ggtgtgaagc aagatatttt ctgtattgag ccaggggtgc cgatttacaa tgagttcact
     4981 cctggttatg agaaaaatcc attgcctgat atgtcggaga aagcgaaatt agtttccgtt
     5041 ttatggaagg aagctggtac ggatgtggat acacatattg tggcccagaa gatgatttgg
     5101 caagaagtta atggctacac gcttcactca attaaacgtt ctgatggtag tgcagtaaat
     5161 atcgcagcca ttgagtcaaa aatcaatcaa gccattgcgg attatcaaaa gaaaccaagc
     5221 ttccataact ccacagtgaa aaccgtgtta ggtcaatcga ctactgtgac agatacgaac
     5281 ggcttgaatt tatcggagtt tgatgaagtt gtcgagaata tcgcaaatat tgattatcgt
     5341 gtgaacggca atcaactagt gattactcca aatgccaatt caaaagagag tggtgaatta
     5401 accctaaaga agtcagctaa tacaggaaca ccggtagctt ataaaatggc tggtcaacaa
     5461 actttgatgg cgggggcaat tgataagccc aatacctaca caatcaaaat tgatgtggaa
     5521 actgagggtt ctttgaagat taaaaaagtc gataaagaaa caggaaatgt tgtaccggga
     5581 accgttttcc atttagactt tggaaaaaca ttacctgcaa aagacgtgac caccgataaa
     5641 gaaggcattg cgacattgga tgagattcct catggcgcga aagtaaccat tactgaaaaa
     5701 tcagtgccag ctccttatac gattgacact acaccaatca ccgcaaccat taaatctggt
     5761 gagactattt ctgtgacttc aaaaaatact cgcgaaaaag gtcaaatcat tttgaataaa
     5821 atgggggtgg aaacaggaac tgatctttgg aacgacaaat actcattagc cggaaatacg
     5881 tttgccattc gcaaagacag tccaaccggt gaaattgtcc aagaaatgac cacggatgaa
     5941 aaaggtcatg cggaaacacc aaaagagatt gccaatgcgt tggaattggg aacctattat
     6001 gtgaccgaaa ccaaagctag taatggcttt gtgaatacct ttaaaccagt aaaagtcgaa
     6061 ttgaactatg tcaatcaaac cgtggctctt gttaccagta acgtaaaagg gcaaaaccaa
     6121 gaaatcactg gtgaaaccac tttgacaaaa gaagacaaag ataccggtaa tgaaactcaa
     6181 ggtaaagctg agtttaaagg agctgaatat actctcttta ctgcaaaaga tggtcaagcg
     6241 gtcaaatgga gtgaggcttt taaaccagag ttagtgaagg gaacgaaagc ttctgatgaa
     6301 acggtgactt tgactttaga tgaaaagaat caagttgctg ttaaacactt agcgattaat
     6361 gagtattact ggcaagaaac caaagcacct gaaggatata ccttggatga aacaaagtac
     6421 cctgtttcca tcaaaaaggt ggatgataac gaaaaaaatg ccgtgattac ccgagatgtt
     6481 acggcaaaag aacaagtcat tcgctttggc tttgatttct ttaaatttgc tggatcagct
     6541 gctgggactg ccgaaactgg cttcaatgat ctgaccttta aagtatcgcc attggaagga
     6601 accagtgaga ttacaggtgc cgaagatgaa gcaattacag cttataacga gcaactaggt
     6661 tttgatggct atggcaagtt tgaaaatctt ccttatgggg attatttact tgaagaagta
     6721 gaggctccag aaggatttca aaaaattacg ccattagaaa tccgttctac ttttaaagaa
     6781 aataaagcgg attacactaa gagtgaatac atttttacga ttaccgaaaa aggacaaaaa
     6841 caaccaatta aaacggtgac cgttccttac gagaaactga cgaataaagc attttctgtt
     6901 agcttgaatc gtttgatgct ctatgattta cctgaagaag aagatagctt aacttctctt
     6961 gggacttgga aagacggagg caaagaattg acagaccttg attctaccga gctagttgat
     7021 aaattgagct ataacttgca tgaaatcaaa gaagactggt atgtggtagc gcaagccatt
     7081 gatgtggaag cgacaaaagc tgcccaagaa aaagatgaaa aagccaaacc agtggtaatt
     7141 gccgaaacaa ccgcaacgtt ggcgaataaa gagaaaacag gaacttggaa aattttgcat
     7201 aaattaaccg cagaacaagt tttggataaa accatcgtct tattcaacta tgtgtatgaa
     7261 aacaagaaac cctatgaagc aggtgatgat ccagtagcga aagatgctag cttgaacaat
     7321 caagcccaaa ctgtcaattg tacggtggaa cgccatgttt ccatccaaac aaaagcccac
     7381 ctagaagatg gttcgcaaac ctttactcat ggggatgtgg tggatatgtt cgatgatgtg
     7441 tcgattaccc atgatgtact ggatggctca aaagaagctt ttgaaacaat tctgtatgca
     7501 ttacttccgg ataatacgac caaagaaatt tggaaatctg gcaaaattga ttatgaagtg
     7561 aatgacaaag aattcactaa aaccgtactt gcggaaaaag tggacacaag taaatatcca
     7621 gaaggtacaa gttttacctt caaagaaatt aactatggca aagacggaaa catcaatggg
     7681 aaacacaatg aggatctaaa agaaaaaact caaactttaa cacctaaaaa agttccgaca
     7741 acaccaagtg caccagaaca accggaaata ccaactgttc caagtgactc tcaagaatct
     7801 agtcctacag taaagacatt cccacaaaca ggggagaaaa attctaatgt tctgctgttt
     7861 attgggttta ccttgatctt tgcgactgct gggtattatt tctggaatcg ccgaaactaa
     7921 ggtgatgtga tgaaacaact aaataggaaa aaccaacgtg cgcgaccgcc tcctaaaaaa
     7981 agtggtcgcg ctatttttgt atccaaaact aaaaatgaaa agaggaaaag aagatggaat
     8041 tgaaatttgt tgtgccagat atggccgaaa cctttggaaa gataaggtat gccggcgaag
     8101 gcgaagtttt aactgaagga tatgggcgga atactacagt aattggtcgt agttatcatt
     8161 tgtattccag taagcaacga gccgatgata ttgaagtggt ggtagctgcg gaagccggcg
     8221 aaaaggattt tgatcaagat caaccactaa aagccgtgaa tccccatttg gttgccaaag
     8281 gctatgagat tgagaatcgt gggtttaccg actacgtgtt gtatgtcgat gatttagtga
     8341 aagcatagga ggaaaagaag atgagattaa cagaaggtat tgttgtagat tcaggactaa
     8401 cgtttgggaa attacgattt tccgcattac gccgagaagt acggaagcaa aatgaggatg
     8461 gaacggttag taacgaggta aaagaacgga cttataattt gaaatcctct gcgcaaggtc
     8521 gaatgatcca agttagtatc ccagcaaatg tacccttacg cgagtttgcc tatgacgcag
     8581 aggtagagtt ggtcaatcca atcatggata cggtcgccaa ttatgttttc cgagaaggaa
     8641 ctactgtcaa ttggttcatt aaggccgatg atttagtctt gaaacgacaa ccagatcagg
     8701 gaaattctac aaaccaaaat gaaggaaaga aataggtgaa gcgtatggaa attaatgttg
     8761 aacatatttt agattgtctc gatcaatatg gaaaaggtga gctaacggag gaacaactca
     8821 ctaaagcatt aacctatgat gaaaaaatgt ttctgattat gcatcaaggg ttactggaag
     8881 taggtaacga tgtcgaagaa gattttgatg tactgaattg gttaggggaa gaagagtcct
     8941 tctttatggt tatcgaagta aatgaaagtc tatgtcgaga agccgaaacc gtattggaag
     9001 aaattggtgt ggaaatgccg gatgccattg aagttttttt aaagcaacta gtggaaacga
     9061 aacaactccc tatagcagta aatgactagc ataactgctt gaaattggat caatgaaatc
     9121 ctatgaagct tttttcgatt ggaggtggaa accataaaaa tgtacaaagg gcatcgtata
     9181 cgggcaggag atcagcactt ggtttatcac tttgttcttg gctggctact cgctctgttc
     9241 atcggttgga tgagcgtctt ttattttcaa gagcttagac aatttgatat ttctaagcta
     9301 tcactttcta ctatagaaat cgttcgttct ataaaagatt taatctattt gctaggaagt
     9361 ctcgttcttt caggaagcac gatgttgctt tatatacact tttttcagga tcattggcgc
     9421 agtttgtggc atcgacaaaa gctagcccgg atgattctag aaaatcattg gtacgaagta
     9481 aaacaaactc agagtgaagg atttttcaaa gacctcaata gtagtcgaac caaagagaca
     9541 atcagttact tccccaaaat ctattaccgt atgaaggatg gtttactttc tattcgcgtt
     9601 caaatttcac tgggaaaata tcaagatcag cttttaaagc tggaaaagaa gttagaaagt
     9661 ggtctatatt gtgaactagt agaaaaggaa ctcaaagact cctatgtgga gtacacttta
     9721 ctgtatgata taattgccaa tcgaattggg atagacgaag tagtggcaga aagtggggct
     9781 ttgcgattga tgaaaaatca agtatgggct tatgattctt tacctcatat gttaatcgct
     9841 ggcggcacag gtggtgggaa gacttacttt ttactcacta tcatcgaggc tttattaaaa
     9901 tctgatgccg agctttttgt tcttgatccc aaaaatgcgg acttagccga tttaggtacg
     9961 gtaatgcctc atgtctattc ccaaaaggag gaaatttctg cttgtgtgga agatttctat
    10021 gagcgcatga tgactcgtag caaggcaatg aaagaaatgc ccaactacaa aacaggagag
    10081 aattatgcgt ttcttggact tccaccaaac tttttaatct ttgatgaata cgtggtttat
    10141 atggaaatgt taacgacgaa ggaaagtgcg gtgattttga ataagctcaa acaaatcgtg
    10201 atgttaggtc gtcaatctgg tttctttctg attctagctt gtcaaagacc ggatgcgaaa
    10261 tatttaggag acgggattcg cgatcaattt aatttccggg tggctttggg tcgtatgagt
    10321 gaactgggat attccatgat gtttggcgag gttgataaaa aattctttat gaagcgtatc
    10381 aaaggtcgag gctatgtaga tacgggaggg agtgtgatta gtgagtttta tacgccactt
    10441 gtaccaaaag gatatgattt cttaagggaa attagcgaca ttggtggatt aaacgttaat
    10501 acggaaggat aaaataatag tatgtagcct aggagtgtca agaatcctgg gcttttttta
    10561 cgaggtgatt tatgacattt ttagatttat tcgctgggat tggtggcttt tgcttaggta
    10621 tggaacaagc gggtcaccag tgtatcggct tttgtgaaat tgatgatttt gctcgccaga
    10681 gttataaggc aatccatgat acaagtaagg aggtggaaat gcatgacatc acaagtgtat
    10741 cagacgagtt tattcaatct ctcggaccag tggatatcct ttgcggtgga tttccgtgcc
    10801 aagctttttc aattgcggga aagcggcaag gattttccga tactcgaggt actttattct
    10861 ttgaaatcgc tcggttcgcc gctattctcc aacctaagtt tttattcctt gagaacgtcc
    10921 ggggattact caatcacgaa ggaggggcta cgttcgagac gatcctccga acgctggatg
    10981 gattggggta tgatgtggaa tggcaagtgc ttaactcaaa ggcctacgtt ccccaaaacc
    11041 gtgagcggat cttccttatc ggacattctc gagacgcatg taccgaacaa gtatttccta
    11101 tcattggatc gtctccaaca tctgatcaaa acatcagaaa cttattaaat atcaaccctt
    11161 ccaatcgagg aatgggggga caagtctatg ggtcagatga cgtagcgcct accttgaccg
    11221 gtgatgaagg aatcaaaatc gcattgccgg tagatgatgg aatttctgta gcgggtatgt
    11281 tactgggaaa ttttgaacaa ggcaatcggg tttatgagat aactggaaca gcgcctactt
    11341 tgtcaacgaa acaaggcgga acgaagatca tgcttcggaa aaacgaaaca gaatatcaag
    11401 aggtgaagcc agggaacagt gtgaacctgg cttttcctaa ttccacaagt cgtcgaggcc
    11461 gtctgggaaa acaaagtgtg cataccttat taacaggaga ccaacaagca gtcgtcacgg
    11521 atcagtatca aattcgaaag ttaacaccta gggagtgctg gcggcttcag ggctttccgg
    11581 actgggcttt tgatcgagct tctcaagtca attcagatag tcagttgtat aagcaggctg
    11641 gaaattctgt aacagttccg gtcatttttg atattgctag aagattaaag gaggtaaaaa
    11701 cagatgattt atgatgagtt gattggggaa tctactgggt gattggcaag attcagtcag
    11761 atccggaatt ggaagaagaa ctgtaccggc tcaattttga tattcgcaaa aacggggtga
    11821 aagtccctga tgatccgtat gtaattgatg aggaaacgga tgctcgaatg gagctgaatc
    11881 aagtcatcag tgaattggaa cgaattgcgg actttgctaa agaacctgat atccgccaat
    11941 acttgtttga gataaaagca gagttggaaa ttgagggtat taccgcggag taacggccaa
    12001 ataaaccact gataggcact gaccgcgggg gatttgcgaa gcagaaatcc tccgtggtgc
    12061 tgtgcctgtt tatggacggc gttagccggc catgatgtct caccccccgt atctaacagg
    12121 ggggtacaaa aacacaaaaa ataagcaagc aacgataagg aatggctgtc ctatcaagga
    12181 taataagcaa tttgtgtaga tgttaactga tttgaaaaag ttaacacctt aaatttggag
    12241 gtgagaactt ggcacaaagg aatttagatt atcggctatt aaaagaccgg cgtaatgaat
    12301 atggcgtttc acaaaataaa ttagctacga cttgtggact tagtcgcccg tacttaaatc
    12361 agatagaaaa tggtggcgta accgcatcga caaaaaccat gaggaaaatt tttgaccaac
    12421 tggaaagttt caatcccgag ttacctttaa cgttactgtt tgactatgta aggattcgct
    12481 ttcccacaac ggatgcgagg aaaatcattc aagagattct ccatttgaaa tttgattata
    12541 tgctccacga agattacgcc ttttactcct atcaagaaca atatgttatg ggagatattg
    12601 tggtgatgtt gtcacatgaa gaagataaag gcgtcctttt agaattaaag ggtcgtggtt
    12661 gtcggcagtt tgaaactttt ttactcgccc aaaagcgtag ctggtatgac tttttcgaag
    12721 attgtctaaa agccggtggc gtgatgaaac gcttagacct ggcaatcaat gatcgagttg
    12781 gcctgttaga tattcctgat ttaacgaaaa aatgtcagaa ggaagaatgt atctccttgt
    12841 ttcgtacctt caaaagctat cgttccgggg aactgttgaa acctgatgat aaagatggta
    12901 tgggcaatac tttgtatatt ggcagtctta agagtgaggt ctatttctgt ttgtacgaaa
    12961 aagactatga gcaatatatc aagttaggga ttcctttaga ccagaccgaa acgaaaaatc
    13021 gttttgaaat ccgactgaaa aatgatcgag cttatcatgc aattcaagat ttgttaaaag
    13081 gtcgcagtat tgaaagtacc acattttcca ttattaaccg gtacttgcga tttgcggata
    13141 aggtggaagg caaaaggcga actaactggc ccttgaatga acaatggggg cgcttcattg
    13201 gacggaatca gaaggaaatt caattaactt ctgaaccgaa gccttatacc attgaacgaa
    13261 cgttgaactg gcttggacga caagtcgccc ctacgtggaa gatggccaag gagttggatc
    13321 ggttgaatca gacaacgtac attcaggata tggtaaataa tactcgacta tcagaccggc
    13381 acaaaaagat tttggagcaa caaagtatgg caattgaaaa tttgattata tgaaaagagg
    13441 aatcgtgatg gaaattgtga aagatatttt attggtgttt ggtggcagta tgcttggtgt
    13501 tactgtgatg tgcttgatgc atgcaagtgc agcggcggac cgagcaatgg aaaagaaagg
    13561 aaagtgatga aatgaatttc ggtcaaaatt tgtgtgcgac tcgttcctta gtgaaaagct
    13621 aaggcactaa taaaagaacg aaaaagtttg gttattagga gaactgataa tctgacaggt
    13681 ggaatgatga agtaacgctc tgaaacgcct gccctgagcc tccgacaagc attgtatgag
    13741 gaaactcaga atgtttgaag ctcggtaaag acggctgaaa gataccgtaa tagttgatga
    13801 acatatatct tctatcgaaa actatccaga ggtgggtagc gtatccaaca ggtcgggggt
    13861 ctataaaata tctatggtta gaatgttcta taaggaactg acgaaacagc gaatgtacgg
    13921 gtctaaattt gaactttgta gaaatgcaaa ggtacgagaa atcgtagctg gtgtggcaaa
    13981 gtaagaatat aggttatgaa atgccatata acgttacagg cggtatcaag ccagcaggct
    14041 tatagctagt gacctaagga tatatatgta tagataagat tatcggaacg aggaaaggta
    14101 ttgggttctc atcaagagaa taaactgacg aagaacaata agcagttgaa ctaatgctga
    14161 aaagcagagg gcgaacctaa gaaattcttg taatgagaat ggaggaatgc cctcaagtcg
    14221 tgtatatatt agaaaagtat tatgttgttt caataaggat tacgagtaag ataaaaaagc
    14281 tcactcaatt tcaagtaaag gagtgaagcc ttatgcctaa aaataaaaat gaaacattgt
    14341 gtgtagaaga tttaagacac gctgaatatt acgaaatgca aaacaccttt gatgatttat
    14401 atgccaaaag taagaatgga gatattttca ctcatcttat ggatattatc ctatcgagag
    14461 aaaatatatt actggcatat cgaaatatca aagcaaatgc aggcagtaaa acagcaggaa
    14521 cagacggtac aataattaaa gatattggca aattgccagc agaaacagtt gtcaaaaaag
    14581 taagatacat tgttgcaggc agtccacatg ggtatcgacc taagccagtg aggcgaaaag
    14641 aaataccaaa accaaatggt aaaaccagac ctctaggtat tccttgtatg tgggacaggc
    14701 ttatacaaca atgtataaaa caagtattag aaccaatctg cgaagctaaa tttagtgaaa
    14761 acagctatgg ttttagacct aataggtcag ttgaaaatgc aataaaagca acctataacc
    14821 gcctacaaat cagccagcta cattatgtga ttgaatttga tattaagggt ttctttgaca
    14881 acgtgaacca ttccaagctg ataaaacaga tatgggctat gggaatacgg gacaagcact
    14941 tgatattcat tttaaaaagg atattaaaag ctccaatcaa aatgactaac ggtacaataa
    15001 catatccaga gaaaggaact ccgcaagggg gaataatatc cccactacta gcaaacattg
    15061 ttcttaatga gttagaccat tgggtagaaa gccaatggca ggaaaatcct gttacaaaaa
    15121 actatgtggt tcatatcaat aaaagcggta gcccatgtaa aagcaacgct tacaaagaaa
    15181 tgaagaaaac aaagttaaag gaaatgtata tggttcgtta tgcagatgat tttagagttt
    15241 tctgccgcta caaggaaagt gctgaaaaag ccaaaatagc aatcactcaa tggattgaac
    15301 aacgattaaa attggaagta tcacaagaaa aaacaagaat tgtaaatgtt agaaaaagat
    15361 actccgactt tcttggtttc aagattaaaa tgataccgag aagaaagaag ttagttgtta
    15421 aatcacatat aagtgataaa caattcaaaa accaaaaaga caagctggta tcacaggcaa
    15481 aaaaaattgc ttctccctca aaagggaaaa cggaattaga agaaacaaga ctttataatt
    15541 caatggtatt aggtatgcaa aattattatc agattgcaac gaatgtaaat ctggattgta
    15601 tgaaactgaa tagagctgta atggctatct tcactaacag attaggtaca aacaaaaggg
    15661 gcagattgag aaaaacaggc agacaactta cgacaaagga ggcaacaaga tatggtaaat
    15721 ctaaaatgct tcggtatgtt gctggcgagg gcgaacctat tttccctgtt ggatatatcc
    15781 aacacagaaa accaatggca aaggtgtatt tagcgaattg ctacactcta gagggaagaa
    15841 aatttatcca caccaatcta agtgttgata aattactgat gtaccagtta atgaaattat
    15901 ctttggaaaa tcgcacaata gaatacgcag acaatcgaat ttcgctattt tctgctcaac
    15961 atggaaaatg tgctataact ctggaagaat ttcaacaagc taatgaaata cattgtcatc
    16021 atattgtacc aactggagct ggtggaaatg acgattataa aaatcttatt ttggtaaaag
    16081 aggcggtaca ccgtctaata cacgctaaaa cagaagaaac aatacaaaaa tatatagctc
    16141 tattgaagct aaataaagtc cagctcataa gactaaataa atatagagta ttagctggca
    16201 atcaagaatt aaacttgata taggtctact acataaatac ttttcaatat aaacacgatg
    16261 gaacgcggag tgcggtgaaa gtcgcacgct ccgtgtgaat ggggggaaaa gtttgagata
    16321 tttataatat caggaactta cctatccata tatcaatggt ttttaaccaa tgctcaatct
    16381 ttagtcttac tagcgattgt ggtcattggt ttgtttttag gatttaaacg cgagttttcc
    16441 aaactgattg gcttcttggt gattgctttg attgcggtag gtctggtctt taatgcttct
    16501 ggtgtgaagg atgtcttact caatttgttt aaccgaattg tcggtgcctg agggggaatc
    16561 acaatggaac agatacgtgt ttatattgcg aaccttggaa aatacaatga aggtgagttg
    16621 gtgggggcat ggtttacccc acccgtcgat tttgatgaag tgaaagaacg gattggatta
    16681 aatgacgaat atgaagagta cgcaattcat gattatgaac tgccttttga gattgatgag
    16741 tatacaccaa ttgaggaaat taatcggttg tgtggtttag cggaagagct taaaggaacg
    16801 ccaattggtg aggtcgcttc agagattcaa catgccttct tcaattcttt cgaggaaatg
    16861 gtagagcatg tggatgatat catctattat cccgattgta atgacatgag tgatgtagcg
    16921 tattacttga ttgtagaagc tggtgattta ggcgaagtac cagaacactt gaagacgtat
    16981 attgattttg atgcgtgtgg tcgagacttg gagattggcg ggaattattt ggttacgagt
    17041 cgaggggttt ttgaactaat gtaaatcatt tgttagaatt gaccagaaat ttctatcgta
    17101 cttttacttt tctatttgat atactgaaat agaaaatatt tgttgatagg ggtgttacta
    17161 atggttggca ataagtggta caaatgtgat cttcatattc attcaactgc gagtcagtgc
    17221 tttcaggata aaaaggttac tgctaaggaa tgggtagaag aatgtttaaa caaaggactc
    17281 gattgtgttg cattaactga tcacaataca ggggaaaata ttgatgaata taagaaagtg
    17341 gctatcgaaa atggcttaga tttttttcct ggagtggaat taacgtgtgg agaaaatgga
    17401 actcatttac tagtcctatt tgataaaagt gcatgtacaa atgatatctc tgatttctta
    17461 accaagatgg gtataaaaag agaggattgg gccagcgctg cagcttgctc aatgaaatca
    17521 gttttagaag ttattgattt tgctgagcac gagggcttgc tcgttattcc tgcacatata
    17581 gatgagttta atggaatttc ttcagcaaaa tttggaaatc taggaaagat atttgaatca
    17641 gaaaatatat atgcagtaca gacggttcaa aaagaatttt ttgaaaatcg ctcacaaatg
    17701 attccctcat ctaagcgtga cactatctat gatagtgtga atgccagata tgatggtaga
    17761 gttggaaaag atactttgga atcttggtat aaatcagttg ttgaggcaga aaaaaataat
    17821 atgacatttc ttagcttttc tgataaccca cactcgaaag gaaattcaaa acatggactt
    17881 tggggaatag gcacaagata ttcctatata aaaatgaagg acgaacctga cttgggatca
    17941 cttcgcgatg ctttaatgct aggcgaaact cgagttcatt ctgatttttc taatttctcc
    18001 attaatgaaa atgaagtttt attggaaaaa ttaagctttt ctgggaccac tcttagcaca
    18061 aaagaagttg tagtcgaatt cagcgataat ttaacttcaa ttattggagg aagaggaaca
    18121 ggcaaatctt gtattacaag attcttggtc tatgtccttg gaaaggaagc agaacttgat
    18181 caattttctg aaatacaaag tgattatcag aactttgcac aaattgaaca taatggctct
    18241 ggaatatttt tgaaggatac aattgtgaaa ctgaatattt tctataaggg gacaaaatat
    18301 caaataataa gaacacagga tagacattct atttatgaat ttacacaaga gaatggtctg
    18361 gttgaaaaag aaacagaacg gttgagaatg atttccgata aggtgagtat atactctcaa
    18421 aaacaaattt atgaaatttc aaaaaatcaa actagtatac tagaattact agatggatat
    18481 aactctgatt tgatttcaga gtataaaaat gagattgaaa catgtgtaaa cgaaataaga
    18541 aaattaaatt gggatattgt ttctgtgaaa aaagaaatac aagataaggc gaaggtagag
    18601 cttgaaattg aagatttaaa aaaacaagta gaaaagctat ctcataagag ttataaagat
    18661 gtttatgatg agtattcaaa agagacagat atttataggg aactgaaacg tgatgtggag
    18721 gcacttaagg aaattcccaa aaatctaact gatagtgttg acaaaattga ctttggcaat
    18781 ggtataaaag ttacagacga aattgatgaa caccgcggag aattgattaa gaatttagtg
    18841 accaatcggg ctaagattca aacaataatt aatgaaatgt cagatgaaat tgatagttat
    18901 agagcagagc tgaataaatc agattggaaa gttaactata atgaggtttc aaagaggtat
    18961 caaagaggta tcaaaaactt agtgaagagt tatctcaaga tgaattaaaa atgttacaaa
    19021 accttgattc tttatatcaa tctttatcaa aaactgaaga gcgattggaa gaaattattc
    19081 aacaagaaat aaagcttaaa gattaccaag ttgaggttga ctcagcaatg tcaagaatga
    19141 ataaatcata tcaaaatctc tattctgaga gaagtagttc ctcgcgcgaa attttttctg
    19201 atattacagg aatagaggct actattcaac caaataggga tttcaataat tatgttaaag
    19261 agctcagagc ttgtattaat aaggaggaca cttttgacag tgagtttgga tctcttattg
    19321 ataagctgac aaaaaattcc attactaatc aagatatata taatgacata cttgatataa
    19381 gagttagtgg ggaaagtagt attttttcag ataaaaaatt aatcaattct ataagaaaat
    19441 tgaatgatgc acaagttctt gaattacaaa cccttaagcc aaatgattta gtagttatcc
    19501 gacttgaact aaatggaaaa aaagttagtt tatcgaatgc tagtgctggt caaaagacat
    19561 ctgcaattct ttctatgatt ttggcgtatg gaaattcacc actcatattg gatcagcctg
    19621 aagatgattt ggatagtcaa ttaattaata acttaatcgt aagaagtatc attacaaaaa
    19681 aggaaaacag acaaatttta attgtaactc ataatgcaaa tatcccagtt aatggtgatt
    19741 cagaatggtt gattagcatg ggagattcaa aagaaatatc ggctgatcag tgcgggtcgg
    19801 tagatgaacc caatatcaag ccaagaatat gtactgtgat ggaaggtggc gaggatgctt
    19861 ttacaaatag agcgaaacgc tatggtttta aacaaattgt agaataacac tagagggtga
    19921 gacatattat tatgtccgcc ctttttagga ggaaaaatga aaaaaataaa aagctatacc
    19981 agtatctggg cagttgaaaa agtcatttac gcaatcaatg attttcagtt gccttttcct
    20041 gtgactttta accaaatggc ttggttcgtt ttatctttac tgtttgtcat cgtatttgcc
    20101 catgtgcctc cactatctat gatagaggag gtctttttaa aatacttagg cataccggtg
    20161 gctgtcactt ggtttatgtc gcaaaagacg tttgatggca agaaaccact gggattttta
    20221 cgatccttta tcagctatca cttgcgattt aaggtgactt ttgcaggaaa gaaagtcaaa
    20281 gaacagaaga aacgatggga tgaacccagt actcttgtaa ggagtgtgaa ctatgtatcc
    20341 gattaagtat attgaaaata atctcgtctt taaccaagaa ggcgagtgtt ttgcctacta
    20401 tgaattagtg ccttacaatt actccttttt gtcacccgaa cagaaatttc aagtgcatga
    20461 taactttcgc caactaattg cgcaaaatcg tgaaggcaag atccatgcgt tacaaattgc
    20521 cacagaaagt agtattcgcg ccacacaaga acgatcaaaa aaagaaatta ccggtagact
    20581 caaagaagta gcgaaacaac gaattgatat acagacagat gcattagtat ccatgattgg
    20641 cgatagtcag attgattatc gcttttttat tggctttaaa ctaattgcga cagatgaaga
    20701 agtcaatcta aagagtctca agaaatcttt cttttctggg cttcaagaat ttgtctatgg
    20761 agtgaatcat catttgatgg gcgattttgt ttccttatcc aatgaagaaa ttcgctgcta
    20821 ttctaagctt gaaaaattaa tggaaagcaa attggctcga agatttaaag tcaggcgagt
    20881 cacaccgagt gacctgacgt atttgattga acatatttat ggcgaaaaag ggataccgtt
    20941 tgaagaatac gaatttcagc taccaaagaa aaagctaaaa tcagaaacac tggtgaaacg
    21001 ttatgactta ttacgtccaa atcgttgttt aattgaagaa aaaccaaggt gcttacggat
    21061 ggaacatgag aatcatgagt cgtacgtagc gtatttaaca attaatacaa ttgtggggga
    21121 gatggaattt ccttcctcag aacttttcta ttaccagcaa caacaattta cattcccaat
    21181 cgacacaagt atgaatgtag agattgtgac gaataaaaag gctttagcta ccgttcgtaa
    21241 taagaaaaaa gaactgaaag atttagacaa tcatgcttac caatctgaca atgaaacgaa
    21301 ttccaatgtc ttagatgctt tggattccgt ggatgaattg gaaaccacct tggatcagtc
    21361 aaaagaatct atgtacaaac tgagttatgt ggttcgagtg agtgccgaat cagtggatga
    21421 actaaagcga cgctgtgatg aagtgctcga tttttatgat gataccaatg taaaactagt
    21481 ccggcccttt ggcgatatga tggggctaca tgaagaattc ttaccctcaa gtaaacgata
    21541 tatgaacgac tatattcagt atgttacgtc tgattttttg gcggggcttg gttttggggc
    21601 tactcagatg ctaggagaat tagaagggat ttactttggc tacaatgtgg atacaggtcg
    21661 taatgtttac ctgaaaccgg cattggcttc acaaggagtc aagggttcag taaccaatgc
    21721 gctggccgcc gctttcctgg gttctcttgg tggaggtaaa tcctttagta acaatctctt
    21781 agtctactat gctgttttgt tcggtggtca agctgtgatt gtcgatccaa aaggggagcg
    21841 aggagggtgg aaagaaacct tgccagaaat tgcggatgaa atcagtatcc tcaacttgac
    21901 gagtaagtca gaaaatcaag gtctgcttga tccttatgtg attatgaaga aaaagaaaga
    21961 ctcggaaagt ttagcaattg atattctgac ttttttaaca ggaatttcaa gtcgagacgg
    22021 ggagaagttt cctgtgttac gtaaagccat tcgaacggtg actcaaagtg atcaacgggg
    22081 gttattacaa gttattaacg aattgcgaaa agacgggtca ccaatcgcgg aaaatatcgc
    22141 cgatcatatc gagtccttta ccgattatga ttttgctcat ttgcttttct cagacggctc
    22201 gattacccaa tcgattagtt tagataaaca gctaaatatc attcaagtgg cggatttggt
    22261 tttaccggat gcagaaacga cttttgaaga atataccacc atggaattgc ttagtgtttc
    22321 gatgctaatc gtcatttcca cttttgcctt ggactttatc catagtaacc gagaaatctt
    22381 caaaattgtc gatttggatg aggcttggag ttttcttcaa gtggctcaag gaaaaacgtt
    22441 atcgaataag cttgttcgtg ctggtcgggc catgaatgct ggggtctatt tcgtcactca
    22501 aaatagcgac gatttattag atgaacgttt aaaaaataat atcgggttga agtttgcttt
    22561 tcgcagtacc gatattcatg aaatcaagaa aaccttggaa ttctttggtt tggatcagga
    22621 ggatcaaagc aatcaaaaac gcctgcgaga tttggaaaac g
//
LOCUS       DACGEU010000043        22621 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.043, whole genome shotgun sequence.
ACCESSION   DACGEU010000043 DACGEU010000000
VERSION     DACGEU010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22621)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22621)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22621
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.043"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..323)
                     /locus_tag="IXR40_001552"
     CDS             complement(<1..323)
                     /locus_tag="IXR40_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361406.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIVCGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQRRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDT"
     gene            complement(347..1318)
                     /locus_tag="IXR40_001553"
     CDS             complement(347..1318)
                     /locus_tag="IXR40_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HAQ4361407.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            2024..3403
                     /gene="brnQ"
                     /locus_tag="IXR40_001554"
     CDS             2024..3403
                     /gene="brnQ"
                     /locus_tag="IXR40_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HAQ4361408.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGANWV
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYNSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFHPMGNLNQSAADTYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKTPFVYQVTMLFAAVPAVLDM
                     LANSPALVSQQRVVASMLEFYHHHVPFAALGLGWMVPTLLGYAGSLLFYYAYRLSGYK
                     QEANELPEE"
     gene            complement(3559..4005)
                     /locus_tag="IXR40_001555"
     CDS             complement(3559..4005)
                     /locus_tag="IXR40_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HAQ4361409.1"
                     /translation="MSLLSRLNDDMKTAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
     gene            complement(4032..4208)
                     /locus_tag="IXR40_001556"
     CDS             complement(4032..4208)
                     /locus_tag="IXR40_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HAQ4361410.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            complement(4370..4798)
                     /locus_tag="IXR40_001557"
     CDS             complement(4370..4798)
                     /locus_tag="IXR40_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HAQ4361411.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            4890..5750
                     /locus_tag="IXR40_001558"
     CDS             4890..5750
                     /locus_tag="IXR40_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HAQ4361412.1"
                     /translation="MSSDSTEIVTFFVISDSAGETATKLAQATMAQYPSVEFNLFRRT
                     FVTDEKTLMQALQDALEEKALVLHTLINQELIEMTRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEETD"
     gene            complement(5834..6127)
                     /locus_tag="IXR40_001559"
     CDS             complement(5834..6127)
                     /locus_tag="IXR40_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HAQ4361413.1"
                     /translation="MPDTQKTKVEKVSQLFKMLSDPTRLKILLYLKDGEQNVTAIIQA
                     VEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHVLDILNQTLKHVEHQ"
     gene            complement(6200..7927)
                     /locus_tag="IXR40_001560"
     CDS             complement(6200..7927)
                     /locus_tag="IXR40_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HAQ4361414.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDEEAEHSGLITIIGEEVDAAYLEEIKAV
                     TIDHELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAIRLGEKEGADLLIATDPDADRLGAAVRLPNGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYYAEKTISVTMSGQEGSAKISALMEKFREEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGNSSEDAAEKVAAYE
                     TIIQKMTEE"
     gene            complement(8140..9066)
                     /gene="trxB"
                     /locus_tag="IXR40_001561"
     CDS             complement(8140..9066)
                     /gene="trxB"
                     /locus_tag="IXR40_001561"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HAQ4361415.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYEGVSRFGTENAYGIVQDIKDHGSHKEVICEDKTYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNIPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            complement(9211..10644)
                     /gene="ascB"
                     /locus_tag="IXR40_001562"
     CDS             complement(9211..10644)
                     /gene="ascB"
                     /locus_tag="IXR40_001562"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HAQ4361416.1"
                     /translation="MGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGEDRFPV
                     ITGKKKMFEFDENHFYPAKIAIDMYHHYKEDIALFAEMGFKTYRMSIAWSRIFPMGDE
                     KEPNESGLKFYEDVFKECQKYGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENLC
                     RVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEEGENEEQIKYQAAHHELVASAI
                     ATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPAY
                     ALKEMERNGIQIKMEPGDAALLKEHTVDFISFSYYSSRVSTTDNELLEQTAGNIFASV
                     KNPYLEASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDYR
                     IDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNEGNG
                     TLARSKKKSFNWYKKVIDSNGENLSND"
     gene            complement(10644..12047)
                     /locus_tag="IXR40_001563"
     CDS             complement(10644..12047)
                     /locus_tag="IXR40_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HAQ4361417.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPTMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEDNGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMNELFIAHQQYLPQFKETISRLKAEGIEVQ
                     DELARELSSNTHVMEEV"
     gene            12277..13179
                     /locus_tag="IXR40_001564"
     CDS             12277..13179
                     /locus_tag="IXR40_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAQ4361418.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQEIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIQDTLSLIHHDQLQKAKQLMLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNHVPILALTSIGDST
                     LSSMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVD"
     gene            complement(13220..15106)
                     /locus_tag="IXR40_001565"
     CDS             complement(13220..15106)
                     /locus_tag="IXR40_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4361419.1"
                     /translation="MGKYQELASKIVENVGGKENINGLTHCITRLRFKLKNEEKANDE
                     ILKNMDGVVTVMRAGGQYQVVIGNHVPVVFEEVIKAGNLTFDEAVSTEKMRPFDMLID
                     GISGCFQPFLAILAAGGMIRGLTALLVFLGAFDRGSGTFVMFDNIGDSVFQFMPVIIG
                     LTAARKFKVNEFVGMLLGAALMNPSLSLEALSGAAEAPLTTIFSGTIFEAPIYQTVFG
                     IPWIARNYASSVIPIIFIVLLASQIQKPIKKLVPEMIANFFVPFFTVLITMPLGFLLV
                     GPAFTFATDILMAGFETLLALSPVIYGAIVGFFWQILVMFGLHWAIVPMGLMQFSVNG
                     WQNIMTPVAVVSFGQTAALTALYFKLRNPKDKAIAIPAIVSGIVGITEPAIYGFTLPR
                     KKIFIFTCVGGALGGAYSGLMNLTSWNPGGLGIFTIPNYIRPDGDLTDVINVLIGIAI
                     AMVVSFALTFFFWKEEAGETDDRQKRSGKEIVKTPIQGQIAPLNAAKDAAFAQGTLGR
                     GILIYPEKGEVRAPFDGTVMTLFPTKHAIGMVSEAGLELLIHVGLDTVQLEGKYFESL
                     VQQGERVKQGDLLLRFDKKKIEEEGYSLETPVIVTNYTDYLDILENQGETVGPDDALI
                     TALT"
     gene            complement(15203..16054)
                     /locus_tag="IXR40_001566"
     CDS             complement(15203..16054)
                     /locus_tag="IXR40_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAQ4361420.1"
                     /translation="MLIEKVLNNNVVITRDERNQEMIVMGKGLAFKKKVGDPIFDSCI
                     DKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEALQVQLNDSVYIALTDHLY
                     TAIERHKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDEAGFIALHL
                     VNAQGIQSQQDNTYLFTTTIQDILNIVRYYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GEKSEVGEVSEELYQVIQKKYKDTFGCVEKIADFLAEIFNYQMSTDEKMYLTIHIARL
                     VHENRCK"
     gene            complement(16512..18296)
                     /locus_tag="IXR40_001567"
     CDS             complement(16512..18296)
                     /locus_tag="IXR40_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4361421.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGMYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYVRVRLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFIAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     ALTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSTFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQAITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPTITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLTKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGV"
     gene            complement(18296..20047)
                     /locus_tag="IXR40_001568"
     CDS             complement(18296..20047)
                     /locus_tag="IXR40_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAQ4361422.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGIFSLFAVALVQLAPPKVIGIIID
                     EIADKNLSIKIISWWILLLILAALLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGCSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     RMWEKQKLEAKIEGGEA"
     gene            complement(20189..20413)
                     /locus_tag="IXR40_001569"
     CDS             complement(20189..20413)
                     /locus_tag="IXR40_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HAQ4361423.1"
                     /translation="MVSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            20664..22250
                     /locus_tag="IXR40_001570"
     CDS             20664..22250
                     /locus_tag="IXR40_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HAQ4361424.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVTQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQDEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHTALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFVVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADQIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQRLQETIEEIE"
BASE COUNT         6378 a         4861 c         4028 g         7354 t
ORIGIN      
        1 gtatcattcg tcttatcgat caattcgaat aattgcttga tccgattgtt ctggtcatct
       61 gccagatctt tttgataagt atattctgga gtcactgctt ctgctgccag ttttcttctt
      121 tgttcggttt cttccgtgtt ctcgatcgtt ttattcgcac ggatactctc ttctgctact
      181 tggccttctc tgaaatcatt ggccttttgt ttgacactac taaatgtaac gccgcagaca
      241 atgataaaaa acaagaacag aaggaaaggc aatgctgcct ttccgagttt ttcttgtagt
      301 ttctgcagtg ttttattcaa catgtgctta tcctcctaag caaagcttat tcttgatgaa
      361 gatccgcctt ttcataagct ttgatgattt cggcaactac agggtgccga acaacgtcac
      421 ttgcttcaaa attaacaaaa tcgatttttt tgatttgctt tagtgttcgt tctgcatgaa
      481 caagaccact tgtcgtccct cgaggcaagt ctatctgact tgtatcccca ttgacaatca
      541 tttttgattg ataaccgaga cgggtcaaga acattttcat ctgagcgact gtcgtgtttt
      601 gtgcttcgtc caagataacg aatgcatcat ccaatgtccg cccccgcatg taagctaatg
      661 gtgcgatttc gattacgcct cgttccatca atcggttcgt atgatccaat ccaaaaattt
      721 ggtataaagc atcataaaca ggccgcagat aaggatccac tttttctttc agatccccgg
      781 gtagaaagcc taggttttcc cctgcctcta cagcgggccg cgtcaaaatg attttttgca
      841 cttcgccttt ttttagggca gcaattgcta atactacggc aagaaacgtt ttccctgttc
      901 cggctggccc tacaccaaat acgatgtcat gtttggctac cgattcaacg tatttctttt
      961 gaccgctgtt ttttacccgt ataggttttc cattacggtc tttgacgatc tcttcctcat
     1021 acatctcaac aaaataatct aatgtacctt tttgccccat tttcaatgcc gtcacgacat
     1081 ctggtgtact tacgtggatt cctcgtttga tcaattcctg taatgtccga atgactgagg
     1141 cagccaagga aatctgggat tgttcaccaa tgatctgaat gatttctcca cgtgtatgga
     1201 tggttgtttc cgttgtttcc tcgatcagtt ttatatgctt gtcgtgtgca cctaaaagca
     1261 tgctgacatc atcagcagct gtcaatctaa tctctaaaga actagactct tccgtcaaaa
     1321 atagacatcc cctttttttc gattcattct ttcctatttt accatactca gaagaaacta
     1381 tatagcaaat aagaaaaggt tgtaaaagag tcgtttaacc atacgtacca agaaacgtta
     1441 aaaaatagct gtttccattc gctaaaggtc tcgttttgat aaaaagaatc tgagaatgta
     1501 agttatatga aagtggagaa caaaatattc cgtttcattc agaggtattc tctaggtatt
     1561 tttcttgttt caaaaaaaga aaacaaaata gttaaaatat tcttgcattt caaaaaaaac
     1621 aggtgtatta ttacgtcaac aaataaacat acagcaaagc gtcgaggaaa acagtaggct
     1681 attcaacgat ttattcccag tgagtcatgt aagtgagaaa tgacaataaa tcgaatagac
     1741 gaacatcatt tccgagtcaa tgtcgaaaac gtagatcatt gtggctgcct ccattatcag
     1801 gctagcggat aactttatca aaaagcgtcc gtgaatgaag aagctttttt aagcgaaaaa
     1861 aggtggtacc gttctagaat ctagagccct tttcccaagt ggaaaagggc ttttttttat
     1921 attttaaggt ggtggttttc atggaatctg atattagtgg cattactaat tgctgcaacg
     1981 tttatatcgt caatcaaaat gataattatt ggaggaaaaa tttatggaag aaacaaaaac
     2041 ttattcatgg aaacaactat tgatggtcag ttcacttatc ttcgggatgt ttttcgggtc
     2101 aggtaatcta atctttcctg tccacttagg tcaaatggct ggcgcaaact gggtcagtgc
     2161 tggcgtagga tttgccatct caggcgctct tttcccatta ctagctatct tagctgtagt
     2221 agtgacaaaa agtgatggtc tgtatgactt agctaaacct gtcggaaaat ggtatgctgc
     2281 cttgttctta atccttgttc atttgacgat cggaccattt ttcggtacac cacggacagc
     2341 tgctactgct tttgaaatgg ctgctaaacc atttttgcct gaaaaatata attcattagg
     2401 tatgttttta ttctctgctc ttttcttttt acttgcttat ttccttactg tccatcccac
     2461 acggttggtc aaatacgtcg gaaagtatct aaactccttg tttcttgcat tattagcaat
     2521 catttttgtc gtttctttat tccacccaat gggaaatcta aatcaatctg ctgcagatac
     2581 ttaccaaaca aacgctttaa caaatggtgt cctagaaggt tataacacgg ttgatgcagt
     2641 agccttgctt gccttaagtg tcacttttgt ccatgcagtc cgtgaccttg gtttcaaaga
     2701 taaaaaagtc acagaattaa cagcaaaagc tggtagcctg agcgttgcgc tagaagtcat
     2761 gatctatttt ggtcttgttc ttctcggtgc gatgagtttg aataagatgt ctttatcaga
     2821 aaatggcgga actgcacttt ctcagatcac taatttttat ttaggtaact tcggcgctag
     2881 cttcttagga gtgatggtca cattaggtgt cttcactacc gctatgggac tcgttgtttc
     2941 ttttgcacaa gatttccata aactgttccc taaagtcagt tatatgacat ggctgcggtt
     3001 aacgactttc gtctcttttg tcgttgcaaa tgctggtttg gacaatatca tccaatggtc
     3061 tttaccagta ttgatgcttt tgtatccatt gtcgcttgcg ttgattttgc tttccttaac
     3121 agcaaaattt ttccaaaaga caccatttgt ctatcaagta acgatgttgt ttgctgctgt
     3181 tcccgccgta ttggatatgc tggcaaattc gcctgcttta gtgagtcaac aaagagttgt
     3241 agcaagcatg ctcgaatttt atcatcatca cgttcctttt gctgcattgg gacttggctg
     3301 gatggtccca acgttacttg ggtatgctgg cagcttactc ttctattacg cctatcgcct
     3361 atcagggtat aaacaagaag caaatgaact accagaagaa taaccagatc aaacacaatt
     3421 taacataaga aatattaaac aggaaaaaaa cagctagatg aaagaatcct attctttcgt
     3481 ctagctattt tttagatctc ttttttacga gcacaaaaaa actgcggaca atgattgtcc
     3541 gcagtttaaa tgataaaatt aagattgtaa tagttctttc acaatggcat ttacttggtt
     3601 tccatctgct tttcctttga ctttaggcat gatcgcaccc atgactttgc caaattcttt
     3661 cattgatgaa gcaccagttt gcgtgattgc ttcttgaaca agttgtcgaa tttcttcgtc
     3721 ggaaagttgt tccggcatgt atttttcgac tatcacaatt tcacttttta ctttttcagc
     3781 taaatcgtca cgtcctgctt cttcaaactc atgcaaagaa tcacgtcgct gtttcatttc
     3841 gcgagacaac accgttaatt cttcttcttc tgtcaagtcg tgaccttctt taatctgctc
     3901 gttttgtata gatgacttga tcattcggat gacttgtaaa gattccttat ctttcgcttt
     3961 catcgctgtt ttcatgtcat cgtttaatct acttagtagt gacacactac caactccaat
     4021 tcatcacaga actagaattt tttgcgtttt ctagctgctt cagatttttt cttgcgtctt
     4081 acacttggtt tttcgtagaa ttcacgttta cgagattctt gtaaagtacc cgcttttgac
     4141 acggaacgtt tgaagcgacg aagagcatcg tcaagtgatt cgtttttgcg aacgactgtt
     4201 tttgacatgt taattccctc cctccgagct taaaaagtaa ccgtaattgt tattgaaata
     4261 tatctcaaaa aacaagactg tcctgtaaat attatatcta atgctgtttt gaccgtcaag
     4321 gaaatcttgc ttttttttaa aattatcaaa tgttatttta tttaaatcct tattgacaat
     4381 tttcacatct tccgaaaatc tcgaatctat gcccttcgat cgtacatcca ccgagctgtt
     4441 cttcgaaata attcattgga cacatatgga tttctttcgt tgttccgcac accgtacaga
     4501 taaagtgatg gtgatggccg atttcccctt gacagcaatg aaaacgaaac ttcatctctc
     4561 catttaaatc ggtttcttcc agtaaatcga tttctgcaaa atcatggaga tttcgataaa
     4621 tcgtatcgta acttactcct ttgaattcct gattcatata gtcaaaaact tctttagcgg
     4681 atacgtagcg attgcgcttc actaaataag ttaacaatgc ttctcttttt ttagtatatt
     4741 taaaaccgtt atttttcaat gtttctagtg attgttcgat caacgtctgt tttttcatga
     4801 cttattcctc caaatcaaaa tgattacgaa gtacacattc tagagtatgg tataataaac
     4861 ataaaaaaaa tgcaagtgag gttttatcca tgtcttccga ttctacagaa atcgttactt
     4921 tttttgtcat ctccgactct gctggagaaa ctgcgacaaa actagcgcaa gccactatgg
     4981 cccaatatcc tagcgttgag ttcaatttat tccgcagaac atttgtgaca gatgagaaaa
     5041 cattgatgca ggcactgcaa gatgcactag aagaaaaagc tcttgtcctg cacacattga
     5101 tcaatcaaga attgatcgag atgacgcgtt ctttttgtga agaacatcaa ttatttagtt
     5161 ttgatgtgat gactccgccg atatcagaaa tcgagcgctt aactggtatc aagcccattc
     5221 ggcaacctgg cgcccttcat ttattgaatg agaactattt caaacggatc aaagcaatgg
     5281 aatttgctgt aaaatacgat gacgggaaag atcctcgtgg gtttctagaa gcagatgtcg
     5341 ttttgctagg cgtatcccga acttccaaaa cgcctttgag cttgttttta gctaacaaaa
     5401 atttaaaagt tgccaatcta cctttgatcc cacaagcaca tattcccaaa cagctttggg
     5461 agatcgatcc taaaaaaatc gtgggactga cgaataaccc agatatttta aacaatatcc
     5521 gtaaagaacg gatgcgctct tacggattaa atcctgatac tgcttattcc gatatcgaaa
     5581 aaatacgagc tgaactcgat tttgcgaatg atctttatga aaaattgggc tgcgtagtaa
     5641 tcaatgtcgc ttctttatct attgaagaaa cagcttcgct tattttgaat gctttagacc
     5701 tagaagacca tagttattat ggaactgaaa ccaccgaaga aacagactaa caatttttct
     5761 ttaaaaaaac tggactgtgt cagcgaagaa gattcgttga cacagtccag tttgtctcta
     5821 tttgcaccta tcgttattga tgttccacat gtttgagtgt ctggttcaaa atatccagta
     5881 cgtgagaatc atcaagacta tacaaaatcg cttttccctc acgatgggac ttgacgacat
     5941 ggttttctct taataaacgc agttgatgcg atacagcaga ttgttccatt tccactgctt
     6001 ggatgattgc tgtcacattt tgttccccgt ctttcagata cagcagaatt ttgagacgag
     6061 tggggtcact caacattttg aatagttggc tgactttctc tacttttgtt ttttgcgtgt
     6121 ctggcaatcc attcacctcc aacttgaaaa aagactgact tctaaagttt accacttttt
     6181 ccatcagtct caagtttttt tattcttctg tcatcttttg gataatcgtt tcataagcgg
     6241 ctactttttc agctgcgtct tctgaagagt ttccttttac accgatataa aatttgattt
     6301 tcggctcagt tcctgaagga cggatagcga tccagccatt ttcttccagc gtatacttca
     6361 atacgtcaga tggcggtgtc gttagttttt ctacgtttcc ttcacggtct gttctcgtca
     6421 actctttgaa gtcttctgtt tggatgactt ttgctccggc aaattctgtt ggtgcttctt
     6481 cacggaattt ttccatcaaa gcagagattt tcgcagaacc ttcttgtccg ctcattgtca
     6541 cagaaatcgt tttttctgcg tagtagccat aggtttcaaa aatcgtttgc aagccatcat
     6601 acaacgtttt gccttgtttt ttatagtaag ctgctacttc tgctaataag agcaatgctt
     6661 ggatcgcgtc tttgtcgcga acgaaaggtt taactaaata accgtaactt tcttcgaatc
     6721 cgaacataaa agtatgggaa tgatcttctt caaattgttg aattttttca gcaatgaatt
     6781 tgaatcctgt caatacattg aacatggtag ccccatagtg ttccgcaatt gctgtaggta
     6841 attcgctaga aacgatcgat ttcaataccg ctgcgttttc aggtaaagtg cctcgcgatt
     6901 ggtgtgcttc caaaatatat tgagcaaaca gtgctccgat ttggtttccg gtcaatactt
     6961 cataggagcc atttggcaaa cgaacggctg cacctaaacg gtctgcatca ggatctgttg
     7021 caatcagcaa atcagcgcct tctttctcgc caagtcgtat cgcatactca aaagcagagt
     7081 gttcttctgg atttggtgat ttgactgtag tgaaatctgg gtctgcgaca gcttgttctg
     7141 gaactagtac gaattgttcg aatccagctt gtttcaacgc acgttcgccc aacatttttc
     7201 ctgttccgtg aagtggtgtg tacacaagtt tcaaatcttt ccccattgtt tccaccaatt
     7261 catgatcaat cgttactgct ttgatttctt ctagataagc ggcatccact tcttctccga
     7321 tgatcgtgat caatccgcta tgttcagctt cttcgtcaga taatacttca acttttaacg
     7381 gattgctgac ttcacggaca tatttcgtca atgcatctgc gtctgcagga ggcatttgtc
     7441 ccccatcttc tccgtagact ttatatccgt tgtaagctgc tggattgtgg gatgcggtta
     7501 ccatgattcc cgcaaacgtc ttcaaatgac ggactgcaaa agaaagctct ggtgttggac
     7561 gtagactttc gaatacataa gatgggatat tgtgatgtgc taatgttttg gctgcttcca
     7621 tggcaaattc tggtgattga tggcgtgagt cataagcgat agcgacacct cggcgttttg
     7681 tttcttcgcc ttgtgtatcc atgaaacgtg caagtccttc tgttgcttgt cttaccgtat
     7741 agatgttcat tcgattgatc ccaggcccta agattccccg catgcctgca gtaccgaatt
     7801 ccaacggtgc ataaaaagca tcttcaagtt tttcaggatc ttcacccaga tcatttaatt
     7861 gtttttttaa gttttcttct aaattttctt catgtaccca ttgttcatac acttgttccc
     7921 aagacatgaa aataacacct ctttctgaaa tatggttctt aataagtata gcattcactt
     7981 attagatatg aaagtatgag gaccaaaaaa cgcttaaatc aagaaaggat tcttttatca
     8041 agcacggttg caagtattcg cataaatcgg attcagtaga tttcacgcga aaaaaaagag
     8101 taaaagaaca attaaaccgt tcttccactc tttttaaact tatgcagttg tttcttctaa
     8161 agattccaag tatttataca cttgttgtcc agcgatccca ccatcaccaa cagcagtagt
     8221 gatttgtcgc aaatcttttt cacgaacatc tccgatggca aaaacgcctg gtatattcgt
     8281 cttcatttcg ttgtctgttg gaatccagcc agcttcgttc gtcaaccctg cttctctaaa
     8341 tggtgcagtt aatggatcca gtccaacata gatgaatact ccgtctgctg ccaaatcaaa
     8401 ctcattgccg gttttgacat tacgtgcttt cacacctgtc actaccattt cattcccaac
     8461 gatttcgtca acgactgtat cccacataaa ggaaattttt tcattcgcaa atgcacggtc
     8521 ttggatgatc ttttgtgcac gtaattcatc tctacggtgg acgatgacta cttcagaagc
     8581 aaattgtgtc aaatagatgg cttcttctac tgctgagtct cctcctccga tcactactag
     8641 acgtttgtta cggaaaaacg caccatcaca aactgcacag taagaaacgc cacgtccagc
     8701 aaattcttcc tcgccaggta cgcctaattt acggtggata cagcctgttg cgataatgac
     8761 tgtttttcct tcgtaagttt tatcttcaca aataacttct ttgtggctgc cgtgatcctt
     8821 gatatcttgc acgattccat aagcattttc tgtcccaaat cttgaaacac cttcatacat
     8881 cttataagct agatcaggac ccattattga atcgaaacca ggatagtttt cgatttctgc
     8941 cgtattgttc atttggccgc caggggcgcc ttgttcgatc atcaatacgg ataagtttga
     9001 acgtgaagca tataaagcag cagtcatccc agcaggacct gcgccaataa cgattacatc
     9061 atacatatgt agattctcct ttacttaatc aagtaagcat actttacagc caatgcgaaa
     9121 aaaagtctat tgttctgctt gcgtttctcg aatagcttta ttatactcga aaaatccgct
     9181 gaaaaacaat agacttttat aaatcattga tcaatcattc gaaagatttt ctccatttga
     9241 atcaattact tttttatacc agttgaatga tttcttcttc gaacgggcta atgtgccatt
     9301 tccttcgttg tcacgatcga cataaatgaa tccgtacctt ttcttcatct cacctgtacc
     9361 agctgatact aaatcaatac atccccaagt cgtatagcct aatagatcga ctccatctaa
     9421 ttctactgca tctttcattg cctggatatg tgctgccaga tagtcgattc gatagtcatc
     9481 ttccacataa ccattctcat cgggcgtatc gactgcacct aagccgtttt ctacaataaa
     9541 tagtggtttt tgataacgat cataaatatc attcatcgtt attctcaagc ctaatggatc
     9601 aatttgccaa ccccattcac ttgcttccag atatggattt ttgacagaag caaagatatt
     9661 tcctgcagtc tgttccaaga gttcgttgtc agtagtcgaa actcgagaag aataataaga
     9721 aaaggagata aaatcaacag tatgttcttt cagcaatgcg gcatccccag gttccatttt
     9781 gatctgaatg ccatttcgtt ccatttcttt caatgcataa gcaggatatt ctcctcgtga
     9841 ctggacatca atgaagaaat aattttctcg atctgatttt ctagaagccc aaacatcttc
     9901 aggattgcaa gtgtatggat aatatgctcc tgctgccagc atacagccta ctttgttctc
     9961 cggatctact tcatgagcaa tcttcgttgc gatggcactt gcaaccaact catgatgtgc
    10021 cgcttgatat ttgatttgtt cttcattttc tccttcttca aaatacagcc ctgcgcccat
    10081 gaatggtgca tgaaggatca tattgatctc attgaatgtc aaccaatatt tgacaagtcc
    10141 tttatagcga ttgaagatga ctcggcacag attttcataa aaaccaacga gttctctgga
    10201 acgccacgca ccatattctt tgatcaaatg catcggacaa tcaaaatgtg taatcgtcac
    10261 aagcggctcg atcccgtact tttgacattc tttaaagaca tcctcataaa atttcaaacc
    10321 agattcattt ggctcttttt catcgcccat tggaaaaata cgactccaag caatggacat
    10381 ccgataagtc ttgaacccca tttctgcaaa taaagcaata tcttccttat aatgatgata
    10441 catatcgatc gcaatttttg ctggataaaa atgattttca tcaaattcaa acattttctt
    10501 ttttccagta atgacaggaa aacggtcttc tccgattggc acaacatcta cgttcgctaa
    10561 cccacgtccg ccttcatcat aaccgccctc gcattgattg gctgctgtag ctccgcccca
    10621 taaaaaatct tttctgaatc ccatcatact tcctccatta catgtgtatt gcttgataat
    10681 tctcttgcca gttcatcttg gacttcgatt ccttctgctt ttaaccggct gattgtttcc
    10741 ttgaattgcg gtaaatactg ctgatgtgca ataaacaact cattcatgat ccgttttgct
    10801 gtctttcctg atcgtataag cggattgatc gtaaacgctt gtaaagctgt tccataatca
    10861 ccagtcacag ctgcttcgat cgtcagcaat tccatattct tcattacttg caaccagcct
    10921 ctttcagcag caggaaggga accaaacgct acatttcgtg cgccttgtgc gccaacatag
    10981 gcagtgactt ctactacaca atctgccggc agatcaggaa cagctccatc attctttgta
    11041 gataccacga tctgtgtttc tttatttcca tagatcgaag caatcgtttc acaggcagca
    11101 tctgaataat aagcaccacc tcgtttttgc aattgttcag gtttatgatc caattctgga
    11161 tctttgtata attcaaacag ctctgcttct gtttctttca cttgctgcgc tcttgtacca
    11221 atcgtttgat attcttctaa agcatgttcc agcatttctt cttcacggta gtaatagcgg
    11281 tggtagccac aagggatcat gttcatttgt tttaattgtt ctttgaaaaa cgggatatca
    11341 aagatatttt tcggcaatcc attgtcttca tcgtataaac gatcaatcaa ttctgccgtg
    11401 cggtcatttc ctttattatc tgctactttg tgccaatgga agtgatttag accggcaaac
    11461 ttgtagatca gctcttcttt tttcttgcca agcattgttg gttctgtcat catcgccatt
    11521 actggcacat tgcataatcc tatcacttta tcccatttgc catatctgat aactgcttct
    11581 gtcaccatcc cgcttgggtt cgcgaaattg atcagccaag catttggaca taaacgcttc
    11641 atgtcttcaa cgattgccaa aaccactgga acggtacgaa aagctttgaa tatcccgcca
    11701 gcaccatttg tttcttgccc aatcatccca taataactag ggatccgctc gtctttgatt
    11761 cgtgcatcta attgaccgac acgaaactga gtcgtaacaa aatccgcatc tttcaatgct
    11821 tcttcccgat ccagagttgc atagattttg acttcatacg gagaagcatc ccacatacgc
    11881 tgagacatct gactgacgat ctcaagcttt tcttttcctt cttctacatc tacgagccag
    11941 atttctcgta tcggtaattc ctcatatctt ttgataaatc cttccatcaa ctcgggggtg
    12001 taactgctgc ctccaccaat cgtagcgatt ttgattcctt ttgccatgtt ctcactcctt
    12061 tactttttac acttttatta tcttttttgt aaacaaaaca aacaatagaa attcgtttct
    12121 ttccagtaac atttacaaaa gttagtgttt tctactggat ttttgtaaat atcttgtcaa
    12181 aaaatgtctt tattaagcta tataacataa atccgtttac aaatcatttt caaaaaagtt
    12241 ataatttacg taaaaaaaca agaagaaggt atctacatgt tattacgtga aaaaatcaaa
    12301 gaaatctcct tttctccttc agaaaatgaa gtgattcagt ttctcttaag cgattctcca
    12361 gcacttggcg aaatgaccat ccaagagatt gctgagcgat gttatgtcca cccgtccaca
    12421 ctcatccgtg tagcaaaaaa aatgggtttt gatggctggg tcagttttcg taatgctttt
    12481 ttagctgaaa cagcctatct tgaagggaat tttcaagacg tagatgcgaa tcttcctttt
    12541 tccaccacag acggtattat gacgatcgca aataaaatgg cttctttaga acagatgacg
    12601 attcaagata cactttctct cattcatcat gaccaactgc aaaaagccaa acaactaatg
    12661 cttcaagcaa aaaaaatcgt gattttcgcc agtaactcga atactttgat ttctcaagat
    12721 ttcatgctga aaatgaagcg catcaaaatg gatgtcacga ttgtcaccac ttttggtgaa
    12781 tcgttctatg aagcgtacaa ttgcacgagt gatatgtgcg ggattctgat ttcttatacg
    12841 ggtgaaaaca atgtgatcct tcgtaccgca gaaatattga aacaaaatca tgttccaatt
    12901 ttagctttga ccagtatcgg tgattcaacg ctatcttcaa tgagtacagc cgctttgcga
    12961 cttacgacac gcgaacgact gtattcgaaa attggtaatt ttacgatcaa tacatcgatt
    13021 tgttatcttc tagacgtgtt atatagttgt gtttttgcag aaaattatca acagaattta
    13081 gtccatctaa tttctgtagg acaaaaattt gataaacgcc ctatcagctc agccatcatg
    13141 aaagagcctt tcaattttga aaataaagaa gtggactaaa aagaataatt aagcctagtc
    13201 cattctttca cctaaccgtt caggtcagtg cggtgataag tgcatcgtct ggcccgaccg
    13261 tctccccttg attttccaaa atatccaaat aatccgtgta attggtgacg atcacaggtg
    13321 tttctaaact gtatccttcc tcttcgattt tctttttgtc gaagcggagc aacagatcgc
    13381 cttgtttcac tctttctcct tgctgcacca agctttcaaa atatttccct tccaactgaa
    13441 cagtatccaa tccgacatga atcagcaatt ccagacctgc ttcagaaacc attccgattg
    13501 catgtttcgt cgggaacagg gtcatgactg ttccgtcaaa aggggcacgt acttctcctt
    13561 tttcagggta gatcaagatt cctcgaccta gtgttccttg tgcaaaagct gcatcctttg
    13621 ctgcattcag tggagcgatt tgtccttgta tcggtgtttt tacaatttct ttacctgatc
    13681 ttttctgtct atcatctgtt tcacctgctt cctccttcca aaagaaaaaa gtcagcgcaa
    13741 aggataccac catcgcaatg gcgattccaa tcaatacatt aatcacatcc gttaaatcac
    13801 catctggtct aatatagttg ggaattgtaa agatgcctaa tccacctgga ttccaagaag
    13861 ttaaattcat taatccacta tacgcgcccc ctaacgcacc accgacacag gtaaaaataa
    13921 atattttttt acgtggcaat gtaaacccat aaatagctgg ctctgtaatc cccacaatac
    13981 cagaaacaat ggctggtatt gcgattgctt tgtcttttgg gtttctaagc ttaaagtaga
    14041 gtgcagtaag tgctgcagtt tgtccaaaag acactactgc aacaggtgtc atgatatttt
    14101 gccaaccatt cacagaaaat tgcatcaatc ccattggtac gattgcccaa tggagaccaa
    14161 acatcactag aatttgccag aagaagccta cgattgctcc ataaataact ggcgaaagtg
    14221 ctaaaagtgt ttcaaatcca gccattaaaa tatcagttgc gaatgtgaat gctggtccaa
    14281 cgagtaaaaa acctaagggc attgtaataa gaacggtgaa gaatggaacg aagaaattcg
    14341 cgatcatctc aggtactaac tttttaattg gtttctgaat ttggctagct aacaacacaa
    14401 taaagataat gggaatgaca gaagaagcgt agttacgcgc aatccaggga atgccgaata
    14461 ctgtttgata aataggtgct tcaaaaatag tgccagaaaa tatggtagtc agtggtgctt
    14521 ctgctgcacc actcaaagct tccagcgaca agctaggatt cattaatgct gccccaagca
    14581 acatccctac gaattcattt actttaaatt tacgggcagc tgttaaaccg ataataacag
    14641 gcataaattg gaatacagaa tcaccgatat tatcaaacat aacaaatgtg ccagaaccgc
    14701 ggtcaaatgc gcctaagaag acaagtaatg ctgtcagtcc acgaatcatc ccaccagcag
    14761 ctagaatagc aaggaatggc tggaaacagc ccgatattcc atcaataagc atatcaaacg
    14821 gtctcatttt ttctgttgaa acagcctcat caaaagtaag gtttcctgct tttataacct
    14881 cttcaaacac gactggcaca tgattcccga tgacaacttg gtactgtcct cccgctcgca
    14941 ttaccgtcac aacaccgtcc atatttttca agatctcatc atttgctttt tcttcgtttt
    15001 ttaatttgaa acgaagcctt gtgatacaat gtgtcaaacc attgatattt tccttcccgc
    15061 cgacattttc tacaattttg ctcgctaatt cttgatattt tcccatttct attccctcca
    15121 atttattagt ggaaggttta gccaactgaa tgtcactacc cttatttcat gcgttcttgt
    15181 taatttatcc tccttttttt atttatttac aacgattctc atgcactaaa cgcgcaatat
    15241 ggatcgttaa atacattttt tcgtccgtgg acatctggta gttgaatatc tcggctaaaa
    15301 agtctgctat tttctcaacg caaccaaacg tatccttata ttttttttga ataacctggt
    15361 acaattcctc agaaacttct cccacttctg atttttctcc atctaggacg cgtgtcagaa
    15421 aaaaacgtag gtgtgtgacg aatcgaaaaa aatggactga atcttcatca aatgtaatct
    15481 tatagtaata gcggacgata tttagaatat cctgtattgt tgtagtaaac aggtaggtat
    15541 tgtcttgttg gctttgaatg ccttgtgcat tgactaaatg caatgcgata aatccggctt
    15601 catcttctga taacttgatg tggtatttat ccgagatttt cttcactgtt tttttcccga
    15661 tggcatactc tttaggaaat agttgtttga tatcatacag caatacattt ggtacaaata
    15721 ttcccatttt gtgacgttcg atagccgtat acaaatgatc cgtcaatgca atatacaccg
    15781 aatcattcaa ctggacttgt agagcctctt ttgtatattc aatgatttca caagaaattt
    15841 ctaagtactc aagaggaatc gcttgtgcca attcttggaa ctgttgtgaa agtccgtcat
    15901 ttgtcaactg aaattttttg tcgatgcatg agtcaaaaat cgggtcaccc actttctttt
    15961 tgaatgccaa accttttccc atcacgatca tttcctgatt tctttcatcc ctggttatta
    16021 cgacgttgtt attcagtact ttctcaatca gcatgtttta ctcctttcca tgatatatag
    16081 ggctgtatcc aaaacaaaaa gaaaaaccca aaaagccgtc catggaacca tgggagactc
    16141 atcaggttta gcttgcatca ggcaatcact atccaagttg tatcgttttc tttatattat
    16201 cgaaagcaag cacttttgtc aacgctttct tagcggctat tgggcacttc tgactagctg
    16261 tcgtgatttt ttttaaatct ggtaattacg acactaacgc tcacagatga agaatctggg
    16321 aagctctgtt ttattttcac tctagcgctt aggtcaaaat gctactatgc tactgtccca
    16381 acttctaata tacggtgttc cagtaccagc ttatcggtga taagccaaat ttatgcaaaa
    16441 atctggaaag ccttttttac aatttttttc ttatcaccta aagctgaacg gagccctgtc
    16501 acaaccactt tttacacacc actgctttgc agtttgtaca tatctgcata caaaccattt
    16561 tgcgctagaa gtgtttcatg attcccacgt tctactatat gacctttgtc taaaactaaa
    16621 atcaattctg catcccgaat cgtggacagc cgatgggcaa tcgcaatcgt tgtccgtcct
    16681 tgtcgcattt ttgtcaatcc ttcttggatc aatccttctg tttcagtatc gatatttgct
    16741 gtcgcttcat ccaatactag tattttagga tctgtcacga ttgttcgcgc aaaagtgatc
    16801 agctgtcgtt gtccgctaga atagctggca ccgtgttcga tcacttttga gtgatatcct
    16861 tttggtaatt catcgatgaa cttgtttgct tgaacaaact cagctgcatg gcgaatctgt
    16921 tcgtctgtga tagttggatt catcatccgg atatttcctg cgatatctcc ataaaacaag
    16981 aaggcatctt gcaagaccaa tcccattttc ttacgtaact cttccattgg atattctcga
    17041 atgtcatgat catcaatcaa gatctggcct tcataaaatt cgtaaaaccg catcaatacg
    17101 ttgatgatcg agctttttcc gcttccggtg tgccccacta atgcaacggt ctctcccgga
    17161 ttagcgacaa aagagatatt gttcaataca ttgtgctctc catcataaga aaagcttaca
    17221 ttgcgaaact cgatcttacc tgaagtaatc gcttgatctg ctccaggatt ttgttgcggt
    17281 gcatattctt ctgtatccat gattttcaaa atacgactac cggcaaccat tccatctgta
    17341 aaggtgctca aaaagtccat catttgagac attggattaa aaaatccctg gacataggtc
    17401 gtaaatgcat agatcagtcc aacttctacg ggagaatgca gcgcatcgat cccaaacaaa
    17461 gtcaacgcca acgcaatcgc caatgcatat agaaaattga tgatcggact taacagaatc
    17521 gaatttgttt tgatcatcgc atagcgcgtg tctaaatact cgttgttcac ttgttcaaat
    17581 tctttagcta aacgagcttc ttggcgaaac tgctggataa tacgcatgcc ggaaatcgat
    17641 tcattcaatt tcgtgttcag ctgacttaat ttttcccgca tattccggta aatacgagaa
    17701 ctgaatttct ggtaatacca gatgacgatt cctaaaatcg gcaagaacac caaagtccac
    17761 aaggcaattt ctccattgat ttgaaacatg gcaatgaagg aagaaacgac tgcaaagatc
    17821 ccagtcaata ccatcaaaaa gacataccaa aattcaaata gcgtttctgt gtcatttgtc
    17881 actcgagaaa cagtcgatcc tgccggtgtc tgatcaaaat aacgcatacc tagtgtatgc
    17941 agcttttcaa ataatcttac ccgaacatac tgataggtct tcaatgaagc catggaatac
    18001 aaataccatt ggaaaaacca aatgatactt ttgactatga ctccaaacaa gtacatacca
    18061 gcaaaaaaca aaataacttg tgtcgtagcc gactgtttag ccagatgatc atccataaaa
    18121 gtttggatga tccttggcaa taggacattg atcacagaca gggcaaacgc aaataagata
    18181 gcaacgatga acgttcttct aaaaggtttg gcgaacttca tcagtcgttt gatgatcttc
    18241 ttctgttctt taagtggaat cgattttgtc cattccgatt gataattttc atccatcagg
    18301 cctcgcctcc ttctatcttc gcttctaatt tctgtttctc ccacattcgt tcataccagc
    18361 cgcctaatgc aagcagctca tgatgggttc ctcgttcaat gattttccct tgatcgacaa
    18421 caatgatttc ttttgcatgc atcacgctgc ttaaacggtg agctgcaatg atggttgttt
    18481 tctcttttct tatttctttt aaattatgca agatagcttc ttctgttttg gcatctactg
    18541 cagaaagtgc atcatctaag atcagcaatt caggattttt gatcaatgct cgagcaatcg
    18601 aaatcctttg tttctgtccg ccagataaag agactccacg ttctccaact aaggtatcat
    18661 aaccttttgg taattccttg atttcattgt tgataaatgc taaagaagcc gcatgctcta
    18721 cttcttcttc tgaaagtttt ggattagaaa aacggatatt atctcgaatg gtcatcgaaa
    18781 acaagaagtg atcttgaggc acatagccga ttgatcctaa taaagcattc aatgaatatt
    18841 ctttgatcga acatccgcca aattgaattt ttccttgata atcatcgtat tcacgcatca
    18901 gtaatttgat gattgtcgtt tttcccgcac cagttttccc aacaatacct aatgtttctc
    18961 cttcttggat cgcaaatttg atttgttcta atgctggtga ttcttctttc ggatagttaa
    19021 aagaggaaat agctacattc agctcgcctt ttgccggagt ctgcactgca cccagttgtt
    19081 ccacgatatg cgtcttttca tgcaaaagtt cattgacgcg atcataagaa gcatttcctc
    19141 tttccaatac gttgaacaat cgaccaatcg caaacatcgg ccaaacaagc ataccgatat
    19201 agctaataaa tgagaccatc tgcccgattg agatcgtgcc ttccaagaca tactttccac
    19261 ctaaaataat tgttgcaaca taagacagac cgataatcaa ggtaatgaat ggatcaaata
    19321 aggagtctaa aaaattgact cgtttgtttt taataattgc atcttcaatc ttttcttcaa
    19381 aatccgcgag atcttctttt tcttgtccaa atgttttaat gactttgatc ccagtaatac
    19441 tttcttgtgt cttatcattg atactagaaa aagcttcttg cgaatcacga aaagcatcgt
    19501 ggagttttga ccccagcact cgtgaagtaa cggctagtaa aggcagagga atcagcgcaa
    19561 tcagtgttaa gcgccaatca ataaacaaaa tcatcgcaat gatcgttgtt ccgcccgtga
    19621 tcactgaatc tgcaaaggtc aagataccag ctcctgctac attttggatt gcattcaaat
    19681 cattcgttgc atgagccatc aaatctccag tccgatattt ttggtaaaag agattgtcca
    19741 tttctgtaaa atgtttgaat agctgctgcc gaagttcttt ctccaaccga gctgcacttc
    19801 cccaaatatt cgtccgccag atataacgaa aaagatattg taagagagct gcaaggatca
    19861 ataataagat ccaccaggaa atgatcttta ttgataaatt tttatcggcg atctcatcaa
    19921 tgatgatccc aatcactttt ggaggagcta actgtaccaa ggccactgcg aatagggaga
    19981 aaatcccaat taaataatgt ttcttttcct gtcgaaaaaa ccaacctaat tttctaaaaa
    20041 tcgacatttt actcctcctt tgtctttatc aagagcatag gattgtctgt gcttgtcttt
    20101 tttgctgaat agtctgaata gtctaacaaa ttacgaaata aaaaacggac tgaaaaaatc
    20161 agcccgcaaa aagtctttgg gtcagaacct attttttccc ttggttcttc atttgctgca
    20221 tcatctggcg aattttcttc tcagatggtt tttgccccat tgacatcatc attgatcgca
    20281 acatgtcctc attaacggga ggattttttt ctaaatagtc tttcatatat ttacgcgcta
    20341 ggaaaaagcc acctactgcg ccgattagca aagcaataat agcaataagt acgacaatac
    20401 ctgttgatac catataaatc tctcctttct atttccgaat tgctctcaat gatttatttt
    20461 actaaagttt attgaaaaaa gaaaggcgta ttctttagtt tcatgcaaaa aatagtggtt
    20521 tttttagaga agaacaaaat ttctttcatt aaccagcaag acacgccacg aaaaaaaatt
    20581 aggcatacca aatctttttc tttaattttt tctttctgag gtgtagaatg taatcgtaga
    20641 taaataggaa aggtggtttt ttcttgaata atcaatccaa caaacaattt cataagcatc
    20701 gacttattga acatacaaat ggtttatctt tagctgaagt aaatggaaca gtggatgtac
    20761 ccaagggaaa aagttttttt aaaacacttc ttgcttactc tggaccaggt gcattagtag
    20821 cagttggtta tatggatcca ggtaactggt ccacttcgat cactggtgga caaaatttcc
    20881 aatatttatt gatgtcagtt attttgatgt ctagtctgat tgctatgctt ttacaatata
    20941 tggcagcaaa attaggaatc gtgacccaaa tggatttggc ccaagcaatc cgagcacgga
    21001 caagtaagac attgggtgtc attttatgga tcttgactga attagccatt atggcaacag
    21061 acatcgcaga agtcattggt gcagcaatcg ccctctacct gctttttgat attccattgg
    21121 taattgccgt atttatcact gtgttagatg ttttcgtcct tttattgctg acaaaagtcg
    21181 ggtttcgtaa aatcgaagct ttggttgtct gcttgatttt cgtcatttta ttcgttttcg
    21241 tctatcaagt tggcttgtct aaccctgatt ggcacagttt gtttgccgga tttatcccta
    21301 acagtcacac attctcagac tcaccggtca tcggcggcga aactccgctg actggagctt
    21361 tagggattat tggtgcaaca gtcatgccgc ataacttata tcttcattca gcagtttctc
    21421 aaactcggaa gatcgatcac caagacgaag aagatgtagc acaagcggta cgcttttcta
    21481 cttgggattc taatatccag ttgtcaatgg cttttctagt caatgcactg ctattgatca
    21541 tgggtgtggc tgtattcaaa accggttctg tccaagatcc ttcctttttt ggtctgtatg
    21601 aagctttatc tgatccatca gctatgagca atggtatctt gattgctgta gcaaaatctg
    21661 gtatcttgtc tactttattt gctgtagcac ttcttgcttc tggccagaac tctactatta
    21721 ctggtacgtt gaccggtcaa gtcatcatgg aaggcttcat ccatatgcgt atcccaattt
    21781 ggctaagaag actagtcaca cgattgcttt ctgtgattcc tgtattgatt tgtgttttgt
    21841 ttacaagtac aaaaggaacg atcgaagaac ataccgcttt gaataacttg atgaatgaat
    21901 cccaagtttt tctggctttt gcattgccat tctcgatgat tcctttactg atgatgacca
    21961 atagccaagc ggagatgggg agccgattca aaaattcatt tgttgtaaaa ctacttggct
    22021 ggttctctgt gattagtctg acttacttga atttacgagg attaccaggt caaatcgaaa
    22081 gtttcttcgg cgagcaagcc acctcagctc aactagcatt ggctgatcaa atcgcttatg
    22141 taatcattgt tcttgtcctt ctcctgttgg catggacgat tggtgattta tataaaggaa
    22201 acaaaaaata tgaacagcgt ttgcaggaaa cgatagaaga aatcgagtag aaactgattc
    22261 ttttacacaa aggaggttgt gtcagaagtg ggcagcttca agaaataaga aggaatttaa
    22321 gaaaattgct tttcaaattt ttgtgaaatt tcggcttatt tccgaagaag ttacttctgg
    22381 aacaccgtgt atcagaggtt gtgaaaaagc tgccttgcat caagtaataa gaacagccaa
    22441 gtaaaaacag ctttttatgt ttttaacttg gttggactta ttaccgcaga tgcaagcttt
    22501 tgagcaccgt ttattcggaa aaaggaactg cgacaagact tttgtcacag ttccctttcc
    22561 tacgattagt caagtaaaag gtgtaagaaa aatagctcat aaacgaaagc gacaaaatca
    22621 a
//
LOCUS       DACGEU010000044        21581 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.044, whole genome shotgun sequence.
ACCESSION   DACGEU010000044 DACGEU010000000
VERSION     DACGEU010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21581)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21581)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21581
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.044"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            262..963
                     /locus_tag="IXR40_001571"
     CDS             262..963
                     /locus_tag="IXR40_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HAQ4361425.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
     gene            complement(1572..2588)
                     /gene="tsaD"
                     /locus_tag="IXR40_001572"
     CDS             complement(1572..2588)
                     /gene="tsaD"
                     /locus_tag="IXR40_001572"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HAQ4361426.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIIAGGVAANQ
                     GLREGLQDALAAKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(2585..3049)
                     /gene="rimI"
                     /locus_tag="IXR40_001573"
     CDS             complement(2585..3049)
                     /gene="rimI"
                     /locus_tag="IXR40_001573"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HAQ4361427.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLAEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(3056..3598)
                     /gene="rimI"
                     /locus_tag="IXR40_001574"
     CDS             complement(3056..3598)
                     /gene="rimI"
                     /locus_tag="IXR40_001574"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HAQ4361428.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTVEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(3582..4406)
                     /gene="tsaB"
                     /locus_tag="IXR40_001575"
     CDS             complement(3582..4406)
                     /gene="tsaB"
                     /locus_tag="IXR40_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HAQ4361429.1"
                     /translation="MYYCTSFAFGIFILRIKKYATMEGENVIAERIKYMITLGIDTAN
                     QTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAIDQLFADLQISPKDIDRIAVSDGPGS
                     YTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAANCIGVDNIIVPMFDARRKNVYAGAY
                     RWKENRLETVLEDVHISASDLFTQLQKLNEAIYFVGSDCHKFFSEIKEILPSAMINTV
                     PAWDIPSGVTVAQLGALVEPVAEKQAFLPRYLKRVEAEEKWLETHTPGDESYVEKI"
     gene            complement(4495..5475)
                     /locus_tag="IXR40_001576"
     CDS             complement(4495..5475)
                     /locus_tag="IXR40_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAQ4361430.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPADGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            complement(5499..6983)
                     /gene="galT"
                     /locus_tag="IXR40_001577"
     CDS             complement(5499..6983)
                     /gene="galT"
                     /locus_tag="IXR40_001577"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HAQ4361431.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLEDYPQVIAGVVKWPMSVIRLQSTEKNLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            complement(6995..7984)
                     /gene="galE"
                     /locus_tag="IXR40_001578"
     CDS             complement(6995..7984)
                     /gene="galE"
                     /locus_tag="IXR40_001578"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010767298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HAQ4361432.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREILGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            8232..8399
                     /locus_tag="IXR40_001579"
     CDS             8232..8399
                     /locus_tag="IXR40_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HAQ4361433.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            complement(8461..10272)
                     /locus_tag="IXR40_001580"
     CDS             complement(8461..10272)
                     /locus_tag="IXR40_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HAQ4361434.1"
                     /translation="MKIGIIGAGPRGLSVAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNVLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSRGGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGAMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLETPLAYQNEPFSEASRIFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPIIRTKELAALIDAGIFHLIEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(10269..10634)
                     /locus_tag="IXR40_001581"
     CDS             complement(10269..10634)
                     /locus_tag="IXR40_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 family protein"
                     /protein_id="HAQ4361435.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            complement(10797..11192)
                     /locus_tag="IXR40_001582"
     CDS             complement(10797..11192)
                     /locus_tag="IXR40_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HAQ4361436.1"
                     /translation="MVLWVINIILLLIVLAIILWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            complement(11210..12172)
                     /locus_tag="IXR40_001583"
     CDS             complement(11210..12172)
                     /locus_tag="IXR40_001583"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HAQ4361437.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRFLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACGNLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            complement(12172..12384)
                     /locus_tag="IXR40_001584"
     CDS             complement(12172..12384)
                     /locus_tag="IXR40_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HAQ4361438.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            complement(12405..13103)
                     /locus_tag="IXR40_001585"
     CDS             complement(12405..13103)
                     /locus_tag="IXR40_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HAQ4361439.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            complement(13123..13665)
                     /locus_tag="IXR40_001586"
     CDS             complement(13123..13665)
                     /locus_tag="IXR40_001586"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HAQ4361440.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            complement(13797..14801)
                     /locus_tag="IXR40_001587"
     CDS             complement(13797..14801)
                     /locus_tag="IXR40_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HAQ4361441.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIVLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILPSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            complement(14798..15787)
                     /locus_tag="IXR40_001588"
     CDS             complement(14798..15787)
                     /locus_tag="IXR40_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HAQ4361442.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVEKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            complement(15784..16590)
                     /locus_tag="IXR40_001589"
     CDS             complement(15784..16590)
                     /locus_tag="IXR40_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4361443.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKIALLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            16756..17712
                     /locus_tag="IXR40_001590"
     CDS             16756..17712
                     /locus_tag="IXR40_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAQ4361444.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            complement(17789..18307)
                     /locus_tag="IXR40_001591"
     CDS             complement(17789..18307)
                     /locus_tag="IXR40_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAQ4361445.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(18395..18544)
                     /gene="rpmG"
                     /locus_tag="IXR40_001592"
     CDS             complement(18395..18544)
                     /gene="rpmG"
                     /locus_tag="IXR40_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HAQ4361446.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            18772..19218
                     /locus_tag="IXR40_001593"
     CDS             18772..19218
                     /locus_tag="IXR40_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HAQ4361447.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            complement(19413..21308)
                     /gene="asnB"
                     /locus_tag="IXR40_001594"
     CDS             complement(19413..21308)
                     /gene="asnB"
                     /locus_tag="IXR40_001594"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HAQ4361448.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKIDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEEWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
BASE COUNT         6505 a         4563 c         3710 g         6803 t
ORIGIN      
        1 gaaaaaattt ttttgaataa attaaaaaaa taaattatat tatcgttgtt agcgtttact
       61 atatgtatta ttgttgtttt ttatacacaa atcattcgct tcaaaacaaa ttattcaata
      121 ccattgtata ttttttacat aataacaaat tatatttgta aagtattaaa acttgtttct
      181 aatgttggta tgttaaaact ttacaaattc tttaaaaaaa gtgacaataa atatagtgaa
      241 caataaggag aggacttttt aatgcgtgtt aataaaatcg attttcactt ttcaaaactc
      301 agatatcaac ctgattttga acatttctcg gatgaagagt tccaacagat caaggaacat
      361 actgttcttc gttcttataa aaaaggacag atccttttcg acgatggtga tcccagacaa
      421 cggttgtata tcttgaccaa aggactcgtt cgtttagaac gttatgatga aagtgcaact
      481 tattactact atgactatgt gaatacaaat aacctttttc ctatgtcagg aatgtttgga
      541 gaagagacct acacttatac agctcaagcg atgactgata ttgaaacatt ctaccttcct
      601 gtttcctact atgaaaaatt agcacgaaaa aatcccgaac agttgatcta tatgatacaa
      661 aaaatttcta aagtagttga aatacatgaa ttgcgtatcc aaatcggatt gacctctagc
      721 gcctttgacc gggtaaaaca aaatttattc attttgaaag aagaattggg cgtaccaaca
      781 aaagatggtc atatcaccat tccttatccg atcaccttaa aagaattagc agtgaatagc
      841 ggcacgacac gtgaaactgc tggacaagta atcaaacaac tacgtgattc cgggctgtta
      901 gattatgaca aaaagcgttt tactttctgt aagacagcta ctactccagc tatgagagaa
      961 taacgcgaac aaaaataagc agtgaccctg ataaatatca gggtcactgc ttattttcct
     1021 ccctaaaact tctgaaagat ccggcagttt tagatcactg gacaagactc aaagattttc
     1081 tatgtgtgtt tcagttatgt aatattcact gtttgcaaaa aatactgtta gattaactag
     1141 atgaagcgtc ttgtcctcat ccgatctaga ttattcgata ttcctcgaca ataaacgatt
     1201 actcagtgag ggcaatcaga ggaacggata atgataaata agctgtaaaa aatagcaaaa
     1261 taacaataat gattaaaagt atgtaaaaaa tagggctttg acaaaaacgt gtcacagccc
     1321 tatttcgatt aaacggtgtg tacctgtcaa ctcttcggtc acaagtcata atgttcataa
     1381 acatgaggag ctgttttttg aaattgttcc ttgtgaatca gagttaaacg acaggcttac
     1441 gaactcttga ttaaacggcg ttcaaaagct tgcatacgcg gtaataagaa cagccaggtc
     1501 aaaaacatga gaagccgttt ttcctgggct gttcttatta cttgatgcag ggcagctttt
     1561 tcacaacctc tttattcaga taaaaccaag cttggatcag cattcaactg atagctagca
     1621 aaatttcttt tttgcatttc cacatgtgct gctgctccaa tcattgcagc attatctcca
     1681 caaagtcgaa gagggggaat cactagttct acctcaggga gtttagctgc caaagcatcc
     1741 tgcaatcctt cacgcaaccc ttgattggcc gctacacctc cagctataat cagttgcttg
     1801 actggataat tttgacaagc tcgaagtgtt ttagtaatca atacatcgat cacacttgct
     1861 tgaaagctag ctgctaaatc atttttgtct agatcttctc cacgctgttg tgcattatgc
     1921 accaaattga taaatgcact ttttaatccg ctaaaactga aatcataatt atcttcatgg
     1981 atcatcgctc gcggaaaatg gtaattatct tttccctgat gagctagctg atcgatttct
     2041 tttccgcttg ggtaagaaag acctaatact cttccaactt tgtcataagc ttctcctgct
     2101 gcgtcatctc ttgtctcccc aatgatttca tatgatccat cttcttgcat atagactaat
     2161 tctgtatgtc ctccgctaac aagaagtgcc atcaatggaa actggaatgg tttaaccaga
     2221 cgggctgcat agatatgccc tgccatatgg tttacaggaa taagcggcaa ttggtgtgcc
     2281 caagcaaaag ccttagctgc agaaatacca atcagcaacg agccgacaag tcctggtcca
     2341 taagtgacag cgactgccga taaatcttct gccgacacac cagcttctac cagtgcatct
     2401 tccaagcata aggtgatttg ttctacgtga tggcggctag ctacttcagg tactacgcca
     2461 ccaaaacgtt tatgactgtt tatttgagaa gcaacgatgt tagataagat ctctgttcca
     2521 tttctaacga ccgctacact cgtttcatca caacttgatt caatcgccag aatcaattct
     2581 tcattcattt catcgtctcc gtttttaact ttctgctcat aatgatcgca tcttccgtcg
     2641 gattgcgata atatgatttc cgtttaccta atatacgaaa cttttctgat tcataaagtt
     2701 ttcttgctgc ttcattagat agacgtactt ctaaaaaaac atgcagcgaa tcttttattt
     2761 gttccgtaat cagtaattgt aacaaatgcc gtgcatgccc ttttccttgt tctgaaactg
     2821 caacagcaat atttgtgatc tcgacttcat ctattacttt cgagtatcca ataaagccac
     2881 agatctggtt atcttcagct aaaagcagat aatcagagtg aggctgttgg atgtctgcca
     2941 aaaactgcat tttcgtccaa ggtgaaccat gtggataagc attttcgcta atcatccata
     3001 cgcattctgc caagtacgct tcatcaaaat ctttttttct gcaaatcaac taatctcact
     3061 cattttctaa aagttttatc atatccaacg catcttcttt tgtttcagtg taatatcttt
     3121 ttttgatcgt tgttgcttga aaccccaatt tccgataaag tctttgtgca tcttgattac
     3181 tcatacgcac ttctaatgac atcgtctcac agcgattcat tatagcaaag ttctcgattt
     3241 cgtcaataag cagcgaaccg attcgtttac gctgatatgc cggtcgaacg gcaatattcg
     3301 tgatatggca atctaaaccg aacgctcttg aaccgataaa accaatcatt cttccattat
     3361 caaagatacc tagatataga tgaggaagcg gtgacttcaa ttctgatata aaggcacttt
     3421 ttgtccatgg caattcgcca ttatagactt ctcgttcgac atccagcagc tctttgatat
     3481 cttctgtagt caattctctt agtacgtaac gacgatcgat ttgttcgact gttttttctg
     3541 tataaatcat tttatcttga aaaaagcttc tggcatacgc tctaaatttt ttcaacataa
     3601 ctttcgtctc caggtgtgtg cgtctccaac catttttctt ctgcttctac tcgttttaaa
     3661 tagcgaggaa gaaaagcttg tttctctgca actggttcaa ctaaagcacc taattgagcc
     3721 acagttacac cacttggaat atcccatgct ggaactgtat taatcatcgc actaggcaat
     3781 atttccttta tttcagagaa gaatttgtga caatcactcc cgacgaaata aatagcttca
     3841 ttcagctttt gtagttgtgt gaacaaatca gaagcagaaa tatgtacatc ttcaagtaca
     3901 gtttctaatc tattttcttt ccagcggtat gccccagcgt atacattttt tcttcgagca
     3961 tcaaacatgg gcacaataat attatccaca ccgatgcaat tagccgcgat ggttttcaga
     4021 ctagatactc ctactagctc tttatctaat gtataagcaa tcgtttttgc tgtcgttaca
     4081 cctatacgaa gccctgtata agaaccggga ccatcagaaa ccgcgattcg gtcaatgtct
     4141 tttggactta tttgaagatc tgcaaacaat tggtcgattg caggcatcag tgttacactg
     4201 tggttgcgtt tgatatttgt ttgtatttgt ccaagaattt gttcgtcttc taccacaccg
     4261 atcgccaaag tttggtttgc agtatctatt cctaatgtaa tcatatattt gatcctttct
     4321 gctatgacat tctcgccttc cattgtagca tactttttta ttctgaggat gaaaatacca
     4381 aaggcaaaac tagtacaata atacatgatt atctgctggc gggcaaattt tgccccttcc
     4441 tgaaacacaa aaaagctgcg gtatcactcc attttcccac agcttttcca tcttttattt
     4501 cgttgattct cgaataatca actctgtttc cacaataatc tttcttgaaa ccggtgcttt
     4561 ggaattactt aattgaagaa tcgtctccac tgctagctct cccatccatt cggtataaac
     4621 ttttacagta gaaagcgagg gcgttacata tttcgctaca ctgacatcat tgaagcccat
     4681 cacagaaata tcttctggta ccactaaacc tttttcttga atcgctttca gtgcgccaat
     4741 cgctaatgca tcattagctg caaaaagcgc atcaggaaca tgcggattcg tttttaaata
     4801 ttgcttcact gcttgatatc ctgactcgac agaaaaatct gcttcgataa ttggaccttc
     4861 gtcgtagcct ttttctgcca aaacttgttg aaatgccata attctgggat cttttagccg
     4921 ctgatggttt ttcttcgtat attctgttcc agcaagcata gcgatatgtt gcgctttatg
     4981 ggagacaaag tgttcaatga ctttttgaac acttgactta aagtcgacaa ctagagagtc
     5041 gattccttga gaagtgccgt cagaatctac caaaagcaag gcattttggg atcctttcat
     5101 ttctaataac tgagcttcgt cgaattttcc tagtgcgatc gttccatctg ccggaagatc
     5161 actaatggaa tcccacgttt ctttcaataa agtaacgttt gcttcttctg cctttttttc
     5221 gattcctagg cgaatagata aataataaag atcttcaagc tcttccgtat cgtcgtacca
     5281 ctggatcagg cgaagcgttt gcttagtatt tgctgcattt ttacgatgtt tcgtataatt
     5341 taagcgttct gctgcttcaa aaattttttg ctttgtggct aagccaacgg aaagatcagg
     5401 atcatagttg agaactcttg aaacagtagc aggagaaact cctgccaact gcgcaatgtc
     5461 tttaattgtt gccatttgtc tctcctcctt ttttacgttt ataaaatcgc agtaaatcgt
     5521 tcaaacgctg cctgtccttt ttcatctcgc ttgaatactc cagcgtcttc cagtacacgt
     5581 gcaaaaacct gacctacaga tttttgtacg acatcggtga ccgtatcttt cgtcaaatca
     5641 ggatgttctt tttttaattg ttctgcccac ggacgatgat attcagccat ctggttttct
     5701 tctcctaata agaaatgctc tacttctact agttctggtt tcaaacgagg tggtaaaaca
     5761 gcaagcccca ttacttcgat caacccaatg ttctcctttt tgatatgttg gacatcttta
     5821 tgtggatgaa aaatcccatc aggatgttct tctgaaacat tgttgtctcg aaggacaagg
     5881 tccaactcaa agtaattgtc ccttcttcgt gcaattggcg taatcgtatg gtgtggtgta
     5941 ccatctgctg aaaaagctct gatagatact gtttcatccg aatatgcttt ccatttttcc
     6001 aatactgagt tagctgcttc aataagcaag tttttctctg ttgattgcaa acggatcaca
     6061 gacatcggcc atttcacgac tcctgcgatg acttgcggat aatcttctag tttgataagt
     6121 ttttctatcg gtgcttttgc cataggaaat tcatgacgtc ctgcctgata atgatcatga
     6181 gaaagaatcg atcctccaac aattggtaag tcagcattcg aaccaacaaa gtaatgaggc
     6241 aagacttcag taatccgaag cagtctagca aatgtttcct ttgtgatttt catcgggcgg
     6301 tgttgttctg ataaaatgat cgaatgttca ttgtaataag cataagggga atattggaat
     6361 ccccagcttt caccgtctag attcattcga ataatccggt gattggtgcg ggctggatag
     6421 ttcaagcgac ctctatatcc ttcgttttcc atgcaaagca tgcaggtagg atagtctact
     6481 tttaccgcct cgcgttctgc tgcgatttgt tttggatctt tttctggctt agataaattg
     6541 attgtgattt ccagttcacc atactccgac tctgccggaa atttgatgtt ttttgcgatg
     6601 gctcttgttt tgatgtagtc atttttctta cttaaattaa agaaatactc agttgcttcc
     6661 tctgggcttt tcgaatagtg ctgtgcaaag aatgcattga cgactgaagg tggcggtgtg
     6721 agaaaatcca ttaattgcgc ttcaaaaatc tcttgttctg ctggcaattc tgaaagaaca
     6781 ccattttctc ttgccttagc gacaagctga tccaataagt ctacagattc ttccttaact
     6841 ggtcttactt caatgctttc tagagcatct tctcctacca tccctaaaag acgattctgt
     6901 aaatataagc ggtccatttc catccatccg ccagcttcga tcgcaagtgt ggcaaaatca
     6961 caaatcgttt gactgattga catatctcat tcccctattc ttcataacca tttggatggc
     7021 tgacatgcca atcccatgct gttttgataa tcgctttgat atctgtgtat tcaggtttcc
     7081 agcccagaat ctctctcgct ttttcacttg aagcgactaa tcggctagga tctccagctc
     7141 ttcttggtgc tatttctgct ggaatttctt ttcctgtcac ttctctagct gcttctagca
     7201 tttccttgac tgagtatcct ttgctgctgc ctaaattgaa gaagttgctt tcatttcctt
     7261 ctttcaagta ttccaaagct aaaatatgtg cagcaatcaa atcttctact tgaacataat
     7321 ctctgataca tgttccatct ggtgtatcat aatcgtctcc ataaacagcc aaggcttttc
     7381 tttgaccaag agctacttgt aaaatgattg ggacaagatg cgtttctggt gtatgatctt
     7441 ctccgataga tgcatctgct tttgctccgg ctacattgaa gtagcgcaaa gcgacatagc
     7501 gcatgccata tgcttggtca caccacttca tcattttttc catcatcaat ttactttcac
     7561 catacggatt tttaggatta gctggtgtat cttctgtgat tggagactct ttcggctctc
     7621 cataagttgc tgcagtagaa gagaatacga ttttattcac gttgaactcg tgcatgactt
     7681 caagtaagat ttgcataccg tatacgttgt tgttgaaata catcaatggt ttttcgacag
     7741 attctcctac taaagagctt gcagcaaaat ggattactcc ttcaatcggt tccttttcaa
     7801 atacggaacg tagaaattct ttatcccgga tgtctccttc ataaaaatga gcatctggat
     7861 gtactgcttg tttgtgacct gtgagcaaat tatctaccac agctacttga tacccctttt
     7921 gaactagctg gtctacagcg tgcgaaccga tataaccggc tccgcctagt actaaaattg
     7981 tcataaaaaa cactcctttg attagtaaaa ttgtgtttgt tgattctata taatttaaaa
     8041 aacgaagttt acttttatgg tgaaaacaaa caaagtaaaa tttcgtaaat tcatatggta
     8101 aatttataat aaaacattta gtaaacattt tcaagggttt tttgcaaagg tttacaaaca
     8161 aacgtaaaac tagccttttt ttctcttttg ttccataata gatataacaa ataataaatg
     8221 aggtggattc aatgaaaaaa tttgtatctg gaatattagt aggaagtctg gcaacagccg
     8281 ctgccgttgc tggtttggtt gcttctgtga aaaaaacagt gatcgatcca attgacgaaa
     8341 aagaagcaat gatcgaagaa aaccgtaaaa aagcaatgcg taaacgcgtt tctcgttaat
     8401 aattatttaa aaatacgcat gaagactttc taaaaaacag ataagtcatc atgcgtattt
     8461 ttatttgtca gtcaatataa gttgtgctat tttatctgcc tgtctcagat tccatggatc
     8521 tgtataaggt ctagctactg ctgcagttag ccaatccaca ccttcaacag gtattccata
     8581 gcaataaaag tcagactgga tttcccctga agcatcaatc acgcgattcg tacctcgctc
     8641 aacatctata gcttctgaat gataacttcc tgtattatct gaaaatgaaa aagggcgaac
     8701 aagtttgttt tccttcaaat tttttatgac aggattactt gaacgagaaa agcttgtttg
     8761 tggcaatcga gcttcaatca aatagcgact gctgatttct ttatcttgta gagaaataac
     8821 atagcggttg tgcttttgct gaatatcaaa tggcggttcg atcaaatgaa aaatacccgc
     8881 atctatcagt gctgctaatt ctttcgtccg aatgattggc ggaccgatcg ttaaaaagct
     8941 atttagatga gtaaaccatc cccatagtat ttctttgtat tccttagcag aaaaaacgtg
     9001 ccattcaata gcctgccgga ttggatcacg ccagtctttt aatgcatcaa atgttgaagc
     9061 aaatgctcct gtgcaattgc ctttttccgc ttcttttatc tgcccttcaa taaatattcg
     9121 gctagcttct gaaaagggct cattctgata ggcaagagga gtttctaaat acgaccaatc
     9181 ccatctataa gggattagtg ctggatgctt tccgagacac tcctctgaag agagggagag
     9241 aaaatcatgc tcaaaatttt tctttggaat cggcaagtga tattcttcga tgattttctt
     9301 gtaataaaac aactcaacgt cttttttcag atagtcaaaa aatgtttcgc cagtcaaaaa
     9361 tcccgactga tgccattgct ccaggttttc ttttgttagt aaccgtggcc atgccattgc
     9421 tccgccttgc ttttgatttc ttcctcgagg gtaataaggg agcccccttc ttgatccact
     9481 gtatacaatc ggttccttgc ctgatggatg atagaccagt tttccctttt cgttctcgaa
     9541 gcgccctcct cttgatactg taaacaatcc gacataatca aaaaaactta agcctagacc
     9601 tcttaaaaag acattttctt taggcggtat cttcgaaaga tctacatctg caggattaga
     9661 aggaagctga tacagtaaaa catttttctt tgcgtagtct acccacactc tttcttcttc
     9721 tgtctcatca ttttcccagt gaccgcttgc taaaacaagc tgatcgatag aatagctttg
     9781 ctgatctgtc tgtaaaagat aaccatcttt tcttttgctt acttttttta ctaaagaata
     9841 aacaaactga atagaagctg gaaattcttc ttgcaacttt gagaaaaacc agcgttgata
     9901 gagtccgtat aaacatcgag tagattgctg atctttttcc agacgattga tttcttctat
     9961 aattagttgc ttatttttgg ttaccgtctg ttcgatataa tctgtagcag gtcctttact
    10021 ccattgaaac aagttgggtc cctgtgttac caatcctcca ctggacaatg tttcatctgt
    10081 aaaaagcgtc acttgttgag aaacagaatt cattaataac tccggtggct gattcaaccg
    10141 ccaaactcga cctccaggac cattgggatc gaaaagaaaa agttcaagag aatgtctgtc
    10201 ctgattatta tggagaatcc tttctgctac acttaatcct ctaggtccgg caccaatgat
    10261 ccctattttc atttgcatgc ctccatttcg ataaattttt tcaataaaac agcatggttc
    10321 tgatgttcat tttttgcacc ataaacaaaa gtaatgactg gatgttcttt cataagttga
    10381 ctgagtttaa aaatagcttg cttcttttct tcttcgaaaa tcaattcttg ctggtatttc
    10441 tttgcaaatg aagcaaatcg ttctggtaca tggtcaaaag ttttgcgtgc ttcattacta
    10501 ggtgcaattt ctttcaacca cagatctaac tgcgcttttt cttttgaaat tcctcgtggc
    10561 cagaatctat ccacgagtat tctatagcca tcctcttttt cagcatcaag gtaaacacgt
    10621 tttaatttga tcatagttgt ttccttcttt ctaccttttc gcttagctta tatatgtaga
    10681 taatagcaca aaataaaaaa aatgaacggc acaactatcc attgcgccgt tcatgtgatc
    10741 ttggtcaaaa tctaatgatt gattcggttt ttaaagctgt catacaatca tctgttttat
    10801 acttttttac ttttgatttt tccagaccat ccgtcatatc cacccttaag taaataaatc
    10861 tcttgataac ctgctttacg taatttattt gctgtacgga tgctcaaact tttcttttga
    10921 tcgtaaatat agacaggctg gtcttttcga atagatccta atgaatcttt caaaacagtg
    10981 taagggatgt ttcttgcacc taaaatatgc ccagcatcaa acacatcttt ttcgcgaaca
    11041 tcgattactt gtgcttttct cattccttct cgaaattctt cttctgtcaa agtcgttgct
    11101 gaacgtttgg ccattactcg tagatagact tcccaaagga tgattgcaag cacaatcaat
    11161 agcaaaatga tattaattac ccataaaacc atgtaatgcc tccgtttttt taagcaaatt
    11221 tcaaggctaa tgaggcagca ccaatgacac cagcttcatt accaagctct gctaatttga
    11281 tttttgttga ttctcttact tgcgggaaag taaattcttt aaaatatttc tctacacggc
    11341 tacgtaaaaa ttctcctgct gccgatactc ctccacctaa cacgatactt gacggattta
    11401 atgtattccc caagtttccg caagctaaac ctaagtagaa gcatacgcga tcaacaacca
    11461 tcaatgcaaa cggatcgtct tcttgagcca tttcaaagat atctttactt gttacttctt
    11521 ctccgttgtc tagcattgct ttcagttttg aatcccctgc gtattcttct gccaagaaac
    11581 gacctaggcg taccacacct gtagcgctag atacagtttc taaacatccg cgtttaccgc
    11641 aagtacattc gaacccttca ggatccacag tgatatgtcc gatttctcct ccagctccgc
    11701 tcacgccgtg aatcaaattt ccgccagcaa cgatacctcc gccaacacct gttcctagag
    11761 taacgaatac aacgtctgga tcgttttctc cagcaccttt ccatcgttca cctaaagcag
    11821 caacattcgc gtcattatcg atagcgaatt tgattcctgt tcctgcctcg atcagttttt
    11881 tcacaaattg aacttctgtc cagtttaagt tatacgcacc aataaccgtt ccagcttcgc
    11941 tgtccacgct tcctggggta cccatgccga ttccgataaa gtcttcggct ttcatattat
    12001 ataaattcaa acgatgattg attgattcaa tgatttcagg aacgatatgc ttaccatcat
    12061 ccaaaatatt ggtatcgatg ctccattttt gctgaatctc tccttctggt gttaaaattg
    12121 caaattttgc tgttgttcca cctaaatcaa tcccaataat cttcttgtcc attacaaatt
    12181 tcctttcttt cggctttctt caattcggtg ctctcttttt aatatgcgcc acgctgtcat
    12241 gtatgtatca tgatcaatca aacggctatc atacagatta cgcaattcga tagtcattaa
    12301 ttcaatgtca tagatgcgtg cacccacata gataaagatg ccaaattttt tgaacagctg
    12361 ctgtacatca tataagctct ccatctttaa gcacttcctt catattatac aagtaaacca
    12421 tattttttta aacccagtaa aatacatatt acaaaaagaa atacaaaaac tagtgtagaa
    12481 agaatccttt ggtgtatcga atagcttgtc tgttgtttcg gtagacccaa aacattccct
    12541 aacactaatc cgccaattag cccaccgaca tgtccccaaa catctacaga ggtatccaga
    12601 agaccaaaaa caaatgtcaa cacaataaat aaaagaaaat gtctgactag ctgctggatc
    12661 gctgggttat gtttaaaatg aaaccctaag ataaacaacg caccgaacaa accgaatatc
    12721 gaagtacttg caccaccaga cagaacattc gcttcgttaa aagcaaagct tgctgtattt
    12781 cccattatcc cgctgaacat ataaatcaag aaaaaacgcc aatggccata gattgcctcg
    12841 atttgctgcc ccataaaata cagtatcagt gagttcatta cgaaatgcat cagtccaaaa
    12901 tggatgaaga ttggtgtcac taaacgccac cattcattga agtgaacaag ataaggacca
    12961 tacattccgg cataataagg gatctcaagt cgcggaaata attccatcat gaggaagacc
    13021 gctgtctgta tccctaaaaa agcataggtc cataacggtc gtcttaacca tgcacgcaat
    13081 tttatttgct gttgataatt catgaaaacc tcccatttca ttttagtcaa taaacaattg
    13141 ttggatcttc tgatcaaagc tctccggttg ccattgttca ttcaattgtt cacgaaaaac
    13201 aaggctacat gtttttttat gaaaattatt taaataccgg tcgtaataac caccgccaaa
    13261 accgattcga taaccggctc tattgtagat aatacctggt acaatgagga gatcgatcat
    13321 ctccggcaaa tagagcttct ctgattgtgg ctcaagaaca ccaaaactcg aacgtacaag
    13381 aacggactgt tcatccattt cataaaacgc catctgacgt ttcggcaaag ttttaggtac
    13441 aactattttc ttttgttctt tttctgctcg ttggataacc ggctgtgtat ccagttcaaa
    13501 ttcattcgat aaagtcgtcc ctatcacttt tgctgacttc cagtactcgc tggcgaatag
    13561 ctgtttatag attcgctgtt ctttttcctt tttcttgcca cttttggcca gatttttcag
    13621 cttttcgatt cctttccggc gtaatcttac tttcaattgg tccaaaaact cacccttcct
    13681 tctctcataa aatggtatag gaaaaaaaga aaaatagcaa tcgaactttc aaataaatgc
    13741 ataaatagaa taaaaagaag acctagaaat gattggcctt ccttttttaa tgaatttcaa
    13801 ctgttcagcg cgtgtttttg tctgataaaa agtgcataca gaaaatatgg cgcaccaaaa
    13861 agggcaatca aaattcctgt aggtacttcc ccacttggta gaatcactct agcaaccata
    13921 tctgcactaa gcagaaaaat ggaaccgaac aaaccgctca gaacaaaggt ccagttattt
    13981 tctttacgta cgactagctt cgcagcatga ggagctagta gtcctacaaa agataaacta
    14041 cctgtcaccg ctacactacc gcttgccaaa gcaacagcta acaacaaaag gattttttga
    14101 cttttagcca cgttaaggcc taatccttgc gcgcgttctt gaccaaatga tagcaataca
    14161 atcctctgtg cataaagtcc tcctagcgga attaagataa ccgcccatgg aagcaatgcc
    14221 caaacataag gccagctcgc accccagatt gatcccgcta accatgcatt cacaaatcca
    14281 taattttcct tagataattg gatcgtgcat agcaatgtta atgcagaaag gccggcatta
    14341 acggcaatac cggacaataa gattcgattc atacccaaaa agccatttcg atcataggcc
    14401 gcaagataga cacagcaagc agctaaaaca ccacctagaa aggctacaac tagcaataga
    14461 aacggcagcg aatagtgcga aaagaaacct aaataaagca tcactaaaaa tcctgctccg
    14521 gcattaatgc ccaatatact agaatctgcc aattcatttc ttgttactcc ttgcaagata
    14581 taaccagaaa cgccaagaca agctcctgct aataaactga tcagtaatcg aggaactcga
    14641 aattctctaa caatcagcgc caaagaagat gattctttcc ctatgaacgt ggcaaaaagc
    14701 tgatccaggt aaataaaagg cgtaccaatc attaaactac ctatagacag gatgacaagt
    14761 acaaaaagca agaaatagaa cgtccaatat atttttttca ccgttgttcc ctccttactt
    14821 gtatcagtaa aaacggaacg ccaatcaatg caatgactaa tccaaaaggt gtttcaaaag
    14881 ggggattgat catcctcgct gtaaaatccg ccaacataac caatccaccg ccaactaaaa
    14941 aagagacagg tagaacataa cgatagtccg ttccaaccat tccgcgaaca actggcggaa
    15001 ccaacagccc aataaatgaa acaggtccga ctaacgaaac ggcaatggct gctaacactg
    15061 caactagaca gaaaacaatc aaccgcgttc gtttaggatg acttccaaga gctaatgcat
    15121 gtgtttcact caaatgaatc aaagatattg cttttcctaa tgaaaaagaa accaaaacag
    15181 caagtatata taaaggaaac aatactgcta attgtttcca tgtgatattg gcagctccgc
    15241 ctacaaacca aaaagcaaga tcctgctgca gattaaagaa ttgggtaagt gcttggctga
    15301 tagcagtaaa aaaagaacta atagctacgc cagctaaaat cagctgtaaa ggattcatgc
    15361 ccattttcga aaactgcaaa aaaccaaata cgagcaaagt tacagcaaaa gaacctgcca
    15421 atgacattag aaacacagaa aaatcagaag ctttaggcca aaaagcaaaa ctaagggcca
    15481 ttgccaacga agcacccgcg ttgattccta gtaagcctga atctgctaaa ggatttcttg
    15541 tcactccttg catcaatgca ccgctcaatg caaaacaact ccctacaaga aatgctcccg
    15601 ccacacgagg caaacgaata tttcgtatga tttggtgact ttgttttgat ctatcaaaat
    15661 caaacaacgc ctgccaaaaa tctgcttttt ccacagtcgc tgcgccattt gaaagagcaa
    15721 caaaaaaaat aatcaaaaga acaaaacaga ccaaaagcag gagtctattt ttcttcatag
    15781 tcctcataat tgatcctcct gctcttttgg caacaaatca taggttagaa aaactggttt
    15841 atttgttctt ggaagcgtga caatcgttgc atcaatctca aatatttttt tcatacactc
    15901 ttttgtgatc acttcttcag gtgtaccttc tgtgatcaac ttaccgtttt tcattgctaa
    15961 taaataatct gaaaaacgtg aagcatgatt aatgtcatga atcgacatca agatcgttgt
    16021 ttgtttcatt tgattgattt cagtcaataa ctgtaggatc tctaattggt gtgccggatc
    16081 taaaaatgtt gtcggttcat ccaagatcaa gatatctgtt tcctgagcaa gcgccatagc
    16141 gatccagaca cgctgggttt gtccaccaga cagcgttgcg atatcccgca tacgaaatcc
    16201 agctagacct gtagcatcca acgcccactc aattgcttca tgatcttgcg tgtccatgcc
    16261 actgaacagt ttttgataag ggtatcgtcc gtaagatact acttcttcta ctgtcatacc
    16321 tgtagggtgt tcactagttt gtgctaataa tgcaattttt tttgcaagtt cttttgaact
    16381 gtatgtagag atatcagagt tattgacaat gatctttcct gatttcacag gtagtatacg
    16441 ggtaaaactt ttcaataaag tagattttcc acttccattt ggcccaatca aactagtgat
    16501 tttcccttca ggaatcgtaa cagacatgtt ttcaatgatt tttttgtttt cgtagccggc
    16561 tgcaatgtca gctgctctta atctcgtcat ttcacccatc ctttcgctga aaatcattct
    16621 caattatgac gctgtttcaa catttcgtca agcgctactt tcatatctat agccaaatga
    16681 agcggttgac agcgttcgaa atatcaggaa taataaccaa tgagaaagat tctcaattat
    16741 gttaggagga aagaaatgaa attaaaaaca aaagtattca cattatctag catattgctg
    16801 ctggctggag tactgagcgc ttgctccccc tcttcagata aagaaacagc tacaactgcc
    16861 aattcgacga cttcatccaa tagtactcat acagtcacag atacacttgg acataaagta
    16921 gagattccaa acgcgcccaa acggatcatc ggcagttact tagaagacta tctgattgca
    16981 ctaggggaaa aacctatcgc ccagtggact gttggcagtg gttccattca agattatctg
    17041 caagatgatt taaaggatgt cccaacgatt tcttatgacc ttccttatga gaaagtgtta
    17101 agctttgagc ctgatttgct gttgatttct tcttccgcta ctgtcgaagg cgggaaatac
    17161 gaacaatata gcaaaatcgc gccaacttat gttgtaaaaa acggaacaga tgtcacatgg
    17221 gaagaacaac taaaagatgt cggcaaagct ttggcaaaag aaaaagaggc agaaaaaatc
    17281 atttccgatt atcaaaaatc catcaagaaa actcgagaag aactagcaga taaaatcgag
    17341 aacaagacag ctgcagtgtt gtgggtgacc aacaactcag cctttatggt cagcaaaaat
    17401 cggtcaagtg gaagaatcgt atacgacgat ctggaatttg gtgttcctga tctagtggaa
    17461 gaggtctcca aaaaagccac ttctgactgg tctgctgttt cctctgaaaa gctagctgaa
    17521 ttagatgctg actacatcat ccttgtgaac agtgacaaag atgctgccat gttcaatgaa
    17581 ccaagctgga agaatctaaa agcagtgaca gacaatcatg tactgcaatt cggacctgaa
    17641 tctagttggc tatataacgg acctattgcc agtcaggaaa tggtcaatga tatcaaagaa
    17701 aaactaaatt gattttaact aaaaaaagca tcttcacgat tagtcgtgag atgctttttt
    17761 tcttattaac aaactagacg catagatttt attcttcttt tgaagcaacc ctatttttta
    17821 ctctttccca tttttgaaaa cgatgggcat atagattttc ttgatccgtt atcccctcat
    17881 actcctctat aagggcgaag tctgaaaaat caatattccc aatatacgta tcgccttcaa
    17941 acgtgctatc gatcaatgtt cgccagatcc gaccagtgta aggaagaagt tcttgaaaaa
    18001 tccgactacc acccgaaaca tagatatctt ctgagatcgt ttgactatac gacaaaagtt
    18061 catcgatcga atgcattact tccgcatttt ctttcgtgcg aaaatttggt tgcgttgtca
    18121 acacgatgat atggcgataa ggaagtgaaa gatcccccat tccttcatag gtctttcttc
    18181 ccatcactaa aattcgatcc attgtatgtt cgcgaaagaa acgcatatca tttggcaatc
    18241 gccatggtaa caaaccattt ttgccgatca gaccattttt atcttgtgcc cacatggaaa
    18301 taaacatatt atccgctcct tatgatttta gatgttttga gataaaaaaa gtctcaattc
    18361 tttgaccagc aaggaattga gaactttaaa aacattattt tgtttcacgg tgcaaagtaa
    18421 ctttgcgttc gcgtgggcaa tatttttgtt tttccaaacg atcaggattg ttacgtttgt
    18481 ttttgcttgt tagatagtta cgttctttac aagaagtaca ctctaaagtg atgtttacgc
    18541 gcatgttttt ccctcccatt tttacaagaa tcctctaaga tgactctcag acttgattat
    18601 cttaccatga ttttttctag attgctagtg tttttcacga ttttgttaag taaaactact
    18661 tgacgataaa tacaacggtt ttacttctca aacaaaatct ttttcttttt gtataaatac
    18721 ccttacactt gtttatatag attatgtttt ttaataaagg gggatactaa tatgccatgg
    18781 aacatgaagg actttcctgc atcaatgaaa aacttagata aattgacaag aaaaaaagca
    18841 atcgacatcg caaatgcatt attagatgaa gggtaccctg ataaccgtgc gatcccaatt
    18901 gccattgatc aagcaaaaaa atggtatgaa gatgctagtg aatcagaaaa acgaactttc
    18961 gaaaaagaaa aaaatccaag caagacggat gaacacgata cgaatcctcg tgctggaaaa
    19021 ctgcttgatt cagatgtgat cgtagaatat gaggaagaac aatggatcgt gaaatctaaa
    19081 ggggcaaaaa aggcaagcaa ccattttgat acaaaaaaag aagcaatcga aaaaggaaag
    19141 caagtagcac aaaacaaaga atcaactttg ttcatttata aaaaagatgg gacaaaagaa
    19201 aaagaaatcg attattgaac atatgtaaag gggttgtgac gaaaatcgtg tcacaacccc
    19261 cttatgttcg aaacaatggt gttcctctgc caactccgaa ccataagtca taatatctat
    19321 aaaacgggaa gagctgtttt ttgaaattgt ttcttatcac tcagtgttaa acggtaggag
    19381 aaaacctctt ttttattgat atttgatttt catcaaacag tcacatagtc gattgcttct
    19441 gcttgcggaa tcgtttcatc tacaaagtag actttatacc atgtcaagaa actgaagatt
    19501 gtccagattt ttctttgctc ttctttacgt ccttcgtgat ggtcatctag caacttcatg
    19561 attttttctt gatcaaaaaa ttcttttgca aaatctgctt cgaataatgc tttgacttgt
    19621 tcgtagccgt gttcttcttt caaccaagct ttgattggca cagggaatcc taatttcaca
    19681 cgattcgacc attcttccgg aagatgtttg ttcgcagctt gtctgaaaat atcttttgtg
    19741 ttgttttgat tcaataaaaa cttacttggt atttgttgag ccaatttcat gacttcgata
    19801 tccaataaag gtactcggac ttccaaagaa cttgccatag aaagtttatc tgcctttaac
    19861 aagatatctt ttggcatcca ttgatgaaga tcgacatatt gcatcttatt gacttcatct
    19921 ttgattcctt ctgttttctc gtaatgaaca gtcatgattt catccacaga tggtgctgtt
    19981 tgatattttg gtgttaacac ttctgatgct tctgattctt cgaacactcg agcatgaccg
    20041 ataaaatatt cttttgcagg agcaagtgat tcatataaat ggatccgtcc atggaagttt
    20101 ttcatttttc cgattttacg tcctaaatta tagcgtgttc cttttggtaa ttttttcaat
    20161 ccttgagcaa tcacacggat gaattttgaa ttcgtatgga atccatacgt ttggtatccc
    20221 gcaaacagtt catccgcccc ttctccagat tggactaccc gcacactttg tgaagcaaga
    20281 tttgctaaaa agtacaaagg tacgcaagaa ggatttgaat caggttcatc taagtgatac
    20341 tggatcaaag ggaatgcttt gaacgacatg tctccgtcga tcactgctgc tgtattatct
    20401 aagtccaata gttcggttag ttttctggct tcaatcgctt cattataggt tttatcatca
    20461 aacccgattg agaaagaatg atctggtttc aatacagagg ttacataact ggaatcaacc
    20521 ccgctggata agaaagaacc aacttctaca tcactgaccg tatgtgcttc aatagaagct
    20581 tgaacggttt cgtcgatttt ttcgatccat tcttgtcggg aatgcgtttc ttttgtttca
    20641 aaatctgcat cccaatattg ctgaatgtct atttttccat ctttatacgt ataataatgg
    20701 ccttcaggca aacgatagac atctttgaag aatgtttcgc cgtttaatgg agaatattgg
    20761 aaagtcatat aaggtttcaa cgcttctttg ttcaattctt tgttaaaatc aggatgaggc
    20821 agaaaacttt tgatttctga accaaacata aatgttccgt tcatttctgc ataataatat
    20881 ggtttgatcc caaagtggtc tcttgcaccg aataactcat tcttttcatt atcccaaata
    20941 gcaaaagcaa acattccgcg gatcttttgc aataattctg ttccccattc ttcgtaacca
    21001 tgcaaaagga cttctgtatc tgcatgtgtt tgaaaaacgt ggccagctgc aatcaattct
    21061 tctctcaaag gctggtaatt atagatttcg ccattaaaaa taatgatctt tgtccgatct
    21121 tcattgtaaa taggctgagt accgccctct aagtcaataa tacttaatct tctgaatcct
    21181 aaagcaacat gtttatcgat atattctcct gaactattag gtccacggtg aacgattcga
    21241 tccatcattg tattaataat tgtttttttg ttgtccttgt cgttaacaaa acctacaata
    21301 ccgcacattt aactttcaca tcctaatata aaattactgt ttatttcatt catatgcatc
    21361 ttatcataga ataaatagcg gacgaatatt ttctctctta caatttcgtc acgtgaaaac
    21421 aaaagatgaa agtttctgtt tttacagaaa ataaagtccc aatatctaat ttaccatgtt
    21481 ttcttttttg aggctacctt attctcttcg tgttaaaaaa atattagtgg atgctatttc
    21541 caaaaaaacc agcaaaaaaa gacacgacct aaagatcgtg t
//
LOCUS       DACGEU010000045        21211 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.045, whole genome shotgun sequence.
ACCESSION   DACGEU010000045 DACGEU010000000
VERSION     DACGEU010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21211)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21211)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21211
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.045"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(18..629)
                     /locus_tag="IXR40_001595"
     CDS             complement(18..629)
                     /locus_tag="IXR40_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAQ4361449.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     regulatory      complement(752..877)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(959..1675)
                     /locus_tag="IXR40_001596"
     CDS             complement(959..1675)
                     /locus_tag="IXR40_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HAQ4361450.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     gene            complement(1681..2250)
                     /gene="scpB"
                     /locus_tag="IXR40_001597"
     CDS             complement(1681..2250)
                     /gene="scpB"
                     /locus_tag="IXR40_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HAQ4361451.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            complement(2234..3031)
                     /locus_tag="IXR40_001598"
     CDS             complement(2234..3031)
                     /locus_tag="IXR40_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HAQ4361452.1"
                     /translation="MASKEKEERVNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDI
                     PIATITEQYMNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFVTDDEELWEE
                     DPREELVTQLLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKK
                     IDLIRAMQKILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESP
                     SKSEVVTTFMALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            complement(3001..3372)
                     /locus_tag="IXR40_001599"
     CDS             complement(3001..3372)
                     /locus_tag="IXR40_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HAQ4361453.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            complement(3391..4278)
                     /gene="xerD"
                     /locus_tag="IXR40_001600"
     CDS             complement(3391..4278)
                     /gene="xerD"
                     /locus_tag="IXR40_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HAQ4361454.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
     gene            complement(4374..4847)
                     /locus_tag="IXR40_001601"
     CDS             complement(4374..4847)
                     /locus_tag="IXR40_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HAQ4361455.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEKRNQSV"
     gene            complement(4952..5815)
                     /locus_tag="IXR40_001602"
     CDS             complement(4952..5815)
                     /locus_tag="IXR40_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HAQ4361456.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            complement(6011..8110)
                     /locus_tag="IXR40_001603"
     CDS             complement(6011..8110)
                     /locus_tag="IXR40_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HAQ4361457.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
     gene            complement(8330..9439)
                     /gene="rpoD"
                     /locus_tag="IXR40_001604"
     CDS             complement(8330..9439)
                     /gene="rpoD"
                     /locus_tag="IXR40_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HAQ4361458.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            complement(9463..11304)
                     /locus_tag="IXR40_001605"
     CDS             complement(9463..11304)
                     /locus_tag="IXR40_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HAQ4361459.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            complement(11486..13879)
                     /locus_tag="IXR40_001606"
     CDS             complement(11486..13879)
                     /locus_tag="IXR40_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAQ4361460.1"
                     /translation="MFLILEHARLKHVIIFESWRKMEKKKMNGLTQQEVVQKMASGQQ
                     NDYQEDASKSTKQIFSDNILTLFNFLNFGIGICLLFVGAYSNMAYLAIIVVNIVIGIY
                     QEIHARNLVRKLSIVSQSEVLVIRDGKEQSISTKELVLGDLVKIGAGEQIPADLQVIS
                     GRAEANEALLTGESDLIVKETGAELLSGSFLTSGSVMAEVIRVGADNYAVRLTSEAKT
                     HKAIRSELVDSIRKVSKFTSFVIIPLGIILFLEALFIRDASIKISVIASAAALLGMLP
                     KGLVLLISIALTTGVTKLAKKRILVQDMYSIETLAHVDTLCLDKTGTITEGKMSIQRV
                     EALHPLYEKAIPEIMGTYLAESSDNNITMRAMRDYFELSNRYDVTNKVAFSSDRKWGA
                     MEFPELGVVYVGAPERLVEEDRLPDSLKTAQANGYRVLMLGIAPNQQLNEEKPAFVEP
                     VALFEIDDPIRKNAQETLAYLHEEGVDLKVISGDNPFTVSNIARRAGLPNYDAYVDLS
                     QITEEMEVREAAHRYTVFGRVSPQQKKLLVNELKESGRTVAMTGDGVNDVLALREADC
                     SIAMAEGDGATRQIANLVLLDSDFTTLPEVLFEGRRVVNNVTKVSGIFFIKTIYSFIL
                     SIICAVTAIGFPFIPIQITLIDLAIEGYPSFFLSFEQDKRKITYRYLPTALINALPNA
                     LLVVVNIIAVYLLGKTFAWGNAETTTLMYYLLIGISCMAVVKACYPFNPLRIFLAVTT
                     IVGIYVAAMLFHGILEVNLGLGESVGYFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            complement(13986..14846)
                     /locus_tag="IXR40_001607"
     CDS             complement(13986..14846)
                     /locus_tag="IXR40_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HAQ4361461.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            complement(14905..15426)
                     /locus_tag="IXR40_001608"
     CDS             complement(14905..15426)
                     /locus_tag="IXR40_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="HAQ4361462.1"
                     /translation="MESYQIEITTAAKNYHMENYENLIKAIILTESKGKGTDLMQSSE
                     SLHGEAEIIDNPADSIDQGVKYLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHG
                     GENTVELAEAYSKDVLSPLLGNEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKM
                     NEKIIETYEKVFK"
     gene            15746..16465
                     /locus_tag="IXR40_001609"
     CDS             15746..16465
                     /locus_tag="IXR40_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAQ4361463.1"
                     /translation="MKKEKKYAKMPDGSEIYYEKSGQGFPLFLLHGNDGSGRFFSEQV
                     PVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEKIDQADFLGFSDGAN
                     LALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVWLLSLFRPSLRKNLL
                     VIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKTIPKASFVLVKEQGH
                     ELARKDPERFNREVLQFLSET"
     gene            16491..19082
                     /gene="mprF"
                     /locus_tag="IXR40_001610"
     CDS             16491..19082
                     /gene="mprF"
                     /locus_tag="IXR40_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HAQ4361464.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLISVLPMVGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDS
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(19270..20457)
                     /gene="tuf"
                     /locus_tag="IXR40_001611"
     CDS             complement(19270..20457)
                     /gene="tuf"
                     /locus_tag="IXR40_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HAQ4361465.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            20825..21181
                     /locus_tag="IXR40_001612"
     CDS             20825..21181
                     /locus_tag="IXR40_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAQ4361466.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
BASE COUNT         5802 a         4454 c         3718 g         7237 t
ORIGIN      
        1 cttgatcttt ttgatattta tttgactgct gtatgacgtt gttcgaactg atgttgtttt
       61 cgacttaacc atggaagaag ttgcgcatgc agcactaaaa agacagcact cacgatgaat
      121 cctttgatca agttgaaagg aacgatccca atcagtacat agtttgctaa agacatgccc
      181 agcatctgtg ttgcgttcag ccctaaaaac attaagtaaa gaggcgtaat aacgaaataa
      241 tttgcgatac tcataaaaat agttagagcg atggttcctg taatgacacc taaaaatttg
      301 tttcttcctt tatgctgttt ctttacacta aagaaataat aaatcgggaa tgtaaagatc
      361 gttgttgata agaaactagc agtgtctcct accaaattat ccggagaaaa acctgtagtc
      421 agcagatgta atactgaacg caagaacgct gttgcaactc cggccgctgg accgaataag
      481 aacatgctga tcaataccga gatatcacta aaatcgatct tcaaaaaact aaaagccggc
      541 atgatcggaa aagcaaaata ctgtaaaact aatgcgatcg cagcaaacat cgctactgca
      601 accattttct gtacacgggt gttcttcatt tgaaatcctc ctgttaggac tcctcttcag
      661 cgaacttttt gacgtttctc tccaaatgaa aaaactctat tttccaggga aaatagagtt
      721 agagttattt gatcaagcgt cgtcaaataa gctctatctt ctttatccag actatactgt
      781 cggtatcgga atttcaccga ttcagctatt tttttgcaaa ataggtcgtg gactataacc
      841 accggtcggg aatttcaccc tgcccctgaa gacgaacctt atataatttt tgtttacata
      901 ttcattatac atatctattc aaaaaacgca acatctaaca cttataaaaa gtaagtgttc
      961 attttgagtg gttcagcaaa ctgctgactt cttttttgtt cagttcacgg taatccccag
     1021 gacgtaggcc ttgtaaagtc agatctccgt atttttcacg ttttagtttt tgcacaggaa
     1081 gaccaactgc ttgaagcata tttttcactt gatgattacg tccttcgtgg atcgtcaatt
     1141 ccacgatact gtggtttgtc ttaggatcca ctgataaaat ttggaattta gctggagatg
     1201 tttttcgtcc ttcgatcttt attccttttg tcaaaggtgc aagcatcgat tttgtagcga
     1261 tcccttttac ctttgcaacg taaactttat ccacttcatg ttttggatgt gtcaggcgct
     1321 gagcaaaatc tccatcattt gtcagtagca agatccccga agtatcgtaa tccagtcgac
     1381 ctacaggata gatacgttct tttaccatcg gcaaaagatc cgtaacaact tttcttcctt
     1441 tgtcatctgc aacagcagaa ataactcctt taggtttgta caataaatag taaccgtatt
     1501 cttcttgata aattgggact tcatccactt ccacagtgtc atgtttccca acttttatcc
     1561 ctaattccct tacaacttgt ccgtttactt ttacacgtcc tgcaaggatg aattcttctg
     1621 cttttcgacg agaagtgatg ccagcgtggg caattacttt ctgcaatctc tccattacaa
     1681 ttattctcct ttattcattc catcaaagaa tagatctggt gacacgtctt cttcaagtga
     1741 aatttccatt tcttgtgtat caggcagttc ttctaatgat ttcaaaccaa aataatctaa
     1801 gaagtagcca gttgttccat ataatatcgg ccgacctggt ccttctactc tacctttttc
     1861 ttcaatcagt ttatgggcag ctagacgctg taccgctcct gaaacctgaa ctcctcgaat
     1921 ctgctcgatt tcagctcttg tgattggctg tttataagcg atgattgcta aggtttcgac
     1981 ggcggcttga gataatgtgt ttgatgtccc ttgcgcatat cgcttaagta agggagccag
     2041 ctctttttta gtcgttaata cataatggct ttccgtttca aaaatatgca aagctgagtg
     2101 cgagttttga gtgtaagatt cttttaattc tttcactaaa cttgtgactt ctgcttcgct
     2161 gagatttaac agtccgctta attcttcatt actgatccct tcctcgccaa caataaaaag
     2221 aagggcttca agttcactta atttcgtcat gttcggtatc tcctactgct ggataaagca
     2281 taattgattc atagttttct ttttgttgcg caatgatctg cccttttttc atcaattcta
     2341 gcaaagccat aaaagtagtg acaacttcac ttttagaagg tgactcaaaa aaagaatcga
     2401 aagtacagcc atgcgcattt ctttttatac gctcttcgat aaataccatt cgttcttcga
     2461 tcgttgtgtc atcgggcgtg atcgtttttt ccactttttg agaaaatttc ttacgttcta
     2521 agattttctg catggcacgg atcaaatcga tttttttgac ttgtcctcgc ttcaacggct
     2581 tttcagcatc cgctaaccca tcgatgttca taggttcttt tgtgtaataa agacttcgtt
     2641 cctctgcttt ttctgtcagt ctttcagctg catatttata tttacggtat tctaaaagct
     2701 gagtgaccaa ttcttctcga ggatcttctt cccataattc ttcatcgtct gtgacgaatt
     2761 cttggacagg aagcaatgtc ttgcttttga ttgccatcaa tgtagcagcc atcactaagt
     2821 attctcctgc aacagctagc tcgagtgttt tcattgtatg gatataattc atatattgct
     2881 ccgtgatcgt agcgatcggt atatcatata tatcgatttc catttgctga atcagatgaa
     2941 gcagcagatc gagaggaccc tcgaatacat ctaatttaat attgatctcc gtcaactcat
     3001 tcactctttc ttctttttct ttgctagcca ttttccaatg taaggctctg tgatttcagt
     3061 tgcacggatg gagacatccg ggtacttttc ctgtaattca tctaacattt gaaagcccat
     3121 attctcaccg cgataagacg gattcaaaga aatgtcatgg atgatcagct gatcgttcgt
     3181 tgcccagtaa ataccaataa tcccttgaat gttggttgaa ccttctggcg taaagaaaaa
     3241 aagttcataa tcgtcttcag attcgtacgt atcaatctcc ttcaacaaag aagttttacc
     3301 tgtcagtttc ttatggaaac tcaatagtcc catagcaatt ttacggtttt ctttccggta
     3361 atgtgttaac atcttctcac cttcctatga ctaagccctt ggaaaatgct gcttataaac
     3421 atccgtcatt cttttcttcg tgatatgtgt ataaatctga gtcgtagaga tatccgcgtg
     3481 acctaacaat tcctgtactg tccgcaaatc agctccattt tctagcagat gtgtggcaaa
     3541 gctatgccgc agcgtatgtg gtgttacttc tttgtaaatc ccagcctctc gtactaactg
     3601 cttcagattt ttccagattc cttgccgaga aagacctttc ccatgattat tgacaaatac
     3661 atgcatttca gatgcgtcct ttacaagtaa tggacgtgct tcgtctaagt agcgttccag
     3721 ccattggatc gcataatcac ctaaaggaat gatccgctct ttatctcctt ttccaactgt
     3781 ctgtaccagt ccaagagaaa gatgaagatc tcccaatttc aatccaatca attcactgac
     3841 gcgcatccca gtagcataca tgacttccaa gattgcacga tctcttatcc ctaacgtttt
     3901 tgtcgtatca ggtgcttcaa tcagcttttc tacttctgtc agagtcaatg tacttggtaa
     3961 tttctgtgct ttcttcggcg tatcgatatg ttgcatcgga tcatgatcag tgatacgctc
     4021 ttgccgtaaa aactgatgga atcttctgag acttgagatc atccgagtaa cagttgctgt
     4081 cgcttttttt tcttcatgca acttctccag aaaacggatg actaaaaagc gatcgacatc
     4141 ctgccatgaa gcaattttct gctcctgtag aaaatgcaag tactgttcca aatcacgttc
     4201 atagctttgt cgtgtattgg cggacaatcc ccgttcaata ttcaagtagt ggagataatc
     4261 gttgatttgc tctttcataa taatccccct catgcctctc tatcatatca gataccgctt
     4321 cattctgata gtctttttcc ataatctgag caaagaaaaa gccgtctaga cactcagacg
     4381 gactggtttc ttttttcttt ttcatagcat tcctgacaga ttccatggaa cgttagccga
     4441 tgatctttta ctaaaaaatg ataacgttct tctactactt gctccacttc aagtaaaaga
     4501 tcctcttcta cttcctcgat cgtgccgcag ttcaagcata gtaaatgatg atggaaatgt
     4561 ttggcgcctt cttttctcaa atcataacgg gctaatccat cattaaaact tactttatcg
     4621 acaattttca attctgtcaa gatttcaagg gttcgataaa cagtagcaag tccaatttcc
     4681 ggactctttt ttttcactaa aaagaagatt tcttctgcag ataaatgctc tttctcattt
     4741 tccaaaagca caagcagagt agcttctctt tgcggtgtca gcttaaaccc cgcttcatgt
     4801 agctgctgtt ttgttttttt catcgccgaa atagcattca tgaccattta ctcaacccca
     4861 acaatttata ataattacaa ataaaaaaag atataacact atgttaatta aaattattat
     4921 aagctagtta agaaaaacat gcaagggatt ctcaattaga ttttttgact agttttgtca
     4981 caccgttttc ttgtgtaatc aatccttgtt tcaaaagatt acctaatgcg cgcttaaatg
     5041 ctcctttgct gataccaaaa gctttcatga tttcttctgg atccgattta tctgtaaagt
     5101 tgatttgctg atctgcagaa cgttctaaaa tggttaaaat catttgtgca tcatctgata
     5161 tagcttcata tgctcttggc ttcaatgaaa gattcagtac accgtctggt cggacaccaa
     5221 tcactcgacc ttttatctgc tcgcctagac gaggttcatt atatcgttca gaaggatgga
     5281 taaacccaag atagaaatct tccgttaaaa cgtacgtacc tgttaatttc aagcggtatg
     5341 ctgttcctat cacatctttg tttttcattt cttctgttcc atatttgctt aaagatttga
     5401 atattttttc atctgctaaa ctgccccaaa tacggtcttt tgcatcaact ctaagggaaa
     5461 tcatcaagcg atcccctttt ttaggccata gctctgtcat tgtcggcaat tcatcaagag
     5521 atacgacaaa gtctttatct ggaagaccga tatcgacaaa cgcacctaaa tcttttcgtg
     5581 tagcagtaac gattccaaaa gcgtaatgac cgatacggct tttaggaatt tgtgtagtga
     5641 tccgattttc atgtttttga ttttggtaac cgaatccttc aactgcttca ccgattttgt
     5701 gttcaccttc tgatttgctt aagccaaagg tttgtccgtt tttttggaca aagtagtttt
     5761 tttcattttc atcaataata atacctgtaa atatagttgc taataaatcg ttcatttttt
     5821 tctccctcta tagtgaaagg ttttcttaat acatttcttt gctatcataa cataatgtta
     5881 tctacttgaa tagctgagcc ttggtttgga aaggtgaaaa aaggagtatg acaacagttg
     5941 tgtcatactc ccctttttcg aataaacggt gttaaacggc aggctcacag cctctttcat
     6001 ttgcctaaaa ttaattgctc ccatttcctc cgaaccatcc agttttacag ttgatggtta
     6061 cgatgtaaaa tggcaaagca ctttctccaa tgcctttcat caatgcagat tttgttgaag
     6121 tggcatatag attataatag ccttccccat tttcgattct ggctttttct aatctgtaac
     6181 ctccttcaac gatatatcca cgttggatac atgtagcaat cactttgctt tggacacctg
     6241 gtgcccacgt ccatgctgga ttagatgcat cggcaatatc acttgctctg gcagatttga
     6301 ttggctgatt cgctgagttt gaagaggaag gggtcgagga tgccgcttct tgctgtgctg
     6361 cttgtgcgac cgcagcttgt tgagcggctt gagctgcagc tgctgcttga gcggcttgtt
     6421 ttgcttgttc ttcagctgct tttttcgctt cttctgcttt tttcttttcc tcttcttctt
     6481 ttttctcttt atcagtgagc atcttatcta cttgtttcaa ttgttcattc aactgagcag
     6541 atagatctgt atttttcact ttttctactg cttcttttgc cgtcttgtat tggtcgcgtg
     6601 ttgctgaatc cactactttt ccgtctttaa agactatagc tgttttttct ttagctgttt
     6661 gcaattcagc atattgattt ttagcttctg tttgtgcttg ttgaatcaat tttccaaaat
     6721 ctgtgttatc cgtttcgatt gcttggatct ctttatctgc tttcaacttg atgtcatctg
     6781 ctagatgatc atcgacgatg gcaggtgcta tgaaccactc attcactttt tggatatctc
     6841 ggatcttaga ttggatatct tggtaagttg tttctaactc tgaatatcct ttttcattct
     6901 taagactgga taaatcattt tttagttttg ataaatcttg atgaatcata tctgcacgaa
     6961 taaattgatg gtgatcatct gtataaaagg cagcaagttt ctcatgaagt tcttccattt
     7021 gttgctgtct ttttgcttct gctgctactt cggcttctac tttttgatga tggtcataat
     7081 aagcccagct tcctccaccg agtagaagta ctgctgctaa aacgagataa ggtacttttt
     7141 ttgatttttt cttttgcgct ttatctggat ctgttttttc taagtttgat tcttgatgtg
     7201 ttttttcagt atctggcacg attgttattg atttcgcttc tgcttcaaac agcttaggct
     7261 ggttctcttc tttttctatt tttgcttcaa gatcagtacc ctctttgctt acagattgat
     7321 tttcagcatc ggattcacta tttatttcat cgggctctgt tgactttttg tctgtgtttt
     7381 cgagtatttc ttttttctct gcttccggca gtttattcgt tttttccttt tctaattgtt
     7441 tttcagtaaa tacttcagtt ttttctgtga tatccgtttt tacgtctttt atttttactg
     7501 tttctttacc tgtggcgttt tctctatcag agtctttttc agtttcttgt tccttttctg
     7561 gctctacttt gttttcctgt gcaatttttt cactgatcat tttgagcagc tctttcgcgt
     7621 gctcttcttt tgtatcttca cgatgtgctt tgatataagc ggatagtatc gaattttctt
     7681 cctcattatc gacgatttct ttcagttcag ctactcttct tttttgtttt gattcaagcg
     7741 tttcttcttg attctttcct gattcttccg aagtctcatg aacagttgct ttcttctgtt
     7801 catttttctc tatattagtt acttgatcgt gagcaggtgg ttcttcgtct tctggttctg
     7861 ctttttcgaa taattccatt acagattcta gaggtaaatc tttcaattcc gaccattcga
     7921 ttggatcgtt taattctgta tcaggaaaga ctgcatcttc agttgattta tcctgcatag
     7981 ctgcatctgt atttgtttct tcaattgatt cttttatttg ctgatcttct gcagttattt
     8041 gatgaccgca gtctggacag atagtattct gctccatttt tttcgatccg caatttggac
     8101 attttttcat cacttagcga tcggctcctt tactaggttt acgctaccat ttaatctatc
     8161 atattctata cgtcacgcca atagcttatt tttaggattt acttaaaaat aatgaatgaa
     8221 tttccttcct atagaaaaaa aagcttgaga ctgcgtagtc tcaagctttt tttcttttaa
     8281 aataaaccaa acagttttac tgatttctct tctggtcaat agtccacgct tattctaaga
     8341 aatcttttaa ttgttttgaa cgagaaggat ggcgcaattt tcttaatgct ttagcctcga
     8401 tctgacgaat acgttcccga gtaacaccaa atactttccc tacttcttcc aatgttctcg
     8461 tccggccatc atctaaacca aaacgtaagc gaaggacatt ctcttcccga tcagtcaatg
     8521 tatctagtac atcttccaat tgttctttta gtaactcata agctgcgtgt tctgctggac
     8581 ttgttgcttc ctggtcttct atgaaatcac ctaagtgaga gtcatcttct tcaccgattg
     8641 gcgtttcaag ggaaacaggt tcttgcgcga ttttcaagat ttctcggact ttttctgttg
     8701 gaagatccat ttccgcaccg atttcttctg gcgtaggttc tcttccaagg tcttgcagca
     8761 attgacgttg gatacgtatc aatttattaa ttgtttcaac catatgaact ggaatacgga
     8821 tcgtacgtgc ttggtcagcg attgctcgag tgatggcttg acgaatccac catgtagcat
     8881 aggttgaaaa cttaaatcct ttgcggtagt caaatttttc aactgccttc atcagtccca
     8941 tgtttccttc ttggatcaag tcaaggaact gcatgcctcg tcctacataa cgtttagcga
     9001 tacttactac taaacgaagg tttgcttctg ccagacgctg tttcgcttct tggtcgcctt
     9061 cttcgatttt caatgctaac gctacttctt cttccgcagt taaaagggag acacggccaa
     9121 tttctttcag atacatacga accgggtcat tgatttttac accggttggc gcagaaagat
     9181 cttctgtttt tgcttgttca gcttttttct cagcactctt caagctgtga attgatggat
     9241 caccattttc atccaccaca ctgatacctg cgtcttcaat cttttggatc aatttgtcca
     9301 tttcatctgc attcaaagtg aatggtgtag caagctgatt ggataaatca tcatatacaa
     9361 cttgtcgttt gggtttgttt tctttgatga aagctgctac tgctgcttca tacgtttttt
     9421 tatctgttcc atttgccata aaagaaggcc ccccttgagt agctatttgg cttgttttaa
     9481 ctgtttcgtt aaattgatga tttcaatcgt caattcaagc tcaagctgtt tgtttccagt
     9541 tcgtctggct tcttgctgca tttgtttttt taatgttatt tcatcagcta agccagattt
     9601 gctgatcaca tctagcaagt cttggatttc tcgtggcgaa ctttcttctg ccaccggtaa
     9661 atattcgatt tccaccacca accgccttaa attttcatct tgcaaaaagt ctaaaaactc
     9721 tgcaaggttg aattcataat gttgtgagac atatgcatcg aataaaaaat aaacttctgc
     9781 atatgcatca tgaataaact gaaattctcg ttcttttaaa atattacgga cagaaacttc
     9841 tttaaatgca cgatataata gaatctgctc tgccttttct acttgcgtca aaggtctctt
     9901 tttccgtgca gtttcttgtc tcgtaacctg agtgtgttga ctttcctgag gttcttgacg
     9961 attttgctga tttgtccttc gaagatcgcg cagttgtttt tgtatcgtct ctctgccgat
    10021 ctgaaactct gttgacagtt gagatagata catatcttgt tcgattggtg aaacaactcg
    10081 gctaagttca actagtaatt cttcgaggta ttcgatcttg tctttttcat tatctaaatt
    10141 tttcccttgt tttaaataac gtgatttaaa agtaaagact gtttcgcgcc catgagccac
    10201 taattcttgg aaagatgctt ctccatactt acggagatat tcatcaggat caagcttttc
    10261 tggaacgact acgacagaaa gtgctaatcg actgttttgc cgaagcaatt caatccctcg
    10321 attggttgct tcaaaacctg cgttgtctcc gtcatagcaa aagaccaatt ctttcgtcag
    10381 cttttccatt tgttggatct gttgagctgt tagacttgtc cccatagaag ctaatccagt
    10441 tttgatacca gcctgccatg cagcaatcac atccataaac ccttcgaaca acaaaatttc
    10501 tccgtttttc cggatatcgc ttcttgcttt atcaagatta aataaaactt gtcttttatt
    10561 gaacagttct gtttctggac tattcaagta tttgggctga tctttttcct gccctttttc
    10621 aggtgcaagc cagcgtcctg aaaaaccgat cgtctggcct tgagaattac gaagtggaaa
    10681 catcactctt tgataaaaac gatcagacat acggccatca tcatgcgtga caaacaatcc
    10741 agagcgttct aacaattcat ttgaaattga ttcattcttg aatacttgct gaagaaaaga
    10801 acgctcatta ggtgcaaaac ctatgttgaa ttcttcaatt aattctaaag acaacccacg
    10861 actttgcaaa tattctaaag ctggctgtcc agcttttgta tgcaatagca tgtgatgata
    10921 gatttccgct gctttttcat gagcagcaat cagtttcccc gtagcagatt caggattttg
    10981 gacagctata gtacgctgac gccattgatc ttctaacggt atctgttcga agtctgccac
    11041 ttttaccact gcttctggaa aacttagacc ttctagttct tgaagaaaag taaacacgtt
    11101 tccgccttta ccacaaccaa agcaatgaaa aatctgcttg tcttctgcaa cagaaaaaga
    11161 cggtgtacgt tcttcatgaa aaggacacag ccccaagtaa tttttaccag actttttcaa
    11221 ctggacatat tgtccaatca cctcaacgat attcgtttga ctgcgtactg tttcgataac
    11281 ctcttgagga atccgttgag ccattttttc accccctgct ctattgatat cttttgggtt
    11341 taacagaaga tatttcagga gaataaccgg taaaaaatcg cactaactga aatcagtgcg
    11401 attttaaagg acacaattat acatgtttga ttgtatcata tttcattgct ttttcaagta
    11461 taacacattt ctatctcatt aagcatcaat ttgctactct tttcagtaac tgattttgaa
    11521 tatcagcctt ccagtacaat actcgaagaa caatatttac gagcatgaat acaaagaagt
    11581 atcctacgct ctctcccaac cctaagttta cttccaaaat tccatggaac agcattgcag
    11641 ctacatatat ccctacgatc gtcgttactg ctaggaagat gcgcaatggg ttgaagggat
    11701 aacaagcttt tacaactgcc atgcaactga tcccaatcag caagtaatac atcaaagtag
    11761 tagtttcagc atttccccat gcgaatgttt ttccaagtag atacaccgca atgatattca
    11821 ctactacaag caaggcattt ggtaaagcat taataagtgc tgtaggcaaa taacggtaag
    11881 tgatttttct tttatcttgt tcaaaagata aaaagaagga aggataccct tcaatcgcta
    11941 aatcaatcag cgtgatttgg atagggataa acggaaatcc aattgctgta acggcacata
    12001 taatcgataa aataaatgaa taaatcgttt tgataaaaaa gatgcctgag actttcgtca
    12061 cattgttgac cactcggcgt ccttcaaaca ggacttctgg caatgtagta aaatcagagt
    12121 ccaacaatac cagattcgca atctgacgtg ttgctccatc accttctgcc atagcaatgc
    12181 tgcaatctgc ttctcttaac gccaaaacat cattcacacc gtcgcctgtc attgcaaccg
    12241 ttctgccgct ttctttcaat tcatttacca gcaatttctt ttgctgcgga ctcactcgtc
    12301 caaaaaccgt atagcgatga gcagcttctc gcacttccat ttcttcagta atttgagaaa
    12361 gatcgacata cgcatcataa ttcggtaatc ctgcacgtct agcgatattg gagacagtaa
    12421 aaggattgtc tccagaaatc actttcagat ccacaccttc ctcatgaaga taagctagtg
    12481 tttcttgagc gttttttcgg attggatcat cgatttcaaa cagagcaacc ggctcaacaa
    12541 atgctggttt ttcttcgttc aattgctgat ttggagcgat ccccaacata agtacgcgat
    12601 agccattcgc ttgggctgtt tttagactgt ccggaagccg atcttcttcc accaaacgtt
    12661 caggcgctcc tacgtacacg actcccagtt ctggaaattc catcgcgccc catttgcgat
    12721 cagaagaaaa tgcgactttg tttgtcacat cataccgatt agaaagctca aaataatctc
    12781 tcatagcccg catagtgatg ttgttatcac tgctttctgc cagatacgtc cccataattt
    12841 ctgggatggc tttctcgtac agcggatgta gtgcttctac ccgctggata ctcattttcc
    12901 cttcagtaat ggtccctgtt ttatccaagc ataatgtatc gacatgggcc agcgtttcaa
    12961 ttgaatacat gtcttgaaca aggattcgtt tttttgccag tttggttacc cctgtcgtta
    13021 atgcaatact tattagcaat accaaaccct ttggaagcat gcctaacaaa gctgctgcag
    13081 atgcaataac agaaattttg atagaagcat cgcggatgaa cagtgcttcc aaaaatagta
    13141 tgatccccaa aggaataatc acgaaactag tgaatttgga tactttgcga atcgaatcta
    13201 caagttcaga acgaatagct ttgtgagtct ttgcctcgct agtcaagcgg acagcataat
    13261 tatctgcacc tactcggata acttcagcca tgacagaacc gcttgtcaaa aagcttccag
    13321 aaagcaattc agctccagtt tctttgacaa tcaaatcaga ttcgcctgtc aaaagagctt
    13381 catttgcttc tgcccgtcca gatataacct gtaaatcggc tggtatctgt tctcctgctc
    13441 cgatttttac caaatctcct aataccagct ctttagtaga aatcgattgt tctttaccgt
    13501 cccggatcac tagtacttct gattgggaaa caatcgataa tttccgtaca agatttcttg
    13561 catgtatttc ttgataaatt ccaataacga tattgacgac aataattgct aaatacgcca
    13621 tgttggaata cgcacctaca aataacagac aaatcccaat accaaagttc agaaaattga
    13681 ataacgtcaa tatattatcg ctgaatattt gttttgtact ttttgatgca tcttcctggt
    13741 agtcattttg ctggccagaa gccattttct gaactacctc ttgctgtgta agtccattca
    13801 ttttcttttt ctccattttc cgccaacttt caaaaataat cacgtgttta agtctagcgt
    13861 gttccaagat taaaaacaac ttgtttttat aaaatttata gaaaaacaca cgaatgattt
    13921 tacaaaaaag atgccaacct ttttgtttga atcacccgtg tgctgttttt attatcaatc
    13981 tatctttact tatattgttc ctccaaacgg ctcatccacc aacctagtgc tgtaccggct
    14041 ataaaaagaa caggacaagc tagtacccca gcaactccca atcccgcgta atcggtagga
    14101 atgatcataa tcgttgaagc aaaaactaca cctaaaatga aatggaatag cttgctatat
    14161 gcctttgaga aaatgtaatc catgattttt gacaatccaa gaacacaaag aatcccacca
    14221 attccgatcg gcacaatcac ttcaagtcgt acttctttaa atccgtcagc catcgcttta
    14281 tacaatccca tatacaccaa aaaattagaa gggctcaatc ctgggacgat catacccaaa
    14341 ccaatcaatc cgccggcaat cagccatgtt ccaaaattct gatcgacttg cccgtcaaat
    14401 aattgagcgc cgtataataa aaacaaataa gccagaacaa aagtaacaac catgatgatc
    14461 acatcagaag tatctcttcc ttttttccct gcttctttcc ataacgcagg aacagttcca
    14521 gcgatacatc cgacaaaaaa ccataatatc gttgtttcat acgcacctaa taaaaaactg
    14581 actaaaaaag aaagtagaaa gatgcctgtc actccgccta gaccaacagg cagaaaaaac
    14641 aaaacatttt ctttgaaatt ttttgtaagg tgggctaaaa aagaaatcag ccgctcatac
    14701 atgccaaaga cagctgctaa tgcaccaccg ctgactcctg gcaagataaa tcctgaaccg
    14761 ataaacattc ccttcacaaa ccgtaacatc cagtctttgg ttgtgtaccc cacttcttga
    14821 ttttccattt tttgcctttt ttccactatt tgcgtactcc ttctttcatt taattttatt
    14881 catgattgaa catttcctgc tattttactt aaagactttt tcataggtct ctattatttt
    14941 ttcattcatt ttgacaatat caggataaaa catgttacct ccattatgat agagatagcc
    15001 gccattgtaa agcaaggact ggatccgcca atatcggtat tgtttccctt cctcatttcc
    15061 taaaagtggg ctcagcacat ctttagaata cgcttctgct aattctactg tgttttctcc
    15121 gccatgattt tttacatagg caatataatc tttcccaaaa ttatatgctt ggacagctgt
    15181 ccataaatcg catccttgtt tctttgcttc tactatcatt tccgccaaat atttgacacc
    15241 ttgatcaata ctgtcagctg gattatcaat gatctcagct tctccatgca gactttccga
    15301 gctctgcatg agatctgtcc cttttccttt tgattcggtc aatattatcg ccttgatcaa
    15361 attctcgtag ttttccatat gataattttt tgcagctgtt gttatttcta tttgatagct
    15421 ttccactcgt tttaccgaac gataagttct tcctcataaa aacaacaccg caccaataac
    15481 cgtcagaatg atcatgtaaa aaagaatacg gataatagat aatcgttttc gcttcatttc
    15541 atcacctagt tattttgaca tcttttttta tcttactatt tctttatctt cttggctatt
    15601 tcttccttga tttctgtgta cgccttaaga aaaaatgaat tttcctgtat tttttgacat
    15661 cttacgaaaa tgatcgttgt ttttcagtaa aaacaattgc ccaatgactg atataatcgt
    15721 tatactttac acagtaggtg attatgtgaa aaaagaaaag aaatatgcaa aaatgccaga
    15781 tgggagcgaa atttactatg aaaagagcgg tcaaggcttc cctctctttt tactgcatgg
    15841 caatgacggc agcggccgct ttttttcaga acaggtccct gtactcgaac gctactatac
    15901 cgtgtatcta gtagatagcc gaggacatgg tcgttcgaca aacgaagcat ctatgttgaa
    15961 ttttcagtta atggccgagg atctgaatac gatcatgttg ctggaaaaaa tcgatcaggc
    16021 agattttctt ggatttagtg atggagcaaa tctagcactg gtatttgcca gcagcttccc
    16081 taaaaaagtt catcgattga ttttaaattc tggaaacacg cttgttaaag gcgttcgttt
    16141 ttctgccaga gtcatcagta atattcatta tgcatgggta tggttactct ctttatttcg
    16201 cccaagtctt cgcaaaaatc ttttagttat caaacttttg ctgcatgaca tcgggcttac
    16261 agaaaatgat ttaaaaaaaa tcaactcccc cactttgatc atcgtgggaa aaaaagatgt
    16321 aatcaagcta aaacattctt tgtatatagc taaaactata ccaaaagctt cctttgtgct
    16381 tgtgaaagaa caaggacatg aattagctag aaaagatcct gaacgcttca atcgagaagt
    16441 tcttcaattt ctttctgaaa cataactatt aggaatagaa ggtgatttat ttgttaaaaa
    16501 ataccataca atggctgaaa aaccacctag gactgttcaa aacaatcttt ttgatttctg
    16561 tcattgtcat tattgtcggt gaattgatgt ccatcggtaa aactctatct atccagcaat
    16621 taggagaaac gtttgccact atacctgtat ggaaaagcgg actaatgcta ttgattggtc
    16681 ttatctctgt gttacctatg gttggttatg atattatttt gaatcggatg cttgaacaaa
    16741 agcagaatcc tcgttacctg tttgagacaa gctggctgat caatacgatc aacaatattg
    16801 ccggtttcgg cgggtttgtt agtgtggggc ttcgctctga actatatgga caaaagaaag
    16861 agagcagaaa cgtgatccaa gcattatcga aagttttctt gtttttgatg gctggacttt
    16921 ctatttacag tctgctttct tttttacttg tagtcttcac gccagttgct ccttttttga
    16981 agcaatattg gatatggttg atcggcggcg gtctatattt tcctgtcgtc tttttattta
    17041 ctactttcaa aaagaaagga ttccttggtg gtacctcact taaaactcaa ggacagctat
    17101 tgctagtttc attgttggaa tggaccggtg tcctgtttag tttcctttct gttggttatt
    17161 taatggaaat ccggattgat ctgtggcaaa caattccatt attcattgct gcttcagtga
    17221 taggaatcgt gtctatgatt ccaggagaaa ttgggagttt cgatgtaatg atgattatcg
    17281 ggttgtccgc tattggtgtg ccaagagaaa tagtcgttgt gtggatcttg ctctatcgcc
    17341 tgttctacta catcattccg tttttgattg gaatcgtctt tttcttcaaa aatatcggtt
    17401 ccacttttga tcagcgttat tctggtatcc ctaaacaatt agcaacagaa attgcgcata
    17461 aaatcgtggt tgtcttatta tacttttctg gaatcatgct agtactttct gccactatcc
    17521 cgcaagcttt tacagagttt cgctggcttc atagtttgaa cccattgaaa tttcatttta
    17581 ttatccaatt tcctagtata ctattgggat ttcttttaat cattatgggc agagggatcg
    17641 cagcacgtgt gaaacgagca tatttgccta caatcttctt gattgttcta gctttacttt
    17701 atgttttatt aagtgatttt agtttcacac cggtggtttt cttgtctatt ctgcttctga
    17761 tcattcttgc ttctaaaaac gaattatttc gggaacaatt gatctattca tgggagtggc
    17821 gtacgatcga tggaatcatt attggtgcac tgtccttgct ttacatcgtt attggggtat
    17881 acaatctgcc ggatttccct catcggcgtc accattttat ttcctttttc ttatttcctt
    17941 ctgaaaagat ttggttttcg ggattgttgg ccatcatcgc tgttagtttc atgatcgttc
    18001 tatttgttca tttccttcaa ggagaaaaga aacagattgg cgaagccttt aatgaagaaa
    18061 aggccctgaa gatccttaca acttatggag gaaactccga tagtcaattg atcttcttaa
    18121 aagataagcg gatgtttgcc tatgaaaaag acggtgaacc aactgttctt ctccaattcg
    18181 cttgcttcaa taataaatgt attgtaatgg gtgatccttc tggtaagaaa gaagattttc
    18241 cagaagcaat cgaagctttt atcgaagaaa cagatcgact atgctattta ccagttttct
    18301 acgaaacaag cgaagagatt gttatgattt tgcatgaatt cggctacgat ttcattaaga
    18361 tgggggaaga agcttatgta gacctgaata gttttacaac ttcagggaaa aaaatgaagg
    18421 gcactcgtgc tgtcttgaat cggatcgaac gagaaggatt tacatttgat gtcttacaac
    18481 caccattttc tactgagcaa atgagtactt tcaaaaatat ctctgataat tggttgggtt
    18541 cacgaaagga aaaagggttt tctttaggct ttttctctga agattatcta caaagagcgc
    18601 ctattgcagt tgtcaaaaat acccaagaag aaattgtcgc ttttgcaacg atcatgccta
    18661 cttacacgaa caataaagta ggaacgattg atctgatgcg atatgattct aaaaaagcac
    18721 cttctggcag tatggatttc ttgttcttgc atttgtttgc ctatatgaaa gaagaacata
    18781 tccaatggtt caatttaggg atggcccctc tttcaaatgt cggaacttcc agaaagagtt
    18841 ttttacagga aaggattgca tacttggttt acgagtttgg ttctcatttt tattctttcc
    18901 atggattaag agaatataaa agcaagtacg ctacaaactg ggtctcacgt tatactctat
    18961 attctagaga tagttggatt gcatatgtta tgattgcttt gctgattatt gataatgcgc
    19021 cagttgagca gacacaaggt agaataagtg gtttgaaaaa atggatacga agaaagtatt
    19081 aaaaactgca taccgataga tgaacactct catgatgaat aaaagagact gaagtaaaac
    19141 gaaagttcat gcttctacaa tctcttctta tacaattgaa gaacaaagag cggtccaaac
    19201 agaaatcctg tttggaccgc tcttttattt taaacatttt tcattaccaa aatattcgag
    19261 tcgcgtttct tatgcttcga tctctgtaac gatacctgaa cctactgtcc gtccgccttc
    19321 acgaattgag aatgtcgttc cgttttcaac agcgattgga tggatcaagt caacatcaat
    19381 cgtcacgttg tcaccaggca tgaccatttc tgtatcttct ggcaatgtga ttgttcctgt
    19441 aacatcagtt gtgcggaagt agaactgtgg acgatagttg ttgaagaatg gagtatgacg
    19501 tccaccttct tcttttgtca acacgtacac ttctgctttg aattttgtat gtggagtaat
    19561 ggaacctggt ttagcaagta cttgtccacg ttcgatatcg tcacgttgga tcccccgtaa
    19621 caacacgcct acgttatccc cagcttcccc gtaatctaac gttttacgga acatttctac
    19681 acctgttaca actgcttttt gtgtttcagg tttgatccct acgatctcta cctcatcacc
    19741 gacacgaaca gcaccacgat caatacgacc tgaggcaaca gttcctcgac ctgtaattga
    19801 gaagacgtct tccactggca atagtaatgg tttatctgta tcacgttctg gtgttgggat
    19861 atattcatct actgtatcca tcaattccat aatagcagct tcagcatctg gatcgccttg
    19921 caatgctttt aatgcggaac ctttgatcac aggagtgtca tcgcctggga aaccatattc
    19981 gctcaataac tcgcgaactt ccatttctac caaatcgatc aattcttcat catcgactaa
    20041 atcaactttg ttcaagaaaa caatcaggta ttttacacca acttggcgtg acaataaaat
    20101 gtgttcacgt gtttgaggca tcggaccgtc agttgcagaa acaactaaga ttgcaccatc
    20161 catttgtgct gcccctgtaa tcatgttttt cacatagtcc gcgtgtcctg gtgcatcaat
    20221 atgcgcgtag tggcgttttt ctgtttcata ttctacgtgt gcggtattga tcgtaatccc
    20281 acgttcacgt tcttctggag ctgcatcaat actagcatag tcttgaggat ttgctaggcc
    20341 ttttttgcct aatactgtag tgatcgcagc agttaaagta gttttcccat ggtcaacgtg
    20401 tccaatcgta ccaatgttaa cgtgtggttt acttctgtca taatgttctt ttgccataat
    20461 ttacaaacct cctaaataat atagatcact gaaaaatttc agctctcacc tttttattat
    20521 agtctttttt tgactaaatc aaaaagaata cgtccgactt actttttgta agattcgaac
    20581 taagcttatt atacgtcaat attggtcaaa gtcaactaag agcactcgtc tgtcttatac
    20641 gcgaaaaaag taccttttat aaataaaaaa atgtgttttt tgagaaaaac ttcaagatag
    20701 tccttaactt tcttttgaag caataagaac aaaatgagga aaagtttaaa attcagctgt
    20761 tgccaacaac tttcaataga cgaaatcttc tatttcgtta ataataagga aagaggtgaa
    20821 gtacatgaaa aaattaattg gcgtacttgt cgttttaggc atatttctcg gcggaagttt
    20881 tgcagcttat cattattttt acggcggcga agcttattat acaaaaatca cgacgaatgg
    20941 cgaaatgtca gctacccaag cagataacgg agagaaattc acgacttata cctacaagca
    21001 agcggcttat aataaagatg gtgaaaaaaa acaggtgacg cttcgcgaag aaagagaaca
    21061 tccattaaag atgaatgcgt atcttaaact caaagtcaat cctcgtaaag gtgtattaag
    21121 ctgggaagaa ataaaggctt ctgaagtgcc taaaaatgcg gcagaaaaaa tcgataatta
    21181 gtaaatggtc ttaaaatttt attagataaa a
//
LOCUS       DACGEU010000046        21121 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.046, whole genome shotgun sequence.
ACCESSION   DACGEU010000046 DACGEU010000000
VERSION     DACGEU010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21121)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21121)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21121
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.046"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            98..1264
                     /locus_tag="IXR40_001613"
     CDS             98..1264
                     /locus_tag="IXR40_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAQ4361467.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            1494..2141
                     /locus_tag="IXR40_001614"
     CDS             1494..2141
                     /locus_tag="IXR40_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysis protein"
                     /protein_id="HAQ4361468.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            2225..3169
                     /locus_tag="IXR40_001615"
     CDS             2225..3169
                     /locus_tag="IXR40_001615"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HAQ4361469.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            3304..4755
                     /locus_tag="IXR40_001616"
     CDS             3304..4755
                     /locus_tag="IXR40_001616"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HAQ4361470.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            4776..5612
                     /locus_tag="IXR40_001617"
     CDS             4776..5612
                     /locus_tag="IXR40_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HAQ4361471.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            5612..6271
                     /locus_tag="IXR40_001618"
     CDS             5612..6271
                     /locus_tag="IXR40_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAQ4361472.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSIHQS
                     I"
     gene            6397..7086
                     /locus_tag="IXR40_001619"
     CDS             6397..7086
                     /locus_tag="IXR40_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361473.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PKDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            7092..8048
                     /locus_tag="IXR40_001620"
     CDS             7092..8048
                     /locus_tag="IXR40_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HAQ4361474.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHPIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            8092..8604
                     /locus_tag="IXR40_001621"
     CDS             8092..8604
                     /locus_tag="IXR40_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4361475.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSGVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(8860..9408)
                     /locus_tag="IXR40_001622"
     CDS             complement(8860..9408)
                     /locus_tag="IXR40_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAQ4361476.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(9497..10678)
                     /locus_tag="IXR40_001623"
     CDS             complement(9497..10678)
                     /locus_tag="IXR40_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HAQ4361477.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(10914..12422)
                     /locus_tag="IXR40_001624"
     CDS             complement(10914..12422)
                     /locus_tag="IXR40_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HAQ4361478.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATCLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            12581..12772
                     /locus_tag="IXR40_001625"
     CDS             12581..12772
                     /locus_tag="IXR40_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361479.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            12975..13892
                     /locus_tag="IXR40_001626"
     CDS             12975..13892
                     /locus_tag="IXR40_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="viral A-type inclusion protein"
                     /protein_id="HAQ4361480.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            13885..14958
                     /locus_tag="IXR40_001627"
     CDS             13885..14958
                     /locus_tag="IXR40_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361481.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            15106..15624
                     /locus_tag="IXR40_001628"
     CDS             15106..15624
                     /locus_tag="IXR40_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361482.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            15605..15997
                     /locus_tag="IXR40_001629"
     CDS             15605..15997
                     /locus_tag="IXR40_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HAQ4361483.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVVFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            16073..17008
                     /locus_tag="IXR40_001630"
     CDS             16073..17008
                     /locus_tag="IXR40_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HAQ4361484.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            17141..17920
                     /locus_tag="IXR40_001631"
     CDS             17141..17920
                     /locus_tag="IXR40_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HAQ4361485.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            17913..18230
                     /locus_tag="IXR40_001632"
     CDS             17913..18230
                     /locus_tag="IXR40_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HAQ4361486.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            18474..20084
                     /locus_tag="IXR40_001633"
     CDS             18474..20084
                     /locus_tag="IXR40_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAQ4361487.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            20241..21089
                     /locus_tag="IXR40_001634"
     CDS             20241..21089
                     /locus_tag="IXR40_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAQ4361488.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
BASE COUNT         6868 a         3749 c         4221 g         6283 t
ORIGIN      
        1 agtttttgaa aaatttctga aaaaattaaa cttcttagtt gattcttttc ttttttagta
       61 ttaacgtaat agggtagttt ttttaaggag gaaaatcatg ttagagaaaa ctttatacaa
      121 tcaattattt tcacgttctt tctcgctccc tgtcgaagta aattattggg acggtacaac
      181 gaaacaatac ggagatacgg acactcctcc ccaaatcaaa atcaatatcc atgaagaaat
      241 cccaatgaaa gagattacaa gtaacgcttc tttggcacta ggagaagcct atatggatca
      301 tcgaatcgag atcgagggaa gtatccaagc attgatcaac gatgcttatc agcaagcaaa
      361 cagcttttta cgaggaaaag attatctaaa atggctgcca aagaaagaaa aacatacgaa
      421 acaaaaaaac aaagaagata tccatgcgca ttatgactta ggtaacgact tttataaact
      481 ttggctagat ccaactttga cttattcttg tgcttatttc aatacacctg aagatacgtt
      541 ggaacaagca caaatcaata aagtccatca tatcttagac aaactcttta tcaaagaagg
      601 cgaaacgttg cttgatatcg gttgtggctg gggaacattg atgttcactg ctaccaaaga
      661 gtataatgtc aaggcaactg ggatcacact aagtgaagaa caatacgatt tgattaccaa
      721 aagaataaaa gaagaacatt tagaagataa atgccgtgta ttattaatgg attaccgcga
      781 actaaaaggc gaaacgtttg atcatatcac aagtgtaggt atgttcgaac atgtaggttc
      841 tgaaaatctt gaaggttatt tcaaagtggt aaaagattta ttgaaaccaa aaggaacagc
      901 tttgatccat ggaatcagcc gacaacaagg cggtgcgaca aatgcttgga tcaataaata
      961 tattttccct ggcggttatg tccctggtgt tactgaatta gttgataata ttacaaaaaa
     1021 cgatttgcaa ctgattgatt tggaaagctt acgtcgtgac taccaattga cattagaaca
     1081 ttggacaaag aattttcatc aagtccaaga tcaagtcacg aaagaaatgg gtgattcctt
     1141 ctatcgaatg tgggatctat atttacaagc ttgtgcagct tcatttgaat caagtaatat
     1201 cgatgtgatt caatatttgc ttgttcaacc tggaaacaat gacatcccaa tgcatcgtgc
     1261 ataattgagg caaaagtact gtttaaagac tatttaaaaa gaagctaagt tttatgatgc
     1321 tccagaagtg aacttttttg tctaacttct aggattgtct ctaaagctta gtttcttttt
     1381 ctttatattt tcataataaa agtttggttc tttaattttt aaacatgaca gaaaattttt
     1441 tcttcgttat acttgtaata gaatactatt ttataacaaa ggggatcgaa tcaatgaaaa
     1501 aaactgttat ttatactagt ttatttgcag ctttgttttt agctgcttgt caatcaaata
     1561 ccaatcaagg cacatctggg aatacgtctt ccagtagcga acagcgctct tcacaggtat
     1621 cggactcctc aacaaaagca agcacatctt cgtctagcca gacaaaaagt tctagtgaag
     1681 caagtactca gtcagatatc aaagtgtctg cagctcgtgc gatcgaattg ttccaagata
     1741 aatacccaga tactgcaatt actagtttgg aattagatag tgattgggga tcttacttct
     1801 acaagataga aggtgtcgat gatcaaaaag aatacgaagc aagaattgat gctcaaaatg
     1861 aaaaaatgga gacagagaat ccagaaactc tagatcgaga tgaacaaaat ggtcaaaaga
     1921 aaaaagaaga tggtctggat gttgataaat tgatcacgat tgaggaagca gcaaaaatcg
     1981 ccgtcgacaa agtaggaagc ggtacggcaa cagattggga tttggataaa gatttaggta
     2041 ctacttattg ggaagtcaaa gtaaaagacg gcaatcaaag tacatcagtc aagatcaata
     2101 gccaaacagg cgaagtactg tcaactgaac aagatgatta agaatttctt cggaaaacaa
     2161 gagttgattt ttcttttagt catgatacac tagacaaaat aacttgtttg aaggagcgat
     2221 ttacttgagt ttagaaacga cctttgccaa tcatatcttt gccaatcctt tgatgaatgc
     2281 atctggtgtc cactgcatga ctacccagga attagatgaa ctggctcatt cagaagcagg
     2341 agcatttatc actaagagct gtacgatcaa tgaacgaaaa ggaaatcccg aaccacgcta
     2401 ttttgatgtt cctttaggga gtatcaattc tatgggactt ccaaacttag gtttttctta
     2461 ttatctagag tatgctcttg cgtatgaaaa agtgcaggaa aaccaaaatc aaccgttatt
     2521 tttttccatt gccgggatga gtgtccagga aaacttggaa atgcttgaga aaatagaaaa
     2581 aagtgggttt aatgggatca ctgaattaaa tttatcttgt cccaatgtgc ctggaaaacc
     2641 acaactagct tacgattttg aggccactta tgaaacactg aaagaagtat tcagcatctt
     2701 ttctaagccg ctaggaatca aattgcctcc ttattttgat tttgctcatt ttgatcagat
     2761 ggctgatatc ttgaatcagt ttccattgac ctatgtcaat gctatcaaca gtgtgggcaa
     2821 tggtttgtat atcgatacag aacaagaagc agtagtcatc aaaccaaaag aagggttcgg
     2881 cggcattggc ggagagtata tcaagccgac tgctttggcg aatgttcgcg ctttttatac
     2941 acgtttgaaa ccagaaatcc aaatcattgg tacaggtggg attcggacag gacaagatgc
     3001 atttgaacat ctgctatgtg gcgcaagcat gttacagatt ggtacagagc ttcataaaga
     3061 agggccggaa attttttcta gaatcataaa agaattaacg cagattatgt cagaaaaagg
     3121 atatacgtca attgacgaat ttaaaggcaa attacgcacc atttcatagc aaagagacga
     3181 aggtcatgat tgatcttcgt ctttttttat aaaaaacact cgtctgttca ttcctgtgca
     3241 agcgtactca ttgtatgtta gacgaacttg tgggaaaata acagaggcaa aaaggaggat
     3301 aatatgaatg atgcaacaga attagcaaaa gagcttaaag aaaaagaatt tagttttcaa
     3361 gaactagtta cggatataca gaaaaaaata aagaagcaaa atcatgaatt gaatgcgttt
     3421 gtcgcgcttg aaccattcga gagtaattcc cacgagctat tgattcccca gtcagaaaaa
     3481 gggccattgg ctggtatccc atttccttta aaaatgctcg gtcaagaaaa aaagggatgg
     3541 ctagctactt caggatctcg tttatttgaa acacaccgag cttctcatac atctaattat
     3601 gtgcggcaag cagaagcgat aggtctagtt ccttttggac aaaccaatgc gccagagttt
     3661 ggtttcaaaa atattacaga cccagtcatc tatggcccag caagaaaccc ttggaacctt
     3721 gaatgtacac cgggcggatc aagtggagga gctgctgctg cagtttcatc aggaatcgtt
     3781 cctttagctg gtgctagtga tggcggtggt tctattagaa tacccgcttc gttttgcgga
     3841 ttgattgggc tgaaaccttc gcgagggacg atgccagttg gtccatatgc ttggagagga
     3901 tggcaaggag ctgctattga tttcggcttg acagtttcta tgagagacac ggaggcttta
     3961 ttttatggga tgagaagtat ccattccggt gcgccatatc aagtatcgcc agttgagtgg
     4021 caaacacatc caagaaaaaa acggttgaag atagcttttt gtgttgattc accgatccac
     4081 tcacagatta gtgaagaggc agtacttgct gtaaaaaaag ctgtagattt ccttggaaaa
     4141 gaagggcatg atttgacaga gattccttac ccactagatg gtcgtaaact gatcacgtct
     4201 tattatcaga tgaatggcgc agaaacagca gcaatgatcc gctcgattga aacaggcatc
     4261 cagcgagctg tcagaaaaga agaacttgaa cccatttctt ggactttgtt ccaatatggt
     4321 cagaagctct ctgccgctac ttacatcgat tctctgcatg tatgggatga agcagcaatt
     4381 gtcatggaaa acctacatca agaatacgat ctattccttt caccaacgac tgcatttacc
     4441 gcccctaaaa tcagcgaaga tttgcaaagt gatgcgataa gagcacagat ggaacacatc
     4501 agtgattgtt ctgaagtaga aggtttagac gttgtttctt ccatgtttga ggagagcttg
     4561 aagatcacac cttatacaca gttggctaat ctgactggac aaccagcaat cagcttgcct
     4621 actcatttga caaaagaaaa catgcctcta ggaatccaat ttatggctgc cagaggaaga
     4681 gaagatttgc tatttcaaat cggctatcta tttgaagcaa atcatcagtt ccatttacca
     4741 aatccatgga aatagcagaa acaaggagaa gaagaatgaa gaaaaaaaga ttgtttgctc
     4801 taataactag tgcctttttt attttaagcg cttgcggtac agctgccgct aatcaggaag
     4861 ataacagctg gagtaatgta gaaaaaaaga aagaattagt agtagcgact tctggcacac
     4921 tgtttcccgc atcttattat aatgatcaaa atgaattagt tggttatgat gtagatttgg
     4981 caaaagaggt ggctaaacgg ttaaatgtca aaatctcctt taaagaatac aacgtggatg
     5041 gacaaatcac ttctgtttca aaaagagaat cagattttgc tgcgaacgat tttggtatca
     5101 caaaagaaag agaaaaaaaa ttctcccttt cagagacttt caaatattca tttgacagta
     5161 tgatcgtacg aaaaaaagat gattcaggaa tccactcact tgaagatctt aaagggaaaa
     5221 aagcagctgg cgaacccaat actagctata tgcgtttagc ggaaaaacac ggagctaaat
     5281 tagtcacata tgacaatgcc acgaatgatc agtatttaag cgatgtagca aatggtcgaa
     5341 cagatgttat tctaaatgat tattatctgc agaaaatggc cgtatctgct ttaccagata
     5401 tccctgtaaa aatactggag aacgtttatt tcaatgaaaa cgaaagtggt tttttattga
     5461 aagaaggaaa tgatgctctg aaaaagaaaa tcgatggcgt attaaaagag atgaaagaag
     5521 atgggacgac aaagaaaata tctgaaaaat attttcaaac tgatgtttca gtcaaaccga
     5581 aagaaacgat ggctgagtcg gtgagtgagt gatgtacttt cctctaattg atttttccct
     5641 catgtggact tcacttcctt tcgtactgca aggcttggta tacacattag ggattggctt
     5701 cgtgtcgttt cttttaggaa atttggtagg gttgcttttg acagttttag gtcttttgga
     5761 ttggctgcct ctgaatgtat ttattcgttt ttatttatcg ttctttagag gcattcccgc
     5821 actagtcctg ctgtttctgt tatatttcgg gttaccttat caattaagtg ccttaacggc
     5881 ttcagtcatc tgctttacga ttaccagcag tgcatttatt ggtgaaatct atcgaggatc
     5941 actagcaggc gtttcttcag gtcagtggga cgctggttta gcttctggtt tttctttctt
     6001 tggggtattg aaatatatcg ttttgccgca agcttttcga atctcagtac cggcactcag
     6061 taacgtagct atggatctag tgaaaggtac ttcgttagca gcaacaatca cagtgccaga
     6121 aatatttcaa aaagcaaaga tcataggcgg tcggacattc gattattttt ctctctatat
     6181 tttagttgca ctgatttatt gggtcatttg tatcgggatc gaaaaagtgc aacagtattt
     6241 agaaaaacgt tctatccatc agtcaatctg aaaaatagaa atggtgctag cgtggctggc
     6301 accatttcta ttttttgttt cttgtatatt ctgcctagta ttttaaaacc atttcatgta
     6361 aaatgtaaat cgaaaatatg ttcggaggta gaaaacatga agaccccgct aaccatcgaa
     6421 atagaatcct cgttatacca atattgcatc gagcaaggcg gcttggttgt agaagaagtc
     6481 acgatgcctg atgaccaagg aattgtagat acgcttagct gcttgacaaa atttgatgga
     6541 agccgagaat ggcgatgcta tgagctgaaa gtgacaaaag cagattttcg ctctacagcc
     6601 aaactgtcat ttgttggaca ttataattat tttgttttac caagtaaact atatgaagaa
     6661 gtaaaaactg aaatccctac aggaataggt gttttagtgt atcgtccgta cacggttgaa
     6721 gaggagatgc ctgcctctgg tacatttctg attgcgaaaa aagcagcaaa gaaagagctt
     6781 gctgtaccgg aagaagcttt gacaaaccgc ttcatggctt ctttattcag ggaagtaaga
     6841 aaagcaaagc aaatggagcg aggcgtaaaa tattttccaa aagatcaatt gtacaaagaa
     6901 ttgaaaagac gttcagaaaa tcaagatcca ttttctaacg aacgatatta tgaacggttt
     6961 ttagaggaaa tagctagtca ggcaatcaat gagttgcaag aagaagttat cgcgcttcag
     7021 catgattatg aatatttgag gcaacaacag cagatccgtc ggttgcctac agagccattg
     7081 gagtgaaaaa tatgtactat ccttatttaa gaggaaaaca atttgaccta ttagcattaa
     7141 aagaagcact gtcgcgagga ttgctctcca ataaaatcca accagtgatc gaaccagtac
     7201 gtgattccgc tacgcttaaa aatgtgatcg aattatttca aaaaaagcac catccaatcg
     7261 ctgtgatcca aaatccccaa gtaggacaat tcaaattatt cgatcagcat gtgcacagtt
     7321 ggacagtcaa agaaaatagc tctgtcgtcc ctgcacagat cttaacgcca gaaaatctca
     7381 gtgaagtact ggattcacct ccagcgtttc ttgttttcga tggacagcac tacccaaaag
     7441 atacagaggt gtggaaacag ttggcaggag ttgattcgaa atttttgata ccagatacta
     7501 gtcgctttcg catctggctg cccgaaaaca aaattgtgat ccgtgactct tttcaaacga
     7561 gaaagcatgt tgaaagttat gcagataaaa cagatgactt ttttagtgat gactatcttt
     7621 ttttccacgc agacggatat attggatttt ctgatttcac gatcgaaggt agccgttatt
     7681 tcgataaagg gttccctagc cgagcgcttg ctatccatct aacgtatatt gatgcttacg
     7741 gcaatatacg cgtgaaacat tttgtctctg acagtaacga ctctgctaaa gaccaagcat
     7801 tgaagtttct tgaagcagga gataaaatga aaaaatggat catgcgtcac catcatcaac
     7861 tcttgattac ttcaggaatg attgaattat tggctcttta ccagcaacaa aaattccctg
     7921 gactgggagt gttgaaaaag tggtcactta tgcatcattt ggaacttatt agtcacctgc
     7981 tagatcatcc aaaagattgg cttaaatatt attcaaaagt tcaggaacta tatgaagtga
     8041 tccaatgatt agataatgta aatgaaaaag gaatagaaaa gaggaaactg gatgtatatt
     8101 cggcaaacaa ggaaagaaga agtagaagaa gtggtagaaa tcattaatgc cgcagcggat
     8161 ttcattgctt cgcaaggctc tcctcaatgg caaaacgggc agaaaccaac aaaagaaacg
     8221 attttgaacg atattgaaag aaaagaaagc tatgtattaa tagtggaaga tcaaattgct
     8281 ggaacagctg cattagtctc aggcgtggat cccgtttaca caaaaataga tggtagttgg
     8341 aaagaatcaa ctggtcctta tttatcgatt catcgtgtcg ctttagcaga aagtactcga
     8401 ggaaaaaaac tagcaaaacc gttcttagaa catttgttga cgattgcagc cagcaaaaat
     8461 atccaagata tccgtatcga tacttatcca gctaatgaac cgatggaaaa gaccatctat
     8521 tctgctggat tcacttatca agggatgatt gaatttcctt ttgaacacgg cgaaagaaaa
     8581 gcatatcaaa taatcatcaa ttgactataa aatcatctga gcaaagataa agacattaac
     8641 actactgaaa aaaacaatca tatgatagcc aagaggttgt aacagaagtg gccagcttca
     8701 aaaaacaaga aagaatttcc gaaaatgctt ctcaaatttt tgtggaattt tagcgtattt
     8761 tacgaaatag ctgctttctg aaactccctt catcgagagg tcgtgacata gcttttgtca
     8821 cgatctctcg gcttatccta cgagtattat tcgatacatt tatatcaata atcctttttt
     8881 tattttatct gcagcttctt ggaacgctcc atcgtttgac acgactaaaa gtgaggggat
     8941 agctttcaaa cgtttcaact gtgctaaatc ttctacataa accgccagtc tggctgaaat
     9001 ctgttcagat gaatctccac gttttttcag gcgcgattgc aatgtttctt tagagatcgt
     9061 aataaagata ggacggacta ccgtcccgaa atactcatat aaatgccaaa aaccatttgc
     9121 tgtcaaaacg gcgtaacaat ttcctactgt cagtttcttt ttaatttctg ctttactgga
     9181 accatattta tgttgagcat attggtccca ctctgcaaac tcatttccct tgatcatctg
     9241 attgaatgta ttgtcagaaa caaaataata atcctcttga tctttttccc caggtcttgg
     9301 tgatcgattc gtgtaagtaa tgatcttttg ttccggctga aaaatagctt ctgcgagtga
     9361 agtttttcca gaaccagaag gaccgataaa tacatagcaa taattcattg tcatttctcc
     9421 tttgatgatt gaacaagtga aaaagctttg gaaaatattt ccaaagcttt taaaagtaac
     9481 tttgcttttt tgtattttat accagcaagc cagtcacaat agcacttaaa aagctgacta
     9541 aagtcgctgt tagcaaaatt ttcaatccgt gttttgcgac aagatttcct ttttcttcat
     9601 ttaatccctt catcgcacca gaaatgatcc cgatagaaga gaagttggca aatgaaacga
     9661 ggaagacaga tataattgct gttgtacgct cagtaaaatg gaaattacca tttgctaatt
     9721 ctgtcatagc aacaaattca tttgtaacca gtttagtcgc catgatacta ccggcatcca
     9781 ctgcttcttt ccatgggatt ccgctgatga aggcaagagg ggcaaagatg taacctagga
     9841 tctcttggaa agtgatgccg aatatcccgt ggaagatagc attgatcatg gcaatcaaag
     9901 caacaaaacc gataagcata gcagcaaccg tgatcgccac atggaaacca tcaagaatgt
     9961 attctcccaa catttggaaa aatgtctgtt ctttgttttc ttcaatgatc agctcatctt
    10021 ctttttcttc taatacatag ggatttacaa ttgaagccag aatataaccg ccaaataagt
    10081 tcaaaacaag ggcagtgatc acatatttag aatcgatcag tgccatataa gatccgacga
    10141 tcgacataga aactgtagac atagccgata cactcatggt gaacaaacgt ttctcagata
    10201 ggaagggtaa ttcctttttt atggaaataa aaacttccga ttgtcctaaa atagcagaag
    10261 ctactccatt ataagattcc aatttgccca tcccgttgat tttacttaat cctagaccaa
    10321 cagctttcat aaataatgga agaatcttga tatagcgtag aataccgata atagcagaaa
    10381 taaatacaat tggcatcaat acggaaagaa agaaaggtgc acttccttta tttgctacac
    10441 cggcaaaaac aaagtcaaca ccttgcccag caaaagcaag aagatgatca aacatttttg
    10501 ccaatacaga aacaaccgct gtaccaaaag ttgtacgtaa taatacgaaa ccaagaacaa
    10561 gctgtaaaac gaacatcaca attagtggtt tcaatttgat tgcttttttg ttactgctga
    10621 tcaaaaaagc aagccctaat gtgacaaata aaccaataat acctaataaa taactcaaat
    10681 aatcactcct attccaaatt ccgttttatt ttacctgttt tgcaaataaa atactaatct
    10741 ttagtgaaat tttcattact tttttagagt gaaacgcatt cattttccat tagaaaataa
    10801 agcgaacaaa ataaaaggtt taaaaagtgt aacgtcttag taaagtctat aaaaaaacga
    10861 aactatcgat taagctaata gtttcgtttt caacatttat aagtaaactt tttctattgg
    10921 taatatagat tttcggaagg gtagacaggt gcgcaggtaa tatcgattcc tagttttttc
    10981 aatgtttgtt catcattttt attgaccatc acagtagagt gggcttgtgc tccctcaagt
    11041 tcagctagtt tatcataagc aacttgagcg attggattcg ttactgcact gattgataaa
    11101 gcgatcaaga cttcattgat gcttagtgca tccaaagagg aatgaagtgt ctttgatttc
    11161 aatccttgta ttgtttcaag aactaatggt gacaataaag gaatgtcatc tgcgatatgg
    11221 gctaaatgtt ttactgcatt taagataact gccgctgacg catccatcaa tgaacttgta
    11281 cgcccggtaa tgatgacttc atctggtaat tcgattgcaa tcacagcaga aggatctttt
    11341 gtaggacttt gcgcttgaat cttatctgca tagtcatggg cagggactac cacgtttcgg
    11401 tcttcaggac gtaaaccgac ttcttccata atcagtttga ttcgattaac tgcttcttcg
    11461 tcgatcaatc cttttttgaa gtcgcattct gtttggaaat aacgacggat gatttcttgt
    11521 ttagaggctt cttggacaac ggtatcatcc acgatcccaa atcctacacg attcacaccc
    11581 atgtcagtag gagattgata aacagattct ttaccagtaa ttttttcaat aatacgtttg
    11641 attacaggaa atgtctcaac atcccgatta tagttcacag ctactttatt gtaggcatca
    11701 aagtggaagg aatcgatcat attgacatct tttagatcga ctgtggctgc ttcataagca
    11761 atgttcagcg gatgtttcaa cggaacattc catactggga aagtttcgaa cttggagtaa
    11821 ccagctgcat gtcctttttg gctttcatga tacagttggt tcaagcaagt agcgagcttt
    11881 ccacttcctg ggccaggagc tgtcactaca acgattggtt tagttgtttc aatatactca
    11941 ttttttccaa aaccatcttc tgagacgatt ttttctacgt tgactggata gtcttcgatt
    12001 tctgagtgtt tatagacctt gatgtttcgt ctttctagtt tattgataaa gactttcgtg
    12061 gcaggctgtc cactatagcg agtgataacg acactgttga ttaataagcc ataaccacgt
    12121 aattcatcga ttaaccgcaa gatatccata tcataagtaa tcccataatc accacggatc
    12181 ttattacgtt caatatctcc agcatagacg caaatcagta tttcagcttg atctttcaat
    12241 ttttgcagca atttgatttt cgcatcttct tcaaatcctg gaagtacacg tttcgcatgc
    12301 ttgtcgtcaa ctaacttccc accaaattct aaatataatt tgtcatagtg gttcactcgt
    12361 tccaaaatat acgctgactg ctcttcaata tatttttctg aatcaaaacc aatttttttc
    12421 actaggttcc ctccttaagt actaaagcat tttttcattt ttttgaggat tcgtcaactg
    12481 gaagagcgaa attcctcaaa aaaacaaaga aaatggttta aaccaacttg tctagatagt
    12541 tattcattgg tatgatagtt tttgataagg aaggtgctac atgaaaaaaa gacagaaaaa
    12601 gaaaaacgca tataaacact atatccgttc gatttttacc ggttatgaaa gaatgcttga
    12661 agatcccgaa ttggaacaat tgacgtttac ttatctaaac gaagaaacgc agctaactcg
    12721 tgatgagcat cagcgcattc atttcacaac aagagatctg cctagtaaat aaaaaataag
    12781 ataaaggtca tcggattcga ttctgtccta tcagatggaa agactagttg atcgaaaaaa
    12841 aggctgtacc aaattttggt gcagcctgtt ttatggagca ttgcccgctc ttttttataa
    12901 caatttttta cagaaaatgg tactattgaa gtattaataa gtgaaaaaca gatgagtaag
    12961 aggaggcaag tagtatgaaa gagccagata caaatgcaaa ttatgagcca gacgaactag
    13021 aggagacgaa cgcggatcag gatacaggac aagaatcgtc ttctttttac gatatcaaag
    13081 aaaaagcaag catgaatctt tcccaattat tagaagactt acaggctttt gaaaaagctg
    13141 tccgcgaaga agatatccct gagatctacc gtttatacaa tggccgattg aatgaagaat
    13201 taaaaagaag ctcaaatgaa aatcacgaga tcgatcaatt gctgatgcgt aagatccatg
    13261 atcgtttttt acaggaattt ccttttatgg aacaagtaga aaacatctcg ccaacgatga
    13321 gctattacaa aatcggcact tattaccatg atcggcccac ggtcggtatt gatgcaagtc
    13381 tgccagaaat ttttgttttg cctaagatcg atgaagagtg ggagaaatat tcccaaccgg
    13441 agtcaacgga ctatgacaaa aaaatcaatg agctagacgc aaaggtgatc actgctcaga
    13501 cagaaattga acgtttagat gaacaaataa aagaaatcaa tcgacaaatg actgatttga
    13561 acgacaataa aggattcttg aatcgtaaaa aaatcgagga agaaattcaa gaattagaga
    13621 agaagaagca agtactatct aatgaaaaat taggctggct tccttatatt gagacgcctg
    13681 aaacaatcca gcagcaaaaa gaagcattga agcaagaagc aagagcagac cagcttcgtg
    13741 cagccatcgt agaaaaagaa caaaggcaaa tcagacgcta tttcggtagc aaagagggat
    13801 tcggtcaagc aatccatgaa ttcttgatga attatcttgg caatgagaat cctaataatc
    13861 aatctaatga aggaggttcc gagtatgaat gaacacgatg aagcagaatg gacaaaaaat
    13921 gaagaacaaa cagaagatca tgaagaaacg aacacttcat tggaagaaca aacaagtaat
    13981 cctctggatg acacagaaga aatccctatg ctagaggaaa caaaaataca tgaaaaagaa
    14041 aaagtaactc cgacgaatac gaatactgca gaaaacaccc atgcttacga aataactgaa
    14101 aatcccgggt atttagaagg aaaagagcaa gatcatcaag atatcgtcag tttgattgaa
    14161 acagcggaag cagaattagc ggatttacgt atgagaaaag atttgatcga atcagatttt
    14221 ccacaattat tagaatcata tgatcgtttt atattgaatg aagaaccaat ctccacgatc
    14281 ggaaagacaa gcctgatcga atacttcacg tatgaattac tgaaaccgtt gaatgatatt
    14341 ggtctggaac ggtcaaattc agcttatgac acatggaaaa caagacattt ttcgatcaat
    14401 tatacgttga atggacaaaa cgaattagtc ttttcctttg tattaccgac catcgatcaa
    14461 cgataccaag tggaatcgat gagtctccta aacgtatcac cagagacaat ggaaatcaat
    14521 gtccaagatg accgggtgct ttctttgatc cgacactggt cagtggatcg agtattctct
    14581 gcagggcaga tcacgatatt caatcacaaa ttgaatcaat tattagccca tgcaagaaca
    14641 cttggtttta ccgttaatca gacattacta gacaatacga agccacttcg tttgaatctt
    14701 cagagcgaat ttgaattgac gaatgaagta ttggatgata tttttatcgt ggcaatgaaa
    14761 aatccatcct acgatatgga aaagatcaac gaaactactt atcaagtacg attagataaa
    14821 ggacagtctt taacgataac aacaaacgaa aaagatcaaa cagtcttgtc gatctcatct
    14881 ggagactacc cacgatctgt cattgatttc tttatcaatt acgaattctt ggtcccatta
    14941 atggtgagaa agtcctgatt ggataagttg gattaccaga tgtcattcag ataattctgt
    15001 tccaaaggac ttgcggcagt tatccagaat aattgtcaca agtcttttct gtatgtacta
    15061 aatggacgtg aataacttgc tgatgaagga gggatttcat taggaatgtc cacaaataaa
    15121 atagcacagc ttagcttatt gtctgctgct tgtgtagcag gtaggatcgc ttttcaattt
    15181 attccgaatt tccagccaat gactgctatt tttttattta tagtacttta cttaagctta
    15241 aaagatgcgt taattgtcat gagtctttct attgcgatca gcagttttta ttttggtgtt
    15301 ggaccatggg tcatcggcca atggatcagc tatactgttg ttctgagttt gttttcaatc
    15361 gtctgcttga gaaaaacagt gcaaaggaat ctatggttaa agggagtctg tttttttctg
    15421 gcgggcatgg tttacggaat aggtatgacc gtttttgata cgctgttata tcgtttgcct
    15481 caaccttgga tctattacct tcaaggggtg tcgtttgatt tgatgcacag tataggcaat
    15541 gttgtgttct ttcttgtttt tctgccagtc gtcaaacgtt tttacaatca ttcaggagga
    15601 aaaaatgaaa aaaataattt atagtttgct tgcaatgagt gtcagtatac tcattttgac
    15661 aagttgcagt acaacctata cacaatcggc ttccaaccaa aaggaggaag taaaaacatc
    15721 gcaaaaagca acaatcacgt tacaagaaaa tggtcaaaac ttttcggaaa aagaagtggt
    15781 cttcaaaaaa ggcgatgatt tactgagtat tttgaaacga aattttgaag tcaaagaaga
    15841 taacggcttc atcacttcgc ttgaagggca ctcacaggat gagaaaaatc aactctattg
    15901 gatgtttact gtggacggga aaagtgctac tactggtgcc aaagagatca aattgaatga
    15961 tggacaatcg gtcattttca atttgtctaa actataagtt tcataaaaaa ctgttaaagg
    16021 gcgaatattg ccataattca gtgagttcag ttgatgaaag aaggaaaata acatggaaaa
    16081 ttttaaaaaa agcggaatgt tttccgtaat tgctgctcta ggggctaata ttctagttgc
    16141 tatcagcaaa tttgtcggct atgcaatcag tggcagtgcc gccatgctaa acgaaagcat
    16201 ccacagtatc gttgattgca gcaatcagat tttgctgtta ttcggtgata aacaagccaa
    16261 taaaggacag agcgagttgc atcaatttgg tgaaggacga gcaaaatact ttttcagtac
    16321 aatcgtcgca atgatgcttt tcttcggcgg tggggcactt ggggtgatgg aagcttttga
    16381 aaagttgacg catccatccc atgaagtggg taatccgatc attgttatag caatactgtt
    16441 atttggtttg gtaatcgaag gaagttcgtt acgcgtggca atgaaagaaa tcaaagaatt
    16501 gaatactgaa aaactttcca cgatgcgctt tttgcgcgaa agtcgacaca gtgaaatact
    16561 gattattttt acggaagact tgtgtgctgt aatcggtttg gtcttggctt tagcaggaac
    16621 aatattgact tatgcaaccg ggattgctgc atttgatgcg atcagcggat tgctgatcgg
    16681 tttcttgctg atgggagccg ccattttcct agcaaaagaa ttttatagtc tgatcatcgg
    16741 tgaaagcgtg acagcaagcg atttatcaaa aatcaagtta gcttttgaac gtcctgagat
    16801 cagtcggctg atcgatataa aaacagttca tttaagtcca acggagattt tagttgcagc
    16861 aaaagcagat atcgttggta acaaagagaa tgaagcttac tcggtcatca atgatattga
    16921 aaaaaatatg cgtcagtctc ttcctgacaa gaagatgtat atatacattg aaacagataa
    16981 atatgaccca aattattctc gtaaataaaa cgtttattca tgaattgaag caaaaatgag
    17041 aaaaatataa tcttgttttt aaataaaacg gctacaattt agcgaattta tgttacaatg
    17101 agtccgctgt ttatttgttg taattaaagg agatatttta atgaacaaaa agaaaagtgc
    17161 gccatggctt caagctttgc atgcagtgat gccactttgt ataagctata taccagtagg
    17221 attagcttgc ggagtattgt tgcaaaaagt tggatttgat cctctcttat caggactgtt
    17281 atcgattctg gtcttttccg gtggcgcgca gtttttagtt gcatctatgc ttacgacgca
    17341 agcatcattt gcaacgacat tattgatggt tttcttttta gaattacgct atacattatt
    17401 aggagcaagt cttgccggtt ttatgaaaaa agaaaagcgg acgtttttgg ctgtcttttc
    17461 tcaatcactg aatgatgaaa actatgcggt gaactactta aagttttcaa ctgacccttc
    17521 ctggaataaa agaaaggctt tatatgtcaa ttggttctca atgactgcat gggccggtag
    17581 caatatgatc ggtaattttt tcggctcggt gattcgagta gatgctgacc ttgtccattt
    17641 tgctttgacg gccatgttca ttttcatgtt tatcatgcag atgaaaagcg cactactgat
    17701 ctttacaggt ttattctcag gcgtattagg ggtcgtattc atggtattat tccaaaatac
    17761 tttcggattg attgcagcaa cagtcattgc ttcatttgcc ggatttatgc tggagaaggc
    17821 attcaaaaaa gaaaaagcta agaaactaag agaccgcggt aaagatgtca atgagccgct
    17881 cttcaacttc ccggaacagg aggccaatca ccatgactaa actatatttg ctacttttag
    17941 ttgcttgtct gttcatcgtg gcatatatcc cgcgcttgtt cccgatgctt tattttactc
    18001 atcgaaaagt gccatcctgg ttcagtgact ggatgaaata tgtaccggtg gcattatttg
    18061 cggcgttagc ttttaaagat gttttcatta ctcatgaaca tctggatatt gcttggaata
    18121 tcaaaatagc tgcaatgatt ctagtagcag gcgtggctta caaaacacgt tcgatggcgt
    18181 tgtcagtttt gacaggactt gcgtctgtct ttttgctgtc tatgctttaa actgttttat
    18241 tttattaaaa acagagattg cgacataagt tgttcaaact gatctatccg aactgcattt
    18301 gcaacagtca attctggatg caagtttatt cgtagggata aaaaagatta gtgttggctt
    18361 atgatgcaag ctctttttta ttttaggaat tagagaggga tttgtccttc tatgattttt
    18421 tgctataata gggaagatgt ttattttatg aaagaatagt tgagggaatt taaatgaata
    18481 aaaaattgat gcaaggaaca ttttggctaa cctttgctaa tcttctatgt aaagttttag
    18541 gggtagtcta tttgattccc tggctaagta tgatggggaa caatcaagat ggtatgcttg
    18601 ctacgacatt gtataatgtt ggctatcttc cttatggatt gttcctgatg cttggtacag
    18661 tcggatttcc aaatgcgatt gcaaaaaaag tagctgtagc cacaaaagaa ggagataacg
    18721 ctgcttgtcg gctgattttt agaagtacga tcaatatcat gtttgtcatc ggtatcgcct
    18781 ctgctgcact gatgtattta tttgctcctt tactagccgg aatcagtccg attgctaacg
    18841 ttaataatgg gatactagct atcagaagtt tatgcccatc tttgattgct atcccaattc
    18901 ttagtgcaat gagaggatat ttccaaggaa aaaatgatct gcggccttat ggaacttctt
    18961 tgattatcga acaggctgtg cgagtgatcg ttatcttggc tggtacttat tacttgcgcg
    19021 tattgactga cggaaccata ttagaagctg tattgatcag tacagtcgct tctttcttcg
    19081 gtgggttagc tgcgattatc catatgtata tcgtcggacg cagaaaagac ttcttcgaac
    19141 ttaaagattt tttgatttcc agccgttatt tcgaaagaga aaaccgatct gcctctgtct
    19201 ctatcattcg ggaaacacta ccgtttattt ttgtcggctc agtcattact atcgttcaaa
    19261 tgatcgacca agtaacgatg aaaccactgc ttcacttttt ccgtccagag atcgcagatc
    19321 agcaactgga attcttattc agccgtgctt ctgtcaatcc aaataaattg acattgatcc
    19381 tgatctccat ggtaggaaca gtagctataa gcagcttgcc aatattaagc acgatgaaga
    19441 aaaaagatcg gatacaaatc gaaaaaacag taggagatag tttttcgatt gcgttattga
    19501 ttcttcttcc ttcattgact ggaatgtctt tattagctgg accactatac acattgtttt
    19561 ttggctatga tcctgaaagt gtcggatatt tccaaatggc tttgctagct tctttgtttt
    19621 tctctttatt cacgatccta tctacgatgc ttcaatcttt gaatcaccat cgttttgcga
    19681 tccgattaac tgtagaagca attatcctga aagtcatctt ccaagtaatc ggattaggat
    19741 tagttggcgg atacgggatg agcttatcaa atggcttagc attcggtatt gtctttgttc
    19801 gcggctatca ctttatgtgc aaagaatacc gaatagcacc tttagcaaag atcagcaatt
    19861 ttttcttaaa aactttccgc tccaccctga ttatgcttgc agtatgtttt gccgttttct
    19921 ttttgctgaa tcagcgattg tcaatggaat caaaaagcta tgcaatgatt tattgtgtgg
    19981 ctgtaggaag tattggcggc ttagtatttt tattttctca attcggaaaa aatgggtttc
    20041 gaatgttgaa aaatgttaaa catcatagca gaagcaaaga ataggttaac taatcgtttt
    20101 ttgctgtcac ttgaaaaacg gcaactcgta tgattacgct tgtcgttttt ctattttcca
    20161 attttagttt catatctaat cttacttatg atatagttat aaggtctgga aaaattcttt
    20221 gaaacgagga aattaaacac atgaaacttg cagtagttac agatagttcg gcatatctgc
    20281 cggaacgtat caagaaccat cccgacttat tcgttattcc aatccctttg attatggatg
    20341 ggaaaattta taacgaagga atcgatatcg aagcggatga atattatgga cttttaaaaa
    20401 acagtaaaga ttttcctact acttcacaac ctgtcgtagg ggaagttttg ggtttatatg
    20461 aggaattgaa agagaaaggg tatgacacga ttttaagtat ccatctttct tcagggattt
    20521 ctggctttgt caacacatta tttgcgatga aagatgacat cagcggagta acggtcattc
    20581 cttatgactc taagatcact agtatgccga tgggacacat ggtagaagct gccttagact
    20641 taaatgatga aggtcagtcc cttgatgaaa tacttgcaca tatcgatcga atccgagata
    20701 atacctatgc ttatctgatt gtagatgatt tgaacaattt agtacgagga ggacgtttga
    20761 caaatggtgc agcgctgatt ggcagcttat taaaaatcaa accgatcctg acattttctg
    20821 aagggaaaat tgttttattc gaaaaaatcc gttcaagtaa aaaagcattt gctcgagctg
    20881 aagaaattat tggtagaaga aataacgaaa tacaaccgcc agtcaaactt tacgtgatac
    20941 atgcaaataa tttagaagta gcgattgcgg agaaagagaa attgcagaaa aaatatccaa
    21001 atgcagaaat cgaaattggt catttcggac cagtcattgg tacacattta ggtgaaaaag
    21061 ccatcggcat tgccatttca gcgcaataat tccttttatt caaaaaacat accaaaaata
    21121 t
//
LOCUS       DACGEU010000047        20946 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.047, whole genome shotgun sequence.
ACCESSION   DACGEU010000047 DACGEU010000000
VERSION     DACGEU010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20946)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20946)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20946
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.047"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            591..1280
                     /locus_tag="IXR40_001635"
     CDS             591..1280
                     /locus_tag="IXR40_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4361489.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1267..2475
                     /locus_tag="IXR40_001636"
     CDS             1267..2475
                     /locus_tag="IXR40_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAQ4361490.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2769..4040
                     /gene="serS"
                     /locus_tag="IXR40_001637"
     CDS             2769..4040
                     /gene="serS"
                     /locus_tag="IXR40_001637"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HAQ4361491.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4589..6073)
                     /gene="guaB"
                     /locus_tag="IXR40_001638"
     CDS             complement(4589..6073)
                     /gene="guaB"
                     /locus_tag="IXR40_001638"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HAQ4361492.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6578..7273)
                     /locus_tag="IXR40_001639"
     CDS             complement(6578..7273)
                     /locus_tag="IXR40_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HAQ4361493.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7363..8463)
                     /gene="ychF"
                     /locus_tag="IXR40_001640"
     CDS             complement(7363..8463)
                     /gene="ychF"
                     /locus_tag="IXR40_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HAQ4361494.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8472..8663)
                     /locus_tag="IXR40_001641"
     CDS             complement(8472..8663)
                     /locus_tag="IXR40_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HAQ4361495.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8684..9574)
                     /locus_tag="IXR40_001642"
     CDS             complement(8684..9574)
                     /locus_tag="IXR40_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HAQ4361496.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9561..10328)
                     /locus_tag="IXR40_001643"
     CDS             complement(9561..10328)
                     /locus_tag="IXR40_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAQ4361497.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10340..11053)
                     /gene="rsmG"
                     /locus_tag="IXR40_001644"
     CDS             complement(10340..11053)
                     /gene="rsmG"
                     /locus_tag="IXR40_001644"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HAQ4361498.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11285..13186)
                     /gene="mnmG"
                     /locus_tag="IXR40_001645"
     CDS             complement(11285..13186)
                     /gene="mnmG"
                     /locus_tag="IXR40_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HAQ4361499.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(13203..14600)
                     /gene="mnmE"
                     /locus_tag="IXR40_001646"
     CDS             complement(13203..14600)
                     /gene="mnmE"
                     /locus_tag="IXR40_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HAQ4361500.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            14944..15282
                     /locus_tag="IXR40_001647"
     CDS             14944..15282
                     /locus_tag="IXR40_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361501.1"
                     /translation="MSPFRSAALEEESDPRINDVVLSTGNINQKYIVRDIVFVVECLE
                     ADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQKKRDGKYFLELFAYGT
                     VIQFIQTTIG"
     gene            complement(15450..16208)
                     /locus_tag="IXR40_001648"
     CDS             complement(15450..16208)
                     /locus_tag="IXR40_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HAQ4361502.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(16226..17044)
                     /locus_tag="IXR40_001649"
     CDS             complement(16226..17044)
                     /locus_tag="IXR40_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HAQ4361503.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(17041..17397)
                     /gene="rnpA"
                     /locus_tag="IXR40_001650"
     CDS             complement(17041..17397)
                     /gene="rnpA"
                     /locus_tag="IXR40_001650"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HAQ4361504.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17515..17649)
                     /gene="rpmH"
                     /locus_tag="IXR40_001651"
     CDS             complement(17515..17649)
                     /gene="rpmH"
                     /locus_tag="IXR40_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HAQ4361505.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            18173..19507
                     /gene="dnaA"
                     /locus_tag="IXR40_001652"
     CDS             18173..19507
                     /gene="dnaA"
                     /locus_tag="IXR40_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HAQ4361506.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDIKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19705..20835
                     /gene="dnaN"
                     /locus_tag="IXR40_001653"
     CDS             19705..20835
                     /gene="dnaN"
                     /locus_tag="IXR40_001653"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HAQ4361507.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
BASE COUNT         5985 a         4259 c         3839 g         6863 t
ORIGIN      
        1 ggagtgtttc ccgattcgtt tttggctgcc gtagcaactt ttatatcata tcagagagac
       61 aagtaattgt caactctttt ttaaaagttt tttcgatttc gtttttcgaa atcttccagc
      121 aactcattta tcataactta tcgtttgtta tttgtcaaga acttttttga agtttttttc
      181 gatagaatca agcttcgcaa gtggttcttt tttaacgact cagttatctt atcatgtcat
      241 ttccaacatg tcaacaactt attttttatt atttaataag ttattggtgt tcttttgaac
      301 aaataataat atatcaacat cacatgtgaa agtcaataag aaaatgctta tttatcaaca
      361 tttctagctt acatgatcat tggttagttc tggtcctttt tcgttcgtct ttataactcc
      421 gagagacgta aaatcctttt gttttcagtt taatgttcat gttcttgtct tattcacacc
      481 aactagatgt ctcaccttct aaaattttcc ttaacaaagt gctgctttta tctatttctg
      541 cttttttttg ctagaataat agtaacaata tgactctgga ggatttattt atgaaaattt
      601 tgattgctga cgatgataaa gaaatcgttg aattattaag tatctatgtt cacaatgagg
      661 ggtatgaagc agtaaaggct tatgatggga aagaagcatt atctaaaatc agaacaatcc
      721 ctgatattga attacttatt ttagatatca tgatgcctga gatggatggg atgcaagtag
      781 tgaaagagct acgaaaagaa tcccaaatac caatcattat gctgacagca aaaactactg
      841 atatggataa gatcaaagga ctggtcgctg gtgcagatga ttatgtgacc aagccattta
      901 atccgttaga agtaatggct agagtaaagt ctttattacg gcgtacaaaa atgcagattg
      961 ccccagatca gcctgatgta ttagaagtaa atgcattaat catcaataaa gactctcatg
     1021 aagttaaaac aatcgatggg aaagaaatcc agttaacagc tttggaattc ggtatcctct
     1081 acttgcttgc tagtcatcct aatcgagtat ttagcgcgga tgaaattttt gagcgtgttt
     1141 ggaaacaaga aagtattgtc tctgctaaaa ctgtcatggt tcacgttagt catttaagag
     1201 ataagattga agaagcaact ggtggtgaaa aagtcattca aaccgtttgg ggagtgggct
     1261 ataaaattga cgcaagatag taaacgagca actgaaaaac gccgtcggat caatttgact
     1321 tcaaaagaaa tcagcgaatt gttagcggaa ggaatcatca cgattatcct tttgcttcta
     1381 ttaaatgttt ctattctggt tgttatcagt tcggtgatca acagttcacc ttctttgacg
     1441 aatgcgattt gggattcaaa gaatattttt gcagaacgat tgaacactga tttgttctgg
     1501 aacggccgga attttattat tccctttttc tttctattag atattggtgt tttgtattgg
     1561 cgcttgattc gaagatatcg ccaaatgcaa ttgcggcata tcatcagcga acttcactac
     1621 atcgcaaacg gaaattatga tcatcgtatc ccttttgaac tgagtggtga cttaagccga
     1681 gtggtaacaa gtatcaatgg attggtggat agtaccgtag cagcgattga agacgaacgt
     1741 aaaatcgaaa aatcaaaaga tgaattgatc acgaatgtca gtcatgatat ccgtacccca
     1801 ctcacgtcca tcattggata cctaggactg atagaagatg gccagtatca ctcagaagaa
     1861 gatcttttaa agtatacgca tactgcttat atcaaagcaa agcagatgaa atctttagtg
     1921 gacgacttat ttgaatacac taaggtacgc cagcctgctg tcccggtgaa tttttctgcc
     1981 tttgacatga tccagttgat cgaacagtta gcagctgatt ttgagttgga agcttctaaa
     2041 aaaaatatcc aaatacttgt tcaatcaaaa gtagactccc ttatcatgga tggcgatacc
     2101 gaaaaacttg tacgtgtctt caataatctt ttgacgaatg cgttgaaata cggaaaagga
     2161 gcaacgaaga tcgtaatcga agtagaacgt atcggttcag aagttgttgc aacagtcaaa
     2221 aataacggag caatgatccc acaacaggca atcgataatc tattcgaccg tttttatcgt
     2281 gtagaagaat ctcgttcaca agcaactgga ggaactggac ttggtttagc aatcgctcaa
     2341 agcattgtgg ctttgcacgg cggatacatt tatgcaaaat cagataagca atggacttct
     2401 ttcatcatgc accttccaat caagaaaaat gaaaaattac ctattgatac acaggaagtt
     2461 attgacgaaa gctgaaatat tcgctattct tattacaatt attagaataa atgaaaaaca
     2521 cagaacccag tacactttat tctttttcag agagctgatg gcaggtgtaa atcagcaaag
     2581 gataatttgg aagttccagt tcgtttacgt gccctttcga aataagaaag gtcggttcaa
     2641 cagccgttat gtgttcaaca agtgcagctg acgctgaact tgggtggtac cgcgaatttc
     2701 agactgattc gtcccaagaa taatgggatg gatcagtctt tttttatttt caaaaaggag
     2761 gaaatcatat gttagatgta aaaatgatgc gacaaaatat tgaagaagta caagaaaaat
     2821 tgatgactcg gggcgtaaaa aaagaaacat tagctgaatt catggaacta gatgaaaatc
     2881 gtcgtaagct actagtcaaa agtgaagaat taaaaaaata tcgaaatgat gtttctgctg
     2941 agatcgccca attgaagcgt gcaaaagaag atgcttctgc taaaatcgct gaaatgaaag
     3001 aagtcggtgg caacatcaaa gcattggata ctgaaattgc tgaagtggat gaaaaattga
     3061 aacaaattgc aactactttg ccaaaccttc cccatgattc tgtgccagtt ggaacagatg
     3121 aagaggacaa tgtagaaatc cgtcgttgga gcgaaccacg tacatttgct tttgaaccaa
     3181 aaccacactg ggaaattgca gaaaatcttg atattttaga ttttgaacgt ggcgcaaaag
     3241 tagccggtag ccgttttgtc tattacaaag gattaggtgc tcgattagaa cgtgctgtct
     3301 acaacttcat gcttgatcag catatttacg aacacggcta tactgaaatg atcactcctt
     3361 atatcgtcaa cagtaaagcg atgtttggta cgggacaatt tccaaaattc aaagaagatg
     3421 ttttccaatt ggagaatact gatctaacat taatcccaac agctgaagta ccattaacta
     3481 actattataa tgatgaaatt ttagatggtg cagatttacc tatttatttc actgcactaa
     3541 gccctgcttt tcgttctgaa gccggaagtg ctggtcggga tacacgagga ctgattcgtc
     3601 ttcaccaatt caataaagta gaaatggtca aattttcgga tgtagagcat tcttacgaag
     3661 aattggaaaa aatgacagct gatgcagaag atatcttgaa aaaattgcat ttgccttatc
     3721 gtgtgatggc cttatcaact ggagacatgg gcttttctgc agctaaaact tatgacttag
     3781 aagtatggat acctgcacaa gatacttatc gtgaaatcag ttcttgttct aactgtgaag
     3841 atttccaagc acgccgcgca atgatccgtt atcgcgataa tgatggaaaa atccactata
     3901 ctcatactct gaatggttca ggacttgcag ttggccgtac agtagctgcc attttggaaa
     3961 actaccaaaa tgaagatggt tctgtcacag ttccagaagc gctcgttcct tatatgggga
     4021 atctgaaagt tattaaataa agaggctgtg aaaaagccgc ttagtttcga gtattaagaa
     4081 aaattttgtg aaaatggctt tccacatttt tgcataaatt ggacttaata ccgagaaact
     4141 ggcttttgaa caccatttat cgagaggttg tgaaatcagc gaattaacct gagtattaga
     4201 gaaaaaaatg gaaaaatagt ccctcatatt ttaccgtttg ttgaactaat accgagggtc
     4261 agctgattga acaccgttta gtggagaggt cgtaagccta ccccccagct cctagttaca
     4321 aggacaaatt caaaaaacag ctcttcatat tttatgaatg ttgtacttgt gattcggagg
     4381 tggcaaggga acactgttta ttcaaaaaga ggctgggaca gaagcgttta actccaagaa
     4441 ataagaagaa attcacgaaa attgcttttc aaatttttgt gaatttcttc ttatttccga
     4501 aggagttgct tctacttccg ccgtttatac gtgtttagag cgtgagacaa aagtgttctt
     4561 tacttttgtc ccacgctctt taatgttttt aagattcaac tgaatagttt ggtgcttctt
     4621 ttgtgatttg tacatcatga gggtgtgatt cttttaatcc actgccgctc atttggataa
     4681 attgcgcttc atcacgtaat tgctgtagat tggctgcccc aacataaccc attcctgaac
     4741 gcaaaccgcc gatcatttgg aaaataatat ctgcaacact tcctttataa gcaacccgac
     4801 cttcgattcc ttctggtact aatttatttg cttcattgac actaccttgg aagtaacggt
     4861 cttttgaacc tttttccatc gcgcctaatg agcccatacc tcggtatgtt ttgaatcgac
     4921 gtccttggaa gatttcgaat tcacctggtg attcatctgt ccctgccaac atacttccta
     4981 gcatcactgc atgtccgccg gcagctaatg ctttgacgat gtcaccagaa tatttgatcc
     5041 ctccgtctgc aataatcgct ttgccatatt gacgagcaac tgatgctgca tcataaatag
     5101 ctgtgagctg aggtacacct acaccggcta ccacacgtgt cgtacaaatc gatcctggtc
     5161 cgataccaac ttttacgaca tctacacctg catcatataa agcttttgtc gcttcagccg
     5221 tcgcaacgtt tcctgcaatc aatgttgcat ctgcaaaagt tgaacggatt tcttgaattt
     5281 ttcggatcac acctgcacta tgtccatgag ctgtatcgat gatgattgca tctgcccctg
     5341 cttctaataa agcattcgca cgctcaaatg tatcgcttgt tacaccaacg gctgctgcta
     5401 caagcaatcg accatgttca tcttttgctg catttggaaa ttcgatcact ttctcgatgt
     5461 ctttgatcgt gatcaatccg cttaaacgac cttcgttatc tacgattggt aatttttcga
     5521 ttttatgttt ttgcaaaatc ttttctgcat cttttagaga ggtacctact ggggcagtca
     5581 ctaagttgtc ttttgtcatc acatcagcaa tcggcatgtg ataatctgtt acaaaacgca
     5641 tgtcgcggtt tgtaattatc cctaccaatt ttctgttttc aagtgtttca acgattggca
     5701 caccactgat acgatatttg ctcatcaatt cttctgcgtc tgctacaaga tgctgcggcg
     5761 ttaagaagaa cggatcaatg attacgccac tttcagaacg tttgactttt cttacttcat
     5821 ccgcttgctg gctgatcgtc atgtttttat ggatcacacc tagtccgcct tgtcttgcca
     5881 tagcaatggc catcttgctg tcggtaacag tatccatact tgcactgatg attggaatat
     5941 tcaacttaat atttttagct aattgtacgc tcatatccac ttcgtttggt aacacgtgac
     6001 tttctgctgg tatcaataag acatcatcaa aagtaaatcc ttttttcgtg aactttgttt
     6061 cccagttgga catttttagt accactcctc taatttagtt tatctattaa aataattgat
     6121 tttttcattt aagtcaatga tctacttgga atcaagttag ctttctcata gaataccaat
     6181 ataaagcgtt tacatctgtg tgtattaaaa gagattgtaa aaaagctgtc ctgcatcaag
     6241 taataagaac agccaatcaa aaacagcttc tcatgttttt gaattggttg ggtttattac
     6301 cgcagatgca aacttttgaa caccgtttag tggagaggct gtgaaaaagc tgcttagttt
     6361 cgagtagtaa gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa attggactta
     6421 ataccgagaa actggctttt gaacaccgtt tatcgtaaaa agggactgtg acaagacttt
     6481 tgtcacagtc ccttactatt atttaactat ggataaacaa aatgaggttc tttactaccc
     6541 ctagatatct agcaaaatag ctgatctttt tgctagttta tcttcttggg acggataaac
     6601 ttccaataat cccgtatttt ttcttcaagt agtaacggat tgctaaagca gttgccccga
     6661 taatgataac tactactgga tctaatactg gattgataac tggtggcaat agtgttgtcg
     6721 cagaaaacag tacgacccaa agaagtgtcg ttccacctag gataagcaat gtcttaccca
     6781 ttcctggttt cttgcttcga tctgctccgg gatattcata ttgatagatg tatttgtaca
     6841 tcatataaaa gacccagcca ccgattgcag aacctagaac gagtgtagaa aagccataag
     6901 ctggcgttgt tccacgtgaa aacaatccgg taatcgcaat catgatactt aatagaccaa
     6961 gcaacagcaa cgtattatct aaccacatca ataaaggggt ggatgaattt tttacttctg
     7021 ctggcttatt gatgattgct tccgttcttt cagagactgt cccaaacaat tgacgggctg
     7081 ttcttccgcc tttttgttct gcaactaaag taggcagaat gtcatgaagg gcttttactt
     7141 tttcttcttc agacaaattc gctgcttcta aagatttttt caaatcaaaa atgtactgtt
     7201 gatttctttt ggttaatttt gtttctaaac tattgttttc ttttacgatt gctcgtaatt
     7261 gttctggttc cattatctaa tagtcctcct tagccgttcc ttttctcaac ggtcgtcaca
     7321 aaagacattc taccatattc tacagctagt ttgatagccc ttttacacat taaagcggaa
     7381 taacattacg tcgccgtctt gtacgacata atcttttcct tctaatcgaa cacgtccagc
     7441 ttcttttgct gcatgcatgt ttccgtaatg atccaagtct tcaaaagaga cagtttctgc
     7501 acggataaat ccgcgttcga aatctgaatg gatgattcct gctgcttgtg gtgctttgat
     7561 tccttttttg aatgtccaag cacgtacttc ttgttcccca gcagtaaagt aagtagctaa
     7621 gcctaacaaa tcataagcag cacggatcaa ctgatccaaa cctgattctt cgattcctaa
     7681 agcttctaaa aattccgctt tgtcttcttc atctaattct gcgatttctt cttctgcacg
     7741 agcactgacc acgatcactt ctgcattttc ttctgcagca aagttgcgca cttcttgtac
     7801 ataatgattc gcgtctgcat ctgctacgtc atcttctgag acattggcta cataaagaat
     7861 tggttttgtc gtcaataaaa atagtgattt aacgattttt tgttcttctt cagtaaattc
     7921 gatcgttcgg gcagattttc cttcttccag tacaggtttg attttatcca gtacagctag
     7981 ttctgccact gcatctttat ctttggtttt agcaactttt gctacacgag tatagcgttt
     8041 gttgatagat tctaagtctg ctaacactag ttccaagttg atcgtatcaa tatcttctag
     8101 tggatcaaca cgtccttcta cgtgagtaat attatcatca tcaaaacagc gaacaacgtg
     8161 acaaatagcg tctacttggc ggatatggct taagaattga tttcccaaac cttctccttt
     8221 acttgcgcct tttacgattc cagcaatatc tgtaaattca aaagtcgtcg gaacagtttt
     8281 tttcggatgt acaagttctg ttaagcgttg caaacgccag tcaggtactt ctaccatccc
     8341 tacgttgggg tcgatcgtcg caaagggata gtttgctgct tctgctcctg cttttgtgat
     8401 cgcattaaac aaagttgatt ttcctacgtt gggcaaccca acaattccag cagtcaatgc
     8461 cataaattta ttcactcttt ctctgcattt ttttcaatta ctttttttaa tttcttttca
     8521 aaatctcgac gggtcatcat gacgatatgt ccgcaattca tacatctgat tttgatatct
     8581 gcgcccattc gaatgacttc ccagcgattc gtctggcaag cgtgaggttt tttcatttca
     8641 acgatatcgt gcaagtcgta cataaaaata gcctcctttt tgtttattct tcatcaaatt
     8701 gaatattcaa gatatcaaga attcgagtca aatctttttg agaaagatat tcaatctcga
     8761 tcttaccttt cccatttttt tcttggatag ctacacttgt accaaattta tccatcaaac
     8821 gatcttcgct ttctcggata taatatggtt tttcctttgc tagccttggg atttttttct
     8881 tttcttttcc atcattttga tttaactcag aaacaagctg ttccagttgg cggacagtta
     8941 aattttcagt tactgcacga ttggctaatt tcaagatcaa tgttttattt tttaaaccta
     9001 acagcgtacg ggcttgtccc atagataaac gctgatcttg taccatttcc ttgacaagat
     9061 ccggtaaaga aagcaagcgc aaataattgg cgatataagg tctgctcttt cctaaacgac
     9121 tagctacttc tgcttgtgtt agtttcaggt ttttcatcag catctcatat gcttctgctt
     9181 cttctaacgg attcagatct tctcgctgca agttttccag cactgctact tgcatcatcg
     9241 cttcttcgtc aaagtctcta acgatagcag ggatcgtttc tttttcagct agtttggacg
     9301 ctcgaaaacg tcgctcccct gcaataatct catatccttt tactgcggaa cggcgtacga
     9361 tgatgggttg aaagacacct gattgttcaa tagaattagc tagttcctgc aaagatactt
     9421 cttcaaatgt tttacggggc tgatacggat ttggtcgcag ctcattcaat ggtagctgga
     9481 caacggtatc atcttttaca tccaccgtct ctaagttttc taaatcttga aacagtgcat
     9541 cgattcctcg gcctaatcct ttacttttct tcacgactta ccacttcctt tgccaatgct
     9601 tggtagactt cagctcctcg agaacgtgga tcgtagtcga tgatcggttt tccatgacta
     9661 ggtgcttctg ataaacgaat atttcttgga atgatcgttt cgtaaacttt ttcgcggaag
     9721 tatttacgta cttcttctac gacttcattt cccagatttg ttcgtgcatc atacattgtc
     9781 agtaagactc cctcgatctc taattctgga ttaaagtgtt tttggactaa acgaaccgta
     9841 ttcagtaatt ggcttaatcc ttccaatgcg taatactcac actgaacagg tatcaaaatc
     9901 gaatcacttg ctgtaaatga attgattgtc agatggccaa gagaaggcgg gcaatcgatc
     9961 aaaatataat catactgact gcttacttct gctaaagatc cttttaatct tgattctctt
    10021 gccatcattg acgtcaattc gatctctgct cctgctaatt ggagagtcgc aggcacaata
    10081 ctcaaatttt cgtgttcagt gatcaaagtt gcctcatcaa ttggcaattc attgactaga
    10141 acatcataga tgtctcttgt cacatcaggt tttctgatcc cgacaccact ggtagcattt
    10201 ccttgtgcat ccatatccac tagcaatact tttttgccaa ggctagcaag acaagcacct
    10261 agattcaccg tcgtcgttgt tttgccgacg ccaccttttt ggttcgcaac agatattatt
    10321 tgtgccatct cttctcctcc tatttgattg gctgcttatt aggcagtccg ggctttcttg
    10381 ggtatttctt tggggttggt ttcttttttt gaataacgat gatatgccgt tgatcagaga
    10441 cattcggcaa ggtaaccgcc tcttctttga ggaatttacc acctaataaa gcaatcgctt
    10501 gttttgcttc tgtcaattcc tcttcacttt ttgctgcttt caatgcataa aaatagcctt
    10561 cttgtttagc caagggcaaa cacaattccg ctaacacatt caaacgagca accgcacgag
    10621 cagtgacaag gtcaaatgat gcacgaaagt gaggattttg cccaaatgtt tctgcccggt
    10681 catgatataa ggaagcatcg attcctaata atcgggttaa ctcagataag aaggttattc
    10741 gtttattcag agaatcaacg atcgttatct gcagttctgg aaaggcaatt tttaaaggta
    10801 tgctaggaaa ccctgccccc gaaccaacat cgcataaaga taaaggttgc gtaaagtcta
    10861 cttcaaatgc taatgtaagt gaatcgtaaa aatgcttcag atatacgtct ttttcatccg
    10921 taatagctgt aaggttcatc ttttcgttcc attcgactaa tgtccgataa taaatagcga
    10981 attgattcat ttgatgatcg gtaagctcta tccctttttc tgccaaggat tggcgaaatt
    11041 cttctggtat cataaatatt cctttcattg tgaaacagca attgtttcac agattctctc
    11101 cctactttaa cgcaaaatct ctagacatgc aatccttcca tatggattct taaaaatttg
    11161 aaaagtaaga aaagccgata gactttttct ttctagtatg actcataaaa tatacacaga
    11221 agagagaact agctttgagc aatttctgca aaaactagtt ctctcttcta tttattatta
    11281 cgtattacgc tggttcactg actttcgcaa tcttcccttg ttcgatatag accattagga
    11341 tacttaggtc tgcagggttt acgccactga ttcggctagc ttgggcaatt gtttctggtt
    11401 ggattttctg caatttttgt tttgcttctg ttgctaatcc gttgattgct gcgtagtcga
    11461 tgttttctgg aatctttttc gcttccatgc gttttaattt ttctactttt tccatggctt
    11521 ttttgatgta gccttcatat ttgatttgga tttctacttg ttcgatttct tttcgtgtca
    11581 attcttcatt ttctggaata aaccgtagaa gttctgcata agtaatctca ggacgtctta
    11641 aaaagtcgct tgctagtaca ccatctttta atggtgccgc attaatcgtt gctaaaaagt
    11701 cttggacttc ttctgttggt ttgattcgta cattcatcaa acgtttgatt tcttgttcaa
    11761 ctgcttcttt tttcttcaaa taattcttgt attgatcttc ttttactaag cctacacggt
    11821 gacccatttc tgttaatcgc aaatctgcat tatcatgacg taaaagcaga cggtattcag
    11881 cacgtgaagt cagcaaacga taaggttcgt tcgttccttt tgttaccaaa tcatcgatca
    11941 tgacaccgat gtaaccgtca cttcgtttga tcactaaagg ttcttttccc tgaactttca
    12001 aagctgcatt gataccggca atcagccctt gtccagccgc ttcttcataa ccgcttgtac
    12061 catttgtttg tccagctgta taaagatttt caacgacttt agtttctaat gtcggacgga
    12121 gctggtgtgg ctctactacg tcatattcga tagcatatcc tgtacgcatc atttctactt
    12181 tttctaatcc agcaatagaa tgaagcatgt tgacttgaac atcctctggt aaagaagtag
    12241 ataaaccttg aacatagact tcttccgtat ttaagccttc tggttccaaa aataattgat
    12301 gacgtggttt gtctgcaaaa cgcacgatct tatcttcgat ggatggacaa tagcgagcgc
    12361 ctaccccttc aacgatccct gtaaacattg gggcacgatg taagttgtct cgaataattt
    12421 ggtgagtcgt ctcacctgta taggtcagcc agcaagattc ctgatctagt ttataggcac
    12481 tatctggtgt gctgaagcta aaatgattcg gctctttgtc accaggctgc tcttctgtaa
    12541 cagaatagtc gatcgtactt gattttactc gaggcggtgt tcctgttttg aaccgttcga
    12601 tagcaaagcc aagttctttt agatgattcg ctagtccaat agaaggttga gagttattcg
    12661 gacctgatga atatttcaat tcaccgataa tgatttctcc gcgaagtgct gttccggctg
    12721 taataacaac tgctttggcc cggtagctcg ctcctgtgga cgtcactact ccatgacaaa
    12781 caccatcttc gacgatcagt tcttcgacga ttccttgtct tagcgtcaaa tttggttctt
    12841 tttcgatcgt atgtttcatt tctgttgaat aagcatgttt gtctgcttgt gctcgcaatg
    12901 ctcggacagc tgggcctttt cctgtgttca acatacgcat ttggatatag gttttatcga
    12961 tattcttacc catttctccg cctaacgcat cgatttctcg aacgacaacg cctttagctg
    13021 gtccgcctac agaaggatta catggcatga atgctaccat gtccaaattt attgtcagta
    13081 ataatgtttt tgatcccata cgtgcagcag caagtgcagc ttctgaaccg gcgtgtcctg
    13141 cgccaacaac gatcacgtca tacgcatctg cttcataatg ttccaatcgt ttgttcctcc
    13201 ttttattttc ctaaacaaaa ttgactgaat aattgagtga ttagctcatc ttgtacactg
    13261 tcgccgacaa cttctcctag atagtcccag caacgcgtca tatctatttg aacgagatcc
    13321 acaggcattc ctgaatcaat acctgcaatg acttcttcaa gtgagaggga agctttttct
    13381 aacaacgcga tatggcgggt attagaaaca taagtagcgt ctctttctcc tgtttctccg
    13441 ctgaagaata aatcagaaat agctgattcc aaacgatcta gtccgtcgtt tttagctacg
    13501 gaaattgaaa aaactggttc attttcgatc aatttcttca atttttcttg ttccagctgt
    13561 gctggcaaat ctgttttatt tagaagaatg atccgtttca atccacttgt cgcttccaat
    13621 aattgttcat cttctgctgt cagtggttcg ctttggttta gaacaagtaa gatcaagtct
    13681 gcttctgcta atgcttttcg gcttctttcg accccgatcc gttccaccac atcttctgtt
    13741 tcccgaattc cagctgtatc gattagcttg agcggtaccc cccgaacatt gacatactct
    13801 tcgattacat ctcgagtcgt tcctgcaata tccgtaacga ttgctttttc ttctcttaac
    13861 aaatggttta acaaacttga tttgccgaca tttggccggc cgatgattgc cgtacttaac
    13921 ccttcccgca gaaccttccc ttgcttggat gtagcaagta gcgcttggat tctttgttgg
    13981 atcatctgcg ctttttcaag caataacttc gtagtcaatt cttcgacatc atcatattct
    14041 ggataatcaa tatttacttc tacttgtgct aatgtctcta aaatctcttg tctcaatgag
    14101 cggatcaaag cagacagatt gccgtctaac tgattaagag ctagtcccat tgctttgtct
    14161 gtttttgccc gaatcaaatc catcacagct tctgcctgtg aaaggtcaac acgaccattc
    14221 aagaatgctc gttttgtgaa ttcgcctggc tcagctaatc ttgcaccttc tcttaacaat
    14281 agctgcaaaa tttgattgac tacaacgatc ccaccgtgac aattgatttc tactacatct
    14341 tcccgcgtaa atgtctttgg tgctctcatc acggagacca tgacttcatc gacaagctga
    14401 ttgctcttgg gatcaacgat atgtccataa tggatcgtat gacttggtac ttctgataat
    14461 cgtttgtttc cagattgata aactttatct gctagttgca cagcttgatc gccacttaaa
    14521 cgaacgatac tgattgcacc ttctccaggt ggggtagaaa ttgccgcaat cgtatcaaat
    14581 tctaaagtaa tttcagccat tttttcactt cctttttcat tttgcgcaca aaaaaagtgc
    14641 ccactccacc ctttatgcac aataaacggt gaacttcgca ctttgactgc ttgttcttga
    14701 ttaaattctg gtcatagatt atcacacttg ctataaggaa tcaagtgttt aaaacaatta
    14761 gatgaagttg agcctgttct gcttccatta ccttatattt aattgtcctt ggatgtctct
    14821 ttgcgttctt tggtttattc gaagagaaga tactgtataa acaaggcttt atctttctta
    14881 aaaaaaacgg tacactaaat ggtagcgcta tctaaactat acacttttga aaggagaaaa
    14941 tatgtgagcc cgttcagatc tgctgcattg gaagaagaaa gtgaccctcg gatcaacgat
    15001 gtcgttttat ctacagggaa tatcaaccag aaatatatcg tccgcgatat cgtttttgtt
    15061 gtggaatgct tagaagctga tttgtttgac ccatcttttc ccaaagatga ccttttctta
    15121 acaacgaaga ggaaattaaa gacgaaggta cttgaatatg gtgcgaatgc agtaatcaac
    15181 tgtcattttg agtatcagca aaaaaaacgc gacggaaagt attttctgga actttttgct
    15241 tatggaacag tgatccaatt tatccaaaca acgattggtt aaatgaaaca gacaaaaaaa
    15301 gcggatcaaa actgaagaca gtttcgatcc gcttttttct atcaaagtta gtgactactt
    15361 catcgtatac tctgataaga atgatttcta gtaaaatata cttggtttga aaaactttgt
    15421 caacgtgatt tattcaaaaa gtaatggaat caataatatt ttttagcagg ttctactact
    15481 aaataacgat aaggttcctc accttccgaa tgtgttttta catgttcatc tttgcttaat
    15541 gcagcatgga tttgtttacg ttcaaatgca ggcattggtt ctaagaaaac aggctgccct
    15601 gtccgtttta ctttttcagc cgtgcgatca gctaaacgct gaatgatctc ttggcgcttt
    15661 tcacggtaat tgcctacatt gactactaca gacagcttat ttcttgctaa acgatggatg
    15721 aagacttgtg ccagatattg caatgcattc agtgtttttc catgtttccc aatcagtatg
    15781 ccttgctttt gtgtttctaa atggaaaaca accatattat ttgattctct ttccattttg
    15841 acaagagctg gagcatcaag ctgttttgaa atttcagtaa gataaactgc caattccgtt
    15901 aaagctgctt catcacctag ctcacttact tcttctgttt tttcttcaag aatcgtttcg
    15961 ttgactacct cgatctcagc tgttggttct tcttccaaaa tttcttctac agtctgttct
    16021 actgtttcag aaactttttc gctgatactt ggctggatcg aaagccgtgc attctttcga
    16081 cccattccta ggaaaccttt ttttccttct tccagtattt cgatttcgac ttggtctttg
    16141 gccaaaccca aatcagccag acctagttgg acagcttcgt ctattgttgc agcttcataa
    16201 atcggcatta gcattacctc ccctattatt tccgtttttt cttaggattc attgctttct
    16261 taagagcacg ttctctttcg cggattctcc gtgcttcttc ttcacgctct tttcgaattt
    16321 tgaaagggtt gttgatcagc agcgtttgta caacttggaa ggcattggaa actacccagt
    16381 ataatgaaag accgctggct aaattgacac ccatcactaa aatcattaca ggcatcacga
    16441 aattcatgat cttcattgat gcattcgatt caatttgact catgctagat aaatacgtac
    16501 ttgcaaaagt aaagattgct gctaaaatcg gcaaaataaa tgttggatcc gcgttcccta
    16561 agttcaacca taagaaatgc ccttgtttca actctggtac acgtgaaata gattgccata
    16621 acgccatcaa gattggcatt tgtactaata aaggaagaca accagcatat ggattgacgc
    16681 cattttctgc atataaacgc tgctgctctt ctcttaactt actttgtgtt tccggatctc
    16741 ttgaactata ttgttgctgc agtgctttta atttcggttg taattcttgc gttttacgca
    16801 tgctctttgt ttggaaatgc atcaacggca ataggatcac gcggatgatc agtgtaaata
    16861 aaatgatccc tatccctgca ttaccaaatg acaacgcctt gatcgcctca gcaaagtaat
    16921 aaacaatata acgatcccaa attcctgtac tctgtgcgct gacttcccca gttccgcaac
    16981 cggataagac gatgaccaaa ctaacgatac cggccatcaa aagtaaacgt ttgtatttct
    17041 tcacttactc ttttcctctc tgtcgattat ttttgcaagt tttaagacgt ggactaaatt
    17101 ggagcgaacc tcatcataag tcaacccctt cacacttggt ctagcaatca caataaaatc
    17161 caactccgga tcaatttctt cttttataga ataaactgct gctcggattt ttcgtttgac
    17221 ttcattgcgg tttaccgcgt tgccgacctt ttttcctaca gataaaccaa ctcgaaaatg
    17281 aggctgtccc ggtttttcca aacggtaaac gacgaatttg cggttagcaa aagaatctcc
    17341 cgtatggaac acggcttgaa actctcgttc tttttttact cgatacgctt ttctcattag
    17401 ttttctttcc ttttctatct ctcacttacg ctcataatca taccataatt acgattgtcc
    17461 tttcatcatt tccctaaaaa agagtataaa aaaaaccact gaaaccccag tggcctaagc
    17521 tgaaagaact tttcttcctt tgcgacgacg gctagctaac acacgacgtc catttttagt
    17581 actcatacgt ttacggaatc cgtgaacttt ttgacgttta cgtttatttg gttggtatgt
    17641 tcttttcata tattccacct ccaaaatgtt cttatctatt ttataaacac agacatactt
    17701 tgatagtata acgacaaagt agtgattttg tcaatataaa atagaagatc gattgttaaa
    17761 acttatccac aagattattt ttttctatgg gagtcctatg tggaaaaagt tatgcacagg
    17821 gattatccac agataataaa tggctggttt tacacagaaa acacacgtgt aaaaaaagta
    17881 atccacaatc aggtgatttc ctgtgtattc cgtctcctaa ctattggtat atctatattt
    17941 tttatccaca gatgcaagag gaaatctatt gatttttacg agttttccac ctgtgcatta
    18001 gtggtgtgga aaactttttt ttgacaactg tgtttttctc ttttttcttt ttgtcgattg
    18061 tgtggataat tgtaattaaa aaattttttt cttcggtttc tgtggaaaac tattgaaaaa
    18121 aatgctaaat tagtactagt tattcacttt ttaatgaagg aggaggcctt atatggtatc
    18181 cctcgatgct ttatggaatg aattaaaagc aacataccaa aaggatttat cgcctgctag
    18241 ctataataca tggatcgaaa cagcgaaccc tcgaaccctt gatcaaaacc agctcgttgt
    18301 tgaggttcct agcaagattc ataaagaata ttgggaaaaa aacctggcga caaaaatcgt
    18361 tgaagtcggt tatatgttat caggaaatga gattatccct cgctttatta ctggcgaaga
    18421 agcagagcaa gaagaagtta tagaagaaaa aaatccaaaa gttgtggcac ctagtccgct
    18481 aaaaaaagcc atgctgaacc ctaaatatac ctttgatacg tttgtcattg gtaaaggaaa
    18541 ccagatggct catgcagcag cgctcgttgt agcagaagat ccaggttcta tttataaccc
    18601 gctcttcttt tatggaggcg tgggacttgg taagactcac ttgatgcatg caattggtca
    18661 tcaaatgctg caaagtcagc ctaatgccaa agtaaaatat gtaagcagtg aaacttttgc
    18721 taatgatttc atcaattcga tccaaaacaa aacagcagaa gagttccgtc aagaatatcg
    18781 aaatgttgat ttactgctag tggatgacat tcaatttttt gcagaaaaag aagctacgca
    18841 agaagagttt ttccatactt tcaatgcctt gtacaatgaa gggaaacaaa tcgtactaac
    18901 cagtgatcgg ttgccaaacg agattccgaa actgcaagaa cgcctcgttt ctcgctttgc
    18961 atgggggctg tctgttgata ttacaccgcc ggatcttgaa acaagaacag cgattttacg
    19021 taaaaaagcg gcggctgaac gtctagagat cccagatgac acactaagct acatcgcagg
    19081 acaaattgat tctaacattc gtgaattaga aggtgcgctt gttcgagtgc aagcttttgc
    19141 tgcgatgaat agtgaagata tttcgactag tctagctgca gacgcactga aaacgttaaa
    19201 atcaggaaaa ggacatcctc aattgtcaat cctgcagatc caagaagaag tggcaaagta
    19261 ttatcacatc caattgaaag atatcaaagg aaagaaacgc gtcaaatcta ttgttgttcc
    19321 tagacaaatc gctatgtatt tggcacgtga gctcacagat aattctttac cgaaaatcgg
    19381 agctgaattc ggtggcaagg atcatacaac ggttatccat gctcatgaaa aaatccagca
    19441 gctgatggat tctagtgtca gtatgcaaaa tgaagtatca gaaatcaaaa actttttact
    19501 aaattaattt gtcgattcta tcaactgaaa atagcatgtg gataaaagaa aaaaacgttc
    19561 aaaagttatg cacacttttt ccacagctgt tttttcgttt ctctcttacg ttttttgagt
    19621 tttccacaga atcaacatgc cctattactt ttattattct ttttaactaa taataaataa
    19681 acaaacattc aaaggagata catcatgaaa gttactttaa accgagctag ctttatgcag
    19741 gaattgcaaa ctgttcaacg agctatttca agcaaaacca cgatccctat tttgacaggt
    19801 gtaaaaatca cactgacaca agaaggtttg actttgacgg ggagcaacgc tgatatatca
    19861 attgaaactt ttttgtctgt tgaaaacgaa aaagcaaata tgcaaatcga atctactggt
    19921 tccattgttt tacaagcacg tttctttagc gaaatcattc ggagacttcc tgaagaaaca
    19981 tttactttag aagttttaga aaataaacaa gtagcgatta cttctggaaa agcgaatttt
    20041 atcgtaaatg gattagatgc agataactat cctcatcttc ctgttgtcga aagccataac
    20101 cagatgaaat tacctgtaca cgtattgact aaactaatca acgaaacagt ttttgctgtc
    20161 tcacaacatg agagtcgtcc aatcttgaca ggtgtgcatt tcattttatc tgataattct
    20221 ttattggctg tagctactga ttctcaccgt ctaagtcaac gcgtgattcc agtagaacaa
    20281 gcggctgatc attttgatat tgttattcct ggaaaaagtt tgatcgaatt atctcgctca
    20341 ttaacaaatg aagaagaaat cgtcgaaatc agcattatgg aaaaccaagt gttgttcaaa
    20401 acagaaacga tgtatttcta ttcccgtttg ctagaaggaa actatcctga taccaatcgt
    20461 ttgattcctt caagttttaa tacagaggtt gaattttctg ttcctagctt tttagcggcg
    20521 atcgaacggg cttctttact ttctcatgaa ggccgtaaca acatcgttcg tttatctatt
    20581 cgtccagatg cggttgtttt atacggaaat tcgccagaaa tcgggaaagt agaagaaagc
    20641 ttgagttata cagcaagcag tggcgatcca ttagatattt ctttcaatcc ggattatatg
    20701 aaagcagcgt tgcgtgcatt tggagatatg agcatcaaag tgaaatttat ctctgctatt
    20761 cgtccattta cattggaacc aacggaagat ggcgttcaat ttattcagct gattactcct
    20821 gtacgtacaa attaacaatg attttcattg ttcttgaaaa tttaattgaa aagaaataga
    20881 aaaaataaaa ttttaaacag aaggccctaa aatctctttt aaggctttct gtttattttt
    20941 gtttaa
//
LOCUS       DACGEU010000048        20747 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.048, whole genome shotgun sequence.
ACCESSION   DACGEU010000048 DACGEU010000000
VERSION     DACGEU010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20747)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20747)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20747
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.048"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            168..362
                     /locus_tag="IXR40_001654"
     CDS             168..362
                     /locus_tag="IXR40_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361508.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
     gene            631..930
                     /locus_tag="IXR40_001655"
     CDS             631..930
                     /locus_tag="IXR40_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361509.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(1027..1461)
                     /locus_tag="IXR40_001656"
     CDS             complement(1027..1461)
                     /locus_tag="IXR40_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4361510.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1693..2403)
                     /locus_tag="IXR40_001657"
     CDS             complement(1693..2403)
                     /locus_tag="IXR40_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HAQ4361511.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(2393..3253)
                     /locus_tag="IXR40_001658"
     CDS             complement(2393..3253)
                     /locus_tag="IXR40_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HAQ4361512.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(3258..3896)
                     /locus_tag="IXR40_001659"
     CDS             complement(3258..3896)
                     /locus_tag="IXR40_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010740138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HAQ4361513.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3911..4210)
                     /locus_tag="IXR40_001660"
     CDS             complement(3911..4210)
                     /locus_tag="IXR40_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAQ4361514.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKGVTVIGIKNVMSVKEISEKFAETKWYQKNK"
     gene            complement(4253..5737)
                     /locus_tag="IXR40_001661"
     CDS             complement(4253..5737)
                     /locus_tag="IXR40_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HAQ4361515.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQALIFMGLILGCYWTVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPDGYFLIVEDYDTYAEKQRV"
     gene            complement(5757..6218)
                     /locus_tag="IXR40_001662"
     CDS             complement(5757..6218)
                     /locus_tag="IXR40_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAQ4361516.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGENEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(6236..7303)
                     /gene="ulaG"
                     /locus_tag="IXR40_001663"
     CDS             complement(6236..7303)
                     /gene="ulaG"
                     /locus_tag="IXR40_001663"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HAQ4361517.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADPKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            7521..8291
                     /locus_tag="IXR40_001664"
     CDS             7521..8291
                     /locus_tag="IXR40_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAQ4361518.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(8564..9391)
                     /locus_tag="IXR40_001665"
     CDS             complement(8564..9391)
                     /locus_tag="IXR40_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4361519.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
     gene            9959..11194
                     /locus_tag="IXR40_001666"
     CDS             9959..11194
                     /locus_tag="IXR40_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HAQ4361520.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            complement(12193..12453)
                     /locus_tag="IXR40_001667"
     CDS             complement(12193..12453)
                     /locus_tag="IXR40_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HAQ4361521.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(12480..13781)
                     /locus_tag="IXR40_001668"
     CDS             complement(12480..13781)
                     /locus_tag="IXR40_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4361522.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEEAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNAALLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPIIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            complement(14073..14531)
                     /locus_tag="IXR40_001669"
     CDS             complement(14073..14531)
                     /locus_tag="IXR40_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HAQ4361523.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            complement(14544..15869)
                     /locus_tag="IXR40_001670"
     CDS             complement(14544..15869)
                     /locus_tag="IXR40_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005227470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HAQ4361524.1"
                     /translation="MKKQIITIAGGGSTYTPGIVQAILNNEKRLPLSEIRLYDIDEER
                     NMDMYLIVKFMLKRKGFSNIRIRATDDPKLAFTGCDFVFSQIRVGGLEMREKDEKIPL
                     KHGLVGQETCGLGGFAYGMRSIKGLLEIVDHIQDYAPKAWILNYTNPESIVSEAVRRK
                     YPNVKMINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIYDKELQREIMP
                     EIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITKNFPSNIPNNYLEYYLYPDMVVEH
                     TDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVLNFNFGEHGQYIVDIAISLLNDDR
                     RRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVEPITLRKPISDFHKGLMEAQVAVEK
                     LLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILDEMIKVNKKYWPALK"
     gene            complement(15886..17298)
                     /locus_tag="IXR40_001671"
     CDS             complement(15886..17298)
                     /locus_tag="IXR40_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4361525.1"
                     /translation="MNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADDMLNIPVIGAA
                     GNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMDPEVNMGIFGG
                     IISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAVFLGFIWPLIQIGI
                     DNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSPSKEVFRGEMT
                     RFINGDPQAGLFLSVFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMGSGAGTSFIAN
                     ITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVDYLINFRIATN
                     AILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEETELGLASKNYE
                     YMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISGIIKPTEKNYQ
                     IIIGLEVTYVMAEFNKLLEE"
     gene            complement(17315..18079)
                     /locus_tag="IXR40_001672"
     CDS             complement(17315..18079)
                     /locus_tag="IXR40_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HAQ4361526.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            complement(18183..19058)
                     /locus_tag="IXR40_001673"
     CDS             complement(18183..19058)
                     /locus_tag="IXR40_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAQ4361527.1"
                     /translation="MKESASCFVLSYRGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAVEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            complement(19313..19397)
                     /locus_tag="IXR40_001674"
     tRNA            complement(19313..19397)
                     /locus_tag="IXR40_001674"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19361..19363),aa:Leu,seq:caa)
     gene            complement(19415..19486)
                     /locus_tag="IXR40_001675"
     tRNA            complement(19415..19486)
                     /locus_tag="IXR40_001675"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19452..19454),aa:Gln,seq:ttg)
     gene            complement(19496..19568)
                     /locus_tag="IXR40_001676"
     tRNA            complement(19496..19568)
                     /locus_tag="IXR40_001676"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19533..19535),aa:His,seq:gtg)
     gene            complement(19630..19714)
                     /locus_tag="IXR40_001677"
     tRNA            complement(19630..19714)
                     /locus_tag="IXR40_001677"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19678..19680),aa:Leu,seq:caa)
     gene            complement(19735..19805)
                     /locus_tag="IXR40_001678"
     tRNA            complement(19735..19805)
                     /locus_tag="IXR40_001678"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19771..19773),aa:Cys,seq:gca)
     gene            complement(19851..19922)
                     /locus_tag="IXR40_001679"
     tRNA            complement(19851..19922)
                     /locus_tag="IXR40_001679"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19888..19890),aa:Gln,seq:ttg)
     gene            complement(19934..20006)
                     /locus_tag="IXR40_001680"
     tRNA            complement(19934..20006)
                     /locus_tag="IXR40_001680"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19971..19973),aa:His,seq:gtg)
     gene            complement(20009..20082)
                     /locus_tag="IXR40_001681"
     tRNA            complement(20009..20082)
                     /locus_tag="IXR40_001681"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20048..20050),aa:Trp,seq:cca)
     gene            complement(20089..20169)
                     /locus_tag="IXR40_001682"
     tRNA            complement(20089..20169)
                     /locus_tag="IXR40_001682"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20133..20135),aa:Tyr,seq:gta)
     gene            complement(20171..20246)
                     /locus_tag="IXR40_001683"
     tRNA            complement(20171..20246)
                     /locus_tag="IXR40_001683"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20211..20213),aa:Phe,seq:gaa)
     gene            complement(20282..20354)
                     /locus_tag="IXR40_001684"
     tRNA            complement(20282..20354)
                     /locus_tag="IXR40_001684"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20319..20321),aa:Asp,seq:gtc)
     gene            complement(20364..20436)
                     /locus_tag="IXR40_001685"
     tRNA            complement(20364..20436)
                     /locus_tag="IXR40_001685"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20401..20403),aa:Val,seq:tac)
     gene            complement(20452..20523)
                     /locus_tag="IXR40_001686"
     tRNA            complement(20452..20523)
                     /locus_tag="IXR40_001686"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20488..20490),aa:Glu,seq:ttc)
     gene            complement(20538..20627)
                     /locus_tag="IXR40_001687"
     tRNA            complement(20538..20627)
                     /locus_tag="IXR40_001687"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20591..20593),aa:Ser,seq:gga)
     gene            complement(20667..20740)
                     /locus_tag="IXR40_001688"
     tRNA            complement(20667..20740)
                     /locus_tag="IXR40_001688"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20704..20706),aa:Asn,seq:gtt)
BASE COUNT         6558 a         4342 c         3291 g         6556 t
ORIGIN      
        1 taagaacaat agccttttat tatatatatt attcaaatta gttatatcga gtgaaaaaaa
       61 ctttcaaatt gattcttttt atttatcata aagatataga tacataatca ttttcactta
      121 catatatttg aatattaact aaaaacagca agaaagaaga ggatcaaatg tattatgtag
      181 aagtaaaaac aaaaggcgtc aaaaacaaac aatatgtgaa aggtatcagt aacgaatatc
      241 ctttacttgg ttcatggaaa gaagctgctc ctttttccaa accatgtgcc ataaaaataa
      301 agaacgagct agaaaaagaa ctgacttgtg gtaaagctgt tgtagatatc atcgaaaagt
      361 aaatccaatg tatagaaagg aagatcacac atgaaaagcg acgtacaaat tgctaagatt
      421 atagaattag aagaagaaga cgcagtgttg acaattgaaa aaaaataaat gtttgtatac
      481 catatgatta tttcaatatg tatcctggaa ttggagatct cgtagagcta tatcaagatg
      541 aatcaaatat acttgtcatt catcatgaaa tatagagact tataaaattg tttattttta
      601 taatgtatca gtatagaaag gaaataaaac atggattata ctgttgaatt tgacagtgaa
      661 ctacttaagc aatttccaca agaagaacat ttcatgtata aagaagcaat ttcccacaaa
      721 gtgacagagt atttggagca taattttttt cgtataaagc cagtgcgtac tcgttcggca
      781 aaaggaatat acgagatgaa agtcaaaatt aataaaaaaa attatcgcat agcatttgct
      841 ttaaaaaaaa atcatgtgtt cattttttat attagttcga atttgcaaaa aattgtattt
      901 gataaagagg tgagtaaaaa aataaaatag ctgagcattg gaggatagat tgagtgatac
      961 taagtctatc ctcttgtttt tctaaagaac taagctagaa ttttttcttt tgtacgttat
     1021 tatatgttat ttgtcattac caaaaagcac cttttttctt ctagtatcta tgacataaga
     1081 aataccaccc atttccttta cttgaacaaa tcctactgat tcataaaatt tttttgtttt
     1141 ctcagtatca tctgtcaata attcgatttg gactggtcca taactagtga tcttctccaa
     1201 agcttcattc aaaagcactt tgcctattcc ttggcgctga tacctcggat gaatgaggat
     1261 atcttgaata aatgcgatcg tcgcaaaatc agtgatccaa cgaacgattc cgataatctt
     1321 cccttcccca ttacgcttta tcagagattc agattgttca aatgctctag ctaaccttgc
     1381 agtgtctttt gtgtaattcg tccaaccaac gctcttatat aattcagaaa tctcatcgat
     1441 cataagggaa tcaatattca tttttttctt cctttcttat acaattctcc ctctaataat
     1501 acagttcttt gactatttaa tctatcacat ataactctcc tgtaaagatt ctctcgattc
     1561 cttaaaattc ctctttcctt ttagaatgca tactttttga taaataaaaa ggttgtgata
     1621 aattttcttc acaacctctg tttctctcta tcaagtgtta tcttttaatt ttctaccctt
     1681 accctagcat ctctattgcc cgtagtatgc atactttcca tgtttgcgaa aataatgttt
     1741 atctagtaaa tattgcggga tttcacatat attggggttg atcagctcgt tttctttggc
     1801 catcagacaa atttcatcta agatcaaact gttttctact gctttcatag gtgaatcccc
     1861 ccatgtgaac ggtccatgtc catagacaag tactccaggg acttcgtttg gatctaattt
     1921 tctttcctta aacgtctcga caatcacatt ccctgtatga acttcgtaag cttctcttac
     1981 ttcttctttc gttaattggc gtgtacaagg aaccttacca taaaaagcat cagcatgagt
     2041 cgtgccataa gctggcaaat cgcgtcctgc ttgcgcccac atgacggagt gcgtggaatg
     2101 agtatgagta atagcagtta tatcttcaaa agtttgatac aaaacaacat gtgtggggag
     2161 atctgaagat ggttttaagc tatcttcttc tattatattt cccgacaaat ctgttaccac
     2221 catttgatct gcttgcatgc attcatatct gacaccgctt ggcttaatga cgatgactcc
     2281 tagctcacgg tccacttcac tcacattgcc ccaagtcaat ttgactaatc cgtatcgcgg
     2341 caatgccaga tttgcttcaa ggacacgttg cttcattgct gcaatttttt cttcacaaga
     2401 catcatagcc agcctccttc aatttagaac ttaagtagtc ttttgcctgc tggatttctc
     2461 ttcgaaagtc ttggcttttt tcactccaca tttcaatcag aaatgttcca tcataatcta
     2521 gacgtttcaa atgtcttaat aatccaagaa aatcaacaca accgctacca aaaggaacat
     2581 cacgaaactg gcctgaatat tcttttgtta cagggtaagt atcttttaag tggatagcag
     2641 tgatataatc gatccctttc tcaagttctc gagccggatt attttccggc catgcggaca
     2701 aattgcctag gtctggatat acttgtagaa aaggtgaatg aatctgttct ttgatttcta
     2761 aaaattttga aatggagttc ataaatggat catccatgat ttccacggaa agaatgatgc
     2821 catatttaga agcttccttt acgctttctt ttattccttc gataaagtct tctctggaat
     2881 tcattgattt ctcttcataa taaacatcgt atccagctat ttggattact ttgacgctta
     2941 gattatgcgc caaatggatt gcttttttca ttagttgttt cgctgctttt ttcttttctg
     3001 gatcagcaga accaaacgga aatcgccgat gcgcacttaa acaaatcgaa tggatacgta
     3061 caccggagct gaacatctct tctctcagct cagctatctt ttcttcagac caatctaatc
     3121 gtgctaaccg ctcatccgtc tcatcaatcg acatctcgat aaaatcgaag tccatttctt
     3181 ttacaaggga aaaacgttct ttccatgaaa tatctttggg taacgctttt tcataaatcc
     3241 caatttgagc catttcctta cccccagata cgaatgatct catctttgaa gttttgtgcg
     3301 gccttcatcg gatcatttgc tgctgtaata ccacgaccag tgataaaggt atacacatcg
     3361 atcccttcaa ataagtgtaa tgtgtgtgga tttaatccac cagttacaga aacattaaag
     3421 cctagttcaa tcagtttttt gatcttcgat aaatcttttt caccccaagt ttcaccagat
     3481 aacagcgcat cacggctttg atggtagatt acctgccgga taccgatgtt atgccaatcc
     3541 atggcttgtt caaaagtcca attgccgtag agttctactt gcaattcacc tatttctttt
     3601 tgtgctgcct ccatagttgg aatcgttgca caacaaatga ctgtcatcca gtctgctcct
     3661 gcttttgcaa cattactcgc cactgttcct ccagcgtctg cacatttcgt atcagcgact
     3721 agttttttat ctgggaacat actgcgaata cagcgaatcg ctttttgtcc ttcctgtaag
     3781 caaagaattg tgcccacttc aataatatct actacatcac caactttcat aacatctcct
     3841 aatgcatgtt ctaagtcatt gtgatctaac gcaatttgca aattcggcct gctcatctta
     3901 gttccttcct ttacttgttt ttttggtacc actttgtttc agcaaatttt tcactgattt
     3961 ctttgactga catcacattt ttgataccga taactgtaac tccttttttc tctgcctgag
     4021 taaacatatt caaaaaattg actggcgtaa aaactacatc gtattggcca gctgaacttt
     4081 ttccctctga aatggcacaa tgatggattt tggtaattgg tacgtttagt tctttcattg
     4141 ctttttccac acttctcatc atcatcaagc ttgttcctga tccatttgca cacgatacta
     4201 aaattctcat cttaatccct ccattatgag tgttgtctaa tcagattttc ttttatactc
     4261 tctgcttttc tgcatatgtg tcatagtctt ctacaatcaa aaaataacca tcaggatttt
     4321 tccgatattg taactgcgga atagccaata aaccaatgac aactacggca attccagcat
     4381 aacctaggac tttcatgatt actgtaaaca atggccaagc tgttgcccag tcgaacatcc
     4441 cgatataacc accgtatgtt gacatcccaa tccatgtagc gaataatgct gaaccgccta
     4501 cttgtatgat tcctgaaaga aacgggaaca ggcaagcggc tttgaatcca cctcggttat
     4561 tggcataaac tgctataacg gcattatcaa agaacaacgg aatgaaaccg gctatgacga
     4621 tcgttggtga tttcaataaa atcagtaaac caatcatcaa aaactgtccc aaagcaccaa
     4681 acaagaaccc aatcgttacc gcatttggcg aaccaaagcc aaaagtagca gctacgtcaa
     4741 ttcctggaac agctcctggt aaaatcgtgt ttgagattcc ttggaaagat tgagttagtt
     4801 catcgacgaa tgtccgaaca cctaattgca agatcgccag atataccgca aaatttaaag
     4861 aagtcgtcat aatgtagaat aagaaactct gcccttcttg catgaattgc gcttgaatca
     4921 aataatcttt gcctagtaca atcagaatga tcccaaagaa aaatagcatg agtaacgaag
     4981 tagcaaccat attctcattg aaaatcgaca agaatcctgg taatttgata tcttcaattt
     5041 ttttgtcttg cttgattgat ctatttttct tttcatcccg ctttttcatc cactcagcta
     5101 attttgcaaa tataaagatt ccgaacattt gctgatgtgc cactgcaaat ccggcacctt
     5161 ctgtcaattc ctgcgtgatt cctactgtta agttagaagc tactgtccaa taacaaccta
     5221 aaatcagtcc cataaaaatc aatgcttgta tcctacctag atcaggaaag caaaacagta
     5281 aaatccaaaa agcggtagct gcttgttgaa cctgaacgtt tccggtagtg aaaacggaac
     5341 gcagtttcgt atatttctga aaacggacta ataagatatt taaaacaaat gcaatcagta
     5401 ataaaatcat cacatctcca aaggtacggc caaatgtctc cattaatcca gcatccacag
     5461 cattttgtcc aaaataagga tctgtaacca tggcatccaa attgaaccgt tcctttagtc
     5521 caaccaagat tggccgaaaa ttattgacca aaccaccaga gccaacagtc aaaataaagt
     5581 aaccgaccgt tgcctttaag aatccagcga tgcattcatg aagcgggcgt ttcagcaaaa
     5641 tatagcctaa taacacgata aaaccaatca ggtatgctgg ctgcgtcaag atatttgttg
     5701 caaaatacgt ccaaatgctt aacaaaaatt cccccatctt ttttctcctc tatcaattaa
     5761 ttatattctg ccatcacaac ttggtaatca tcgatggagt tcgtagagat gagacgctca
     5821 accaatccat ctgtcattaa taattcggat aatttttgga tattttctag atgttcttct
     5881 ggatcttttg ctgcgagtgt aaaaaacaaa ctagccgttt tctcctcatt ctccccttca
     5941 ctttcaaaac ggattggctg tttcaacttg gtaaatgaaa tagctgttcc aaaaacacca
     6001 tcactttttt ctgaagaatg cggcattgct acttgaggtg cgatcacaat ataaggaccg
     6061 tatttttcta cacaatggat gatctcctcc acatacgttt catcaataat ttccttatcg
     6121 atcaatacaa gacagctttc ggcgatagct tcacgccaat ccgtgatttc tttatctggg
     6181 taatgaatca attgatggtc aaaaaagtat ttcagcaaga aactcccctt ctttcttata
     6241 aaaacgacgg aaacggtgta tcattttcaa tcgagaagac atcttcaaat cctcgataaa
     6301 aattaaactc aagatcatct ttgtttgtcg gatagatgaa tttcccgcct acttgccaga
     6361 tataaggttt aaatccatac ttcaggcgat cctttttgaa tttccaaatt tcagtgatct
     6421 cttttggatc agccataaaa ttagaccaaa tatcgtagtg gacaggaatc actacttttg
     6481 cattcaatga ctccgccatg cgcagcatat caacagaagt aactttgtct gttatccctc
     6541 gtgggttttc accataggcc cctaaacaga catcgatttt gtgttcatta ccatgtttgg
     6601 caaataaatt ggagtaatgt gaatctcctg catgataaag attccctcct gatgtttcga
     6661 ataaatagtt tactgcaatt tgatccatct cctgaggcat ttttcctttt aatacctctt
     6721 ctggatcttc acaagtgacc aacgctgtcc gatcaaacgc ttctaaagct actacattga
     6781 tgtctttgat tttgactgca tcacctggct ttactgtaat cgttttttct tcaggaattc
     6841 cccatttttg ccacgtgcga accacttctt ttggcccaat gaatgttgct tcaggacaat
     6901 tttgatgaac tgctgcggct gtatggatat ctagatgatc ggaatggata tgtgtaacga
     6961 ttaaagcgtc tacatttttt atcgcaaaag gatcgattac gaaaggctga gtacgtaaat
     7021 taggctgcat attttgaacg ccactcatac gcatcatctg atggcctttt ttcatcatgc
     7081 cattcccatg actacgtttt cccgtcccac accatagatc acataaaata ttcgttcctt
     7141 catgactttt cagccaaatt cccgtacagc ccagccacca catagcaaaa gttccaggat
     7201 ccactacttc tgtttcgatt tcttcattca agtatgtgcc ccactcagga aatgtttcta
     7261 ctaaccactt ttcttttgtt acttcattga cagttttact catttgcttg ctccccccat
     7321 atcgttgttc caacttacaa gtaaatatta atgtgtatca gcatccatga aaaccctttt
     7381 atatgaccgt ttgtttttta tatgattttc tttcagtaat caatgattgt ttcagtataa
     7441 taaagacaga tatgaatgtt taaatgaaca actagtcaaa taaatccatg gatcaagatg
     7501 tccctcagga ggcaaaagtc atgaaaaact cacttgtcaa tattgaaaaa cgtcaaaaag
     7561 aaattttgga actgcttcag cagactgaac aactatcaac tttcgaatta gctgaatccc
     7621 ttgatgtatc tattagtacg atacgaagag atttaaattt attagaagaa aaaaacgaga
     7681 tcatacgcaa ttacggttat tgttcttata attacaaaaa ccagactgat tttgatcaat
     7741 ctggtcctga aaggattaaa caagcgattg ccagagaagc tagtaaatac attaacgatt
     7801 atgatacgct gtttatcaat tctagctcga ctgcgttgaa aacactggat tttcttcaat
     7861 ctaaccattt gacagtcatt acaaacaacg tgaaaatcaa ttactctccg cacaaagata
     7921 attgtagtta tattttaact ggtggagaga tgcgctttcc aaaagaagca ctagtgggcg
     7981 acatcgcatt aaatacgatt tcttcagtca atgcagacat ttgtatcatt ggctgtagcg
     8041 gagtcgatgt agtacatggg gtcacaacaa agatattaaa tgaatcaacg atcaacgaaa
     8101 tgatggtcaa caagacaatc aaatgtaaga ttttagtcgc tgatcatcga aaaatcggac
     8161 tgacatcaaa gttcaagatt gctgatattt cagtctttga ttatttgatc actgataaat
     8221 tttgttctga aaaagtatta gaggagatca gaaatacggg gataaaaacc attcaagtag
     8281 attcatttta agaaccagga cgtaaatatg taaataggat tatcaaaaaa atgaataaca
     8341 aatttatcga taaatgaaaa acacgctacg ctcaaattga taaaggaatc ccaagatgta
     8401 tccatccaat cgataccatc ataatctatt gcttctttta taaccgttat atgttgccta
     8461 aataggaatc aaacaatatc gaaaaaagga ggtatgacaa aagtcacacc tccttttttc
     8521 gaataaacgg tattcaaatc agaacactga tttcacaacc actttatttc aggtcgtttt
     8581 caatcacctt taccgcgtaa tcatttccgt tgaaacgcgc tatttttttt gcgtccatat
     8641 atctttctaa ataatcatct tctcctaatt gcttatggca agaagcaatt tcataaagca
     8701 agtattccaa tgcataagtc gatttatgtt tcttattata ctcaataccc ttctcacata
     8761 attggattgc tttatcataa tcctcgattt tacggtaata ggtggcgata tcataatata
     8821 caatgcagac catcagatta tcaaaatcag tctcactcaa tattttaagt gtacgctcca
     8881 cataaacttt cgcaaaatct aattctcctt ttgacaagta gatcattgcc acgtttgcag
     8941 ctgcttgtaa gtgatggata tctgtttcgg tcgtttgttc caacacttga ttaaaataaa
     9001 ataatgctgc atctggtttt ttcgcataaa gatgatcaag cagtccttga taaaataaaa
     9061 tttgatttaa aagatcagaa ttacttactt tttcctgatc gatcgtttgt aaaattttat
     9121 aagattcttg gtattttgat acagaattca atgattgaat ctcatttatt tttttcctga
     9181 ttttgtcttc ttctgtttct actaatatat cggagatctc gacattcagc tttttgcaaa
     9241 gcgcacttaa gatattgatg cctggcgaca tattcttgtt ttcgatattg ctgacagttg
     9301 cttgttcaca aatgccttct gctaattgta cttgtgttaa cccctttttc tttcggtatt
     9361 cttttagtaa tgctccatct actttaatca aaacaatttc cttcccttta aaaaattatt
     9421 tctcctttat atcatacaca aaaaaaagtt ctaaacaacc aaaaatgttt agaacagaat
     9481 aaaaatttta attttaaaat aatattcaaa ttaaacaact ggcgtatctg ctccttgatt
     9541 tctttttgtg ttatctgaat aattatcgtt tacagttata acacatagtg aaaattgtca
     9601 tggcgagaaa gtctaagaat atttttaaac ataactattt ctttcttacg tgtgtataat
     9661 gacgacagca cacctatcaa ttaatataat tattttattt ttttatgttc tcatgtttat
     9721 ttttaatgac acaacttctc gtatttatct ggcacaacat ataaatcgat caaaaaattg
     9781 ttgcgtgttt ttttgaaaat tggagtttca acttgattac aaaatttaaa tttagaagtt
     9841 gtgaaaacag cgagagacag tttaatattc aaaatataca taggctactc gaacgctgtg
     9901 ttttttagta tactagtaag aaacgaaggg atagactcat tccaataagg aggatttcat
     9961 gaagacaatt ctttttgctc ctgcagtatt caatttagct gagacaacac gaatgattga
    10021 ggttgccaaa gctatgaaag accgttatta ctgtgtattc tttggctttt ctaaaacttt
    10081 tgctcctttg atcacagaaa gtggctttga gtatcattta ctagcgccga tccttacgaa
    10141 aaaacaagaa gaacaaatca taaaatttga ccagttgcgt acacttaaaa acccttttac
    10201 caaagaaatg gttgcctctc gtatcactag tgaacagagt ctgattgcta agtttgagcc
    10261 tcgactgatt gtgacaggtt cgaatgtgac aattttttta tcggcccgca ataaaaagat
    10321 tcctttagta tatgttaaac cctatgcttt gagtgaacct ttttttcaat cagagcatgc
    10381 gctgatgccc cacgagttac gtttcttcgg ccctttaagc aatccccttt ggcactggac
    10441 aaaaaagcgt atagtaaata cccgatggat ccccaatgcc ttcaaacacg ctgcacaaaa
    10501 agaaatgctt cctttaccaa aaacaagttt acaaatgatg gatgctgatc taaatctcat
    10561 cacaacgcct aaactatttt tggaagaaga acagctgccg gaaaattatc gaatcgttgg
    10621 tccaattttt gctaagctca gtacttcctt gcctgaagaa gtgctaactt ttatacagcg
    10681 aaagcaacaa gaaagaaaac gtattatcta tttcgcaatg ggtagttcag gcaatccgcg
    10741 tatgttacgc aaaattttgt tcttcttaca aaaacaaccg gatctagcgg ttattgcacc
    10801 tattgactat ctgcttgatg acattcaatc tgactcagaa gatcttttaa taacagaata
    10861 tctgtctagt catcttttgc atgaattcat tgatttttct tttatccacg gcggggaagg
    10921 gaccgtccaa actgcctgtg aatccggcaa accgtttatc ggtgtgggga tgcaatttga
    10981 gcaaagctgt aatattgact attgtgtaaa atacggaaac gcaatcgccc tcacaaaacc
    11041 agtgactgaa agaaaactgc agattgctct gcgcgaagtt tcttcaccca agattcgtca
    11101 gcaggcacgc acgctgcaag ccgtttttcc aataaatggt ccacaacaag caattcaaga
    11161 aatcgaaacc ttcctgagca accacccaat atagtttcaa gtagaaaaag cttttttaat
    11221 agagactcat cagtaatttc gctattcgag acccagacag tgaaaataca aaaaaagtaa
    11281 atagtggatt gaaaagttag agttacttaa attacggtgt ctaaaaaaca caaaatcatc
    11341 cttaaaataa aagatctgac gctatccaaa tgagcatagg tagcgtctgc catttattct
    11401 tagtcaaatt ctttgacacc tttctctggt tggatcatct caacgtttct tcaaaagaaa
    11461 gaccataata attaggcaaa tacattttct taaaatgtgt catatagatc tagaagcatc
    11521 gctttgtaga gatttgtgcc gctagtcccc tcaacaatta ctaaatcaaa tgtaggattt
    11581 accactttat ctttgataat caacctccct cttctgttga gacaatgatc tcgcaatccg
    11641 atgcatactc ctatataaac tgccagcaat ccccacatat tgagtagatc atgtcagaat
    11701 gttctatgtc gtcagcaacg atacactaaa agtcacgttc accatgactg attgctattc
    11761 ccagcacaat tatttctata cacgtttcat gatttgaata aacactcaca tcatacatat
    11821 taccattcat acaccatact gcagccccta ctatatggtt gtaagctccc aaatctatat
    11881 ttgacttgat cactttggta gtagatctac taattctaaa tccattgctg ataaaatttc
    11941 cattttttcc tccttctttc tgccaaaaca gttaaaacaa taataatctt tatgtaaaaa
    12001 agggctgtga caaaagcctt gtcacagtcc catattccga ataaacggtg gtcaaaagct
    12061 tgcatctgcg gtaataagtt caaccaaacg aaaaataagc caacatttca caaaaattta
    12121 agaagcaatt ttcgtaaatt tcttcttatt tcttgaagct aaccacttct gttacaacca
    12181 cttttagaac atttaaagct tcgatgtgac aaaccatcta tgctgctcga tcataaaatt
    12241 gatagcaaaa attccacaaa gtacatatgt cccccatgaa aacaaaacat tcatatgcgg
    12301 tacaatgatc tttggaagaa tcacgatcaa aaatgatgcc agtgcccaaa tccatcgatt
    12361 gatttgaata tgatatgtag ctagcatatt caatataagg tgactagccg ttaataaaaa
    12421 gataaaaaca aaaaataaaa tcagccaata cattgtttcc caccttctaa aaaccaaact
    12481 tagacagtct ggacttcgtt ttctccacga ctttgttcat ctgacagcat ctttttatca
    12541 taagctttta caaatggata atagataata aatgctatca atgtgttgat catgatcaag
    12601 ataacaacac gccagtcatt tcctgctgaa agataaccgc cgattggagc tggtaatgtc
    12661 catgttggca aaacagtaaa tctattgacc atttctaatt tgactgcaaa ataactgata
    12721 atagtcaaaa ctaaaggaac taagttgaac gggatgaaca tgtaaggatt caacatcata
    12781 ggagctccaa aaattatggg ctcattgata ttgaagatac caggaataat agaaaaacga
    12841 ccaacctctt tcaagaattt tgatttacag aagaatataa acaaaacaga taccacgatc
    12901 gttgctcctg caccaccaat tgttaccgtc cattgataaa actgttcagg agcgatatag
    12961 ggtaattggg tggcagctgt accatctgcc aatgcctttg cattctcatc caacatgatc
    13021 agccacattg gacgaacaac agcccctaca atactcatgc catggatacc aaatgaccac
    13081 aacaaatgga tcaaaaacat tggtagtaaa acaccaagca aattattccc taaaatattg
    13141 gttaaaggct cgaataacga taataaggca gcgtttacat caaagcccgc gacgcttcga
    13201 atcagccaag taattgttaa aatgactgca cctggaatca atgcctcaaa actacgggca
    13261 acagcaggtg gcacttgttc tggcattttg atagtaatat ttcgattttt aaagaaacga
    13321 tatacttcca ctgcaaaaat catagataag atccccgcaa acatcccaga tgctcccaaa
    13381 gaactcatag gtaagaccca gccaagaggt gcctcttcag gagttaaaac gtttacagga
    13441 acttgtaaca taaagaacgt tcctaaagat aatataccac ctgtcacact atctaatcca
    13501 tatgatttag ctagatccga acccataaca aaagttgcat aaatagccat caatcccatc
    13561 gtcatcctaa agggtaaaac aatcgttgcc gaataagggg caataaattc attccatcca
    13621 ggaaacggta aattgataaa gaccataaaa aatgtcccaa tcaaaatcaa tgacaatgtt
    13681 gaaacaaccc cattacgaat tgctaataaa tgacgctgtg taccaatttt tgccattggt
    13741 gggacaagtt tctcttcgac ccatttcatc agcttttcca ctaaaaccac tccttttcaa
    13801 taaaatatga accattcatt gcatgacaac gcaaagaatg ttcataacta attatataat
    13861 taagaaattt tatttcaata tattctctta aataatcaaa tttattttta agaatcctga
    13921 aaataagttt tctaaatcat aggagcaaca aaaaaattcg ataattaaca aaaatcaaaa
    13981 tgattaaatc tagtgattga aacatatcat ttcaaaaaaa ttttgtaaat tcacccataa
    14041 atatcaccct atttaacttt tttcatcgta cactaaaatt caaaacaact atctttaatc
    14101 tttacttctt ggttttgttt taataaattt ccttcaaaaa tgcctggaga aactacaatg
    14161 atcaccgtat ctttttgtgc ttgctccaac ttcttcaaat ctataatagc taacagtgtc
    14221 ccttctttta cctcctggtt actttcaacc cgtatctgaa acggacttcc ttcgagttca
    14281 actgtatcta aacccatatg gatcagtatt tttctgccag attcactttc gatcgttatg
    14341 gcatgtcggg taggaaatat attatcgatt attcctttaa ctggcgcatg gatatatcca
    14401 tcatgattcg ttatagcgta tccaactcct atcatttttg aagaaaagac ctcgtctttt
    14461 actgctgtta atggaataat ttgaccacta gctacagctt ttagaatgtt tcttgtttta
    14521 aagaaatgca ctttttatca cctctacttt aatgctggcc aatatttttt gtttactttg
    14581 atcatttcat ctagtatttt ttttgcgact ctggcatttg gtacggtttg attcaatgta
    14641 aatgcttgta aagctttttg ataagaacct tcaaagtaag catctactag taacttctct
    14701 actgcaactt gtgcctccat caatccttta tgaaaatcac tgattggttt tcttagtgta
    14761 attggctcca caccagttgc accaacatat gccggtattt caacaactgc atctgaccgt
    14821 agattcggaa tcgccccttg attaggaacg attagcataa agcgacgacg atcatcattc
    14881 aacaaggaaa tagctatatc gacgatatat tgtccatgct ccccaaaatt aaagttcaat
    14941 acttcttcca caataccgcg gcgtatttta tcagccattt ctttggtatt tttctctcgt
    15001 ccatccatga ccatattagc acgtgtatac tctttgtcag tatgctcaac gaccatatca
    15061 ggatataagt aatactctaa gtaattattc gggatattac ttggaaaatt tttcgtgatg
    15121 actgacatca tttgaaaggt tttttgccaa gttttatctc ctatattaaa atcggcgact
    15181 tgcatttctt ttgttattag tttttcaata atctctggca taatttctcg ttgcaattct
    15241 ttatcataaa tcgatgtata ccagccaaag tggtttaaac cataatacgt aacgatccaa
    15301 ttcttacgat cataaccgta attcactgca atcgtttctt caattgaaat agtcatatca
    15361 caggcattaa tcatttttac attcggatat ttacgacgaa cagcttcaga aacgatcgac
    15421 tctggatttg tataattcaa aatccatgct ttgggggcat agtcttgtat atgatcgaca
    15481 atttccaata aacctttgat tgagcgcatc ccataagcaa atcctccgag tccacacgtt
    15541 tcttgtccta ctaatccatg tttaagtgga atcttttcgt ccttttctcg catctccaat
    15601 cctccaacac gaatttgtga gaaaacaaaa tcgcatcctg taaaagcaag ctttggatca
    15661 tccgttgcac gaatgcgaat atttgaaaaa ccttttcttt tcagcataaa tttaacaatc
    15721 aagtacatat ccatatttct ttcttcatca atatcatata aacgtatttc agataatggc
    15781 aaccgttttt cattgttcaa aatggcttga acgattcctg gtgtatacgt actcccgcct
    15841 ccagctatag tgataatctg ttttttcatc atcatctttt cctttctatt cttctaataa
    15901 tttattgaat tctgccataa cataagtcac ttctaagccg atgataattt gataattttt
    15961 ttcagttggt ttaatgatcc cgcttatccc taattgcttg attcgctgtt cctcgaccat
    16021 ggtgggatcc actacctcta cccgtaggcg tgtattacaa ctatagacat ccaggatatt
    16081 ggcttttcct ccaaacgctt gtagcatttt tgttgccata tattcataat ttttacttgc
    16141 taaccctaac tctgtttctt ctaaggttac ttcattgcca aactctgcct tagcttcacg
    16201 tcctaatgtc tgaatgtttc tcttattgat caaataataa aaagtaacgt aatacaaggc
    16261 aaaaaagaaa attccgattg gaagaatcaa aatagcattg gtagcgattc gaaaattgat
    16321 gagataatca acaatacatg ctccgaatgt aaaaccaatt cgtatattga ataagtaaca
    16381 gacaatccct gctaaaccgg caaaaagtgc atggatcacg tacaacatag gagaaagaaa
    16441 catgaaacta aattcaacag gctcagtgat atttgcaata aatgaagttc ctgcaccgct
    16501 tcccatgatt cctttgacca tctctttatt ttctttataa gctgctttat agatagctag
    16561 acatatagct ggtataccaa acatcattac tacaaaaaaa actgataaaa acagtccagc
    16621 ctgaggatct ccgttgataa agcgtgtcat ctctcctctg aaaacttcct tgctaggaga
    16681 tgtatagctt cctaaatcgt aataaatata cgtattcaac acatggtgca gtccaaaggg
    16741 gatcagcaaa cgattcaaaa acataaatat ccccacacct aatgctccca tatcaacgag
    16801 cagttttgca aaattatcaa tcccaatttg gatgagcggc cagataaagc ccaaaaaaac
    16861 agctgcgatt gtttgtagaa tcatcaccat agtcaatggg aatttttcgc ccgcaaaata
    16921 agaaaaaact actggtaatt tttgttcttt aaagcgatta tacgtccatg ccgctactaa
    16981 accggaaata attccaccaa aaatccccat attcacttct gggtccataa tttctaagcc
    17041 ttttttcaag gtagcaatcg ctaaaaaacc agtaagtgca ggtattcctt tgtccttatt
    17101 tttgacaaaa ccgattgcaa ctcctatagc aaataagata tccaagtttc caaaaacggc
    17161 atttccagct gcaccaatta ctgggatgtt cagcatatcg tcagctgata aacgcatgat
    17221 caatcccgct aatggcatcg ctgcaactgg aagtagcatc gctcttccaa gcttctgcac
    17281 atttgattta acattcattt ttattcctcc tctattaaat atcctcatat gttactaact
    17341 caatcaaagg atcatttttc actttttgag caaatgctga atgaattaaa aattcgactt
    17401 ggtgggtacg aggatacaca aaacttgaac catttaacaa ttcctgatcc aaatacgctg
    17461 cgtgacacat gacttcgatc gttttatctt ctctcaatat catgagtaaa cttgccaaat
    17521 attcttccac actcgtattg atttgtcgtt ttttttcatc agtttctcct acgacatcga
    17581 aacaaggctc aaaataatcg acatgacgaa cttcatcttt tcgttcaaag ttgctccgaa
    17641 ccggcaaatc atattttttt gctaatgtaa caactacctc ctgattttca tccaaagtat
    17701 gagtatgatg atgactgtct aaatgagttg gtatgatccc cgcatgataa attttttgaa
    17761 tctgagcatt ccattcctga tacagttgat ctttgtcaat gttaaatgga tgctgataat
    17821 aagataagga tctgaactct ccgctttcga taagagtatc gacagttttg aggagtggtt
    17881 tgccacacgt caatgttaaa tggactccta cacctagcct aggcatttcc tttcttagtt
    17941 tcacagcatg ctcgaaaccc ggcatatttg ccatcaatgt agttgatgtc aaaattcctc
    18001 gctgataagc atccataatc ccataattca caccatggct atagccaaaa tcatccgaat
    18061 taaaaatcac ttttcccatt tcattctcct tcttttttct actaaaatag gcgcaaccaa
    18121 ataatcatag tccatttact atgtgtcatt tggttgcgcc tatagatagt tacgccctta
    18181 ttttaataga ttcttgctag atgaattgcc aaatagatga tttcattttc ttgaatggca
    18241 agttgaaatt gctgttcgat gatatcttta atctttagtg ctgtacaata cgctttgcta
    18301 tgtttaaatg tttcagtaaa aaaaccaata ttttctactg gcgtttcttc ctgataaatc
    18361 aagcgtttaa ccaggaattt gatatgaacc attaagcgat gataagtcag tgattcttta
    18421 tcataaacgt ttgaatagga tttttctaga tgggacaaaa tcgtggtcgt catttctact
    18481 atttttaagc tctttaaact attaggctct cctagctcag cattaatgat atgcatagtg
    18541 atgaatccta cttcatttga ccctaactcg gtttgatatc gatgattgat tcgctcgacc
    18601 acttctactg ctatatcata ttcatttgga taaaggaatc tcatttctgg caacataatt
    18661 gctgtgacat ctctatcttc tctttttcgt tgaatagcaa aataaatatg atctgtcaat
    18721 gtaatataga tatttgaatc taatggagag gagatcctag ctgttatcag ttcaatcact
    18781 tcttccgcaa aatccataaa ttcgattgga atctgcgaga ctatctcact gaatcgtttg
    18841 atcttttctt tagaatctaa tacaaataat ttgtcagcat cctcaacatc aaatggctta
    18901 ctcactttag cagaaaagcc aatccctttc cccatcgcaa ttttttctat tccatcgtca
    18961 tcgatcaata cagcattatg attcagcttt ttcatcacat acaccgttaa ttcacctcct
    19021 ctatatgata aaacaaaaca acttgcagac tccttcatac atatttttgt ctccaaacaa
    19081 tttttaaaga caaaaaacga cctaagaaag aaccctttct taggtcgtgc ctaattgaat
    19141 agtagcaccc tacataattt acaaaaatag tttaacacat aataaaagcg ttatcaatat
    19201 cttttttact cgttttatga taatacttgt atcgaattga tttggaggta attacataaa
    19261 aacaaaaaaa atatagcaac tctctataag aaagttgcta tattgataat tataccggcg
    19321 gccggggtcg aaccggcacg tcctcaacgg acactggatt ttgagtccag cgcgtctgcc
    19381 aattccgcca cgccggcaaa tttaaaaata ataactgggg tagctggatt cgaaccaacg
    19441 catgagggag tcaaagtccc ttgccttacc gcttggctat accccaagaa taaagggcga
    19501 atgatgggaa tcgaacccac gaatgccgga gccacaatcc ggtgcgttaa ccacttcgcc
    19561 acattcgcca tcataaaaga tgttatttaa tttctcaata aaaaactaag atgaagacat
    19621 cttagtcaat accggcggcc ggggtcgaac cggcacgccc tcaacgggca ctggattttg
    19681 agtccagcgc gtctgccaat tccgccacgc cggcaagttg atttattagt actaaggcgg
    19741 taaccggatt tgaaccggtg atgaaggttt tgcagacctc tgccttacca cttggctata
    19801 ccgccattat actattatca atctataaaa taaagaataa attatagaaa ctggggtagc
    19861 tggattcgaa ccaacgcatg agggagtcaa agtcccttgc cttaccgctt ggctataccc
    19921 caagaataaa aagggcgaat gatgggaatc gaacccacga atgccggagc cacaatccgg
    19981 tgcgttaacc acttcgccac attcgccatg gcaggggcag caggaattga acccacacta
    20041 acggttttgg agaccgctgt tctaccttta aactatgccc ctataaaatg gaggagagtg
    20101 gattcgaacc actgaaccct aaggaacgga tttacagtcc gtcgcgttta gccacttcgc
    20161 tactcctcca tggtggcgcg ggacagaatc gaactgccga cacacggagc ttcaatccgt
    20221 tgctctacca actgagctac cgcgccatat tttaaaatta ttaattgaat aacaagaacg
    20281 acggttccga cgggaatcga acccgcgatc tcctgcgtga caggcaggca tgttaacccc
    20341 tacaccacgg aaccagttca ttatggaggt taacgggatc gaaccgctga ccctctgctt
    20401 gtaaggcaga tgctctccca gctgagctaa acctccaaca ttcaattaaa atgacccgta
    20461 cgggattcga acccgtgtta ccgccgtgaa agggcggtgt cttaaccgct tgaccaacgg
    20521 gccaggtaaa tttgctacgg agagtaaggg attcgaaccc ttgagacagt ttggcaccat
    20581 ctacatgatt tccaatcatg ctccttcggc ctctcggaca actctccaga gtgaaagaag
    20641 ctcaatactc tttctcaaaa tgagaactcc ggcagtagga ctcgaaccta cgacatcatg
    20701 attaacagtc atgcgctact accaactgag ctatgccgga ataacat
//
LOCUS       DACGEU010000049        20186 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.049, whole genome shotgun sequence.
ACCESSION   DACGEU010000049 DACGEU010000000
VERSION     DACGEU010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20186)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20186)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20186
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.049"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            212..1018
                     /gene="proB"
                     /locus_tag="IXR40_001689"
     CDS             212..1018
                     /gene="proB"
                     /locus_tag="IXR40_001689"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HAQ4361528.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            1015..2262
                     /locus_tag="IXR40_001690"
     CDS             1015..2262
                     /locus_tag="IXR40_001690"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HAQ4361529.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVTGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            2338..2682
                     /locus_tag="IXR40_001691"
     CDS             2338..2682
                     /locus_tag="IXR40_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361530.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(2799..3125)
                     /locus_tag="IXR40_001692"
     CDS             complement(2799..3125)
                     /locus_tag="IXR40_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361531.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(3498..4700)
                     /locus_tag="IXR40_001693"
     CDS             complement(3498..4700)
                     /locus_tag="IXR40_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAQ4361532.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
     gene            4817..5332
                     /locus_tag="IXR40_001694"
     CDS             4817..5332
                     /locus_tag="IXR40_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAQ4361533.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(5531..5977)
                     /locus_tag="IXR40_001695"
     CDS             complement(5531..5977)
                     /locus_tag="IXR40_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HAQ4361534.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(6024..7502)
                     /gene="msr"
                     /locus_tag="IXR40_001696"
     CDS             complement(6024..7502)
                     /gene="msr"
                     /locus_tag="IXR40_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Msr family ABC-F type ribosomal protection
                     protein"
                     /protein_id="HAQ4361535.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(7856..8485)
                     /locus_tag="IXR40_001697"
     CDS             complement(7856..8485)
                     /locus_tag="IXR40_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HAQ4361536.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGVEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            complement(8469..8933)
                     /locus_tag="IXR40_001698"
     CDS             complement(8469..8933)
                     /locus_tag="IXR40_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAQ4361537.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(9420..10688)
                     /locus_tag="IXR40_001699"
     CDS             complement(9420..10688)
                     /locus_tag="IXR40_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosaminidase"
                     /protein_id="HAQ4361538.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(10919..11656)
                     /locus_tag="IXR40_001700"
     CDS             complement(10919..11656)
                     /locus_tag="IXR40_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAQ4361539.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(11723..12292)
                     /locus_tag="IXR40_001701"
     CDS             complement(11723..12292)
                     /locus_tag="IXR40_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HAQ4361540.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLLVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            12420..13292
                     /locus_tag="IXR40_001702"
     CDS             12420..13292
                     /locus_tag="IXR40_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAQ4361541.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            13634..14506
                     /locus_tag="IXR40_001703"
     CDS             13634..14506
                     /locus_tag="IXR40_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAQ4361542.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            14503..16461
                     /locus_tag="IXR40_001704"
     CDS             14503..16461
                     /locus_tag="IXR40_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4361543.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAAARPAQTNTVVKTETFAGETIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVEEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(16712..17563)
                     /locus_tag="IXR40_001705"
     CDS             complement(16712..17563)
                     /locus_tag="IXR40_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAQ4361544.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKELEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            17686..18153
                     /locus_tag="IXR40_001706"
     CDS             17686..18153
                     /locus_tag="IXR40_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HAQ4361545.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(18416..18898)
                     /locus_tag="IXR40_001707"
     CDS             complement(18416..18898)
                     /locus_tag="IXR40_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAQ4361546.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVSA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(18998..19861)
                     /locus_tag="IXR40_001708"
     CDS             complement(18998..19861)
                     /locus_tag="IXR40_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAQ4361547.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGDRLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYGLVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
BASE COUNT         6070 a         4157 c         3663 g         6296 t
ORIGIN      
        1 aaactactcc tattctaaca tatccgaggc tgtaaaagac tttctttaca aattcttcaa
       61 gaaattctgc tatcttaaag taaaccatta attcgttctt tttccaaacg actacaagtt
      121 gtacaaaaaa actatttttt acatgacttt actcgtcaaa acaagtagaa tagaacgaaa
      181 ttaatgagtg gatatttgat tgaggtgtca catgcgtaaa gaaattaaaa atgcaaaacg
      241 aattattgtc aaagtaggaa caagtacatt gatttatccc aatggaaata tcaatcttgc
      301 ggcaatcgat cagttagctt ttgtcctttc tgatcttaga aatcggggaa aggaagtgat
      361 cttagtctca tcaggagctg taggcgttgg tatgcataaa ttacatttgt cagaacgtcc
      421 gactttgatt cctgaacagc aagctgcggc ggctgttggt caagccgaac tgatgaatat
      481 ctataatcaa agattcagtg tatataatca acagacggca cagatcctcg tgacaagaga
      541 cgtggtagat tatcctgaaa gtcgtaaaaa tgtgaggaat acattggaac agcttttgat
      601 tatggacacg atccctatcg tgaacgaaaa cgatactgta gcagtggatg aattagatca
      661 tctgacaaaa tttggcgata atgatcagct gtcagccatc atggcaaaac ttgtcgcggc
      721 agaccttttg atcgtccttt ctgatatcga cgggttttat tcagataatc cgactacaaa
      781 tcccgaggct cagatgtatc gctatatcga taaaatcgat gaaaagattc tggcacaagc
      841 aggtggtgct ggtagcacat ttggaacagg cggtatgcag agtaaattaa aagccgcttc
      901 taggatattt gaagcaaaca gcgcaatgat tttagcaaat ggaaaaaatc cggcaattat
      961 ttttgatatt cttgcaggaa aagaagtagg tactttattt aaggaggact tgaaatgact
     1021 gacttgatgc aattaggaca acaggcaaaa gatagcgcgc aacaactagc acttatgcct
     1081 acaaaccgca aaaatgagct acttgttcaa atggcacaaa ccatcaaaaa gaatcaacaa
     1141 gcgatcattg aagcaaatca taaagactta gaaaaagcag tcgaaaacaa tatcagtgaa
     1201 acgatgcaag accgcttgca gctgacacct gagcgaatca atgccatggc tacagagatc
     1261 gaaaaaattg cttcgttaga cgatcctatt ggaaaagtag atgagatgtg gacgaacacc
     1321 gacggattga gaatcggcaa aaagcgcgtg ccactaggcg tgaccggcat catttacgaa
     1381 tctcgtccaa atgtcacgac agatgcagct agtctagcat tcaaatcagg gaatgccgtt
     1441 atccttcgcg gtggcaaaga agcattcttc tcgaatcaat tattagtcca attattgcag
     1501 caagtactgg tcagtgctgg cgaatctcct tatgccatcc agtttgtcga tgatacttct
     1561 catgaaactg caggacagtt gatgcgattg acagaatact tagatgtgct gattcctcga
     1621 ggcggagcaa aattaatcca acgagtcaaa gaacaggcaa cggtacctat cattgaaaca
     1681 ggtacaggaa ataatcacgt atatatcgat aaagaagcac agttatctat ggcagtgaac
     1741 atcatcgtca atgcaaaagc ttcccgtcca tctgtctgta acgcggcaga aacattgctg
     1801 atccattctg agatcgcacc ttttttcttg ccagctattg aaaaagaact ggtagaacac
     1861 ggggtctctt tacgtgcgga tgctcgtgcg ttagaatatc tagagacggc tgctttagca
     1921 gaagacacag attgggatac tgaatatcta gattatatcc ttgctgtcaa agtggtcgat
     1981 tctttggatg aagcaattgc acatatcaat cggcataata ctaaacattc agaaacgatc
     2041 gtgacagata gttatgcggc tagtcaacgt ttcttaaatg aagtggacgc ggcggctgtc
     2101 tatgtcaatg cctccactcg ttttacagac ggatcggtat ttggttttgg tgcagagatt
     2161 ggtatctcta ctcaaaagtt gcatgcccgt ggtccaatgg ggttaaatga attaacttcc
     2221 acaaaatata tcatttatgg cgatggacaa atccgcgaat aatgtttcgt gtgaaacatt
     2281 attcccgcct tttgcctttt ttctgtaaag gttctatcca actagaaagg tgtcaatatg
     2341 tttgaaattt taatgatttt ttttatttac cttatttctc tgaatatcgc tgcttttctg
     2401 ggagtcggta ttttatccct tttctttcaa ttcaaaaaac gaagcatagg gagtcaacgg
     2461 gaaaaatggt cgcagtattt tgacaaaatc gggcaaaaag ggctggttac acgcttgcac
     2521 attagttaca tggttgcatt atgcttatta gcgacaatca attactattc ttttttcgat
     2581 cattcaatcg cttatacgat tacgctactg attgctggga tttttcactt atcttataaa
     2641 tatcagctga ataaaaacca cttgaatcgg actttccgct aaaaaatatc cgtacgataa
     2701 gtagagtgcc ttgaagatcg gcaaaaaact gccggacttt ttagaggctg tgacaaagat
     2761 tttgtcacag cctctttttc catataaacg gcgttcgcct accagctgcc tggtaaatct
     2821 gtttcctctt cgttaagaag cgaaaatccg tcaaatgttt cgccatcata ataacgaagc
     2881 agctcatcca tggacaagtt catcgttttt tctttttctt cttccgctga ttcagccagt
     2941 agctgttccc gatacacctg atacatacca gctatttttt gctgcatcgc ttttctagtt
     3001 tcaccttccg cattgattat tggcaattct ttgatatagc cacgataaat caaccgatca
     3061 tctgaaaatt caatgggtaa ttcaacgagt gtcaacccga cttcctgaaa atattcttcc
     3121 agcatctatt atccccccat tctttttctt aaatgaattt tagcttacct actgaaaatt
     3181 ttccagtttc attattttga gaaaaaaagg gaatgtgaca aaaatcgtgt cacatcccct
     3241 ttttccgaat aaatggtgtt cttctgccaa ctcctcaatc ataagtcaca atattcaaca
     3301 aacatgagaa actgtttttt gaaattgttc cttgtgattc agagttaaac gacagtctca
     3361 caacctcttg gtaaacggcg ttcaaaagct tgcatctgcg gtaataagcc caaccaaacg
     3421 aaaaatatga gaagctattt ttgtttggct gttcttatga cttgatgcag gacagctttt
     3481 tcacaacctc tgatttctta ttcttcttca tttgtagcaa aataattacg gtgataaatg
     3541 atacaacata cactgataag aacaatggca cctgcaaaat aaaacgcata gctttcacca
     3601 atatgttcac caatcacacc tgcaataaat ggtgctaaag ctccaccgaa aaagcggaca
     3661 aaactatagc tggacgaagc aacgtttcgt tgcagacctg gtatttccat agcaatcgtc
     3721 gtcaacagtg tattgataat tccttggaaa aatcctgcta acacaatgct gatcggtaca
     3781 aggactggca tagaagttcc agctcctaat aacagcaaac aaataatgaa taagacaaat
     3841 gctgctaaaa ttgtccgata agtcgtaaac ttccgctcaa gagccggtgc aacgaaaatc
     3901 gaagcaatag ccagaagcac accccagcca aaaaatacaa aaccgacttc taattcagaa
     3961 tagccaatca ataaaaatgg cgcatacgca agtaaagtaa agaatccgaa attatataac
     4021 aatgcgatta gtccaactga acgaagttta tgattgctta acgctttgac accttcccaa
     4081 aggcctactt ttctctttgg tttctcagtt tcaggtaaaa gtaccgctag ggctataaaa
     4141 ccgcaaaaca tcaaaaatgc taccccaaaa aatggataac gccatgaacc actgcccaag
     4201 accccaccga ctagagggcc aacagccatt ccgcagccaa gtgctgcttc atacatcatg
     4261 attgcttttt ctgtgttacc aactaaaata ctgacgatcg ttgctaaagc agtagagaca
     4321 aataaagcat tcccgacacc ccagccggca cgtaacccaa tcagcattcc gatattccca
     4381 gataatccgc caagaccagc gaatacaacg atgataaaca atcctgtcat caatgttttt
     4441 ttcaaaccga tccgactaga taagaaacct gtaaatagca tcaccacacc agtgactaac
     4501 atgtaactag taaataacag ggtcgtttca gctggcgtag cgtttaactg tgcagcaatc
     4561 gtttttaaga ttgggtctac tagacccact cccataaaag cgatcataca ggtagctgct
     4621 acaactagcg ctgaactttt cccctttgtt tcttcatttg tttgttcttg tatatctatt
     4681 tgattctcca atatttccat ccctttctct ctattagcat catacatgat ttattttaca
     4741 tgtaaatatg cacatgtaaa acgtggaaac tttactgtga tataataaag aaaataagac
     4801 gagaggtagg atttttatga atactttagc ctatatatta ttatgcgtgc ttttatccaa
     4861 accacgttct gggtatgaat tgaagcagct gatcacaatt ttttgggaag cccatcacag
     4921 tcagatctat acaacgcttg ccaagttaga ccagcagggt tatgtgaccg ttttggacaa
     4981 agacgagcac tctcaaaaaa agatctacca cttgactgat gaaggacgtg ctcttgtaga
     5041 ggaatggatc aaagaggaaa ctcccgctcc tacgcaaaaa gatgaatttc tagcaaaaat
     5101 ctatgctttt tcgacgctcg ataaaacaac agctactgga ctgctattca ctagagaaca
     5161 acagctgaac aaaatcatgc aaaaaaatca aaaaaaattg aatgacctct cgctagacaa
     5221 gaaacaagaa tttggacgtt atgttgtgat ccagcgcaga attatgcttt gtcagcagga
     5281 actccaatgg tgtcagcaag taagagaaca aatgcagcag ttttttgagt aagggataaa
     5341 cagaaccttt ctagaaatat ctattgaaga gcaaattatc ttcaataaaa gagcaataca
     5401 gttggaaaag aaaaagcgat ccgaacgaca ggccaaaacc tatcgttcgg atcactattt
     5461 ttctagaact gcattcaaga gactatgaca aaaagcatgc caaggccttt tttcaaataa
     5521 cagtgttcca tcattcatta ctttgaattg cttttagcac acttcttgaa agcgggccaa
     5581 cgatgatcaa ctgcaacggt aaagcggcaa tcacattcat tttccaagca ttcatataag
     5641 cagagaataa ttgatcaggt attccttgtt ccatgatcac accgaataaa gacatacatg
     5701 tcaccattcc taaaaccatc aagcatgaaa tagttaagat catttggacc ttgctttctg
     5761 gatttactgg tagtttaaag gcaatttttt tcgccagcac accgatgatg aagacatcca
     5821 aaatgaaagc caccacgaat ccaggcacta gaccaatcaa caaacttgat aaatgaagat
     5881 cttgatgcag ccataaatta tacgcgctca tccccaagac catcaaaaaa cacatcattg
     5941 ttgtaaaaat tattccttct tttttatttg taggcaatct gtaccactcc tttaaatttg
     6001 tcacgaaaat catcgtagca catttaaaaa tttctcgtaa gtactttttt tattttctgc
     6061 ccttttattt cataaacttc atcagccgta cgctcgacaa agtaagaatc atgagaagta
     6121 aacaaaatcg ttcccggata tatttgcatt agcttctcta aagcttcgat cgttgccata
     6181 tcaataaaat tagtcggttc atctaacagc aacacattac ttggcttagt aaaaagcaaa
     6241 gcaatcgtca gacgggtcgc ttctccccca cttaatgtac ataacggttt cgtcaaagtt
     6301 tcctgagcaa accctaagtg attcagcaaa ctacggacaa gcgattctga aaactctgtt
     6361 tgtctcatga caaaacgaat gatggattct tcagatgtca tttgataacc cttttgctga
     6421 tatacttgaa agcttacttt cggagagaga aggattcctt ctccttgttt gcggatatgt
     6481 tctaataagg ttgtcttacc tgaaccattt tcaccgacaa tcgcgatttt tttacctaaa
     6541 gaaaactgaa aatcaccatt taccagtaat gttctcccac ttctttccaa ttggacattt
     6601 tgtcccatga tgggatagcg gctgtggagt tcaagagatt ttggtactgg aaaacggatt
     6661 tgtttcatct gctgcggctt ggttgtttct cctatttttt ggagtcttct ctctaatgtt
     6721 ttcgcattct tttggatggc tttttgtaca ctgtcttttt gtttagagga agacaaccga
     6781 tccggtctga tttgttgctt tttcttttta ctggacactt tttccaactt ttccgcttgt
     6841 tttttctttt cttggatcga tttttccaat cgttttttct ctttcatgat cgactctgct
     6901 tctcgtagct gagtcttttt ctccaattcc ttttgagtga gataggcact ataattcccc
     6961 gaaaactctc ggatttctcc gtcttttact tcccagattt tcgatgctag ctcatctaga
     7021 aaatagcgat catgactaac aaaaaccagc gtaccataat aataacgaag ctcttcaatc
     7081 agtcgatcaa tactttttct atctagatgg gttgttggct cgtctagaag catcccttgt
     7141 tcataagaag aaagaagacg tatcaactcg atctttcgtt cttcccctcc gctccatttc
     7201 cgctctgaag tttcttccag tcttaactgg aaatgactgg ctaattccaa atttaggtcc
     7261 tttgcttcag cgagataggt taattgaggc aggtagttga aggtgatctc tgtttggatt
     7321 ttcccatgat cgggaaaaag ttcaccggct attagtttga gcaaagtcga tttaccgaca
     7381 ccattttctc ctatgatccc tatacgatct tgctgataga cacgaagaga atcaatagat
     7441 agttctagct ggttgccaaa gctgacttgt agatttgtta tatttactgc taaattttcc
     7501 atatgtttta cactcctatt tcatgtaaaa caacaattat cgatactaaa aaagagcaga
     7561 aaaatctgtt tgcaaaaaaa ctgcatcaca tcttttccta ctctgaacga aataactatg
     7621 actaaatcac caaatctgtc atagctttca cctattctac tgtcgttcga aaaaatggac
     7681 atactccatc catgaaattg ttgtttatac atgtcttttg aatttattta gttgttattc
     7741 aaaagttcga aacgtaattt catcgatgca gtcatttttc cgacctcctt ttttattagg
     7801 ttaccacaca cgattcaaaa aaagcaatag ctactgaata gtaactgaaa accttttatt
     7861 cgaacgtagt gatcttttct ggtgctaaac gaacagactc gtaaccttct tctaccgctt
     7921 ttcctattga taaaataata actggaacat aacggtcttt atccaaacca aatgcctctg
     7981 ccaactgatc tgcttcgact ccaccaattg gatttgtttc atagccatga tcacgcgcaa
     8041 ctaacatgaa ttgcatagcc gctaagctag aatcgacttt gactacatcg ttcatttctt
     8101 ctcttgaaaa actcttgtaa taaggaatga tcgcagctaa ttgttgatct ctgacttctt
     8161 ttggcatctt ccctgattcg taagcttggt tatagatttc ttcgccatat tcgtaacatt
     8221 gcatatcgcc aaaaatcatg accattgcag aagaagtatc attttgtctc gtattgaaac
     8281 ggatcaaagg acgcaagatt tcttttgctt cctcgctttc agcgaccaca aagcgccatg
     8341 gttgcatatt gacagaagaa ggtgcagtcg tcgcttcttt gatcatttcc agcatttctt
     8401 cgtgtgggat tttgtatgtt tcatcatata cgcgaacgga tcttctacca gtcataattg
     8461 ttgaaaaatc atttttttgt tccattatta ttaacctctt tcgtttctgt tgttatattg
     8521 caaagttggg tattcaattt atctaaaagt gttagaaatt gtttcatttc tacatcgctg
     8581 aaagccgggg atagcacgga acctgtatct ttatggtcca tttcacaatg ctcgattttc
     8641 ttctgggctt tttctgttag cgctacatac acttcccggt tgttctgagg atttctctga
     8701 cgcgaaacat agccatttgc ttccaatacc ttcagatgac gagtaactgc tccttgatca
     8761 atctgcaact tttcttgcaa actgctttgt agcaatggat tttcttcttt cagtctcatc
     8821 atgatctcgt atctagtaag acttataccg atattttctt caaagatctg gacgattttt
     8881 tgatcggcta atttgatttg atataaaagg tgactaatct cttctaaaga cataatttcc
     8941 tcctttctaa taattgactc gtcaacgatt gacttgtcaa taatagaata aaaaaagaaa
     9001 aaagtcaaag aatcagctgt gtaataaaaa aaacgctctc aatagaaaag tatagagaaa
     9061 agaaattttt tgtagaatga acggaaaaaa tgataaagaa agcacaacgc taaaaccaag
     9121 attattgatt cttatcaaac tatagaagat agctcttctg cagtagaaaa ttttacaccg
     9181 ccaaaaattt ccgaaatcgc cttttgcaag aatcccgtcg aatattagaa attggatcag
     9241 tatgcttaaa cagtaataaa aaagttatga caagatgttg tcacaacctt ttttgagtaa
     9301 acggtgttca aaaacttgca tctgcggtaa taagttcaac caaacaaaaa acatgaaaat
     9361 ctgtttttgt ttggctgttc ttactacttg atgcagggca gctttttcac tacctctttt
     9421 taataaccat aaaatcctat tccttcatat ctccagccca tcggtgttag ccaatctctt
     9481 tccttagcac tcaaggtata gtgatgggta ccagtttttt catttggatt aaatagtcga
     9541 taaattggct tggaaccacc agaataaaaa cttagacctt cataacgcca accgattttt
     9601 gttaaagagt tgatctcaga ttgtgccatt gtgtaatgat ggtctccact gtaaggattg
     9661 tataaacggt agacaggttg tccgctgttt ggtgcttgcc aagcaatccc ttcatattcc
     9721 cagcctacag ttggcagata atttttttct ccggcattca atgtatataa atgttctcct
     9781 gtatgacggt tatacagacg atacatcgga gaagttgaag ttggtgctgt atcatactgt
     9841 gtcagattat aggtttcgat tacattgttc aatgtagaac cataattagg cgcagtggca
     9901 taacgacctg ttagccaagc cgtagcatct ttgtaagagt tcgtattgct tttccatgca
     9961 ccggaatagt agtaaacgcc tggctgaaaa gaagtcgtct tcaataccgt tacgttatct
    10021 tgcaatgatt ctttgtacga aggatatttt ctaaaagcgg cattcaccgt aatccattgc
    10081 ccattcacat attccgaagt aggcatcgta acagattggc cattatagct tcctttaatc
    10141 ccaaatagat tgtaattagg ggcagaagcc aaagtactgt tcccccagcc actttcaacg
    10201 atggcttgag caatcatgac tgatgcatat aagtcattgg cacttgccaa actttgtgca
    10261 gttgaggcaa tactatcaat gaacgcttgt tgagaattag cagatgagcg agcataaaaa
    10321 gcatagccag tatagttttc gaattcagac aaatctgctt gatgggtatg tgtcaatgtt
    10381 tgcccatctg tcaattggtt cgtgatttct tctgcattct ctggattgtt ctgagcttct
    10441 gctgatgtac tgtcttcggt ttgtgtttgt tctgttgttt cagttgttgg ttcttcggtt
    10501 gaaattgtat tttctgagac agtagctgac tgcaaagtac tctctgtatc gttttcaatt
    10561 cctgtttctg aagaactcga tgtctgagtt gcgacagttt ctgtcgattc ttcagctagc
    10621 actgttgtgt tggcaactgc tagatttcct aaaagaataa cgctaaataa taaattcttt
    10681 gctttcatct tttttctcct ttgaattatg aaacttttcc taaataacag tgtaactaaa
    10741 aaagtaaaag caagtcaatg tccatattta aataacattt gtttcttttt gataaatttg
    10801 ctttttctac ataaaaagac gtaaatgaag aatattcttc tccattcacg ccttaaattg
    10861 atggtcgttt gaataactat ttaacaagta attctctttg gatattatcc gttatggatt
    10921 atacttcctg tgtcgtcgga cggataatca tgttactgac agacatccgg tctggcgttt
    10981 ctatcgcaaa tgctacagca gaagctatat cttcggaggt caatccccat tctttttgcg
    11041 cttcatgaag ttcaagagca gcctttttgt cgctgatggt ttgatataat tcagtttgaa
    11101 cagctcctgg agagatgatc gtagatttga tgttattttg ccgttgctct tgacgtaatc
    11161 cttccatgat tgcacggaca gcaaattttg ttccgcaata aacggcggaa tcaggataaa
    11221 caacatgtcc cgccacagaa tcagttgaaa tgatatgccc agatttttgt ttttccatga
    11281 ttggaagtac ggcggaaatt ccatttaaca cacccatgat gttgatatca agcatatttt
    11341 gccattcatc acggtgacct tcaactaatg gagcggttgg catgattcct gcattattgt
    11401 acaatacatc gattcgaccg aacttttcca tcgctaaatc gataactgct tggacttgtg
    11461 caaaatctct tacatctgct gtttgaatat atagctcagc ttctggtaaa gattctttta
    11521 ttgcttttag gcgatcttct cggcgtgcag ctataactag tttagcccct ttttctgcta
    11581 atagcttcgt tgttgcttca ccgattccgc ttgaagcgcc catgatgaca atcacttttt
    11641 ctgataaatc attcattcta ttctcctcct gttttgaaaa atctcttgct tatactcact
    11701 atctcttatt tcatcttact gttcaaataa tccgttcgac aggtttgacg attttggcag
    11761 ggattcctgc aacgatggta ttgtctggga catctttcgt aacagttgca ttcgctgcaa
    11821 caatggcatt ctcgccaatc gttacgcctg gcagaatagt tgctcctgct ccgatccaag
    11881 catttttctt gatgtggatt ggctttacta acaagcctct tcgttctttt ggatcggtta
    11941 gatggttcac cgtgatgagg ttgacacgag gaccaatcaa tactgaatct tctaaacaga
    12001 tgccacctaa gtcaacgaac atcacttgac gattgataaa gacatttttc cctatactaa
    12061 tatgtttgcc gaaatctgta taaaaaggca gcagaacagt caccgtatca tctactttgt
    12121 cactaatgat attttctagc cgtttgcgga tatctgctgg ttcatggtac ccagtattca
    12181 gcgctgctaa aggctcttcg ttttcagctt ggatctgatg gatcacttca aagagcggat
    12241 ccgttactcg aatctcttta ttgacgattt gtttttcgat gaggcttgtc attttgctcc
    12301 ctccttttat ccttacttta taacggacgg cttatcatgt ctaatactta taaaacatac
    12361 ttaactattc cttttaacta tacttagtgg tatgcttttt taaaaacagg agggaaaaaa
    12421 tggatattcg tatactgacg tattttttag cagtagctag agaaaaaaat atcagccgag
    12481 cagcaaaatc tctgcatatc acgcaaccta ctctctcaaa acaactgaaa gatttagaag
    12541 aagaacttgg tgtgacactt ttcactcggg gctcccgaga gatacagttg acggattctg
    12601 gtcgatatct ttattcaaaa ggaaaagaaa tcttgtcgtt ggtagaaaaa acggcgaaca
    12661 atttaacaaa tgacgcaatc atctctggag aaatctacat tggcggaggc gaaactaaag
    12721 caatctcttt catttctgat agccttcatt cgttgatcaa ggcgcatcct gatatccagt
    12781 ttcatttata tagcgggaat gcagatgata tcatagacaa actggatagc ggattacttg
    12841 attttggact cgtaatcgaa ccgacaaaca aacaaaaata ccagtcattt cgactgccag
    12901 cccaagatcg ttggggactt ttgatacatc gaaatcatcc tttagcaaag caaaccgtca
    12961 tccatccgca ggaactgaaa actgttcctt tgatcatttc ccggcaaacg tcagtggaca
    13021 gtcaactagc tgaatggcta ggtttcagca tagatcagtt atcgatcgtc ggaacatata
    13081 acttattgta caatgcttct ttgatggtcg ataacgggac ttttggtgca ttagctctag
    13141 atgggatcat caatacttat gggacggaaa aaatattcat cccactcgat ccgccattac
    13201 aagcttcact gaatctcatt tggaaaaaag accagcctct ttctcctgct gctcgtaaat
    13261 ttttagatgt cctaacggag aaatacagtt aagtagagtt tttttccttc gctttcagct
    13321 ttttaacaac gaataagata agcaaaagat ccaacgatta aataacataa gtttcttaat
    13381 ttatttcttc cttttatttc tgataattcc agtaaattac tataattata aaaaaagaat
    13441 tgacaaaaca taactgtcta tataaaattg attacgttaa caataattcg tttcatgtga
    13501 ctagatcata ctaggcatga aaaatctctg aggaacatgg tttccctagg aggtttttcg
    13561 tgtctatttt tgtttggccg caatcaactg gtctagcaaa cgtgaaaacc aaatcttcaa
    13621 aaagggtgcg cgcatgaaaa tcaaaaagat ctttaatcaa aatgcagtat tggtagatga
    13681 cggtggacag gaaaaagtag ctattggaaa agggattgga tttgacagaa aaagaaatga
    13741 tttgattttt gatcgtgatg tcgaacggat atttgtcatg gaaccagaag gtcaaatcaa
    13801 gttgcaaaat ttacttaatc agattgatga acgcttttta tttgcagcag aaacgatcat
    13861 tgatcatgcg gaaactgttt tgatggaaaa gttgaatgaa catgtattga tcgctttgac
    13921 cgaccacatt gctttttctg cggagaacat taataacggt atcgtcatcc gcaacaaact
    13981 tttaagagaa atcgaagtgc tttacagtga tgaattcagt attgctcaat gggcagtaga
    14041 gtatctgaca aaagagcttg ggattccata tacttatgac gaagcaggat atatcgcaat
    14101 ccatattcac agcggacgaa gcggtcggaa caataaccat cgcagtatcc gtgaagtgac
    14161 gattgtatct gacatcatcc atttagtgga atcagaattg gaaacagata tccattcaga
    14221 accattttca ctgaattatt caagactggt gaatcattta cgactgcttc tacaacgaac
    14281 ccatgcgcaa caatatgctg ttttagacac ggaaatcgta gaaatggtca aacgaaaata
    14341 cccagaaagc tataagattt ctaaaaaaat ccgtgtgttg ctgaccaaag aataccagct
    14401 cgcgatcacg aaagaagaac tgggttactt ggccatccat atcgagcgtt taagaagcgc
    14461 aatcgtacaa acaaatgtta acaatcatga ggaggaaaaa aattgaaagc atatctacaa
    14521 cgaatgggac gttcccttca acttccagtt gcggtcttac ctgctgctgc tttactagta
    14581 gggatcggaa actggtgggc atcttatagt aacgacattg tcgctcattt tttacaagct
    14641 ggcggtaacg cagttttagg tcaattacct ttgctgtttg ccgttgggtt agcactaggg
    14701 atgtcagtgg acaaatcagg tgctgctgcc ttggcaggtt tggtcgcatt tgaagttcca
    14761 gtaaatgttt taaaaactga ttcagtagct actttattga atatcaaacc agaatcagtt
    14821 gatccatctt ttgctcagat cagtaacgta tttattggta ttattgccgg attgattgcg
    14881 gcagctcttt ataatcgttt ccacgaagca aaattaccga tggctttatc tttctttagc
    14941 ggcaagcgtc tagtgccaat cttggctgcc tttgtcatgt tgctgatcag tgcagtgcta
    15001 ctgctcgtat ggcctccggt ttactctgct ttagtttctt ttgctaaatt cattttgagt
    15061 ttaggctggg gtggtgcagg tctttatggc ttcttcaacc gtttactgat ccctacagga
    15121 ttgcatcaag caatgaactc cgtgttctgg tttgacgtag caggaatcaa tgatattggt
    15181 aaatttttgg cttctgaagg aacaaaaggc gtaacaggaa tgtatcaagc tggatttttc
    15241 ccaatcatga tgttcgggct tccagcagga gcatatgcta tttacagaaa tgcacgtcca
    15301 gaaaacaaag caaaaacagc ttccttgatg ctagcagcag cttttgcttc attctttact
    15361 ggtgtgacag aaccacttga attttcattt atgttcgttg cttggccatt atatgtcttg
    15421 catgcaattt tcactgggat ttctttagca gtgagtgcat tcttccattg gacagcagga
    15481 tttgccttta gtgccggatt tgtcgattac ttcctatctt tgaaaaatcc gattgcgaat
    15541 cagccattga tgttgatcgt ccaaggatta gtaacagcag tgatttacta ctttggcttt
    15601 aactttgcta tcaaaaaatt ccatctgatg actcctggcc gcgaggaagc agatctttca
    15661 gatgacgata ctgcaacgac taattcagac aataaatatg cggcacaagc aagcaaaatc
    15721 tacgctgcat taggcggagc cgacaatgta acttcgatcg ataactgtac tacacgcctt
    15781 cgtttgcaag tcaaagatac aggcctgatc gatcaaaata aaatcaaagc cactggcgta
    15841 cctggtatga agatcatcga cggaaaaaat gcgcaagtca tcgtaggtac agaagtacaa
    15901 ttcgttgcag atgagatggc aaaactacat ggtggtgctg cagcacgacc tgcacaaaca
    15961 aacaccgtgg ttaaaacaga aacatttgcc ggtgaaacga tcgaacaaga tatttacgct
    16021 atcgcaaatg ggaaactgat tccaatcact gaagtttcag atgatgtatt cgcggaaaaa
    16081 atgatgggtg acggctatgc tgtattacca gaaaatggag aaatcttctc tccaatcgct
    16141 ggtacgatca caaacatttt cccaacgaaa catgctgtcg gaatccaaac agatgctggt
    16201 atcgaagtct tgcttcatat gggcatcaac actgttgact taaaaggcga accattcact
    16261 ttatatgtag aagaaggtca aaaagtcgca agaggtcaat tgattgcttt agttgatctt
    16321 gccgctattc aatctgcagg caaaaacacg gatatggtcg ttgtattcac aaatggcgac
    16381 aaagtccaaa gcttagaaat cgaacccgca cgtgatgtaa aagcaaatga taaaatcggc
    16441 tctgtttcca acaaagcctg agccatcgtc ttccccagac ttttttatcg ataaacaaac
    16501 aggagctgag acaaaaatct tgtctcagct cctttttccg aataaaaacg gcgttctcct
    16561 gccaactccg cggtaataag tccagctaaa cgaaacatat gaagagctat tttttatttg
    16621 actcttctta ttacttgatg cagaacagct ttttcacaaa atttttcttc atactcaaaa
    16681 ctaatcggct ttttcacaac ctctttatac attattcctg atccaatatt tcttttaatg
    16741 ctgcttcaag agaagttaat ggttttccca atactttttc taaatcatca gaggaaatag
    16801 ctaactgatc ctttttaata tcatgttgga tcgctaaaaa catgtcagct gcttcttgag
    16861 ggaatccggc ttcttttaga ttttcgacaa acgctgcatc acttgcttca ataatttcta
    16921 actctttacc tgtcgcacgc tctaatgcct tggctaattc ttcatagtca gttagattgc
    16981 cggataattc taagatttct ggagagtcac tttctactag tacttttgct gcagcttctg
    17041 catattcacg tttcaatgcc caacctgttt ttccatttcc tgcagcataa acgaattgac
    17101 cagtttttaa agcctgccca atgataggta attcattctc tacataccaa ttattccgta
    17161 aaaatgtatg ggaaatacct gaatccttaa tcattttttc agtgaattgg tgatctggcg
    17221 ctaatacact gatcgagtga tcggcatctg caaaacttgt ataagcgata taagataccc
    17281 cagctgcttg tgctgccttc actacattct tatgttcggc ttgacgattt cctggaacgc
    17341 cagagacaaa aagcaatcga tctattcctt tcaacgcttc tttcattgag tctaaatcat
    17401 cataatcacc aatacgtata ttaaatccag cttctttcag tgcttctcct ttttcttcac
    17461 tacgtactag tacatagatt tcattttgtg gaaccatctt ttttaagaat tccagcgcat
    17521 aaccaccaaa acctccagtt gctcctgtta ctaaataatg catatttgcc actccctatt
    17581 ctttttattt gttaagattt acagctgtac atttataaat tacaccttta tcataaagag
    17641 tgtggtaaga taagtcaagc aaaaaaaatg aaaggatgac aactgatgaa gtattctctg
    17701 caatttagtg atgcaatcca tgtacttgcc tatattgaaa tgtttcaaga tacccgatca
    17761 ctttctagtg agatgattgc cagtagtatc gaaacaaatg cagcaaatgt acgtaaaatc
    17821 atgagtcagc tcaaaaaatc cggtttgatc tttacaaaaa ccggaaaacc gcagccttcc
    17881 cttgccaaaa gtccagatca gatttcttta ctagatgtct atcgcagcat cgaaggtaat
    17941 acacagctta tccaagtcga tccaaaaaca aatccaaatt gcgtcgttgg tgcgaatatc
    18001 caagaagctt tagaagaaag ctacgctcgg ctgcagaaaa aggcagaaga agaaatggct
    18061 aagatcacac ttgatagtct gatacataaa atagccgttt tggaaaaaga aaaaagacca
    18121 gaaaacacag gcctcgtaga gagattttta taattctctc tactgtgcct gcatttttct
    18181 gatcggaatc gtctacataa attcttttat tctccggggg acaaaagcct tgtcatgccc
    18241 ctttttcctc tctaatgctc aggtcaaagc gctgaagtca tgacgtcttg ataaacggtg
    18301 ttcaagtagc tgaccctcgg cattagttct gaaaaatgca aaatatggaa agctatttcc
    18361 catttttcct ctctaatgct caggtcaaag cgctactttc acgacctcta tattatcatg
    18421 gtttattgac taccggtatc cagatttctc ccatatattt cccgttggta actcccattt
    18481 cgactacagc atttggaccc ccaacatagg cgtaatcttc tacttctctt aaaacatgcc
    18541 caaaggccgt attcgtcaaa tcatttctta attcttcagg cgattctgct aaagcgctta
    18601 caacaagata cgttcctttt gggaatggga tgattcgcgt agtgtttgga acatcctgac
    18661 tcgtttgaac accgacatag tacatcattt tcccgttata gggttcgttg actgtaaaga
    18721 aataatgatt ttcagcagct tgtttcaatg catctattgt tccattaccg ataacttttt
    18781 gctcaaatgc ttgtttctct gcagccaaac cgacaaaatc cgtattgcta ctcttcaatt
    18841 ccacaccaat acccgtcacc gtaaaatctg gtttttcttc gatcctatac tttgccattt
    18901 ctcccaccct ttctattata ttaagttcat cttacataaa attaaaggga aatgacacga
    18961 ttacgctctt ttttctaggg atatttttat tttttaacta tttttttgct ttcactgcaa
    19021 tccaaatctc actgtaaaca ttactgaaat cctctcccca ttttgtaaaa gagatctcgg
    19081 gagcttcgac taacccataa tctgaagaag gaagccattc tgcatagatt ttcccccaag
    19141 tatcttgtaa agtttgggga aatggccctt tattaggaaa aatggcccaa gtgtgttctt
    19201 ctatagcaag catttctaaa tcagcgtacg gattttcttt tgtcgtagca aagccaatca
    19261 tgtgcatcaa actgcccttt tcttccaagc ggtctccatc aaatccataa gaaacgttga
    19321 ttacttgatt tggatataaa tctcctaact tatgcatctc ttccctttga gtctccgtga
    19381 tcgtctgcgc taacttttgt atttcttgat tgactccttc aaatttgaca ggaacttttt
    19441 tcgccacacc tgccacataa aactgttctt tcttttcgat acgaaattcc atcgattttc
    19501 ctcctctgac atcaataaaa aatgtcaagc gtggaaaaga tttttgtatg ccgtatctgc
    19561 tgatttctga aggcagatat cctgaccaat cacgaaaagc tcttgaaaaa ccttcgactg
    19621 tttcatatcc atatctaaac gccgtttctg tcactcttga tccatctaga agatcgcgat
    19681 tagccaaagc caatctacgg tttttgatat agtccattag cgacatccct gcaataaacg
    19741 taaagatgcg ttttaattga tattcagaga ttcctgtatt ttcggctatt attttatagg
    19801 aaagtccttc tgtcaaatgt tcttcgatgt aatcgatcaa ttggttcaga tctttaagca
    19861 tatttatctt cctccttgat tgccttttta tcatattatc aaagaaagtc aattacttga
    19921 tgaatcagga accaatttag tcagatgtag aaaatgttgt atggatctaa agaaaattct
    19981 caagcagcgt ttcgtaacgg ataattggta ttatctgcct atctatgttt tacctttaga
    20041 aaaataaatt ttggggaaga cagattctaa gtaaacaaag cggtaaaaat atcttttatt
    20101 cccttagtta atccgcttac tacctactgt acaaagcaaa ttgttgttca aactgctgat
    20161 cagaacgctg cttggatttt tctttg
//
LOCUS       DACGEU010000050        19507 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.050, whole genome shotgun sequence.
ACCESSION   DACGEU010000050 DACGEU010000000
VERSION     DACGEU010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19507)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19507)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19507
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.050"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(460..1089)
                     /gene="udk"
                     /locus_tag="IXR40_001709"
     CDS             complement(460..1089)
                     /gene="udk"
                     /locus_tag="IXR40_001709"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HAQ4361548.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
     gene            complement(1173..1868)
                     /locus_tag="IXR40_001710"
     CDS             complement(1173..1868)
                     /locus_tag="IXR40_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="noncanonical pyrimidine nucleotidase, YjjG
                     family"
                     /protein_id="HAQ4361549.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            complement(1881..2597)
                     /locus_tag="IXR40_001711"
     CDS             complement(1881..2597)
                     /locus_tag="IXR40_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HAQ4361550.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            2927..3532
                     /locus_tag="IXR40_001712"
     CDS             2927..3532
                     /locus_tag="IXR40_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HAQ4361551.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEESTGEGGEPEVIGSTEE"
     gene            3857..4180
                     /locus_tag="IXR40_001713"
     CDS             3857..4180
                     /locus_tag="IXR40_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HAQ4361552.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            4362..5732
                     /locus_tag="IXR40_001714"
     CDS             4362..5732
                     /locus_tag="IXR40_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HAQ4361553.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(5862..7163)
                     /locus_tag="IXR40_001715"
     CDS             complement(5862..7163)
                     /locus_tag="IXR40_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HAQ4361554.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYHYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKIE"
     gene            complement(7393..9384)
                     /locus_tag="IXR40_001716"
     CDS             complement(7393..9384)
                     /locus_tag="IXR40_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter Kup"
                     /protein_id="HAQ4361555.1"
                     /translation="MATTHNTKKISMAGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGL
                     SGINPDFVIGSVSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLII
                     PAMIGGAALLADGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFM
                     VQRFGTDIVGKAFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKL
                     GLFILGNIFLATTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQN
                     PEAQQIKNLNPFFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPR
                     LKIMYPGNSIGQMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALL
                     YFYLIQNGHSRWLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWE
                     QGNIIRESSTEDVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSI
                     LDKRPKRARVYWFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQ
                     VIHDLMKQGRLPKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAI
                     KKIATSPETWFGLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            complement(9528..9794)
                     /locus_tag="IXR40_001717"
     CDS             complement(9528..9794)
                     /locus_tag="IXR40_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAQ4361556.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            complement(10304..12430)
                     /gene="pnp"
                     /locus_tag="IXR40_001718"
     CDS             complement(10304..12430)
                     /gene="pnp"
                     /locus_tag="IXR40_001718"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HAQ4361557.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            complement(12618..12887)
                     /gene="rpsO"
                     /locus_tag="IXR40_001719"
     CDS             complement(12618..12887)
                     /gene="rpsO"
                     /locus_tag="IXR40_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HAQ4361558.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            13138..13701
                     /locus_tag="IXR40_001720"
     CDS             13138..13701
                     /locus_tag="IXR40_001720"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HAQ4361559.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            complement(13954..14475)
                     /locus_tag="IXR40_001721"
     CDS             complement(13954..14475)
                     /locus_tag="IXR40_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HAQ4361560.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(14478..15320)
                     /locus_tag="IXR40_001722"
     CDS             complement(14478..15320)
                     /locus_tag="IXR40_001722"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HAQ4361561.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELVALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            complement(15313..16038)
                     /locus_tag="IXR40_001723"
     CDS             complement(15313..16038)
                     /locus_tag="IXR40_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HAQ4361562.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEIAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            16214..16510
                     /locus_tag="IXR40_001724"
     CDS             16214..16510
                     /locus_tag="IXR40_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361563.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            17078..18670
                     /locus_tag="IXR40_001725"
     CDS             17078..18670
                     /locus_tag="IXR40_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750719.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAQ4361564.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            18683..19423
                     /locus_tag="IXR40_001726"
     CDS             18683..19423
                     /locus_tag="IXR40_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAQ4361565.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
BASE COUNT         5580 a         4002 c         3702 g         6223 t
ORIGIN      
        1 gggggtgcga caaaagagct tcttcaaaaa aataagtcga aatctcacac aaattcgaga
       61 aataattttc gtaagtttct tcttatttat tgcatctgac cacttctgtt acaacctctc
      121 gttaaacggt gttcaaaagc ttgcatctac gataataagc ccaacccaac gaaaaacgtg
      181 aggagctgtt ttatttggat gctcttatcg cttgatgcaa agacagcttt tttacaacct
      241 ctacttcacg gtgctcaatc agctgacctt cggtattagc tcaaaaaacg gtaaaatata
      301 aacagctatt ttccgtttct tctttttaat acttaggtca agatgctgtt ttcacaacct
      361 cttgttataa ataaaaaaaa cagttggctg gtgactgttc aaaaagcaga atccttgctt
      421 ttcaaacggt cgcagtccgt tcaactgttt cgctgcgcac tatttatggt ttaagaaact
      481 agctactttt gttgtaatca aatcaatagc aacgtggttt tctccgcctt ctggaacaat
      541 gatatccgca tagcgcttcg ttggttcgat aaattgatga tacatcggtt taacaactgt
      601 caaatattgt tcgatcacgg agtccaatgt gcgtccccgt tcttccatat cccgtttgat
      661 acgacgaatg atacgaatgt catcatctgt atctacgtat actttgatat ccatcaagtc
      721 acgcagacgt tcgtcttcta aaatcaggat tccttctaga atgatcactt cttttggttc
      781 ctgaatgatc gttgcctgac ttcttgtatg cgctacatag tcatacacgg gtttttcaat
      841 ggctttatag ttcagtaagt cgcctacatg ctgaatcagc agatcattat caaaggcaaa
      901 tgggtgatcg taatttgtgt tcaatcgttc ttcaaaactc aaatggctct gatccttgta
      961 ataagaatct tgttcaagca tcatgatgga atggtccggg aagttgttga aaatcgcacg
     1021 gctgacactt gtctttccgc ttccggatcc acccgtcaca ccaatgataa ttggcttgct
     1081 ttttgtcatt gactaaaacc tctttcgtat ccgttttttc attctaatct attatagcga
     1141 aaaaacacga aaatgctata tttttctgaa aattaatcct tttcaatttc caataatgaa
     1201 taaagttcct ctaatgaatc gattcgataa gtaggctgga tttcttcgat ttctggtaat
     1261 ttatttctat tgaaccaaat cgtatcgatc cctgccatat ttcctccttt gatatcagaa
     1321 gtcaaagaat caccaatgat cacagtttgc tttttatcaa aattaggaat gtgggaaaag
     1381 acatgatcaa aaaattcttt catcggcttt tgcgctccga cagcttctga gacaaagata
     1441 tccttgaagt aatcaagcat tcctgcatct gttaatcgcc gatgttgcgt gtgcgacaca
     1501 ccgttcgtca caatataaag atcagcatgc ggatggacct ttttcaggat ttctagactt
     1561 cctggaacaa gatcatgacc ttggttcaag tagtggcggt agcgtttttc catttgatca
     1621 ctatctactg ttttcccaaa ttgctggaaa agtaacccaa aacgactgcc tattatttct
     1681 tctcgtgata gtctgccttt ttcaaactcc tgccataaat gatgattcaa agccttatag
     1741 ctggtttcga tttctggtgt caatgtgatt ccttgttctg caaacaaagc acttaaagca
     1801 ttggcttcag ttaattgaaa atctaacaat gtatcatcta catcgaacaa taaagtttta
     1861 tatttcatct ttttgacctc ctatttaaaa taaatactta actttttcat ctctgctaat
     1921 gtcaacgatc gatactcgcc tactcctagc tgttcatcta attccaatgg tcccatgctt
     1981 agccgtttca atgcggtcac tttctttcct tgggctaaga acatcttttt gacttgatgg
     2041 aattttcctt cttggatcgt caataaaacc gtactttggt gcttgtctgc tttgagtatt
     2101 tttaaatcag ccggcttaca ttgataccca tcagcgaata cgattccatt ttcaaatgct
     2161 gttacgtctg ccggtgtcac cctttcgttc acaactactt gataagtctt tgaaaccttt
     2221 ttttctggaa gtagcatttc atatcccaat tgtccattcg aagtgatcag caatagtcct
     2281 gttgtatctc tatctagtct tcccactgga tataatggtt ggaaacgatc ggcacttgca
     2341 atcagatcga ttactgtcgt cttttctgga tctgatacag ctgtaacagc tttttcaggt
     2401 ttattgagaa gataatagga ctcatttgtt tctaagtgtt cacctgctac ttcgatttga
     2461 tgcagtaaac tatctacatt tcgattttgt cgaaattcga ctgtgccatc tatcatcact
     2521 tgcttcaaag caaacagccg cttcatttcc ttgcgtgtcg tttctaattt ttcttctatt
     2581 aatttatcta aacgcatgct gtttcctttc ttattactac taattaatta taccttgaat
     2641 attcttgctt gcaaatacat catcatagtt attccttgac ttaattaaca gttcacgtta
     2701 cggttaaata gtaaagtgaa ttggatttct catacacagc gtaatgacct ggtggagaaa
     2761 agttgaatcc tgactttcta aggggagatg cgcgcatctc tccttttgcg cttttttaag
     2821 cgccctgcct tcgatgatgt gcacgagatt agcctttaga attcacttaa ataaaatctg
     2881 tccgttacca aagcagacag tcacatttta aggaggaatt ttggttatgt cagtatcatt
     2941 agaagtaagt aaaagagaag tacgtccccg ttcattaaga aacaaacttc gtcacgaagg
     3001 gaaagttcca gctgttgttt atgggtataa agtagaaagt acccctatct cattcgatgg
     3061 tttgacacta agcaaattgt tgcgtgaaca tggagcgaac acagtcatca cgatggacat
     3121 cgatggacaa aaagtcaata cattggttca caagatccaa acgaacactt ttaccaatca
     3181 tttcgaacat gcagaatttc tatctgtaaa catgtcggaa gaaacagaag tcgaaacaga
     3241 agtcgttctt gttggcgaat cagtgggtgc taaatctggt ggagtgttag ctcaaaactt
     3301 gtatacagta gtcgtatctg ctacaccaga caaattgcct gaacgaattg aagttgacgt
     3361 gacaaacttg gaattaggtg attctattac agtagccgat cttccaaaaa acgacgatta
     3421 caaattcgtg accgacagtg aagagcaaat cgctgctgta gtcgctcaaa gtgaagaaga
     3481 aagcacaggt gaaggtggcg aaccagaagt gatcggttca acagaagaat aatactgaaa
     3541 caatcaggtg gtgttagaag cggcgggtca gcagctttta acacgccttt tttatttcta
     3601 atcgtttatt ttcatatggg gcttccactt ttgtaaatgg ctttacaaac gaaaaatcct
     3661 aatttaccaa gcttttcctc gcatactttt atcgtacctt tataaaaatt tatactttga
     3721 aaaaaagtat tcaattattg ttgcattttt cctgattctt tattagaatg aaccctcgtt
     3781 gaagtaagta tttctagttt atcctaggat taattataaa aataaaacat tcgttgattc
     3841 gaaggaggtt aaacagatgt ttgaaagttt tgatagcagc cgcaaccgtt acgcttcagt
     3901 tggtgtcgta tcaagtttgc cagatgaatt gattgacagt atatggttta ttattgacct
     3961 agatcttaag ggagtcattc cattagaaaa tatattaacc tttgatttga tcgaaaatcg
     4021 tggaaaagtg acgatgcatt tttctcaagc aggaagcaat gtggaaatgg atattgattt
     4081 gccgtttgcc tattcgaacc aatttcctgc tcaagtatac gcctatgatg acggtacgag
     4141 agaaacgatc cttttaccaa gtgagattag acaatattaa ggtgatagat aaacgtggat
     4201 gtcccttatt ttacagacca ggccaagttg ttgattcttt gactcaattc ttggcttctt
     4261 tttatggagt ttcataaatt atcattgatt tctaattggt attctcagga taaacgctat
     4321 atactactaa ctaaatttta aagatataag gagtttaaaa gatgcgcgat ttaacaaaag
     4381 gaagccccgc taaactgatt ttgatgttca ctgttccttt actgatcgga aatgtttttc
     4441 agcagttcta caatatgatc gatatgatca tcgtgggtca gacgctaggt aaaaatgcgc
     4501 tggcagcggt tggtgcaact ggaagcctga catttttgat cattggcttt gcccaaggtt
     4561 taacagctgg tttagccatt attaccgcac aacgttacgg tgcaaaagat tatcggggtc
     4621 tgaagaaaag ttttgctgct agtgttgtca ttagtcttgt cgtcactgtg attttaactg
     4681 tcctaagtct cctgtttatt cgtccgatgc ttcaattgat gcaaactcct cctgaaatac
     4741 ttgatcaagc acaaacattt atttcaatta ttttattagg gatctttgca tcagtcagtt
     4801 tcaatttgct ttctaatgtc attcgcgcac ttggtgacag ccgcacacca ctattctttc
     4861 tgatcattgc ggtcatcatc aacgtcgtac ttgatttgat ctttattatc tattttggca
     4921 tgggtgtgga aggtgcagct attgctacag taatcgcaca agtttcttcc agcgtactgt
     4981 gtctagtgta tatcaagaaa aaaatgcctt tgttacagtt acgcaaaaaa gatttcaaat
     5041 ttgaaaaaga agagtttgct gtacacctaa atgctgcttt gccaatggcg tttcaatctt
     5101 cgatcatcgc tgttggtgct atcgtgttac aagcagcact aaatagtcta gggacagatg
     5161 tcgtagctgc tcaagccgct gctggtcgta tcgaccaatt tgcaaatcag ccgatgatgt
     5221 catttggtat tgcaatggca actttcactg cacaaaacta tggtgcgaaa gaatatggcc
     5281 gaatcttgca aggggtacgt caaactttac tgatgagtgt cggatttagt ctcttagcag
     5341 gtgctatcgt cattttcttc ggtcatttct ttgttcaatt gtttgttagc ccatcagaaa
     5401 cacgtgtatt tgaattagca caaacctact tcaatatcaa tgggtctctt tactggatct
     5461 tagcagtcct gttcatttta cgctacacac ttcaagggct tggacaaagc aagatcccta
     5521 cgatcgccgg tatgatggaa ttgcttatgc gttcttttgc agctatcgtt cttacaggaa
     5581 tgtggggata cccaggagca gcagcagctt ctcctttagc ttggatcggt tctgttgccg
     5641 tgttgcttta ctcttatatg cgttcgatga aacaattgaa acacatgggt gaagaggaac
     5701 atttcacatt agaacatgca gaagcaagat agccttgatt aaaagaaatc gttgcggcta
     5761 aaaatgaaaa cttttattga aaatatcttc ttcgtttacc gaaaacaggt tttttagata
     5821 acaaaaaggc tgtgacaaaa aatgtcacag ccttttttct tttattctat ttttctttcc
     5881 gtggactcta ctttgaaata atcgatatgt gcatgctggt attctaatac cgtgaaacgg
     5941 aatgatgcaa tctcaatgat tgttcctgct tttatttctt tatatcggct agaagcaaag
     6001 cccgcaagtg tagtaaaatt cgtttcttca aactctggaa tctctacatg aaaataacgc
     6061 tggaaatcat ctaatgttag tttgccggag atgatataag agccatctga ctgttccgct
     6121 atcaatgctt cgtccaaatc tgtctcatct cggatttccc cgacgatttc ttctaaaata
     6181 tcttcaatcg tcactaagcc gcttgtccct ccgtattcat cttttaagat agcaatatgc
     6241 tttccctttt ttcgcatgat cgtcaataat ttttttatag ggatcgtttc agttgttacg
     6301 atcggctctt caatcaactg ttctactgtc agctggtcat ctttataaga ttgcttgatc
     6361 aaatctggca aggtgacata acctaaaaca ttgtcttttg attctaagat aaccggatag
     6421 cgagtatgtc cttgttcaat cgaagctttt atcgcttctt tgacggtttc tgaagcttcg
     6481 aatacttgca tggacgtacg gtctacttgt atatcttttg ccaaggtatc atcaaattca
     6541 aacacgtttt ccaaataatg atattcttct ttggtcaact ctcctttttc ataagaattc
     6601 aatgcgacta atgtcagctc ttcttgagac aatgtctctt ctccttcaga tacgagacgc
     6661 acacctaata gcttccctag ccctgcagct gaatgattca atacccaaat aaaaggaaac
     6721 attactttat aaaaataatg aagtggttta actacgaaca agacgacctt ctccgtattg
     6781 acgatactat agctcttagg aagcagttcg ccaataacca catcgatata cgtaactaaa
     6841 ataaatccca gcgccacaga gattgtactg ctaatagccg aactaaaagg tagtttaccg
     6901 atcactggtt ctagtaaagc cgcgacagat ccttcaccga cccacccgat gatcaaaccg
     6961 gttagcgtaa ttcctaattg actagctgat aaatagttat ctaaatggtg tgtaacatga
     7021 agagctagct tggcgttctt tacattttcc ttttctagtt gttccaatct tgatcgtctg
     7081 attttcacta aagcaaattc acttgctaca aaaaatgaag taattgcaat catcaaaaat
     7141 aaaataatga aattgataac catattctcc cgcctttctc tttttctatt gtaccctttt
     7201 tctacaaaaa gattgaaaat aatgcgtatt catatttagg aataaaaaag gagatgcggc
     7261 atttttcagc cacatctcct tatcacttca aaatcattgc gttacttgtt gctaaacagc
     7321 tttttcatga cctctgataa acggtgttca agtagctgac attcgacatt agttcaggtc
     7381 aaagcgctac tttcacaacc gctctttcaa ccatgttttc cgagtatttc caatgataag
     7441 cggaacagtt tcatgtttta cttcgctgta ctctagccca aaccatgttt ctggcgaggt
     7501 agcgattttt ttgattgcca gttttgcctg catgatttga cgttgccatt ttcctagagt
     7561 tgtcacattg gaaactactt catcaatcag gacaaattgg aaatcgccaa cttctcgccc
     7621 tggtgtcaga gagtatcttt gtggctgttt tggcaaacgg ccttgtttca tcaaatcatg
     7681 gatgacttgg cgaacatata cgttgatttc ctgttggacc ctgaaaccta agaacagatt
     7741 cacttggaca ataaaatcag tgtccatcat atctacttga tattctttcg tatatggctc
     7801 atccgtcact tccacatgaa caaaccaata gactcgtgct cttttaggcc gtttatctaa
     7861 aatcgaatag atgaactgtc ggccaacttt atcttcagcc atatcaggaa ccaagaagac
     7921 cacatttgtc tgatagattg gtaaagaagt atcatcacgt aattctctaa gctgcgggat
     7981 ataatctctc aaagacacat cctcggttga cgattcgcga ataatgttcc cttgttccca
     8041 aataaacatc acgactaaga tgatcaaacc aatcagaacg gctacaaaac cgcctcggaa
     8101 gaatttgaca acacttgaga taaagaaaac gacttctatc gcaccgaaga aaaaggtaac
     8161 taaatatgca agccaacgag aatgcccatt ttggataaga taaaagtaaa gcagtgctgt
     8221 tgtcatcaac atcgtcacag tgatcgatag accgtaagca gcttccatat gatgagacgt
     8281 tcggaatgtg acaaccacta gagaacaggc gatccataaa atcagattga ctgctgggat
     8341 atacatttgc ccgatactgt tcccaggata catgatcttt aaccgaggca gcagtttcaa
     8401 cttgattgct tctgaaacta gcgtaaacga acctgtaatc aatgcttgcg aagcaatgac
     8461 tgcagcgact gttgcaaaag caacgccgat cacgatccaa ctttgaggca tcatttggaa
     8521 gaatggattc aggttcttga tttgctgtgc ttcagggttt tgataaacat tcaacaacca
     8581 cgcagcctgc ccaaaataat tgataaccaa acaaattttg acgtaaggcc agctcagacg
     8641 aatatttcgt ttgccgacat gtccaagatc ggaataaagc gcctctgcac ctgtcgtagc
     8701 caggaaaata tttccaagaa tgaacaagcc taatttgtta tctgcactaa aaagcagctg
     8761 gatagcataa taaggattca gtgcacggat aactgtccag tcttgactga agttcattaa
     8821 tcccattacg cctaaaaaag taaaccaagc gaacatgatt ggtccgaatg cttttccgac
     8881 aatatctgta ccaaagcgtt ggaccatgaa taaaacaaaa ataataacta aagtgataat
     8941 gacgatcacg ttctggttat taccgaaccg gtcaaaaaac tgcggaattc ctcgcaagcc
     9001 ttcaatcgca gtcgttaccg tcacagcagg ggtcaatacc ccatctgcta gtaaggcagc
     9061 tcctccgatc attgcaggaa tgatcaaata tttcccacct tttcggacaa gtgtgtagag
     9121 tgagaaaatt ccaccttcac catggttatc tgcattcaat gcaatcacga catatttgat
     9181 tgttgtcagt agagtcaatg tccaaaaaat caatgagact gatccgataa caaaatcagg
     9241 attgattcct gacaatccgc cattatcttc aacaatcgat ttcataacgt aaagcggact
     9301 tgtcccgatg tctccgtaga cgactcccat cgctacaagc aggccagcca ttgatatctt
     9361 tttggtattg tgcgttgttg ccacgttttt ccctcatttc ttgttatatg gatatccttt
     9421 aggtaagctt gaatgataga tgatattctt atccatgaca cccgctttcc taaattgctt
     9481 ctaattatcc aagtaacaca ctgaagtgtc aacttatttg aataaaatta ttctttcttt
     9541 ggacgttctc tgatacgtct tgccacaaat gaataaagag caaggcaaaa aattgcaccc
     9601 aataatgctg gtatcaaata aaaaccgccg agttccggtc ccagtggtcc tagtaaaaat
     9661 tcgccgagcc aactacctaa aaaaccgata atgatatttc cagatacgcc tcccgggact
     9721 tcctttccta aaattgcgcc agctatcaaa cctaatatac cgccgataaa taacgaccat
     9781 aaaaaattca gcatctcctt tccctccttt atccatattt ctcactttta ttttacgctt
     9841 tattcagaag gactccaaaa atatgcgcca agaaactcca gaaaaaaaga agttgtaaca
     9901 aaagtgttca gcttatttcc gtagaagctg cttctggaac accgtgaatc agaggttgtg
     9961 aaatcagcgg tttgacctga gtattagaga aacaaacgga aaaatagttc ctcatatttt
    10021 gccgtttttt gagctaatat cgagggacag ctgattgaac atcgtttatt ggagaggttg
    10081 taaaaaagct gttctgcatc aagtaataag aacagccaag taaaaacagc tcctaatgtt
    10141 tttaacttgg ctggacttat taccgcagat gcaagctttt gaacaccgtt tattcgaaaa
    10201 aaaaggactg tgacacggct tttgtcacag tccccttttt tcgaataatt attgtccccc
    10261 tgtcaccttc acgatcacaa gtacattatt cctatgaatt aaattatttt tcttcatttt
    10321 tcgttgaacc atcttcgttc aacattgctt ttcttgacag atttacgcgt ccttgtttat
    10381 cgatttcagt tactttcaca aggatctcat cacctagttt aacaacatct tcgactttat
    10441 tgacacgatc gtttgctaat tgggaaatat ggacaagtcc atcttttcct ttgatcaagt
    10501 tgacgaatgc accgaatttt tcgatacgga caactttccc tagataaact tcaccaactt
    10561 tgacttcttt ggtcaaatct tcgatgatct tgatagcttt tttgatcatt tctgcatcag
    10621 ctgaagcaat acttactttt ccatcttgat cgatatcgat tttcacacca gtttcatcga
    10681 tgattccgtt gatcgtatcg ccgcctttac cgataacatc tttgatttta gcaggttcga
    10741 tctggatcat ttcgattttt ggtgcatatt ggcttaattc ttcacgtgga gcagcaatcg
    10801 ttgaagtcaa ttcttctaag atttccatac gtgcttgttt tgcttgagtt aatgcttcag
    10861 ttaggatttg ttctgtgatt ccttgaatct tgatatccat ctgtaaagca gtgataccat
    10921 cttttgtacc ggcaacttta aagtccatat cgccaagatg atcttccagc ccttggatat
    10981 cagttaggat cgtatagttt tcaccatcag aaacaagtcc catcgcaata ccggcgactg
    11041 gcgctttgat tggtacacct gcatccatca atgctaatgt gccagcacag atacttgctt
    11101 gggaagaaga accatttgat tccaatactt ctgctactaa acggatcgta taaggaaatt
    11161 cttcttctga agggattact tgtgctaacg cacgttcacc taatgcgcca tgtccgattt
    11221 cccgacgccc tggagagcct gcacgtcctg tagaaccaac agaaaattga gggaaattgt
    11281 agtggtggat gaatcgtttg ctgacttcca cccctaaacc atcaatgatt tggtgctctc
    11341 ctagaggtgc gagtgtacaa gctgataaag cttgtgtttg tcctcgtgtg aacaaacctg
    11401 atccatgtac acgtggcaat aagctgacct ctgatgacaa tggacggatt tcatccaatt
    11461 tacgcccgtc aggacggatc ttatcgatgg tgatcaattc acgtacgaca tctttttcaa
    11521 gatcttctgt gatttgttta acttctttca acaagtgatc ttcatcttca tgacctgcaa
    11581 atttctcagc ataagcttcg cggatatcga tcttcacctg ctcgatatta tcttcgcgag
    11641 caagtttttc ttcagtcatt actgctgctt tcattgtagc gtaagaagca tcaaagattt
    11701 cttttttcaa tacttcatca acttgcagta aagtcacttc cattttttct ttccctactg
    11761 cttgaacgat ttcttcttgg aaagcaacta actctttgat agcgtcaaaa ccaaacagca
    11821 atgcaccaag catgtcttct tctgaaactt ctttcgcgcc gctttcaacc atattgatgg
    11881 cttgtttcgt tccggcaaca gtcaattcga tatctgtttg ttctgcttgt tctactgttg
    11941 gattcaagac gtactcgcca tttacacgac caacttctac gcctgcgatt gggccgtcaa
    12001 atgggatatc tgagattgat agtgctaaag aagaacctag cattgctgcc atagctggcg
    12061 agcagtctgt ttctacactc atcacgatgt tcgttacttg gacttcatta cggaagcctt
    12121 ctgcaaacat cgggcgaatt ggacggtcga tcaaacgggc agtcaatgtt gcttccgtac
    12181 ttggacggcc ttctcgtttg atgaaacctc cagggatttt ccctgctgca tacatttttt
    12241 cttcataatt gatcgttaat gggaaaaagt ctgtatcttt tgcttcttta gaggccacag
    12301 ctgcacttaa gactactgta tctccataac ggactaaaac ggctccgttt gcttgttttg
    12361 ctagctgacc gacttcgatt tgtaagggac ggccgcccca tgtcgttttg aatacttgtt
    12421 tttctgacat aacttctcct tttccttctc gtgaaagcaa gacgctacta aacaaatgaa
    12481 aactgccgaa agccgtcttt tgagcagctt tcatttggtt agtaggagtc catctagctt
    12541 gatcacggaa ttttacttaa ttgatatacg agtaaaaaaa gtgagattca tgtgaatccc
    12601 actctttttg actaaaatta acgacgcaag cctaaacgtt tgatcaattc gcggtaacgt
    12661 tgaacgtcag ttttacgtaa gtaagctaac aagttacggc ggtgaccaac ttttttcatt
    12721 aggccgcggt atgaatgatg gtcttttttg tgcacgcgtg catgttcatt caagtggttg
    12781 atttcttcag ttaatacagc gatttgtact tctggagaac cagtatcccc ttcatggcga
    12841 gcgtattcgt tgatgatttc attcttgcgt tcttttgaaa ttgccatttc tttcacctct
    12901 ttcgattatt cccctgcgac tgagtaaaac gttggtgatt cgcttaacca agtggcaggt
    12961 catgtgccta gagcacacag ctatacttta cctgaaaccg ggttgaaaat caagtagtta
    13021 atcattaaga aaaggtagtt ttcaaacaat cttactacta cttttccatt tttgtggtaa
    13081 actataatgc gaaaatagac ttgaaacaca gtcttttaag aaaggggtac atattccatg
    13141 attacaatgg atgatatcat tcgtgaagga aatccgacct tacgcgaagt tgcaaaagaa
    13201 gtttctcttc cattaagcga agaagatatc tctttaggaa aagagatgct tgagttctta
    13261 aaaaacagcc aagatccaat caaagctgaa gaactacact tacgaggcgg tgttggctta
    13321 gctgctcctc aattagatat ttctaaaaga atcattgctg ttcacgtacc aagtcctgac
    13381 ccagaggcag atggaccttc tctaagtact gttatgtata atcctaaaat tttgagccat
    13441 tctgttcaag atgcttgttt aggggaaggt gaaggctgtt tatctgttga tcgagaagta
    13501 ccaggatatg ttgttcgcca tgccaaaatc actgtgtctt attatgatat gaatggtgaa
    13561 aaacacaaga ttcgtttgaa gaattatgaa tcgatcgtcg ttcaacatga aatcgaccat
    13621 atcaacggtg tgatgttcta tgaccacatc aacgatcaaa atccatttgc actaaaagaa
    13681 ggcgtattgg tgatcgagta gagaattggc aggttccttc gatactatgc tacaagaaag
    13741 ctttataaaa aaggggagtg ctcaaaagct gcacttccct tttttatgtt tctccactaa
    13801 tcgaaattta gatagacatc tagaaatcgc aattccaaaa aattctgtgt attggatacg
    13861 catcttttct tattttttct tatttcttcc atatgggtgt ttatctcaga gatgatagaa
    13921 tagtttctag gataaaaagt agcagctacg atgttatcct tcgtagagga ttcctgcttc
    13981 agctagtttt tgtttgatgt ttttcagcat atgcttttct gggtagcgga tcgtatgcag
    14041 atggatgccg cctgttaatt cggataacaa agtagcatta cttttttgat aacgtctcat
    14101 aaaggaatcg atatcttgtg gcgttttgat gtgcaaagtt cctgctaact caccgtaaag
    14161 gggatgttcc acaattacat caatgatttc accaccattt tcaacgatta gtctcagttc
    14221 ttcttctgtt tgatcttttc catgctggac agcgatttta ctgatgtgcc cagtattggt
    14281 ttcttctgtt tcgaggatat aacctcttgc tgttgccacg atacttttac ctgcagctcg
    14341 tagtaaagca atatcgccta caatgatctg acggctgact ccaaaagttt tcgcaaactt
    14401 gctagcactc actggttttt ctgtatttgc caaggtttgc atgatttgtt ttcgccgtgt
    14461 ctctccttcg atcacactta ttcctccttc attttgtttt ggtattcgcg cgagtgtttc
    14521 atcaaatcaa catacgtgtc tgttattgtt tccttatatc ccttattttt cagcagacta
    14581 acaactttat ccaatacttg ctgctctctt tttgcatcat aaactgcttg gttttcttct
    14641 tttttcactt gtcctatttt agttaccgta tccattcttt tttctaataa agcaaccaac
    14701 tctcgatcga tcatatcgat cttatgacgt aatgtttcaa gagactcttc tgttagttct
    14761 tcctctactg tcttgatgat acgagcagga tttcctgcaa tcactacatt gtcgggaaaa
    14821 gatttggtca caaccgaacc tgcgccgact actacgttgt cccctagagt gacacccggc
    14881 gtgacgataa ctcctccgcc taaccaaaca ttattaccga ttttaatggg ttttgcgtac
    14941 tccagaccgc tgttacgttt cactggatgt agtggatgcg tcgccgtgta aagctggaca
    15001 ttcggagcga acatgcagtt atcaccgatt tcaatcgtgc tgacatctaa aaatgtacaa
    15061 ttgaaatttg cataaaaatt ctccccaaca aatatattat atccgtaatc aaaattgata
    15121 actggctcca tatagatttt tttccctgta cggccaaaag tctctttcaa caattgggat
    15181 cgcagttccg ctgattctgc ttggttgatg atttggcttt gacttcttgc aaacatacgg
    15241 tcggcaacca gctcaggatc attggcaaaa taaagctcgc ctgcaatcat tttttctttt
    15301 tcggttttga attcagtcat aatctgctcc taattcttgt atttttttga aaacaaccgc
    15361 tccgtcttct tgaataaacg tataaggctc cgctaaataa acaggcgttt gattgattac
    15421 taagattttg gctgacggct ggcgaaactg taccagatca caaaacggat gaacttgaaa
    15481 actcgttcca acaatgacga tcagctctgc ttggctgacg gcataagccg cctgctccat
    15541 gactccatct tgaaaccctt caccatataa cacgatgtct gggcgtattt gtcctccgca
    15601 tgcttgatgt ttgtcgctgt gaagatattc tttccagtct accgtttgtt gacattttcg
    15661 acaatgacat tgatacagac tcccatgaaa attgacgagt tgcgggcttt tagcctttgc
    15721 gtgcaaaccg tcgatgtttt gggaaacaac ccaaacattt ttttctttcg ctagatgtgc
    15781 tatttccaaa tgaatgatat tgggttttgc ttcaggatga taaatctttt tgacaaattg
    15841 atagaattta tccggttcat tcaccattgc ttgatgactc agcaagtatt ccggctgctc
    15901 catcccgtgg tagattcctg acaaagatcg atagtctggc actccagaag gtgtggatac
    15961 ccctgcaccg gtcaaaaatg taatttgctg ataagctaat atctcttttg ctgcttcgtc
    16021 tactgttaat tgtttcatgt tttgtcacct cactttccat tatagcccat actcgaacaa
    16081 atttattgtt gaaaagtcag aaaaatggga ataaaaaagt gttatgggca tttgagcaat
    16141 ttatcacaat gttcactgac aaaagaatga aaacgtgtta caatactgct gtataaaagt
    16201 gaggtgaatc gatatgttac cattctttat ttattggggc gttattctgg cttgtatcgc
    16261 ctggttagcg ttaagcgttt atttctctgt tttttatctt gtacgcaaag aaaatggaaa
    16321 tctttgggct tttgctttat tcaacgtgat tgccgcaatt gttttagcca ttacattagc
    16381 cgtatatcga acatggggct ggggaatcac ccaatactca agtttgattt atctaatatt
    16441 agccatttat ggcgtcgttg ttcttttgca agcgatccta ggacgtgagc caaagaaagc
    16501 ggcagcttaa atgatcgaga tggaactgga cacaggaaat tttctgttct agttcttttt
    16561 ttattgtatt acatacattt ttgtgtataa ttatactatc gtttgcaatg gatagatgat
    16621 tcacattttg attgtttttt cggtaaaagt aaagatttct atatttatca gtattttttc
    16681 aaaaaccagc agttatagat tgacaaagcc tctcgagtat cgtaaacttt ttttgtataa
    16741 ataactgaat acgagatgcc tcaatcaatg aggtagaggt cgcgagaatc attaaccctg
    16801 tggagtgaag caaacatgga gaagcaggaa tagggaggat cgccgaaatg tgcacttttt
    16861 tgcttggagt gtatgttggg acgcaagtta agagcttgcg gactgtctta gcagtgatgc
    16921 taagttgcgc tatgttttgt gagaggttta tcaccttatg gaattttagc ggccttttta
    16981 tatctataaa tcggtcgctt tttatttttt cagataaagc tttaccgcat ttcatctaga
    17041 ccgctcgtgt atcatataat cagaaaggga gaaaaaaatg aaaaaaaata tggtttcagt
    17101 tgccgtacta tttgcttttg tcttctcact attcagtgtg ggatctctgg caaatgcaga
    17161 tgaaaaaaca ccgagcgatg agtttcgcgt aggtatggag gctgggtatg cacccttcaa
    17221 ctggtctcaa caaacagatg agaataatgc cttgccaatt caaggccaaa atagttacgc
    17281 cggcggttat gatgttcaaa tcgctaaaaa agtagcagat ggtttaggga aaaaattagt
    17341 catcgtccaa acgaaatggg atggtctggc tcctgccctt caatcaggca agatcgacgc
    17401 gatcatcgcc ggaatgagcc ctactgctga acgacgaaaa gaaattgatt ttaccgatcc
    17461 ttattacgaa tcacaattag tagtagtagt tcaaaaagat agcaaatatg caaaagcaaa
    17521 aagtttagca gatctttctg gagcaaagat cactgctcag ttaaatacat tccactatac
    17581 tgtgatcgat cagataccag atgtgcagaa acaacaagca atggataatt tctcagcaat
    17641 gagaacagct ttagcttctg gaatgatcga tggttatgtc agcgaacgtc cggaaggtgt
    17701 aacggcaact agtgtgaaca aagacttgga aatgcttgaa ttcagcggtg cagatggctt
    17761 ccagacaaac ccggaagatg ttcagatttc tgttggtatg cgtaaaggcg acccggatat
    17821 ccaaaaagta aaccagattc tttctggcat ctctaacgat gaacgaacca aaattatgga
    17881 ccaagcagtc aaagatcagc ctgctgcaac tgatagtgaa gaaaaacctg gcatcatttc
    17941 tgatttcact acgatttgga aacaatacgg caatatgttc ttacgaggtg ctggacttac
    18001 cttgttcatc gcattgatcg ggacagttgt cggtactaca cttggattac tgattggtgt
    18061 cttccgttcg gtacctgaat caggaaatgc actgactcgc ttcttccaaa aaatcggaaa
    18121 tgcacttctt tctatctatg tcgaagtatt ccgcggaaca ccgatgatgg tacaagcaat
    18181 ggtcatcttc tacggtctgg cactcgcttt tggcatttca ttgaaccgaa cgattgccgc
    18241 tttgtttatt gtctctctca atactggagc ttacatgaca gagatcgttc gtggggggat
    18301 ttttgcagta gatgaagggc agttcgaagc tgcgcaagcc attggtatga cccatggcca
    18361 aacgatgaga aaagttgtta ttccacaagt tttacggaat atcttgccag caacaggaaa
    18421 tgagtttgtt atcaatatca aagatacagc agttttaagt gtaatcggcg tagctgattt
    18481 gttcttccaa ggaaactctg cttccggtgc gaatttccaa ttcttccaaa catttacgat
    18541 cgtcgggatc atctacttag tcatgacctt tacgatcacc agaatcctgc gggcggtaga
    18601 aaagaaaatc gatggtcctt cagcttatac caagcttgaa gaaatcgaca attcaaattt
    18661 gcaggaataa ggaggaagaa tcatgaatga aaaaattatt gaaatcaaac atctaagaaa
    18721 aagcttcggt gaaaatgaag tattgaaaga tatcagcgta acagtcaata aaggtgaagt
    18781 tgtgacgatc atcggttctt ccggttctgg taaatctact ttcttgcgct gtatcaattt
    18841 actggaaaaa ccaacaggcg gcgagatcat ttataatgga gaaaatgtat tagctcctaa
    18901 atataattta cctaaatatc gaacgaatct aggtatggtt ttccaatcct tcaacctgtt
    18961 caacaatatg aatgtcttgg aaaactgtat gtctggtcaa acaactgtcc tgaaacgaga
    19021 taaagaaact gccaaaaaag tagcaatcga aaatctggaa aaagttggta tggatcgtta
    19081 tatcgaagcc aaaccagcac aattatctgg tggacagaaa cagcgtgtcg caattgctcg
    19141 ggcattatca atgaatccag atgtattgct attcgacgaa cctacttcgg cgttagaccc
    19201 tgaaatggtt ggcgaagtgc ttaatacgat caaagactta gcacatactg gcttgacaat
    19261 gcttatcgtg acgcatgaga tggaatttgc aaaagatgta tctgaccgtg tcatttttat
    19321 ggataaaggt gtgattgcag aagaaggtac accagaagat atctttgtcc atccgaaaga
    19381 agaacgtaca aaagaattcc tttcacgtat tttaaatgct taggatcaat agctgattgg
    19441 gacaaagagc tgcggtgttt accgcagttc ttttttatga attactcata aaaggtaaat
    19501 ttctgaa
//
LOCUS       DACGEU010000051        18974 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.051, whole genome shotgun sequence.
ACCESSION   DACGEU010000051 DACGEU010000000
VERSION     DACGEU010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18974)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18974)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18974
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.051"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            <1..614
                     /locus_tag="IXR40_001727"
     CDS             <1..614
                     /locus_tag="IXR40_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HAQ4361566.1"
                     /translation="VFAPLEGEDLASFLVGAAIMMIGMTLFLFGADYSMMEVGDLVGK
                     YMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQQVYDISDGEIGRVLLIGIVSVGTG
                     VFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFTSSEFMPIAFDSGGVTTGPVTVPFI
                     LALAGGMTSMIKQKKNENDSFGMVGIASLGPILAVMILGVIFQ"
     gene            611..1384
                     /locus_tag="IXR40_001728"
     CDS             611..1384
                     /locus_tag="IXR40_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HAQ4361567.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            1381..1779
                     /locus_tag="IXR40_001729"
     CDS             1381..1779
                     /locus_tag="IXR40_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HAQ4361568.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            1964..2635
                     /locus_tag="IXR40_001730"
     CDS             1964..2635
                     /locus_tag="IXR40_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361569.1"
                     /translation="MNFLVVLKDTLIERFTFLYVQLQENKTLLHFSPEFHLEGLTLGE
                     IYQAEGLSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQQKILKSFLKVISKKRNLIKTTQLLKKYPGLLHTSI
                     QFPQLITMIHRFIRMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVA
                     MEKAN"
     gene            2694..3134
                     /locus_tag="IXR40_001731"
     CDS             2694..3134
                     /locus_tag="IXR40_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361570.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            3146..3814
                     /locus_tag="IXR40_001732"
     CDS             3146..3814
                     /locus_tag="IXR40_001732"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HAQ4361571.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            3878..4501
                     /locus_tag="IXR40_001733"
     CDS             3878..4501
                     /locus_tag="IXR40_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HAQ4361572.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            4557..4943
                     /locus_tag="IXR40_001734"
     CDS             4557..4943
                     /locus_tag="IXR40_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HAQ4361573.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            5156..6547
                     /locus_tag="IXR40_001735"
     CDS             5156..6547
                     /locus_tag="IXR40_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HAQ4361574.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
     gene            7158..7526
                     /locus_tag="IXR40_001736"
     CDS             7158..7526
                     /locus_tag="IXR40_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HAQ4361575.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            7706..8647
                     /locus_tag="IXR40_001737"
     CDS             7706..8647
                     /locus_tag="IXR40_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HAQ4361576.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            8716..9447
                     /locus_tag="IXR40_001738"
     CDS             8716..9447
                     /locus_tag="IXR40_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HAQ4361577.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            9591..11771
                     /locus_tag="IXR40_001739"
     CDS             9591..11771
                     /locus_tag="IXR40_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HAQ4361578.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            11791..12273
                     /locus_tag="IXR40_001740"
     CDS             11791..12273
                     /locus_tag="IXR40_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HAQ4361579.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            12289..13050
                     /locus_tag="IXR40_001741"
     CDS             12289..13050
                     /locus_tag="IXR40_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HAQ4361580.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            13181..14515
                     /locus_tag="IXR40_001742"
     CDS             13181..14515
                     /locus_tag="IXR40_001742"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HAQ4361581.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            14822..15307
                     /locus_tag="IXR40_001743"
     CDS             14822..15307
                     /locus_tag="IXR40_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydratase"
                     /protein_id="HAQ4361582.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            15300..15983
                     /locus_tag="IXR40_001744"
     CDS             15300..15983
                     /locus_tag="IXR40_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HAQ4361583.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGITLAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            16109..18754
                     /gene="polA"
                     /locus_tag="IXR40_001745"
     CDS             16109..18754
                     /gene="polA"
                     /locus_tag="IXR40_001745"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HAQ4361584.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELAEKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            18799..>18974
                     /locus_tag="IXR40_001746"
     CDS             18799..>18974
                     /locus_tag="IXR40_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HAQ4361585.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRG"
BASE COUNT         6247 a         3231 c         4174 g         5322 t
ORIGIN      
        1 ttgtttttgc accgttagaa ggagaagacc tcgcttcatt tctggttggt gcggcaatca
       61 tgatgatcgg aatgacgctc tttttgtttg gagcagatta ttctatgatg gaagtcggag
      121 atctagtagg gaaatatatg atcaaaaaga aaagtttgac cgttttggtc agtttgggat
      181 ttgctatcgg gatcgtgatc acgattgctg aaccttccgt gcaagttttg ggacaacaag
      241 tatatgatat atctgacgga gagattggca gagtgttgct gattgggatc gtcagcgtcg
      301 gcactggagt atttctagcc tttgcgctgc ttcgggtcgt attcaagcta tcctattatc
      361 aattgatggc tataggctac ataggcgttt tgatcgcctc atttttcacc agttccgaat
      421 ttatgccgat tgcttttgat tcggggggag tgactactgg tccagtaact gttccattta
      481 tcttggccct tgccggaggg atgactagta tgatcaaaca aaagaaaaat gaaaatgaca
      541 gttttggaat ggtcggtatt gcttcgttag ggccgattct tgccgtgatg attttggggg
      601 tgatcttcca atgagtttct ggcagcaagt gatagatgga atcgaaatcg ttaccatgga
      661 agtcattttg gcagtggcac ctatcgtaat cctatttgtt ttaatgaata tcattagttt
      721 tcgtatgcgc aaaaagcgtt tctttgacat tatgaaaggt ttcttgataa cgactattgg
      781 gttgatcctt ttcctgcacg gagtcaatat ggcttatgta ccggtaggac agcatttagg
      841 cagtgctatt gcgggattgc cttacaatta tatactggtt ccccttggct ttttaatggg
      901 gttcttagta gggtttgctg agccggcgat tcatgtaatg atcaaacagg ttgaagaatt
      961 gagcgagggg agaatccgat cgaaaatcat gctgatggta atttcaattg ggatcggcgc
     1021 agcagtagga ttgtctatgt ggcgtttgct cgtcggattc tctctttatt atttcttgat
     1081 cccaggatac gggctagcat ttattttagg acgaaaagtg gacaagatct ttttagcaat
     1141 ggcttttgat aacggtggag tagcaacggg cccgatgtgt tcgacattta ttttatcaat
     1201 gagcgtggca atcgctgcac aaattgaagg aagagatccg atcattgacg ggtttggtgt
     1261 ggttgcaatg attgcattga caccaatatt atccacttta gtactaggat atatttataa
     1321 acgaaaagat gaaaaagaca gaatcgaaaa agaaagattg caaaaattgg gggaaagcaa
     1381 atgaaagatc ttgtagcatt gaatcttcac atgattgtga cgatcgttga cggaggaatg
     1441 ggcgaagatg ttatcgactt ttcaaaagaa gcaggtgcag caggcggaac gatcttacat
     1501 ggaagaggtt ctggtgtaca tgattcaggg aaatttttag gtttggacat ttcgccagaa
     1561 aaagatattg tgttgacatt agtacccgat agtttgacga ataaagtaat ggatgcgatt
     1621 ggtcaaggca tcaacatcga tattccaggt aatggtattt gttttagtat tgatgtagac
     1681 aaagtcattg gtatcactaa gattcatcaa tatcgagaaa ttatcggaat gcaagaactt
     1741 ttagatgaaa ataacgatag agaaaagtct gaatcataga caagcgtttg aagaggaaat
     1801 aaacacaaac aagaaggcgg atgagcgtta tttccgcttt tttgtttgta tttttctcgt
     1861 gaatacttat gaaatagtaa atttttatga aattctactc taagcatcag actttctttt
     1921 caaaatatgc tattttaaaa atgatgaaaa aagggggaga aaaatgaatt ttttagttgt
     1981 tttaaaagat actctgattg agcgatttac atttctatat gttcaattgc aggaaaataa
     2041 aacattgctg catttttcac cagagttcca tctagagggg ctaacattag gagaaatcta
     2101 tcaagcagaa gggctgtcgg ctgttttgca cttttttaag gtagaattgg aattaccagt
     2161 aaaagattat atcgagcttt ctcttgaatc ttgggatcga gcagtggttg aactgtttcc
     2221 agaaggttta atgatcgata caaacgatgg gaagatccat ctgactgcag cagaactgca
     2281 aaaacaaatg cgttatcaaa tagatgacga aaattctttt tctattttta gacgtcagca
     2341 aaagattcta aaaagctttt taaaagtgat cagtaaaaaa cggaatctga tcaaaacgac
     2401 acagctgttg aaaaaatatc caggtctgct tcacacgtct attcaatttc ctcaattgat
     2461 tacgatgatc catcgtttta tacgtatgca acagctacca tctaagaagc tgtttcttcc
     2521 attgacggac acatttcgag tagtcaacag agaagataaa aagaaagtga ttgtgattga
     2581 ctttaccaga aatcggaatg tccttcacca agttgcaatg gaaaaggcca attaaggctt
     2641 tttctttttg gatttttttg tcataataaa tattagatga tggaggagat aatatgatgc
     2701 aaacatggtt agaaaggcta atacgatttc agcagaacta tcacaaactt atgcagggaa
     2761 gatatgcgaa atttgatcag ttgaatcgcg gtctattgat cgctgcgctt gtctttagtt
     2821 tgctaagtcg ttggttgccc tatagaatcg gacaattgtt gttcatcgtc tttttcggat
     2881 ggatgatatt tcgtttccta tcaaaaaaaa tctaccccag actaaatgag aatcaacgtt
     2941 atttgaaata tcttgataga gtcaaagaaa aatatcatca gataaaaaac aaaaagcaag
     3001 tcaaaatgga tcgaaaaagt tatacttttt ttgagtgccc gaattgtcat caaaagcagc
     3061 gtgcacctaa aggaaaagga cgaatacgtg tgacatgcaa aacatgtggt ataaaattcg
     3121 aaacgaatgt ttaagggaga aaagaatgaa attagtatta ttacgtcatg gcgaaagcga
     3181 agcaaatttt gaaaattact ggacaggatg gctagatgtc gccttaacag aaaaaggaaa
     3241 agaacaagca gcagttgccg gtcaaaaaat gcttgaagcc ggacttcaat tcgatgccgt
     3301 ttatacctct gttttgaaac gtgcgattct taccggacaa gtcgcactag aagaaatggg
     3361 tcagttatgg cttcctataa taaaaacatg gcgtctaaat gaacggcatt atggggatct
     3421 tgtgggtaaa aacaaagata agatgaaaga aatatacgga aaagatcaag taaaaacatg
     3481 gcgcagagga tatacggaag ttccgccgtt aaccgcagaa aatagatttg accgcagata
     3541 tgatcacttg gatccgcatt tgatcccata cggagaaagt ctggaaatga cagtgaatcg
     3601 gatcattccc ttatggcaag atcatctagc accaaaacta aaagatcggc aagatttact
     3661 agttgtgggt catggtaata gcatccgagc actgacaaaa tatttagaag atgttcctga
     3721 agatcaaatg gatacgatcg atatcccaaa tgcacaacca atccagtata cattagcaga
     3781 tgatttgaca attctggaca aaaaaatact ttaaagaaca cctttatcta aaagtgagag
     3841 atagaaaaaa gaagcaaagg aatggaacaa aaggaacatg aaaaattata tatgggactt
     3901 tgatggtaca ttgtttgata cgtatcccgc aatggtagat ggtgcatggc aagcactaaa
     3961 agattttggt atcagtatgg acaaaaaaga aatctacttc aaaatgaaaa agtattctac
     4021 tagttatttg atcaatgaat caaacttgaa tgccagagag tttaatgaat tatttcaccg
     4081 atatgaaaaa gaaagtacgg aagtttcccg tccatttcca gaaacgaaac aagtactgga
     4141 aatgctaaaa gacaacggcg gtcgtcattt catcctgacc caccgtttga cagaatcaac
     4201 atggggcctg ttaaaagaac atcgattggc acatctgatt gaggaagtag tagggatcga
     4261 tcaggacttt cctcgtaaac ctgatccagc atctttaaat tatttgatcg atacttttca
     4321 tttagaaaga acagacacga tgatgatcgg cgatcgtcgt ttagatatcg aagcagggaa
     4381 aaatgcagga gtcgctactt gtctttacga catcgatcat tttctgggtg agatcccggc
     4441 agattatgtg gtaggaaatc tgaatgaaat ccttaccttg cagagcatca ttaaaaagta
     4501 gtatcccctt tcaaaggaga tatgttataa ttttcataaa ggagtgataa aattatatgg
     4561 aaatcagaag acaaaaagaa gttgtagaag catttcatta tgatatgaga ttgccgaacc
     4621 aagaagtaga aacagatttg aaagtaggct tctcgccttt aaaagaaacg atcgaaaact
     4681 atccgaaaga acatagcatc gtaggagcac gcttagagtt ccgtttagtg tttgatacat
     4741 atgttttatc tggaagtgtg agtcagatca atcatatcct caatcggaaa attgaaggtc
     4801 aaaatgatgt cacacaagaa gaagtggacg agctagtagc accgttattc gatatcgtac
     4861 gccgaatgtc ttatgaggtg acagagatcg ccttagatca gcctggggta aaattgaatt
     4921 ttcaatcaga aaaacaagaa tagacagtaa aaacatacct gcgatagatt aaagctatca
     4981 caggtatgtt tttttattac taattgtaag caaaaagaat gtcatttcga taaaaatcgt
     5041 ctaaaatata aaagtcactg aaaaaaattt tttcaggagg atggttgaag aatcattctc
     5101 gggaaccttt acttccttcg atggacttgt cattaataat atgaggagga gaaaaatgac
     5161 aacactcatc acagttttag tggttctagt ttttgcggca ttattatatg tgttctatcg
     5221 tatgcaaaag cgccatacaa aattttcaac acgcgtcttt acagcattag gagttggtat
     5281 cgtctttggc ggtctgcttc aattgatctt tggtgtagac gacaaagtcg ttactcaatc
     5341 aatggaatgg atcgggattg taggtcaagg atatgtatca ttcttgcaaa tgctagttat
     5401 gcctttagtg tttatttcga tcattggtgc attcacaaaa atgaaagttt ctgaaaagct
     5461 agggaaaatt agtgcgactg tattgacttc tttacttgga acaacagcta ttgcagcatt
     5521 gatcggaatt ggttcaacaa tgctgttcgg actccaagga gctaaattca cacaaggagc
     5581 tgcagaaaca gcacgaatct ctgaactggc aacacgtcag gaaacagttg aaaacttatc
     5641 gattccacag cagattttat cctttatccc taaaaacgtt tttgctgatt tagcaggtag
     5701 tcgtgcaaca agtacgattg gagtcgttat tttcgcggca tttgtcggaa tcgcttatct
     5761 aggcgtgaaa agaaaagcgc caaaagaagc agcattcttt tcagatttag tcgacagtct
     5821 gtataaaatc attatgcgga tcgtgacgct tgttttgcgt ttgacacctt atggagtatt
     5881 tgctttgatg acaaacgttt tggcaacaag tgattttgca gctatcgtca atttaggtaa
     5941 atttgtcgtt gcttcttacg tagcattgct tgctgttttg attgtccact cactgatttt
     6001 gattggtgca aaagtcaatc caatcaacta tttcaaaaaa gcctttccgg tattgagctt
     6061 tgcgtttact tcacgttcaa gtgctggagc tttgccattg aatatcgaga ctcagacaaa
     6121 agctttagga gtagatgatg caacagctaa tttctcagca agttttggtt tgtctattgg
     6181 acaaaacggc tgtgctggcg tttatccagc tatgttggca acgatcgtcg caccagcagc
     6241 tggagtgaat gtctttagtt tggaatttat tttgatgctt gtggcaattg taacaatcag
     6301 ttcttttggt gtagctggag tcggtggggg cgcaacattt gcttcactga tcgttttagg
     6361 ggcaatgaac ttgccagtag caatcgttgg gttagttatc tctgttgaac cattaatcga
     6421 tatggcacgt acagcagtaa acgtcagcgg tagcatggta gctggtatcg tgacaagtgc
     6481 acgcatcaaa gatttagatc gcgatgtcat caatgatgat tctaaagtga tcgatgtgaa
     6541 tgcatagtca aaaagaggtt gtgatagaag tggtcagctt taagaaataa gaagaagttt
     6601 cctaaaaata gtttctcaaa tttttgtgaa atttcggctt atttccgaga agctacttct
     6661 gaaacaccgt gaataagagg ttgtgaaaaa gctgccctgc atcaagtaat aagaacagcc
     6721 aaacaaaaat agttcctcat attttacgtt tggttgagct tattaccgca gatgcaagct
     6781 tttgaacacc gtttaagaaa gaggtcgtga gcctgccgtt tcactctgag tcacaaagag
     6841 caatttcaaa aaatagcttc tcatgtttgt tgaatattgt gtcttgtgac cgaggagttg
     6901 tcaggagaac accgtttacc agaggttgtg acttgttttt agtcacgacc tcttttttta
     6961 tttattccat ataaatacac attatttatt ccgaaaagtg aaagcgcaaa taacaaaaac
     7021 aaccaactta tttattatta aagaaaagcg tatttaagta ggacgattct gttgagagct
     7081 ttcgtagatt ttcccatttt cctatggtaa actgacaaag ttgagaatgt tagaacagat
     7141 cgtttaggag gaaacagatg tttacgaatg aaataaaaat catgctttat gtggacgatg
     7201 tagaaaaaaa tgcaacgttt tggagagcag ttggctttgc ggaaaaagat cgtcaagaaa
     7261 tggatgggac gcttataatt gaagtaggag ttgaggacag tcaaacctca tttctgttat
     7321 atgatcgagc atttgttgag tcccattcac ctggcacagc tactagtgcc ccatctttga
     7381 tgttttacag taaagatatc tttggactat ataaaaaaat gcagacgcaa tcagtcacat
     7441 taggtgatat ggtacagctt ggagaagaat atgtctttaa ctttgctgat cccgatggca
     7501 actactttgc ggttacaggt aaataataga aataaagact ttgtttttct gtgcgaaaca
     7561 ggaaagcgaa gtctttttaa ttcaaataat aatattatgt aaacaaaaaa ctttccatgc
     7621 gtaattatac acaagcaaat aaatcgtcaa atgcgaacgc cttctttata ctgtttagga
     7681 acgaaaagaa ggaaggaaga aatacatgga ttatcaagta ctgctttatt acaattatac
     7741 aaaaatcgaa gaaccagagg aatttgccaa aaatcattta gccttttgca aatctttgga
     7801 tcttaaaggt cgtattctag tagctgaaga aggaataaat ggtactgtgt ctggaaccgt
     7861 tgaaaacacg actgcctata tgaaagcaat gaaagctgat cctcgatttg ctgatacgat
     7921 gttcaagatc gatccaagcg aaggacatgc ctttaagaag atgtttgtaa gataccgtcc
     7981 agagcttgta agtttaaagc tagaagagga cattgatcca aaccaagtga caggtgccta
     8041 tctttcaccg caagaattta aagaagctat tttagatgaa cagacagtgg tgattgatgc
     8101 acggaatgat tatgaatatg acttgggaca ttttcgaggg gctgtacgcc cagatatacg
     8161 cagttttcga gagcttccag actggatccg cgagcacaaa gaagaattta tggaaaaacg
     8221 ggtagtgacc tactgtactg gtggcattcg ttgcgagaag ttttctggtt ggcttgtccg
     8281 tgaaggattc aaagatgtcg gacagctgca tggcggtatt gctacttatg gtaaggatcc
     8341 tgaagtccaa ggagaattat gggacggcaa gatgtatgtg tttgatgaac ggatcgctgt
     8401 cgatatcaac caagtagata aacaaatcgt cggtcgcgac tggtttgacg gaacaccatg
     8461 tgaacgatat atcaattgta gcaatcctga gtgcaatcgt cagattcttg cttccattga
     8521 aaatgaagaa aaacatttag gagcatgtag catagagtgt gcgaaacatc cgcgcaatcg
     8581 ctatgttcaa gaccatggaa tctctccaga agaagcagaa ctgcggttta cagctttaat
     8641 taaatagaaa acaatagttt tgattgtcga ccatttccaa tatgcgctat actagcgttg
     8701 aggatggtga tccacatgaa atcattgatt tatgctattg gggatgtcca tggcaaacat
     8761 gagctttttg aaaaacttat tcactattat gatccaaaga tccatcagct tgttttatta
     8821 ggggatctca atgatcgagg tcctcgtaca aaagaatgtt ttttattagg aaagcaatta
     8881 gtcgaagaaa caggagccat ttacctccgg ggaaaccatg aagaatattt tttgcaattt
     8941 ctgcaatcac cggaggactg gtatgcgcct tatatgagaa atggtggaaa agaaacgttt
     9001 gaaagcctga ttcacccagg ggcatcggag gaatactccc caactgaaat ctcgatgatg
     9061 atccaatcga gatattcaga actgattaaa tttttagtcc agcgcccctt gtattatgaa
     9121 tgggaaaatt atctttttgt ccatgccggt gtggatttga caaagaaaga ctggcgtaag
     9181 acaagtctaa gagactttat ttggataagg gaaccatttc atgaagggaa aaacaataca
     9241 ggtaagacaa ttgtatttgg acatacgatt acaccaatgc tccatggaga tatgcagaca
     9301 acagacctct ggattcagga tcataaaatc ggaatggacg gtggggctgt attcggaggg
     9361 tcattgcatg gggttgtttt tgacaaggaa ggtattcttc aagatattga atatcagaac
     9421 aacgaaggac cttggcatgg aatctgacta atggaaagaa tgaaggagct gtgactttgt
     9481 tgcggctctt tttattttta tagagaatat tgtttctttc agtagtttaa cccaggataa
     9541 aaagtatgat agaataaaga agcaattttt agcagaaaag aggcatttta atgacggaaa
     9601 atttgaacca gacgatcatt cagcttgtac aaaaagaact ttcagactat cgtcctaagc
     9661 agttgactac tgtacttaat ttgttaaatg aaggaaacac tgttcctttt atcgcgcgtt
     9721 accgaaaaga aatgactgga agtcttgatg aagtccagat tcgtgaaatc gaagagcggt
     9781 atgcctatct tgaaaactta gaaaaacgta aaactgaagt gattcggcta atcgatgaac
     9841 aagggaaact gactcccgag ttagaagcag aaatcaccca agccgtgaaa atgcaacaag
     9901 tggaagattt gtatcgtcca tacaaacaaa aacgacggac aaaagcaacg attgctaaag
     9961 aaaaaggact tgaaccactc gcgaagtggc tgatgcagct tacagatgga gaggtgcaat
    10021 ctgaagcaga aaaatatatt gacaaagaaa aagaagtctc ttctgccgaa gaagcgttgc
    10081 acggtgctca tgagattatt gctgaacaag tcagcgataa tgcaaaattt cggacttgga
    10141 ttcggtctta tacgtataac aaaggtatgt atgtcagcaa tgtcaaggat gagcaagcag
    10201 atgaaaaagg cgtatatgaa atgtattatg actttgcaga acccgtccat aaaatggttt
    10261 ctcatcgaat attagctact aatcgtggag aaaaagaaga tattctgaaa gtattctttc
    10321 aagtagatga agcagcaatt ttagcttact tggatcgcca aatagtcaaa aatcctgcct
    10381 ctccttcttc ttcattcgtc agagaagcct atcaggatag ttataaacgc tttattcagc
    10441 cagcaatcga gcgagaactg cgcaatgaat tgactgaaaa ggcagatgag caagcaatcg
    10501 ctattttcgg cgaaaacctc cgtaatcttt tgttgcaacc gccactaaaa ggtaaagttg
    10561 tcctgggatt tgatccggct tatcgtactg gatgtaaact agcagtcgta gatgcgacag
    10621 ggaaagtttt agcaatcgaa gttatttatc ctcataaacc tgcagcgcaa gcaaaaagag
    10681 aagctgctgg accagctttt atccaattaa ttaataaata tcaagtagat atggtagcta
    10741 tcggaaatgg tacagccagt cgggaatctg aactttttgt ggctgagcag ttgaaatccg
    10801 ccgaccataa aacctattac gctatcgtca acgaagcagg cgcttctgtt tactccgcta
    10861 gcgaaattgc acgaaaagaa tttccgcatc tacaagttga agaaagaagt gctgtttcta
    10921 ttgcccgtcg cctgcaagat cctttagctg aattagtcaa aatcgatcct aaagctgtcg
    10981 gagtaggcca gtaccaacat gacgtttctc aaaaacgttt ggctgaacaa ttggattttg
    11041 ttgtggaaac agcggttaac caagtaggtg tggatgtgaa tacagcaagc ccgcagctct
    11101 tgcagcatat atcaggattg aataaaacaa ctgcccaaaa cattgtcatt tatcgtgaag
    11161 aaaacggaga attcaccgca cgaactcaat tgaaaaaagt gccacgctta ggaccaaaag
    11221 catatgaaca agcaatcgga ttcttgcgag tccctggtgg gaaaaacatt ttggacaaca
    11281 caggtatcca tcccgaaagt tattctattg caaaagaaat attaacttca gtccaacttt
    11341 cagaaaaaga gcttggtaca gaagaagcag tagaaaaatt gacacgatta tccgtagaga
    11401 aactggctga aagcctatca gtcggagaag aaacgttagc cgatatttta gctgggctga
    11461 cacaacctgg acgagatatg cgtgatgaga tgccagcgcc cttattacgt acagatgtat
    11521 tgagtatgga agacttgaaa ccagggatgg aattgactgg aacggtccgt aatgtcattg
    11581 acttcggcgc atttgttgat atcggtgtga agcaagacgg acttgtccat atatcgaaac
    11641 tcagcaaaaa attcgtcaag catcctacag atgtcgtgtc agtaggagat atcgtaacag
    11701 tttggataga acaagtcgat acgaaaaaag gcagaatcag tttgacgatg ctttcccctt
    11761 atgaagagta acaatgagga gtaacaaaaa ttgacacaag aagaactgca gcagttagta
    11821 gaagagatat cattaaaaag cttccagctt cctttcaagc accaagcaat gttcaatcca
    11881 cgcttacgta caactggcgg gcgctatcat ttaaacgatc atcatttaga ttttaatgcg
    11941 aagctatttg aagagtcaga cgaagagacg attgcaggaa tcatcaaaca tgaactttgc
    12001 cattatcatc ttcatctagc tggaagaggg tatcagcata aagatatgga tttcaagtat
    12061 cttttgaaaa aaacaggagg gttgcgctat gcaccagcct tgacgaagaa acagataaag
    12121 atggagtatt atcgatgcca agattgttct gccacgatct gccgcaagag aagaatcgat
    12181 gtacgcaaat atcgttgtgg aagatgtcat ggagaaatca aatggattga gacaaaaaga
    12241 gaagacttta atgaagcaca aaaaatcaga tgaaaggata gaaggccttt ggaaaaaagt
    12301 gagcagagga atctaaaaga ctggaatcag ctattaaatt ttttagccgc acctgaagag
    12361 ggaaattttg aggaactgac ggcacctaca cttattttag ctggaaactg tcttcctatc
    12421 ttagctgata aagcagcaca aatgtattta aatggccaag tagatcaatt gtttttggtc
    12481 ggaggggtgg ggcatgcgac tagaatcctt tatgagaatt ttgaaaagca aggatttcat
    12541 tttgaagatg gcatgagtga aagtgaaatc tgtcgtcagt atctaaaaga agtctatgat
    12601 ttgcccgata aggcttttct gatagaatcg aagtctacaa attctggaga gaacgccact
    12661 ttttcactgg agattcttca ttccttagga gctgtaccag aaaaaatctt attgatgaat
    12721 gatccgacac tgcaacgcag gactcgagca acttttgaga aagtatggca aaatgaacaa
    12781 actattttcg cgaatgctgt gccatttgtg ccggaaatcc ttcacttttc tgaagagatc
    12841 atctttacag caaaagaact gaatcatcaa tggcctaagg aatatttcca tgcgctagta
    12901 ttaggagaaa tggaacgtct ccatgacgat gagaacggct atggtccgaa aggaaaagat
    12961 tttattcctc acattgatat atcagaggaa gtttggtctt cttacaccag aattaaagag
    13021 tcaataaaaa cggatttttc tcgtacttga ccattttagc aagcgaatcc tcctttccaa
    13081 ataaatttgg ttgaaatttt caatcgttta taagataatg aggagcgtgt tgaatgtaat
    13141 agctaaaaga atggacgcta gataagagaa gaggattcaa atggaaaatc aaaataaatt
    13201 gtatcatttt gttggtatca aaggttcagg aatgagctcc ttggctcttg ttttacatga
    13261 acaaggtcta aatgtccaag gatcagacat tgaaaaatat ttctttacac aaagagattt
    13321 agaaaaagca aatatcacga ttctgccatt taacgcagat aatgtaaaac cagggatgac
    13381 gatcattgca ggaaatgcat ttcctgattc acatgaagaa atccagcgag caaaagaatt
    13441 aggtttggaa gtgattcgct atcacgactt tattggtcat tttatccaaa attatacgag
    13501 tatcgctgta acaggctctc acggaaaaac aagtacgact ggactgctct ctcatgtatt
    13561 gagtggtgtc cgtccaacaa gttatctaat tggagatgga acaggacatg gtgatccgca
    13621 agcggaattc ttttcatttg aggcctgtga atatcgccgt catttccttg cctattcacc
    13681 agactatgca atcatgacca atatcgattt tgatcatccg gattattata caagtatcga
    13741 cgatgtattt acagctttcc aaacaatggc tggacaagtg aaaaaagcta tttttgcgta
    13801 tggtgacgat gcttatttac gcaaattaaa agcaaatgtg ccgatttatt attatggtgt
    13861 cacagaaaac gatgatatcc aagcacgaaa catcgaacgc acaacttctg gttctgcttt
    13921 tgatgtctat catggggatg aatttgttgg gcacttcact gtaccagcat tcggtaaaca
    13981 caatatctta aatgctttag gtgttattgc agtagcttat ttcgaaaaac tggatctgaa
    14041 agaagttgca gaagaaatgc tgactttccc aggagtaaaa cgtcgattca gtgaaaagat
    14101 cgtagcagac atgaccgtag tcgatgatta tgcgcatcac cctgcagaga tcaaagcaac
    14161 gattgatggc gcacgccaaa aatatccaga taaagaaata attgcagttt tccaacccca
    14221 tacgtttacg cgtacgattg cattgatgga tgaatttgca gaagcacttg atttagctga
    14281 taaagtttac ttatgcgata tttttggttc ggctcgggaa gaacaaggaa acgttaagat
    14341 tgaagacctt ggagcgaaaa tcaaaaaagg tggagaagtc atcaaagaaa ataatgtatc
    14401 tccattgtta gattatcatg atgcagtagt aatcttcatg ggtgctggag atgttcaaaa
    14461 atttgaacaa gcgtatgaaa aacttttaag cagcacgacg aaaaatgtac tgtaatacaa
    14521 ttactgcagt gtccttataa aaatagaaag agggggagtg gcaaaaatct tgccaagccc
    14581 ccttttttgc aacttatgat aaacggtgtt caaaagcttg catctgcggt aataagccca
    14641 atcaaatcaa aaacatgaga agctgttttt tcttggctgt tcttattatt tgatgcagga
    14701 cagctttttc acgacctctg taaactatag gaatctgtta aatcaaggga gcagaacttg
    14761 ccttttacgc tacttttggt acaataatgt atgattaaaa ataaactgga gggtttctat
    14821 cttgaacata ggtaagccga gaaaactagg aaaaacaata aatgaaatcg aggaaggcga
    14881 ctcgttatcc ttaacagaat ctattgaaga taaccagctt ttgctgtatt tgggattgac
    14941 gaatgatgca aatcctttgt atatccaaca tgactttgca caaaaaacag aatatcaaca
    15001 gccaatcgtt ccatcagtga tgctgatggg gatcatcaca agtgcaattt caaagcatct
    15061 tcctggacca ggatcacatg ttgtcaattt ttctgtcaat tttattgaac cggttttcca
    15121 ttatgaaaca ctgacttttc agtttgaggt cataaaagta gataagatga aggatgtggt
    15181 gacgatttct gtagaagcgg agaatacgaa cgaagatcgt gtgttggatg ctgtcgttat
    15241 ggtccaaccg ccacaagttc ctgaattgga aatagcaatc gaaagtgaag gtgaattgaa
    15301 tgaataatcc aagtacatca atgtcaggta tcaatcgttt ttatgcaaaa gtttatggat
    15361 ttttaggtat gggacttgcc cttagtgcag tcacttctta cttggctctt tgggtatttc
    15421 ctttgcaatt agcaactttt atcaataatt ttccactagg ctttgtgggt ctgtggatcg
    15481 ttgaactgat tttagtaatg gttctaggcg taaaagcaca aaagaatccg agcttagcaa
    15541 tcggtggatt tattgcctac tctcttttga atggcataac attagcggtt actcttgcat
    15601 actacgatat tggaacagta acgcaagctt tcttgacagc tactttgatg ttcatgggga
    15661 tgtctgttgt cggagtaaca acaaaaagag atcttagcgg ggttggaaga gcaggacagg
    15721 cagctttaat cggagtgatc attgcactag tcttgaacat cttcattttg agaagtagcg
    15781 tagttgagct gttcatctcc ctactgttag tcgtcatctt tgcagggatt acagcttatg
    15841 ataaccaaag catccgtaat atctatgtcc agacaaacgg aacagcacat agtggaattg
    15901 ctgtattcat ggcattgaag ctgtatttgg actttatcaa cttgttcttg gcgtttctga
    15961 gaatctttgg acggaacaac taaaaaagaa aaaaattcat cagttggggc tataccgaat
    16021 tatttggtat ggtcccgctt tttcttttcg cattccgcag gattctttgt tagaatgaat
    16081 aagaacttta cagtaaggag ttaagaagat gacaaaaaat aaattattac tcgttgatgg
    16141 gaacagtgtg gcttttcgcg cattctttgc gcttcacaat tctcttgaac gtttcaaaaa
    16201 tagaaacggt cttcatacaa atgcaatcta tgcattcaat acgatgtttg aaaatgttat
    16261 gcaaaaagag caaccgactc atgttctggt tgcgttcgat gcaggaaaaa cgacttttcg
    16321 gacagaaatg tatgcggagt acaaaggtgg aagatccaaa acacctggcg aattcaaaga
    16381 acaaatgcca tatatacgtg atttgttgac aggactaggg gtacagtatt acgaattgcc
    16441 caattatgaa gcagatgata ttatcggtac tttggcagaa aaagtagaca aagatcaatt
    16501 tgatgtcgtc gtgctttcag gtgatcggga tttgactcaa ttagctagta aagaagtaaa
    16561 agtggatatc actgtaaaag gtgtcagcga tatcgaaagc tatacaccag aacatgtagc
    16621 ggaaaaatat gatgggttga cgccaaaaca gattattgac atgaagggac tagccggaga
    16681 tgcctctgac aatatccccg gtgtgactaa aatcggtgaa aaaacagcta tcaagctatt
    16741 gaaacaatat ggctcagtcg aaggaattta tgaacatatc gatgaaatga agcaaagcaa
    16801 aatgaaagaa aatctgataa atgacaaaga gcaggctttc ttatcgaaaa aattggcgac
    16861 catcaatact tcagcgcctg tggatgtctc tatcgactca ttgaagtatg aagggaaaaa
    16921 tctcgataaa ctcgttccgt tttataaaga aatggatttc aatcagttcc tttctaaatt
    16981 gaatatcgta gaagaagaag taaaaatgga tgatattttg tttgaagtcg ttcatgaatt
    17041 caaagaggaa atgtttacta cggatatggc gttgtacgtg gaaatgatgg gcgacaatta
    17101 tcatacagag gaaatcgtcg gagtagcgtg ggggacagaa aagaaaattt atgtcacgaa
    17161 cgatctatct gtattcgaaa accgagcgtt ccattcttgg atcactgatc cgactcggct
    17221 gaaaaaagta tatgatgcga aacgaactta tgttgcttta aaccgctata ctggaaaaac
    17281 gaaaggaatc gattttgatg tcttgctagg tgcatacctt ctcgatacga atgaaaaaag
    17341 cacagatatc gaaggaatag ctgctcatta cggatacaac gatatccaat cagatgaagc
    17401 tgtatacggc aaaggggcga aaaaaggttt accagaagaa gaggaactct tttttgctca
    17461 tttagcgcga aaagtagctg caatcaatgc gttgacacca aaattgagcc aagaactggc
    17521 agaaaaaaac caagaagatc ttttccggaa aatggaactg ccattgtcta tcattttggc
    17581 agagatggaa ataagcggga tcaaagtaga tgcgactcgc ttacaagaaa tgaagggcga
    17641 gttctctgct cgcttaagag agatcgaaca aaaaatctac gaagaagccg gcgaagaatt
    17701 caatttgaat tcaccaaagc aattaggagt gatcttattt gaaaaaatgg gattacccgt
    17761 tatcaaaaaa acaaaaactg gatattccac agccgtagat gtactggaac agcttcgtga
    17821 acaagcacca atcgtagagg atatcctcac ctatcgtcaa attgcaaaaa ttcaatctac
    17881 ctatgtcgag ggactgctga aagtgatcca atcagatgga aaagtgcata cccgttatgt
    17941 ccagacattg acccaaacag gacgattaag ctctgttgat cctaatttgc agaacatccc
    18001 gattcgatta gatgaaggga gaaagatacg tcaggcattt gttcctagag aaaaagactg
    18061 gctgatttat tcttctgact attcacaaat cgagttacgc gtacttgcgc atatctcaaa
    18121 tgatgaacat ttgaaagctg ccttcctaga aggtcaagat atccatgcca gcacagcgat
    18181 gcgtgtattt ggaatcgaaa aggcagagga tgtcacacca aatatgcgta ggcaggcaaa
    18241 agcagtgaat tttggtatcg tgtatggcat ctctgattac ggactttcac aaaatctagg
    18301 aatcagccga aaagcagcac agcaatacat cgatacgtac tttgaaaaat acccaggtgt
    18361 caaagaatat atggaaagaa tcgtacgcga agcaaaagac caaggctacg tcgaaacgct
    18421 gtatcaccgc cgtcgatatc tgccagacat caattcaaga aattacaata tccgttcttt
    18481 tgcggaacga acagctatca atacaccaat ccaaggaagt gctgctgata ttttgaaaat
    18541 cgcgatgatc gaattggata aacgattaaa agaaacaggt cttcaagcta cgatgctgtt
    18601 acaagttcat gatgaacttg tcttcgaggt accggaaaaa gaacttgaat cattagataa
    18661 attggtgaag gaagttatgg aacaagctgt ttctcttcat gtaccactga tcactgacag
    18721 cagttgggga aaaacgtggt acgaagcaaa ataaacattg tttaagacag agcaatataa
    18781 tgaaggtgaa aagaaaaaat gccagaatta ccagaagtag aaaccgttcg taaaggattg
    18841 gaacggttag tagtaggaaa aacgattcaa aaagttcagg tcttgtggcc caagatcatc
    18901 gagcaaccag agacacccat ctttgaggct tctcttgttg gcgaaaccat ccaatccatt
    18961 ggacgtagag ggaa
//
LOCUS       DACGEU010000052        18822 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.052, whole genome shotgun sequence.
ACCESSION   DACGEU010000052 DACGEU010000000
VERSION     DACGEU010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18822)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18822)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18822
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.052"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(99..1229)
                     /locus_tag="IXR40_001747"
     CDS             complement(99..1229)
                     /locus_tag="IXR40_001747"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HAQ4361586.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     gene            complement(1788..2861)
                     /locus_tag="IXR40_001748"
     CDS             complement(1788..2861)
                     /locus_tag="IXR40_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAQ4361587.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRK"
     gene            complement(2858..3685)
                     /locus_tag="IXR40_001749"
     CDS             complement(2858..3685)
                     /locus_tag="IXR40_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4361588.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            complement(3686..4492)
                     /locus_tag="IXR40_001750"
     CDS             complement(3686..4492)
                     /locus_tag="IXR40_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4361589.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            complement(4504..5589)
                     /locus_tag="IXR40_001751"
     CDS             complement(4504..5589)
                     /locus_tag="IXR40_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4361590.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            complement(5606..6148)
                     /locus_tag="IXR40_001752"
     CDS             complement(5606..6148)
                     /locus_tag="IXR40_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4361591.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            6406..7395
                     /locus_tag="IXR40_001753"
     CDS             6406..7395
                     /locus_tag="IXR40_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HAQ4361592.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIITFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            7392..8129
                     /locus_tag="IXR40_001754"
     CDS             7392..8129
                     /locus_tag="IXR40_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HAQ4361593.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            8126..8677
                     /gene="coaC"
                     /locus_tag="IXR40_001755"
     CDS             8126..8677
                     /gene="coaC"
                     /locus_tag="IXR40_001755"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HAQ4361594.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            8693..9325
                     /locus_tag="IXR40_001756"
     CDS             8693..9325
                     /locus_tag="IXR40_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAQ4361595.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            9410..10057
                     /locus_tag="IXR40_001757"
     CDS             9410..10057
                     /locus_tag="IXR40_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAQ4361596.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            10062..11045
                     /locus_tag="IXR40_001758"
     CDS             10062..11045
                     /locus_tag="IXR40_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HAQ4361597.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
     gene            complement(11448..12962)
                     /locus_tag="IXR40_001759"
     CDS             complement(11448..12962)
                     /locus_tag="IXR40_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HAQ4361598.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            13100..13906
                     /locus_tag="IXR40_001760"
     CDS             13100..13906
                     /locus_tag="IXR40_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361599.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            complement(14081..14650)
                     /locus_tag="IXR40_001761"
     CDS             complement(14081..14650)
                     /locus_tag="IXR40_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4361600.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(14733..16793)
                     /locus_tag="IXR40_001762"
     CDS             complement(14733..16793)
                     /locus_tag="IXR40_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361601.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            complement(17070..18548)
                     /locus_tag="IXR40_001763"
     CDS             complement(17070..18548)
                     /locus_tag="IXR40_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAQ4361602.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
BASE COUNT         5586 a         3768 c         3271 g         6197 t
ORIGIN      
        1 aaataaataa tataaaaggt aaataaaaaa gagtggattt ctccactcca tgaaaagccg
       61 actttttggg acgctttttt ttgccaagcc tcacattttt atagccaaac ttcttttgcg
      121 acttgctgca ataattggat tttcttccat tgttcttctt ctgttaaatg gtttccttct
      181 tctgttgaag caaacccaca ttgaggactg atacttagat tttccaatgg tacaaattgt
      241 tgtgcttctt ttattcgttc ttttattttc tccgtatctt ccaaatctgg aaacttagaa
      301 gtaactaatc ctaaaacaac tttactttct ttgttactcc aatgtcttaa aggagtaaaa
      361 tctcctgctc ggtcagaatc gtattccaaa aagaaaccat cataatttgt tgaaaacaac
      421 tcttctgcaa tgggttcata tccaccggaa aacagccaag aagaagcgtg attcccgcgg
      481 cagatatgtg ttgtgatcgt caaatcttct ggtttgtctt ccagtgcgtt attgataatc
      541 tctgtacaaa tatgggccat ttctttcgga tcaattcctt tttgaagaag tgcttctctt
      601 ttagtttgat cagctagaaa cgcccaattt gtatcatcga attgcaggta acggcaacct
      661 ttttcataaa aagcatgaat cgctgctttg taagtagagg acaagtcctc ataaaaatca
      721 gatagatcag gataaatctc cttgattttt gaagaaccat cattagatag gatctcttgt
      781 cgtaaaatca tcgtgggact agggatcgtt gcttttgcaa caaaagtatc atctgtttcc
      841 actacttctt tcagaaaagc aaaatctttt aaaaatgggt gatttggatt gaaagataat
      901 ttatctacta cccgaatatt ataagctggt gctgcttttc cgtggaatgt ttgattatat
      961 ccagtttctg gaacatagcc ttcgatacca tttagttctt ctaaaaaatc aagatgccaa
     1021 aatccacgcc gaaattcacc atctgtaatt cctttgatgc cgactgcttt ttggtcttcc
     1081 actaattttt ttatttcctg gtcttcgatt gcacgaagtt cttcttttga aagtaagcct
     1141 tcttgaactt tttttcttgc ttctttgatc gattgcgggc gtaagaaact tccgacatga
     1201 tctactgtaa atggtctatt tttgctcatt tcactcactc ttttctttgt tttttgtaaa
     1261 aaaaaatcct tttactagca aatactagta aaaggacgat tatactcgtg gtaccacctt
     1321 ttttcagaaa aaacattctt tctctcagcc tgacaataaa atcagtggtc ttggtaacga
     1381 aagactgttc gtttttgcct acctttcgac aaaaaatcct ctaaggccat tttcgacagt
     1441 caacttctag ctttttacac caaccaaagc ctctcttgaa ccattttctg tctactttcc
     1501 ttctcatcgg atactattag aataaaatta gaatagcatg tttgaaagaa aagtcaatag
     1561 ggaataagaa caaacaaaaa ctaatttgtt attcttagta atttgtttgt ggaatacaat
     1621 aaagcttttc taatatgata attgttcagt cgtcctttca tcttagatca cttccttaaa
     1681 atgatcatac ccgtttcaac cacataaaaa aggacttaat tttgaaaaat ttcccatcaa
     1741 aactaagtcc tttttattat agttatgcaa atttgcttat tttctcgcta tttccgatac
     1801 atcttgaatt ctaagaatag gtcattatag atgcctaggt atttcgatcc tagatctttg
     1861 tagacttcaa gatgggagat cgtgtcatca gatggataga attgttcgtc cgacgaaatg
     1921 tcttttggca ataacgcttt tgcttcttca tttggtgtag aataaccaat atactctgca
     1981 ttttgtgccg cattttccgg ttctagcata aagttgatga aatcataggc accttcttta
     2041 tttttcacgg tttttggcat aacgatatta tcaaaccaaa gattggatcc ttctggtggg
     2101 atcacataat gtaaatgttc attttcccac atcatatcgg cagcttcgcc agaaaatgtc
     2161 actgccacgg aggcttcttc attgatcata tacattttga tctcatctgc cacgattgct
     2221 ttgacatttg gtgttaaatg attcaattta tttgctgctt ctgtcagctg tgccatattc
     2281 ttactattca aagaatagcc taaactattc aaagaaagcc ccataacttc tcgtgcaccg
     2341 tcaatcagca tcaaactgtc ttttaattcc ggcttccaca aatcatccca atgcttaatt
     2401 tgatttgcat caaagaattt atcgttatat acgatcccta aagttcccca aaaatatgga
     2461 atcgaatact gattatctgg atcaaaatcc aagtctaaaa atcgtggatc aatattattt
     2521 aatcctttga tcttcgaatg atctaatgga agtactagtt tttctttgat cattttttgg
     2581 atcatatatt cacttggtat agcgatgtcg tagtttgtcc caccttgctg gatttttgtg
     2641 aacatcgctt cattagaatc aaatgtttca taattcactt tgtatccata ttctttttca
     2701 aatttcgtga tcaaactagg atcgatataa tctccccagt tatagatggt aagtaccttt
     2761 gctccactca tgccacttgt tttttcaagt tgacgaacac caagcagcag caccgcaata
     2821 atgatgagaa tacctaaaaa cagagattgt aattttttca tcgcagccgt gccaccccct
     2881 cgcgtactct tctgtttttc ttcagccgtt ttggacggtt ttctttacta ataaagtagt
     2941 atccaatgac caatatcatg gagaacaaga aaactaacgc acttagcgca ttgatttcta
     3001 aactgattcc ttgtcttgca cgagaataga tctctactga gagcgtcgta aagccatttc
     3061 ctgtgacgaa aaatgtaacc gcaaaatcat caagagaata ggtaaatgcc ataaaatatc
     3121 cagctatgat tcctggagaa agataaggca aaatgatatt tttgactact tggaaattat
     3181 tagcaccaag gtctctagcc gcatcgacca ttgaatcgtt catttcctgc aattttggca
     3241 agaccatcaa gacgacgatt ggaatgctga aagcaatatg ggaaagcaat acactctgaa
     3301 aacctaatcc gaatcctagt agtgtaaaga aaatcaagaa actagcaccg ataataacat
     3361 caggagagac taataagatg ttattcatgc tcaacaacgc tgtccgtgca cgtcgttttt
     3421 tcgtgtaata gattcccata gccccaaatg tcccgatgat cgtggcgatc aatgcagata
     3481 agaaagccag catgaacgta ttcaatacga taatgatcaa acgtgtatct tcaaaaacag
     3541 cttcataatt ttcccaagta aatcctgtaa agctgttcat cgttcctcct tcattgaagg
     3601 aataaaaaat cagatagaag atcggtgcat ataagaataa aaagacgatc cctaaataaa
     3661 gatacgacca tttaaatttt ttcatttatg agcgacctcc ttttttcttc tcgcctgtca
     3721 ggagcatcac gatgaacata gcaatgatta aaatcacacc gattgtagaa cccatccccc
     3781 agttttgtgt aaccaagaaa tgctgttcga tagccgttcc taaagtgatc acccgatttc
     3841 cgccaatcag acgagtcagc atgaataaag aaagagaagg aataaatact gcttggacac
     3901 cacttttcac accatttaat gataacggaa aaatcactcg tcggaaggtc tcaaagctat
     3961 tcgcgcctaa atctctacta gcactgatca aagaaggatt catctcttcc aatgcattga
     4021 aaattggcat aatcataaat ggaatctcga tatacgttgc cacgaacaga aaactgaagt
     4081 ctgtgaataa tatctgtttc ggcccgatcc cgataaaatc aaagaaatga ttcacgctgc
     4141 cgtgcacact gaaaatccca ataaatgcgt aagctttaag cagcagattc acccatgtag
     4201 gcaaaataat cagcatcagc cataattgct tgtgcttcag ttttgttaaa aaataagcag
     4261 tcgggtaact gatgatcagc gtgaaaaacg tgatcaaaaa tgcataccat acagaattga
     4321 tcgtcataga aagcgatgtc cccgacgtaa aataagatag ataattattc agcgtgaatt
     4381 gcccattcat atcaaaaaaa gattgataaa tgatcattaa tacaggcgcg atcacgaata
     4441 aaccgagcca caaaatataa gggacggaat agatcctgcg cattgttttc attcttgtcc
     4501 cccctattct tcgtagctgt caagacgtgc atcgaattct tcttcagact cgttgaaacg
     4561 catgacatgg atatcttctg gctcaaaggc caatcctact ttgcttcctt ctttagcttt
     4621 tttcgttgaa tggaccatcc attcattttg ctgttcatca taacagatga tttcataatg
     4681 gacaccacga aacagctgag tatcgaccgt tacgactagt tttcctttat ctggtgtcgt
     4741 gatcgtcaaa tcctctgggc gtaaaacaac ttcaactggt tcatttagac gcatcccgcc
     4801 atcgacacat tcaaattgct taccaacaaa ctcaactaga ttatcttcga tcattacacc
     4861 gtccacgata ttgctctccc caacaaaatc agcaacgaaa tgattgattg gctcatcata
     4921 aatatctacg ggtgtaccac tttggacgat tttcccttta ttcatgacaa aaatctcatc
     4981 actcattgcc aacgcttctt cttggtcatg agtaacaaaa ataaacgtga ttcctaatcg
     5041 ttgttgcaga tcccgcagtt catactgcat atctgtacgt agtttcaaat caagcgccga
     5101 taacggttca tctaatagca atactttcgg ttcatttaca attgctcgtg caatcgctac
     5161 acgctgtctt tgaccaccag acatttcact aatctcccgt ttttcgtatc caggaagctg
     5221 gaccatacgc aaagcatctt ttaccttctt ttcgatatct gatttggaca ttttcttgat
     5281 cttcaatcca aaagcaacgt tatcaaaaac attcatatga ggaaaaagtg cataatcttg
     5341 gaagactgta tttacttgtc gcttattagc tggcaaatca ttcaaccgtt tcccttcaaa
     5401 atagatgtcc ccttctgtag cttcggtgaa tccagctata atacgtagga tcgttgtttt
     5461 accacagccg gaaggaccaa gcagtgtata aaattttcct tgttcgatct caaaacttac
     5521 tttttttaat actgtttcat catcatagcg tttcactact tgatcaaatg aaatgattgg
     5581 tttccccacg tttttacccc ctatattaca aatatgattg cgttgcaaca atcaatactt
     5641 ttgttcgttt tttgagatga ttccttaatt gatgttgttt tgtcgcttga taatagatcg
     5701 actgtcctgc ttttgccaca tagaccgtct ctcctaagct taactctaat tccccttcta
     5761 atacaaaaat aaacgtttca gataatgaag gttcaaacgt cttatattct cctgcacctt
     5821 caaaagtcag caagacaggc tccatttctt tttcattcga atcagccacg agccattcca
     5881 attcataccc gttttcttca tcgaaataaa ccgtatgatc ttcttttgaa taaaccactt
     5941 gcagattcgc tgcttcttga tgaaaaaatt cttctggagt cacacctaag acttcaagaa
     6001 tagaaaagaa tgtttccatt gatggtgaac ttaaatctcg ttccaactgg gaaatatacc
     6061 cttttgacaa atctgtgcgt tcgcctagtt cttcttgtgt caaattcttt tggatgcgca
     6121 aatttcttaa cttctcacca atttccataa tttcctccga atcgaagttt tctaatagta
     6181 aacttcctgt ttactaccac tcgtattagt atacgaaatt tattgaaaaa ggcaaccctt
     6241 tgtaaaattt tttttgctga atatttcttt atcttttgga ataaattcta gttgtttgat
     6301 tctttatttt tcacctaatt tttgtctaaa tttacggaag aacaagaata aaagagtagg
     6361 ctttatggta tgataaaaga aaattttaaa aggagtgtct cacgaatgaa cgcttttcga
     6421 tcttttcagg taataaagga acctgttttc catacagcaa tcagtgatct gccatttact
     6481 gagttggctg aaaatgaagt cttggtaaaa attgcctatt ctgatgtcaa ttataaagat
     6541 gcattggcaa tgagcgagtc tggtcaggtg atacgaacat atccgatgac tccagggatt
     6601 gatttatccg gaactgtcgt ccaaagtaac aatccacgtt tttcaaaaga agatcttgta
     6661 cttgctactg gttttgggct tggcgtcacc catccaggcg gttatagcca atatcaaaaa
     6721 gtaccaggag actggttagt tcctctacca aaaaatatga cgctgcgtca agcgatgatc
     6781 cttggtacag cagggtttac tgctatgttg tgtgtgaacg ctttaatccg tcaaggtatg
     6841 acctccgata aaaaagttgt cgttactggt gcttctggcg gtgtaggcag tacagcgata
     6901 gccctgttac ataaactagg attccagtca atcattacct tttccagaaa agaagagtct
     6961 gtcacatggc taaaaagtct aggtgctttg caagtcgtac gacctgatga atttctgcca
     7021 gagacaacaa aagctttagg aaaacagcaa atcgactatg tcatcgacac agtaggtggc
     7081 gagcagctaa gcagtcttct tccattgatc tcttataacg gtgcagtagc tttatgtggc
     7141 aatgctgggg gaatcaaact aaacgcgact gtcttgcctt ttattctgcg aaacatccag
     7201 ttgattggaa ttgattctgt caatgtacca atagatcaac gtctttcttt atggcaacag
     7261 atggcggatt tgcagattgc agatgaactg gtcgtccaag agattactct ggatcaattg
     7321 cctgaaacag catctaaact acttgctgga acacaccaag gaagaacact agtaaatgta
     7381 ggtgaccata aatgaagatt ctaatcacag ctggaggaac gactgaaaaa atcgatcaag
     7441 tacgtgctat tacaaatcat tcgacaggac gattagggca agcattagct gattatttag
     7501 ctgccaatcc ggataccaca atcgattacg tgactacgaa acaagcactg aaaccgaaaa
     7561 gacactccaa tataacgatt tatacgatcg aatctgcact ggacttattt ttacaattag
     7621 aagaactaac gaaaaaagaa cactacgatg cgattatcca cagtatggca gtcagtgatt
     7681 ttactcctgc ttttagtttt tcagaagaac agctggcaaa aaacctaccc acttcttcaa
     7741 cgcaagaaga actggacaat tggtttgcgg aaaatgaaca gacagatacc actgtttcaa
     7801 agatctcttc taacaccgag catcttgtgc tcgttttgaa gaaaacacca aaaatcattt
     7861 cttatctacg tgaatggcag ccaaaagcaa aaatcattgg tttcaaacta ttagtagatg
     7921 taccaaagga atctcttctg gcagtcgcaa aaaatagtct gataaataac aaaactgatt
     7981 ttattttcgc aaatgatttg acggaaatcc atggcgagac acaccacggc tatctcttat
     8041 ctaaagatgg aacagtggaa gaagctcaaa gtaaatctga gattgctgca ttgattactg
     8101 agaaaattag actggaggaa tcaaaatgaa aaagatctta ctaggcgtta ctggaagtat
     8161 ttctgcttac aaaagcgctg atcttacaag tcaattcgtc aaattaggtg cccaggtaga
     8221 tgtgattatg tctaaaagca gcacacattt tatcacgcca ttaaccttgc aatctctgtc
     8281 gaagcgcgca gtccatacag acgtcatgca agaatcaaat ccgcaggtaa tcaatcatat
     8341 cgaactagca aaacaagctg acttgtttct catcgcgcct gctacagcaa acattatcgg
     8401 caagctagca aacggcattg cagacgatct tctttcaaca gtcgcaatgg cgcttccagt
     8461 gggaacacca aaattgattg cccctgccat gaacacgaat atgtatcaaa acccgatcac
     8521 tcagcgtaat ctggaaacat tgagatctgt cggctatcag gaaattgaac caagagaatc
     8581 tcttttagct tgtggagatt ttggaaaagg tgccttagct gatattcaga cgatcatcga
     8641 acaggtcatg ctgactctta atgaaagaaa tgcttagaaa aaaggagtac ttatgaaaaa
     8701 tacaaaaaac tttacattaa ctgcgatgtt tttagctatt ttgattttat tagctgttac
     8761 gcctttaggt tttatcccta tcggtccaat caatgcaaca accatgcata ttcctgtaat
     8821 cattgcttcg atcgttttag gaccaagact aggtgctttt cttggcggta catttggact
     8881 gatcagcatg atccgtagca cagttatcca aacacctttg tcttttgtct tttctccgtt
     8941 tatcccagtc atcggaacag aacatggaag ctggaaagcc ttgctgatcg cgtttattcc
     9001 tcgcatcttg attggggtgg ttccttattt cgtttataaa ggtctgcgca aactaatgaa
     9061 acaaaaagca gattccgttt ctttattctt agctggactt tccggttcat tgaccaatac
     9121 gattttagtg atgaatatga tctacttttt attccagcaa gattatgcca aagtcatcgg
     9181 aacaaattta aatgctgttt attcagctat tctagcggtt atttttacaa gtggtatacc
     9241 tgaaggaatc gtcgcaggtc ttgcgactgc agcagtatgc aatgtcttgt taagatactt
     9301 caagcaccct tctcttacta actgatagtc atcgtagccg atctctgatt tttttctctt
     9361 ttggtgttac tattgaatgg aaagatttga cgtcgaaagg atgatccaaa tgaaaatttt
     9421 tgttgtaggt gcaaacggac aaattggccg acacctgata aaagatttag ctccaagttc
     9481 ccatgaaatt tttgcagggg tgagagatgt tgcttcccaa acattagtaa aaaaagagaa
     9541 tgtttcgtat gtctcttttg atttaacttg gtccgtggaa aaaatgaccg aagcattcaa
     9601 aggcatcgat gtattgattt ttgctgccgg ctctcaagga aagaatcttc tgcaagtaga
     9661 cttggatggc gcaatcaaaa cagtgatcgc agctgaaaat gcgcatgtct ctcgctatct
     9721 gatggtcagt gctgtttatg cagatgaacc agcaaaatgg cctgagtcca tgacagatta
     9781 ttatattact aaacattatg cagatgaatg gctgaaacga actaacttag attttgtcat
     9841 tcttcaacca gtcacattga ctaacgatga agaagttact tccattcaat taactaagcc
     9901 taatgagaag gcatcaaaaa cgatcactcg ctctacagtt gctgctgtac ttgccgctct
     9961 agtggaagaa acggatattt ctcgtacgac tctagtactt tctgaaggta gcaaagagtt
    10021 gaatacagca ttccaagaat gggcaaagga ggaatagatc catgcgtgcc atttcaatca
    10081 agcatcctgg ttctgtagat gtattagaac aaattgaagt gcctgttcct aaaccaaaac
    10141 aaggcgaatt actgatcaaa gtccatacag cagctgtcaa tcgaacagat attatgaaaa
    10201 gagaatcagt ctctttgaaa cctccctacc ctattttggg agtcgaagta gctggagagg
    10261 tagttgagaa taaaagtgat atctccactt ttactcctgg gacaaaagta tacggattag
    10321 tcaatctagg tggttatgcc gaatatgctg tgatgcctgc cgatcgtgca atccttctcc
    10381 ctgatacgct agactatgtt tctgctgctg gaatctcaga agtttttttg actgcttatc
    10441 aaacacttta ctggcttgga aaattacaag aaggcgaaac tgtcttgatc catgcaggag
    10501 caagtggtgt gggaacagca gcgatccaat tagctagaca gctttctcac gcgaaaatca
    10561 tcgttactgc aggatcagaa gaaaaactcg ccttttgtaa agaacttggt gcagatgaat
    10621 tgatcaacta taaaaaacaa gactttcaag aagaggtacg aaaaatcact gaaggtcggg
    10681 gagtcgatgt tattttggat ttcatcggcg cttcttactg ggaaaagaat ttagcttcta
    10741 tagccgttga tggacgttgg gtcttgattg gtatgctagg tgggaccatc gtgcctgaga
    10801 tagaccttgg tgtattgatt gggaaacgtg tccaactgct tggtacatta ttgacaccta
    10861 gaagtgatca gtataaagca gagctcgcac aaacttttat gcaaaaagct gggccttttc
    10921 tagaaaatgg caagattcgg ccaatcattg accgtacatt ccaattcagc gcagtcaaac
    10981 aagcgcatga atatatggaa gcaaacaaaa acatcggaaa aatcattttg aagataactg
    11041 aataaaatca tgctgatcaa aaaagaggct gggacagaag cgtttaactc caagaaataa
    11101 gaagaaattc acgaaaattg cttttcaaat ttttgtgaat ttcagcttat ttccgaagga
    11161 atttcttctg cttccgccgt ttatacgtgt ttagagcgtg agacaaaagt gttctttact
    11221 tttgtcccac gctctttttc cgaataaacg gtgttcaaaa gcttgcatct gcggtaataa
    11281 gtccaaccaa gttaaaaaca taagaagctg tttttacttg gctgttctta ttacttgatg
    11341 cagggcagct ttttcacaac ctcttcacta aacagtgttc aatcagctga ccctcggtat
    11401 tagctcaaaa cgctgatttc acaacctctt tttatttacg ttctatttca ttcattttcc
    11461 gaagcaaatc gagctgcttg tatgcccgct tgtcgcccaa aaataatgat ctccgcaact
    11521 gaatttccac cgatccggtt gtttccatgt aagccacctg tgacttcacc agcagcatat
    11581 aaccccctaa ttggctggtt ttctttatct aatacttcag tgttcgtatt gattttcaca
    11641 ccgcccatcg tgtaatggat tcctggtgcg attttgatcg cataataatt cggagacgat
    11701 aagtcatgtt ccatggctgt ggcacggttg aattgagcat cttttttctc cgcaacatcc
    11761 gtattccatc catcaactgt ttttgctagt gtttcttttg gtaaatcgat tttttctgct
    11821 aattcttcca ttgtctttcc agttgtgaca tatccttttt ggtcataaaa ttcaatagct
    11881 gtggcacgat cacgcacgcc ttggtcaaaa atcaaataag ctgatttttc aggcaatgct
    11941 gtaattgctg cagatacttt atcccttgta tccatttcat tgacaaatct tttcccctct
    12001 tgatcgacca agattgctcc ttctccgcga acaacctcac caatcaagac cccctcatcc
    12061 tgctgcacag ttggatgaat ttgtatttta tccatatcaa cggtttgtcc acctaatttt
    12121 tcaatcatgg tgataccatc tccagttgat ccttcttgat ttgtcgtaat ataatcagct
    12181 aaatcgggac gatatttttc aataaattct ttgctggcac caaaaccgcc tgtggtaact
    12241 acgattgctt ttccggtgac ctcttttggt tcttctcctt gaacatgtac agtcacttca
    12301 ttgaccgttt ccccattttt cttaatgtct gtcacatctg cgttgacaaa aatagggatt
    12361 tcccgctcat ggacgttatt caataacccc tccactaagt atccaccaat agccgagcca
    12421 tcagacggac gatgtgtcct cttttcactc atccctccag tgatcgttaa gttgtccagt
    12481 ttgataccgt tttgatctag ccaatcgacc gcatcagcag agtgatcgac aaagtatcga
    12541 agcatttctt tatcattcgt tcctccacca ccttttagcg tttcttcata gaaggcatca
    12601 ttcgagtctt tgattccttc ttctttttga aattttgttt ctgaagcatt cataccgctt
    12661 gatgatttag atgtgtttcc tccggcaaca ggcatctttt ccaaaattac tggattcaac
    12721 ccagcatctt ttgcttcgat agctgctgcc atccctgcac caccagctcc aataatcacg
    12781 acatcataag attctttcat ttcttttgga tctgtatata cttgttcaga agcgcctgat
    12841 gatacttcgg cagattcctt cgtactagaa cttgtctgcg ctgtattttt ctgatctgcg
    12901 ccgcatgcgc tcatagcaag aagtgcaacg gctgttaata aaccagcaac taattttttc
    12961 atttgtatcc cccttttctc cttatactat attaagtgat ttttttcaca atatcaactc
    13021 tgtttttctt taagtcatat agctttggta aacacacgct tcttagtata attaaggata
    13081 tacatgaagg agttatttta tgaatcattt gaaaaccttt tttacgaaca gtacaaaaac
    13141 tgcaggtaga atcacaaacg gaatctatat tttattacgt atcatcgtcg ttattatgct
    13201 agtggatcag gtctggaacc aacactgggg aaatacaatg cttttattac tgacattaat
    13261 tttatttgaa atcccttatt ttctggaaaa gatattaaag atacagattc caaatatgct
    13321 agaaatcatt ttgttatctt ttatttttag ttcaacagtt ttaggagagt taagtgattt
    13381 ttatggctat ttttcaatgt gggatacttt tctacatgca ttcagcggat ttttagctgg
    13441 gggtgtcggc ttttcccttg tttatttgct caataaaaat acaaaaacca tgaacttgac
    13501 tcctttatta ctagcagttg tttccttctg tttttcgatg acagttggtg ttatgtggga
    13561 gtttgtggaa ttttcagcag ataaattact gcaattcgat atgcaaaaag atacgatcat
    13621 ccagcaaatc aatagtgtgg agttaagtaa agacggaaac actgtctatc atgttccaga
    13681 tatcactcgg acaatcattg aaagtcaaaa tgcagatggt aaaacagata aaacaatcat
    13741 ccaaaatggt tacttagacg tgggaatcat ggatactatg aaggatttat ttgttaattt
    13801 tattggagca gttgttttca gtgtatttgg ttacctctat agtcgaaacg attaccaaaa
    13861 atttacgttc atcaagaatt ttattcctaa aaaaatcaaa cgataaaaca tgctaaaaaa
    13921 caagagaagg ggcagtgaca atacttttgt cactgcccct tcttttttga atgtatggca
    13981 tgccattagt tatccgatag tattaactca aaaaagtaag atatgaggaa tgactatttc
    14041 gttttttatc ccaatactga ggacttattt caccatttcg ttatttatct aatttactta
    14101 aaacctgcat aactttttca taatctggat taggtgtgcc gtctagattt tcagcaataa
    14161 aagtaaaacc cattttttta taaagagcaa tcgcctgatg gctccatgtc tgtgtgtgaa
    14221 gatagattgg tccgtccgta tggagggtag gaaattcttg caagactctg gcagtcaatg
    14281 cttttgcgag cccttttcct tggtaatctg gtttcactgc taaccaatga aaaaccggat
    14341 acacttgctc tcttgatttt tttcgccaag cggtacaggt tgctactttt tctccttttt
    14401 ttgtctctac aaaaaacatc cttctttcaa gttcttcagg ataaggagca aagttttgtt
    14461 gaaaatactc aagtgcttca tctgtcgttt gaaattcccc aacggaagtc tcaatctccg
    14521 cccaagcaga ttcatcttct ttttgataaa atcgaaattc aaaaccttcc gctaaaggcg
    14581 tgattggaac attttgttga agtggtcttg tcatccagat ttctgcgtaa ggtaacgttt
    14641 tatctaacat ttttctatcc ctcctcgtct ccattatgcc aaataacata tgactcagct
    14701 acttatttga ctataacaga tagagatata aatcagaacc agtcatctgc gtcaaattca
    14761 tttcgattag cgtataccca tgttcctgcc atacctcgca tgaaatctcc taaagcagaa
    14821 gaaggaatac ctccaccagg tgcgggtgtt cccggactag gaagtggtac ttgcggctgc
    14881 agatgctcat cggtggaatc aatagttgac aagcgttttt tcttcgtttc cttctggtca
    14941 tctgattcct tctgatcttc cgactgttta gcaacaaatt ctttttctga ttgttgtttt
    15001 attttaggct ctaaaatttc attttccaat ccagaaactt gtggggccaa atgagcttct
    15061 tgccttatcg ttttattaga ttctgagatt tttctagata ttcttgctaa ctctaggctt
    15121 cttgtttgtt ttactttccc tgttggagaa actgcatgag ccatttgttg ttttttttct
    15181 gacaagcttt cttcttgtct tttttgttct ttttgatcta tctgtttgtt taatggtaaa
    15241 acatgtaata gtgactgagc atggagttct tggagtgaat acgggtcatg ataactatac
    15301 ataatcgtaa aatcacctgt ttgtttggtc aaataaccat cctccaatgg tacttcattg
    15361 attgtaaccg atacatcctt taacggtacg ggtttaccta aggaatttgt tgctgattgg
    15421 atcaactctt ctttgtttat tttttcgttt ggatgaacaa taagatcatg accttctaat
    15481 gaacgattgt ctggtatata aacataagta aaggtaattt cccctcctga ttgcttccta
    15541 ttattcatca gttctgagtg aagtacttca aggatctccg accagtgact ttttctgtct
    15601 aatccgtttg cttgcatcca atcagaaata gaagtgactt tcccattttg ttcataagtc
    15661 gataaatcta tatttggcac tcgatcagaa aattcagcag gtaggcgcaa atcaggaata
    15721 cgatttacac tactcatatg tgtttctgct tgaagttctt tatttgtttg actatctata
    15781 aaatgagtga tgacagtcga tgaagcagca gatgcttcta cataaactac agctgttgtt
    15841 tctgccacat ttgatgtttt cgagtctata taagttaata caacgggata ttctcccgga
    15901 gttgtagtat ctactgtccc gttcattttg atttcttctt tatttcctga agttccatcg
    15961 ctttttgtta catattcaac aagatcttta ggggcgtaac tctctcctgt tcttaagtga
    16021 agatcttttc ctttgatagc tgtttgatca gcacgaacat ggatcacagc agatgcagtc
    16081 attgttttta aagcaattgg atcaaaatag gacaaggaaa tagtagatgt tcctgtatta
    16141 gtcgtatcca cgatattccc attgtttgaa attactttgg acatatctcc ttgtgttcca
    16201 tctgcgttct tcagcctttc taccagatca gatatcgaaa cttttgtccc tgccagaaca
    16261 tcgattttct ttctttcaaa ctgtgaataa tctttttcat atacataaga aacttgtgcg
    16321 cttccaccgt cctttatatc tgtcaaagca tgattcaaaa tatcagtgat ctgttttaac
    16381 tgatcacctt ttgtaggatc agtcatatcg gaaaagatag aaagcggcac actgcttccg
    16441 gtttccgatg tccataatgt tttgttagga attaaccagt agtggtttat cgttggagga
    16501 taactgactt tattatagga agtcaatgca ggaagtagct gttttccatt tgcatcagtg
    16561 aaagtatgag taatagtgat aggggaatca gtggtctcag aaacagaggt acgtacgacc
    16621 ttgatggttt gtgtcgttgc ctgaacgggt acatgcatat agacacctac agataaactg
    16681 atcagcatcg tgcgcatcat aaacttaacg tagtgttttt cagaacacga ccgttcctta
    16741 tctaaacgac aagcgtgttt atttagttgt tttgaacgtc tttttgaaca catttattct
    16801 tagtcctccc tactcttgtc taaacatgaa gtagtaattt tcataagatg atttcattat
    16861 ataaataaaa tcaaaagaag atggactatt aggagagtat tttttttgat tttttattgt
    16921 ttcaagaaaa tcggaataat aacttatgta ctttttaatt ttgttaagta atatatctag
    16981 ttatatctag ttatatctag ttaccttttc tttgaaaaaa acataaatca gctaataaat
    17041 atgtgagaca aagctgccat ccataaatac tagctgattt tttcagttaa atgtctattt
    17101 ttttctctga tgatggtatt tccaaaatat tcccagtcat ctggagtcgg tggatttttc
    17161 caaattatct gttctttatt aaatttttca agtaaacaat cagataaata aatattcgta
    17221 cgagaagtga ttcgactctc aatcacaata ttgtaatttt taaatccttt cacttgagaa
    17281 ataatgtaat cggtataagc agatccttgc gaaaaatcaa tacagacatg aatcggtgct
    17341 tcaaaatatg ataccggaca aataccgacc aataaaaaga gataatcata aaataagcga
    17401 atcatgaaac gttcatcttt tcccaagaaa tagcgtttat tctcttgtat gaccttttgg
    17461 attgctgtac tgaatattgg atacgtctcg aagaaaaact gtagctgctt tttagacgta
    17521 aagctagtca tctcaaagtc gaatatccaa ttttttcgat tgacatgcat catacccata
    17581 cgaagttctt ttcgtatata tagtctttct tcttcagaga tttcaatcga aaatggtaat
    17641 tgatcaatca attccactga cattttttga ctaatcatgt ggatatcatg aaaatgagct
    17701 tccgcaagtc caaatgcgcc atctaattca aattcttctt ccgtgatcaa aaacaacatg
    17761 atataagaaa tctcatcaat gatctgctct ttagggatat gaagaaaaga aatatgtgat
    17821 aaatccttga tgatcttcat tccttctgag ctcttaaagt attcatctga aaagaaacgt
    17881 tttccgattg gttgattccc ataggccctc aacaaactaa tagtggttag caaattgaat
    17941 ttgattcgtt ttgttgcaga cagttttaaa ttgaacagat attcaaaata ttgcacgata
    18001 ctctttgctt cattcatgac gctttctcta aatggcatag aaaaaccatt aaagaccccg
    18061 aaatataccc caaataatac gttccgtatg tttatttctt ccccaactaa tatgtttttc
    18121 tttaacttta tttgatgctg ttcaagaaaa gagactaatt ctcttctttt tacataggct
    18181 cttgatatgc ttaaaaaatg attctctgca aatttttcga tcgttacttt tgaatccacg
    18241 atctccgtta acagtcgagc aatttttgat cgttgaaagt agattcttct taaatttttg
    18301 atatccgtca aattcagacg ttcgacatgg atctctgctt cttctgaaat ttggatctct
    18361 ggctttgttt tgaattcagt aaattcttta tttaattcta tgatataatt tcttgtttta
    18421 aatttagaca aacctaatgt ttcatataac ttaggcagca ctacataatt ctttttctca
    18481 aattctaaat atctagctag cagcagtttt tctctatctt cctcttctat aaggtaatcc
    18541 aacttcatat cctacacctc aaaaaatgcc tcataccaat tacttgatat gcagatgaaa
    18601 gttcatcttt tcacctatac tgattttatg atggattatg cttgtttttt catcagttat
    18661 tctcattttt tatctttttt ttgagaatat tgcaaaaaat ggaaaaattt atgaggaaat
    18721 attctatatt ttttgtttta ttgtgttaaa atgtacaaga tttgcgccat ttgcgtaaac
    18781 aaccacaaaa aagagcagga cggccaccgt cctgctcttt ta
//
LOCUS       DACGEU010000053        18711 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.053, whole genome shotgun sequence.
ACCESSION   DACGEU010000053 DACGEU010000000
VERSION     DACGEU010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18711)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18711)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18711
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.053"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            61..957
                     /locus_tag="IXR40_001764"
     CDS             61..957
                     /locus_tag="IXR40_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HAQ4361603.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            complement(1107..2048)
                     /locus_tag="IXR40_001765"
     CDS             complement(1107..2048)
                     /locus_tag="IXR40_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HAQ4361604.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            2174..3295
                     /locus_tag="IXR40_001766"
     CDS             2174..3295
                     /locus_tag="IXR40_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HAQ4361605.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            3553..5055
                     /locus_tag="IXR40_001767"
     CDS             3553..5055
                     /locus_tag="IXR40_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HAQ4361606.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            5122..5631
                     /locus_tag="IXR40_001768"
     CDS             5122..5631
                     /locus_tag="IXR40_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAQ4361607.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNT"
     gene            5860..6921
                     /locus_tag="IXR40_001769"
     CDS             5860..6921
                     /locus_tag="IXR40_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HAQ4361608.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            6924..7820
                     /gene="murQ"
                     /locus_tag="IXR40_001770"
     CDS             6924..7820
                     /gene="murQ"
                     /locus_tag="IXR40_001770"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HAQ4361609.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            7834..9816
                     /locus_tag="IXR40_001771"
     CDS             7834..9816
                     /locus_tag="IXR40_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4361610.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(9881..10327)
                     /gene="nrdI"
                     /locus_tag="IXR40_001772"
     CDS             complement(9881..10327)
                     /gene="nrdI"
                     /locus_tag="IXR40_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HAQ4361611.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            10538..11962
                     /locus_tag="IXR40_001773"
     CDS             10538..11962
                     /locus_tag="IXR40_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAQ4361612.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            complement(12143..12916)
                     /locus_tag="IXR40_001774"
     CDS             complement(12143..12916)
                     /locus_tag="IXR40_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAQ4361613.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(12913..13818)
                     /locus_tag="IXR40_001775"
     CDS             complement(12913..13818)
                     /locus_tag="IXR40_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAQ4361614.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            complement(13972..14292)
                     /locus_tag="IXR40_001776"
     CDS             complement(13972..14292)
                     /locus_tag="IXR40_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HAQ4361615.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            14766..15452
                     /locus_tag="IXR40_001777"
     CDS             14766..15452
                     /locus_tag="IXR40_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HAQ4361616.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            15454..16398
                     /locus_tag="IXR40_001778"
     CDS             15454..16398
                     /locus_tag="IXR40_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HAQ4361617.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            16597..17241
                     /gene="pcp"
                     /locus_tag="IXR40_001779"
     CDS             16597..17241
                     /gene="pcp"
                     /locus_tag="IXR40_001779"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HAQ4361618.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            17320..18597
                     /locus_tag="IXR40_001780"
     CDS             17320..18597
                     /locus_tag="IXR40_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361619.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
BASE COUNT         5995 a         3304 c         3988 g         5424 t
ORIGIN      
        1 tttttactat ttaaacaggc tatcatagga aaaagtgaca gagaaagtga ggcggaaaag
       61 atgaacaaaa atgacgtact gctagttgca aaaaataaat cactttattt tttgccttcc
      121 atccgctctt tagatgtttg gtccggaaaa gatttactac agtcggaatt cattaaatca
      181 gctagacaac agttggcaaa ttatcagctg atcgtttttt tagattatgg atttgatatg
      241 gagatggctc gacgcgtgcg cccatttacc aatgcaaaaa ttgtgttatt tttttggaat
      301 cacttcaaag cagaacacga ggcgatgctg aagcaggcac aagatgaacc ggcaatcgat
      361 gagatttatc attttgattt tttggaagca aaagaacttg ggctgaaaca taatagttca
      421 ttttattcga aacatatgaa tttttcttct agcgaaccaa agacggatct attttttggt
      481 gcaacgaata atgggagaaa agaacgagca gaaagctata agcaggaatt tataaaaaga
      541 gatgttacga ccaactattt cattcttcca catcgaggga atgaacaacc tggatatctt
      601 acttatgaag agtacctgaa aaaaacaggg gaatcgcgcg ggattctgga actgttgcgg
      661 gagggtcagc aaggagtgac tttgcggaca tttgaatcca tgtattttca aaagaaacta
      721 gtgacggata atcaagcgat tgctcattat catttttatc gtcctgaaaa tatttttttg
      781 cttcgagaac gtgatttaga tgaattaccg gaatttctgc atacaccatt taagccaatc
      841 ctatcagagc tattggaatt ttatgatgca gaaaattggg caaaacgatt tatcactaac
      901 gattccacta tttatgagca atacgaatat gacctctcct ctgttgaaaa caaataaaaa
      961 acctacattt tgaagagatt atgtactgaa acaaacaagc acaattctta tggcatcatg
     1021 agagttgtgt tttctttttg atcttttatt gggcttaaaa aaagagaacc agctgctgat
     1081 tcagctgatt ctcatcagag agccttttat tctgcgccaa ggattccttc ttttgcatgg
     1141 actaattggg tcaaaaaggc acaatatggt gtagcaatat catatttttg tccttttcgc
     1201 caaatggcac cattgatgta gtcgatttca gtcaaacgat ggtttttgat caggtcttgg
     1261 tacatagatg ggtaatgcaa cccgatgttg tcaggatcat aagtagaagc aatatgttgg
     1321 tacacttctt cttgatctag tatgattcct tcttttgctg cgatagaagc aaattcagat
     1381 acgattgttc gaaccatgct ctctgccgct ttttgcgcgc ctagttcagc aatattacaa
     1441 tccaaaatcg tgcataaacc attcaatgtt ccatttacac aagcttttcg ccaaatggaa
     1501 taacgaacgt tatggctata gatcggattt aaatttgctt cttgaaagac ttctacaact
     1561 ttttttgtaa atgcttcgcc ttctggttcc aagttctcta gttcgatttc tccatcacct
     1621 aacaatgtga cttttccggg accagctaga ccagctgtcc acatcgtgat cccaaataag
     1681 atatttttct ttggcacata tttttccagt acatcttcat gacctaatcc atttagtaaa
     1741 cacaaaacat aagtattgtc agtaataatg gattggatcg aacaaaacat atcatctaat
     1801 tgattggctt ttgttaatgc tacgatcaag tccacgtgtt cgttgctttc gatgatttct
     1861 tctggtgaat agattggcag ttttgcgacc acttctttac cgttaaagtc agcaatcaac
     1921 ccatttgtac gaatggcttc aatgtgagca ggccaacgat cgatcaagag gacctcattt
     1981 ccgctttgat gtagcatcaa tccgattcgg ctgcccattg ctccggcccc agctattgcg
     2041 attttcatgt tttttctctc ctttattcaa tgagttccct tttagtatat agaaaaatgg
     2101 aagaaaatag cattgttttg tttgaaaaaa atgaaaaaaa gtgtcttact taagaagaaa
     2161 gtgagggata cagatggata ttttggcggc aattgattca tttaaaggaa gtgcttcttc
     2221 atttgaacta aatcaggcag ttctaaatgg ctgggaagat cgtaaaggaa gaaaaatcaa
     2281 tgtgccgatt gcagatggcg gagaaaatac tgcagaagca atctattacg cgctcagggg
     2341 aacatggcgt accattgatg ggatggatct cttattccgt cagcgaaaaa tcagctattt
     2401 attgacaact tggcaaggaa aaaacaccgc agtcatcgaa tctgcacaag cattggggtt
     2461 agatctactt gataaaccaa cggatcaaac tatccgactt gcttccagtt atgccttagg
     2521 agaacttatt aaagatgcac tgcttcaaga agtagaacaa attattgtca ctttaggagg
     2581 aagcgggtgt agcgatggtg gtctaggatt actccaatcc ttgggtgctt ctttagaagg
     2641 gtacacagaa ggaaatcctt tattatctac taaaaaactt cattttgatc gaagaaacgt
     2701 tcttgtttct aaagtaaaat tgattatcgc tgcagatgtt accaatccat atacaggtca
     2761 acaaggagct gcttggcaat ttggaagaca aaaaggagga atagatacga cgctagcttt
     2821 cttagataaa caagcaggaa agattgctca gcaaataaaa gatttctggg aggtggattt
     2881 agatgatatt ccaggaagtg gagcagcagg cggtattggt ggagcccttt ttttgttggg
     2941 agcgaagatg gtttctggtt tcgatttagt cagccaaatc actggattgg aaaaaaagat
     3001 cgaacaagca gatgtcatca ttacaggaga agggcggatc gatcagcaaa cgatccacgg
     3061 aaaagttcca tacggtgtag cagtgcttgc aaaaaaatat cgaaaaccaa taatcgctat
     3121 ttgcggaagt agagaccaag agctagaagg actttctgat tttctcccaa ttgtcttaag
     3181 tattcatttg ggtccaatag gtttagaaga agcaatggaa cacaggcaaa cattagaaaa
     3241 aacaaaaatc ttaggacaga cacttagcag atttttcacc atcctcccga agtagttgac
     3301 aaaatcattt tctttatgct atcgtaattt caaatatagg acaaagtgag ggatccgtgc
     3361 attgaaaaat taagtcgatt gatgaaagct gcattcagac tgtaccttgt ggagacaagg
     3421 aagcagtgtg cagattttcg ggattggctt ggttttttcg atgtatgggt ctttttgtgt
     3481 gtatccaacc cttgcatcct ctttagccag ttctgaaaat aggactggtc tttttttacg
     3541 aggtgatgga aaatgtctaa aatcgaaata aaaaatctga cattcggcta cgacagccaa
     3601 ggcacattat tatttgaaca agcaaatcta aattttgaca cacaatggaa actaggactt
     3661 atcggacgaa acggtcgagg aaagacaact ttactgaata ttctacaaaa caaactacct
     3721 tatcaagggc aagtaatcca tcagcaagaa tttgcctatt tcccgcaaca gacaaaagat
     3781 aaagaacgtt taacctatta cgtgttaaat gatattacgg attttgagat atgggaaatc
     3841 gaaagagagc tccaattgat gcaaacagat cctgaaatct tatggagaga attcagcaca
     3901 ctatcggggg gagagaagac aaaagtccta ctggcacttt tatttgtgga tgacactcat
     3961 ttcccgttaa tcgatgaacc aacgaatcat ttggatatct ctggtagaaa acaagtagcg
     4021 gcttatttga aaaagaaaaa acaaggcttc atcgtggtca gccatgaccg gggatttatc
     4081 gatgaagtag tggaccatgt tttagcaatc gaaaaaagtc aactggaact ttatcaaggg
     4141 aatttctcta tctatgaaga acagaaaaaa cttcgtgatg aatttgaaat ggctcaaaat
     4201 gaaaaattga aaaaagaagt cagtaggcta aagaaaacag cagctgaaaa agccgaatgg
     4261 tctcgttccc gagaaggaga taaaacaaag aaacaagtcg gattcatcga tactgaatct
     4321 agacgagtga ataaaggagc agtgggtgct gatgctgcac ggacgatgaa acgatccaaa
     4381 gcaatcgtga atcggatgga gacccagatc agcgagaaag aaaaactatt aaaagatatc
     4441 gaatatatcg attctttgac gatgaatagc caagcgtctc accataagcg acttttaagc
     4501 gtagaagatc ttcaattagg gtatgaaaat ctgttattcg agccaattca ttttacaatc
     4561 gagcctcatc agcgggtggc gatttcaggt cctaacggtg caggaaagtc atccattatc
     4621 cattatcttc tgggggcatt caacggcaag gttataggag aaaaatacca gccaaaacat
     4681 ctgagcatta gttatgcaag ccaaaattat gaagacaatc gaggaacgtt ggcggaattt
     4741 gcagagaaaa accaagtaga ctaccaagca tttttgaaca acctccgaaa gcttgggatg
     4801 gaaagagatg tttttcataa caagatcgag cagatgagta tgggccaacg gaaaaaagtg
     4861 gaattggcta aatctttatc acagccagct gaactatata catgggatga accattgaat
     4921 tatttggatg tcttcaatca agaacaatta gaacaactga tcttgaacgt gaaacctgcc
     4981 atgttactag tggaacatga tcaaaccttc ctggataaag tatctactga gattatttct
     5041 cttgagagaa tctaaccctt gtaatctcaa gaacaacaag gtatggttaa ggggaacttt
     5101 gccaacgaag gagagaatca catgctttat gtaacgagac acggagaaac aacttggaac
     5161 gcacaaggat tagtttgcgg acgggcagat gtgccgctga ctgaaaaagg acagatgcag
     5221 gcacagaaac tagcagaaaa ggtagtagat ttgcctgttc caatcacgaa aatcatccat
     5281 tcccctcttc aacgagcaag agatacagca caagcagttg ctgatcgtct cagcttgccg
     5341 ctgaccgttg atgaacgatt ggtagaaatg gattttgggg attatgatgg actgccaagc
     5401 aaagatgaga actttcaaaa agcacgttta gcgttcgctg tacgattccc aaatggggag
     5461 tcagtcttag atgtgtatgc acggatcgtt cctttattga aagaatgcat cgaagacgaa
     5521 gaaaatgtct atctgttagt ttgccataat gccttgataa gagtgatcaa tgcttatttt
     5581 catccgatgc ctaatgaggg gttctttaca ttcatggtag ataatacata attggtttct
     5641 tatgagtaat tatgtttttg tgttatttaa ataaaatatt tcaaggcact gcttttgctt
     5701 agcagtgcct tttttaggtt atgacaattc ttttgataat ataaactcaa cctttagaaa
     5761 tgaaatttaa ttattttaat aaaagtattg aaattttgtt tctttagata tatactctag
     5821 tcatagaaat gaagacggat acagaaaaag agggataata tgtttggctt ttcaatattt
     5881 atgaacgatt ctttgtcaga agagaagaaa cagtatatcc gccaaatggc atccaatggc
     5941 tttgtcggta ttttcacttc catgcatata ccagaagatg atgtttcggc atatcaaaag
     6001 cgattgatcg aactaggaag cgaagcgaaa aagaataaac tagaattgat ggtcgatatt
     6061 tcaggagagg cattggaacg agcgggtttt tcattagaag atctaacgcc tttgaaagca
     6121 attggtgtaa caggtttaag aatggattat catatttcca atcagcagat tgccgactgg
     6181 tcacatcaat tgaaaatcag tttgaatgct agcacgatca cgcctaaaga tatcgatgaa
     6241 ttgaaagaag cagaagctga tttctcacag attgaagctt ggcataatta ttatccacgt
     6301 cccgaaacag ggctggacaa agaatggtat cagaaaaaaa atcaatggct caaaattcaa
     6361 ggtctccttg tccaaggttt tgtaccagga gatacagagt tgagaggccc actatatcaa
     6421 ggattgccaa ctttggaaga acatcgaggg atccatcctc ttgcaggcgc tctagatcta
     6481 ttagcaagta acacggatat tgtttacatc ggagatgcag gtctgtcaga aaacgttcag
     6541 gagcaatttg cttctttcca aaaagaacag acagtcttgc tccatacgga acctgtagat
     6601 gaagaatttt acgaatatat attagggaag catacgaatc ggcaagacga tgcaagagat
     6661 gtcatacgaa gcgtagatgc acgttttcga gagattccgc ctatcccagc aagaaataca
     6721 gctacgcgta tgaaagggtc tattacttta gataacgaaa agtatttgcg ctatatgggt
     6781 gagatccaat taaccaaata tgatttgcca gcggatgaaa aagtgaatgt agtagctaaa
     6841 gttatcaaag aagagctacc attgatcaac caaatcaaag ctggtatgaa ctatcaattt
     6901 ataagaaaag aaggaagata aaaatgagca aaatcaattt agagaaccta acaacggaac
     6961 gcagaaacca agaaactttt ggattagatg agatgagtat ttctcaagcc gttcaactaa
     7021 tgaacaaaga agatcagaaa gtggccgctg cggttgaaaa agaactgaca agtatcgaac
     7081 cagtgattgc taacacgatt gagtccttta aaaaaggtgg acgtctgatt tatatgggag
     7141 ccggaacaag tggaagacta ggtgtgttag atgctgctga atgcgtaccg acattcggtg
     7201 tagaaccgga aatggtcata ggtctaattg ctggtggaga agaagcaatg actgtagctg
     7261 tcgaaggggc cgaagattct tatgagctag ggcaagaaga tctaatcaag ctgaatttga
     7321 caaaaaatga tatagttatt ggtatcgcag ctagcggtcg tacaccatat gtgatcggtg
     7381 gattagatta cgcaaaatcg atcggtgctg tcacaggaac gatttcttgc aataaacaag
     7441 ccgaaatcag taaacacgcg gatttcccaa tcgaagtcga tgcaggtcca gaatttttga
     7501 caggctctac tcgattgaag tcaggaacag cacaaaaact tatcttgaat atgatttcta
     7561 ctatcagtat gattggtata ggtaaagtat tcaataactt gatggtcgat gtcaaaccaa
     7621 caaatgaaaa actaatcgaa cgctcaaaac gaatcatcat gcaagcgaca gaagctgatt
     7681 acgaaacagc tgaaaagtac tttgaagaag cagatcaaaa tgttaagctg gctatcgtca
     7741 tgattttgac aaatagtgat aaagaggaag ctcaagcaaa attagctgaa gcaaacggat
     7801 ttgtaaaagg gaccttatga gggggaaaag accatggcaa aaaacgaact gactttggaa
     7861 gaactggcaa aacaaattta taaaggggca ggcggcatgg gcaatgtaga aagcattgtc
     7921 cactgcatga ctcgtgtgcg tatgaagatc atcaatgatg atcttgtaaa tgtctctgaa
     7981 ttaaaagcga ttccaggagt gcttggtgta gtagaagatg aacagcttca agtcatcatc
     8041 ggacctggga aagtgaacaa agtagcacag caaatggttg atttggcagg cgtgaaatta
     8101 ggagaaaaac tttcttctgt aagtacagct acagcaaatt catcagcatc tggaaaagac
     8161 cgtgtaaacg aacgggcaca agaaatgaaa gcggcacaaa aatcgaaaca aaaaccatct
     8221 aaaatcaaat cggtattaaa agacatttct aatatctttg tgccaatgat tcctgcattt
     8281 gtcggtactg ggatcgtggc agggattgcc gcagttttag caaacttagt cacagccgga
     8341 acacttgatg cagcaacatg gcaacaatat atcgatgtga tgaacatctt gaaaaacggg
     8401 atgtttagct acctagttat ctatacaggt atcaatgctg cacaagtttt tggtgcaaca
     8461 ccaactcttg gtggagttat cggggccgtt gtgatgctga cagggatgaa tccggaagca
     8521 ccactgaaaa acttatttac tggtgaagct cttgcagctg gacaaggtgg gatcctaggt
     8581 gtcatcttcg ctgtttggct attgtcaatc gttgagaaaa aactgcataa agtagtacct
     8641 gatgcggtag atatcatcgt tacaccaact ctttcattga ttgccatcgg tctgattgaa
     8701 attttcttca tcatgccttt agcaggtttc atttctgatg gcatggtcgg tgggatcaac
     8761 tgggtacttg gcgttggtgg agcatttgcc ggcttcgttc taggcacatt attcttgccg
     8821 atggttatgt tcggactgca tcaaattttg actccaatcc atgtgcaaat gattgatgaa
     8881 actggtcgta cgctattgct tccaattctt gcgatggctg gtgcaggaca agtgggtgca
     8941 gcattggcat tatggattcg ctgcaaaaaa gataaagaat taacagaaat gatcaaagga
     9001 gctttaccag tcgggatcct aggaatcggc gaaccattga tttacggagt aacattacct
     9061 ctaggacgcc catttattac tgcttgtatc ggtggaggta tcggcggggc agtgatcgga
     9121 atgatcggaa atgtcggggc tatcgctatt ggaccttcag gagccgcttt gatcccattg
     9181 atctctgacg gtaaatggtt aggctacatc cttggattat tggcagctta tgctggtggc
     9241 ttcgttgcta cattcttctt cggtattcct aaagaccgtt tagaaaaaga agaattagcg
     9301 actgaaacag ccacagtaaa tgaagtgcct gaaaaagtag tacctcaaac ttcagctgaa
     9361 agtgtgacta tcctctcatc agttgctgac ggaacagttg tttctttaga taaagcaagt
     9421 gatccagttt ttgcacaaaa gatgatgggt gaaggctact ttgtagaacc agaaaacgga
     9481 catatctatt ctccagttac tggggtagtc agctctgtct tcccaacgaa acacgctatt
     9541 gggatcacaa cgccaaatgg tttagaaatc ttgcttcata tgggaatcaa cacagttgac
     9601 ttaggcggta cgccatttga tgtgaaagta acagaagggc agcaagtgac acctgatacg
     9661 cttgtagcag aagctgactt agaagcgatc aaagcagcag gcaaagaaac atccatgatc
     9721 gtcttggtaa ccaatatgga tcgtgtaaaa aactttgtct tggaaaaaac aggtaaagca
     9781 aaagcaaaag cacctgtgat ggatgtcaaa gcttaatatg atagaaacaa tagaaacgaa
     9841 agaagaaact gaaatctatt tttcagcttc ttctttttta ttatttattg ttttctgcta
     9901 aaatctgata aattcgtgtc acatcagatg gtgttccccg taattcataa tctgccaaga
     9961 aaggaaagcc aaatgtttgt gcatattgtt tggctgttag acaatactga ttattgaagt
    10021 ttttatttcc gctaccgact acaccaagac aaagtttatg attgtcttca tgttccagat
    10081 attcacgcat cgtttcggtc aagatttctg tatcaccgtt atctaaacca tttccgccgt
    10141 ctaaataagt aggaacgaaa gtaaaaaatg gttctgtttc tttcgtaaaa tcactatttt
    10201 catggatttc ttttaaagta acttcaggat tgacaggatc ttctgcatgc attttttcag
    10261 catattctgc tagatgtttg gcaaaggcac gcgtatttcc tgaaatcgat atatataaaa
    10321 tgttcatgga tcatcctcca attctttcct tttagtatag catctttttt aagttttttg
    10381 gtggtgtaat ttggaaaggg actaggcgct ttgcttgtat aatgagaaaa aagccggtag
    10441 aattatattt ctattaaagt ttttattaat taagtaaaaa taaaaaaggt ttgttatact
    10501 ttttgataaa agcggtttta ttttggagga tgcttacatg gatacagagc aacagaaaaa
    10561 aggaattggt ttaattccac ttgctgcctt agtaattggt tcagcgattg gaggtggcgt
    10621 atttggtatt atgacggaca tctccggatc ggctggcggc ccagctattt tcagttgggt
    10681 actcgtagga acagcaatgt tgatgctctc cttgtcgatc aataatatca ataaaaaacg
    10741 tccagattta aaaggcggga tctttagtta cgcagaagaa ggttttggcc gtttcgctgg
    10801 ttttatcagc ggttggggtt actggctcac atgctggtta ggcaacgtag cttttgcaac
    10861 attgttgatg agcgcattag gatatttctt cccagtattt gaaggtgggc aaaatctggc
    10921 atcgatcgtg atgagtacag tctttttatg gggatatgca tggctagtga atcggggagt
    10981 cgaaaatgct agtttcgtca atgctatcgt cacattctgt aaattagtgc cattattttt
    11041 atttattgta gtagctatca gcacgttttc gatccaacaa ttcattgata acttttctag
    11101 cgacattata ttgaatgcga atggacagcc gatcccgttt tccagtcaag tattgagttg
    11161 catcatggtg atgctttggg tatttgttgg tattgaagga gcctctgtcg taggttcacg
    11221 agcaaaaaaa caatcagatg ttgggaaagc aacgattcta gggatattcg gcttgattat
    11281 tatttacgtc ttggtttcca tgcttccata tgggacaatg acgatgaatc agctgcaaac
    11341 gatcaaggcg cagcctgcta tgggctatgt gtttgaaatg atggttggta aatggggagc
    11401 agtcgtgatc aacggcggtt tgatcatttc tttagttggt gtttggctct catggacgat
    11461 cttaccgatt gaaacaatgg gaaacatggc tgaagacgga cttttgccta aagcatgggg
    11521 aaaactcaac aaaaatgggg caccaactta tgctatcgta ttgacgacgt tatgtacgaa
    11581 tgtcttttta ctttcattat tattcactga cagtgcttat aactttgctt acacacttgg
    11641 tacagcagct attttcttca cgtggctttt cttaggattg taccaaatga aactttctta
    11701 tcagcggaaa gaatgggtcc aatttttagt agggctttta gcaagtgcct ttcaagtatg
    11761 ggctatgcta gtcgtagcct ttaatgaagt aatgcttgtt cttgttcttt tcttgccagg
    11821 catttatttt tacctcaaag cacgtaagga gcaaaacgag cctgtacaac atatccactt
    11881 agataagatt ttacttatag gtgtgacgat ggtcggagtg attgcaatgg ttttatttgc
    11941 cactgggatg cttcacgtat agaagtataa aagaagtata aagagaggtt gtgagcctgt
    12001 cgtttattca aaaacatact aggaaaggag ctgtgacaca aatgttgtca cagctccttt
    12061 ttcagaataa acggtgttta agagacagcc aatcggcaat aaggctgaac gtctctttca
    12121 cagcctcttt tttgatgagt catcatacat tttttcgctt aaatacgaga tatcctaatg
    12181 ctaagaacaa aacgatgtaa gctaaattac cgaatagcat ttgattagta gaaagatgag
    12241 tcaattgctt catgatctct tcgtttccaa tttggttttg cagattcaac atactgatcg
    12301 gattccattt gatccactcc catttttgga tgagtgcaat aaggatacca gatatgattg
    12361 acgaagcaaa ataaaagacg attcctgctg agatggatgc gccggaacta ttgataaagc
    12421 aagcaatcat caacactaaa cttaaaatca gccataaacc gatataacta cccaaagtat
    12481 aagtgaacaa gctttggatc agtgtttgac cagtagaaac cttctccgtg aaggaaatcg
    12541 aagggaaaag aatcagtttc atcaacacag tgacaataat agctaaaagg tataaataaa
    12601 cagaataaat aactaatgtg atccatttgc ttactaatat ttctcctcga gaatactttc
    12661 gataaaggag atttttcaat gtaccatatt gtgcttccat cgaaatgatc gtgcttgcag
    12721 ctgcaatcat gataaagaca atccaagatg tggcactaaa aagctgagca gtcatttcaa
    12781 ctggatcaat gatcgtcgtg tattttttgg ctagaagtgc tgttcctatg agcaaaacaa
    12841 ctaatagaac agataaaaca gcagttgact ttttcttgat caatttaaat aattcttgtt
    12901 ttacaagcaa tgtcattttt cttcttcccc ctttactgaa tccagaattt ccaatagaga
    12961 agattccaaa tcattcgtca gatgctggac gtctgtcaca tggatatttt gtgcagacaa
    13021 tagctggatc acggttccta ataattcttc gttttctttt aaaagcttga ttttatcagg
    13081 atcttccaaa gtatatccag cttctgtcaa gatcgttcga gcagctagat catttgttgt
    13141 agagataacg atgaaatctt gcgctgtttg gttcaattca gccattgtac attgtttgat
    13201 gatctttcct tgattgatca ggatcagctc atcgaccatt ttttcaagct cgctgagtaa
    13261 gtgactggag atcaagaaag aggtgccctg agtagccaag tcggtaatga tttttcgcac
    13321 atctcttgtt gcttgtggat ccaaaccgtt catcggctca tctaaaataa cgatagacgg
    13381 atggttcagt aaggcaagag caattcccaa tttttgtttc attcccaacg agtaggattt
    13441 cgcttttttg tgaatgtact tttccatctt gagctgattc acgatagtgt cgatagcaga
    13501 tacatcgttg gtttcagaga ataacttcag atgatcatag cctgttaaga atggatagat
    13561 acccgggtat tcgatcaatg ctcctacttg ttccaaccct ttatgactag agggagaaat
    13621 ctcattttca ccaatacaga ttgttccatc tgagtaatgg atcagtccta aaatagcttt
    13681 catgatcgtt gtttttccag cgccattagg acctactaat ccaacgattt tgccagggga
    13741 taagctaaaa ctgacatcgc tgagggcttg tttgtgacca aagttcttgg ataattcttg
    13801 gaccgaaaga cttttcaaaa atattcactc cttttctata gatagtacaa gcatacacct
    13861 gatgagtgga gaagtcgcta ggtcattgga cttatttctt attttttcat aaaaaaattg
    13921 aatattaaat aaaaaggctt attttttctg atcagtactt attccaagtg tctagtggcc
    13981 gctagtaatc ttgatgccaa tgatactgat gagtagcatc cccacaaaga accaagtgga
    14041 aagattcagc ttatcatgaa acaagaccac accaattatg accgaaccaa ctgcgccaat
    14101 ccctgtccag ataggataag agagactcat cggcaaactt ttgattgcct ttgacaaaaa
    14161 gtaaaaacta gcaatcatgc caatcactgt gtaaaaagaa taattgattt tagaaaaacc
    14221 atcactccat ttcatcatcg ttgaccagaa tacttccaaa attcctgcta tgattaattc
    14281 catccatgcc atacttacat tcctccttaa ctataaaaaa atacacaaaa agaggaaaat
    14341 catcccttca aagacctaat ggaatgatca tcctctttat cctacccggt ggcagattgt
    14401 atatcttttt ctgtagtata gcacacctat ccagatatcg gcaatctcat actttttagt
    14461 aaagtgtacc aagcactgac ggatatatcg ttagcggaaa agaagatgaa tgctttgcaa
    14521 tttcatagaa agaagttgtt atttattaat catttaaaaa aaacagtaac tagaccttat
    14581 ttctatatat tatcgggcaa taaattaaaa aaagctttac cttacaataa gtaagataat
    14641 ttttgtgata aaaaaataac gaaaaatatt taaaaatagt gtctatttcg tgagaaaaca
    14701 actatatttt ttatgtgttt tgctttataa ttaaaaaaat attgtcattt tatggaggaa
    14761 aatatatgga aaattatctt agccttttag gcgtcttgat tgttattctc gggtttgcat
    14821 ttaaattaga ctcgatattg atcgtaatgg ttgctttagt tgttacagct ttgactggcg
    14881 gtcttggcat tcaaggaatg ttagaacttt taggtacaag ttttgtaaac aatcgcggga
    14941 tggcgatttt tatcatcatt atgttggcaa caggaacgct tgaaagaaat ggtctgaaag
    15001 aatcagcggc ttccttgatc aagcgattca agaaagtatc tgctggtatg attgtagata
    15061 tttatgggat ctttcgaatg atctttgcgg cttttaacgt gagttttggt ggagttgctg
    15121 gatttgttcg tccaatcatt ttaccgatgg cattggggac catcgaatca aaagggttag
    15181 aagtccatcc taagcatgaa gaagaactaa aaggtatggc ttcagctatg gaaaatgtct
    15241 gctggttctt tggccaagta ctattcatcg gaggagcagg ggcgttgcta gtccaatcaa
    15301 cactgaaaga tctaggatat gacgtaacat tgggacagct tgctttagtg gaagttccag
    15361 tggctatcac ggctttagtt gtggcaagtg tctacttcta tcttaaagaa aagaaattag
    15421 cgaagaaata ttatccagga aaggggcaat aagatggact tttttacaaa tcctgatatt
    15481 ttattaggcg ataaattact ggagatcctt tatatcgtga tgggactcgt attgatttac
    15541 actggagtaa gaaatttaac agataaaacc aatcctcatc gttatgggtc agcctttttc
    15601 tggacggtct taggggtagt tattgcagga ggaagatggc ttccggcaat cgtgaacggt
    15661 ggcttgatct ttgcgatgac cataccagca attgctaaga aagtcagcaa aggagaaagc
    15721 cggcttccat caaaagaata tatggaaaaa atgtcagaca aactaggaat gaaaattttt
    15781 attccagctt tgagtatcgg tgtctttgcg atcttgtttg ctctatttac caatttaggt
    15841 gctttagtcg gcgtgggcgt cggtgttttt gcagccatgc taatcttgat gttcttttct
    15901 cgagataatc gaccaagtac atttttagat gatgcagcag atatgctggg cacagtaggg
    15961 ccgttaagca tgttgccaat gcttttagct tctctaggtg cggtatttac aagcgctgga
    16021 gttgggacag tgatttccaa tgcagtaggt acgatcgttc cagaaggaaa tgtgaacatc
    16081 ggcatcatca tttacgctct tggcatggtg atatttacgg taatcatggg gaatgcattt
    16141 gcggccatca ccgtgatgac ggttgggatc ggtgcaccat tcgtatttag tcatggagcg
    16201 aatccagcgt taataggaat ggttgcattg acttgcggtt tttgtgggac cctgctgaca
    16261 ccgatggctg ctaacttcaa tatcgtgcct gtagcgatgc tggagatgaa agacaaatac
    16321 ggagtgatca aaaaccagtt gtttattgcg ttatttatgc tagttttcca aattgcttat
    16381 atgattctat ttaaataata gaagagaggg gttgtgacag aataattgtc gcaacctctt
    16441 ctaacattgt agtggaacac tattttttta taagaatata ttaagtttga tctgttatgt
    16501 tatttaaact attgtttcct ttatttacgc tgttcaagga aaatggtatg ataaaagata
    16561 accatatgtt aaatcaatcg gacggaggaa caacagatga aagtactagt aacaggtttt
    16621 gatccatttg gtggggacaa agtgaatcca gcctatgaag cagtaaaaaa aatgccagat
    16681 gaaatcagcg gtgctgaaat catcaaagtg gaagtaccga ccgtattcga aaaaagcagt
    16741 caagtagtca aagaagccat ccaacagcac caaccagatg tcgtgatctg tgtcggacaa
    16801 gcaggtgggc ggtcagcagt ctcgttcgaa cgtgtcgcaa tcaatctagc agaagcaaga
    16861 atccctgata atgaaggaaa tcagccattc gatacggctt tagaagaaaa cggtccagcc
    16921 gcttacttta cctcattgcc aatcaaagca atgacaaaaa atgtacaaga tcatggtcta
    16981 ccagcgtaca tctcttatac agcaggaaca tttgtctgca atgatatcat gtatcgtttg
    17041 cttcatttga tcgaaacaca attcccggca attcgaggtg ggttcatcca cgtgccattc
    17101 tcacccgatc aagtgatcga tcgtccagtg ggtacgcctt ctatgtcttt agaagacatt
    17161 gcttcttctt tgacttatgc agttgaagca gcagtagaaa ataaagaaga tatttccgga
    17221 aatgccggaa caactcacta atttagcaag aaacactggc tggttgctaa cgttatgtta
    17281 gtagccagct ttttgtaatt agaaaggaaa gaaacagccg tggaagaatg gcaatccgtc
    17341 tttgaagaat ggtttccaaa agaaatcagc aaaagctatc ccatcaaaat ttctaaacaa
    17401 tacacaagca gtcaacgttg ggagatctat gcaaaattaa cgaaaaaaca gcgggaacta
    17461 gtcgataagc accgccgata tctaatcagc tctcgtttta tggaagaaca ttatttagct
    17521 gcaacagatt gggtgttttc tgacttcaag atcaatccgt tttttcgaac aaaacgaagc
    17581 cagcaaaaat tgtattgtga gtgtggtaga gaattaaaag tgcaatacat cgttaaatcg
    17641 ccaaaaaccg gaaagatcct aaaactaggc atcaaccact ttgccgatca cctgcatgtc
    17701 tctccgacag tggcagcttc gatccatcag ggaatgacaa aagttgatct ggccttagac
    17761 gaattattat ggcttaagca gaagaatatc gattttcctg aaggactatg gcaaaaatac
    17821 tgttttgtct tgtaccaaaa tcgtcggatg aaacagccat atttaccgga tataaaatta
    17881 gctcagcggc tcgcagaatt tcgccaagta gaaatgccga tttacatagc ggattatcaa
    17941 gcattggaaa atgaaatcaa gaaaataagt gaacacatca atgggcagtc aaaaaagcga
    18001 cagataaaaa aagaactatt tgacgacttt gcagaagaat tagtaaagga tgtagaagaa
    18061 ttcttgatca actatcgcgc atttttacgt aaagattggc aatccatcgt atatgaagaa
    18121 gtgccagtac atcctaatgc ttattttgaa acatttattt ccgtgttgag aaagacaaaa
    18181 cgtcaacgaa caccagaagt cactgctcag atggaatatt ttgcgaaaaa ccaacgattc
    18241 atccaaccaa aaatctatct atttatttgg aagcaatatt gtcgctatgg ttttacagaa
    18301 gggttcttcg acagcattcc tcggatagtc agaaatggtt ttttaaaagt attgcgtaaa
    18361 gaacgagaag ctatacaatc tgctgataag aaagaccgta cagtctcaaa agaaaaatgg
    18421 caactagtag tgaaagatat ccaatctgga aatgtgcaag agacaatcga caaatggaaa
    18481 ggaaaacatt atcgttttac tgaagctcag aaacaagcgt tggaatatta tcagaagtta
    18541 gaagaatcac tgcgtttcaa tgatgaggca agaaagtatc tgaaggaatt actataaaaa
    18601 acatactaag attagagggg aacatcattg acgaatgatg ttctcctcta ttttctattt
    18661 ttagattata gtgaagagtg aaagaaagtt cgaacaaagc cttgaggact a
//
LOCUS       DACGEU010000054        18494 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.054, whole genome shotgun sequence.
ACCESSION   DACGEU010000054 DACGEU010000000
VERSION     DACGEU010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18494
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.054"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            99..746
                     /locus_tag="IXR40_001781"
     CDS             99..746
                     /locus_tag="IXR40_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HAQ4361620.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     gene            1139..3784
                     /locus_tag="IXR40_001782"
     CDS             1139..3784
                     /locus_tag="IXR40_001782"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HAQ4361621.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            4094..5407
                     /locus_tag="IXR40_001783"
     CDS             4094..5407
                     /locus_tag="IXR40_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HAQ4361622.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            5397..6050
                     /locus_tag="IXR40_001784"
     CDS             5397..6050
                     /locus_tag="IXR40_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAQ4361623.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            6105..6797
                     /locus_tag="IXR40_001785"
     CDS             6105..6797
                     /locus_tag="IXR40_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="JAB domain-containing protein"
                     /protein_id="HAQ4361624.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGNVIPSQQDMNFTKRIQKCGEMMGITVLDHLIIGRKRY
                     FSLREEGMMEEK"
     gene            6947..7147
                     /locus_tag="IXR40_001786"
     CDS             6947..7147
                     /locus_tag="IXR40_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAQ4361625.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
     gene            complement(7401..9080)
                     /locus_tag="IXR40_001787"
     CDS             complement(7401..9080)
                     /locus_tag="IXR40_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HAQ4361626.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
     gene            complement(9082..9294)
                     /locus_tag="IXR40_001788"
     CDS             complement(9082..9294)
                     /locus_tag="IXR40_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HAQ4361627.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            9687..11417
                     /gene="efrA"
                     /locus_tag="IXR40_001789"
     CDS             9687..11417
                     /gene="efrA"
                     /locus_tag="IXR40_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HAQ4361628.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            11414..13174
                     /gene="efrB"
                     /locus_tag="IXR40_001790"
     CDS             11414..13174
                     /gene="efrB"
                     /locus_tag="IXR40_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HAQ4361629.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            13269..13466
                     /locus_tag="IXR40_001791"
     CDS             13269..13466
                     /locus_tag="IXR40_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361630.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            13619..14104
                     /locus_tag="IXR40_001792"
     CDS             13619..14104
                     /locus_tag="IXR40_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HAQ4361631.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(14208..14801)
                     /gene="clpP"
                     /locus_tag="IXR40_001793"
     CDS             complement(14208..14801)
                     /gene="clpP"
                     /locus_tag="IXR40_001793"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HAQ4361632.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            14981..15508
                     /locus_tag="IXR40_001794"
     CDS             14981..15508
                     /locus_tag="IXR40_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAP domain-containing protein"
                     /protein_id="HAQ4361633.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            15599..16336
                     /locus_tag="IXR40_001795"
     CDS             15599..16336
                     /locus_tag="IXR40_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HAQ4361634.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            16340..17257
                     /gene="miaA"
                     /locus_tag="IXR40_001796"
     CDS             16340..17257
                     /gene="miaA"
                     /locus_tag="IXR40_001796"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HAQ4361635.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            17259..18488
                     /gene="hflX"
                     /locus_tag="IXR40_001797"
     CDS             17259..18488
                     /gene="hflX"
                     /locus_tag="IXR40_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HAQ4361636.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
BASE COUNT         5981 a         3200 c         4022 g         5291 t
ORIGIN      
        1 atttgtctca cacccttttc cttcctactt gtaaccttgc tcccgtgtta gaaacatgtt
       61 acactaaata tgtgaaatta ttaacaagga gcgtcgttat gcgagaaaaa acagatacac
      121 tgccaaaagc aactgcgaaa agattacctt tatatttacg ctacttgaag atgctggatg
      181 actcaggtat aagtagaatc aaatcaaatg agttcagcga aatcacccaa attccttctg
      241 caacgatccg cagagacttc tcgcaattag gcgagctagg cagaagcgga tatggctatg
      301 atgtcccttt tcttatcgat gtattcaata atatccttaa tactaaagaa gaaaaacgaa
      361 tcgcattagt aggatatgga aatcttggca aagcattgaa acacaacaat tttagaagaa
      421 atgaaaatct aaatatcgtg tgcgtctttg ataatgatcc agcactgatc aatcgagtaa
      481 ttgatggaga aatgatctat ccgattgatc gtttcgcgga gatagccaaa gcaaaaaatg
      541 tgacagtagc aatctctacg gtaccaagta aatattcaca atctgctatt gatgaaattg
      601 tcaaaggaaa tgtaaccgct atacttaatt ttgcgcctga cagagtaact gtcccagctt
      661 atgtcaatgt tcaatacatt gatttgacaa ccgagttgca gacgcttatt tactttgatg
      721 agaattactc agaagttttt tcttaggaaa atttgagtag gcttattgat cttgcgagaa
      781 ctcgtcgtaa ttctttcaaa aattttttag tactaaatga agtggttttt tcacgaccac
      841 ttgttgacta aaaaaaaaaa ccattgtaga atgaagcata acgctgaaca agaggagtaa
      901 ctggcacatt cattcttaga gagagaacta tctgctgaaa ggttctcaat gacaaccagt
      961 gaaggtagct tgggagtttc tgtcttgaat ggagtagaga tagacgagtc gtgatcgtta
     1021 actcacttga gaggcaataa tgattgatta ttgcaattta ggtggtaccg cgtaaatcat
     1081 acgtcctaga atacgaaagt attttaggac gttttttagt ttaaaggagg aaaacagcat
     1141 gacggaagaa aataacctat caacaaaata taatccgcaa gaagttgaag ctggacgtta
     1201 tcagcattgg ttagaacaag atttgtttaa accgagcgga gataaaaaag caaaacctta
     1261 ttcaatcgta atcccgcccc caaatgttac tggaaaactt catttagggc atgcttggga
     1321 tacgaccttg caagatatgc tgattcgtca aaagagaatg caaggatatg atactttatg
     1381 gctgcctggt atggaccatg caggaatcgc gacacaagca aaagtagaag cgaagcttag
     1441 agagcaaggg atttctcgtt atgatctagg tcgtgaaaag ttcatcgatc aagtgtggga
     1501 atggaaagaa gagtatgcga gccacatccg cgaacagtgg gctaaaatgg gcttatcttt
     1561 agattacagt agggaacgtt ttacattaga tgatggatta tctgaagcag tacgtaaagt
     1621 ttttgttacc ttatacgaaa aaggtttgat ttatcgtggt gaatatatca tcaactggga
     1681 tcctcaagca cgaacagctc tatctgatat cgaagttatt cataaagata tcgaaggcgc
     1741 cttttatcat atgagctatg aactagcaga tggatcaggc gtagtagaaa ttgcgacaac
     1801 ccgtccagaa acgatgttgg gagatacggc gattgctgtt catccagaag acgagcgtta
     1861 tcaagcgctc atcggcaaaa aagtgattct acctttagtc aataaacaaa tcccaatcat
     1921 tgcagatgaa tatgtagata tggaattcgg gacaggtgta gtaaaaatca ctccagcaca
     1981 tgatccaaac gactttgagg taggtaatcg tcatgatctt ccacgcgtaa atgttatgga
     2041 tgatgatggt acgatgaatg aactagcagg aaaatatgct ggaatggaac gttttgctgc
     2101 tcgtaaagca atcgtgcaag atctgaaaga aatcggtcga ttgattaaaa tcgatacgat
     2161 gatccacagt gtgggtcatt ccgagcggac aggtgtcgtt gttgaacctc ggctgtctac
     2221 tcaatggttt gtaaaaatgg cgccgttagc gaaaaaagcc attgataacc aagaaacaga
     2281 tcaagcagtg gaattcttcc ctccaagatt caatcaaacg tttttacgtt ggatggaaaa
     2341 tgtccatgat tgggtaatct cacgacaatt atggtgggga catcaaattc ctgcatggta
     2401 tcacaaagaa acaggtgaaa tgtatgtagg gatggaagca ccagcggata gtgaaaactg
     2461 ggtacaagat cctgatgttt tagacacttg gtttagttca gctttgtggc ctttctcaac
     2521 aatgggctgg ccagatacgg aaagcgaaga ttataagcga tacttcccta ctagcacttt
     2581 agtaaccggt tatgacatca ttttcttctg ggtaagcaga atgattttcc aaagcttgga
     2641 atttactggc gaacgtccat ttgagaatgt cttgattcat ggattgattc gtgacgaaca
     2701 agggcggaag atgagtaaat cattaggtaa tggaatcgat ccgatggaag taatcgaaaa
     2761 gtatggagca gatgctctcc gctggttctt atcgaatggt tctgcaccag gacaagatgt
     2821 ccgcttcagc tatgaaaaaa tggatgcttc ttggaacttt atcaacaaaa tctggaatgc
     2881 ttcacgtttc gttatcatga atatcgaagg aatgaccgta gaagagatcg atttatctgg
     2941 agaaaaatca gtggctgacc ggtggatcct tactcgtttg aatgaaacga tcgaacgagt
     3001 aactgagcta tttgatcgtt ttgaatttgg tgaagcaggt cgacaactgt ataactttat
     3061 ctgggatgat ttttgtgact ggtacatcga aatgagtaaa gaagtacttt atggagatga
     3121 tgctgtttca aaacaaacca cccgtagcat cttagtccat acacttgatc agatcctacg
     3181 tttattgcat ccaatcatgc cattcgttac agaagaaata tgggaacata ttcctcatca
     3241 gggaaattct ctagtagtgg cagaatatcc tgttgtacgt ccagagtttg atgatgaaac
     3301 agcttctaaa gggatggaag tattgaaaga attgattcga gccgttcgaa atattcgttc
     3361 agaagtgaat acaccattgt ctaaaccaat tacgttgcta attaaaacaa acgatgctaa
     3421 aatcgatcaa tttttagttg aaaatacaag ctatatcgaa cgcttctgta atcccgaaga
     3481 gttgacgata tcaagtgaga tcactgcgcc agatctagcg atgtcagctg ttctgacagg
     3541 tgcagaaatc ttcttgccgt tagcaggatt gatcaatatt gaagaagaaa tcaaacgatt
     3601 agaaaaagaa ctggaaaagt ggacaagcga agtaaaacgt gtccaaggaa aactttctaa
     3661 tgaacgtttt gtttctaacg cgccggaaga agtagtagag gcagagcgtg caaaagaaaa
     3721 agattattta gagaagcaaa cggctgtcaa agaacgaatc gaaagtttgc gtactattca
     3781 ataagaatag aaaaagagag tgtgaaatca gctagctatt actaaaagct agctgattga
     3841 acatcgttac aggaaagagt ttgagcctca ctcttagctt cgattcataa ggagatgtga
     3901 cataaatttt gtcgcatctc ttttttagtc tactcttatt atgtaggaga aggagggagg
     3961 tggatcatgt atcaagagtc aataaagtag ttgataaaat cgttcctctc tctgtttctt
     4021 ttctctttgt catactttta tttttcttat gtgttctatt tgttataata aaagagaaat
     4081 gggggaattg ttgatgacga ttgaagaagc aatagaatgg atccatagtc gattaccatt
     4141 tggttcacgt cctggccttg accgagtcga agctttatta gaagtggtag ggcatccaga
     4201 gagaaaagta aaaacgatcc atatcgctgg aacaaacgga aaaggttcta ctgtagctta
     4261 tttgagaagc ctattagaag aggctgggct gacagtaggt acatttactt caccttatat
     4321 cgaaacgttc aatgaacgga tcgcaatcaa tggcaaaagc attccagaca atgatttgat
     4381 ccagcttgta aaaaaatatc agccactgat caaacaactt gatcaatttg aagcagtagc
     4441 tggtattact gaattcgaga cattaacagc aatggcattt gattattttt tgatgaagaa
     4501 agtggacgta gcgattatcg aagttggctt aggcggctta ttggattcta ccaatgtagc
     4561 tgtaccaatg ctgacgggaa taacaacgat tggacttgat cataccgaaa tacttggaga
     4621 tacaattgaa gaaatcgctg cacaaaaagc tggaatcatc aaacaaggcg ttccagtagt
     4681 aacaggaaat attgccccag aagcttttac tgtcatccaa caaacagcta aagcaaaaaa
     4741 tgcaccgctt tatgtatacg gggaaaatta taaaataaac tatctgcatc ctgatgagat
     4801 gtggggagaa gtatttgaat tttttaatga aataggaaag atccctcaat taaccactcc
     4861 gcttttaggg caacatcaag ctgaaaatgc aggagtagcc atcgaattgt attttgttta
     4921 ctgtcaattg gaaaagctgc ctttccgaga aaaagatgtt ttgaagggat tgaagaaatc
     4981 tcgatggcca ggaagaatgg agcgtttgag taacgagcca ttagttgttt tagatggtgc
     5041 ccataatacg catgcaatga accggcttgt tgagaatttg aaaaaagaat tcaaaggata
     5101 tcaaatcaac attttgtttt ccgccttacg aactaaaaat gttagagaaa tgctagaacg
     5161 attgcagcaa gtaccaaatg tccatattta tttgacgacc tttgaacatc caaaagccat
     5221 cgaattaagt gaagtatcag atttagcaag tgagagagta tcaatcgttt cattgtggca
     5281 attcggatta gcagatatat tggaaaagat gacaaatgaa gacgtattag ttgtgaccgg
     5341 ttcactttat ttcatttcag aagttcgcca tttattaata caattaggag gagatcatga
     5401 agtataatgc agtgattttt gacatggatg gtttgctgtt cgacacagag ttagtgtatt
     5461 acgaagccac acaagtagta gcagacaaga tgggttttcc ttatgataaa gacctgtatt
     5521 taaaattctt aggtgtttca gatgaagaag tatgggcgaa ttatcatatg attttctcgg
     5581 aatttggcaa aacaagtgta caaagattca tagatgattc ataccaggaa acgcttgaac
     5641 gtttttcgca aggagcggta caaatgaagc ccggtgtgtt ggaactcctc tcttttttag
     5701 aagaacatca gattcccaaa gttgtcgctt ccagtaacca acgagcagtc attgaacttt
     5761 tattgaagaa gaacaatctg tttgaacgat ttgagacgat tgtttctgca gaaaatgttc
     5821 aacgagcaaa accagaccca gaaattttct tgttagctaa tcagaagcta ggtacagcga
     5881 agaaagaaac attgatttta gaagattcac aaaatggtat tttagcagct tctgcggctg
     5941 agatcccggt agtcatggta ccagatctgc ttccaccatc ccaagaattg atcaaaaaaa
     6001 cagctggggt tgtttcttct ttacatgaaa tccctgcatt gttaaaataa aaatccatct
     6061 cttttcgtat cttattttag ataagataga aaggagatgt ttttttggga aaacgattga
     6121 tcaaagaagt acctactagc tctttaccaa gggaacgtat ggaaatttat ggcgcggaag
     6181 ctttatcgga tcaggagctt ttggcaatct tactgcgtac cggtcaacac ccttatagtg
     6241 tgatgtcgat tgctggaaat ctgttaaaaa cgtttggagg actggcctct ttacgacagg
     6301 ctactttgca tgagttagaa gagattcgag ggataggacg cgtgaaagca atcgaaatca
     6361 aagccttgat cgaattaggt cgacgaattc agacggatca tgaaagagcg gctccaccgg
     6421 ttcgtaccag ctacgaattg gcccagcaat tgattctgga aatgaaagat cacaaacaag
     6481 aacatttggt ttgtatttat ttggacacga agaatcaagt gatcttaaaa aaaacagtgt
     6541 tcatcggttc gctgaatcag tcagtcgctc atcctagaga aattttccat tatgctgtac
     6601 gttattgtgc agcaaggatc gttttagcgc ataatcatcc ttctggtaat gttattccat
     6661 cgcagcagga tatgaatttt accaaaagga tacaaaagtg tggagaaatg atggggatca
     6721 ctgtactgga ccacttgatc atcggacgca aacgatattt tagtttgaga gaagaaggaa
     6781 tgatggaaga gaagtaagtt gctttcttgc aaaaaaaatg aagcaagtgt acaattatat
     6841 tgtaattttg tttgggaata gaagttgaaa catctgttgc acctctatcg tacacgagca
     6901 atgttacaat ttaaattagt gcttttggca cgaggaggat attattatgg aaaacggaac
     6961 agtaaaatgg ttcaacgctg aaaaaggatt tggatttatc tcacgtgaag atggaagcga
     7021 cgtattcgtt cacttctcag ctatccaagg tgacggattc aaaacattag aagaaggtca
     7081 agcagtgact ttcgacgttg aagaatcaga ccgcggccca caagctgcaa acgttgtaaa
     7141 agcttaattt tatctgtaaa tcaaattgat ggtagacatc aatttttacg agagaacaaa
     7201 gcgagtaaca aaaatacctg ccacaagaga caatttctct tgtggcaggt atttttttgt
     7261 atgaaaaagt aaataaattt aagaggctat gaaagagcca ccttgtatca aggaataaga
     7321 acaaacaaaa atggcttctc atgtttttca tttgttttct cttatattca ggacaaggtg
     7381 ctgatttcat aacctcttat ttattcttca tctggtgtca ttaccattgg caaaatcatt
     7441 ggatgtcttt ctgtacgttc gaataagaaa ggctgaagcg cgccagtcat cgcttctttc
     7501 aatttatatt ctgaacagtc aggtccattc aaacattctc ttaaagcgtg gaataagatt
     7561 cgctgagctt cattgatcat ttctcctgat tctcgcatgt agacaaatcc acgagagaga
     7621 atatctggac cagccaagat ttcttttttc ttgatatcca ctgtcgcgac agctaataca
     7681 agaccttctt ctgaaagcag gtgacggtca cgtaaaacga cattaccaat atcaccgatc
     7741 ccgctaccat cgatatacac atctccagcc acaaaatgcc cagcaggacg cgcagaatcg
     7801 ctagttaacg ctaaaacatc gccattttcc atgatgaagc agttttctgc aggaacacct
     7861 acatcttgtg ctagagaagc atgtactttc aacatgcgga attctccgtg gacaggaata
     7921 aaatattttg gcttcatcaa acgaagcatt aatttttgtt cttcttgtcc accgtgaccg
     7981 gaagtatgga tgttattgat ttttccgtga atcacttctg caccagcttc agacagcaaa
     8041 ttgatcaaat gattgacact tgttgtatta ccaggaatag gtgaacttga aaagatcact
     8101 gtatcgtctg gctggatttg gatttgacgg tgagtaccat tcgcgatgcg gctcaacgcg
     8161 gccatcgctt ctccttgaga acctgtacat aggatcatcg tttcattggc aggcaagcga
     8221 ttgatttcgt gtgcatctac aaatgtgccg tctggaactt tgatatatcc taaacgttga
     8281 ccgttgacga tggcattttc catgcttcgt ccgaaaacag cgattttacg accagttgcc
     8341 acagcggcat ctgctgcttg ctgcaaacgg aagatgttag aagcaaagct ggcaaaaatg
     8401 atacgtcctt cgatttttga aaagatcttc aaaatagaat gcccaatcgt tttttctgat
     8461 ttagtaaatg ttggaatctc agcatttgta ctatcagata aaaggcacaa gactccttct
     8521 tccccgatac gagccatttt atgcaagttt gctggttcgc caacaggagt gaaatcgaat
     8581 ttgaagtctc cagtcgctac gatatttcca gaaggtgttt tcaccacgat ccctaatgca
     8641 tctgggatac tatgggtcgt tctgaaaaag ctgacagaag tctttctaaa acggatgatc
     8701 gtatcttcat tgatctcatg gagctctgca tctcgaagca agccatgctc atctaatttg
     8761 tttgtgatca acgctaatgc gagaggacca gcatagatag gaatatttgc ttgtttcagc
     8821 aagtagggta ttccgccgat gtggtcttcg tgcccgtgag taatcaccaa ggcttttact
     8881 ttgtgtaagt tttgtatgat gtagctgtag tcgggaatga catagtcaat tccaagtaaa
     8941 tcgtcttccg ggaatttgat cccggcatca atcaaaatga tttcatcttg gaattgtacc
     9001 ccatacgtat ttttcccgat ttcacctaat ccaccaatag caaagacgcc tgtctcgtta
     9061 tttttgatgg aaagtttcat attaaaactc cactaatgag aaatcagcat tttctttttc
     9121 gtactctaga tgacttcctt ctagaagttg aacgaattca atattgtatg gggtattttc
     9181 ttccacacgt tggcgagcgt ctacatcgct ttttgcctca atgtaaagag attttgtttc
     9241 ttcccgttta gggttgcgta cttttgtttc ttgataataa actttataga tcattgtttt
     9301 gtctccttta tctgcgtaaa gcagtgattt agctagttga tttttttaga caacacaaaa
     9361 cgaggggaca agccacctgg tttttcatat gctttgacta gaatactgga ttcgagtcaa
     9421 agagacaagc ctcgtttttg cttatctgtt cggatatttt ttcaaccgta ccttctgtat
     9481 aaaaaatata caacaattaa ttgttattct agcataaaac agcaaataag tatagaaatc
     9541 aactagattg aaagaaaaaa tcaatgttta tcatcccgct ataatcataa tgactttttt
     9601 atgagagaag tgttctatta ataggctcgt tgtgctatca tttttagtaa tgaaaatgta
     9661 acaaaagatt aaaaggagat gagaaagtga aactaatgtg gcattatacc atgcgttata
     9721 agaaattctt gtttttcaat ttcatatgcg tatttggttt tattttgatt gaattaggac
     9781 ttcctacgat tttagcacgt atgatcgatg taggaatccg caatgatgat tttgattatg
     9841 tgaagcaaca agggatattt atgatcgtta ttactgtaat cggtattatt ttgaatatct
     9901 tgttaggtta ttttggttcg aggattacga ctaatatcgt agcagatatt cgagatgatt
     9961 tgttcgaaaa gatccaaagt tattcgcatc aggaatacga aaatctaggc gtatcttcat
    10021 tgatcactcg tacaacaaac gatgcttatc agatcatgtt gttcctgcaa aatattttac
    10081 gtatcggttt tatggcacca atgatgttca ttgtcagttt gtacatggtc atgcgtacaa
    10141 gtgtgacact cagtttgtat gtagtaggtg cattaccttt actattattg gcagtcgtag
    10201 cgattgctaa ggtgtctgaa ccgttatcta aaaagcaaca aaaaaactta gataaaatca
    10261 acagtatctt gcgggaaaat ctttcaggat tgcgtgtgat tcgtgcattc gtcaatgaaa
    10321 agtttgaaga aaaacgtttt gctgtagtca atgagaatta tgcttctagt tcaaaaagct
    10381 tattccgttt gatggctgtt gcacaaccgg gtttttattt cttatttaat atcgtaatgg
    10441 tattgatcat ctggagcggg gcagtgcaaa tcgatgcagg cgagcttcgt gtaggagatt
    10501 tgattgcgtt tatcgagtat atattccatg ccttgttctc attcatgtta tttgctagtg
    10561 tgttcatgat gtatccaaga gcagctgttt cagctggacg tatccaagaa gccctagatg
    10621 ccaaaccttc gattgtagaa gatccaaatg gtatatctga tacaaaaact aaagggtata
    10681 tcgaatttca aaatgtaaca tttgcttatc caggccattc gcaagagcca gtgatacgaa
    10741 atgtcagttt tacagcctct ccaggagaga ccgttgcttt tattggaagt accggtagcg
    10801 gaaaatctac gttgatccaa ttgatccctc gcttttatga tgtgagtgaa ggaaagatct
    10861 tgatcgatgg agtagacgtg agagattatc ggctaagcaa gttgcgagat aagattgggt
    10921 ttattccgca aaaagcgctg ctatttactg gaacgattgc agataatttg cgatacggga
    10981 aagaagatgc tacgcaagaa gaaatggaac gtgcagctga gattgctcaa gcttcagaat
    11041 tcatttctcg aaaaccagat ggatttaatg aacatttatc agaaggtggt tccaattttt
    11101 caggtggaca aaaacaacga ttggcaatag ccagagccat catacgccgt ccggaaatct
    11161 atatttttga tgacagcttt tctgcattag attatcaaac ggatgcgaag ttacgtgctc
    11221 gtctgaaaaa agaaacgaca gaatctactg tattgatcgt agcacaacgt gtgggaacga
    11281 tcatgcatgc agataagatc atcgtattaa atgaaggaga agtcgtcggt atggggacgc
    11341 atcgggagtt gttggaaaaa tgcccgattt attatgatat tgccgcttct caattatcaa
    11401 aggaggaatt agcatgaaaa aaaccttttc ttccttaaaa cgtttagctc gatatatcag
    11461 accgtatcgt gagacttttc ttttagtgat cctatttaca gttctgacag tggctttcaa
    11521 cgtggctttg ccatatgtta caggacttcc tactacagaa atcagccgta atattgccaa
    11581 tggcgaatca atcaattttt cttatatatt caaatgtctc atttggatca cagttgttgg
    11641 aatagggtat tgtatttcgc aattactttc tggtgttttg atgacaaatg tcgttcaaag
    11701 tgccatgcat gatttgagaa gagacataga agaaaaaatc aatcgtcttc cggtttcata
    11761 tttcgataaa aaccagcaag gaaatatttt gtctcgtgtg acgaatgatg tagatgcagt
    11821 cagcggtgct ttacaacaag cttttattgg tatcgtaaat gcgatattgg gaattacgtt
    11881 ggctgcagca atgatgtttt atatccagcc gatgatggcg ctgatctcta tgatcatgat
    11941 tccaacatcg atctggatct caaaacgagt gatcaatgct tcgcagaaat attttcaaag
    12001 catgcagaat tctcttggtg agctaaacgg ctacgtccaa gaaaatatga caggttttag
    12061 tgtattgaaa gtatatggac gcgaaaaaga aacattggaa ggattcaaaa aagttaatca
    12121 cagcttgaaa tactttgggt ttcgtgcagc attcatttct ggcttgatga tgcctctagt
    12181 tcaattaact gcctatgcta cttatattgg tatggctgtt ctaggaagct tttatgttat
    12241 tactggggcg atcgttgtcg gtcaactaca agcattcatc caatatattt ggcaaatcag
    12301 tcagccaatg gggaacgtga cacaattgtc ttcagttttg caaagtgcat cagcggcaac
    12361 gaaacgtgta ttcgagattt tagatgagcc agaagaaaaa gaaaacaaag tagatgcttc
    12421 actgccagaa acgattttag gagatgtgac attcgatcat gtcgattttg catatgatcc
    12481 gaagaaacca ttaatccaag atttgaattt tgaagtgaaa gctggtcaaa ccgtagctgt
    12541 ggtcggtccg accggtgccg gcaagacgac attgatcaat ctattgatgc gtttttatga
    12601 cgtagacaaa ggagcaataa ggattgatgg aatcgacacc aaatcaatga gtcgcagtga
    12661 tgtgcgttcg ctatttggta tggtcttgca agatgcatgg ctttatcaag gaacgattgc
    12721 agataatatc cgcttcggaa agcttgatgc gacagattat gaagtagttg atgctgcgaa
    12781 aacagcaaac gtagatcatt ttatccgaac gatgccagat ggatatgata tggccatcaa
    12841 ttctgaggga gacaatgtgt ctttaggaca aaaacagttg ctgacgattg cccgagcagt
    12901 ggtctccgat cctaaaatct tgattttaga tgaagcaaca agttcagtag acacccgttt
    12961 agaagcgttg attcaaaaag caatggatcg cgtgatggag ggacggacaa gtttcgtcat
    13021 cgctcaccgt ttatcgacaa tccgtgatgc agatctgatt ctagtgatgg atcaaggtca
    13081 gatcattgaa aaaggaacgc atgagagttt attggcacaa ggtggatttt atgaaaaact
    13141 gtataacagc caatttgctg aggaagcaga ataagtcata taagaataaa acagtttaaa
    13201 acttattttt tgttctctat tcttgataat ggtaaagtaa agttatcaag aaaagtgagg
    13261 acacggagat ggaacagttt ttaaatgaaa aaattactga agccaaaaga gaagttgatc
    13321 gtttaacgca cgtctgtcag acgaagcctt ttgattcagc tgattttttt gaaaatgagt
    13381 ttcaaatcga acgcttggca gcacaaatag aagtgtacga attaatttta aaaaaagtaa
    13441 tagaagaaaa tatagatgta caataaaaac aggtaaaacg tcagttacca gatactgtaa
    13501 atagacatct ggcctgagca ggttttacct gttttttttc ttatgaaata aatatatgct
    13561 atgatacctt tattcaatag gattagtttc tacaaaaaat gaaaggagaa aaataaatat
    13621 ggaacggttt atagcatcaa atgccacagt gattggtgat gtgacattgt cagaagatgt
    13681 gacgatctgg tatcaagctg ttttacgcgg ggacagtaat tggataaaaa taggacaaag
    13741 aacgaatatc caagatggta caatcatcca tgtcgatcat gatgcacctg tagatattgc
    13801 ggagaatgtg acggtaggac atcagtgcat gctacatggc tgtacaatcg aaaaaggggc
    13861 gctgatcggg atggggacca cgatattgaa tcatgcggtt attggtgaga atagtttgat
    13921 tggtgctgga tcattagtaa cagaaggaaa agttattcct cctaatgtct tggcttttgg
    13981 tcgcccagct aaagtgatcc gtcctttgac aaaagaagaa atacaaaaaa acaaagaaaa
    14041 catccagcat tatgtcgaga taggtcggat gcatgcgcaa ggaaaattca aggagcaaag
    14101 ataggcagta gcatccataa aataaaaaag gatggtcagt ttgagttgac catccttttt
    14161 tatttggttt agataagaga gcttaaaaaa gcttcctttg aaacagatta atttaatgaa
    14221 gaactgtttt ccatgacttc atcgatcaat ccatatgctt ttgcttgttc agctgtcata
    14281 tagttgtcac gatctgtatc tttttcaatc acttcaagcg gttgtccagt gcgttcagct
    14341 aaaattttgt ttaagcgttc gcgtgtttgc aaaatatggc gtgccgcaat ttcgatttca
    14401 gttgcttgcc cttgagcgcc gccaagaggt tgatggatca tgatctcagc atttggtaaa
    14461 gcaaatcgtt taccttttgt accagctgtc agcaagaagc ttcccattga agcagccata
    14521 cccataacaa ttgtttggac atctgctttg acaaagttca ttgtgtcgta aatagccata
    14581 cctgctgtaa ctgaaccacc aggagaattg atataaagat agatatcttt ttcagaatct
    14641 tgagcgtcta agaaaagcaa ttgggcgatg atcgaattag caagatcatc tgttacttgg
    14701 ccgcttaaca tgatgatacg gtctttcaat aaacgtgagt agatatcgta agctctttca
    14761 cctcgtgaag attgttcaat gactgtagga attaaattca taatagagtt cctccttgat
    14821 ttcgtttaga aatagtgtac cataatttag tttctaatac ctaaaatgta gtatacattt
    14881 ttggtcaaaa aaggtcaaat aaaaaactta ggcaaattag tcgcataaac ccgctttatg
    14941 gtatgataag cagagaaaca aaacaaggag gaacaacaga ttgatagttg gtattactgg
    15001 ccttatcgga gtgctgacag gtgctgtagt tgtctatatc ggcatgatac tgcaaatgcg
    15061 tcacttggaa aataaagaac agcgtagacg tgaattggaa ttgaaagtca aagaaatcga
    15121 gacgctgaat caattaaata aaaagatcaa cgagatcttg caaaaacgga caacgctgat
    15181 ggaagaatat gtcagctttg atgcatttga tgattgttat atcacgattg acgattttgc
    15241 gtatctccaa tcattttcag cgcaaaatag tttttatctg ccaaattata ttttagacga
    15301 gctatttaag aatatctccc atcgaaaagt gattttatct ccagatgaaa caatgaagat
    15361 tggtggatat gcttataaag gcggacgcgt gattttagag aattttacgg atagtctgac
    15421 tgaaatgatc aatgaaaaaa aagctcagtt gaagactatg acgcgccagc cgattggttt
    15481 cttctcgaaa gatgatgttt ggagctgata ttttgaagca ttgccgttgc acatgagagc
    15541 gtggtaatgc tttctttttt tcttaatgat acaatagaac tgaacggagt gaagaaagat
    15601 gttacaaatc tatgcccatc gcggaagcag cggcacccac ccagaaaata cgcttcctgc
    15661 atttgcagaa gctgtacgag taggtgcaga tggtatcgaa ctagatgtcc atctaagcaa
    15721 agatggttat ttgatcgtta tgcacgacga agaagtggac cggacgacta acggtaaagg
    15781 gctgattcga gaaaaaacat tggaagaact caaaaaattg aatgcagggg gcaaattcag
    15841 caaagaattt ccagcagcta aagttcctga attgagagaa gtgttaggac tgctcctcca
    15901 aaaaaattac cgagggatgc taatgattga aattaaaact gatcagtatg aatatcccgg
    15961 tatcgaagaa aaattagccg aaacattaaa aagtagagat tggccttttc aacatgcata
    16021 ttgcagcttt catttggatt ctttggaaaa aatcgcatta ctggaaccgg agatacagct
    16081 ggacttattg atgagtactt ctgataaaaa gatccaacta gcagcagaaa ccccttatat
    16141 agaaggagta catccaaaaa atacttggtt gttcgaacat ccagtccagg cagctgattt
    16201 tccaaaagca attcgtgcat ggacgattaa cgatgaagaa gaaatggcca aatgtcaaga
    16261 actcaaaata gatggaataa taactgattt tccggagaaa gctcttcggt ggaaacaatc
    16321 aacgaaaagt aggtaaaata tggaaaaagt attagtgatc gtcggtccga cagcagtcgg
    16381 taaaacagcg ctaagtgtgg aactcgcaca actatttgga ggagagatca tcagtggtga
    16441 ttcattgcaa atctataaaa atctggatat cggtacagca aaaatcaaag aagaagagat
    16501 gaataatgtt ccgcatcatt tgattgatgt gatcgaacct actcaacgtt actcagccgc
    16561 tgattttcag cattcaggtc gacaattgat taccgagatt gcgaaccgag ggcacctacc
    16621 tatcatagct ggtggtacgg gtctctatat ccaatccctt ctatatgatt atcagttagg
    16681 agcgacagaa gaagcgaatc ctgagattag aaaaaagtat gaaacgttag ctgaaacaat
    16741 tggttcccaa gcattatgga atcagttgaa agaaaaagac ccggcagctg ctgagaaaat
    16801 ccactggaac aatcaacgca aagtgataag agctctggaa gttttagaga cgacaggaca
    16861 tagtatcacg gcacctaaag aagagccaaa gcaattgtat gattacctca tgattggatt
    16921 agatacgaag cgtagtattc tttatgaacg aatcaatcaa agagtcgatt tgatgctagc
    16981 agaaggttta gtagcagaag cgcgtaaggt gtatgagctt ggagaagtcc aggccagtca
    17041 aggtattgga tataaagaat ttttccctta ttttgaaggg aaagaaacat tggaagaagc
    17101 aacagaacaa gtcaaactac attcgagaag atacgcgaaa cgtcagttga cgtggtttcg
    17161 taaccgtttg gatgcacagt ggtttgatct tataagtgag ccaaatcaaa aaagtcagat
    17221 tgagcaaaca atcaaaaaat ggctggaggc ggaataaaat ggaagaaaaa gtgatcatcg
    17281 taggggtaga aaccgaagca aaccagcgtt acttttcaga gtcaatggaa gagctagttc
    17341 agctgacgaa taccgcatca ggagaagtcg tattcacaat tacacaaaag agaccacaag
    17401 tggatcggca aacgattatc ggtaaaggga aattacaaga attagttcaa caagcggatg
    17461 cgcatgaagc ggatttgatc atctttaatc atgagctaac tccgagacag agccaactga
    17521 ttaccgatgc tgttggtctt ccggtaattg atcgcgtgca gcttatctta gatatttttg
    17581 cgatgcgtgc tcgttcgaaa gaagggaagc tgcaggttga acttgctcag ttagaatacc
    17641 tgctgcctcg tttagtaggg caagggaaaa cattatctcg tcttggcggt gggatcggaa
    17701 caagagggcc aggtgaaaca aagttagaaa cagaccgccg acatatacgg aataaaattt
    17761 ttgctgttaa gaaagaattg aaagaagtag aagctcatcg agagcgcaat cgccaaaaaa
    17821 gaaaaaatag cgagattttt cagattggac ttattggcta cacgaatgcc gggaagtcaa
    17881 ctatcttgaa tctattgaca caagcggata cttattcgaa agatcaattg tttgcaacgt
    17941 tagatccatt gactaagaga tggcgttttg ctgaaggatt tgagattact gtaacggata
    18001 ccgtcgggtt catccaagac ctgcctacgc aactgatcga tgctttccat tctacattag
    18061 aagaaagtca aaatatggat cttttgctac atgtagtcga tgctagttct ccagatcgta
    18121 ttttacagga gcagactgtc ttaaaattga tggatgaact gaatatgaaa gaaatgccga
    18181 tactgactgt ttacaataag gcagaccaga tcgacccagc gatgttcacg cctacgctat
    18241 tcccaaatgt attgatttct actcagacga aagaaggtaa gatggcgttg atcgaagcaa
    18301 tcaaacgtca gctgatggaa ctaatgaccc cttatacact ttctgtgcca agcaacgaag
    18361 gacagaaatt aagcgagttg agaagacaaa caatggtttt ggacgaagcg tacatggaag
    18421 aaacaaacga atatgaagtt aaagggtttg caaaaaccaa ttcaaaatgg ttaagaaaaa
    18481 accaataaaa tttt
//
LOCUS       DACGEU010000055        18088 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.055, whole genome shotgun sequence.
ACCESSION   DACGEU010000055 DACGEU010000000
VERSION     DACGEU010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18088)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18088)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18088
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.055"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            320..736
                     /locus_tag="IXR40_001798"
     CDS             320..736
                     /locus_tag="IXR40_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HAQ4361637.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIEAERDAILAALMALSLISRQILYYSFCDVNKHSNYEI
                     GQLIRGYGEKNVEKLKSIALIEFAEAYKKGVLIQYR"
     gene            1645..1989
                     /locus_tag="IXR40_001799"
     CDS             1645..1989
                     /locus_tag="IXR40_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HAQ4361638.1"
                     /translation="MTEEFYRWLLQLIREDRLVKFYQSSKWRRLREKAMKRDHYECQE
                     CRRLGKYHRVENVHHIKEVKDRPDLALDLDNLICLCVEHHNEVHGRYLTALDKQEKKI
                     ESFANFDASERW"
     gene            1994..2275
                     /locus_tag="IXR40_001800"
     CDS             1994..2275
                     /locus_tag="IXR40_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361639.1"
                     /translation="MIINDNGREYDTEKIEEYSSYTQGLIKRLIYVRYVGIRDLLSDN
                     CCSKYKVNQVREALNKDNNVERIKNVFGYSIEEINYYIDFAEAFIPMVR"
     gene            2378..2692
                     /locus_tag="IXR40_001801"
     CDS             2378..2692
                     /locus_tag="IXR40_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HAQ4361640.1"
                     /translation="MFKNELSQNRYREKLRRSLISQLESQKTNIEPFLDNVDRYISLW
                     ETAISLEEDISENGIRLENGKKNESVALLVSVNKQMGLMLDKLAITPELVGEANESIP
                     EL"
     gene            2670..4364
                     /locus_tag="IXR40_001802"
     CDS             2670..4364
                     /locus_tag="IXR40_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HAQ4361641.1"
                     /translation="MNQFLSYKHIENWFKAIEEGTIKVCKEQLLLKNYLEERVFTRED
                     IYFDKQMVEDSINIPAQYFPFELIPWEKFLQCFIYGVRWKKDKTLVFNRYLSLMGRGN
                     GKTGFASWNNFFLLTAKHGIKNYDIDIYANNESQAKTSFDDVFKVIKDHPDLDKKVFK
                     ATKEVIQNIATNSKLRYNTANARTKDGKRPGANRFDEIHENEDYSMINVATSGGGKIR
                     DYREFYDTTNGHVRGGPLDDIIEESKMILSGELGIDKDGAEFSSLFPFICRLDNDNEV
                     DDPDMWEKACPTINYNADLKRKMFQEYSQMQRNAGLRLTFMTKRMNRPMEDTRFAVAS
                     YDDVLHTKEKEFPEKMDEVIGTVDFADRRDFASVGLLGKYDKDVYFTQHTFIHESALR
                     LQNIKREVIDISIDQGKSQIVHGKNIEADYIVGWFLEMSNKYYIKKIAMDMYRAKILK
                     PALEEAGFTVEIVRSGSVTHGMLKDLVDDLFINQRLFFGDDAIMRWYCMNVYEEHISN
                     GNIRYEKIEPETRKTDGFFSFLHGLNFLDDIYDSAPVTVTNSSVENTGTGFTPLVF"
     gene            4384..5562
                     /locus_tag="IXR40_001803"
     CDS             4384..5562
                     /locus_tag="IXR40_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HAQ4361642.1"
                     /translation="MGIFQKAVGYFTKKATVPLEEYFCKLQVDFVYRKFAIETCIDLI
                     ANAMSKAEFKSYEDGKNKKNDLYYRLNVAPNKKNNATEFRKKLIRRLIFYNEVLIVSP
                     SNNSSEIFIADSWDVTEYALKDDVFSQVQINNIVLDREFLESDVIYIKYADQQIRQLV
                     DAYYQAYGKLISSAMNVYKRSNARRYVLKGNLFRPQDNTTQDQINKMMTSQFKAFMEA
                     DNAGAVFQLQNEYTLEDFSGNFQSNSRDIKNLIDDIFEMTAAAFHVPKNLLKGDMSGL
                     SDQVDAFLMFEIIPIAELIQDAFNASLYEVEEYLSGNFVRVDTTMIKITSFKDLVDAI
                     DVGIRNGVFTINEGRERVGNDRSDKAMADEIFITKNNQQVSKGGEANDDNENISSSKE
                     "
     gene            5525..6211
                     /locus_tag="IXR40_001804"
     CDS             5525..6211
                     /locus_tag="IXR40_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HAQ4361643.1"
                     /translation="MTTMKTFLAVKNEGAVPQIFIQGFIGSSWFFEGNTDKGIKNILD
                     SLGDQEEIEVVINSNGGDVFQGIAIGNLLKSNKAKVNVVINGLAASAASIIAMAGDTI
                     KIYNNAQLMIHRASTYGEGNVDDFRTIADQLESIDKSVKASYKTRFNGTDEALQELLE
                     KESFMDAETALSYGLVDEIIDAENSSGTEAKKEQSVEEILNDVKEKRAEKIAAFTAAL
                     NKTFGQGDVK"
     gene            6211..7371
                     /locus_tag="IXR40_001805"
     CDS             6211..7371
                     /locus_tag="IXR40_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HAQ4361644.1"
                     /translation="MTVKNLKGVTAASDQLMKAFKDGNEESFSAAMVSLSKEIQDKIL
                     EEATAKNQDQLVLMNRGQRVLTTQETKFYNEVVKNEGFAGVEELVPATVFERVFEDLE
                     QSHPLLQKITFVNTTGVTEWIVSRGVNPAWWGKLCEAVKKVLDNDFDVINMKQFKLSG
                     YIPVCKAMLDLGPVWLDRYVRTVLVESLRIALEQAIVDGTGKDMPVGMMRDMSKQTSG
                     EYAEKKAEPITALDAVTMGGLMARLSKFNIEGVNDPIYRNVNPSDVVLIVNPTDYWSK
                     VFPAKTVLTANGEYVQVLPVPVSDLQSTAVPEGKAVIGVASDYFMGVGSTLKIEASDE
                     YHFVEDERIYLAKQYANGQPKRNDSFIVLDISALGTTTTTTKPTTTTTTTQA"
     gene            7381..8256
                     /locus_tag="IXR40_001806"
     CDS             7381..8256
                     /locus_tag="IXR40_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361645.1"
                     /translation="MKYILCQPAINRFKWELEVCLTNLKKLGIKDIVLLFSRHDDQIP
                     IFFEKEYGVEVHVYDDLRDDKEYIPSIKPYLWWKYLEEDHSREDDRYFYIDSDVIFNK
                     RINLRKLPSKDDVWYCSDCCSYLSLDYIRSCENGENILKDMANIVNVTVESLETINTN
                     SGGAQWVINRPKANYWKKVYLDSNRLYRYLRGQKTNIQIWTAEMWPQLWNMMYFNIGP
                     KVHEELDFCFATDPIEKVKEVKILHNAGVTTNDEDLFFKGRYVTSTPFDEDLSFVNKK
                     KCSYAYVKAIKAVVR"
     gene            8253..8564
                     /locus_tag="IXR40_001807"
     CDS             8253..8564
                     /locus_tag="IXR40_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361646.1"
                     /translation="MTPEQVTEELLIAVKDNIYVTWNEEDESIKKMIAKNAVYLQSKV
                     STTLSFSPESLEYGLLIERCRYDWNRALDEFEQNFASELLGFIQHYALQEYIAGDVNG
                     E"
     gene            8554..8907
                     /locus_tag="IXR40_001808"
     CDS             8554..8907
                     /locus_tag="IXR40_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HAQ4361647.1"
                     /translation="MANNRRLEETFNDGWLKILTQTTKRNELGKKIGVEDTEITSLKF
                     RNLSMRDSDITAMDAMGSKLTKKVKTPFHPIAKKFNKDQYFIVIDSMRYNVIYADYDN
                     FYIYFYLESVGEYGD"
     gene            8897..9298
                     /locus_tag="IXR40_001809"
     CDS             8897..9298
                     /locus_tag="IXR40_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361648.1"
                     /translation="MVIDNSKEKERLNKQISAIKTSLEEHFGLKLFQDSVGEDELPDD
                     FNYFILETGEIEMITEPKYSVGQNLYLTFYSENREDLTGDSLDIISLIQNRSIRFQRM
                     DPNHLKLENQDRYIDQLVFTFRRLLKSDCHG"
     gene            9291..9695
                     /locus_tag="IXR40_001810"
     CDS             9291..9695
                     /locus_tag="IXR40_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361649.1"
                     /translation="MAKNSWELKINGHDELLVRMERYSSESERLINEALKSKGSAIAV
                     DRITEKIPVSEADLRRGHQHAKNSRPLKTQYINLGFIIRPTRKFEYLKYPDLGIGTSK
                     RNQPDEFMRRGLGLALDPITELLIRQFDKLNK"
     gene            9707..10312
                     /locus_tag="IXR40_001811"
     CDS             9707..10312
                     /locus_tag="IXR40_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAQ4361650.1"
                     /translation="MAKTTTVTTFDNISIKRISFNFKNATNAISTDCNGQLDGETEMQ
                     RIVKKCGSTEVKSKSKPINMTVTITAHVPMEVYRRFNGLKQDERIKSGIYSYGPDSVG
                     EDFSLAAEIVDDFEEKNKLIGMLACTSNTGLTFSIENGADEVAALELETKVMQDEFGK
                     FYHEAIVAELEEDLTDQWMTNLSADVIKKTSVVTTTATQSQ"
     gene            10332..10694
                     /locus_tag="IXR40_001812"
     CDS             10332..10694
                     /locus_tag="IXR40_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361651.1"
                     /translation="MNEDYSKIELNDGTILNLEPKLNIKKLLMINRDFNTDEFAKMSM
                     GKGSMDITVIQGAKAVYVAYRQANMVDYISFDEFIDKWDFDMEVAVAVYSTMMFKQAR
                     DAYQKEFEKANKEKKLQK"
     gene            10697..10879
                     /locus_tag="IXR40_001813"
     CDS             10697..10879
                     /locus_tag="IXR40_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361652.1"
                     /translation="MPKLLVETWVDVYSMLTDVFSMPSDLVLSDICLDDILQMAYNKS
                     AYEGWKNYAINQSQKN"
     gene            10897..14217
                     /locus_tag="IXR40_001814"
     CDS             10897..14217
                     /locus_tag="IXR40_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAQ4361653.1"
                     /translation="MAKKRTEAEVTFIANDDGLKSTLKEISAELTKNRAELKLEQAQL
                     QQTGSESDKLGSKLSSLEKQYELQSQKVEVTSQRLANAKKYYGENSTEVQKLERELIN
                     QQTAQQRLSNDIDKTSKALAQSKGEFKTYESTMKDLDNEQQHLKSSASLVESEYKKWQ
                     ATAGQSATESEKLAKAQEYVGKQSDIAEQKIEVLKKQLDATQKEFGETSTEALEMKTK
                     LNDAEREFEELSNAAKNVDTSTVDDIGKKLDMGNLMEATDHLSVIGDKLIDVGSKSIE
                     AAGKAQAMQAQFKQVFGSLEGEAQDAVEGMAEEFGMLPNTIKPVFTQYTSMFKGLGYD
                     TKEAMELAGDSTQLAADAAAFYDKSMDDASESLNSFIKGNYEGGEQIGLFANDTQMAA
                     YAVKHNLIPATEGAKKASEESLLAVEKAQSKYADAIKKHGEGSLEAREAALKLKDAQD
                     KINEELGPQTQKWSDLDEATKQAVRVQYAEDMQKLAGATGQASRESDGLENQMTRAKQ
                     ALEDFYASLGEDILPVFIKGLQAGAKALQGLAEWWSKLDGPMKNFILALGGILALLST
                     LAPVITAVVTIVGTFGSTVLLPIIGIIAGVAAVIAIVITAFQNWGAITDWFSDLWKKF
                     TDWLGDTWESIKESASSVWDGVKETWSGFVDWVQEIWQGVSDWFGELWSGLVEGASNI
                     WQGVQETWQAFVDWVSNIWNGVKEVWSIIWADIVGIVQIPWTLITSLIQAGINIIVGI
                     FDVAGQLLGAAWQAVWTPISDFLKNTWDTMTQWISIAWNGIVTTFHTIFDPVVAWWNG
                     IWTSISTTASNIWNSISATASSIWNSIKNTITSLVQAAATVIQNIWSTVSSWLGGIWN
                     SISSTASNIWNSVTSSISNAINAAKSAIQSVWNSISSWISGIWNGIKNTALNLWNGIT
                     STISSKVNDGKNAISSGWSNLTGIVSDIFNNVKSTIANIWEGIKKTVSAPIDWIRDKI
                     SSIFDNLNISIPHIPLPHFKLSGEFNPLKGKIPTLGVDWYAKGSVFNSPNIIGVGEAG
                     PEAVLPLKRSVLQEIGDRILSSTSVSSRAQTIQPVNNYEFNFTIDGNADEVTMKQTTQ
                     QIIDSITKVQNDNASAWR"
     gene            14268..15005
                     /locus_tag="IXR40_001815"
     CDS             14268..15005
                     /locus_tag="IXR40_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAQ4361654.1"
                     /translation="MTDCIHSIIDGFPDYLHKLALAERPTIPSPKRQRVETSVLGRLG
                     GLVQDYSFEDMSFTLHYNYLEDVEDHQAFKQSFYIMRHWLNYAKKLEFSDDPNVYYVI
                     QTIDIGDAENDIVEWGEFDVNITAKPFARVQEDVPITVDKPQSFNLLNNSLEESFPKI
                     IITPSATSCQFILNDYVFSFEGLVVGTDVVIDSDLMLCYEEQSDGDILDRSNKMKTMQ
                     YPTLQVDINYFNCTGLSKIQIYRNGLR"
     gene            15015..17306
                     /locus_tag="IXR40_001816"
     CDS             15015..17306
                     /locus_tag="IXR40_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361655.1"
                     /translation="MIDNLITIYDKNDANNLAEHLYDTQGLGALSDWLTATVSNKLNG
                     AEIFQGTYPISGTNADLIVEGRIIQCYVDENRAKQRLRIYYAKTSVIGNTIEVKAEPI
                     FNDIRKSVLNKYDSGTEKITASQAWQNAKTLAKPVIPSQFSFSSLVDTLANVKIEKAN
                     FLEFFGGKEGSILDRFHGEFLKDNNTLRHEKRLGTDHKIKAIYTKNLTGLDLEIDAQS
                     VLVGVYPFISSSSEGEDEITLPEEVIFTDYVDDYPAGYVSFVDFKDKATDVATLREAA
                     KDWLKTNIDKQKPQVSGSIELVPLRHQRGYEKFVDLEKVSMGDGVDVYHPQLKVNMSA
                     RIVEYTFNVLTNSYDKLVVGNVKTNFLENTENNVSNLINDAIDQLKNGGEISDLLNDI
                     VDHQTDMITGQNGGYVLLDPKEAPSRILIMDTPDKNTARNVLQINNAGIGFSKTGING
                     TYETAWTLDGGFNASFITAGEIVGITIRGTTLISDGADYRTSIANGKMTWYSKKVNKD
                     IMELEARDYVSADAGIVSYTMKTGGGFMIRNPQGNLVFSTWDNGNNRPFLSFGAPNFR
                     YSNASYVTSGDGSSLSINGSAGNSWEFKVAGRTMKFTSDGMLTLPGCFFGSWEDGKLA
                     RFEQSTVQVYKDFTVRGTKNSTVPTEHYGQRLLNAYETPEYYFADYGEAVTGDDGKVR
                     VDIDPMFAETVNLSRYMTHVTPTELVLCAVTHEDIDHFIIETSKPNVLVRWNLVAHRL
                     GYEDIRLKEDTAYDSTVLDQKRF"
     gene            17330..>18088
                     /locus_tag="IXR40_001817"
     CDS             17330..>18088
                     /locus_tag="IXR40_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361656.1"
                     /translation="MASSLYNLALDFSKELNYTKAIMARQGDKGITVTVKPFLNGLQM
                     DTSGGTFTLKGTTPSNRYVDNVATSVTSEEVTFSLDGTFMSEAGYYKHCYVEYRKDNQ
                     ILTTQDIIFFSLGVSDISQGQADEYVSQLEELIRKYNETFDAFMAEIKGRVDSLNQQI
                     TDLTGQAKTLQDKLDALKEEISKLGNLQVMYSNSIDFGGYDYSGKPNLMSKLKSSDFN
                     VGYHGSLTLDNEKLHFTSDGTGSIIMFTRINTPQL"
BASE COUNT         6371 a         2634 c         3868 g         5215 t
ORIGIN      
        1 aaagaaaata ttcttgactt attagattgc gtgaacgctt ggattctgct gtatggctat
       61 gaaaacatgc gtcctgaaat gaaagaatta gcttctaaat tatcggaagc gattgaagtt
      121 tagatttagc aaaggaggat acagaatgtt agtaaaaatt attgtaggag ttatcttttg
      181 gattatgact ttgatgctag gttactttat cggaaaagaa gaaggtcgta aagaaggcaa
      241 ataaaaaagc cggatcgctc cgactaacat aataaaacag acaagtttat tatatcacat
      301 aaaggagcgg tttgacttga tgcaattgtt acgagaggta gatttcaaac agacaagatg
      361 taatgcgaga gatgtgctga agaactttcg gcgtttggag cgtatggcag gtcgctcttt
      421 gatagatatt aagtcgccga ttataacgga tatgccgaag gcgccgaagc acggcaataa
      481 ggcagaggac gcgatcattc agatgatgga tatagaagca gagagagatg cgattctagc
      541 ggctttgatg gctcttagtc tgattagtcg tcagatactc tactacagct tctgcgacgt
      601 aaataagcat tctaattatg aaataggtca attgatacga ggatacggag agaagaatgt
      661 agagaagttg aaatccatcg cattgattga atttgctgaa gcatataaaa aaggcgtatt
      721 aattcagtat cgttgatttt gtagggtttt tgtagggata gtgtagggtt tttgagcggt
      781 ttaacgtgat attatggtag tgtcgaaaga ttaggaaaca ggacttcgac aaaataaaat
      841 gtaagggagg aaatctccct catcgtttaa ttaagcttcg atagacagca gcggaaatat
      901 taagaataag gatgtgaatt ttaactcctt ctaaattgtt cttattatct atcatccgtt
      961 gctgtctatt gtcattatgt cactgtggcg gaaagggtag acgcttaaaa ataaggtcaa
     1021 tacgtcgagg gatagcctta acgttttatg atttgaccat gcaatgttcg attcattgcc
     1081 agtgacttaa ggaacctacg gaaacaattc atcttatcgg atgccgatga attggctgac
     1141 tagtcgggat gctactagca gttagaaggc ataaaatact agcgcagacg tgcgccactc
     1201 tcaggtgtag gttaggagag aaacattagt tggggttatt aggaatacga taacctgctt
     1261 gcgacaaagc tttgtactgt cgcgttggtc atgaacagag acggtattct gtttcagtat
     1321 tcgttagcaa ccgagggatg tggcagtggt gaggtgcagg aagtatcaga cttgtttgtg
     1381 tgcaagttac tattacatat tagatcactc tttgagtggt ctttttattt tgcacaaagg
     1441 aggtaacaac aatgtataga ccacaatact tagaacagaa gtatgaagta atcactgttc
     1501 aaaatggtaa cagtgagata gtacgaaagt atagaagacc aataaagagc gatacatata
     1561 aacgaaagga aaacaatgaa gttattccat tgtatggcaa aagaatagct aagcattaaa
     1621 taagattgcg aaaggagacg ggacatgact gaggaattct atagatggct attacagttg
     1681 ataagagaag atcgtttggt taagttctat cagtcttcta aatggcgcag gcttagagag
     1741 aaagcgatga aacgagatca ctatgaatgc caagagtgta gaagactagg taagtatcat
     1801 agagtagaga acgttcatca tataaaggaa gtcaaggata gacctgactt agctttagat
     1861 ttagataatc ttatttgttt atgtgttgaa catcataatg aagttcatgg cagatatctt
     1921 acagcactag ataaacaaga gaagaagata gaaagctttg ctaacttcga tgcaagtgaa
     1981 aggtggtaag tgcatgatca tcaatgataa tggcagagag tatgatacag aaaagattga
     2041 agagtattca tcttatactc agggattaat taaacgtttg atatacgttc gctatgtagg
     2101 tattagggat ctgttatcag ataactgttg tagtaaatac aaagtgaatc aagtaagaga
     2161 agcgttgaat aaagataata acgtcgaaag aataaaaaat gtttttggat atagtattga
     2221 agagattaat tattacattg acttcgctga agctttcatt ccgatggtga gataaccccc
     2281 ccttaaaata aatcgcaaat tttttggggg tgatgaaacg gagggggctg tcaggaaaag
     2341 agattttttc gaactttatc atgaaaggag ggctaaaatg tttaaaaacg aattgtctca
     2401 aaatcgctac agagaaaaat tacgccgctc tttaataagc caattggaaa gtcagaaaac
     2461 aaatattgag ccattcttag ataatgttga tcgttatatc agtttatggg aaacggcgat
     2521 atcactggaa gaagatatat ccgagaacgg cattagactg gagaatggta aaaagaatga
     2581 atcagtagcg ttgcttgttt ctgtcaacaa acaaatggga ttgatgttgg ataaacttgc
     2641 cattactcct gaattggtag gtgaagcaaa tgaatcaatt cctgagttat aagcatattg
     2701 aaaattggtt caaagctata gaagaaggca ctatcaaggt atgcaaagag caattattgc
     2761 taaaaaatta tctagaagaa agagtcttta ctagagaaga tatttacttc gataagcaga
     2821 tggtagagga ttcaatcaat ataccagcac aatactttcc attcgaatta attccgtggg
     2881 aaaaatttct acaatgtttt atttatggtg ttcgatggaa aaaagataaa acactagtgt
     2941 tcaatagata tctttcatta atgggacgtg gtaatggtaa aactggtttt gcttcttgga
     3001 acaacttctt tctactaacc gctaaacacg gtattaaaaa ttatgatatt gatatctatg
     3061 ccaataatga aagccaagca aagactagtt ttgatgatgt atttaaagta attaaagatc
     3121 atcctgattt agataaaaaa gtatttaaag ctacgaagga agttattcaa aatatcgcta
     3181 caaacagcaa acttcgttat aacacggcaa atgctagaac aaaagatggg aagcgaccag
     3241 gtgcaaaccg ctttgatgaa attcacgaaa atgaagatta ttcaatgata aatgtggcta
     3301 cttctggtgg tggtaaaatt cgagattata gagaatttta tgatacaact aatggtcatg
     3361 ttcgtggtgg tccgcttgat gacattatag aagaatcaaa aatgattctt tctggagaac
     3421 ttggaattga caaggatgga gcagaatttt ctagtttgtt tccatttatt tgtcgcttgg
     3481 ataacgataa tgaagttgat gatcccgaca tgtgggaaaa agcttgtcca actattaatt
     3541 acaatgcaga tttaaaacgg aaaatgtttc aagaatactc tcaaatgcaa cgtaatgctg
     3601 gtttaagact tacgttcatg accaaacgaa tgaacagacc tatggaagat acacgatttg
     3661 ctgttgcttc atatgatgat gttctgcata cgaaagaaaa agaatttcct gaaaaaatgg
     3721 atgaagtgat aggaacagtc gattttgctg atagacgaga ttttgccagc gttgggttgc
     3781 taggaaaata cgataaagat gtttatttta cacaacatac ttttatccac gaatcagccc
     3841 ttcgattaca aaacatcaaa cgagaggtta tagatatttc tatagatcaa ggaaaatcac
     3901 agatcgttca tggaaaaaat atagaagctg attatattgt aggttggttt cttgaaatga
     3961 gtaataaata ttatattaaa aaaatcgcta tggatatgta ccgtgcaaaa atattgaagc
     4021 ccgctttaga agaagcaggt tttactgtgg aaattgttcg aagcggatct gttacacatg
     4081 gtatgttaaa agatctggtt gatgaccttt ttattaatca acgtttattt tttggtgacg
     4141 atgcgattat gcgttggtat tgcatgaatg tatatgaaga gcatatttct aatggaaata
     4201 tacgctatga aaaaatagaa cctgaaacta gaaaaacgga tggctttttt tcattccttc
     4261 atggtttgaa ttttttagat gatatttatg attctgctcc tgtaacagtc acaaatagct
     4321 cagtagaaaa tacaggaact ggatttactc ctctagtatt ctaacttgaa aggaggtgag
     4381 aaagtgggga tttttcaaaa ggcggtagga tacttcacaa aaaaagcaac ggttccttta
     4441 gaagaatact tttgtaaatt gcaagttgat tttgtgtatc gaaaatttgc gattgaaact
     4501 tgtattgatt tgattgcaaa tgcgatgagt aaagcggaat tcaagtcata tgaagatgga
     4561 aaaaataaaa agaatgatct ttactatagg ctgaatgtag ctcctaataa gaaaaataat
     4621 gcaacagaat ttagaaaaaa actgatcagg agattaatat tctacaatga agtattgatc
     4681 gtttctccgt ctaataattc tagcgaaata tttattgcgg atagttggga tgtcacagaa
     4741 tatgcattga aagatgatgt gttttctcaa gtgcaaatta acaacatagt ccttgataga
     4801 gaatttctag aaagtgatgt tatctatata aaatacgcag atcaacaaat taggcaacta
     4861 gtcgatgcgt attatcaagc gtatgggaaa ctcatttcta gtgccatgaa tgtttacaag
     4921 cgctctaacg ctcgtagata cgtactgaaa gggaatttat tccgaccgca agacaataca
     4981 acacaagatc aaatcaataa aatgatgaca tcacaattta aggcttttat ggaagctgat
     5041 aatgcaggtg cggtatttca attacaaaat gagtacacat tagaagattt cagcggaaac
     5101 ttccaaagca attcaagaga tataaaaaac ttaatagacg acatctttga gatgacagca
     5161 gcagcgtttc acgttccgaa aaacctacta aagggagaca tgagtgggtt atcggatcaa
     5221 gtggacgctt ttttaatgtt cgaaatcata ccgattgctg aacttattca ggatgcgttt
     5281 aacgctagtc tctatgaagt agaagaatac ttgtcaggga attttgtacg tgtggataca
     5341 actatgatca agattactag cttcaaagat ttggttgacg ctattgatgt aggcattaga
     5401 aatggagtat ttacaatcaa cgaaggaaga gagcgcgttg gaaatgatcg ctctgataag
     5461 gcgatggcag atgaaatatt tataactaaa aacaatcaac aagtatcgaa aggaggtgag
     5521 gcgaatgacg acaatgaaaa catttctagc agtaaagaat gaaggcgcag taccgcaaat
     5581 ttttattcag ggatttattg gttctagttg gttctttgaa gggaatactg acaagggaat
     5641 caaaaatatt ttggatagtc taggtgatca agaagaaatt gaagtagtaa ttaattcaaa
     5701 cggtggagac gtatttcaag ggattgctat tgggaactta cttaagtcaa ataaagcaaa
     5761 agttaacgtt gtgattaacg gcttagccgc tagtgctgct tcaattatcg caatggctgg
     5821 cgatactata aaaatctaca acaatgcaca attgatgatt caccgcgctt ccacatacgg
     5881 agaaggaaat gtcgatgact tccgtacgat tgctgaccaa ctggaatcaa ttgataaatc
     5941 ggtaaaggct tcatataaaa cacgattcaa tggcacagat gaagcattgc aagaacttct
     6001 tgaaaaagaa tcgtttatgg atgcagaaac agctttgagt tatggattgg tcgatgaaat
     6061 tatcgatgca gaaaatagct caggtactga agctaaaaaa gaacaaagcg ttgaagaaat
     6121 tttgaatgac gttaaagaaa aaagagcaga aaaaattgct gcatttacag cagcattaaa
     6181 taaaacattt ggacaaggag atgtaaaata atgacagtta aaaatttaaa aggtgtaaca
     6241 gctgcaagcg accaattgat gaaagctttt aaagatggta acgaagaatc ttttagcgca
     6301 gctatggtaa gcttatctaa ggaaattcag gataaaattt tagaagaagc aacagcaaaa
     6361 aatcaagatc aattagtatt aatgaaccgt ggtcagcgtg tattaactac acaagaaaca
     6421 aaattctata acgaagtagt gaaaaacgaa ggttttgcag gggtcgaaga attagtgcca
     6481 gctactgtat ttgaacgtgt atttgaagat ttagaacaat ctcatccact attgcaaaaa
     6541 attacttttg ttaacacaac tggtgtaaca gaatggattg tgtcacgtgg agtcaatcca
     6601 gcatggtggg gtaaactttg cgaagctgtt aaaaaagttt tagataatga ctttgatgta
     6661 attaacatga agcagttcaa gctatcaggt tatattcctg tatgtaaggc aatgcttgat
     6721 ttaggtccag tatggttaga tcgttatgtc cgtactgttt tagtagaatc attgagaatt
     6781 gcattagaac aagcaattgt tgatggtact ggtaaagata tgccagtcgg aatgatgcgt
     6841 gacatgagca aacaaactag cggagaatat gctgaaaaaa aagcagaacc tattacagct
     6901 ttagatgctg taactatggg cggtttgatg gcgcgactat caaaattcaa tatcgaaggt
     6961 gtgaatgatc cgatttatcg taatgtgaat ccttctgatg tggtcctaat tgtgaatcca
     7021 actgattact ggtctaaagt attcccagct aagactgtac taactgctaa tggagaatac
     7081 gtacaagtat tgccagtacc agtttcagat ttgcagtcaa cggctgtgcc agaaggaaaa
     7141 gcagttattg gggtagcctc agattacttc atgggtgtag gatctacact aaaaattgaa
     7201 gcttcagatg aataccattt tgttgaagac gaacgcattt atctagctaa acaatatgca
     7261 aacggtcaac ctaaacgtaa cgatagtttc attgtattag atattagcgc tttgggaact
     7321 actactacaa ctacaaaacc aacaaccaca acaactacaa cacaagcgta ggtgatcaga
     7381 atgaagtata ttctttgtca gccggcaatc aatcggttta aatgggagct tgaagtttgt
     7441 ttaactaatc tgaagaaact aggaatcaaa gatatcgtat tgcttttcag cagacacgat
     7501 gatcagattc ctattttttt tgagaaggaa tatggtgttg aagttcatgt gtacgatgat
     7561 ctgcgggacg acaaagagta tattccttcg attaaaccat atttatggtg gaaatattta
     7621 gaagaagatc attcgcgtga ggacgaccga tatttctata tcgattcgga tgtcattttc
     7681 aataaaagaa ttaatttgcg caaattgcct tctaaagatg atgtttggta ttgtagcgac
     7741 tgctgtagtt atctaagtct tgattatatt agaagctgtg aaaacggaga aaatattcta
     7801 aaagatatgg caaacattgt aaatgttaca gtagaatctt tggaaactat aaacactaat
     7861 tcaggaggcg cacagtgggt tattaaccgc cctaaagcga attattggaa aaaggtttat
     7921 ctggattcta atcggctata tcgctacctt agagggcaaa aaacaaatat acaaatctgg
     7981 acagccgaga tgtggccaca gctttggaac atgatgtatt tcaatattgg tcctaaagtt
     8041 cacgaggaat tagacttttg ttttgctact gatccaatag aaaaagttaa agaagtaaaa
     8101 atcttacaca atgctggagt aacaacaaac gatgaagatt tatttttcaa agggagatac
     8161 gtgacttcta cgccttttga tgaagattta tcatttgtaa acaagaaaaa atgctcttac
     8221 gcatatgtta aagcaattaa ggcggtggtt agatgacgcc tgaacaagtg actgaagaat
     8281 tgctaatagc tgtgaaggat aatatttacg ttacctggaa cgaagaagat gagtcaatta
     8341 aaaagatgat agctaaaaat gctgtttatc ttcaaagtaa agtgagtaca acactttctt
     8401 tttctcctga aagcttagaa tacggattgc taatcgaaag atgtagatac gactggaatc
     8461 gtgctttaga tgagtttgaa caaaatttcg ctagtgagtt attaggtttc attcaacatt
     8521 atgcgctaca agaatatatt gcaggtgatg tgaatggcga ataatcgtag actcgaagaa
     8581 acattcaacg atggttggtt aaagattttg acgcaaacta ccaaaagaaa tgaactagga
     8641 aaaaagattg gtgtagaaga tacagaaatc acttctttaa aatttagaaa tctttccatg
     8701 agagatagtg atataacagc tatggatgcg atgggatcga aattaactaa gaaagtaaag
     8761 actccatttc atccaatcgc caagaaattt aataaagatc aatattttat cgtaatcgat
     8821 agtatgcgtt acaacgttat ctatgccgat tacgataatt tttatatcta tttttatctt
     8881 gaaagtgtgg gtgaatatgg tgattgataa ttctaaagaa aaagaacgtt taaataagca
     8941 aatttctgct atcaaaactt ccttagaaga gcattttggc ctcaaactct ttcaagactc
     9001 cgtaggcgag gatgagctac ctgatgattt taattacttc attctcgaaa caggagaaat
     9061 agaaatgatc actgagccaa aatatagcgt gggtcaaaat ctatatctaa ctttctattc
     9121 agaaaataga gaagatttaa caggagattc actagatatt atttcattga ttcaaaatcg
     9181 ttcgattcgt tttcagagaa tggatcccaa tcatttaaaa ctagagaacc aagatcgcta
     9241 tatcgatcaa ttggtattta cgtttagacg attattgaag agtgattgtc atggctaaaa
     9301 atagttggga gctaaaaata aatggacatg atgaacttct tgtgcggatg gaacgctatt
     9361 caagcgagag cgaacgactg attaacgaag cattgaaatc aaaaggttcg gctattgcag
     9421 tggataggat tacagaaaaa attcctgttt ctgaagcaga tttaagaaga gggcaccaac
     9481 acgcaaaaaa tagtcgtcca cttaagactc aatacattaa tttgggtttc atcattagac
     9541 ctacaagaaa atttgagtat ttaaaatatc ctgatttggg gataggtact tctaaaagaa
     9601 atcagccgga cgaatttatg agaagaggat taggtcttgc acttgatcca attacagaac
     9661 ttctgattcg tcaattcgat aaattaaata aataggagga acaacaatgg ctaaaacaac
     9721 aacagtaaca acttttgaca atataagtat taaaagaatt tcttttaatt ttaagaatgc
     9781 aacaaatgca atttcaactg attgtaatgg acaattagat ggcgaaacag aaatgcagag
     9841 aattgtaaaa aaatgcggtt caacagaagt aaaatcgaaa tctaaaccaa tcaatatgac
     9901 ggtaacaatt actgcacatg taccgatgga agtttatcga cgcttcaatg ggttgaaaca
     9961 agatgaacgt attaaatcgg gaatttactc ttatggtcct gattccgtag gggaagattt
    10021 ctctcttgct gcagagatcg tggatgattt cgaagaaaaa aataagctga ttggtatgtt
    10081 agcatgcact tcgaatacag gattaacatt ctctattgaa aatggtgcgg atgaagtagc
    10141 tgcgttagaa ctagaaacaa aagttatgca agatgaattt ggtaaatttt atcatgaagc
    10201 aattgttgca gaacttgaag aagacttaac agatcaatgg atgacgaatc tatctgctga
    10261 tgtgattaaa aaaacttcag ttgtgacaac tacggccact caatcacagt aaaaaaaacg
    10321 gaggtagcga aatgaacgaa gattactcaa aaattgaact aaacgatgga acaattttga
    10381 atttagaacc taaactgaat atcaagaaat tattgatgat caatagagat tttaacacag
    10441 acgagtttgc aaaaatgtcg atgggaaaag gctctatgga tattacagtt attcaaggtg
    10501 caaaagccgt atatgtagct tatcgtcaag cgaacatggt cgattacatt tcattcgatg
    10561 aatttataga taaatgggat tttgatatgg aggttgcagt agctgtatac agtactatga
    10621 tgttcaaaca agcacgtgat gcctatcaaa aagaattcga aaaagcaaat aaggaaaaaa
    10681 agcttcaaaa gtaaaaatgc caaagctctt agttgaaacg tgggtcgatg tctattcgat
    10741 gttgaccgac gttttttcta tgccttcaga tttggtttta agcgatatct gtttagatga
    10801 cattttgcaa atggcttaca acaagagcgc ttatgaagga tggaagaact atgcaataaa
    10861 tcaatcccag aaaaactaaa ggaaaggagg taaaaaatgg ctaaaaagag aacggaagca
    10921 gaagtaactt tcatagctaa cgatgacgga ttgaaatcta cgttaaaaga aatcagtgct
    10981 gaattaacta aaaatagagc agaattaaaa ctagaacaag ctcaattaca acagactggt
    11041 tctgaatcag acaagttagg aagtaaatta tcttctttag aaaagcagta tgaattacaa
    11101 agtcaaaaag ttgaagtaac tagtcaacgt ttagccaatg ccaaaaaata ttatggagaa
    11161 aattccaccg aagttcagaa acttgaaaga gaactgatta atcaacaaac agctcagcaa
    11221 aggttatcta atgatataga taaaacgagt aaggcattgg ctcaatctaa aggtgaattt
    11281 aaaacgtatg agtcaactat gaaagactta gataatgagc aacaacatct aaagtcaagc
    11341 gcatcattag tagaatccga atataaaaaa tggcaagcaa ctgctggcca gtctgctaca
    11401 gaatctgaaa aattagcaaa agcacaagaa tatgtcggca aacagagtga tattgctgaa
    11461 caaaaaatcg aagtgctaaa aaaacaatta gatgccacac aaaaagaatt tggagaaaca
    11521 tctaccgaag ctttagaaat gaaaactaag cttaatgatg cggaaagaga attcgaagaa
    11581 ttaagtaatg ctgctaaaaa cgttgatacc tccacagtag atgatatcgg caaaaaactt
    11641 gatatgggta atttaatgga agctactgat cacttgtcag tgatcggaga taagcttatt
    11701 gatgtaggta gtaagtctat tgaagcagct ggaaaagcac aagctatgca ggcccaattt
    11761 aaacaagtct ttggctcttt agaaggggaa gcacaggacg ccgttgaggg aatggctgaa
    11821 gaatttggaa tgttaccaaa tacgatcaag cctgttttta cacaatatac gtcaatgttt
    11881 aaaggacttg gatatgatac caaagaagct atggagttag ctggtgatag tactcagtta
    11941 gcagcagatg cagcagcttt ttacgataag tctatggatg atgctagtga atctcttaat
    12001 tcatttataa aagggaacta cgaaggtggg gagcaaatag gtttatttgc taatgatact
    12061 caaatggcag cttatgctgt taagcataat ttgataccag cgactgaagg agcaaaaaaa
    12121 gccagtgaag agtcattgtt agctgttgaa aaagcacaat ctaagtatgc tgatgctatt
    12181 aagaaacatg gtgaaggatc tttagaagca agagaggctg ctttaaaact taaagatgcg
    12241 caagataaaa taaatgaaga attaggccca caaacgcaaa aatggtctga tttagatgag
    12301 gctaccaagc aagcagttcg agttcaatat gctgaagata tgcaaaaatt agccggtgct
    12361 acaggtcagg ctagtaggga gtctgatggt ttagaaaacc aaatgacaag agcaaagcaa
    12421 gcgttagaag atttttatgc ctcattgggt gaagatatac tgcctgtgtt tatcaaaggg
    12481 ttgcaagcag gagcgaaagc tttgcaagga ttagccgaat ggtggagtaa acttgatggg
    12541 ccaatgaaaa atttcatttt agctcttgga ggaattctag cattattaag cacattagct
    12601 cctgttataa ccgcagttgt tacgatagtt ggcacatttg gttctacagt tttgctgcca
    12661 ataataggaa ttatagcggg cgttgcagct gtaatagcga ttgtaattac agcgtttcaa
    12721 aactggggcg caatcactga ctggtttagt gatttatgga aaaaatttac cgattggtta
    12781 ggtgatacct gggaaagtat aaaagaaagt gcctcatcag tttgggatgg agtcaaagaa
    12841 acctggtctg gatttgtaga ttgggttcaa gaaatttggc aaggagtttc tgattggttt
    12901 ggagagttat ggagcggatt agttgaagga gcttccaaca tctggcaagg agtccaagag
    12961 acttggcaag cattcgttga ttgggtttca aatatttgga acggagtcaa agaagtatgg
    13021 tcgattattt gggcagacat tgtaggaatt gttcaaatac catggacatt aataacgtca
    13081 ttgattcaag ctggtattaa tattatcgtg ggtatctttg atgtagctgg acagttatta
    13141 ggcgcagctt ggcaagctgt ttggacacct atttctgatt tccttaaaaa tacttgggat
    13201 actatgacac aatggataag catcgcttgg aatggaattg taactacatt ccatactata
    13261 tttgatccag tagtggcatg gtggaatggt atatggacat ctattagtac tacggcttca
    13321 aatatttgga attcaattag tgcaacagct tctagtattt ggaacagtat caagaataca
    13381 atcactagct tggtacaagc agctgctaca gtaattcaaa atatttggtc aactgtatct
    13441 agttggttag gtggaatttg gaattcaatc agctctacag catcaaatat ctggaatagt
    13501 gtgactagta gtataagcaa tgctataaac gcagctaaaa gtgccattca aagtgtttgg
    13561 aatagtatat cttcgtggat cagcggaatt tggaacggta tcaaaaatac tgctttgaat
    13621 ctttggaatg gaattacaag cactattagc tctaaagtaa acgatggaaa aaatgcaatt
    13681 tcaagcggtt ggtccaatct aacaggtatt gtttccgaca tattcaataa tgttaaaagt
    13741 acaattgcta acatatggga aggcatcaaa aagactgtta gcgctccaat tgattggatt
    13801 agagacaaaa tcagtagtat ctttgataat ttgaatattt ctataccaca tattccgtta
    13861 ccacatttta aattgagcgg agaattcaat ccattgaagg ggaaaatccc aacgttgggt
    13921 gttgattggt atgcgaaagg tagtgtgttt aattctccga atattatcgg tgtcggcgaa
    13981 gcaggacctg aagcagtttt acctttgaaa agatctgtgc tgcaagaaat tggtgatcgt
    14041 atcttgagta gcacatcagt ttcatctagg gcacaaacga ttcaacctgt gaataactac
    14101 gaattcaatt tcacaattga tggtaacgca gatgaggtta ctatgaagca aacaactcaa
    14161 caaatcattg atagcattac aaaagttcaa aatgataatg cttcggcatg gcgttaaaca
    14221 ggagagtatt tctcctgttt ttttagtatt aaaaaggatg tgaaaaaatg actgattgta
    14281 tacattctat aatcgatgga tttcctgatt atttgcataa attggcttta gctgaaagac
    14341 caaccatacc ttctccaaaa agacagagag ttgaaacttc tgttttagga aggttaggtg
    14401 gcttagtaca agattactcg tttgaagaca tgtcgtttac attgcactat aactatttag
    14461 aggatgtgga agaccatcaa gcgttcaagc aatcgtttta tatcatgcgt cattggttaa
    14521 attatgcaaa gaaattagaa ttctctgatg atcccaacgt ctattatgtt atccagacta
    14581 tcgatattgg ggatgcagaa aacgatattg ttgaatgggg agagttcgat gtaaatatta
    14641 ctgcgaaacc attcgcaaga gttcaagaag atgtacctat aaccgtagat aaaccacagt
    14701 catttaactt gctgaataat agtttagaag aaagttttcc aaagattatc atcactcctt
    14761 cagctacttc atgccagttc atcttaaatg attatgtgtt tagttttgaa ggcttagtag
    14821 taggaactga cgtagtcatt gatagtgatt tgatgctttg ctacgaagag caatcggacg
    14881 gagatatttt agatcggtcc aacaaaatga agaccatgca atatccgaca ttgcaagtgg
    14941 atattaatta ttttaattgt actggtttga gcaaaataca aatttatcgt aatgggttaa
    15001 ggtaggtgaa atagatgatc gataatttaa taactattta cgataaaaac gacgcgaata
    15061 atttagctga acatttatat gatacgcaag gtttaggcgc tttgtcagac tggttaacag
    15121 ctactgttag caataaatta aacggagccg agatatttca gggtacttat ccaataagcg
    15181 gaactaatgc agatttgatt gtagaaggac gtattattca gtgttatgta gatgaaaatc
    15241 gagcaaaaca gcgtctacgg atttattatg caaagacttc tgtaataggc aatacgatag
    15301 aagtaaaagc tgaacctatt ttcaatgata taagaaaatc ggtgttgaat aaatatgaca
    15361 gtggaacaga aaagatcact gctagtcagg catggcaaaa cgcaaaaact ttagcgaaac
    15421 cagttattcc ttcacagttt tctttctcgt cattagtaga tacgcttgct aatgtgaaga
    15481 tagaaaaggc gaatttttta gaattctttg gtggaaaaga gggatctatt ctagatcgat
    15541 ttcatgggga atttctaaaa gataataaca cattacgtca tgaaaaaagg ctaggcacgg
    15601 atcataaaat caaagcgatt tatactaaaa acttaactgg tcttgactta gagattgatg
    15661 ctcaaagtgt tttagttgga gtttatccat tcattagcag ctcttcagaa ggagaagacg
    15721 agatcactct accagaagaa gttattttca cggattacgt ggatgattat cctgctggat
    15781 atgtttcttt tgttgatttt aaagacaaag cgactgatgt agccacatta agggaagctg
    15841 ctaaagactg gttgaaaaca aacatagata aacaaaaacc acaagtgagt ggttcgattg
    15901 aattagtacc attgaggcat caaagaggct atgaaaaatt tgttgatcta gaaaaagttt
    15961 cgatgggtga cggagtagat gtgtatcatc cacagttaaa agtgaatatg tcagcgagaa
    16021 ttgtggaata tacgtttaat gttctaacca attcatacga taaattagtt gtaggaaacg
    16081 tcaaaacaaa cttcttagaa aacacagaga ataatgtcag caatttgatt aatgatgcca
    16141 ttgatcaatt gaaaaacggt ggcgaaatca gtgatttact caatgatatt gtagatcatc
    16201 aaactgatat gattactggt caaaatggtg gttatgtttt attagatcct aaagaagcgc
    16261 ctagtcgtat tttgattatg gacacaccag ataagaatac cgcaaggaat gttttacaaa
    16321 tcaacaatgc tggtattggt ttttctaaaa ctggcattaa tggaacatat gaaacggcat
    16381 ggacgttaga tggcggattc aatgcctcgt ttattacggc tggtgaaata gtaggaatta
    16441 ctattagagg tactacatta attagtgatg gtgctgatta tagaacaagt attgctaatg
    16501 gcaaaatgac ttggtactca aaaaaagtta acaaagatat tatggagcta gaagcacgtg
    16561 attatgtaag tgctgatgcc ggtattgtat catacaccat gaaaactggt ggtggtttca
    16621 tgattagaaa tccacagggt aacttggttt ttagtacgtg ggataatggt aataacagac
    16681 cgtttctatc ttttggtgcg cccaatttca ggtatagcaa tgctagttat gtaacttctg
    16741 gcgacggtag ttctttaagc attaatggta gtgcgggtaa ctcatgggaa tttaaggtag
    16801 ctggtaggac tatgaaattt actagtgatg gtatgctaac gttaccaggt tgtttttttg
    16861 gttcatggga agatgggaaa cttgctaggt ttgaacaatc aacggtacaa gtatataaag
    16921 attttactgt tagaggtact aaaaactcaa ctgtaccaac agaacattat ggacaacgac
    16981 tattgaacgc ttatgaaact ccagaatatt atttcgctga ttatggggaa gccgttacag
    17041 gtgacgatgg taaagttcgt gttgatattg accccatgtt tgctgaaaca gtaaatctaa
    17101 gtcggtatat gacacatgtg acacctacag aactagtttt gtgtgctgtt actcatgaag
    17161 atattgacca tttcatcatt gaaactagta agccaaacgt attagttaga tggaatttag
    17221 tggcacaccg tctagggtat gaagatatta gattaaaaga ggatacagca tatgatagca
    17281 cagtgcttga ccaaaaacgt ttttaaaacg aagacaagga ggtatataaa tggctagcag
    17341 tttatataat ttggctttag atttcagcaa agaattaaac tacaccaaag ctattatggc
    17401 tcgtcaaggt gataaaggga ttacggtgac ggttaaaccg tttctaaatg gcttgcagat
    17461 ggatacgagt ggcggaacat ttactttaaa aggaacaaca ccatctaacc gttacgtaga
    17521 taatgttgca actagtgtaa ctagtgaaga agtcacgttt tctcttgatg gcacatttat
    17581 gagtgaagca ggatattata aacactgcta cgtagaatat agaaaagaca atcaaatttt
    17641 aacaacgcaa gatatcattt ttttctcact aggagtgtct gacatttcgc aaggccaagc
    17701 cgatgaatat gtttcgcaat tagaagagtt gattcgaaag tacaacgaaa cttttgatgc
    17761 ttttatggct gaaatcaaag gtagagtgga tagcttaaat caacagatta ctgatttaac
    17821 tggtcaagct aaaacgctac aagacaagtt agatgctctg aaagaagaaa tttctaagtt
    17881 aggtaactta caagtgatgt acagtaacag catcgacttc gggggatatg attatagcgg
    17941 taagccgaat ttaatgtcca aactaaaatc gagcgatttt aacgttggtt accacgggtc
    18001 actaactttg gataacgaaa agttacattt tacttctgat ggtacaggaa gcattattat
    18061 gtttacgcgt attaatacac ctcagctt
//
LOCUS       DACGEU010000056        17754 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.056, whole genome shotgun sequence.
ACCESSION   DACGEU010000056 DACGEU010000000
VERSION     DACGEU010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17754)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17754)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17754
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.056"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(17..2095)
                     /locus_tag="IXR40_001818"
     CDS             complement(17..2095)
                     /locus_tag="IXR40_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HAQ4361657.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            complement(2108..2383)
                     /locus_tag="IXR40_001819"
     CDS             complement(2108..2383)
                     /locus_tag="IXR40_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361658.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            complement(2745..3200)
                     /locus_tag="IXR40_001820"
     CDS             complement(2745..3200)
                     /locus_tag="IXR40_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361659.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            complement(3354..4562)
                     /locus_tag="IXR40_001821"
     CDS             complement(3354..4562)
                     /locus_tag="IXR40_001821"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HAQ4361660.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            complement(4674..5006)
                     /locus_tag="IXR40_001822"
     CDS             complement(4674..5006)
                     /locus_tag="IXR40_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HAQ4361661.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            5154..6029
                     /locus_tag="IXR40_001823"
     CDS             5154..6029
                     /locus_tag="IXR40_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAQ4361662.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            complement(6111..6692)
                     /locus_tag="IXR40_001824"
     CDS             complement(6111..6692)
                     /locus_tag="IXR40_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IDEAL domain-containing protein"
                     /protein_id="HAQ4361663.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(6698..7957)
                     /locus_tag="IXR40_001825"
     CDS             complement(6698..7957)
                     /locus_tag="IXR40_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HAQ4361664.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            complement(7959..9005)
                     /locus_tag="IXR40_001826"
     CDS             complement(7959..9005)
                     /locus_tag="IXR40_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361665.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            complement(9240..9515)
                     /locus_tag="IXR40_001827"
     CDS             complement(9240..9515)
                     /locus_tag="IXR40_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008214712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HAQ4361666.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(9758..11068)
                     /locus_tag="IXR40_001828"
     CDS             complement(9758..11068)
                     /locus_tag="IXR40_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HAQ4361667.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            complement(11250..12479)
                     /gene="rpsA"
                     /locus_tag="IXR40_001829"
     CDS             complement(11250..12479)
                     /gene="rpsA"
                     /locus_tag="IXR40_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HAQ4361668.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            complement(12614..13294)
                     /locus_tag="IXR40_001830"
     CDS             complement(12614..13294)
                     /locus_tag="IXR40_001830"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HAQ4361669.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(13343..13978)
                     /locus_tag="IXR40_001831"
     CDS             complement(13343..13978)
                     /locus_tag="IXR40_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAQ4361670.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(14044..15447)
                     /locus_tag="IXR40_001832"
     CDS             complement(14044..15447)
                     /locus_tag="IXR40_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HAQ4361671.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATEQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWGTILLNLFKKNMEH"
     gene            complement(15434..16465)
                     /locus_tag="IXR40_001833"
     CDS             complement(15434..16465)
                     /locus_tag="IXR40_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361672.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESAVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            16496..16717
                     /locus_tag="IXR40_001834"
     CDS             16496..16717
                     /locus_tag="IXR40_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HAQ4361673.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(16882..17619)
                     /locus_tag="IXR40_001835"
     CDS             complement(16882..17619)
                     /locus_tag="IXR40_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HAQ4361674.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
BASE COUNT         5054 a         3774 c         2980 g         5946 t
ORIGIN      
        1 gaaaattttt acctttttat tttattggac tcgttttttt tgactttgct cgaaacgcaa
       61 atcggaaaga aaagttatca gatggtttgt tcatcgtata agattctaac aaattgatat
      121 tcctgcgata gctgttcgca gaaaacgtcg tgattttttc agcaacttcg tattcatcaa
      181 tgatttttct ttcaagataa taacctctta gcattttttt cgtaaacaga ctatcttgct
      241 ggatcatcca cgaagaaatc aaattccccg agttcatttt tattccttca agtttgcgtt
      301 gctggataaa aaattgaacc atcgtttcat cataaatatc agtcaagtta tctaaacttt
      361 caataatcaa ctgagtattt ttttgatatg tctctctgat ttcttggata tcttcatcac
      421 taataaatgt ctgacgatca gcatatcttc tttgccaaaa cattttcgga tggagaacga
      481 ttcgcattaa cctacggaca acaatgaacc aaaagccgat aaaagacaaa atctggcttg
      541 tgatagaatg ttcgaatcga gaaagaaaac gggagtaaaa acgataacca ttagaagaaa
      601 gcttgcccga acgataactt tcatccaatc catcccgttc gatcgacaaa atcagtgctt
      661 gtatttcttg tacttcttgc ttttcatcat cggttaaatc ttccaagtac agatcacgta
      721 tccgttcttg ataattttct atcactgctt cagtggctaa aaattctttt gtattacgat
      781 caatttcctt tatttctttt cgcaaaactt caacgacctc ttctaaaatc atcaaagcat
      841 tcaaatccgt gcttttcgct tcctctgttt ccgtcagcat aggcaagaca atgatcccta
      901 tgaccaaagt cactaagatg acacccgccg tcagaaacaa aagcaaagac cgctggtaaa
      961 acatcatatt attgattgaa aatggcaaaa taaaaatcgt agccaaactg actgttccct
     1021 ttacaccgcc aaatgttaag atcaagatct cgttcaactg ttttttgaac tttttactgc
     1081 catctttgaa tacataaaaa agactgatag aaatgaatct gatcacaaaa agcatgacag
     1141 agattaatac gataatcgct aataaaagac cgtttggata taaaccgtct ccccatactg
     1201 gcgagaacac ttgcgtcaat tcgattccta aaaatataaa tactaatgca ttcagtgtaa
     1261 aagcaatagt tgtccatgta ctgtgggaca agctcgacaa ttctgcatca aacacagaga
     1321 ttttcctaaa accagaagct tggagaatac ctgctgccac tgcagcaatg attccagata
     1381 catcaaatgc ctctgccaat acataggcta gaaaaggaag caaaagttcg atcagcagat
     1441 accctgtgac atcttgtgct gatgcttttt cgatcaaatg aattattttt tgtttgaacc
     1501 agacaagcaa aaagccgatc aaagctcccc caatactaga aactactaga ctcatccccg
     1561 cgtttactgc tgaaaaagat ccggtgatca gcgcaccaag agcaaactgg aaggcagtaa
     1621 caccagatgc atcattcaaa agaccttctc cttccaaaat atgcatcgcc tttttaggga
     1681 tattcactcg tccagaaaga gaactgactg ctaccgcatc tgtcggacct aacgctgctc
     1741 caaaagcaaa gcaggcagca agtgggacac ttggcaacag gaatgataac gtcgcaccta
     1801 ccccgacaag ggtcaaaatg actcctccaa atgccaagaa caaaattgtc ccgaaatttt
     1861 tgagaatcga agaaatatct gctttttctc cttctctaaa taacaatggt gcaataatca
     1921 taactaagaa caattcaggt tcaaaatcga ttgattgtcc ccactctgtc agacctaata
     1981 ccactccaag gaaaatttgg atcagtggag ctggaatcat tggcaaaatg cggctagcta
     2041 tgttcgataa ggtgatcgtt actgcaaata caataactaa ctcagcaaat tccatcgtcc
     2101 atccccttta ttttttattt tgtgtaagca tttttaaaaa ttgttctttt ttctttaaaa
     2161 ttttggtttc gactacttca acctgtgttt ggttcccctc taattcacac tgtacacgtt
     2221 ttgactccaa acgaagcaga tcatgtttca gacgttccaa ctgacgatac atcaatatat
     2281 ttcttttacg caacttacaa agtatttgac ggcggtcatc catcgaaagg gcgccatagc
     2341 gatcatgcaa cagttttttt tgttgttcaa aactctctct cattttccag atctcctata
     2401 cacaaacttc catcattata gcaaagttct ttttggatga aaaatatttc attgtttcat
     2461 cgtttattgc tagttagaaa tttccataaa tttttcaacg cctcattcta ttccaaatag
     2521 tatcagatat caagtaaaac ttaagaaaga taaaagtttc tgacaaaagg atgtttactt
     2581 tcccattcct gcctttcttg ttcttttatc acaacaaaaa aatggggctg cgacaaaaat
     2641 cttgtcacag tcccttattc tgaataaacg gtgtggaaga gacagcctat cagtagtaat
     2701 aagacacatc tctttcacag cctcattttt gcgtaaaaat cgatttattc gaaaaattcc
     2761 ccgtatacat cttctacacg ttgatctgga ttgatcacga tatacaagtt acctgttttt
     2821 tcgctgattt ttgttgattg atattgattg tctaatcctt ctgttccttt atctagatat
     2881 gggaagtaca caagatcagg tgtgccattt cggtaaagga tttccattcg ctcgatatct
     2941 tcgtatttca atgcgcgatt aaacatgccc atttccagtc cgcctaggtt gatatcatgt
     3001 gtcgcaactg cgtccccttc atggaagatt tcgattttaa atccagcaca cggatggatt
     3061 tcaacaaatt cactgccatt gattcgtcca aaacttgttg tgatttgttt gatccaaaga
     3121 tcgccgatat gacggcggtt gatcgtccag gtttctccat ttctaaaata aaattttagc
     3181 gctgtcattt ctttactcat taaaaagact cctttatgat gtaatttatt cttgtactac
     3241 ctcagtttag cacaaattta tgtaagtggt cacatcttat gttttttctt ctaatgacgt
     3301 atctgcccac tttaagtagc caacaaagct gagcagatac agtctagtgt tttttaaatc
     3361 aatttttctt tcgataaaaa atccaaaacc tgttttttat cattttttat tctttgttct
     3421 acgacggctt tttcagctaa ttgcaaagct tcactaaccc acttaccagg tttttttcca
     3481 gtttcttcta gcaagatttt accatctact gctaattcgc ttaatgactt gataggtaaa
     3541 cgatcatagg attctcctac ggcatccatc tgaggtgttt cgtcaaaata gatcatcaat
     3601 tcttctactt gcagtgcatg ttttttgcct aagaagtaca attcgaatgg ttccaaagct
     3661 ccagtttctc gttgtcgtag tccttggaca agtgcttgaa cgtctttaat catttggtta
     3721 gaacacttcc acgatttcaa aaaggaacga atctcatttt cttttagatc cagttggctg
     3781 atcaataatg cccatgcttg gctctcttct ttcaatggga cggatggtaa ttcagcaaaa
     3841 cgtaaaagtg cttcgccttc ttctttcaaa ccgggacagc aaatgtagca ctctgtttca
     3901 ataaatgcat ggattcccgc ggcccgttca tttcccaaga gcatcttgat gaattccaca
     3961 tttatacgtt ctacagatat tttacctaat agctcgtggt tttctttgat ggcgtagaag
     4021 gtttcttcct ctaatttgaa ccctagttga ctgacaaaac gcaacccgcg catcattcgt
     4081 aaggcatctt catggaaccg ctcatgagga ttgcctacag ctcgcaagat ctgttcttct
     4141 agatcttgca gaccatcgaa caaatcgatg atttctccat cttctttcaa agcaaacgca
     4201 ttgatcgtaa aatctcttct tttcaaatct tctgccaacg aacgaacgaa ttcgacatga
     4261 tctggtctac ggtagtcctg ataagttgat tccgtccgaa atgtggtgat ctcatattgt
     4321 tcatcatttt ctaataccaa cacagttcca tgttcgatcc caatatctat cgtttttgga
     4381 aaaagctgtt tgatttcttc tggaaatgcg cttgttgcga tatccacatc atggattggc
     4441 tggttcagca agatatcacg aacacttcca cctacaaaat aagcttcata tcctgcattc
     4501 tctaattttt tcagaactgg aattgccttt tggtattcca gaggtaattg ttttaatttc
     4561 atttttccaa cctttcctgc gtgtttcttg tcctgagata aagactcagt tgcatggtga
     4621 ctgtttgaca agtccgtttc agagtcttca aggccaggac cacttcatct tgtttactcg
     4681 tccttacgct caaagcgatt atggtctctt tgattgaatt tttccatgtt tttttcaaaa
     4741 acttcagtta agtcgatatt caatgaatta gccatgatca tcgtaacgaa taaaacatca
     4801 ccaagttctt ctgctaccga gttaactggt tcagaagcct ttttgctttt ttctccataa
     4861 gtgtggttga cttctcttgc caattcacct acttcttcag ttaatcgagc catctgagct
     4921 aatggagaga aataccccac cttgaattgc tggatatatt catccacttc ctgctgcata
     4981 ctgtataaag aacgcttttt atccatcttt ttccctccaa aactatctta ccaaaacttt
     5041 aacgcaaatc ctagataaga gcaattgaga aaatcgaatt tccatgctac atttaggaag
     5101 gaatttctaa atggaaattc tgtgaaaata cataattgaa agctggaatt catatggtca
     5161 aacgaaaaac agtaaaagaa gttcttttta tcattatagg aacaagtatt tatgcatttg
     5221 gtcttgttta cttgaacatc gctaatcatt tagcagaagg gggagtctca gggatcacct
     5281 tgatcttaag agctttattt ggtattgatc cagcttatac gactttatta atcaacatcc
     5341 cattgatttt actaggagga aagatcctcg gtaaacgttc cttggcctat actgttctag
     5401 gtacactttc tttgtcattc tttttatgga tctggcaaag ggttccacta gaaatcaatt
     5461 tacagcatga tctactgatc gtttctctac ttgcgggttt agttgcaggt gtaggaagcg
     5521 ggatcgtcta ccgcatgggt ggaacaacag gcggcagtga tattatcgct cggattttag
     5581 aacaaaatta cggcatcact atggggcgtt ccctattggc atttgatatc atcgtcttac
     5641 ttgcttcatt aacctatatc gacttgaaac gtatgatgta tacgttgatt gtttcgtatg
     5701 ttttcagtcg tgtgattgat tcgatcttag atggcggata ttctgcaaaa ggtctacttg
     5761 tcgtctccaa caaaagcgaa gagattgcac cactactgat gaccggtctg caaagaggtg
     5821 tgactttcct ttctggagaa ggcgcattct ctggtaattc aaaaaaaatc atctatatgg
     5881 tcgttagctc tagtgaatta actgaagcta agaggatcgt ccacgagatt gacgaaaaag
     5941 ctttcctttc aatcatcaat gtgcatgaag tggaagggca aggctttact tatttgaagc
     6001 cacagacaag attactgaaa aaactataag aaaaaagaca aagataggct atgaggaaag
     6061 attccacatc cagctgacct ttgtcttttt tagtactata ctatttttaa ctaattgtta
     6121 tgttcactta cccggttact tttcttttgt gtctgcaaaa ggatctttcg gttaacttca
     6181 tcagataatt tcaaaaaagc atccctatct ccatcttcta gtgcttgatc gatttgagca
     6241 taaagcattt ttagttttgc ctcttcttct ttttcttgaa aatatcgttc aattaattca
     6301 gtatcttctt cactgactga agaatcccaa gaagaaaatg gattgtcttc taagatagat
     6361 agatattctc ttgtctgcca agcattttcg aatatacatt ccacatataa aggctttttc
     6421 caattcaaac ggatttcatg aaaaatctgg tctgtgtccg taaattcttt tccctgcaaa
     6481 aacaatttca tgggttcccc ttcaacagat agatcactga tctgcagtcc tcgatccgca
     6541 aaattcgccc cttcaacaaa gtggacattg cttaaaatcg cttcatgatt ggcaagataa
     6601 ttcaagatcc aaaaaacttc tcttcggcta aaagatacat gattgaccat ccacgttaaa
     6661 aaattcttct tttcccgtac atcaattagc atttttctca cctctctgtt aggtcatcta
     6721 ataatgacag tgcctccata tctcctggtt caagtgttaa ataataagtc aataattctt
     6781 gcgctctttt cagctgccct tcttctctta agaaaaaggc atactctttc aagaaatctg
     6841 gttcatgtga tagttcatga taagcctgtt catagtgtac agctgcaacg gtaaagtctt
     6901 ctaattcatt ataagcatgg gctaggttcc attctgcata aggattagca gtttcttcca
     6961 tctgattgat cacttgtatc acatcttcat atctttcatc atccaagtaa agattactta
     7021 aagtaagtaa tgtttcatct tgtttgtctc ctacttctaa agctttcagt aaaagttctt
     7081 ctgctcgctg tctatcatgc agacggaaag cattttccga ggccaggtga taaagttcga
     7141 cttggtaagg attttctttg attccttctt ctaacactgt ttgtgcttct tcaatcattt
     7201 cttcttcttg aagagcttgt cctagatata gatataacga ttgataatgc ggattaactt
     7261 ctcgaagttc ttccagatag ttgattgcct gctgattttc tttcaattga agattcgtaa
     7321 aagctagctg gaacagtcga tcatctgtcc tttcttcttt cagtgcttct tctaaaggta
     7381 cgatagctgc ttcgaattct ccttgcatac ttaaggattg tcctaaacgt tcctgcatcg
     7441 agattcctga aatttcattt atcccgcttg ccaacaatgt ttcataaacc actgctgcct
     7501 ctttgaaacg atcaactgaa aaatacaatt cagctagcgc aaactggatc aatggttcat
     7561 caggaagcaa cccagctgct tctttcaatt ttgcttcact cacttcaggg attccgataa
     7621 cttggtacaa atcagctatc gccaataagc tttgcggata gtaatcactt tgcttatcca
     7681 ctttttccag gtattcaaaa gctaagtcga tctcattatc ttcgattgca atttctgcta
     7741 acgggatgtt cagtccgtca ttttctgggt attggttgat cagttgttca aaaatctgtt
     7801 ttgcttcgat caaaaagcca atagccagca attcttcgcc tagttcagct aatatatctg
     7861 ctgggtcttc ttttaatgct ttttctaaaa agatttgtgc ttgtgacaag tcttcatctg
     7921 ataaagcttg caacattttt tcgctatttg tattcatttc aattccctct tatctcactg
     7981 acgatttgtt gaaataccgt cattgttctc aataattctt tttcgtttgg atgttggtat
     8041 ccgtctatta tacctatttt ttctaaaaca agtatttttt tgcttttttc tgccaaaaaa
     8101 agaacttttt ccaaatactc catctttgaa atctgttcca gccagtggat tggatagcca
     8161 agcaagtcca gccacacaaa aaagtttttt agttggaaat caaaaggata tgcttggaga
     8221 ttccacacga aatgaaacat cattcctaaa aattttttca tactagcaga aagtagatgg
     8281 ccattttcgg tcagataaaa agcttgttca aacagtttac cataatttga caggttttct
     8341 gcctctaatt gataaaaata gatcatttct tcgatcatcc cggcaaacgg ccgagtcgtt
     8401 aattgctttt tatttggata gtttttatac agattttgca aaaaacgatg atcacaaatc
     8461 attccgcaac agataaaagt caaaaagtca atctgctttc cgtccacctg ccgctcgctg
     8521 attgtttgat cataaacgat gcgttctggc agattgatgg tttgcagcac tacacgattt
     8581 ggtagctgca aaatcgtccg ctgcggtgtt aatgctcggc ttagagaacg gatcgataca
     8641 gggatcatcc atagtgatga atcaagggtt gtatgttttt gaaaaaaacc tgccagatcc
     8701 atgatccctt catttccaaa tccgatgata aacatggatt gattttcggg atagcgtttg
     8761 acgaaatcaa gcaggttctt taattctgtt aaatgattgc attgagtgtt ggcacaaata
     8821 taccagtcat tgtttgcttg atttgcaaat aacgggttga tcttatctgc aaacaaatca
     8881 taatagcgct gattcgttaa aaataagatt ggctgatcaa tggaaagttc tcttagctga
     8941 ctgactagcg tttctccgta aaacactttc gtcaacgcat cttctacttg ataatcaagt
     9001 tccatacgca tccctcctct tcttattttt attttaccat tagtaagcaa attctagaaa
     9061 agataagagc aaagctcacc tcataacttg caaataaata aaaattaaat aaaatacatg
     9121 tgttttctat gtatgacata cggattcgga atctctgtct cttatttatt ccttttctgc
     9181 taggaaataa aaagaaaagc acttgtagcc ctagagccac aagcgctttt tcaactgtct
     9241 tatttaacag cgtcttttaa tgctttacct ggtttgaatg caggtacttt gctagctgga
     9301 atttcgattt cttcaccagt ttgtgggtta cgacctttgc gagctgcgcg ttcgcgaact
     9361 tcaaagttac caaaaccgat taattgaact ttttcgccgt tagctaaagc atcttgaata
     9421 gttgaaaata cagcatctac tgctgcagtt gcatcttttt tagttaaatc agtagctgaa
     9481 gcaacttttt cgattaattc tgctttgttt gccatggata gattcacctc ctccacaaga
     9541 gatatgatag aaatatcatt tagttaaaac tttctgagtg gtccagaagt ttaaaaagaa
     9601 atattgatta acttcaatat tctgttatca cgatatcata tgaaccgctt aatagcaagg
     9661 tttttaccaa ttttcacatg ctttttttag tcatagaaac gtaacaaacg aaactgtctt
     9721 tttcttttga aaaaaaaacg tcgatatggt aaaatgccta ttttctccta cgagggataa
     9781 ttcggatgga cgtcccttca aaagtaaatg cttttctgat ttgattttct aagaaacgtt
     9841 cataagaaaa atgcatcaat tcctcttcat tgacaaaaac gacaaatgta ggtggtttga
     9901 cagcgacttg tgtagcataa aaaatcttca ggcgttttcc tttatctgtt ggtgttggat
     9961 tgattgctac agcatccata atgatatcat tcaacacagc cgaagagata cgaagattct
    10021 ggttcatact tacttgttcg atcatttcag gcagacgttc caaccgttgt ttagtcactg
    10081 cagaaacaaa aacgattgga gcgtaatcaa gataccggaa ttcatcacga atctcttgtt
    10141 cgaaatcacg cattgtattg gtttctttct ttacaagatc ccatttattc acgacgataa
    10201 taattccacg accagcttca tgggcgtaac ccgctactcg cttgtcttgt tcccgaatcc
    10261 cttcttcagc attcagtacc atcaaaacga tatcagaacg gtcaatggca cgcattgcac
    10321 gcatcacgct gtatttttca gtattttcgt atacttttcc gcgtttacgc ataccagctg
    10381 tatctatcat taagaatttc tgaccacttt cagaaacgaa gtgggtgtcg attgcgtctc
    10441 gggtcgttcc ttcaatatcc gaaacaatta cacgttcttc tcctaaaatc gcattgatca
    10501 aagaggattt accaacattt gggcgaccaa tcaaactaaa cttaatcgtg tcgtcgtcct
    10561 cttcttcagt ctcttcagag aaatacttca ctgcttcatc taaaatatca ccaatcccta
    10621 gtccatggct tcctgaaaca ggataaggat cgcctagccc taaggaataa aattcataga
    10681 tatcgtttct catttctgga ttatctactt tattgactgc taaaatcact ggtttattac
    10741 ttctgtataa aattttcgca accatctcat ctgcgtctgt cacgccttcg cgtccgctga
    10801 ctacacaaat gattacatct gcttcttcaa tcgcgatttc tgcttgatgc ttgatctgat
    10861 ccataaaagg ttcatcgcca agatcaattc cgcctgtgtc gatcacgctg aattctcgac
    10921 ctaaccattc accttttgca taaatacgat cacgagttac tccaggagta tcttcgacaa
    10981 tcgagatacg ctcaccagcg atgcggttaa aaatcgtaga cttaccgacg ttcgggcggc
    11041 caacgattgc aattgttgga tttgccatat tatttcctcc tcacaagttt ccaatctcac
    11101 ttagtttaac gaatgcattg ccaactttca agcatagatt gtcaattaaa cgaagtattt
    11161 ttattcctta ttgaaatact aatcgctttt caaaagaaaa actgagacaa aagcagctgc
    11221 tttcatctca gtcacagata caaaatcaat tatttttcag aatcatcggt tgctttttct
    11281 tctacttctt ctttcaacgc atcacctaaa atgtctccca tagtaaatcc agtattttct
    11341 tctggtaatt cataagactc aacatttttt ggttcttctt ctgaagctgg tttttcttct
    11401 aaagctttga tactcaatgc aatacgatgt tcttctggat ggatctctaa tactttcact
    11461 ttcacttcgt caccttcatg aagcacttca tgtggtgtcg caatatgttt atgtgaaatt
    11521 tgagagatat ggactagccc ttctactcca gggaacactt caacaaaggc accgaagctt
    11581 gtcaaacgtt taactgttcc gtctaatact gtgccaactg gagcttttgt atcgatttct
    11641 gaccaaggtc caggctgtgt gtctttgatt gacaaggaaa cacgttcttg ttcaggattg
    11701 atagacaaca ctttgacatt tacatcatca ttgacagcca atacatcact tggttttgct
    11761 acatgactat gtgaaatctc tgagacatgg actagaccgt caattccgcc taggtcgaca
    11821 aatgcgccaa aatcagtaag acgtgcaaca cgtccactga gaacatctcc ctcatggata
    11881 gttgaaagaa tttctttttt cttttcttct ctttcgtttt ccactaccgc tttatgcgat
    11941 aagatcaaac gattttctga tggttcgatt tcgatgattt taaagctcaa tgttttgcct
    12001 ttatagtctg aaaagtctgc aacaaaatga tcttccacca ttgatgcagg gacaaaacca
    12061 cgtacaccga cgtcaacgac taaaccgcct ttgacaacat ttgtaacagg tgcttcgatg
    12121 accttgccct cttggaaatc tctttcgata tcttcccaaa cttttttagc atctaaacgg
    12181 cgttttgaaa gtagatagct gccgttttct ttatctttgc cgatcgtact gataacgact
    12241 aaatctaata catcaccgac ttttactact tcgctgatat cttctaccgg caaagttgat
    12301 aattcttttg ccggaacgac tccttcaact ccagcccctt cgattccgac aatcacttgt
    12361 ttgtcttcaa tgactaaaac ttcgccctta acaacatcgc caacttttac ttcttgtacg
    12421 cttttcattg cgtcttccat tgactggttg ttctcttgat tttgatcaaa ttctgtcata
    12481 acacttgtcc tcctaaccaa cattctgccg taagtacggt actgttttta gtttaattga
    12541 ttattcaaaa aaaataaagc gatttcgttc gttttccttg aaaaaacaat tgtttttcat
    12601 tttttttctt aatttaaaaa agaagataac cttttttcaa aacaacagct tttattgctg
    12661 caacgacttc tggaatcgat ttgccagtcg tatcgatacg aacagcatcc tctgcttgct
    12721 tcagcggaga gacgtccctt gttgaatcat aatggtctct ttcctgtatc tctttcgtca
    12781 gtgtttcaag atcagtcgga attccttttt cttggttctc tttgaaacgt ctttctgcac
    12841 gctcacttac gcttgctact aaaaagattt tcacttctgc attcggtaat acagctgtcc
    12901 cgatgtctct tccgtccatg acaacgccac cgcgttcccc tatttttcgt tggacagcaa
    12961 ctaattcttc tctgactttt ccatgtgcag agacttcaga aacagctttt gtgacatctg
    13021 gttgacggat ttctaaagtc acatcttttg atgctatgaa tacatgctgt ccatcttctt
    13081 gttgcgaaaa agagatagga tactttttga tcagcgaaac tagcccttct tcatctgaaa
    13141 aagatacatt gttcgtaata gctaaataag ttactgcgcg atacatggca ccggtatctg
    13201 tataaatata attcaattct tttgctaata tcttggcaac ggtacttttc ccagatgaag
    13261 caggcccgtc gattgcaata ctgatttgtg tcatgatata actccttttt ctcagaaaaa
    13321 aagccgcaaa gcgcggctat tattatttaa ttcttaattc ttgaccaggg taaagcataa
    13381 agttgtttgg atctaagcca ttcaattcaa acaattgatc agtggtgatc cctgcacgct
    13441 cagccacttg ttttggacct tcgcctgctt gaacagtcgt tgttgaaccg gctgcagctg
    13501 atgaagaagg tgttgtttct gctgcattgc tgcttgaatc ccctgcttga taagttgcct
    13561 cacttgagga agtcggtgtt gtctctgctg caatactgct ttctgacgtt acacctgtat
    13621 cttgagacac agtagattct tccgcgattg tactagattc tactgttgaa gtctcagttg
    13681 actcctcttt tgttgtactt gtagaacttt ctactactga tgtcgaagtt tcagaagaag
    13741 ttgctgctgt tgcattgttg cttgatccat ttctgatcca gaaataagca cctgctggaa
    13801 tagcgataca taagaccagt aaaatcaaaa atagcgaaag aaataatgta tttcctttct
    13861 tttgttgtct ctgagaactt cttgatgaaa cttcatcatc tgtatcgtag attggttgtt
    13921 cccatggttc ttgtgtttcg ttattttctg tagattgatg tctatctttt ctgctcactg
    13981 ttttacctcc taaactctat cgtgtgtatt ataccatagg aaaaagtgtc ttgtcctaaa
    14041 aaatcaatgt tccatgtttt ttttaaataa atttagtaaa atcgttcccc aatgaagttg
    14101 ttcagtctta gaaaaaagct tcctctttgg cagaagttct gcttttgctc catcaatatc
    14161 acaacaattc tgcggctttt cggagagttt ttcgccaaaa taagctaaga tgaattttct
    14221 gcggcagttt tcttcattaa tatagcgaag catctgctgc aggcggaatt ctttttcttt
    14281 ttcctgacgt ttgagccgtt ccacccaatt ttctggtttt tcagactgct ggatcagctc
    14341 catccatttt ttttgcagct catcaaaggg agcttgctct gtggcatatt ccaaataaag
    14401 ctcaaaactt tgtcgctgtt ctctagaaag ttgattaaag aaataatgga tacgttcatc
    14461 cccactttga taaaaaagaa ttgctgcact ttcttcctga tctctgcctg ctcgaccgat
    14521 ttcttgtaca tagttttcta gactgtctgg caaatcataa tggaccacat aacggatatc
    14581 agatttatcg atccccatac caaatgcatt cgtagcaatg agaaactgca gctgattttt
    14641 tacaaactgc tgttgaagtt gtcttctttg agctgcatca agaccaccgt gatagtatcc
    14701 aactgtaaaa cgttccctga ataaatgata caatcgttcg acttcttttt ttgttgcaca
    14761 ataaatgatt gccgctcctt gtgctctttc catgaagtgt tcaagttctt gttctttttg
    14821 ctgcgttttc cgaacaaaaa gcgagatatt ttgccgattg actgattgtc tgatctcttt
    14881 tggtggtcga tcaaatagta catgacgtat atctcttgct actaaatctg ttgctgtcgc
    14941 cgttagtgcc agtgtgaccg ggtttcctaa aagctttcgg atttttccta actgttgata
    15001 ttctggacgg aaatcaactc cccattgaga cacgcaatga gcctcatcta ctacatataa
    15061 cgcaatattt tgttttttca gatgctctaa aagagaagga ttagtcaaca tttcgggact
    15121 caaaaacaaa aatttatatt gcgatagatg acggaggacg tatcttcttt cagattgcga
    15181 aagtaaacta ttgaaagcag ctactcgttt ctcccctcgt ttttgtaatt gcgtcacttg
    15241 atcttccatt agagaaagca gcggtgacac gatgatgacc agaccttcca ttaaataccc
    15301 cgtcaattga tagcaaaggc tttttcccgt tcctgtaggc aaaatagcga gagtatcttc
    15361 tccatcaagc aacgcctgaa taatttcttc ttggccggga cgaaatgaat caaatccaaa
    15421 atattttttt aattcattta ttaacattct gtatcgcttc ctttctcaat agatagattt
    15481 gatacaaacg aaattctcca taatctaatt gtccatctac attccattcg ctaaagcgcc
    15541 actctcgcac ggaatcctta tttggttcca aacgttcgat tgtttctgca gagagaatcc
    15601 actcgtatgg aaaatcatca aaaaacaagg cccactcaat aagatgatct gttactgttc
    15661 ctctttttaa atgacggatt gccatgatct ggtcaattgt ctgaccattc ataaacatct
    15721 gcttggtgat catcatgctt tgattgaaat tttgctgtaa taatgaatcg atcaaagcgt
    15781 gccaaagcga atctggccgt ttttcgattt gtgctaacaa aaggtggata catctgcttt
    15841 gttgcagata aaccgctgac tcatcattgt tttttgccag ctgataagga agcagccctg
    15901 ttcgctcatt tccagataat tggttagcta aaaaatctgc tgcttcttct ggtatctccg
    15961 aaaacagctg caccaaactc tcatacgcag tatcaatcaa aatttcacgt ggcaattggc
    16021 tttcactaag ccattttttt agttggaaag tataaaaagg acttgtctct gctggaagat
    16081 agtcttgaat acccgttgcc agattagaaa ttacttgaac agcaaattta atgagccgcc
    16141 aactagtttc ccctgttctg ccatagcggt caaaacgcaa accagtatgt tctatttgat
    16201 gttcggacaa catatcagcc cctgcaggcg ttagctttgc ttcattttca tttatttcga
    16261 tccaaccttg ctgcgcaatt ttttgcaaaa tttgataaaa cttatcctgc ttcaattctg
    16321 gaaaactgtt atggataaac aaaagttcgt gggtaaatcc ataaataagt actgaagtcg
    16381 ttcgttttcc cacaaggagt tggtaaagag aactaatccg cagcttgtgt cctgatgaaa
    16441 atagcgataa aataaaaaca atcatattat tctccttaag ttaggatggt tagaaatgtc
    16501 actactatgt aaacttgtac ctgaacgctg tattgcatgc ggtctttgtc aaatcgaagc
    16561 gccagatatt ttcgattatg atgaagaagg aatcgtttta tttgcccaag aaccagaggc
    16621 tcatcaacag ttcgtgatgc cggaagaaga aacatatgta aaaaaagcgt atcaaaaatg
    16681 tccagttcga gcgattttat tagaaaataa aatataaata taaacgaaac tttaaaaacg
    16741 tacactaagt tctctaaact tgaaaataag ccgggatctg tttctcttgt tccgtgaaat
    16801 cccgacttat tttgaaagat tcatttgcta tctatagtta attgactagt tttttcacgg
    16861 accctatagg acccatttat attatttcaa ctttttcagc cagttttcca atgtattgac
    16921 gatcacagtt tgctggtctg cgttagaaat ttctgcctct ccatctcctt tttgctcacc
    16981 atagctgcca aaacctccat gatttccgcc attgattgat acatactctg ttctttccgg
    17041 taaatactgc ttagcttctt gataagcttc ctgattcaat actttatctt ttgtcgccgt
    17101 gatcgataaa acaggaacag ctgattctgt caatgttcct tttttgtcgg gataacttgc
    17161 catgaagaat acccctttta aatgtttgtc tgaatgattc ttattgacat aacgacttgc
    17221 cattacgcca cctaatgaat ggccaccgat cacataatcg gaatttggaa aatcttcttt
    17281 gaccttatcc gctttgtttc cgcccatcac tgctagatca agtggcattt tgacaatagc
    17341 gactgaaaag ccgttttttg ctaaatcttg cgcccaaata ctataacttt ctggctctac
    17401 gagagcacca ggataaaaaa taagtaatgg agactttcca tgattctttt tctctccttc
    17461 aaaaaataag taatcttctt tgttttttcc ttcttttacc aacacttgcg cttctgacga
    17521 tggttcgtac gtattttgct gtatatagta ataaccggct ccaccgagta atcctaaaat
    17581 gatgactaag ccaattagta ttcgtctaaa tattttcact ttctcccacc ttttctatct
    17641 gagtgacccc tttttcttaa tcaagtatga ttatacctta aaaaaataag agagaaatgc
    17701 aaactttcca gcatcaaata aaaaaagacg gaatatccat ttgaatatcc gccc
//
LOCUS       DACGEU010000057        17152 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.057, whole genome shotgun sequence.
ACCESSION   DACGEU010000057 DACGEU010000000
VERSION     DACGEU010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17152)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17152)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17152
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.057"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(734..1912)
                     /locus_tag="IXR40_001836"
                     /pseudo
     CDS             complement(734..1912)
                     /locus_tag="IXR40_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEfm2 family transposase"
     gene            1942..2352
                     /locus_tag="IXR40_001837"
     CDS             1942..2352
                     /locus_tag="IXR40_001837"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361675.1"
                     /translation="MVTLFYRRDFLFSIYTKYFTLSSNIKTSTKLICKLFKLDKISNI
                     DDVKSKILTRKVSEPVKLTAQDKKNGIVLYGDDAKYNYNWDTSSEAEVLSIPTTDTSG
                     EKVTFKINFITAISKLEYGKQKKRDNNDQYLPKK"
     gene            2433..3053
                     /locus_tag="IXR40_001838"
     CDS             2433..3053
                     /locus_tag="IXR40_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361676.1"
                     /translation="MNINRVIKLIGAKNINKVRSEFIFPEDFFNWFFYQFSECKRLLG
                     ENYYLKGIGGFMGNVADEQNIIKGISEQTSELTVTKAFISNGESLKNVTARIRKENEV
                     DIVFGIDHECNSVIYVTQSANLILFENGCKDDFMVVYLYDILIPKLRSLYMSSESIFV
                     SEQKGSFSKKIGIEVIESIMCHNHITLEELEILIGQKNNNTKIQVS"
     gene            3754..4038
                     /locus_tag="IXR40_001839"
     CDS             3754..4038
                     /locus_tag="IXR40_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAQ4361677.1"
                     /translation="MFSFAFYMVWLQREVPTHIQGRLMSTITTITMVASPLGLALFGA
                     LFDWQTTQPRLRDSLIFLEIQLENLHFLYTFLAAFFIPVNYTSLINKKEG"
     gene            4041..4958
                     /locus_tag="IXR40_001840"
     CDS             4041..4958
                     /locus_tag="IXR40_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAQ4361678.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            4951..5733
                     /locus_tag="IXR40_001841"
     CDS             4951..5733
                     /locus_tag="IXR40_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAQ4361679.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMIAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LILATLSVPVALTFITRSTSVSLLLSFLYIMGTAFVPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            5734..6414
                     /locus_tag="IXR40_001842"
     CDS             5734..6414
                     /locus_tag="IXR40_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4361680.1"
                     /translation="MFLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            6407..7303
                     /locus_tag="IXR40_001843"
     CDS             6407..7303
                     /locus_tag="IXR40_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAQ4361681.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWVDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDSFIRLTVANPIKPGAQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            7498..9147
                     /locus_tag="IXR40_001844"
     CDS             7498..9147
                     /locus_tag="IXR40_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HAQ4361682.1"
                     /translation="MGQREFIVLIIIAVVILLVVLDIFSRLKVKETVRSNWGKIPYQP
                     RFDKEESLKDAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDYQLEKLIAFYQENPQLRERIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGVGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKMTTPLQKELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAVLNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLNYPKSIVEQAQKESLLFDEQRQWYPFD"
     gene            9741..10676
                     /locus_tag="IXR40_001845"
     CDS             9741..10676
                     /locus_tag="IXR40_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4361683.1"
                     /translation="MANALEINNLKKIYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDKDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYDTKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            10669..11439
                     /locus_tag="IXR40_001846"
     CDS             10669..11439
                     /locus_tag="IXR40_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4361684.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMISGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            11855..12838
                     /locus_tag="IXR40_001847"
     CDS             11855..12838
                     /locus_tag="IXR40_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HAQ4361685.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKDPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILETFEKEHPTLFSEQ"
     gene            13285..14322
                     /locus_tag="IXR40_001848"
     CDS             13285..14322
                     /locus_tag="IXR40_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HAQ4361686.1"
                     /translation="MSEKELMKVVGFYEGLPIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGSGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHML
                     GKVVVSGPFNG"
     gene            complement(14411..14734)
                     /locus_tag="IXR40_001849"
     CDS             complement(14411..14734)
                     /locus_tag="IXR40_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HAQ4361687.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRVLPFILLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLAGILSLS
                     LIRLL"
     gene            complement(14721..15428)
                     /locus_tag="IXR40_001850"
     CDS             complement(14721..15428)
                     /locus_tag="IXR40_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HAQ4361688.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLVYAGSAQFITVSMLASHSPLLSIVFSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVIVV
                     VTLIGCGLGVWIKHAFF"
     gene            15514..15855
                     /locus_tag="IXR40_001851"
     CDS             15514..15855
                     /locus_tag="IXR40_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
                     /protein_id="HAQ4361689.1"
                     /translation="MVGLKRKELAGRRFTRIVSVGGGAKNLAWLQIQADIFDATVYCL
                     SVEEGPALGATMIAALGLGWFDTPESCCQNFIQYTDAVEPLLQNVEKYHKIYQQCRKI
                     YPATKEICHDL"
     gene            complement(16026..16874)
                     /locus_tag="IXR40_001852"
     CDS             complement(16026..16874)
                     /locus_tag="IXR40_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361690.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPHFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKLKKR"
BASE COUNT         5462 a         2915 c         3573 g         5202 t
ORIGIN      
        1 taatgaaaaa cgagaaggaa gatgacttta aagtagttta gtatgaaggt cgattgataa
       61 aacgatgtgg attaatgcta aataatgagt aatttttcaa taatacaaaa actgtgtaca
      121 gtattagaag tagagaaacg ctagcgtcga aaaaaagata tttttcgtga aaagtaatag
      181 gggctaaaaa gaaagtatac aatttattta tgtttctaag catataaaaa agagcgttga
      241 aaggaatatt tccccttcaa cgcttctttt ttagaagatt ttaatgacca tctcaacttc
      301 attttcaggt ttaggtaatt catggaagct tgtgtttatc gtgcttaatt gatcaactaa
      361 ccatgtttta ctttttgact cgtagacaaa tctaaaatta atatcattgt tctcgtgttg
      421 aagaggtttc tccaaataat ctggtgaata ttcatagtca acgtaacctg ctaatacaaa
      481 agaaagcagt ccattattta gtgtcagatt taacggatgg tcgtaagctt ttattttttt
      541 aatgtcatat tgtacatctt atgaagactt aatgactact tgtagtcaat agatttaaag
      601 tatttatttt ctcatttatg tatcaagaat aaatactgat ataataaaaa ttatatcaat
      661 gttttgatga agtaatttgg agggagcgtc aataattttg tgtaaataac tcgtccttct
      721 gcaaaataat gggttactca gtaaacattg aagctaatgt atccgtcact tgttggaagc
      781 ctttatggct tctatttaag aatttttgat tgtatgtatc aaagatggat actaggaaac
      841 gctctagtga ttcttcattt tgaaactgct cttttctgcg gctgtatttc ttgatttgtt
      901 tcttgaaaga ttcgattaaa ttagttgagt aaatgcttcg gcggatacca ggcggaaact
      961 cataaaaagt caataaatct tgatttttta tcagtgactg cgtcacttta ggataagttt
     1021 tttgctactt ctcaatcata ctccctaaaa aggtatttgc ctcttccttt gagctagctt
     1081 gataaacagc cttaaaatca tcacagattt cttttcgatc tttgacacgt actttatgag
     1141 caatattacg ggaaacgtga acacagcaat gttggtattt agctttagga taaatctggt
     1201 gaatcgtatc tttcatgcct tttaagccat cggtaataaa cagtaagaca tcatgaaccc
     1261 ctctggagta aatgtcctgt aacaactcat tccaaacgta ggtcgattca gtcggagcaa
     1321 tcgcataact tagtacttct ttagtgccgt cttctcgtat accaatggca atatagattg
     1381 cttctttgga gacggtttgc cgttttaaag gaatataagt agcatccatg aaaatagcga
     1441 catacttatc atttagagtt ctaactttaa atgcatttac ttcttcagtc agcactttag
     1501 tcatgttgga catggtttgg ggcgtgtagt gatgcccata cattttctca atcaagtctg
     1561 cgatttccga catggtaata ccttttcgga agaggtgaat gacggtctcc tctaagatat
     1621 cattcgtccg tctataagca ggaacagtct gttgcttgaa ctcgccgttg cggtcgcgcg
     1681 gaatctggag atgaagttcc ccgtactcgg tcttgaccgt acggtcatag gagccgttac
     1741 gagaattccc cgtgttaaaa ccaatgcgat cgtacttttc gtaatcgagg aaagccgtta
     1801 actccgtttt gagaagcgta ttgacagctt tttccaaatg gacacggaat aattcattca
     1861 aatcgccttt gttcgctaga gtctttagaa tttctgtagt aaaatcgttc atatggaagt
     1921 cctcttttct gtgaatgtgt tgtggtaact ctattctaca gaagggactt ccttttttct
     1981 atttacacaa aatattttac actctcgtca aatataaaaa ctagtacgaa attaatttgt
     2041 aaattattta agcttgataa aataagcaat atcgatgatg taaagtccaa gatattaaca
     2101 agaaaagtaa gcgaaccagt aaagctaacg gcacaagata aaaaaaatgg aattgttctt
     2161 tatggtgatg atgcaaagta taactataat tgggatacct cctcagaagc tgaggtatta
     2221 agtattccta ctaccgatac ttcaggggaa aaagtcacct ttaaaataaa ttttataacg
     2281 gcaatttcta agttggagta tgggaagcaa aaaaagagag ataacaatga tcaatatcta
     2341 cctaaaaaat aacgaattaa tgatgcatat gttaaagttg tttttttgaa ttaaacaact
     2401 caatttattc agttatatgt tcatcgcagc aagtgaacat taatcgagtt ataaaattaa
     2461 taggagctaa aaatataaat aaagttcgat cagaatttat ttttccagaa gattttttta
     2521 actggttttt ttatcaattc agtgaatgca agcgactctt aggtgagaat tattacttaa
     2581 aaggaatcgg cggatttatg gggaatgtgg ctgatgaaca aaatattata aaaggaatat
     2641 ctgaacaaac atcagagctt acagtaacta aagcatttat aagtaatggt gaaagtttga
     2701 aaaatgtaac tgcgcgaatt agaaaagaaa atgaagtaga cattgttttt ggaattgacc
     2761 atgaatgtaa ttcagtgata tatgtaacac aatcagcaaa tttaattctt tttgagaatg
     2821 gttgcaagga cgattttatg gtggtctatt tgtacgatat actaattcca aaacttcgtt
     2881 ccttatatat gtcttctgaa agtatttttg tgagtgaaca aaagggatct ttctcgaaaa
     2941 aaataggtat tgaagtaatt gaatcgatta tgtgtcataa tcatattacg ctagaagaat
     3001 tagaaatttt gatagggcaa aaaaataata acacgaaaat acaagtttct tagaaatcat
     3061 tttttattga gatatctaga taaatgattt attcttcaat caaccaactc gccaagctga
     3121 ggtaatgttt tgaggtaatg ataacataca actttttata ccctagtaaa actctataaa
     3181 caaagactta ttaatttcgc atgaaataca ttcctgtaaa atgcaataaa atagagtttt
     3241 gtttaaccag gtcttaagaa agcccgtaaa gcttcacagt tctcaaaacg ttaattgcga
     3301 ttatcgttcg agttcacgag ttacgagaat cgtactgggc gaagcaatgc tgagcgcagt
     3361 taccttaatc ctaacttttc tggcactttc cacaatttgg aaagtgcctt ttttgtgttt
     3421 ttagctatgt taataggtag gattcttggt ctataatatc attcgatcta taaacaaacg
     3481 ggaaaaagat aaagtatcat caaacaatat tatttatccg cttctgaggt tgtgacagaa
     3541 gtggtcagct tcaagaaata agaaggaatt tacaaaaatt gcttctcatg tttgataaat
     3601 attgtgactt gtgaccgagg agttggcagg agaacaccgt ttattcggaa gaagggattg
     3661 tgaaaagtct tttgtcataa cctcttattt ggtagctaat tgtaaatccc aaacggcatg
     3721 tattattttt cataagtccg tttttaagga ttaatgtttt cttttgcttt ttatatggtc
     3781 tggcttcagc gagaagttcc aacgcatata caaggacgtc tgatgtcaac gataacaacg
     3841 attaccatgg tggccagtcc acttggatta gcactgtttg gtgcgctctt tgattggcag
     3901 acaactcaac cacgtctgcg agacagtctg atttttcttg aaattcaatt ggaaaattta
     3961 cactttcttt atacatttct ggctgctttc tttatacccg tcaactatac ttcacttatc
     4021 aataagaaag aaggataagt atggattttg gaaatgaaac ggtcttgaaa gcaactggta
     4081 taaccaaaaa atacggtgct gccaaagcat tagataaagt atcgatcgaa atcaaacgtg
     4141 gaatgatcta tggtttgatt ggggagaatg gagcgggtaa gtctaccttt atgagaacta
     4201 ttatgggttt gatctcgatt gatgaaggtt cgatcgaatt atttggaacg acggatttgc
     4261 aggcagcaag acgacgtatg ggtcaatcga ttgaaacccc tgctctttat ccagaattaa
     4321 ctgcaagaga taacctacgt atccaagcag cgaacggcgg tgtgtcggat agagaaatcg
     4381 aagacctgct gaaaatgatg cgattggaaa atacagggaa aaagaaagca aagaatttct
     4441 ctttaggtat gcgccagcgt ttagctattg caaatgcact gatcacgaat ccagaatttt
     4501 tgattttgga tgaaccgacg aatgggatgg atccagcagg gatggcagaa atgcgagaaa
     4561 tcatccaacg tttggtaaaa gaacggggca tcaccgtctt gctttctagc cacttgctag
     4621 atgaattgtc acagatcgcc actcactacg gtattttgca tgaaggacac ttgatcaaag
     4681 aattatcgaa agaagaattg gcacaagaat ctcgtcaatt tataaaaatt gacacttcgg
     4741 cgacggaaca agcagtaacg gttctcgact ctcttggtta tagggattat tttgtccaat
     4801 ctagccgtgt tatccagctt tttgaaggaa ttgaccaagt agcagccatc aatcaagcat
     4861 tggtagaggc aaaagttcct gtggatggta tccacctagt tgggcaaaaa ctggaagatt
     4921 atttcttaca attaactgga ggcaatccac atgtttaatc tattaactgc tgaaaaaata
     4981 aaagtatgga agagccgtaa aatgtgggtc tcactaggac tgatggtcgt acttccgctt
     5041 ttttattctt ggaacgaatg gtatatgcat acaaaatacg gcaatgaatt aaaccaagca
     5101 acggatacag tcatcaacgg tgcaacaggg attttaatgg tggaaaaaat ggctgcatgg
     5161 attcttctgg ctttcgcagc atttgcgtgc ttttatattg gggaagaatt tcaaaacggt
     5221 acgattcgca atacgttatc tttaggacgg aatcgaatga cttattatgt gtcgaaactt
     5281 ctcgttacgc ttttgatcac aacacttggc gtggttttga ttacggggct agccatgatt
     5341 gcttacacac ttgctttcgg atttggtgaa gttgagggaa tcaaaaacta tggaaattat
     5401 gttctaaaag tatttcctgt attgcttctg ctgatattag cgacattatc tgttccagtg
     5461 gctttgacat tcatcactag aagtaccagt gtcagtttgc ttctttcttt tctttatatc
     5521 atgggaacgg ccttcgttcc cggtgttttc gcaaaaatca aaggcttgga atttctaacg
     5581 gagtggttta cggaaacgtg gctcatgtat acggactttg cgcaacaagc aacttattcg
     5641 caagcaccga aaatgattct ggtcagtcta gtaacaatcg tggtatcatc agctctagga
     5701 atgtttattt tccaaaaatc tgacattaag taggtgttcc tgctggaaac tattttgatt
     5761 atcgaagacg atgaagctgt tcattcttta ctggaggagg ttcttgaaca gagatacaaa
     5821 cttcttgatg cttattcagg tacggaagga aaattattgt taagcacata tcctgtcgat
     5881 ttgatccttc tagatctcat gcttccaggg ctttcaggtg aagcattgtt agcagaaatc
     5941 cgacagacat cgaatgttcc gatcatcgtt ctttcagcaa aaagcgatca aagagataaa
     6001 gtttccttgt tggcagcagg agcggatgac tatgtgacga aaccatttga tatcgaagaa
     6061 ctgttgttac gaatcggcat ccaacttcgt catcagactt ctgtccaagt aaaagatctg
     6121 tcgcaacgca tctattacaa ggaaatctta ctggacaaag agtcgaggga tgtaaatgtg
     6181 aatggtgtgg ctgtccattt gacaggaaga gaattcgatc tgctgaagct ttttttagaa
     6241 catccgaaaa aagtattttc gcgagcaaat ctttatgaaa cagtttggca agaaccatat
     6301 tttgatagtg agaaaacagt gaatatgcat atttccaatc ttcgagggaa actagcaaag
     6361 gcacatgctg tgtatattca tacggtgtgg ggagtggggt ttagatttga ttaagtggct
     6421 gttgcttctc gttgttatct ttatgggaag ttttattttc ttcctgcaaa gggaaatcaa
     6481 gagattaact aagaaaatcg ccactctttc tgaacgacaa gaatatggtg gtcgtctttc
     6541 agtcgaattt cgagaaaaga atctaatgga cctagtagat gcactgaata catgggtgga
     6601 tgaaaatgaa caaaaaggac aagcatttca agaaatggaa gaaaacatca gactatcgat
     6661 cgtcggcctt tctcatgatc tcagaactcc tttgactgct attaacggtt atgtacaatt
     6721 actggaacag gtagaggata cggagaaacg ggagaagtat ttaacgatca tcaaacaatc
     6781 tgttgcaaga ttactcagta tgacggatca gttttatgat cttgctcgaa tagagacgaa
     6841 gcaaaaagaa atggatctcc atacgctttc tttttctaaa gaggtggaag aagtattttt
     6901 ctctttttat gaacaatttt ctgagaaaaa tatcgaggta gcgttcgctg aacactcgat
     6961 aaatacaact gtattagcag atccgctcat gttgctgcga gtgctgcaaa atatcataca
     7021 gaatttattg cgttatgcag atggacaagc aaaggtgaca ttttcaaaag aggattcatt
     7081 cattcgatta acagtggcca atcctatcaa accaggagcg caaacctctg ttgaaaaagt
     7141 cttccagcgt ttttataccg aaaataccag ccgcacaaat acggaatcta gcggaatcgg
     7201 gctttacctg tcaaaaaaat tggtggaagg aatgggagga gagatgaccg ctagattaga
     7261 cgggggcatc ttctccatct ccgtcaagtt gcggagggtt taattggctc taatttacct
     7321 gaagtgaatg acaaaaaatt gtatctcgtt ttaaagacat cttctttttt ggaaggtgtt
     7381 tttattttgg tgtgattgat acgaattagg taacgaagac agttattttt gtaccccctt
     7441 ttcaaatagc gcaacagtgc tatactaaaa ctaacaaatc aaggaacgga gagggatatg
     7501 ggccaaagag aatttatcgt tttaattatt attgcagttg ttattttatt agttgtttta
     7561 gacatttttt cacgtttgaa agtaaaggaa acagttcgta gtaattgggg aaaaattcct
     7621 tatcaaccga gatttgataa agaagaaagt ttgaaggatg cgtggctcac ggagaaaaaa
     7681 ttccgttcat gggatagtga aatcgacgat cttacttggt atgacttgga tatgttcgaa
     7741 gtatttgaag ggatcaacag tacctattct agtgtaggtt cagaagcgtt gtatcagcgt
     7801 ttacgtagct ttgattttgg agaagattat cagttagaaa aactaattgc tttttatcag
     7861 gaaaatcctc aactgagaga aagaatccaa tatcaattcg ctcgtttagg aaaaaaagat
     7921 cataattttg caaaacaata tctagcggat ggaaaaagta aaaagattgg acgcgtaggt
     7981 ttatttattt ttcttggctt gcttccgctg gtgggtgtag gtttgcttct tttagggcaa
     8041 gtactaggaa tctatctagc aatcggtggc ttagtattca atacggtcta ttatctagtg
     8101 aagaaacaaa cactagaaac agagctgaat agcatgagtt atttggtttc aacgatttca
     8161 gccgccaatc agttagcaaa aatgactaca ccacttcaaa aagagctgaa acagcaaact
     8221 aaaccattaa gagacatccc taaattaggt ttttcatttc gaatgaagag cgggagtgaa
     8281 gcagaattga tttttgaata tgtcaacatc atgttcatgc tgccatttat ctcctatcat
     8341 ttcgttctca ctaaattaga aaagcattca actgaagcca tcaagctgtg ggaattgctg
     8401 ggagaattgg aagttgcagc agccgttttg aattatcgca cctatatgcc gatcacttgc
     8461 cgaccagagt ttactgaggg cggtgtgaca gcgaaagata tctatcatcc attgttaaaa
     8521 gaagcggtag ttaatccagt caactggcag aagaatacat tagtcacggg ttccaatgca
     8581 tcaggaaaat ctacgtatgt caaaagtata gccatcagct gtattctagc acagacgatc
     8641 caaacagcga ttgcagaaca gtttaccctg caacctggac atgtgttgac ttccatggca
     8701 atcgaagatg atttatttga aggcgacagt tattttgttt cagaaatcaa atcgatcaaa
     8761 cgtttgctgg accaagtggc ttccaaagaa cgctgctact gcttcgtaga tgagatttta
     8821 aaaggaacaa atacgatcga acggattgct tcttccgctt cagtcgttcg gtggcttgcg
     8881 gagtatccat ctttagcatt tgtcgccaca catgatatcg aattgacaga gattttaaag
     8941 aattattgtg agaatgtcca ctttgaagaa caagtaacag aaggaaaagg aatcagtttt
     9001 gatttcaaat taaaagaagg accttcaagg acccgaaatg cgattgcctt gctgaaagtt
     9061 ttgaattatc ctaaatccat agttgaacag gcccaaaaag aaagtttgtt gttcgatgaa
     9121 cagcgtcagt ggtatccgtt tgattaactt tatcaaacga agcatgatgc gtgggtccaa
     9181 aaagacgatt atcaaaagaa gtacattgat gccaaaaaag tggcagaatt caatgggaac
     9241 gagtctgctg tccagatgat cttggaagat ttagcaaaag acgatacaaa ataaaccacg
     9301 ctgtcttcct tctagcagct tttatcgaaa aaacttagca tcagcgacga gacgcacgtt
     9361 ccatggcaaa gttctccgta aaacaaacag cgaaaacaga aattgaaaat aactatttcc
     9421 attttattta tttcggttaa aataaaagaa aaaagctttc gataaaagga cggaggaaag
     9481 cttaacatga ataaaaaaga caagaacctc agttataagg atcttctata tgtcatcgta
     9541 gtagttgctg tcggtacttt tatgatttta aaagttccag agttgtttag atagttattc
     9601 tatcgaagat gatcatgaac tagaaaacac atctcctctt tgttagcagg tgtgtttttg
     9661 tgtggaagcc aagttgtttt ttcatctgct gtattccatg atacaattaa gaatcatgtc
     9721 tataaggaga taggaaataa atggcaaatg cgcttgaaat aaataatttg aaaaagatct
     9781 atggaagtgg ggtcgaagca ttgcggggaa tcgatctttc ggtgaaagaa ggagatttct
     9841 atgcgctatt agggccaaat ggagctggga agtctacaac gatcgggatt attacttctt
     9901 tagtcaataa aacatctgga aaagtgaatg tcttcggtta tgatctggac aaggatctag
     9961 ttcgagcaaa gcaacagatt ggattggttc cacaagagtt caattttaac ccttttgaaa
    10021 cggtccagca aatcgtcgtg aatcaagcag gctactacgg tgtctctcgc aaagaagcga
    10081 tgaaacgcag cgaaaaatat ttgaagcagt ccaatctttg ggaaaagaga aatgtccgtg
    10141 cacgtatgct ttccggggga atgaagcgaa gactgatgat tgctagggca ttgatgcatg
    10201 aaccacgttt gctgatcttg gatgaaccaa cagcaggagt tgacatcgag ttgagacgcg
    10261 agatgtggga gtttctacga gaattgaacg aaaatggtac aacgatcatt ttgacgacgc
    10321 attatctaga agaagctgaa atgctttgtc gcaacatcgg aatcatccaa tcgggtgaac
    10381 tgatcgagaa tacaagtatg aaagagcttc tgtcaaaact gcaatttgaa acatttatct
    10441 ttgatttagc gccatatgat accaaacctg tgattgaagg atatgcttgt acatttgaag
    10501 atgagcagac aatcgctgtc gaagttgaac gaaatcaagg ggtgaacgga atcttcgatc
    10561 agcttacaag acaaggaatc aaagttcttt ctatgaggaa taagtcgaat cgtttagaag
    10621 aactgttctt gaaaatcaca gaagaaaata atcatacgga ggagaaaaat gtttaatctt
    10681 tattttactg cattaaaaag tttagctatc aaggaaacga accgctattt gcgtatatgg
    10741 gtccaaacac tggttccgcc agtgatcacg acatccttgt attttgttat tttcggaaaa
    10801 atgatcggtg ggcggatcgg tgacatgggt ggtttttcat atatggaatt catcgttcct
    10861 ggtttgatta tgatgtctgc tatcactagt tcgtatgcca atgtttcttc gtccttcttc
    10921 tctcaaaaat ttcagaaaaa tatcgaagaa atcttggtag cacctgttcc tacgcatgtg
    10981 attatttggg gctttgtgat tggtggtgtg ggtcgcagta ttctcgtcgg ctctctcgta
    11041 acgatcattt ccttgttctt tgtaccactt catgtgtatt catggttcat ggtcatcatt
    11101 acattattga tgacggcaat cttgttttca ttagcaggac tgctcaacgg gatttttgct
    11161 cagtcttatg atgatgtatc gatcgtgcct acatttgtct tgcagccgtt aacttatcta
    11221 ggtggcgttt tctatgccat ctctatgtta ccgccctttt ggcaagctgt ttcaaaagtc
    11281 aatccgatcg tttatatgat ctccggtttc cgttacggat tccttggaac gatcgatgtg
    11341 ccagtagcaa catcgatgat cgtacttgtg ttattcatcg ttgttttgta cgccgttact
    11401 tggtatttga tcaataaagg aagaggattg agaagttaga aaagaggttg tgaaatcagc
    11461 gttttgacct gagtattaga gaaacaaacg ggaaaatagt tcctcatatt ttgttgtttt
    11521 ttgagcgaat accgagggtc agctgattga acaccgttta gtggagaggt tgtgaaaaag
    11581 ctgttctgca tcaagtaata agaacagcca aacaaaaata gctcctccta tttttcgttt
    11641 ggttggactt attaccgcag atgcaagctt ttgaacacca tttattccgg aaaatggact
    11701 gtgataagat ttttgtcaca gtcttttttt tgctcaatca gaaacatctt ttaagctgtt
    11761 cactttgctt ctttttttgt ttcctagtat aatgacaatg tttttgagaa agattgcgac
    11821 ttcactgctt gatagaatgg agagtaacaa ataaatgact actaattttt ggaaagagct
    11881 gccaaagcct ttttttgttt tagcaccaat ggaagatgta acagatgttg tatttcgcca
    11941 tgtcgtaaag catgcagcag caccggatgt cttctttact gagtttacaa actcagacag
    12001 tttctgtcat ccagatggaa aagacagtgt acgaggaaga ttaacattta cagaagatga
    12061 acagccgatg gttgcccata tttggggaga caagccagaa ttttttagag aaatgagcat
    12121 tgctatggca gaaatgggct tccaaggaat cgatatcaac atgggctgcc cagtccctaa
    12181 tgtagcagaa cgtggaaaag gcagtggctt gatccttcgt ccagaagtag cggcacaatt
    12241 gattgaagca gctaaagctg gcggtttgcc tgtcagcgtc aagacgcgta tcggctatac
    12301 ggaaatgtct gagatggaag aatggatcag tcacctactt catcaagata tagccaatct
    12361 ttctgtccat ttgcgtacgc gtaaagagat gagtaaagta gatgcacatt gggaagtcat
    12421 tcctaaaatc attgctttac gtgaccaaat cgctccacaa acactaatca cgatcaatgg
    12481 agatatcccc gatcgccaga caggagaaga attggccgag aaatatggcg ttgatggcat
    12541 catgattggc cgagggattt tcaagaatcc ttatgcattt gaaaaagacc cgagggaaca
    12601 tacagaaaaa gaactgatcg gactacttcg tctgcaacta gatctgcaag atcattattc
    12661 agaaatcatc ccgcgttcca tcacaggact acatcgtttc tttaaaatct atatcaaagg
    12721 atttccagga gcaaatgact tgcgagttca gttgatgaat acgaaatcta ctgatgaagt
    12781 acgagagatc ttagagacct ttgaaaaaga acatccaacg cttttcagtg aacaatgatt
    12841 tcttgcttga acaccgtgaa ttagaggtcg tgaaaaagct gtcctgtatc aagtaataag
    12901 aacagccaaa caaaaatagc tcttcatatt ttgtcgtttt ttgagctaat accgagggtc
    12961 agttgattga acaccgttta tatcagaggt tgtgagcctg ccgtttaact ctgagtcaca
    13021 aggagcaatt tcaaaaaaca gcttctcatg tttgatgaat attttgactt gtgaccgaag
    13081 agttggtagg agaacaccgt ttataagagg ttgtgacaaa agtcttgtcg caacctcttt
    13141 tttaaccaaa aaagtgcaaa tagtttactt taagtaagag aataattatg atgaataaaa
    13201 aaggtggaac aaatagcata ctatatatat tgaaatgaac actgtatgga tgctccaact
    13261 tgatgaagct aaggaggaat tcgtatgtca gaaaaggaat taatgaaggt agtcggtttt
    13321 tatgaagggt tgccgatcga tgatccaaaa agctttattg atgaaaaaga acagatacct
    13381 gtacccagtt cacgggatct tctggtaaaa gtcaacgcag tatctgttaa tcctgtcgat
    13441 acgaaacttc gccaagataa cgggataaga aatgctttac gtatcttagg ttttgatgga
    13501 gtcgggaaag ttgttgctgt aggtgacgaa gtgcaaaaat tttctgtcgg cgatcgcgtt
    13561 ttttacgcag gtacaacaac aagagcagga agcaatcaag aataccaact agttgacgaa
    13621 cgtattgtcg ctcttgcacc aaaaaatctt tcagatgaag aagctgcagc cttgccgttg
    13681 acctcattga ccgcttatga attgttattt gaaaaatttg gtctaactcc agaagaaaat
    13741 gccaatcgcg ggaaaaaaat cttagtgatc aacggatccg ggggcgtcgg ttcgattttg
    13801 aatcaactag cgcattgggc tggcctagaa gtctacgcga ctgcaagtcc gaagaatttt
    13861 gaatggctga aaaaaacagg tgtagactat ccaatcgatt atcatcacga cttaagtaaa
    13921 agttttcgtg aattaggaat cgatcaagta gagtatgtcg ctgtattatt cgatattacc
    13981 cgctactttg atcaaatcaa gcaccttgtc cgaccatttg gacatgtggg aacgatcgta
    14041 gggatcaaag agccgttaga tataggtgtt tggaaaaacc aatctatcag cttcgactgg
    14101 gagtatatgt tcgctaaaac agactataac tatgaaatcg aaacgcaagg agaagcttta
    14161 gcgcacattg ctgctttagc aaatgaaggg attatccgca gtacattgag caaggtctat
    14221 tcagatggga tgaatgcgaa gaacttgaaa caagcaacca aagacgtaga aacaggacat
    14281 atgttaggaa aagtcgttgt tagtggtccg ttcaacggat aagcaagaat acgccgattt
    14341 ttttcttatt tgactttgat aaaaacaaga gcgcatgaca gtaatttgcc ataagctctt
    14401 gtttttttat ttataataag cgaatcaacg aaagggaaag aattcctgcc aagacgatca
    14461 ccaataagct ttttgaaaga atagcagcta aaagtgtagg aactgaagcc aaagcatttt
    14521 cgagattgat ctgcggcaga tgtccgatat tttgggtaaa tagactgctg aaccataaag
    14581 cagacataat gacgatcggg acaaaactta aatactcaag caacggttgc ggtaaatcga
    14641 attttttcag taagataaat ggtaggaccc tagaaagcca agttgctaaa gtacaaccta
    14701 aaatagtcag caatgtaaac tcaaaagaag gcatgtttga tccacacccc caatccgcac
    14761 ccaatcagtg ttacaactac aatcactaag ttgcttggga taaaaatcag tccgacatat
    14821 accagaatca aagtgagacc aatcaggatc aactgtaatc gtttagaggt gtttctatca
    14881 gaaatgactt gaagataaag taacccgata aacatagcga cgatggcgaa atccaaacca
    14941 aactttttcg gatcagtaat aaaattccct aaaagtgcgc caacaagaga agaacccacc
    15001 cacgtcaaat aagaaatcca attagctgta ttcatccaac gaaagtttaa cttttgtcca
    15061 gtatagttca atttattcat tcccagtgcg aaactttcat ctgtcagcaa tgtgccaatc
    15121 agcagatttt gaagcagccg atttttcttg aaataaggag caatcgtcat actcatcaga
    15181 atcattcggg aattgactag aaaggtcgag aaaacgatgg aaagcaatgg gctgtgacta
    15241 gcaagcatgc tgactgtgat aaattgggca gaaccagcat agaccagcag ggacatcaac
    15301 gtgacgacta gtggatgaaa tccggcagct ttcccaacga taccaaatgc aagtccaata
    15361 ccgatataac cgaaaacggt aggtaacgtg tctttgatcg cagtttttat atctaacttt
    15421 tcatccaata acaaaactcc tttagcacga cataaatttt cataattgtc gttaaacttg
    15481 tgaatattct aaatttttaa tgagcatttg tcaatggtgg gattgaaacg taaagaacta
    15541 gcgggtcgca gatttacacg tattgtttcg gtgggaggag gcgcgaaaaa tcttgcatgg
    15601 ctacaaatcc aagctgatat tttcgatgca acggtctatt gtttaagtgt ggaggaagga
    15661 cctgcattag gcgcaacaat gattgctgca ctagggttag ggtggttcga cacacctgaa
    15721 agttgttgtc agaattttat ccaatataca gatgcagtgg aacctctctt acaaaatgta
    15781 gaaaagtatc ataaaatcta tcaacaatgc cggaaaatct atccagcaac gaaggaaatt
    15841 tgtcatgact tataaaacaa aacgcgtacc taatagtcaa atgactaata ttgggtacgc
    15901 gttaagtctt ctttacttca tcctttgcat gattcgtgtt tttaaagcaa ggtctgctgt
    15961 atttcttgtg gatttaggat ggttgttatc gtttacttgc tatttttcat tgaaatcgtc
    16021 tttctttacc gtttctttag ttttttatct atttttttct tttggttaga aaattctttt
    16081 tcccgaaagt cttctttcag gatttttata gagtagcgtt ttgaataaga ggcgtcagta
    16141 tgatcgactt ggcagacgaa ccaagagaac atttgccttt tttctgcatg aggtgcttct
    16201 gctaataatt ctttccataa ataataacag tcctctatca gaagaagggt tcgttcatcc
    16261 tcaggctccc aatagaatgt ttcgagagta gcaatcactt cattgatcaa ttcgaatgcg
    16321 ggaagatagg cattttgctg aataagcgat tcaactgctt cttggatgaa ctttcgcatc
    16381 tccatgatga acttcgctgt tttcctgttt ttgtttttct tgataatatg atcgtattta
    16441 tggatgatag ttgttaattt atctgaataa tttattgcat gaaatggcat cttaactttg
    16501 aagcgttcga taaagtgcgg atgttctata agaatctctg ttaaaagctc ccgtacaaga
    16561 gaggaactag cggaggaaac aagggacgag agttcggaaa gtgagtagtt ggattttttt
    16621 attggacgtt cttcgtaagc gaataagaca gcagccatgt gtttgcattt ttttccttct
    16681 atggcatata gacaatcaca agtcatgttg gtcttttcat cccaagtgat cactacctta
    16741 taatcttccg tgccagaaac tgttgcggac aagtacttgc ttgtatagtt caaatgacgg
    16801 acaaaaccgt gcagatgata gctgtaaccg cgttccaaaa cgttttcagg aaaatactca
    16861 agccaattat tcatctagtt ctcctttcat gaaacactta tttatattta gtataaagaa
    16921 acgtttaaga aaaaagtagc tgattttaca tatttgataa tcacttttgc tcgaattgtc
    16981 aaaaattcat tctccttttc ttttcttaga gaatgtgaga aaaagtaaaa gaatagcgtg
    17041 ttttaaagat ggaacttttt ttgtttttta tttatctgac aaaaatgaag tgattttgtt
    17101 agaaataaat aattgttcca attgataaaa gaggtatgat gtatcgcaaa ga
//
LOCUS       DACGEU010000058        17096 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.058, whole genome shotgun sequence.
ACCESSION   DACGEU010000058 DACGEU010000000
VERSION     DACGEU010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17096)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17096)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17096
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.058"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            287..694
                     /locus_tag="IXR40_001853"
     CDS             287..694
                     /locus_tag="IXR40_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361691.1"
                     /translation="MSYRVQLIISEDVESQQFGTNVINKVINPALSINAPLIPTALSF
                     SVTAVVSEIEDTEKIKIVEIEVLNKNEKQIFSTGEVSVSLPPQVNDINFNINARNVLV
                     EEAGEHYAVVKFNGTEIGRQIFDIKVNKPVEKN"
     gene            708..1109
                     /locus_tag="IXR40_001854"
     CDS             708..1109
                     /locus_tag="IXR40_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361692.1"
                     /translation="MLDIVPSNTHRSGSLINFAAIFACASVILASPVVVDASSTPKTK
                     NDNQLVITTKNEINTISSNDGKIFDVINTVLKRKAEINIKYDEDLNLYFFVIKTTSEL
                     FSSDYDVLDTLDNVLSDYKYMGKSVVATLGE"
     gene            1111..1482
                     /locus_tag="IXR40_001855"
     CDS             1111..1482
                     /locus_tag="IXR40_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361693.1"
                     /translation="MFDFNEYLSISKQIESDDKYNSKESYRRTAVSRAYYSAFKKSDE
                     YLKENYDIIYNGSSGKGSHQTVWNLFSTVKELNTLGIHNSGYRMLEKRKCADYIPNET
                     ITKTDMALMNREAEKIINKLT"
     gene            complement(1518..1817)
                     /locus_tag="IXR40_001856"
     CDS             complement(1518..1817)
                     /locus_tag="IXR40_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361694.1"
                     /translation="MLFNETQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINLY
                     YSNKNYFKIPAAKTRMKKDVYFLFDIVTDVPDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(1823..2053)
                     /locus_tag="IXR40_001857"
     CDS             complement(1823..2053)
                     /locus_tag="IXR40_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361695.1"
                     /translation="MMEEFIRKNISDEYADFYDQSSKKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETKFKNRSE"
     gene            complement(2489..3055)
                     /locus_tag="IXR40_001858"
     CDS             complement(2489..3055)
                     /locus_tag="IXR40_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HAQ4361696.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(3055..4011)
                     /locus_tag="IXR40_001859"
     CDS             complement(3055..4011)
                     /locus_tag="IXR40_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HAQ4361697.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(4011..4667)
                     /locus_tag="IXR40_001860"
     CDS             complement(4011..4667)
                     /locus_tag="IXR40_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HAQ4361698.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            5037..7055
                     /locus_tag="IXR40_001861"
     CDS             5037..7055
                     /locus_tag="IXR40_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAQ4361699.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     gene            7482..9896
                     /locus_tag="IXR40_001862"
     CDS             7482..9896
                     /locus_tag="IXR40_001862"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016183651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HAQ4361700.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            10244..11797
                     /locus_tag="IXR40_001863"
     CDS             10244..11797
                     /locus_tag="IXR40_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HAQ4361701.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(12178..13962)
                     /locus_tag="IXR40_001864"
     CDS             complement(12178..13962)
                     /locus_tag="IXR40_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4361702.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNCAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(13977..15698)
                     /locus_tag="IXR40_001865"
     CDS             complement(13977..15698)
                     /locus_tag="IXR40_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4361703.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLEIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            15798..16559
                     /locus_tag="IXR40_001866"
     CDS             15798..16559
                     /locus_tag="IXR40_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAQ4361704.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
BASE COUNT         5651 a         3037 c         3303 g         5105 t
ORIGIN      
        1 tgaggggaag tacatatagt tgttgatata gttgctaata ttgttagcta atttgttagt
       61 aaaactgtat acgaatttag atagtaaaaa aacagtttgt tccttatata gaggcacttt
      121 tactactgat taaatgtcag atatgcttac aaatatactt ataaatatgc ttacaaaatt
      181 agctaatatt tccgttgaca aagctttgtt actattgtta aactaaattg actagcaaaa
      241 gtgaaacata aatttattaa ataaatgtaa aaattaggag aaatcaatgt cttatagagt
      301 acaattaata atttcagaag atgtagaaag tcagcaattt ggcactaatg ttattaataa
      361 agtaattaat ccagctcttt ctattaatgc gcctttaatt cctactgctt tatcattttc
      421 tgtaacagct gtggtgtctg agatagagga tacagaaaag ataaaaatag tagaaattga
      481 agttttaaac aagaatgaaa aacaaatttt ttctacgggt gaagtatcgg taagcttgcc
      541 tcctcaagtt aacgatataa actttaatat aaacgccaga aatgtcttgg ttgaagaagc
      601 aggagagcat tatgctgttg ttaaatttaa tggaactgag attggaaggc aaatctttga
      661 tatcaaggtc aacaaaccag tggaaaaaaa ttaaggagac gatacggatg cttgatatag
      721 taccatcaaa tacacatcgg agtggtagct taataaattt tgctgcgatt tttgcttgcg
      781 catcggtaat tctagcatct ccagttgttg tggatgcaag ttctactccg aaaactaaaa
      841 atgataatca acttgtaatt actacaaaaa atgagattaa cacaatttca agtaatgatg
      901 gcaaaatttt tgatgtgata aatacggttt taaaaagaaa agctgaaatc aatataaaat
      961 atgatgaaga tttaaacttg tatttctttg ttatcaaaac aacatctgaa ttgttttcct
     1021 cagattacga tgttttggat actctcgata atgtattatc tgactataaa tatatgggga
     1081 aatctgtagt agcaactttg ggggaataaa atgtttgact ttaatgaata tttatctatt
     1141 tccaaacaaa ttgaatcaga tgataaatat aattctaaag aatcttatag aagaactgct
     1201 gtttcaagag catactacag tgcttttaaa aaatctgatg agtatttgaa agaaaattat
     1261 gatattattt ataatggaag tagcggaaaa ggaagccacc aaaccgtttg gaatttgttt
     1321 tcaacagtta aggaattgaa taccttagga atacataata gtgggtatag aatgttagag
     1381 aaaagaaaat gtgctgacta tattcctaat gaaaccatta cgaaaacaga tatggcgctg
     1441 atgaatcgag aagcagaaaa aataataaac aaactcacct aatgaatttc aagcgagttt
     1501 gtttgttatt tttttattta atctttgtat ctttctggat caacgaaagt atactttata
     1561 tagtcataac gccgatgatc gctacgtgcg tccggcacat cagtcacgat atcaaacaaa
     1621 aaatatacgt ctttcttcat tctagttttc gcagcaggga ttttaaagta gttcttatta
     1681 gaatagtaga gattaattaa taagctatct tcgattgcta aaaagaaaac ttctgaatcc
     1741 cacaccttat aaaaatcttt gacaaatcta ttcgaaggat caaatttaaa ccataattgc
     1801 gtctcattaa aaagcataac cattactccg atctattttt aaacttagtc tctacctcta
     1861 atatatatcg agtttttatt ttgccttcag agaatactgt ttcttttttt gcagttacag
     1921 gttgtttatt ttcggaaaaa gctaatatag ctaaaattga aacatccatc tggaatttat
     1981 cttttttact gctttgatca taaaagtctg catattcatc actgatattt tttctaataa
     2041 attcttccat cataaaaatc acctcaaaac gattatacga acttacgttc ttgttgtaaa
     2101 gcgatatttg aggggcaaaa aaggggcata atttgactga tattaagtta gctattgata
     2161 tatgaatgac atacaaaaat ataaaatctt ttaaaaatgc ttatatatca atgtttttgc
     2221 cattctttta tatatctgtt atatgtcaaa aaaatgtgtt caatttcaat ttgtatttga
     2281 ataaagaggt tgtgaaaaag ctgtcctgca tcaagtaata agaacagcca atcaaaaaca
     2341 gcttctcatg tttttgattt ggttggactt attaccgcag atataagctt ttgagcaccg
     2401 tgaataaaga ggttatgaaa tcaacgctct aacctgagta ttagagaaaa aaacgcaaaa
     2461 catatcattt atgttttgcg ttttttattt atcttttttt ctcaatacaa tataaaatag
     2521 gcggctggtt cttttggttg ataaaccgat aattcagcac attatatgtt tcctgtggca
     2581 gtttggaaca aaaagaatca accatatcca gttctttttc tccaccttca tgaccatagt
     2641 agacgacaag gatcaatcgt ccgcgaggca caagtcgttt caatatttct tccatagctg
     2701 tgcgtgtagt ctctggcata gtgatgattg ctttatcact ttttgggaga taccctagat
     2761 tgaaaatccc tgctttgaga ttttgttgtt cagctatcac ttctcctaac gtttcgtggc
     2821 cttgtagaaa caatgagaca cgttcttcta actgacgctg ttctagcctt tcacgagtag
     2881 catcgattgc ttgttgctgg atatcaaaac tatagacatg accagttttt ccgatgtgtt
     2941 ctgctagaaa aaccgtatcg tggccattgc ccatcgttgc atctacgacg tgatcccctg
     3001 gttgcaagat ttcttgcagt aatgtatggc tgaaatgcaa agcagtttgc aacatcagac
     3061 gctcaccttt ttccgtacat catattttcc ttggaagcta tctctgcgaa gaagttcttc
     3121 atcaattgca ttcaagactt cccatttttt caagctccac attggtccaa tcaaggaatc
     3181 ccacggcgca tcccctgtca aacgatggat gatgatctct tttggtatca tttccagctg
     3241 gtcgcaaatg acattgacat agtcaggacg gctcattaat tgaaggcgac cttcatgata
     3301 gtcccgcaac attctcgttt tgcgcatcag atgcatcaaa tggagcttga ttccttggat
     3361 atctgaatct aaaatggtgc gtctgacatt ttctttcatc atttctaaac tttcgcctgg
     3421 taatccgttg atcaaatgcg tacaaacacg gatattatgt ttgcgtaatt tagccacgcc
     3481 atctaaataa gtttgataat catgtgctcg gttgatcagt tttgaagttt cttcaaaagt
     3541 tgtttgcaat ccaagttcta cccataaata catccgctcg ttcagttcag caaggtaatc
     3601 aactacttca tctggcagac aatccggtcg tgtaccgact gataatccta cgacacctgg
     3661 taaattgact acttgctcaa atcgttcttt gattatttca actggcgcat gggtgtttgt
     3721 aaaattttgg aaataaacga tgtattgttg gacatgaggc catttttgat gcatcatgtc
     3781 gatttctttc tggaattgga ttggaagagg gtcttcaggt gcaacgatca tgtctcccga
     3841 accagataca ctgcaaaaag tacaaccgcc atgggcaaca gtcccatctc gattcggaca
     3901 gtcaaatcct ccatcgatcg gcaccttgaa aattttcccg ccaaactcat ttcgtaaagc
     3961 gtaattccaa gaatgatatc ttttatttcc ttctgaataa ggaaaagtca ttaaaagtcc
     4021 ttctttctgt aagagttatc tatttgtttt cttttttctc tatacactgg ataagtcagg
     4081 cacagccaag aaagactgag taagtagccg ccgatgatat cagtaggaaa atgaacgccc
     4141 agataaatgc ggcttatccc gacacttact ataataaaca tcatcagcaa ttgaagcaat
     4201 gtgcgtaagg ttcttttttg aacaaaagct ggaagcagaa atagtaaaga accgtaaaga
     4261 atcatactgc ctgctgcatg tccactaggg aaactgtaac ttgtttcaac tactaagtgc
     4321 gccaatgaag gacgctctcg catgaaaaat agtttgatca ccgggttgat gattccagca
     4381 attacaataa atccagaaac gaaccaaaat gtttctgccc tttttttctt ataccacatc
     4441 cataaagccg cacaagcaaa taaaatgatg acggtaagag gattaccgaa tttagtcata
     4501 aagagttggt agctgttcag atcaggataa gaagctctga caatgcctgt aaaccactga
     4561 tcgaaaccag aaagccacga cagatggaac tttacgatcc agcccaaaat gaaaaacagg
     4621 acaagaaaga agctaccagc cacctgaaat gatgttttat atttcataca attcctcctt
     4681 tgaagcaatg acttattata gcatttttgg tccagcgaaa aaaacggtaa agagataaaa
     4741 ccaatgtatg attcctcttt gaataaccaa tattcttata aaaaaaataa ctgtaatcgg
     4801 aaagacattt tttggtaatg caaatgaaat gttagggaaa taaaatcagt gtttttcgaa
     4861 atccttttaa acaagaacgt agacgtagga agaacttgaa aatgaacaga agttgttcat
     4921 tacggtaaat tacaatatga ttacaaaaaa caacaaagct cttaaataac ttttaataaa
     4981 tattaagaga agttataatt attaataata gataaattga agttggagga tagaagatgg
     5041 aaaacattgc aagaaaagaa cggagacgtt tagaacagac caaacgtttt cgaaaagcaa
     5101 aacgaggggc agcaatcgtg ggaactgcga tggtaggctg ttctgtcgct gccccattag
     5161 tacagccggt tcctgttcaa gcggatgaaa cacctgttca gttcggcgca agaatcaata
     5221 cagcggcatt tatcacagaa attgctactt atgctcaacc aatcgctcaa gccaacgatc
     5281 tatatgcatc agtgatgatc gcacaagcag ttgtagaaag cggttggggc agtagtgcgt
     5341 tatctcaagc accttattat aatctttttg ggataaaagg cagctatcaa ggacaaaccg
     5401 tctacatgga tacgcttgaa tttttaaata atcaatgggt aaataaaaag gagcctttcc
     5461 gacaatatcc ttcttttgct gaatctttca atgacaatgc ctatgtactt agaaatactt
     5521 catttggcaa cggttattac tatgccggta cttggaagag caacacgaaa tcctatacag
     5581 atgcgacagc ttgtttgaca gggcgttatg cgactgatcc tggttacgca ggcaaattaa
     5641 ataatatcat cgcaacttac ggattgaccc aatatgatac accagctagc ggaaacgcag
     5701 gcggtggagc gactacaggt ggcaataata ctggaagtgc aggtagtact ggcggttcaa
     5761 gcaattctgg taatacaaac tcaggttcag caacttcgac cacttatact gtccaatctg
     5821 gtgattctgt ttggggaatc tcaaataaat tcggtatcac aatggatcaa ttgatccaat
     5881 ggaacaacat ccaaaacaat ttcatttatc caggacaaaa actgacaatc aaaggtagcc
     5941 aggaaaatgg ctcttcgacg aataattccg gtaacaatac caactcttca ggaaatgctg
     6001 gtacatcaaa cggaggacaa acaactggtg cgaaatacac tgttcaatct ggtgattctg
     6061 tttggaagat ctcaaatgat cacggaatta cgatggctca attgattgaa tggaacaata
     6121 tcaagaacaa tttcgtttat ccaggacaac agctaatcgt atcaaatggc ggttcttcta
     6181 atgctggagc aaatactggc tcaaatactg ggaatacaag tggctctagt tcgtccagct
     6241 caagttcttc taatacagct tcaggaacga aatatacagt taaagccgga gactctgttt
     6301 ggagcgtctc aaataaatac ggaattacga tggctcagct aatccaatgg aacaatatcc
     6361 aaaataactt tatctaccca ggacaacaac tgactgtttc aaacagtgga tcaacaaaca
     6421 gcacgtcagg taatacaggt tcgtcaacca atacaaataa cagcagttca gttaatactg
     6481 gcagcagttc gtctcaaggc acttataccg tgaaagcagg tgaatctgtt tggagcgtgg
     6541 caaataaaaa cggcatcacg atggatcagt taatcgaatg gaataatatc aaaaacaact
     6601 tcatttatcc aggacagcaa ttgatcgtta aaggtggaac ttcggcaaat acaaatacag
     6661 gttcaactac ttctgcagcg aaaccaaata caccgaatac gtctgctacg acaagtacat
     6721 catccactgg taatacgatg tataccgtga aagcgggcga gtcagtttgg agcgtagcga
     6781 acaaacatca tatcacgatg gatcagttaa tcgaatggaa taatatcaaa aataatttca
     6841 tctatccagg acagcaagtg attgtgaaga aaggttcatc tcaatcaaca aaccaacaat
     6901 cagttactgg ttcgaaaacc tatactgtga aatctggaga atctgtttgg agtgttgctg
     6961 acagtcatgg aattacaatg gctcaactaa tcgaatggaa caatattaag aacaacttta
     7021 tttatccagg tcaaacgttg attgtagcta aataaaatag ctgttcgaag aaataacgat
     7081 tgaattccac aaaaatattt gttactataa ggctacttaa atatgacaac acttgaaaag
     7141 gaagtagtaa aaagactgaa gtttcagaga gcgcatggct ggtgagaatg tgcacggatg
     7201 cttttgaact cgcctttgag ttgcccttgc tgaatacccg agtaagcaag cggcggtgac
     7261 ggccgttaca acgttcgagg ccttttcact aaggtaaaat taggtggtac cgcgtagatt
     7321 acgtcctata aaaagagcaa tctttttata ggattttttt atttcttttg tgaagtttga
     7381 gaaaacaaag caaaaggaaa taaaaataaa cagattctgc cggttttttc gttatattta
     7441 taatagaaac aagtgttttc aatagaacag gaggacagca aatgagttac aatcataaag
     7501 aaattgagaa aaaatggcaa aaatactggg caaaaacgaa tactttcaac acccatgatg
     7561 atcctgaaaa gccaaaattt tacgcactgg atatgtttcc ctatccatcc ggtcaagggc
     7621 tacatgtagg gcatcctgaa ggttatacgg caacggatat cctttcacgt gtgaaaagaa
     7681 gtcaaggata caacgtgctg catccaatgg ggtgggatgc attcggtctg cctgctgaac
     7741 aatatgcgct agatacagga aacgatccag ctgagtttac ccaaaaaaat atcgaaacat
     7801 tccgacgcca aatcaattct ttaggattta gttatgactg gaatcgcgaa gtgaatacaa
     7861 ctgatccgga gtattataaa tggacacaat ggatctttac gaagctttat gaaaaaggtc
     7921 tagcttatga agcagaagta gcggtaaact gggtacctga attaggaaca gttatttcaa
     7981 atgaagaagt gatcgatggg aaaagtgaac gtggtggcta tgatgtagtc agaaaaccaa
     8041 tgcgccaatg gatgctgaaa atcactgctt atgctgatcg cttattggat gatctagaat
     8101 tagttgattg gccagaaagc attaaagaaa tgcaaagaaa ttggatcggt cgttcagtag
     8161 gagcaaatat tgaatttaaa gtggctggta cggataaatc ctataccgta tttacgacac
     8221 gaccagatac tctattcggt gcaacttact cggttcttgc acctgaacta gatcttgtta
     8281 gagaaattac gacccctgaa caaaaagctg ctgtagaagc ttatatcgaa gagacagcta
     8341 aaaaatcaga tctaaagaga acggatcttg caaaagaaaa aacaggagta tttactggtg
     8401 cttatgcaat caatccagtt aatggcaagg aaatcccaat ctggatcgcc gattatgtat
     8461 tatcttcata cggcacagga gccatcatgg ctgttccagc acatgatgaa cgtgactttg
     8521 aattcgctca aactttcgga ctagaaattc ttccagttat cgaaggtgga gatgttgaaa
     8581 aagctgctta cacagaagat ggtacgcaca tcaactctga atttctagac ggcatgaaca
     8641 aacaagaagc aatcgataaa atgaatgaat ggctagaaga aaatggcgta gggaaaaaag
     8701 aagtcagcta tcgcttacgt gactggctat tctcccgtca acgttactgg ggtgaaccaa
     8761 tcccaatcat ccattgggag gacggaacag tcacagctgt cccagaagaa gagctaccat
     8821 tacggttgcc taagacaaaa aacatcaagc caagcggtac tggagaatct ccattagcaa
     8881 atatcgagga gtgggtcaat gtcgttgatc ctgtaacagg taaaaaaggc cgtcgcgaaa
     8941 cgaatacaat gccacaatgg gcaggaagct catggtatta cctgcgttat atcgaccctc
     9001 ataacaaaaa agaactagca gattatgaaa agttgaagcg ttggctacca gttgacatct
     9061 acattggtgg agcagaacat gcggtacttc atttactata tgcacgattc tggcataaat
     9121 tcttatacga tatcggtgtt gttcctacaa aagaaccatt ccaaaaacta tacaatcaag
     9181 gaatgatctt aggcgaaaac aacgaaaaaa tgtcaaaatc tcgtggtaat gtagtcaatc
     9241 ctgatgatgt ggtcgaaact tacggtgcag atacactgcg catgtacgaa atgttcatgg
     9301 ggccattaga tgcttcgatt gcttggagcg aaaatggctt agaaggaagc cgtaaattct
     9361 tggatcgtgt atggcgtttg atcgttgatg agaacaataa aatgcgtgac cgtatcacta
     9421 cattgaatga tggcaagctt gataaagtgt atcatcaaac agtgaaaaaa gtgacagaag
     9481 actatgaaaa tcttcatttc aatacagcaa tctcccaatt gatggtcttt atcaatgaag
     9541 cctataaagt ggacgctctg ccttatgaat atatcgaagg atttgttcaa ctactcgcac
     9601 cgattgctcc tcacatgggt gaagaactat gggcaatcct tggaaatgat ggtggtattt
     9661 cttacgcacc atggccaaca tacgatgaag cagcacttgt tgaagacgaa gtagaagttg
     9721 ttttccaagt aaacggtaaa gttcgtgcga aaagcaatgt tccccgagac ttaggaaaag
     9781 atgagctaga aaaagcagca ttagccaatg aaatagtgca agaatatatt gaaggcaaaa
     9841 cagtcagaaa agttattgcg gtaccaaaca agttagtcaa tatcgttgct aattaattgg
     9901 ctctttgtca ataaggactg atgagttgtg caaaatcaaa tctgggccag aatgaacttc
     9961 attctgtctc agattttttg ttatttcaaa ttgattaatt gattgatcaa aaaggttttg
    10021 attttcatgt tctcaaacac gttcaatgtc tttttcttct gaatggtctt gtaagagatc
    10081 tctgtaatca tcaaattttt gtctattaat cttagtattt tttgatgtat aaactacctg
    10141 aaattgagag tacataccaa attcataaat tttttattag tgggactagt gattgtatgg
    10201 attttgacgc ataatgaatg aagtatgaga aaaggagaga caaatggatc aagaactatt
    10261 tattatcgaa gtattatcag ctaaacaaaa aattatcgag aaagcgaaaa aaagagcgaa
    10321 aagaataatg ttcaagcttt taagcttagt atttttctct ggtttgcttt ttttcggagc
    10381 tgtatcgttc ctatatcgcc atatgagtgc agtagtccgt tcagctgaag ggatgcaaaa
    10441 attaaataat ttgtatcact tttcgtgggg agttggcgga ataacaattg ttgtgcttat
    10501 tgtttttctt ctacttattt ggctccgtta ccatcaattg tcgcgtcatt tcgatcaatg
    10561 gcttagtcaa agagcacaac agtttttaca taataaacca acttctcaag atgatgacta
    10621 tctttatttt gagaagactt cgacgagtca agcttttcgg atacaaaaaa gtgattgcca
    10681 gttattgctg agatcacttg atgatttacc tatctactta ggcgaaagca aatcaaaatt
    10741 cggaatgaac acattccata tttttttact agaaaacgaa cccagatggg aaaaaagcca
    10801 gtcttcgcct ggtggatacc tgacaactaa gatgagtaca ttagtcactg gttttttcct
    10861 cattctttta gctggaacaa tctattatgg gagatacact cagccaaaaa tgtcttctca
    10921 tataaatgct gcttctcaca tgacaatgaa ctcaactaac gatacgcata tacaaaagac
    10981 aaatgaaggg ttgttagctg atcctaagca aaaggtaaat ttgacaacac aaaagataaa
    11041 tgatctcaaa cttgatacag agacgcactc tctctatatg acaacagata gtggtgctaa
    11101 ttgggtattt gtgccgattg attcgcaatg gttgcgtttt ggcgaataca ccctgacaac
    11161 ggggctgatt cctgaaggtt attggatgga caacacatat gatatttccg ccgatttctc
    11221 atggtttatc tattcttctg gggatgatgt acgtctgctg acttcaagag ataatggtaa
    11281 aacatggcaa acgtctatta tcacccaatc agttcagccg atacgttatc gaaaagcggt
    11341 attttatggc aacgatggtc tatttatctg tacatcagcc agtgggatgt ctgcagaaac
    11401 tttgtacatt tacactacta tggatggcgg aatcacttgg ataaaaagtg gaagtacaat
    11461 gatcaatcag ccagtacaaa atgtcagctt cgttacaact tctttaggtt ttgtttcgac
    11521 acgtgaaagt ttgttttata caaacaacgg aggacgctca ttcaaagaat cagttctgtc
    11581 gattccggaa aactatcaga caggggggat agatcttttt caatcaccaa atgaagttac
    11641 tcaaataagc gcgaatacgt tagagacaaa attttatttg ttgaaaaaag gaccaatcga
    11701 tgcagggaaa atgtttgcct gcctcttccg ttcaactgat aacggggaaa catggcaatt
    11761 cgttcagcaa ctatcgcaag tagaacaagg agattaaaga agagagattg tgagcctgac
    11821 gttcagcacc gagtcacaag aaacaaattc aaaaaacagc ttctcatatt tgttgaatag
    11881 tgtaactcgt gattcggagt tgacaagagc aacaagaagc gattttgaag tatagcttct
    11941 cgtattttac aagatcgtgt cttattgccg ataggttgtc tcttgaacac cgtttattcg
    12001 taaaaaggga ttgtgacaag tcttttgtca ctacttaccg aacgaaactg aaggagctat
    12061 ccaaaaagta tcattagtat tattctttgt gtttctagtg gcaccactag tacatttaaa
    12121 aaagctatcg atcatggact aatcatacat gatcgatagc tttttagata atgtttgtta
    12181 cgctatctga aattgactat tataaagact ggcataaagc gttggtgatt ggagtagttc
    12241 agaatgtgtt cctttttcga cgatatcgcc attcttcatt acaaggatca tgtctgcatt
    12301 ttcaatcgtt gacaaacggt gtgcaatcac aaaacttgtc ctatcttttg tcacagcttc
    12361 cattgcttgc tgaatcaatg cttctgttcg tgtatctacg ctagaagttg cttcatctaa
    12421 aataacgaca ggaggattcg ctagaatgac tcgagcaatt gtcaataatt gttgctgtcc
    12481 ttgagataac gtgccgtttt cgctagaaat gatcgtatca tatccgtctg gcagtgttcg
    12541 aataaagtga tcacattgtg cgatttcagc cgcttcgata atttgttctc ttgtggcatc
    12601 cattttcccg taggcgatat tatcagctac cgttccttca aacagccagg tattttgtaa
    12661 aaccatccca aaagaacgac gtagttctcc acgtgaaagc ttggtaatat caagaccgtc
    12721 gaattcgatc tttcctttat tcagttcata aaaacgcatc agcagattga ctaaagtcgt
    12781 ttttcctgca ccagttggac caacgatcgc taccgtttgt tttggcttta ctgaaaaatc
    12841 gacttgattc atcaatattt tatctgatgt gtaaccaaac tgtacatttt tgaaagctat
    12901 ttttcctttc ggttgttcta aaagtcttgc atctggaagg tctggaattt catctgtttc
    12961 atctaatatc tcaaatatcc tatcgattgc tgccattgcg gattggatcg agttgatcac
    13021 ataagaagcg gtagaaattg gttcagaaat ctgattgatg tactgaagat aagcttgtaa
    13081 gaagccgatc gtcacaccac ctgatagaac aagcatagca ccgaataccg cacttatgat
    13141 gaaggcgagt tgattaatga aacgaatggc cggatagata gcacagttca taaattgagc
    13201 acgtttaaaa gcgttgtatt gctttttatt tacttcgtgt atagcagctt ctgcatgagc
    13261 ttgctgattg aatgttttga ccactagatt accagctaag atttcttcca ttcgattatt
    13321 taaaacaccc agttcatact gattctgttc agaaatctgt ttgtttttgt tcgcaatctt
    13381 agttgtaaca attgaactgc caacgatcag caataagacg agcaaagtaa gcttgctttc
    13441 gatataaaac agcatcagac cagcagcagc tattgttacg acagaagtaa aaaattgatt
    13501 gatacctgtc aataacactt gagaaagttg attgagaccg gtagttgtcc gactaatgat
    13561 gtcacctact tgatgattgt caaaaaacga catcggtaat gttttgaatt tttttgtgat
    13621 ttcttttcgc accctcaatg tgatcttttc gcttaacgct gccattgtcc gttcctgaat
    13681 aaatgaagtg atgctgctta agactgaaca gccgatcagc aataagacag ggaacaacaa
    13741 tgcttgtttg atatcactga aagaaagctg tccaatacct gtttttctta tttctgataa
    13801 gagatcatcg atcccgattc ccatgatcaa gggcatggct acgactaata ggttcccgaa
    13861 taaactgcat agaaacaatc cgtaaaaata tttatgttca ggtttgatca ttttccaaaa
    13921 acgtatcaaa gcacgcgtgt tcaacgtttt tttcttttcc atcgtatccc ttctttctat
    13981 attccttgtg attttgcaaa ctcctgataa gtttggcaat tagacagtag ttcttcatga
    14041 gtaccttgtc caacgatttt tccttcatct aaaacaatga tgttatctgc ttgttggatt
    14101 gtactgaggc gttgagcaac aatcacgaga gttttctccg acatgtgttt atgaagggct
    14161 gctcttaatg ctgcatctgt tttatagtct aaagcggaga aactatcatc gaatacatag
    14221 atctctgctg gtttgatcaa cgctcgagca atacatatcc gctgtttctg gccccctgaa
    14281 taattagaac cgccttgagc aacaaagctg tccaatccgt caggaagggt gtccactagt
    14341 tcttctaatt gagcgatctt gatcgcttta gacaactctt ctgttgaggc atattcattt
    14401 cccatctgca agttgcttaa aattgtcccg ctgaataaga aagccttctg agggacataa
    14461 ctgatgtggg agcggatctg ttcttgagtc atttgagtaa gaggaatacc accaagggtt
    14521 acttttccta tcgtagggtc actaagtctc aagagaagtt tcgccaaact actttttcca
    14581 gatccggtcc cgccaacgat cgctgttgtt tttcctttag gtattgtgaa atcaatatct
    14641 tctagaactg gatcagagat ttcagtatat ttaaatgtga catgttcaaa agcagctgca
    14701 tttgtctgat caaaggttgg ttcagctact gttttgatcg tctcttcctc aatttcgatc
    14761 tctgcttgca gtatttcttc tatccgtcgt aatgaggcaa acgatttagg gataatgacc
    14821 aataccatag ctgcgatcat caagtaagca agtgtcagca tagagtattc gactacagca
    14881 gtcacgacac cgatttgtaa tgctccttct gctacaagat ttccgccaaa ccacaaaata
    14941 gaagcataaa cgattcccat gagcaaaaaa gcaattggag tgacccaagc aaatattcgg
    15001 ttcactttga tcatttgatt agcatagtca gcaaagctct tattcgttcg cttttcttca
    15061 tatgattgat tatcaaaggc acggatcata ttaatcccag taaagaattc tctcaatgtg
    15121 atggtgatcc gatccatttt tggctggata ctcaaagata aaggtgcccc tcgtttcatc
    15181 agtcgataaa caatccatac ataaaaaaca acagagatca atgtaaccca tgttagtaat
    15241 agagaataac gaaacatcat gagaatggtg aaaacgcaaa taaccggtgc tggtaagatc
    15301 atttggcaaa ataaaacaat catttgctgg acattatcga catcattcgt cattcttgtc
    15361 aaaagagatc cagaactaaa acgactgata tccttcattg acagctgttg gaatttacgg
    15421 aaatatttct cccgcgtttg gaatccaaac ctagcggaag ccaatgctga aaagtaacta
    15481 gaggcaactg cagcgattgt tcctagaaac gctacaagca gcatttcaac tccaattttt
    15541 tttataactg aggcttcgcc acttgctata cctgtgtcga tcagctttgc tactaatttt
    15601 ggtacaccta atgtaccggc gatttctaaa cagatcatca caaaggtaag gagagcgagt
    15661 cctttgtttt tctgtaagaa tgtttttaag atagacatat tattcctcct tttttcctga
    15721 tacttttcga ttctatacct tcaagtaact tgaaggtcaa tagaaaaaag aataaactga
    15781 aaaagaggtg agaaaaaatg aaaaaaatgt atacgattgg ccaagtatcg gaactatttg
    15841 atttgccaaa atcaacgatc cgctattggg atgaacaagg attaatccgt tcaagtagac
    15901 aagaagagaa tgattatcga ttgtttgata tcgatgatat ttttatgctt tatgatatcg
    15961 ttttttatag aaaattagat ataccgatca aacagatgaa gaatttatat ggaaaaacat
    16021 tgacggagtt atatgagaca cttgatgaaa cagaaagaag aatccataaa gaactggtgg
    16081 tgatgaaaca aaaacaaaaa gagataaggg agcaaaaaaa acagttgaaa ttgatgatcg
    16141 atacaaacga ggaagaattt cctgtagaag agatcccttt tgactgtatg atctcaacgg
    16201 agtttgaaga tattgtggaa atcaaaaaat ttctacctaa ctattcaagc tttgggatga
    16261 tgagtatgcc agcttccagt tcacagacga tgtatggatt ttttatcgac cctagtgaag
    16321 tacatttatt tactcaagac gtgatttggg agaaaaaaga tacggctgtt tatcgtcgat
    16381 tcttattgaa atccgagatg aaccatgcgg aacgtaataa tattttagaa atcagagaaa
    16441 gaatgtatga aaaaggatgg aaaacaggag aagtgatcgg ccagtatcta ttgacgaata
    16501 cggatgaaaa caatatcaga actgaatatt atcatgcatg gatagaaatg aaaaaatagg
    16561 aaatatgtgt ttaagataac tcgaaaatga tggttgtttt agttataaag aaaaattttc
    16621 tggttcgatt acgggtttaa tgtgggggat tattagtcgt ggatagatag aattttagtt
    16681 ttttagagga aatatgtctt taaaaatgga atggttgcaa ttcttagcga tatatacgat
    16741 gtaattgtcc tcttaaaaaa gtatggaaaa ataattgtat tgggtgttat gtataattca
    16801 tggtgaactg agactaatga gaagaaaaat tcatattgtt atgagtgaga ttgtatcaga
    16861 tgagaatgat aaattaaata ggtgcataaa agcattacac ttaaaataca ttgttgctta
    16921 cattattaca atatgttaat aaggcaaaaa taaatagatg gattgaataa acatattttt
    16981 taatcaaata gtccctactg tgactttcct cagctatcgg tgatactacc gatagcattt
    17041 ttttgcttat aaaataatta taagtattta gagatttttc ttctaacatt cttcaa
//
LOCUS       DACGEU010000059        17008 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.059, whole genome shotgun sequence.
ACCESSION   DACGEU010000059 DACGEU010000000
VERSION     DACGEU010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17008)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17008)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17008
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.059"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..127)
                     /locus_tag="IXR40_001867"
     CDS             complement(<1..127)
                     /locus_tag="IXR40_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EntF family bacteriocin induction factor"
                     /protein_id="HAQ4361705.1"
                     /translation="MEEKNRLNAKQCSDQELKKIKGGAGTKPQGKPASNLVECVFS"
     gene            complement(231..542)
                     /locus_tag="IXR40_001868"
     CDS             complement(231..542)
                     /locus_tag="IXR40_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HAQ4361706.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPSPLINRLVNYLYFTAYTNKIRFTEYQEELIRNLSEIGRTAGINGLYRADYGDKSQ
                     F"
     gene            complement(544..741)
                     /locus_tag="IXR40_001869"
     CDS             complement(544..741)
                     /locus_tag="IXR40_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterocin"
                     /protein_id="HAQ4361707.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            complement(1135..2862)
                     /locus_tag="IXR40_001870"
     CDS             complement(1135..2862)
                     /locus_tag="IXR40_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAQ4361708.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(2855..4048)
                     /locus_tag="IXR40_001871"
     CDS             complement(2855..4048)
                     /locus_tag="IXR40_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HAQ4361709.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(4235..4879)
                     /locus_tag="IXR40_001872"
     CDS             complement(4235..4879)
                     /locus_tag="IXR40_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAQ4361710.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(4973..5107)
                     /locus_tag="IXR40_001873"
     CDS             complement(4973..5107)
                     /locus_tag="IXR40_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HAQ4361711.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(5109..7241)
                     /gene="feoB"
                     /locus_tag="IXR40_001874"
     CDS             complement(5109..7241)
                     /gene="feoB"
                     /locus_tag="IXR40_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HAQ4361712.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(7238..7711)
                     /locus_tag="IXR40_001875"
     CDS             complement(7238..7711)
                     /locus_tag="IXR40_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HAQ4361713.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            8112..8336
                     /gene="nrdH"
                     /locus_tag="IXR40_001876"
     CDS             8112..8336
                     /gene="nrdH"
                     /locus_tag="IXR40_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HAQ4361714.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            8495..10654
                     /gene="nrdE"
                     /locus_tag="IXR40_001877"
     CDS             8495..10654
                     /gene="nrdE"
                     /locus_tag="IXR40_001877"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HAQ4361715.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFPSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYATAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            10704..11669
                     /gene="nrdF"
                     /locus_tag="IXR40_001878"
     CDS             10704..11669
                     /gene="nrdF"
                     /locus_tag="IXR40_001878"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HAQ4361716.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(11758..12897)
                     /locus_tag="IXR40_001879"
     CDS             complement(11758..12897)
                     /locus_tag="IXR40_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAQ4361717.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAI
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(13206..13919)
                     /locus_tag="IXR40_001880"
     CDS             complement(13206..13919)
                     /locus_tag="IXR40_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HAQ4361718.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(14173..14874)
                     /gene="nagB"
                     /locus_tag="IXR40_001881"
     CDS             complement(14173..14874)
                     /gene="nagB"
                     /locus_tag="IXR40_001881"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HAQ4361719.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            15108..16640
                     /locus_tag="IXR40_001882"
     CDS             15108..16640
                     /locus_tag="IXR40_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAQ4361720.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(16831..>17008)
                     /locus_tag="IXR40_001883"
     CDS             complement(16831..>17008)
                     /locus_tag="IXR40_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAQ4361721.1"
                     /translation="VFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQ
                     TVVFKGKRNLENKK"
BASE COUNT         5279 a         3495 c         2910 g         5324 t
ORIGIN      
        1 atgaaaaaac acattccact aaatttgatg ccggttttcc ttgaggtttt gttccagcac
       61 ctcctttaat ttttttaagc tcttgatctg aacattgttt agcatttagt ctattttttt
      121 cttccattac gattccccct acaaactata aatactttta tgtcactgat tcaatatacc
      181 tatttttcta atcaaaaaat tttgagacat atttaatatt ataagtatca ttaaaattga
      241 gatttatctc cataatctgc tcgatataaa ccatttattc cagcagttct tccaatttca
      301 ctcaaatttc ttattaattc ctcttgatat tcagtgaatc ttattttatt agtataagca
      361 gtaaaatata gataattcac caatctattt attaaaggac tgggatctaa ttcatatttt
      421 tgtttttcta attttaaata taccttttgt aaaacctcaa gaatatcaga atatttagga
      481 tctttactta tagatatatc attatataat tcatgaacaa tttgcttagc attttttttc
      541 attttagcac ttccctggaa ttgctccacc taaaaaacca cctatagaca ttcctgcaat
      601 acaagtagtt gccttggccc aatcgaccgt acatttattt ttagtgcaat acactccatt
      661 tccataatat tttccactat gagtggtacc cccatagata agttgtgtct ctttaataga
      721 caaaattttt aaatgtttca taatctaatc acccctaaat taatgttttt agactattat
      781 tctaacattc attaaatttc aaaaaacaat tccttcttga aacgtagcaa aataattcct
      841 gaataagaat ttaatcactt ttaagtatat aaactatgta tattctttaa tattttttga
      901 gaatgcactt cgtacataat aaactttaat cacattagtc tttcatacct acgatcgatc
      961 tctttgactc gcacccataa attcataata gtttgtcggc gtctttgaac gtttcgaaga
     1021 tgagctacgc attctctttt tttatagaca aaaaagatag agacgaacat ggagcttcca
     1081 aatttggata tttgatccaa ttttggaagc tccatttatt tcgtgtctgt ctttttattt
     1141 tttccagctt tcgactaatt cttggttctc tttgatccag tcttttgctg cttgctgtgg
     1201 atcttttcca ttgttgattt ccaacataac tttttccata tctttttctg accaatggaa
     1261 attgtctaat actttgtaag cttctggctg gtcttctttc aatccttttc gaaccatcgt
     1321 atggatctgc tcttcgcttc ccattccgtt ttcaggatct tctaagtatt tcagatcata
     1381 tttggcaaac atccaatgag gtgtccatcc tgtaactaca attggttcgt gttttttgat
     1441 cgcttgacct agtgcaacgg tcattgctcc tgaagaagat gtctctactt tccagtcttt
     1501 caagttgtca tatttttgga tcgtgttttc agcagccgta actacaccag ctcctggctc
     1561 gattcctatg attttcttac ctgcctgatc ggttaactca tcgatcgaat ttacatccat
     1621 gtaggctggc actgctaaac caacttttgc tcctgtcaaa ttggcaccta ggtcttcgac
     1681 ttgatcttta tattgtgcat attgtgaacc atgagtttta ggtagccaag ctgaaaccat
     1741 ggcatctgac tcgccatttg aaacagattt ccacatgatt gaattatcta atggcgtcat
     1801 cgttacatca tagcccattt gtttcaatac ttcaccgact acatttgttg aagcaacttc
     1861 tgtatcccat tcaacataag ataagttgat acgttttgtt tctttggcag atgaaaaact
     1921 ccctatacca atcgcaccta agatcactac tactacagca ccaatgatca gtccttgacg
     1981 ttttttactt ttctgtgttg ttgctcctgc agctttttta ttgtttggct ggttcaaatg
     2041 ctgtgtaaaa cggtcaatga tgattgctaa gataactaat gcaaccccgt tgacaaatcc
     2101 attcccgact tgtgctcttt gcaatgctga taatacgccg cgtcctaagc cgggtgcacc
     2161 gatcatagag gcaataacga ccattgaaag tgacagcatt gttgtttgat tgatccctgc
     2221 catgatcgta cttttagcta aaggcaattc tagtttgaat agtttttgac gacttgtgct
     2281 cccgaatgaa tcagaagctt ctactaattc tttaggaact tgtcgaatcc ctaaattcgt
     2341 aaaacgaacg gttggtggca gagcaaagat gactgaggca aatacccctg gaaccatccc
     2401 gataccgaaa aatgcaactg ctggaatcaa ataaacgaat cctggcattg tctgcataaa
     2461 gtcaaggatc ggtttgataa tactttgggc tttactgctt tttgccatca agatccctaa
     2521 tggtacccca atgatgatcg agatcacact agataaaaga acaagtgtga cagtattcat
     2581 caaatcattc catagacctt ggttataaat aaaccataga ccgattaatg tgaacaacgt
     2641 aagtcctgga cgtttcttag aaataaagaa agctgctacc gtcaataaca agataaacaa
     2701 aggagctgga atcactaaca gtaaatttgt aatccccgac atcactgcct gtccaatcgt
     2761 ttgtaaaaat gaaaataggc cagaaaaagt tgtcgtaaac cattctgtga tattttctac
     2821 ccagtttgcc actggtaatt gatagttcaa tagattattc atgttcactc acctcgcttg
     2881 tttctgctaa tgcttcaatc acactacctc ggatgacgac accttttaat tttccatcct
     2941 ctacaactgc aagtggagtc ggtgagtcat aaataatatt gaaaatatca cttaccacca
     3001 tgtctttccc aatcaccgtc acattttcat ctaggaagtc gatcaatgga cgtttttgct
     3061 tcctagcttc taacgcttga tctgcagtga tgatcccttt caggtgtctc tttctgtcaa
     3121 cagccatcag catgctgact tcttcattac gcatccttgt caatgcaacg tttggtccat
     3181 cagattcgat attcgtcgtc aatgcaggta ccatgatgtt ttgagccgta agcactttgg
     3241 aacgatcgac ttcttccaca aattcacgta cataatcatt tgctggattg gtcaatattt
     3301 cttcacctgt tccgatctgc atgatttcgc cgtctttcat caaggcgatt ctgtccccaa
     3361 tccgtaaagc ttcattcaaa tcatgggtaa tgaaaataat cgttttttga acattggctt
     3421 gcaggtccag taattcgtct tgcatttctc gccggatcag cggatcaaga gccgagaacg
     3481 cttcgtccat cagcaagatc tcaggatcat ttgctaaagc tctggctagg ccaacccgtt
     3541 gttgcatccc accagataac tgactaggat attggtcttt aaatgaaagc aaactagaat
     3601 tttctaatgc tttttctgct ttttcttgtc gttcttcttt aggtacacca cggacttcta
     3661 acccgtattc tgtattttcc aagatcgttc gatgtggaaa cagaccgaag ttttggaaaa
     3721 ccatattgat tttatgacga cggacttctc gcaattcttc tttgcttaac ttcgatacat
     3781 cttctccatc aatatagata ctgcccgaag ttggctcaat cagacgattc aatagacgga
     3841 tcaatgtgga tttcccactc ccggaaagcc ccatgatcac gaagatttct ccttctttta
     3901 cgtcaaaatt cacgtcatac acaccaaccg ttgcaccggt tttctttaaa atctccgttt
     3961 tcggctggtg atcattcatc atatctaaag cggcttgtgt ctttttacca aatatctttg
     4021 ttaaatgttt tacttctact tttaccaaac aaattctcct tttttatgta aattcatttt
     4081 tctttctgaa aaaagtgacc acactatgtt aacatcatgt agtcactttg tcaaaaatga
     4141 aagaaatttg cttgtccaaa ctgaaaaaaa cttggctaaa tctttgtaaa taaaaggttt
     4201 agccaagtta atattttttt aatatttcac acaatcattc tgcaagctga tgctccgggt
     4261 aaaaaaagtt tgtcatacgc tgtagtgtat attcatttcc aataaaatga acgatgtccc
     4321 ctgccgtaaa tttagcatag gggccaggtg aaacaagcag ttcttcatta tgagaaattg
     4381 cgataactgt ggcgccagtc gcctgccaga tattcaactc gctaattgaa cggtccagat
     4441 gcattgcttt ttctgataaa gataattcaa acggaagtaa aggattcatc ttatgtattc
     4501 gcttcgtttg attgaccagc tgatccaata attgagaaaa atgattcagc tcatcttgtt
     4561 gcttctccac acttgccatg atttctgctt ttgtatcttg gatggattgt acatcttgat
     4621 attgcaatag gaaatctttt gctttttcct tcgaagcaac aaatgcccca cttccatgcc
     4681 gtacttccat gattccaaga tctaccagca cattgatagc cttgcgggta gtctcaggag
     4741 aagcattgta cgtactggca agtgttgagc gggcatggat cttctcaccc actttatatc
     4801 ggttttcaac gatacgttcg gctaaatcaa cagcaatctg ctggtagcgc gggcggacga
     4861 tttttttctt tccagacatt ttctttcctc tttctttttt tactttccct catcttacta
     4921 tgctctagca aaataagcaa aaaaggggag aatagcctct tgcaacgact gatcatcgct
     4981 tgatctgttc cttttttact gggcaagctg tttgacagtc atcacaattc ttaccggatt
     5041 ttaaacgagt atagacaatt gcgcctgcac ttccaaagat taacacactt aataagaatg
     5101 tcgccatcct attcctctcc ttctaatgac aatatagtat aaaactggtt cttggatttt
     5161 ggctgacgga acaaaacata aacgagtcct atcatcagta aaatagcaag atacgtccct
     5221 aacgctacct gtccaccctc caataagtgt cccaactgat aaatcacaaa actaactaaa
     5281 taagctaaac cgcattgata gcctatggcg atccaagtcc atttcttggc attcatttcc
     5341 cgatggatag ccccaattgc cgcaaaacaa ggcgcacaaa gtaaattgaa ggctaacaat
     5401 gaataagctg ctgcgggagt atatgtgtgt tgtagcactt gccagatttc tctgccattt
     5461 tcggatactt ccgcatgacc aaacaaaata ccaaatgtgc caataatatt ttctttagcg
     5521 accaatcctg taatcgctgc gactgttcct tgccagtttc cccaaccaag cggctgaaaa
     5581 acaactgcca ggattcgccc gaaaaaggct aagatacttt ggtcttcaga aacaggttga
     5641 gcataaaaat tataagaaga gctgaaccag atcacgatac tagaaacaaa gataatcgtt
     5701 cctgcttttt taacaaaaga cttgctgcgg tcataggttt gtcttaggac cgctgaccat
     5761 tgaggaaaat gatatgcggg caattccatg ataaaaggag ctgtatctcc agcaaacaaa
     5821 cgtgtttttt tcaagctgat tccagagaaa ataattgcag tcataccaag aaaataggca
     5881 gaaggagcta cccaagattg atgaggaaaa aaggcccctg ctactaaggc aataatcggc
     5941 aactttgcag aacaaggcat gaaggttgtg accatgatcg tcaaacgacg atcttgctcg
     6001 ttttcaatcg tgcgactggc catgacgcct ggcactccac atcctgtagc aatcagcata
     6061 ggaatgaagg attttcctga aagaccgaat ttcctgaaaa gtcgatccat gacaaaagcg
     6121 atcctcgcca tatatccgca gtcttccaga aagctcaagc ataaaaacaa tataatcaat
     6181 tgcggtagaa atcctaacac tgctcccacg cctgcgatga tgccgttcaa gatcagctcc
     6241 tgcatccatc ccgctacttg ccattcagct aacaatctgc caacatgttc tggtaaccat
     6301 gtaccaaaca atgtgtcatt gatccaatct gtccccattg ttcctactgt ttgaatagcc
     6361 agataataga tcagccacat cacaaatgcg aagatcggca aggctaacca acgattcgtt
     6421 gcaatctgat cgattttgtc actcatcgat aattggaaag aatcatttga cacaacacag
     6481 agtgtacata gttgggtaat aaattcataa cgttcattga ccagaatcgt ctcactatcg
     6541 tcgtccaata gtttctctgt taactggatc agttgctcga tctctttttg ctgagaaact
     6601 gctatctcgt aatcctctct taccttctga tctcgttcaa aatatttcat tgcataccag
     6661 cgtttcttgc cgctttgttc tcctagtaca tcttcaattt catgtaaagc tgcttctaaa
     6721 cgtggatcat atgtacaggg aacaggaata gaaggccgct tttttgcaga ctcctgaatc
     6781 ttttcgatta gtttttcgat tccttgcttt ttcaatacgc tgattggtaa aactggtaca
     6841 ccaagaccat aggaaagctt ttctagattg attttttttc cttctttttt gatgacatcc
     6901 atcatattca gaccaatgat cataggaatg tctaaatcca ataactgcgt agttaaataa
     6961 agatttcgtt ctaaattggt agcatcaata atgttgatga tcagttcagg ctgttcctga
     7021 accaaataat ctcttgcaat cacttcttct ggtgtataag gagacaaaga atagatgccg
     7081 ggtaggtcct gaatatgaat gttcggattt tttttcaacg atccttcttt tttttctact
     7141 gttacgcccg gccaattccc tacatattga ttcgaaccag tcaagagatt gaacaagcta
     7201 gttttcccgc tgtttggatt tccgactaac gcgatattca ttctttttcc tccctttgta
     7261 tcaagattag ttcggcctct gactttcgta acgtcagttc ataccctcgc actgtcagtt
     7321 cgattggatc tcccagaggg gctagttttc ggataactat ttttacattt cgcgtcaatc
     7381 ccatatccat taaccgtcgc ttcactgcgc cttgtccgtg gattgctacg acgatcccag
     7441 tctctcctgc ttttaattga tcaagagaag tccagctttc agaggaagca gtctttttat
     7501 tgacaaagat ttgacctagt atttcccgac ttactgccac tcgatgactt tttaccagta
     7561 aaatggcatt gttgcctgat aaattgacga cgacgatttt acttccggca acgatcccga
     7621 tattttgcaa atggcgtttt gttttttctt ctgtttcgat tcgttcgact tgataaacga
     7681 aattctgctt tgcctgcgct aaggtctgca tattgattcc tctcttgtga aataaatcat
     7741 gtattaaaat cattcattat atgttctaat tttcttacgt gttacgcaaa taaatgagaa
     7801 tcattctcac atagaatact ctcggtaatt gagaatgtca attatacttg tgatattatg
     7861 agcgaatctt tagtattgat agataaaaat gagaaaaaaa tatttcttca tagttttcca
     7921 caattttttc tctattaaat ttgctatttt cccacacgat acttgttttc agctcttttt
     7981 tcaaaaacac aaaacttagt attccacagt ttccacaaca caatatgtag tgtttgttgt
     8041 ttgacttttt tactaagagt tttatactat ctattataga taataagaat gtgttagagg
     8101 aggcactcac catgaacgta aaaatctttt ctaaaaataa ttgtatgcaa tgtaagatgg
     8161 tcaaacggtt tttaacagaa aatcaaattg cttttgaaga agtcaatatc gatgaacagc
     8221 ctgaagcagt agactggttg aaagcacaag gattccaaag tgttcctgtc attacttctg
     8281 atgcagaaac agttatcgga ttccgtcctg atcagttgcg taaacttgcc agctaacatg
     8341 actaaaagaa tcaaaacgtg atacatggat ttgaagggct tgagacagca ccagtttttg
     8401 tcgcaaactt ccaaatcctt ttttaaagct taaaaacaat gcaatgattt gcaatcaagc
     8461 atcatcaaat acgaaatgaa ggttgggcgt acgtatgagt cttaaaaatt tacaagatgt
     8521 cagttatttc aagctgaata atgaaatcaa tcggccagtc aatggtcaaa tccctttgaa
     8581 taaggataaa gaagctttag ttgccttttt tgaggaaaat gtcaaaccaa atacgatgac
     8641 ttttccatct attatggaaa aaatcaatta cttgatcgat caagaatata tagaagcaga
     8701 attcattcaa ttgtattcac catcatttat tgaaaagcta tatcaatttt tggacgagca
     8761 acatttttct ttcaaatctt ttatggctgc ttacaaattt tattctcaat atgcgttgaa
     8821 aaccaacgac ggttccgctt atctggaaac ttatgaagat cgagtagcct tcaatgcgct
     8881 ttactttgcg aacggggatg aagaattagc acttgctctt gcagacgaaa tgatccatca
     8941 acgatatcag ccagctacac cttctttctt gaatgctgga cgtaaacgtc ggggcgaatt
     9001 ggtgtcttgt ttcttgactc aagtcactga cgatatgaac tctatcgggc gctcaatcaa
     9061 ctctgctttg caattgtccc gtattggtgg cggcgtaggg attactttat caaatcttcg
     9121 tgaagccggc gctcctatca aaggatatga gggtgctgca agtggtgtcg ttccagtcat
     9181 gaaattattc gaagatagtt tcagctattc taatcaatta ggtcagcgtc aaggagctgg
     9241 cgtggtttat ttgaacgttt tccatccaga cattattgct ttcctttcag caaaaaaaga
     9301 aaatgcagat gaaaagattc gcgtaaaaac tctttctctt ggcgtgatcg tacctgataa
     9361 attttatgaa ttgacacgta aaaacgaaga tatgtattta tttagtccat atagtgtcga
     9421 aaaagaatat ggtgtcccat tctcttatgt aaatattaca gctgagtatg atcatctagt
     9481 tgcaaatcca aacattcgca aacaaaaaat caaagcgcgt gatcttgaaa atgaaatctc
     9541 aaaattacaa caagaatctg gctatcctta cgtaatcaat attgatacag cgaaccgcga
     9601 gaatccaatc gatggcaaga tcatcatgag taatttatgt tcagagattt tacaagttca
     9661 aacgccttct gtgattaacg gcaaacagga atatgaagta ttaggaacag atatctcatg
     9721 taacttaggc tcgacaaata tcgtgaattt gatgcaaagc cctaactttg gtcaatctgt
     9781 gcgtacgatg actcgtgcat tgacatttat tacagatgca tctgatatcg atgtcgtacc
     9841 accgatccaa aacggaaata agctgaatca tacgattgga ttaggtgcca tgggcttaca
     9901 cacttatctt gcaaaagaac aaatggaata tggctcagag gattcattag actttacaaa
     9961 tatttacttc atgctgttga attattggac acttgttgaa agcaacaata tcgctcgtga
    10021 aagaaaacaa gttttccata attttgaaaa atcagcttat gctgacggca cttatttcga
    10081 aaaatacgta actggagaat tccagccaaa atcagaaaaa gtcaaagcat tgtttgaagg
    10141 catttttatc ccaactgctg aagattggaa tgctttgaaa caagcagtaa tgaaagatgg
    10201 actgtatcat caaaatcgct tggcagtagc accaaatggc tcaatttcat atatcaacga
    10261 tacgagtgca agtattcatc ctatcactcg catgatcgaa gaacgccaag agaagaaaat
    10321 cggtaaaatt tattacccag cgccttatct atccaatgag acgattccgt attacacttc
    10381 tgcttatgat atggacatgc gtaaagtaat cgatgtttat gcaacggcac aacaacacgt
    10441 cgatcaaggc atgagtttga ctttattcat gcgttctgaa atcccagaag gcatttatga
    10501 atggaagaca acaacgaagc aaacgacacg tgatttgaat attttaagac attacgcttt
    10561 ccacaaagga atcaaatcca tttattacgt acgtaccttt actgatgatg cagaagaaat
    10621 cggaagcaat caatgtgaaa gctgcgtgat ctaatatcat agatagattc gcttattcat
    10681 attttaatta aaggagcatt ctcatgtcag aaacatatta tgaagcaata aactggaatg
    10741 aaattgaaga tatcattgat aaatccactt gggagaagct gacagagcaa ttttggctag
    10801 atacacgtat cccactttca aatgacctag atgattggcg tacattgtct caattggaaa
    10861 aagatacagt aggacatgta tttggcggtt tgacactgct agatactgtc caatctgaaa
    10921 gtggcatgga tcagttgcgt aaagatgtcc gcactcccca tgaagaagcc gttttgaaca
    10981 atattcaatt catggaatcc gttcatgcca aaagttattc ttctattttt agtacactga
    11041 atacgaaaaa agaaatcgaa gaaatttttg actggacaaa tacgaatcct tatctgcaaa
    11101 aaaaagctga gcgtatcaat gaaatctaca aacacggtac accgctagaa aagaaaattg
    11161 ccagcgtctt tttagaaaca ttcttgttct attcaggttt ttatactcct ctttattatt
    11221 taggaaacaa caaattggct aacgtagcag agatcatcaa actaatcatc cgagatgaat
    11281 ctgtacatgg aacctacatc ggttacaaat tccaattagg attcaacgag ttacctgaag
    11341 cagaacaaga aacgttaaaa gactggatgt acaatcttct ttatgagctt tacgaaaacg
    11401 aagaacgtta tacagaagaa ttatacgatc caatcggctg gacagaagaa gtcaagacat
    11461 tcctacgcta taatgccaac aaagcattga tgaacctagg gatggatcca ctctttccag
    11521 atactgccaa tgatgtcaac ccaatcgtaa tgaacgggat ttcaacaggc acaagcaacc
    11581 atgacttctt ctcacaagtc ggaaacggct atttgttagg tcatgtagaa gcgatgaaag
    11641 acgacgatta tttgattgga ttggaataag gatttatttt aattcaaaaa tttttcgaaa
    11701 aataaaaaga gtttagcgta cagatatttt aaatgtacac tgaactcttt tttatgctta
    11761 ttcacttgtt tcttccagca cttttggact gtctaacttt tccgaaacat gttccattct
    11821 tctcaataaa tagattttcc ggatatttaa tattatcgtc ttaatcactg catagacagg
    11881 tatgcaaatc agcatgccta atattcctgc gacacttcct gctccaatca ataccaagat
    11941 gatcgtcaaa ggatggatat tcattgattt cccaaataac aacggcttga tcaaatttcc
    12001 atctaattgt tggatcacta aaatcgacaa cgccatatac aaagcttgaa atggagagat
    12061 aaacaaaccg acaatgattg ctggtaccgc tccaataaaa gggccgacat acgggataat
    12121 attcgtgatt ccgcaaatga ccgcaagcaa caagctataa ggctgatcga atattctcat
    12181 tgccaaaaag ctcattacac caataatcaa agcatctaag atcgtactgc tgatataggc
    12241 agataatgtt tcgtttaatt cttttaccgt ttggcgtaac tctttacgaa tcgctttcgg
    12301 aaagaagtga gacaacgcat caataaattt gtgcccatcc ttgaacataa atagcaaaat
    12361 aaatggaacg gtaaataaca aaataaaaaa ttgcatcata aatgaaatga tttttgagac
    12421 acttgcagat aaactgacta atatgatatt gaacaaatta ctaagagata aatttgctga
    12481 tgctaattgt tcttccaaat tgaaattttt aaactcttcc cgctgcgcca attcatttaa
    12541 ccatttgctt gtttcatctg catacattgg caagctctgg gtcaattgaa ttgtctgttc
    12601 cattaactga ggcactacat tcatgacagt taaaacaact aaaatgatta cgaccaaaaa
    12661 cgtcaataaa aaaccgaaca ctctcgggat ccgatgcttt tcgagaaaaa caacgattgg
    12721 atcgaacata taatagataa aaccagcaac aagcaatggt aaaaaaattg ccgaaagcat
    12781 tttcaatatt ggactaaaaa tattcggcat ttgtaaaata aagtacacgc cgatgatcgt
    12841 gagtactagc tccactgtcc agaaaaataa ttttgattgt ttaaaacgtg attgcataca
    12901 tctcctccaa ggtcctttga tacttctatt ctatcattta acaaagagtt acgcgctgag
    12961 attttcattt gcttaaaaaa aacaaaaaaa ataaacatat tttaatgagt agacgagtac
    13021 ttaaacaaaa acacggtttg gagtagtgac aaaaattata ctgcagtccc tttttccaaa
    13081 taaacggtgt tcaaaagctt gcatcttcgt aataagccca gccaaacgaa aaatataagg
    13141 aactattttt atttggctgg gcttattact tgatgtagga catctatttt acaacctcag
    13201 atcatttatt gcgcaatact gactaaatgc aactttgtga tatttttgtg tacggacaac
    13261 tcctcgatca catcggcata agtgagccct tttggaagat caatcgtata gatatttttg
    13321 tacactcggt agtcatcaac gaattttacg tcaaaattca catcttcgat tacgatattt
    13381 ttctcttcaa aataatcggt aagaaaatct ttggtttctt ttctatggat aaattggatt
    13441 tctaactttt tagtcgtagg tacatggatc acgcgtttca ctactgtgag tgcaatagca
    13501 atcccgataa aactgatgat cgcaatggaa tagtaaccca tgccgatggc gatccctaat
    13561 ccagcaattg cccataaaga agcggcagtc gtaagtcccg tcaccgattg tttcgtgacg
    13621 atgatcgttc ccgcgcctaa gaaaccgaca ccactcacca cttgagcaat cagccttgct
    13681 tcatctgaac gaatcgttcc agcaagctgt ggatactcta aagcatctct taatgcacca
    13741 ctagcgatct caacttggat caatgcaatg atacatgctc ccatacaaac taaaatatgc
    13801 gtacgcatac ctgctggacg atttttatat tgtcgttcaa aaccgattgc tccgccaaat
    13861 agcatagcga tccctaaacg taaaataatc tctggaattg tcaataccat atcattcatc
    13921 taaacaccct ccagtccaat atatcatgtc tgaaaggagc agacaaaaaa agtgcaattt
    13981 ttacctctta cgaaaaaagg actgtgacaa aatttttgtc atagtccttt ttatgaataa
    14041 acggtgttca atcagctgac cctcggtatt actcaacaaa cggcaaaata tggggagcta
    14101 tttttccttt gtcttctcta atactcaggt caaaacgctg atttcacaac ctctttagcc
    14161 tactattgaa aattacaact tacttgctgc ttcttcatcg atgatcacaa caacattgtc
    14221 gtgattttgc aatacacttg ctggcaaatg attcgttaca ggtccttcaa tcatcccttt
    14281 gattgcatca gctttgcttt cgccaaatgc catcaagacg atttctttac ttttcataat
    14341 tgaaccgatt cccattgaaa cagcttttgt tggtacatct tctgctttat cgaagaatcg
    14401 tttgtttgca ttgattgttg attctgttaa gtcaactact gaagtcgttc cgtcaaatga
    14461 agcaccaggt tcattgaaac cgatatgtcc attttgcccg attcctaaga tttggatatc
    14521 gattggatgt gcatcgatga tttgatcata ctttttgcat gctgcttcca gatcttctgc
    14581 ttttccatct ggtacaaacg tttctttgaa tggtttttta tcaaataatt ggacatccat
    14641 gaaatgacgg tagctttgtt catctgaacc gcctagtcca acgtactcat ctaagtttac
    14701 agaagtcatt tcactgaaat ccaaatcgct tgaagtcatt tctttatata aagtaactgg
    14761 tgtgcttcct gttgccaatc ctaatacttt tgcacctttg ttcatacctt ctttgatgat
    14821 ttcaaatgct ttttttccgc cttcttcagc gttttttaca cgaatgattt ccatagtgat
    14881 tgctccttta tattttggta tagcccaatt atagcattct ttttttcttt ttacaataat
    14941 tagtatagac caaattgcat ttttttcatt ttcttgacaa taaataggaa tccgtgttag
    15001 gtttcataag atggttcaat caaacaatcc atgttgcatg aaaaccaagc aagtgattca
    15061 ctgtggacgc tttatgtctg cagttttttt atgaaaaagg agttattatg agtatactga
    15121 cattaaacaa cattacccag caatttggcg acaaaatcct ctatgaaggt gtcgatctgc
    15181 aattaaatgc tggcgaacat cttgggctga ttggacaaaa cggagccggt aaaagtacat
    15241 tgattaaaat catcactggt gagatcttac cagatgacgg acagatccat tggcaaaaaa
    15301 atattcacaa aggttacctc gatcaatatg tggaagtcga tgaaacatta acaatcgaag
    15361 aatttctaaa aactgcgtac gcaaaagaat acgaaaagga agaaaaaatt gcttttcttt
    15421 accaaacata tagcgagacc ttcgatgatt ccttgctgga aaaagctggg aaactccaaa
    15481 cggaattaga ccaaggagtg ttttatcaaa tcgacacctt agttgctgag atgagcagcg
    15541 ggttggggat cgatgtctta ggtttagatt cactgttgaa aaatctaagt ggtggacaac
    15601 gttcaaaggt gattttagca aaactacttt tagaaaaccc agatgttctg atcttagatg
    15661 aaccaaccaa tcacttagat gatcagcata tccaatggct gacgcagttt cttcaggatt
    15721 ttgacggtgc gtatatcgtg atttcccatg accaagaatt tcttgatcag atcaccaccc
    15781 atatcgcaga catcgagttt ggaaagatta ctaagtatac tggccatcta aaacaagcat
    15841 tgaaacaaaa ggaacaaaat cgcgaaagct atttgcgcca atatcatgct caacaaaaac
    15901 aaatcgaaaa gaccgaagct tatattcgaa aatacaaagc cggttcccga tcaacgatgg
    15961 caaaaagccg acaaaaacaa ttagataaaa tcgaacggct gacgcctcca gcttcagcaa
    16021 gtaaagctgt ctttgatttt ccattctcgc ctattgtcac gacattagca gtggaaacaa
    16081 ctgatttagt catcggatat gatcgaccgc tacttgcacc catcaatttg accatccgct
    16141 ttggtgaaaa tattgccatt cgaggcttca acgggattgg aaaatctact ttattaaaaa
    16201 cactgatcgg tgagattgaa aaaataagtg gcgatttcca cttcccagat aacacaaaaa
    16261 tcaattactt ttcacaagat ctgtactggg aaaatccatt agaaacacca ctacaatatt
    16321 taagcagtca atttccaaaa gcgactatca aagaattacg tcgccaacta gctaaagcag
    16381 ggttagttaa tcaattagca agtgaacctc tcactacatt aagtggtggg gaacaaacta
    16441 aggtgaaact tgcacagttg acaatgaacc aaggtaattt actgattctc gatgaaccga
    16501 cgaaccatat cgatcaagaa acgaaagaaa gcttacaaga cgggatacag aaatttccag
    16561 gaacagtaat catcgtctct catgaacaag aattttatca agatcttgtg caacgagtca
    16621 ttgagattga accaaaataa acgtttgatt gaatagttga aaaaaaggag ctgtgacaaa
    16681 agttttgtca caactccttc ttctgaataa atggtggcca attagctgac cttcggtatt
    16741 agctcaaaaa acggcaaaat atgaggagct atttttattt ggctattctt attacttgat
    16801 gcagaacagc ttttcacaac ctcttttcgt ctatttttta ttttcgagat ttctctttcc
    16861 tttaaaaaca actgtttgaa agaagaacgc acatccttga aaaacaagcc cgctaaccgt
    16921 tacacctaac cagccatact gctgccacat tgtcgtccct agcaatgaac cagccgcacc
    16981 tccaataaag tacataaaca taaataca
//
LOCUS       DACGEU010000060        16907 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.060, whole genome shotgun sequence.
ACCESSION   DACGEU010000060 DACGEU010000000
VERSION     DACGEU010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16907)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16907)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16907
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.060"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(418..3123)
                     /locus_tag="IXR40_001884"
     CDS             complement(418..3123)
                     /locus_tag="IXR40_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HAQ4361722.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(3429..4376)
                     /locus_tag="IXR40_001885"
     CDS             complement(3429..4376)
                     /locus_tag="IXR40_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HAQ4361723.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            4566..4835
                     /gene="rpsN"
                     /locus_tag="IXR40_001886"
     CDS             4566..4835
                     /gene="rpsN"
                     /locus_tag="IXR40_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HAQ4361724.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(5011..5373)
                     /locus_tag="IXR40_001887"
     CDS             complement(5011..5373)
                     /locus_tag="IXR40_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAQ4361725.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(5384..6505)
                     /locus_tag="IXR40_001888"
     CDS             complement(5384..6505)
                     /locus_tag="IXR40_001888"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HAQ4361726.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(6521..6871)
                     /locus_tag="IXR40_001889"
     CDS             complement(6521..6871)
                     /locus_tag="IXR40_001889"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HAQ4361727.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(7001..8512)
                     /locus_tag="IXR40_001890"
     CDS             complement(7001..8512)
                     /locus_tag="IXR40_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HAQ4361728.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(8834..10186)
                     /locus_tag="IXR40_001891"
     CDS             complement(8834..10186)
                     /locus_tag="IXR40_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HAQ4361729.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYLEKEKNKLIDAIKQNLEATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(10339..11415)
                     /locus_tag="IXR40_001892"
     CDS             complement(10339..11415)
                     /locus_tag="IXR40_001892"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HAQ4361730.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            11611..13356
                     /locus_tag="IXR40_001893"
     CDS             11611..13356
                     /locus_tag="IXR40_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HAQ4361731.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSFREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(13636..14073)
                     /locus_tag="IXR40_001894"
     CDS             complement(13636..14073)
                     /locus_tag="IXR40_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HAQ4361732.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(14057..15430)
                     /locus_tag="IXR40_001895"
     CDS             complement(14057..15430)
                     /locus_tag="IXR40_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361733.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(15752..16240)
                     /locus_tag="IXR40_001896"
     CDS             complement(15752..16240)
                     /locus_tag="IXR40_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4361734.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEAFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(16262..16864)
                     /locus_tag="IXR40_001897"
     CDS             complement(16262..16864)
                     /locus_tag="IXR40_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HAQ4361735.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT         4748 a         3614 c         3072 g         5473 t
ORIGIN      
        1 atttttttat gggctttttc tttgaattct ataataaaag gatagaactt gacttagaaa
       61 atcaagttct atcctttttg atatcttaac ttttggaaga gagatgtaag gctgctttct
      121 acccatcatt cttactactc gaagcatagc gcagttgtca caacctcttg ataaacggtg
      181 tttaaaagct tgcatctgcg gtaataagcc caaccaaatt aaaaacataa gaagctgttt
      241 ttatttggtc gttcttatta cttgatgcag agcagctttt ttacaacctc ttggtacacg
      301 gtgttcaatc agctgaccct cggtattagc tcaaaaaaac ggcaaaatat gaggaactat
      361 ttttccattt ttttctctaa tactcaggtc aaaacactga tttcacaacc tcttttttta
      421 atgaaaaata tggctctcat gcgccgcttc tttgaatttc gtcatttttt cttcgatgaa
      481 cggatagatt gccgttccta cgattccaaa gacaacaaac aaaccgatca tgatccagat
      541 tgctttcgta gcatttggcc aataaattcc tcctgcagat tcccgtaaca agtttaccgc
      601 atgagtaaat ggcaagaacg gattgatcat ttggaagaat ttccctgaga cttggatcgg
      661 atagttcccg cctccgccag agatcgacag tactaagatg ataatagcga tccctttacc
      721 gacattatcg aataatgcag ccaagacata gacgatcatc atgaacgcta aggcgatcaa
      781 gacagcaaat gacacgctgt agaccggatt ttggacatct actcctagta agaaaatatt
      841 ccctaatgta acgatcaagc tttgcgcaat cgccattgtc aaaaatgtca gcatacgagc
      901 aacgaattgt tctcgtttcg taaaattgtt tcggtctttc tttcctaaat agtattctgt
      961 cgtagcaaca cttgaaagaa gaacagcgcc gacccacaga catagtgcag tataaaacgg
     1021 ggtgctagct gaaccgttat ttgcgattgg ataaagcgca ttggtttgta gctcaacagg
     1081 ttgtgtaaag aagtcacttt cttttgttgc gtctagtttc aataatttga tgacttcgcc
     1141 tagatcgact tcttgttcgc cttttcggat cgcgtctgct gctttttgga taccagcttt
     1201 gatatttggc cagtcattgt tgatcaagtc cgcagcagcg ttcacagctg tttcgacttc
     1261 tggcattttt tcatttactg ttgtcaatgt accggtgatt tcatttttta gtgctggcca
     1321 atcattttgg ataaaatcag cggccaatcc taatttttgc tgaatgatcg gtaattcatt
     1381 gttgtatagg tctgcccctt cattgatgcc attgacgatg gtatccatat ttccattcag
     1441 cattgtattg gcatcatgga tttcttgtcc aattgcaggc atttcttttt gatatttttc
     1501 taaaattgcc actgcattcg ttacagttgc tttcgttgag ctgagaagcg aatcaaagtc
     1561 gatctggtcc gctttgctca gtgcgccttg tgcagtccca atcgtatcga tgacttggtc
     1621 tagtagagaa gtgacagtgg aactgatttg acctgtattg ataccagcaa tgatgccatt
     1681 gatattatta acaacggcat caatttgatc tagcaattca tcaatagcct tcgtgtcttc
     1741 attttgaaca gctgtgttca aagcagatag gcggttttgc agattgctta gcaagggttt
     1801 taattgattt agctgatcaa taattggctg taatttcgta tttccagcac ttgtttgcaa
     1861 tttagtcagg aactcgacca gtttatcgat tgcattttgt tgttgagata ttccgtcaat
     1921 aaagccgttc aatacattgc tgatgttttt cttttcatca tcagtcagct taccatcttc
     1981 aatagctgtt cttacagtat ctattaacga acctgtcgtt gttgccactt gtccaattga
     2041 cttcaatgta acatctacac tgtttgtgat gcttggtatc gcatctttca gctgagaggc
     2101 acctgatttt gtttggtttg ctagatcact tgcctgattt tctaaatttt tcacatctgg
     2161 caagatatct tgtacttgtt ggatgatcgt caagccttgt tttgcttcat cgattccttg
     2221 gttcattgtc tcttggatcg aagcaaaatc gccgtcgatc tctgctagtt gcttaccggc
     2281 attttggatc tctgggattt tttcttgcaa atcaaggatg atttttgctt gatctttcaa
     2341 ctcaggcatt ttgtcattca atgcaacgac tttttcaccc atctcatcta ctttagggat
     2401 gtaatccacg aattcatttg ctttattcag tttttccttg atttcaggta gttgactttg
     2461 taattcgagg acttgttttg tgtagccgtc gatcgtgtcc aaattttcat ctgttgataa
     2521 aatcatatct ttaactttat tgatacttac taggttcgta tcgatgtcgt aacctatctc
     2581 attgaatact ttcaataaag tcgaactggc tgttttgata aattcatttg tgatttgcga
     2641 ttggatcgaa cttgctcctt tatcggtgat tttcggtgca atcgcattga ttttttcatt
     2701 taccgtatat tcgatttttg gtttcttgat atcaccacta gtaaaactca gcagatcttc
     2761 tgagaaatcc tttggcaagt aaatacctgc gtaatacttt ccggaacgga ctccgtcttc
     2821 taattgttct tttgaatcaa cgaattgcca tcctaattgt ttatttttat gaagcgattc
     2881 gatgacttgc tccccaatgg ccacttcttt accttgaaac tctgctggct tgtctgcact
     2941 gtaaacagca attggcagct ctccagtatt tccatatgga tcccataatg ctttgatgtt
     3001 aaaccacgca tatagcgaag ggatgatcat gatcgcgatg atcagaagtg ttgcaatcgg
     3061 gtttttgaaa atccgtttcc agtcaagcaa atataatcga agcgtatttt tgattgactg
     3121 catagttctc ccccttcttc ttttttcagc tgaattactt taccatgtat ttcatacttt
     3181 tttcaatcgg cttttttcaa aaaagtcgaa tttttggaca tatcacggca attgtctcat
     3241 tgtaatctct tacatattga gaaataatta aggattacag cctttacttt atcatgaaat
     3301 aaaagggaaa gataatttta tgccaaagtt tttatctatt atacgtatac gcaaaaaagc
     3361 taaaacattt tttgtctttg cccctacaaa aatgtttcag cttttttcgt tttttattcc
     3421 tgtatttctt atttttcgaa tgacaggatg attttcccag caggaggatg tccttcaact
     3481 agctgatgtg cttggatgac atgcttaagt gaagcagaca gattcattga aataaaaaca
     3541 tgaaaggctc ctttttggta ggctttgatt atgccagcaa aggcttctgc atctagatat
     3601 tcctttcttg gaacaaacga ttcataaaag ccttcctttt tttgccgcaa atctagatct
     3661 gggaggtcat ttaatgcaac atacctgccg cctggtttca tgatctggat gccggtttct
     3721 cctttgatac ttcctttcgt cgcatcgatt acaaggtctg cctgatcagc aaattgcaga
     3781 cctggatttg ttttatcata agcagcaaat gctgaagctc ctaatttttt taccttttcc
     3841 tcatttttac tggatgcact ggttaagatt cggattccct tttcatggag aagctggatc
     3901 agacttgacc cgaccgcacc tgatgctcct agtatcatta cagtatctgt cggctggatt
     3961 tccgtcaaat ggttgattag attataagcc gtaattcctg gcgtgaccat tccggctgct
     4021 tcttcccaac tcattttatc tggaattttt gctacttttg ctgatggcaa cacgacttct
     4081 tctccgtaag tcccgccgac tgcatggaca gctactcgat cacctacatg aacagttgtg
     4141 acatctgaac caatctctgt cacaatacca gcgccatcat tacctggtac ataagggaat
     4201 ttcaatgttc gtatctcttt catttctcct aaacgcaagg caacatcata aggattcaca
     4261 ctgaatgctt ttatttctac acgaacatgt ccagaaccga cttctctggg atgagcatcg
     4321 atttcttcaa aaacatcttg tgcttctccg taaccgttaa ttgcaaatct tcgcatggtc
     4381 accatctccc tttttcttta agtttacgtt tatgccttta ttttgacaaa aaaaatgtct
     4441 tttcgttttg gcgcatgatt caaaacaaaa tagttgtctt ttttcgcgta acgtgttaaa
     4501 ttatttatct aaaagcgtaa agattacgat ttacgctaat aaaaaataat tggaggaatt
     4561 tgttgatggc taaaaaatca aagattgcca aagcaaaaaa acagcaagaa acgattgaac
     4621 gctatgctgc tttacgccag gaattaaaag cgcaaaaaga ttacgaaggc ttgcgtaaac
     4681 ttcctttaga tgctcgtcca gaacgattga aaaatcgtga tttaatcgat ggacgccctc
     4741 gcggatacat gcgtaaattc gggatgtccc gtataaaatt ccgtgaatta gcacataaag
     4801 gtttgattcc aggagtaaaa aaagccagct ggtaatccaa gtctggctgt aatgtaaagg
     4861 aggagggcgc atggaccact ccttggatca tcaaaaaaga tacgttcgct tcttctagca
     4921 gaaatgctgg tactagaagc agacgtatct ttttttacgc acagctggtc cttttttata
     4981 tgtaaaggct gcatggttac ttcgctatat ttatttagta acaggagtca gtgcttcgat
     5041 acccacacta attttcaatg ctcggtcaac ttctgccata atgggtcgat ccaaatggca
     5101 gaccttttct ttcaatcttg atttatcgat cgttctgatc tgctccaaca ggataacgga
     5161 gtctctttct attcctgttc cagtagcttt gatcccaatg tgagtcggaa gcttaggttt
     5221 agccattttt gccgttatgg ccgcaacaat gatcgtcggg ctaaaatggt tacctagatt
     5281 attttgaata accaaaactg ggcgtgttcc gccttgctcc gatcccacga ctggagaaag
     5341 atcagcaaaa taaatatctc ctctttttac cataggatcc tccttattct tgatattctc
     5401 ttggtatccg ctgtcctaat ccgcaagcca cttcatagtg gatcgtacct aattgatctg
     5461 ctatatcctg catagtgatt tctttgtctg catttttgcc gataagcgtc acttttgttc
     5521 cgacaggaaa ttcttgaggc aatcggatca tcagttgatc catacataca cgcccaatcg
     5581 tttcacagta gttcccttct accaatagag aaaaaccctg catctttcgt ggccagccat
     5641 ctgcataacc gatcggtatc gttccgatcc actctgcttc aggagtgata tatgtttctc
     5701 catagccgat tccttcacct gctgggagtt ttttgacttg aatcaattca gaaaccagct
     5761 caagtgctgg ctgcaatgga taaacttccg gtagtgcgtg cccagaggga ttaagtccgt
     5821 acattgctac tccataacga atcatattgc cgattgtttc atcatgccat aaagccgttg
     5881 cactattgct gacatgtaca tatcgaggaa gttcgggaag ttttttcagc acttctataa
     5941 agcgttcttt ttgcagattc caatatgtat catctgcctg atctgctgta gaaaaatggg
     6001 taaataaacc ttcccattct aatacacgac tttctttgat gaatgcagct gcctctttta
     6061 cttcttcagg tgtacaaaat ccgatacgac ccatcccagt gtctgctttt agatgaatcg
     6121 aaagaggcgt ctctagctta cttttctcta aaacagcagc tgctgcttgc aaccattccc
     6181 gtgtacctgc agttactgat aaatcatgag caacagctac agtcagtgcg tcgtaaggaa
     6241 ccatattcaa gataaggatg ggctgagtaa atccagcttc tctcaactcg actccttcat
     6301 ctaaatttga aacacaaaag cccgaagctc cacctgcaac tgctgcctca gctgtttcaa
     6361 tagctccatg accgtatccg ttcgctttta ctactgcaaa caattctttt ccttgcggaa
     6421 gtcttgcaac ttcatttgct acattttcag ttatagcttt tttatgtatc actgctttcg
     6481 ttgggcggtg ccaagcgaca accatcgttt ttccttcttt ctagtcttcc aaaataattt
     6541 gtgcaaaagc tgtttcattt gtatgagtaa tactgaccca tacattgcct tcatgaggtg
     6601 aacgcgtcac aacaggctga ccattttcat tttttaaaat ctcgacatct tgaaaggtaa
     6661 cttttccgat cccagttccc caagctttag agaaagcctc tttgcaagcg taacgcccgc
     6721 ctaaaaattc tacttggcga tgaaaaggca aggactggaa tagtttcatt tcatcagagg
     6781 tcaagattcg tgcaatgaat tttggttttt cttcgatcag ccgagtgatc ctaggaagtt
     6841 cgactgcatc gatcccaatt ccttttatca tatgcttttc tcttttcaat aaatttagaa
     6901 cactctcatt ctaccaaatt ataaccattt tgccacaaat aagtccacaa ataacaaaaa
     6961 tgaaagtttc tcttaaaaaa gagaaacttt cattttatgt ttaatcgtta tttgaacgga
     7021 ttacaaatcc gcgtttttta tcattgtgac gtttaccgcc atctttttgg ctgttattat
     7081 ttttgctata accgcctttt gatttgtttc cacgataatt accgccgtca cgacgattac
     7141 ggttgtttcc gccaccacgt ttgccatttt tattgtatcc ttttttctgc attggcaatg
     7201 ggcgttctgg tgtgatcttc actggcactg catcagctgg atcttttgct gtcgttttta
     7261 gcaaaagtgc aactaaatct tgtgcagaat attcttctaa taatttatct gctgtttgca
     7321 ggtatttatc tagaccattt tctgcaagtt ttgtttcgat ttgttcaact gcagcaccta
     7381 attgaccttt gaatgcttct ttttcggttg gtggacgtaa agtcgtcatc cgttttttcg
     7441 tcaagttttc aatcacatgc aagtagtcca tttcatttgg tgtaacgaaa gtcacagaca
     7501 taccgccttt tccggcacgg cctgtacgtc cgatacggtg aacgtagctt tctggatctt
     7561 gagggatatc atagttgtac acatgagtga cacctgaaat atctaatcca cgtgcagcaa
     7621 cgtctgtcgc tacaaggata tctaaatgac cgctcttaaa tgaacgcaat acgctcattc
     7681 gtttttgttg agacaaatcg ccatggattc cttctgcacg gtaaccgcgt gcttctaatc
     7741 cgcgtgccaa ttcgtctaca cggcgttttg tacgtccgaa gacgattgtt aattcaggtg
     7801 tttgaacatc aaacaagcga gtcatgatat cgaatttttc gtattctttt gcgcggacat
     7861 agtattgatc gatcaagtca gctgtcattt ctttcgcttt gatcttcaca tgatgtggat
     7921 ttttcatgaa tttaacgcca atattcttga tagctggcgg catcgttgct gagaaaagta
     7981 atgtttgtct ttgatcagga acttgtgaaa tgattttttc gatatcttcc aagaagccca
     8041 tattcaacat ttcatctgct tcatccaaaa ctaatgtttg aacggttcca agtttcaatg
     8101 tgtggcggtt aatgtggtca agcatacgtc ctggtgtacc cacaacgata tgtggacgat
     8161 ctttcaagcc acggatctga cggccaatat ctgctccgcc gtaaacggct tgtacacgta
     8221 cttttttgtc gcgccctaaa cgatataatt cttcttgtgt ttggatagct aattcacgtg
     8281 ttggtgcgat aactaaacct tgtaattcgt gacgatctgg atcgattttt tctaacattg
     8341 gtaatccaaa tgcagctgtt ttccctgtac ctgtctgtgc ttgtccaata acgtcttttc
     8401 cagctaatgc tagtggaatc gtttctgctt ggataggcgt tgcttcttca aaaccagcgc
     8461 gttcgactga tttcaacaat tctggtgata attctagttc tttaaatttc aaatgaatcc
     8521 tcctatatgg ttgttaactg aggatgtagc ttttttgcta ccccgtcgat ttgttcggtc
     8581 aaagtgtatt gtttcttttt gacagtggcc acgcacgttt ttatccattc ttagcccctg
     8641 tggcaccacc gaaaaatcac tttgcgaagt ttaggcatta gaaaagccaa acgggtcgcg
     8701 ttcagcttta tcattattat gacatctggc ttcaacaagt tgtttctatg gcaaaaccag
     8761 tccaatttct cttcatcttt cggcaatagg ttattctaac atagtttttc gttttctgca
     8821 agtttacaga tttttatttc atttgctgaa gttgttctac cacttcaaat aagcccatgc
     8881 tgttgctgcc ttttagcata atactatctg ttgcttcaag attttgtttg atagcatcaa
     8941 tcaatttatt cttttctttt tccaaataga acacaggtag ttgggggtat ttttggttca
     9001 attcttcttt tagtgcatgc atttgttccc cataaaggaa aatcatggcg aatttctcag
     9061 gatcgatatg ttcactcatt tgcgcatgca tatttaaaga ctctttccct aattccagca
     9121 tatctgctaa cacagcgatt ctgcgtcctt ttgttggcag atttttaaaa gtatctaata
     9181 ccagtcccat ggctgttgga tttgcattgt agacatcgct caaaatagct gcaccatttc
     9241 ctgccgttag ccattcggtt ctgttttgag tgatagaaac atgggcgagc ccttggcgta
     9301 tctcaggtat ggacagtcca aagaagcgcc cgatcgtata cgcaatcaaa gcattcgtta
     9361 cattataact tccaggcagc gggatcgtaa atgtttctcc ttctactaca aaatcggttt
     9421 gtgcttttcc ttttgctgtc acttccgcat gaacatcgcc atttccaata ccgaatgttg
     9481 tgactgtttg tactaatgtt gccgttaaag gtgtcagcaa cggttcatct gcgggcacaa
     9541 cgagtaatcc gtctgataca agtccgtcag tgatttccat tttggcttta gcgattcctt
     9601 ctcgcgaccc aagattttct atgtgtgctt caccgatcat tgtgattgct gcagcttttg
     9661 gttgagccat aagtgaaagt tccgtgattt cattggcgtg atccatgccc atttccaaaa
     9721 cgatcttttc tgtatcttgg ggcatgtgca aaatcgtgta aggaagacca atattattgt
     9781 tgtaatttcc ttgcgtctta tatgttttgt atttttcaga caagacagac gcggttagat
     9841 ctttcgtggt ggttttacca ttgcttcctg taattgcaac gacttctgcg cctacttttt
     9901 ccaagtaata ggttgccaat tgctgcatgg ctttcaaagg atctgctaca ggaataactg
     9961 gaaaattttt tggagcttgt tcaacaggca agctccaaaa tgaagcagat gctccgtttg
    10021 tgatcgcttg ctggataaat tcatgtccat ctcgcgtacc agcaagagga acgaataaac
    10081 ttccttcggt tatcttccgg ctgtcaaatt cgacattggt aatctttgtc agtgcagagc
    10141 attcgctgcc cacggcttgt gcaatttctt gtattgttag attcattgag atctctccta
    10201 aaaaaggttg tgaaaaaagc gtttggccta aacggcgggt tcgcatgact ctcacttcca
    10261 agtaaatttc tctattcgta tttagaagct agaatgaacg cggttacgca atcactccag
    10321 cctcttcttt atttctcttt attcattttt ttcaaaaaaa gattgacgct gatggtatcg
    10381 attcattcct aactggatca gttcttcaat caaatcaccg tatttcaagc ccatattttc
    10441 ccataagagt gggtacatac tgaactccgt aaatcctggc atagagttta attcattcag
    10501 gaataattca tttttatttg tcaaaaagaa atcgcaccgg ctcaatccgc ttccacctaa
    10561 catcgtgtaa gctaacttcg cgtactcttg cgctttttga taaacttctt ctggcacttc
    10621 ggctggaatc tgcatttcga ttttattatt gatatatttt gcttcataat catagaatgc
    10681 tacgtctttt acgacttcac caggcaaagt cgtccgaacg tcttcatttc ctaatacagc
    10741 aacttcgatt tcgcgcgctt caattccttg ttcaacgatt gctcgagaat catactgata
    10801 ggctgttgct aaagcatttt gcagctcttc tcggttttct gcttttgtaa tgccgacact
    10861 agaacccata ttcgccggtt tgacaaacat cggataaagc aaagaacctt cacattgatc
    10921 aaatactttt ttaggatttt ctttccattg attcttaagt actggtacat aaggaacttg
    10981 cggcacacca gcagcttgta aaatatactt ggtcatgatt ttatccatgg cacatgcact
    11041 ggtcaatacg cctgcgccga cataaggcat attcaatgtc tctaagaagc cttggatcgt
    11101 tccatcttcc ccgtttggcc catgtaaaac tggaaaaacg atggctcctt cttctttgat
    11161 ttcgcccgga ttgatcactt ttcctgtaaa gccttcctct gtctgtccac ttgggtccca
    11221 tgaaagatgc aagacatctt tgctggcagg tttttctgtt agtaatggac ctttgaccca
    11281 ttgtccttct tttgtaataa atacgagttg aacttggtaa taattataat aaatggcatt
    11341 taaaactgaa aatgcggaaa gaatggacac ttcatgctct gcgctgcgtc cgccatatag
    11401 taaagtaatc ttcaaaagat tgtcctcctg tattctaaat cgttcagtga tttactctca
    11461 tattttagca caaaacaaaa ataaacgaat aacttattta taaaaaaacg agccagcttc
    11521 taaaagaacg agcgtcattt attttttgtc agctagatta tttgtcccgt tttttataaa
    11581 aagttatgat aaagaaaagg agggatgatg atggcgcaaa caaatccacg cagccgcttg
    11641 gcagaaatca ttcgagtgtt catcaattac aatgtagtgc caaactttgt acagcaaaaa
    11701 aatcccgaac aggtaaaaaa agcctttgaa gaactaggcc ccaccttcat caagatagga
    11761 cagatgcttt cttttcgaga agatttgctt tcttctgcct tcactcaaac attcaaaaca
    11821 ttacaagata gtgtacctag cgacacattt tcaacggtca aaaagacgat cgaaacagaa
    11881 ctttctcttt cattatcaga tatattcgat gatttttcaa aatcgccttt tgcctctgct
    11941 tctatggggc aggctcatcg tgccaagctg aagaacggtg acgcggtagt cgttaagatc
    12001 caacacccta acatcgccga agagatccga cttgatcttc aactatttga acgagcgatc
    12061 cctttgatca aatacattcc tgaaactagc gtagttgatc taaaaggggt actccaagaa
    12121 gtaaaacgtt ccttgatcaa tgaaatggac ttcttaaaag aaagtcaaaa tggcgaacaa
    12181 ttctatcaaa agaacaatgg ctggaaagag atccgcagcc ccaagattta tgacgctttt
    12241 tgttcgaaaa aagtgatcgt gatggaagaa atgtctggta aaaacttgaa tcatttaatg
    12301 aacgccgaaa acaaaactga aacttttatc actggaattc aaaacaagca gctgaaacaa
    12361 gaagttgcaa agcttttagt tgagaacttt atgaaacagg tgtttgatga tggttttttc
    12421 catgctgatc ctcatccagg gaatctgcta ttccatgtac taacaaaaga agaacagaca
    12481 caagctagcc gaaaaactga aacagtccat gaaaaagagt tcggttcctt tgcttttcga
    12541 gcctccactt ctgcagaaga ccctgttgcg ccatatacca tcaactacat cgattttggt
    12601 atgatggggc atctttctgc aggacttagg caaaaactca cacaagccgt tttagcgctg
    12661 tatacgaaag atgcttatcg aatcgaaaaa gcggtccttc gactttgtca gcaagaaggc
    12721 tcgtttgatg aaagtcggtt ccaccaagaa ctgacaagtt ttcttgaaca gtattatgat
    12781 tctcctattg atgaaatcaa cttgcaagaa gtattcacac atgtcgtgac gatttgtcat
    12841 caaaataatc tgcagttcga tcgtgatatc acgcttttgc tgaaagcatt tgggacatta
    12901 gaaggggtga tccgcgtcct cgatcctgaa gtttccctca tggaagtcgc ttcgcctttt
    12961 gctcaacatt attttctcac tcatctggat gtagaagata cattgaaaca aagcggatta
    13021 gacttattgg aagggatgaa ggctgcgcct aagatccctc aacagctcca ccatctatta
    13081 gaaatgtgga cttcgggaca aggaaaagtc aatttggaat tgaaaaagca agacaaatta
    13141 ttgagcagga tcgaaagtat gatcaatcgg cttgttttcg gtatgatttt agctgcattg
    13201 atcgtagggt cctccctgct tgtccaagca gcacctgtag aaaacgcaga ggtcgtttcc
    13261 ttattaggga tatttacgta tgctattgcc gcattcgtca ttattttttt ggcaatcgat
    13321 gcattgatcc aaatgtataa gaagaggaaa aagtagaaaa aggttgtgac agaaagaatc
    13381 agcttcaaga aataagaagg ggttttacat aaattgtttc tcaaattttt gtgaaaattc
    13441 ggcttatttt tcgaagaggc tacttctgaa acaccgagaa taaaaaatgt gaaaaagctg
    13501 ttctgcaccc agtaataaga acaatcaaaa agggaacatg gaacacattt atcctgtttc
    13561 cctgttccct ttttgatgta ttcgagcata aataaaatac cttcgttacc tactatcttc
    13621 tgtacttggt aaaccttagt caattgcctt ttttaacgct tgacgaaaag acatatgatc
    13681 tttctccgta aagggttttg gaccctttgt ccttatgcca gcttttctta actttccact
    13741 atgataacgt tgttctagaa gcgtgccgat attcgcttcg tcaaattctt ttccagagtg
    13801 atggaacact cgcacaccct tcggcaatac aagtgaagct aaaccataat cttgcgtgat
    13861 caaaaagtca ttcttcttaa ccataccgac gattttataa tccgcactat cagctccgcg
    13921 gtctacgtag acgatttgga catgattagc gtattctttg gtcgtataat ggtccacact
    13981 ggtcacgata accacgtcaa gaccatagga ttctcctaat tttatgacat cttcttttac
    14041 tggagaacca tctccatcaa tgaatagcct cattcttttt cgccttcttc cataaatgat
    14101 aaacagttac taatccgctc agtaaaagac caacattgat ccattttgcc aagataagca
    14161 gttgtacact ttctatcggc actgattcat ggttcagcgt gatcaataat agatggattg
    14221 gctctcccat ttcttttgct aaaacaaaca aaagcgtcat caataaaaac tggtggatca
    14281 cactcccttt attttgagta gtatacttga caacgatccg gcgatccatt ggaatagctg
    14341 tatcagtttg ataatattcc ttatttagcc agctgcctgt tactacgtgc cagaaactaa
    14401 gcagaaagac acctatcgca aaaccatttg gaatcaagag gaccaataaa gaagaactca
    14461 gtccaagcaa ttgcatagcc aatggagacc atgttaaacg tttcaaaatc catggtccga
    14521 ctatttttgc tgcaatcaag cctgctgcat aaggcaaata cataaaaatc gaaagttttt
    14581 ctaatccgta cagtatgcca acataaaaac tgctaaataa aaaaaggaaa ttccctagca
    14641 ttccatttag aaaagtaaac agatttagcc agcttggcaa cttccattcc ttcttctggt
    14701 gtcctaaaac aaacacgaac aagatgaaca gcagcaagaa accataaata gcaagatcaa
    14761 aaagcctttc atcgaataac aatcgggcat ttctcaaaag aaacaataag ccaaagaata
    14821 tcaaaaataa aacaagctct cgcgtagcta ccagatttct tttgatgtct ttgaaatcca
    14881 gttcgtaacg cggataatga ctaaccgtat ggtaggccat gacgtaaaaa agtgtataaa
    14941 tagtaaagct tgctgcaatc tgagtcggtg caggcaactc aatcgcttga tacaggagaa
    15001 atagccagat agctgcaaat aagtactttt tcccatccat attgataaaa ccttgcgtct
    15061 tttcgtgaaa attgaccgtg gtattagcag gtacaagcca tgctgcactc agccctagca
    15121 aaacacttga aaaataaaat aaaggaaaat aaaatacgcc taatattcca agcaatgaac
    15181 cagcaccacc aatcagcaga gcgatcatca gcaacgtgta actatctaga ccaaatcgta
    15241 gactgttgac taaaaatagt ccagtcatcc gaaaggcata aaacagcgta aatggcaaaa
    15301 tcgtcagcca attatgcgag tctgttagtc ccaaaaataa aagataagga ataaaaataa
    15361 ccgtgttact taagataaag ggcgttgttt gtgtaaaatt acgcccaaat cgtttgagtt
    15421 tttcgaacat gacaatggct ccttaaacag tcttataact aatctgctct tcgattttag
    15481 cattaaaggg gaaataaacc aattttacag aatatattct tgtaaaaaaa aatacagaaa
    15541 gaagcataag cttctttctg catttttacg gtacttgatt actcaagcag acaagccctt
    15601 ctccacaaaa gtcttgcccg acacccctgc atccggcagg tgataaagat agaaatcaat
    15661 tatcctgtgc ctccaaaatc aattaggagc tctgtaaacc agagtccttc tcgacccgtc
    15721 gcataaattt actttaacac agttcctatg tttatgcgag agcttttttc attttataat
    15781 cgaccatttg aaatccttga ccgatatctg aaataagttc ttctgtaatc tcaaatcctt
    15841 catgcttata aacctcgatt gcttgatgat tcccctgatt cactcgcaaa aagatctctc
    15901 tttcctttgt ttgcgcagca agttcttcat accagcgaaa aactgaagaa gtcaatcctt
    15961 gaccacgtac tttatttagc aaatataatt tacttaaata aatttttcca tttatctctt
    16021 cataagcagt gtaaccgaca gtcttttctt cgctttttaa taaaaagtag gacacacctt
    16081 ctgtcagttc tttttgaatc tgtttttttg actgataagt tttcagcatg taatccactt
    16141 gtttttgacc aatgatcggc acaaaagctt ccggccatac ttcttgtatg actgccatca
    16201 gctcatccag ttcattttct gttactttta ttttttccat acacccacgt ccttttttac
    16261 attataaatg accttgcgct tgatggaata aaaagagcat gatcatgcta tacacaccca
    16321 ccgaccatgg tttcaagaaa atcacaatct gcataaattc cctaaaagat aatttcgtca
    16381 aaccagctac tagacagatc aagtcgtctg gcgcaaaggg aagcagcaag gtaacaacta
    16441 gtactttttt aatatctttc gtttttcttg tcagcaattc atcaaatttc tgatactttt
    16501 ttggcgataa aataagctgg acaaaggcta cgccatagta acggacaagc aaaaatccga
    16561 ttgcttcccc aatcactagg ccaatacaac tatataaaag cccaaatcca ttgccaaaca
    16621 tcagcatgcc cgctactgag gagatccctc ccggcaaaat aggaatgatc acttggatca
    16681 cttgcaacag aacaaatatc atcactgcat acttgccaaa ttgctggata aacgcttgca
    16741 aagacgtgct cgatcgaaaa atcccatgat gataagcata aagaatcaac acaaagaaaa
    16801 aaaacagacc aataatgggc atgatctgaa gacatttttg taaaactgat ccttttttag
    16861 acatctatat tccccacatc ttttttcatt tattaaaact gcctcct
//
LOCUS       DACGEU010000061        16794 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.061, whole genome shotgun sequence.
ACCESSION   DACGEU010000061 DACGEU010000000
VERSION     DACGEU010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16794)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16794)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16794
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.061"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            135..1475
                     /locus_tag="IXR40_001898"
     CDS             135..1475
                     /locus_tag="IXR40_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAQ4361736.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            1693..2136
                     /locus_tag="IXR40_001899"
     CDS             1693..2136
                     /locus_tag="IXR40_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HAQ4361737.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(2640..4058)
                     /gene="nhaC"
                     /locus_tag="IXR40_001900"
     CDS             complement(2640..4058)
                     /gene="nhaC"
                     /locus_tag="IXR40_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HAQ4361738.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPNLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(4461..5684)
                     /locus_tag="IXR40_001901"
     CDS             complement(4461..5684)
                     /locus_tag="IXR40_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HAQ4361739.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKERFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(5715..6554)
                     /locus_tag="IXR40_001902"
     CDS             complement(5715..6554)
                     /locus_tag="IXR40_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HAQ4361740.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETIVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNVALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDENNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(6571..7251)
                     /locus_tag="IXR40_001903"
     CDS             complement(6571..7251)
                     /locus_tag="IXR40_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4361741.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(7253..8326)
                     /locus_tag="IXR40_001904"
     CDS             complement(7253..8326)
                     /locus_tag="IXR40_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAQ4361742.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IVEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRKKALDYLIKS
                     GVKINILQKNDLDSRIKVIEGGR"
     gene            complement(8973..9644)
                     /locus_tag="IXR40_001905"
     CDS             complement(8973..9644)
                     /locus_tag="IXR40_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAQ4361743.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYLDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLN
                     KKTEK"
     gene            complement(9731..12409)
                     /gene="mgtA"
                     /locus_tag="IXR40_001906"
     CDS             complement(9731..12409)
                     /gene="mgtA"
                     /locus_tag="IXR40_001906"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HAQ4361744.1"
                     /translation="MSFGHKGEIEMEKKKDTQKIYAAFAGKTKQELFELFHASANGLT
                     EEQIERSRENYGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPG
                     DKDLFGVAIIFTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEE
                     IVCGDLVRLSAGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSY
                     ENLVFMGSNVISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKF
                     MSLMAPAVIVINGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGT
                     VIKNLNAIQNFGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQT
                     GLKNLLDVAIIDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGA
                     IEEMLNISKFIDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFS
                     VKDESDMVLIGYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLE
                     INELVTGEKISEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGIN
                     DAPAMKVADIGISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKAT
                     ASSNFGNMFSVLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKW
                     NASSIGEFMVYFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQRVIFIALFHAG
                     WFVESLWTQTLVLHALRTPKVPFIQSNATFAMFVITTLGIIVGSVLPFTSFGAELGLM
                     PLPGNYWLWLFATVIAYLALVTAVKKIYIRRFQELL"
     gene            13068..13505
                     /gene="ndk"
                     /locus_tag="IXR40_001907"
     CDS             13068..13505
                     /gene="ndk"
                     /locus_tag="IXR40_001907"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HAQ4361745.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAADAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(13527..14393)
                     /locus_tag="IXR40_001908"
     CDS             complement(13527..14393)
                     /locus_tag="IXR40_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAQ4361746.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICFKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLNLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLAHKERSTVIYETLMADYYQRLISAALGEEKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(14553..16646)
                     /locus_tag="IXR40_001909"
     CDS             complement(14553..16646)
                     /locus_tag="IXR40_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HAQ4361747.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVGKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKNNQ"
BASE COUNT         4855 a         3469 c         2954 g         5516 t
ORIGIN      
        1 ctattaaaat tcgcctaaaa gttttctgaa tagttgtaat tgtctgaaaa tttgttatca
       61 ttagtcattg ttaaatattg ctatttattc ttaatataaa ttttgattgt gaatttaaaa
      121 gaaagaggtc atttatggaa gataaaaaat tgaaaaaaca acttagctcc agacatatca
      181 ccatgttagc tttaggtgga gcaatcggtg caggtctatt taaaggaagt ggcgaagcga
      241 ttgggatcgc cggcccttct gtattgattg cttttttgat tggtgggctg attttatata
      301 tcgtgatgaa aggtctggga aaaatcgttt taagcggtgg cgacacgcat cacggattat
      361 ctggtttgat acgcccttat ctaggtgctc attctgctga ttttactgat tgggtctact
      421 ggtctatgtg gattatcaat atcatcgctg aagctgttgc agctgcttcc tttttgcagt
      481 tgtggttccc gcacattcca gcctgggtat ttgtttttat gttggctgtt ttaactacga
      541 tcatcaatct ttattcggta cggttattcg cagaaacaga atattggctg gcttttgcta
      601 aaatcagtgt cattatctta ctgatcattt ttgctactta tcttgtcggt cagcaaatgt
      661 tgggcacagg cgttttccct acccttcagc aattgactga ccatggtggg tttactcctc
      721 atggtatgaa gggaatcatc agttctttgc ttgtagttat ctattcttac ggcggttctg
      781 aactgattgc tatcacggta agcgaagcag atgatcctaa acgtgcgatt cctaaagcaa
      841 tcaaaggtgt catgggaaga atcatttcct tttacatcat tcctttgttt ttgcttttga
      901 ttctttttcc ttggaatact ttagcaggca cgaatgtcag tccttttgtg atggtatttg
      961 aaaaaatgaa tatcccattt gcagcggata tcgtcaattt tgtgattgtc cttgctttgt
     1021 tctcatctat caattcgggt gtgtatgcat cttcaagaat tttgttcttc cgtttgaagg
     1081 atcgaaaagg ttcctctaga aaactagctg ttttaaacaa gcatcaagta ccgcaacgtg
     1141 ctgttttatt ttgtaccagt gttctttatc ttggtgtagc tctttcttat tttgtcggtg
     1201 acaaattatt tggctatctg gcaggttccc tttcgtatac agtattattg atctggatca
     1261 ttatcagtgc ggcatccttt gtactggcac taagaaaagg aacattatgg gataaaggaa
     1321 tcagcttttt tgcattagct gtcttaggat tgattttcct tggtatcctg ttcacgaact
     1381 ccattggggt aactgtattg actggcctgc tttacctgtt catttatttc agttatcaaa
     1441 aaaagaatga tgcgttcgta ttgacgaatg aatgaaatcg atagaaaatt ttattttatt
     1501 tatgtggaat agatggagct attgaagaaa ggagttgtga caaaagtctt gttgcaactc
     1561 ctttttccga ataaacagtc tcatgacctc ttggtaaacg gtgttcaaaa accctctgtg
     1621 caaaataatt gattgttctc catgctcatg acatgataga agaaaggaat gaaaaaaagg
     1681 agtttgtttt aaatgaaaaa gtattggaag tttttgttga tgatcggtgt ttcaacggta
     1741 gttatgtttg gtatgatgta cttgaatgtc tatgcgctcg atcatatctt cttcagtcgt
     1801 acacgagtat tcatggcgtt gatgatgggt gcagtcatgg cagtcatcat gctgttgttc
     1861 atgtggaaaa tgtatgaaaa caaaaagata aatgttatga tcttagccgc tagtcttctt
     1921 gtttttgccg gttccttgtt tatggtacga agccaaacta ctgtcaacga cacagcttgg
     1981 atgaaggcca tgattcctca tcattctatc gctatcctgg caagtaaacg agctgattta
     2041 aaagatcctg aagtaaaaaa attagcggaa gaaatcattc aggcacaaga agaagagatc
     2101 gacaaaatga aaaaaatgat caaagaaatg gaatgaccat tatccgtcca aataaaaaaa
     2161 gaggatgttc cagaagttat cagcttcaag aaataagaag aagctacttc tggaacgccg
     2221 tgaataaggg gttgtgaaaa agctgccctg catcaagtaa taagaacagc caaacaaaaa
     2281 tagcttctcc tatttttcgt ttggttaggc ttattaccgc agatgcaagc ttttgaacac
     2341 cgtttattaa gaggttgtaa aatcagcgtt ctgacctgag tattagagag acaaatggaa
     2401 aaatagttcc tcatattttg ccattttttg agctaatacc gagggtcagc tgattgaaca
     2461 ccgtttatcg agaggttgtg aaaaagtcgc ttagtttcgc gtattaagaa aaattttgtg
     2521 aaatggcttt ccacattttt gtataaattt ggcttaatac cgagaaactg gcttttgaat
     2581 accgtttatt cgtaaaaggg attgtgacaa aagtcttgtc acaatccctt tttatgtttt
     2641 tattgttcta attgcgctgt cttgcttact gcttcttgcg gtttcacaaa tttttttgag
     2701 attccccaac ctgtgaaggc actgaccatc gaaaacacag gagaaagcaa actgaaaaat
     2761 acgaatggca agtaagtgag tgtaggaata ccaaatgtac ttgctacgaa acttccggca
     2821 attccccaag gcactaagta gttgattact gttccaccat cttctagcgt tctacctaat
     2881 acagttggat caaatcctgc tttttcataa gtttctttaa atgcattacc aggcagaata
     2941 acagatagga attgttcacc aataaaaata tttactccga tacttgtcat caatgttgta
     3001 aaaatcaaat ttggtgtgtt cgtcatcttt cttgatactc gttccatcac ggttgagatc
     3061 aagccaaatt cgatcaacaa tccacctaat gacaaagtta gaataatcaa tgacacagta
     3121 ggcatcatac tttcgattcc tccgcggcta agcagtgaat cgatttgttg gtttccagta
     3181 tttgaaacaa accctgattc gatgacccca gccaacttcg ttaaggaagt ttgtgggttt
     3241 tgaataaaaa tcattcctac tgctacagcg atattcaaca aaatcgttaa aattgccggc
     3301 acctttttcc atgcacacag taacattaaa aataaaggaa tcagtgacca gattgaaata
     3361 gtaaagtttg cttctagaac atcagtcact tcacgaatag atgaaagact tgcggcttta
     3421 cttgtgtgtc ctaaaatcat gaataaaaag aaagaaacaa caaatgccgg gacagttgac
     3481 cacatcatat gcttgatgtg tttgaacaaa tcggcatcaa caatagctgc tgctagattt
     3541 gttgattcgg ataatggaga catcttatct ccaaaaacgg cacctgaaac aatagctcca
     3601 acaaccagcg ctggatttaa gcctagtgtt gtcccaatac cgaaaaatgc aatcccaatc
     3661 gttgacataa cagtaaaggc actccctaca gcgctaccta cgattgcaca cacaacaaat
     3721 acagaaggga caaaccactg gacactgatc aatttgaacc caatgaccat tagagttgga
     3781 atgatccctg cttgtatcca tacagcaatc aatgaaccga ctaaaataaa aataaagatt
     3841 gggatgattc ctggtttgat gccattgatg attccttcgt gcagccaatc tgtcgggtat
     3901 ctttttatca ctgcatacaa catgaccatt ccgatcgctg ctaagatcgt gatattaggt
     3961 gagaccttta atccgacaac gccaatcgca atgcctaaaa caataaccat taatacaagt
     4021 gttgcttcta aaaaacttgg tgttcctttt tttcccatga taatctctcc ttttttagtt
     4081 gttcttatgt tctaaaaaag ttaagatatc ggattactcc gccgcaattc atccgcgatt
     4141 cctcctttat aaaaataaaa agacctgttt taaactaagg acgaatgact ccgcggtacc
     4201 accttaatta aaaacagatc tgtttttcac tttcaaactt ttattcaaat gtatggactt
     4261 tccatgtaat tcgtcaatta ggcttgatcg gttcacagcg accaccgact ttctgaacaa
     4321 aacacctaac cgctactgcg tgaaaagttg acttgtacga agtttacctt ccataagatc
     4381 atttgtcaat gaaaaagaaa atattttttc atttttctga aaattatttt tataactttc
     4441 acacacaaga ttatttttta ctagaaagta gcgccctctt gtttttttct tgctactatt
     4501 tcttgatgtt cttgcttgat tctttctaat agctttggct ctttcaacag atcaagagct
     4561 gtattggcga gtagttctgc tgcaatcgca atagaagcaa ggcctttgtc acttttagca
     4621 gcagctttga attcttctgt gtgtccggca atatatgtct cagagattgc taccgtaggc
     4681 tggattgttg gtatgacttg gctgacattt cctacatcag aagaaccgag acttgttctt
     4741 tgttccgttt ctatttcttc atctggaaca cctgcttctt ttgcatgctg gaagaataag
     4801 tcatcaaaag aaggagtaac gatgacatca tcaactgcat tttggaacaa tccaaactca
     4861 aaagtcgtgc ccgtacttat cgcagcacct cgtacgatat tttccacttt ttcatatact
     4921 ttatctaatg tttgccgatt tcctgcacgt aaatagaaac gtccagcagc gtaatctgga
     4981 atgacgttgg cagctactcc tccgtctgta atgatcccat ggatattgac atcttttggc
     5041 aattgcaagc gtagagcgtt gattccatta aacacttgga tcaatgcttc caaagcattt
     5101 actccttttt caggtgctgc tgctgcatgg gaagcgacac cgtaaaattt gatgtcgact
     5161 ggatcattcg ctaaagattc tgtcgttttc ccataacgaa aagctggatg gacgcataac
     5221 gctacatcga catcctcaaa aaaaccttct cgaacaaagc tgcctttagc tgatccgttc
     5281 tcgccccctt cttcccctgg ggtgccatat acacggattt ctccaccagt ttcatcaatg
     5341 aattgcttca ctatgctggc ggctaatacg gagtaagtac caaacaaatt atgcccgcat
     5401 gcatgaccaa tacctggtaa agcatcgaat tctgccaaaa aggcaattgt gggaccgggt
     5461 ttattggaaa tataacgtgc atcaaaggct gttcggtgtc cagctacttc tttttctacc
     5521 caaaaccttt ctttttctaa ttgtttaatc aacgctgctg aggaataaaa ctcatagtta
     5581 cttacttcag gatgttcgtg gatatctaga gcaagtgctt gatattctgg taaacgatat
     5641 tggattagat ccttcaattg gtttgttgag attgttgttg tcataaaaaa ttcctcctat
     5701 gctagtcatt tttcttattt tctcccgaat gtttcccatg caggcacgct tgatcctttt
     5761 gatgttttct cgattacttt gactgtgtct tctgtttgat aagcgtctac tattttttga
     5821 tacgttttat tgttttcatc ttcttttctt gcaacgatga tattcacata aggacgtgca
     5881 tggtcatcca ctggttctaa gaagatggca tcagaagcag gattaaatcc agcatctaca
     5941 gctacaccgc tattgatcac tgaaatgtct acatctgaca aagcacgtgc tgtttgggaa
     6001 gcatctaatt cagaaatgtc tagatttttt ctattctcgg taatatcaga aacagtgggc
     6061 gcttgtcctt ttgccttatc cactttgatc aatccagcag tttgcaataa cagaagagct
     6121 ctgccgccat ttgtaacatc attagggatt gctacttttg ctccgtcttt gatatcagct
     6181 acatccttca aagtgttaga ataaattccc agcggtgcat tgacagtatt tccgatcgat
     6241 actaaatcag ttccgtgttc tttattgtaa ttgtctaaaa agaattgatg ttggaaagaa
     6301 ttcaaatcaa tcgatccatc tgctaaagcc acatttggtt gattgtaatc tgtaaatttc
     6361 acgtattcca aattaatgtt ctcctttttc aaacggtctt tcacgttgtc ccatacatct
     6421 gtatcttctc caataatccc tagttttacg atagtttctt ttttgtcagt tgtatctgct
     6481 tttccttggc tacaccctgc caaccaaata attgctacaa atgtaatgac tacaaaacga
     6541 ataatttttt tcattttttc tcctccactt tcaatgtgta atttttttaa tcagttgatt
     6601 actgataaat tgacttaaaa aaactaagat tagaatcaat aatgtagcca caatcgttac
     6661 atctgtttgg aatcgattat accctctcga tatagcaaga ttccctaatc cgcctgcacc
     6721 tactgctcca gccatggtag tcagtccgat cacgttgatg atagtcaacg ccgagacccg
     6781 aatgatacca ggcaaacctt ctaacaaata cacacgtaaa atgataccga ttggactggt
     6841 tcccatcgct tctgccgctt cgatcacccc aggatcaact tctagcagtg cgttctcgat
     6901 ttgacgagca aaaaacggaa caactccaaa aatcaatggc actaaagctg ctttcgcacc
     6961 aatcgtcgtt ccaactaaga aacgagtagt caatgctaaa agagaaagca agataatgaa
     7021 agggatggaa cgaatgatat tgatcagctt atcaagtatt tcaaatagca gacggttagc
     7081 tagtaatcca ttagggcgtg tcactactaa cgtcacacct aagatgattc caatcatccc
     7141 gccaatgaat gctgtccaaa aagacatata tagtgtttgc ttcgtcgctt cgacaaattc
     7201 atccggaatc aaataaacat tgggcaaata tgttttaaag aaatcagtca ttttatcttc
     7261 ctccttcgat cactttgata cgactatcta aatcgttttt ttgtaaaata tttattttta
     7321 caccagattt gatcaaataa tccaatgctt ttttccgctg tttggtttct ccagctaaag
     7381 taacgatcaa actccctaac ggcgtttctt gtaataactc tacattgcca tataaaatat
     7441 tcgctgttac ttgatatttg ctgtacagat gagcgattag aggttcgttc gtctgatttc
     7501 caatataact taattccacc agccatttat tggcgatctg atcggcaaaa gcagaatggg
     7561 caatgatcgt ttctaatgct tggtcaagat gagtagctgt tcgaataaaa tctttggtca
     7621 attcttcttc aggattgctg aagatctgga tgctgctacc tttttcaacg attcttccat
     7681 cttccataac cgctaccttg ttgcagattt ctttgacaac ttgcatctca tgagtgatca
     7741 ggacgattgt taaacctaac tggcgattca atttttttaa caatgcaagg atctgaaggg
     7801 tcgttttcgg atcaagtgca ctggttgctt catcacataa taatacctta ggttcattcg
     7861 ccaaagctcg tgcgattgct actcgttgtt tttgtccccc cgacagttgt ttaggataag
     7921 cagatgcttt ttcttccaaa ccgacaagtt ccagtagttc attcactttt tgacgacgtt
     7981 cctgtttcga ttttccagaa tactttaaag aaaaatcaac gttgtcaaaa atagttcggc
     8041 tttccattag attgaaatgc tgaaagatca taccgatggc ctttctttct tttcgcaatt
     8101 ctttgggaga gagctgactc agattcgtct gattgacaat gacttctcct gctgttggtt
     8161 tctgcagcaa attcatcaca cgaactaacg tacttttccc tgcacctgag taaccgacga
     8221 ttccataaac atcgcctttt tcaatcgtta aatctacaga atctactgcc tgtatctctt
     8281 tttctttttg tttgaaacat acagaaacat ctcgcaattc aatcattaaa attcctcctt
     8341 atctaaaaaa agcgtcctca agaaaatgaa aatgtcattt tcttgaggac gcttttttgc
     8401 gtgttaccac ctcatgttca agctgtgttc acacacaact cctcttcaag tacgatcata
     8461 ctctagcaag atatcggtcg cagccgtcat cgccttacat ctatgctcgg gatgaattgc
     8521 tcgatggcca ttttccaata gtcgttcctt gcttcttctc agctaccgaa gctctctgtc
     8581 aaaggttctt ctatcgtact taccatttca atgcaaataa tattcaaaaa aaaagtcctt
     8641 ttactaacat aaactatgtc agtaaaagga cgacgtatcg cggtaccacc ttttttcgga
     8701 agtttccttc cctcaagccc aacatctcaa aaagagagat tggcgttcgt tttaacggtc
     8761 gaacagttcc gaatttgcct acttatcgac aaattattct ccaaggccat tttcagcttt
     8821 tcttacttga ctcttctcac cagccagagc ctctctgcaa agtttccaaa cttactttcc
     8881 ttttcaacga aatcgatatt ttgttgttgg gattaatcta catgaggaaa actgaaaagt
     8941 caagtacgaa attcaaatta ttttttctat atttattttt ctgttttttt atttaacatt
     9001 tcaataacag ttcgaagatc ttttccttcc gcaagaagtt tcaatttttc cttttcttcg
     9061 acggtataat ttcggacaaa actggaatca ggtatcaaaa caacgcctaa tcctgctcgt
     9121 gaagcagctg ttgctcctac taaagaatct tccactgcaa aggctgaact agcttctaat
     9181 cctgttcgtt ccaaagctgt cagataagga atcggtgaag gcttgttctc cgacacttcg
     9241 tctccgaatg taaacgtgtc caagtaatca gctaatttaa agtgatccaa gatatctgtt
     9301 gctcttttcg taacagtggt cgtagcaatg cctagtttca tatgacgttc ttttaagtct
     9361 gccaatattt cttttgcata tggttttaag tggatggctc cgcttgtcag ctgttgataa
     9421 aaatattctt cacgcttcgc tcggacttcc tgtacttttt cagggctacc tgctgctttc
     9481 actaaaatat caaaactttg tttccagttt tttccgcccc aagcgtcaac gatttctttt
     9541 gggatatgga tatcaaattg ctgaaatccc caaagccagc catcacgata cgttttttct
     9601 gtgtcaacta acaaaccatc taaatcaaat attgcacctt tcatctatac attaatcctt
     9661 tccaaaacaa tacacatagt ttagcacgac tggtccaaaa agaacagaag caaagaacca
     9721 gccttctcgt ttataagagt tcttggaatc gacggatata gattttcttc acagctgtca
     9781 caagcgccag ataagcgatg actgtagcaa ataaccataa ccagtaattg ccaggaagtg
     9841 gcatcaagcc taattcagca ccaaaacttg taaaaggaag gacagaaccg acaataattc
     9901 ctaatgtagt gataacaaac atggcaaatg ttgcgttgct ttggataaat ggtactttcg
     9961 gtgtacgcag tgcatggagc actaaggttt gtgtccatag tgattcgaca aaccatcctg
    10021 catggaataa tgcgatgaaa atcactcgct gtgaactatc caatgtatgg aaacttccgc
    10081 ccactacagc aggacaaata acaaaataca tcaacaagta agtagtaata tcaaatatcg
    10141 aacttgttgg accaaagtaa accatgaatt ccccaatact agatgcattc catttttttg
    10201 gctcgtccaa atattcttta tccatccgat cccatggcaa ggaaatgcag gaaacatcat
    10261 agatcagatt caaaaacaaa agttgtaaag gcagcattgg taaaaatggc aggaacgtac
    10321 ttgcaatcag cacggaaaac atattgccaa aattagaact tgctgtagcc ttgatatatt
    10381 tcatgatatt cccaaaagtt tctcgtccag aaagaaggcc tctttccaaa atcgtcaaat
    10441 ctttttctaa aaggatcacg tctgcagatt ctttcgcaat atccacagct gtatctacag
    10501 aaataccgat atcagccact ttcattgcag gagcgtcatt gataccatct cctaaaaatc
    10561 cgacagtatg accattttta cgtaaagctg tcgtcaaacg tgctttttgc tgaggattca
    10621 attttacgaa tacttcatgg tcttcagcta cttgtgctaa ttcatgatca ctcatttccg
    10681 agattttctc accggtaacc aattcattga tctctagacc tacttgacgg cacactgaac
    10741 gtgtaactaa ttcgttgtcc ccagtcagaa cttttacagc tacaccatgt tctttcagag
    10801 ctttcaacgc ttgtttcgtt gtttcttttg gtggatcaag gaaagcaaga taaccaatca
    10861 aaaccatgtc tgactcatct ttgactgaaa attctccaac gacgcttgga ttggtctttt
    10921 gtgcgacacc aatcactcgt aagccatctt cattaagtga ctgtactttt gcaagtacgg
    10981 cttcttttcg ttcttttgtt aatggtgtaa cagtaccgcc aagatcaata aatttagaaa
    11041 tgttcagcat ttcttcaatc gcaccttttg tgatcatttg tgttttacca gctggatcag
    11101 caaccacaac actcatacga cgacgttcaa aatcaaaagg aatttcatcc actttttgat
    11161 aattgatctt atctgtatct aaagtttctg ttgcttcatc aatgatagcc acatctaaca
    11221 aatttttcag ccctgtttga tagtagctat ttagatacgc atggcgcaaa acacgatcat
    11281 cttcatttcc ttcacaatcc atatgatatt caagaatgat tttatcttgt gtcaatgtcc
    11341 ccgttttatc cgtacataac acatcgattg caccaaagtt ctggatggca ttcaaatttt
    11401 tgatcactgt tccttttttg gccatcacac ttgctccttt gaccaaattc gtcgtaacga
    11461 tcattggaag catttcaggt gttagaccaa ctgctacaga tagtccaaaa agaaaagctt
    11521 ctagccaatc cccttttgta agcccattga tgacgataac tgctggagcc atcaatgaca
    11581 taaatttgat cagtagcatg gatgttttat ggatgcctaa ttcaaagctt gattgaattg
    11641 gtttttcaga tagcgtttct gctacatgac caaatagtgt ttcatttcca acagaaacaa
    11701 tgattccttc cgcacttcca ctgatgacat tacttcccat aaagacaaga ttttcgtaac
    11761 ttgtttcgct ttgctgatcg tcttcacata ctttcgcatg cttttctact ggatagcttt
    11821 cccctgtcaa tgctgcttgg gaaatgaata aatcctttgc ggacaataaa cgcatatccg
    11881 ctggtatcat atcccctgct gaaagccgaa caagatctcc acagacgatt tcttccatag
    11941 gaatctctgt gtactttcca ttacgtttta cagctgccgt tactttcaca agtgatttca
    12001 gtttttcagc cgcttgattg gaacgtacgg actgaatcaa cgtcattgtc ccgctgacga
    12061 taaccatagt gaagataatg gctacaccga aaagatcttt atctccagga gctgctaata
    12121 catattccgt gatgaatgaa ataattccta atgcgatcaa cactaatgta aatggcgtga
    12181 tgtatgcttt caatatttct acaatgaatg gtgttttttt gccatatgaa atcgcatttt
    12241 caccgtaatt ttctcttgaa cgttcgattt gttcttctgt caatccattt gctgatgcat
    12301 ggaatagttc aaataattct tgtttcgttt ttccagcaaa agctgcatag attttttgtg
    12361 tatctttctt tttttccatc tcaatctctc ctttgtgtcc aaaagacagc tgttctcgct
    12421 gcttttggtc tttagctatt catcggatcg atagagaaaa aactgaaagg ggctgagaac
    12481 agatagataa tagccctggc ctttcctcta gatccttgtt tttcgaatga ctgtcatcca
    12541 tttgttctca tctcctttac taagtaattt taattcatga cttccaatca tttttcgaat
    12601 agttattttt ccaattagac cacctccttt ttatttttca ccgatgggga tttgcggcaa
    12661 caaaaaaacc tctcgccaaa tactcagcga aaggtttgaa aaagcatatt aaaaaaagct
    12721 tctcagatct catcgttgag ttttgacact gtacaacgta aaaagcagat acctgctttt
    12781 agctacctta tgaaaagcct tatctcgaca attcctgttc tacccattgg cgtctctcga
    12841 cgtttttggg cagtagccta tgtttgtata ggagcctcac ctaacaaatc ttattcggtt
    12901 ttccttcgtt aatataacaa ctaaaaaaga ggatgtcaaa tcaattttcc atgtttttca
    12961 tacttttttt aaaatacaca cgttatattc ctgtctcacg cggttttatt tgtctcattt
    13021 tccacctccc gctataatag aaatatagta ggaaacgagg tgctgttatg gaaagaacac
    13081 ttgttattat caagccagac ggcgtgagac gccatttagt cggaagcatc atccaacgtt
    13141 ttgaagcaaa gggactggcc attgctgaaa tgaagtttga aactatgact cctgaattag
    13201 caaaagaaca ttatcagcac ttgactgagc gcagtttttt tgatgaactg atcgattaca
    13261 tgacttccgg tcctgtcgtt tatcttgtgc tggtcggcga ggaagtgatc gatatcgtcc
    13321 gtaagatggt tggagcaaca aaagctgccg atgctgttcc aggtacgatc cgaggagact
    13381 acgcgctgcc ggggactgaa aacatcattc acgcttctga ttcccgtgat gctgcggtaa
    13441 aagagatcgc ccgctttttc ccgccattcg atataaacaa accgtctgaa aaagcggcga
    13501 agtgatacaa attctaaact gctggtctag ttgctgggtt cagcaatggc cagcagtttt
    13561 ttctctaagg acctccgttg attctttcct aacatatatt cgagcactgt gaagaattct
    13621 tggtagtctt tcgtcttttc ttcccctaaa gcagcagaaa tcaatctttg ataataatct
    13681 gccatcaatg tttcatagat cactgtactt ctttctttat gtgctaagct ccgtttcata
    13741 tcttcattca cactacgtgc ctttttcaac cgaccatttt ctatataaaa cgaagtcagg
    13801 ttcattaaaa aagtaaagag atactgctca tgattgttca actgtgctaa tcgtcgcatt
    13861 ctttttttga ttttcaaata attgttctca atgaaccgat cactgaatat ccaaggaaaa
    13921 tcagctagaa tagatagttc aaattgacca tagtctggta tctgcatcaa gtattcttca
    13981 atgattcggc attcataacg taaaaattca aattctgtct cagatacttc tgttttttcg
    14041 accatgtgaa gattcaaaac caaataatac agatcttctg ttttcttaaa atgcctacgg
    14101 ttattgctga tctctttata aggatcaaag ctgtcttctt gtacccgatc tagcattcgt
    14161 ctttttttct ttaactttat tggttcatcc agctggtttc gcatccattc atattctgca
    14221 agtgtcatgt tcattcgctc taaaaatgat ctcaatgtta caaatgacat ttttttcact
    14281 gaatttgtct caatcccgac tagagaagtc ttaaaacaga ttccttccgc taattgggac
    14341 tgtgtcaact tcttgttgac tcgaagtttc ttgatcaatt caccatcata cataatagtt
    14401 ctccttttta atttaaattt ttccacattc aataaataga tacgttaaaa aggaaaaata
    14461 cacgaaaaaa ataaaaaaat gtttttttca taaaaaatac caaccttcaa gcattagaat
    14521 gttgtctaac tactgaaggt tggtttgatt gtttattgat tatttttttg ctgttcaacg
    14581 tctgttcttg ttactggata taagttggtt gttgttttat taccattttt tgaaaagaca
    14641 cttgtcgaat gttcgccttt ttgcttttcg attgcttcat tacgttccgc ttcattttta
    14701 tagtcatatt ttttcggatc aatcgtctca aatccgtttg gcacataaaa ccgcaagaga
    14761 ttttcctgat tcagcttatc tgaaagactt aacgcagtct tgactttttc ctgatctttg
    14821 gagatttcct catcgattcc tgctgctttc gtatcgatga tttctcctgt ctgattattg
    14881 taagcttttc ctcctaggac ggtgtatttg ggtgtcacaa agttcccatt tcgaaaagca
    14941 actacttgat catgctgaga agataataag tctgtaccaa aatgaagata atctttatca
    15001 tcgattccca atagatgtag taatgtcggc aaaacatcga tttctccacc gtattcatga
    15061 ttgactgtcc ctttagtata accaggcata tggatcatca atggcactcg ttgcatctgt
    15121 gcgttgtcaa attcatccca tgtatctgga tctttaccaa gagcgcttgc taaatcttta
    15181 ttatctgtat tcgagatccc aaaatgatcc ccgtaaatca caaagattga attttggtaa
    15241 ataccagatt ttttcaaata cgtaaaaaat tgttccaatg attgatccag ataatgtgcc
    15301 gttcgaacat aattatctac tgtgctattg ccagtattca aagatggaaa gtcgaaattc
    15361 ttgtcatccg tataataagg cgtgtggttg gttacggaaa gaaatttcgt gtaaaacggc
    15421 tgttgtagat gctcaagata ttgggcagat tctctgaata aatctttatc taatatccca
    15481 taacctaacg tttcgtcgga ttcatcaaaa taagatcgat caaagaaatt gtcataacct
    15541 aagtttttat atacatgatc tctattccaa aaactagcta cattcccatg gaaaacagcg
    15601 cttgtatagc cttgcttttg tccaaggatc gctggtgcgg cttgaaagac attgtctgac
    15661 ccaagttctg tgaataatga gccttgaggt aaaccaaatg tgccagtttc caacatattt
    15721 tcagcatcac ttgtctttcc ctgtcctact tcatgaaaga aattgtcaaa gctgatcgtt
    15781 gcttgattct ggaaaatact atttaaaaac ggtgtgactt cttgtccgtc taccttcata
    15841 ttaatcaaaa actgctggaa actttctaaa tggagaacga tcacattttt ccctttagcg
    15901 atcccaaatg tttcgggatt tggctctgca taatgtttct ttgtataatc taaaacttca
    15961 tcaatcccat tactgcttgc atgcgcgcga acactgctag tcattcctgt tttgattccg
    16021 tcataaatag tatacgcatc gattcctaga tatttgacaa tatatgaacg gtcaaatgtt
    16081 cgctgcagca attgtggacg gttggcttcg ctcagcgcta gatttcctga aaaaataagc
    16141 cctgaaagac aggtaacagc gatagccatc ggtttgccga cagggttgct tttgataggt
    16201 attttcttga ccttcaacca aaccagtagc ccaatgaaca cagcgatatc cagccagtag
    16261 atgacatcat ggggcttcat caaagaaaag gagcttcctg acaatccttg cgacactttc
    16321 gaaaagccta atacagattt gactgtaatg aaatctgtga attcccgata aaaaataata
    16381 ttcaagtaca acaaaagcgt atttaaaata tcaatgatca aaagaatagc taacgctggc
    16441 tttggctttt taatatacaa agaaaggcca aaaaacaata aggtagtcgc aattgggttg
    16501 atccacaaga taaagtactg gatcgtacct tccacaccta atgaaaaatc tgcatagtag
    16561 gcaatgatcg tcttcagcca gaaaaagaaa acagctgtca aaacgattgc taaacgattt
    16621 tggcacaatt ttttaagttg tgtcacgtat atcacttctc tctattcaca ttttttctta
    16681 ttttgctcct gaaaaatgaa aatttcctaa aaaagttgtt atcttaagat ttttttattc
    16741 tttctaaaga ttattccgtc cacttttcac agcataaaac cgctgcgatg taag
//
LOCUS       DACGEU010000062        16211 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.062, whole genome shotgun sequence.
ACCESSION   DACGEU010000062 DACGEU010000000
VERSION     DACGEU010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16211)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16211)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16211
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.062"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            <1..468
                     /gene="scm"
                     /locus_tag="IXR40_001910"
     CDS             <1..468
                     /gene="scm"
                     /locus_tag="IXR40_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HAQ4361748.1"
                     /translation="TSASSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSSDSSTTTS
                     DSTDTSASSDSTDTSSTTSDSSDSSTSSDSTDTSSTTSDTRHASVSFSKTSSDNRTNF
                     NLTNKTSNDNGNKSKRALPKTGSQSNNWITLAGVILLVIGLRITFMSYKKSKR"
     gene            complement(623..1609)
                     /locus_tag="IXR40_001911"
     CDS             complement(623..1609)
                     /locus_tag="IXR40_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HAQ4361749.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(1632..2198)
                     /locus_tag="IXR40_001912"
     CDS             complement(1632..2198)
                     /locus_tag="IXR40_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HAQ4361750.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKQDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            complement(2212..2628)
                     /locus_tag="IXR40_001913"
     CDS             complement(2212..2628)
                     /locus_tag="IXR40_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HAQ4361751.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            complement(3085..5019)
                     /locus_tag="IXR40_001914"
     CDS             complement(3085..5019)
                     /locus_tag="IXR40_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAQ4361752.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            5321..6256
                     /locus_tag="IXR40_001915"
     CDS             5321..6256
                     /locus_tag="IXR40_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HAQ4361753.1"
                     /translation="MKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSESSTAQSST
                     AKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKYDNVNENG
                     ESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSSESFQNYA
                     QQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGKVTESNFD
                     YIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPANVEVVTGA
                     THSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            6346..7449
                     /locus_tag="IXR40_001916"
     CDS             6346..7449
                     /locus_tag="IXR40_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HAQ4361754.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            7462..8415
                     /gene="menA"
                     /locus_tag="IXR40_001917"
     CDS             7462..8415
                     /gene="menA"
                     /locus_tag="IXR40_001917"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HAQ4361755.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFALVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(9229..10575)
                     /gene="gor"
                     /locus_tag="IXR40_001918"
     CDS             complement(9229..10575)
                     /gene="gor"
                     /locus_tag="IXR40_001918"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HAQ4361756.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(10709..11950)
                     /locus_tag="IXR40_001919"
     CDS             complement(10709..11950)
                     /locus_tag="IXR40_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HAQ4361757.1"
                     /translation="MTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAYGLRS
                     RAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISAVIVS
                     DPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVAEIRK
                     NTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFGQERN
                     SLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNVYKAA
                     VDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVYKFVG
                     EVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRAPNPM
                     MILTMPVAQPVKPGDMIRKRK"
     gene            complement(11968..12891)
                     /locus_tag="IXR40_001920"
     CDS             complement(11968..12891)
                     /locus_tag="IXR40_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HAQ4361758.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(13112..15604)
                     /locus_tag="IXR40_001921"
     CDS             complement(13112..15604)
                     /locus_tag="IXR40_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HAQ4361759.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(15611..16078)
                     /locus_tag="IXR40_001922"
     CDS             complement(15611..16078)
                     /locus_tag="IXR40_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HAQ4361760.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
BASE COUNT         4763 a         3390 c         2881 g         5177 t
ORIGIN      
        1 acatcagctt caagtgacag tacagatact acctctacca caagtgatag cacggacacg
       61 tcagcttcaa gtgacagtac agatactacc tctaccacaa gtgatagctc agattcatct
      121 accactacaa gtgatagcac ggacacgtca gcttcaagtg acagtacaga tacatcctct
      181 accacaagtg atagctcaga ttcatcaact tcaagcgata gtacagacac gtcgtctacc
      241 acaagcgata cacgtcatgc aagtgtctcc ttctcaaaaa caagttcgga taacaggacg
      301 aactttaact taactaataa aacaagcaat gacaatggaa acaaatcaaa aagagcactt
      361 cctaaaactg gaagtcaatc gaataattgg ataacactcg caggcgttat attacttgta
      421 atcggtttaa gaatcacttt tatgagttat aagaaatcga aaaggtaaaa aaatattcaa
      481 gataaaaaag agcaacgtcg ctaacggacg ttgctcttta tttttgcttt ttatcataaa
      541 tacaagaact acaattcaat ttgtcaaaaa acacgtagat ttccttctga gaaatttatt
      601 tacgtatcga acctttccct attcagtctt tgcgatccaa aatcagttgg gtaagggaaa
      661 agagattctc ttttgttcga agagaggtgg caggtaattt ctttatttcc ttcaaagcct
      721 tttctgtgta agaggccgct aacttcctag cttcttccac gcctcctgta tgttcaacga
      781 ttttgcgtac ggcgtcgaca tcttcttctg tcattgccgc tttcttctct aaataaggta
      841 gtagctttgg tttgtttttt tgcaaagagt agatcaacgg taaagaatag accccttgac
      901 gcatgtcttc tagtacaggt ttgccgattt cctggctctc ttttgtataa tctaaaatat
      961 catcgataat ctgaaaggcc atcccgatag aaagtccgat atctcctgct ttttttgcga
     1021 agcgctcgct tgttccactt tcaaaagcgc caacagaaca acttaattgg aacagttcag
     1081 ctgtcttacc tgaaatattt tccaaatatt cttttacaga aagttcataa ttatagcgat
     1141 catccatctg ccctaattcg ccattcaata ctttttccat actgcgagaa ttcaattgga
     1201 gacttttcaa ggaagtggag taatcagaca atagtttaaa acagcagaca aataaatagt
     1261 ctcctgcata gacagaaacg acattaccaa actgactacg gatattaggc tgaccacgtc
     1321 gcagatccgc ttcatcaacg atatcatcat ggatcagtgt ggccgtatgg agcatttcga
     1381 tagaagctgc caaagcgatg gctttgtctc gatcttgctc tggtccaaat tgtgagaaca
     1441 atagctgata ggcaggacgc aacagctttc cgccggcatg gatcgtttct ttgattgctt
     1501 gttcgacagg tttgtttttc aggcggacag tttcttccat ccgttttagt gtttctgtca
     1561 attctttact taaagcagga tagttttccc acattggatg tagcttcata aaaaaactcc
     1621 ttgtgtgacg attatttttt ggtaaacatt gggctccatt tttgtttggt tccctgctca
     1681 taatcttttt ggaatcgttg aagtgtctgc acatgtcgta aaagataatt cgctgcgatc
     1741 ccgattgcaa tccctgataa aatccctaaa actgaaagga ctggcaagta caacatgact
     1801 gtccatgatt gtgcaatgaa agaagccatc aaaagctgtc cgacattatg catgaaaccg
     1861 ccggccgcac taattccgat gatactgaca cgttttggtc ctaattgctt gaccaataac
     1921 attccaaaat aactaagcaa agcaccactc atactataaa ggaatgtgga aatcgttccg
     1981 cctagcaaag tagtcaggaa tagtcgtagc caaagtagta agaagctgtc ttgttttttc
     2041 atggtaaaaa tggcaacgat cgtgattaga ttggctaagc ctagttttgc accaggcgca
     2101 aaagaaaaag gataagggat catattttcc aataaaccaa tgatcactcc ttgtgcaaca
     2161 agtagcgaaa tataaatcat tttttgtaat ttactcatgg tgtgtaaagg tctaataaat
     2221 cagactgtct tcgtcacctc catctgttga acggacttcg atcactaatt tatgtggcaa
     2281 acagacgatg gtttcgccat ttttcgttgc ccagcctcga cgtacgcaga tctggtcatc
     2341 gcaatctgct tcttttatcc gtactcgatc gccatctatc tcgatcaagt tataatctcc
     2401 gtgttcatct ttgtaagtat atgtgttgct ctcttctcca gccatcaaag ggaatgtttt
     2461 gatttctgtg ccatccacac gcagtaccgc ttctttttct gctgttgcgg tgttttgctg
     2521 aagaccaaaa atcatgactg gtaaaaaaga aagaacagtc aaaagcaaaa taataaaaac
     2581 atcccaaggt ttgagcagac ttttttcagc aaattcttta aggctcattt ttgttctcct
     2641 ttttccagat taactcaccc aattttagca taaaaacaag aggttgtgac acctgtgtct
     2701 tgctttgagt aataagaacg aagaatagaa aacagctttc catgttttct aattctttgg
     2761 gcttattacc gagaagcagc aggtggaaca ccgtttataa caagaggttg tgacagaagt
     2821 gggcaacttc aagaaataag aaggaattta cgaaaattac ttttcaagtt tttgtgaaat
     2881 ttcggcttat ttttcgaaga agctacttct ggaacaccgt ttataacaag aggttgtaac
     2941 agaggttgtg acacctgtgt cttgctcatg gaggcttatc tcgggcatct tattccttta
     3001 attttacata aaaaggaggc tgtgacggtt tgtctcagcc cctttctatt gaaatcttgc
     3061 attcaaataa cgttctttat ctatttattt cttgccgtac tgggaacttg gtctaccgta
     3121 ccaccaatta cctagtgtac gttgtagcca tggaattacc cagcgatcca acccaatcgc
     3181 acgtccggaa ccgttcatca atgcgaaagc aacaaaaatg aaccaaatgt ttacccagta
     3241 aaacatgcct gataagcaga acgtgatcac caatacaatc gttgtcgcac tgcatagcca
     3301 tgtgaataat ccagcaatca atgctaatgc caaggcaatt tcaaagaata ccatgaattt
     3361 ttggaagaac attgctacat cattgtttgg catgatcact tgcatgatct ttgtgaacca
     3421 gtctggtgac ttctcaatca cagccattgg ttcttcaccg tatgcataac tcaaaccaaa
     3481 atgtgcagct tgagtcgctg cttctccggc acttgcccct gctccgctgg cagctgtggt
     3541 tgcatcacca gcagcagaag caccactggc aacatctgtt acattgtatt cccatgtcca
     3601 agggaacaca ctgtttccag tgaaccatga tccttcacca aaccaagtac ttggtttgaa
     3661 cacttcacca ttcccaatga tttttttgga agcttcaacg aaccaaacta aaccatagaa
     3721 aatacgaagt ggcacactcc ataagacatt gccgtaacga gaagaatgtc ctcgagtcac
     3781 gttgcgatca tctttgatat ggaaaaactc atgcattaaa tattggaaca tataataacc
     3841 agaacgaata tcaaagaagt atttcaaatt cacgatatgt ttcattacga tagctaaaaa
     3901 tccgcttaaa tggatcttat caaataggtt agctaccccc catttggcac caatagaaac
     3961 cataaatcct tgatagtttc ctttaaattt atgcttttct ccgcctttga tcgaagccac
     4021 gatattcgct gcggctgtgt gtcctgtttg ttcagcagct tgaacgatct gcggtgtcgg
     4081 tgttcctggg aattcttcat aaaagactaa atcaccaatg atatagatgt ttttatcttc
     4141 gtagcctttt gcctgcatat attcattggc gatcaaccgc tgtccgcgtg ctgattctaa
     4201 tccaaagtca gcagcgtcag aagttccttt gacaccagct gtccaaatca gtgtgtgagt
     4261 cggaatgttg cgtccgtctt tcaatttgat atgatcagca gccacttcta cgattggtgc
     4321 attcaataat aattccacgt tgtgcttacg caaatagcgt tcagcttttg cagcatcatt
     4381 tcgatccaac atattcaaga tcgtcggcat tgcctctacg accatcagtg tgatttcgtt
     4441 tggatctaat ttataatctt tggctaggcg atttttccag tcgatcagtt ccccaatcat
     4501 ttcaataccg gtaaatccag aaccacagac aacgaaagtc agcatggctt tacgcagttc
     4561 atcatctggt tccaatgcag cttttgctac tgtcttctca atatgttccc gaatccttac
     4621 agaatcttca aatgaccaaa gggtgaatcc gtgtgctttg acaccaggtg taccaaagtc
     4681 attcggctct ccgcccattc caaggatcag ctgatcaaaa ggataggaac ctaatttggt
     4741 cttgacgatt tttcgttctt tatcgatacc gattacagtg tctgtgacaa gttgtacatt
     4801 cttttgacga gcaaacaaat gctgcagatc gtattggatt gcttctggtt ctacacgtcc
     4861 gccagctact tcatgcaact cggtcatcat agtatggtac gaatgacgat cgatcagagt
     4921 aattgctaca tcttcttttt tcagtttctt tgccaagtat tttgtagctg aaacaccggc
     4981 atatcctgct cctacaacga caatattttg ctttgccatt gatcatccgc tccttataga
     5041 ctatctatat aatgaatata tgataattct tttagtttga tacttattac acaatctcca
     5101 tatattatat agatgttctg ttcttttgtc taactccttt tggatttttt tcaaatttta
     5161 aaataaagcg ttttttcacg aaatttgctg aaagaaaacg tttgaaatat tacatgggtt
     5221 atttatcaaa aatagttgac ttataggcta aaaagattag aatgtataat gaatcacaaa
     5281 gaaaaattgt ggactagaaa tggaatggtg gggtattaaa atgaagaaaa aacgttttgt
     5341 aactggattt gccgtattag cattttcagc tctagtgtta ggcgcttgcg gcgcagatga
     5401 caacggaagc tcaaactctt cttctgaatc atctacagca caatcttcga ctgcaaaaag
     5461 cacaacagaa tcatctgcaa aagttgtagc tggcggagat ttgcaagacg gcacatataa
     5521 attagaagaa aaaaattatt caaatggtta ccgtgcagtc tttgaaatgg ttgtaaaaga
     5581 cggcaaaatc actgaatcaa aatatgataa cgtcaatgaa aacggcgaat caaaaacaaa
     5641 agatgcagaa tacaacaaaa acatggaagc aaaatctggc acaaacccag aaaaatacat
     5701 tcctgagttg aatgaccaat tcttaaaagc acaaagcgca agcggtgtgg aagtcgtaac
     5761 tggagctact cactcatctg aaagcttcca aaactacgca caacaattga tccaagctgc
     5821 tcaagctggt aacacagata caatcgaaat cgacaatggt gctgatttga aagacggcac
     5881 ttacaagctt gaagaaaaga actactctaa cggctaccgt gtgcaattcg aaatgacagt
     5941 tgctggcggc aaagtaactg aatcaaactt tgattatatc gacaaagacg gtaaatcaaa
     6001 acaagatgat acagaatata atgaaaatat gaaagcaaaa agcggtacag aaccaaaaac
     6061 ttacatccct actctgaacg acgaattcgt caaagcaatg ggcgaagaag atggctcacc
     6121 tgctaatgta gaagttgtta caggtgctac acacagctca cattcattca tcatgtacgc
     6181 acaacaatta gtgaatgcag ctgaaaaagg cgacactcaa acaatcgaag tagataatat
     6241 cgtaacagaa aaataatcac ataatcatac taataaaagt tggagggtgg gacgatagcc
     6301 agattaggca gtcgtctcac ctttcaaaat gaagagagga aaaagatgcg gaaaaaacta
     6361 ctattttcct taatcacact gggcatctct tttatggtgc taactggctg cagcaactca
     6421 gcaaataaaa caaccactga aagttcagca gctaccaaga tattgaaaga tccatattct
     6481 gatgaacagt tcttgttagg gacttacgtt cgtatccgtg tgtatgatga aggcaaagaa
     6541 tcagcattga aacctgcctt cgatcgagta aaagaacttg gtgataaaat cacgatcaat
     6601 caaaaaggtt ctgagatcga tgaagtgaat gagcaagctg ggatcaaacc agtaaaagtt
     6661 tctgatgacg tctacacgtt agtcaagcgg gcctacgaat atagccaaga ttctcaaggc
     6721 ggattcgata tggcgattgg tgcaatcaca caattatggc gaatcggttt tgatgacgcc
     6781 agaaaacctt cccaagaaga aatcgatcag gcattgaaat tagtggatta tcataagatc
     6841 gaactaaatg acaaagaaaa aactgtttat ctaaaagaaa aaggaatgat catcgattta
     6901 ggtgcaatcg ccaaaggtta cattacggac gaagtagtga aagtcttgaa aaaacaagga
     6961 gtgaccactg ccatcgttga cttgggcggt aatgtctatg tcttaggcca cagcccaaga
     7021 ggcgaaaacc aagactggac agtcggcatc caagatccga acatggctcg cggatctgtt
     7081 ttaggttcta ttaaagaacg gaacaaaaca ttagttacct ctggaattta cgagcgttat
     7141 ttagaagtag atggcaaaaa ataccatcat ttgtttgatc caaaaacggg ttatccgttc
     7201 gacaatgata tcgcaagtgt cacgatcata acagataaat caattgatgg tgacgggttg
     7261 tctacagcag tcttttcaat gggtgtgaaa aaaggactgg aatacgtcga aagcgaattg
     7321 aataacggga cggaagcgat cttcgtgaca aaagacgata aagtatatgt gaccgatcca
     7381 atcaaagaca ccttcaaatt atcggaggac tcccattaca cgatgggtga ccgttctgaa
     7441 ctaaaataag gagtacgaac catgacacta aaaatctttt tagaagtagt tgaaatacga
     7501 acaaaggtgg ctagtgtatt tccttttgcg gtaggggtat tattctctat cgcttttttt
     7561 catgagatac attggctaaa cactttttta ttttttattg gaatgctagt ttttgattta
     7621 gcgactaccg ctatcaataa ttacatggat tatgaaaagg ctcattctga agtatataag
     7681 tatgaagaaa atgtcattgg ccgcagaaat ctatctcctg tattgattcg aaacatgatt
     7741 ttagctatga ttgcatttgt ttttgttatc ggcgttattc taacgatcaa tacgggttgg
     7801 cttttacttt tgatgggatt tatctgttgt tttattggag tattctatac attcggaccg
     7861 attcctttat ctcgaatgcc tttaggggaa attttcagtg gggtgactat gggccttgga
     7921 atttttgcca tggtcgttta tgtcaataca ttcggttcag atgtctatga tctgacagtc
     7981 aacttttcat ctggacaatt tgctttggta ggaaatcttt gggctatagc agcaatcgta
     8041 ttagcttcct tacccttggt gtttacgatt gccaatatca tgttggctaa taatttgcgg
     8101 gatcttgacc gtgatattga aaatcatcgc tatacactag ttttttatat cggacgtcct
     8161 gcgggaacag tcttattcca gctattgatg tatgcttgct atttcgtgat tttaatgggg
     8221 ttgttgagcg gtatctatga atggccgatc ttggtcacct tcttgacctt gccaattgtg
     8281 aagaagcatt tggatcaatt caagcaaacg ttaccccagc ctatcagttt cagctattcc
     8341 atcaaaaata tggtcttatt caatgccagt tatgtattgg ggctattact aacaatcatt
     8401 atgcaagcca tttaacagca tgaagaggtt gtgaaaaaac tgccctgcat caagtaataa
     8461 gaacagccaa ataaaaatag ctccttatat ttttcgtttg gttgggctta ttaccgcaga
     8521 tgcaagcttt tgaacaccgt ttatcaggag gttgtgaaaa agtcgcttag tttcgagtat
     8581 taagaaaaat tttgtgaaaa tggctttcca catttttgca taaatttggc ttaataccga
     8641 gaaactggct tttgaacacc gtttatcaga ggttgtaaaa tcagtgtttt gtcctgagta
     8701 ttagagaaac aaatggaaaa atagttcctc atattttgcc gttttttgag ctaataccga
     8761 aggacagctg attgaacact atttgttcgg aaaaagtgac taactatgac acaatttttt
     8821 tcacagtccc ttttttcact tgatttgatt cgtaccagcg aacttgacga gaactttctt
     8881 ggtttggtaa ctatatggta ttcttttaac atcctcgttt gcttcttcta atttatttat
     8941 acaaagtcac acttttttaa acatctgttc ttcgatacat ttctatttct tttaaacatc
     9001 gataccaata ttttgaactt aagagtgcat accaaatgga ttcatttact cttcgtcagt
     9061 tacgaagata atcaaaatct ccaacttccc tacttatttc gttttgagaa ttatcgaagc
     9121 aatcttacat aaataactaa aaaacaaaaa accagaaaat cagtatactg attttctggt
     9181 tttacatggt ttgttcaata aaaagctgtt ggaactgtta atattaaatt atcgcatcgt
     9241 tacgaattct tccgctcctg ttggatggat ggctactgta ttgtcaaagt cttctttagt
     9301 tgcacccatc ttgatagcca cggcaaaacc ttgcagcatc tcatcgacac caacaccaat
     9361 agcatgtaag ccgacgattc tttcttcttt tccgacacag atcaatttca tttcgcattt
     9421 ttggcgataa tcatttaatg caaagtacat tggggtaaag cgtgaacgat aaactttcaa
     9481 ttcattttcg ccatattttt ccaatgcttc ttcttctgtc aaaccaattg ttgcaattgg
     9541 tggatgcgta aagacgactg tcggaacaag tttatagtca agataagaat ctttctttcc
     9601 attaaataaa cgttctgata aacgtctacc agctgcgatt gcaacaggag tcagatctaa
     9661 tttaccgatc acatcaccaa cagcaaaaat atgttcatcc gttgtatttt ggtatttatc
     9721 tactttgata aacccttttt tgtccaattc cacatttgta ttttccagac ctaatttttc
     9781 ggtattcggt acacgtccac cggcaaaaag tacacaatca ccagttaagg tttcaccatt
     9841 ttcaaatagc accgtatatt cgtcattgtt tttagtaatt tctttagcaa tatgatgtgc
     9901 gtaagttttt attccagctt cttggtacat ttggatcaaa ttgtccgaaa gcattttatc
     9961 aaacgttcta agtggtcgtt cttttcgata tgcccacatg acttcactac ctaaaccacg
    10021 aaatacacct gaaagttcag ccgcaatgta tccagcacct aaaacgattg ctctcttagg
    10081 taactctgtt aattcaaaaa atccatttga atcaattgcg tattctccac caggaatggt
    10141 cattttactt gcacggcctc cagtagcgat caagatttta ggagcacgat aggtttcacc
    10201 gtttacttcg atcgtttgac tatcgataaa agtagcgtaa ccttttatag cctcgacatg
    10261 attgctatct aatcctcttt gataagcacc gtgtagaaaa tcaatatatt tttctcgtct
    10321 ttctactaga ccggcgaaat caacattttt taaatctgct tggataccgt aacttgaggc
    10381 atctcgttca attgtttcca aaatcgtact tgcttgccac ataacttttt taggtacaca
    10441 accgacgttg acacatgttc cgcccaattc attcgcttca atcagcaaaa cttttgcgcc
    10501 atgcatccct gctctgtttg ctgaagcaat accgccagag ccgccaccaa ttacgatgta
    10561 atcatatatt tgcattttgt tcctccttat tgaagagatc aatcaaaacc tttatttaac
    10621 gatccttttt ctacagaaaa caagtgtaac acttttcttg aattttgtat gcgaagatgc
    10681 ttaaaacagg gatatatcag ctttttcctt atttacgttt tcggatcata tctccaggtt
    10741 tcaccggctg tgcgactggc atagttaaaa tcatcattgg atttggtgct cggtcaatgg
    10801 attcgccttc ttcattatgc ataacttcaa cggtttgact gaaatgactg aatcctggac
    10861 cataaaattc gatttcatct cctacagaaa acaagtttct ctgacgtatc gtagcaatct
    10921 gtgttgcctc atcataagat aatacttcac cgacaaattt atatactggg attttacgac
    10981 gttcaccgaa taattgttcg ttttcagttg gtgtattgta gtaaaaacct gtagctaatt
    11041 ctcgttgtgc tactttccat aactcgtcga tccattcttg cttgcagaca tagttttcag
    11101 gatcttccat ataactgtct acagccgctt tatagacatt tgacaccgta gatacataat
    11161 ggatcgattt cattcttcct tcgatcttga agctgtctac gccgttttca atcaattctg
    11221 gaatatgttc gatcattgac atatccactg cactcatcga gaattcttct tccacttcgc
    11281 ctgtatcagt taaactgttt cgttcttgac caaaaggcat atcgaacaat ccatacttcc
    11341 agcgacaaga ttgagaacat ccgccacggt ttgcatcccg catcgacata tggttggaca
    11401 atgtgcatcg accagaataa gagatacaca tggcaccatg gataaatgct tcgatttcgg
    11461 tatccgtatt tttacgaatc tctgccactt cctccattga aacttcacga gctaaaacga
    11521 cacgttccaa cccttcttct ttccagaatt ccaatgtctc aaaattagtt gctgaagctt
    11581 gagtggataa atggatcggc agacctgggg cttctgtcgc acaaatttcg atcaaagctg
    11641 gatcagaaac aatcactgca gaaataccga catcacgcaa actgcggaaa aattcccctg
    11701 ctccatcttc atttccttca tgggtgacca tattagcagc aacgtatacc ttcgcatcat
    11761 gttcttttgc aaaagcaact ccttcagcca tttcttcata agtaaaatta cctgcacggc
    11821 ttcttaaacc atatgcattc ccgccaatat atactgcatc tgctccataa tggatcgcgg
    11881 tttttaactt ttccagtgtt cctgctggcg ctaggatttc tggtcgtttc aattttcttt
    11941 ttactgtcat ttctttcatc atactcctta tttgatagca gaaggatcaa tataaaagaa
    12001 tcctgtatct aattcacggt tttcaggatg caatttactg atttcgctag tcattttttc
    12061 cgctttttct tgatcccagc taccttctaa aatttgtttt tttgcttcgg cgaatagtcg
    12121 agtgatgttt acgaattttt cgcctggagt aaataatccg tccaatttcc atgtacagta
    12181 atgatgctga taaagttcat tcaattcatt cgagagattc agatcattgc tggcaaaaat
    12241 atgtgtgcca tgactatctt cataaataga ataatgtgtc tcttcttttt taggttccga
    12301 gataaaaaga cctctttcac gatctttttg ttcgtcttgt ttcgtatagt tatagtaatt
    12361 ctgtagcagt ggacgtttgg attgatggat gcatgtagca ccatacacaa gggtttctac
    12421 aggaatatcg agtttttctt ccatcgcctt catctcttca aaaggaactt cacgagcaag
    12481 tactgctcca actgcgcctt ttttcgccca gaaattgatt tgacgtgcgc tcgttactaa
    12541 tgtttcagca tcataaatat acggtatacg caattcagga ttttttttca tcgtataaat
    12601 aatacctgta tcaccaactg tgatcacatc tacgtttatt tcttttaaaa aagccaaata
    12661 ttcaggtaca tttttcattt tttcaggatg aatgatccca tttacagcaa tattcgcttt
    12721 tttaccatac ttgtgtgcta attctaccaa ttgtcgctgt tcttctcgtg taaatgaagc
    12781 aggcagacgc aatccaaatt gctcttcacc gaaatatagt gtatctgcac ctgcagcaag
    12841 caactgttct gcttgttcaa tagtttctac tgtggttatg agttcgatca taattttctc
    12901 ctcctacaac ttcataatag tagcatagct ctaaaaactt tccaatactt cttctattta
    12961 aagtcggatt tttgaaaatt atttcacaaa aaatcaaaat aaagttcgat atattctgtc
    13021 caaatataaa aagagattgt gacaaaaatc ttgtcacaac ctcttaatca agtcttacta
    13081 ttataaaaat tcagctacac aggccaagta actataggga acctactgtt tcctttttag
    13141 gtccgcgaac attcaatgtg atcttacctt ttgaagcacc tactgttacg tggtcaccta
    13201 aacgaatttc tccgccaagc aaagcctcgc tcaatcgatc ttcaatttct ttttgaagtg
    13261 cgcgacggat tggacgtgca ccatattcag gatcaaatcc agctttcccg atcacatcga
    13321 ttgcagatgg tgtgattttc acttgaatat cttgttcttt caatcgtttg ataatcgctt
    13381 tgctcatgat ttggacgatt gtatggattt catctttact caatgaatgg aagacgacag
    13441 tctcatcgat tcgattcaag aattcaggtc ggaaagcttt ctttaactct tctaagatac
    13501 gtttttgcat ggctttgtga tctttagtaa catcttggac attgaatccg acattttttt
    13561 cttctcgaat ttgtgtcgct ccgatatttg aagtcataat catgattgta tttctaaagt
    13621 ccacttttct acctttagaa tctgttaaat gaccatcatc caatacttgc agaagtaaat
    13681 tgaaaacgtc tggatgtgct ttctccactt catctaagag aatcactgaa tatggttttt
    13741 gacgaatttt ttctgtcaac tgtccacctt catcataccc tacgtatcct ggaggagacc
    13801 cgattaatcg gcttgtactg tatttttcca taaattctga catatcaaca cggatcaggg
    13861 catcttcact tccaaacatg acttctgaaa gtgctttggc caattctgtt tttccgacac
    13921 cagttggtcc aaggaacatg aatgaaccaa ttggacgatc aggatctttc aatccgcttc
    13981 gtgcacggcg gatcgcacgt gaaactgctt tgacagcctc atcttgacca acgacacgtt
    14041 catgcagaag tccttccagt tctaacaagc gttcgctttc ttttttctcc aactgctgta
    14101 gagggacacc agtccactcc gatacaactg tagcaacatc ttcttctgtt acacgatcag
    14161 aataaccttg ctcctgtttt gcttcaattg cagaaacttt ttgcagcttt ttacgtagtg
    14221 ctttttcttg tctgcgtaat tgagcagcat tttcaaagtc ttgtttttgg atcgctgctt
    14281 ccttttcttg tactagttca tcgatttcta gtttgatcac agttgatttt gttaagtgat
    14341 cggtttgatc caaacggact ttcgctgctg attcatcgat caaatcaatt gctttatcgg
    14401 gtagttgacg agaagtgata taacgaacag aaagattgac tgctgctcgt acagcttcat
    14461 ctgtgatctc cactccatgg tgctcttcat atcttgtacg taatccttga agaatcactt
    14521 ctgcttcttc aggagttggc tcatctactt gaatgcgagc aaaacgtcgc tctaatgcag
    14581 aatctttttc gatatatttt tgatattcat ctagggtcgt tgctccgatc gtttgtaatt
    14641 ctcctcgagc taacgccggt ttcaagatat tcgaagcatc aattgctcct tctgctccac
    14701 ctgcaccaat taaggtatgc aattcatcaa tgaataagat tacttgacca tcattataga
    14761 tttcgtcgat gacctttttc attcgatctt caaattcacc gcgatatttc gtaccagcaa
    14821 ccaaagatcc catatcaagc atcatcaggc gcttttcttg catgtcttct ggcacttcac
    14881 ctaaaatgat tttttgagct aacccttcag caatggctgt tttgcctaca ccaggttcac
    14941 ccaccagtac agggttattc tttgtccgtc ggctaagaat ctggataagc cgtttcactt
    15001 ctctcgaacg accaacaact gggtccagct tgttttcttt tgctaatttc gtcaaatcac
    15061 gtgctaatga atctagcgta ggtgttcctt gcggtgtttg ccgtttatct tgtacattta
    15121 catttctacg acgattcatt ccttttccag cagaatcacc agctagcccc attttttgtt
    15181 tcagaacttg acgggctttt gaaaggctga tacctaagtt gatcatgatt cgagtagcca
    15241 tgatactttc atcttttaat aagctcatca aaatatgttc tgttccaact ttttgagaac
    15301 cagttttctt cacttcgctg ctagctaaag caaaaacttg tttcattctt ggtgaatatg
    15361 gaagaaagac tcctttaggg taagaacgga taccaccata accaatcaga tgttcaattt
    15421 cttcataaat ttccgtttca ttcaaatcca tttcacgtaa tacttttcca gcaattccat
    15481 tttgctcgac cactaaggct agtaaaacat gttctgaact aactgattga tgtttcaacc
    15541 gttttgcttc ttcttgtgca atttctaata ctgcttgggc tctttcagta aaaagttctt
    15601 ccatctaatc tcacttccca tcttcataac ttaaacgttc cagaaatgct cggagaatcc
    15661 gagcacgtgt atgatcttca tattcattga aattcaatgt gttttttgca attgcactca
    15721 acatcaagtt tccttctttt tttgtaatta tttggtcttc ataaagtttt tgaataatag
    15781 caaaagcatt tttctcactg attgtatcat caaataactg atttatctgc tcaagtaatt
    15841 gttttttatc tgaaatcctt acttttgcaa ttcgtatata accaccacca ccacgtttgc
    15901 tttctactag ataaccacgt tggatggtaa aacgggtatt aatcacatag ttgatttgtg
    15961 aaggaacaca gttaaagagg tctgccattt caatccttcg aatctcgatc atttcactat
    16021 tttccagaat tttctttata tatgattcaa ttaaatccga ggtattctga tgtgccatct
    16081 tattcattcc ctttgactaa tattgacctt aattataacg aatttgataa tagaaagaaa
    16141 gaagaacgct ttttgttaaa taaatccttt agaatcaaca aaaaaaaata cggaatatac
    16201 tattccgtat c
//
LOCUS       DACGEU010000063        15860 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.063, whole genome shotgun sequence.
ACCESSION   DACGEU010000063 DACGEU010000000
VERSION     DACGEU010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15860)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15860)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15860
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.063"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(12..482)
                     /locus_tag="IXR40_001923"
     CDS             complement(12..482)
                     /locus_tag="IXR40_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HAQ4361761.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
     gene            complement(641..1099)
                     /locus_tag="IXR40_001924"
     CDS             complement(641..1099)
                     /locus_tag="IXR40_001924"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HAQ4361762.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            complement(1270..2415)
                     /locus_tag="IXR40_001925"
     CDS             complement(1270..2415)
                     /locus_tag="IXR40_001925"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HAQ4361763.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPDHELHGVAKQQMSGFSGMISFTLKNEESAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            complement(2428..3345)
                     /locus_tag="IXR40_001926"
     CDS             complement(2428..3345)
                     /locus_tag="IXR40_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HAQ4361764.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIYL"
     gene            3773..4336
                     /gene="efp"
                     /locus_tag="IXR40_001927"
     CDS             3773..4336
                     /gene="efp"
                     /locus_tag="IXR40_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HAQ4361765.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
     gene            4822..6081
                     /gene="lysA"
                     /locus_tag="IXR40_001928"
     CDS             4822..6081
                     /gene="lysA"
                     /locus_tag="IXR40_001928"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HAQ4361766.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            6068..6868
                     /gene="dapF"
                     /locus_tag="IXR40_001929"
     CDS             6068..6868
                     /gene="dapF"
                     /locus_tag="IXR40_001929"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HAQ4361767.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            6871..7752
                     /locus_tag="IXR40_001930"
     CDS             6871..7752
                     /locus_tag="IXR40_001930"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HAQ4361768.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            7749..8465
                     /locus_tag="IXR40_001931"
     CDS             7749..8465
                     /locus_tag="IXR40_001931"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HAQ4361769.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            8471..9166
                     /gene="dapD"
                     /locus_tag="IXR40_001932"
     CDS             8471..9166
                     /gene="dapD"
                     /locus_tag="IXR40_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HAQ4361770.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            9182..10183
                     /locus_tag="IXR40_001933"
     CDS             9182..10183
                     /locus_tag="IXR40_001933"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HAQ4361771.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            10180..11541
                     /locus_tag="IXR40_001934"
     CDS             10180..11541
                     /locus_tag="IXR40_001934"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HAQ4361772.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            11501..12652
                     /locus_tag="IXR40_001935"
     CDS             11501..12652
                     /locus_tag="IXR40_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HAQ4361773.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            12627..13796
                     /locus_tag="IXR40_001936"
     CDS             12627..13796
                     /locus_tag="IXR40_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAQ4361774.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            13971..15350
                     /locus_tag="IXR40_001937"
     CDS             13971..15350
                     /locus_tag="IXR40_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAQ4361775.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            15631..15860
                     /locus_tag="IXR40_001938"
                     /pseudo
     CDS             15631..15860
                     /locus_tag="IXR40_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         5185 a         2799 c         3378 g         4498 t
ORIGIN      
        1 tttttattaa gttaaagaac ggattcaatt gcagcggtca ttttcaatgg agaagtttgt
       61 ggtgcaaatc gttcgattac tttgccattt ctatcaatca aaaatttagt aaaattccat
      121 tttattgctt tagtgacagt accaggagct tcatttttaa gataagtaaa aagaggatct
      181 gtattttctc catttacgtc aatcaattga tgcataggga aggtaacgcc ataagtggtt
      241 ttacaagctt ctgctgcttc agtcgctgaa tctagctctt gtttaaattg attggaagga
      301 aagcctaaga taaccagacc ttgtgtctga taagcttggt aaagttcttc taattgttta
      361 aattgaggtg ctagaccgca ttttgttgca gtgttaacaa tgattatcgg tttgcctgca
      421 tattttttca atgaatagac agtgccgtct tctaaagtag tttcaaaatt ataaatagac
      481 ataaagtttt ctcctttcta ttttatataa taaaaagagc gctaaactga aaactagcta
      541 tttgttttcc cgtttagaac tcttttcaga caataaatat ttaataaaat acgaagataa
      601 gatagctata ttgcttctca tctttacgtt cttttagaaa ctatgcttct acttcagacc
      661 attcatcgcg ttttgctaaa aattcacgag ccaaagcttg tgcaccttct agtgtatggc
      721 tggcagccca gccacattgt gtttcattgc ttgcaggtac ttcagtagct tcaagaacat
      781 ctttcattgt tgcttcaaga acatctaaaa tgtcttcgta gctttcatga ttcaatacag
      841 tcaagtaaaa gcctgtttgg catcccattg gagaccagtc tacgatgtaa tctgcgtgat
      901 tgcggattag ttcggcagtc aagtgctcaa gtgaatgtag acttggcatg tccatgtgtt
      961 ctttatttgg ttgtttaaag cggacgtcgt atttaatgat gacatcgcca tgcgcacccg
     1021 tttttcgatc agctacacgt acataaggtg ctttgacttt tgtatggtca agattaaaac
     1081 tttcgacatt cattctcatt tgtaagactc ctatctgttt gttcattcgt tttgatgctt
     1141 ttcactaaag aattatttag tgaaatttac aaaaacgtct ttctacttga ttctaacact
     1201 tatcgtttcc aaggtgtagc aatctgaaat attttttaga tttttctgct aagtcgttta
     1261 ttgggacttc tagttcttga ttctgtcaaa tgcctgagct aaatcgttta tgagatcctg
     1321 accatactca attcctacag aaagacggat caagccgtcc tttatgccag cctcttctcg
     1381 tttttctttt ggaatagacg catgagtcat gacagaagga atttccacta aactttctac
     1441 gccacctaaa ctttctgcta aagtaaatag ttggagtgat tcaacaaatg gaatagcaga
     1501 ttcttcattt tttaaagtaa aagaaatcat tccgctaaag ccgctcatct gctgcttagc
     1561 aactccatgg agttcatgat cgggtaatcc tggatagtag accttttcta ctgctggatg
     1621 agaaaataga aaatcagcta ccacaaaagc atttttttga tgttcctcca tacgaacact
     1681 tagtgtcttg attccgcgct gaagtaacca gctatcttgg ggaccaagta cggctccgat
     1741 agcattttgg taaaatccga tctgatcggc tagatcttta tggttagaag tcactaaacc
     1801 agctactaca tcgctgtgtc cgcctagata tttggtaccg ctatggacaa cgatatcaga
     1861 accgagatct aaaggtcttt gaaaataagg agtagcaaat gtattgtcag caataactat
     1921 caatccatgt tgatgagcca gagtggcact tttttctaaa tcagtaatct ttagaagcgg
     1981 attgctaggt gtttcaagat aaagtgcttt tgtattgggt ttgatggatt gttctatttt
     2041 atcaagatta ctcgtatcta tgatcgtgta ctcgagacca tttttagtaa gaactttgtc
     2101 aaatagacgg aatgttcctc catagacatc atctcctaat aagatatgat cgccagcttg
     2161 aaaaagagaa aaaacggcat gaatcccaga aagaccagaa gaaaaagcga atcctcgaac
     2221 accgccttcc aaatcagcaa tcagttcttc caatgcaaaa cgagtaggat taccagatct
     2281 tgaatattca tattgtttag gctggccgac gccatcttgc cgataagtgg atgtttgata
     2341 aataggtaca ctgacagctc ctgttgtggg atcttcactg atgcctccgt ggatcaattt
     2401 tgtttgaatg tgcatgtttc tttcctccta taagtaaatg ttttttgata aatagcggtc
     2461 tgctgcgtct ggaaaaatcg taacgacacg atgaccaggt ggtaaacgac gaatttctct
     2521 taatgctgct gcaaaagccg caccactcga acttccaact aatagtcctt gttctcgtgc
     2581 taactgccta gtatagttaa acccttctac atcagagatt gtctcgatct gattgattga
     2641 aaggggagaa agaaacggcg gaatgaattc tacaccgata ccctcaattt cgtgaggggc
     2701 tggatcacca ccatttaaca cagagccctc tggttctaca ccgattattc gaatgtcggg
     2761 atatttttct ttcaaaaagg tagaagttcc agcaaaggtt ccaccactcc caattcctgc
     2821 tacaaaacta tggatatttt ctttgatttc atgaaagatt tctggcccta acgtatgata
     2881 gtaagcagca ggattatctt tattttcaaa ttgaagaggc agatagctgt ttgatatctc
     2941 ctctgcaagt tttttacttt tgctgatggc accgatgatt ccttgctcac taggagaatg
     3001 gatgatcttt gctcccaatg ctttcatcaa ttgttgtttt tctaagctaa acttctctgg
     3061 aacaacaaaa accgttctta atttgtatgt gagtgcggcc agagcgatcc caattcctgt
     3121 atttccggca gttggttcga tgatcgtcgt tttttcattg atttttcctt gggcaaatcc
     3181 ttctttgatc aaataactgc ccaatctatc tttgatactt cctccaggat ttaaatattc
     3241 tagttttgca taaatagcag aacctttagg catagaatag tgctgattgt caaagcgata
     3301 aagcggtgtg gaaccaatag cttctgtaat tgtcgagata atcatgtggg cctcctaaaa
     3361 aaagataata aaaaaaggag ctgactatta aatcagctcc ttgaaagaca tagagaaaaa
     3421 ttgagtagat aaaaagataa gttacctggt actcattcta tgaagggcaa ttaatagaca
     3481 tgacaaatag tatgctgctt ttatgcacca tacaacagca acgattcaat tgtttttggt
     3541 tgctgactgt catgtgtatc cctccaagta aaatttttat taacgatagc atgaaaaaaa
     3601 ataaaagtca aaggcttgaa agaaaaaaat atttcgatag catcgtttac ccgtgtttat
     3661 ttttctgaca aataggcatg agaccttaaa agatagagaa tactctagtt ttctggccgg
     3721 ttgtctgata caataaagtt gattatgata aagaaaagaa ggagcaaaaa taatgatctc
     3781 agcaagtgat ttaagagccg gtatgacttt cgtacaagac ggcaaactga ttaaagttct
     3841 ggatgcaagc caccataaac ctggtaaagg aaatacagtt atgcgtatga aactgaaaga
     3901 tgtccgttca ggtgcaacat acgacacaac gttcagacca gaagaaaaat ttgaaaaagc
     3961 acatatcgac acaaaacctg tacaatattt gtacacgatg gatgatacag ctttcttcat
     4021 ggatttggaa acatatgagc aatatgaaat tcctgtagaa acagtagaag aagaaatgaa
     4081 atatatccta gaaaacatgg aagtaaaaat ccaatttttc ggtagcgaag tcatcggcgt
     4141 tcaattacca acaactgtcg tattacgtgt tgtggaaaca caaccttcca tcaaaggtgc
     4201 aacagtcact ggttcaggta agccagcgac aatggaaact ggcttagtag tcaatgttcc
     4261 tgacttcatc gaaacagatg aattgttgga aatcaataca gcagaaggtt cttatgtaaa
     4321 acgtgcgtca aaataattcg ctaacggatt gataagaatt tgaaaacaga gcttgacctc
     4381 ttgaaaggca gatcatcgga tctgcctttc aagaggtttt ttgtggaatc agcaaattga
     4441 aaaataaaaa agtatttgat tttatttata ttttgaaaga tgaatggcaa aagctagaga
     4501 aagaaaaaac tgcacttatt tatgaagaaa ttgaaatgat tcataaaatt gaaaatatcc
     4561 gaactattcc gaactatatt gaagcgaaaa tattttttca tcactaaata gtgttgaatt
     4621 tatgttttta tgtataaata gcttctaata gttcgggtat tttgttttta taaccatttt
     4681 tattcttatt tttaaaaaaa tatttcgaaa tatactagac aattcagaaa attttgttta
     4741 atattattcc aataaaattc aaatctttat caaatgaaat tccaataaaa acggaaaaaa
     4801 agtgaaaaga ggaatgaaaa aatgacagaa ttgataattg gcggagtcac agcaagcaca
     4861 ttggcagaaa agtataagac acctctgtat gtgtatgatg aagaaaagat gagacaaacg
     4921 atgctgtcat tcaagcgagg ctttgtatcg aaacgttttg atacaaaagt gctttacgcc
     4981 tctaaagcat tccaaacgat tgagatgctg catttagttc gtgaatatgg attcgggcta
     5041 gatgttgtca gtggtgggga aatctatacc gctttgcaag ctgattttcc tagagatact
     5101 atctacttcc atggtaacaa caagacgcca gaggaactga tctatgcact tgaaaatgat
     5161 ttgttgcata ttgttgccga taatttgatg gaagttgaat tattagcaga attaagccaa
     5221 cgctatttaa aaaaaatctg tatcatgctt cggttgaatg tcggagtaga agcacatact
     5281 catgaatata tcgtcactgc gcatattgat tcaaaattcg gcatgagcta tgaaagtaaa
     5341 gagtgccaac aagcccttca gttgataaaa gaaagcagct atctagagtt agaaggattt
     5401 catgctcata tcgggtcaca aatttttgat gttactgctt ggttagctga aatcgacaaa
     5461 ttgacgaatt acttaaccga ttttgaccaa cctctttcct tgaatcttgg cggagggttt
     5521 gggattcgtt atacacaaaa tgatcagccg atcccagtcg aagaggcact aaaaaaactg
     5581 attgaatata cggaagaagc tttggaaaaa cgaaaactga ccattcgtca attactgatc
     5641 gaaccgggta gaagtattgt tggagaagct ggtacaacac tatacacgat tggtttcatc
     5701 aaaaagacac cacataaaaa atattacttt gtagatggcg ggatgacaga taatatccgt
     5761 ccagctctgt atcaggcaga atacgattgt gatttagcag caaaactgtc ggaagaaaaa
     5821 acagagaaag tgacgattgc aggaaaaatg tgtgaatcag gcgatgtggt aattaaagaa
     5881 gcttatttgc cgaaagcaga atcgggtgat cttttagctg tttattccac gggagcttat
     5941 ggatactcga tgagcagcaa ctacaatcga gcgacacgac cagcagttgt ttttgtcaat
     6001 aatggccaat caagactgat tgttcgcaga caagcatttt ctgatctact aaggggggaa
     6061 gtttcctatg atccttcata aatataatgg ctgcggaaat gattttatct tattagatta
     6121 cgcagaagac acagattata gtcaattagc cgcttcttta tgcacaaaag aaaaatatga
     6181 tatagacgga ttgatcgccg taaaaatcga tccgttggaa atgatctatt acaacaaaga
     6241 tggcagccgc gcgccgatgt gcggaaatgg cattcgctgt tttgctcgat acgtaaatga
     6301 tcagaacatg atgaatgaac aggaattcaa cgtagagaca ttagcaggca caagaaaaat
     6361 tacggtgttg gatccctcac ctttttattg cagcgtagat atgggagtgc cagatgattc
     6421 tccggaaaaa atcaaagcta atcaaactta tccaataaaa aaccaggaaa tagagatcaa
     6481 tggtgaaaaa gtaacgatca ctagtttatt tttaggaacg attcataccg ttgtttttgt
     6541 tgaaaatgcg cgtgaggaag tctggagaaa aagaggtgaa ctgatctgtc atcatccttt
     6601 gttcaaagaa aaaaccaatg tcaactttgt agaagtagtc aatgaacaag aattgatcgt
     6661 ccgtacctat gaaagaggag taggttggac acttgcttgc ggtacaggtt gctgtgcctc
     6721 ttatgtggtt gctaaggaaa ctgggaaaat ttcagcagat caggtagttg ttcacttgga
     6781 acaaggagac ttgatgatct ctggtgagga tgcgatacaa atggctggcc cagcagttca
     6841 tgaatggaca agaatattgg aggaatgaag atgataaaag gttcgatcgt ggcgctgatc
     6901 acgccgatga atgaagaggg atcagtagat tatgctggtt tggaaaaatt gatccaattc
     6961 catttagatg aacaaacaga tggattatta gttttaggta caacaggaga atcttctacg
     7021 ctcacacaat ctgaggagga gcagatcctt caactgacag taaagaaagt ggctggccgt
     7081 gtgccggtga ttgcaggagc tggaacgaat aatacgaaag aaacgattga aaaagcgaag
     7141 cattttgctt ctttgggggc agacgcactt ttggtcatca ccccttacta caacaaaaca
     7201 agtgatgcag gactagctgc tcattttaca gcaattgcag aagcctcacc gattccgctt
     7261 attttgtata atgttccttc tagaacaggc atgtcgattc caatccatgt attagtaaat
     7321 ttagcagaac atcctaatat cattggtttg aaagaagcct caggagatat ggcttatgtg
     7381 atggatgccg ctcggttgat tggagaagaa ttcttccttt acagtggaaa tgatgatttg
     7441 atcctaccag taatgagtgt aggaggaagc ggtgtaataa gtgtatgggc gaatatccaa
     7501 cctaaaatag tccatgaatt agtaaaagat acgcaggacg gaagatggca gcaagcaaaa
     7561 gaaaagcaat taaatgcact tgaactgatc catgccttgt tcagtgagac caatcctatt
     7621 cctgtcaaag cagccatgtc attattagac ttaccttccg gacctctacg cctgccttta
     7681 gtttctcttt caaaagagaa aaagaaacaa ttagctcagc ttttgttaaa agaaaggacg
     7741 gttgaaaaat gaaaatcgga ctgattggca gtggacagat gggaaataga gtcgaagaag
     7801 ttgcacaaga aagaggagat acggtccttc ttttacggac ggcacctaaa gaagcaacta
     7861 cgcttgcttt tacggaactg ccagaactgc ttattgattt ttctcatcca gataatttag
     7921 agaaaatcct ttcgtatagc ttatcatatc aacttccgtt agtcattggc acgacaggtt
     7981 atacacaatc acagttccaa gaaataaaag aacatgccaa acatgtacct gtgatgtata
     8041 gtgctaattt ttcgttcggc atcatggtga tgaatcaact aatcaagcaa gcagctgcaa
     8101 tgttgcaagg ctggcagatc gaactgattg aaaaacatca tagtcgtaaa aaagatgcac
     8161 catctggtac tgcaaatatg ctgcttcaaa caatccaaga agtgcaaaag ctgcagcccg
     8221 tatacaactg gcaagggaaa aaaagagaag aaaaccaaat tggtgtacac agtattcgtg
     8281 caggttcttt acctggtgaa catgatgtat tgtttgctgc tactgatgaa atatttacga
     8341 tcaaacatga atctttttct aatcgaatct ttgctgcagg cgcagtagaa gcagcggact
     8401 ggttgaaaga tcagtcacca ggttattaca aattagaaga tttattaatg gacaaagggg
     8461 tgtaaaaaac gtggaagctc aagaaatcat ccgctacatt caaacggcat ctaaaaagac
     8521 gcctgtgaaa gtctatctga atgtaaccga gccaatcgaa tttaaagaaa gtaaagtttt
     8581 tggtgaagga agcagcttcg ttgtttttgg tgactatgag acgattgctc cggttttaga
     8641 agctgaatca gaaaaaatca ttgaaatcga aatcgaaact gctgcaagat acagcgcagt
     8701 tcctttgcta gatattaaaa aaattaatgc tcgtatcgaa ccaggtgcta ttatcagaga
     8761 tcaagtgtca atcggcaaca atgccgtgat catgatggga gcgattatca atattggtgc
     8821 agtaatcggt gaaaacacga tgattgatat gggtgctgtc ttaggtggac gagcgacagt
     8881 gggcaaaaac tgccatattg gtgcaggagc tgtcttagca ggtgtgatcg aaccagcatc
     8941 ggccaaaccg gttatcgtag aagacggcgt actggtaggt gcgaatgcag tgattgttga
     9001 aggtgtccat atcggaaaag atgcagtcgt ggcagcagga gcagtggttt tagaagatgt
     9061 ggcagcagaa actgttgtcg gtggaatacc tgcacgtgta ttaaaaataa gtgatgatca
     9121 gacaaaagaa aatacagcat tgattgctgc gttacgcgaa ttatagagga gatggagaaa
     9181 aatgcgcgaa atagatacct gtattgtggg ggcaaccgga ttagtcggcc aaacgatgct
     9241 caaagtgtta gaagaatatg attttccagt aggacgattg aaattattag cttcaaaacg
     9301 ttcagccggt aaagtttgtg tattcaagaa aaagaaacac actgtacagg aattgacaga
     9361 aacttcattt gaaggatatg atttagcgct attttctgca ggtgcttctg tatccaaaga
     9421 gtttgcgcca atcgcacgaa gtcagggact atttgtcata gataattcct cagcatggcg
     9481 ggaagattcg gatattccat taatcgttcc agaggtcaat ctggaagact atacattgaa
     9541 tcggctgatt gcaaatccaa attgttcaac cattcaagcg gtacttccgc ttaaagcttt
     9601 acaagaagcc tttggtatcc agcgagtcaa ttattcgacc tatcaagcag tttctggttc
     9661 cgggcaaaaa ggcattgaag atcttcatcg tacgcaaaat gacgaggaac cagttttgta
     9721 tccttataat attagccaaa cggtgattcc ggaaatcgat cagcctttgg aaaatgggta
     9781 tacaaaagaa gaacagaaaa tgataaatga gacccgtaag attctgcatc agcctgcttt
     9841 gccagtatca gcaacctgcg tacgtgtgcc aatcgaaaat ggacatggag tctctgtggc
     9901 agttcaactg caaaaagagt ttacgacgga agaaattaga gagtgtctca gccagtttcc
     9961 agggattcaa ttagaagatg atctagcagc acataaatat ccgacgagca ttcttgctag
    10021 aggaacagat atggtttatg ttgggaggat cagaaaagac acttctttag agaacggatt
    10081 gttgttctat acgactgccg ataacatacg caaaggagcc gctgcgaatg ccgtacagat
    10141 tgctgcagct ttaatgcaga aaatagcgga ggtggcaaga tgagtaatac gctgaaagta
    10201 gcgaaattcg gcggaacatc gatgtctcat gaagagcaat tcaaaaaagt ccgtacaatt
    10261 gttctttcag atcccaatcg ccaagtgatc gttgtttctg ctttaggcaa acgtacgtca
    10321 gatgatgaca aagtaacaga cttactttat ttgatttatg cttaccttca gcatcatgtt
    10381 gattggacac ccctttggaa aaggatttgt gatcgtttca ttcaagtaag agatgttctt
    10441 gccctgcagt tacctattga agatgaacta gcacgcatac agaaacaact ggaagacgaa
    10501 aagataactg aagattattt agtaagtaga ggtgaatatc tgactgctca actgatggct
    10561 gagtatcttg gttaccagtt tattgacgca aaagacctga ttttctttga ctatgatggg
    10621 aaaatcgatc aggaaaaaac agcacaggaa atcacaaaag catttaaaag atatccgaaa
    10681 atggttgttc cagggtttta cggggcgaac cctgcaggaa aagaaaaatt attgggccgt
    10741 gggggaagcg acattaccgg cgcgatactg gcgaagatgt tgcaagcgga aagttatgag
    10801 aattggacgg atgtttcagg aatcatgatg gctgatccgc gaatcatcga tcatcctaaa
    10861 atcatcgagg aaatctcttt tagagaactg agagagatgg cttatatggg ggctaacgtt
    10921 cttcatgaag cagctgtttt cccagttcaa gaggctgata tccccatcca aataaaaaat
    10981 accaatgatc ctttcgctca agggacaaaa atatcgaatc acgaaataga aaaggaaaat
    11041 ggactgacag gaatagctgg acgcaaggat tttctttcca tcactttatt caaacgtcat
    11101 atgtccgatg aaatcgggtt tatctggaaa gcaatgagca tttttgctaa acatgagata
    11161 tcaatcgaac atattccttc agggatcgac aatatcggag tgatcgtctc agcagaagcg
    11221 attgccgata agttatttct catcacgaaa gaattaaaag aaacacttgg cgtggaagaa
    11281 atcgtcgtga tcgaagactt agctttgatc tctgtcgttg ggggtccgca taaagaattg
    11341 attggattat ctgggaaagt gttatcgata ttgaacaaat tagaaattcg cacatcgatc
    11401 ttatcacaag gagcacagga gttgaatctg atcatcggtg taccgaataa tcaatatgaa
    11461 acagtagtga agggtatcta tgaagggatg gtgaatacgg atgctgaaag aatatcgaat
    11521 ggcactccat caaattcctg aaatcgggtt tcatgaattc aagacaaaaa aatatttata
    11581 tgaacaagta aaaaacagcg aggccgttat ccatgaaatc ggcgaaacag gactactcct
    11641 ttattttgat aatcagcaag aagaaacgat tgcttttcga acagatatcg atgcactgcc
    11701 agtcaaagaa gaaacgaatc tctcttttgc ttctaagcat gaaggttata tgcatgcatg
    11761 tggtcatgac ggacatatgg cgatgctttt agggttgact gactttataa ctaaacacat
    11821 tgaggatctt atttataatg tagtactgat ctatcagcca tcagaagaaa tttccggtgg
    11881 cgcacaaagc gttattcagt caggattgtt ggataaatat gaagtacaag caatatttgg
    11941 ctttcatcta tggcctggac tagctaaggg agaagttttc tctcgaccag gacctttgat
    12001 ggcacaaagc agtgaaacag acattatcat taaaggccag tctgcacata ttgcttctag
    12061 tgaaaaagga atcgatagtc tggaggcagc tgtacgattt ttgaagaatg tttatgattt
    12121 tgaccggcaa ttaccggcag agtggaatca tctaatgaaa tttggccaaa tccaaggtgg
    12181 aacgatccga aatgttttag ctggagaagt tattgtatcc ggaagtatcc gttcttacag
    12241 ttcagatatg caaaattatt tgaagagggg attagaccat ttagcagaac agtttcactc
    12301 tacagctact atttcttttc gctataatga cggctatcca gctgtaatca accatagagg
    12361 cttatatgca gcactgttag attcaaacaa actacatgaa ttagatgctc cagttcttca
    12421 agccgaagat tttggcatat atacgcaaca atatccatgt gtatttttct ttttaggtgt
    12481 cggtgatacc cctgctttac atgatccgac gttcgatttt gatatggatg ttttagaaaa
    12541 tggtgtagaa tggtacaaaa cgattctttt tacagaaaat cttcttgtaa aaatcgatag
    12601 cagttcaaaa gaggagcgag taaataatga tgaatttatc caatcgattt agtcctaggc
    12661 tttctagaat agaagtatca aaaatacgac aattcgatca gcaaatatcg tcgataccag
    12721 atgtgatcaa actcaccctg ggagaaccgg attttccaac tcctgaacat gtcaagcaag
    12781 caggaatagc agcgattgaa gaagactttt ctcactatac cggaatgaga ggattagagg
    12841 aactgcggga agcggcttgt atatttcagc aacagcgtta tggattaact tatgatccgc
    12901 aaacggaagt tttgacgaca gttggtgcaa cggaagcgat tgcctctgcg ttgttatctg
    12961 ttttggaaga aggagacaag gttcttattc cagcgcctgc ttattcagga tatcagccat
    13021 tagtggaact agctggtgct gaattgatcc cgatagatac ttctgacaca gggtttgtct
    13081 gtcagccgga acaatttgaa cgagcatttg aacaatatgg atcagctgtc aaagcagtca
    13141 ttttaaacta tcctaacaat cctactggga cgacattgtc tgcaaaacaa ttgaaagcaa
    13201 tcgctgaggt tttaaaaaaa tatccggtat ttgttataag tgatgaagta tatgctgaat
    13261 tgacttatag tggaacgcat atgtccatag ctacttatct tccagaacaa acaatcgtga
    13321 taagcgggtt atccaagtca catgcgatga ctggttggcg agtgggcttt atttttgctc
    13381 aaaaagccct tattgacgaa ctaattaaag tccatcaata tctggtgact gccgctacaa
    13441 cgatgtcgca aaaagctgcg gctgaagcgc taataaatgg ggtgaaagat agcgagaata
    13501 tgaaagagca atatcaaaca cgaagagact atctggtcca gcaattggcg cctttaggat
    13561 ttgaagtgac ccagccaaac ggtgcatttt acttgttttg caaactccca gctgccattc
    13621 aaactgactc ttggcagttt tgtgtagaat tagcggaaca ggcaaaagtt gcgtgtatcc
    13681 caggaattgc atttggccca gaaggagaag gttatatccg gatttcttat gctagcagca
    13741 tggaaaaatt acatgaggcc tgcaaacgga tcaaagactt tttaacagaa cagtgattca
    13801 tagattttat caaaaaaaca atcgttaatt ttgcggtata ttctgcaagg agacgattgt
    13861 tttttaaatt tagttcaaat gaacgcgttt cttttgattc ataactaatg taatgttaag
    13921 tttaaattgt ttagaatgat tttaaaagaa tattcaagga ggtttcatca atggaaaaaa
    13981 tcaaagttgt cattgtaggt gcatctcatg gagggcatca atcgatcttg gaactattga
    14041 cacgatacgg tgaaaatgta gatatcacgc tatttgaagc aggagactat atttccttca
    14101 tgtcatgtgg tatggagctg tatttagaag acaaggtaac agatgtaaat gatgtacgta
    14161 atttcagacc agaaaacttt ccgcaatcca atgttcatat tttaaataat cacgaagtaa
    14221 aaacgatcga tgccgataaa aaaacagtaa cggttactag cgcatcagat aacgaaacaa
    14281 aagaatatcc ttatgacaaa ttgattttga gttctggtgt caaaccaaac aatctgccag
    14341 taccaggagc agatctagaa aatgtctact tgatgcgtgg atacaattgg gcaaccaaaa
    14401 tcaaagaaaa attaaatgat ccggctatta aaaaaatcgc tgtcgtaggt gcgggttaca
    14461 ttgggatcga agcagcagaa gcaagccgaa aagctgggaa agaagtcgta ttgcttgatg
    14521 tgatcgatag acctttaggc acttatttag atgctgagat gacagatatt ttagaacaac
    14581 acctaaatga aaacggtatt gaagttttga caaatgcaaa aatcgaagct tttactggta
    14641 acggaaaagt tgaggcaatc aaaacaagtg aaaaagaaat cccagcagat ctagtcattc
    14701 aagctgccgg tgtgaaggca aatacagaat ggttaaaagg gatcgtcgac ttagatgaac
    14761 gtggctggat ccaaacaaat gaatacttgc aaacgaatct tccagatgtg tatgcagtag
    14821 gagatgctac acttgcttat tctatcccag cacgcaaaaa aatgccgatc gctttagcga
    14881 ctgttgcacg tagagaagca cgttatgtag taaaacatct ttttgaagaa gtaccaaaca
    14941 aaccgttcgg cggagtcgta ggttcctctg cattaagtgt ctttgactat cattttgcag
    15001 caagcggatt gaatagcttt acagcagcaa aagcaggagt agatgtacga gtgtcttatt
    15061 atgaagatac gttacgacca aaatatgtac cagaagaaca aggaaatcca aaagtgtcca
    15121 tccaattatt ctcggatcca atgacccatc aattgctagg aggagcagta ttatctacct
    15181 atgatgttac aggtcaagga aatgtattgg cactagcgat ccaaaacaaa ctgactttag
    15241 aagaactagc agaagctgac ttcttcttcc agccaggctt tgaccgacaa tggagcatgt
    15301 tgaatctagc cgctcaacaa gcgttaggag aagaaccatt tgtagaataa gaaaacgaaa
    15361 tatttgaaaa gaggttgtga aaaagctgcc ttgcatcaag taataagaac agccaagtaa
    15421 aaacagcttc ttatgttttt aacttggctg gacttattac cgcagatgca agcttttgaa
    15481 caccgtttat tttcaaaaaa gggactgtga cacgatttgt gtaccgaccc ccaaaagtta
    15541 gaccaaaaaa tctaactttt ggaggtcggt attttttatg gttaaatata cttttgaact
    15601 taaattaaag atcgttcatg attatttgga tggcaaaggc gattggaccg taaaaatcca
    15661 gatcaagaga ttgaagcgga aatgcttaaa attcgggaga agcacaagga ttatggctgt
    15721 ttacggatga ccaatgaact aagaaaccgc ggtttctcta tcaataaaaa gaaagttcag
    15781 cgcttgatca agaagctagg aataaaagta acggcataca cgcgtaaatc acgtcgctac
    15841 aattcttatc gaggaaaagt
//
LOCUS       DACGEU010000064        15355 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.064, whole genome shotgun sequence.
ACCESSION   DACGEU010000064 DACGEU010000000
VERSION     DACGEU010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15355)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15355)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15355
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.064"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            110..445
                     /locus_tag="IXR40_001939"
     CDS             110..445
                     /locus_tag="IXR40_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361776.1"
                     /translation="MPAFYEVKMMYRNPKNIKQEIKLFFFYLVDLGIVAGSVMASVYF
                     AKLMPISPMMKFALYLLAFVVGVWMCVRTPNHPKERNILMLYYLFKMDRNRYHEVEFK
                     RNSRGKIEL"
     gene            442..1059
                     /locus_tag="IXR40_001940"
     CDS             442..1059
                     /locus_tag="IXR40_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361777.1"
                     /translation="MIVAESNENKLSGVFDKFLELVIPKDKDMCELLPYKKILKDGTL
                     VTNDNKYQAFFKVKTTDLTSISEDGFMRMVNKLTYLNRVYLEPYKIYSLTYPTETVNQ
                     AIYWKHRIQEAKRSLLSNNDPNLETYLKWNLKLAYDNYERVDLVSTLPELMFVICVYG
                     KTQKEVKNHADVMKQAGGRELDLQRITEGDLINVITKLMNPNTSL"
     gene            1075..1542
                     /locus_tag="IXR40_001941"
     CDS             1075..1542
                     /locus_tag="IXR40_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361778.1"
                     /translation="MLKHCRKGFCKVIKGKNAADLIFEWKESNLINVRGKNGSGKTER
                     VMASIDNSRPRSRALVITDEKNHYKGIRTIEKKYLTNNDLKVVDDILNIYPDFNLVVF
                     DETIPVTEIKGFYQSFSNLANKYEEVLFVWITEEDSNSKSAFFSEKNAFLHSI"
     gene            1558..3513
                     /locus_tag="IXR40_001942"
     CDS             1558..3513
                     /locus_tag="IXR40_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tra protein"
                     /protein_id="HAQ4361779.1"
                     /translation="MIVSKKLARNLVSEGYDLRLVEKYQPSGGIKFDERYISTGDGYV
                     TSIAVIEFAEDVNSRWLTDIMAIPNTIATFDVCTADKEDLLHKINTSIGELDYRSTNE
                     NRTTDKTDALLDKYNLEDFAQEITKRGEVVKTVHARIFVYSDSLEELEKRISEIRKDL
                     ASVNHKAIVPQFRMKDEWMSLFQDGMEQESKLFAKKGLTVPAKNIGGGIPFHHKSLKD
                     PRGFYLGTTSTGGAFIFDPFYSTKQRRSFNGFILGKMGFGKSTLIKQLQEGLQAKNCF
                     IRGFDKSGEFEGMVKKAGGVYVDLGGGDMVVNPLQIYATVMKKDQFGNDVVDESKSFQ
                     NHITKCSNQIRFLEPEIDTATVREYTLMLQDFYIHYGILPKEWREARDDNERNQLNTN
                     ICNLPNDSYPIYGEFLKFIENQQFKIKNATPERVRSIELIKLIVTDMCTTYPQIFNGV
                     TTMPNFDTTKIVYYNIDSISKMSAPVFHCQLFTALTTIWNSALQNGKIQKENFKKYGS
                     DYYKYAQDFMVLIDECHNVINSNNKYACEYVLSFEREMRKMRAGVYFATQTPEEIIPK
                     DSGSEVADVIRNIFNLCTFKCFFNLDSALLEDIKKVLGNTITDTEIMLLPELEVGQAV
                     VQTSSEDTYMINFDPYPEQIERFDGGQ"
     gene            3535..4671
                     /locus_tag="IXR40_001943"
     CDS             3535..4671
                     /locus_tag="IXR40_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361780.1"
                     /translation="MEQNKNNNVASTLARQGMKQVSKKIGLALKIKIGVVIGLITLVG
                     LLVIGSLATLQGTQTATNTGGAEVIGGNKPLSPEVQKWQKTVEKYAEKYGIKELVPYA
                     LAIMQCESGGKLPDLMQSSESAGLPVNTLQYEESIDQGLKHLSNVYNIAKSYGMESNY
                     DGIVQAYNYGIAYMHYLGKNKKTHTIETAEAYSKNVVAPSLGNTTGQTYSYVNEVSIK
                     YGKTYLYLNGGNFYYAELVKQYIGGGSGNPANPSEFWGKMKTEMEKYQGWPYVWGGKN
                     PTTGFDCSGLTAYLYQFSAGITIDSYTVTQYEATEAVSIKEAKAGDLIFFRGTYGAPD
                     FISHVGIYVNETTMYDSNSSGIGYHNWQDSYWQSHSPEIRRVKK"
     gene            4686..5336
                     /locus_tag="IXR40_001944"
     CDS             4686..5336
                     /locus_tag="IXR40_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HAQ4361781.1"
                     /translation="MIKRKNDNKWKYICGVLIIILVLGGLLSQLHTSNIQAKNKKLDQ
                     EVTQLEEQNSKLSKNISDLNANVEANLTNDDGSELNKQIAEVAKKFVELYPVYDIEKV
                     EEKKADLEKIATPSVADSIVPDDMITTSKKTLESKSTTQKGEAYSSDPTFKSKYKDSK
                     LYTNYVNANTINYFAEVNYKTESSSGDTENTVYMLFEVTNKDGQVLVDNYEIKYLK"
     gene            5350..6246
                     /locus_tag="IXR40_001945"
     CDS             5350..6246
                     /locus_tag="IXR40_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361782.1"
                     /translation="MNKKYSIHNKKEPNKKNKAQIDKVYKKTKGVKLYLGAILGFLAI
                     GMIIVFSPYVMGKSYDFETVKMSSAQNVTSSLNMYVDDMEINREAGLFKLVLRYQDDT
                     GTKSLSNIKSDYKLNFITNKNNEDVKTKVVKLSDEYTVIYYQNLPKDFGVISVTVNPR
                     YIYPELEPSNDLKEKEIKFYAVDKDIKSNAKLEVESTSDLQKDNFKYQIKAIENSIKD
                     EKKSIEKMNLANKVVQKDIDKANQNLEFQTLDEQTDTKNEISSMQTTIENNKSSIEES
                     ENKIKQFEEKIKQLEKSASRFE"
     gene            6282..6512
                     /locus_tag="IXR40_001946"
     CDS             6282..6512
                     /locus_tag="IXR40_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361783.1"
                     /translation="MCNSIVTIQEKAEEELMRIEAEYKEKRKAIKRKKNAELKKYKEE
                     QALKLGMMLCKYYDCYDINEVLKKANLNQFCE"
     gene            6863..7159
                     /locus_tag="IXR40_001947"
     CDS             6863..7159
                     /locus_tag="IXR40_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361784.1"
                     /translation="MDVSIRGIDPQYVKEIDKKVNKIQERTGKKFSRNDYFLAIIRQD
                     SEIDLIDYKKSEFDLVVEKLLLSNEQMVESISELTSVYERLFNFLISERSDLNK"
     gene            7156..7623
                     /locus_tag="IXR40_001948"
     CDS             7156..7623
                     /locus_tag="IXR40_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361785.1"
                     /translation="MNYPYFKVSATEDVKEKFNKCFEVNKSVFQTKSNMFRYVVSNLP
                     MLTKANQNFRDPEKEELAKNLEEAKLKISELETIIELQKQQLENFNKKEDSTHKDYSE
                     QLNSIEESVYKLLINSGLASKELEEERAEPEQESSRLGEGTMFSSPSLRFTTD"
     gene            7690..9225
                     /locus_tag="IXR40_001949"
     CDS             7690..9225
                     /locus_tag="IXR40_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361786.1"
                     /translation="MVGDDMTEHIFNRKSASIILKAKFETGKSKKNNHMVELQKFVDY
                     ISRQEAIRQDKLDHDYSEDELNELARIEKALEKIEQETDQPVIKDLREMDKYIDYMTR
                     KKAILENVDNEIVNGAFSNTKRYITKKDISKIKESVIEAKNNGSVMFQDVISFDNDFL
                     VREGYYNPETNELNENVLYEATKSMMGKMQEKEELVDPFWFATIHRNTEHIHIHVTAM
                     ERKNTREIMEYDGVLQARGKRKQSTLDDMIFKFGSKILDRTNEFEKISKLRKEVPLEL
                     KQSVKDSLIQLYVENNSRYDKELVKYLKELKKEIPSTTRGYNELPEETKEKIDEVTNY
                     MTKDNPKRKEYDRMTKEIDELYQTTYGKRYNPQEYYLNRKKDFNARMGNAVVGQIKLL
                     KQSEEKNLKSNELKNLLDGKKLNVKFDREKPEFKTKYAKQSYDDFQKRLEERQLAREK
                     NEVHFKKISEKFKDKKLIRKIDRVINDDLNMYRAKNDYEVAQRMIEQEKMRQAREFEI
                     GMN"
     gene            9247..9576
                     /locus_tag="IXR40_001950"
     CDS             9247..9576
                     /locus_tag="IXR40_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361787.1"
                     /translation="MKNFDIVCSNTKNIYLRELLNSDSETIEDVKKIIVLFEKENMEL
                     ENWGLFEIPISGNYCFYNWKTEDDVAFANYFFDKNYFSPLYIDKHSNEQVASSIKEAI
                     KLERVRK"
     gene            9578..9841
                     /locus_tag="IXR40_001951"
     CDS             9578..9841
                     /locus_tag="IXR40_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361788.1"
                     /translation="MIDFRTVMDKLSNGDFRVLIELYLNVTSTVKEFLYSNPKTALVL
                     VAVLIVFAVISFIKKMIPLLIIGAVLILGLYFPEVLDQIKNIF"
     gene            10016..10882
                     /locus_tag="IXR40_001952"
     CDS             10016..10882
                     /locus_tag="IXR40_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361789.1"
                     /translation="MKKLRVIATIPMIFSFALLLSACGKEEAGAKSNEAHNISFIDSA
                     EQKDSRCWLVVETSSKNKTPIDKNEYVKAVIQTKDGKAKVFKTDMEQLTLEKVSKMSD
                     EEIIEQALNADKQKFNDKKKSDIDSYNATLDSVKTELENEEKQEFQNDQKIADFQDSI
                     PKIQADIEEIDGVQYSEPEWKMVSATIKMDNENKSPSMETVKLSYKYLDSPIWNLNSF
                     GEVSSEGELSYESTSMDLKLSIPVATTKVLDNFYSGYSNDELDQLLLTKVASKDNKVQ
                     LDSKGKNVSIVE"
     gene            11238..11735
                     /gene="dfrG"
                     /locus_tag="IXR40_001953"
     CDS             11238..11735
                     /gene="dfrG"
                     /locus_tag="IXR40_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HAQ4361790.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            complement(11807..13759)
                     /locus_tag="IXR40_001954"
     CDS             complement(11807..13759)
                     /locus_tag="IXR40_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HAQ4361791.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(13766..14062)
                     /locus_tag="IXR40_001955"
     CDS             complement(13766..14062)
                     /locus_tag="IXR40_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361792.1"
                     /translation="MQIGVLKWLQFTKQKGVHFPMQFLEPKNKNAKSVDWEISEQVRV
                     IVKQYAEYAERTESEAVDEFLLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            14404..14694
                     /locus_tag="IXR40_001956"
     CDS             14404..14694
                     /locus_tag="IXR40_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361793.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
BASE COUNT         5791 a         2048 c         2803 g         4713 t
ORIGIN      
        1 caagacgaag attcacttat gaagacaacg aattattcag agatacactt aatgatccta
       61 atccactttt cgataattta aattaaatta aaagccggca tgagtgatta tgccggcttt
      121 ttatgaggtg aaaatgatgt atagaaatcc caaaaatata aaacaagaga taaagctatt
      181 tttcttctat ttagtcgatt taggaatagt agccggaagc gtgatggcaa gtgtttactt
      241 tgcaaaatta atgccaattt caccaatgat gaaatttgca ctgtacttat tagcatttgt
      301 agtgggtgtt tggatgtgcg ttagaacgcc taatcaccct aaagagcgaa atattttaat
      361 gctgtattat ctctttaaaa tggatagaaa cagataccac gaagtagagt ttaaaagaaa
      421 tagtaggggg aaaattgaat tatgattgtt gctgaaagta atgaaaataa attaagtggt
      481 gtttttgaca aattcttaga actagttatt ccaaaagata aagatatgtg tgaactttta
      541 ccatataaaa aaatattgaa agacggaacg ttagtgacta atgacaataa gtatcaagcc
      601 ttttttaaag ttaaaacaac tgacttaact tctatttcag aagatggatt tatgcgtatg
      661 gtaaacaaac tcacttattt aaatcgagta tatttagaac catataaaat ttattcatta
      721 acttatccta ctgaaacagt aaatcaagcg atttattgga agcatagaat acaggaggca
      781 aagagaagtt tattgagtaa taatgatccc aatttagaaa cgtatctgaa gtggaatcta
      841 aagctagctt acgataatta tgaaagagtt gatctagtat cgactttacc agagttgatg
      901 ttcgttattt gtgtttatgg aaaaacacaa aaagaagtga aaaatcatgc cgatgtaatg
      961 aaacaggccg gtggtagaga attagattta caaagaatta ctgaagggga tttaatcaat
     1021 gtgataacta aattgatgaa tcccaatact tctttataag gcggtgctta ttatttgtta
     1081 aagcactgta gaaaaggatt ttgtaaagta attaaaggta aaaatgctgc tgatttaatc
     1141 tttgaatgga aagaatctaa tttaattaat gtacgtggga aaaatggaag cggaaagaca
     1201 gaaagagtga tggctagtat tgataattca aggcctagat caagagcatt agtaataact
     1261 gatgaaaaaa atcactataa aggcatacga acgatagaaa aaaaatattt aactaacaat
     1321 gatttaaaag tagtagatga tattttaaat atttatcctg attttaattt agttgttttt
     1381 gatgaaacaa ttcctgtgac agaaataaaa ggattctatc aaagcttttc caatctagca
     1441 aataaatatg aggaagttct gtttgtttgg attacagaag aagatagtaa tagcaagtca
     1501 gcgttcttta gtgaaaagaa cgctttttta cattctattt aaaaaggaga attgaacatg
     1561 attgtaagta aaaaactagc aagaaatcta gtaagtgaag ggtatgactt aagattagta
     1621 gaaaagtatc aaccgagcgg tggaattaaa tttgatgagc gttatatttc tactggtgat
     1681 ggatatgtaa cttcgattgc tgttattgag tttgcagaag atgtaaatag tcgatggtta
     1741 acggatataa tggcaattcc aaatactatt gcaactttcg atgtatgtac ggcggataaa
     1801 gaagacttat tacacaaaat caatacgtct attggagaat tagattaccg atcaacaaat
     1861 gagaatagaa caactgacaa aacagacgct ttactagata aatacaattt agaagatttt
     1921 gcacaagaaa ttacgaaacg tggtgaagtt gtcaaaactg ttcatgctcg tatttttgtt
     1981 tatagcgatt ctttagaaga attagagaaa agaattagtg agattcgtaa agatttggct
     2041 agtgtcaatc acaaggcaat tgttccgcaa tttagaatga aggatgaatg gatgtcttta
     2101 tttcaagatg gcatggaaca agaatcaaaa ttatttgcca agaaaggctt aactgttccg
     2161 gcaaaaaata ttggtggcgg tattccattt caccacaaga gtttgaaaga tccacgtggg
     2221 ttttatttag gaactacgtc aactggtggt gcttttatat ttgatccatt ttattctacg
     2281 aagcaaagac ggtcgtttaa cggctttatt ttaggaaaga tgggttttgg taagtcaact
     2341 ttaattaaac agctacagga aggcctacaa gcgaaaaatt gttttattcg aggatttgac
     2401 aagtcaggtg aatttgaagg catggtgaag aaagcaggcg gtgtatacgt cgatttaggc
     2461 ggtggtgata tggtagtaaa tccattgcaa atttatgcaa cagtcatgaa aaaagatcaa
     2521 tttggaaatg atgttgtaga tgaatcaaag agttttcaaa atcatatcac taagtgtagt
     2581 aatcaaattc gctttttaga acctgaaatt gatacggcaa ctgtacgtga atatactttg
     2641 atgttacaag acttttatat tcattatgga attttgccaa aagaatggag agaagcgaga
     2701 gacgacaacg aacgaaatca attaaataca aatatttgta acttgcctaa tgattcatat
     2761 ccaatctatg gagagtttct taaatttatt gaaaatcaac aattcaaaat taaaaatgct
     2821 actcctgaac gtgtccgttc tattgagcta attaagctta tcgttacgga tatgtgtaca
     2881 acttatccgc aaattttcaa cggagtaaca acaatgccaa actttgatac aacaaaaatt
     2941 gtttactata acattgattc tattagtaaa atgagtgccc cagtattcca ttgccaatta
     3001 tttacagcgt taacgactat ttggaacagt gccttgcaaa acggaaagat tcaaaaagaa
     3061 aactttaaaa aatatggcag tgattattat aagtatgcac aagatttcat ggttttgatc
     3121 gatgagtgtc acaatgttat caattcaaat aacaagtatg cttgtgaata tgtactaagt
     3181 tttgagcgag aaatgcgaaa aatgcgtgca ggtgtttatt ttgcaactca aacgcctgaa
     3241 gaaattatcc ctaaagattc tggatcagaa gtagcagatg tgattagaaa catttttaat
     3301 ctatgtactt ttaaatgctt ctttaattta gattctgcat tgttggaaga cataaaaaaa
     3361 gttttaggaa atacaattac tgatacagaa attatgcttt taccagaatt agaagtagga
     3421 caagctgtag ttcaaacttc cagtgaagac acctatatga ttaattttga tccatatcca
     3481 gagcaaattg aacgattcga tggtggtcaa taatagaaat cggaggtgaa tttaatggag
     3541 cagaacaaaa ataataatgt tgcttcaaca ctcgctcgtc aagggatgaa gcaagtatca
     3601 aagaaaatag gtcttgcttt aaaaataaaa ataggggtag ttataggact gataacattg
     3661 gttggccttt tagttatagg ttctttagct acattacaag gaacacaaac tgcaactaat
     3721 acaggaggtg cagaagtcat tggtggcaac aaaccgttgt cacctgaagt tcaaaaatgg
     3781 caaaaaacgg tagaaaaata tgctgaaaaa tacggaatta aagaattagt accttatgct
     3841 ttagcaatta tgcaatgtga atccggaggt aaattgccgg atttaatgca aagtagcgaa
     3901 tcagccggat tgcctgtaaa cacacttcaa tatgaagaaa gtatcgatca agggctaaaa
     3961 catttgagta atgtgtataa cattgctaaa agttatggca tggaaagtaa ctatgatgga
     4021 atagttcaag cttacaatta cggaatagct tacatgcact acttaggaaa aaacaaaaaa
     4081 acacatacta tcgaaacggc tgaagcctac tctaaaaatg ttgttgctcc aagtttagga
     4141 aatactacag gacagactta ttcatatgta aatgaagtat caattaaata tggaaaaaca
     4201 tatttgtatt taaatggtgg taatttttac tatgcagagt tagttaaaca gtatatcggt
     4261 gggggtagtg gtaatccggc taatccttca gaattttggg gaaaaatgaa aacagaaatg
     4321 gaaaaatatc aaggttggcc ttatgtttgg ggcggtaaaa atccaacgac aggttttgat
     4381 tgtagcggat taacagctta tctttatcaa tttagcgccg gaattacaat agatagttat
     4441 acagtaacgc agtatgaagc aactgaagca gtatcaatta aagaagcaaa agctggtgat
     4501 ctgattttct ttagaggaac atatggagcg cctgatttca tttctcacgt aggtatttat
     4561 gtcaatgaaa caactatgta tgacagtaat tcaagcggaa ttggttatca caattggcaa
     4621 gattcatatt ggcaatcaca tagtccagag attcgtagag tcaaaaaata ggaggaagaa
     4681 aatagatgat taagagaaaa aatgataata aatggaaata tatttgtggt gttttaatta
     4741 ttattttagt tttaggtgga ttgttatctc aacttcatac aagtaacatt caagcaaaaa
     4801 ataaaaaatt ggatcaagaa gttacacaac tagaagaaca aaatagcaag ttaagtaaaa
     4861 atattagtga tctaaatgca aatgtagaag cgaacttaac taatgatgat ggcagtgaat
     4921 taaataaaca aattgctgaa gttgctaaga aatttgttga gctatatccg gtatatgata
     4981 ttgaaaaagt agaagaaaag aaagctgatt tagagaaaat agctactcct tctgtagctg
     5041 attctatcgt gccggacgac atgattacaa cgagtaaaaa gactttagaa agtaaatcta
     5101 ctactcaaaa aggagaagca tattcaagtg atccaacatt caaaagtaaa tataaagatt
     5161 caaaattata tacgaattat gttaacgcca atactattaa ttattttgct gaagtaaatt
     5221 ataaaacaga atcttctagt ggagatacag aaaatacagt ctatatgctt tttgaagtaa
     5281 ccaataaaga cggccaagtg ttggtagata attatgaaat caagtactta aaatagtgag
     5341 gtgaagtata tgaataagaa atattccatt cataataaga aggaaccaaa taaaaaaaat
     5401 aaggcacaaa ttgacaaagt atataaaaaa acgaaaggag taaaattata tttaggtgct
     5461 atacttggat ttttagcaat aggaatgata atcgtttttt ctccttatgt gatggggaaa
     5521 agttatgatt ttgaaactgt aaaaatgagt tcagcccaaa atgtaacgtc ttctttgaat
     5581 atgtatgttg atgatatgga aataaatagg gaagccggac tgtttaaatt agtattgcgg
     5641 tatcaagatg atacaggtac taaatcacta agtaatatta aaagtgacta taaattaaat
     5701 tttataacga acaaaaataa tgaagatgtt aagacaaaag ttgtaaaatt gtcagatgaa
     5761 tacacggtaa tttattatca aaatctgcct aaagattttg gtgtaatttc tgtgacagtt
     5821 aaccctagat atatttatcc tgaattagaa ccttcaaatg acttaaaaga aaaggaaata
     5881 aaattctatg cagtagacaa agatattaaa tcaaatgcta aattggaagt tgaaagtact
     5941 tctgatttgc aaaaagataa ttttaaatat cagattaaag ctatagaaaa ttctataaaa
     6001 gatgagaaaa aatcaattga aaaaatgaat ttagcaaata aagtagtgca aaaagatatt
     6061 gataaagcta atcaaaactt agaatttcaa accctagacg aacaaacaga tacaaaaaat
     6121 gaaatcagtt ctatgcagac gactattgaa aataataaat cttcaataga ggaaagtgaa
     6181 aataaaatca aacaatttga ggaaaaaata aagcaactag aaaagtctgc aagccgattt
     6241 gagtgatcgt gtttaaatta ttttaaggga gtttagagag aatgtgtaat tctattgtca
     6301 ctattcaaga gaaagctgaa gaagaattaa tgagaattga agcggaatat aaagaaaaga
     6361 gaaaagcgat taagcgcaaa aaaaatgcag agcttaaaaa atataaagag gaacaagcgt
     6421 taaaattagg aatgatgttg tgtaaatatt atgattgcta tgatataaac gaagtgctaa
     6481 aaaaagcgaa tttaaaccaa ttttgtgaat agaaaagaga gtggcaaggt aaaacttgcc
     6541 actctttttt tgggcgtaaa agctttagtt actatgacca aaactacgga cgaaactatg
     6601 accaaaagta ggtactatat tatgaccgaa aataggtcga aaatggattt ttttgtgata
     6661 gcaaaaaata tgaagctatt ttgaaagaaa accagttggc acagccaact tagccacctt
     6721 cctttaggaa ggtgctatca gttttccctt atgctctttg tattaattcc ttggtcttgt
     6781 ctttaaatct ttaattttcc tttggacttt gatataataa tatataccag atagataaaa
     6841 acagcttgaa agaggtgtgt gtatggatgt ttcaatcaga ggaattgatc cacaatatgt
     6901 aaaagagatt gataaaaaag ttaataaaat tcaagaacgt accggaaaaa agtttagtag
     6961 gaatgactat tttttagcaa tcattcgcca agatagcgag atcgatttga ttgactataa
     7021 aaagtcagaa tttgatttag tagttgaaaa acttttattg tcaaatgaac aaatggtaga
     7081 aagtattagc gagttaactt cagtttatga acgcttattc aattttttaa ttagcgaaag
     7141 gagtgattta aataaatgaa ctacccttat ttcaaagtat cagcaacaga agatgtaaaa
     7201 gaaaaattca ataagtgctt tgaagtaaac aagtcagtat ttcaaacaaa atccaatatg
     7261 ttccgttatg ttgtttcaaa tttaccaatg ttaacaaaag ccaatcaaaa tttccgtgat
     7321 ccagaaaaag aagagttagc taaaaactta gaagaagcaa aattaaaaat tagcgaactt
     7381 gaaacgataa tagaattgca aaaacagcaa cttgaaaact ttaataaaaa agaagacagt
     7441 acacataaag attatagtga acaattaaat agtatagaag agtctgtcta taaactatta
     7501 attaatagtg gattagctag taaagaatta gaagaagagc gtgctgaacc agaacaagaa
     7561 agtagtcgtt tgggagaggg aacaatgttt agttcaccgt cattaagatt tacaacggat
     7621 tgaacactaa aaaattctaa tgcaacttag cattaagtac aaaaccgcct gtagaaaaaa
     7681 tttttgaaaa tggtgggtga tgatatgact gaacatatct ttaacagaaa aagtgcgagc
     7741 attattctta aagcaaaatt tgaaactgga aaaagcaaaa agaataatca catggtagaa
     7801 cttcaaaaat ttgtagatta tatttccaga caagaggcta ttaggcaaga taaactagat
     7861 catgattatt cagaagatga actaaatgaa ttagctagaa tagaaaaagc tttggaaaaa
     7921 atagaacagg aaacagatca accagtgatt aaagatttac gtgaaatgga taaatatatt
     7981 gattatatga cacgtaaaaa agctatctta gaaaatgtag ataatgaaat agtaaacgga
     8041 gcatttagca atacaaaaag atatatcact aaaaaagaca tttcaaaaat aaaagaatcg
     8101 gtcatagaag caaaaaataa tggatcggtg atgttccaag atgtaatttc attcgataat
     8161 gattttttag taagggaagg atattataat ccagaaacaa atgaattaaa tgaaaatgtt
     8221 ctatatgaag caacaaagtc tatgatggga aaaatgcaag aaaaggaaga actagttgat
     8281 cctttttggt ttgcaacgat tcacagaaat actgaacata tccatattca tgtaacagct
     8341 atggagcgta aaaatactcg tgaaataatg gaatatgatg gtgttttaca agctaggggt
     8401 aagagaaaac agtctacgtt agacgatatg atttttaaat tcggtagcaa aatattagat
     8461 agaacgaacg agtttgaaaa aatttctaag ttgagaaaag aagttccttt agaacttaaa
     8521 cagtctgtaa aagattcttt gattcaatta tatgtagaaa ataattcaag atatgacaaa
     8581 gaattagtaa agtacctaaa ggaattaaaa aaagaaatac ctagtacaac acgtggctac
     8641 aatgagcttc ctgaagaaac aaaagaaaag attgatgaag tcacaaatta tatgacaaag
     8701 gataatccaa aaagaaaaga atatgatcgt atgactaaag aaattgatga gctatatcaa
     8761 acaacctacg gtaaacgcta caatccacaa gaatattatt taaatagaaa aaaagatttt
     8821 aatgctcgaa tgggtaatgc tgtagtagga caaatcaaac ttttaaagca atctgaagaa
     8881 aaaaatttga aaagtaatga acttaaaaat ctattagacg gaaaaaaatt aaacgttaag
     8941 tttgatagag aaaaaccaga atttaaaacg aaatatgcta aacaaagtta tgatgatttc
     9001 caaaaaagat tagaagaacg acaattagca cgtgaaaaaa atgaagtcca cttcaagaag
     9061 atttctgaaa aatttaaaga taaaaagctt attagaaaaa ttgatagagt aatcaatgat
     9121 gatttaaata tgtatcgtgc gaaaaatgat tatgaagtag cgcaacgaat gatagagcaa
     9181 gagaaaatga gacaagcacg tgaatttgaa ataggaatga attagtagaa acggagaata
     9241 gaaattatga aaaacttcga tatagtgtgc agtaatacaa aaaatatata tttacgtgag
     9301 ctacttaaca gtgattcgga aactatagaa gatgtaaaaa aaatcatagt gttgtttgaa
     9361 aaagaaaaca tggagctaga gaattggggg ctttttgaaa taccgattag tgggaattac
     9421 tgtttttata attggaagac agaagacgat gtagcttttg caaattactt ttttgataaa
     9481 aattactttt ccccattata tatagataag catagtaatg aacaagttgc ttcttcaata
     9541 aaagaagcaa taaaattgga aagagtgagg aaatgatatg atcgatttta gaacggttat
     9601 ggataaacta agtaatggag attttcgcgt attgattgaa ctatacttaa atgtaacgtc
     9661 tacagtcaaa gagtttttat attctaatcc caaaacagct ttagtattag ttgcagtact
     9721 gatagttttt gctgtgatct cttttattaa gaaaatgatt ccgctattaa ttataggtgc
     9781 tgtgttgata ttaggtttgt atttccctga agttttggat caaataaaaa atatatttta
     9841 ggctctaaaa gcttccagta gaaaattttg ggctttgata tttgtattaa gcggtttgaa
     9901 atagaaattt gataaactac atgaaaagac attatataag agtatctgtg tattggaata
     9961 aaaatatgat aatataaaat tatatatcag accgataaaa aagaggtgct tataaatgaa
    10021 aaagttaaga gttattgcaa caatacctat gatttttagt tttgcgctat tattatctgc
    10081 atgtggcaaa gaagaagctg gtgctaagtc aaatgaagca cataatatct cattcataga
    10141 tagtgcagaa caaaaagact cacgttgttg gttggtagtc gaaacaagta gtaaaaataa
    10201 aacgcctatt gataaaaatg aatatgtaaa agcggtgatc caaactaaag atggcaaagc
    10261 aaaagtattt aaaacggata tggaacagct tacattggaa aaagtttcta aaatgagtga
    10321 tgaagaaata atagaacaag cattgaacgc tgataaacaa aagtttaatg ataagaaaaa
    10381 aagcgatatt gatagctata atgccacttt agattctgta aaaacagaat tagaaaatga
    10441 ggaaaaacaa gagtttcaaa atgaccaaaa aattgctgat tttcaagata gtatacctaa
    10501 aatacaggcg gatatagaag agatcgatgg tgttcaatat tcagagccgg agtggaaaat
    10561 ggtatcagca acaattaaaa tggataatga aaacaaatca ccttcaatgg aaaccgttaa
    10621 attatcttat aaatatttag atagtccaat ttggaattta aatagttttg gtgaagtttc
    10681 gtctgaagga gaattatctt atgaatctac tagtatggat ttgaagttat caattccagt
    10741 tgccacaacg aaagttttag ataattttta ttcaggatat tctaatgatg aattggatca
    10801 acttttgctt actaaagtag cttctaaaga taacaaagtt caattagata gtaaaggtaa
    10861 aaacgtaagt atagttgagt agatggtaaa ataagaaggg ataagatggt tactataact
    10921 atcttatctc ttttttattt gcattaagtc agtgaaatta gattaagtag ttcagttttg
    10981 gagtacaaaa tgacaaaatg tacttcaaaa tggactactt ttttcatttt aacttacata
    11041 ccaaattaca tacaaaatga tttataaaat gcaattgaaa atgataattg aatgaaaatt
    11101 tgtgattttg tggtattatg ataatataac ttatagaaaa aattgcttat tcaactaacg
    11161 ggcaggataa tgagaaaagg ttttttgata gaaataagaa attagatggt aaattagtta
    11221 aaaaggctgt gttataaatg aaagtttctt tgattgctgc gatggataag aatagagtga
    11281 ttggcaaaga gaatgacatt ccttggagga ttcccaagga ctgggaatat gttaaaaata
    11341 ctacaaaggg acatccgata atattaggta ggaagaacct tgaatcaatc ggaagagcct
    11401 tacctgacag aagaaatatt attctgacga gagataaggg gtttaccttt aatggttgtg
    11461 aaattgttca ttcaatagaa gatgtttttg agttatgtaa aaacgaagaa gaaattttta
    11521 ttttcggagg agaacagatt tataatttgt ttttccctta tgttgagaaa atgtacatca
    11581 caaaaataca tcatgaattc gaaggagata ctttttttcc agaagtgaat tatgaggaat
    11641 ggaatgaggt atttgcccaa aaagggataa agaatgataa aaatccgtat aactactatt
    11701 ttcatgtata tgaaagaaaa aacttattga gttaacgggt gcgttaattg aagaagaaca
    11761 gtaaagataa agcacaagag cttgggatta ctccaagctc tttttgtcat ttgaaataaa
    11821 ttatatcttt ccaatcaaat tgtttatctg taatccctaa tctttgagca ggtgtcaaaa
    11881 cctttttatc cgctgattta aaagggcgac aaaagttgta gtaagttctt agaattgtaa
    11941 tcgcaaattg agcatacttc ggattgaagt tagcgtaaat atagctcttc ttatcaccac
    12001 gagctgttgt taatggtctt tcaagagatg atatataacg tcttatctgt tgaataaagc
    12061 tattggtcga atggtcatta acatttaata gcatctttgc gatttcgttt ggttccagag
    12121 cagataaatc cgttctacaa tcaactgaat aaaatccttt atccttagtg gctaatggat
    12181 gtttgatagg gttatcggca tatttgcgat atctttctcc atctttacta atagcctctt
    12241 cgtggaattg atgacttgtt agtaattcag ttagataatg agatgccaaa gtccgtagaa
    12301 actttgtttt gaatcctctg atatctcccc aatcgagcag ttctgctttt gcttgtccga
    12361 attcttttaa gcattgtttt ctgcttttcg tcttgttaac ttggcaaata aaatgatgtg
    12421 catcgctcaa ccttaattct ttcgtgaata ctctataaaa ggcgtttcta atagagaagt
    12481 catcatcact aatcattcgc cattcgtcgg cattaaccat ttgtttaatt aaccaatagt
    12541 gagcagttgt agtataagga gcatcaacat ttaaaccatc gacaaatcta ctcctattag
    12601 taattttccc taattcgtga agataagcat tcctattttc gctatcgtta gcggatggtt
    12661 cttgtggata ataagaccaa tctaacctat catttttacg actaaaagta ttgagatggt
    12721 cttctttgaa ttttcttgta tcttcattta attcatccat tgaaatattc caatcatagg
    12781 caacatcaga acggaacaca tatcttgata agacctcagc agatacaact atatacgttt
    12841 gcatattaag gtcttcaaac cccgtatatt tctttgaacc ttgtcctttc ttacggacgt
    12901 tatttaggta gtagtgcatc ttgtccgtat taagccacat ctcgttaaat ttctttgttt
    12961 gaaggggttg tgtctcatat cgttctaaaa actccaaaca acgcctatac agccactcca
    13021 gcttatgata gtaggttcca actccaattc ctaaaatatc acaagtacga ctgactgaaa
    13081 cccttccaac aaccatctta gcgaacattg gaagaatggt gttcttttgt tggtgataag
    13141 tagtggtttc ttctcttttt ggtagaacat tagtgaactt cttacacgcc ttacattgat
    13201 agcgttgaga tttgccccta cttttccccc ttttgtaaaa ttgcttcggc tcattgaatg
    13261 gggttgattc ttcttccgag cagccttctt tatgaaattg ataatctggc tcaacatctt
    13321 ggatgctatt gatttctata aggcgtttaa tttcttcaac aacagaccaa ttagataaag
    13381 gggttactgt acagttttgc gatacacctc tgccaatagg attgtcattg cagtacatac
    13441 ctttatgacc tttatctttg gaactaccag tcattttata tcgacttggt ttccctttta
    13501 catctttgaa tttgtgctgt tctttcccaa aattacaaca aaacggattg atgcagtaat
    13561 tatattgaat gggatattca gaaccgttcc atttaaaaga cgttggcaag aacaacattt
    13621 tgttatacct tgttgcaaat cgttttggag ttaataaatc atattgttta gccctatctt
    13681 ttaattcttc gtttgaaatc ggaattttaa catctacaat ttcatcttcc ttcgtggcta
    13741 atcttttaag cttggtcatt gtctatcaac ccactctatc tttgataccc attttttcaa
    13801 caatccgctt attacttcgc ttgttggcaa tccattcaat aaacttctta tcgtctaaaa
    13861 tgttcaataa gaattcatcc actgcttcgc tttcagtacg ctctgcatat tcagcgtatt
    13921 gcttaactat cacccttact tgctctgata tttcccaatc cacagactta gcgttcttat
    13981 tttttggctc aagaaattgc ataggaaaat gcaccccttt ttgcttagta aattgtaacc
    14041 attttaacac accaatttgc attcctacaa taattatttc acgttcgcat ttttatatac
    14101 attttaactt acattttgtg gtgtaaatta acaacaaacg ttgatttaac aataaaaaac
    14161 gagtatcaaa ttcagttgca atttgatact catttaggtt tacattttca ctttttgtac
    14221 tccaaaactg aactacttaa atctatactg ctgcctcttt tttttagtac atgtccttca
    14281 tcttcgcagg aagtgccaat atgattttaa gaaaggtaat agacaaaaag tcaaaaagat
    14341 aaaacagagt ttcttcttta caaagggaat gtatgttcgt ataatggtat tgaggtgaag
    14401 gttatggaga aaaaatatgg aacagtagat aagatccgta ctttgcaagt tagtgccaga
    14461 ccgttgatcc gtttcagttt aaatggggtc aattgtttga ttgcttccca tagtttgaac
    14521 ttcctagctg aagtagacga agggatgaag ttagtcgtta caggttatta taataataga
    14581 aagcaatttg ttgtgagatc ctatcatgtg ttagggaaac ccaaaattgt ggtagaatat
    14641 gagaaaagtc tatacccaag aaaaaaggtc cgacaagatg aaagaataaa ctagaaaaca
    14701 agcggctgag acaaaaatgt cctagccgct tgttttggaa agatggatgc agacgatggg
    14761 atttgaaccc acacgagcat acgctcacaa gaacctcaat ctatatataa ctacatgtat
    14821 ttaagtattt gtgatgaatc actaaacttt ccaaactcat ttgagggata ttgcttaaag
    14881 attgaacaga tcaattcgaa gccctattag tattcgctca atggggggat cagaggccat
    14941 aaaaagagac tagtcattac tagtctcagg tagtggaatt gtaggatttt aaacgttcct
    15001 ggagagtacc ggtatgtaac tcgaagaggt gattatcata gtcgtaaaag taaattgaag
    15061 aagcctcgcc tttcacacga gaacgtcctg gttcgacagt taaacctaac atttggattt
    15121 ttgagacaaa cgaatctata tcttgttcgt caattttaaa agcaatatga ttgtatgtct
    15181 ttggcagttt attcgacgaa ttctgcatta ctgcaatcca taggtcctta actaagaaaa
    15241 atttttctgg atataatgaa aatttttttg ttgactatcg tagatttctt ttgcatcaaa
    15301 taaggtattt aacaattaag tatttaaaag ataactttta agttatcttt aagta
//
LOCUS       DACGEU010000065        15224 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.065, whole genome shotgun sequence.
ACCESSION   DACGEU010000065 DACGEU010000000
VERSION     DACGEU010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15224)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15224)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15224
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.065"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(74..604)
                     /locus_tag="IXR40_001957"
     CDS             complement(74..604)
                     /locus_tag="IXR40_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAQ4361794.1"
                     /translation="MRKVVLFIAMSLDGYIADGNGGVAWLNGHGNDNENIDTYTEFTK
                     DIDTVLMGWNTSHQVVTELSPQEWVYNKFTTYVLTHKECNSSQQIHFTSENPVLLLER
                     LKQEAGKDIWICGGANLVQQLVSKNMIDKYYISVIPTLLGNGVRLLGNIDREIKLRLC
                     KTQTYNGITDLIYMRR"
     gene            complement(786..1442)
                     /locus_tag="IXR40_001958"
     CDS             complement(786..1442)
                     /locus_tag="IXR40_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005603505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HAQ4361795.1"
                     /translation="MNKEWSELNKTMQAQIKKKDTYKRGIDTLLTLRSQLIQTLVSFK
                     EELCREDFNSIPFINADGYHSKTIAYSIWHIFRIEDIVVHTVINEDEQVFFAGNYQER
                     INSPIITTGNELMKQQIADFSKQLNLEELYLYIFEVWESTEKMLERLSYDELKRKIPK
                     ERKGYLESLNVVNDNEKAIWLIDYWCNKDICGLIQMPFSRHWIMHTEACLRIKNKIHS
                     "
     gene            complement(1569..2042)
                     /gene="dfrF"
                     /locus_tag="IXR40_001959"
     CDS             complement(1569..2042)
                     /gene="dfrF"
                     /locus_tag="IXR40_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrF"
                     /protein_id="HAQ4361796.1"
                     /translation="MIGLIVARSKNNVIGKNGNIPWKIKGEQKQFRELTTGNVVIMGR
                     KSYEEIGHPLPNRMNIVVSTTTEYQGDNLVSVKSLEDALLLAKGRDVYISGGYGLFKE
                     ALQIVDKMYITEVDLNIEDGDTFFPEFDINDFEVLIGETLGEEVKYTRTFYVRKK"
     gene            complement(2437..3828)
                     /gene="amt"
                     /locus_tag="IXR40_001960"
     CDS             complement(2437..3828)
                     /gene="amt"
                     /locus_tag="IXR40_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HAQ4361797.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGFLAMTISMVVSLYEYPTFATSGFSLVFFLLLGGLLWFIPVALCAAEMATV
                     KGWEKGVSQTKRY"
     gene            complement(4169..4411)
                     /locus_tag="IXR40_001961"
     CDS             complement(4169..4411)
                     /locus_tag="IXR40_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAQ4361798.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
     gene            complement(4443..5000)
                     /locus_tag="IXR40_001962"
     CDS             complement(4443..5000)
                     /locus_tag="IXR40_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAQ4361799.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            complement(5013..5201)
                     /locus_tag="IXR40_001963"
     CDS             complement(5013..5201)
                     /locus_tag="IXR40_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HAQ4361800.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            complement(5214..5780)
                     /gene="amaP"
                     /locus_tag="IXR40_001964"
     CDS             complement(5214..5780)
                     /gene="amaP"
                     /locus_tag="IXR40_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HAQ4361801.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
     gene            7010..7483
                     /locus_tag="IXR40_001965"
     CDS             7010..7483
                     /locus_tag="IXR40_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HAQ4361802.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            7492..7719
                     /locus_tag="IXR40_001966"
     CDS             7492..7719
                     /locus_tag="IXR40_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4361803.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
     gene            8355..8726
                     /locus_tag="IXR40_001967"
     CDS             8355..8726
                     /locus_tag="IXR40_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361804.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
     gene            complement(8982..9224)
                     /locus_tag="IXR40_001968"
     CDS             complement(8982..9224)
                     /locus_tag="IXR40_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAQ4361805.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(9256..10158)
                     /locus_tag="IXR40_001969"
     CDS             complement(9256..10158)
                     /locus_tag="IXR40_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAQ4361806.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            complement(10171..10359)
                     /locus_tag="IXR40_001970"
     CDS             complement(10171..10359)
                     /locus_tag="IXR40_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HAQ4361807.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            complement(10373..10936)
                     /gene="amaP"
                     /locus_tag="IXR40_001971"
     CDS             complement(10373..10936)
                     /gene="amaP"
                     /locus_tag="IXR40_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HAQ4361808.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            complement(10974..11867)
                     /locus_tag="IXR40_001972"
     CDS             complement(10974..11867)
                     /locus_tag="IXR40_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAQ4361809.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKDAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            complement(11945..12883)
                     /locus_tag="IXR40_001973"
     CDS             complement(11945..12883)
                     /locus_tag="IXR40_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HAQ4361810.1"
                     /translation="MRYYFVDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPD
                     DIFVGTEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLI
                     TCIDRKTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAAR
                     KTTENEELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQ
                     RQTEKMIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTG
                     GLPGKSSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            complement(12917..13267)
                     /locus_tag="IXR40_001974"
     CDS             complement(12917..13267)
                     /locus_tag="IXR40_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HAQ4361811.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            complement(13300..14202)
                     /locus_tag="IXR40_001975"
     CDS             complement(13300..14202)
                     /locus_tag="IXR40_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HAQ4361812.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            complement(14195..15052)
                     /locus_tag="IXR40_001976"
     CDS             complement(14195..15052)
                     /locus_tag="IXR40_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HAQ4361813.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
BASE COUNT         4393 a         3010 c         2396 g         5425 t
ORIGIN      
        1 aaatcttaag gattttcccg ccaacgtggt cggatcgctc cgtcggttta acagcttttc
       61 tgtttctctc tagttatcta cgcatataaa tcaaatcggt tattccgtta taagtctgtg
      121 ttttacaaag ccttaacttt atttccctgt ctatgttgcc caaaagacga accccatttc
      181 ctaacagagt aggaataaca gaaatgtaat atttatcaat catatttttg cttaccaact
      241 gctgaacaag atttgctccg ccacaaatcc aaatatcctt tcctgcttct tgttttagcc
      301 gttccaataa taaaacagga ttttcacttg taaaatgaat ttgttgggaa gaattgcact
      361 ctttatgtgt taatacataa gttgtaaatt tattatatac ccattcttgc ggagaaagtt
      421 cagtaacaac ctgatgagaa gtattccacc ccattaagac agtatctata tctttggtaa
      481 attctgtata agtgtcgatg ttttcattgt catttccatg accatttagc caagctactc
      541 caccattacc gtccgcaata tatccgtcaa ggctcatggc aataaataaa actacttttc
      601 tcattttttc tcttttataa atacaaacag gaatttattt ctctttttta ctcataaggg
      661 aacaactgat tgctacaaat aaacccatta aaatccatgg aaatgctgct cttataaaat
      721 cactaaccat actttattcc tccttaaatt ccaatttcct tagttctaca aactgaaatt
      781 tttgcctatg aatgtatctt gttctttata cgcaaacagg cttctgtgtg cataatccaa
      841 tgtcttgaaa acggcatttg aattagtcca caaatatctt tattacacca ataatcaatc
      901 agccaaattg ctttttcatt gtcgtttact acattcaacg attctaagta tccttttctt
      961 tctttcggta tttttctttt caattcatca taagataacc gttcaagcat tttctcagtg
     1021 ctttcccata cttcgaaaat atataaatat aattcttcca gattaagctg ttttgaaaag
     1081 tctgcaatct gctgtttcat gagttcattt cctgttgtaa tgataggtga attgatacgc
     1141 tcttgataat tgcctgcaaa aaatacttgt tcatcttcat ttatcactgt atgcacaact
     1201 atatcttcaa tgcggaaaat atgccaaata gaataagcaa tcgtcttact atgataacca
     1261 tcagcgttta tgaaggggat tgagttaaaa tcttctctgc ataattcttc tttgaaagat
     1321 actaaggttt gtattaactg acttcgtaaa gtaagtaaag tatcaatacc cctcttataa
     1381 gtatctttct tttttatttg tgcctgcatt gttttattaa gttcagacca ttccttattc
     1441 atattcaatc ctctctcaaa ttctgatttt atcgccccat acaaactgga atttgtctta
     1501 caacaattta tatatgcata aaaagcaata tatttatgaa aacaccctaa atccaaaatt
     1561 tactcaattc attttttcct tacataaaat gttctcgtat atttcacttc ctcaccaagt
     1621 gtttccccta tcaaaacttc aaaatcattg atatcaaatt ctggaaagaa tgtatctcca
     1681 tcttcaatat ttaaatctac ttctgtgata tacattttat ctactatttg caaagcttcc
     1741 ttaaatagtc catatccacc agatatgtat acatctcgtc ctttagccaa taataatgca
     1801 tcttctaatg atttaactga aactaaatta tctccttgat actctgttgt ggtggaaaca
     1861 acaatattca ttctattagg caacggatga ccgatttctt cataagactt tcgccccata
     1921 ataaccacat tacccgttgt taactctcta aattgctttt gttctccctt tattttccat
     1981 ggtatattac cattcttgcc tataacatta ttctttgacc tcgcaacaat caaacctatc
     2041 atctatttca tcctccataa tatgatgtcg tacctgtgat tccatcaagt gcaccacatc
     2101 ttaacaaact caaaattatc tcgaactaac cagctcgaca aattcctttt ttgtcttcat
     2161 ctgcattata tcatattgtt ataagcattg ccatttcttt tctgcttttg aaaagttact
     2221 tatcagccta tgttttgtaa agggtgatat tcagcatttc tcacgcaaca agcccttgac
     2281 aaaccataga ctaataagtt ttaaggtaat caagcagaaa tgaaatagtc tgctgtttca
     2341 cggcaacaaa aaagagatac caacacactt atgtagtatc tcttagtcta gtagcaatat
     2401 tcttttgttt gcaagcaggt aaacatgggc tgtttcttaa tatctttttg tttgggaaac
     2461 acctttttcc catcctttca ccgttgccat ctctgctgcg cacaatgcca cagggataaa
     2521 ccatagcaaa ccgcctaata acaagaaaaa tactaagctg aagcctgagg tcgcgaatgt
     2581 gggatattca tataatgaaa cgaccattga gatggtcata gccaaaaagc caaagaagaa
     2641 aaagtccaat ccttcttctt gttcttcttt tgtagtagtg atcgttgtaa agtgcatcgc
     2701 cgattttaaa atcactgttg tcagcacata ggcatacacg gcagtaatga tgacaccaat
     2761 cacttgaatc cctaagaagt accagctgct tggattcgtt agtaaatggc tgttagatgc
     2821 aaagatccct atcagaatcg tacctgtgaa tccgcccatg ccatgaacac cccacacatc
     2881 aagtgcatca tcccattgtt tctttttacg aaaatcaaca gcagcatgac agacgatacc
     2941 cgcaatgatc ccaatcagca tggcactttt tgcttctaca taaccggcac aaggcgtaat
     3001 ggctgccaat ccagcaacgg atcctgttag tacgtcgaca aaatcaaagc catttccttt
     3061 tacttttgca atgatcagcc aagtaatcat cgcaaatgca agagcgatga atgttgaacc
     3121 aaatgcattg actgcttgtt catctgctcg aagtgcacca ccggaattaa aaccgaacca
     3181 gccaaaccaa agcagtcctg taccgatagc agctgccata agactgctat gctgacttct
     3241 ttctcctaaa ggaatctttc tttgaccaag tgtgaggata catgctaaag agccgaatcc
     3301 agctgtcgtg tggatgactg ctccaccagc gaaatctcta aatcccatct gatccaaaaa
     3361 tccgccaccc catatccagt ggcaaacagg gaaataaatc agcagattcc aaaaaataac
     3421 aagtataata tagcctttta aattcaatct ccctgcaaaa gctcctgtca tcaaaggaac
     3481 ggtaatcacg ataaacatca gttggtaaag aaagaacatt aaaaatggaa tcgttgcacc
     3541 atgaaacatg ttggggaagc ttgtaacatg tctcatcaaa aagaaatctg ccgggtttcc
     3601 aataacaccg ccgatatccc gtccaaaggc caatccgaat ccaccaaata cccacataat
     3661 cgttgttatc ccaacggaga gaaaagattg agacatgatc gttagtatat tattcttccg
     3721 tgctaatccg ccgtaaaaaa aagctagacc aggagtcatc aggcaaacca ttgctgtaca
     3781 taaaatcatg aatgctgtat ctcctgtatt gataggtaat gtattcattt ttttcgcctc
     3841 ctttctacga ttacgagtat aaaagaaggt gtagttgttt ttttcttctg tttttttgaa
     3901 ttaatacttg catttataaa agacagacaa ttaataaaag cttgatgtgt tgtgctcttt
     3961 ttcgtttttc acacaaataa agacaaaaaa taaacggtct tctttttata gaaaaccgtt
     4021 tattttcgtc tttttttatt tttaaagata ttttttcata aggaataaag aatacttcat
     4081 ataaaatata taaaaaagaa ccgcagcgag tgtcgctacg gttctcaaat ttgttcttca
     4141 tttcaacata agtttttctt caatttgctt ataatttacg tgcaaagaat gaaacgacta
     4201 atactaaaat gattgcaccg atcaatgatg gaatgatagc cattcctgca attgttggtc
     4261 cccaagttcc tagtaaagct tgtccaattg ctgaacctac taaaccagca atgatgtttg
     4321 cgatgatccc cattgatgat cctttattcg tgattgctcc tgcaattgct ccaatgatac
     4381 cgccgacgat taatgcccaa ataaatccca ttttaaattc ctcctaactg acttcttact
     4441 tcttattgta cacgtggttc gttattttct ttgacttttt gtgcaccttt gcctacagca
     4501 gattttgctt tatctgtttg gcgtgaagca aattgtcctg tggattttgc tgcttctgtt
     4561 actttgtctt gtactgtttc ttgatctttt tggtattctt cttgtgtttt gatgtctgca
     4621 acattcacat tcacttcgat aacatctaaa tgtgtcatat tgtttacttc agtactgatc
     4681 aattctttga tttggttgta aatatcttcg atgtctttac cgtattctac gatcacatct
     4741 agatccacag ctacttgttt cttacctact tctgtattga tacctgctgt tacgttatct
     4801 gtgttgacta atttttcagc catatttgag aaaaatccgc catctaatgt caatagacca
     4861 tctacatctt tcaatgcata accgatgatt ttttggatga ctttgtcttc ataagtcaat
     4921 tcaccattca tcatgcggtt ttctcctttt tcatttgcca aaactgatcc atttgttgta
     4981 ttcatgtttt tgttttccat ctttgtttcc tcctatgatt taaaaaattg atcaactatt
     5041 cctgactgtt tcaaataaaa accgattcct gcgccaattg ctgtcatgat tatgatcaac
     5101 aatgtcttga aaaatccaat cgttaaccat aaaacagcta gcagtagtcc aagaccccca
     5161 aagataatag ggagcttgta tgctgaaaat agttctttca ttatttggcc ctcctattcc
     5221 actcgagagt gcttgtagtc tcttgtatct tcttgttctt cataaccgct gtatgtgact
     5281 gccactttga ccgtttcttt tgttccgagt actttagtta cttcttcttc gatatcttgc
     5341 atcaatacac ctgttttccc tactaatgaa gaagttcgtt tcaagtctcc gttgacatgg
     5401 atatggattc gatttttcgt tgaacgtatc cgtactttag gtgaatgaat gaactcttct
     5461 tcgtgtaaat gggaacgtac caacccttcg atcgcttttt tgtcgattgt tagtttgcca
     5521 tcttcccgtt tcataacgaa agttcctctt gactttggat agaaaagaac gactagcaag
     5581 atgataatag caagaacggc aaatactaca gctgcccaga aaatatattg ttgcatgtag
     5641 taattcgtta aagtaaagaa gcgaaatcgt tccaattgtt caggcataat atacggcgca
     5701 ttgatcaacg caatcgctag aaatactgaa agtagcagta aactcatgat aacaccgatt
     5761 atttttaacc ccttattcat tttccacctc ctataaactt atttttaccc tgtaaataac
     5821 tctaccgaca atcacagtat agatagcgaa cagttagcat agcatcagta aataaagcgc
     5881 taccaaacat tgctggatca taacggcgtt ttattgccag tctgatactg aaataacaat
     5941 tgcttactta ttctctattt acttttgatt gctggctata cttaaaggat attattcaag
     6001 attaaaaatt gcaaagatta tgctcagtta ttattacaag attctattta tttattaaat
     6061 tttttcggag aattaaaaaa tacaataaat aactttagtt actttaatgc gttcttactt
     6121 tatttttata ttatcatttt tcttattcac ttctttggtt tatactattc ttataaataa
     6181 aaatgaggta tgtcctatga tgaaaagatt gtactattca ttgatcataa cgattggcta
     6241 tttgattgta tcaaatctag gaaatatggt atttggtatc agtaaagaat tcagttggac
     6301 tactacatta tgggaatctc tattcttttt catcttcgta tttttgttac aaaattatcg
     6361 aaaaaaataa acatgtgcca tctatctgtt ggcacatgtt ttaggattta tggtactttt
     6421 tattcggcaa tccattttat ttttctactt cttcttaata cctctaacac ttttgattta
     6481 taaactaatc caatgcatct acttgcgctt attaagctat ttcagctaga tagtaccacc
     6541 ccatgcgtca atgcttgatt ttccttttgt ataacattgt ataagcaata aaggacaaat
     6601 aagtggtgat tacaccaaac cattgaataa gaaaaattct gatacgtaaa taaacatgaa
     6661 cttgaaaaaa ttaatgaatc ggttagctac tacgtagttg tcttttttct catacagttc
     6721 tgttaactta cacttctctt cgctagataa taaaaaatcc tccaactgta ttgtccaata
     6781 taatcccagg catctaaact agcattatag aagagacaca catagaatct aaaataactg
     6841 gttttaaatg tttcttacaa tcaaaaaaag ctgttaaatg cactccacac cttcatactc
     6901 tatcattttt tataaacgat atatttttat tgtttttcga taaaaaatag ttgttttaca
     6961 ataattattc tgctatattt tagctatcaa agataaaaga gggataaaaa tgaaatttaa
     7021 aacattgcta ttaaaatttg tcgttttagg tataagtgcc gtatttattt tgttcggcgt
     7081 acttttttat actcagatcg ctacaagcga aaaaggattc aattttgatt ggcagaccac
     7141 attatttgtt tctgtcattt actttgccct tctcctaggg atcgttattg cttatttctt
     7201 attgaaacta ttgaaaaaaa tcgaagataa ccaagctttt tccactcaaa gcttaaacat
     7261 actaaaaaaa atcgaacgaa ccattttgtt tattggtttc gccttttttg gcttacttcc
     7321 taaatttatg aaagtagcgg atttagacga tgctccaggt ttgatgttgg taggaatcgc
     7381 tgtcgtattc attccttttg cagtatacac attaacaagc gtgctggaaa aactgcttga
     7441 acatgcgatt ttacttaaga cagatcatga tttgacagtg tgaggtgcga catggcaatt
     7501 atcgttaatt tagatgtagt attagctcaa aaaaaaatga gtgtgactga attgagtgag
     7561 aaagtgggca ttacgatggc aaacatctct attctaaaaa atggaaaagc aaaagccatc
     7621 cgtttttcca ctctcgaaaa aatctgccaa gttttggagt gtcaaccagg tgatttgttg
     7681 acctataaaa atgactcgaa tactatacca gaagaataaa ataaagtaga acaaacagta
     7741 aataaaaaat aatctgaatg atagatgtgt gagactttta gaagttattt acgtctatta
     7801 ttcagatttt ttatttcgat tgaataccgt tttatctata aataagatat gtactgactc
     7861 atacaaaggg ggccttttct tctccatgta ctatcacttt tcctgataca actggtttcc
     7921 tgttacgttg tagttggatc tgcttttagt ataatacttt attcattcca ccagactgat
     7981 agcagtttga gcagtctaaa taatcatgta gtattacagg ccattctgtt tcataccttg
     8041 aagtgcttaa aacttcagct aatggcccat tgtgttaact cttactccat tcttttttag
     8101 taagctccca tatatactgt aaagccttct atatattatg tcatgttgct ttttaacatt
     8161 tactatgtag ttttgataaa atgatttgaa taacagtgat ggacaattct tttttatttt
     8221 taacattatt ttgataataa tgattattta tttaaaaata cattagataa catttgttac
     8281 gacacgaaaa agcttcacaa acaaatatcg ttattttaaa atgagggcga actcacacaa
     8341 ttaggaggaa tagtatgcca tttattgttt acttttttct ttcattactc gtgatctata
     8401 ttccattacc aacatttttc ctgctcgtca atcgtctagc agagcaacat gatacgattg
     8461 ctgctcttac gaaactttgt ttacttctat ttgtttgtct agattacttt acgagctatt
     8521 attggctaaa acagacaaga gtaaaaaaga gatattattt cttccttgtc tttttcaatc
     8581 tctttgagtt tctgatccat tgctttttac ttcatcagta tcatacgatc catttgtgga
     8641 tcatctgggt tttcaaagtg gtcgtattat tttgtatgtt cacctttcct atctcaagaa
     8701 aatttaggga ggcattgttt tattaaagaa gcttctctgt atcaataaag acacatttaa
     8761 ggaaaaactt ttaaaaatct aattgggaat ttgcccgcat aaataagagg ctgtgacaaa
     8821 agtcttgtca cagcctctta ttccgtataa acagtgttca aaagcttgca tcttcgataa
     8881 tatgcccaac caaatgaaaa atatgagaag ctatttttgt ttggctgttc ttattacttg
     8941 atgaagaaca gctttttcac gacctctttt taaaagtctt tttacagttt tcgagcaaag
     9001 aatgatacga ttagtactaa aatgatggca ccaatcaatg atggcacgat tgccattcct
     9061 gcaatacttg gtccccaaga acctaataat gcttgaccaa gtgctgatcc aactaaacct
     9121 gctacgacat ttgcaataat ccccatcgaa gaacctttat tcgtgattgc tcctgcaatt
     9181 gctccgataa ttcctccgac gataagtgac caaataaatc ccatgtttcg ttcctcctaa
     9241 tgttttactt ccttattact gaacccgtgg ttctgtattt tcttttactt tttgtgcgcc
     9301 gcttccagct gctgatttta ctttatctgt ttgattcgaa gcaaattcac cggttttttt
     9361 cgctgcgtca gttactttgt cttgcaccgt ttcttgatct ttttcaaatt cttcttttgt
     9421 tttgatgtcc actacgttag cgttgacttc gatcacttct aaatgtgtca tattttttac
     9481 ttctttgccg attacttctt gcatttcttc aaagattttt tcgatatctt tgccatattc
     9541 cacaatgaca tccatatcaa ctgctacttg ttttttaccg acttctgttt cgatcccagc
     9601 cgttacatta tctgtattca caagttttcc tgccacatta gagaagaaac caccgtttgc
     9661 agataataaa ccgtctactt gttcaattgc gattccgatg attttttgca caactttatc
     9721 ttcataattc agctcaccgc gcattgaatc ttcctgttca gaatcatgct ttccttggtt
     9781 atttgtatga tcagaaccaa gttttccttg tccgtttgtg tggtcagaac taagtttttc
     9841 ttgtgctttc gcatggtcag aaggatgttt ttgctcttcc acaggtttag aaggatcgat
     9901 tgcatcatgt tgttctggaa ctttagattc tggagttcct ggatgatgag gtgcatgctt
     9961 ttctgcatca tgtttcttct cttctactcc ttgttgaacg ttagggacta ctggatctgg
    10021 atgtgcagat actggtgctg ttttgttctt ttcatcgttc acaccatttg attggtttgg
    10081 tgtcgttggg tctggatgtg cagacactgg tttttggttg ttcattttat tgttattatt
    10141 tttgttattg ttattcatgg atgtttcctc ctaagattta aaatagtgat ctaagatttt
    10201 cgtttgtttc agataaaaac cgatagcgac gccgatcgct gccatgatca agatcaataa
    10261 ggtcttgaaa aagcccacgg tgatccataa aacggctaat atcaatccaa gtaccccaaa
    10321 gatgataggg agcttgtatg tcgaaaatag ttctttcatt tttggtcccc ccctattcta
    10381 ctcgtttgcg gtcattgctt cgtttagctg gttcttcaaa gcctgtgtat ttcaccgata
    10441 ctttcactgg ctcttttgtt cccaatatgt gttgtacttc attttcgatt tctttcatca
    10501 atgttcctgt tttaccaatg agtgctgaag ttcgtttcaa ctcccctttt acattgacgg
    10561 cgatcttgtt tttcgttgct ttgacattta cttttggtga atggatgaat tcatcttcat
    10621 gcaagtgaga acgaaccatt ccttcaattg cttttttatc caacgtcaac tccccatcac
    10681 catgtttcag tagaaagttt ccgattgttt ttggataaaa caggaaaaca agtaacgtga
    10741 taattgtcaa aatagcaaat gcaacggcaa gccaaaatac atattgttgc acgtatgaat
    10801 tagtgatgga aaagaatcga aacttctcta gctgaaaagg caatggatag gttgcactta
    10861 atagtatcgc aaacaaaagc acagatagca aaagtaatgt tccgatcact ccgatcgttt
    10921 ttacaccttt attcattttc gcacctcctc ataggggtga aacgatcaac ttcttataag
    10981 ttgatcgctt ctccaccagt tactccgtaa atttgggctg taacataact tgctttattc
    11041 gatgctaaga aaacataaac tggtgctaat tctcctggct gacctgcacg ttctagtaaa
    11101 ctttgctgac caaattcagg gatcgaatca gaaggttgtc cttcgtctag ttgtaatggt
    11161 gtccagattg gaccaggtgc tacaccattt acacggattc ctttaggtgc aagctgtttt
    11221 gctaaaccga tcgtaaagtt agcgattgaa gcttttgttg ctgcgtaatc taataaatgt
    11281 tcgcttggat tgaatgcttg aacagaagtt gttgttacga ttgctcctcc tgctgggata
    11341 tgcggaacag cttctttcac taaagcaaac atagcgatga tgtttatcat aaatgtgtct
    11401 ttgacttgct caagtggtaa ctcagcaata gactgacaag aaatttgctg tcctgcgttt
    11461 agtaccatcg tatctagccc gccaagttca ctcacggctt tatctatgat ttctttaggt
    11521 gcttgttcgt cacgaagatc aaaaggtagt aagacaatct tacgtcctgc atctttcacg
    11581 tattttgcta cttcctctgc atctttttct tctcctggga agaattgaag agcgatatct
    11641 gccccttctc tagcaaatgc aatcgctgct gcacgaccga tccctgaatc tccaccagtg
    11701 attagtacac ggcggttttc tagttgatta ttgccttcat aggattcttc tccacaatca
    11761 ggaacaggaa tcatattctg ctgtaaagct ggtgtatcct gatcttgttt aggaaatttc
    11821 tccgtatggt acaagtttcg cgggtcgatt aattttggtt ctgtcattgc tgtattcctc
    11881 ctagttttta aattgtattg ccaaaacaaa tttctttgtt tgatacctgt tttaaataga
    11941 ttctttaatt tgtataatct ttccggtata aatggtaacc taaaactact gctgctatca
    12001 aagagccaaa gactacgagt ataaagccta gagcagaact tttacccggt aatcctcctg
    12061 tattcattcc ccaaatccct gcgaacaacg ccggaacgga aatgattaat gcagctgaat
    12121 ctagatattt catgatatga tttagattat tgtccatcat cccgttgaat agatcaccaa
    12181 tactctctaa taaatctcga tagatctcga tcattttttc tgtttgtcgc tgtctcaaat
    12241 ggacatcata gagtagctgt tcatcgtcta aacgtttgat gaaagtttca gaattccata
    12301 attgatccat tgtttcccgt tgatctctta aggtatgatc gatatatacg atgtctcttt
    12361 caagatctgc ctgtttatac agttcttcat tttccgttgt tttacgagct gctttatcca
    12421 aagcgtcaat tcgctttttc atctctctta gttctttcac gtaatgggtg taaatatcta
    12481 ataatgtata cgtgatgatc ttttcaaacg agtttaaatg atttccatgc tttgtcagca
    12541 gccgatccac aaattcggtt tttctatcga tacaagtaat caagagatta tcggaaagta
    12601 caaaagatat tggcgttaat tttttttcga tacgattatc tgactgatct agattaatca
    12661 ctaccaaaga aaatggatgc tctagtttcg tctcataaag gcgctccatc cgagaaactt
    12721 cttccggata ttcggttcct acgaaaatat catcaggaag ctcgaattct tcgattgctt
    12781 gctcaatctc ttcgggcttt gcactatcaa gtacgagcca attatatttt ttttcatctg
    12841 tttctattac attcttttct tcatccacaa agtagtatct caatgtatac ctcctttttg
    12901 gactttctcg aaactattag ctgaagaagc agttctttaa tttgatatta taatcgagta
    12961 ctgcgatttc attttctaat gaaaagctgt caagctgttt gttgaagtcc atgttcaatc
    13021 gtttaccgaa ataattttgc tctaatttag atgtatagat gtccaataat ggatgctcga
    13081 ttttagtcgc atattctcca aattccgaaa caaaaggaat gatttgaaaa aagctgcctt
    13141 ttgcaaaagc acctttgtcc cttagaaatg gatcggaatc attgataagc gcgagtgcga
    13201 tttttgtatt ttccccaacc ttttcaatta acgtctctac tgcattttta gacattgtaa
    13261 tttccattcc tactccccct cttcagttgt ggtcttctat tatttaacaa ctacatctgt
    13321 ttttggttga acttttgcat attttggata tttagggaat ttagctacac aacggaaagc
    13381 cgtcatccct gcatattttt cgtaatattt cttcgttggc ccttcaaaat ccttgctcca
    13441 cggtttcaca tgtcctgaaa aatggataat gtaaggattg ttgcgagttt cttcgtattc
    13501 acgttcacct gctgctgttg gatgtttttt tgcttttgcc atgatatagc cttgtgcatt
    13561 ccaacgcgga tgaagtggta accaacggtc atgtaagata gcatttaatg catcttggtc
    13621 atggaatcgt aatttttctg gattatgttc gatgaaatct aatacttttt gcgtaatatt
    13681 ttcatctaac cattttttca cattgatcag catcaaacct gagttgaaat aacgcattga
    13741 tttagctgaa attttcattt tttccagtcg ttgatggaac ccagcgtctt caacagctgc
    13801 tacgattgaa tcaccgaagt caagacgcca taatttagag atatcttgta aagcgatcat
    13861 gtcgcaatcc atatataaga tacgttcaac ttctgtgccg cggaacaatt ccggaatcgc
    13921 aatacgataa taagctgttt ctggaatacg atcgctgatt accacatttg taaagaattc
    13981 tttattgatt ttcaagaatt ccacatctga gttcattcgt gcgtttttca ctgagaagcg
    14041 taaaagctgt ttactttcaa aatcgatatc atcgtcaatc acatagaacc gaacaaattt
    14101 agacgggttg caattatcta atactgagac aaataatgca gctaaatgtg gtacgaattt
    14161 tgtgttacaa cttgcgacta ctgctatttc ttttttattc attgatctcg cctactttcg
    14221 ttagagtact gtgtgctaat ttttttaagt ataaattggt atacggatga tctttcaacg
    14281 tattccaagg tttatcatgt cctgtaaagt gaacgatcga aggtttttca tttccttctt
    14341 tatactgacg ttcatatttt tcatttggtg ctggatgacg ttcaaaaatc agcgaagtct
    14401 gcatgttcca ttttggatga agttgttccc aatcttcata aagtacagca ttcaaagcat
    14461 cttggtcgtg atagatgatt cgatcgccat tttcactgag gtaatggata gttttttctg
    14521 taatttcttt tttattccat tgatcaatgt caatcaccat cactcctgaa ttgaagtaca
    14581 agtcatcgga atcgattcct aatctttcca aagctttcac ttggcctgga tcgataatag
    14641 cgccgattgt ttttccattt aacggctcat catatagttt tacgatatcg tctagtacta
    14701 acacatctga atctaagtaa aggactttct tataatcctc tttagctaat aagtttggta
    14761 aagaaattct taagtaagcg gtagttgtga tatggtcact gactaggaag tcttcgtaga
    14821 tatctttttc cactgtcagg aattggatac ttgcattact tgaatattta tttaccgttt
    14881 cttccaatcc ttctttacta tattctgata gaccatcgtc aatcacataa aattttatgc
    14941 gtcttgtttt attgcaattt tctaatgcag ttgcgatcat cacgctcaag taaggagcat
    15001 aattttcgtc tgaagcagtt accacaggaa ctacgccgta tctcttctcc atcaaaatca
    15061 ctcctttttc taatcttttt ctaacctgtt ctacatctag aatattcctc atttggtttt
    15121 aaagcaaaat atatgctttg ttttcattga atattttaaa atttttttat cacaaaacgc
    15181 atcggtaagc gctaactatt cgtttttcat ggctttttat tcaa
//
LOCUS       DACGEU010000066        14340 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.066, whole genome shotgun sequence.
ACCESSION   DACGEU010000066 DACGEU010000000
VERSION     DACGEU010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14340)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14340)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14340
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.066"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..266)
                     /locus_tag="IXR40_001977"
     CDS             complement(<1..266)
                     /locus_tag="IXR40_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4158 domain-containing protein"
                     /protein_id="HAQ4361814.1"
                     /translation="MDEIKSNKKAFGIYLGEPSTEQLNQFFYLHEKDLELMETIRRPA
                     TRLGFALQLVSLRFLGTFILDLTNIPQNVLSYVATQLNIDPGEI"
     gene            391..996
                     /locus_tag="IXR40_001978"
     CDS             391..996
                     /locus_tag="IXR40_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAQ4361815.1"
                     /translation="MGKIGYIRVSSQDQNLDRQLAMMEGLNIDKLFQEKASGKDTERP
                     EFQKLLNYIREGDCVIVTSLDRLGRDYEDIKNTVAFMKQKKVALKILDAQFLDFNTGN
                     ELLDTAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAQKAGRYKGRPIEYSINSTDPQ
                     KRLVFKTVVDMLKQGIPVAEIAKENGISRPTIYKIKKANDL"
     gene            complement(1062..1694)
                     /locus_tag="IXR40_001979"
                     /pseudo
     CDS             complement(1062..1694)
                     /locus_tag="IXR40_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002405587.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
     gene            1983..2375
                     /gene="merR"
                     /locus_tag="IXR40_001980"
     CDS             1983..2375
                     /gene="merR"
                     /locus_tag="IXR40_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hg(II)-responsive transcriptional regulator"
                     /protein_id="HAQ4361816.1"
                     /translation="MIYRISEFADKCGVNKETIRYYERKNLLQEPHRTEAGYRIYSYD
                     DVKRVGFIKRIQELGFSLSEIYKLLGVVDKDEVRCQDMFEFVSKKQKEVQKQIEDLKR
                     IETMLDDLKQRCPDEKQLHSCPIIETLT"
     gene            2404..4299
                     /gene="merA"
                     /locus_tag="IXR40_001981"
     CDS             2404..4299
                     /gene="merA"
                     /locus_tag="IXR40_001981"
                     /EC_number="1.16.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mercury(II) reductase"
                     /protein_id="HAQ4361817.1"
                     /translation="MNKFKVNISGMTCTGCEKHVESALEKMGAKNIESSYRRGEAVFE
                     LPDDIEVESAIKAIADANYHPGEAEEFQSEQKTNLLKKYRLNVEGMTCTGCEEHIAVA
                     LENAGAKGIEVDFRRGEALFELPYDVDIDIAKTAITDAQYQPGEAEEIQVQSEKRTDV
                     SLNDEGNYDYDYIIIGSGGAAFSSAIEAVTLNAKVAMIERGTVGGTCVNVGCVPSKTL
                     LRAGEINHLAKNNPFVGLHTSASNVDLAPLVKQKNDLVTEMRNEKYVNLIDDYGFELI
                     KGEAKFVNENTVEVNGNQITAKRFLIATGASSTAPNIPGLDEVDYLTSTSLLELKKVP
                     NRLTVIGSGYIGMELGQLFHNLGSEVTLIQRSERLLKEYDPEISEAITKALTEQGINL
                     VTGATYERVEQDGDIKKVHVEINGKKRIIEAEQLLIATGRKPNTESLNLHAAGVEVGS
                     RGEIVIDDYLKTTNSRIYSAGDVTLGPQFVYVAAYEGGLAARNAIGGLNQKVNLEVVP
                     GVTFTSPSIATVGLTEQQAKEKGYEVKTSVLPLDAVPRALVNRETTGVFKLVADAKTL
                     KVLGAHVVAENAGDVIYAATLAVKFGLTVGDLRETMAPYLTMAEGLKLAVLTFDKDVS
                     KLSCCAG"
     gene            4459..5781
                     /locus_tag="IXR40_001982"
     CDS             4459..5781
                     /locus_tag="IXR40_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAQ4361818.1"
                     /translation="MSDLLSLPDIKTIEPPQENETDMMFKVEAVGPPERCPECGFDKL
                     YKHSSRNQLIMDLPIRLKRVGLQLNRRRYKCRECGSTFWERLISVDEKRSMTKRLLKS
                     IQEQSMSKTFVEVAESVGVDEKTIRNVFKDYVALKEREYQFETPKWLGIDEIHIIRRP
                     RLVLTNIERRTIYDIKPNRNKETVIQRLSEISDRTYIEYVTMDMWKPYKDAVNPILPH
                     AKVVVDKFHVVRMANQALDNVRKSLKAHMSQKERRTLMRERFILLKRKHDLNERESFL
                     LDTWLGNLPALKEAYELKEEFYWIWDTPDPDEGHLRYSQWRHRCMSSNSKDAYKDLVR
                     AVDNWHVEIFNYFDKRLTNAYTESINSIIRQVERMGRGYSFDALRAKILFNEKLHKKR
                     KPRFNSSAFNKAMLYDTFNWYEVNDHDITDNFGVDFSTPIKNLEKGDL"
     gene            complement(5908..7413)
                     /locus_tag="IXR40_001983"
     CDS             complement(5908..7413)
                     /locus_tag="IXR40_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepS protein"
                     /protein_id="HAQ4361819.1"
                     /translation="MKVSDVISVILKSGIREYKCLNSKIKPIGYKAEGKKGAIFGFRS
                     KKLMTESRGIVLTSQEGLAENEDKFTHWTPNVYSYGAYADEKRIIVKGHNERNLQQIN
                     TFVIDFDRLTGEKLDSQMILDAAIDLELMPTLILETPGGFQAYFILENAWYISSKNNY
                     QSIEVAKRVSENLRKAFAEELPSVDLGCNHFGIARIPRTDNIVYYYPALTHDIQQLIQ
                     WSMKYEPAKTYKKPLLSLVKNKYKQVNEMWYRQLISNPKIVGAKGIMGRNNVIFTLSL
                     ANYASGVDLEDCLNEMDLFNSSLERPLKDRERVRIVKSAYSGKYRGASKTYVQELVSN
                     WGLESLSEEKMFTQQRNTWYKFKKERHKRKKSHLSEWKEDILAYLETQCYRYRPEVRL
                     KKTDLQAAITFNGQSIPKRSLDRALKELMAEGKLFVQIKAGRNGGLVVATRKALIRTV
                     IQVKQQVKSAYKQGIKTFFKEADMLVRIFREPDKYSQRVDHYKQLNLWNTG"
     gene            8117..9007
                     /locus_tag="IXR40_001984"
     CDS             8117..9007
                     /locus_tag="IXR40_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAQ4361820.1"
                     /translation="MANTIIFGQQKGGVGKTTDTCMITLVAAMLMKKRTILIDIDLQA
                     NATNFMTKTFGVETVPQTLMSALENGDLRPAIVNLKENLDLIPAGYDMRLYTEFLTEN
                     FDNTIDRTFYLKNLIEEIKDDYDYIFIDIPPSTDLKVDNAMVACDYLVVVQETQQFSF
                     EGSQRLIFDYIQTLVDDFGSDVPIQIAGILPALLQQKRPMHQKLVEETIDTFGRDNVF
                     NTIIQNHARLEWYPRIGFQFQDYHDKKMIALFADIFCELEERITLYKSNGDIQDYFYT
                     PRYILDGKLTSLGKEISLNV"
     gene            9000..9284
                     /locus_tag="IXR40_001985"
     CDS             9000..9284
                     /locus_tag="IXR40_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002412979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361821.1"
                     /translation="MSSLINRKIPQGATANKEADTKRKVTIQKKSSKKILASERKNIK
                     VSPSTFDLIKTISTMKSYKNYEFIDKAVESYIQNNLTEREQRILKNLISK"
     gene            complement(9317..9556)
                     /locus_tag="IXR40_001986"
     CDS             complement(9317..9556)
                     /locus_tag="IXR40_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010621028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361822.1"
                     /translation="MEQSDNVPLDRHKCKEHVFKDKRFVEKESESLTLLGYKIVVDTV
                     TGVNYLETPKGGITPLLDKNGKICIDKKKSINKKG"
     gene            complement(9952..10149)
                     /locus_tag="IXR40_001987"
     CDS             complement(9952..10149)
                     /locus_tag="IXR40_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002412976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAQ4361823.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKNYFYCP
                     KCHRRYKQKQGEYVAITIIKE"
     gene            complement(10183..10482)
                     /locus_tag="IXR40_001988"
     CDS             complement(10183..10482)
                     /locus_tag="IXR40_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361824.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
     gene            complement(10523..11140)
                     /locus_tag="IXR40_001989"
     CDS             complement(10523..11140)
                     /locus_tag="IXR40_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAQ4361825.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            complement(11465..11860)
                     /locus_tag="IXR40_001990"
     CDS             complement(11465..11860)
                     /locus_tag="IXR40_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361826.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
     gene            complement(11940..14291)
                     /locus_tag="IXR40_001991"
     CDS             complement(11940..14291)
                     /locus_tag="IXR40_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1906 domain-containing protein"
                     /protein_id="HAQ4361827.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
BASE COUNT         4720 a         2565 c         2303 g         4752 t
ORIGIN      
        1 ataatttctc caggatcaat atttagttga gttgctacat aactcaatac attttgggga
       61 atattggtaa gatctaatat aaaagttcct aaaaaacgta gtgagactaa ctgtagtgca
      121 aaacctaatc tagtagctgg tcgtcgtata gtctccatca attctaaatc tttttcatgc
      181 aaataaaaaa attggtttaa ttgttctgta ctaggttctc ctaaataaat gccaaatgct
      241 tttttgttac ttttgatttc atccatttaa accctccatg aagtaaattt taagtctaca
      301 taaaatttat ttttaaaaat gctatgatag cagtaaaact acaagtaaat tttacatgta
      361 aattatatca cttttaaaaa ggagtttttt atgggaaaaa ttggctatat tcgagtatct
      421 tcacaagatc aaaatttgga tcgacaattg gcaatgatgg aaggacttaa cattgataaa
      481 ttattccaag aaaaagccag tggtaaagat actgagcgtc ctgagtttca aaaattacta
      541 aattatatcc gtgaaggtga ttgcgtcatc gttacatcac tagatcgttt aggaagagat
      601 tatgaagata taaaaaatac agttgctttt atgaaacaga aaaaagtagc gttaaaaata
      661 ttagatgcac agtttttaga ttttaatact ggaaatgaac tcctggatac cgctatgttc
      721 gatatgtttt tatcactgct aagttatatt gcacaaaacg agcgtgagaa aattcgtgaa
      781 cgtcagcggc aaggagtatt attggctcaa aaagccggcc gatataaggg acgaccaatc
      841 gagtattcta ttaactcaac agatccgcaa aaacgcttag tttttaaaac cgtggtggac
      901 atgttaaagc aaggcattcc agttgcagag attgcaaaag aaaacgggat ctctcgacca
      961 actatttata aaataaagaa agcgaatgat ttgtagaaat atactacatt cattcgcttt
     1021 tctaccgcac tatttcgttt ctatgttcca tgtaccccga tatagggtcc attataaatc
     1081 acactatcag agttcgtacc atatctatct ccttcttttt caacaacttc ctgtttttga
     1141 ggaaaaaatg ctgtattaat tagcatagaa gtgaaatatg ggattggcgt actcaaatta
     1201 ataaccaaag tattcttatc cttagcataa actcccaact tatctggttt catagttcct
     1261 gagattattt ctttaccatt tttaatagat tcaaaaaaac caatatttgg tgaatcttga
     1321 ttacttaacg ttcttttcca cgaataaaca tagtcatctg caacaacagg cgtaccatta
     1381 ctccacattg catcctttct caatcgaata acgtacttaa gtccatcctt agagatttct
     1441 ggaaggccat tagctcctcc aggtacaatt tcacctttag cattaagttt atataatcct
     1501 tccattacgt tatttaaaac aagttggctt gtagggtcga tagctaactt cggatctaag
     1561 ctttgtactg tagtagaaac agcaaaagta taagctttgg tttcttttgc tgtttcttga
     1621 gacttttccc cacaaccagt aataattatt cctaacataa gaattgttaa attctttccc
     1681 caagttcttt tcaaaaaaac acccctattc aatttcttat ctgattgttc tagcaacact
     1741 tagcttaatt atactgtaaa aaaaacgggt cttcggaata tatagtggaa ttactttctt
     1801 aatagtttaa aaacaactgg tgtttaaatc ggattttctg gtgggatgtt aggataatca
     1861 atagtattat ataaaagtat caatcacata cgagtgatac tttgggaaaa aaataaaata
     1921 gtccaattta cttgaacgtg tactatggta cacggtttat aatattcatg gggtgaaata
     1981 agatgattta tcgcattagt gagtttgcag ataaatgtgg agttaataaa gaaacgatca
     2041 gatattacga gcgaaaaaat ttattacaag aacctcaccg aacggaagct ggttatcgga
     2101 tatattcata tgatgacgtt aagcgtgttg ggtttattaa acgaatacag gaacttggtt
     2161 tttctttaag cgagatttat aaattacttg gtgttgtaga taaagatgaa gttcgttgtc
     2221 aagatatgtt cgaatttgtt tctaaaaaac aaaaggaagt gcaaaaacaa atagaggatt
     2281 taaaacgaat tgaaactatg ttagacgact taaaacaacg atgtccagat gaaaagcaat
     2341 tacattcgtg tccaataata gaaacattaa catgagagat taattaacga aaggagcttt
     2401 tttatgaata aatttaaggt aaacatttca ggaatgactt gtacgggttg tgaaaaacac
     2461 gtagaatcag cacttgaaaa gatgggtgct aaaaatattg agtctagtta tcgtcgtggt
     2521 gaagcagtat ttgaactgcc cgatgatatt gaggttgaaa gtgcaataaa ggcgattgct
     2581 gacgcaaact atcacccggg cgaagcagaa gaatttcaat cggaacaaaa gacgaattta
     2641 ttgaaaaaat atcggctaaa cgttgaagga atgacctgca ctggttgtga agaacatatt
     2701 gcggttgctc ttgaaaatgc aggtgcaaaa gggattgaag tagactttcg tcgcggagaa
     2761 gcactgtttg aactaccgta tgatgtagac attgatatcg cgaaaacagc gattactgac
     2821 gcacaatatc aaccgggcga agcagaagaa atacaagtgc aatcggaaaa aaggacagat
     2881 gtaagtttaa atgatgaagg taactatgat tatgattaca tcatcatcgg ttctggtgga
     2941 gctgcctttt catctgccat tgaagccgtt actttgaacg caaaagtggc tatgattgag
     3001 cgtggaacgg tgggtggaac ttgcgttaat gtcggatgcg ttccttctaa gaccttatta
     3061 agagcagggg aaatcaatca tctagcaaaa aataatccat ttgtgggatt acacacttcg
     3121 gcttcaaatg ttgatttagc gccattagta aaacaaaaga atgatttagt aaccgagatg
     3181 cgaaatgaaa aatatgtgaa tttaattgat gattatggtt ttgaattaat aaaaggtgaa
     3241 gcaaaattcg taaatgaaaa tacagttgaa gtaaatggca atcaaatcac agccaaaaga
     3301 tttttaatag ctacaggtgc ttcttcaact gcacctaata ttcccggatt agatgaagta
     3361 gattatttaa caagcactag cttattggaa ttaaagaagg ttccaaatcg tcttaccgta
     3421 attggttcag gatatatcgg catggaatta ggacaactat ttcataacct cgggtcagaa
     3481 gtcactttga ttcaaagaag cgagcgtcta ttaaaagaat acgatcctga aatttcagaa
     3541 gccattacta aggccttaac agaacaggga attaatttag taacaggtgc aacctatgaa
     3601 cgagttgagc aagatggaga cattaaaaaa gttcatgttg agataaatgg taaaaagcga
     3661 attattgaag cagaacaatt gctaattgcc actggaagaa aaccaaatac agaatcatta
     3721 aacttacatg cagcaggcgt tgaagttggt tcccgtggtg aaattgtcat tgatgattat
     3781 cttaaaacga ccaattcccg aatttattca gctggagatg tcactctcgg tccccaattt
     3841 gtttatgtag ctgcttatga aggtggactt gctgctcgta atgcaatcgg aggactaaat
     3901 caaaaggtca atttagaagt ggttccaggc gttacgttta cttctccatc gattgcaacg
     3961 gttggtttaa cggagcaaca ggcaaaagaa aaaggatatg aagtgaaaac atcggtattg
     4021 ccgttggatg ctgttccaag agcgctcgtt aatcgggaaa caacaggtgt tttcaaatta
     4081 gtggcagacg cgaaaacatt gaaagtgtta ggggcgcatg tagtggcaga aaacgcagga
     4141 gacgtaattt atgcagcaac attagctgtg aaattcggtt taactgttgg agatctgaga
     4201 gaaacgatgg ctccatatct aacaatggca gaaggattga agctggctgt cctaactttt
     4261 gataaagatg tttcgaaatt atcttgctgt gcaggctaag ggaacttttt tacaactccc
     4321 tattcaagtg aaccagctaa tgctttaagg gattttctaa gtgcatttgt ggtcacaaaa
     4381 ataatttaac actgatgatt tcgacatcaa atctataatt gataccttaa caccgcagag
     4441 taataaagga tgaataatat gtcagactta ttatccctac cagacattaa aacaatagag
     4501 ccgccacaag aaaatgaaac cgatatgatg tttaaagttg aagcagtcgg accacctgaa
     4561 cgttgtcctg aatgtggttt tgacaagttg tacaaacaca gttcaagaaa tcaactaatt
     4621 atggatttgc ccattcgttt aaagcgagtg ggcttacaat tgaaccgtag acgatacaag
     4681 tgtcgtgaat gcggatctac cttctgggaa cgcctaatat ctgtagatga gaagcgtagt
     4741 atgaccaaaa ggcttttaaa gtccattcaa gagcaatcca tgtctaagac ctttgtagaa
     4801 gtcgcagaaa gcgttggtgt tgacgagaaa accattagga acgtttttaa ggactatgtg
     4861 gcactcaaag aacgtgaata ccagtttgaa actcctaagt ggcttgggat agacgagata
     4921 catattatcc gtagacctcg gcttgtattg actaatattg aacgcaggac tatttatgac
     4981 atcaagccta accgtaacaa ggaaacagtc atccaacgtc tttcagaaat cagtgacagg
     5041 acttacattg agtacgtcac aatggatatg tggaagccct acaaagacgc agtgaaccct
     5101 atccttccac acgctaaagt tgtcgtagat aagtttcatg tagttagaat ggctaatcaa
     5161 gccttagata acgtcaggaa gtctttgaaa gcccatatga gccaaaaaga aagacgtacc
     5221 cttatgcgtg aaaggtttat ccttctaaag cgtaaacacg atttaaatga acgtgaatca
     5281 ttcctcttag atacttggtt aggtaatctt cctgctttaa aagaagccta tgaactcaaa
     5341 gaagagtttt actggatatg ggatactcct gatccagatg aaggtcatct tcgttatagt
     5401 caatggagac accgttgtat gtccagcaac tctaaagacg catataaaga cctcgtgaga
     5461 gccgtagaca actggcatgt cgaaatattc aactactttg ataaaaggct cactaatgct
     5521 tatacggagt caattaacag cattattagg caggtagagc gaatgggtag aggttactcg
     5581 tttgatgcct tacgagccaa aatccttttc aatgagaagc tccataaaaa gcgtaagcca
     5641 cgatttaatt caagtgcttt caataaagct atgttatacg atactttcaa ttggtatgaa
     5701 gtgaatgatc acgacattac agacaacttt ggtgtcgatt tttccacacc tattaagaat
     5761 ttggagaagg gtgatttata agcccttttc caccataaaa tccgaatacc caaaaaaaca
     5821 aaaatataca gaattaggat aataactaac aaaaacgaaa acaagtataa aagaaatata
     5881 atgtataggc acttgacatg ttttatttta tcctgtattc cacaaattta attgcttata
     5941 atgatctact ctttgactgt atttatccgg ttctctgaag attcttacta acatatcggc
     6001 ttctttaaaa aatgtcttaa tgccctgttt gtacgcagat tttacctgtt gcttcacttg
     6061 aatgaccgta cgaattaacg ctttacgagt ggcaactact agtcccccat tccgtccagc
     6121 ttttatttgt acaaataatt taccttcggc catcaattct tttaatgcac ggtcaagaga
     6181 acgtttagga attgattgtc cgttgaaagt aatcgctgct tgcaaatctg ttttcttcag
     6241 tctgacttca ggtctgtatc tataacattg ggtttcaagg taagctaaaa tatcttcttt
     6301 ccattcggaa aggtgagatt tctttctttt atgacgttcc ttcttaaatt tgtaccaagt
     6361 atttctttgt tgtgtaaaca ttttttcctc agacagcgat tctaagcccc aatttgacac
     6421 taactcctgt acataagtct tacttgcacc tctatacttc ccagagtaag cactttttac
     6481 aattcttact cgttctctat cttttagagg acgttctaaa gaactgttaa aaagatccat
     6541 ctcatttaga cagtcttcta agtcaactcc tgatgcataa ttggccaaag ataaagtgaa
     6601 aatcacatta ttccggccca taatcccttt agcgcctaca atttttggat tactaattaa
     6661 ttgtcgatac cacatttcgt tcacttgttt atatttattt ttaacaagtg aaagtagcgg
     6721 ttttttatat gttttcgctg gctcatattt cattgaccat tggattaatt gctgtatatc
     6781 atgtgttaaa gctggataat aatagacaat gttgtcagtt ctagggatac gtgctatccc
     6841 aaaatgattg caacctaaat cgactgaagg caattcttca gcaaatgctt ttcttaagtt
     6901 ctcagatact cgtttggcca cttcgattga ctgataatta tttttggacg aaatatacca
     6961 ggcattttca agaataaagt atgcttggaa gccccctggt gtttccaaaa taagggttgg
     7021 cattaattcc agatcgattg ctgcatcgag aatcatttga gaatctaatt tttcgcctgt
     7081 taagcgatca aaatcgatta caaaagtatt gatttgttgc aagttgcgtt cgttgtgccc
     7141 ttttacaatt attctttttt catctgcata tgcaccatag ctgtaaacgt taggtgtcca
     7201 atgagtaaat ttatcttcat tttcagctaa gccttcttga gaagtaagaa cgattccacg
     7261 agattccgtc attaacttct tggatctaaa cccaaaaata gcaccttttt ttccttcagc
     7321 tttatagccg attggtttaa ttttgctgtt taaacacttg tattcacgaa taccactttt
     7381 taaaataact gaaatcacgt cagaaacttt catcttatca ccacccattc tatatttaaa
     7441 aaaaggagaa ctgcaggcat tctacagctc tcctttaaac cttatttgca gctaaaatat
     7501 agctcaaaat cttgattttt aaggtcccaa atgatataat taaaaagact aagagagctg
     7561 caactctctg taatctaaaa ctataatggg acgaaagaga atcatgaaat gctgtgtaca
     7621 ttttgattct gtaatttagt tgatcggcaa atcaactaag ttaccgtctc tatttttttg
     7681 tctataattc aattagtaaa tgtatctttt ttctattcat tcaaattctt ctttagaata
     7741 catgtcacta caacttttgt aaagtaaaaa ttttctctca aataatcatt cttaatttat
     7801 ttttgtatcc ttttatcttt gtatcctttt atctttttat ctttttatct ttttatcctt
     7861 taattttatt gttgtatctt tttatctttg tatcctttta tctttttatc tttgtatcct
     7921 tatttagaag tctatttaat aacttttctt ataaaatgct atctgattaa ataagtatgt
     7981 tttaagataa ttagaaaaaa gatacattta tctatttaca attaattcta tttgtattac
     8041 tatttaaata tagaaaaaag atacaaagat acatttatct tttattacat tttgattaca
     8101 aggaaggagt atattgatgg ctaatacaat tatatttgga caacaaaagg gcggggtagg
     8161 aaaaacaact gacacttgca tgataacgtt ggtagctgcg atgctaatga aaaagcgtac
     8221 tattttaatt gatattgatt tgcaagcaaa tgcaacaaat tttatgacaa aaacatttgg
     8281 ggtagaaacg gtacctcaga ctttgatgtc tgctcttgaa aatggcgatc tacgtcctgc
     8341 tatcgtaaac cttaaggaaa acttagattt aattcccgct ggttatgata tgcgtctata
     8401 cactgaattc ttaacagaaa attttgataa tacaatagat agaacttttt atcttaaaaa
     8461 ccttattgaa gaaattaaag acgattatga ttatattttt attgacatcc caccttcaac
     8521 cgatttaaag gtagataatg ctatggttgc atgtgattac ttggttgtag tacaagaaac
     8581 acaacaattt tcttttgagg gaagtcaacg gctaattttt gattatatac aaaccttagt
     8641 tgacgatttt ggctcagacg ttccaattca aattgcaggc attttacctg cattgttaca
     8701 acaaaaacgc ccaatgcacc aaaaattagt tgaggaaaca atagacacat ttggaagaga
     8761 caatgttttt aacactatta ttcaaaatca tgcacgttta gagtggtatc cacggattgg
     8821 atttcaattt caagactatc atgataaaaa aatgattgct ctttttgcag atattttctg
     8881 tgaattagaa gaacgcatca ctctttataa aagtaatggt gatattcaag attattttta
     8941 tactccgaga tatatattag acggaaaatt aacttccctg ggaaaggaga ttagtctaaa
     9001 tgtctagttt gataaatcgt aaaatcccac aaggggcaac agcaaataaa gaagcagata
     9061 caaaacgaaa agttactatt caaaaaaaat cgagtaaaaa gatattagct tcagaaagaa
     9121 aaaacatcaa agtgtccccc tctacttttg acttaattaa aaccatatca acaatgaaaa
     9181 gctacaaaaa ttatgaattt attgataaag ctgtagaaag ctatatacaa aataatttaa
     9241 cagaacgtga acaacgtatc ctcaaaaatt taatctcaaa ataaataaaa aaggataaaa
     9301 agatacatgt atctttttat ccttttttat ttattgattt ctttttatca atgcagattt
     9361 taccattttt atcaagtaga ggcgtaattc ctcctttagg agtttctaaa taattcacac
     9421 cagtaacagt atcaactaca attttatagc ctaatagagt taaagattca ctttcttttt
     9481 caacaaaacg tttgtcttta aatacatgtt ccttacattt atgtctgtct aatggtacgt
     9541 tatctgattg ttctatcaac tcactatttg aattatcccc ggcaaccatc atgcctaaat
     9601 ttttatcata ataaatatat tctccaccta gtattaaggt taatggcata aaaatcttcc
     9661 tttctttaat tttcttaccg tcctttttct ctttttttaa cggctttcgt tacttacctt
     9721 tttgttcatt ttctacgcac aatcaatcga ttaaacagat tgcctcttat tccaataagt
     9781 aaatttcaag tgcaaatcat cctattttta aataggatct gttgtcaact ttttcttaat
     9841 tctatcaaaa aacggaagat tttgcttgca aaccaattcc cttttactaa attaaaatag
     9901 gtttttattt agtatgaaac agaaaccaac attgaagtaa atcttatttg tttattcttt
     9961 aattattgta attgctacat attctccttg tttctgtttg tatcggcgat ggcatttagg
    10021 acagtaaaag taattttttt gataaacact ttttgctaat tccccacagt cacactccac
    10081 gtgaaaagca atatttcgat taaaactagt tatttcaatg ccccaacgat cataagattt
    10141 tcgcttcata aaaattttcc tccttgtaaa ttttactaac gattataaat accgttgcca
    10201 ttctttcaac tgttgactaa ttaacgcata aaattcgact tctgataaaa tggtaatctc
    10261 atgacctaac gcaatcaagt cccgcgcggt ttgttccttt tttgtataga gagaatcatc
    10321 aaacaacgac ttagaatact gaccacaaac caggaaattt gtttttgaag taacacttga
    10381 ttgacaatgg ccgtttaaag agtgaaccaa accgatggct tgggttcgtg tcatttgctg
    10441 cagcgttcca gtaaaaacga ccctttgatt cgttaagtcc attttcaaac tctcccttcc
    10501 cgtctaatag ctgttatatc tatcaagaaa agtggtgcaa ggtatgttca tattctttca
    10561 cccgtcgata aaaggtattt cgtttcatgc ccaattgatc catagcatag actgcagtta
    10621 tctttcctgc tttccagtca gaatagatcg caggaaattc aggaggtaaa gcaattttct
    10681 ttctgccgaa ttttacaccc ttttgtttcg cagcttctac gccttctctt tgccggctat
    10741 taattcgttt ccgctcgtct tcggccatat agctgagtaa ttgcagaatt aagtcagaga
    10801 taagcgtctc taacccatct agttgcttgt aactagcagt atctaacaga ggcatgtcta
    10861 acacagaaat atcaatctgc ttttccttag ttaattctcg ccattcttct aaaatcattt
    10921 gtttatttct gcctagtcta tctaatgatt gtagatagag taaatctcct tttcgaaaca
    10981 tccgtttcat taattgatat tcagggcgtt taaaatcttt gccgctggct ttttctacaa
    11041 atatatattc ttcagggatt cctaattcct tcgcggaaat cagttgtcgt tcgatcgatt
    11101 gatcataact actgacccgg atataaaaaa attttctcat cgtttttatc tacccttttt
    11161 tcactaaaat tgtttcaaaa caatcagatt aaatcagaaa cgtttcaaat tgtattatgt
    11221 ggttattatg ccatacataa acaaagaaaa tcaaggcatg tcaaaaagta tactttttga
    11281 aacagtaagt ttacactccc gcatgattat atttattccg ctaaaataca taaaaatggc
    11341 aggccttaac ggtctgccat taaataaact agttatccag tttttctttt atgtcttcca
    11401 tggtatattt tatttttcac atcagaattt gacttcttta acttttacaa tttttttaac
    11461 actattattc tattacaaca ctatatattt ctaatttagg gttaaaaata aatctttttg
    11521 atacttttgc ctttacaata taattgtatt ctttcttttt ttctttgaag tcgcttgatt
    11581 caactgtaac ttcaaaccac atttcatttg gagactcttt taattttttt acttgaaatg
    11641 aattatctct tggatcataa ggtggtactc tttcaaactc aggaagtttt ctctgtattt
    11701 gttcttcagg agtattcgca aagtaatcta ctatcttgac agttattaaa agtactacta
    11761 ttcccaaaac tataacaaac ataaagataa ttccacatcc agaattattt ttattatttt
    11821 gagtcagatt attccattct atttcttcca taatcatcat gtccttttac aattcatata
    11881 cttattttat cgtatatatt taaaaaggaa aaggacactg tttaaatagt aaacgattct
    11941 taattaagtt tacttctatt ttcttgaaat tgaataattt tttcagaaaa tccatttgca
    12001 actttcccct catctccaat aaaatcaaga taagtaaaat ctgtcccaag tgaattatta
    12061 actattttat caatgaaaaa tgaaattatc cctacaccta agatatcaac tgtttcgtca
    12121 ttttctaata aactatttgt tactgaagcg attttatctg aagaaccaaa tctgttctta
    12181 acaaattgat taaatctatc aatagcaccc ttatcacaat agtacgtttt taaagccgat
    12241 aaagctgttg aatcagaatt tctttttgct aaggtataaa catttaccgc gtcaacatct
    12301 tggtataaat cttctagact aaatgttcca cctgcagccg tacctactaa tgcaaataca
    12361 ccttgctcca tttgtattcc taatttctta acttcacccc agcaagtcat taaatctcct
    12421 aaccaacctg caaagtcaga aacactatca ttgattgtgt cggctagaaa catctgtgat
    12481 tgtaacgtca caattaagtg aggcaaacct attattgaac cagtattagg atctataaaa
    12541 taattataca ggccctcgct attagttaat ttattcctat attcatcata aatttttcta
    12601 tcatgctctg ttacaggaga agaaatgatg tcccatgaca aaccagaata atttacatat
    12661 ctataaaatg tcaaatgagg gttccaagga ttatcaagac cagcttgtga tagatattga
    12721 tacgcacgta ccatctgatt tataaccttc tgattgtatt tggcaatgta attatcatta
    12781 ttagtatcat ttgataactc attaaatccg ctatctctac ccgatgtagc gattaaatcg
    12841 ataccaacag ctccgttgcc acttcctatg gtaaattcaa caaattgatc aaaagaccat
    12901 tgtctaggca taggaaaacc taaattccca ctataaccag tcgacatatc tgaaacaaat
    12961 gcaaacgaag catacccgtt attgattatt tgagaacaaa catttcttgt tccgtaaaca
    13021 cccgtttgat acccgctata tgacattaca gcagataccc ccttaaaata ttctccagca
    13081 tatgcaagaa tttcttcccc taacatgtct agatcaacag caaaataaat aactgttgtt
    13141 aatggtatat ttagattttt tgctgcatct atagccttct taccatctga taagccacga
    13201 tcataagtaa aataagctaa tgctgcacct ccatcttgat agataggaaa cacagataaa
    13261 tttttagaaa aaatattatt caattcctct gtagttagat acttatttcg ttcatctttt
    13321 ccaattccaa cagtaccagt aagatatcta ccaactattt ttatatcatt atcaaccaat
    13381 gtttggattt gagatctagt taattgcgta gaagtatctg cgccatctgc agatcttcta
    13441 atatctccag cgctagacaa tagtcctttt attacaacaa catctgctat ttcagtatat
    13501 tcaggcaata ccataaattt tcggaatgcc agtacttcta aacccatata tttagtgaaa
    13561 ataccatcga atgtaccgtc ttcaaaataa ccattaacat ataatccata ttgaattatt
    13621 cttacatagt ttcccgagtt accttcagac acaggataag ttttactagt tgtcccatta
    13681 ccataagacc ctgttgcttc actgggagaa tatcctagtt cagcttgtaa tgcaaaaatt
    13741 aatgcttgat ttgaatttct ttgataaata ccatcacaag gcattattcc cgtgtattct
    13801 aaataattta catttaacca ttgctgcatt tttctaattt tactatctcc gccgggaaca
    13861 agaacaaaag cactcatatc aaataacgct ttggcccatt tcgcatccaa aactccagtt
    13921 acagcgcttc cattaaaccc tgcatcagtc tgcaactctt ttacagcagt atctaaatat
    13981 ggagtatata ccccatcgaa gccacctgga ttaatcccct tacaccaaaa ggcaccttga
    14041 ataagaaata caatattttt aggtagattt ttgccccatt taggagtaac ctgattatcg
    14101 tacatttttt cagtggtagg tccaaaatta gctactagat tagtaatacc aagttctact
    14161 tgtagtcctt caataagtcc atagattgta ggccaccctg ttcgcccatt ttctggaacc
    14221 ttatcaaacc ctgtaacatt actgtatttc ttgtttagcc atttctgagt acttaaaacc
    14281 atctcatcca taaaaatccc ctgctttctt gccgaacata cgttcgttta tgtgttgatt
//
LOCUS       DACGEU010000067        13898 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.067, whole genome shotgun sequence.
ACCESSION   DACGEU010000067 DACGEU010000000
VERSION     DACGEU010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13898)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13898)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13898
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.067"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(162..2159)
                     /gene="tkt"
                     /locus_tag="IXR40_001992"
     CDS             complement(162..2159)
                     /gene="tkt"
                     /locus_tag="IXR40_001992"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HAQ4361828.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPLGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2261..2512)
                     /locus_tag="IXR40_001993"
     CDS             complement(2261..2512)
                     /locus_tag="IXR40_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HAQ4361829.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2659..3282
                     /gene="lexA"
                     /locus_tag="IXR40_001994"
     CDS             2659..3282
                     /gene="lexA"
                     /locus_tag="IXR40_001994"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HAQ4361830.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3462..3680
                     /locus_tag="IXR40_001995"
     CDS             3462..3680
                     /locus_tag="IXR40_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361831.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(3969..4481)
                     /locus_tag="IXR40_001996"
     CDS             complement(3969..4481)
                     /locus_tag="IXR40_001996"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HAQ4361832.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4495..6792)
                     /gene="recJ"
                     /locus_tag="IXR40_001997"
     CDS             complement(4495..6792)
                     /gene="recJ"
                     /locus_tag="IXR40_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HAQ4361833.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLIHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPAE
                     FLDLVAIGTIADLVSLTDENRILVSLGIDAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSD
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     VMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(6934..7368)
                     /locus_tag="IXR40_001998"
     CDS             complement(6934..7368)
                     /locus_tag="IXR40_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1049 domain-containing protein"
                     /protein_id="HAQ4361834.1"
                     /translation="MKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPLILV
                     IIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQREFRN
                     ERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7378..8166)
                     /locus_tag="IXR40_001999"
     CDS             complement(7378..8166)
                     /locus_tag="IXR40_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAQ4361835.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETNFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8163..9104)
                     /locus_tag="IXR40_002000"
     CDS             complement(8163..9104)
                     /locus_tag="IXR40_002000"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HAQ4361836.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9281..9868)
                     /locus_tag="IXR40_002001"
     CDS             complement(9281..9868)
                     /locus_tag="IXR40_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HAQ4361837.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(10089..11402)
                     /gene="obgE"
                     /locus_tag="IXR40_002002"
     CDS             complement(10089..11402)
                     /gene="obgE"
                     /locus_tag="IXR40_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003126661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HAQ4361838.1"
                     /translation="MSMFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGG
                     DVILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAET
                     GALLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVL
                     ADVGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLE
                     RPQIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNAT
                     ADLLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTN
                     FDHDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11690..12700
                     /gene="gap"
                     /locus_tag="IXR40_002003"
     CDS             11690..12700
                     /gene="gap"
                     /locus_tag="IXR40_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HAQ4361839.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            complement(12785..13720)
                     /locus_tag="IXR40_002004"
     CDS             complement(12785..13720)
                     /locus_tag="IXR40_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAQ4361840.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
BASE COUNT         3848 a         3107 c         2452 g         4491 t
ORIGIN      
        1 ctcaagaaac acaaactaat ccgaagaatt ctttgttttg tcatttaaat gtaacatagc
       61 cgaaaacgaa aagtaatatt gatttattct tctaacacat aaagaacagc tgtctccaac
      121 ttgcagacag ctgttcttat cagtcaaaca attgcttgga tctatgatag ttgattgtac
      181 gtattcacga cattttctac tgtaaatcca aattcttcta aaattttagt gccaggggca
      241 gatgcaccga aatgatcgat tgtaatcgtt gcgccctctg ttcctacgta gcgttcccat
      301 ccaaatgatg cagcagcttc gatagccaca cgtttcttca ctgatttagg aagtacactt
      361 tctttatatt cagaagattg tttttcaaag aggtcaaagc ttggcataga aacaacagaa
      421 acatctttgc ctttttcagc caattctttt tgagctttca cagccaaatc aacttcagaa
      481 cctgttgcaa tcaaaatacc ttctggtgtt tctccttgtg atggagaaag aacatacgcg
      541 ccttttttca ccatttcatc tgctacttct tttgtagaag gcaatactgg aaggttttga
      601 cgactcaata caaggatagt aggcgcatct gttgtctcca tcgctacttt ccaagcagca
      661 cgtgtttcat ttccgtctgc cggacgaatc acttgaacac caggcatgca gcgaacagat
      721 gctagttgtt caatcggttc gtgcgttggt ccgtcttctc cgacagcaac cgagtcatgt
      781 gttaagacgt aaacaacagg agtatgttgg attgctgcta aacgaactgc tggtcttaga
      841 taatcgacaa agacaaagaa tgttccaccg tagatacgag ttccgccatg aagttggata
      901 ccattcatag ccgaagccat tgcaaattcg cggacaccga accagatgtt gcgtccttca
      961 taatgttcag gagtgaaatc tttatctgca gccaccattg tattattgga acctgacaag
     1021 tccgctgaac caccccagaa gcttggtata gctttcgata attcttggat gacttcttta
     1081 cttgaaacac ggcttgcttg actgcttcca acttcataag ttggcaattc tgcatcccag
     1141 ttttctggta gtttgccatc aaaagcatct tcaaattgtt gtgctaattc aggataagct
     1201 tttttataat tggcaaacat ttcattccat gcatcttcag ctttttgtcc ttcttctatc
     1261 atcgtttgat ggaagcgggc agctacttct tctggaacag tgaaatctgg atactcccaa
     1321 ccataaactt ctttagccat cttgatgcca tcttcaccaa gaggagcacc atgaacagca
     1381 gatgttcctt ctttaggagc accatagccg atgactgttt ttacttcgat caatgttggt
     1441 ttgtctgttt cagcttttgc ttcttcaatc gctttagaga ttgcttctag gtcatttccg
     1501 tctttcacta agatatgttg ccagccatat gcttcatagc gagcaccaac gttttctgtg
     1561 aaagcttttg aagttggacc gtctagtgaa atatcgtttg aatcgtataa aacgatcaat
     1621 ttccctagtt tcatatgacc tgccatcgaa cttgcttctt gagatacccc ttccatcaag
     1681 tctccgtcac cgcatattgc atacgtatag tgatccatca cattaaagtt ttctttgtta
     1741 tacgttgctg caaggtgcgc ttctgccatt gccataccga cagccattgc aatcccttgt
     1801 cctaatggcc ctgtagtggc ttctacacca tctgtatgat gtacttcagg atgtcctggt
     1861 gttttagaat cccattgacg gaattgtttc aaatcatcga ttgtcacttg atagccagct
     1921 aaatgaagca agctatacaa cattgctgac ccatgtcctg ccgaaagaac gaaacggtcg
     1981 cggtcagccc agttttttga tgtcgttgga tttactttca ggtgttttgt ccataacgca
     2041 tatgccatag gtgctgcgcc catcggcaat ccaggatgtc ctgagtttgc tttttggact
     2101 gcttcaatac ttaatgtacg aattgtgtta acgccaagtt ggtcaatttt gtcaaacaaa
     2161 ataacccctc ctattaattt aggttttttt tacctttatt tcttacactt tcattctata
     2221 agatgtcaca cgaaaaagca atctttttca gtatttttta ctaaaagttg tcatttcggt
     2281 tgtgtaagcc ttttttcttt tggatttctt ttaatttttc cggggtcacg tcattgccct
     2341 caggatcgac gactttcatt ccttcgatat gatgacgcat accggaacga aaagcttcca
     2401 aatactcttt gcgcaagttg atttgttctt gttcttcggc ttttgagaga ccattttcct
     2461 tctttttacg tgcaagttca ttgatccgct ctattttttc aggtgacagc atgctcagcc
     2521 ctccttttac tctccttcat attatataaa aactgaaaaa aaaacaacta gataaactaa
     2581 ataaaatacg aacattcgtt tgatttagcg ctttttatat ggtactattt atttatcaag
     2641 tgaaagaagg tgtaccttgt ggcccgacaa actgaatcaa gacaaatcga agtcttacga
     2701 tatatccatg aacaagtaac ccaaaaagga tacccgccga ctgtccgtga aatcggggaa
     2761 gctgttcagc tttcttctac ttctactgtt cacggtcatc ttgcacggct tgaaaaaaaa
     2821 gggtttatcc aaagagatcc gacgaaacct cgtgcaatcg agttgacaaa acaaggttta
     2881 gaaaagattg ggattcgtcc aacaactatt ccagtacttg gcgtcgtaac agctggagaa
     2941 cccattttag cagtagagga tgcttcagac ttctttccaa tccctcctaa tctttcttcc
     3001 gaagaaggca gtctctttat gctgacaatt cgtggagata gtatgatcaa tgctgggata
     3061 ttggatggtg acaacgtgat cgttcggaag caagaaactg ctcaaaatgg cgatattgtc
     3121 attgcaatga ctgccgagga cgaagcgact tgcaaacgat tctataaaga aaaaaacttt
     3181 ttccgtctgc agcctgaaaa cgacttgctc gaaccaatca tcttagatca agtatctata
     3241 ttaggacgag tagtaggact ttatcgtagt catatctatt aattgctact aattaaaaga
     3301 aaacttttta aaaagagttt gagacgttgg tctcaaactc ttttttcgcc cgggttcttc
     3361 ttctttcaaa tttttatcac ttccctcttt acaaaccgaa caaatattcg tatactaaat
     3421 atacgaacaa ttgttcgcat aaattaaaga ggtgagaatt catgaaatca atgagacgtc
     3481 ttggcttagt attaactgtt ttgtttttag gtattattat tggtaatttc ggcatacgtc
     3541 cagctttact tgtgtttgtt ccgttattta ctttgtggtt catgttgtgg gatgaaaaga
     3601 agtaccgtca atctgagcgg cgcagaattc atgaagatca tttctatcat gagccctact
     3661 acagatccag gcaatcataa taaggattga ctgctaatta ttcaaaagac aagaagttaa
     3721 acttttacgg gggtgtgaca aaaatcggtc acatcctttt tttcgaataa acggtgttct
     3781 aaagccagtt tttcggtatt aagtcaaatt gcggaaaaag tgatttttta aacttctact
     3841 ggtctttgct tgtttccatt tataaaaaaa tagcgaccct caaaagtcag atagagaatc
     3901 tgacttttga gggtcgcttt aaaatcgctt ctttaagaat aacatcaaga atagcttctt
     3961 ttttctgctt aatattccat taatgtaatg atgtcatatc ctttgatttt gtcgcgtcca
     4021 tggagatcca tcaattcgat caaaaatgcg cagcctacga ctacaccgcc taattgttcg
     4081 atcagttcga tcgtcgcttt gattgttcct ccagtagcta gcaaatcgtc acaaatcagc
     4141 acacgttgac ctggtttaat ggcatcctta tgcaatgtca atgtatctgt tccatattct
     4201 aatccataag tcacttcgat ggtttctcga ggtaacttcc cttttttgcg gactggggca
     4261 aaaccgactc ctaactcata agcaacagga catcctacga tgaatccacg ggcttctggc
     4321 ccaactacca tatcaattcg tttttctttt gcataattta cgatttgttt agtagcttcc
     4381 cgataagcgt caccatctgc catcagtggg gaaatatctc gaaacacaat tccttttgac
     4441 ggatagtcgg gaatactggc aatataatct tttaaatcca ctctttgttt cctcctaggt
     4501 tgttaaccat ttctttatgg taggaatatc gctcaaaagc aaaaattcct caactttgat
     4561 tttattgagc cgtcgctggt ataatctgct ctcagtcaaa ggatgacttt ctgggctagc
     4621 gactttttgt aaaacaccgt tctctattgt aacaaatttc aattcaaaaa acacctgtat
     4681 cataaaaatt aataattttt cagggatacg caaatattga gctattgctt ttattttatg
     4741 acgtatatca attcgttctt gagaatggat caatttaaac aattttgcgt actgttctct
     4801 tgtgcctacc ccattcaaat aggcctcatc aggtgaaatc cccatcagat aaacacgatt
     4861 gaatgaataa gaccgaaaaa cttctttcag atccgctaaa tcatctggac aatccataac
     4921 aactagagag tttggttttc ttttttcaat tattgccttt acagaatcta gtccttcgaa
     4981 aacaatcgca gcttcctgga taatctcagg cacgaatttc aacgtcgaag aatcaaatgc
     5041 taaataaagg ctaccttccg acgttcggct ctgttcacgg aaacgttttg cccgccaatc
     5101 aaatacttgc agaccaccca cagaaaaatc agataccatc agctgcggtt tcttacgccc
     5161 gttccattca ttgatcgaaa gctttcctac cacatctacc tgattattca gcagttcttc
     5221 ttcttgagta ccaaaaccaa aagcgaccgc atcaagctga ctcgatgcat cggaaaggac
     5281 aaatttcaga tgctgttggt ttgctccgat tcttttgata ttttctgctt ggacttgtcg
     5341 aaataaaaac tgaggcaaag gattatccgt accaaatggc gccaatagtt tcagctcatc
     5401 aattcgctct actgttactt catttggcag caatacttca tcaattctca actcaggccc
     5461 tctcatcaag tcaatttgat gatcgactat atattggttc atcttctcct gtagtatagt
     5521 gacattttca cttggcatcg ttaaaccgac tgctgcatga tgtcctccga agtaagtaaa
     5581 taaatctcgc atctggtcaa gcatttcaaa aagattcaag gcttcaatac tacgtccaga
     5641 tcctttagct gatccatctt cttttaaagt aaggacaagc gttggtttac ccgtttcatt
     5701 cattattttc ccagcaacaa tgcccaaaac gccttcatgc catcctcggt ttaccaatag
     5761 atggatatga ttctccttat tgaccatcgc taatgcttct tgtgttatct gctctacgat
     5821 tgcttttctt tcttcattga tctcattcaa tttttttgct tgaacggatg cttcctcttc
     5881 atcaaacgtc gcaagtaacg agacggcagg acgtggatcg cccatccgac cgattgcatt
     5941 tagtctggga gcaatcgaaa aaccgatcgt tgtttcgtct gcgtccctca tttttacgcc
     6001 gctttcttca aatagcgcct gaagtcctat ccgttctgaa tgatgaatgg catcgattcc
     6061 taatgaaaca aggattcgat tctcatcagt caatgaaact aaatcggcga tcgttcctat
     6121 cgctactaaa tccaaaaatt ctgcaggcgg ttcttccaat aatgcagaag ctactttgaa
     6181 tgctactccg actcctgcca aatctggaaa tggatagtgc cccgctggat gacgagggtg
     6241 aacaatcgca taagcgtctg gtaaattctc aggtagttcg tgatgatctg taatgatcac
     6301 gtctacacca gcttgctgag cgtatgctac cgcatcattt cctgctaccc cgttatcaac
     6361 agtgatgatc aactggattc cttcttcgat cttttcttgg tataccgatt ggtttggtcc
     6421 atacccatgc tcaaatcgat ttggcaggaa tacttctact tctgcaccaa gtaattccag
     6481 tgtttctttc attaccgttg cactggtgat cccatctgcg tcataatcac cgtaaacgag
     6541 gattttttct ccactgatta cagcttcttg gattcggctg attgctttat ccatatcgtg
     6601 tatcagatac ggatcatgta attcttgttc ctttggatgt aaaaatcggt tgatatcctt
     6661 ttcctcatgg taacctcttt gccacagtaa cttaccgaca aatggagata atttcagttc
     6721 acggatcatt tggagaaagg attcagaagg ctctgtctcg cttaacttcc aatcaaaatt
     6781 tgcttgtctc actttctcac tcctaactta gttattatag caaaggaaat cagcaaaaaa
     6841 aagcagaaag aaagaataaa aacagatcag atccgctaga cagatgttca gcaggacctg
     6901 atcttttgta cgaccattta tgaaatatcc ctattagtca aaataattga agctttgttt
     6961 gggcgattga gttttttgtt cttccggcgc tttcaattga ctgatttgtg cggttttcgc
     7021 ttgtaactcc gcctgataag cagcttccaa ctccgcacgt tcgtttctaa actcgcgttg
     7081 ctgttcttct tttgcttctt caattttctt ttgaagttct gtttgatatt ctgacatttc
     7141 ctgagtcagc tgtttgattt gctttttttg ctgccatagt gttgccgaag cagtcaaaaa
     7201 tacaatcagt gcaccaatca gcgcagaacc gatgatcact aagatcaatg gcgcagaaaa
     7261 ggaagtgaag ccaaaactta caggaacatt tttattgttc aatacagcaa aaagaacaat
     7321 aatcaaaact aaaacaaatc caagaatcac attgctttgc tttttcaatt ccttcaccta
     7381 ctttttgtta aaaattccgc tggctaaata atcaccaatc gttggaaaca gcgtataaaa
     7441 ttttgatgca acttctaaaa taaacggttg attgatttcc cgttttggat gtctcatatt
     7501 gcggacgatc atttttgcca acttggcagg ttctaaaacg atttgtccga ctttttccaa
     7561 atagcttccg cttggatcag ccttatcgaa gaaatttgtc tcgattggac ctggattcac
     7621 tgtcgtaaca gctacgccaa gtggtttcaa ttctaatcgc aaagcgttgg agaagccaag
     7681 gactgcaaat ttcgtggcag aataaaccgt tgattttgca gttgccattt ttccagccat
     7741 agaggcgata ttaatgatat gaccttgtct tctttctgcc atatcgatcg caaatttttg
     7801 tgtcaaaacc atcattccta agatgttgac ttcaaacata tcgtatgctt ttccaaggtc
     7861 gaatgtaagg aagtcttcga aaatcccaaa acccgcattg tttaccagaa tatcgacgcg
     7921 cccgacttct tccatcacct tttcatataa ttcgtccacg ctttcaggat tgctgacgtc
     7981 taccttgaaa gcataagcct ctttgccgct caagcgtctg cactcgtctc tgacaccttc
     8041 tacaaatgcc attcttcgtg cgcaacttat aacgattgct ccttgctttg ctgcttcata
     8101 acagatttgt gcgcccagac cgcctgaact acctgttact aaaacaactt tatcttctaa
     8161 attcatgcct cttcctcctc gcgaaatgga atctcaatgc tatcaaaatc tttcataatc
     8221 gtcgtgtttt caaacacttc ttgtgcttct ttttcaagct ctaaagctgc ttttcctaaa
     8281 tatctcgcac tgatatgagt aagtagcagc cgttttgcct gcgcttcttt tgcaacttca
     8341 gcagcttgat gagtcgtgga atggaaatag ttgtgcgcca ttcttgcttc atctttatta
     8401 aatgtgcttt catgtaccag aatatcgcta ttttccgcaa gcacaacgga attatgtgtt
     8461 tttctcgtat cgcctaaaat agtcacgatt cgtccttttt tatctggacc tacgaaatct
     8521 tttccattga tcgtccgccc atcttctagt tggatcgttt caccttgctt cagtttgccg
     8581 tacagtggtc cagctggaat acctaattct tttagacgat ccacctgcaa ttctccttta
     8641 tgatcatgtt caaccacacg ataaccaaaa ctgtcgatcc catgatttag tttttttgta
     8701 taaacagaaa attgctgatc agtaaaaatc ggggctgttt catttagctc aatgaatttc
     8761 agcggataac ttaaacgcgt ttgcgaaata cctaaagaga cttttatgta ttcctctatc
     8821 ccttttggcc cgtaaatctc taatggcgta tccccacctt gaaatgaccg gctgctgatg
     8881 agcccgggaa gtccaaaaat atgatcgccg tgtaaatgtg taatgaaaat tttaccgatt
     8941 tttctcggac gaatagtcgt tcgcaaaatc tgcatttgcg tgccttcgcc acagtcgaac
     9001 aaccaaactt cattgcgctc gtctaaaagt ttcaatgcta tacttgtcac atttctatgt
     9061 tttgcaggaa cacctgcacc tgttcctaaa aattgtaatt ccataatcta cctgactttc
     9121 tttaagttcc tctttaattt tagggtaaaa agaagggata atcaaccgta agtcgagaat
     9181 gggttcaaat taaaaataac gttctaaagc gatagcgttt tctttgaaaa ttactataaa
     9241 aacagcagcg aacccgtttg agatcctctg ctgtttttta ttaatttgaa gatccagaac
     9301 tttcattgtc gttggaagtt tgcggatgtt tgtccttcca agtcttttgt gcagcttctt
     9361 tcgcatgatt ttcagcttct ttcgcatcat gcacatcttt ttcgacatct tcataatcca
     9421 agcgagtaat ttctccgcct aattccatca ttaccaattg attcagtggg cgattgtcct
     9481 cttcatcagc aatcaagatc agtcctgtag ctccttcacc gattttattt cctacaaagt
     9541 cgaacacggt ctgggcatct tttatttctt tggcatcttg tgtcgcaccg atcattcctc
     9601 cggcaaacca tcctaataaa atccctagcg gaccacctaa tacaccaacc aacattccga
     9661 ttaatccacc cgtagaagat ttgttattac cggtaaagtc gataaaatct tctattttga
     9721 attgatgtgt cccattagga tcatggctga caactgccat ctgttctcct ttaatcgaac
     9781 gaacagcatg taactttttg atttctgaaa atgcctgata tgcctggctt tctacttgaa
     9841 aatttaaaat gattactcgt ttgctcatta aaaacgcccc tttcatacct tcttgttatt
     9901 tattttacct ttaattgaaa aataagaaaa gaaaagcact ctttttttcc aataaaatag
     9961 ggctgtgaca aaagtcgtat cacagctcct ttttccgaat aaacggcgtt cttgaagctg
    10021 atcacttctg tcacaacctc ccttaaatct gaatctatat tttttggtat ttgtttttat
    10081 ttgcttgcct attcgacaaa ttcaaattca aactcaccga tacgtacaag gtcgccatct
    10141 ttcgcaccgc gtgcccgaag agcttcatcc acacccatac cacgtaattg acgagcaaaa
    10201 cgcatcactg tttcatcatg atcgaaattc gtcatttgga ataatttttc gatcttctca
    10261 ccagataaga tccacgttgc atctgaatca cgatcgattt ggaactcagg accttctgga
    10321 ttgaatccat agtgtacagt ttcttcttcc agttcttctt cgtacaatgg gaattctggc
    10381 gttacttcta acaaatctgc tgtagcattc aataacgcgt ccaatccttg tcgagtcact
    10441 ccagaaattg gaaatactgg gatgtcatca gcaaattcat cttctttttc cttgttcagc
    10501 tgttctttga atttcactag attttccggt gcatccggca tatccatttt gtttgccacg
    10561 atgatttgcg gacgctctag caagcgtaag ttataagtag ataattcttt gttgatggca
    10621 agatagtctt cataaggatc tcgtccttcc atcccactca tatcgatcac atgtaaaatt
    10681 actcgtgttc tttcgatatg acgaaggaat tgtgtaccca gcccaacacc ttgcgaagct
    10741 ccttcaatca agcctggcaa gtctgctgcg gcaaaacttc tgccatcact tgtagtaacc
    10801 attcctagat taggtacgag cgtcgtgaaa tgataagcgc cgatttttgg acgagcagat
    10861 gaaataacgg atagtaaagt cgatttcccg acagatggaa aacctacaag tccaacgtct
    10921 gccaatactt tcaattctag ttcgattttt cgctcttgtc ctggttcacc gttttcagca
    10981 atttccggtg caggattccg aggagaggca aaacggatat tccctcgtcc accgcgtcca
    11041 ccttttgcca caactagtgt ttgaccattt tcaattaaat ctcctaaaag agcaccagtc
    11101 tccgcatctc ggacagtggt tccttgtggt actttaacat aggtatcttc tgaaccacga
    11161 ccgtgcatcc ctttactcat cccattttca cctggctgcg ctttgaaatg gcgattgaac
    11221 cgaaaatcca tcaatgtacg taacccttca tcgacgatca agatgacatc gccgccacga
    11281 ccaccgtctc cgccagccgg tccgccgtca ggaacgtatt tttcgcgacg aaatgcaacc
    11341 attccgtctc cgcccttgcc agctttcaca tcgatcgtta cttgatctaa aaacatggac
    11401 ataattaagt cctcctatta ttcatttatt tatttgactg cctgaatttc cacaataaac
    11461 aaaagtctta cttattttat cggtgaaatc tgattttgtc tatcatttca gcaaaaagat
    11521 tgtttacctt cttctttttt tatcatttgg taaggtttcc aacctttttt ctgctaccaa
    11581 gtataatttt ttgacaaaat attctttgcg tagcagaata acagtgtatt aattgtatta
    11641 attgaggatg ccgtttcaca gcacccctaa taaaggagga acttttgata tgacagtaaa
    11701 agtaggtatt aacggatttg ggcgtattgg ccgtctggct ttccgccgca tcaaagaagt
    11761 ctcagatgat attgaagtag tagcaatcaa cgacttaaca agtccaacta tgttagcaca
    11821 attattgcaa tttgactcta ctcatggtac ttatcctggc acagttactg caacagaaga
    11881 ctcaatcgta gtggatggcg aagcaactcg tgtttatgca gaacccgacg caagcaaaat
    11941 cccttgggca aaagaaaacg gtgtagatat cgtactagaa tgtactggtt tttatacatc
    12001 tgaagaaaaa gcaaaagcgc atttagatgc tggtgtcaaa cgagtagtta tttctgcccc
    12061 agctggtgct atgaaaacca tcgtctataa cgtcaatgat gatacattag atgaaaacga
    12121 caaaatcatc tcagcaggtt catgtacaac aaactgttta gcacctatgg cttatttctt
    12181 aaataatgaa tttgggatcg aagttggtac aatgacaaca gttcatgcct acacttccac
    12241 acaaatgctc ttagatggac ctgtaaaagg cggtaatttg cgtgctgctc gttcagctgc
    12301 tgacaatact atcccacatt ctactggtgc tgcgaaagca atcggcttag ttatccctga
    12361 gctacaagga aaattacaag gacacgcaca acgtgttcca gtcgttgatg gttcattaac
    12421 tgaattggtt tcagtattga aaacaaaagt aactgctgat caagtaaacg aagcaatcaa
    12481 aaaacacaca gttgacaatc cttcattcgg gtatgatgac cgtcaaatcg tttctagcga
    12541 tgtcattgga acaactcaag gttcgatctt tgacccaacg caaacagaag taacaactgc
    12601 tggtgatttc caacttgtta aaactgttgc atggtatgac aatgagtatg gatttacttg
    12661 ccaaatgatt cgcttactag aaaaattcgc taacttgtaa tttgatagat caatcgataa
    12721 aagaagcctt tgactggatc cagtcaaagg cttctttctt ttcatcccct acttttaaac
    12781 tcgttcaatg aacatattgg cttaaaaatt gttggactac ttgctgatat ttttcaggat
    12841 ctgtcttgta tgcttccgca tgctcggctc cttttacaac atacttttct tttggtccct
    12901 tcgttgcacg atagacctta tctaacattt caaatggtac aaatgtatct tcgtctccat
    12961 gtataaagag cattgggcgc tggtttttct tcaattgttc cactgcattt gcttcaccga
    13021 aaaagtagcc agcacggact tttgtcacta gactcgttac ttgcataagc ggaaatgctg
    13081 gaagactaaa catatcgtct agctgataag caagctcatc atgaacggaa gaataaccgc
    13141 aatcttcaat gattgctttc acattatctg gtagtttttc tccgctagtc atcataactg
    13201 ttgctgctcc catgctgaca ccgtatagaa cgatttcttg cgattttcca ttgttttcta
    13261 gcactttgtt tatccactgt acatagtctt tacgctctgg ccatccaaat ccaatgtaat
    13321 ccccttcgct ttttccatgt cctcttgcat caggaacaag gacattgtaa cccatatcat
    13381 gaaacatctt tgcgtaattg gtcatcgttt cagcgtttcc catatagcca tgagccacaa
    13441 gagctgtttt ttcacttttc gtttcagcag gaagataaat cgctgataat ttcagaccgt
    13501 cttttgaagt gatggtccaa tcgcttcggt tttcttttga actaaaccat ttatgtgcat
    13561 ccgtttcttt ggatgtctgt gttgtaccag gtgtatcttc gtctaaaaag tctttctcag
    13621 aaggcacaac agcataatta taaaaataat tccctgcaaa cactaacgca acaatcagag
    13681 ctaaagcgac gcctaaaagg attttcatcc aaagtttcat aaatcatcca tctcatttct
    13741 cttttttcat ataaccttga attagtataa tcaaagaatc tctactatgc aatgttcatt
    13801 tttataaccc gcgaattgta aaattaagtt agaaaaataa aaaggcattt atggtacact
    13861 caaattgtat ttccgacgaa agaaaacaaa ggagtgta
//
LOCUS       DACGEU010000068        13756 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.068, whole genome shotgun sequence.
ACCESSION   DACGEU010000068 DACGEU010000000
VERSION     DACGEU010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13756)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13756)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13756
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.068"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            16..2181
                     /gene="acm"
                     /locus_tag="IXR40_002005"
     CDS             16..2181
                     /gene="acm"
                     /locus_tag="IXR40_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HAQ4361841.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIGLLIVTICAGIFLQKYKKV"
     gene            complement(2453..2938)
                     /locus_tag="IXR40_002006"
     CDS             complement(2453..2938)
                     /locus_tag="IXR40_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HAQ4361842.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     gene            3418..4059
                     /locus_tag="IXR40_002007"
     CDS             3418..4059
                     /locus_tag="IXR40_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAQ4361843.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIVMKQVEGKLNYYR"
     gene            4078..4713
                     /locus_tag="IXR40_002008"
     CDS             4078..4713
                     /locus_tag="IXR40_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAQ4361844.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            4731..5546
                     /locus_tag="IXR40_002009"
     CDS             4731..5546
                     /locus_tag="IXR40_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HAQ4361845.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            5865..7301
                     /locus_tag="IXR40_002010"
     CDS             5865..7301
                     /locus_tag="IXR40_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAQ4361846.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            7490..9937
                     /locus_tag="IXR40_002011"
     CDS             7490..9937
                     /locus_tag="IXR40_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HAQ4361847.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            10167..11234
                     /gene="rlmN"
                     /locus_tag="IXR40_002012"
     CDS             10167..11234
                     /gene="rlmN"
                     /locus_tag="IXR40_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HAQ4361848.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(11427..12530)
                     /locus_tag="IXR40_002013"
     CDS             complement(11427..12530)
                     /locus_tag="IXR40_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HAQ4361849.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            13082..13630
                     /gene="aac(6')"
                     /locus_tag="IXR40_002014"
     CDS             13082..13630
                     /gene="aac(6')"
                     /locus_tag="IXR40_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HAQ4361850.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         4709 a         2298 c         2914 g         3835 t
ORIGIN      
        1 ggggagatag aaaaaatgaa aaagtgtaga aatattattt tatcaatgtt atttattatt
       61 actaatataa catcactgat tcctgttcat gtctatgcgg atgcaggcag agatatcagc
      121 agtaatgtca cttcgttgac cgtggaccca acgaatatta cagatggagg aaacataaaa
      181 gtaaaattct cgtttgacga aaaaaaacaa aatatccaac caggtgatta tctttggatc
      241 aattggccaa gtgaaggaaa tattcgcggt gaaggattcc aaaaagaaat cccattaatg
      301 attgaaaata aaaatgttgg aactttaacg gtcagaaaag attctgcgca ggttgtgttt
      361 aatgaaaata ttaaaaacct agactcagta gaaggttggg ggcaatttga gatacaggcc
      421 agaaacgtaa ccgataccgg tgaagaaaat acgggaccat tcaccgtgac gagcggtgat
      481 aaaacagcta ctgtaaatgt gacaaagcca gcttctggtt cttcttctag cgttttttat
      541 tataaaacag gagacatgct acctgaagat actaagcaca ttcgatggtt tttgaatatt
      601 aacaataacg gcacttatgt tgaacaacca gttaaaatca gtgatgaaat ccaaagtgga
      661 caaagattag atccaagtac gtttgaaatt aatcaaatac acttaggtga acagaaggtt
      721 tatagaggag aagagggaat ccaacaattt ttacaagatt tccccagcgc tacatttaat
      781 ttttcagtaa ctgataatta cattgaaata actataccaa aaaactttgt caatcttagg
      841 aaaataatgg tgagttataa gacgatcata gaaaacccag aacaaataaa ttttgagaat
      901 cattcggaag cttggtttaa agaatttaat aaacctgctg ttgatggaga aagtttcaat
      961 catacagtta aaaatatttc agcttctggt ggagtcaacg gtacagttag aggcgaattg
     1021 aagattttca aatatatcaa tgacacagag attggtatcc caaatgtgac tttcgaatta
     1081 agacgagcag atgaacagcc tattcaagga cagtctagta tcctgttgac ttcgaatgaa
     1141 cagggagaag ctagtatcaa aggcctgcaa gtaggagact atgttgtaaa agaaaaagaa
     1201 gcacccaatt ggattgattt tgatccacta agttcaaatg aactcaaatt ctccataaac
     1261 gaaaatgata cagagggagt cagtttacct atttataaca agaaaaaggt tacgaacatc
     1321 acagcaacta aaatttggaa cggtggaacc actccaagac cgagtattta ttttaaatta
     1381 ttcagagcaa gtacaaacaa ttgggaacca gttcctgatg cagaaacaaa acgattagac
     1441 aatggaataa cttcagtgac ttgggaagat atccaacagt atgatgatag tggaaacgaa
     1501 tatacgttta aagtgcaaga agtagatcaa aacggaaatg attatgtccc ttcaggttat
     1561 caaaaaattg aaaacgggct agtcgttaca aatgagaata aagaagtcat ttcagtctca
     1621 ggacaaaaaa catgggaaga caatgagaac caagacggca aacgaccgac gacgatcaca
     1681 gtaaatctat tagccgacgg tcaaccgatc caacacaaag aagtaagtga aaaagatgat
     1741 tggcgctatc gtttcacaaa tctgccaaaa tacagagacg ggcaagaaat catctatact
     1801 gtaacggaag acaacgtgcc cgaatacagt acgacgattg acgggtataa catcaaaaac
     1861 agttatacac cggaaaaaac aaatatatct ataccaggta gccatataac accgtggaaa
     1921 aattttccag agaagacaga gagagagaaa attagaaatc tattctctca aaaattgcaa
     1981 atatttgctc atacaggaga atccagcgaa caaagaagca attatattag taagagagct
     2041 gtacctaaac agataacaaa taaatcaaaa agcattcttc ctaaaacaag tagtaaaaaa
     2101 tctagttttg ctgtaatcat tggtttattg atagtaacta tctgtgctgg gatattctta
     2161 caaaaatata aaaaagttta gttagaatat aatatttttt gttaaatatg actgaaatca
     2221 aaagaataaa attccgattt ataatcgaaa aaagaagcat ttttatatat gcttcttttt
     2281 tcgtagaatc aataaatatg gatttggcta actatggaag aatactcgta ttagttttca
     2341 gcgttcatac tagttgttac attgtttgat tggccaaaag aatttctgat atattttgtg
     2401 ctaaataaag aaaaagacgc ttgaattggg aaataagaaa actactctat cattacaaat
     2461 tttcataaac tggcagatgt tctaagtaaa caagtatctt ttcaaagtcg gaaaaatcca
     2521 taatcaacgt agtggtattg atatttggat gaaagcctac ggtatcttga cgatcaatag
     2581 cagcatcgat cacgacttgg atttttttct ctttgtcgtg catcaatgct aatggagtca
     2641 ctgtacctgc tggaacgcct aggaggtcag gaagctgttc ttcagaaaca aaagataagc
     2701 gcttttcttt taattgttca gctagttgtt ttaaatcggc gtgcttttca tcaggcaaga
     2761 tgacaagata gatttgtttt ccttttcttg atttcaataa tagatttttt acttgcggac
     2821 caggtaggga aaaagggaca tttttgactg acgtaatcgc aggatgatcg actttttgaa
     2881 aagagatacc cagttttttt agtagttcat aagcttcttg ttcggttgca cgactcatcg
     2941 cgcatcaccc tccttttttt attagtgtat cataaaaaag agttgacaaa tgaaaaataa
     3001 tcatgtaaat tacacgtaaa gttaaaacaa atgacatcga aaagaagagt agccgttagg
     3061 tgtttttaga gagtctctgg ttggtggaaa gaggcagcag ttaaccgtga aacacatctt
     3121 ggagtcgatt ttctgaagcg tatagtagga aaatccgggg agcccgttac agctgcggtc
     3181 gttgctagat gaccagataa ggctggcttt tccgtgagga gtcggtaaaa aaaggtggaa
     3241 ccacgtgatt aacgtccttt gatcttcgga tcaaaggact ttttgttttc atctgaacgg
     3301 caacgactgt gtgaggtttt ttctgcaagg aaaaaataaa cagaggtgga accacgtata
     3361 atacgtcctc ttggcatttg ccaagaggat ttttttattt taaaggagga aaagaagatg
     3421 gagtatttga ttgaagttat gccgcaatta ttagtaggag cactcacaac attgaaatta
     3481 tttttattta ccttgattgg ctcattacca ttagggattg ttttagcatt aggattgtct
     3541 ttgcatttta agccgctacg ctacttgctt caaacatatg tatgggttat gcggggaaca
     3601 ccgctgttgt tgcaactgat ttttattttt tatgggttgc cgacgattgg gatcgttttt
     3661 gatcgtttcg aagcagcact cattgccttt atcttaaact atgcagctta ttttgcagag
     3721 atctttcgtg gagggataca atcgattcct caaggtcaat atgaagcagc gcaagttttg
     3781 caattaagtc cctttcaaac ggtgacgaaa atcgtcatcc cacaagtgac aaagattgtt
     3841 ttaccttctg tagggaatga agttatcaac ttggtcaaag attcttcctt gatctatata
     3901 ttaggtttag gtgacgtaat gcgtgctggg aaaatcgcga tggaacgcga cgcgacttta
     3961 ctgcctttgc taggcgtggc aatcatctat cttacattga ctggtattct aacaatcgta
     4021 atgaaacaag ttgaaggaaa attaaattat taccgctaac tgataggagg aagaaatatg
     4081 attgaattga agaaagtgaa caaagcattt ggtgaaaaaa aaataatcaa agatttgaat
     4141 ctaatcattc cagatgggaa aacattagct atcgtaggtc cttccggtgg cggtaaaacc
     4201 acgcttttac gtatcttggc tggcttagaa agttctgaca gcggagaatt ttatttagac
     4261 ggtgtaccgt tcaacccatt cgagcttaaa atgaaagaac aagttgtagg agtcgtattc
     4321 caagacttcc agctatttcc acatctgaat atttttgaaa acattacctt agcaccaaaa
     4381 atggtattga aacagacaaa agaagaatac accaaaaaag cagaagaatt agcggcttca
     4441 ttagggatta gtgatttatt gaatatctat ccttatcagc tttctggcgg acaaaaacag
     4501 cgggtagcga ttgccagagc attggctatg aatccacggg tattggctta tgatgaacca
     4561 acaagtgctt tagatcctga attacgccag caagtcgagc gtttgatcct atcattgaaa
     4621 gaagatgggg taacccaaat tattgtcacc catgatttag tatttgcaga aaatgtcggt
     4681 gatcaattac taaaagtttc cccaattcat taagaaagga gaagatagag atgaaaaaaa
     4741 ccagttttct attcgctttg atcgcaggtc ttcttctttt tgcaggctgt tcgaacaaaa
     4801 aaacttcagc agataattgg gcgactatca acgaagagaa aaaaatcgtt ataggtttag
     4861 acgatacatt tgttcctatg ggatttagag ataaagacgg gaagctcaca ggatttgata
     4921 ttgatttagc caaagcagtc tttgaacaat atgggattac ggtagacttt cagcccattg
     4981 actggtcaat gaaggaattt gaactgaaca atggaacgat cgatttgata tggaacggct
     5041 attccaaaac gccggcaaga gaaaagaaag tgcaatttac aaaaccttat atggaaaacg
     5101 atcaagtgct gatcacacct aaagaatcag gaatcacaaa ctttggacaa atgaataata
     5161 agagattagg tgcgcaaaat gggtcatctg gttatgatgt atttacgaaa caaccagaag
     5221 tattaaaaga gatagtcaaa aaccaagatg ctgttttgta tgatagtttt aatgaagcat
     5281 tgatcgatct gaaaagcaga cgggtcgatg gtctgctgat ggataaagta tacgcagact
     5341 attatttgaa acaaagaaac gaactagaag acttcaacat aacaaaaggt tcttatgaga
     5401 gtgaggattt tgcagttggt gcacgcaagt cagatagtac attagtgaaa aaaatcaatg
     5461 aagccctaga tcaactagag aaaacaggtg aattccaaaa aatatccgat aaatggtttg
     5521 gcgaagatgt tacgccgaga aattaacaaa taggggactg tgacaaaaga cgtgtcacag
     5581 tccctttttc cgaataaaca gtgttctcct gccaactcct tgtgactcgg agctgaatgg
     5641 caggctcaca acctcttggt aaacggtgtt caaaagccag tttttcggta ttaagccaaa
     5701 tttatgcaaa aatgtagaaa gccattttca caaaattttt cttactactc gaaactaagc
     5761 gactttttca caacctcctt tacataattt tattttgttg tggaaggggt ttcgtgttat
     5821 tctaaaagag gaacgattga aggttatagg aaaggaagag atgaatggaa cacaaagaac
     5881 ttacctcatt tccaaaagat tttctgtggg gctctgcttc tgcagcgtat caagtagaag
     5941 gagcttggca agaagatggg aaaggagaat cagtctggga tcgatttgta cggatacctg
     6001 gaaagacatt taaaggaacg aacggtgatt tggcagtaga ccactatcat cgttataaag
     6061 aagatattgc tttaatgaaa gaacaaggtc tgaaagctta ccgcttctct gtagcttgga
     6121 cacggatttt tcctaatgga cgaggagaag tcaatcaagc tgggctcgct ttttatgaga
     6181 gattgatcga cgaattgatt gaaaacgata ttgaacctat gttgacttta tatcattggg
     6241 atcttccaca agcattgcaa gatgaatata atggttggga atcacgtcag atcattgaag
     6301 atttcactca ttatgcagaa acattatttg aggcattccg cgggaaagtc cattactgga
     6361 ttagtttgaa tgaacaaaat atcttcactt cattaggtta tttgttagca gcacatccgc
     6421 caggtgtgac agacccgaaa cgaatgtatg aagttaacca tattgctaat ttagcaaatg
     6481 catctgtcat caataaattt cacgagttag aaatgcctgg aaaaatcgga ccaagctttg
     6541 cgtatacgcc aaattatcca attgacagta atcctgaaaa tgttctggct gctgaaaatg
     6601 cagaagacct gatggccaat tattggatgg atgtctatat gtggggaaaa tatccgattg
     6661 ctgccatgag gttcttagaa gaaaaaggat gggcaccaac gattgaagct ggcgatgcag
     6721 aattgctaga atctgctaaa ccagattttc ttgggatcaa ttactatcaa acggcgacga
     6781 atgcattcaa tccattaaac ggagttggtg ctggaaaaat gaatacgaca ggaaaaaaag
     6841 gttcatcaga agaaactgga gttcctggaa tgtataaaaa agttgagaat ccatttgtcg
     6901 aacgaacaaa ttgggactgg gagattgacc cagaaggatt aaggatcgga ctgcgtcgta
     6961 tcacaagccg ttaccgcatg ccggtactga ttacggaaaa tggcttagga gagtatgaca
     7021 agttgacaga agataaacaa atccatgacg actatcgaat caattactta caaagccacg
     7081 tcaaagccat caaagaagca atttcggatg gagcagaagt cctaggctat tgcacctggt
     7141 cttatacaga tttgcttagc tggctgaacg gttatcaaaa gcgatatgga tttgtatatg
     7201 ttgatcaaga cgaaacacaa gaaggatctt tggaacgata taagaaagac agttattact
     7261 ggtaccaaaa actgattgaa gaaaatggag agaaccttta gttcacatac ttaaaacaag
     7321 aaggtacggc tggatatggc cgtgcctttt cttgataaaa tcatttagaa attaagaaaa
     7381 actgtaaaat aagctgaaaa atgaaagaaa gcgtcagttc tttcaaacaa aactttagtt
     7441 cccttacttt tttttgtata atgaaacttg atgaaatgag ggataataaa tggcacaaaa
     7501 gaaacggcct actaaaaaaa ggaaaaagac gaaaaaaacg aaaaagcaaa aacagcagca
     7561 ggaacaaatg ctgacgattg gtgttgggtt tgccttgatt ttatttgctg tcttcggctt
     7621 tttaaaatta ggttttttag gaatattgat tgcaaacggc tttcggatca ttgcaggaaa
     7681 tacttaccaa atcctctgtc ttttattagc cgtattagga ttttggattg tcattaagaa
     7741 tacagagttt tcaattggta aaaaccgacg ctggtttggc ggcatactct tttatttcgg
     7801 tatcttatta ttgttacatg cccatttatt tggcaaactc catactgggg aaccaaatat
     7861 catggggacg acatgggatt tgttagccag tgatataaaa caaagtcaag tagacaataa
     7921 cgttggtggt gggatgattg gagcaatcct ttatcatttt acttacttct tgattgcaca
     7981 gcctggaagt tatttagcag cagtgctatt actggcagga ggagcattcc tgttcagtaa
     8041 tctggaaggc tatcagctgt taaatggtat ccaatcaatt ggagaacgag tacaggaatt
     8101 attggaaggt gatcctgcca agcaagctcg aaagcaagcg gcaaaggaag agagaatgaa
     8161 acagcgcgca gaagcgaaag aagcaaggcg cttagctgca aaagaagctg cagaaaaaga
     8221 agctgcagaa tatgagaaga aaaaagcggt gagccagcaa agggaaaata ctgctgatga
     8281 atggcaggaa ccagaaaata cagagccgga gcagctaagt tttgttccaa tcgacagttt
     8341 tcaagaaaat atccatcctg cgaatctaga gaaaccagta ccagatacac caaaacagac
     8401 caatacagca gaaggttttt cagatgagtt gccagaggat gacggtacct cattagaatt
     8461 tgagattgaa gcagaacagg aaaatcaaga ctatgaatta ccgacagttg atttgcttga
     8521 ttctatacca actgtggatc aaagtgatga gtataaaaaa attgaaaaaa atatcggcgt
     8581 attagaacaa actttccaaa gtttcggtgt cgatgccaag gtcgtcaaag ccagcttagg
     8641 accatccgtc acaaaattcg aagtccagcc ggctgtaggg gtaaaagtaa gtaaaattgt
     8701 gaacttaaca gatgatatcg cgcttgcttt agcggcgaaa gatgtccgga tggaagcacc
     8761 gattccaggt aaatcactga ttggtattga agtaccaaat ggaaagatca gtatggtttc
     8821 ctttagagaa atcatcgaag cacaaccaaa ccacccagat aaattactag aagtaccttt
     8881 aggacgtgat gtttctggac gggtacaaac ggctgatctt tcgaagatgc ctcacttact
     8941 cgtggctggt tcgactggta gtgggaagtc agtagcaatt aatgggatta tcacaagtat
     9001 attaatgcgt gctaagcccc atgaagtaaa actgatgatg atcgatccga aaatggttga
     9061 attgaatatg tacaacggca tacctcatct gttgacgccg gtcgtgacga accctagaaa
     9121 agcagcgcaa gccttacaaa aagtagtaca agaaatggaa gaacgatatg aaaaattcgc
     9181 ggcaaccgga gtaagaaata tttctggtta caatgaattt gttcaacaga aaaacttgga
     9241 aaacggaacg aaacatccaa ccttaccatt catcgtagtg atcgtagatg aattagctga
     9301 tttgatgatg gtagccagca atgaagttga agatgcgatt attcgtttag cgcaaatggc
     9361 tcgggcagcg gggattcata tgatcctagc tactcaacgt ccaagtgtgg atgttatcac
     9421 aggaatcatc aaagcaaatg taccttccag aatggcattt gcggtatcaa gcggtacaga
     9481 ttctcggacg atcattgatt ctaatggggc agaaaagctc ttagggcgag gagatatgct
     9541 attcttgcca atgggtgaga ataaaccgat ccgtgtgcaa ggagcattca tttctgacca
     9601 cgaagtagaa cgggtcgttc aatttgttac agatcagcaa gaagctcatt atgaagagaa
     9661 aatgatgccg acagatgaag ttgaaacgac aggtgctcca gaacagccac aagatgagct
     9721 gtttgaagaa gcaaaagcac ttgtcgttga aatgcaaacg gcaagtattt cccttctcca
     9781 aagaagattt cggatcggtt acaaccgagc agcacgttta gtagatgaac tggaagctca
     9841 tggagttgtt ggcccgtcag aaggaagcaa gcctcggaaa gtattcattg agcaggaaga
     9901 aacatcagaa acgttgccgg acgataatga catgtaaaac ttgtgtgatg aagggttgaa
     9961 aaacgaataa ccaataaaaa gacaaggcat gatgatacca aaagaaaaaa tggttttttt
    10021 ccatcttttc taatacggta tgatgtcttg tctttttagt ttttgtgaga ttaaagttct
    10081 attcgattta tttgtgaagt attgcattaa ggaaatgaat catgtatagt atgtagcgaa
    10141 actttgagaa aaagagggaa aatactttgg aaaaacagtc catttatggc ttgacgaatg
    10201 aagaattaat caattggttt atagaaaacg gcgagaaaaa attccgagct gcccaagttt
    10261 gggaatggtt gtatcaaaaa cgtgtaagta atttcacaga aatgacgaat ctatcgaaac
    10321 aattgatcga aaaattatcg gagcatttta tcatcaatcc tctaaaacag atggtcgtcc
    10381 aagaagcttc ggatggtaca gtaaaatatt tgtttgaact ccctgataaa aacatgattg
    10441 agactgtact gatgagacaa gaatatggct tgtcagtttg tgtgacgaca caagtaggat
    10501 gtaatatcgg ctgtacgttt tgtgcaagcg ggctgctcaa aaagaaccgt gatctgactg
    10561 ctggagaaat tgttgcacag atcatgatgg tccaacatta ttttgatgag cgcaatcttg
    10621 gcgaacgcgt ttcacatgtc gttgtaatgg ggatcggtga gccatttgat aattacgaca
    10681 atgtaatgga ctttttgcat atcatcaatg atgccaaagg attggcaatt ggtgctcggc
    10741 acattacagt ttccactagt ggattagcac acaaaatcaa ggaattcgct aataacggct
    10801 tgcaagtcaa tctggctatt tccttgcacg cgccgaataa tgaggtgcga acatcgatca
    10861 tgcggatcaa ccgaagtttc ccaattgaga aattgatgga agctgtggat gagtatttag
    10921 agaaaacaaa ccgtcgaatc acgtttgaat atatcatgtt gaatcaagta aatgatagac
    10981 cagagcatgc gcaacaatta gcagatctat taaaagataa gaaaaaatta gcatatgtca
    11041 acttgattcc atataatcca gtcagtgaac atgatcaata ttctcgcagt ccaaaagctg
    11101 atgtattgag attttatgat gtattgaaga aaaacggcgt aaactgtgtg atacgtaaag
    11161 aacatggtac agatattgat gcagcttgcg gacaattgcg aagcaagcaa atgaaaaaaa
    11221 cagttgccaa ataatcgtat cctactcgtt ttttcaatta ccataaaagg agcagttttc
    11281 ttaattaagg aactgttcaa cttaaataag agaaaagatt ctatagcgaa agctataaag
    11341 ctttttttga caagaaaaac cctcatcaag caaagaaatg tcctcaattt gatgacagcc
    11401 tgcttgatgg gggttttagc aattatttaa ctgattttct tatatccttg ctggctttct
    11461 tgtgtagcat gataagtttc tacgtcaaga atggcctgtt taaatttttc tcgggtgatt
    11521 tcataaggca catgtttaat atcatttgtt gccatggctt tatctaagat tgcttctaaa
    11581 tcggtcgtga cattgagatt catgtcggtt aacgatactg gaagttggtt ctttttcata
    11641 aacacataga ttttatcaaa caaatcgaac tgctgatcca tcatcaataa ggtcagtaca
    11701 ccataactga cagatgctcc gtgaaggtat ccctccattt tttctagaac agtcgtaccg
    11761 taatagaatg agtgtgccat agcagaatta tagttattgt taactaaaac agaaaccaat
    11821 ccggtagtaa caatgatatc cgaaacgact tgttcaattg catatgaggg acgatcgtcg
    11881 gcactatctt tcaatgcttg cgtaccataa gtcaagagac gatcaatgca catttttccg
    11941 atttggattc ctaatctatc cgtgtagcct agatcatcgc cacgagcaga aaaagtagat
    12001 tcgacttctt tggataaagc atcgccaata cctgcccata agtatttatc aggtgcttcg
    12061 gcaataattg ctgtatcaat gaaggtgtgt acaggtggtt ttgaaggaaa gaagagtccg
    12121 tccattacgc cttcttcgtt atagatgaca cataccgcag tgacgggcga acagttcgaa
    12181 ccaatagtgg gaaaggtgaa gactggttta gctagttttt caccaatgac ttttacagta
    12241 tcgcaagcac ggccaccacc gactgcaaac aggacgtctg ctttttggac actttcatgc
    12301 tggatcaact gttcaatatt tccataagtt gaattacccc cgtaccagag actggcgaca
    12361 acctctattt cctgtgtcaa agctactttt attttgtttt ctgcctttga aagtgcagtc
    12421 ttccctccaa tcagcactac ttttgtccca tattctttga cgattccatt tgctttttca
    12481 tacgcatctg ttccaatggt ataatttggt aagaaaacac tttgactcat attcatttcc
    12541 ttctttcttc gttgaaacgg gttaaaattt taaagagtga tcgatctgac tgcggctgta
    12601 gatggagtag aggtgaacct aagacaggat aagtgatgaa taaggtggca tgaacacctt
    12661 gaaatcatca ataagtatcc taaaaacgaa caagtacaaa aacattgaaa acgacaataa
    12721 tgaatttttg ttcctcttag tatttctacc gattcccttt gcttttttgt aattatctaa
    12781 aaattctaaa aattaagatt attatatgaa aacaggtttt atttgtcaat tcataattgg
    12841 ttttttttaa agcaaaagat aatctatatc atgatgaaca aacagagttt tttcctccaa
    12901 ttgatggctt tcctgatctt tcctattttg aataaagtgt ttctgtataa ttttttattt
    12961 tataagtaag ataaataatg aaagaataga gatactgatt ggtagctaaa gatttttgag
    13021 cgagaacatt tcgttttttc aaaaggactg ttagaataag caagaacaag ggggaagacg
    13081 tatgataatc agtgaatttg accgtaataa tccagtattg aaagatcagc tttctgattt
    13141 actgagactg acttggccgg aagaatatgg agacagctcg gcagaagaag tagaagaaat
    13201 gatgaatcca gaacgaatcg cggtagcagc ggtagaccaa gatgagttag taggatttat
    13261 tggtgcaatc cctcaatacg gtatcacagg ttgggaattg catccattag ttgtagaaag
    13321 ctcccgacga aagaaccaaa taggtactcg attagtcaat tacttagaaa aagaagtagc
    13381 ttccagagga ggaatcacga tttatttagg tacggatgat ttagaccatg gaacaacgtt
    13441 aagtcaaacg gacctgtatg agcatacatt tgataaagtg gcttccatcc agaaccttcg
    13501 tgaacatccg tatgaattct atgaaaaatt aggttataaa atcgtaggtg tcttaccaaa
    13561 tgcaaatggc tgggacaaac cggatatttg gatggcaaaa acgattattc ctcgaccaaa
    13621 ttctcaataa taaaaagagg ttgtgacaga agtaatcagc ttcaagaaat aagaaggaat
    13681 ttacgaaaat tacttcttga atttttgtga aattccaact tatttccgaa gaagctactt
    13741 ttggaacacc gtgtac
//
LOCUS       DACGEU010000069        13716 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.069, whole genome shotgun sequence.
ACCESSION   DACGEU010000069 DACGEU010000000
VERSION     DACGEU010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13716)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13716)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13716
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.069"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            119..1546
                     /locus_tag="IXR40_002015"
     CDS             119..1546
                     /locus_tag="IXR40_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HAQ4361851.1"
                     /translation="MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSNLLHVCKTTLLN
                     DINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLSQNSLFLKTCLLYLEEDE
                     PDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPRFTEMERRLLLLNVSYRL
                     GGFNSWELPESFFERADRFIESVTENSGRFYDKENKEILSIGFAISFLRQQVCAVTID
                     SKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDF
                     QQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKF
                     YLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYI
                     VTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDA
                     VQYENIIPISINTIDRAIISAVQNK"
     gene            complement(1638..2003)
                     /locus_tag="IXR40_002016"
     CDS             complement(1638..2003)
                     /locus_tag="IXR40_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HAQ4361852.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(2000..2365)
                     /locus_tag="IXR40_002017"
     CDS             complement(2000..2365)
                     /locus_tag="IXR40_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HAQ4361853.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(2557..2805)
                     /locus_tag="IXR40_002018"
     CDS             complement(2557..2805)
                     /locus_tag="IXR40_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361854.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            2804..2932
                     /locus_tag="IXR40_002019"
     CDS             2804..2932
                     /locus_tag="IXR40_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HAQ4361855.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            2989..4683
                     /locus_tag="IXR40_002020"
     CDS             2989..4683
                     /locus_tag="IXR40_002020"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HAQ4361856.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKITNTLTQ
                     EEEYVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            4687..4806
                     /locus_tag="IXR40_002021"
                     /pseudo
     CDS             4687..4806
                     /locus_tag="IXR40_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349726.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
     gene            4888..5079
                     /locus_tag="IXR40_002022"
     CDS             4888..5079
                     /locus_tag="IXR40_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361857.1"
                     /translation="MDLLPQMQAFEHHLPRGYEKAALHQVIRAAKLKQLLMFLTWLDL
                     LPQMQAFEHRLPRGYEKGV"
     gene            5457..6590
                     /locus_tag="IXR40_002023"
     CDS             5457..6590
                     /locus_tag="IXR40_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HAQ4361858.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYA
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            6621..6941
                     /locus_tag="IXR40_002024"
     CDS             6621..6941
                     /locus_tag="IXR40_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361859.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(6970..7434)
                     /locus_tag="IXR40_002025"
     CDS             complement(6970..7434)
                     /locus_tag="IXR40_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4361860.1"
                     /translation="MVTYNWIKLREHPELVKQSANWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(7565..8818)
                     /locus_tag="IXR40_002026"
     CDS             complement(7565..8818)
                     /locus_tag="IXR40_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4361861.1"
                     /translation="MDKFVAFMEKHFIPVASKIGAQRHLVAIRDSFMVSMPLMILGAL
                     AVMINNLPIPGFQELMNSIFGGESWKGFGAAAWNGTFAILSVLIAFLLAYHLANGYRK
                     DGVSAGVISLGSFFALGGALGMSSNGLFIAIIVGIISTEIFVRLSGNEKLIIKMPDGV
                     PPAVAKAFASLLPAMITISAFALVAAIFAAFGVDDIVGSFYTVVQEPFMGLANSYPSA
                     LLLAFITPFLWFFGLHGANMVDPLMQTINAPAIEANVNAIAAGHSAPFIVNKPFFDSF
                     VNLGGTGATLGLLLAIYLVGRKNKPYMVVTNLSIAPGVFNINEPTMFGLPIVLNPIMF
                     IPFILTPMVLVSVAYFATSTGLVPAATVMPPWVTPPIIGGVLATKSIAGGVLAAVNLV
                     LSILIYLPFVKVATIQERRKEALDA"
     gene            complement(8847..9164)
                     /locus_tag="IXR40_002027"
     CDS             complement(8847..9164)
                     /locus_tag="IXR40_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAQ4361862.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            complement(9190..9510)
                     /locus_tag="IXR40_002028"
     CDS             complement(9190..9510)
                     /locus_tag="IXR40_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAQ4361863.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDVINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            complement(9974..11389)
                     /locus_tag="IXR40_002029"
     CDS             complement(9974..11389)
                     /locus_tag="IXR40_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAQ4361864.1"
                     /translation="MKITIPKNFILGAASSAWQTEGWKGKKEGQDSFIDSWYKNEHFV
                     WHNGYGPAVATNFMEQYQQDVDLMKSIHLTHYRTSINWARFFTDYENCIVDEEYAQHI
                     SEMIDSLIEADVEPMICLEHYEVPAFLLEKYDGWSSRKVVDFYAKYAQIAFDRYGDRV
                     KNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYHKVLATAKAVEIYRSGNYGGR
                     IGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPMVKGYYTEEFLELCQKQSIYF
                     DPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEETPFHPERYYEVFDLPGKKMN
                     NSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGREYEEQYMDEKGIVQDDYRIEF
                     IGQHLHYLIKATEEGANCEGYMLWAFTDCVSPMNAFKNRYGLVRIELNDERSRTLKKS
                     ASWYQTLIDKRELDLPDEIYK"
     gene            complement(11406..12722)
                     /locus_tag="IXR40_002030"
     CDS             complement(11406..12722)
                     /locus_tag="IXR40_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4361865.1"
                     /translation="MRGSGMSFMDKLANVLGNVATRINNLRYIMVIKNAFAALIPVII
                     TGAFGTLFSAMVFDSENGLAQISFLRFLEELKPIASAISYVTLSFLTIYAVFLIGIEL
                     AKLNKVDGVFPGIIAVMSYLSVNPTVYELVNENQTVIVENVLAKQYTDTKGLFLGMLV
                     SILSIELYCWLRKQKKLQLRMPDTVPTNVSASFSALFPTILTVSGIAAAGFIIKELTG
                     MYLYDIIYNVVQRPLEGVVQGLPGILLLMFIAQVFWVIGIHGNQMVKPIREPLLLAAI
                     AVNTEAFEAGKEVPNIITMPFWDMYMSMGGSGVTIGLLIAVLLVGKREDMKQITKLSL
                     APGIFNINEPVIFGMPIMLNPILAIPFILTPLITGTIGYFATALGFAAKAVVMVPWPM
                     PPIVNAYLATAGNIGAVITQLVCIIVSILIYLPFVKVANRVENDGI"
     gene            complement(12872..13570)
                     /locus_tag="IXR40_002031"
     CDS             complement(12872..13570)
                     /locus_tag="IXR40_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HAQ4361866.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNVA
                     LLHIIPIINESIALFNKNYDIQHLKIETIDIHTEIVQAIERRNALAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
BASE COUNT         4355 a         2786 c         2359 g         4216 t
ORIGIN      
        1 aaaacctttt ttaacggcat ttatatgctt tttcagaaat taactgatga tttcaaaaag
       61 aaaacatgtc ataatatttc ccatattgtg caaaaaaata caaggcggag gctctactat
      121 gattgaagaa tatattgaga aaaatatttt aagacagctg tttttatgtg ggcaattcta
      181 tgtaaataaa gaagtcaatc tagaaaagct ctccaatctc ctgcatgttt gcaaaaccac
      241 tttactcaat gatatcaata acataaaaaa agaatttgaa gaacagatcg cttatacaca
      301 tcgggaaaag gaccgttaca ctttatattt ttcagaacat atacctcgat gcaagatcat
      361 gcagcaattg tctcaaaatt cgttgttttt aaaaacttgt ctgctttatt tggaagaaga
      421 tgaacctgat tatcttcaat taactgaatg tgaattcatc tctgtcagca aagcttattc
      481 attaaaaaaa caagtattag cttattttaa tgactgcggg atcgaaatcg accgctactc
      541 ccctcgattc actgaaatgg aaagacgtct gctgcttctt aatgtgtcgt atcgtttagg
      601 cggttttaat tcttgggagc tacctgaatc gttttttgaa cgtgccgatc gtttcattga
      661 atccgtaacg gaaaatagtg gcagatttta tgataaagaa aataaagaaa tcttatcgat
      721 tggttttgct atcagtttcc tacgccagca agtgtgtgct gtgacaatag attcaaaatt
      781 tatcgaagaa atcaaaaaac gtcctattta caattatgtc gaatcagcat gggaaaacac
      841 tgatttccaa acctattata aaaaagaaga attcgccttt attttgacac tattcaatct
      901 ttgtaattat ggtttccatt cttatcagtt gattgcggaa gactttcaac agctacacca
      961 agtgtttatt gacaatactc ccgaaataaa agaactagtt gctacctttg aatctcactt
     1021 caatcaagaa ttattcggaa accaaccgtt cgaacgtgcg ctgattcatc tgatgcgttc
     1081 ggcttgggat aactatcaat tattcatgcc agaaaaattt tatcttttaa atgaggaaca
     1141 gacaaattta tataaagaag tccagacaat tttttccagc tggtccagcc agttacctta
     1201 tgatctacgg ttgaatccta attgcatgcg ggcttttgtg atcgaattga gcggaattct
     1261 ccgtctgaca aaagaacatc tgactatcta tatcgtcaca aattcggatg ttcattatct
     1321 gatttatcgg gaagccttgg aagctgtaac tactttcgat tttcaagttg caccaacaat
     1381 ttattcaagt atatctgata taaagaagta tgcgcagcag tcctcaaacc gggtattatg
     1441 tgaacgtaca ttatatacac cagatgcggt ccaatatgaa aatattattc ctatttcgat
     1501 caatacgatc gatcgagcta tcatttcagc tgtgcaaaac aaataagggg ctgtgacaaa
     1561 aatcatgtca cagcctctta tttgttgaag atgcccattt ctgtaacaat ctcttgatac
     1621 acgtcaggct cacaacctca cttattttgg acatctacgg gtccgatctc tttatttaaa
     1681 aaataagaaa tgatggttcg gataactacc aacgccgcta gttggaaaat atcctgcaag
     1741 gtaggtttga taatcgattc gatgatccca gctgaaacaa gaatttccaa acttagaagt
     1801 atatagcctc ccaacatctt tttaatagca ttgttctcgc tgactcggtc gctttgcact
     1861 tttgtatgga caaataaata tttcaaaaaa tccttgattg atagacaaac accccaaacc
     1921 aataaacaga tagcaaagat atcaagtccc agtacaagtt tttcgaaata tggaagaaga
     1981 aactgcatca actctgtcgt catcctacct ctcctcttct ttgtttttct ttgtcttcta
     2041 tttcctgatt caagaaataa gaaatgactg ttcgaatgat aataataagt gcaagcttca
     2101 aaatatctgt ccaagtcggc ttgataactg actcgatgat atcagcaacg actagtactt
     2161 ccaagcttaa caaaatataa cttgctagca gttttcttgt atctgcatta cgagtattac
     2221 gttctgcata gtttttcttg acatgagacc aatcaaaaag tttgaataga acaagaacga
     2281 tcccgacaat taagataccg atagaacaaa tatttaaaat agcaatgatc cattctagaa
     2341 attcaattaa atttgagcga aacatatacg ctacctactt tcttttaatt tgttcctatt
     2401 cttttattgt aaaagaaagt taccttgttc gtctatttaa aagttgttct aatgataacg
     2461 gttcgcttaa atttttcttt ttcactctcc catttttctc cctccatcca taaatcgtgg
     2521 aagtatccaa aacaacgtag caagttaaaa taaggcttag tccgtcatca gcttttcaaa
     2581 gaagcactgt ctcggtgctt tttttgtacc caaatttcta aaaatagaac catacacctc
     2641 ctcaaatctt ttcttcttac ctaccctatt tttatttaca ggaaaatcag acacttcttc
     2701 ttttttgtca aaatttcctt tttcttctcg tcctatcatt tggcattcta ataaaaacga
     2761 actatccttg gatatagaaa gagaaaacaa ggaggcgttt ttcatgagta aaaaattaat
     2821 caaagtcggc atcggtttag gtttgcttgc ccttggcgct gcatatctag gaaaaaagac
     2881 aggactattc gaagatgaca gtcatttata tgatgaattc gaatcaatct agcatcctat
     2941 ttagttgaat cactacggac atacttggaa gacattggag gaatcacaat gagaaaaagt
     3001 aaagcaataa tgattggtgc cggtattgcc aatatggcag cggctgttta tttgattcaa
     3061 gaaggcaaat ggaaagggga tcagatcacc ttttattcat tggatgatca cggttcaaat
     3121 gatggtgcac cgaccgacac tgtagtggat gaatattgga ataaaaacca tccattagaa
     3181 aaccaaaaag gctatattgc tcgaggcggt cgcatgctta attaccgtac ctatgtagat
     3241 ttgatggatc tgttaagtcg aataccttct gttactgagc cagggatgac tgctgaagaa
     3301 gatacgagag attttgatgc aaaacaccga acctttgaca aagcacgttt gatggaaggt
     3361 ggcaaaggaa tcattgatgg cggaaaactg ggattcaata ataaagaccg tattcttctg
     3421 actaaactga ttgctatgcc tgattcagaa gaagaaaaac tagacaatat cactatcgaa
     3481 gaatatttca aagatgatcc acactttttt gaaacaaact tctggtttat gtgggaaaca
     3541 acatttgctt tcagaacacg tagttctgct caagaattgc gtcgctatat gcatcaaatg
     3601 atttatgaat tcactcaaat cgaacatcta gtgggcgtca atcgaacacg ttacaatcaa
     3661 tacgaaagta ttatgcttcc tttgatcgag tacttgaaag aacaaggatg caaaatcatt
     3721 ttgaaccgcc gtgtcactga ctgggaattc aaagaaacac cgatgcaaga tgaaatcact
     3781 gtgactggtt tgaaaattac caatacactg actcaagaag aagaatacgt tgtggtcgat
     3841 gaagatacag cagttatttt cactaatggg tccattacag attcagctac tttaggagat
     3901 tacgaaacac cagctgtaga aaatatggat tatggtgcag cttctagtct ctggaaaaaa
     3961 gccagtgaac gtttctacaa cttgggaaat cctgacaaat tctttgctga tcgagatgca
     4021 agcgaatggg tcagctttac cctgacgacg aaaaaccatt tgttgttgaa tgaaatcacc
     4081 cgtatcacga ctcaagaacc aggaaatgcc ttgaattcat ttatttcaac cacaccgatc
     4141 acgccgttag gccaaaaaga tgtcaatatg tctatcgtcg tgcatcatca accgcatttt
     4201 acgtctcaga aaccaaatga aacagttatt tggggttatt tcctttatcc aagacgacgt
     4261 ggcgaatttg tggataaaca gtatattaaa atgaatggaa aagaaatgct agaagaactg
     4321 attggacaac tttcaaaagt agatcctgga ccagtgaata ttcgtgaaaa agaaacagaa
     4381 attttcgaca gcgtaataaa taatatccct gtctatatgc cttatgcttc cgcgttgttc
     4441 aataatcgtg ccaaaagcga tcgaccaaaa gtcattccta aacattcgac caatctggcc
     4501 tttacaggag aatttgtcga gcagccttat cagatgatct ttactgaaca aagtgctgta
     4561 cgttctggag aaatcgctgc tttccatttt gcgggtattc ctatgtcccg tcttgtcaaa
     4621 acaccgcgtt acgacaaaga tattcctact ctagctcgtg ccgcaaaaaa aatgtttgaa
     4681 taatcaagag gttgtgaaaa agctgccctg catcaagtaa taagaacaac caggctaaaa
     4741 cagcttctta tgtttttgat ttggttggac ttattaccgc agatgcaagc ttttgaacac
     4801 cgtttaccaa gaggttgtga aaaagctgcc ctgcatcaag taataagaac acccaagcta
     4861 aaactgcttc ttatgttttt gacttggttg gacttattac cgcagatgca agcttttgaa
     4921 caccatttac caagaggtta tgaaaaagct gccctgcatc aagtaataag agcagccaag
     4981 ctaaaacagc ttcttatgtt tttgacttgg ttagacttat taccgcagat gcaagctttt
     5041 gaacaccgtt taccaagagg ttatgaaaaa ggcgtttagt ttcgagtatg aagaaaaatt
     5101 ttgtgaaaat ggttcctcac gtttttgcat aaatttgact taataccgag aaactgatcc
     5161 cttctgtcat aacctctttt tatttatgtc tgtttctttt tgaaaacaac tattttttca
     5221 acgtttactc tcttgccaat ccaacatcat ctaacggata caactatttc aatgattacc
     5281 attacactaa aaaatcggaa acacacctct ccgaacacaa atacataaga ctatagaatg
     5341 tttcatttaa gaaaaaaagc gtttcattat caaaaaggta agatctcctt taaaatgaaa
     5401 ttatctgtag tactaataat gcagacaatt ttatgaatct gaaaggagca tctccaatga
     5461 aagcagtcac ttggcaagga aaacagaaaa tggaaatcag aaacgtagat gatccaaaaa
     5521 tattagaacc aacagatgca atcatccgta tcacagcaac agccatttgc ggctccgatc
     5581 tgcatcttta ccatcatggt gaagcagttt tggaaaaagg gtatgttgta ggacacgaac
     5641 caatgggaat cgttgaagaa gtgggatctc aagttcaaac attgaaaaaa gggcaacgtg
     5701 tggttatccc ttttaatatt agttgtggtc attgtcattt ctgcctgaat cacatggaaa
     5761 gccaatgtga tgaatcaaat ccagatcagt tatatggcgg gcttttcgga tttggcaagt
     5821 tgaacggtaa tcattggggt ggtcaagcgg aatatctaag agttccttat gcagactcta
     5881 cttcatttgt tgtaccagat aatgatcttc ctgatgaaaa agttttattt ctatcagata
     5941 ttttgcccac agcttattgg agcgttgaaa acgcaggagt aaaaaaaggc gatacagttg
     6001 tgattctagg ttctggtcca gtcggtctat tcgctcaaaa attcgctgtt atggctggag
     6061 cagagcgcgt aatcgcagta gatccagtac agcaccgtct agataaagcg gctaattaca
     6121 atggggttga aacttatttc ttagaagaca cggcacaagc tggaacagaa ttgtatgaac
     6181 tggctaaagg tggcgcagat gtcattatcg attgtgtagg aatggacgga ttagagcctg
     6241 tcaaagaaaa agcgaaaaat ttagtaagct tacaaagcgg cacaatctct ccattacaga
     6301 tggcatcgca agctgtcaaa aaatttggaa cagtccaagt aactggtgtt tatatgactc
     6361 cagcttcttc ttacccgctg caagaatttt ttatgcggga tatcgctgtc aagcatggac
     6421 aggcaccaat tatccatcta atgccaaaaa tttacgcaat gattgcagaa ggactattcg
     6481 atcctacaca aatcattact cattcgctgc cactatcaga agcagcacaa gcatatgaga
     6541 tctttgacaa aaaagaagat aaaaatataa aagttgtttt gaaaccttga attcagtaaa
     6601 aaatacaggt gattttcttt atgcccaaaa tcaaacgaaa tacccatgag atcgaaatag
     6661 gaaaagaaga agatatcgaa atacgaggac gtcgcttccg cttctatttc caaaatcgtt
     6721 acacattgat ctcactggct gtcgatttat taaccgggat tttctatatt tttggaagcc
     6781 ttgcttcctt aactaaaatc cccgatcgat atggcaccta tttttatttg gctggtgcta
     6841 ttttcttgac gattcgtcct attctcagaa tcgtaaggaa catttttatt tacgacgaaa
     6901 aaaaagcaat gaagagaaca agcaaaaaaa aagaggcatg agaatttttc aaatctcatg
     6961 cctctttttt caccctatcg tatcactttg atacagacga gcggtcgtcc cactttcttc
     7021 cttgaccatt gtcaaaaatg tccactcgta tcgttcataa aacgtggtat gatctgtaat
     7081 taagtaaagt ttttcgtacc caagttgatg catttctttt ctgatttccg ctaatatccg
     7141 cttggctatc ccctgcttac gcttttccgg ttcaacaaac agggcacaaa gatttggtgt
     7201 cagatcaggg cggttatgga agtcgttttc aatgacgccc gctcctccga cgatggtttc
     7261 tttttcatct aagaccacat accattgagg aatactttcc ttattagcga ttccagtacg
     7321 aatactttcc tcatacacaa cagcaggaac tccccatttt gatgaaaacc aattcgcgct
     7381 ttgttttact aattctgggt gttctcttaa tttgatccag ttatatgtaa ccaatgttta
     7441 aacctccgac taaaataaaa cgtttacaaa aattatacaa gtctttatga aaattagcaa
     7501 tgacaacaat agtgatgtaa aaaaaaaacg gaaaacaatc acttgttctc cgttttttga
     7561 ttaatcaagc atctaaagct tcttttcttc tttcttggat cgtagctacc ttgacgaacg
     7621 gtagatagat caaaatagaa agaaccaaat tgacagcggc tagtacacca cctgcaatac
     7681 tttttgttgc caatacaccg ccaataattg gtggagttac ccatggaggc ataacggtag
     7741 ctgctggcac taaacctgta gaagtcgcaa agtaagcaac actaactaag accattggtg
     7801 tcaaaataaa tggaatgaac atgatcgggt tcaacacgat aggtaaccca aacatcgttg
     7861 gttcattaat attgaagaca cctggcgcaa tcgacaagtt tgttacaacc atatatggtt
     7921 tgtttttacg tcctactaaa taaatagcta acagtaaacc taaagttgca cctgttcctc
     7981 ctaagttgac aaagctgtca aagaaaggtt tgttcacgat aaacggtgcg ctatgcccag
     8041 ctgcgattgc attaacgttt gcttcaatgg ctggcgcatt gattgtttgc atcaaaggat
     8101 cgaccatatt cgctccgtgt aaaccaaaga accataagaa tggtgtgata aatgcaagca
     8161 gtaaggcaga tggataagag tttgcaagtc ccataaatgg ttcttggacc actgtataga
     8221 aagaacctac gatatcatca acaccgaatg cagcaaaaat tgcagcaact aaagcaaacg
     8281 cagagatagt gatcattgct ggtagtaatg aagcaaatgc ttttgcaact gccggtggca
     8341 caccatcagg cattttgatg atcaattttt catttccgct taaacgtaca aagatttctg
     8401 ttgaaataat cccaacaata atagcaataa acaaaccgtt tgagctcata cctaatgctc
     8461 cgcctaaagc gaagaaagag cctaaagaaa tcacacctgc ggaaacaccg tcttttcggt
     8521 agccgttagc taaatgataa gcaagcaaga aagcaatcaa gacagaaaga atggcaaatg
     8581 taccgttcca agcagcagcc ccgaatcctt tccatgattc accaccaaaa attgagttca
     8641 tcaattcttg gaacccggga atcggtaagt tattgatcat tactgctaat gctcctaaga
     8701 tcattaacgg catactcacc ataaatgagt cccgaatcgc aactaaatgc cgttgtgcac
     8761 caatttttga tgctacaggt ataaaatgtt tctccataaa tgcaacaaat ttatccataa
     8821 atcttccctc ttttctttac tgtagattac gcgttcaatc gacgatacag atcaatgatc
     8881 tcttttgcta aatctgtaaa agctatagat gtcatcagat gatcttgact gtggaccgtc
     8941 aaaagcgtga cttcaacgtg atttccttgt gcttcttgtg tcagcatctc tgtttgagag
     9001 tgatgtgctt ggactaaaga ttcctctgca tctttgattt tttcatctgc taaagtgaaa
     9061 tcaccttttt tcgcagcagc aatcgcttcc attgcatcgc tttttgcatt tccgccaaac
     9121 atgatcagac ccatgatggc ttctagattt ttttgatctt ccatttattg tatcctccga
     9181 taatttttat tatttgttta ttagtttttc tgcttggtcg agtacttttt caccattcat
     9241 catgccatag tcagccatat tgattacatc taaaggaatg cctttaggtg ctagcttttc
     9301 agcaaattga ttttgcataa agcgtacttg cggtcctaaa agtaaaacgt ctacattttt
     9361 agattctagt tgattatccg catctgaagc agatacagca aagatgtctg cttccattcc
     9421 ttttgcttct gctgcctttt gcatttttgt gactaggaga cttgtactca ttccagctga
     9481 acatacaagc atgattgttt tcttttccat tttaaacacg ttcctttcta tacttacact
     9541 tgtatataag caagtagcgt gccaacttta aaagcgcttt aaaaagttga tatcatcaca
     9601 tttaaggtct ataccaagtt gcatacacac taaaaaagaa agcgcacact aaacacacaa
     9661 attaattttt attacctttt ttcttttaac gtgcacaaaa aaagttgtga cacaaaactt
     9721 gtcacaactt ttttcaaata aacggtattc aaaagcttgc atctgcggta ataagtccaa
     9781 ccaagttaaa aacataagat gttgttttta ctttgctatt cttattactt gatgcaggac
     9841 agctttttca caacctctca ataaacggtg ttcaatcagc tgaccctggg tattagctca
     9901 aaacgctgga ttcacaacct cttttatttc aaataaccag taaatacaat gaacatctac
     9961 aaaaaacttc tatttattta tagatttcgt caggcaaatc caattctctc ttatcaatca
    10021 aagtctgata ccacgaagca gattttttca atgttctgct tcgttcatcg ttcaattcga
    10081 ttcgaactaa tccatatcga ttcttaaatg cattcattgg tgacacacag tcagtgaatg
    10141 cccataacat atagccttcg caatttgcgc cttcttctgt tgctttgatc aagtaatgca
    10201 aatgctgtcc gataaattcg atacggtaat catcttgcac gattcctttc tcatccatat
    10261 actgttcttc atattctctt cccataccgt tttctgttat cagccaaggg atattatgat
    10321 aattttcttt tagatacatg gctatatcat acatgatttt cggatagatt tcccatcccc
    10381 tggaattatt cattttcttc ccaggtaaat caaagacttc ataatatcgt tcaggatgga
    10441 aaggtgtctc ttcattccat tgataacgag gggcgcgaac gcgtttagga taatattgat
    10501 tgattccaag gaaatctact gtatgatgct gaatcgtttc taaatcctct gttgcaggat
    10561 cgaaataaat cgattgtttt tgacacaact ccaggaactc ttctgtgtag tatcctttta
    10621 ccatcggatc aaaaaatact cgattataaa acaaatcata catataagca gctttttggt
    10681 cttctggaga attggatcga gcatagacca tttcaggatt taaaatacag ccaatccttc
    10741 caccataatt tccgctgcgg taaatctcta ctgctttagc cgttgctaaa actttatgat
    10801 aattccacat catccacttt tttgtgtttt gttcatgcgg ccagcgaaca gcatccaaat
    10861 agcaacgcgt ttggggaacg attggttcgt tgaatgtaaa ccagtttttt accctatcac
    10921 cgtaacgatc aaaggcaatt tgagcatact tagcataaaa atcaactact tttcttgaag
    10981 accagccatc atatttttcc aaaagaaaag ctgggacttc ataatgttcc aaacaaatca
    11041 tcggttctac gtctgcttcg atcaaagagt cgatcatttc acttatatgc tgagcatatt
    11101 cttcatctac tatacagttc tcataatcag taaaaaaacg agcccaattg atagaagtcc
    11161 gataatgtgt cagatggatg gatttcatca gatccacatc ctgctggtat tgttccataa
    11221 aattagttgc tacggctggg ccatacccat tatgccaaac aaaatgttca tttttatacc
    11281 agctatctat aaacgaatcc tgtccttctt tttttccttt ccaaccttcc gtttgccaag
    11341 cagaagatgc agcaccaaga ataaaatttt ttggaatagt aattttcatg atttcctcct
    11401 gttttttaga tcccatcatt ttccacacga tttgctactt ttacaaatgg cagatagatc
    11461 aaaatagaaa caataataca aacaagttgc gtaataactg caccgatatt tcctgctgtt
    11521 gccagataag cattgacgat cggcggcatt ggccaaggga ccattacaac tgctttcgcc
    11581 gcaaatccta aagcggttgc aaaataacca atcgttccag tgataagagg cgttaagata
    11641 aacggaatag ctaaaattgg attcagcatg atcggcatac caaaaataac tggttcattg
    11701 atgttgaaga tcccaggagc aagggataac ttggtgattt gtttcatatc ttcccgtttt
    11761 ccaactaaca atactgcaat cagtaaaccg atcgtgactc cagacccgcc catactcata
    11821 tacatatccc aaaatggcat agtaataatg ttcggtactt cttttccagc ttcaaaagct
    11881 tccgtattta cagcaattgc cgctaaaagc aacggttccc gtatcggctt caccatttga
    11941 tttccatgga taccaatcac ccaaaagact tgcgcaataa acatcaatag caaaataccc
    12001 ggtaaccctt gtacgacacc ttctaatggg cgttgtacga cattgtaaat gatatcataa
    12061 aggtacattc ctgtaagttc tttgatgata aatcccgcag ccgcgatacc cgatacagtc
    12121 agaatcgtcg ggaataaagc agaaaaacta gcagaaacat tcgttggcac ggtatcaggc
    12181 attctcagct gtagtttctt ctgtttcctc aaccagcaat aaagttcaat agaaaggatg
    12241 gagaccaaca ttcccaaaaa taaccctttc gtatctgtat attgtttagc caatacgttt
    12301 tctactataa cagtctgatt ttcattcact aattcataaa cagttggatt aacagataaa
    12361 taagacatca ctgcgatgat accagggaat acaccatcca ctttattcag cttggctaat
    12421 tcgatcccta tcagaaaaac agcatagatg gtcaagaaac ttagtgtgac atagctgatg
    12481 gcagatgcga taggctttaa ttcttctaaa aaacgcaaga aacttatctg tgctaagcca
    12541 ttttccgagt caaagaccat tgctgaaaac aatgtgccaa aagcacccgt aataattacc
    12601 ggaatcaatg cagcaaatgc gttttttatc accatgatat accttaaatt attgattctc
    12661 gttgccacgt tccctaaaac attggctaat ttatccataa aactcattcc agatcccctc
    12721 attcctgctt cttctccttg acgtcatctc tttttgtcta ttagtcagcg cttacatttc
    12781 gatgaacaga aactatttac tcctcttttt taccaaatat aaaacaaaaa ttcatctgat
    12841 gtatttatca taaaatacat cagatgaact gtcaattagt ttctttttct cctattattt
    12901 tctgtaattc tctccgattt attgccatat ggacagtcat tgcatcaaac gcagcaagtg
    12961 cattccgcct ttcgatggcc tgaacgatct ctgtatgaat atcgatcgtc tcgattttca
    13021 gatgctggat atcataattt ttattaaaca aagcaattga ttcattaatg attgggataa
    13081 tatgcagcaa ggctacgttt ccgctagctt ctgcaatcat cgtatgaaaa tcgatgtcta
    13141 attgaacatg ttcttgtgtg ccttctcgaa aagaagtttc aatcttttgc gttaattttt
    13201 tcatttggac gatttgattc ttcgttgcat attccgctgc caaacctgcc atcttaggct
    13261 ccaataaata tctcagttca aataagtctc gtatcatccg atcctgatct tcaatcaaag
    13321 aaaaaccgag tgggtcattg gcaatccctc gcttatcact gacaaatgtc cccgctcctt
    13381 gccgaacttc aaggatattc ctggaagcta gagcccgcac agcttctcgc accgtgcttc
    13441 gccccacctc taaataatcg gacaattcat attcattcgg cagtttatct cctacttgca
    13501 actgcatttc ctttaaatat ctaaggatct tgtcagtagt tacttctact agggttttat
    13561 tttcttccaa accacatacc tccttttcat ctgatgtatt ttttcgtaat tattataaca
    13621 cgtttgaatc atctgatgat tttttgtata caaaattgat taatccgttc atagacatac
    13681 aaacgaagaa gatatttacc ataaaaaaga ctagga
//
LOCUS       DACGEU010000070        13699 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.070, whole genome shotgun sequence.
ACCESSION   DACGEU010000070 DACGEU010000000
VERSION     DACGEU010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13699)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13699)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13699
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.070"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            75..317
                     /gene="yaaA"
                     /locus_tag="IXR40_002032"
     CDS             75..317
                     /gene="yaaA"
                     /locus_tag="IXR40_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HAQ4361867.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            304..1428
                     /gene="recF"
                     /locus_tag="IXR40_002033"
     CDS             304..1428
                     /gene="recF"
                     /locus_tag="IXR40_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HAQ4361868.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQIRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDSRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            1425..3371
                     /gene="gyrB"
                     /locus_tag="IXR40_002034"
     CDS             1425..3371
                     /gene="gyrB"
                     /locus_tag="IXR40_002034"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HAQ4361869.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            3391..5862
                     /gene="gyrA"
                     /locus_tag="IXR40_002035"
     CDS             3391..5862
                     /gene="gyrA"
                     /locus_tag="IXR40_002035"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HAQ4361870.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDYAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKEDQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            6098..6397
                     /locus_tag="IXR40_002036"
     CDS             6098..6397
                     /locus_tag="IXR40_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HAQ4361871.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            6447..6959
                     /gene="ssb"
                     /locus_tag="IXR40_002037"
     CDS             6447..6959
                     /gene="ssb"
                     /locus_tag="IXR40_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HAQ4361872.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            6985..7221
                     /gene="rpsR"
                     /locus_tag="IXR40_002038"
     CDS             6985..7221
                     /gene="rpsR"
                     /locus_tag="IXR40_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HAQ4361873.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            7364..9337
                     /locus_tag="IXR40_002039"
     CDS             7364..9337
                     /locus_tag="IXR40_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HAQ4361874.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            9343..9795
                     /gene="rplI"
                     /locus_tag="IXR40_002040"
     CDS             9343..9795
                     /gene="rplI"
                     /locus_tag="IXR40_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HAQ4361875.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            10069..11436
                     /gene="dnaB"
                     /locus_tag="IXR40_002041"
     CDS             10069..11436
                     /gene="dnaB"
                     /locus_tag="IXR40_002041"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HAQ4361876.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            12216..13508
                     /locus_tag="IXR40_002042"
     CDS             12216..13508
                     /locus_tag="IXR40_002042"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HAQ4361877.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
BASE COUNT         4562 a         2473 c         3018 g         3646 t
ORIGIN      
        1 ggataaattt gttttattgc gaaaaaaaag gtataataga gtatactttt aataatgaaa
       61 atgagggatg ggcattgaaa caacaagtca ttctaaatac ggaattcatg acgttgggcc
      121 aaatgttgaa agaagtcaca gttatcggta gtggcggaca agcaaaatgg tatttggcag
      181 aaaacactgt gttagtcgat ggcgaaccag aaaatcgtcg tggacgcaaa ctttatcccg
      241 gcatgatggt tgaagttcca gaagtaggaa ctttttttat ggtaaaaaaa ggaaacgacg
      301 ataatgaggc tgaataagct gtatttaaaa aattatcgaa attacgaaga gctgaacatc
      361 gaattttcca agaacctcgt catcttttta ggagaaaatg cgcaaggaaa aacgaatctt
      421 ttggaaagta tctacgtatt agctatgacg cgaagtcatc ggacaagtag tgagcaggaa
      481 ttgattggct ggactgacga tcaggcgatg attcaaggag agatcacaaa aggttcatcc
      541 actcttccat tagaaatctt attatctaaa aaaggccgaa aaaccaagat caaccatatc
      601 gaacaaaaaa agttaagtac ttacgtggga caaatgaatg tcattttatt tgcaccagaa
      661 gatctttctt tagtaaaagg cagcccgcag atcaggcgga agtttttaga tatggaatta
      721 ggccagatca atccaatcta tctttatgat cttgtccaat accaagcaat tttgaaacaa
      781 agaaaccagt atttaaagca attgaatgaa aaaaaacaaa ctgatttgct ttatttggat
      841 attttgtccg aacaactagc agcgtttggc agcaaagtat tgaaagcaag agcacagttc
      901 gtcaagcgat tggagttttg ggctaattct ttgcatcagc aaatcaccca tcaaaaagag
      961 cagctggaaa tcgagtatct caccgcagtc gattctttag aaacacatac gcaagagcaa
     1021 atccaagaac aatttctcgc acttttgaac caaaataaaa agaaagacct ttttcgggga
     1081 acaacgacag ttggtcctca tcgtgacgat ctttcctttt ttattaatca gaaaaatgtg
     1141 cagacttatg gatcgcaagg acagcaaaga acaactgcac taagtgtcaa attagcagaa
     1201 atcgatttga ttaaagaaga gacgggggaa tatccaatcc ttttgttaga tgatgtgatg
     1261 agcgagctgg atgatagtcg tcaactccat ctgctagaaa caatcgaagg aaaagttcaa
     1321 acgttcttaa caacaacgac acttgaccat gtaaaaaata aaatgactgt tgaacctgag
     1381 attttttatg ttcaacaagg gaaactaaaa ggagaagaaa ctgaatgaca gaagaaagaa
     1441 gtttagtaga acgcgctaaa gagtatgatg ccagtcagat tcaagtactt gaaggacttg
     1501 aagccgttcg taaacgacct ggcatgtata tcggttcgac tagttctgag ggtctgcatc
     1561 accttgtttg ggaaattgtc gataattcga tcgatgaagt attagcaggt tttgcaacga
     1621 aaatccatgt gattattgaa aaagacaaca gtatcaccgt tattgacgac ggtcggggga
     1681 tacctgtaga tatccaggca aaaactggac gtcctgcagt tgaaacggtc tttactgttt
     1741 tacatgctgg aggaaaattc ggcggtggtg ggtacaaagt ttctggtgga cttcacggag
     1801 taggatcttc tgttgttaac gcgctttcta cacagcttga tgtcaaagta tacaaagaag
     1861 gaaatgtgta ctatcaagaa tatcgtcgtg gagctgtagt ggacgactta aagattatcg
     1921 aacaaacgga tcgccatgga acaacggttc actttacgcc agaccctgaa atttttacag
     1981 agacaactga gtttgatttt tcaaaattgg ctacccggat ccgtgaactt gctttcttga
     2041 accgcgggat gcgtatatcg attgaagaca aacgagaaga agaaccagtc atcaatgaat
     2101 accattatga cggcgggatt aaaagttatg tcgaatactt gaatgcaaac aaaaccgtga
     2161 tttttccaga acctgtatat ttggaaggtg aacagcaaga tatcgcagtt gaagtctcta
     2221 tgcaatatac agacggctac cattccaata tcatgagttt tgccaacaat atccatacgt
     2281 atgaaggcgg aacacatgaa tcaggattca agactgcttt aactcgtgtg ataaatgatt
     2341 atgcccgaaa acaaaagctg atgaaagaaa atgacgacaa cttgaccggt gaagacgtgc
     2401 gagaaggatt gacagctgtt atttctatca agcatcctga ccctcaattc gaaggacaaa
     2461 caaaaacaaa attgggcaat tccgaagtac ggacagtcac tgatcggtta tttagcgaac
     2521 atttcatgaa attcttgctg gaaaacccaa gtgtgggccg tcaaattgtt gaaaaaggat
     2581 tactagcttc cagagctcgt ctagcagcga aacgtgcgcg tgaagtaacg agacgtaaag
     2641 gtgctttaga gattagtaat ctgccaggaa aattagcgga ctgctctagc aacgatcctg
     2701 aaaaatgcga attgttcatc gtcgaaggag attcggccgg cggatcagct aagcaaggtc
     2761 gtaatcgaga gtttcaagcc atcttgccta ttcgtgggaa aatcttgaat gttgaaaaag
     2821 caagcatgga caagatcttg gcaaatgaag agatccggtc tttatttact gctatgggta
     2881 cagggtttgg agaagatttt gatgtatcga aagctcgcta ccacaaatta gttatcatga
     2941 ctgatgccga tgtcgacggc gcgcatatcc gtacattgct gctgactctt ttttatcgtt
     3001 acatgcgtcc tattgttgaa gctggatacg tctatattgc tcagccacct ttatacgggg
     3061 taaaacaagg gaagaatatt acgtatgtac aaccaggaaa aaatgcagaa gaagagttga
     3121 aacaagtcgt tgcttcactt cctgcctcac caaaaccaag cgttcagcgt tataaaggac
     3181 ttggagaaat ggatgatcat caactatggg aaacaactat ggacccaagc aatcggatga
     3241 tggcccgcgt cagtgtggac gatgctattg cagcagatca gatatttgaa atgttgatgg
     3301 gggatcgagt agaaccccgt cgtgcattca tcgaggaaaa tgcacactat gtgaagaact
     3361 tagatattta atcatgaagg aggaaaaaga atgagtgaag aaatcagaga aaacatccat
     3421 gatgtcaatc taaccagcga aatgaaagac tccttcatcg attatgcgat gagtgttatt
     3481 gtcgcacgtg cacttcctga tgtcagagat ggtctgaaac ccgttcatcg ccgtatttta
     3541 tacggcatga acgaattagg tgtaacaccg gataaagccc ataaaaaatc tgccagaatc
     3601 gtcggagatg tcatgggtaa ataccatcct catggagact atgcgatcta tgagtcaatg
     3661 gtacggatgg cacagccatt cagctaccgt tatatgctag tggatggtca tggaaacttt
     3721 ggttctgttg acggtgacgg tgccgccgct atgcgttata ccgaagcacg gatgagcaaa
     3781 atcgctacag aaatgctgcg tgatatcaat aagaacactg ttgatttcca aagcaactat
     3841 gatgatacag aaaaagaacc agttgtacta cctgctcgct tcccgaatct tttagtgaac
     3901 ggaacaacgg ggatcgccgt aggtatggcc acgaatatcc cacctcataa cttgtctgag
     3961 gtagtagcgg ctatcgattt gctgatggat aatcctgatg tgacgaccaa tgaattgatg
     4021 gaagtattac ctggaccaga ttttccaaca ggtggtttgg ttatgggaaa atcaggaatc
     4081 cgaagagcgt atgaaacagg taagggttct attaccgtac gtgcaaaagt tgagattact
     4141 gagatgccaa atggtaaaga acggatcatc gtgacagaat tgccttatat ggtcaataaa
     4201 gcaaaattga tcgaacggat ttctgaactg cacagagaca agcgtatcga agggatcaca
     4261 gatttgcggg acgaatcttc ccgtgaaggt atgcggatcg tcattgacat ccgtcgtgac
     4321 gccagcgcat ctgttatctt gaataactta tataaattga catccttgca aaattcattt
     4381 ggattcaata tgttggcgat cgaaaaaggt gtgccgaaag ttttgagctt gaaacaaatt
     4441 cttgaaaact atatcgaaca tcagcgcgaa gtcatcacaa gacggacagt ctttgaaaaa
     4501 gaaaaagcag aagcaagggc acacatttta gaaggtttgc gtattgcttt ggatcatatc
     4561 gatgaaatca ttgcgattat ccgcgggtct aaatcagatg acgaagcaaa agcgacgatg
     4621 atcgaacggt tcgatttatc cgatcgccag tctcaagcta ttttagatat gcgtttacgc
     4681 cgattgaccg gtttggaacg ggaaaaaatc gaaaatgaat accaagaact cttaaaactg
     4741 attgaagatt taactgacat tctggcaaga ccagaacgtg ttacagaaat catcaagaat
     4801 gaattagcag acttgaatca acgatttggt gataaacgac gcacagaatt actagtcggt
     4861 gaggtcttaa gtctggaaga tgaagattta atcgaagaag aagaaatcgt tattacattg
     4921 acaaacaatg gttacatcaa acgtttggca aataatgaat tcagagctca acgaaggggt
     4981 ggacgtggtg tccaaggaat gggtatccac aatgacgact tcgtcaaaaa tctggtttct
     5041 tgttctaccc atgatacatt gttattcttt acgaataacg gaaaagtgta tcgggcaaaa
     5101 ggatacgaaa ttccagaata cgggcgcaca gccaaaggaa taccaattat caatttacta
     5161 ggtatcgatt cgagtgaaag catccaggca atcattgcgg tgacgggaga agcagaagaa
     5221 ggccactatc tcttctttac gacgcgtcaa ggtacagtaa aacgtacttc tgtcactgct
     5281 tttgctaaca tccgaagtaa tggtctgatc gcaattggtt tgaaagaaga cgatgagctc
     5341 gtcaatgtgc tactgacaga tggtcaatct aatatcatta ttggaacaca taacggctac
     5401 tctgtcactt tcaaagaaga agcagtccgc gatatgggac gtacagcttc cggggttaga
     5461 ggaatacgcc tgcgtgagga agattatgtc gttggggcag ccttaatgaa ggaagatcaa
     5521 gaagtattag tgatcacaga aaaaggttac ggaaaacgga caaaagtatc ggaatatcca
     5581 gtgaaaggcc gcggaggtaa agggatcaaa acggcgaaca tcactgaaaa aaatggtcca
     5641 ctagctggat tgaccactgt ttctggagat gaagacatca tgctgattac agataaaggt
     5701 gtcattatcc gtttcaacgt atcgactgtt tctcaaactg gacgttcaac attaggcgta
     5761 cgtttgatga agatggaagc tgatacgaaa gttgtcacga tggcagcagt cgaaccagaa
     5821 gctgcagaac aaacagttga agaacaagga tcagaagaat agccatcaag actaattgtg
     5881 taagctagca agaatgaccg attaaaaaat ctggttattc ctgctggctt ttttgattag
     5941 ttgaatttct cttaaaatat tcgaaactgt tcattctgta ttgcttttga ccaaaataga
     6001 gtgtataatc agagcttgtg agtagtctaa ttaattagat aactctcctt gctcttagga
     6061 acctaagagc cgaaagtcca cagggaggtg aatatcaatg gaaaacacga aatatgaaat
     6121 catgtacatt attcgtccaa acattgatga agaagcaaaa actgctttaa tcgaacgttt
     6181 cgatgcaatc ttgaaagata acggagcaga agttatcgaa tcaaaagatt gggaaaaacg
     6241 ccgtttcgct tatgaaatga acggttaccg tgaaggtatc tatcacatcg ttaaagtatc
     6301 ttctccatca tcagcaaatg ctgtcaatga atttgaccgt cttgctaaaa tcaacgacga
     6361 tatcattcgt cacatgattg ttaaagaaga agcttaattg ttgtttcatg tgaaacaata
     6421 gaaaacgatg agaggagatg actattttga ttaataatgt tgtattagtt ggacgtctga
     6481 cgaaagatcc agatttgcgt tacacagcaa gtggtacggc agtcgcaaca tttactttgg
     6541 ctgtgaatcg taattttaca aaccaaagcg gcaatcgcga ggctgatttt atcaactgtg
     6601 tgatttggcg caaatcagca gaaactttag caaactatgc tcgtaaagga acacttttag
     6661 gtgttactgg acgtatccaa actcgttctt atgataatca gcaaggacaa cgtgtatacg
     6721 tgacagaagt agtagctgac aacttccaat tgctggaaag tcgttctgca tctgaaaatc
     6781 gccaacaaag cggcggattc caaagttctg gtcaatcagc tggcggattt ggcggaaaca
     6841 ataactctaa tcaaacatct caatcatcca acggtatgcc tgatttcgac cgtgatactt
     6901 ctgacccatt cggctcaagt tcaacgatcg acatttcaga cgatgattta ccattctaaa
     6961 cgaatttgat aggagggaaa tagaatggca caacaaagaa gaggcggacg taaacgtcgt
     7021 aaagtagact acattgctgc taaccatatt gaatatatcg attataaaga tatcgaatta
     7081 ctaaaaagat ttatttcaga acgcggtaaa atcttgccac gtcgtgtaac tggtacaggc
     7141 gctaaaaacc aacgtaaaat tactgttgca atcaaacgcg ctcgtatcat gggcttgcta
     7201 cctttcgtta gcgaagacta ataaatccta ggaattgaat gactgatcct tttgatcagc
     7261 tattcaattc ctttttttct gtaaaaataa cctctattcg tttagtcgct cgaatgacga
     7321 aagttatggt aaaatcaaat tagtcatata tgggaggaaa attatggaaa ataaaaacaa
     7381 tcatttatcc ccgaaacctc tcttccttat cctgtttata ttaatcgaag tattggtagt
     7441 cttaatttta ccatttcgtt ttgttagcgc ttcggtcatt ctattgatga atttatgggg
     7501 tgttcgctat tggttgaaaa tgaaacgttg gcttatttta aataaacgtg aaaaaatcca
     7561 gcaggcttcg actgtagctg aaaccaatct agcttatgtc tcagaagtca tgcctgtagg
     7621 agtgattgct tatcagccat caagccaaaa aatcgaatgg ctcaatccat tagcattgaa
     7681 aatcaaagat caaagtggat taacagagga agaattgcta gatacttttt ttactgcaaa
     7741 agaaaaaaag aaaaaccaag tctatctagc agataaaaca tttcagtttg atatggatac
     7801 agtaaagggt gttgtttatt ttaatgatat tacccaaaac cagttgttaa aactccatca
     7861 gacgaacagt cagccggtga ttggtatttt atctattgat aactatgcag atgccattga
     7921 taaattggat gacaaagaga tttcttattt gaactctttc gtcactacac tagtttctga
     7981 ctggatgaat gaataccatg tctttttcaa aagaatcaac gcagaacggt ttttcttcgt
     8041 agcacagatg atcgatctga aaaagatgat ggataaaaaa tttgatttgc tggatcgctt
     8101 tcgagcagaa gctgaaaaac agagctcgcc tatcaccctt agtatgggga ttgcttatgg
     8161 ctcaagaacc ctcgatgaaa tcggtggaga agctcagaat aatttagatg ttgctttagt
     8221 ccgtggaggc gaccaagttg tcgtgaaaga ggtaaaagaa ggagcaaaac ctgtttatta
     8281 tggggggaaa tctgctaaga atgtcaaacg cacgcgtgtt cgttctcgag cgatgagtac
     8341 cgctttgcgt cggatttttg atgaaacagg cgatgtgttt atcatggggc acaagtttcc
     8401 ggatatggat gctttaggct ctgcttttgg tgtcagttgt ctggcacgct tcaaccagaa
     8461 aaaagcttac atcgttatca acgagaacga gatcattcca gatgtagaac ggtgtcttga
     8521 agaaatccat aagcatcctg aattagaaat gcaactaatc tctccagaac gtgccataga
     8581 gctgaaaaaa gaagaggacc tcctcgtgat ggtggattac cataaacctt ctctatcgat
     8641 ctctcagggc ctatatgagc aatttgataa gattgtgatc attgatcacc atcgtcgtgg
     8701 ggaagagttt ccaagtaaac ctctgctgac ttatatcgaa tcttcagctt cttcagcttc
     8761 agagctagtt tctgagctga tccaatacca aagcagcaaa acaaatcgct tagatcgttt
     8821 tgaggccaca ttattgcttg cagggatggt tgtagataca aatagtttca atgtccgtac
     8881 aactgcacga acttttgacg ttgccagcta tttaaggtct tgtggagcag acgcatcctt
     8941 agtacaatat ttattgagct cggatttagc gacatacttg gagatcagca atttgattgc
     9001 tggaagcgac tatgtgactt ctgatattgt tgtggcggca gggacagacg aaaaagagta
     9061 taatagtgtt atagcagcaa aaacagcaga tacattgctt tcgatgatca atatcaatgc
     9121 agctttcgtc attacaaagc ggacagacgg cttgattggg atcagtgcca gaagtaccgg
     9181 cacgatcaac gtccaaatca tcatggaatc cttaggtggc ggaggacact tcacaaacgc
     9241 agctactcaa ctggaaaata cgacagttga ggaaacaaaa cagaagctat ttgctgcaat
     9301 caaagaaaat atgaatcaaa tatatgataa ggagtaatcc aaatgaaagt aattttttta
     9361 caagatgtaa aaggaaaagg taaaaaaggg gacatcaaag aagttccagc aggttatgca
     9421 caaaattatc taatcaaaaa taacttggca aaagaagcaa cgaaaagcag tatcagtcag
     9481 ttagcaggac aaaagaaagc acaagaaaaa cacgaagctg aaatcttgga agaagctaaa
     9541 aagttaaaag aattcttgga aaaagaagat actgtagtcg aattgaaggc gaaagcaggg
     9601 gaagacagcc gtttgtttgg ttcgatccct tcaaaacaaa ttgctgaagg gttaaacaaa
     9661 caatacaaaa tcaaattaga taaacgaaaa atcgaattag aaaatccgat ccgttcacta
     9721 ggctacacaa acgtacctgt taagcttcat catgaggtga cggctacgat caaagttcat
     9781 gtcgtacaag aataacaaat cttgatagcg atgttcagct ggtaagtata accagaagga
     9841 aaaaagacaa accgaaattt atctgagaaa acagctgcag caatgaaagc aaaagctgca
     9901 aatcgatttc agattgattt cggtttcttt tttgggaaca gcaaaatagc ataaagaaaa
     9961 cgagtataat aaaagagaac tattttttta ttacactttc ggtacgaatg atgacttttc
    10021 tctcattttc ttgtaaaatg aagcaattga agacaaggag cgatacgtat gaatgaagtg
    10081 tggcaggatc gaatcccacc gcaaaatatt gaagctgaac aagcggtttt aggctctgtt
    10141 tttcttgacg cagaaacgat cattgatgcc atggagtaca tagagccaaa agacttttat
    10201 cgtcgtggcc atcaaattat ttttgagaca atgatcgagt taaatgatcg taatgaagcg
    10261 attgacgtgg ttactgtcaa agaccggctg gaacaagcca atttgttaga agatgccggt
    10321 ggtttaagtt atctctcaga cttggcatta gcagttccga cagcagcaaa tatcgtctac
    10381 tatgcgaaaa tcgttgaaga aaaatcattg ctgcgtacat tgatccagac agcaacagga
    10441 atcgttacga aaggattcga gcaaggagaa gaagttcaaa caattttaga tgatgccgaa
    10501 cgcagtatct tggaggtttc ggaaaaaaga aatcgaagcg gctttttatc tattgctgaa
    10561 gtactgaact ccacgattga aaatatcgat cgactagctc aaaacaatga agaaatcaca
    10621 ggtctaccaa ctggctatca aggtctggat aaaatgacag caggtttcca gcccgaagaa
    10681 ctaatcattc ttgctgcacg tccagcggta ggtaaaacag cgtttgcatt gaatattgct
    10741 caaaatgtag gaacaaaaac agatcgttct gttgcgatat ttagtttgga aatgggggca
    10801 gaatctcttg taaatcggat gctttgtgca gaaggttcga ttgaggccag ccatttacgt
    10861 acaggtcagc tttcggaaga agaatggtcg aatctgatcg ttgcgatggg gagtctttct
    10921 cgagcaaata tttttatcga tgatacacca gggatcaaaa tctctgaaat ccgtgcgaaa
    10981 tgtcggaaac tagcgcaaga aaaaggcaat ctaggcttga tattgatcga ttatttgcag
    11041 ttgattgaag gtaacggtaa agagaaccgt caacaagaag tatcagatat ctctcgccaa
    11101 ctgaaaaaac tggcgaaaga gctgaaagta cctgtcattg ctctttcaca gttatctcgt
    11161 ggagtagaac agcgacaaga caaacgacca gtgctaagtg atattcgtga atccggatca
    11221 attgaacaag atgcggacat cgtagccttc ttgtatcgag atgattatta tgaaagagaa
    11281 ggcggagatg acgatgatgg aaacgagcca aaaaatgaca acgtcatcga agtcatcatc
    11341 gagaagaacc gaagcggtgc acgaggaaca gttgaactac tgtttatcaa agaatacaat
    11401 aagttttcgt cgctttcgcc aagagaagaa ttttaaagaa gaggttgtga gccttgagca
    11461 atcccgagag ctctcgtaag aagatgcaag gagtaaccgc aggaacgact agagtactta
    11521 atttaaacag atctccaaag ggattgtgac aaaagtcttg tcacagtccc tttttccgaa
    11581 taaacggtgt tcaatcagct gacccttggt attagctcag caaacgtcaa aatatgagga
    11641 actattttga cgtttgtttc tctaatactc aggtcaaaac gctgatctta cgacctcttt
    11701 tccttaaacg gtgttctcct gccaactcct cggtcacaag tcacaatatc atcaaacatg
    11761 agaagcagtt ttttgaaatt gctccttgtg actcagagtt aaacggcagg ctcacaacct
    11821 ctttcttaaa cggtgttcaa aagcttgcat ctgcggtaat acgcccaatc aaacgaaaaa
    11881 tatgagaagc tatttttgtt tggctgttct tattacttga tgcaggacag ctttttcaca
    11941 acctctgatt cacggtgttc caaaagtagc ttcttcgaaa aataagtcga aatttcacaa
    12001 aaatttgaga agcaattttc gtacattcct tcttatttct tgaagctgac cacttctgtt
    12061 acaacctctt ttttaataac cattctaaaa agataaagtt cgttttttaa gcgtttttat
    12121 aaaataaaaa taaaaatcat tcgattttat ttgaaatatg tatctattat tgatacaatg
    12181 gttcaggatt aaataatata gaacgaggtg ttcacatgtc atctgtagta gtagtaggta
    12241 cgcaatgggg cgatgaaggg aaaggaaaaa tcacagactt tctcagtgaa aatgctgaag
    12301 tgattgcacg gtaccaaggt ggcgacaatg cagggcacac aattaagttt aacggtgtga
    12361 cttataaact gcatttgatt ccttctggga ttttttataa agacaagatc agtgtgatcg
    12421 gaaacggcgt tgtagtcaat cctaaatcat tggttaaaga attagcttat ttacatgaaa
    12481 aaggtgtaga aacaagtaat ttgcgtattt ctgaccgcgc gcacgtaatc ttgccttatc
    12541 atatcaaatt ggaccaatta caagaagatg ctaagggcga aaataagatt ggtacaacga
    12601 ttaaaggaat cggacctgcc tatatggata aagcagctcg tgtaggtatc cgtattgcag
    12661 acttattaga taaagaaatt tttgaagaac gtcttcgttt gaatctagat gacaaaaacc
    12721 gtcaatttgt aaaaatgttt gattcagaac cacttgattt tgacgatatt tttgaagaat
    12781 attatgaata cggacaacaa atcaaacaat acgtcacaga tacttccgtt atcttgaatg
    12841 atgctttgga tgcaggcaaa cgcgtgttgt ttgaaggcgc acaaggtgta atgctggata
    12901 tcgaccaggg aacttatcct tttgttactt cttctaaccc agtagccggt ggggtaacaa
    12961 tcggaagcgg tgtagggcct tcaaaaatca ataaagttgt cggcgtctgc aaagcctata
    13021 cgtcacgtgt cggtgatgga ccatttccaa ctgaattatt tgatgaaaca ggagaacaaa
    13081 tccgcgaagt aggacgagaa tacggtacga caactggtcg tccgcgtcgt gtaggctggt
    13141 ttgattctgt agttatgcgc cattctaaac gagtttcagg tattaccaac ctatctttaa
    13201 actcgatcga tgtattaagt ggattggaaa cagtaaaaat ttgtacggct tatgaattag
    13261 atggcgaact aatctaccac tatccagcaa gcttgaaaga gttgaaccgc tgcaaaccaa
    13321 tctatgaaga attgccaggc tggtcagaag acattacagg atgcaaaaca cttgcagaac
    13381 tgccagaaaa cgcacgtaac tatgtacgtc gtatctcaga gcttgttggt gtacgtatct
    13441 caacattttc tgtcggacct gatagaacac aaacaaacat cttagaaagc gtctgggcgc
    13501 aaatctaagg ataaaaacga cgactgaatc aggacgttct taccagagcg agtcgaagtg
    13561 tttatctata cgataataat aacttgaaga ggtagtgaaa gagacgttta gccttattgc
    13621 cgataggctg tctcttgaac actgtttatt cagaataagg gactgtgaca aaaaccgtgt
    13681 cacagtccct ttttccgaa
//
LOCUS       DACGEU010000071        13659 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.071, whole genome shotgun sequence.
ACCESSION   DACGEU010000071 DACGEU010000000
VERSION     DACGEU010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13659)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13659)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13659
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.071"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(275..967)
                     /locus_tag="IXR40_002043"
     CDS             complement(275..967)
                     /locus_tag="IXR40_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAQ4361878.1"
                     /translation="MQIELQHTHDKETFEKNYKVYVELARDSAMKYGIPLTLDTPYNQ
                     PGIKSHLWVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDDNPTTSEDKPVIDP
                     TRAGAANSTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELAR
                     VRADGIYRPDVNQAYNTLGNVGYHVSFNMRDFPNKKVYVMMRATNDPEGNTKGGAQDF
                     HDKRWYLNIPQR"
     gene            1052..1228
                     /locus_tag="IXR40_002044"
                     /pseudo
     CDS             1052..1228
                     /locus_tag="IXR40_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348541.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
     gene            complement(1404..1973)
                     /locus_tag="IXR40_002045"
     CDS             complement(1404..1973)
                     /locus_tag="IXR40_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAQ4361879.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(2047..2370)
                     /locus_tag="IXR40_002046"
     CDS             complement(2047..2370)
                     /locus_tag="IXR40_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361880.1"
                     /translation="MLLLKTLQERGYLDVHPPEVKIVFFFRYEHQEARRLAGVLNKTL
                     RHRKRISIHVCTRNKPPRYADLVIIDHFFPLDHNEDQKTYLYHPSFGIERLLTDINYW
                     LGKNR"
     gene            complement(2524..3336)
                     /locus_tag="IXR40_002047"
     CDS             complement(2524..3336)
                     /locus_tag="IXR40_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361881.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFCFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLTKVLYQE"
     gene            3690..4538
                     /locus_tag="IXR40_002048"
     CDS             3690..4538
                     /locus_tag="IXR40_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HAQ4361882.1"
                     /translation="MIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGTFSRVQCTPD
                     LLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLEAMAENHATI
                     DNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDDELLLLLDKF
                     EKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAIQLGISPRGS
                     LSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKKQIIHTLVAQ
                     IPIPVR"
     gene            4683..5624
                     /locus_tag="IXR40_002049"
     CDS             4683..5624
                     /locus_tag="IXR40_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HAQ4361883.1"
                     /translation="MELDFIKQLSKETFGYLYIAATRLSQKKYAGYFFHSKKENFFFT
                     SPSFTNRLPSNLCRKKQEILILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFR
                     KSAKREISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNR
                     IDWKLSAHTQEWLYREYDYQEEECSPLFCFWGSPSPKFEPLLDLYFSLWHLRKEKQPE
                     LLILGNRAFHGKDPGHTYFASLEAGDEKAFFAHLKKYAKKQIVLFVPENSPEVSEAIE
                     TLSKDRTVYLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            5614..7785
                     /locus_tag="IXR40_002050"
                     /pseudo
     CDS             5614..7785
                     /locus_tag="IXR40_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
     gene            complement(7897..10068)
                     /gene="copB"
                     /locus_tag="IXR40_002051"
     CDS             complement(7897..10068)
                     /gene="copB"
                     /locus_tag="IXR40_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HAQ4361884.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIR"
     gene            complement(10088..12274)
                     /locus_tag="IXR40_002052"
     CDS             complement(10088..12274)
                     /locus_tag="IXR40_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HAQ4361885.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGLIAVADQIKLEVKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLCLNRHMKK"
     gene            complement(12274..12483)
                     /gene="copZ"
                     /locus_tag="IXR40_002053"
     CDS             complement(12274..12483)
                     /gene="copZ"
                     /locus_tag="IXR40_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HAQ4361886.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            complement(12496..12936)
                     /locus_tag="IXR40_002054"
     CDS             complement(12496..12936)
                     /locus_tag="IXR40_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HAQ4361887.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYYPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            complement(13010..13549)
                     /locus_tag="IXR40_002055"
     CDS             complement(13010..13549)
                     /locus_tag="IXR40_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAQ4361888.1"
                     /translation="MKIIVIGQSGSGKSTLARKIKEITDFPLLPLDLLWHTTDYSIQA
                     KKWFLQEQQLFMVSNPSWIVEGNYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLK
                     RKINKKSRPDMPESFSEKLNREYLEFLSFIWHFEENNEPKIQQLIQVANARNKLIILK
                     TRREKQEFLTKLKIESKNN"
BASE COUNT         3846 a         2847 c         2420 g         4546 t
ORIGIN      
        1 acatttgtat tttatcaaag ttttattata cttgtcaatt tgtgtacatc ctaaaatata
       61 agctatttgt ttacttctgt agaatatata ctttgttgtt agataagttg cacatgttta
      121 tagaatctaa ataataaatt tttatgtacc gcccctcaaa gtgaactgaa ccccaaaagt
      181 tgaactattt aatggactgt ttccgatatt ctactggaga tagtccatta aatagttcaa
      241 cttttggggt tcagttcaaa gaggggggga ttttttatcg ttgtggaata tttaaatacc
      301 aacgcttgtc atgaaaatct tgtgctccac ccttagtatt tccttctgga tcgtttgtcg
      361 cacgcatcat gacgtatact ttcttattag ggaaatcacg catattgaaa gatacatgat
      421 agccaacatt tcctaaagta ttataagctt gatttacgtc tggtctataa atcccatcag
      481 ctcttactct agctagttct tttccagtat tgtagtccat aatgaaaata tactcgtatt
      541 tataattagc aatgtgccat ccagctacat gcaagtttgc gttttcgatt tctccgaact
      601 gatcaatgtg ggcgtaattt gttccatctg tcagcgtaga atttgcagca cctgctcgag
      661 ttggatcaat tactggttta tcctccgaag tagttggatt atcatccgta aaaccatgag
      721 ccaaatcata ggctagtttt tctttactta cacccatttc agaaagataa ccgtaaggat
      781 ctgtatgatc gccccaaata ttttgtgtta cccataaatg cgatttgatt cctggttggt
      841 tataaggagt gtctaatgtt aatggaatac catatttcat tgctgaatct cttgccaatt
      901 caacgtatac tttatagttc ttttcaaaag tttctttatc atgtgtatgt tgtaactcga
      961 tttgcacagg acttttggct cacgaggttg tcctactcta catcttgctg atagatatgc
     1021 tgaaaggaaa acaccaacat tatgttttgc tttttcagct agaacgagac aagcaggaat
     1081 acctttagaa gatatcaaag gttttttagg tcataaagat gtttccacta cacaagtcta
     1141 tgcccatatt tctcccgaag tgaaaaaaag atcaatgaat caactagaaa actatataga
     1201 agagcaaata aaaaagcact caaattgagt gcttttttaa gctcactatc actaaaacta
     1261 tcactaattt tatttataag cgaacatgtt tctatcactg attttttaaa tctagcgaaa
     1321 aacccttatc ttaaaggcgt tcgttcaatt ctttggcaag gtcttcaaag cctggcttgc
     1381 ctagaagtgc gaacatggtt ttcttatagc tcatgtagaa aaattttctt gatgatgatt
     1441 ttatccatca attgagattg actgttttgc tctcctatga tttcagctat gattgtccga
     1501 ttttgcggtt ttcttcttaa ctggtagttg attttcccag tttccatcaa ctcgctaagc
     1561 atatccacga ctccgccaaa tccggtcttt ttcgtaataa aacctagtgc taccattcgt
     1621 tcatctagat tttttgctgt aatcgtcaca ccagtaatga gcgagtgctg taatgtttgg
     1681 gccagctctt ccatcccttc agcattggat acgacggaag ctgttttgtt aataggttct
     1741 tcgtttattt cttttggttc tttcctctcc actttcactg tttgacgaag gacatctagt
     1801 tcttgcaaga gcgtttcgta ttgttcttgg gtcagcatca cgccagctac tttttcacga
     1861 ttaaatatat atacgccagt tcccgcgtct cgcgcttgag caaatacatc catcggcgat
     1921 cgtttcactt ctgtgatcga agatgtggga acttctaatt tctttaattc caatggattt
     1981 cctcctttac taatcgcttt ttattatagc acagactgac ttgttttgat cttttttcca
     2041 aaggttttat cggtttttgc ctaaccagta attgatatcg gtaagaagtc tttcgatacc
     2101 aaatgaagga tggtacagat acgttttttg atcttcgtta tggtctagtg gaaaaaaatg
     2161 atcgatgatc actagatctg cataccgagg cggcttattt cgagtacata catgtataga
     2221 gatccgtttt cgatgtctta gcgttttgtt cagtacccca gcaagtcttc ttgcttcttg
     2281 gtgttcatag cgaaaaaaaa agacgatttt cacttcagga gggtggacat ctaaataccc
     2341 tcgttcctgg agtgttttca gtaaaagcat cccccactct actgcggggt gtgcaagtgc
     2401 ttgttggatc gctagccgaa attgatatag tttatctttg gaattgggaa atttttctaa
     2461 tgtttcctga taataacgaa cttcttctat cagccggtca tggataccaa ttacgtaacg
     2521 aagtcattct tggtaaagta cttttgtcag ctttgatttg ctttcgctct caaattcgct
     2581 attcagccaa aacagcgaat caagcttttc agtcacaatc gtcaatttcc gatagtcttg
     2641 tgtctcttct atccgtttcc accgcttttc agtaatctgg ttacagctca agcgcaaaat
     2701 tgctagataa tttttttctt ttattggcaa aatctgctcc tctctaaata gcaattcagg
     2761 aaacaattca aagaatagtg ttcgactgtc tcctaaaatc tcgatttctg ccggatcctt
     2821 tctttgcttc aataattgga tgaacatctc agaaaaggac tgctctccat catctgcaaa
     2881 aaaatgcgga aaatctttca aaaagcaaaa cagcagatat cttacttttc tttctgaacc
     2941 aaagatctgt gcttttttat aagaaaaaga aaggtggtac tcgccaaacc actttctcaa
     3001 tcgctcttgc gtagaacgat cgtacttctg ctcgtaaggt tcattcaata gcagattttt
     3061 cagtaaacaa aacgggggtg attggatcag aaaaacaaac aagagataag gttcgctata
     3121 tccttgatca taaactaact gaacggtttt cttatgaaga atcagctgaa tgggacagtc
     3181 gctttccgcc aaacgtttca gatgccgatc cactgtttta acatcgattt tcagttcttc
     3241 agctaaatca gcttttcgcc agatcaaatc tttcattaga ttgattagtg aaaataaatt
     3301 ctgtgcattt tttgataata gtttttgcca tctcatcgat catttctcac ctgatttcta
     3361 aacatattgt ttgatcaaaa tgggttcact cctaaaaaga taaaaaactc cctttctatt
     3421 tatttaaata cgcaaatctt cctcattatt ttttatttta ctcaatttaa tcgtattctc
     3481 atttcaaaac gaatgtactt taaaaaaaca taataagatc actttgcttg taggatgtat
     3541 tcccttccat tacaatgaaa taaatagcga ttttatgaga aggtgatgtg aaaatggaag
     3601 aaaaaataga agaatccaaa caaaaaatcg atcagttgat ataagaatta gaaaaagcgg
     3661 tcatcggcaa acgttcaact atccaattga tgatcgtggc cctattagca ggtggtcatg
     3721 tcttattcga agatattccc ggtgtaggta aaacgttact ggtcaaagca ctagcaaaag
     3781 ctgtacaggg aaccttcagc agagtccaat gtactcctga tctgctgcct agtgatattc
     3841 ttggtttttc cgtatacaat tcacaatcaa aagagtttga atttcgtccg ggaccgatct
     3901 ttaccacgat cttgttagca gatgagatca atcgtacgac tcctcgtact cagtcagcac
     3961 ttttagaagc aatggccgag aatcatgcaa cgatcgacaa caatacatac cctctagaca
     4021 atcatttttt tgtcttagct acgcaaaatc caatcgagta cgaaggaaca tatcctttgc
     4081 cggaagcaca gctcgatcgt tttttattcc gactacaaat cggttatcct tcttttgatg
     4141 acgaactttt gctacttttg gataaattcg aaaaagtgtt ggataactta aatgaagtat
     4201 tgaacagtta tgaaatagaa gaaataaaaa caaatgtggc gaatgtcttt gtcagtcccg
     4261 aagtggcatc ttatgccttg cagttagtgt cagcaacaag aagtcatgct gccatccagc
     4321 ttggcatcag tccacgagga agcctttcct ttattcaggc agcaaaagct tatgctttaa
     4381 tccatgggag aaattacgtc acgcccaaag atttgcagga tttagttcct tacgtgtttt
     4441 cccatcgcct gattttttac gatcgttcat tgaaggaaga cgaaaagaaa caaatcattc
     4501 atactcttgt tgcacaaatt cctattcctg tgaggtagat tgaggtagac aatggaaaaa
     4561 atcaaagatt atttcattaa ttttgtgtta tttctggtat atttcatcat tgtgcttttt
     4621 gctcttgtat tcaacaattc tttaggctgg ttcttgttgg ccttttttac tctttatgta
     4681 tcatggagct tgatttcatt aagcagcttt ctaaagaaac tttcggttac ttgtacattg
     4741 cagccactcg tttatcgcaa aaaaagtatg caggttattt tttccatagc aaaaaagaga
     4801 actttttctt tacctctccc tcgtttacaa atcggcttcc cagcaatctt tgcagaaaaa
     4861 aacaagagat tttgattctt acaaataaac cgcaagaagt ccaattgctt tggcagccaa
     4921 aagaaagagg atgccatgaa acattaactg tcatttttac agcctatgat agtctaggac
     4981 ttttcagaaa aagtgcaaaa agagagatct cttttcctgt gactgttctg cctgcttttt
     5041 gtaagattca agcagaaaaa ttacagagag ttctggaaaa aaaacagcag ctgaacgcgt
     5101 accaaagagg tcttgatttt cgggaacatc gcgcttatcg tccaggtgat tctttcaacc
     5161 gaatcgattg gaaattgtct gctcatactc aagagtggtt ataccgtgaa tacgattatc
     5221 aagaagaaga atgttctcct cttttttgct tttggggttc gcccagtcca aaatttgaac
     5281 ctctgctaga cttgtatttt tctttatggc atttgagaaa agaaaagcag ccggaacttc
     5341 tgatattagg caaccgcgcc tttcatggca aagaccccgg tcatacctat tttgcttctt
     5401 tggaagctgg cgatgagaaa gcttttttcg cacacttgaa aaaatatgca aaaaaacaaa
     5461 tcgtcctctt tgttcctgag aattctcctg aagtctcaga agctattgaa acattgtcaa
     5521 aagatcgaac ggtttatctt gtttatttcg tagaaaaaca actcatggtc caagaaaaag
     5581 acaagatatg ttcattgcca ggaggtgaat ggattgacga ttaaacggga aaaatggctg
     5641 cgtggcgttt actcctttgt gatactaagt gtaggtgctc cgatatttgt agtagctaat
     5701 caattgcaaa acagctacct tcttatccta actattggtg tcctatgcct tattgtctgc
     5761 tgtattccta aaaaatgggt acgtttgctg ctttctttgc cagtaatgat aggttgtttg
     5821 tttttatatt ttccttcgaa gacattttcc atattatgga tcttacagtt tttttcgtca
     5881 gtcacagagg aattcttcca tctatcccaa ggtaaacttt attatttgcc agaaaagaca
     5941 gctttttttc tcataatgtt gctgatctat ttatttatta cattgaccgt ggattacgac
     6001 tattggtacg caccctttct ttctttgatg gcttacttca tgatgcttac cgtttttcgg
     6061 aaaaaagatt tactgtacga aatgattgcg gtagtaactg ttttgttcgt gtatctggca
     6121 gcaaggcaat ttttctccat ccggttgttg tcgggaaaca ctcgattcca gtcattgact
     6181 acagttctgc ttatttgttt cttaactttt agcgctatct tgcctttata tcttccgaaa
     6241 gtacaccaat ctctcgagga aacgagtgaa ccgatccgag aatatcttaa tgatgaaggg
     6301 ctttatgaca cactccatga gtatcaatta accggaagtg caagaacagg cttcagtgag
     6361 aatgatgaac agcttggtgg acctttatat gataatggcg aagttgtttt tacagcgaac
     6421 caaaaaggaa atggctattg gaagatcgaa aataaaaatc attacaccgg ttctggatgg
     6481 atagaagatc aggacgcacc catccaacca atccaagaat tccctgttga catcacgagc
     6541 taccaaaccg ttatagaaga caaagaaaac attacattga ccctaaaaaa acaagttttc
     6601 ttaccttatc cttatggaaa tactaccttg actgattttt cattagctag tggacaaacg
     6661 ctttactatt tgcctgaaag ccagcgattc attcctgtcc cgaatgaatc gacacgttct
     6721 gcaactttac aaacagaaag gttagttttt acgagagaag aattaaaaag cagtcagtta
     6781 aaagctgatg atttagaaaa tcagcagaca aatcttcaat tgccaaaaag tttgcctaaa
     6841 cgtattgagg acttggcggt cgaattgacc aaaaatgaag caactttaat tcgtaaagtc
     6901 gaagctgtct aacagtattt aaaaacaagc ggaaatttcc gctattccaa aacggatacc
     6961 gggcatactc caaaagaaca cgattatgtg gattatttcc tctttgattc aaaagtcggc
     7021 tattgtgaca acttttcaac ttctatggtc gtccttcttc gaacacttgg tatcccagct
     7081 cgctggacaa aaggttttac aaatgggctc agaacaggca cagataatca agggaatgag
     7141 gaatacagca ttctcaatag tcatgctcat tcttggccag aggtatactt tcctggattt
     7201 ggctggcttc catttgaacc aaccccttca tttgccaatc caatgggttc acaaccagtt
     7261 gctgaaacaa ccgaaaccgt ccagcctgct atcgaacaac caaatgaaag cgaaaatatg
     7321 gcagaaacta tttccagtga gagatctgag gtcattccat cagaagaaac aacactcaca
     7381 ccagcttata aaatcgtctt attcagcctt ggagtgtgtt tatccgtctt gttgttcttt
     7441 ctattgttat tcagaaaatc tctgcgctgg acaagttatc ttatctatct tcattttttt
     7501 gcttctacta atacgattgc atatcaaaaa cttcttaacc ctttggaaac attggtaccg
     7561 cgcaaacccg cagaatcttt gcaggaatat agcctgcgaa tagaacaaga attcaagcta
     7621 gatctgcgtt tcattcgatt aactactcaa tatgaagcag aaatatatgg acgacaagca
     7681 gatccggtaa aattcgataa aaaaacctat ttagaaataa cgcatataat aagaaaaatg
     7741 gtatacaaaa aaattctgac aaaagggagc cgcttcaaaa aataagataa aatttctgga
     7801 gaatctactt ctggaatgcc gagaaccagc tgattgagta tcgattactc gaaaaaaagg
     7861 ttgtgacacg ttttttgtca caaccttttt tcattattat ctgattttca atgtcaaagc
     7921 atttagagct acaactaccg tacttaacga catcaagaca gcaccaactg ctggacttaa
     7981 tatgatacca attggcgcaa gaattccggc tgctagcgga attgcaagaa tattgtaacc
     8041 tgccccccac cagaggttct ggatcatttt ctttcgcgtt tgcttggcta gatcaagaaa
     8101 atgcaaaata tcttttggat cgctgtttgt caatacgaca tccgcagaat cgattgcgat
     8161 atctgtccct gcaccgattg ccatcccgat tgaagcacgg gctaaacttg gcgcatcatt
     8221 gatcccatca cccaccatga ttactttttt cccttggtca aggtatttct ggacaacagc
     8281 ttctttatca tctggtaata aaccgccata atattcttcg atccctaaat aatctgctac
     8341 tgcttgggca gcgtttttat tgtcaccagt aagcatgaca ggagtgattt ttctttcttt
     8401 caatgttcgg ataaattctt ttgcttctgt ttttactacg tcacctaaag caacgattgc
     8461 agctagatga ttttctaaaa tcaggaagct gatggtattt ccttgttctt ggtaaggttt
     8521 caataatgct tgttctacgt ttaatccgag acgctcaact tctttttcat taactatttt
     8581 cacttgttgt tttttgactg ttgcctctag cccgactcct gaaagatttt ttagattttc
     8641 agcttgataa ggcttgattt catgttcttt caaataattc ataatgccaa cagccaatgg
     8701 atgattggca ttcgcttcca aggctcctag atattgaagg atttcatttt tattgaacgc
     8761 atcatcaagt acttcgacac ccgttacagt aaattttcct tctgttagtg ttcctgtttt
     8821 gtccagcatg atcacatcta gatcattggc ttgctccagt gcattgcggt ttttcaaaag
     8881 taatccgttt ttagctgcta ttgatgtgga acgagcaaca actaatggga tagctaaacc
     8941 tagagcatga ggacaggcga tgataaagac tgttaccata cgttctaatg cattaggaag
     9001 atctgtcaag aacaaccagg cgatgaatgc caggataccc acaattaatg cgacataaaa
     9061 cagccatttt gccactttgt cagataatga ctctagcttg gatttttctc cttgtgcttt
     9121 tcgcaccatt tccataacct tcgctagata accattttca ccagttccag ttacttcgat
     9181 ttcgatcgtt ccatccccat tgatagaacc gccaatcact ttgtcattgg cttgtttttt
     9241 gattcctctt gattcgccag tcacagctga ttcgtcaaca attgtttcac ctttcaagat
     9301 tacaccatct gttggcattt tatcaccaga ccggacgatc aaacgatcac cttcgtttac
     9361 ttctttcaat gaaactgtct cttcttttcc atctttcgtc aagcgtttca ctgattctgg
     9421 cagtaattct gctagttttt gtaaagcatt gctggcattc gacacagcat tcatttcaat
     9481 ccagtgacct agtagcataa taacgatcaa agtagccaat tcccagaaga aatccatgac
     9541 gtgtgtatgt ggattgagca gatttgcgat aaacgaatag acactataaa tatatgcaac
     9601 tgtaatcccc atcgcgatca gtgtcatcat agcaggactt ttttgtttca attccatctt
     9661 agctccactt aaaaatggct gaccgccata gataaatagt atagttgcta agatcaatac
     9721 gagccaatca gaaccaggaa acgttacttg aaatggaaat tccattccca tcattggtga
     9781 aaaaagaatg attgggatag ctaggataag cgatagccaa aatttttgtt tgaaattccc
     9841 catgtgcatg gaatgatcca tgccgccgtg ttcgtgatcc atgtgcatcg aatggtccat
     9901 ttgtttgctg tttgctatat ctccatggtt atgtcccatg tgcatggaat gatccatctg
     9961 actatggtca tgtttcatct ccatctgttt ttcatgagat tctgtacttt ctttgtttac
    10021 tacttctttt ttatgctcat gttttttctc catatcgttc ccattcattt ttactccatc
    10081 ccttctctta ctttttcatg tgtcgattta agcacaggga gttcaacaat acactgacgg
    10141 aactaaacgc catcgctcct cctgcaatga ttggattcaa aaagcctagt gcggcaaaag
    10201 gaataccaat cgtattatag acaaaagccc agaaaagatt ttgtttgatt tttctcaatg
    10261 tcaacctaga caactcgatt gtttgtgcaa tggatgccaa actgctattc atcagcgtca
    10321 catcggctgt ttccatcgca atgtccgttc cacttcccat tgccataccg acatcagcta
    10381 atgctaaggc cggtgcatca ttgattccat cgcctgccat accgactttt ttgccatctt
    10441 tctgaagttt ttctacgtag gctgctttat cctctggaag tacttcagca aagatatgct
    10501 ttggatcaat accaacttgt ttaccaatcg tttcggctgc cagtttgttg tctcctgtca
    10561 gcataaaaac atctaatcct ttattctgga gctgcttgat tgcttgtttg acttctagtt
    10621 tgatttgatc agccacggca atcaacccga tcacttgctt ttcatcagct aaaaacatga
    10681 ctgtttttcc ctgctgttct aattctaacg cgtgttcttg gtattcatca aatgataggt
    10741 tcaattcaat taatcgttta cgtgtacccg caaaatagcg tactccgtta atcgtaccgc
    10801 tgattccagc acctgggtgg gctgtaaaat caatcatatc gtatgttgct gcttcttgca
    10861 gttttccgta ttccacgatt gctttaccta gtggatgttc agaagcttgt tctaaagtat
    10921 aaaaaataga taggacttct ttagaaccga ctagatctgt aactttgggc tttccttctg
    10981 taatcgttcc agttttatcc aaaacaatgc tgtctaagtg agcagctgct tctaatgctt
    11041 ctccgccttt aattaaaatt ccatttcgtg caccaacacc cgttcctacc ataatagctg
    11101 ttggagtcgc taaacctaat gcacatggac acgcaatgac taatacagag acactatgga
    11161 tcaatgcgag ttgccaatca ccagtgatca aacctgtagc tatgagcgtg ataaacgcga
    11221 tgactaatac gatcggaaca aaaatccctg agatccgatc tgcgattttt tggattgggg
    11281 ctttgctccc ttgagcatct tccaccattt gaatgatttg cgctaatact gtctgcttgc
    11341 cgacttgtgt aacttccatg tgaagtagac cattcgtatt gattgtcccg ccaaagagcg
    11401 tgtcatccgg attcttttct acaggaagat tttcaccagt aagcatactt tcatctatcg
    11461 cactgcttcc tgaaataatt cgaccatctg ctggaatctg ctcaccagga cggatgacta
    11521 gttgatcacc aacgactact tcttcaatcg ctaacgtttc ttctttcccg tttcttatca
    11581 cttgggcggt ttttgtttga agagacatca attgtttgat tgcattacct gttttcgttt
    11641 ttgctgtatg ttccaaatat ttgccgagca aaatcagcgt gatgatcata ctgctgcttt
    11701 caaaataaag atcttggggg tgtccacgga aaaatccgtt gtaaatgctc aatgcaaagg
    11761 cagccgatgt tccaattgct accaatacat ccatatttgg tgctttcgtc ttgattgcat
    11821 ggtacgcacc tttataaaaa cgagcaccga cataaaattg gacaggagca gacagcacta
    11881 actggacgat tggaaaatga aaaaagtgaa caatcgccgc atggcttcct aacatcatag
    11941 caatcattga caacatcaac ggcaaagtca aaaccgtact caatataaga tcgaatagca
    12001 tttttttcaa atacgcttgc ttttcttctg caattttttg tttgtgggct tcatcgtaca
    12061 aaattgcacc atagccgatg ttttctacgc tttggattaa tttttcagtg gtcgtccctt
    12121 catatttgac acttgctttt tcagtggcca agttgactgt ggcattgacc acaccaggtt
    12181 gtccgttcag ctctttttcg atcctagcag aacaatttgc acaagtcata cctgtaatga
    12241 cgaacgtatc cattttggtt tctgctgttg ccatcaaatc acctctgctt tataacccaa
    12301 tccattgatt gcttgacaaa tcttttcgga ttgaactttt gtttcatcaa acttgaccgt
    12361 accgtttgct tttttcaaat ttactttcac tttttgcacg ccgtcaagtg cgcttactgt
    12421 ttcttctact cttgctgcac aatgattgca gctcatacct tcgattgaaa attgttgttt
    12481 cattttttct tcctcctatt gatgttgttt acattcacat tgacctggga tacagttaca
    12541 ttcgatcgta tctactggtt gcttttgttc cagttgtttc aaaatctcat tgatatcttc
    12601 ttgagtcaaa gtggcttctt ctactagatc cgcaatcgtc tctccaatcc tttttgcaca
    12661 gatatgggaa aaaagatttt ccgtcgcact gcgaactgtt tccatctccg agacagctgg
    12721 ataataaatg aatttttttc cttcttgttc tgtccagatc acttcttttt ttaccaaacg
    12781 acccagcaaa gttttgatcg ttgctggttt ccaatccatc gaatcagcta agatctgcgt
    12841 gatttcttgg gctgtcgtct gtccaagtgt ccaaataaca cgcatgatct cccactctga
    12901 atcactgatc tttactggcg ttttgacttt ttccatttat ttcacacctt tcgtttacaa
    12961 atgtaatcat tatcttatga atacagatta cacttgtaaa caaaaactgt caattatttt
    13021 tgctctctat tttcaattta gttaaaaatt cttgtttctc tcgtcttgtt ttaaggatga
    13081 tcagtttatt tcttgcatta gctacttgga tcagctgctg tattttcggt tcattgtttt
    13141 cttcaaaatg ccagataaaa gataaaaatt ctaagtattc cctgtttagt ttctccgaaa
    13201 atgattcagg catatctggc cgagattttt tgtttatctt tctttttaga gaacgccaaa
    13261 ctactcggta gatggcgaga taacgcggca ctttaagcca aatgatctta tctgcttctt
    13321 taatcctttc ctctaatgta gaagtataat ttccttcaac gatccatgac ggattagata
    13381 ccataaacaa ttgctgttct tgcaaaaacc acttttttgc ctgaatactg tagtctgttg
    13441 tatgccataa aaggtctagc ggcagtagcg gaaagtcggt gatttctttg atcttccttg
    13501 cgagggtcga ttttcccgac ccactttgtc caatcacgat gatcttcatt cttctccctc
    13561 acttctcttt ggaatttggt tcgatcatac cacttataac gccgcaaaaa aacaagggac
    13621 tgtgacaaaa gtcgtgtcaa agtcccttgt ttcgaataa
//
LOCUS       DACGEU010000072        13568 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.072, whole genome shotgun sequence.
ACCESSION   DACGEU010000072 DACGEU010000000
VERSION     DACGEU010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13568)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13568)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13568
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.072"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            475..717
                     /locus_tag="IXR40_002056"
     CDS             475..717
                     /locus_tag="IXR40_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3781 domain-containing protein"
                     /protein_id="HAQ4361889.1"
                     /translation="MENELLENLGRLHTTELGVIRIKKNLSLNVENVIEWCKEKISLS
                     NAEITRKGKNWYITIDNCIITVNAYSYTVITAHKVK"
     gene            714..1184
                     /locus_tag="IXR40_002057"
     CDS             714..1184
                     /locus_tag="IXR40_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002606082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAQ4361890.1"
                     /translation="MINFSIKELNAFAVIGQEVELTNYQKKNIQISTQFWRKFNSSLK
                     KAYLSQSGNWVKYAFMERRNGKLYYFCSIPQRTITPEGFLYKEIPSYKYLVVEHIGAM
                     DKIYETYGKIYEEIIPSTSYIPIKDIILHFEKYDYRFHWNSDNSVIEIWIPIQD"
     gene            1312..2526
                     /locus_tag="IXR40_002058"
     CDS             1312..2526
                     /locus_tag="IXR40_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAQ4361891.1"
                     /translation="MNDKNFIEELRQKREEYGVTQTRLAVACGISREYYNRIEKGKQP
                     LNDELREIIEKQIERFNPQEPLFLLIDYFRVRFPTTDALAIIRDVLQLKSNYMLYEDY
                     GKYGYESKYVLGDINIMCSMQEHLGVLLELKGKGCRQMECYLLAQERSWYDFMLDCMT
                     AGGVMKRLDLAINDKAGILDIPKLKEKYKAGECMSYFRMQKDYSGTEKCGSDLPKNTG
                     ETLYLGSTSSELYMCAYQKNYEQYVKNGTEIEDTEIKNRFEIRMKNERAYYAVVDLLT
                     YRDAERTAFSIINHYVRFVDREDDKPKSQWITNDDWAWFVGENREPIRLTTKPEPYTL
                     QKALHWLQRQVAPTIKMVQALDRENRTTILKDMIEQAELKDKHKHLLQLEKSTIEERI
                     DTAVPQENDGIF"
     gene            complement(3236..3424)
                     /locus_tag="IXR40_002059"
     CDS             complement(3236..3424)
                     /locus_tag="IXR40_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008787514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361892.1"
                     /translation="MAVREYHYLTVQVMAIKEDKSFTRTQIGFRSLLQGKGRGVFVST
                     ASCLSNVLNSFIQLSKND"
     gene            3515..3724
                     /locus_tag="IXR40_002060"
     CDS             3515..3724
                     /locus_tag="IXR40_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008394616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA wybutosine-synthesizing protein 3-like
                     protein"
                     /protein_id="HAQ4361893.1"
                     /translation="MNCLERFYRKGVCVIDNAVKTIQKKNGKCGIGNRGKTKIVVKEH
                     FSEKGKTMEELLTDVMLEKAKQTIA"
     gene            3836..5449
                     /locus_tag="IXR40_002061"
     CDS             3836..5449
                     /locus_tag="IXR40_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003019515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4368 domain-containing protein"
                     /protein_id="HAQ4361894.1"
                     /translation="MKQQIYNTALYLRLSRDDELQGESSSITTQRSMLRLYAKEHHLN
                     VIDEYIDDGWSGTNFDRPSFQRMIEDIEAGKINCVVTKDLSRLGRNYIMTGQYTELYF
                     PSHNVRYIAIDDGVDSEKGESEIAPFKNIINEWVARDTSRKVKSAFKTKFAEGAHYGA
                     YAPLGYKKHPDIKGKLLVDDETKWIIEKIFSLAYQGYGSAKITKQLRAEKVPTASWLN
                     FTRYGTFAHIFEGKPESKRYEWTIAHVKAILKSEVYIGNSVHNMQSTVSFKSKKKVRK
                     PESEWFRVENTHEPIIDKEVFYRVQEQIKSRRRQTKEKATPIFAGLVKCADCGWSMRF
                     GTNKTNKTPYSYYACSYYGQFGKGNCSMHYIRYDVLYQAVLERLQYWAKAVQQDEEKV
                     LNKIQKAGNAERIREKKKKASTLKKAENRQNEIDRLFAKMYEDRACEKITERNFVMLS
                     SKYQKEQIELEQQITSLREELSKMEQDMIGAEKWIELIKEYSVPKELTAPLLNAMIEK
                     ILIHEATTNEDNERIQEIEIYYRFIGRVE"
     gene            5484..6695
                     /locus_tag="IXR40_002062"
                     /pseudo
     CDS             5484..6695
                     /locus_tag="IXR40_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
     gene            6718..7644
                     /gene="glsA"
                     /locus_tag="IXR40_002063"
     CDS             6718..7644
                     /gene="glsA"
                     /locus_tag="IXR40_002063"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HAQ4361895.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            7852..9312
                     /locus_tag="IXR40_002064"
     CDS             7852..9312
                     /locus_tag="IXR40_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361896.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIREIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            9533..11296
                     /locus_tag="IXR40_002065"
     CDS             9533..11296
                     /locus_tag="IXR40_002065"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HAQ4361897.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            11380..11838
                     /locus_tag="IXR40_002066"
     CDS             11380..11838
                     /locus_tag="IXR40_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HAQ4361898.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            11947..12630
                     /locus_tag="IXR40_002067"
     CDS             11947..12630
                     /locus_tag="IXR40_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HAQ4361899.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            12777..13391
                     /locus_tag="IXR40_002068"
     CDS             12777..13391
                     /locus_tag="IXR40_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HAQ4361900.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
BASE COUNT         4711 a         2153 c         2844 g         3860 t
ORIGIN      
        1 ttttccgcca tgcttgcaag ggggcggttc gcttcggcgg ttcggcgagc ttgcgagccg
       61 ttcaaagccc ccgttatcta acaagggggg cacaaaaaac aagaaacact atacactaac
      121 aagcggaaaa cgctgtattt ataaggcaaa accccatttt tacagtagtg atataaattg
      181 tacctatatc actatgaaaa ttgaatagta aatatgagaa agacagttga tttcaaaaaa
      241 taagaaattg attgtcgttt tcttttgcag aaatttaagt gcaggcaatt atggtagttg
      301 tcgtaattgc tgtcagctca gtgtttatca ctgatggtgt gaaagattta cggttggaga
      361 tgttcaataa gattattggt gcttaattat ttttattgta gtgctgatat gagaatgtta
      421 taattggggt ataaaacata caaataaatt tgctgaaaaa tgaggtatca aaatatggaa
      481 aatgaattac tggaaaactt aggaagactt cacacaactg aacttggcgt tattagaatt
      541 aaaaagaact tatctttgaa tgtagaaaat gtaattgaat ggtgcaaaga aaaaattagc
      601 ctttctaatg cggaaatcac aagaaaagga aaaaactggt atataacgat tgataattgt
      661 attataacgg taaatgcgta cagttatacc gttatcactg ctcacaaggt aaaatgataa
      721 atttttctat aaaggaatta aacgcatttg cagttattgg gcaggaagta gaactgacta
      781 attatcaaaa aaagaatatt cagattagta cacagttttg gagaaagttt aacagtagtt
      841 tgaaaaaagc gtatctttca caatcaggaa attgggtaaa atatgctttt atggaaagaa
      901 gaaatggaaa actttattat ttctgttcta ttccccaaag aaccattacc ccagagggct
      961 ttctgtataa agaaataccg tcttataaat atttggttgt ggagcatatt ggtgctatgg
     1021 ataaaatata tgaaacttat ggcaagattt atgaagaaat tattcctagt acatcgtata
     1081 ttcctataaa agatattatc ctacactttg aaaaatacga ttatcgtttt cattggaata
     1141 gtgataattc agttattgaa atttggatac ctattcaaga ttagaagcaa ttttatatcc
     1201 atacacacaa agcagttagt cttaggattg actgcttttt ctatacagat ttttaatgac
     1261 aggcaattat caattatggt agttgccttt tttgattgga ggaattgaag aatgaatgat
     1321 aaaaacttta ttgaagaact aagacaaaag cgtgaggaat acggagtaac acaaacaagg
     1381 cttgctgttg cctgtggtat cagccgtgaa tattacaacc gcattgaaaa aggaaaacag
     1441 ccattgaatg acgaattaag agaaatcata gaaaaacaga ttgagcgttt caatccgcaa
     1501 gaaccactat tcttattgat tgattacttt cgtgtccgct ttcctactac ggacgcattg
     1561 gcgattatcc gtgatgtatt acaactgaaa tctaattaca tgctttatga agattatgga
     1621 aaatacggat atgaaagcaa atatgtactt ggcgacatca atatcatgtg ttccatgcag
     1681 gagcatttag gtgttttatt ggaactgaaa ggcaaaggct gtcggcaaat ggaatgttat
     1741 ctgctggcac aggaacgctc atggtatgac ttcatgctgg attgtatgac ggctggtggt
     1801 gtgatgaaac ggcttgattt ggctatcaat gataaagcag gaatattgga tattccaaag
     1861 ttaaaggaaa aatacaaggc tggcgaatgt atgtcctact tccgtatgca gaaagattac
     1921 agcggtacag aaaaatgcgg tagcgattta ccaaagaata caggagaaac cttatatctc
     1981 ggttcaacaa gtagcgaatt atatatgtgt gcttatcaga aaaattatga gcagtatgtc
     2041 aagaatggca cagaaattga agatacggag attaagaacc gttttgaaat acgcatgaag
     2101 aacgaacgag cctattatgc ggttgtagat ttactgacct atcgggacgc tgaacgcacc
     2161 gctttttcta tcatcaatca ttatgtccgc tttgttgaca gagaggacga caagccaaaa
     2221 agtcaatgga taacaaatga tgattgggca tggtttgtag gggaaaacag agagccgata
     2281 cgcttaacca caaagccaga gccttacact ttacaaaaag cgttgcattg gctacaaaga
     2341 caagtcgcac caaccataaa aatggtacag gcattagaca gagaaaatcg tacaacgata
     2401 ctgaaagata tgattgagca ggcagaacta aaagacaagc ataaacattt attacaatta
     2461 gagaaatcaa ccatagaaga acgtatagat accgctgttc cacaagagaa tgacggtatt
     2521 ttttaatgta attgaaaaat ttcagattta gtcagcaaag agctgttttc attccctatg
     2581 tgaagtgaaa gaagaaaaat aaatttttta ttaaatctgc aacaaaatgg ctacttgcgt
     2641 acagatatgg tgcgagaaaa ggaaatctaa actttttttg aaaataggtc attaaatcgg
     2701 ggcttgctgt ccctatatga agtgaaagaa gaaaaaagtt ttgaaaaaat gacggaaatt
     2761 cgtgattagt ggacagtctt ctgtgaaaag aggaaaaaca tcatcatttt gtattcaaac
     2821 aggcattagc agttgagtgt tgatgtgaaa agatgaaaat actttgttct caacttaaca
     2881 atttaaggtt tccgttccct atatggtgca aagaaaatat ttcattctat tgttggcagt
     2941 aacggtatgg tttgggtagt tagggtgtga aaaggaaaat attctttttt catcatcaac
     3001 ttagcaaaat gacattttct atccctatat ggtgcatgaa aagaagttaa aatttttcca
     3061 tttaaactta gcaaatggac gtttgctgta cagatagtag tgaaaaagga gaaaatcaac
     3121 cgttgattgc caaaatgaac cgttccattt gtactaataa tggaaaaagt tttggatttt
     3181 ggttacgttt ctcctctttt ccaacgcgat atataggaaa gacgattttt ttctttcaat
     3241 cgttctttga caactgaata aagctattca atacgtttga cagacagcta gccgttgaaa
     3301 caaatacgcc acgacctttc ccctgcaaga gcgagcgaaa acctatttgt gttcttgtaa
     3361 aagatttgtc ctcttttatc gccatgacct gtactgtcag ataatgatac tcccgtacag
     3421 ccacagcttg agcattaaga gcgtcgcacg caatgggtac ggctacataa gaactatgca
     3481 gaggtggaac tcctgtgggc tatgacaaaa gccgttgaat tgcttagaaa gattttacag
     3541 aaagggggta tgtgttattg ataatgctgt aaaaacaatt caaaagaaaa atggcaagtg
     3601 tggcattggc aacagaggaa agacaaagat tgtagtaaaa gagcattttt ccgaaaaggg
     3661 caaaacaatg gaagaacttc taactgatgt catgctggaa aaagcaaagc agacaatcgc
     3721 ataaaatcgg tgcagttgta agaaatagat tgaatgacaa aaagtacccg tgttatactt
     3781 tacttgcaag caggtattgt aaacacgggt tagttataaa ggaggataac tgacaatgaa
     3841 acaacagatt tacaatactg cactttatct taggttaagc cgagatgatg aattacaggg
     3901 cgaaagttcc agcattacca cacagagaag tatgttgcgt ttatatgcaa aagaacatca
     3961 tttgaatgtc attgatgaat atattgatga cggctggtcg ggaacaaatt ttgacagacc
     4021 gagttttcaa agaatgattg aggatataga ggcaggaaaa atcaactgtg ttgtaacgaa
     4081 agacctttcc cgtcttggca gaaattatat tatgacagga caatatacag aattgtattt
     4141 ccctagtcat aatgtccgct acatagcgat tgatgacggt gtagacagcg aaaaaggcga
     4201 aagtgagatt gcaccattta agaacatcat caatgaatgg gtggcaagag atacaagccg
     4261 taaagtcaaa tcagcattta agacaaagtt tgcggagggg gctcattacg gtgcttatgc
     4321 tccgttagga tataagaaac accctgacat caaaggaaaa ctgttggttg atgatgaaac
     4381 aaaatggatt attgaaaaaa tcttttccct agcctatcaa ggttacggaa gtgcaaaaat
     4441 cacaaagcag ttaagagcag aaaaagttcc gacagcgtca tggctaaatt ttacaagata
     4501 cggtactttt gcacatatct ttgagggaaa acccgaaagt aagcgttatg agtggacgat
     4561 tgctcatgtc aaggcgatat tgaaaagtga ggtttatatc ggaaacagtg ttcacaatat
     4621 gcagtctacg gtatcgttca agagcaaaaa gaaagtgcgt aagcccgaaa gtgaatggtt
     4681 tcgagtagaa aacactcacg agccgattat tgacaaggaa gtgttctatc gtgtgcagga
     4741 gcagataaaa tcaagacgca gacagacaaa ggaaaaggca acgccgattt ttgcagggct
     4801 tgtcaagtgt gcggattgtg gttggtctat gagatttgga acgaataaga caaataaaac
     4861 gccttacagt tattatgctt gcagttacta cgggcagttt ggcaaaggta attgttctat
     4921 gcactacatt cgttatgatg tgctgtatca agccgtattg gaacgcttgc agtattgggc
     4981 taaggcagta cagcaggacg aagaaaaggt attgaacaag atacagaaag ctggcaatgc
     5041 agagagaata cgggaaaaga agaaaaaggc aagtacattg aagaaagccg agaacagaca
     5101 aaatgagatt gaccgtttat ttgcgaaaat gtatgaagat agagcctgtg agaagataac
     5161 agagcgaaat tttgtgatgt tgtccagcaa gtaccaaaaa gaacagatag aactggaaca
     5221 gcagataaca agcctaagag aagaactaag taaaatggaa caggatatga taggtgctga
     5281 aaagtggatt gagttaatca aggaatattc cgtaccaaag gaactgacag caccattatt
     5341 aaatgccatg atagaaaaaa tcctcataca tgaagcaaca acgaatgagg ataacgaaag
     5401 aatacaggaa attgagatat attaccgatt tattggaaga gttgagtaat caacaagagt
     5461 aatattttta actaagggaa accggcggtg tctatacttg ggtcagtcgc acattgggaa
     5521 aacgattcgg ttttgccgca atctttttcc aatggtttga gataacagtt ggctacttga
     5581 ccatgctgta tttcttaact ggtgcattat cctatgcaac gggtattggt gctatacaaa
     5641 acaataaata tctgaaattg gcaatcctat tgattatttt ctgggctatt ttactctcac
     5701 agttaaaagg aaccaaatac acttcattga ttgctcggat cggttttgta gctggtatct
     5761 tgttgccagc attagtcttg tttggcttag ggatccatta tgtcgcttca ggcgctccac
     5821 tacaaacgat actgtctatg aaaacattga ttcctgattt ttcgaaattg cctacgctgg
     5881 ttgtttttgt ttcctttatt ttagcatata tgggcgtaga aacatctgcc agtcatgcaa
     5941 atgaaatgga aaaccctaaa aaggattatc cattagcaat gtttgtattg gttattctgg
     6001 caatcatttt agatactttt ggcggattga ccgtcgctac tacagtacct caacatggtt
     6061 tgtctcttaa tacaggggtg attcaatcgt tagaattcct attaagacac attgatccaa
     6121 atcttgcatg gattgcgaaa attcttgcga ttcttgtttg tttaggtgtc atcggagaaa
     6181 ttgcttcttg ggtaacctct ccttcaaaag cacttcacgt agcagcagaa gaaggattac
     6241 ttcctgaata ttttgcaaaa gaaaacacac acggtgttcc tgctcatttg atgatcgcaa
     6301 atgggatcgt tgcaacaatc tgggcagccg tctttacatt aagcggcggg gggaataatc
     6361 tttcatttct tgcagcgatg tcattgactg ttgtaatcta cctgatgttg tactttatgt
     6421 ttttcgcggg ctatttgaag ctggttttta aagatgacag tcttgaaaga gcctatcagg
     6481 ttccaggcgg aaaagttgta aaagtaatcg ttgcttgttt aggtcttttg acttcacttt
     6541 ttgctttttg tatctcattt gttccacctg ctagtatcgc agctggacag catgggattt
     6601 atgaaacgat tctgattgtt tcttatctta tcgtcttagt tattccattt acgatctacg
     6661 catgccgtca taaattccag catgcagaaa aataaaaaat gaaagctggt tattcaaatg
     6721 gaagtaaaag aattagaaca attgattgga aaaaatttcc actattatca aacaggacaa
     6781 gtggcggatt acattccagc attagctgaa gtggatccca aacaattagg tatggcgatt
     6841 tatgatttgg atacaaaaca actgattgag ggaggagacg ccgatgtgcg ctttgccatc
     6901 gaaagcatgt caaaagttcc cgtattgtta ttagcaatca aagacaacgg aatagaaaaa
     6961 gtctttcaaa caatcaacac ggaaccaacc ggttttgcct tcaattctat catgaatatg
     7021 gaaatcaatc atcgcaaaca tccaatgaat ccttttgtta atgcaggagc gattgcaaca
     7081 acctcgttga ttgccggtaa agatgcagat gaaaaatttg agcgaatctt gtcatttatg
     7141 aaagagatct gtgatgatcc taatatcaca ttgaatgaag aaatctatca ttctgaatca
     7201 agaacaggtg atatcaatcg ctctcttgct tactatatga aaggtaatca aatgatcgaa
     7261 ggagacgtac cggagatact cgatgcttat ttcagacaat gctccctcaa tgtcaccgct
     7321 acaggcatag caaaattagc tgctgtgctg gcaaataaag gaattgctcc ttggaatggc
     7381 aaacaaatca ttactgaaga aagtgctaca atcgtcaaat caattatgac aactgctggt
     7441 ttgtatgatg aatcaggaga gttttccgtc catgttggtg tacctgcaaa aagcggtgta
     7501 ggcggcgggt tgatggcagc tgtgccaaat cgttacggca taggtgtctt cagcccggca
     7561 ctagatccat ttggtaacag cgcagctggt atccaattgt tgaaagatgt agtcaaagaa
     7621 ctagacgctg acatctttga ataaccattc ttgaaagagg ctggggtaaa agtccaaacg
     7681 gctcaaagct acctacaatg aggctgaaat tgtgagcttg tttgactttt gtcccagttt
     7741 ctttttttat tggtttttga aagggctttt ctaaataaaa aggaaacaaa aatacgattt
     7801 acagatatga ttaaataaaa tcataagaaa aactggaggc gtgtatcagg aatgctggaa
     7861 aattacatcg agcgaaatat atttagaaaa gtgtatctgt gtgaacaatt atttgaattc
     7921 caagaaatag acatcgaaca aacagctatt tctctaaggg tgactacacc aacgatcctt
     7981 cacgatctag aaagtctagc cgagtgtcta gaatattgta taaaagaaca agtaagagag
     8041 aagcataagt ataaactcgt attcaaacat ggtattgctc tttctgagct cacacagttt
     8101 ctgtacggtc aatcttattt tttaaagttt ttaagttatt attttaatgg tatattcacg
     8161 agtacagaac tggctgatct tgaatttatt tctttgagta aagtatatac aatcaaaaaa
     8221 atcgtattgg atttttttaa agaaaatgat tatttgaaaa ataaagaaat cattatccca
     8281 gaatttgact cgcggaacat cttgctagct ttagtacgtt atgtcaattg ggaaggctat
     8341 gaaaataaaa atccgtatgt agaagaagct tgtaacgagt tgattgatta tgtagagact
     8401 cattttttta aaagaagata ttcggaagat gaaaagtcct ttatcatacg agaaatagag
     8461 atcgcaatcg gaagaaaggc atttcccctt ggactgaaag aagaagataa gaaaagcgca
     8521 gaaacgaagc cgttatttca attagtctgt caaggattgg aagagcaaaa aggaattcta
     8581 gacttacaag aagaagatgt ctattatatt ttttctttgt tcaacagtag aaattatacc
     8641 aatgagaaca tggagctgtt aagaaaagat ttcgaagttg tttataaaaa ttttgttctc
     8701 aatgacctat cactgaatga attgatttta cagattatta gtatcgctga aatcgacgat
     8761 gcagaaaatt ttattttcaa gcaatccttt ttacaatttg tccgtacgtt gtgggcagat
     8821 ggacaagtat ttttaccgga aaggatctat cttctatcag aaaaagaaca acttctgtac
     8881 ggaaaaattg tagaaatatt ggaagagtgg aaaaagaaaa atcaaatcca actaagatgg
     8941 aatgaaaatt tcattcgaaa attcgtcaaa agtctttctt tgatcaacag tgaacaagcg
     9001 gggagacagg aaatagaaat ttttgttgtt tcagaaagtt cagtcaaaca atttttttat
     9061 cgaacccaat ttcatttgta tgcggaagaa ggcatcgctg aaataaatcc tattttattt
     9121 cgttcattag aagaattgcc tgatgaatgt ctatgtgcga aaaaaagagt ggttttgtgc
     9181 gatgctgcta gctatcaaaa tggattagaa actgaaaaga caaagatcta tccaatctca
     9241 ttaaaaggtg caaacatcca tttgtatcat attgctcagg aacttcacct attaaaaaaa
     9301 catatttctt gatgagacct taattaggag accttctaca aagcttttta attgtctgta
     9361 gaaggttttt atttgagtcc tgattcgtgc gaagatctac ttatataaca agctttctct
     9421 gaaatttttt taaaatgcta ttgacttaga gtcaactcta agtagtagaa tagataaagt
     9481 gtaacaaatc tattttcatt aaaagaagat agtacggagg agagaatgta ttatgagtac
     9541 agtattacat gtattggatg caatcaatag ccccgcagat gtcaaaaaat tatctgttga
     9601 ggaaatgaaa cagttggcag aagagatgcg ccaaaaaatc ttgcaaaagg acagcgatgt
     9661 aggtgggcac gttggtccga atctaggtgt agtagaatta acgattgcgt ttcattatgt
     9721 atttgattca ccaaaggata aaatcgtttg ggatgtttcc catcagtctt atggtcataa
     9781 gcttttaact ggtcgaaaaa atggttttga aaaaggacat taccgtgaag tgagcggata
     9841 ttccaaccaa catgaaagta aacatgacta ttttacagtg gggcacacat ctacatctat
     9901 cagcttagca acaggtttag ctaaagcgag agatctgaag aaagaatcag gaaatgtggt
     9961 agcatttatc ggtgacggct ccctaagtgg tggcttagct tttgaaggat tgaacaatgg
    10021 tggtgtttta caatccaatc taatcgtatt agtaaacgat aatgagatgt ctattgatga
    10081 gaatcatggc agtttatata aaaacttagc tgagcttcgt caaaccaacg gtaaaagcag
    10141 caataaccta tttaaagcaa tgggatttga ttatcgttac gtggataatg gaaacgatct
    10201 ggaaacggtg atccgtttat ttgaagaagt aaaagatatt gatcatccga ttgtacttca
    10261 cgtccatacg gaaaaaggtc gcggttatca gccggcaatc gataataaaa tgaaatatca
    10321 ttggcatgta ccatttgatc tgtccaccgg ggaggcaaag caagtaactt ctggagaaac
    10381 atttaatatg atcatcatgg attatttgga taagaaaatg caaacaagta cagctcctat
    10441 tgccgcagtc aatgcagcga taccaggcgc ctttggactg aaaacattcc aagaaaaaca
    10501 tccagatcat tattttgacg tggggatcgc tgaacagcac tctatcactt tcgcttctgc
    10561 tttggcttct cagggagtac gtccagtcgt cttccaatca agtactttct tgcaacgggc
    10621 atatgatcaa ttatcacatg atttagcgat caacgagaat ccagtgatta ttttagtcgg
    10681 tggcggaacg atctcagcta gtgaccgaac acaccaagga acatttgaca ttccttactt
    10741 atcaagtatc ccgaacatca aatatcttgc tccagcaaca aaagaggata tgatctctat
    10801 gctagattgg gcgttcgaac aaacagcgca gcctgtagca atccgaattc ctacacatgg
    10861 tgtagaacat ggtacagcta tcgcaaatga ttatagtatt ccagcctatc aaacagtaaa
    10921 taatggagga aaagtagcaa ttttagcttt aggcggtttt cttgaattag gaaaagaaac
    10981 agtaaaagct tttagaaaaa aaggaatcga agcaacgttg atcaatccag gaacgatcac
    11041 agaaaatgac gtagaaacat tagataaatt aaaagaaaca cacgaattag tcatcacatt
    11101 agaagatggt agtttgtcag gaggatttgg cgaaaatatc agtcgttatt atggtgattc
    11161 ttcaatgaac gtattaaatt ttggtgcaga gaaagaattc acggatagcg ttcctgtagg
    11221 gcagctttat gaacgttatc atttaacacc aaaacaaatc gttgaagata gtctgcgtgt
    11281 cttgaatatt caataattca ttatgctcac catccagata attgtttata ctagtatctg
    11341 gatggttttt tcattataaa aagcaaaggg gtggatgtta tgtatcagca agtagaagaa
    11401 tatgtcaaaa agttccaaga aaaatatcct agttatcaat cagaaaaatt aggtttcttt
    11461 tcatttgggg atacagaaaa aatggcagac gagttgagcg aactagttgt aaaaaagata
    11521 aagactggta catcaagtgg ttacgatctg tataaacaag agaatgagcc tttaccaaaa
    11581 gttggtcaat tagacgtggt cctgaatgga aaaaatgaac cagtttgtat catcaaaaat
    11641 ataaatgtga ccatcttgcc ttttagtgaa gtcacgaaag agcatgcttg gaaagaagga
    11701 gaaggggatc ggacattagc ttattggcgg aaagtccatg ctgagttttt taaacatgct
    11761 tataaagaag cgttgaacat agaatttaca gaagagaagc tggtcgtata cgaagaattt
    11821 gaagtaattt tcttttagta agaaaggtct gctgaaagaa atagctcatt attgtctcct
    11881 gaatagaaaa gggttacatt tttatatgaa gctgtatttt tatataacat tactggagga
    11941 gatattgtgg atacactgga acaaatcaaa ggcggagtcg tcgtttcttg tcaagctttg
    12001 gaaaacgagc cgctacacag ttcttttatt atggggagaa tggctttggc tgcaaaagaa
    12061 ggcggagcag ttggtattcg agcaaatacg acagaagata tcaatgaaat caagcgaatc
    12121 gttgatttac cggtaatagg gattatcaaa agagattacg atgggtcaga agtgtttatt
    12181 actgcgacag aaaaagaagt ggaagaactt ttggagacgc aagcagaaat cattgcactg
    12241 gatgcaactt ctcgtaaacg tccgacagaa aaaacaactg ctgaacttgt ccaaatgatt
    12301 cacgaacacg gtcggttagc tatggcagat atttcgactt ttgaggaagc gcttcaagcg
    12361 caagaagatg gttttgatct tttgtctacg actttagcag gctatacaga atattcacga
    12421 aagacgcaga cacctgattt tgatttattg aatcaaatca tagaacaagt cgatatccca
    12481 gtaattatgg aaggacatac tgactctcct gaacaagtag agaaagcata tgaattaggt
    12541 gctttttcag tcgtagttgg atctattatc acccgtccgc aattgatcac taaaagatat
    12601 gtcgaagccg caagtaaagc aaataactaa aaaacacgca cggcacagat tcttgacaaa
    12661 aaagaaaaat tgatagatag tttaaagcag attctaagaa gatgaaaaaa gcattacttt
    12721 tcattttgtc ttcaagatct gctttttaac gaattttata gaaagaaggc gaaaccatgt
    12781 ttgaacggag tccttcagaa ttgacagaac gtgaaaatta caagttgctg attggttcag
    12841 tcatccctag accagtagca gtagtaacga ctaaatcagc aaaagatata gtgaatatcg
    12901 cacccttcag ttacttcaat atcgtcagtt cgaatcgacc catcttatcc ttggcgatcc
    12961 agagaaaaca agatgcagta aaagacacag caaagaatat tcttgagaca agagaagctg
    13021 ttatccatat ccttgatgag gacaacgtag aagaagtaaa taaaacagca gccaatctgc
    13081 ctaatgagga aagcgaactg tacctgactg acttgacttt aactgattca gtaatcattt
    13141 cagtaccagc attgacagaa gcaaaagttc gttttgaaac atccttatat gaacatgtcg
    13201 agatacggaa taaaaataaa gtaacagctg atttattttt gctagaagta cagaaatatc
    13261 atttaaatga aacagtctat gatgataaga caggaaggat cgatccaaga aaattgaatg
    13321 ctgtaagccg tttggcagga aatgattatg cagcaatagg agaaattttc acgattgcac
    13381 gtcccgaata aaaaggagca ctagttatgt taaaaataag ctataaacca tcgacagatt
    13441 caaaagaaat gaaaaaagaa tatgaaacag tgaatgattt tctgcaaggg cagtacttag
    13501 aagttccgcc attgcaagac cattttgtcg ttactactgt tactttagat ggtaaggaaa
    13561 tagaaatg
//
LOCUS       DACGEU010000073        13480 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.073, whole genome shotgun sequence.
ACCESSION   DACGEU010000073 DACGEU010000000
VERSION     DACGEU010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13480
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.073"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(60..1613)
                     /locus_tag="IXR40_002069"
     CDS             complement(60..1613)
                     /locus_tag="IXR40_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAQ4361901.1"
                     /translation="MQTQEAIKTFLLKKKSNTKLDIFLFLSEHRFFITTQYLADHFHM
                     SESNFLLYIKELEQDFERLNLTELHIDKQKPFLKLNFEGIDPAYCYYRLFGRYCNESV
                     SYQILTSLFSCQTNSIISLSQQTNYSASYLYTKMKKINAFLALYGLSISFSNNGRKSF
                     SGKEVQIQYAALDIYWNIFSSTATEFYDEDPQVVAFMMNTFFKKEVLDRLNSGMIDKL
                     YFLLKICKENFPATSVKDVQKEFTEYEYIDFFIDPSVDILRPNLPICREQRILVNILA
                     RLSITKIESEETSLEQYKLLKKANVPHVLYSREMVESFCTVFDLFIPEKEKILYSLAF
                     ARNKLYNGFLNFNQPNTPLPTFMLYQEHSVLKEVQTAIEQFYMDFREQNQHLLPVILE
                     KENVQWMVEDLVHLYDRYKKQPRIVIGVNYTRDFYISKDLIVKIEQIFSNESIKIQND
                     FMENCNIVISDCPLKQLPSHIKKIYILKGIITPEDWKKVIMRISEYIFELKEEALMDQ
                     SKKENQVTS"
     gene            1761..3050
                     /locus_tag="IXR40_002070"
     CDS             1761..3050
                     /locus_tag="IXR40_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAQ4361902.1"
                     /translation="MRYSTILISTFAALSLSLTINQTVHTEEIETAKWTETKWANVNR
                     ITFQDEFSSFNSGVAKLRKGQTATIKAKIDYSGDLAPILQSAVTFENVDPALSIGYDE
                     NTLTIQHKQAIFTFTVTLNQDLLKPALFTVKVSDGLPNDHHHLTPYSQRQTIEQDSAI
                     DSGGDLVEEPTDKPENENKPEVPPTENPDGEQKPEIEPGEEPDTETQPEPDNESKPEI
                     TPGEKPDVDPEEKPDVTPEPDTDSGNQTVPETNPDTDNETENPEKPEVAPEEKPDVTP
                     EPDTDSGNQTVPETNPDTDNETENPEKLEVDPEEKPDVTPEPDTDARDQGIPEKINKK
                     TIQEDGKKESKKSNLAILKINEEQLNKKSRIFDSAQSAETLKSSKDTTFASPETKNKQ
                     LPKSGESQNKVILWSGIILLSIATMLSAKRFKQNRSL"
     gene            complement(3176..4255)
                     /locus_tag="IXR40_002071"
     CDS             complement(3176..4255)
                     /locus_tag="IXR40_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAQ4361903.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVIDFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVIALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(4364..4804)
                     /locus_tag="IXR40_002072"
     CDS             complement(4364..4804)
                     /locus_tag="IXR40_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAQ4361904.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTSLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTPQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(4861..5271)
                     /locus_tag="IXR40_002073"
     CDS             complement(4861..5271)
                     /locus_tag="IXR40_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HAQ4361905.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(5452..5886)
                     /locus_tag="IXR40_002074"
     CDS             complement(5452..5886)
                     /locus_tag="IXR40_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HAQ4361906.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVSFEERKQLFEKYM"
     gene            complement(5986..6834)
                     /locus_tag="IXR40_002075"
     CDS             complement(5986..6834)
                     /locus_tag="IXR40_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAQ4361907.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAVLGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLFFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFVFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            7223..8989
                     /locus_tag="IXR40_002076"
     CDS             7223..8989
                     /locus_tag="IXR40_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HAQ4361908.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETRRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVRDHLDYLTDLGVNGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVYDREDKLYFTRELEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            9091..10350
                     /locus_tag="IXR40_002077"
     CDS             9091..10350
                     /locus_tag="IXR40_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAQ4361909.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            10497..11798
                     /locus_tag="IXR40_002078"
     CDS             10497..11798
                     /locus_tag="IXR40_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAQ4361910.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            11801..12652
                     /locus_tag="IXR40_002079"
     CDS             11801..12652
                     /locus_tag="IXR40_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAQ4361911.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            12665..13480
                     /locus_tag="IXR40_002080"
     CDS             12665..13480
                     /locus_tag="IXR40_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HAQ4361912.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
BASE COUNT         4562 a         2413 c         2476 g         4029 t
ORIGIN      
        1 cttgatacat aaatccggag gttgttaata agcattcgga tttatgtatc ttatttggtc
       61 taggaagtaa cttgattttc ttttttcgat tgatccatga gtgcttcttc ttttaattca
      121 aagatatatt ctgagatcct cataatcact tttttccagt cttctggtgt gatgattcct
      181 tttaaaatat agattttttt gatatgagaa ggcaattgtt tcaaagggca gtcgctgata
      241 acgatgttgc agttctccat aaaatcattt tgtattttga tcgattcatt tgaaaaaatt
      301 tgttctatct taacgatcag atctttactg atataaaaat cacgcgtata gttcacacca
      361 atcacaattc gcggctgttt tttgtagcga tcatacaaat gtactaggtc ttcaaccatc
      421 cattgcacat tttccttttc taaaataact ggtaacaagt gttgattttg ttctctgaaa
      481 tccatataaa attgttcaat ggcggtttgg acttctttca acacgctatg ttcttgataa
      541 agcatgaaag taggaagggg cgtatttggt tgattgaagt taagaaatcc attataaagt
      601 ttatttcgtg cgaatgccaa tgagtaaaga atcttttctt tttcaggtat aaacaaatca
      661 aatacagtac aaaaggactc caccatttct cttgaataaa gaacatgagg aacgtttgct
      721 ttttttaaaa gtttgtattg ctccaagctt gtttcttccg attcgatttt cgtgatagaa
      781 agtcgagcta aaatattcac taagatgcgt tgttcgcgac aaattggcag attaggtcgc
      841 aaaatatcta cagagggatc aataaaaaag tcaatatatt catactctgt gaattctttt
      901 tgtacgtctt tcacagaagt tgcaggaaaa ttctctttac atatttttaa tagaaaatat
      961 aatttatcta tcataccgct atttagtcgg tcaagtactt cttttttaaa aaaagtattc
     1021 atcataaaag ccactacttg cggatcttca tcataaaatt ctgtagcagt acttgaaaag
     1081 atgttccaat aaatatctaa tgctgcatat tgaatttgta cctcttttcc agaaaaagac
     1141 tttctgccat tattagaaaa ggagatagac aaaccgtaca atgctaaaaa tgcattaatc
     1201 tttttcattt tcgtatacaa ataagaggca ctatagtttg tttgctgact taaactgata
     1261 atcgaatttg tctgacagct gaacaaagaa gtcaagatct gataactgac tgattcgttg
     1321 cagtatcttc caaatagacg ataatagcag taagccggat caattccttc aaaattcaac
     1381 tttaaaaaag gtttttgctt atcaatatgc agttctgtta gattgagacg ctcaaagtct
     1441 tgttctaatt ctttgatgta tagtaaaaaa tttgattcag acatatggaa atgatctgct
     1501 aaatattgtg tagtaataaa gaaacgatgt tcagatagga aaagaaaaat atctaatttt
     1561 gtattgcttt ttttcttcaa gagaaacgtt ttaatcgctt cttgagtttg catgaaagag
     1621 gctccttttt acttaaattg ttaaaacttg aaaatattac tgtttttttc ataaatttag
     1681 acaaaaaaac agtaaacata taggtagaat ctctactatc ttatttcttg catacaaaaa
     1741 aatcaaggag tgagagagtt atgagatatt caaccatctt aatatcaaca tttgcagcct
     1801 taagcttatc gcttactata aatcagacag tccacacaga ggagatagaa acagccaaat
     1861 ggacagaaac caagtgggcc aacgtcaatc gaattacctt tcaggatgaa ttttcatcct
     1921 tcaattcagg agtcgcaaaa ttaagaaaag gacaaacagc gaccatcaaa gcaaaaattg
     1981 actattcagg agacttagca cctatactac aatcagctgt tacatttgag aatgttgatc
     2041 ccgctttgtc gattggctat gacgagaaca ctttgactat ccaacacaag caagcgatat
     2101 ttaccttcac cgttacatta aatcaggact tgttaaaacc agcgcttttt actgtcaagg
     2161 tatcagatgg actaccgaac gatcatcatc atttaacgcc gtatagtcag cggcagacaa
     2221 ttgagcaaga ttcagctatc gactcaggag gagatcttgt tgaagaacca acagataaac
     2281 cagaaaatga aaataagcca gaagtaccgc ctacagaaaa tccagacgga gaacagaaac
     2341 cggaaataga acctggagaa gaacccgata cagaaactca accagagcca gacaatgaat
     2401 caaaacctga aataacccct ggagaaaaac cagatgtaga cccagaagaa aaaccggatg
     2461 tgactccaga accagatacg gattctggaa accaaacagt accggaaaca aatccagaca
     2521 cagataatga aactgaaaat ccagaaaaac cagaggtagc cccagaagaa aaaccagatg
     2581 taactccaga accagatacg gattctggaa accaaacagt accggaaaca aatccagaca
     2641 cagataatga aactgaaaat ccagaaaaac tagaggtaga tccagaagaa aaaccagatg
     2701 tgactccaga accagatacg gacgcaagag accaaggaat accagaaaaa ataaacaaaa
     2761 aaacaattca agaggatgga aaaaaagaga gtaaaaaatc aaatctagca attctaaaaa
     2821 taaatgaaga gcagctgaat aaaaaatcac gaatatttga tagcgcccaa tcagctgaaa
     2881 ccttaaaaag tagcaaggat acaacctttg ctagtcctga aacgaaaaat aaacagctac
     2941 caaaatccgg agagtcacaa aacaaagtta tactgtggag cggaatcatt ctattaagta
     3001 tagcaacaat gctttctgca aaaagattta aacaaaacag atctctctaa catttgaata
     3061 atgtctgtga acgcattttt caaataaaaa gaaatatcca gaaaacgacc ccaaaatacc
     3121 agattgaaat ctgatatttg gggtcgttca tactttatct ttcttcatat ttattttaag
     3181 ggatatctgt ttcttttgga agatggttcg ggatcttttt cactttcaat acatctaaaa
     3241 agaaggtaaa gatcggaatg ccgacaatca agccccaaac gccaaagaac cgttcgctaa
     3301 caagtaagac cacaaatgta taaaaaatcg gcagttctgt tttgctggac atcaacttcg
     3361 gattcagcac ataagactca attagatgga caatcaaaat cgtaatcagg atataaacaa
     3421 catctcggat gcctccttgg gaataagcta tgaaagatag aggaatacaa gaaatgataa
     3481 cacctgctac tgggatcaga cttaaaatga aaatcatgat cgctaaactc agcagctgat
     3541 gaaagccaaa tacagccaag gcgattgtag tgagcaacgt gtttaaaaga gcgataacaa
     3601 attgagcttc taataccaaa ccaaatgtat tgacaaactt atcggcaaaa tagtaaatat
     3661 cttgaaagaa ccaagaaaat tcacttttta aaaacaatct tgagaataca attgtttttt
     3721 tcttttcaat cataaaaaag aaacttaaga tgaatgacat agcaaacgcc actgccattt
     3781 ttcctatatc ctgtaaatag ccaagcgcaa tcgaagcgcc attttgaagc tgttcaaaaa
     3841 aatcgtttcg ctcaatataa gtatggatat attgtaaaac aggatctgca tcttttggct
     3901 gatgctcgta aaaatcaata acggactgga tcatatcaaa tgtttgatga ataagcatcg
     3961 ggatatactt tgtgaatgcc agatagataa ggtaaacgat cagtgtataa atcatgatag
     4021 ctaaaacacc tgtagggatt cggacaaatc gctgaatgat ttgaacaaga tgaatcatca
     4081 aataagtaaa gataaatgtg agcaaaatgg ttgtaatcat acttctaact aagaaaagaa
     4141 caaaaacgac aaataataaa acagtgagac ggcgtatttt ttcattcgcc aaaaaacgct
     4201 gataaacggt caaatcgaca acctccaaat aacaaaaaat aaacacgtta ttcattatat
     4261 gatggaatat gaaaataaga aagagaaaga gcaaaaagaa aaaccgctaa atgacgttat
     4321 cttatgagtt ggttttcctc ataaaatcgt tcatctagca gtttcagccc tttttctggt
     4381 cttgatgaaa attatctagc atttttcggg tcagatgttg cagtgtatcc aattcttcct
     4441 gttcaagtgg aagataagac ttgatctttt gtggaatacc ttctgcttgt ttttgcaacg
     4501 cagcaccttg aggagtcagc gtaacattta cgattctttc atcacccgtt tcacgctgac
     4561 gattaatata atttttttct gctaactttt ttagtaaggg agtcagcgta ccagaatcca
     4621 gacacaaatc atttcctagc tctttcactg aagtcttttt cttttcccat aaaactaaca
     4681 tcacaagata ctgggtatag gtaagattca gcggcttgag gagggaagtg tagtgtctaa
     4741 tgatttcctt agaggcggca tataaaggaa aacatacttg attaactaaa tatagatctt
     4801 ccatttttcc acctccgctg ttttactata gtgtatcata gcggatttac acaaaaaagt
     4861 ctattcacta actgctttca gagtaacttc tatatttcca gctgtagctt ttgaatacgg
     4921 acacacttta tgcgctgcct ctaataattc ttgcgtttct tccagagaaa gaccttcgat
     4981 agatccttca atctctacac ctaagacaaa gctcgtttca ctttctgaat aaagggaaac
     5041 ttgtgcactg acagtagaag ccccagagat atttttttgc tgtttgatca attctaatgc
     5101 actgttaaaa catgcactga aaccagctgc aaacaattgt tcagggttgg ttgcattttc
     5161 gacgcgttta ccaggagctg caatattcaa ttcgaatgta cgatcgggat tatgaacttc
     5221 tccagagcgt ccgcctgtgt tgatcatttt cgtagaatac atttttttca taaaattacc
     5281 acctttaatt atattttata caattgaatt ttacacaata taattgtgga aagcaaagaa
     5341 atggattggc ataagataaa taagagaaag cacatgaaac agacgcgctt tctcgaatag
     5401 caaacatata caaaaaaata tcagagacaa aaactaatct catcataaac attacatata
     5461 tttctcaaaa agttgttttc tttcttcaaa acttacttca cgatggacct gatgaagcat
     5521 ccataaataa ccaaaaggat ctctgaacat tgagttagtc acaccaaagt ccatcatttc
     5581 tgtcatttct tgaatctcta cacagccatt tcgtaatgct ttattatgtg tgtcctcgat
     5641 atcagagacg atgatattga accagatcgt atttggatgt tcagcagtag gagcagtcaa
     5701 accaagagac gtgttttcat ccagcatatg gaatctcgtg ccatacaagg taaaaatgac
     5761 ttcattattg cctctagggt aatctgttgc ctcaatcagt tgtatttcat caaagattgt
     5821 ttgatacagt tctagtgctt tcaaactatc atttaataca aaatctattt ccgttccttt
     5881 atgcataaag atctcctctc cttttcagtc gaacagttac tagattcttt tattatacca
     5941 gttaaagaaa acgcattcaa aaaaatagcg gatttactta ccaactcatt cgattggatg
     6001 ataagtaaat ccgcgtccca ttacttctgc tacgctgctg acaatgacaa aggcacttgg
     6061 atcgatttct tctatcaatg gtttcattcg ggaaaattca tgatcagtca caacgatcaa
     6121 taaaacctct tttgactttc gattataccc gccttttgcc tctagcaggg taaggccacg
     6181 tccaatctca gcacttaagc gaaggcggat gtcttccaaa taatgttcac tcatgaccat
     6241 aacagatttc tttcgattga tacctgtttc gatataagtc atgacaattg aagtgattgc
     6301 aatagataaa atagcataaa gaaactcttc tattccaaaa acaaacagat taagagaaac
     6361 aacgaatgcg tctgtaaaaa ataagccaat cgaagtattc aagtggaaat attttttaaa
     6421 aatgagggga gggatcgtcg taccgccgct agaagagttg tttttatata aaatcgcaac
     6481 tcctaaagca aaaatcgcac ttccaaaaat gacagacaac aaccgatctg aagtaatcat
     6541 tgtttctgga actattgcaa tgattaaagg aaaaaacaag cttccgaaaa gtactttaaa
     6601 aaagggtttt ttacctaaaa atagaagagc tagtaccaac ataacgatat tcaacactaa
     6661 aataactata gctcggtcaa atcctaaaac agcttccagt aatattccta gaccgctgac
     6721 acctccagca gcaatatgat gaggccctaa aaacatattg atagcgactc ctaatatgaa
     6781 gagggcaaaa ataatcttaa tgtatgtcca tataaattgt ctcgtttctt tcatttatcc
     6841 acttccttaa ttcattaata atactcttat cttattataa cttacttttc accttaagtt
     6901 aactttaatt aataaaaaaa ttaggctagt ctaaattatt atgtttcatt cttctagaat
     6961 atacttctac gttaaaaact gttaaaaaac ttttacttta gaaaattgga gaaattgatc
     7021 gcttaagata aattcaggac actaaatagt acaggaagta gattaaaact tttaaaagtt
     7081 ttaagtctat ctatttggca agtttaaaaa ataaaaattc ggtatcaaaa aactgttacc
     7141 gataacattt ttgaaagcgt tgtcttttgt ttctctatca cttatagtga tgacgtcata
     7201 ttaaaacaca aggaggaaat caatggatac agctgcaatt tatcatcgac cggaaagtga
     7261 atatgcattt ctatatacga atacaagatt tcgtattcgg cttcgtacta ggaaaaatga
     7321 tatcaaaaaa gtatatgtgc tttgtggaga tccatatacc ataacaactg aaaaatggta
     7381 tcaaaaacaa cgaccaatga aaaaatgtct aagtaccaat gttcatgatt attgggaaat
     7441 tgaagtgacg agcgaaacaa ggcgcttaca gtatgcgttc catgttgttg gggaagataa
     7501 cacggactgt ttttacggtg atcaaggaat ttttccttat cgagaaaatg tgattactga
     7561 accaaatttt tattttcgaa taccttattt tcatcaaatc gatcgattca ctattccaga
     7621 atgggtaaaa gaaacagtat ggtatcaaat ttttcccgaa agatttgcaa acggggacaa
     7681 agcaaatgac cccgaacaca ctttaccttg gggaagtaaa gatccagacc gagaagactt
     7741 cttcggggga gatttgcaag gtgtgaggga tcatttggat tacttgacgg accttggcgt
     7801 caatggcatc tatttttgtc ccatatttaa agccacatcc aatcataaat acgatacgat
     7861 tgattattat gaggtggatc ccgcttttgg cgataaaaaa cttttaaaaa acttgattga
     7921 tgaagcacat aaaagaggga tacgtatcat gttcgatgct gtattcaatc atatgggtgt
     7981 ccattcacca cagtggcaag acgttctcaa aaacggagaa aaatcgatct ataaagactg
     8041 gttccacatc cgttttttcc cagtagattc ttatcagatg actgacttac cagaaactgc
     8101 tgaaaatatc ccatatgata cttttgcttt tactccattc atgccgaaac taaatacagc
     8161 aaatccagaa gtgcaaaaat atttgctgga tatcgcaact tattggataa aagaattcga
     8221 tattgatgga tggcgtcttg atgttgctaa tgaagtcgat catcattttt ggaaaaaatt
     8281 cagagaagca gttacagaaa tcaaaccaga catctatatc cttggagaga tttggcattc
     8341 ctctcaagct tggctgcaag gggatgaatt ccatgcagtg atgaattatg cattcacaga
     8401 ttcgattaaa gattattttg caaaaaagaa aatcacagct tcacaaatgg tcagtggaat
     8461 gaatcatcag caaatgcttt acagagatca ggtgaacgaa ggaacattca acttattaga
     8521 ttctcatgat actgccagga tcttgaccct ttgccaaggt aacaaagaat tgatgaagtc
     8581 tgtgatggcc tttatgtttc ttcaaaaagg gtctccttgt atctattacg ggacagaaat
     8641 agggatgact ggtgaagatg acccggattg ccgcaaatgt atgatatggg agaaggagga
     8701 acaagatcta gagctattcg gttttataaa agaacttgtt tctctaagga aacagttgtc
     8761 taagattatt tctgaaggtt ctactcagtg gctaatagta tatgatcgtg aagataagct
     8821 ctatttcaca cgggaactag agggacagat catctatgtt tactttaatc agtcaaaaga
     8881 accttgggta gtagaacagg aaaatgaggt gattcttagt caaaattgtc agttgttaga
     8941 agacgggaaa gcagagatac gacaatacgg atttttgatc atgtgttgaa aactgttacc
     9001 ggtaacaaca agaaagcgtt tgcaaatgaa gatttgtgcc cattataata agggtgtaac
     9061 agcacgttga atacacagga ggaaatgaag atgaaaaaaa gaagtgtgaa acagttgggt
     9121 ttagggttaa tctctttagg aatcttaggc ggattagcgg cttgtggcaa tggtaactct
     9181 tcagcagaag gggaagccga tgaaggaaaa acgttaacag tttccgttga ttctggatat
     9241 aaagattata taaacgaaat aaaaaacact ttcgaaaaag aaaacgatgt gaaaatcaag
     9301 ctagtagaaa aggacatgtt cgatcagttg gaatcattag cgttagatgg gcctgctgga
     9361 aagggacctg acgttatgat ggcagcatat gaccggatcg gtgcgttagg acagcaagga
     9421 catctggcgg aagtaaaact gggaaatgaa gcagcttacg atgaaacaga caaagcccaa
     9481 gtgacttatg atggaaaaat ctacggagaa cctgcagtaa tcgagaccct tgttttgtac
     9541 tataacaaag atttagtcga tacagcacca tcaacgttta aagatttgga gaatctatcc
     9601 aaagacagtc gttttgcttt tgagtcagaa gcaggaaaaa atacaggatt tttagctaaa
     9661 tggactgact tttattattc ctatggttta attgcaggtt acggtggcta tgtatttggt
     9721 gatgatggca caaatccttc agatatcggt ttgaataatg caggtgctgt agaaggaatc
     9781 tcttatgcaa cagattggtt caaaaatgtt tggccaaagg gaatgcaaga cataaaaagt
     9841 gcaggagact tcgccagcca gcaattcatg tccaataaaa ctgcagcaat cattgacggt
     9901 ccatggcaag cgcaaacata caaagaaaac aatatcaatt atggtgtagc caaaattcct
     9961 actctaaata atggacagcc ttatcaaccg tttggcggag gaaaaggatg ggtagtcagc
    10021 aattatgcta aaaacaaaga cctctctcaa aaatggcttg attatgtaac gaatcaggaa
    10081 aatcaagaaa aattctttga aatggtaaat gaaatccctg caaaccaaca agctagggaa
    10141 acagcaaagg ctaaaaacga tgaattaaca acagctgtga ttgaacaata tgaaacagct
    10201 caagcgatgc caaacatccc agaaatgggc gaagtttgga caggtgcaga aaacttgatg
    10261 ttcgatgcag catcaggttc aaaaacacca aaagaatccg cagatgaagc agtaaaaaca
    10321 atcagtgaag ccatagaaca aaaatactga ttaaaatgat aaccgtccat ttttataaaa
    10381 aatggaacag gtgcttcaga taaaagtggc aagagcgaga tggaaaatta tcttgctctt
    10441 gttgccatta tcttaaaagc agtttgcggt ttagcaagtt tagagggggc attcagatgc
    10501 agcaagataa aacaagcaat atcaacgaaa aaaaaatcac gctttgttca cttattccag
    10561 ggatggggca gtttgtaaat ggccaagctt ttaaaggtat cgtttttttc gccatattcg
    10621 tcctattcat tggtcagatg cttctgggcg gatttcatgc attggtagga ttggttactt
    10681 tgggaagtat accaatggaa gatcattcat tatttatttt gattgaaggc actttgcaat
    10741 tcatcattac aatcattttc ttgatttttt acggtttgaa tcttttagac gcttatcgag
    10801 tagcgaagat gcgtcaagag ggcaaaaaaa tcaatcggac gatgaaggaa gtcatacata
    10861 atataggtga tgaaggtttt ccttatctat tgacacttcc cgcttatctt ctcatgattt
    10921 ttacgatcat tttcccagtc ctagttacat tgttcactgc atttactaat tatgacttca
    10981 atcatattcc accagccagt ttaattgatt gggtaggggc taaaaacttt tttagtatct
    11041 tctttttaag ctcatatcgt aatacttttt ttgcagtctt ttcgtggacc gtgatttgga
    11101 ctttatgtgc aacaactttg caaatcaccc ttggtattct cacagcggtt gttgctcacc
    11161 agaaatttat taaattcaaa cgtattttcg gtatcatttt cttattacca tgggcggtcc
    11221 cagcttttat tactatcatg agtttttcga atatattcaa cgatagcgta ggtgccatca
    11281 atactcaagt gattcctttc ataaaccagc ttccttttgt agatatcagt gcaatctctt
    11341 ggaaaacgga cccgaactgg acgaaagtag caattatctt agtgcagggc tggttaggat
    11401 ttccctatat ctatgtgatg gttacaggaa tcttacaatc gatttcagaa gacttatatg
    11461 aagcagcaaa aatcgacgga gcaaatgcat ggcagcgctt ttcaaacatc acgcttcctg
    11521 ctgtcttcct agtggcagcg ccaacattta ttacacagta tacggggaat ttcaataatt
    11581 tctccatgat ctatctgttt aacaatggtg gtcccggaag cgtaggcgga ggagctggtt
    11641 ctactgatat tcttatttcc tggatctata aacttacgac tggaacttct ccgcagtatt
    11701 ctatggcttc agcaatcacg ttgattatct ccgtcatcgt tatctgtgtg tcattgctgg
    11761 tatttaaaaa gacaaatgcg ttcaatatgg gggattaaca atgaaaaaat ttcattcgag
    11821 tgctcgattc caaaaacgac tttctcactt ttttacttac ttttttcttt taatactgtc
    11881 agtcattatc atctatccgc ttttgatcac agcaagtact gccttcaagt caggaaatat
    11941 tgcagctttt agtttagatc tttcaagtga ctggacttta ggaaacttta ctcggctatt
    12001 cagtgaaaca ctttacggga cttggtataa aaatacattg atcatttctg tcctaacaat
    12061 gatcgtacaa gtgactgtag taactttggc gggctatact tatagtcgct atcgttttat
    12121 cggccgcaaa tcaagtttga tgttcttttt agtgattcag atggtaccga ctatggcagc
    12181 attgactgcc ttttatgtca tggctttctt attagaagcg ctcgataagt actggttctt
    12241 gacaatgatc tatataggcg gtggaattcc aatgaatact tggctgatga aaggatactt
    12301 tgacactgta ccaatagatt tagatgaatc tgctaaactt gatggggcag ggcatttcag
    12361 gatttttttc cagattgtat taccgcttgt caaaccgatg ctcgccgttc aagcattatg
    12421 ggcttttatg ggaccttttg gggatttcat gttagctaag ttcctgcttc gaacacctga
    12481 aaatcagact gttgctgtcg gcttacaaac atttatttct gatgtgacaa accaaagagt
    12541 ctctcttttt gctgctgggg caattttgat tgcactaccg atttgtctat tattcttctt
    12601 tttacaaaag aactttgtta ccggcctgac atctggcgga acaaaaggat aggagcagag
    12661 tatcatgcaa acatttccgt taaactattt ttccgcatta cgtacgccaa ctcaagtgtt
    12721 tgcgggacgc aaactattat catggcctaa atttttcttg atatttgtat ttttagtttc
    12781 cttgatggtc atgcctgtga ctctttttta tgccaatcag atccaagcga ttccattaga
    12841 acaatttcta tccgttcatt cgctgatcga tgaacaagga acccaaaaat tttctgaact
    12901 tgaattatct gaaactgggt tacaagcatc gcaacaaacg atagctgtga cccctgaaat
    12961 tttggtaggt gtgtctttat ctgagaaaca acaatccgat catggaactt ttattgattt
    13021 tgagaaggaa caatgggtga tccaacaaaa ggataaatct ggtatacgcc gctatacgat
    13081 gaattatagc ccatctttcc aaccagattc tgtacgtacg cccgaagatt tccaacgatt
    13141 tttagaaaga gaattttatg ccagtaatcg tccaacaatc attttatctt atagtttaag
    13201 tcttggtctt gtcctatttg tcatgacgag tctcatttta ttcggggctt cctttttctt
    13261 gtggatgaca agaaaaagcc aactttcatc cattcataca ttcaaagaga gtgcaaattt
    13321 gatgctgaat gttatgggaa taggttccat ggcagcagca gttgtagggt ttatccactt
    13381 tgactttatc ttgatgctaa gtgtccaaac aacgataact gtcttgctgc ttttatgggt
    13441 ttttgtcaaa acaagattca aagataagcg tgtcgaatga
//
LOCUS       DACGEU010000074        13145 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.074, whole genome shotgun sequence.
ACCESSION   DACGEU010000074 DACGEU010000000
VERSION     DACGEU010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13145)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13145)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13145
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.074"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(77..149)
                     /locus_tag="IXR40_002081"
     tRNA            complement(77..149)
                     /locus_tag="IXR40_002081"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(114..116),aa:Lys,seq:ctt)
     gene            530..1099
                     /locus_tag="IXR40_002082"
     CDS             530..1099
                     /locus_tag="IXR40_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HAQ4361913.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            1086..1946
                     /locus_tag="IXR40_002083"
     CDS             1086..1946
                     /locus_tag="IXR40_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAQ4361914.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITSEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            2136..2840
                     /locus_tag="IXR40_002084"
     CDS             2136..2840
                     /locus_tag="IXR40_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4361915.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            2845..4680
                     /gene="walK"
                     /locus_tag="IXR40_002085"
     CDS             2845..4680
                     /gene="walK"
                     /locus_tag="IXR40_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HAQ4361916.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVVLSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            4677..5993
                     /locus_tag="IXR40_002086"
     CDS             4677..5993
                     /locus_tag="IXR40_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361917.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            5994..6863
                     /locus_tag="IXR40_002087"
     CDS             5994..6863
                     /locus_tag="IXR40_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361918.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            6918..7727
                     /locus_tag="IXR40_002088"
     CDS             6918..7727
                     /locus_tag="IXR40_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAQ4361919.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(7830..8459)
                     /locus_tag="IXR40_002089"
     CDS             complement(7830..8459)
                     /locus_tag="IXR40_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HAQ4361920.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAAGDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            8629..9921
                     /locus_tag="IXR40_002090"
     CDS             8629..9921
                     /locus_tag="IXR40_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4361921.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQQLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            complement(9997..10659)
                     /locus_tag="IXR40_002091"
     CDS             complement(9997..10659)
                     /locus_tag="IXR40_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HAQ4361922.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            10884..11168
                     /locus_tag="IXR40_002092"
     CDS             10884..11168
                     /locus_tag="IXR40_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HAQ4361923.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            11219..12844
                     /gene="groL"
                     /locus_tag="IXR40_002093"
     CDS             11219..12844
                     /gene="groL"
                     /locus_tag="IXR40_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HAQ4361924.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDVTIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
BASE COUNT         4369 a         2264 c         2833 g         3679 t
ORIGIN      
        1 taaaaaaaga acagcgtaaa tgttttcgaa atgctttcgc accaacattt acctgttccg
       61 tgggtttggc acccaatggg ccgtgagggg ctcgaacccg cgacccgctg attaagagtc
      121 agctgctcta ccaactgagc taacggcccg tacaaaaagt acttaataat agtagcacta
      181 agaattttaa aatgcaagac tacatttaaa gaaaatcaga aaaatcttta cttccttata
      241 ggaaatcatt catagattat tcacatttgc tcgctattat ataagcatac caacaaacaa
      301 agttcttgca agagaacaaa ccctaacact tttttcattt tttactcctt tcccgccgtc
      361 tccccggcgg gtctcctgtt cttaacgata aaagacaaga aggcttagcc ttcttgtttt
      421 ttgttttcat ggaatcccgc taatcaaatc acctagttaa agcaactaga ttgaatgttt
      481 atcataagtc tgatatcatg tttatgaaat gaaaaaagga gcggttatga tggaaaaaat
      541 gcgtcagcaa ttaatggagt gggggaagga actagaaaca ttccgtctgc ctcactggga
      601 agaactccct gacttagaac tttatatgga ccaagtcaga acgttagttg atcgttatct
      661 ttcacctgtg atacaaggag aaaagcatcc attgcttacc tcttctatgg taaacaatta
      721 cgttaaacta ggtttgatac cagcaccagt taaaaaaaga tataacaaag aacacgtagc
      781 atttttactt gcaatcacta cgttgaaaca agtattgact attcctgaaa tcaaagaagg
      841 gatattgttc caaggaaaaa cagtaggaat tcgtgaagcc tataatctat tttgcgatga
      901 acaagaagca gctgtgtgga tggtcagcca attagcacaa ggtaaatctc atccgcaaaa
      961 attcgaccag gcaacccctg tagaatatat tgctgtaaga gcggcaactt tatcgtttgc
     1021 aatgaaactt cttgcggaaa aaacgattgt tctagaaacc gaatatttaa aagaggagaa
     1081 aacaaatgaa aaacaataaa atcgcaattt tagtagattc aggtacggat gtgccagaag
     1141 aattgataaa aaaatacgag atgtatatga tcccattgaa aattatttat aaagatcagg
     1201 tatatacaga taaaattgac attacctctg aagagatcta tcaacgtttg ccagaggaaa
     1261 tccctggtac atctttgccg gatggtgagt cgatcacaga aatctttgag caaatcaaaa
     1321 aagacggtta tgaaaaggta cttgcggtaa caatttccag tggattgagc gggacatata
     1381 atgtggttcg tttaattgca caacagcaag aagaattgga agcatatgta ctagatacga
     1441 aaaatattgg tattggtgca ggtttttctg cgatccaagc agcaaaatgg ctggaagaag
     1501 gagtagaatg ggatcaactg atcagtaatc tgaatgagtt agtcgaaaga acaaaagttt
     1561 tctttaatgt tgcgacattg gaatatcttc aaaaaggtgg acggatcggt ttagttgctt
     1621 ctattgtagg aaccgcttta aagcttaacc caatcatctc atgtaatgaa gaagggattt
     1681 attacacagt aggaaaagct aggggacgta aaaaaagttt ggataaaacg gttgcttacg
     1741 tcaaagaaaa aatcggtaat gcaaaggtct tcaacttagc tgttgcccat ggggatgcga
     1801 aagaagaagc aattgaaatg gaagcgagac ttaaaagaga gttcccacaa gcaaaccaaa
     1861 tctactttgg ccagatttct ccggcattag tagtccacac tggtccggga ttattgggtg
     1921 tcggtgtaca agttttagaa ggataaatca aaaaaaggaa acactgaggt gaaaatcagt
     1981 gttttccttt tttattgaag ttagaacaaa aaataataaa gtattttgca ctttcatttt
     2041 aattttctct tttgttttat aggcaaagat gaaacaaaag cagaaatacg gtataatgag
     2101 aaggtatgac aataatatat aagaggtggc tctttatgaa aaaagtttta gttgtcgatg
     2161 atgagaagcc gatttcggat atcgtcaaat tcaatttagc caaagaaggc tatgatgttt
     2221 atactgcata tgatggggaa gaagccttgg aaaaagttgc tgaggtagaa cctgatttga
     2281 ttttacttga tttgatgcta cctaaaatgg acggcttaga agttgctcgt gaggtacgca
     2341 aaacttatga tatgccgatc attatggtaa cagccaaaga ttctgaaatt gataaagtcc
     2401 taggcttaga gttaggcgcc gatgattacg tgaccaagcc attttccaac cgagaattag
     2461 ttgcacgtgt caaagcaaat cttcgtcgcg gtgccacggc tgcgaaggaa ccagaagagg
     2521 cagcacctgc ggaattgacg attggtgatt tgacgatcca tccagaagct tacatggtga
     2581 cgaaacgagg agaaacaatc gagttaacac atcgtgaatt cgaactactc ttttacttgg
     2641 cgaagcacct tggacaagtg atgacaagag aacatttatt acaaacggtt tggggttatg
     2701 attattttgg agatgtacga acagtggatg taactgtacg tcgtttgcgt gaaaagatcg
     2761 aagataatcc aagccatcca aattatttag tgacacgtcg tggtgtcggt tactatttgc
     2821 gtaacccaga acaggagtaa ttggatgaaa agaaaagtcc gcttttttcg atcagtcaat
     2881 tttaagatcg ctattacctt tattctgatt ttattgatct cgatcgaaat tattggtgcc
     2941 tactttatac gtggtttaga acgttccacg atcaatacat ttattaaaga tatgaatcaa
     3001 acggtggaat cattagcaac aacaatcagc ccggaattga atcgaaaaga taatgcagat
     3061 gatgaagagg taaatgcgaa tatcaaaaga tttattgaaa acagtgcgac tagcgatatc
     3121 atcgaaatac gggtcgttga cgaaaaaggg atcatccgag gaacaaccga tgtcaatgaa
     3181 caaagcgctg tgggaaagaa aaatgattat gttgatatca atgatttcac gactaaacgt
     3241 tatgttgctt tagataacga cgataaacgg gtgaatatca atgttcaacc gatcctgtcc
     3301 ccgaccggcg atgccgttat cggggctctt tacgtcaaaa gtaatatcga acaaaaatat
     3361 tcggaaatca ataacacagc agtcattttc tttactgcct cactaattgc ggcatttatt
     3421 tcaatgatcg tatctgtttt agttgctcgt tcgattacac agccgatcgg tgaaatgaga
     3481 gaacaagcca ttcgaatcgc tagaggagac tacagtcgga aagtcaaagt gcatggacaa
     3541 gatgaacttg gacagctggc tgataccttc aatcagttag ctgaacgtat tgaagaagct
     3601 caagatacaa tggaagctga acgcaatcgt ttggatagcg tgctatccca tatgacagac
     3661 ggcgtcattg cgacagatcg caggggtaaa gtcattacga tcaatgatat ggctgtttcc
     3721 ttgctagata tcaaaaacga ggaagcaatc ggacaatcga ttttgacact tttagatatc
     3781 gaagaagaat atacgttgcg gaaattatta gaagatccaa acgaaatggt acttgaccgt
     3841 tcaaccagta cattggaaag tgatcagatg atcttgcgag tagacttttc tatgatccgt
     3901 cgcgaatcag gttttatcag cggattagta gctgtcttgc atgatgtgac agaacaagaa
     3961 aaaacagaac gggaacgtcg tgaattcgtc tctaatgttt cccatgaact tcgtacaccg
     4021 ttgacaagta tgcgtagtta tatcgaagca ttgagcgaag gtgcgtggaa agacgaggaa
     4081 gtagcaccaa attttttgaa ggtaacgcta gatgaaacag accgaatgat tcgaatgatc
     4141 aatgacctct taaatctatc tcgcatggat acaggtaata cccagcttca attagaatat
     4201 gtcaatttca acgagttagt gaattttgtt cttgaccggt ttgatatgat ggtgggaaat
     4261 caggaaaaaa attataagat ccgtcgtgaa tttacgcaaa gagatctttg ggtcgaagta
     4321 gatacagata aaatcatcca agtagtcgat aatatcatga ataacgcgat caagtattca
     4381 ccagatgggg gaacgattac ttgtcgctta ttagaaacgc ataataacgt ggttttaagt
     4441 atcaccgatc aaggattggg gattcctaaa aaagatctga accgagtgtt cgagcggttc
     4501 tatcgagtag ataaagcacg tgcaagagca caaggtggga caggacttgg attagctatt
     4561 tctagagaag tgattaaggc gcatcgaggc gctatttggg cagagagcaa ggaaggaaaa
     4621 gggtcgactt tttatatctc gctgccatat gaaccttatg aggaggaatg gtgggaatga
     4681 gaatctctga aaaagtcgtt cgtataggac tcattttgat ggttgcgtta agcatatact
     4741 tctcttatgc aatctggctg agcccagcag gaaaaagttc aatcaacgta gatgagacaa
     4801 acactcaaat gatcgagtct caaagcaatc gaaaaacttc cgaagtcttt cttccgcttc
     4861 atgttacatg gcaccattcg ggaatgatcc aagaaaccaa cagtgaaaat ctcgtgtacc
     4921 gattgcaatt gatcatcgat aaagcaagat ttggaaagct ttctgaagta gtttcaggag
     4981 acaaatcaca gtttgaacag gtgaaaaatc tgaactctgg ttttgagttg gcctataatg
     5041 cgcctttttt gctaagagaa tacaaggaag catttgattt agatttagat gtgtcgaact
     5101 tggcaaaaga aagcgaaaat atgtatttta ctagaataca attcgatcaa ggaaataaaa
     5161 aaatccgatt tttgaattat tcgaaccatc tcgtatatga agcaaatatt tcgttgaatt
     5221 ggacagatat caataaagaa ttaacagcaa aagacacaaa atggacagaa atgacaacag
     5281 aaccatcgac gatcgacacg caatatgcta cgaaacattc gatcaaactg aaaaagtata
     5341 gttatatcct gtcacagcaa ccctatacac tttttagaaa tgcttttttc cagaaaccag
     5401 atagcgtgaa aaataatgat gaaagcaatg aattgatttt ttacggtggg aatgaaacaa
     5461 tgtctatcca ttcggaaacg caagtagttg attttcgtgg agagctgcca gagaaaaaag
     5521 aaaatgctag tgtattttct gaaagtttcc cctatattag caaattaggc agttctttag
     5581 ggaacctcag atattttgac cgcagtgaca atacgatcga ttatcggata ttcgtggaag
     5641 gcttcccggt ttttgggaca gacagcagag gacagattgg tgtggaagtt ggcggtgaaa
     5701 cgaatggttc tgtgcaagtg aatatccaaa ccagtttgaa tacgattcaa gtgccgatac
     5761 cttcagacga agaagtagaa cttgcaagta cgaatgaaat catccagcag ttaaaagcta
     5821 agggagcaga tagcaacaag attggttcag tgatcgttgg ctatacatgg caaaatgtca
     5881 aagaaacgaa tcgtgtcgtt gatctcttac ctgaatggta tgtgaaatat aaagataact
     5941 ggtattcagc taacgacctt ctggaaaaat tacctggatt ggaggcgaat taattggatt
     6001 tcaaaaaaat cgaatggata tttttcgtcg cttttttagg gttgaatgtg tttttattca
     6061 gcagttatca tgacgcggta taccaagaaa acaatgtcat tcgctctaat cagactgaat
     6121 caatccaaca acgtctggct agcgacgata tcacttacac ggggaagatt tcgtctgaga
     6181 acaagcaagg ctattatctt agcgcggagc agaccaatct tagcacttca ttagcgaatt
     6241 atcgcaaggc tggtaaaagc ggcttgctgg caagtggtgt gtttttagac ggtgatgttt
     6301 tgacgaaatc tttatccagt tcagatgctg aaaagaacgt gatcgatcca gataaaatta
     6361 gtagttcctt ggaagatttt ttatctaaca aagacaatat tttattcggt aatgattatg
     6421 tgtacacgaa aaacttttct catttagaag aagaaccact agaaatccaa gcaagccaag
     6481 agtatgaagg catcccattc aatgatgata cagcaaaaat cgttctttct ttagaaaaaa
     6541 acgataatga ttatagcatc acgaaataca tgcagacgca tttatctgat atcgagcagc
     6601 tgcgcgaaaa gacggaactg tatacggaag aggaagcaat caatacattg tacatcaata
     6661 acaaaatacc aagaggatca aaaattttat ggcgtcagct agcttattcc tgtattctga
     6721 aagtccggga aaaaaatgtg tatgttcctg tttggcatgt agcgatcgaa acaagcgata
     6781 aagtggtcca aattgagagt gtcaacgctt tcagcaatac gatcgtgaca aacaatactg
     6841 taccaaaagt ggaagatcaa taaaaaagcg agtataatga aaaaagttta caaagtaaga
     6901 agggaagtag gagtcaaatg gctgaagaaa aaccagcttt taaaatcagt atcctagcaa
     6961 gtggaagttc gggtaattca ctttatatcg aaagtgaaaa aaaacggctt ttggtcgatg
     7021 caggacttag cggtaaaaaa atcacttcct tgatggctca aattgatcgg acaccggacc
     7081 aattagatgg aatacttgtg acgcatgaac atcgagatca tatacatggc gtgggtgtct
     7141 tggctcgtaa gtatcatttg gatgtttttg ccaatcagca gacttgggaa gcgatggaac
     7201 cactgattgg aaatgtacca gtggaacaaa aacatctatt tgagatgggg aaagtcagaa
     7261 cattcggcga tatcgatatt gagagtttcg gcgtctccca tgacgcagcg gctccgcaat
     7321 tttatcgttt ccataaagaa aatcggtcat tcgtcatgtt gacggacacc ggatattgca
     7381 gtgattatat gcgaggtgtc attgaaaatg ccgatggtta tttgatggaa agtaatcatg
     7441 atcttgagat gttacgcatg ggaccttatc cgtggaattt aaaacagcgt attttaggag
     7501 atagaggaca tctttccaac gaagacggtg cacttgtcat gactgatgtg atcggtaatc
     7561 ggaccaaacg aatctatctt ggccatctta gcaaggaaaa caatatgaaa gaacttgctc
     7621 atttaacaat ggaaaatgtt ttgaaagaaa aagattttgg cgttggacat gattttgaaa
     7681 tctatgatac agatccagat gaagcaactg agctattttc gatttaaaca gttcaatcaa
     7741 taaaaatata aaaagcagaa gataaaatca atcagggttg gttttatctt ctatttttat
     7801 ttttttagca tattaaaaaa ataaccgtat tatcgactga ctacactgat gtgctgcttt
     7861 tcatgtttct catccagtat ctcatctact aatgcaatcg cgtaatctgc catgctgatc
     7921 gtactgtcgc cagcagcgtt tctttgtaaa taatcatcac ttaacaaata agtacctgta
     7981 cgtttgccat gtggatcaaa taaagaagct ggactgatat aagtccaatg tagattttta
     8041 gattgtttca attttaacaa tccttcgtac atattgaaag ctgttggata gaagggtgca
     8101 tttttaggta cttggtcaat catacgagtc gtcttttctg tatctaagaa taacgaagag
     8161 gcacccccaa cgacaattaa gcgtgtatcg gttccttcaa gcatctcaat caaatgggac
     8221 aaagaagttt gatgcatttc ttcttttcct ttgggagcgt tgaaagcatc aacgacaaca
     8281 tcaaaagatg caagatcagt agttgtcaac tcaaataaat ccttttgtat aaacggaaca
     8341 tctgatggca atttttctgg atgacgcacg attgccgtca cgtctaaatc tctggacaat
     8401 gcttcgtcta aaataaatga acctgcatgg ccagtagctc caatgagtgc aattttcata
     8461 aaaaacctcc ttttttattc ctgtccattg taagcagttg ctgaatattc gtcaaagaat
     8521 ccgatttttg aaaagctcag tgcgcattcc tttcatggtt cgtgatcatt gggtatagtt
     8581 aaattaagaa aactgattga taaaaataga agttgaagga gataagaaat gaaagagtgg
     8641 ttagatcgtg cctttttacc aatgataaca tctgttgtga atcttagacc cttaactgct
     8701 ttgcgtaatg gaatgactta cacgatccca ataattattg ttggctcgct gtttttctta
     8761 tttgctcatt ttcctgtgga ttacatcgct cagtggatag acaaaacagg attttctatg
     8821 tattttacac aagtatacca ggctacattt gatgtgatag ccttttggat cgtttttgcc
     8881 attgcatacg cttatgcaaa agaagaagac atcgatcgct taccagtcgg cataacagcc
     8941 ttgtctgctt atctactgct tattcagcca ctaaatactc agatagatac tgtctggaca
     9001 ggtgctgaag ggatactagg agcagttaca actgggctca tcatcggatg gggctatgca
     9061 cgtttagtaa gacttgcgaa agggtggaag caaagagaga agatacctga aaatgtttgg
     9121 cagtctttta cttcattgat tccaatcatt gttatagtca cttttacgct tatcggttca
     9181 gcggtttttc aacagttgtt cagaatgact gttgttcaag gagtatggac atatgtccag
     9241 cttcccattc aatcgttcat agacacgttg tttggtgtgc ttttattagg tttttttgtt
     9301 ccgtttttat ggttatttgg tcttcatgga tctgcgatgg tcaatgggtt ggttagtccc
     9361 gtcttgcaag cgaattcatt agcgaatgca gaaatcttag cctcaggaca agagttgacg
     9421 gtggcaaatg gcggacatat cgttactcag caatttctcg atcagttcat gacggttacg
     9481 ggtgctggat tgacgttagg ggctgtattt tttatgacgg tttttgcgaa atcgaagaaa
     9541 tacagagaat taggaaatct tgctctttta ccagcctttt tcaacatcaa tgaatcaatt
     9601 attttttcca caccgatcgt gatgaacccg atgatggctg ttccttttat tttcgcaccg
     9661 gtcgtttcag gattgattac ctattccgct ttatattttg gattcgttcc tttatttaca
     9721 gcagtccaag tcccttggac aacaccgccg atcctctcgg gtttcttagt aggcggagtg
     9781 cctgcagcga ttttacaagg tatcgtgttg tcaattagtt ttttcattta tttcccattt
     9841 ttgaaaaaaa tagattctgc aaactgcaaa aaggaaagac agacaaaaaa tgatggagca
     9901 gcagaaaaga tgaacgacta aaaaacaaaa atactcctgt cgctttagat tgggaaaatc
     9961 accaatctag gatgacagga gtatttatag tcatgtttat actagccctt tttggacagc
    10021 taattgaaca agaacaacta atgtgttcat tcctacgtgt gtgatcatcg atgtccagat
    10081 ccgaccagtt gctttgtact ctaggctgaa gaagaaacct aggaaaaagt agattagcag
    10141 atgaccatca ttatgagcaa acgcaaacag caaagagctg atcactgctc cgacccaaaa
    10201 atttgaatat cgactgatga tccccagtat actgcggcgg aatacgaact cttccatgat
    10261 gggtccagca acagttgtcg ccaaaataaa agcgggtgct tccatgatca tctggatgat
    10321 attttgtgta ttctcggaag gggttgcttt gccaaacaat acagattcta acatgacagc
    10381 gatgctttgc agaatcaatg cgacaaagat tccaaccaat ccataaataa caatctttgg
    10441 agcagaagct ttttttaccg ctgattcgat cgctaagggt tcacgttgct taaaataaaa
    10501 aatagctagg acaacggcgc ctagtatata catgactgca gttgctgtga tcaattcaga
    10561 cgtagatttt acaagtccta tcgaagctag gatcaagggt gagataaaaa ttagaccata
    10621 gcaaaaaatg ctgaggaagc tatatttttt taaagacatg taattcctcc ttttaaggga
    10681 taacaagcat gcaaggcaag cttatatcga ttgatttcaa ttatatcata atttcaataa
    10741 gcagctgtca gaataaaatt tcttttcttt gatttaaaag cttgcaaaaa agagggagaa
    10801 tgagtattat taaaaatgta ggttagcact cgaaggttaa gagtgctaac agattaaaaa
    10861 aagagttatc ggagggattt atcgtgttaa aaccattagg tgatcgcgtc attatcgaag
    10921 tcgcaaaaga agaagaaaaa actgtcggag gaatcgtttt agcttctgct gctaaagaga
    10981 aaccccaaac tgggacagtt gttgcagtcg gtgaaggccg tttgttagaa aacggtgaaa
    11041 aagttcctgc cgctgtaaaa gcaggcgacc aagttatgtt cgaaaaatac gccggtacag
    11101 aagtaaaata cgaaggaaaa gaatatctga tcgtcgcagg aaaagatatc atggcgattg
    11161 ttgagtaaat ttggaagata aaaaaataat caaaaataat caatgaggtg aatcaatcat
    11221 ggcaaaagaa ttgaaatttg cagaagacgc acgcgcagct atgttacgcg gggtagataa
    11281 attagcagat acagtgaaag taacattagg acctaaaggc cgaaatgtcg tactagaaaa
    11341 atcttacggc tctccattga tcacaaatga tggtgtgacg atcgcaaaag aaatcgaatt
    11401 agaagatcat tttgaaaaca tgggtgcaaa acttgtatca gaagtagcat caaaaacaaa
    11461 tgatattgca ggagacggta caacgacagc aactgttctg acacaagcaa tcgttcgcga
    11521 aggtttaaaa aacgtaactg caggtgctaa tcctctaggc attcgtcgcg ggatcgaatt
    11581 ggcaacaaaa gcagcagtcg aagaattgca taatatctca actgttgttg attcaaaaga
    11641 agccattgca caagtagcag ctgtttcttc gggttctgat aaagttggac atttgattgc
    11701 tgatgcaatg gaaaaagttg gaaacgacgg tgtcatcaca atcgaagaat caaaagggat
    11761 cgaaacagaa ctagatgttg tagaaggtat gcagtttgat cgtggttact tatcacaata
    11821 tatggtaaca gataacgaca aaatggaagc tgttctagaa aacccatata tcttgatcac
    11881 agacaaaaaa atctctaaca tccaagatat tctgccattg ttagaacaaa tcttgcaaca
    11941 atcacgtcca ttgttgatta ttgctgacga tgtagatggt gaagcattgc caactcttgt
    12001 attgaacaaa atccgtggaa cattcaacgt agtagctgta aaagctcctg gtttcggcga
    12061 tcgtcgtaaa gcaatgcttg aagatatcgc tattttgaca ggtggtacag taattactga
    12121 cgatctaggt ttagaattga aagatgtaac aatcgaaaac ttaggaaatg cttctaaagt
    12181 tgttgtagat aaagacaata caacgatcgt agaaggttct ggagaaaaag aagcaatcga
    12241 agctcgtgtg caattgatca aaaaccaaat tgctgaaaca acttctgatt ttgaccgcga
    12301 aaaattacaa gaacgcttag ctaaattagc aggtggtgta gctgttgtta aagttggtgc
    12361 agctactgaa acagaattga aagaattaaa attacgcatt gaagatgcat tgaatgctac
    12421 acgtgccgca gtagaagaag gaatggtctc aggtggtggt acagctctag tgaacgttat
    12481 cagcaaagtt tctgctgtag aagcagaagg agacgtggca acaggtatca agatcgttgt
    12541 tcgtgcttta gaagaaccaa ttcgtcaaat cgctgaaaac gctggttatg aaggatcagt
    12601 gattgttgat aaattgaaga acgtggaact aggcactggt ttcaatgctg ctactggaga
    12661 atgggtaaac atggttgaag caggtatcgt agacccaact aaagtaacac gttctgcctt
    12721 gcaaaatgcc gcttccgttt ctgccttgtt attaacgaca gaagcagtcg ttgcagataa
    12781 accagaacca gcagcgccag cagctcctgc aatggatcca tcaatgatgg gcggtatgat
    12841 gtaagaaaaa gcaacttgct tatctacaac tgatcattag tgaaagacag ataaaaagag
    12901 gctggaacag aagcgtttaa ctccaagaaa taagaagaaa ttcacggaaa ttgcttttca
    12961 aatttttgtg aatttcagct tatttccgaa ggagttgctt ctgcttccgc tgtttatacg
    13021 tgtttagagc gtgagacaaa agtgttcttt acttttgtcc cacgctcttt tttgtgtgta
    13081 attataatga aaatagttat ttttaatagt tataatattt tatctattaa aagtaaatat
    13141 ccatt
//
LOCUS       DACGEU010000075        12935 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.075, whole genome shotgun sequence.
ACCESSION   DACGEU010000075 DACGEU010000000
VERSION     DACGEU010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12935)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12935)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12935
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.075"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            451..1581
                     /locus_tag="IXR40_002094"
     CDS             451..1581
                     /locus_tag="IXR40_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HAQ4361925.1"
                     /translation="MGPYLTLSMIGLLEVYSASSYRLLQADENTKSLLLRQLIFIFLS
                     WSVIFLARSVKLHYLLHPKIAGYGLALSIFFLVLVRIGIFGVTVNGAQRWISLFGIQF
                     QPSELANLFLIFYLSWFFRDGNSSPKDLKKPFLITVGITFLILFQPKIAGALMILSIA
                     WVIFWAAAVPFKKGIYLIVTFSALLIGAAGGVLYLGNKGWLPQMFNHAYERIATLRDS
                     FIDSHGAGYQMTHSFYALYNGGIFGRGLGNSITKKGYLPETETDFIFSIITEELGLIG
                     ALCVLFLLFSLCMRIFCLSSRCKNQQAGLFLLGFGTLLFVQTIMNVGSIAGLMPMTGV
                     PLPFVSYGGTSYLILSLGIGITLNISSKIQAEELALYRPEKQ"
     gene            1673..2428
                     /locus_tag="IXR40_002095"
     CDS             1673..2428
                     /locus_tag="IXR40_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HAQ4361926.1"
                     /translation="MKVSQKIILSILLLLTLVVGYFSIEFIHGFSSAKQSSTVKKVEP
                     KSIPTTLNVALIGSDARSKDENGRSDSLLVAQYNQKTQQAKLISIMRDSYVDIPGYGM
                     NKINAAYSYGGVDLLNQTLKENFKFEAPYYASITFQDFIDCVNELFPGGVKIDAEKSL
                     DLDGVYINKGEQVMDGNTLLQYARFREDKEGDFGRIRRQQQVIKAISQQLKDVTSIFK
                     LPKAVGKLLGSIQTNLPESVLLDCGMDFLKDIC"
     gene            2486..4525
                     /locus_tag="IXR40_002096"
     CDS             2486..4525
                     /locus_tag="IXR40_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HAQ4361927.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKTAFDSLGGKAGSTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKMITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSYQATRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLITPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(4634..5785)
                     /locus_tag="IXR40_002097"
     CDS             complement(4634..5785)
                     /locus_tag="IXR40_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HAQ4361928.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYIADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(5939..6469)
                     /locus_tag="IXR40_002098"
     CDS             complement(5939..6469)
                     /locus_tag="IXR40_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361929.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(6568..6918)
                     /locus_tag="IXR40_002099"
     CDS             complement(6568..6918)
                     /locus_tag="IXR40_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HAQ4361930.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            complement(7075..8604)
                     /gene="ahpF"
                     /locus_tag="IXR40_002100"
     CDS             complement(7075..8604)
                     /gene="ahpF"
                     /locus_tag="IXR40_002100"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HAQ4361931.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     GTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(8614..9177)
                     /gene="ahpC"
                     /locus_tag="IXR40_002101"
     CDS             complement(8614..9177)
                     /gene="ahpC"
                     /locus_tag="IXR40_002101"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003756453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HAQ4361932.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(9321..9983)
                     /locus_tag="IXR40_002102"
     CDS             complement(9321..9983)
                     /locus_tag="IXR40_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAQ4361933.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            10167..11813
                     /locus_tag="IXR40_002103"
     CDS             10167..11813
                     /locus_tag="IXR40_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HAQ4361934.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAALLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPDMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDFQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            11804..12886
                     /gene="uxuA"
                     /locus_tag="IXR40_002104"
     CDS             11804..12886
                     /gene="uxuA"
                     /locus_tag="IXR40_002104"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HAQ4361935.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFELPGWEP
                     ERLAHIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLP
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNGYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
BASE COUNT         4267 a         2386 c         2473 g         3809 t
ORIGIN      
        1 aacgggattc tttcaactta tttgttattt ttttctaaaa aatattaaag attgttaaat
       61 ttcactattt catttcaaat tccattgcct aatcattagg aaaagtctat catgaactcg
      121 taaatagaat atagtaataa ccttgttagg tgaggctcct atacaaacat aggctgttgc
      181 ccagaaacgt cgaaagtcgc caatgggtaa aacagaaact gttggattaa ggctttttcc
      241 aatagctaag aatgttttct ttacgttgta tagtgctaaa actcggacga tgagatgatg
      301 ctaggtcaga attcttgttc gaaaaggttt ctgacctttt ctttatattt ttgtgactga
      361 cttatttgat gagacaaact cgctcctcac ctgacaagtg gattgctgtg tgaggaggag
      421 atgcggtgaa aaaagatcga ttggtggatt ttgggtcctt atttgacttt gtccatgatc
      481 ggtcttttag aagtatacag tgccagttct tatcgtttat tgcaagccga tgaaaataca
      541 aaaagtctat tattgcgtca actaattttc atatttttga gttggagcgt gatcttctta
      601 gctcgttcag tcaaactaca ctatttactt caccctaaaa tagcaggata cggtttagcc
      661 ttatcgattt tctttttagt attagtaaga atagggatat tcggtgtcac tgtcaacggc
      721 gcacaacgtt ggatctctct gtttggcatt caattccagc cttctgaact ggcaaatctt
      781 tttttgattt tttatttaag ctggtttttt cgtgacggaa atagtagccc aaaagatcta
      841 aaaaaaccat tcctgattac agtaggtata acttttctga ttttatttca gccaaagatt
      901 gctggagcat tgatgatcct ttcgattgcg tgggtcatat tttgggcagc ggcggttcca
      961 tttaaaaaag ggatctatct aatcgttact ttttctgcat tgctgattgg agcagcaggc
     1021 ggggtattat atttaggaaa taaaggttgg cttccacaga tgtttaatca tgcttatgaa
     1081 aggatcgcga ctttaagaga ttcttttatc gatagtcatg gtgcgggcta tcaaatgacc
     1141 cattcgtttt atgcactata taatggtggc atatttgggc ggggattagg aaatagtatc
     1201 acaaaaaaag ggtatcttcc agagacagaa acagatttta ttttttcgat tattacagaa
     1261 gagcttgggc taatcggtgc attgtgtgtg cttttcttat tgttctcatt atgcatgaga
     1321 atcttttgtt taagcagtcg ctgtaaaaat cagcaagctg gattgtttct tttaggattc
     1381 ggaactttgc tattcgttca gacgataatg aacgtgggaa gtatcgcggg gctgatgcca
     1441 atgactggtg tgccattgcc atttgttagc tacggaggaa caagttatct gatcctttct
     1501 ttaggaatcg gaatcacgtt gaatatttct tcaaagatac aggccgaaga gttggcgctc
     1561 tatcgacctg aaaaacaata aagagaaact gagaaactct cagtttgaat tatcataaag
     1621 tacaatcttt tatttttcaa gcgagaggtt cttttagaaa gaggaattcg caatgaaagt
     1681 atctcaaaaa atcatattat ctattttgtt actgcttaca ttagtagttg gctatttttc
     1741 gattgagttt atccatggat tttcgtctgc aaaacagagt tcaactgtga aaaaggtaga
     1801 gccgaaaagt atccctacca cactaaatgt ggctttgatt ggttcagatg ctcgttcgaa
     1861 agacgaaaac ggtcgctcgg attcacttct ggttgcacaa tacaaccaga aaacacaaca
     1921 agcaaaactg atctctatca tgagagattc atatgtcgat attccaggtt acggaatgaa
     1981 taagataaat gcagcttact cttatggggg agttgattta ttaaatcaaa cattaaagga
     2041 aaatttcaaa tttgaagctc cctattatgc aagtatcaca tttcaagatt ttatcgattg
     2101 cgttaatgaa ctgtttcctg gtggagtcaa gatcgatgca gaaaaatctc tagatttaga
     2161 tggcgtatat ataaacaaag gagagcaagt gatggatggt aatactttac tccagtatgc
     2221 tcgatttcgg gaagacaaag aaggagactt cgggaggatc agaaggcagc agcaagtgat
     2281 caaagctatc tctcagcagc tgaaagacgt aacttcaata ttcaagctac ccaaagcggt
     2341 tgggaaatta cttggtagta tccaaacgaa ccttccagaa agtgtgcttc tggattgtgg
     2401 tatggatttc ctcaaagaca tatgttagaa taaacaggta taaatagtga aataaaggaa
     2461 tgacaagcaa gagaaggagg aaaaaatgaa aagaagtgac aagcacggca aaaatcgaac
     2521 aggcgcttat attgccggcg cagtgatctt aatagcagct gcgggtggcg gttattttta
     2581 ctaccagcac tatcaagaaa cccaagcagt agaagctgga gaaaagacag ttgagcaatt
     2641 tgtccaagct ttgaacaagg gagattataa caaagctgca gaaatgacat caaaaaaggc
     2701 ggcaaataaa agtgcattat ctgaaaaaga gatcttagat aaataccaga atatatacgg
     2761 tgctgctgat gtcaaaggac ttcagatatc gaatctaaaa gtagataaaa aagacgattc
     2821 tacttacagt ttttcatata aagcaaagat gaatacctca ttaggtgaat tgaaagatct
     2881 ttcttataaa ggaacattag acagaaatga tggtcaaacc acgatcaact ggcaacccaa
     2941 cttggttttt ccagaaatgg aaggaaatga caaagtaagc ctgaccacac aagaagcagc
     3001 aagagggaat attatagatc gaaatggtga accattagca acaacaggca aactaaaaca
     3061 attaggagtc gttccaagta aacttggaga tggaggcgaa aaaacagcca atatcaaagc
     3121 gattgcttcc tccttcgact taacagaaga tgctatcaat caggcgattt cacaaagctg
     3181 ggtacaaccc gattactttg tcccattgaa aatcattgat ggagcaacgc cagaacttcc
     3241 agctggagct accattcaag aagtagacgg cagatattat cctttgggtg aagcagctgc
     3301 tcagctgatt ggttacgtgg gagatatcac agcagaagat attgataaga atccagaatt
     3361 aagcagtaat ggaaaaatcg gtcgctcagg tttggagatg gcttttgata aggatcttcg
     3421 tgggacaaca ggtgggaaat taagcattac agatgcagac ggtgtagaga aaaaagttct
     3481 gatcgaacat gaagttcaaa atggcaaaga tatcaaattg acaatcgatg cgaaggcaca
     3541 aaaaacagct tttgacagtc taggaggaaa agctggatca actgttgcga caacgccaaa
     3601 aaccggtgat cttcttgcgc ttgctagctc tccaagctat gatccaaaca aaatgacaaa
     3661 cgggatctca caagaagatt acaaagctta tgaagaaaat cctgaacatc cattcatcag
     3721 ccgatttgcg acaggttatg ctcctggatc tacgtttaaa atgattacag cagcaatcgg
     3781 tctcgacaac ggcactatcg atccaaatga agtgttgacg atcaacgggc ttaaatggca
     3841 aaaagacagt tcttggggat cttatcaagc aacgcgtgtc agtagtgatg tatcacaagt
     3901 agacttaaaa actgctttga tctattccga taatatatat gcggcacaag aaacgttgaa
     3961 aatgggtgag aaaaaatttc gtacaggctt agataaattc atttttggtg aagaccttga
     4021 tttgccaatt agtatgaatc cagcacaaat ttctaatgaa gatagcttta actcagatat
     4081 cttgctagct gatactggat atggacaggg cgaacttcta attactccta tccagcaagc
     4141 agcaatgtat tctgttttta ccaacaatgg cacacttgtc tatcctaaat tgattgcaga
     4201 taaagagaca aaagataaga agaatgtcat cagcgaaaca gcagtacaaa cgatcgtgcc
     4261 agatctgaga gaagttgtgc aagatgtaaa tggtacagca cattctcttt ctgctttagg
     4321 gattccgttg gcagcgaaaa ctggtacagc ggaaatcaaa gaaaaacagg atgtaaaggg
     4381 gcaagagaac agtttcttgt ttgctttcaa tcttgataac caaggttata tgatggtcag
     4441 catgttggaa aataaagaag atgatgattc agcaaccaaa cgagcatcgg aactattgca
     4501 atacctcaac caaaattatc aataaaaaat tgctttttaa gtacagtaaa aggactgtgg
     4561 cgttatcgtc acagtccttt tttcaaataa acggttttca cgatgtctct ttcacaactt
     4621 ctttttgatt tactcacact tcataaactt tttttgtaaa atatttgaga acaagtggag
     4681 aaataagtgt acttaataaa atcacgataa ctaaaggtga atagtactgt ggttcgatca
     4741 attgactttg ctgtccaatt tgtaaaatga tcaaagccat ttctccacgc gaaatcatac
     4801 cagcaccgac catcaatgaa ctatgttgag aaaaaccggc aatctgagca ccaaaataac
     4861 ctccaagcaa tttggtcaaa atcgctacaa gcgtcaatat agaaataaag agtagttgtt
     4921 cactaaagtc agaaaaatca acttctaatc ctacactgac aaaaaatact ggtataaata
     4981 ctgcatatcc taaagcctct acattgtggt atacttcttc tttaaccttt gtctgactga
     5041 cagctatccc agcaaaaaaa gcaccaatga cagagctaag cccaacaaga tccgctatgt
     5101 aagacattcc taaacaaata actagcgata cgatgataat agaagaattt gcgtacactt
     5161 tttctgcaaa tgaaagtagg aaaggcgcaa tccatttgac taataagaaa ataaaaacaa
     5221 aataaattag ctgttcaatc aaaacaagcg gtaaagaagc attgctagaa gcttcccccg
     5281 ttagaaaaga taggctgaaa cttagaacta aaacgactaa aatgtcatct accacagaag
     5341 cacccaaaat tgttgatcct tcttttgtat tcactacgtt tagttctttt aatacttcta
     5401 ctgaaatact gacagaagtt gccgcaagaa taatcccaaa gaaaatcgct tcatttcccg
     5461 aaacttggaa tgctttgcct gtcaaccagc caaaaacaac cgggaagatg atcccaagca
     5521 aagcaacgaa cataccaggt cggaaatatt ttttcaaaag agataaatca ctttccagac
     5581 cagctaaaaa cattaataag atcacaccaa tctccgaaaa gtcatggact agaatatcag
     5641 gtttgaccca attcaatcca gcttggccta gcaaaacacc aacaagtaat tgtccaatca
     5701 ctgctgggat acctaatctc cgcgagatat gtgagccaat cgttgttgaa atcaatatca
     5761 ggcataaaat accaataaat tccattctca tcattccttt gtataaaata tagcccgaac
     5821 ttagcataac atacattatt gaaaaaatag gaaaatatac tcacaaaaaa accaacaatc
     5881 caaaagattt ttttggattg ttggttttta tacggtctat tttaataact aaaaatgatt
     5941 aacgtatagt catttttctt attctgatga aattgataat ctcctggatg cccatgaaaa
     6001 tcaaaataaa gccgaatatt tggaatagaa gcatcaaact tttgaatgga ttgaacaata
     6061 agacgaatcc gccaatcaac aacagaatac tactataaac actccaactt ttagcttttg
     6121 tattcatgct gaagaacaac tggaacaagc tgttgatgat aacagctaat ccaagaagaa
     6181 tcggcaggat agaaacgatt gcaggtgcaa aagcatagac gatcagagct aagatcagga
     6241 aaaaaagacc actgaacaga ccgatactcc aagaacctgt tttcctttta aaacggtaag
     6301 cctcaaaaag attcaacaac ccaagcaaaa caagataggc ggtgatcaga taaccgataa
     6361 aatgaaaaac agcagaaggg tttagcacaa tcgcaatccc agaaataata taaacagcag
     6421 ctcttaataa ggcgtatttt tgaatatttt gtttaatcgt ctcaaacata taagaaaacc
     6481 tcctttgact tattttaacg tgaactagtc attttaccaa attaaatgtt acagaatgag
     6541 cgaaggagaa gaatatctct ggaaaaatca acttctgagg atcttttcca tttttttgcc
     6601 ttttgctagc tcatcgatca ttttatctaa ataacgaatt tctttcatca agttatcctc
     6661 gatgtcttct actcgtacac cacaaacaac acctgtaatc aaggaacgtg aaggattggg
     6721 gacaggggct tccgcaaaaa attgttcgaa agtcacttgt ttttgtagtt gatattctag
     6781 ttctgtttgg gaataacccg tcagccaaca aatgatttca tctacttcct cttttatacg
     6841 atcttttctc tccgcttttg ctacatacat aggataaacg cttgcaaaac ttgtcgtaaa
     6901 aatacgattt tgcgccataa tcagtcacct ttcttttttt caaattattt actacttata
     6961 gtatataaga aaaagagaag aaaaagcgat tattcaaaaa aacaaaaagg attgtgacaa
     7021 aattcttgtc accatccttt tttccgctct ctgacttttt acaatcttca tagctcaagt
     7081 gcgcatcaga taatcgaatg ctcctaaagc tgcagtagct cctgaaccca ttgaaacaat
     7141 gatttgtttg tatggactat ctgtacaatc accagctgcg aaaacgccgg ggatattcgt
     7201 tgcgccattt ttctcggtca ctatttcatt tcttggattc atttcgatcg ttccatctag
     7261 ccaatccgta ttagggagta agccgactag aatgaatact cctgaaacag ctagtgtatg
     7321 catctccatc gtacggcgat cgatatagga gagagattct acctgattcg taccgctgat
     7381 ttctttcgtc gctgcatgtt tgataacagt gacattcgca agagagacta gtttatcctg
     7441 taagatttga tctgctttta attctggtaa gaattctaga acatatacat gttttgctaa
     7501 cccagccaaa tcgattgctg cttcaacacc agaattacca ccaccgataa cagcaatctc
     7561 ttttccttta aataaagggc cgtcacagtg tgggcaataa gcaattcctt tatttttaaa
     7621 ctctttttcg cctggtacat tgatagaacg ccagtgcgca cctgtcgcga tgatggcggt
     7681 ttttgcttta agtgatatac cgttagctaa gccaatatta ataaaatgtt gctctttatt
     7741 taaggaaacg gcctgttgat tcatcataat gtcgataggg taactacgca catgactttc
     7801 tacttgctgc atcaattttg gaccttctgt gtaagaggta ccaatcatat tttcaatccc
     7861 tagtgtttca acgacttgtc cgccgaaaga atcagcgaca agtcctgtac ggattccttt
     7921 acgtgctgca tagatagctg cactactagc tgctggtcca ccgccaatca ctaatacatc
     7981 ataaggttct ttttcaaaca actcttcttc aatcaaaggg ccagtgattt tttcaacaat
     8041 ttgttcgatc gtcatgcgtc cgctactaaa ttcttctcca tttaaaaaca cagttggcac
     8101 tgccatgatt tttttatcat cgatttcttt ttggaacatc ccaccttcaa tcatcgtatg
     8161 agtaatattt ggatttaata cagctaatat attcaatgcc tgtacaacgt cggggcaatt
     8221 atgacaagtc aagctaacat aactgtcaaa atgcaatgtt tgtgttattt ttttgatttt
     8281 aagactcaaa gattcactga ttttcggtgc ccgtccacta atttgtaaca tagccagtaa
     8341 aaaagaggaa aattcatgac cgagggggat accagcaaaa acgattccac tttctttgcc
     8401 aactggattg atagaaaaac taggtgtgcg catcgaatct cttttttccc aagagatttt
     8461 aggagacatt tctgctattt ccttcgtaaa ttcagctagt ttttgactat tttcactatt
     8521 atccaaacta acagaaaaaa caataggaga ttcaatcagt gctaaatatt gttcgagatt
     8581 ttgtttagtt tctttgtcta acatatccac cacctaaatc tttccaacaa gatcaaaact
     8641 tggtttcaat gtttcgccac tttctttcca ttttgccgga caaacttcac ctgggtgggt
     8701 acgtacatat tgagcagcgc gaatcttatc aatcagtgca ctagcgtcac gaccgattcc
     8761 atctgcattg atttccatag cttgaacgat tccgtctgga tcaataataa atgttcctcg
     8821 ctgagctaat ccttgctctt catccaaaac atcaaaaata cgagaaatct gatgagacgg
     8881 atcaccgatc atcacgtatt cgattttacc gatagcatct gatgtatcat gccatgcttt
     8941 gtgagtaaag tgggtatcgg tagagcaaga aaagacttca acacctaaag atttcaatgt
     9001 actgtattgt tcttgtaagt cttctaattc agtaggacaa acaaaagtaa aatcagctgg
     9061 atagaagcaa agaatactcc agttccccat aagatctttt tcactgactt ctaaaaattc
     9121 tccttgatga taagcatgtg cattaaattc ttcgattttt ttcccaatca atgacatagt
     9181 aaaacctcca ataataatta tttatttata attattgtaa tttagttgga gttgcaaagt
     9241 caatggatat tttgttattt aataaagatt actcaaaaac gaaggttaat tataaaaata
     9301 gaagaggtcg caagaaaatg ctactgctgg aaatactcgg gataacgttg agtaacagtt
     9361 tcctgttctt tcagcatcat gtgtaagtgc aatcccgttt gaaatcgagc ttcttctggt
     9421 tttttatcaa ctaaagcctt gagtaaatca taatgttgtt ccatgatcgt ttcccatgga
     9481 agcccctgaa tggtcactcg taaccagcgg aaacgttcta aatgggtatt atggtcatct
     9541 aaccagttcc aaacttcttt tcttcctgca atttcgaaac aagcttcatg aaataaatta
     9601 tctgcacgga aaaaagcgcg ttcgtcattt attttgactg ctttttcttg ttcttctaaa
     9661 atcgtttcta gcactattcg tgtttgtgtg tccaatttgg aacaacattc aatcatgatt
     9721 tgctcttcca actgttctcg gacaaagcga gcattttctg cagaaacaag attaattttt
     9781 gaaacatacg taccactttg aggtatcgta tacacgagtt cttgctgacg tagttgaatc
     9841 aatgcttcgc gaatgggagt ccggccgata gcaagatgtt cctccagtgc cttttcagat
     9901 attttccttc caggttctaa gtcagcatag ataatttgtt tacgaatcgc ttgataagct
     9961 tgagattgca agctgctttt catctttatt cctccaaaat catttctatg aacgtagtat
    10021 aacagaagag gtctgaaaaa caatctggta tgtcacatta actagtaaat ttgtataaat
    10081 agtaaaattt tggttgacat agcgattttt attgcataaa attcacttga atacaaaaac
    10141 taatatgtta gtttaggagg ggaaaaatga ttgatttaaa caactggagg aactttatcc
    10201 ctgaattatc tcaaaaagaa gtagaaatac ctcattttga ccgtgcatca ttaagagaaa
    10261 atggacaaaa aaatcctgtc tggatccatt tcggtggcgg aaatctttat cgaggatttc
    10321 atgcagaaat cgctcaacgt ttagcggatc taggcgaatt gtccactggt gtcattgttt
    10381 gtgaaacatt cgatgaagaa ataattgaaa gggcttacca agattttgat gatttgattc
    10441 ttgaagtggt catgccaagc agtggagagt tcgtcaaacg tatattagct gcgacagctg
    10501 acagtctgta ttgtcatcca gattgttctg aacactttga taagatgatt cgacactttg
    10561 aaaatcctag tttacaatta gttacttttg ctattactga aaaaggttat cgattgaaag
    10621 atacaaataa taaatatata ggaccgattg cagtcgatat aaaaaatggt ccaaagaagc
    10681 catcacatac aatgagtatt cttgctgcgc tactttataa acgtttttta tctggagctt
    10741 ggccgattgc acttgtctct acagataatt tttcacaaaa cggtagtcaa ttacgtactt
    10801 ctttgctaac gatcgcaaaa gaatggcaaa aggaaggtta tgtacaaaat acatttatcc
    10861 aatacttatc gaatgaagaa attgttgcgt ttccatggac gatgattgat cgtatcaccc
    10921 cgaatccttc cttgtcagtt agcaaaatgt tggcaaaaga gggcttttca aatatgtcga
    10981 ttttccaaac cgcaaaagga aataatattg ctccatttgt caatacagag gacatccatt
    11041 atttaatcat ggaagatcat tttcccaatg gacgtccgaa attcgaaaaa gctggagtat
    11101 tcttgactga tcgtgcaacg gtagataaag cagatacgat gaaggtgacg acttgcctta
    11161 atcctttgca tacgtcttta gctattatgg gttgtttact ggggtatagg agcatagctg
    11221 aggagatgaa agatccagat ttatcgctgc tagtttctga aatcgggtac aatgaaggcc
    11281 tcccagttgt ggagtctcca ggtatcattg atccaaagat ctttctggaa gaagtaatta
    11341 ctgtgcgctt ttctaatcca aatattcctg atatgcctca gcgaatcgcc acggatacct
    11401 ctcaaaaggt ggcgattcgt tatggtgaga cgattaaaaa atatatggaa atagaagtta
    11461 aagacccgca gacacttgta ttcataccat tgactctcgc tgcttggctt cgatacctta
    11521 ttggcattga tgatcaagga aaaccattca tcccgagtcc agacccacta ttgacagact
    11581 ttcagcataa gctttccgat attcaactgg gtacgcaaga tacatcacat attcatgaga
    11641 aaatggctcc tattttgtca aataaagaaa tttttggtgt agatctttac caagcagagc
    11701 ttggcagaaa aatagaagaa atgttcatca agatggtagc aggaccgaat gccgtacgaa
    11761 aaacattaca ggattactta caagaacatg gaggaaattt atcatggaaa tgacttttag
    11821 atggtacgga tcacaggaag aaaagattac cttagatgaa atcagacaga ttcctgcggt
    11881 caaagggatt gtaggcacat tgatggatat accagtagga gaggtatggc ctagggagag
    11941 gatcaaagaa ctaaaagaag aaattgagtc tcgtgggtta acactaaaag taattgaaag
    12001 cgtcaatgtg catgatgcca ttaaaattgg attaccttcc cgtgagcagt atatcgaaaa
    12061 ctataagcag acaatccgaa acttggcaga atatggaata gaagtcatct gctataattt
    12121 tatgcctgta tttgactggg tgaaatctga ccttgactac cgcttagaag acggctcatc
    12181 cacgttagct tttatatctg atgatattcc agatgatcca agagaaatcg tcgcgcgcat
    12241 cgaacattcc agcaatgaat ttgaattgcc gggatgggaa cctgagcgct tagctcatat
    12301 caaatccttg cttgaagcct atgcatcagt agacgaagaa aaacttcgag aaaattttgc
    12361 ctattttctc caatcaatca tcccaacatg tgaagaggta ggggtcaaaa tggctgtaca
    12421 tccagatgat ccgccatact cgatttttgg attacctcga atcgtaaaga atcgagaaga
    12481 tttagattgg ttgtgccgca tagtagacag cccttataac ggaatcactc tttgtacagg
    12541 gagtattgca gaagatccag aaaatgatgt atatgggatt ttagcagaat tttgtcaaag
    12601 agatcgaatc ccatttgcac atgttcgaaa tattaaattt ttagctaatc gagatttcta
    12661 tgaggcaccg cataaatccg aatacggttc attagacatg taccgcatac taaaaacaat
    12721 gtatgacaac ggatttaacg gatacatccg tcctgatcat ggaagaatga tctggaatga
    12781 gacaggaaga ccaggatacg gcttatatga tcgagcatta ggtgctgttt atctaaatgg
    12841 attatgggaa gcaatcgaaa aaggaaacaa aagtaaagat aattagtgaa aaaaactgta
    12901 attttattat gtaaataaga aggatgttca aattc
//
LOCUS       DACGEU010000076        12807 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.077, whole genome shotgun sequence.
ACCESSION   DACGEU010000076 DACGEU010000000
VERSION     DACGEU010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12807)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12807)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12807
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.077"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(8..325)
                     /locus_tag="IXR40_002105"
     CDS             complement(8..325)
                     /locus_tag="IXR40_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361936.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMQTKNPKTRKKPKFKVGDMVRCEA
                     EGFIYPFRGYVEHVYNHSAIIRIENTMECDKLLAKSKENLAVVRLVDMEVINNDCKWE
                     EMR"
     gene            complement(322..525)
                     /locus_tag="IXR40_002106"
     CDS             complement(322..525)
                     /locus_tag="IXR40_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PIN"
                     /protein_id="HAQ4361937.1"
                     /translation="MNNRHRRITKLRKQELNVLKTKFEKEYGVSAEETYKVASQCVAD
                     ASDAIRKFGISILSDDRKWEEKE"
     gene            complement(549..854)
                     /locus_tag="IXR40_002107"
     CDS             complement(549..854)
                     /locus_tag="IXR40_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361938.1"
                     /translation="MNIKVYLKRNLARFPRSWDTNSYPFEVEEESYLMSANMIEITRD
                     DADEFDKKRSWYSVSNPMYTAVIEDYHISDRFILVDLERPKKRIKQYRRCGFSTKKW"
     gene            complement(851..1072)
                     /locus_tag="IXR40_002108"
     CDS             complement(851..1072)
                     /locus_tag="IXR40_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361939.1"
                     /translation="MFKIAFYLFDYKDDSFKKVYFHHWNDSKPVFTKNKRRAQEYFDE
                     RSANKDIVQLKKAESPSAKTLSIRLEEKE"
     gene            complement(1073..1411)
                     /locus_tag="IXR40_002109"
     CDS             complement(1073..1411)
                     /locus_tag="IXR40_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361940.1"
                     /translation="MIILATDYIDSLKDENGNVPALLNCGIKSKNRIILLRISADLAK
                     YLYLSKTAVYYTAATRYQYKGKTISQDYYDRLISPDMHGKSKSAIKLFGAIEIYADDF
                     PNLWLKEEAE"
     gene            complement(1408..1821)
                     /locus_tag="IXR40_002110"
     CDS             complement(1408..1821)
                     /locus_tag="IXR40_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361941.1"
                     /translation="MIPRFRAWNKKTQSFIDYGDLVLDLRSGKIYAGDIGLVESTIDV
                     TDQIELMQSTGLKDKNGIEIFEWDIVSVSVRNGFDYLDNKVCVVKNSIGHSGLVCATV
                     DEDLEYQIFNTELFEEYTYEVIGNIWENSELLEVE"
     gene            complement(1988..2305)
                     /locus_tag="IXR40_002111"
     CDS             complement(1988..2305)
                     /locus_tag="IXR40_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HAQ4361942.1"
                     /translation="MDLITQYSDIILKKIMMKIQKDKKSKERAELVKLEMAETGSGVR
                     TSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVEKYKEILDEYME
                     DRE"
     gene            complement(2305..2595)
                     /locus_tag="IXR40_002112"
     CDS             complement(2305..2595)
                     /locus_tag="IXR40_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361943.1"
                     /translation="MLDMKIEDYRITSDSRNIVLSKVRRDEEGNIRYTEAKEESRADI
                     GYFQTVSSCLKAIQRDYVLSEERTIKSIIEYKKALENITRQFEQACEIEEEK"
     gene            complement(2589..2900)
                     /locus_tag="IXR40_002113"
     CDS             complement(2589..2900)
                     /locus_tag="IXR40_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361944.1"
                     /translation="MNVDKKAAMKRIIELTHSENWQEDKEIVAEVQKLGKSMWTEKPK
                     RRTPRKIAIWHGDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEKK
                     C"
     gene            complement(2897..3058)
                     /locus_tag="IXR40_002114"
     CDS             complement(2897..3058)
                     /locus_tag="IXR40_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HAQ4361945.1"
                     /translation="MTTEEVIQMRIRNIQREIDDLERTKAVMANETARKAIDLHIVNL
                     RREIRRLEE"
     gene            complement(3073..3432)
                     /locus_tag="IXR40_002115"
     CDS             complement(3073..3432)
                     /locus_tag="IXR40_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HAQ4361946.1"
                     /translation="MNKYRNKKTVHRGIKFDSIAEAEYYDLALWQAEANGWKVKLQER
                     FELMPKFELDGKKYRKIEYIPDFTFYKNGKLVKVVDVKGMQTKDFKIKAKLFCHQYQA
                     PLILAKKYRNTFKEERF"
     gene            complement(3429..4280)
                     /locus_tag="IXR40_002116"
     CDS             complement(3429..4280)
                     /locus_tag="IXR40_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAQ4361947.1"
                     /translation="MESLANAMEKLIRRVLVQSGKCPECSEPLYSWRAKNKDGSERCK
                     PTCMSCGYKALRVKEDIQTERIYNDSLKARALSFFQNGSVLTDKTLFKCKMENYHVVD
                     QETKIALEKAKSYTNEVLLNHPAHFILSGKSGSGKSHLSMATAWEILERSNYDKKILF
                     ISYQELLEQIKFSYNNTELRKEIEGSLIADIKTTDLVVFDDIGAELGSGVSNSRQFTN
                     NTLNTLLEARQNKATIITTNLSGPELREAYGERIVSRIFKNSEGYALKFQQTADKRIK
                     PVKGSIA"
     gene            complement(4297..5127)
                     /locus_tag="IXR40_002117"
     CDS             complement(4297..5127)
                     /locus_tag="IXR40_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HAQ4361948.1"
                     /translation="MAEISWIKLKTTMFDDEKIRLIQAVPESDAIIVIWIRLLVLAGK
                     TNDDGLIYIQRNMPYTEEMLATLFGKNVNTVRLALTTLANFNMIDLSSDGLIAISNWE
                     KHQNIEGMDKVRLKNAERNRKYRERKRQERLKLENDVSVTSRDGTDKDIEEDKDIDKE
                     EKKGKYSDEHLRLAKKLQSNLTEDFPKEMNKVDIEKWADTIRLMEERDKASIEAIEYV
                     INWLPTNEFWFGNIRSAKKLREKFEKLKFEIKADKKNHKKQSQKLQYSNPSEYDDLPI
                     "
     gene            complement(5130..5816)
                     /locus_tag="IXR40_002118"
     CDS             complement(5130..5816)
                     /locus_tag="IXR40_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361949.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDISATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGREISLK
                     DESNTTVSDANILANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHSEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     ETIKKLRIGG"
     gene            complement(5822..6493)
                     /locus_tag="IXR40_002119"
     CDS             complement(5822..6493)
                     /locus_tag="IXR40_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HAQ4361950.1"
                     /translation="MSEIKGTTNFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
     gene            complement(6486..6827)
                     /locus_tag="IXR40_002120"
     CDS             complement(6486..6827)
                     /locus_tag="IXR40_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361951.1"
                     /translation="MEKELSTLDQYLIDPDWGKPKIEETSGRKIRRNLLTNEELAWDQ
                     DDLGNHVTIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYDRDNLIDISYYGPGKK
                     YIAEMEAEFDE"
     gene            complement(7005..7703)
                     /locus_tag="IXR40_002121"
     CDS             complement(7005..7703)
                     /locus_tag="IXR40_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HAQ4361952.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNMKVMGVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDDNE"
     gene            7790..8260
                     /locus_tag="IXR40_002122"
     CDS             7790..8260
                     /locus_tag="IXR40_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361953.1"
                     /translation="MSIISFILSTFLTGIKIKGMRPQLEVELNASYFAADMIYTKVII
                     SNYSTEPAMLVNLELSSANLNRRWSATPFKKLIAKGGSVDDNRIYSEAVPLNIPPKSA
                     ISCYLAFEVGKINFNKLLNHQTKMIFTLNRTQIHKIVDIKNTNFPIEKLVKELN"
     gene            complement(8303..8482)
                     /locus_tag="IXR40_002123"
     CDS             complement(8303..8482)
                     /locus_tag="IXR40_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361954.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEAEYRAKKPTEGAD"
     gene            complement(8469..8807)
                     /locus_tag="IXR40_002124"
     CDS             complement(8469..8807)
                     /locus_tag="IXR40_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HAQ4361955.1"
                     /translation="MQYLEAKIPIPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
     gene            complement(8823..9026)
                     /locus_tag="IXR40_002125"
     CDS             complement(8823..9026)
                     /locus_tag="IXR40_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4361956.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            complement(9041..9787)
                     /locus_tag="IXR40_002126"
     CDS             complement(9041..9787)
                     /locus_tag="IXR40_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HAQ4361957.1"
                     /translation="MNTPQIFSFEQHEVRTFLENDIPYFVANDVAKTLGYKNPSKATN
                     DHCKKSIETWGNDSLGRRQKFKVIPESDVYRLIIKSNLPSAEKFEAWVMEEVLPTIRK
                     TGSYSNVPQSFAQALRLAADLEEKNQLLEQQIAEYEPKISYLDTILSSTDTVATSQIA
                     ADYGMSAIALNKLLNELGVQHKVSGQWILYRKHMNQGYTKSHTSEIPKADGGTKVVMN
                     TKWTQKGRVFIYNLLIAEGYYPQMDLEEIG"
     gene            9868..10047
                     /locus_tag="IXR40_002127"
     CDS             9868..10047
                     /locus_tag="IXR40_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361958.1"
                     /translation="MNKKTDEIAADLVVAWLNHESQVSTKGESISPKEIAQAYLDIHY
                     AVIYGQLPEDRKNDD"
     gene            10478..10798
                     /locus_tag="IXR40_002128"
     CDS             10478..10798
                     /locus_tag="IXR40_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4361959.1"
                     /translation="MITFERIKELAKKQGKSLNKVEEDLGYGKNVLYRLKNSNPSTER
                     LQEIADYFDVSVDYLLGREEKETPKHVDLSENDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            10816..11247
                     /locus_tag="IXR40_002129"
     CDS             10816..11247
                     /locus_tag="IXR40_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HAQ4361960.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFTASHFEYSVLYDTSTTFHSKFETEADKIAILILLNIYIENELTDE
                     SQFNLEKFMEYYSIQNKLRYTCYAVCQCYFKKKYSYARQYV"
     gene            11374..11958
                     /locus_tag="IXR40_002130"
     CDS             11374..11958
                     /locus_tag="IXR40_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HAQ4361961.1"
                     /translation="MAKKVMGQDGKMYKVSKPFYKKVWFWVLAVILIIIIGSALNGGS
                     DSNKASDNGGEKVTKSSTSASSSKEEKSDTFYKIGDTVKVGDAEYTLNSVELTDERNQ
                     FEENQPAQVVKITYTVKNDGDSDIPVGTDVEVYGPDDKKSETYANENTMGSVAPGKQM
                     DVTAHFTLNQKGEIEIHFSPLVSFEKAAIFKATV"
     gene            12072..>12807
                     /locus_tag="IXR40_002131"
     CDS             12072..>12807
                     /locus_tag="IXR40_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAQ4361962.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQHFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETS"
BASE COUNT         3660 a         2537 c         2003 g         4607 t
ORIGIN      
        1 aattccttca tctcatttcc tcccatttac aatcattgtt tataacctcc atatccacca
       61 atctcaccac tgctaaattc tctttgcttt tcgctaataa cttgtcgcat tccatcgtgt
      121 tttcaatgcg aatgatcgct gagtgattat agacatgttc tacatatcca cgaaatggat
      181 agatgaaccc ttctgcttcg cagcgaacca tgtcaccgac tttgaatttt ggtttcttac
      241 gtgttttagg gttctttgtc tgcatatcca gcattaaacc gccgataccg tggctactag
      301 cgtaaaatcc gtcttttagt ttcattcttt ttcctcccat ttacgatcat cacttaatat
      361 cgaaattcca aacttacgaa tagcatcact tgcatcagca acacactgac ttgccacttt
      421 atatgtttct tctgcagaaa ctccgtattc tttttcaaac tttgtcttta gtacattcag
      481 ttcctgtttt cttagttttg ttattctgcg atgtctgttg ttcattctga gtcacctctg
      541 ttttgttttc accatttctt tgttgaaaac ccgcaacgtc tatactgttt aattcgtttc
      601 ttaggtcttt ctagatcaac cagaataaat ctgtcggata tatgataatc ttctattaca
      661 gccgtataca ttggattcga aaccgagtac catgatcttt ttttatcaaa ctcatccgca
      721 tcatctcttg taatttctat catgttagca gacattagat agctctcttc ttctacctcg
      781 aatgggtagg aatttgtatc ccagcttcga ggaaacctgg ccaaatttct ttttaaataa
      841 actttaatat tcattctttt tcctccaatc gaattgacaa tgttttcgca gatggtgatt
      901 ctgctttttt taactgcact atatctttat ttgctgatct ttcatcaaaa tactcctgag
      961 ctctcctctt gttttttgta aaaactggct tgctatcatt ccagtgatgg aaataaactt
     1021 tcttaaacga atcatctttg taatcgaaca gataaaatgc tattttgaac attcattccg
     1081 cttcctcctt caaccataaa tttggaaaat catcggcata tatctctatt gcgccaaata
     1141 acttgatcgc tgattttgat tttccatgca tgtcaggact gattaaacga tcataataat
     1201 cctgactgat tgtttttccc ttgtactgat aacgtgtagc cgcagtgtaa tatactgctg
     1261 tcttgctcag ataaagatat tttgctaaat cagccgatat ccgtaacaaa atgattctat
     1321 tcttgctttt aattccacaa tttagcaatg ctgggacatt cccattttca tcttttaaag
     1381 aatcgatgta gtcagtagct aagataatca ctctacctcc aataactcgc tattctccca
     1441 aatatttccg atgacttcat acgtgtattc ttcaaacagc tctgtgttaa aaatttgata
     1501 ctctaaatct tcatcaacag tggcacacac taatcccgaa tgtcctattg aatttttgac
     1561 aacacaaact ttattatcta aataatcgaa tccatttcgc acgctgactg atacaatatc
     1621 ccactcgaaa atctcaatgc cattcttatc tttcagccct gttgattgca tgagttcaat
     1681 ttggtcagtc acatcaatgg tgctttccac taacccaatg tccccagcgt aaatttttcc
     1741 gcttctcaaa tctaaaacca aatcaccata atcaataaat gactgagttt tcttattcca
     1801 cgctcgaaat ctcggtatca tttgctgtcc tccttctgta actcgccgta aattgaacat
     1861 ctacggcgaa ttgcttttac tctgcgttca ttttcgattg tgggccgaat ttcgtatgtt
     1921 ctttttgcca ttttcaattg atttctagca cctcttaatg catctgaata gatttctttt
     1981 ggcatcatca ttctctgtcc tccatgtatt cgtctaatat ctctttatat ttctctacaa
     2041 atttgaaacg atcttgatga agtttcttgc tccaatttgt ttgccgatcc agctcacgca
     2101 tctgatcgaa ccctttttga atttcgttgt aatagaattc aatgtttgct gctgctttcc
     2161 aatgcctcga tgttcgaact cctgatcctg tttcagccat ttctaactta actaattccg
     2221 ctcgttcttt tgattttttg tctttctgaa tcttcatcat gattttcttg aggatgatgt
     2281 cactgtattg tgtaatgaga tccattattt ctcctcctca atctcacatg cctgttcaaa
     2341 ctgtctagtg atgttttcta acgctttttt gtactcgata atacttttta tcgttctttc
     2401 ttcacttaac acgtaatcgc gttgtattgc ctttaaacac gatgagacag tttgaaagta
     2461 tccgatatct gctcgtgatt cttcttttgc ttcggtgtag cggatatttc cttcctcatc
     2521 tcgtcttacc ttcgatagga caatgtttct agaatcactg gtaattcgat aatcttcgat
     2581 tttcatgtct agcatttttt ctcctccaca tacctaaact gtcgtccttt tgaatcaatc
     2641 cataagctcc tagctctatc ccagatgatg tttttgctca gaccagtaat ttcagataac
     2701 tgttcagcgg tacctgttac taaaattcgg tcaccatgcc agattgcaat ttttctcggc
     2761 gttctccgtt tgggcttttc agtccacatt gatttgccga gcttttggac ttctgcaact
     2821 atttctttgt cttcttgcca attctcagaa tgtgtcagtt cgatgattcg tttcattgct
     2881 gctttcttat ccacgtttat tcctccaatc tacgaatttc ccttcttaaa ttcactatgt
     2941 gtaaatcgat tgccttcctt gccgtttcat tggccatcac tgcctttgtt cgttccagat
     3001 cgtcaatttc acgctgaatg tttcgaatac gcatttgaat cacttcttct gttgtcatga
     3061 tggaccacct cgttaaaaac gctcttcctt gaacgtattc cgatattttt tagctaatat
     3121 caacggcgct tgatattgat gacagaacaa ctttgccttg atcttaaagt cttttgtctg
     3181 cattcctttg acatctacga ctttgacaag tttgccgttt ttataaaatg tgaagtcggg
     3241 aatatactcg atcttgcgat acttctttcc gtctagttca aatttcggca tcagctcaaa
     3301 tctttcctga agttttactt tccagccatt tgcttcagct tgccacaagg ctagatcgta
     3361 atactctgct tctgcgatag aatcaaactt gatacctcga tgaacagttt ttttattacg
     3421 gtatttattc atgcgatact acctttcact ggttttatgc gcttgtctgc tgtttgttgg
     3481 aatttcagcg cataaccttc tgaattctta aatatcctag aaacaattct ttcaccgtag
     3541 gcttctctta gttcaggacc agataagttt gttgtgatga tcgttgcctt gttctgtctg
     3601 gcttctaaga gcgtgtttaa cgtgttgttt gtaaactgcc tactatttga taccccacta
     3661 cctaattcag ctccaatatc gtcaaaaacc accaaatcag ttgttttaat atcggctata
     3721 agcgatcctt caatttcttt tctcagttca gtattgttat aagaaaactt tatttgctct
     3781 aataattctt gatagcttat aaaaagtatt ttcttgtcat aatttgagcg ctcaagtatt
     3841 tcccaagctg tggccattga taagtggctt tttccgcttc ctgatttccc tgatagaatg
     3901 aaatgtgcag gatggttcag cagaacctca ttcgtatagc tttttgcttt ttctaaagcg
     3961 atttttgttt cttgatccac tacgtgataa ttttccattt tgcatttaaa caaagtttta
     4021 tctgttaata ccgaaccatt ttgaaaaaaa ctcaacgctc gtgcttttaa gctatcgtta
     4081 tatatccgtt cggtctgtat atcctctttc acacgtaacg ctttataacc acaactcatg
     4141 catgttggtt tacaacgttc tgaaccatcc ttatttttag ctcgccaact atacaaaggt
     4201 tcgctacatt ctggacattt tccgctttgc actaatactc ttcttattag tttctccata
     4261 gcatttgcta ggctttccat gtgatgcatc tcctttttaa attggcaagt cgtcatattc
     4321 actaggattg ctgtactgta gtttttgact ttgcttttta tgattcttct tgtctgcttt
     4381 gatttcgaat ttgagcttct caaatttttc tctcaatttc ttagcacttc taatatttcc
     4441 aaaccaaaat tcatttgtag gtagccaatt gatcacatac tcaatcgctt ctatagatgc
     4501 tttatctctt tcttccatca acctgattgt gtctgcccat ttttcgatat ctactttgtt
     4561 catttctttt ggaaaatctt cagttaaatt actttgcaac tttttagcaa ggcgtaagtg
     4621 ttcgtcagaa tacttacctt tcttttcttc tttatctata tctttatctt cttctatatc
     4681 tttatctgta ccgtcacgtg acgtcacgct aacgtcattt tccaatttga gacgttcctg
     4741 tctctttctt tccctgtatt tacggtttct ttcagcattt tttagcctta ctttatccat
     4801 accctcgata ttttgatgtt tttcccaatt actgatggca attagtccat cactgcttag
     4861 atcaatcatg ttgaaatttg ccaatgtagt tagcgctaag cgaaccgtat ttacgttttt
     4921 gccaaacaat gtagcaagca tttcttcggt ataaggcatg ttcctctgga tatatatcag
     4981 accatcgtcg ttagtctttc ctgctaaaac tagtaatcga atccatataa cgatgatggc
     5041 atccgactca ggaacagctt ggattaatcg tattttttca tcgtcaaaca tagtagtttt
     5101 aagtttgatc caacttatct cagccaaatt tatcctccta tccttaactt tttaattgtt
     5161 tcctggttta acttgatccc tttgatttga tatttatttt tgaaattgat cacacctatt
     5221 ttgtgtttct ctgtgtgatg gattctgcag agtgctgcaa atgtgtactc tgaatgatca
     5281 acttctttgc gctttcgtct tcccagcgct ttgtcaaagt gatcgatatc agctcctgtt
     5341 ttgccacaga tgcagcagac tctttttgta atgcatttgt agaagtaata ctcttgattc
     5401 gctggtaaaa tctcatatcc ttctttgaaa ggaatatgat gttcaaagat gaaatctagg
     5461 atgatattcg ctaagatatt ggcatcactc acggttgtat tcgattcgtc tttgaggctt
     5521 atttcgcgcc ctgtgacacc ttcaaaacgg aagtagaaga attccttcca gaagtccgtt
     5581 ggcatgcctg tatcgatgaa aatatcgcct atgagcgcat agatgaagtt tctttgctgt
     5641 actgtgaacc gtctaggatc aataaaacga atttcaatga ctcgatcacc atcgtagccg
     5701 tcatacatcg tctttagtcg atcaatgttc acttcctcat tgatggttgc gcttatgtct
     5761 tttcctttga actttttcag aaccgctgaa tatgaatcga ttaatggttt aaacactcat
     5821 atcacttctt atctaattct tttctcttag ctgctattgc tcgctccatc aaggcacatt
     5881 gctcatagct taactgttca atagtttcaa cgttatcagc taagagccct aatttatctg
     5941 tctgctcatt aacatattcg attaaggttt tggtcatatc tttacccatc tgctcattga
     6001 aagcttctag aatcgtctct agcatgttta atttctttgt atcgattcta ggtggtgttg
     6061 gaatatcttc cccttgaaat acatataatc ccagtccgtg tagagccaat gctttcacaa
     6121 agcatcgctt caatgagtta ttgatttgca ttgcatttgg tttaacaact ggttggtttc
     6181 gataatctaa aacaggaaat aattcggttt ccgtgtgtcc tttaaccgtt actgagacag
     6241 atacataagt cccagtttca tccataagaa aaggtttata ttcctcaaca agaaagtctt
     6301 gatgagttcc agaaacaacc ctgtagtgtt tgtactcatt aatagttacc gttgcctgtg
     6361 gatcattctt tttcataatc tcccacgcgt gagcccaaga taaataatca aaatttcctt
     6421 ttttcttgag aattttattt aacttacgac taaaaagttt ttcaaagttc gttgtccctt
     6481 tgatttcact catcaaattc tgcctccatt tcagcaatgt atttcttacc tggtccgtaa
     6541 taagagatat caatcaagtt atctctgtcg tactcttcta gcgcatcaat caagccatct
     6601 tcgatgacgt aaatatattc aggtttattc gaatgcttcg atagatggat aagataaaca
     6661 tgatcccaaa tagttacatg gttgcctaaa tcatcttgat cccaagctag ttcttcattc
     6721 gtcaaaagat ttcgtctgat ttttcgacca cttgtttcct caattttcgg cttgccccaa
     6781 tcaggatcaa tcaaatattg atctagagtg gaaagttctt tttccatatg ctaaaatctc
     6841 cttatgatgt gttttctttg tgactctttg cttgccggcg gagtcacttt tttatttgtt
     6901 gccatgcttt ttgcttgtca atatgttgtt ggcttaggat gattggttta tagtatttcc
     6961 accagcaatt agcaattgcc gtccctattc ttagcgcttc agctctattc attgtcatca
     7021 ccaaaaagtc tctgttgtct gttcagttga tcaatttcca tacggatcgc agtttctggc
     7081 aaccacattt caataaatga aacagcatca tcgaatctct tacgaggtaa ctcgccatat
     7141 cttgggattg aaaaggtacg tttaaattca gaccaaaatt ttgagaatac ttttttgctg
     7201 atttcttcat aagctcggct ttcttttccc cctagaactc ccataacttt catatttcct
     7261 ttttgcttaa tttcaaactc ttgttgtccg ctaattcgca tagtatcttt aagcatggaa
     7321 acatcttttt taacatcttt catttcttct aattgataga tcatcatatc ttcaattgtt
     7381 tgaggaacag tattcttgcg aataacatct tccatttcgt tgaatgcttc aatgtatttt
     7441 tgtttgaagt agatagcttt ctttcctgta aaccccatag ccagcaagaa aaatccatct
     7501 ctactaatga agaaaactcg tcgatttctg ccatatgaat ctggttcatt accttctaca
     7561 aacatctgtc caaaattgga cacatctttt tttagtgcat caatatctct taaaacatgt
     7621 tgatgttttt tctcgaagct ttctgccact tgtaagctcg tagtcacagc ttctttattt
     7681 ttcaaaatta ctaattcttg cattatttct tctctccttt ttggtataat ttagttaaaa
     7741 actggtggtg tttattttga atttttttca cttaacaatt tttcaatgga tgtcaataat
     7801 aagttttata ttgagtacgt ttttaacagg gataaaaata aaaggaatgc gccctcaact
     7861 agaagttgaa cttaatgctt cttacttcgc tgcagatatg atttatacaa aagtaatcat
     7921 ttctaactat tcaacagaac cagctatgtt agttaattta gaactttcat ccgctaactt
     7981 aaaccgcaga tggtcagcta ctccatttaa gaaattaatt gctaaaggag gatcagtcga
     8041 tgataataga atatactctg aagctgtacc gctaaatatt cctcctaaaa gtgctatatc
     8101 ttgttacctt gcatttgaag tagggaaaat taattttaat aaactcctta atcaccaaac
     8161 aaaaatgata tttactctaa atagaaccca aatccacaaa attgttgata tcaaaaatac
     8221 aaacttccca atagagaaat tagtgaaaga attaaactga gtaatagtaa tatacattct
     8281 agtttctctt ttctattcat ttttagtcag ccccctcggt tggctttttc gctctgtact
     8341 cagcttcagc ttcatcaagc cccataaaaa tccaaaccat gtaaacaatc gttcctatca
     8401 acgcttgcct gcttccccaa agtcctaaag cgtagatgat tagcggtgcg ctgaacacta
     8461 gcgctctatt aaattttccc atccgcttgc ctccttaaga tttccgaaaa atttgtttct
     8521 aaaaattcaa gtgttttact tcttaaaaat agatatgtgt ctcttccttc aactggataa
     8581 tagacaaatc catttttgtt tttctcgata tcgataatat ttctatatct tgggttcttt
     8641 aaaactctag aagtaaacca atcatatttt ctgttaatcc gttctagcac ttctggcaac
     8701 gtcatccatc taccagtatc atcagctttt tttaactcct cataatccac ttgggagata
     8761 attacatagc cttctggaat tgggattttt gcttctagat attgcattag ctgttcctcc
     8821 ctttacaatt cgtacatagt gataatcgaa tctataattc tgtttgcttc tgcagaagtc
     8881 tttttaccgt ttaaaattaa agataagtag cttttgctaa ttccaaatct ttcagcaagc
     8941 atggtgtaag ttaagaactt tgaactttcg acatattctt tgattttttc tctatctcgt
     9001 tgagtgattt ctgcaatgtc agtcatacta aaactccttt ctaaccaatt tcctctaaat
     9061 ccatttgagg gtaatagccc tctgcgatta ataagttgta aataaacact cgccctttct
     9121 gtgtccattt ggtattcatt acaactttag tgccgccatc ggctttcgga atctcacttg
     9181 tgtgcgattt tgtgtatcct tggttcatat gttttcggta aagtatccat tgtccgctaa
     9241 ctttatgttg aacacctaac tcgtttagca atttgtttag agcaattgcc gacattccgt
     9301 aatcagctgc aatttgagaa gtagctaccg tatctgtcga tgaaagaatc gtatctaagt
     9361 agctaatctt tggttcgtac tcggcaattt gttgttcgag taattggttc ttttcttcta
     9421 aatctgctgc taaacgcaat gcttgtgcaa aactttgagg tacgtttgaa tagctacctg
     9481 tttttctgat tgttggaagg acttcttcca ttacccaggc ctcaaatttt tcagcgcttg
     9541 gtaagttcga tttaataatc aagcggtaaa catctgattc tggaataact ttgaattttt
     9601 gacgacgacc taacgaatcg ttaccccatg tttcaattga ttttttacaa tgatcattgg
     9661 tggctttact gggatttttg tatcccaaag ttttggcaac atcgtttgct acgaaatacg
     9721 gaatgtcatt ttctagaaac gttcttactt catgttgttc aaaactaaaa atttgtggtg
     9781 tgttcatttt tgttcattcc tttctttgat ataattttct tatcagtaag tggtctactg
     9841 aaataatgca taaggtggtg aataagtatg aataaaaaaa ctgatgaaat cgctgcggat
     9901 ttagttgttg catggctaaa tcacgaatca caagtatcta ctaaaggcga atcaatttcg
     9961 ccaaaagaaa ttgctcaagc ttatttagat attcattatg ctgttatcta tggtcagctt
    10021 ccagaagacc gtaaaaacga tgactaaacg tgagctaaaa tctctgctat ggctgcaacc
    10081 atggcagagt cttctttatc taccgcgtgt tccatcgcca cttttgcttg tttcagtatg
    10141 tctaatttca aatcttcgat ttttgccgag actgtttttt ccatattctt ctctcctttc
    10201 ttttatattc gtaaacaaat ttaacaactt ttaaaaaaac tgcgttgact aaattaacat
    10261 acagtgttaa aatcagaaca tagttaaata agacatataa acattgattt taaaagcttt
    10321 cttggcggtt ggcatttatt aatcaatagt gttttttgtt gtctttttag ttgttaaact
    10381 tgtttacaag aatgatatta acaccttttg ttaaaatagt caacgaattt taacaaataa
    10441 agttaaatat tttttcttga acgaaaggaa tattgatatg ataacgtttg agagaataaa
    10501 agagttagcg aaaaaacagg gaaaatcatt aaataaagtt gaagaagacc taggctatgg
    10561 taaaaacgtc ttatatagac ttaagaactc aaacccctct acagaacgtt tgcaagaaat
    10621 tgctgactat ttcgatgtct ctgtagacta tcttctgggg cgcgaagaaa aagaaacccc
    10681 taaacatgtg gatttatcag aaaacgatac tgttttttct tttgatggaa aagaaatatc
    10741 taaggagaca atgcgtaaag cgattgcaat tgctaaagct ttagaggaaa atgaatagtt
    10801 ggagtgatgg gttgtatgta tttgaaattg aaagaaatgt tgagcgaata caatttgaaa
    10861 gtagtttaca tggaaatgaa agagcctggc ttctattatc cgaagcctag aatcattttt
    10921 ttgaatgaaa atctatatgg cgaaactgca gaagcctttc atttatctca tgaacttgcg
    10981 catttcaccg cttctcattt tgaatattca gttttgtacg atacttctac aacttttcac
    11041 tcaaaatttg aaacagaagc agataaaata gctattctaa ttttattaaa tatctatatt
    11101 gagaacgaac tgactgatga atctcagttt aatctcgaaa aatttatgga gtattattct
    11161 attcagaata agctcagata cacttgttat gctgtctgcc aatgctattt taagaaaaaa
    11221 tattcttacg caaggcaata tgtatgaata catcaagaat tattaaaaaa accgatttca
    11281 gcaaaacatt aaaaaagccc gtgctggcac acggactcat acctcatttc tgagatcgca
    11341 aatatattat aacaagaagt gaggaatatt taaatggcaa aaaaagttat gggtcaagac
    11401 ggaaaaatgt ataaagttag taaacctttt tacaaaaaag tatggttttg ggtattagca
    11461 gtaattttaa ttataattat tggttctgct ttaaatggtg gatcagatag taataaagca
    11521 agtgataatg gtggcgaaaa agtaactaaa tcttcaacct ctgcttcatc ttctaaagaa
    11581 gaaaaaagcg ataccttcta taagattggt gacactgtaa aagttggtga tgctgaatat
    11641 acactaaata gtgtagaact aactgatgaa agaaatcaat ttgaagaaaa ccaacctgca
    11701 caagtagtaa aaattactta taccgtaaaa aatgatggcg attcagatat ccctgtaggt
    11761 acagatgtgg aagtatatgg accagatgac aaaaaatcag agacatatgc caacgaaaat
    11821 acaatgggat ctgttgctcc aggaaaacaa atggatgtaa ctgctcattt cacgttaaac
    11881 caaaagggag aaatagaaat ccacttctct cctttagtat catttgaaaa agcagctatt
    11941 tttaaagcaa ctgtataata aataaaaaac acgcccaccg tccaaagcaa gcgtgttcta
    12001 agaaaaacaa acctatacag taggcttctt tatagtgcct attgtatcag agaaagagag
    12061 tagattcaat tatggcaaga ttagtcaaac gtggaaatag ttggcaatac gaaatttcat
    12121 acaaaaaaga tgacggaaaa tacacgaaga taagaaaatc aggatttaag acaaaaggcg
    12181 aagcaaaaga tgccgccaac gaattagaat ataacttgaa caaaggcctt aaaggggatc
    12241 gcaaaaatct attattatca gattactttg aggattggat gcaactttat aaagaaggaa
    12301 cagtatctcc tatcacttat agaaaatacg aagatacgtt aatgaacata aagaaatata
    12361 tgccagcggt attgatttct gatttagata gagttggata tcaacacttt ttaaataagt
    12421 atgcgaaaga ccatgtaaaa tccaccgtta ttaagtttaa taaccatatt agagcatcgt
    12481 tgaaagatgc cgtagaagaa ggattaattc cgtttgatcc aactagaaaa gcagtaatca
    12541 aaggaaaaga ttcattgaag ccaaaagaag ataaatattt agattatgat caatttaaat
    12601 ctttaatgaa actcgtagaa gaaaaccttt ctgcgcagta ctcttctcct atgctcgtgt
    12661 tagttgctgg tgctactgga atgcgatttg ctgaacttct aggattaaca tgggaagata
    12721 tcgatttcga agatcaaatc atcactatta ataaaacatg gaattataaa ttaaatgaat
    12781 ggggaaaaac aaaaaacgaa acttcaa
//
LOCUS       DACGEU010000077        12740 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.078, whole genome shotgun sequence.
ACCESSION   DACGEU010000077 DACGEU010000000
VERSION     DACGEU010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12740)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12740)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12740
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.078"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            99..542
                     /locus_tag="IXR40_002132"
     CDS             99..542
                     /locus_tag="IXR40_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAQ4361963.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(548..1732)
                     /locus_tag="IXR40_002133"
     CDS             complement(548..1732)
                     /locus_tag="IXR40_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HAQ4361964.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            2000..2698
                     /locus_tag="IXR40_002134"
     CDS             2000..2698
                     /locus_tag="IXR40_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HAQ4361965.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            2705..3382
                     /gene="nth"
                     /locus_tag="IXR40_002135"
     CDS             2705..3382
                     /gene="nth"
                     /locus_tag="IXR40_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HAQ4361966.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(3508..4041)
                     /locus_tag="IXR40_002136"
     CDS             complement(3508..4041)
                     /locus_tag="IXR40_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361967.1"
                     /translation="MVLNNFLKEGFILSYLIVCLIIIICLHHLFLSKTIPRYSKNKKA
                     EKFCLLLNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFL
                     MSLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYI
                     GYFPNKNNNFYFYRNKL"
     gene            complement(4338..6719)
                     /locus_tag="IXR40_002137"
     CDS             complement(4338..6719)
                     /locus_tag="IXR40_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HAQ4361968.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(6709..7356)
                     /gene="recU"
                     /locus_tag="IXR40_002138"
     CDS             complement(6709..7356)
                     /gene="recU"
                     /locus_tag="IXR40_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HAQ4361969.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            7420..7959
                     /locus_tag="IXR40_002139"
     CDS             7420..7959
                     /locus_tag="IXR40_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HAQ4361970.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            8049..8468
                     /gene="gpsB"
                     /locus_tag="IXR40_002140"
     CDS             8049..8468
                     /gene="gpsB"
                     /locus_tag="IXR40_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HAQ4361971.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            8490..8857
                     /gene="rnpB"
                     /locus_tag="IXR40_002141"
     ncRNA           8490..8857
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="IXR40_002141"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            9066..10232
                     /locus_tag="IXR40_002142"
     CDS             9066..10232
                     /locus_tag="IXR40_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HAQ4361972.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            10278..11774
                     /locus_tag="IXR40_002143"
     CDS             10278..11774
                     /locus_tag="IXR40_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HAQ4361973.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     SLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            11855..12538
                     /locus_tag="IXR40_002144"
     CDS             11855..12538
                     /locus_tag="IXR40_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAQ4361974.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
BASE COUNT         4274 a         2229 c         2630 g         3607 t
ORIGIN      
        1 tttcttggtt tcagattggg ttttcctaca aaatattttt atctttgttg aataggaaac
       61 aaaaaaacaa tataatgaaa gaaaaagaag gtgtagaaat ggataaaaga caactgctaa
      121 tagaagaata tctggattta gctaatgaga ttattcatcg taataaacca gaaatggaaa
      181 aagaatttgc aggatttact ctaaatgaac tagaagtgat tgaacatatc gggaaaatcc
      241 ctgatcctaa cgtgacaaaa ttagcgaatg ctagttacat gactagagga gccatcagta
      301 agctaacaaa aaaactgata gctagaggga tcataaacac ttatcaaagc gaagagaata
      361 aaaaagaaat ctattttcaa ttgacgccaa tcggacaaaa aataaggaat agacacgagc
      421 aactccatca aaaatgggta cagcgagatg ctactgtatt tgaaaatatg tcaaaagaag
      481 aatttgacac agtatttcgt tttatcggtc gatacagaga atttatacga agtagcaaat
      541 gaagctacta ttttttattg tagtgataat aggcaaaaat cataagcaaa aatccgaata
      601 ccgtcggaag aaatggtgct gcagcataaa gctgtcctgc gattagcggg ccgatgacgc
      661 gcgatagaga ttgtatactt tgggtaccgc ccattacaag accttgctgg ttatctgaga
      721 cagaattgga tagttggcca ttgaatacag gagtaaaaat agaatcaccg aaaccataac
      781 agataatccc aaataaaaac aaaatcggca gtagaagaat tccagataat gtgatgaata
      841 gataggcgag gatttcactg aacatcccta ttcttgtgat ctgctgttct gaaaattttt
      901 tgagcaatcg aggcataatg aacaattgcg agacagtatc caagattcca atcaaagaga
      961 agcttaaacc aaccaaccca gccttccact gaaaggcgtc aatcgaaaat tgagaaaaga
     1021 tagattgaag agagccagct gccaaccaaa cagcaaaacc tgctgtcaat aaaggaataa
     1081 cggatgaaat cttgaataat tgttgtaatt ggtgaaaagg tcttacatgg gagaaactta
     1141 aatctactga acgttttttt attggaaggc tttctagcat aaatgtgtag ccataaacgg
     1201 catttaagaa agtaaagagt gctccaataa atataggaac agaattcccc aactcagcta
     1261 atagaccccc tataatagga cccagcgttg ttcctatacc gactaaagca cccatccatc
     1321 caaaaacttt ggttctttca ttaggttccg tgatgtcggc aaagtaagca tataaggtgg
     1381 agatttctcc tgccgtcaat ccttcaatga tacgaccaag gaacaacatc catatcgaat
     1441 ttcctaaacc aaaaagcaaa tatccgatac ttgatcctaa taaactgata ataaggatcg
     1501 gatgacgccc aaaatgatca cttaagctac cgagaatggg ggcagataag aaggcagcta
     1561 gagcataaac agacatgagc aaagtgatat agaaagcttg ctgatgtatg gagtgagaat
     1621 aaggcagcgt taaaaacgga agtacaggac tgacgatagt aaatcctaat ccagtgaata
     1681 agacagagac gtatccaaaa actttagaat gtttatttgt gaaactgtac atgtaaaaac
     1741 tcctttatgc aataatgtta acttggaaac aaaaatagtg tatagtaatt ttgtttcctt
     1801 gtcaacattc taaggaacag cgaaatctac ttaatttatt tattccgaaa agtgaagata
     1861 cgcatcaaaa acatgaacaa acaaaaatca agtagacgac attgtaaatc tgaccgatca
     1921 gtgaagtaaa tagaaaagaa acctgttctt gcttcccatg ttttttttac gtatactgtg
     1981 attgagcgga ggagaaatca tgttgaattt agaaaattac ttaagcgctg gacaaacagt
     2041 catatctaat cttttactta aaaattatca taggatcggt ctacaatctg aagaattttt
     2101 atttgttcta cagttgcata tggcacagct tgaaggagat actttccctg atttgcagat
     2161 gattgctatg gatatgggaa tcaaacaaga tcagattttt caaatactgg atcgtctcgt
     2221 aacaaatgga tttatcaaga tagaaacgac gattgtcaac ggtaaaaaag cagatcgata
     2281 taatctttac cccatctatg atctattagg tgagtattta aaaacacaag aaaaaaaata
     2341 cgaagaaaaa acacaagaaa aagaaatcca gtcagtgtat caattatttg aacaagaatt
     2401 tggacgcccg ctttcttcga tcgagttcca gcggatcgga caatggctag aagaagacca
     2461 ttatcagccg gaaattttga agctagcact gcgggaagcc gtattaaatc aggcttatag
     2521 ttttaattac gttgaccgca ttttgctatc gtgggaaaga aaaaatctac gtacaaaaca
     2581 acaagtggaa gaagaccaaa aacgaagaaa acagcagctt cttcaaagag aagtagaaca
     2641 gtcagctcaa caagaagaat tgccgaaagt ctcactgaaa aattggttgg aggagtagcg
     2701 gaatatgtta agcaaacaaa aaacaatgga agctctagaa acgatgtatg gaatgtttcc
     2761 cgaagcacat ggagaactca agcacaataa tccatttgag ttattgattg cagtgatctt
     2821 aagtgcccag gcgacagatg tatcagtgaa taaagcaacg ccagatttgt ttgcctcttt
     2881 tccgacaccc gatgcgttag cagaagcttc aatcgatgaa atcattctta aaataaaaac
     2941 gattggtttg tatcgaaata aagcaaaaaa catcaaagcg tgtgcacagc agctgattga
     3001 acgtttcgat gggcaagtgc caacgtcaag agaagaattg atgtctcttc ctggtgtagg
     3061 cagaaagaca gcaaatgtcg tattggggga tgcattcggg ataccagcaa tcgcagtaga
     3121 tacccacgtg gaacgtgtct caaaacgcct gaggatctgc aaactagatg ctacggtcat
     3181 ggaagtagaa gaaacactga tgcggaaagt accacaagaa ttatgggtaa agacacatca
     3241 tacactgatt ttttttggta gatatcattg cacggcaaga aatcccaagt gcgaggtatg
     3301 tcctttgcta tcaatatgtc aagatgggaa aaatcggatg cgtctaaaag aaaaggcgct
     3361 aaaaaagaaa ccacgcctgt agacgtggtt tctttaattg caaataaatg tatgaattat
     3421 cttgttatta tggagaaaag ctgtttcgtt tatctttttt gcatgaaaaa gtaaatgtac
     3481 atactcagta gctaggatgg taacttatta caatttattg cgataaaaat aaaagttgtt
     3541 atttttattg ggaaaatacc cgatgtagaa aataatgcct tccaatatac ctataaaata
     3601 agtccagtat tccaaaggat tatataaata agtgacgtat ctatctaaag gtgtaataaa
     3661 aatgataagt gataataaaa aaataccatt tataactaaa cataaactaa tggatttggg
     3721 cggtttcagg ctcatcagaa aaatatagat tctggtgaac aacaaccata aaaaagtgag
     3781 aatcattgca tgagagcttc tttccataaa ttttccttta agagtagtgc ttaaaagtac
     3841 agaaaaaata ataaatgcaa ggataggagc aattaaagta aatttattta ataataaaca
     3901 aaatttttca gcttttttat tcttggaata acgaggtatt gttttcgata aaaaaagatg
     3961 gtgcagacaa attatgataa ttaagcatac tatcagataa ctcaaaatga agccttcttt
     4021 caaaaaatta ttcaaaacca tatattgtat tttttatttg ataataacaa tgggattatt
     4081 aagaagtggc actaaataaa agactagtgt gtatttagcc gatttaatta taaacaagta
     4141 aatggataaa gtatatgtaa tgataaaaga aaaatggatt ttctaatttt taagctaaat
     4201 gttagatcac acatgtatat gctggatagt cttataaaaa atcatgtaat acagcttggt
     4261 acatgatttt tatttgtagc tgttttttac atagacacaa aaaagaaacc acgcttgtag
     4321 acgtggtttc ttttttacta tctgtttcca gaagctgagg tgctgctgga tggtgtatgg
     4381 tcatttgcag catccgctcc gctagttgct ggctcactgg aagaagcagg aggagcagat
     4441 gaagacggtg tcgagctttc ttcggatgaa gaagaaggaa ccgttgttga agacgctggc
     4501 tcgcttgttt ctgctgtcgt gctttctttt gaggactcag cagttgattc gctttgacta
     4561 gtagagctag agctttgagt cgttgtctct gttgttgagc ttccaggagt ctggacatag
     4621 ctggaagatg gaatagttgt tgatggtgta attgcattcg atctagctgt atattgatct
     4681 ttgtagtaca gttcaccgcc cacacgaatt aatccgcttg gcatctccca gtctgtattt
     4741 gtcacgttag ctgaaacata ctgcataagc tcgcgataaa catcagaggc tacgtgtgac
     4801 gattctgaag tgacaggcgt cattttttta ttgtaacctg tccacacgga aatcgaataa
     4861 tttggcgtat agcccgcaaa taggatatct ggatacaccc cagaagaaat accaagtttt
     4921 gcatactcgt catctgtgta attggatgtt ccggtcttac cggcttgata taacccagcg
     4981 atttgcgcat tcgtaccagt tccttcagtg atcgtatctt ttaaaatgtc tgtgatcata
     5041 taagctgttt ctggagacat ggctgttttt ccatctggct cataagtttc ttctgttccg
     5101 tcttggaaga cgattttatt aacatattga ggtttgtaat aagtccctcc attggcgaaa
     5161 gccgcatagg ctgctgccat ttttaaggaa gaagctccgt attttgtccc atcttgttct
     5221 tccgtattac tagagatcgc attcgattga tggatcgtac tgtattcgat cccaagattt
     5281 tttaagaaag aagccacttt atctgaaccg acttcattga ataatttgac tgctggaaca
     5341 ttacgggata agtaaagtgc ttggcgtaaa gtaatggtgc ccatatattg attatcccag
     5401 tttcctacag gagtcgaagt cccttcatag ttatacggtg cgtcagtaat agtttttcca
     5461 gtagaatatt tcaaatattc aaaagctggt ccgtaatctg tgacaggttt catcgtagaa
     5521 ccaaaatcac gggaagtatt cactgctaag ttgttgccta aagttacgtc ttctgcgatg
     5581 tgacgtccgc caatctgggc ttttactttc ccggtattgg tgtcgataag ggtggaggca
     5641 acttgcatct cgtcgtctgg gtaagagaca tactgatccg tgttgacgat atcatatagt
     5701 ttcttttggg cgtccagatc caaattcgta taaatctcta aaccgtctgt gtagacattc
     5761 ttatctgttt tttcttgtac ttcattgatg acttctttga cataattatc gacgatctta
     5821 gtattgtcat cggattgagt tagttcttgc agaccatccg ttaccggtac attaacagct
     5881 tgatcatatt ctgtttgaga gattttttcg ttttgaagca tcgtatacaa aacagtatct
     5941 cgtcttttct tcgcctgatc tggataaaca taaggatcat aggcggaagg ggcttgaggc
     6001 atcccagcaa gcaatgctgt ttgcggtaaa gaaagttctg ataatttctt accaaagtac
     6061 atctcagaag ctgtctccat cccgtacaag ccgtttgaca tatacacttt atttacgtag
     6121 taggtcaaga tctcttgttt cgattttttt tgttccaatc ttacagccat ccacgcttct
     6181 tgggccttgc gtttcagagt ctgatcctcg gcactggtgg agaagaagga aagtttgatc
     6241 aattgctgtg tcaaagtact tccgccttgc agtccgccag aggtaaagtt agagagggca
     6301 gaaccgatga tccgaatagg gtcaaccccg atgtgtttat aaaaacggcg atcttctacc
     6361 gacacgatcg catcttctaa tgttttcggt aattcattcg cagaaatttt ttcacgcttt
     6421 tctgcgccta aatcttcgaa tagttcgcca tcttgtgtat atagtttgga agatacggta
     6481 gcgtctaatt ttttatccgt caattcgggc gcatcttttg cgtaatacca gaaaagtcct
     6541 acacctgcta aaaagaggat acagaaaaat gagagtattc ctaaaaggat cttgataaat
     6601 aatccttttt tatgtgttcc agaggacttt ccagaacctt tgccagaatt cttcttcaca
     6661 ctctttttag gagtaggctg tttctgtcgt ctagagcttc tagtttgttc atttgccatt
     6721 cttgctttct ccttcaatag ataatgttga taaatagaag tcaaccgcgt ccaaataagg
     6781 aatccgcgga gaaataccag ttttgatctc tattcctagt tcttcgatca aagataaagg
     6841 tagtgatttg cgtccttttt ccttttgggc gtcccagtaa gcaatcaaat gaacactatt
     6901 caaataaaaa cagcgcttca aagacgaaaa ccataacaag acaaagcaga ccccattttg
     6961 ttcgaggcat gctttcatat gttcgatttg atgggcatgg aagtttttaa agggaaaaga
     7021 tgttttgttc ttggtttctt ttgcttcaaa gtccaagtaa aagcctcgat agacgccatt
     7081 atagtctgta gttgaggctt gggtaaagta ggcttccttg atcacagcag cacttctctt
     7141 aggatagtct actttcacga tttggatagg ggtaggcttt ttatggataa ccgccaaccc
     7201 gcgggaaaga taatatttat tactttcatt gattgcttct tcaaagcgca tcccccgatt
     7261 gccgaattca gtgatctgat ttcttttttc ttgaattttt tcgacgggag aggcattctt
     7321 ataataaggt tggccatttg gatagcgcaa taccatcttt aatcacactc ctaggccaca
     7381 ttatagcaaa aaagcggata gaaagaaaag gaatctgaga tggataagtc aaaagtaatc
     7441 tatgtgtctg ggtatcgaag tttcgaactc ggtgttttta aagaaaatga tcctaaaatc
     7501 caagttgtta aaaatgtttt aaaaaaagaa ctccatcagt tagcagaaga agggctggaa
     7561 tgggtacttg tcagtgggaa tttgggcgtc gaactatggg ctgtgcaaat agtagcggaa
     7621 ttgaaagaag aatatccgga actatctctt ggtattttgt atcctttttc tgattttggt
     7681 aataactgga atgaagggaa ccaagaaaaa aaacaattag cagaacaatt agcagattat
     7741 gtcgaagctg ttagccatca accctaccaa tcacctagtc agctaaagaa tcacactcgt
     7801 tttatacttg agcatacagt gggctgtctg ctgatctatg atgaagaatt ccctggaaaa
     7861 acgaagtatt tttttgaaga tgcacagaat taccaagcag atcatcccta cgaaattcgg
     7921 ctgatcagta tggacgatct tcaaaatttt agtgaataat cgatattgtg tttgatttat
     7981 caactttttt cctatacaat gaaaaaggta gaaatgttat tacgtaaatg aaaactagag
     8041 gtgtaaatat ggcgaatttg gtttatagtc ctaaagacat tttacaacaa gaattcaaaa
     8101 caaaaatgcg cggctatgat cccgttgaag ttgatgaatt cttagacaat atcatcaaag
     8161 attatgaaac ttacagcaaa gaactacttg ctttacaaga agaaaacgat cgattgagtg
     8221 caaaagtagc tcaattatct aaaactcaag gagcagctca aacacgcgtg caacaaacag
     8281 aggcaccaaa gagcgcagca gtgaccaatt ttgatatctt aaaacgcttg tcaaatcttg
     8341 aacgtgaagt atttggtaaa aagcttgatc aacaagcaag tgcagtcaaa ccagcacaac
     8401 ctaatccaaa taactacaca aatgcagaca caagcttaga tgataatgaa aaaacacgtc
     8461 aattttaatt tttgattaat gaatttgcgg ttttcgggta atcgcggtct gacttgatca
     8521 ggctgaggaa agtccatgct cgcacaggct gtgatgcctg tagtgttcgt gcttagcgaa
     8581 accataagct aaggtactct ttggagtaac ggcaggaaaa caagctaagg cttcggctat
     8641 gcttaagtat ccttgaaagt gccacagtga cgaagcggct ggggaaaccc atccggtgga
     8701 acgcggtaaa cccctcgagc gagcaaccca aacaatggta ggggcgcttt ttgtctggaa
     8761 gaagaacagg acaaaaaggc agtataactg cagatagatg gttaccgctt tgttttttct
     8821 ccctggaaaa gcaaagtaca gaacatggct tatagaaaac cgcaaacatc agggaattag
     8881 gtcgtgacaa aagtaatgcg ttataagaaa caagaaaaac atttgaaagc tatttttcaa
     8941 tacttcagat gaatcgttct tattacaaaa caaacttttg tatcaccggt tattcggaat
     9001 ttgagtaaaa gtgtggggta ggactgatgt cccacctcct ttttttataa ataaggagat
     9061 tgtgtatgga aaaaaacagg aagttcaacc tcgtcgcaac tgcggcaagc gggctagaag
     9121 cactggttgg taaagaatta agagatcttg gaatcgaatg ccaagttgag aacggacgtg
     9181 cacgttttga aggaacaatg gaaacgatcg ctacagctaa tttatggtta cgtacagcag
     9241 atcgagtaaa aatcgtggtt ggggaattcg atgcgtatac gtttgatgaa ttgtttgaaa
     9301 acgtaaaagc attgccttgg gaagattttc ttccactaga tgcagctttt cctgtagctg
     9361 gaaaatcgat caagtcgaaa ctatatagca cacctgattg ccaagcgatc acaaaaaaag
     9421 caatcgttga acgtctccgt acctattatc accgtccagc ttctgtacca ctgacggaaa
     9481 ctggcgcaca ttttcagttg gaagtagctt tgctgaaaga ccatgtgatg gtaactctgg
     9541 atacgacagg accaagttta ttcaaacgtg gttatcgctt agaaaaaggt ggagcaccat
     9601 tgaaagaaaa catggcagca gcacttatta tgttgacaaa ttggcgaaaa gaccgtccat
     9661 tttatgatcc tgtatgtggt tcaggtacgc tttgtattga agcagcctta ataggccata
     9721 atatcgcacc aggattcaat cgtgagtttg cttgcgaatc ttgggattgg ttcagtcaag
     9781 aaatcatgga aaatgttcga tcagcagccg aagaaaaagc agattatgat attgaattag
     9841 atattactgg ttcagatatc aatggacgga tgattgaaat tgccaaagcc aatgcagaag
     9901 aaatcggatt aggctcttcg attaccttta agcaacaagc agtcaaagac ttcaaaacgg
     9961 ataaagaata cggggtcatc gtggctaatc cgccttacgg agaacgtcta ggagaagaag
    10021 aaactgttcg gaaattatat aaagaaatgg gcgatgtatt ccgtccatta aaaacatgga
    10081 gtaaatatat cttgactagc gacttagcgt ttgaggaatt ttacggacaa aaagcaacca
    10141 aaaaaagaaa attgtacaat ggtgcattgc gtacggatct attccagtat tggggaactc
    10201 gtccgcctag aaaaaaagag aaagacgaat aatcttacta attgattcat tcaattggat
    10261 gtttggagga atagggaatg aaagaaaaag agtttttaca agaagtaaaa gaaatcaatc
    10321 ttctacaaca agctttagga atcctcgatt gggatacaca aacaggtatg cctgaaaaag
    10381 ctagtgcata ccgaagtgaa gtagacagct atctttacag catttatttt tcaaaaaaaa
    10441 tcggtccaaa aatcaaagaa gccattcgct atttttctga acatccggaa gaattgtcgg
    10501 aagttggaac tgccgttttt gccaaagtaa aagaagagta tgatttggaa catcgcgtac
    10561 cggaagatct tatgagaaaa tatacagctg ccgtttcttc agcacacgga caatggcaaa
    10621 aagctagaga aacacaacaa ttttctgatt ttcaacacgc attgaatcaa aatattgaat
    10681 taacaaaaca gttgatacct tactggagaa aagatgaaaa gacgaattat gatgttttgc
    10741 tgaatcaata cgaacccggg atgactgtcg aaatccttga taaggtattt gatcagctta
    10801 aagaaggaat tctttcgatc cgccgtacgc tccaagaaaa agggactgaa cctgaaacag
    10861 actttttaaa tcggagaatg acgaaaaaac aacagaagag atttgtagtg aaagtaatcg
    10921 aacaacttgg ttatgatttt agtcgtggtc gtttagatga cactgtccac ccatttatga
    10981 ctggaattaa tccgaatgat gcacgaatca cgacacgatg gaacgaaaca gatttcaaaa
    11041 tggctgtttt tggagtgatc cacgaggctg gtcatggtat gtatgaacaa gacatcgatg
    11101 ataaatatgc gtatacaccg gtttatgaag gtacatcaat gggtatccat gaatcacaat
    11161 cgttgtttaa cgagatcatt attggaagta gtcgcagctt ctggaaaaag caatatcctt
    11221 tctttcaaga atgtgcagaa ggaacattcg atgatattcc ttttgacaaa ttttatcgtt
    11281 cattgaacca tacaaaatca agtttggttc gtatcgaggc agacagtttg acttaccctc
    11341 tccatatcat cattcgttat gaaatcgaaa aaatgatttt caatgaaggg gtagatgttg
    11401 ctgaactacc tgaaatatgg aatcaaaaat atgaagagta tctgggaata cgaccaacaa
    11461 atgatgtgga aggcatccta caagacgttc attggtcagg tgcaagcttt ggttattttc
    11521 cctcttatgc attagggtac atgtatgcgg cacaattact tcattctttg cagcaagaaa
    11581 tagatgtgga aaatgttcta gcgtcagacg attattctcc aatcaaaaac tggatgtcag
    11641 agcatatcca tcaatatggt gcatctagaa aaccaaatca attaatcatg gatgcaacac
    11701 atgaaccgct taatccgcaa tacctgatcg actatatgaa agacctgtat tttaatgtat
    11761 atcaggtaaa ataaaataca atttacaaag atagctgaaa ttcatctaat ctatagatgt
    11821 tttcagctat ttacttaaga aagaagtgga acgaatggat aaattacaag tgatcgctga
    11881 ttatagtatg gaccaattag cgcatgatca aacaggacat gggagcgatc ataccaaaag
    11941 agttgtcaag ttagctgaaa aaattttgga gacggaaccg caggcagacc gctttgtgac
    12001 gcttgcagca gcttacctac atgatacgat tgatgataaa gtcgttaaaa atgagaacga
    12061 ggcaaagcaa cagcttcgtg tattccttcg ctctttgcca atagtagagg aacagatctc
    12121 gatgattttt tccattatcg aaaatatgtc cttttctaaa aatctctctg aagcggccga
    12181 actatctctg gaaggtaaga tcgttcaaga cgctgatcgt atcgaagcat taggagcaat
    12241 cggcattttg cgtactgctt atttcggcgg tggacatggg cacccgattt ttgatcctga
    12301 actgtatccg caaacattca aggacaaaga aaattaccga aaaggcacga cagtgatcaa
    12361 tcatttttat gaaaaactgt tcttgctgtc tgataaaatg aatactgatt acggatatga
    12421 agaagccaaa cgaagagaaa ccttcatgcg tgaattctta gaagaatttt ttctggaatg
    12481 gtctattgac gatgaaaatt ttactccaga caattggatc aaaaataaca aaaaatgatg
    12541 gaggttgtga cagaagtggt cagctccaag atatttcgga tcattttccg taaaagttac
    12601 ttctggaaca ctgtttacca agaggtcgtg agcctgccgt tcagctccga gtcacaagga
    12661 acaatttcaa aaaatagctt ctcgtgtttg atgaatattg taacttgtga ttcggaattg
    12721 gcaggagaac accgtttatt
//
LOCUS       DACGEU010000078        12739 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.079, whole genome shotgun sequence.
ACCESSION   DACGEU010000078 DACGEU010000000
VERSION     DACGEU010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12739)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12739)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12739
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.079"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(86..265)
                     /gene="rpmF"
                     /locus_tag="IXR40_002145"
     CDS             complement(86..265)
                     /gene="rpmF"
                     /locus_tag="IXR40_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HAQ4361975.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(323..892)
                     /locus_tag="IXR40_002146"
     CDS             complement(323..892)
                     /locus_tag="IXR40_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HAQ4361976.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            1078..1980
                     /locus_tag="IXR40_002147"
     CDS             1078..1980
                     /locus_tag="IXR40_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAQ4361977.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            complement(2015..3799)
                     /gene="pyk"
                     /locus_tag="IXR40_002148"
     CDS             complement(2015..3799)
                     /gene="pyk"
                     /locus_tag="IXR40_002148"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HAQ4361978.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(3873..4835)
                     /gene="pfkA"
                     /locus_tag="IXR40_002149"
     CDS             complement(3873..4835)
                     /gene="pfkA"
                     /locus_tag="IXR40_002149"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HAQ4361979.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(5003..8317)
                     /gene="dnaE"
                     /locus_tag="IXR40_002150"
     CDS             complement(5003..8317)
                     /gene="dnaE"
                     /locus_tag="IXR40_002150"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HAQ4361980.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KGQLIYLLGEDNVVFK"
     gene            8548..8733
                     /locus_tag="IXR40_002151"
     CDS             8548..8733
                     /locus_tag="IXR40_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HAQ4361981.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(8795..9991)
                     /locus_tag="IXR40_002152"
     CDS             complement(8795..9991)
                     /locus_tag="IXR40_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAQ4361982.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(10161..11597)
                     /locus_tag="IXR40_002153"
     CDS             complement(10161..11597)
                     /locus_tag="IXR40_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HAQ4361983.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            11890..12699
                     /locus_tag="IXR40_002154"
     CDS             11890..12699
                     /locus_tag="IXR40_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAQ4361984.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
BASE COUNT         3803 a         2673 c         2250 g         4013 t
ORIGIN      
        1 tattttttat ttaccgacta caaaaaaata aacctcaagg ctccatggtt agccttgagg
       61 ttttacattt tctaattaaa atgtattaag cttcttttga cattacgtcc ttaccatcat
      121 agtaaccaca atttgcacat acgtgatggc tttttttcat ttcaccacag tttggacatt
      181 cgtttaaccc tttgattgtc aatttgtagt gtgtacgacg ttttgctttt ttagcttttg
      241 atgttcttct agctggtact gccattttgc tacacctcct tgtaaagtct tgtatctaaa
      301 ttagacacaa tatattccaa tcttacttgt tatcgtcgtc ttttgattta gaatcaaaaa
      361 gttcagatag ttttgcaaga cgaggatcaa ttttattctc ggcttcttcc atttttctgc
      421 gctggtattc ttcttcggaa acaacttccc aatcattgcc ttttggaagt tctgttgctg
      481 cttcctcttc ttttgtcaat acccgcattg gaatcgccaa taagatgttg tcttcaatcg
      541 actctgctaa attcaataat ggaccttcaa ttagcaaaat ctcatctgca gacatttgtt
      601 catctctact ttggaattgt tcttctgtca tgaatacttc gtctacagaa aaatccatgg
      661 gcagttcaac aggttctagt gaacgtgttg aaggaactgt caaagtcgtc tgcacagtgt
      721 aatgaacgat atagcctttc ttatcaactg agaccaaacc ttcgacttcc actggcgcaa
      781 catcaagtat taaattgtct cgcttcatga gagcggcttt caagtcgagc gtctcatgaa
      841 aagttaacgg tgtctcctgg tattttctca attccaataa agaccatttc atttttcatc
      901 actcctaagc aacaaaagca attatacagg gcaaaaagca tgttgtcaat gaaattttct
      961 tgacaccttg cagttcataa aaaaacagaa aaatctttat tagaaagcct ctgtttgcta
     1021 tcatcctcag aatcatttac aataatcatt attccattaa aggagcggat gatcttcatg
     1081 aacacgaaag atatcgaata ctatgtccaa atcgtcaaac aaaaaaattt tacgaaagtg
     1141 gctaattatt tccgtgtgag ccaacctact attacatatg cattacaacg tcttgaaaaa
     1201 gagtttgaca ccgtacttat tacaagagat cgatcgcatc acgaattaat cgtcacgcct
     1261 tctggaaagc agctgtttct ccatgcacaa accattctcc aagagatttc tactgcaaga
     1321 gctgaaatca ctcagttgca aaagaaaaag cttcgttttg gcatgcctcc tattatcggc
     1381 aatgaatact ttcctaaact gtcaagttac tttatcaagc atgaattgat gaatcaaatt
     1441 gagattaccg atggaggctc tcgggactta tacgggatga tccgacaagg gaggatcgat
     1501 ttagctgtat taggctcaac acagccaatc gtggatcaat atttagaaac agagttactt
     1561 ttggacaaac gtttcatgat cgtcgtgcca cctacacatc ctctttccaa gcaggatact
     1621 gtctctttca aagatatagc agatgaacag tttgtactat tgaacgaaca ttatgtccac
     1681 cccgcagcat tcactaagct ttctaaacaa acacatactc atccaaaagt tgtttatcaa
     1741 agcaatgact tgacgatttt aaagagtatg gtccgagaaa atgtgggtat cggttttttg
     1801 gcagagattg ctgtccatcc tgaagatcat ttagtttgcc tccctctttc agatgaagtt
     1861 cagcctcgct tcttgatttc attggcaaaa cgaacacagc agatcgtcac gcctcttcaa
     1921 gaacaagtag tccaagttat ccatgaattc gttacagcac aaaaaaacag ctcttcgtaa
     1981 aagaagagct gtttttattt tttattaagc taaattagat agctgttgtt tcgccacggt
     2041 aaacgatgcc gcgacgtgaa tcaacggtaa tcaattcacc ttctgtaatt gttgttgttg
     2101 cgcctttagc accaacgatt acaggaatat cttgtgcaat tcctacaact gcagcgtgag
     2161 aagtcaatcc gccttcttca acgataacag cagctgcttt ttcgattgca ggcatatatt
     2221 ctttgtcagt tgatggtaca actagaacca ttccgtcttt tgcttttttt acagcttctt
     2281 cagcagatga agcaataact gcatttgcaa cgacagattt ttgtccaacg ccttgagctt
     2341 ctaataattt agaaccaatc atttgaattt tcatcacgtt agttgttccg cgttcaccaa
     2401 ctggtacacc agcagtgatc aagattaaat cgccttctga tgcgaaacct aattcaacag
     2461 cttttttagc tgctagttca aacatttcat cagttgttga tggtttttca gcaactgttg
     2521 ggtaaacgcc ccagtttaac atcaaaccac gttttgtgcg ttcgtcaaaa gtaacagcca
     2581 agatatctgc atctggacga tattttgaaa tcatttttgc agtgtatcct gattcagttg
     2641 cagcaacgat tgttttcacg cctagatttt ttgcagcacg agctacagat aaaccgattg
     2701 tttcagttac atctgtttta tcgaattcgt tcaattggaa tgtacctaat tctgataatg
     2761 cattttcagc ttcttggtcg atacgtgcca ttgttgaaac agcttcaact gggtagtccc
     2821 cgtttgcaga ttcaccagat agcattgttg catctgtgcc atcaaataca gcgttagcaa
     2881 cgtcagaagc ttccgcacgt gttggacgtg ggttttcttg cattgattct aacatttgtg
     2941 tagcagtgat aactgggata ccagcagcat tacatttttt gataatgcgt ttttgaacca
     3001 ttggtactag ttcagctggg atttcaacac ccatatctcc gcgggcaatc ataacaccgt
     3061 cagaaacttt gatgatttcg tcaatgttgt cgataccttc ttgagattcg attttaggga
     3121 agatttgaac atgagtcatg tctttttctt ctaagatttc gcggatatct agaacgtctt
     3181 gtgctttacg tacaaaactt gcagcgataa agtcgatatc gttgtctaaa ccaaaacgaa
     3241 tatcgtcagc atcttttgga gtaatacctg gcaaactaat agaaacgcct ggtgcattta
     3301 cccctttacg tgatcctagc atacctgcat ttttaacttc tacgactaat tcacggtttg
     3361 cttcgtcttt ttcaatgatt tgcatatcga tcaaaccatc atcaaataaa atgtgtccgc
     3421 caacgtgaac atcgtcaaat aatcctgggt aagtaaccgc gattttttct tttgaaccta
     3481 catgttcagg atccatagag atgcgtgttt gatctcctac ttcaaatttg atgtatcctg
     3541 cacgaccaaa atcagcttct gttgtgcctt gaacagttgt acggatttca gctccttttg
     3601 tatctaaaag aataccgaca tcttttcctg tctttttaac tgcttcacgg accatagtca
     3661 tacgtgataa ttgttcttca tggtcaccat gagaaaaatt aaagcggaag acatttgccc
     3721 cagattcaat caattgagaa ataatttcta ctgagttact tgctggtcct aatgtactaa
     3781 cgattttggt ttttttcatt taaaaaactc tcccattcaa ttttgtttat ttaaagctgt
     3841 acacagctta aatagcttgg tttctttcac tcttaaaatg aaagtgaatt atttagatca
     3901 tatagtgata agtctggttt atgtttgttg ttttcaagtg tatcaatgat gtcagacgca
     3961 acgatttcgt tgtcatggat accgacacat aatccacctt ttccttcttg aagcaattcg
     4021 acagcgtaag caccgaattt acttgccaac acgcggtcgc gtgcgcttgg tgctccacca
     4081 cggacaacgt gtcccaagat agatacacgt gtatgatagt caccaaattc tgaaagtttc
     4141 tcagcgaatt catttccgcc cattacacct tcagccaaga tgatcaagca atgtttcttc
     4201 ccgcgatcgc ggccttcttg gattttttta gcaactgaag ccatatcaaa atcatgttct
     4261 gggatgatga tttcatccgc tccgccagcc acacctgacc ataaagcgat gtctcctgca
     4321 ttgcgtccca ttacttcgat aacgaatgta cgaacatgag aagtcgctgt gtcacgaata
     4381 cggtcaattg attctagtac tgtattgatt gctgtatcaa aaccgattgt gaaatcagtc
     4441 ccaggaatat cattatcgat tgttccagga atacctactg ctgggaaacc gcgttttgtc
     4501 aaagccattg cgccatgata agagccgtct cctccgataa ccactagacc ttcgattccg
     4561 aattttttca attgttcgat tccttttaat tgaccttctt cagttgcaaa ttctggataa
     4621 cgtgcagaat acaagaatgt accaccacgt tggatcttgt cacctacatc tgccacatca
     4681 agacgacgaa tatctccagc aactaaaccg gcaaaaccat aattgatccc gtatacttcc
     4741 agtccttcgt aaataccttt acgaacaacg gcacgaacag ctgcattcat tccaggtgcg
     4801 tctccgccac tggtcaaaat tccgatgcgt ttcataataa acattcacct cattaaaata
     4861 ctttatccta agtatgactt aggtttacaa ccatttttgc gttaaccacg actaacattc
     4921 taacattatt tttctcactt gtcttgattt acggataaaa aaatgaaaaa aaatgaaagc
     4981 aagtagtatt ttttaccgta agttatttga aaaccacatt atcttcgcca agcagataaa
     5041 taagttgccc ctttatactc ttgctgtcat ccacccaata agcatctgac agaactactt
     5101 ttcgttgcgt tttttcgtga tacataacta ctggtatata tcctgggtgt ttctgaaaaa
     5161 tcacttgtaa ttgtttcatt atctcgggat cttcccgttc ttctgtaata cgcaaatagc
     5221 aagtttgtga aggatactgg gcttctaact ggttaggatc agcaaagctt tctccaatta
     5281 gttgcagttc ctgattatat ttgctgattt cgctccgccc ttgaacaaag atcactcgat
     5341 caacggcaaa caaattacga tatttacgat aaagagttgg aaaaactgtg acagaaattt
     5401 ctccactact gtcggttcct tcaacaaagg ccatcagttc tccttttttt gtccgaattt
     5461 ctctaacttc cttgatcatc actaataaat tgactggttg attagggacg atatctgtaa
     5521 tcagctgaac ttgtttagct aaacgaagac gatcaaaccc ttctgcagga tgacctgaca
     5581 aataaatacc taagtactcc tcttccagct tcaagcgttc ttctagtgta tagtcagcga
     5641 cttcttcttc ttttaatgcc atgattccca gcaagtcaag acttccacca ctgtaaacga
     5701 tattttggat ttttccttcg agatcaagca tcaattgttt cctgttagga gataattcat
     5761 caaaaactcc tactgctgtc agtgattgca gtaactctaa tttcagccaa cgcttatcga
     5821 tccgtatgag gaattgatcc actgactgga acgggccatt ttgttttctt tcgtttaata
     5881 tatcttctac aaaatcacgc cgaatacctt ttatcgctgt cagtccgaat ctgatttctt
     5941 ccttattgac caactcaaaa ctggaattac tttgattaat ggacggcgag gaaagtttga
     6001 gtttattttt acgtgcttct gcaatatatt ctttcaattt tgatgtgtta tgccgaacag
     6061 aattcatcag gctggtaaag aaagcacctg gatgatgggc ttttagatac gccatttgga
     6121 atcccacgaa tgaataagca aatgcatgtg accgattgaa tccatagttt gcaaattttt
     6181 cgatatattc atatacggtc gctgctgttt tttccgaata tccctgttgt aatgctcctg
     6241 atacaaaatg cgacttttct tcatctaata cgtctttttt ctttttactc actgcccgtc
     6301 gcagaatatc tgactgccct aatgtaaatc cagccatagt cgaggcgatc tgcatgattt
     6361 gttcctgata gacgatcact ccatatgtgt ttttcaaaat cgggatcagt gaatcatctg
     6421 ggtagcgaat ggcttctttt cctttcttcc tggcaatgaa ggtatctata ttttgcatag
     6481 ggcctggtcg atacaatgca ttgactgcgg caatatcttc gatgttttct ggatctaatc
     6541 ttcgtaaaac gttccggata ccagcagatt caaattgaaa tactcctgag gtttcgcctc
     6601 gttgaaacaa gagcagcgtt tttgcatcat ttagcgggat ctcttttaat cggatctcat
     6661 acccttctac tcgcttaaca gctttcaaag taaaatcaat aatcgataag ttgcgtagtc
     6721 ctaaaaagtc cattttcaaa agaccgattg cttctacctc attcatcgta tactgggtca
     6781 gaaaagcttc atcagaaccg cgttggagcg gaactagttc aagtagattc ttatcgctga
     6841 taactacacc tgctgcgtga gtcgaaacat gtcttggcaa tccttctaaa atcactgcag
     6901 ttttgaataa aagttggttt ttttcgcttg cctgaactaa ttctactaat tgatgcgaag
     6961 ttttataagc ttgggtcaat gtgattttca attgattggg tattgctttt gaccagcggt
     7021 ttgcttcact ttgcgataaa ccaaacactc tagctgcatc tctaagaacc atttttgctg
     7081 ccattgtgcc aaatgttgcg atttgtgcca tatgatattg tccatacttt tctcgaacat
     7141 aattcaatac ttcttcacgt cgattgtcag gaatatccaa atcgatatct ggcatcgtaa
     7201 agcgttcggg gtttaaaaag cgttcgaaca gcaaatcata ttctaatgga tccacatctg
     7261 tgatttctaa cacataggct actaatgaac ccgcagcaga accacgacct gcaccggtaa
     7321 cgattttgtt tctatgagca aaagccatta catcccatac gatcaagaaa taatcatcga
     7381 atcccatttg atggatgaca gataactcgt agtccaaacg ttcttggtat tcctttgtat
     7441 agtcagtgat tcggcgttcc acttgcgaat agcataactc tcttaaatat tctccagctt
     7501 gttttccatt aggaactgga taatgcggaa gtaatttctg atggaactgg aattcaaatg
     7561 aaatcgattc agctaaacgc tgggcgccta ttacagcttg ggaaagaccc gctttttcga
     7621 atcgtttgat catttcttgt tctgaaagaa gatagacatt tgctgttagt ggtaaagatg
     7681 cagataaatt ttctaaaggt atttggcttc cctctttgat atgtttcatc acttcaagtg
     7741 caaaaagttc ttcttgttgt aaactagcga tgggatgtaa tgcacaaagc gaataatttt
     7801 cttttatcac atactgatac cattcaggca attgatcagg cgtgttttct gtcaagccga
     7861 tataaaaatt tctagtaaaa acattttcaa gtaaaaactg ccaatgaccg aaaaagttat
     7921 cctctttatt gaaagcctca gaaacagaat gatttgccgg aacaacaaac gctagatggt
     7981 cggtttctgt catttctgca agttccaatt tttcttggat catttttcgg ctggaaagtt
     8041 tcatcagctg ctgataacct atttcatctt ttgcgtacgc aagcaagcca taattttttt
     8101 cttcataagt ataactaaga tgtaatccaa tgattggctg tactccttct tctacacaaa
     8161 tacgatagaa ttcaggtgca ccgtataaga catctttatc cgttatggct aatgaagtgt
     8221 agccttgttt ttttgcttct tgtacatatt ctcgaatacg tatcgtactt tgtaaaagag
     8281 aataagaagt aattgtataa agttgtggga aaaacatctt gcattccgcc ttttttttcg
     8341 ttaaaattca ctagcgttaa aaggtttgat ccttttactt tcattaagat agcaggcgct
     8401 gaagttgatt attccacttc atttgcttgc ttgtaatctg taggaatgag ttctttcgca
     8461 agaactcaaa ttttattgag atttggtctc gtttctttac attcaaagaa aatctggtaa
     8521 aattaagata gaaaagaggt gttctttatg cgatatatcg ttacattatt ctgggctgtc
     8581 gttctaggtc aagtagtcgg ttatattggt gctgcattaa caagcggaac atatgatttt
     8641 actttgacaa caatcatttc attcattgcg ggtgtcatta tccttttgat tggtgcagtt
     8701 gcgccaagaa aagaaacctc tgcccattcg taaaaaaaca gccaagagct tgagatttct
     8761 caagctcttt tttattttct actcctcacc accattataa tctgctgcga agaactttac
     8821 gaaagttgaa taaagaaaga agaatatttg acagaacaaa caaacttgtc acaataaaaa
     8881 cagcactgta attataagca tgcgcgactg tcgatcctag catgggacct aaaacttgtc
     8941 caaagttgct aaacatctga ttgtagctat agattcggct gactccttct tgaggcgtaa
     9001 tcttactgat cagtgtattg acagaaggca tcaaagcgcc agttgaaaag cctaaaataa
     9061 agcgaagtat acctaattgg agcggtgtag tgacgaatgc cataggtaaa taacagcaaa
     9121 atgataaaat gagtcctcca attagaactt tttgattccc aatcttatcc cctagttttc
     9181 ctagtttcgg tgaagaaaag acagcggaaa caccagctat cgaaacaatc aagccgctga
     9241 caaaaaggat attttctgta cttccgctca attcacgaat atataaggtc aaaatagggc
     9301 tgatcgtagt gattcctatc tgtaaaatca aggtcgtaat gaagagaccg atcaaaatag
     9361 agagatgatc catttttgaa aaaatttctt tggtgcttat cagatctttt ttctcgattg
     9421 gatggaaatc ttctttgact aagaaaatgg tcaataccgt tgtgatcatc aacaaagccc
     9481 ctgtgatcaa gaatacattt tccataccaa accactgagc cagtgcaccg cccattgaag
     9541 gtccgatcag atttccagca atcgctccgg tagacaatgt tcctaacgcc catccgctct
     9601 tttctctagg tgcctgtgaa gcaatcatcg ctgtggcatt tggaatatat ccagacaaaa
     9661 tcccattcca aaaccgcatg atcaaaagcc aatacgcgtt tggtacaaaa gccaaagatc
     9721 ccattgttaa tgtcatccct gctgctgcac ggatcatcat gagttttcgg ccttttcgat
     9781 cagctagatt tccccagatt ggtgcaacca cggcagatgc aaaagcagtc acagagattg
     9841 ctagtcccga aaacaattcg atttgatctt ttggtgttcc tagttgctca acataaactg
     9901 gtatgaatgg cataactaaa ctaatacttg caccagtgaa aaaacagcca atccacgcaa
     9961 tcactaaatt ttttctccaa ttaatctcca tctatcatcc ctctttcgtc tcttttatca
    10021 tacctatttt cgaataaaca agcaacgatc tcgccagtaa aaagagaaaa atcccgcaaa
    10081 ggtcatttta tatgtaacgt tctttttatg taaaacaaaa agagatcaga acaaatactg
    10141 ttccaatccc ttctctttag ttaaattgtt gctagaatga tgaagttgat aatgaataaa
    10201 atatcaacga tccacaaagc aacagaaact tgattgtatt ttcctttgat tactttcaca
    10261 attgtataga aaataaatcc tgctgcaatc ccataggaaa tgctatagca caatcccata
    10321 aagatcgatg caaagaaggc cggtaaagct tcttccatat ctagccattt gatgtctgca
    10381 aaagaagcca tcatcattac tccaactaaa atcaatgctg gcgcagttgc ttgatttggt
    10441 acaatggcga tcagtggaga gaataaacta cttaatgcga atagcactgc cactactact
    10501 gaagtcaaac cagtacgtcc accggccccg atcccagctg cagattcgac ataagttgtt
    10561 gtattcgatg taccaaagat agcccccaca gaagtagcga tcgcatcggc aaatagtgct
    10621 ttatccattt ttgttttgaa cccacgacca tcttccaacg cgatctcgtc ttcttttgag
    10681 aaaatacctg tgcggcgtcc tgtaccgata aatgttccga tcgtatcgaa agtatcagat
    10741 aaactgaatg cgatgatcgt catcaatact tgaggaatct tggaagaatc actgaataaa
    10801 gattgcatgc cttcagaacc aaatgctgca ccgaaagttg ttcctaattc tttaaatgaa
    10861 ttacctaacg aattcgtttg ccaatcaatg gaacttaaat caacaacacc cataaaaata
    10921 ccaaggactg tggtcgctac gataccgata agaatagccc cacggacatt ttttacaact
    10981 aaaatggctg tcagtaccaa accaatcaca gccaataaga taggagcgtt gtcaaagttg
    11041 gctaacgcag ggacgattcc accatttatc gtaacatttg tcgcttttcc gccttcaacg
    11101 acagagctcg aaatagctga ctggtctgct gaaaaagata agaatcctgc atttttgatt
    11161 ccgacatacg caacgaaaat accgatcccg ccaccaatcg catgttgaag actttcggga
    11221 atcgcccgaa taatcatttt tcgaatattt gtgacagtaa taaaaatatt gattaatccg
    11281 caaataaaca ccattgccaa ggcttgttgc caagaataac caagcccaaa aacgaccgta
    11341 aaagtgaaaa atgcgttcaa tcccatacca ggtgcctgag catatggtac atttgcgaac
    11401 aatcccatta ccagcgtacc aataatcgat gcaatgattg tcgctagaaa tactgcttgg
    11461 aagggcatac ctgatgctga caaaatcgtc ggatttacga ataagatata actcatggca
    11521 aagaatgtcg ttactcccgc cattatttca gttgatacat ttgtattgtt tttctttaaa
    11581 ccgaaaaact tttccataaa aagttccact ccctgaattt ttttctgatg gaaaactata
    11641 ataataaaaa ataagtaaaa tagggcaaat ccatcgaaca atttcaaatt atatagacgt
    11701 ttcattcgct tttcaacgtt tttttaacaa aaaaagcgaa aataatactt aacgttcgtg
    11761 tttagcttat gtttagctat ttatatagcc ataactgtag tttttgttag gaatagctga
    11821 ttgctcttgt taattaccta aaatatgcta gactaaaaca aatgctagtt gaggaaggaa
    11881 ggacccttat tgaataaaaa attaattgcc atcgatctgg acggaactac cctcaatcaa
    11941 gattcgatga ttacatctaa aacaaaagag actctaaaaa aagcaatcaa tgccggtcat
    12001 catgtcagta ttgctacagg acgcccattc cgaatgagcc atcagtttta ccaacaatta
    12061 gaattaacaa caccgatggt taattttaac ggcgcattag tacacatccc taatcagcac
    12121 tgggatggtg aaagagaaac gttgatcaat cgtgaaatcg cttttgaaat cttatcgcaa
    12181 aaaaagcagc taaatttaga ttttatcgct gctgaaaatc gtgatacttt ttttattgac
    12241 agttttgatt tctttgatga aaaaattttt gcttcttctc gtccaggaga gaagaatttg
    12301 ctttctccta aaaatttgac gacaaatcct acatctttgc ttgtccgaac agacaaacgt
    12361 tttgcaggag ctgtatctgc tgaattaaca cgtcaatttg gcagttatgt cgatgttcgg
    12421 acatggggtg gacctactgc catcttagag attgtttcaa aaggaatcca aaaagcaaaa
    12481 ggcgtgcaag agattgctaa ctacctgtct atcgatcaaa aagacgtcat tgcctttggt
    12541 gacgagcata atgatttgga attgttggat tatgcaggtt ggggagtagc tatggctaac
    12601 ggtactgacc aactcaaagg cattgcaaat gatgtcactc ctttgagcaa tcaggaagac
    12661 ggtttagctg tttatctgga aaaactactt aaactataat agagaattag attccacaaa
    12721 aaagaggttg tgacaattt
//
LOCUS       DACGEU010000079        12675 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.080, whole genome shotgun sequence.
ACCESSION   DACGEU010000079 DACGEU010000000
VERSION     DACGEU010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12675)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12675)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12675
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.080"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            11..310
                     /locus_tag="IXR40_002155"
     CDS             11..310
                     /locus_tag="IXR40_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAQ4361985.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            383..1744
                     /locus_tag="IXR40_002156"
     CDS             383..1744
                     /locus_tag="IXR40_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HAQ4361986.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1766..2026
                     /locus_tag="IXR40_002157"
     CDS             1766..2026
                     /locus_tag="IXR40_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361987.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2040..2792
                     /locus_tag="IXR40_002158"
     CDS             2040..2792
                     /locus_tag="IXR40_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase"
                     /protein_id="HAQ4361988.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2886..3491)
                     /locus_tag="IXR40_002159"
     CDS             complement(2886..3491)
                     /locus_tag="IXR40_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAQ4361989.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIKQAREWTDHLLTK"
     gene            complement(3544..4518)
                     /locus_tag="IXR40_002160"
     CDS             complement(3544..4518)
                     /locus_tag="IXR40_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HAQ4361990.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DGPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4896..5675)
                     /locus_tag="IXR40_002161"
     CDS             complement(4896..5675)
                     /locus_tag="IXR40_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAQ4361991.1"
                     /translation="MLLRVVGSIIFRYTLEEVNNVPKYEEIANILRERIRSKEYPLDS
                     FLPNQVDLVKEFGASRMTIKKAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEY
                     EGLSLQMKRRHRSLKSQIIHFDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVL
                     EHTFMPVHLVPGLKKEHLLASIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAE
                     NDPVLEVQQVVYLKDGQPIEYSSSRNRFDVRNYSVLDVRST"
     gene            complement(5742..7013)
                     /gene="celB"
                     /locus_tag="IXR40_002162"
     CDS             complement(5742..7013)
                     /gene="celB"
                     /locus_tag="IXR40_002162"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HAQ4361992.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7166..8563
                     /locus_tag="IXR40_002163"
     CDS             7166..8563
                     /locus_tag="IXR40_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAQ4361993.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWDHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSHLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKVIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGIIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8644..9084
                     /locus_tag="IXR40_002164"
     CDS             8644..9084
                     /locus_tag="IXR40_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAQ4361994.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9232..9558
                     /locus_tag="IXR40_002165"
     CDS             9232..9558
                     /locus_tag="IXR40_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAQ4361995.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9559..10308
                     /locus_tag="IXR40_002166"
     CDS             9559..10308
                     /locus_tag="IXR40_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361996.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10388..10843)
                     /locus_tag="IXR40_002167"
     CDS             complement(10388..10843)
                     /locus_tag="IXR40_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HAQ4361997.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNLENSTDLDDEFLNYYI"
     gene            complement(11270..11545)
                     /locus_tag="IXR40_002168"
     CDS             complement(11270..11545)
                     /locus_tag="IXR40_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4361998.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
     gene            11839..12654
                     /gene="thiD"
                     /locus_tag="IXR40_002169"
     CDS             11839..12654
                     /gene="thiD"
                     /locus_tag="IXR40_002169"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HAQ4361999.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKNAQQETVNDYVLFESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
BASE COUNT         4056 a         2175 c         2591 g         3853 t
ORIGIN      
        1 ggaagaaaaa atgaaaaatc ggttaattgt cgcatgtgga agtggagtag caacgagtca
       61 gacaatcgct agtaagatcc aaagtatgtt agaagatgac ggcatcgcat ttcctgtaga
      121 agcagttgat tacaaatcga ttcaaaatga gcttctaact gctggaatct atgtgtatgt
      181 cgcacaacct gatgaggaag tacttgaaca agcaaaagat ttgggtattg aagtatttcc
      241 aggaattcca tttttaactg gaatgggtgt agaacctatt tatgacagta tcaaagagtt
      301 agtacagtaa aggaggattg ttggataaaa aagttggttc atagttttat ttactatatt
      361 tagaaagaaa gaaggtttat ttatggaagt tttccaaacc attatcaatt atgttttgaa
      421 cttaggatca gccatttttg ttcccctgat tattttgata cttggattgt tggcagggat
      481 gaaattaaaa aaagcattca tgtctgcttt gactttaggg attgctttta gcggaatgtc
      541 tatggtcatt ggctatatgt ctaacgcagt aagtccagca tcagaagcat tggctaaaaa
      601 tacgggaatc agtttgcctg cacttgatct tgggtggaca ggtgcagcaa gcatcacatg
      661 gtcgtggagt tatgctttta tattttttgc agtaacgatt ggggtcaatt ttgtactgtt
      721 actttttaat tggacgaaga cgttaaatgt tgatatgtgg aatgtttggg ggaaagcttt
      781 aactgcttat ttagtttatt atgtttccgg tagtttggct gcaggctttc ttactgcaat
      841 ggtccaagtt atattggaat taaagcttgg tgatatgttt caaaaacata tacaagatct
      901 cacagggatt ccattagtaa cagtgactca ttttatgaca tctgccgctg tcttgttgct
      961 gcctttcaat atgatcatgg ataaaattcc tgctttaaat aaacgagcgg atacgaatgc
     1021 attgaagaag aaaattggga tcttctctga aaactctgta atgggattca ttattggatt
     1081 ggggcttggc tttgctgctg cgtatggcgt ttcaggttct cttaatctag cgatccaaac
     1141 agctacagca ttaagtttgt ttcctatgat ctctaaaatg ttcatgcaat ctttgtctcc
     1201 tctagcagac gctatgtcag aatttatgaa aaagcggttt aaggatcgtg aagtatatat
     1261 cggattggac tggccgatat tagctggtcg ttcagaaatt tgggttactg ctattttact
     1321 tgttcctgtg tttattggtt atgccattat tttgccagga aaccaagtat tgccattagc
     1381 agggattatc aactattcga ttgcggtcgg cggattactt ttaacaggag gaaacttggc
     1441 tcgtatgctg atcttgggaa tcatcactat gcctatttat ttgtacgggg ccacttacct
     1501 tgcgccaata ctcagtgatt tagcagaaaa aagcggagca gtcgagggaa tcaagaaagg
     1561 acagttgatc acatggtcat ccatagaagg gccggagttc agggttttat ttgcggaggc
     1621 atttaatagg aatattctcg ctattgtagg atgcgtgatt tttctaggac tgtttgttct
     1681 actttataaa tatatgataa aagcgaaagt accgagtgaa cgttatgctg aactacaaaa
     1741 atagcattga aatggtggga aagtaatgaa aagagaagag acagataaaa taaaatggac
     1801 agtcgctctt tgtggtacac ttctgctatt tctatatgga ctctttactc agaatatcat
     1861 catcaatcta ttggtcattt ttttcgcact agtgatctat aaatatggaa atcacgtttt
     1921 attcagagag tacgatgaaa aaagaaaacg gaaaatagaa gaatcaatga aaataaaaga
     1981 agctaccaaa gaaatattga gagaaaaaag ttttataaaa agataatgga ggggtcatta
     2041 tgtcagatgg acgtatgtta tttgagagag aacgacagga catggcacgt atcgtaagag
     2101 tgattttcga aaggaaaaac acaaatgtcg caggagggaa tttttccttt aaaaccactg
     2161 atgatcaagg gaaagactac atcatcatga cgccgaccat gatgtcagaa gcctatctag
     2221 gagagatttc tcctgcacag gttctagtag tagaaccaag aacgcgtaga atcgttgacg
     2281 gagtcggtca tttaactcgt gaaatcaata tgcatgaagc gatgtatgag actaatccag
     2341 ctatcaaagc tgtcctacat gctcatgcgc ctaatgcaat gttctgggcg actactgggt
     2401 tgcctatgcc taatttgaca gaagccacag ctaaagtaaa agagattcct gtcatggact
     2461 ttgagcctaa ttgctctgaa gaacttgctg aattgacaag cgactatgta aaaaaacagc
     2521 atctcgaatt accgcatatg ttgctgctca actctcatgg cgtattgatc aacacaggtg
     2581 gagaatcagg aatcgaagct atccataaag cactgcaaat ccttgataca gttgaatgga
     2641 atgcagaaat tgcctacaag cagacgattt ttcaagcatt agggattact gacggttttt
     2701 attcaaaagg tgagaaaatc gggggattgg aagagttgaa acataaaacg gctatttata
     2761 ataaatctgt tattgcagct ggtggagact aacctatctg acacaaaaaa ctacgacttt
     2821 cacaaaatct gatccagatc gatatctgct tcaggttgta ttatgtaagt cgtagttctt
     2881 ttcttttatt tagttaagag gtggtctgtc cattccctcg cttgcttgat ttcgtccatc
     2941 gtcaactgat gacctgttac agttagctga atagtcacat ttgcttggcg tgtttcgaat
     3001 tgatcggcca attctttaaa ggaagcaggg gaaacgattg gatcgttatc accataagaa
     3061 atccagacgg ttttatcctc taatgtggaa cggctttgat gaacacctag agacatcgga
     3121 tggaaaaaca accctttatt tagctcggtc tcacgctcca ataataaatg agcagcgatg
     3181 tttgcgccat ttgaatagcc gacaagcagc cagtcactta acggtatcag ttctttttcg
     3241 ctgatttctt tgattttttc atggagttta tctgtttctt tttccaaact gtccaggtcg
     3301 aattgattca atccattacg cttgaaaaaa cgattcatcc catcttcttg gaccgtgcca
     3361 cgaaaagaaa gcaatgtact gtttggtgca agaaagtgag cgatatccag taaagaatgt
     3421 tcatcgccac ctgtgccatg aagtaagatc aaatgcttgc cacttgttcc tttttcaaaa
     3481 atgtaggtca ttttgttccc tcttttctgt ttctatagat gcaaatgaag tagcatgaag
     3541 agattattca cgttttttat ttgcatcact tgtatcgaaa ggacggacat aagcttcaat
     3601 ggcttcacga cgttcttcta agaatggagg aagagatagt ttttctcctg ctgattctgc
     3661 tggttcatct tcaaggaatc caggaccatc agttgctaat tcaaacagta cgtgatgagc
     3721 ggctaggaag tactcagatt ggaaatagaa acgatcgacg aaaccagaat ttggcaattc
     3781 aatcttattg attacttgaa tccagtattc caatgcttct ttgtctgcta cacgcaatgc
     3841 taagtgatgg atatttccaa atccttcgat tgcttttggc aagtctgtcc gatgttcaat
     3901 aatgatgctt gcaccatttc ccccttcacc gatttcaaat aagtagaaat ctcctgaatg
     3961 gtctgtttct ttgaatccta agattttttc aagaatcaag cggatatgct ctaattgact
     4021 gacacggaca aagacaggtc caagtcctgt gatcgcaaac tctgtcggta cattgctgtt
     4081 tttccaagga atgccagctg ctacaccttg attgttttcg tcagagatca attgataata
     4141 ctgattatcg aaatcttcaa attcgatata ttttttgccg aaacgttcat tgattgctga
     4201 atgagtaacg tcatattttt caaaacgttc caaccaaaag tctaatgctg cgtcacttgg
     4261 cacacggaaa gaagcacgag agatcgtatc tgttcctttt tttccttttg gctgatttgg
     4321 aaaatcaaag aaagtcatat ctgttcctgg cgcaccagta tcgtctgtaa agtaaagatg
     4381 gtaagtttcg atgtcatctt ggttaactgt ttttttgatt aagcgcattc ctaaaatatc
     4441 tgtaaaaaag cggtagattt ttgtagcgct agatgtcatt gctgtgacgt ggtgaattcc
     4501 tctgatttgt gtatccatga taaatttcct cctgttaact tacaaaaagt aagtagttga
     4561 tttagacata gtatagaggg tgcatctcta ttttgcaatt aatttgtctt ctaaagtatc
     4621 aggaaggaat caagaatgga aaagaggagg gacggatcaa taaaataaaa agacttacga
     4681 ctagctgtat cgatttcaaa aaaactagct ttaaaaagct aactttagaa tcattacggg
     4741 tggtcataag tctttttatg ctgagttatt ttttcatttt tgagctaatg cttaggatag
     4801 aatagaatgt tgatttcacg atctcttctt gttacttgaa actgcttacc actgtcacga
     4861 tctcttggta aacggctttt tcacaacctc tttggttaag ttgaacgcac atccagcaca
     4921 gaatagttcc gaacatcaaa tcggtttcgg ctggaagaat attcaatcgg ctgtccatct
     4981 ttgagataga cgacttgctg aacttccagt acaggatcgt tttctgcaca gttcaaatat
     5041 tgctgatcat attcatcact tttatctgca gaaatagcac gataagcccc tgcaaaatgg
     5101 acattcaatt cttgatgaag atgatcatag atagaggcta acaaatgttc tttttttaaa
     5161 cccggcacaa gatggactgg cataaaggta tgctctaaaa catatggctc gccatctaag
     5221 atccttaacc ggtgaatatt gtagacaggt tgctcggcat cgatcatcaa tcgttcttgg
     5281 atatattgat tagggaattc aacatcaaaa tgaatgattt gactcttcaa agaacgatgt
     5341 ctgcgtttca tttggagact caaaccttca tactcgttag cgggcgatgt gtctttttgc
     5401 ataaatggat gattcaagat tttcgttcct gatcctcgct gcgaatagac aagtccttcc
     5461 attgctaaga tattgatggc ttttttgatt gtcatccggc tcgcaccaaa ttcttttacc
     5521 aagtcgactt gattaggcaa aaaactatcg agaggatact cttttgaacg gatacgttct
     5581 cttaaaatat ttgcgatttc ttcgtatttt ggcacgttat tcacctcttc tagagtataa
     5641 cgaaagatta tgcttccgac aactcgaagt agcatctgga acattgttta ttcgaaaaaa
     5701 gaggtcatga caagtttttg tcacaacccc ttaatgatct attaagcaat atctaaatct
     5761 ggttgtttat ctagtacttt caggaatggg taccagataa aggcaacgat gacaaagtcg
     5821 atgacttgca gcataccacc aagccatgaa tttgttgcta agacaccgct tgcaatgatt
     5881 ggcacagtcc atggaacaga gacgccagtt ggtgcaggga caagtccagc agccattacc
     5941 aaataattga acgtcgttac gattagaggt gccacaaccc aaggaataag gattgttgca
     6001 ttcaatacga tcggtagacc gaagatcgct ggttcattta cattgaaaat accaggtgct
     6061 aaagctaatc gtccaacatc acgatactgt ttctttttaa gaacaaaggc catcaataaa
     6121 acgacagcta aagtcattcc agagccacca ataccaacag tgaaggtttc catgaatggt
     6181 tttgtgatga tgtgtggtaa ttcttttcca tgttgataag cttctaagtt atcaagcatc
     6241 agtgtattcc aaatcgggtc cattacagag ttgacgatga tttgtccgtg aagtccgaag
     6301 aaccataaga attggacaaa gaacaaagca atcaatgttg caggtaaact acttcccaaa
     6361 ccagttaatg gtttttggat cacttcataa acgacgtcat gtaagttagc attgaaaata
     6421 ccagtcatca cagcattgat tactaagaaa atagttagtg tcactacagc agggatcaaa
     6481 gcggcaaatg attttgttac tgcaggcgga actccatcag gcattttgat ctgccagccg
     6541 cgtttcgtga ttctgcagta gatttctcca gccaagaaag cagcgatcat tccaatgaac
     6601 attccttttg cgccaagacg atcaagtgaa agcacaccag tcacatcttc accgccagcg
     6661 gttttcattg caaaaggcgt aagaatcaag aagctggcaa aagacacggc accaccgaaa
     6721 ataccttcaa cgtcataaga ttttgataaa taatagccga taccaaaagt aacaaaaacc
     6781 gacatgatgc tcattgttgc attttgccca ttaccgaata aattcgataa agttcccttt
     6841 gttgcgtcac tgaaaaaagg caagttattg ataacgacaa cgatcgaacc gaacatcgtt
     6901 aaagggaagg aaagcatgaa agcatcccgc agcactgtaa ggtaacgatt ttgccctaat
     6961 aaattagcta agggcatgat tttctcagaa agcttgtcca taaaaccgtt catttttatt
     7021 cacctcaaat ttatttgcaa tcgattacat acaaagtata acgccaaaaa ttttaaatgt
     7081 ctagtcattt tcataaaaag tattgattta ttttttaggg ttcgttatga ttacggtatc
     7141 aagaaaaaag agaggaagta aaaaaatgaa aacctacaca ttcccagaaa atttttggtg
     7201 gggttctgct gctagcggac cgcaaacaga aggaagagta agtgatgatg gtaaaggaga
     7261 aaatatttgg gatcattggt atgaattaga gcctgaaaaa ttcttcgatc aagtaggacc
     7321 tgaaaaaact tcgcaagttt acacaaaata caaagaagat gttcagttaa tgaaagaaac
     7381 tggccataac acatttcgta catctatcca atggagtcat ttgattccag aagggacagg
     7441 tgaaatcaat caaaaagctg tttcttttta tcgagattat tttactgaat tgctggataa
     7501 tggtattgaa ccttttgtga acctttacca tttcgatatg ccactaccac tgcaagaaaa
     7561 aggcggatgg ttatcaagag aaacggtcga cgcttatgtt tcttatgcag cagcgtgctt
     7621 tgaactgttt ggagatctgg tcaaaaaatg gtttactcat aatgaaccaa tcgtacctgt
     7681 agaaggaggc tacttgtatc aattccacta tccaaatcat atcaatatga aagaagcggt
     7741 ccaagtaggc tatcatgaga atctagcaag cgcaaaggta atcaaagcct accatgaagg
     7801 cggacatgat ggtgagatcg gaatcatctt gaatctgaca ccaagctatc cgagagatga
     7861 aacgaaccca gaagatgtaa aagcggcgaa gatcgctgac gcattcttca accgatcatt
     7921 ccttgaccct gcagtgaaag gagagtttcc acaagagttg atcgaaattg tcaaagaatt
     7981 ggctataatg ccagagatcc atgaaggaga cctagaactc atccgtgaaa acacgattga
     8041 cctgctagga atcaattact atcagcctcg tcgaatcaaa gcaaaagaaa ctccaatcaa
     8101 tcacgaacat agccccatgc cagatgatta ttttgataat tacgacatgc ccaataaaaa
     8161 aatgaatcca tatcgtggat gggaaattta cgaaaaagga atctatgata ttttaacgaa
     8221 tacaagagaa aactatggta atatcaaatg ctatatttct gaaaatggga tgggggtcga
     8281 aggagaagaa cgatttgtta acagcgaagg aattattgaa gatgattacc ggatcgagtt
     8341 tgttacggat catttgaaat acgtccatca agcaatccaa gaaggaacca attgtgtggg
     8401 ttaccacatg tggacatgta tggacaactg gtcttggaca aatgcttata agaatcgcta
     8461 tggctttatc gctgttgatt tggcacaaga cggtaaacgg acgatcaaaa aatcaggtcg
     8521 ctggtttaaa acggtctctg aaaaaaacgg atttgatgcc tgatattttt tgataaaacg
     8581 ttcacaaaat gtttgttcta acactgtaat cgtgctacac taacagtgaa ggaggcgttt
     8641 acaatggtag atacttatcg taatatttta gtagcaattg atggttctga aaaggcagaa
     8701 aaagcatttc ttgaggcaat cacgattgcc aaacgaaatc aggcaacgtt gcacatcctg
     8761 tatgtcaatg aagtaacagg caattacttt ggtgattttg catttgttac aacaagcctt
     8821 caggaagaat tggatgaggt tgcggaaaac cagatgaaag aacatcgaaa cttggcaatt
     8881 gaaaaaggcc tgacagatat cgagacatat gttctttacg gttatccaaa gacactgatt
     8941 gctaatttcc atgaatcgaa agaaccaatc gatctgattg tcatgggggc gacaggtctg
     9001 aatgcggtag aacgtgcact agtaggttcc actacttcct atgtagtcaa ccacgcatca
     9061 tgtaacgtca tggttgtaaa ataaataaat taagggaaca gaaagcaaaa aagcataacg
     9121 cttcttttgc tttctgttcc ttttattttt ttgtaaaaaa ttactttacc tgatgaagta
     9181 atcatgctat tctaattaca acgacagatg gagtaatatg gaggaaagaa aatgatttca
     9241 agtgatggaa tacgcggata caatgatgcg attattttat cgatccttaa caaaaacgat
     9301 tcttatggat atgaaatttc taaaacgatt cgtgagagga caaatgattc ctatgtgatc
     9361 aaagagacaa cactttactc cgtttttgcc cgtttagaaa agaatcaact gattgtttcg
     9421 tatcctggag aagtgactca tggaaaaaag cggacatatt ataaaatcac tgaaataggg
     9481 cgtaatcttt tagaagaaaa aaagcaagag tggctgacga cgaaagacgt agtcgatcaa
     9541 tttttggagg gaaattaaat ggatacaatc cgtaattatt tagacagtct ttttatcgga
     9601 gtacctcaaa gtaccgagat agataagctg aaaactgatt tgttggcaaa tatggaagac
     9661 cattatcatg aattgatggg agaaggaaaa aatgaacagg aggccatcgg tacagtaatt
     9721 tcgacatttg gttcaatcga tgaattatta gaagaactag atgtcgaaaa aaaacatcaa
     9781 gctgacgaga cggaaacaaa cacagcttct atttatttaa gcgaagcaga aaactactgg
     9841 aaagaataca gagcggcaag tctccaagtg gcatcaggtg ttctattcat tagcttatct
     9901 tttgcaagtt ttcttttctt ttgttcagca ggatatgtgt tcatgggtat ttcttgtctg
     9961 attttcggta tagcattagc tgtcggtttt tttattgctt ctggtatgaa aatcacacgt
    10021 ttaaatcact ttttgcacca tcggaaaata cctgaaaaag tattagcaga agcaaaagaa
    10081 aaagaagaag agtatcagcg aagttttggc ttctcactga ttgcaggaat tggattatgt
    10141 attttttcac ttttcccact tttggcttct ttaatgtggt atatggatgg tagtatcggt
    10201 gcctctatat tttttgttac ggtaggaacg ggtgtcttct tgatcattta tggcagtcta
    10261 gtccgtcatt cttatcgtca attcactcaa agcgcttatt actggtgaat gtattcagat
    10321 ttgtaaaaat attctattta tccggcgtag aaaaaaagac tgtgacacgc ttttgtcaca
    10381 gtctttttta tatataataa tttaaaaatt catcatctaa atccgtagaa ttttctagat
    10441 tgcttaccca tgtaaaatcg ttatagacag atttcagttg acttctgcgc cattgtacag
    10501 ggataaaaag acgcatgcta tcttcattga atccgactaa taatttcttt ccgtcagtaa
    10561 tgatgggacg ttgtaacaaa gtaaaatgcg agacgatcag atcgacaagc tctgaggtcg
    10621 tacattggtc gatttggtct ttcaaatttt tataatcaat cgagcgttta gctaatagat
    10681 cgtcaaatcc gttttctgtt aatgacaata aataaaatat ctctttcctt gttaaaggct
    10741 gtttaggtgt gaaaattcgt tctctgtaag gcatttgatg gtctttcagc cagtttgcca
    10801 tcagatggta actatgtgtg cgagaagaat agatcgtaag cataaaaaaa ctccttaaat
    10861 agtccattaa tttgttagat ctgttgagat aaataatagg taaggagctg tgcataagca
    10921 ttgatcaaaa caacccaaac atcattagaa ataactttct aaagtcttaa acttgcgacg
    10981 agaagcaact agactaatag aaaaaatgtc ttagccattt ggcttcctgt ttgttttttt
    11041 gcttatgctg cagctcctcg ggaaagggtt ctaacaattt gaagaaggtt gatgattgat
    11101 ctagtttaaa ttgtgtgaaa tttgaaatct ggtgttttta ctagatgaat cacctaacaa
    11161 ctatgattat aacttataga acttctgttt tgcattcggt tttgttatag ttgttataaa
    11221 gttttatttt attacagaac atttttaatt aataaagaac agttagaagt taaaattgct
    11281 gattcacata gagtttatga cttcttggaa attctttttc aatcagtttt ttcatctgtt
    11341 tatgaaattc ttttttttca gtaaacataa aggtttgggt atcgtaacct tcttcatgta
    11401 ggaaatagat tattcctttt tctgtgtttt gcgtataagc ttttatactc ctgtcttttt
    11461 tgaaagaaca gatcgtatag ccatctattt ggtctggtag tcgtttgatt ttcttcaaaa
    11521 tgactttttt atcctcaagt ttcatttttt tcacctgact ttattttttt catatggaaa
    11581 tcatagcgcc tttggttata tgaaaacaag aaggatactg aaatatatat aaatcaaata
    11641 gtggttattt attattagaa tagcgaatac aaataaacga ccactatttt ctgatttatt
    11701 gcaaatgttt tttcaaataa atttgattac caagaaaagg tagtggtata tttactgagg
    11761 gatactttga aaaacatatg atagaaacag taacagtatt atgaaaaatc tttttataaa
    11821 aatggaggaa tcgatttgat ggaagatcag tatgtacaag caatgacgat cgcaggatca
    11881 gatagcgatg gaagcgcagg gatgcaagca gatatgcata cattctttac aagaaatgtt
    11941 tacggtgttt ctgtcatgac cgcatgtgtt gcaggtaatt cttacggaat cggagcaagt
    12001 gtgacattgc caacagattt tatcgacaaa gaatttgaac tgattgcgaa ggactttcaa
    12061 atacgtgcag ctaaaacagg tatgctagca gattcaaagt tgattgagac agttgtaaaa
    12121 aattaccaaa aatatgattt tggaccatta gtcgtggatc ccgtaatcgt aacgaaacat
    12181 ggaaatcttt tactagaaga atctgctttg caaagcttga aagaaaagct tgtccctttg
    12241 gccgaagtac tgacacctaa tttttatgaa gcagaaaagc tgactggacg gacattagca
    12301 gctgaagaag attttgtgca agcagcaaaa gaactgcaag atatgggtgc aaaaaacgtt
    12361 atgatcaaag gacatcatgc taaaaatgcg cagcaagaaa cagtcaatga ctacgtattg
    12421 ttcgaatcag gaaaatcatt ttggttaaat gcaccatttt atcctaccga ccggatcaac
    12481 ggaactggcg attcgctatc tgcatgtatt gcagctgagt tagcgaaagg aaaaacagtt
    12541 gaacaagcga tccgattggc aaaagactat gtaaaccgtg caattcgtga agaaataaat
    12601 gtagggcaca aatatggccc catcaatcat tgggcagctg gtgaattaga gtaaaagaaa
    12661 gaagttgtga aaaag
//
LOCUS       DACGEU010000080        12494 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.081, whole genome shotgun sequence.
ACCESSION   DACGEU010000080 DACGEU010000000
VERSION     DACGEU010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12494
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.081"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            158..730
                     /locus_tag="IXR40_002170"
     CDS             158..730
                     /locus_tag="IXR40_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003706982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HAQ4362000.1"
                     /translation="MTENKATQERTPQERLQEEQEHKEHVHHTKINAAAIADHLLGNM
                     HTLHVKLHQYHWYVKGANFFTLHEKFEELYNENEKWFDKLAERLITSGHKPASTTVEF
                     EKYSMLSEDAVNKYAKAEDMVENIIEDFRSTRDLTIRAIRLAQDEGDDALEDTLIAFK
                     NDLDKNIWMLQAFIGKEALEDDDALDEDED"
     gene            962..1579
                     /locus_tag="IXR40_002171"
     CDS             962..1579
                     /locus_tag="IXR40_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006845390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HAQ4362001.1"
                     /translation="MNYIAEKAHTKQYQKGEFLFRSQEKEDTLYIINRGKIRIYRLAD
                     SGKEQLVRILNPGDFTGEWTLFNPDAVHEEYAEATRDTVVCMIQQKDVQDFLEQYPAI
                     SLKLLAEMSKRLESSERQTTQVAVESVITRLVLFLAENVEPEMGNSPTITLPMAKKDI
                     ASYLGTTPETISRKFGELEDEGLIQQLSGKRIKIQDLDDLLLYSE"
     gene            1807..2145
                     /locus_tag="IXR40_002172"
     CDS             1807..2145
                     /locus_tag="IXR40_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003102891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362002.1"
                     /translation="MHCFWVIVAITLSAAGAFFVVPFTKNTIGGEAKTSNVVEADRLA
                     MEKEEEVVKGAGVIGHGKVAYYEASDQGDKSVFTVWFPWSLAGILFSITMTRMTRKIE
                     EMEQIEWDSY"
     gene            2130..2984
                     /locus_tag="IXR40_002173"
     CDS             2130..2984
                     /locus_tag="IXR40_002173"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003125438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HAQ4362003.1"
                     /translation="MGFVLGVLNPHVVEIGSVVIHWYGVIIAAGILAALQLSTKEAKK
                     KGLEEDTIIDMALWAIPIGLLGARLYYVLFELGYYLQNPGQILAIWNGGIAIYGGLIA
                     GGGTLYWYAKKKGTSLALVLDILAPNVLLAQSIGRWGNFMNQEAHGGPVTRQFLENLY
                     LPEFIIEQMNMNGTYYHPTFLYESLWSLLGFVLIVTIRNRKQLLRQGEVALSYVLWYS
                     VGRFFIEGMRTDSLWIGEWIRVSQALSLALFIGAIVVWFIRRQDYPPISYYSDGNKGQ
                     KKTIKMVN"
     gene            3131..3364
                     /locus_tag="IXR40_002174"
     CDS             3131..3364
                     /locus_tag="IXR40_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HAQ4362004.1"
                     /translation="MEKAILQLETLSCPSCMQKIEGAVKSVNGIDKDSIKVLFNSSKV
                     KTNFDSAVTSIEEIQKAIENVGYPVLKAKVKAV"
     gene            3562..5466
                     /locus_tag="IXR40_002175"
     CDS             3562..5466
                     /locus_tag="IXR40_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HAQ4362005.1"
                     /translation="MQQYILSKKNVITVISGLLIVLGFFSHFVLENVGLSEWSLIIAS
                     VFGITPIAIQAFQAMKVKVISIDVLVSIAAIGALFIQNYEESAIVTFLFLFGHYLEQR
                     TLNQTRSAIKELTEMAPESALKQMDNGEFEEVEVDDIDEGDILLVKTGAKVPVDGIVL
                     TGEGHINEASITGEAIPVNKLADAEVFAGTILENGTIQIRADRVGEDTTFGKIIELVE
                     EAQDSKSEAERFIDRFSKYYTPAVLVLAIVVWAFSQNIELAITILVLGCPGALVIGVP
                     VSNVAGIGNGARNGVLLKGSEVIQDFSNVDTIVFDKTGTLTVGNPTVAATELYEKDPA
                     ETLGYLASVERESDHPLAKAVLNQIGETNFYPVEGTEVVKGGGIVSSVAGHRVAVGNV
                     ALMEKENVTLSKKVQKDVKRFEQQGNSLVLTAVDGELKVLMGIRDQVRPGVKANLQEL
                     KDLGVKNLVVLSGDNQGTVDVVAGELGLTEAHGYMLPEDKSAYIGKLQQRGQIVAFVG
                     DGVNDSPSLALADIGIAMGSGTDVAIETSDVVLMNSNFSNLPHALGLVKATANNMKQN
                     IVISIGVVLVLLTSVFFSEWMNMSIGMLVHEGSILVVIFNGMRLMKYKLKGRKEQKEV
                     SAPAEKVKIS"
     gene            5776..6138
                     /locus_tag="IXR40_002176"
     CDS             5776..6138
                     /locus_tag="IXR40_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4362006.1"
                     /translation="MEKVCQVTIVHKEKVNVIKKKLDQKDFSNLLVLGKCFSDSSRIK
                     IFYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIRVFLKLSENLSMKS"
     gene            6155..6766
                     /locus_tag="IXR40_002177"
     CDS             6155..6766
                     /locus_tag="IXR40_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HAQ4362007.1"
                     /translation="MLQSIFSAIAVYISTSIDYLFILLIIFSQSHTKKGIRHIFWGQY
                     LGTGILVAVSLFAAYVLNFIPQDWIIGLLGLIPIFLGIRVAFVGEEEEEEEEVVEKLE
                     SRGTNRLFWTVALITIASGGDNLGIYIPYFTSLAFSEIIIALIVFAISVAVLCYISYK
                     LAKISFVSETLEKYERIIVPIMFIALGIFIMIENGTIQTLLGF"
     gene            complement(6868..7776)
                     /locus_tag="IXR40_002178"
     CDS             complement(6868..7776)
                     /locus_tag="IXR40_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HAQ4362008.1"
                     /translation="MSKSDKDHNHSNQNQPKKNIKIAFFINLIFSISEFFFGFLFNSV
                     SIMSDAVHDLGDSISIGFAWFFQGYSEKKQDERFTFGYNRFSLLGALITGVVLISGSF
                     FMIYRSVPRLIDPQPVNYSGMFWLSLVAIALNGYAAWILSKGTSKNESMLNLHMLEDV
                     LGWIGVLIVSILMNFTEAYRLDPILSILIALYILYKTVPEFFTTMKILLNGSPENVNV
                     KSLADSIKNVPAVKDLSHFHIWSLDGEENALIITVLIDPSDIDKAREIKEEIAEVAHK
                     SSVENHITIEITTSKEELEKGYSHNT"
     gene            complement(7818..8132)
                     /locus_tag="IXR40_002179"
     CDS             complement(7818..8132)
                     /locus_tag="IXR40_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HAQ4362009.1"
                     /translation="MDIKTTSPIDKGSILSISKLFKVISDPTRLSVLFLLQKKECSVG
                     NIAISLDMEQSAISHQLKTLKDARLVKSRREGKSMLYSLDDLHVFSILEQVLTHVNEL
                     EK"
     gene            8431..10362
                     /locus_tag="IXR40_002180"
     CDS             8431..10362
                     /locus_tag="IXR40_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HAQ4362010.1"
                     /translation="METIQEQQSQEKHNHNHNHDHDHDHGKMPVVLYFVGLALAVIAL
                     FLNEDYQLVQNVLFSIATISAGYHVILLEGLGETIENSKAQKKFIPNSHILMGLAAIG
                     ASLMGNFWEGTLLILIFSGAHFLEDYAEGRSKREITKLLEMNPTTARLILPDGSTKNV
                     DVSELKVGDQLQVLNGDQVPIDGVILSGSTSIDESSITGESIPKEKSKGDGVFGSTIN
                     GTGTFTMKVTKENKDTVFSKILQLVNQNQDNQTKAASIIQKFEPKYVTVVLIAIPLFM
                     LLAPFLLDWTWSQSVYRGLVLLVAASPCALAAATVSATLSTTSNLAKKGVLSKGSSYL
                     SQLADIKAIAFDKTGTLTKGKPEVTNYYFADSVNEENMIDIVVALEKESNHPLADAIL
                     RKFEQKNKLTIEVENQIGKGLTGDYKGRNYRIGKPTSFDDVSDEYSRLNNEWASEGKT
                     VVYVAVDEEVIGLIALMDVPSEYAKETIEYFRKQGIHTTLITGDSEMTGKAVAKQLGI
                     DEVIANVMPEDKSRIIDEQKEKYGVTAMVGDGVNDAPALVNADVGIAMGDGTDVAVEV
                     SDLVLMQNNLSKLVQSHNISSKMNRVIWQNIIFSMAVVAFLIVVSFLGLTDIAISVII
                     HEGSTLVVILNGLRLLKAV"
     gene            10655..11206
                     /locus_tag="IXR40_002181"
     CDS             10655..11206
                     /locus_tag="IXR40_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAQ4362011.1"
                     /translation="MGYNVQPLRSQQEINDFLFCLRRNKNAERDVFLFLIGINSGLRM
                     SDIVKLKKKDVITSKNPRIVEQKTGKTRILYLSSLQDLIHGYTAPLDPEAYLFPSTKG
                     GHLEVNTVYQMFQKVAKLLGRDDIGTHTLRKTFGYHYYKKTKDVATLMEIFGHSSEKI
                     TKRYIGINEDEISETLLNFRLGF"
     gene            11519..12061
                     /locus_tag="IXR40_002182"
     CDS             11519..12061
                     /locus_tag="IXR40_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362012.1"
                     /translation="MSIKETTQITRQLNAIYKAAHLLQEHFVDKKVSFVGEVSTVAII
                     FSTTNFMHLCGIDYRRGTHLFFQDALDRKINLQDIQIKTDGTTFQKLQVIGSLDLLLG
                     KHISIVGRGVYSSLRYDAAIRTRKKILALSLKQNGLIYIPISLLNLSSKEIGPGQKVT
                     GIFSEDLTSGELKMIMEVID"
BASE COUNT         4048 a         2093 c         2609 g         3744 t
ORIGIN      
        1 aatttaatag agaagcctgg cgtctattaa gaaataattt tcttgatgag cgtcaatttt
       61 tttaacggaa atctatccta tactaaattc agtaaagaaa aaggaggaat caaagaaagc
      121 tattttaaac aaaccaaaat tataggagga ataaatcatg actgaaaata aagctactca
      181 agaaagaaca ccccaagaaa gattgcaaga agaacaagaa cacaaggaac atgttcatca
      241 tacgaaaatt aatgcagcgg ccattgcgga tcatctttta ggcaacatgc atacattaca
      301 tgtgaaactg caccaatatc actggtatgt aaaaggagcc aatttcttta cgttgcatga
      361 aaaatttgaa gagttgtata acgaaaatga aaaatggttc gacaaacttg cggagcgtct
      421 aattacttct gggcataaac ctgcttcgac aacggttgaa tttgaaaaat attcgatgct
      481 ttcggaagat gcagttaata aatacgctaa agcagaagac atggttgaaa atattatcga
      541 ggacttcaga agcactcgtg acctaactat tcgcgcgatt cgtttagctc aagacgaggg
      601 tgacgatgct ttagaagata cattgattgc ttttaaaaat gacttagaca agaacatttg
      661 gatgctgcaa gcgttcattg gtaaagaagc attagaagat gatgacgctc ttgatgagga
      721 tgaagattaa ggtaaaagta gaagctgatt tagggattgg aattctttcc agtccttttt
      781 ccattttctt gatgtgcatc aatttttttg tagtaagaga cttatataat aaaagcagcg
      841 aatataaaca aaataaataa agggggagaa tgaattgact aaacataccc atcatgaaat
      901 tggcgaccac gcagcctgta tccgcttggt tccaatattc aatcacttag aggatagcgc
      961 gatgaattac attgctgaaa aagcccacac gaaacagtat caaaaaggag agtttctgtt
     1021 tcgttcacaa gaaaaagagg atactttata tattatcaat cgtgggaaaa tccgtattta
     1081 tcgattggca gactctggca aagagcagct agtgcggatc ttgaaccctg gtgatttcac
     1141 cggagaatgg accttgttca acccggatgc agtacacgag gaatatgccg aagcaacccg
     1201 agataccgtt gtctgtatga ttcagcaaaa agatgtccaa gattttctgg aacaataccc
     1261 agctatttct ttaaaactat tggcggaaat gtctaaacgg ttagaaagtt cagaacgtca
     1321 aacgacacaa gtagccgtgg agagtgtcat tacccgttta gttttgtttt tggcagaaaa
     1381 tgtggaacct gaaatgggca actctcccac catcaccctg ccgatggcaa aaaaggacat
     1441 tgcttcctat ttaggaacga cacctgagac catcagtcgc aaatttggag aattggagga
     1501 cgaaggattg attcaacagc tgtctgggaa aaggatcaag attcaggatt tagatgattt
     1561 attgctttac agcgaataat cggacacact tttttctaca cgttggtgtt ctgtcgctct
     1621 tcattaacaa cgggacagaa ctcagtgctt ttgcttccat ctgtccgttt ttggcttttt
     1681 taagacagaa cgaccttcat tcattggaaa aataaaagca caaacatgat aaccctcaag
     1741 tttttttgtt ttatttttct ttaagatagg gttgtcgaac aaaacgtaaa aataagtagg
     1801 gtgaatgtgc attgtttttg ggtgatagtt gccatcacgt tgtcagcagc gggggcattc
     1861 tttgtcgtcc ctttcaccaa gaacacgatt ggcggcgaag caaaaacgtc taacgttgtt
     1921 gaggcagata ggttagctat ggaaaaagaa gaggaagttg taaaaggagc cggcgtaatc
     1981 ggacacggaa aagtggcgta ttacgaagcg agtgaccagg gagataaaag tgtattcact
     2041 gtttggtttc catggagctt agccggaatc ttgttcagca tcaccatgac tagaatgacg
     2101 cgaaaaattg aagaaatgga gcaaatagaa tgggattcgt attaggcgtt ttgaatcccc
     2161 atgtggtgga gattggttct gttgtgattc attggtatgg agtcattatt gcagcgggca
     2221 tattagcggc tctccagttg agcaccaagg aagcaaagaa aaaaggactg gaagaggata
     2281 ccattatcga tatggcctta tgggcaattc cgattggact cctcggcgct cggctttatt
     2341 atgtgttatt tgaacttggt tattatctgc aaaatccagg acaaatcctt gcgatttgga
     2401 atggcggcat tgcgatttat gggggattga ttgcaggagg gggtacgcta tattggtatg
     2461 caaagaaaaa aggtacttct ttggcactcg ttcttgatat tttagcgccc aatgtattgt
     2521 tagcccagtc cattggtcgt tggggcaatt ttatgaatca ggaagctcat ggtgggccgg
     2581 ttactcgtca attcttggaa aatctttatt tacctgaatt tatcattgaa caaatgaata
     2641 tgaatggtac ctactaccat ccgacttttt tatacgagtc attgtggagt ttgttgggct
     2701 ttgtcctcat cgtcactata cggaaccgaa aacagctttt gcgtcaagga gaagtcgctt
     2761 tgagttacgt tttgtggtac tcagtgggtc ggttcttcat tgaaggtatg cgaacggaca
     2821 gtttatggat tggcgagtgg atccgcgttt cgcaagcctt gtctctggcc ctgtttattg
     2881 gcgcgattgt agtatggttt atacgcagac aagattatcc accaatttct tattattctg
     2941 atggcaataa ggggcagaaa aagactatta agatggtgaa ttgagcaaaa agataaaaag
     3001 aagtgcaaaa cttgatatgc gtcaattttc gtttgctaaa agtgagctat actacagttg
     3061 taaagaggaa aaggcagtgt tcattaatct gctgccgata aaataaaaac acataaagga
     3121 gataggaatt atggaaaaag ctatattgca attagaaacg ttgtcttgtc caagttgtat
     3181 gcaaaaaatt gaaggtgccg tgaaatcagt taacggtatt gataaagaca gcattaaagt
     3241 attattcaac tccagcaaag tcaaaaccaa ttttgattca gctgtcactt cgattgaaga
     3301 gattcaaaaa gctatcgaaa acgtaggcta tccggttctt aaagcaaaag tcaaggccgt
     3361 ttaacagatt aaatgaacta ggcaattctg gaagaaaagc tatttttcca ggattgcttt
     3421 ttttgttgca atccgattcg aggtgcttag aaacgataaa agagaacttt ctaaacttga
     3481 tgtcagtcaa ttaattactt aggcaattat cttatactgt gtttatcaat aaaagagaaa
     3541 ttaaatttgg agggaaaaag catgcaacaa tatatattaa gcaagaaaaa tgttatcacc
     3601 gtcatcagtg gattgttaat cgtactcggt ttcttcagtc actttgtttt agaaaacgta
     3661 ggactttcag agtggtcttt gatcatcgcc tctgtctttg ggattacgcc aattgccatt
     3721 caagcgtttc aagcaatgaa agtcaaagtc atcagtattg atgtcttagt cagtattgca
     3781 gcgattggtg cgctttttat tcaaaattat gaagaatcgg ctattgtcac gttcttattc
     3841 ttattcggac actacttgga acaacgaaca ttgaaccaaa cgcgatctgc tatcaaagaa
     3901 ttgactgaaa tggcacccga aagcgccttg aaacaaatgg ataatggcga atttgaagaa
     3961 gtagaagtgg atgatataga tgaaggggat atcttgctcg ttaaaacggg tgcgaaagtt
     4021 ccagtagatg gcatagtcct tacgggtgaa gggcatatca atgaagctag cattacaggt
     4081 gaagctattc cggtcaacaa gctagctgat gcagaagttt ttgcaggaac cattttagaa
     4141 aacggaacga ttcaaatcag agctgaccga gttggtgagg acaccacatt tggaaaaatt
     4201 attgaactcg tggaagaagc acaagattct aaatccgaag cggaacggtt cattgatcgc
     4261 ttttctaaat actacacacc agctgtcttg gttctggcaa ttgttgtatg ggcgttcagt
     4321 caaaatattg agttagcaat caccatcttg gttctaggtt gcccaggcgc attagttatc
     4381 ggagtgcctg tctcaaacgt tgccggtatt gggaatggtg ctcgtaacgg tgttctttta
     4441 aaagggagtg aagtcattca agacttcagt aatgtggata caattgtatt tgataagaca
     4501 ggtactttaa ctgtcggaaa cccaaccgtt gcagcgactg aactgtatga aaaagatcct
     4561 gctgaaacgc ttggctatct ggccagtgtg gaacgggaat cagatcatcc attagcaaaa
     4621 gcggtcttaa atcaaattgg agaaacaaac ttttatcctg ttgaaggaac tgaagttgtg
     4681 aaaggcggcg gaatcgtttc aagtgtagct ggacatagag tggctgttgg gaatgtggcc
     4741 ttgatggaaa aagaaaatgt cactctcagc aaaaaagtgc aaaaagatgt caaacggttt
     4801 gaacaacaag ggaactctct cgttttgaca gcggtcgacg gtgaattaaa agtactgatg
     4861 ggcattcgcg atcaagtccg tccgggtgtg aaagctaatt tgcaggaatt aaaagacttg
     4921 ggcgtgaaaa atctagtcgt tctttcagga gataaccaag gaaccgttga tgtggtcgcc
     4981 ggcgaacttg gtttgaccga agctcacggc tacatgttgc cggaagacaa atcggcttat
     5041 atcggaaaac ttcaacaacg tggtcaaatt gtagcctttg ttggagatgg cgttaacgat
     5101 agtccgtcct tagctttagc agacattgga atcgcaatgg gaagcggaac ggacgtagcg
     5161 attgaaacat ccgatgtcgt tttaatgaac tcgaacttca gcaacttgcc tcacgcatta
     5221 ggattagtaa aagccaccgc aaataatatg aaacaaaata tcgtgatttc aattggagta
     5281 gtgttggtct tgttgaccag cgtcttcttc agcgaatgga tgaatatgtc tatcggaatg
     5341 ttggttcatg aaggtagtat cttggtggta attttcaatg gcatgagatt aatgaagtat
     5401 aagttgaaag gtcgaaaaga acaaaaagaa gtatcagcac ctgcagagaa agtaaaaata
     5461 tcttaagaat aaattagaag aggctgagac aatagtccat ccttgaaatg acaaaagcgg
     5521 aaactcagat ttttaaatct gggattttcc gcttttttga gttcttgaaa aaaaataaga
     5581 gtatagagta tgttctttat aaaattaatt ttcgtgtaaa tgattaaaaa atttaataat
     5641 aaaatttaaa ttcctattaa gttgtaacac atgaaattgc ttataatagt gtattgaaat
     5701 taaggtagat tgacaaacga gtgatcaaat agatatacta ccttcaaacg accgtttgaa
     5761 tgtgaggtga gatgaatgga aaaagtttgc caagtgacta tcgtacataa agaaaaagta
     5821 aatgtaataa aaaaaaaatt ggatcaaaaa gatttttcaa acttacttgt gttagggaaa
     5881 tgtttcagcg attcttctag gattaaaatt ttctatgctt tagaaaccta taaggaaatg
     5941 tgtgtctgtg atttagcaga aatacttact gctagtgtcg ctacaacgtc acaccattta
     6001 cgttttttaa aaaaacatgg aatggcaaaa tcacgtcaag atggaaaagt agtttattat
     6061 tctttagcga atgaagacat cctttccgct attcgtgttt ttttaaagtt atcagaaaat
     6121 ctatctatga aatcttagtt tggaggaagt tattttgtta caaagtattt tttcagctat
     6181 cgctgtttat atttctacca gtattgatta tttgtttatc ttgctgatta tcttttctca
     6241 aagccacaca aaaaaaggta ttcgtcacat tttttggggt caatatcttg gaacaggtat
     6301 tttggtagcc gtaagtttgt ttgctgctta tgtgctaaat tttattccgc aagattggat
     6361 cattggtctt ctcggtctaa ttccgatttt cttaggaatc agagtcgctt ttgttggcga
     6421 agaggaggaa gaagaagagg aagtcgttga aaaactcgaa tctagaggaa ctaatcgctt
     6481 attctggaca gttgccttaa taacgattgc ttctggaggc gataatttag gtatttatat
     6541 tccatacttt acctcgttag ctttttcaga aatcattatt gctttaatcg tattcgctat
     6601 ctctgttgcg gttctctgct atatcagtta caaattagcc aagatttctt ttgtttccga
     6661 aacgttagaa aaatacgaac gaatcattgt ccctataatg tttattgcgt taggaatttt
     6721 tattatgata gagaacggga cgatacaaac gctactaggt ttttaaaaat cataatcacg
     6781 aaagataaaa agagaggcag cgactaatca aaatcgctgc cttttttgct tttcaaataa
     6841 tgaagtattt tttagcgtag aactatctta cgtgttgtgg gagtatccct tttcaagctc
     6901 ttctttgctt gtagttattt ctattgtgat atgattctct acgcttgatt tgtgtgcgac
     6961 ttctgcaatt tcttctttta tttccctagc cttgtctatg tctgaagggt ctataagaac
     7021 cgtgatgata agggcgtttt cttccccgtc cagtgaccaa atgtgaaaat gtgagaggtc
     7081 ttttacagca ggaacatttt taatggagtc cgccaagctc tttacgttta cattttcagg
     7141 cgaaccattc aataaaattt tcattgtggt gaaaaattca ggaacggttt tgtagaggat
     7201 ataaagtgca atcaaaatcg ataagatagg atccagacga tatgcctcgg taaagttcat
     7261 tagaatactc acaatcaaga ctccaatcca ccctaatacg tcttccagca tatggaggtt
     7321 caacatgctc tcgtttttgg atgtgccttt gcttaaaatc cacgcagcat atccattcaa
     7381 tgcaatagct acgagagaaa gccagaacat gccactataa tttacgggtt gtgggtcaat
     7441 caaacgtggc acactacgat agatcataaa aaacgagcca ctaattagca caacgccagt
     7501 tatcagcgcg cccagtaaag aaaagcggtt atagccaaaa gtgaaccgtt catcttgttt
     7561 tttctctgaa taaccttgaa aaaaccaagc gaatccaatt gaaatagagt cccctaaatc
     7621 atgaactgcg tcggacataa tggacacact attgaaaaga aagccaaaga aaaattcgct
     7681 tatagagaaa ataagattta tgaagaaagc aattttaata ttctttttcg gttgattctg
     7741 attcgagtga ttatggtctt tatctgattt tgacatttaa aaacctccta agtttgtatg
     7801 ctacatacta attggtttta tttttctaat tcattaacat gagttaagac ttgttcgaga
     7861 atactaaaaa catgaaggtc atctaaactg taaagcatac tttttccttc tcttcttgat
     7921 ttcactaagc gtgcgtcttt caacgttttt aattgatgag aaatagcgga ctgttccatg
     7981 tccagagaaa tagcgatatt tccaacacta cactcttttt tctgtaaaag aaagagaacc
     8041 gacaatcgtg taggatcact aatcacctta aatagtttgc ttattgacag aatagatcct
     8101 ttatcgattg gagaagttgt ttttatatcc atagtgtttt tattcctttc atatgacctt
     8161 ccgttcatat ctatattacc atatgagcga aacaatgcta atcttttgtt tataaaagag
     8221 aagtggcgtt ctctttatct tgacaaaatg tatatagcga tataaaatga gtatacaaac
     8281 atatgattaa ttagtcatat gtaaggtgga ttcattacga tttacttttg gaataaacga
     8341 aaggagtcag aaatagcaga aatttatgtg attcaagaag taaatgatgg aaaacaaagg
     8401 aattataaat tatataggga ggcaatagaa gtggaaacta tccaagaaca acagtctcaa
     8461 gaaaagcata atcataatca caaccacgat cacgaccatg atcatgggaa aatgccagtc
     8521 gttttgtact ttgttggttt agcattagca gtgattgctc tatttttgaa tgaagattat
     8581 cagttggtac aaaatgtttt gttctcaatc gctacaatca gtgccgggta tcacgttatt
     8641 cttcttgaag gccttggaga aacaattgag aattcaaaag cacaaaaaaa gttcatacct
     8701 aattctcata ttttaatggg attagcggca attggagctt ctttgatggg gaatttttgg
     8761 gaaggaacat tattgattct tattttttct ggcgcacatt ttttggaaga ttatgcagaa
     8821 ggaagaagca aacgagaaat aacgaaatta ctcgaaatga atccaacgac tgcccggtta
     8881 atcctgcctg atggtagtac aaaaaatgtg gatgtcagtg aattaaaagt gggagatcaa
     8941 cttcaagtgt tgaatggcga tcaagtacct attgatggcg tcattttgtc tggatctaca
     9001 tccattgatg agtcgtctat tactggagaa agtatcccga aagagaaatc caaaggagat
     9061 ggcgtcttcg ggagtacaat caatggaaca ggtaccttca cgatgaaagt caccaaagaa
     9121 aacaaagata cagtattttc aaaaatttta caattagtga atcagaacca agataaccaa
     9181 acaaaagctg cgagtattat ccaaaaattt gaaccgaaat atgtcacagt tgttttaatt
     9241 gccattcctc tattcatgtt attggctcct tttctacttg attggacatg gtcacaaagt
     9301 gtctatagag gattggtcct tttagttgca gcttcaccgt gtgctttagc agcagctact
     9361 gtctcggcaa cgctatcgac gacttctaat ttagccaaaa aaggagtcct ttcaaaaggt
     9421 agttcttacc tgtctcaatt agccgatatt aaagcaattg catttgataa gacgggcacc
     9481 ttgaccaaag gaaaacctga agtaaccaat tattattttg ctgattccgt gaacgaagaa
     9541 aacatgattg atatcgtagt agctcttgaa aaagaatcca atcacccctt agcagatgct
     9601 attctaagaa agtttgagca aaaaaacaaa ctaactattg aagtagaaaa ccaaattggt
     9661 aaaggattga cgggagatta caaagggaga aattatcgta taggaaaacc gacttcgttt
     9721 gatgatgttt cagatgaata tagtcgttta aataatgaat gggcgtcaga aggtaagaca
     9781 gtcgtatacg tagcagtaga tgaagaggtt ataggcctta ttgcccttat ggacgttccg
     9841 agtgaatatg ctaaagaaac cattgaatat tttaggaaac aaggtataca caccacatta
     9901 attactggtg actcagaaat gacgggaaaa gcggttgcta aacaattagg aatagatgaa
     9961 gtgattgcga atgtcatgcc ggaagacaaa tccagaatta tagacgaaca aaaagaaaaa
    10021 tacggcgtga ccgccatggt tggagacggt gtaaatgatg ctcctgctct tgttaatgca
    10081 gatgtgggaa tcgctatggg agatgggact gatgtggcag tagaggtatc tgatttagtt
    10141 ttaatgcaaa acaatttatc taaattggta caatctcata atatttcttc gaaaatgaac
    10201 cgtgttattt ggcagaatat tattttttca atggccgttg ttgctttttt aattgtcgtt
    10261 agtttcttag gcttaacgga tattgcaatc agtgtcatta ttcatgaagg aagtactttg
    10321 gttgttattt tgaatggact tcgattgcta aaggcagtct aaagaatgat tgcacaactt
    10381 caaattaatc gagtaataga gataattaag gattacacta cattttttat ctctattact
    10441 tgtttatatt tatctagatg ttcaaagtca aaatgatata tcaaccatac tcttgtggcg
    10501 cgggttgaat ataagataca tgaaattgga taaaatcatg tatcaagaat cctatcctta
    10561 tagggttctt tttttttact ccccctaaac acacgatttc gtgttgtaat aactataatc
    10621 atgtattcga acagactaaa aaggagggat tgtcatgggc tataatgttc agccactacg
    10681 gtcgcaacag gagattaatg attttttatt ttgcctgcga cggaataaaa atgcggaacg
    10741 tgacgttttc ttgtttctaa ttggaattaa cagcggtctg cgcatgtccg acatcgttaa
    10801 actcaagaaa aaagacgtga ttacctcaaa aaacccgcgc atcgtggagc aaaagacagg
    10861 gaaaacacgc attttatact taagcagctt acaggacttg attcacggct ataccgcacc
    10921 cttagatccg gaggcttact tgtttcccag tactaagggc ggccatttag aagtcaatac
    10981 ggtctaccag atgtttcaaa aggtcgcgaa gctgttagga agggacgata tcggcaccca
    11041 caccctacga aaaacctttg gttaccacta ttacaagaaa accaaagacg tggccacctt
    11101 aatggaaatc tttggtcaca gcagcgagaa gattaccaaa cgctacatcg gaattaatga
    11161 agatgaaatc agtgaaacgt tattaaattt tcggttaggt ttttgattgt attatataat
    11221 agataagcac agtaagacgg ttataatcac ccacagtatt ggacaaatca accttttttt
    11281 ggtatattat atatacaaat gagagcaggc tcatagtcaa cttgatataa atccggaaca
    11341 taagggtccg gcgggtggcg agcaccaaaa ctaaactcga tacaaatccg gaacgtaagg
    11401 gtccggcggg tggcaagcac caaaactaaa cctgtacaaa aggctgctct tttgagcagc
    11461 tttttttatt gggaaaaagg agcattcttc gcacgcggca aaaaaagaat acaaacgcat
    11521 gtctataaaa gagacaaccc aaattaccag acagttaaac gcgatttata aggctgctca
    11581 tctcttacaa gaacattttg tagataaaaa agtatccttt gtcggagaag tctcaacggt
    11641 agcgattatt ttttcgacaa ctaattttat gcacctctgt ggcattgatt atcgcagagg
    11701 cacacacttg ttttttcaag atgccttaga caggaaaata aatttacagg atattcaaat
    11761 caaaacggat gggacgacct ttcagaaatt acaagtaata ggtagccttg atttattatt
    11821 ggggaagcat atttctattg ttggcagagg tgtttactct tctcttcgct atgatgcagc
    11881 tattcgaaca aggaaaaaaa tattggctct gtctttgaaa caaaacggat taatctatat
    11941 ccctatctct ttgttaaacc tatcatcaaa ggaaattgga cctggacaaa aagttactgg
    12001 catttttagc gaggatttaa catccgggga acttaaaatg attatggaag tcatcgatta
    12061 atcattaata gtgatatgcg acgtcatttt gaagtaatta ttctattttg ggttataaaa
    12121 taaagcattt taagacgatt tcaaatcatt catgtgggtt atttatcacg gatgagcttg
    12181 aaatcgtctt ttatacgtat caaattgaaa tgttcggcat acaacctatc gttgttacta
    12241 cattactaat tgtcacttgt taaggaactt ggatcctttc taaacattcc ctagagataa
    12301 attttacttt atccctccgt taatatccaa tttaagcacc tttccgattc agggttaatt
    12361 tgcatatcaa gtgcagcttg tgttctagta agattagccc ttttagtccg gctgagttga
    12421 cttatggata taagatatgg tcatagcaaa tagatactac gtatagtctg ttaatttagt
    12481 gtcattaatc ttaa
//
LOCUS       DACGEU010000081        12433 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.082, whole genome shotgun sequence.
ACCESSION   DACGEU010000081 DACGEU010000000
VERSION     DACGEU010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12433)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12433)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12433
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.082"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..191)
                     /locus_tag="IXR40_002183"
     CDS             complement(<1..191)
                     /locus_tag="IXR40_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362013.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPGC"
     gene            complement(201..1016)
                     /locus_tag="IXR40_002184"
     CDS             complement(201..1016)
                     /locus_tag="IXR40_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAQ4362014.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLCESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            complement(1278..1721)
                     /locus_tag="IXR40_002185"
     CDS             complement(1278..1721)
                     /locus_tag="IXR40_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HAQ4362015.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     LSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            complement(1855..2193)
                     /locus_tag="IXR40_002186"
     CDS             complement(1855..2193)
                     /locus_tag="IXR40_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAQ4362016.1"
                     /translation="MYQVKKSRSIAMELRLLKYFWTIAEEGTISQAAEVLHLTQPTLS
                     RQLKELEEELGTELFVRENRKMILTEAGYFLKKPSRRNFRFNESNHSRIREQKKTIIQ
                     RPIYDRLCGS"
     gene            complement(2181..2558)
                     /locus_tag="IXR40_002187"
     CDS             complement(2181..2558)
                     /locus_tag="IXR40_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAQ4362017.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKEIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            2782..3975
                     /locus_tag="IXR40_002188"
     CDS             2782..3975
                     /locus_tag="IXR40_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAQ4362018.1"
                     /translation="MTTYQRKVLLSTSAGIALENMDIMFLAFSLSSMITSFHISGTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFIMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            complement(4141..4563)
                     /locus_tag="IXR40_002189"
     CDS             complement(4141..4563)
                     /locus_tag="IXR40_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAQ4362019.1"
                     /translation="MQTFLTKVSQKKIKMIHLLLETERWCSIEELQNELKVSSKSILN
                     YLTDLEELFQKYPDKVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQ
                     HPEKNLEDYADAQYTSVSTVFRYAKLLVKYFEMTDVKE"
     gene            4958..5152
                     /locus_tag="IXR40_002190"
     CDS             4958..5152
                     /locus_tag="IXR40_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362020.1"
                     /translation="MVAGSLLSGCGATTSTTQSTSSDQASSSSTTISESTADSSKEQE
                     QIEKKKEEKQKAEKAALEKK"
     gene            5149..5595
                     /locus_tag="IXR40_002191"
     CDS             5149..5595
                     /locus_tag="IXR40_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362021.1"
                     /translation="MTEAESALSQAEANPTKENYATASAAIQALPENKQELTSRLAAI
                     DSTIKAKEAEEERKKQEEIARQQAEQAQQEAIAQQQAEQARQEAIAQQQAEQARQQSA
                     AEQASQQAQAAAPEQNNEQTVYVTPTGSKYHTHKCGNGTYTPATLS"
     gene            complement(5805..6977)
                     /locus_tag="IXR40_002192"
     CDS             complement(5805..6977)
                     /locus_tag="IXR40_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAQ4362022.1"
                     /translation="MNKSRIRILDIFMAIILVVGIGIFSYPFVEDSLNDFLAQQMIIH
                     YQKQASNKNSEEIKKQQEKMTKKNQQLAEQNVSPGIGSFNQAVDAKALKDLPSNAFFM
                     EHMLGVIEIPKINVSLPIFDQTTEIFLQKGTSLLEESSYPTGGKNTHAVLSGHRGLPE
                     AKLFTDLPKLKKGDQFFIQINGKTLAYQVEKIQVVLPDEVDSLGIQKGRDLVTLLTCT
                     PYMVNTHRLLVTGHRIPYQAKEAKKAIQGIDQWKKWKFFIWFIGILLGSIGLVWLLIA
                     YLDSLAIAKRNYPLSFYVKNTNGRPIEGMVFSVKTLNGKHYITREKVPFVKASDEYGL
                     VRFSDLKGRNYRLQHEELLLKIHVKHKHSKQFSMKLKKGRYKLRKEKEVYYLIEKE"
     gene            complement(7183..7998)
                     /locus_tag="IXR40_002193"
     CDS             complement(7183..7998)
                     /locus_tag="IXR40_002193"
                     /inference="COORDINATES: protein motif:HMM:NF033902.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HAQ4362023.1"
                     /translation="MTGFDENTGVALYDPAESALTFTTDTEGSISVNGLIDGNYTLVE
                     TKAPDGYQLTNPQKETTFIVKNGKLQQTTGIIHGADEANLGNPNGVVNRENTTTDNTI
                     TVENVQNYGDFHFIKQDVNTQEKLADAEFSILRAKDPTVKLMKKIANLASGEYPYAWS
                     DEVTGSDWEEVKLISDSEGKFSIEGLKQGAYCLQETKAPEGYALPKNEAAYTEFTVDD
                     DPTTSDETTIDNQPKGILPSTGGMGIIVFILVGTALVGGAVIYFKKRHQETEA"
     gene            complement(8148..8594)
                     /locus_tag="IXR40_002194"
     CDS             complement(8148..8594)
                     /locus_tag="IXR40_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HAQ4362024.1"
                     /translation="MKNIKTKIWTFLGTAIMLLPFVLGLGTAEVSAAVSPTPENVTVN
                     LHKLKFTSAPENQINNGTELTFPNSEPLNGVEFNVYDITATYYPSKDTAVPADATPFA
                     SVTTSGEGLANLTLPGKSDGKDAVYVFVETPKPGVETSPNIVLSLP"
     gene            complement(8591..9595)
                     /locus_tag="IXR40_002195"
     CDS             complement(8591..9595)
                     /locus_tag="IXR40_002195"
                     /inference="COORDINATES: protein
                     motif:HMM:NF037639.1,HMM:TIGR04226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HAQ4362025.1"
                     /translation="MTDSSNHKLTTIHLYPKSEQKIPAALTLTKTVENKQTDFADGDK
                     VPYLITVTIPENINEIGTYTIKDTADPQLWLEPETIDFLIGGDKIHTFHTQKIKHGFV
                     LSDSGKDLSSFAGKKLTIRYQMTLKENSEKTTFDNDVRLTTDNQTVETHLAIQTGGKQ
                     FVKVDRQTKQKLADAQFLVKKNDQYLAQENGINHWVAKDDSRATIFTSSKDGTFSVHG
                     LSFGSYELVEIKPPKGYILSQSTILFEVEKGSYDPLHPIPLEIINEPKANPTNNGKTP
                     VQMQTNGPSNEKNGGSFPKTSEEMLGGFSILGLLLVLSTGTAWFYKKQQKGNNRREIK
                     "
     gene            complement(9635..9964)
                     /locus_tag="IXR40_002196"
     CDS             complement(9635..9964)
                     /locus_tag="IXR40_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HAQ4362026.1"
                     /translation="MFESDKMPSISQNDGINIPDNFQGVKGLNGVTFAIYDVSDEFYK
                     LRSEGSSVEDAQRKLAQKSDSEKILAENVTKTVDEEEGIASFSASDKDEQGRDAVYRF
                     TEIKTSD"
     gene            complement(10090..12417)
                     /locus_tag="IXR40_002197"
     CDS             complement(10090..12417)
                     /locus_tag="IXR40_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAQ4362027.1"
                     /translation="MKMIKKTQNKIQRICQKHFVSRLKAVSKRKYLHPIMISIILIFT
                     FLGSLSSIYVNVYTETSNFANQTTEETNSPPYSEIQSIESTNQSSNNETTSTTSSTQL
                     IDPTEKEITAAKAAGEKAYSETGRSQTFSTVAATANFNGHTIPDGYTVIYAKDGVIVA
                     VNGSMSADKTALQGVTKAIAFIDNRPDIHNLFIGSTVNGTTITFPKSIYMGVATAGNT
                     IDSVTPNADKSYSFTPSTWGGLPAGGGMSTFSIGIQLANDIPFTGYSIKNGQIVDGKG
                     NVSNFPTYQAATVQVNANRTGTFSYTVNGGAAKIGTYGTTLSGIHVGDKVVITPTAVT
                     GYSFAQTNGSFTALESNVDTVTYTGKQTPITIKYQDYFGQMIAPSKIMNLTYGSAAQD
                     LTTNTPTINGYTFTAVSAIETKNQSAMSVLASLDTNGNVIVKDANGKQISEVILYYKT
                     NATVSINANGSKYYDGLSVVPIVKYAFNDKTESTSLLNNDLSIDQITWNPTDFKAMNE
                     KGVEVTAPTEIGTYTSWQLTKSGLAKLAARTNYLFTIVQTSDVYTIKQISGAVELSGS
                     KTYDGKAGVPSIHVKLAEGVTSSLTPVQVALSSMDYTADAQSAKNMVNAGSYTIKLTN
                     SGIDKVKAANPKLSFTDIANTSGTYTIYKANAVITVDDAAFNYDAQSHSISVGNLHVT
                     GVVLGESLDYTLTVNSRTDIGSQIVTISLGEGSVNNNYTIIATDTAKLTINPTLLLPS
                     TGGIGLLPFVFLGLIFIFSGFFYFIHRKKKAGEQR"
BASE COUNT         3514 a         2431 c         2272 g         4216 t
ORIGIN      
        1 atgcaacctg gaccaataaa aagtaaagaa aaaataaagg aaaagacatt ccttccatct
       61 atcgacaaaa ggaacgcagc tgctatatac aagatattga cacaccaaaa acaaaggcta
      121 cttgccaatg attgatacaa ccaataaaag aattccatat aaacattttt gtcaaaacgc
      181 tgctctttca taatcacctc ctattccttc attcctgatg aagcgatccc ttctacaaaa
      241 tatttttgca tcgctaaaaa tataaaagca acaggaagaa cagaaacaac tgaggcagcc
      301 atgattaatg cgtactctgc atcaaatagc ccaataaaca ttttcaaccc taactggatt
      361 gttttatttt ccgtagaaga caaataaatg aatggcccca tataatcgtt ccatgtatta
      421 acgaatgtga tgatcgtcaa actggcaatc gccggttttg taagaggtaa aatgatcttg
      481 cgatagattc cccactctga taagccatcg atccgcgcac tctcacataa agaatctggg
      541 atactactgt agtattgctt caacaagaac acaccaaaag cattgaacgc ttgtaatagc
      601 accaacgacc acaacgtata tgttaaaccc acttttctca tcataatgaa ctgcgggatc
      661 atataagact gccaagggac agcaatcgtg ccgatatatg ctaaaaataa aatatcgcgc
      721 cctttaaaat ttagtttaga aaacccgtaa gcagcaaaac tagaagtaaa caactgaatc
      781 aacgtgatca caacgcttaa aaaagctgta ttcttaaaaa atgtcactaa aggaatacga
      841 gaccaaataa ccagataatt ctctaaatgc caagttttag ggatccattg aatcggaatc
      901 gtgaacactt cattatttgc tttgaatgaa gcagaaacca tccataaaaa aggaatgatc
      961 gtcaataaag ctaatacaat cagcagaatc atacccaacc attgaataaa gggcatgttt
     1021 tttgaacgaa tttttgcttt ttttctttca tttcgaacac ctccaaagtt ataatcttca
     1081 tttctttgta atgattacaa tccagaacaa cggttattat agctgattca tttccgttct
     1141 tcttatgttt gtaagcgctt atttaacaag ttatgtaaat ctctttattt tttttgattt
     1201 aaaaatgaaa aaatacaaaa gcaagactgt catacgtctc gcttttgtat tgaaatttct
     1261 tcgattagag atacttatta ctgttcaaaa gcttctttga aacggtgaat caattcattg
     1321 actacaggtg ataaaatccg attctttttc cagactagca tgcagttcgt ttcaatcatt
     1381 gggtcaagcg gaacgaatgt cactcgcttt gaaagatgac ttacagcacc ttctatgact
     1441 aaagcagcac ctacctgatt ctcaattagc gcaaatacat tgaaaatcaa attgtacgtt
     1501 cctgtgatca gcaactgctc cttttttatg cctaaccagt cagcaaacat tcgctgtatt
     1561 tctggacgct ttgagatcaa aagaggtaca ttcgcaaagt cttcttttgt tatcacgtct
     1621 ttttttgcta aaacagaatt ttctaaaatg agcaatcccc atttttcctt tcttggtaac
     1681 aaaatcgttt cgtatttctc tgtatctact ggatctagca aaatcgctaa atctaacagg
     1741 cttttttcta gtcactccgt gatatcatca cttgttccgc tgtggatatg aaattgaacg
     1801 ctgggataat cacggatcaa cttttctagt aatagtgcca atgtattcga attatcagct
     1861 tccacacagc cgatcgtaaa tcggccgctg aataattgtt tttttctgtt ctcgaattct
     1921 tgagtggttt gattcgttaa atctaaaatt tcttctgctc ggctttttta gaaaataacc
     1981 tgcttctgtc aagatcattt tgcggttttc gcgtacaaac agttctgttc ctagttcctc
     2041 ttctaactcc ttcagttgtc ggcttaaggt tggttgtgta agatgtagaa cttctgcggc
     2101 ttgagagatt gttccttctt ctgcaattgt ccaaaaatat tttagtaagc gtaactccat
     2161 agcgatgctc cttgattttt ttacttgata cattccattt tatttctaga taacacacga
     2221 tcatatttct tgatttttcc ttgtaaacgt tccaaacact cttgcatttc agcaatttct
     2281 ttcgtcaaaa gttcactttc ttcaatcaaa agcttacgcc gctcaaatac agttgcttct
     2341 ccttcgctag ataggcgaat atattcaatc aaagactcga tcgataatcc ggcatttcgc
     2401 atacagatcg taaagtcgac ccattttagg tcttcttctg tataatcacg gattccgcct
     2461 tttgtccgat taactggtgg aatcaacccg attcgttcat aatagcgcaa tgtatcggcc
     2521 gaaatgccct tttcttcact gacttgtttg atattcatct gatcactctt tctcttaatt
     2581 tcttgccact ttacttatgt attttattta ttctacaact tcaagtgtac tccaagtcaa
     2641 tactcatttc tattaaaact aagctggatt atctatatcg gttgtttgtg tattatttca
     2701 aataaaaaag tcttgttttt ttattctttt ttggatatac ttttaacaat ttagggaaat
     2761 tttaggaaaa ggggtataaa aatgacaacg tatcagcgaa aggtattatt atcgacatcg
     2821 gcgggaattg ctttagagaa tatggatatt atgtttttag ctttttcatt atcttcaatg
     2881 attacttctt ttcatattag tggtacgcaa gcgggtttca tttcaacgat cactaatttg
     2941 gggatgctca ttggaggtat tttttttggc atcatagctg ataaatatgg acgtgtgaaa
     3001 gtattttctc aaacggtcct tctgttttcg attgcttctt tattgatgta ttttgcttca
     3061 aacatctact tggtttatct ctttcgcttt atcgcaggtg taggagcggg aggagaatac
     3121 ggggcgtgta tgtccttgat ttccgaaagt ttttcaaaaa aacaaattgg acgagcttct
     3181 tcggttgctg gtattggtgc gcaggtcggt gcggctttgg ctgcgatttt agctgctgtg
     3241 atcattccaa cgtttggttg gaagatgttg tatgtcgtag gtgtactgcc ggtgttgatg
     3301 gtcttgttca ttcgtcgcgg cttgactgaa ccaaaggaat tcaaatctgt acaatctgcc
     3361 gaaaagaaaa ccaaacttag cagactgttt gaatcaaaac atcttgcttg gcaaacatgt
     3421 ggccttagta tcatggtaac tgtccaaatt gccggctatt ttgggttaat gaattggctg
     3481 ccttcaatta tgcaaaatcg attagggctt tcggtttctg ggtcttcatt gtggatggtc
     3541 agtactattt taggcatgtc tttggggatg atgacttttg gcataatcat ggataaattg
     3601 gggcctaaac tagccttttc tttgttttta atttgttcat ccttatctgt ctatctactt
     3661 gtgttagccc atagccagtg gagtttggta gcagccgctg tgatagtcgg ctactttatc
     3721 aatggcatgt atggtggata tggcgcagtg attagtagtt tgtatccaac agaaatccgc
     3781 gcgacggcga ataatttcat tatgaacctt ggacgagctg ttggtggttt ttcttctatc
     3841 gtcatcggtt tcttgatgga tcattatagt ttaactgccg taatcttgtt tttgagcggt
     3901 atttacctag tcagtctgct ggtcttgaca actcttactg gtgttacagc attaagggaa
     3961 agcttgcagc attgatagtt gagtctgtaa atgacaagaa agaggtgtgg caaaagcttg
     4021 catctgcggt aataagacca gccaaatcaa aaacatgaga cactgtttcc gtttggctgg
     4081 tcgtattact tgatgcaggg cagctttttc aactgctaat ttccttctat ctggcggcga
     4141 ctattctttg acgtccgtca tttcaaagta ctttactaat aacttagcat aacgaaaaac
     4201 tgtggataca ctcgtatatt gagcgtctgc ataatcttcc aaatttttct caggatgttg
     4261 atacatgaat tcaatcaaat gataattata tgattttctg tagaaatgaa gataaataat
     4321 gtagattggg aagttctcct gcttttccat agaaaagcgc cgattattct cattcttcaa
     4381 aatgacctta tcaggatatt tttggaacaa ttcttctaaa tctgttagat aattcaagat
     4441 agacttactt gataccttca attcgttttg tagttcttct attgaacacc aacgttctgt
     4501 ttcaagcagt aaatgaatca ttttaatttt cttttgagaa acttttgtta aaaaagtctg
     4561 catattttct cctcctgtat ctactttact atactacata caagaaaaaa aacggataca
     4621 aatatcatat tgtcacaccg tcaatagtgc ataaacctgt tattatttct ctttttttcc
     4681 taagtattct attgatatga atcatttaat cgtttattat ataaatgtca ataatctaat
     4741 aataaaataa cgtacatatt ttattattgc atacttaata acagaactat agcaaaaaat
     4801 cccgtgtatc aacacgggat tagattaagt ttcctcaatc actattcata acacaattat
     4861 tataacaagt aagtaaacaa ttgaaaagga catttattga aaacggttgt tttttactta
     4921 aggaggaaat ttagcgaaaa aattagttgc attgtttttg gtcgcaggaa gtttgttgag
     4981 tgggtgtggt gctactacgt ctactactca aagcacaagt tcagatcagg cttccagcag
     5041 cagtaccacg atctccgaaa gtacggcaga ttcatcgaaa gaacaagaac aaattgaaaa
     5101 gaaaaaagaa gagaaacaaa aagcggaaaa agctgcacta gaaaaaaagt gacagaagcg
     5161 gaatctgctt tgtcacaagc tgaagcaaat cctacaaaag aaaactatgc aactgcttca
     5221 gcagctatcc aagcgctacc tgaaaacaaa caagagttga caagccgtct tgctgcaatt
     5281 gattccacaa tcaaagcaaa agaagcagaa gaagaacgga aaaagcaaga agaaattgca
     5341 cgacaacaag cagaacaagc gcaacaagaa gcaatcgcac agcaacaagc agaacaggcg
     5401 aggcaagaag caatcgcaca gcaacaagca gaacaggcgc gacagcaatc agcagctgaa
     5461 caggcctctc agcaggcaca agccgcagct cctgagcaaa ataatgaaca aactgtctat
     5521 gtcacaccga ccggttcaaa ataccataca cataaatgtg gaaatggtac gtatacccct
     5581 gccactttaa gctaagctca agctcgtggt ttaacccctt gctccaaatg ttatggaaac
     5641 taattcaaaa gttatactat aataataaaa ttcttctgaa acataaaaaa atagaagatg
     5701 gcgttccaga tagtaaacca aaaataacag tttacacgtc catttcgtca gcttctctct
     5761 tttttcattt agtctgttcc ctctgctttt ttggacatct tcattcattc tttctcaatc
     5821 aaatagtaca cctctttttc ttttcgcagt ttatatcttc cttttttcaa tttcattgaa
     5881 aactgtttcg aatgtttatg ttttacatgg attttaagca ggagctcctc atgttgcaag
     5941 cgatagttcc tgccttttaa atcagaaaat ctcactagtc cgtattcatc agaagctttc
     6001 acaaatggaa ctttttctct agtaatatag tgtttgccgt tgagcgtttt tacagaaaag
     6061 accattcctt cgattggtcg tccgtttgtg ttctttacat aaaaagataa aggatagttt
     6121 cgcttagcga tggccaaaga atctaaataa gcgatgagta gccaaactaa gccgattgat
     6181 ccaagtagta taccgataaa ccaaataaaa aatttccatt ttttccattg atcaattcct
     6241 tggatcgctt tttttgcctc ttttgcttga taaggaatac gatgccccgt cacaagcagt
     6301 cgatgtgtat tgaccatata aggagtacag gtaagcaaag tcacgagatc tctgcctttt
     6361 tggataccca aagaatctac ttcatcaggt aagaccactt ggattttttc tacttgatac
     6421 gccaatgtct ttccattgat ctggatgaaa aactggtctc cttttttcaa cttaggcaaa
     6481 tctgtaaata attttgcttc tgggagtcca cgatgcccag aaagaacggc atgggtgttt
     6541 ttcccgccag tcggataaga actttcttcc aataatgacg ttcctttttg caaaaatatt
     6601 tccgttgtct gatcgaatat aggtaagctg acattgattt ttgggatttc gatgactcca
     6661 agcatatgtt ccataaaaaa ggcattacta ggtaaatctt ttaatgcttt tgcatcaact
     6721 gcttggttga aactgcctat ccctggtgat acgttttgct ctgccaactg ttggtttttc
     6781 tttgtcattt tttcctgctg tttttttatt tcctctgaat tcttattcga tgcttgcttt
     6841 tgataatgga tgatcatttg ctgggcaaga aaatcattca gtgaatcttc tacaaaagga
     6901 taagaaaaga tcccgatccc aacgactaaa atgattgcca tgaagatgtc cagtattctt
     6961 attctgcttt tattcatcat gtccacctat tttctaatat gtatatgaag aggttgtgaa
     7021 atcagcgcct tgacctgagt attagcgaag caaacggcaa aatagttcct cctattttgc
     7081 cgtttgttga gcgaatacca agagaccgac cacttgtcac aacctttctc cccatttgaa
     7141 tcactatcgt ttatttatcg tatgattttt gtttccaata gtttaagctt ctgtttcttg
     7201 atggcgtttt ttgaaataga tcactgctcc tccaactaaa gcagtaccta ccaagatgaa
     7261 tacgatgatc cccataccac cagttgaagg caagattcct ttaggttggt tatcgatcgt
     7321 tgtttcatca gaagttgttg gatcatcatc tactgtaaat tcagtgtacg cagcttcatt
     7381 cttaggtaat gcgtagcctt ctggtgcttt tgtttcttga aggcagtatg ccccttgttt
     7441 cagcccttcg attgaaaatt tcccttctga atcagaaatc aatttcactt cttcccagtc
     7501 agaacctgtg acttcatctg accaagcata tgggtattct cctgaggcaa ggtttgctat
     7561 ttttttcatt aatttaacag ttggatcttt tgctcttaga atagaaaatt ctgcatcggc
     7621 taatttttct tgcgtgttca catcttgttt gatgaagtgg aaatcaccgt agttttggac
     7681 attttctaca gtaatcgtgt tatccgtagt tgtattttcc cgattgacta caccgtttgg
     7741 attcccaaga ttggcttcat ctgcgccatg gatgataccg gttgtttgtt gcaattttcc
     7801 gttttttact ataaaagtag tttctttttg tggattggtt aattgataac catctggtgc
     7861 ttttgtttca actaaagtat aattgccgtc tattaatcca ttgacactga tggatccttc
     7921 agtatcagtt gtgaatgtca acgctgactc agcaggatca tagagagcga caccagtgtt
     7981 ttcatcaaaa ccggtcacga attgattctc tgaatttttg atctggaatt gcgcccctgc
     8041 taacttatct acccctgaaa agttcccagc tttctggatt ttgatattgc tttctttgat
     8101 gacattttta gcatataggt gaatcgtgtc taaaggtttg tcagggtcta gggtaagctt
     8161 aacacgatat ttggcgacgt ttcgacaccg ggctttggtg tttctacaaa gacgtataca
     8221 gcatctttcc catcagattt acctggaaga gtcaggttag ctaatccttc accagaagtc
     8281 gttacacttg cgaagggtgt agcgtctgct ggaactgctg tgtctttact tggatagtac
     8341 gtagcagtga tgtcatatac gttgaattca acgccgttca acggttcgct attcggaaat
     8401 gtcaattccg ttccgttgtt tatttgattt tctggtgctg aagtgaattt caatttatgc
     8461 aaattaaccg taacattttc tggtgtaggt gatacggctg cagaaacctc tgcagttcct
     8521 aggccgagaa cgaaaggaag cagcatgata gcagttccta aaaacgtcca tatttttgtt
     8581 ttgatgtttt tcattttatt tccctcctat tgtttccttt ttgttgtttt ttataaaacc
     8641 aagctgtccc tgttgaaagg actagcaata accctaaaat tgagaaacct ccaagcatct
     8701 cttcgcttgt ttttggaaag cttcctccat ttttttcatt tgatggacca tttgtctgca
     8761 tctgaactgg cgtttttcca ttattcgtcg gatttgcttt tggttcgttg atgatttcca
     8821 atggtatagg atgaagcgga tcataactgc ctttttcaac ttcaaagaga atggttgatt
     8881 gactcaatat atatccttta ggcggtttaa tctccactag ttcgtaactt ccaaaagaca
     8941 atccatggac agaaaatgtt ccatctttac tggaagtaaa aatcgttgct cttgaatcat
     9001 ctttggctac ccaatgattt atcccgtttt cttgcgctaa gtattggtca ttttttttga
     9061 ctagaaattg agcatctgct agtttttgtt tcgtttgccg atccactttg acaaattgtt
     9121 tgcctcctgt ttggatggca agatgtgttt ctactgtttg attgtcagtc gtcaaacgta
     9181 catcgttatc aaatgtcgtt ttttcactgt tttctttcaa tgtcatttgg taacggatcg
     9241 ttaatttttt tccagcaaac gaactaagat cttttccaga atctgataag acaaaaccat
     9301 gttttatttt ttgtgtgtga aatgtatgaa tcttgtctcc accaatcaaa aaatcgatcg
     9361 tttctggttc tagccataac tgaggatcag ctgtatcttt gatcgtatag gttcctatct
     9421 cgttgatgtt ctcaggaatt gttacggtga tgagataagg gactttatcc ccatctgcaa
     9481 aatctgtctg cttattctct actgtttttg ttaatgtgag tgcagcaggt attttttgtt
     9541 cgctctttgg atacaagtgg atggtcgtca atttatgatt agatgaatct gtcacaggaa
     9601 gcacaacgac aaatggtgct gatttttctt ttacttaatc tgaagtcttt atttccgtaa
     9661 atcggtaaac agcgtcacga ccttgctcat ctttgtccga tgcactaaaa gaagcaatgc
     9721 cctcttcctc gtctactgtt tttgtcacat tttctgccag tattttttca ctatcacttt
     9781 tttgtgctag ttttctttgt gcgtcttcca cactacttcc ttctgaccgc agcttgtaaa
     9841 attcatccga gacatcatat atagcgaaag taacgccgtt caaccctttt actccttgaa
     9901 agttatccgg gatatttatt ccgtcgtttt gactgatact tggcatctta tcgctttcga
     9961 acattcgatt atgcaaagta aatgtaatag gtgattctct agctgacaca gtcggagaac
    10021 ctataaaaaa gaccagtagg ataaaaaaga gaacagcaaa tatatccaca cgtacatttt
    10081 ttgttttttt catcgctgtt cacctgcttt tttcttacga tggataaaat aaaagaagcc
    10141 agaaaaaata aagatcagtc ctaaaaagac aaagggcagt agacctatcc cacctgtcga
    10201 aggaagcaag agagtcggat tgatcgtcaa cttagcggta tctgttgcga taatcgtata
    10261 attattgttt acacttcctt cgcctaaact aatcgttact atttgtgatc caatatctgt
    10321 ccggctgtta actgttaggg tataatccaa tgattcgcct aagacaacac cggtaacgtg
    10381 gagatttcca accgaaatcg agtgactttg ggcatcataa ttaaaggcag cgtcatcgac
    10441 agtaatcact gcgttagctt tatagatggt ataagttcct gatgtgttgg ctatatcagt
    10501 aaatgacaac ttgggatttg ctgctttgac tttgtctatt ccgctattcg ttagtttaat
    10561 tgtatagctg ccagcattaa ccatattttt tgctgattgt gcatctgctg tgtaatccat
    10621 actgctaagt gccacttgta ctggagtaag cgaactagtg acaccctctg ctagcttgac
    10681 atggattgac gggacacctg cttttccatc atatgtctta ctgccactga gctctaccgc
    10741 accgctgatt tgcttaatcg tatagacatc agatgtctgc acgatagtaa ataaatagtt
    10801 tgttctggca gctagtttag ctagtccgct ttttgtcaat tgccaagacg tataggttcc
    10861 aatttcagta ggcgcagtta cttcaactcc cttttcattc atcgctttga aatcagttgg
    10921 attccatgtg atttgatcaa tactgagatc attgtttaaa agggatgttg attctgtttt
    10981 atcattaaag gcatatttaa cgatcggtac aacagaaaga ccatcatagt acttactgcc
    11041 atttgcattg attgatactg ttgcatttgt cttataatat aggatgactt cagaaatctg
    11101 ttttccattt gcgtccttta cgattacatt tccatttgta tctaaactag ctaaaacact
    11161 cattgctgat tggttctttg tttctatcgc tgaaacagct gtaaaggtat atccgttgat
    11221 agtaggcgta ttagtcgtca ggtcttgtgc agcacttccg taagtaagat tcattatttt
    11281 agaaggagca atcatctgtc caaaatagtc ttgatactta atagtgattg gtgtttgttt
    11341 gcctgtatag gtcaccgtat cgacgttact ttctagggct gtgaaagaac cgtttgtttg
    11401 tgcaaaagaa tagcccgtta ctgctgttgg agtgataacc actttgtcac ccacatggat
    11461 tccagataat gtagtcccgt acgttccgat ttttgctgct ccaccattga ctgtataaga
    11521 aaaagttcct gtccgattcg cattgacctg aaccgttgct gcttgatagg ttggaaaatt
    11581 tgaaacattt cccttaccat caacgatctg cccatttttg atcgagtacc ccgtgaatgg
    11641 aatatcattt gctaactgta taccgattga aaaagtactc atacctcctc cggcaggaag
    11701 ccctccccat gttgagggtg taaaagaata acttttatcc gcattgggtg taactgaatc
    11761 gatcgtattt ccagcggtag ccacccccat atagatactt tttgggaatg tgatagtagt
    11821 accatttact gtggagccaa taaacagatt atggatatct ggacggttat caataaaagc
    11881 gattgctttg gttacgcctt gtaacgcagt tttatccgca ctcatcgatc cgttaaccgc
    11941 aacaatgact ccatctttgg catatatcac tgtatatcca tctggtatgg tatgtccgtt
    12001 gaaattcgca gtggccgcaa cagtactaaa tgtctggctt ctacctgttt ctgaataagc
    12061 tttctcccct gctgcttttg ctgctgtgat ttctttttct gtcggatcaa tcagttgagt
    12121 cgaggatgtg gttgaggttg tctcgttgtt gctagactga ttggtgcttt ctatggactg
    12181 tatttcagaa tagggtggac tatttgtctc ctctgtcgtt tggttagcaa aatttgacgt
    12241 ttctgtataa acgtttacat aaatacttga taagctccct aagaaagtaa aaatcaagat
    12301 gatcgaaatc ataatgggat gtaagtattt tcttttagat acagctttga gtctagaaac
    12361 aaaatgtttt tgacatatac gttggatttt attttgagtt ttcttaatca ttttcatccc
    12421 tcctctcaat aaa
//
LOCUS       DACGEU010000082        12288 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.083, whole genome shotgun sequence.
ACCESSION   DACGEU010000082 DACGEU010000000
VERSION     DACGEU010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12288)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12288)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12288
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.083"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..191)
                     /locus_tag="IXR40_002198"
     CDS             complement(<1..191)
                     /locus_tag="IXR40_002198"
                     /inference="COORDINATES: protein motif:HMM:NF013540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4362028.1"
                     /translation="MKPNPVETGKRIKSIRSNFGMTMEQFADLIGNAQKGNINNWERG
                     FSLPNKERLIKIAELSNKT"
     gene            complement(205..1587)
                     /locus_tag="IXR40_002199"
     CDS             complement(205..1587)
                     /locus_tag="IXR40_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4362029.1"
                     /translation="MKPNLSLTSKRIRKIIESKGLTLEQFGDLIGDTPISSVNNWLRG
                     VSLPNKNRLLTIANIGNTSADWIKWGTLEEYIASYLIDSGYELYIKDFPEIPHKVFKD
                     IQEKYSDTFSLDKDYELLNPIIKFNIGGVTLNRIKFYIDSSKKTIKQISTETGINYTT
                     LTNYYRGERNPRNTETWNILADYFHVPVSYLMGLDETNVELKNLNIGDNIKSTRKSKK
                     MTQNDLAIKASISRSYLADVEGDRYNPSIETLDSIARALDVPIVALINDSSTDNIVEP
                     YESLTAENILLKQENEELKYEVESLRKRLYEIQQVVNQGAEKMIPNLKDVSKRIKYIR
                     KKLGMTMEQFGSHLSNSPKSTIATWESGRNIPSQKKLQLIAIVGETTTDWIKWGTLEE
                     YITSYLIGIGYELYIKDFPEIPHKVFKDIQEKYSDTFSLDKDYELLDSIIKNIFTKYY
                     SKEFEVNQIP"
     gene            complement(1636..2511)
                     /locus_tag="IXR40_002200"
     CDS             complement(1636..2511)
                     /locus_tag="IXR40_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4362030.1"
                     /translation="MKPNLIETGKRIKSIRSNLGMTMEQFAILTDSSNTSAVNNWERG
                     YNLPNKTKLKKIAILGNTTTDWIKWGTLEEYIASYLKDSGYELYIKDFPEIPHKVFND
                     IQERYSNTFSLNKDYELLNPIIKNIFTKYYSKDFEDYRDIEVKPDLGLTDDNKNIKMI
                     GQRIRKIRKKENITLEEFGKLFSPTADKAVISNWENGKNLPNSERIKKIAEIGGVSEL
                     YLMTGVDSSVAESMYFLSEVALDALERLSIEEVNRIIESFAGYLNVISKIDDPDKREI
                     SLNAICQLSLLDKMG"
     gene            2817..3005
                     /locus_tag="IXR40_002201"
     CDS             2817..3005
                     /locus_tag="IXR40_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HAQ4362031.1"
                     /translation="MPLTGKKMLKLAKKNGWKVVRITGSHHIVAKEGFPPVPIPVHSN
                     QDLKKGTEQKLLKDLGLK"
     gene            3051..3428
                     /locus_tag="IXR40_002202"
     CDS             3051..3428
                     /locus_tag="IXR40_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HicB family protein"
                     /protein_id="HAQ4362032.1"
                     /translation="MKKSYPVIFSAEENGYSVVFPDFAGATQGDNFEEAMSNAKEFLD
                     GILAYYIDEDISVPSPTDIHQLNNLGNNKIVSLIQSDPSPFIQKKTVRKNVTVPEWLV
                     ARGEKDKINFSKVLTDALLKIYE"
     gene            complement(3988..5160)
                     /locus_tag="IXR40_002203"
     CDS             complement(3988..5160)
                     /locus_tag="IXR40_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362033.1"
                     /translation="MTKKIEVYVDGSQEERDSFFGFFWKNSREYVKALNMVYKQLMFE
                     ELIENSIKELDHEYIKRELSLEERIDNLLSNEVIDQKKLDKTKRELSKLRIAKNKEAR
                     DVLTQAIGLKSQTRIRDIAKKLDFDYSDFIDSAKMKASKDFSNDFVGIVTGQRTPRIY
                     RNKNKYGLLPFRGRDIKIHKADKFYISLPKGFRFKVNLGRKPRKARDSALTLERIMDG
                     QYKLNQSNLIFEGKNLFLNLTISFEKDYHKLDFKEGAELTIKFTDLCSGKCLVNNQSV
                     IDFGDSKYISNFKNKIKAMKSREQSRGVFSKGGHGRKRKLDQDRWEAIKKRESNFVKT
                     YNNQCSAKIIQTAIRNKTQIICISEPDKNYGEWAYYQLKEQIINKGKRYGIEVKSE"
     gene            complement(5404..6372)
                     /locus_tag="IXR40_002204"
     CDS             complement(5404..6372)
                     /locus_tag="IXR40_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HAQ4362034.1"
                     /translation="MSLENEKPYYVVVGGVNGAGKSTIYQVQNLKRKELDTDRINADE
                     ILRSFGGNWKKQADINKSMREVLREIKGHFKEGKSFHHETTFGGNPYPDKMRLLKAKK
                     LGYESFLIYIGLDSPERAIERVKIRVAKGGHGVPEDLIRKRYEFSLRNLAELEKYFDN
                     VSIYDNSDEFSYIYVKENHTVVANNTQEYAWVPKAIQEKNAETPISKQIMMDISQEEM
                     NPKETLERIYSASDDFISDRFSKEAQVDDFYRNHKNEIKERILSISFSTGVSQDELVG
                     QDKRRNSCKLAYINSVGELLVKTDSELLSMELNRDRNIQKTDFEVE"
     gene            complement(6369..6566)
                     /locus_tag="IXR40_002205"
     CDS             complement(6369..6566)
                     /locus_tag="IXR40_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362035.1"
                     /translation="MRAMTEAVKELKKMYPDVLNMTVDDFHEALKNAESEEERTFYLT
                     LSSFVTRVDQKKVINQKDFKI"
     gene            complement(6577..6894)
                     /locus_tag="IXR40_002206"
     CDS             complement(6577..6894)
                     /locus_tag="IXR40_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362036.1"
                     /translation="MKDYASRKFIHLEPMKELVINGNEYNDYKSLFVKEQPKGGIRMK
                     NLPDFRFIEVNNLGIIEDYLDKLDEAIKQSIEKNGEDHILTVVLKDLKDRLEAEAEYF
                     NKD"
     gene            complement(6931..7149)
                     /locus_tag="IXR40_002207"
     CDS             complement(6931..7149)
                     /locus_tag="IXR40_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362037.1"
                     /translation="MVNKKETFKVGMEVQGVVIGSGELIEGEVISLLANVAVVKAIGK
                     APVVMKKCSMMCLDGLNNPITQRFENVI"
     gene            complement(7258..7449)
                     /locus_tag="IXR40_002208"
     CDS             complement(7258..7449)
                     /locus_tag="IXR40_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362038.1"
                     /translation="MEQTRMFWSDRMQDHLDCIYKTREQLNKLDTVRYYFTYFSENDE
                     QRWDIFHDGNYEEFFYTES"
     gene            complement(7611..7967)
                     /locus_tag="IXR40_002209"
     CDS             complement(7611..7967)
                     /locus_tag="IXR40_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362039.1"
                     /translation="MNDTIAILSDSLIDLDKTSTDYMIIEEQLKNKNPEFDIQEKSLR
                     IELPKFKQKKLITILFEIIERYGLTYYQIWTDKKDGQYTKGVSIEAVREDDQVSIKAV
                     QPLMGYNEELLNCLNV"
     gene            complement(7992..8996)
                     /locus_tag="IXR40_002210"
     CDS             complement(7992..8996)
                     /locus_tag="IXR40_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3991 domain-containing protein"
                     /protein_id="HAQ4362040.1"
                     /translation="MDLKKAKKVSIVDFCKQNGIGLKQDSREYYRLEDHDSCVISDRK
                     NLFKWNSKDLGGDIFDFIKAYYDCSFKEAKQKLEDSDYEVHSFNTKVKKAPYQYQKEN
                     EVPVSVAKSYLVNERRIDTALVEDFLSKGLIKQDKKGNVLFLWKKDQEIVGCTEQGTR
                     KFFHEGKQKDVTWKKIQENSKEYSGFNVTFGQPDKMYFFESEIDLMSYITQKPEKAEN
                     ATFVSMNGLKVGNVLHGVTEHYNKFKSLPSETVLCVDNDKAGRTFIETEFKEKGIGRE
                     GIGISEVKVDVPLREGFDWNDNLTRGKEAFKRFKLEDVSKIVNFTHKLSLNTPVYEME
                     "
     gene            complement(9033..9293)
                     /locus_tag="IXR40_002211"
     CDS             complement(9033..9293)
                     /locus_tag="IXR40_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362041.1"
                     /translation="MIEQENRNFLETQGEYRQINNSHFVICEDVQIAFKMALKYGKSI
                     RKKIIREKKSKKIGFWELSLRDGLNFIFCTEDYYEKYKCTLS"
     gene            complement(9302..10375)
                     /locus_tag="IXR40_002212"
     CDS             complement(9302..10375)
                     /locus_tag="IXR40_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362042.1"
                     /translation="MSNEQNYETGGTYRLFHGSMNKFDEFSLDHKGLNGTANGFGVYL
                     TPNKEMATMYAEQGSNGNNGFVYEVNVELEKPISMNERTITDEELSKVIDKLQESNDI
                     LNDYNDVSYYGEKVVKREVIASLSENENDVDLINDIGNTIGDHEATAKAFYDVGKYTH
                     IIAEEQLRQKDVVIVVLQPDKVKIETIHDLNEERNSLESSEDMTDKFVGHKVSEVPIR
                     EVVIKDFEQELETTNYYDKQAWQERIEYLENMEEPVSRLALDSDINEFYDSHKEEIET
                     KLTNLSEKLEIDKEELLGFPVDTSSTEYKKATSIMAYNGAMREIYNEIENDTFEIPPV
                     SEEMENKILKLTNFENTTKFEME"
     gene            complement(10383..12209)
                     /locus_tag="IXR40_002213"
     CDS             complement(10383..12209)
                     /locus_tag="IXR40_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HAQ4362043.1"
                     /translation="MAYKKGNWKPKTKEQKQKELDDLIKASNSKIEQYQSNPEDMIEF
                     AKFMSKIHNYSPLNLSLIDEGFEGAIAVASYDGWKKLGFQVKAKEKGIGIYAHAPVTV
                     FIDENGEEKTLKEATNEQKEKIKNGELRSKKIKHFKKGYVFDISQTNATEADLPKIFP
                     NRVWNFNIDGELSVSQLEKGVNHLAESMNISIKDMNESGRGEMGSARGEYIQYVDGRE
                     EIVLNSRNSRTQNLTTSIHELAHKKLHNKNEHGSSYSTPIKEFQAEMTSFIVCHNYGI
                     DTSDFTIPYIANWTKNNEKIDPKNFRQIMQEVRETSIDFISTIDKKVLEEQQTAFNAL
                     KNSFVPNENKEQIQQKSDLEFHNFYDSTINDPDRTIHGSYLEAMVDYYRGKYGENSIE
                     LTHSNYDVTAKIGENYVTYYSDTKQFDVCDVYGVVFENPSENKHDRLLLDRSPENCDY
                     VEKFVVESLKACENHELKNDTLKLSEPLRSVVINEAVYNLSENANNYYNEKCWQEEIE
                     NQTNINDVKELNSCMTAEDFYESHKQEIENTITDFESVSGTNLRDTIDNESYKEVASV
                     VAYKLVATKVKYEMDEGTFKIPENSNLEKPTVKTAERSFEME"
BASE COUNT         3581 a         2347 c         1540 g         4820 t
ORIGIN      
        1 atagttttgt tacttaattc agcaatttta attaatcttt ctttgttggg aagggagaat
       61 cctcgttccc aattgttaat atttcctttt tgagcatttc caattaaatc tgcaaattgt
      121 tccatagtca ttccaaaatt agaacgaatt gatttaattc ttttacctgt ttcaacagga
      181 tttggtttca tacaatcacc tctcttatgg aatttggttt acttcaaatt cttttgagta
      241 atattttgta aatatatttt ttattataga atccaataat tcatagtctt tatctaacga
      301 aaacgtatca ctatattttt cttgaatgtc tttaaagact ttgtgaggta tctctggaaa
      361 gtctttaata tatagctcat atcctatacc gataaggtat gaagttatat actcttctaa
      421 agttccccat ttaatccagt cagtggtggt ttctcctact atagcaatca gctgtaactt
      481 tttctgagaa ggtatatttc taccactttc ccaagtagca attgtacttt taggtgagtt
      541 gcttaaatga gaaccaaatt gctccatagt catacctaat ttttttctga tatatttgat
      601 tcttttactt acgtctttta gattgggaat cattttttca gctccttgat ttactacttg
      661 ttggatttca tacaatcttt ttcgtaagct ttctacctca tattttaatt cctcattttc
      721 ttgtttaaga aggatatttt cggctgtcaa actttcatac ggctctacta tattatcagt
      781 agaagaatcg ttgattaatg ctactatcgg aacgtccaat gctcgtgcta tggagtctaa
      841 agtttcaata ctagggttat atcgatctcc ttctacatcg gcaagataag agcgagagat
      901 actagctttg attgctaaat cattttgtgt cattttttta ctttttctag tgcttttaat
      961 gttatctccg atattaaggt ttttgagttc aacatttgtt tcgtctaatc ccatcaaata
     1021 acttacagga acatggaaat aatcagcaag gatattccat gtttcagtat ttctaggatt
     1081 tcgctcacca cggtaatagt tcgtaagagt tgtatagtta ataccagttt ctgtactaat
     1141 ttgtttaatg gtctttttac tggaatcaat ataaaatttt attctattca aagtaacgcc
     1201 ccctatatta aattttatta taggattcaa taactcatag tctttatcta gtgaaaacgt
     1261 atcactatat ttttcttgaa tgtctttaaa gactttgtga ggtatctctg gaaagtcttt
     1321 aatatatagc tcataacctg aatctataag gtatgaagct atgtattctt ccaaagttcc
     1381 ccatttaatc cagtctgcac tagtgtttcc aatatttgca attgttaaaa gcctattttt
     1441 attgggtaaa gacacgcctc taagccaatt attaacagaa cttattggtg tgtcgccaat
     1501 taaatcaccg aattgttcta atgtcagacc tttggattca ataatttttc taatacgttt
     1561 actagttaac gatagattag gtttcatagc taagcctcct cgtgagtaaa gtaatctttc
     1621 aatatttttt gtgaatcaac ccattttatc gagaagtgat agttgacaaa tagcattgag
     1681 agatatttct cgcttatctg gatcatcaat ttttgaaatc acattaagat aaccggcgaa
     1741 actttcaatt attctattga cttcctcaat tgacagacgt tccaaagcat ccaatgctac
     1801 ttcagataga aaatacattg attctgctac gcttgaatcg acacccgtca taagataaag
     1861 ttcagaaact ccgccaattt ctgcaatctt tttaattctt tctgagttag gaaggttttt
     1921 accattttcc cagttgctta taacagcttt atcagctgta ggagagaata gtttgccgaa
     1981 ttcttctaat gtaatattct ctttttttct tattttcctt atacgttgtc caatcatttt
     2041 aatatttttg ttgtcatcag tcagtcctaa atctggtttg acttctatgt ctcgataatc
     2101 ttcaaaatct tttgagtaat attttgtaaa tatatttttt attataggat tcaataactc
     2161 atagtcttta tttagcgaaa acgtattact atatctttct tgaatgtcat taaagacttt
     2221 gtgaggtatc tctgggaagt ctttaatata tagttcatac cctgaatctt taaggtatga
     2281 agctatgtat tcttccaaag ttccccattt aatccagtca gtagttgtat ttcctagtat
     2341 agctattttt tttagtttgg ttttattggg taagttgtaa ccacgttccc aattattaac
     2401 agcactcgta ttagaagaat cagttaaaat agcgaattgc tccattgtca ttcccaaatt
     2461 agaacgaatt gatttaattc ttttacctgt ttcaataaga tttggtttca tacaatcact
     2521 tctcttatgg aatttggatt catagtatct tattcgctct ttgagttcta agttctcttt
     2581 ctccaatttt tctatataat attcttgatc ctgtttcttg ttcaaaaaat gacctccaaa
     2641 tttcacattg tgttacaccc taatgttaca cctccaaacc ttattatact gtactttacc
     2701 atatgataca atagggtata ccctattgtg acacttacat tctactttta atgtaaaaac
     2761 tcttgacctt tatacgcata atgcgtataa taatatttgt aaggaggtag tcgcgaatgc
     2821 cacttaccgg taaaaaaatg ctcaaactag ccaagaaaaa tggttggaaa gtggtgagga
     2881 taactggcag ccatcatatt gtagccaaag aaggattccc acccgttcct attcctgttc
     2941 atagtaatca ggatttaaaa aaagggacag agcagaagtt actaaaggac ttagggctga
     3001 aatagcccag tcctttagtt cattggatta actcgaaagg agtggtggaa atgaaaaaaa
     3061 gttaccctgt aattttttct gctgaagaaa atggctactc agtagttttt cctgattttg
     3121 ctggagcaac acaaggagat aattttgaag aagctatgtc caatgctaaa gaatttcttg
     3181 atgggattct agcttactat attgatgaag atatttcagt tccttctcca acagatattc
     3241 atcaactaaa taatttgggc aataacaaaa ttgtttctct tattcaaagt gatccttctc
     3301 catttatcca aaaaaagacc gtacgcaaaa acgtcacagt cccagaatgg ttagtagcta
     3361 gaggggaaaa agataaaata aatttttcta aagttttgac agatgcgtta ctaaaaatat
     3421 acgagtaaac gtaaatatat taataacaat ttagttgcct aatgacatag atagcggaat
     3481 taaaagtaaa atagtactca tttattgcag gttcccttag aatcaataca ataaatgagt
     3541 actatttaga ctgtttaact actagtaaga tatagcgatc atcagtttca gggttatccc
     3601 ttggtgacca tagttttgcg tatttttcaa ctcgttgcca aatcaacgat tctatttttt
     3661 tatttctact taactccaaa acggagtacc ttctttttct tcgttagctc ctatttaaga
     3721 gccatgtcgt tttatataac tctaaaacag aaactactga tcaattcaat aaagccttat
     3781 ttgagaactg tgttgtttta catggtttta aaacctgatt tcccgcaaac ggtttatccg
     3841 taacatttga gaactgtgtt gttttacatg gttctaaaac ctcaacaata ttcgtccttc
     3901 cgtctggtta cacaacttga cagagctaac ccttcagtga gtgagtgtcc cctcactatt
     3961 tcgttgccaa atcaacgatt tcttattcta ctcactttta acttctattc catatctttt
     4021 ccctttattt attatttgtt ctttcaactg ataataagcc cattccccat aatttttatc
     4081 tggttcagaa atacagatta tttgcgtctt attgcggata gctgtttgaa taatttttgc
     4141 cgaacattga ttattatagg ttttaacaaa attgctttct cttttcttta tggcttccca
     4201 tctatcttga tctaattttc tttttcgacc atgaccgcct ttagaaaaaa ctcctcggct
     4261 ttgctccctt gatttcattg ctttaatttt atttttgaag ttacttatat atttgctgtc
     4321 accaaaatca atcacagatt gattgttaac taaacattta ccgctacaca aatcagtaaa
     4381 ctttatggtt aattcagctc cttctttgaa atctagctta tgataatctt tttcaaaaga
     4441 aattgttaaa ttcaaaaata aatttttccc ctcaaagatt agattactct ggtttaactt
     4501 gtattgaccg tccataatgc gttctaaagt taaagcgcta tctctggctt ttcttggttt
     4561 tctacctaaa tttactttaa acctaaatcc tttaggtaaa gagatataaa acttgtcagc
     4621 tttgtgaatc ttaatatccc gacctctgaa cggtaacaat ccatatttat ttttatttct
     4681 atagattcta ggtgttcttt gcccagtaac aattccaaca aaatcattgc taaaatcctt
     4741 actagctttc attttagctg aatctataaa atccgaataa tcaaagtcca atttttttgc
     4801 tatatcacgt attctggttt gactttttaa acctatagct tgtgtcaaaa cgtctctggc
     4861 ttctttgttt ttcgcaattc gtagtttaga taattccctt ttcgttttat ctaatttctt
     4921 ttgatcgatc acttcattac ttagtaaatt atcaattcgc tcttcaagac ttagctctct
     4981 tttaatatac tcatgatcca attcttttat agaattttcg atcaattctt caaacatcag
     5041 ctgtttatat accatattca gcgcttttac atattctcta ctatttttcc aaaaaaaacc
     5101 aaaaaacgaa tctctttcct cttgtgatcc atcaacatat acttctattt ttttagtcat
     5161 agttattatt gtcaatttta gcacctcatt attatatatc tggtatataa taatagtaac
     5221 atatttccta gactataatc aatgatcaat tgtctacttg tagtaattat attaaaaaca
     5281 aaaactaaaa ataatatatt attccttctg actacatata gtcactttat ccaaaaaata
     5341 agaagtgctt tcgcactcct tattaaattt atttactatt aattgattca gctacaactt
     5401 cttttattca acttcaaaat cagttttttg gatatttcta tctctattta attccatact
     5461 taatagctca ctatcagttt ttactaaaag ctcacctaca ctattaatat atgccaattt
     5521 acaagaattt cttcttttat cttgacctac taattcatct tgagataccc ctgtagaaaa
     5581 actaattgat agaatccgtt ccttgatttc atttttatgg ttcctataaa aatcatcgac
     5641 ttgcgcttct tttgaaaacc gatcactaat aaaatcatca cttgctgaat atattctttc
     5701 aagggtttct tttggattca tctcttcttg agatatatcc atcataattt gtttgcttat
     5761 aggagtttca gcatttttct cttgaatagc tttgggaacc caagcatatt cttgcgtatt
     5821 attggctaca actgtatgat tttctttaac ataaatataa gaaaactcat ctgaattatc
     5881 atagatactt acattatcaa aatatttctc taactctgct aagtttctta aagaaaattc
     5941 gtaccttttt cttattaaat cttcaggtac accgtggcca cctttagcaa cacggatttt
     6001 aaccctttca atcgctcttt ctggtgaatc tagtcctata tagattaaaa acgattcata
     6061 acctaatttt ttagccttta gaagtctcat tttatcggga tatggattac caccaaaagt
     6121 cgtttcatgg tgaaaagatt ttccttcttt aaaatgacct ttgatctctc ttagaacttc
     6181 acgcatactt ttgtttatgt ctgcttgttt tttccaattt ccgccaaaac ttctcaaaat
     6241 ttcatctgca ttaattctat cagtatcaag ttcttttctt tttaaatttt gaacttgata
     6301 aatagtagac ttaccggcgc cgttaacgcc cccaacaact acataatacg gtttttcatt
     6361 ttctaaactc atattttaaa gtctttctga ttaattactt ttttttgatc tactcgtgtc
     6421 acaaaactag aaagtgtaag gtagaaagtc ctttcttcct cactttctgc attttttaag
     6481 gcttcatgaa aatcatctac agtcatattc aaaacatcag gatacatttt ctttaattct
     6541 tttacagcct ctgtcatagc tctcattccc ttcttattag tctttattaa agtactctgc
     6601 ttcagcttct agtctatctt tcaagtcttt taaaacaacc gtaagtatat gatcttcacc
     6661 atttttttca attgattgct ttatcgcttc atctaactta tctaaatagt cttctataat
     6721 tcctaaattg tttacttcga taaatcggaa gtccggtaaa tttttcatcc gaataccgcc
     6781 tttaggctgt tcctttacaa ataaagattt gtaatcatta tattcattcc cattaataac
     6841 caattctttc ataggctcta agtggataaa tttacgtgaa gcatagtctt tcataataat
     6901 ctctcccagt agaaaatctt cttttttcta ttatatcacg ttctcaaagc gttgagttat
     6961 tggattgttt aaaccatcaa gacacatcat gctgcatttt ttcatcacta ccggtgcttt
     7021 tccgattgct ttaactaccg ctacattagc taacaaacta attacttctc cctcgataag
     7081 ctctccgctc ccaataacaa cgccctgtac ttccatacct actttaaacg tttctttttt
     7141 atttaccatt attccgctct ccttccatga ctacttgtag tcatttggat attttttagg
     7201 ggaacggttt tccgttccct ttcatcaaat agaatccttc atcatttcaa caaataatta
     7261 actttcagtg taaaaaaatt cttcgtaatt accatcatga aaaatatccc atctttgttc
     7321 gtcattctca ctgaagtagg taaaataata tctgacagta tctaacttat ttaattgctc
     7381 tctggttttg taaatacaat ccaagtgatc ttgcattcga tctgaccaaa acattcttgt
     7441 ctgctccatc tattatctct cctttttatt aaatcaaggg tttgagtctt tgactacttg
     7501 tagtctatgg ctatatcata caggaatgac tacttgtagt caatggtttt ctttagttta
     7561 attaactgtc tattcgtagc caaataatgt aaaaaaacgc ctagtttaca ctagacgttt
     7621 aaacaattca ataattcttc gttatacccc attaagggtt gaactgcttt aatacttact
     7681 tgatcgtctt ctctaacggc ttctatgctt accccttttg tatattggcc atctttctta
     7741 tccgtccaaa tttgataata agtaagccca tatcgttcaa taatctcaaa gagaatagtt
     7801 attaattttt tttgtttaaa ttttggtaat tcaatacgca atgatttttc ttgaatatcg
     7861 aactctggat ttttattttt aagttgttct tcaataatca tatagtctgt agacgtctta
     7921 tctaaatcaa ttaatgaatc tgataagatt gctattgtat cgttcataac acatcaacta
     7981 ctttcttctt tttattccat ttcatataca ggagtattaa gagataattt atgtgtgaag
     8041 ttcacgattt ttgatacatc ttctaacttg aagcgtttaa aagcttcttt tcctcttgtt
     8101 aaattatcat tccaatcaaa tccctctcgc aaaggtacat cgacttttac ttcactgatt
     8161 cctatccctt ctcttccaat tcctttttct ttaaattcag tttcaataaa agtacgtccg
     8221 gctttatcat tatcaacaca aaggactgtt tctgaaggca atgatttaaa cttattataa
     8281 tgctctgtaa ccccatgcaa tacattacct acctttaatc cattcatgct aacaaacgta
     8341 gcattttcgg ctttttctgg cttttgtgta atgtacgaca tcaaatctat ttcactttca
     8401 aaaaaataca ttttatctgg ttgaccaaaa gttacgttaa atcctgaata ctctttagag
     8461 ttttcttgta tttttttcca tgtaacatcc ttttgtttgc cttcatgaaa aaattttcta
     8521 gttccttgtt ccgtacaccc aacgatttct tgatcttttt tccataagaa caaaacattt
     8581 ccttttttat cttgtttaat tagtccttta gataaaaaat cttccactaa agctgtatcg
     8641 attcttctct catttactaa ataagacttt gcaacagata ccggcacttc attttctttc
     8701 tgatattggt acggagcttt tttcactttt gtattgaacg aatgaacttc ataatcacta
     8761 tcttcaagtt tctgttttgc ttctttaaat gaacaatcgt agtaggcttt gataaaatca
     8821 aaaatatctc cccctaaatc ctttgagttc catttaaaaa ggtttttacg atcactgatt
     8881 acacaagaat catgatcttc taatctatag tattcccttg aatcttgctt taaacctatc
     8941 ccattttgtt tgcaaaaatc aacgatactt actttttttg cctttttcaa atccaaacaa
     9001 aaaccccctt tactagacca tcactagtaa aattacgata aggtacactt gtatttttca
     9061 taataatcct ctgtacagaa aataaagttt agcccatccc taagagataa ctcccaaaag
     9121 cctatcttct tgctcttttt ttctctaatt atcttttttc taatactttt tccgtacttc
     9181 aaagccattt taaaagcgat ttgtacatct tcacaaatta caaaatgact attattaatt
     9241 tgacgatatt caccttgcgt ttctaaaaaa tttctatttt cttgttctat cattcattta
     9301 tctactccat ttcaaatttt gttgtatttt caaaattagt caatttcaaa atcttattct
     9361 ccatttcttc agaaacaggt ggtatttcaa acgtatcatt ttcaatttca ttataaattt
     9421 ctctcattgc accgttgtaa gccatgatag acgtagcttt tttgtattcc gtagaagaag
     9481 tatctactgg aaaacctagc agttcttctt tatcgatctc taacttttcg gataaatttg
     9541 tcaatttcgt ttcaatttct tctttatgac tatcataaaa ttcattaata tcactatcta
     9601 atgctaatct ggaaactggt tcttccatgt tttctaagta ttcaatgcgc tcttgccaag
     9661 cttgtttgtc ataataatta gttgtttcta gctcttgctc aaaatctttt atcacaactt
     9721 ctcgaatggg aacttccgaa accttatgcc caacaaattt atctgtcatg tcctcactac
     9781 tttctaagct attccgttcc tcgtttaaat cgtgaatagt ttcaatcttt actttatcag
     9841 gctgtaacac tacgataact acatcctttt gtcttaactg ttcttccgca ataatatgtg
     9901 tatatttccc aacgtcataa aatgccttag cagtagcttc atgatctcca attgtatttc
     9961 caatgtcgtt aatcaaatct acgtcatttt cattctcact aagagaagca atcacttctc
    10021 tttttacaac tttttctccg taataactaa catcattgta atcatttaaa atatcattac
    10081 tttcttgtaa tttatctatt actttagaaa gctcttcatc agtaatagtg cgttcattca
    10141 tagaaatcgg cttctctaat tcaacattta cttcatatac gaaaccatta tttccgttac
    10201 taccctgttc agcgtacatt gtagccattt ctttattagg tgttaagtac acaccaaatc
    10261 cattagctgt tccgtttaaa cctttatgat ctaaactaaa ttcatcaaat ttattcatac
    10321 ttccatgaaa caggcgataa gttccgcctg tttcataatt ttgttcatta ctcataattt
    10381 tttcactcca tttcaaaaga acgttctgct gtttttacag tcggcttttc caagttagaa
    10441 ttttctggta tcttgaaagt tccttcatcc atttcatatt ttactttagt tgcaaccagt
    10501 ttataagcta ccactgaagc cacctcttta tatgactcat tgtctattgt atctcttaaa
    10561 tttgttcctg acacagattc aaaatctgta atcgtatttt cgatttcttg tttatgagat
    10621 tcgtaaaaat cttccgcagt catacaagag tttaattctt ttacatcatt aatatttgtt
    10681 tggttttcaa tttcttcttg ccagcatttt tcattatagt aattgttagc attttcagat
    10741 agattataaa ccgcttcatt tataacaact gatcttagcg gttcgcttaa ttttaacgta
    10801 tcatttttta gttcatgatt ctcgcaagct ttcaaacttt ctacaacaaa cttttcaaca
    10861 taatcacaat tttcaggtga tcgatctaat agtaaacgat catgtttatt ttcacttgga
    10921 ttctcaaaaa ctacaccata aacatcacat acatcaaatt gtttcgtatc tgaataatat
    10981 gtcacatagt tttctcctat tttagctgta acatcataat tgctatgagt aagctcaata
    11041 gaattttctc catactttcc tctataataa tccaccatcg cttctaaata actaccgtgg
    11101 attgttctat ccggatcgtt gattgtacta tcgtagaaat tatgaaattc taaatctgat
    11161 ttttgttgta tctgctcttt attctcatta ggaacaaagg aattttttag tgcattaaat
    11221 gctgtttgct gttcttccaa gactttctta tcaatcgtac ttataaagtc aatagacgtt
    11281 tctctaactt cttgcattat ctgtctaaag ttttttggat caattttttc attattttta
    11341 gtccaatttg caatataagg aatagtaaag tctgacgtat caataccgta attgtgacaa
    11401 acaataaatg aagtcatttc cgcttgaaac tctttaatcg gtgttgagta ggaagaaccg
    11461 tgttcattct tattgtgaag ctttttgtga gccaattcgt gaatactggt agtaagattt
    11521 tgtgttctgc tatttcttga atttaataca atttcttccc taccatcaac atattgaata
    11581 tattcacctc tagcgcttcc catttcacct ctaccagact cgttcatatc ttttatagat
    11641 atattcatag attcggccaa atgatttaca cctttttcta attgactaac acttaattca
    11701 ccatcaatat taaaattcca taccctgtta ggaaatattt ttggcaaatc agcttcagtt
    11761 gcattagttt gggaaatatc aaatacgtaa cccttcttaa aatgcttgat ctttttgctt
    11821 cttaattctc catttttgat tttttctttt tgctcgtttg tcgcttcttt taacgtcttt
    11881 tcctcaccat tttcatcaat aaaaaccgtt accggagcat gcgcataaat gcctatccct
    11941 ttttctttcg ctttaacttg aaatcctagt tttttccaac catcataact tgctacagca
    12001 attgctcctt caaatccctc atcgatcaac gataggttta aaggactgta attgtgtatt
    12061 ttagacatga acttggcaaa ctcgatcata tcttcagggt tagactgata ttgctcgatt
    12121 ttgctgttgg aagccttaat taaatcgtct agctcttttt gtttttgctc tttcgttttc
    12181 ggcttccagt ttcctttttt ataggccatc ttctatctcc tttctttttt aggtaagtta
    12241 aattacctaa ttaaattata ccagatatat aaaaactctt ctatctaa
//
LOCUS       DACGEU010000083        12171 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.084, whole genome shotgun sequence.
ACCESSION   DACGEU010000083 DACGEU010000000
VERSION     DACGEU010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12171)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12171)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12171
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.084"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            592..1920
                     /locus_tag="IXR40_002214"
     CDS             592..1920
                     /locus_tag="IXR40_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HAQ4362044.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            2122..2955
                     /locus_tag="IXR40_002215"
     CDS             2122..2955
                     /locus_tag="IXR40_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HAQ4362045.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            2971..3708
                     /locus_tag="IXR40_002216"
     CDS             2971..3708
                     /locus_tag="IXR40_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HAQ4362046.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(3863..4831)
                     /locus_tag="IXR40_002217"
     CDS             complement(3863..4831)
                     /locus_tag="IXR40_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HAQ4362047.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            5063..5896
                     /locus_tag="IXR40_002218"
     CDS             5063..5896
                     /locus_tag="IXR40_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HAQ4362048.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            5930..6769
                     /locus_tag="IXR40_002219"
     CDS             5930..6769
                     /locus_tag="IXR40_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAQ4362049.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            6795..7355
                     /locus_tag="IXR40_002220"
     CDS             6795..7355
                     /locus_tag="IXR40_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HAQ4362050.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            7554..9275
                     /locus_tag="IXR40_002221"
     CDS             7554..9275
                     /locus_tag="IXR40_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HAQ4362051.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            9440..10582
                     /locus_tag="IXR40_002222"
     CDS             9440..10582
                     /locus_tag="IXR40_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HAQ4362052.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            10598..11809
                     /gene="thiI"
                     /locus_tag="IXR40_002223"
     CDS             10598..11809
                     /gene="thiI"
                     /locus_tag="IXR40_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HAQ4362053.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
BASE COUNT         4148 a         2042 c         2527 g         3454 t
ORIGIN      
        1 aaagcttatg caaagaaaaa gaaatccaat cacttgggtt tctttttctt ttattattat
       61 gatgaatcaa gctttctgtt tttgtcacgt atgttgtaat ctttacgaaa gagtagagtt
      121 ggctactcat aatcaaccat acttcccatc atcgctaaat acgaaataaa tcagcattcc
      181 tacaccaatc aaagcacaag ctgcaccaag aaaagggatg acattcccaa agttatctgt
      241 attcataagt atgccaccac ccacaaacaa aaagccgcca gcaatcaggt ttttcatttt
      301 attcatctcc tttcttacgt tatagtattt ccttctttca atgagtattt tgaaagctat
      361 cttattgtat gatgttcttc taggcctctt ctttattata caggccattt tcgttatctc
      421 atagaaatat tcctttttat ctgaaaacta ttgtataccg tatgacattt ttcttcatga
      481 agttgtaagt atattctcat tcaaatgaaa atttcatcat agaagagatt gtatttctaa
      541 attcttaaga gtaaaatacg aagtataact tggatttgga aggatgattg gatgaaagct
      601 attacgcctg atatgacaac aaaatttaac aaacagtttc aagcaaatat caaacagcag
      661 gcattgcagc gggcagttgt gaagaacgga attactgctt ctgctgaaaa tgtttcagca
      721 catgtggaga atacaccggt attttctata gatttggcta cggggaaagt ggctaatcaa
      781 atgcaatcgg ggcgttgctg gatgtttgct gcactgaaca cattccgtca taagatgctg
      841 aatcaattcc atttaaaaga gtttgaatta tcacaaaatt acactttttt ctgggataaa
      901 tatgaaaagg caaattattt ctatgaaaac atcattgcaa caggaaaaga ggcaatcgat
      961 agccggaaag tagctttctt actcgctact cctcaacaag atggcggcca atgggatatg
     1021 atcgtttcat tattccaaaa atatggcgtt gtgcctaaat cggtgatgcc ggaaagtgcg
     1081 aatagttcaa attctcgaga tttgaataac tacttgaaca aattactgcg taaagatgca
     1141 gtagtgttac ggaaaatggt tgctcaagga gaaacattag acgctattga agaaaagaaa
     1201 gaagaaatgc tagaaagcat ttataacttc ttagctatct cattaggaac acctccaaaa
     1261 gaattcgatt ttgagtaccg cgatgaagaa aagaactatc atcttgaccg aggactgaca
     1321 ccacaaattt tttatgataa atacatcggt gtaaaattag atgattatgt tagcgtgatc
     1381 aatgcaccaa caaaagacaa accattcaat cgttcttata cagtagagat gctaggaaat
     1441 gtcgttggcg ggaaagaagt caaatatctg aatgttgata tggaaacttt caaaaaatta
     1501 gcgattgctc agcttgaaga aggagaatct gtttggtttg gttgtgatgt aggtcaatct
     1561 tctactagaa ctagtggcat catggcctta gatgcttatt caatggatga tctatttgat
     1621 acggatttta caatgactaa agctgaacgt ttagattttg gagaaagtct gatgacccat
     1681 gcgatggtat tgaccggtgt tgacttagta gacgggcaat caacaaaatg gaaagtcgaa
     1741 aatagctggg gcgaaaaagt tggaaagaat ggcttctttg ttatgagtga tgcctggatg
     1801 gacgaatata cgtaccaaat cgttgtaaga aaagatttat tgacgaaaga gcaattaaat
     1861 gcgttcaatg aagaaccaat tgttctatct ccgtgggatc caatgggtgc tttagcatag
     1921 acgagtattt caatgaagag tatgtagtaa agataaaaag agctggctta agccagctct
     1981 ttttatcttt aaagtccatt ccctgttttt tatggtccct gtgctataat tctaaataaa
     2041 ggataaggat tggaaataat ccttttatca ttaaaaatat gatgacgaag tagaataaaa
     2101 ttgggagtag gggggaaagt catggatatc caaactgttt tatctgatct gaaattaaat
     2161 ggtaaagtga ttccagttgt tggtggcgat gttaatcaga cctatcgtat aaaaaccgaa
     2221 catcgtgctt attttttaaa aatccatccg aatgtaaaaa aaggattttt tgaagcagaa
     2281 gtagacggat taaaagaact gtcagcattc gtacgtgtac cggatacgta tatgctaggt
     2341 gaaacaagtg aaggcgctta tttgttaatg gaatggatcg agccgggaaa aggggatcaa
     2401 cgagatcttg ctgcagcttt agctaatctc catcagcaaa cagcgccaca atttggtttt
     2461 cgtaaagata actatttggg tacacttgtt cagaaaaatt cttttgaaga agattggtgg
     2521 acttttttct ttaaagatcg gcttgaatcc cagatttctt tggcagaaga aacgaatcga
     2581 tggaatgtac agcgtcaaga aaagtatctg cgatttaaag aacgtgtatt gaaatcggtt
     2641 gaaccaaaaa agatcactcc acgcctcttg cacggagacc tgtggagtgg taatgtgttc
     2701 tttgaccagc aagggcatcc agtttttgtc gacccagctg tttcttatgg gaatcgggaa
     2761 caagatattg caatgagcca gttattcggt ggtttccgac cggaattttt agatgcttat
     2821 caaactatat ttccattaga aaagggatgg aaagaccgac tgccgattta ccagttatat
     2881 tatcttttgg cacatttgaa tatgtttgga gaaagttacg gttcccaagt agatcaatta
     2941 ctagaaaatt tttaagagga gggcgtgttt ttggcaaaaa aatataccaa aaagcatgaa
     3001 gtttcatatt atgagtgtga catcaaccaa acgatgacat ttccttcgat gttaggagta
     3061 gttatcaaaa cgtctgaaga tcaaagcgac cagttgggaa gaggcagtga attcgtcaat
     3121 agctttggac ttacttgggt catcacgaat tattccatgg agattaatcg tctccctaga
     3181 gtcggtgaag taatctcagt aacgactcaa gccatggagt acaataagtt tttctgttat
     3241 cggaacttct ggatccatga tgaagatggg aaagaattag tcaaaataga atctgttttc
     3301 gtattgatgg attttgtgaa tcgaaaaatg agcagtgtta atgaagagat cattgctcct
     3361 tttgagagtg agaagatcaa gaaaatcaag cgtcaggaaa aaattgaaaa gattgattcg
     3421 ggcttcatgt tgccatatcg tgttcgtttt tatgatatcg atagtaatca gcatgttaat
     3481 aatgcgatgt attttaattg gatcattgac gtattaggat atgacttttt gactacgcat
     3541 gttccagaaa aagtaattat tcgatttgat aaagaagtag agtacgggaa tgagatcgaa
     3601 agccattttg aacaaatccc tatcgaaaat ggtgtcaaaa caaaacatga aatccgaatg
     3661 caagaacagc tgtattgtga agcaaatatt atatggaaaa ataaataaaa aagaggttgt
     3721 gacagaaggg ggcaacttca agaaataaga agaaatttac gaaaattgtt tctcaaattt
     3781 ttgtaaattt tcgacttagt tttcgaagaa gctatttttg tcacagcctc tctttttaag
     3841 tttagctatt agataatgat gtttagtttt ggataaacga aatcaattct tcacccgaca
     3901 aaccatagtt tacagcaatc aatagtttta aacgtgcttt ttgactatta atactgttac
     3961 agaaaataat ccccattttt tctagttctt ttcccccgcc ttcataatca taaacaggct
     4021 ctgcgattcc attgaaacaa cgagaaacaa gtactacagg gattttttgg acaagaagct
     4081 tttccaaagc agctaaggct tgtggaggga gattccccgc acctaaagct tcgattacca
     4141 aaccgtctac tttcgtatgg gcgatggctt ccaataagtc cccttgcatc ccagcatatg
     4201 ctttaacgat cgggatagtc ccatctacag cggaaatgtc cagtcgcttt gtttctaaaa
     4261 gttcctgcaa gaataaaatt cgattcttag ttactaagcc gatgggaccc aatgtaggtg
     4321 ttcggaaagt agcaacattt gtggtatggg tctttgtcac gtagcgtgca gaatggatct
     4381 catcgttcat gaccaccaaa acccccttat ctagcgcttc ttcacaactt gcgacacgaa
     4441 tcgcactttc aaaattataa aggccgtcac ttccaagttc attacttgaa cgcattgccc
     4501 cagtcaaaac aattggtaat ttgttgccaa tcgttgtatc aagaaaaaaa gcagtttctt
     4561 ctaatgtatc tgtaccgtgt gtgatcacca ctccggatat acctgatgca taagcggaca
     4621 agatacgttc ttttaatacc aacatgtgag aaggcatgat gtgtggtgag ggaagattga
     4681 agatatcttc aactaataat tctacatgct tggggattgt gatttctgca tctaataatg
     4741 ggtttgccac atcaggacta acaccgcccg tgagcatgtt ttctttcatg gcgatcgttc
     4801 cgccggtgtg tagtacaagt atttttttca ttttacagac ttccttacga ataattttgc
     4861 atagccgtta aatcttattg tatactatat aaaagagttt tgctatcagt gaagaataac
     4921 gaatagccta acttatcata aaaaagctga ccttattaaa atggaaaaga ctcaaccttg
     4981 acctcctaat acaatggagt atctggttga gtttctttta caagaaagca gccaaggaaa
     5041 tcaatcacga aggtggccgg aaatgatcag aatcggatta acatcgttta aagaacatga
     5101 caaattaact ggtaaaaaga ataacactct ttatgaatat gcagggtttc tacccttagt
     5161 ggaattagat actgcctatt atggaattcc ccgaaagtcc tcagttgaga attggataag
     5221 tgaagtacct gaatcatttc gctttgtagt caaagtctat caaggaatca gcggtcaagg
     5281 agactggaag ccttattatc agaccgaaga agagatgatt gcgcattttt tagatgttat
     5341 gtcgccaatg gtagatgctg gaaagatgtt ttgcttttta gtccaattcc cctcatcatt
     5401 caaatgtacg aaagaaaatg tccagtactt gcgcaaactt agaaagtggt ttgagggtta
     5461 tcctgtttct atagaattgc gggattattc ttggtacagc gatgaatttc ttgaacgtac
     5521 aagaaacttt atgtctagag ccgctttttc tttagccatc atcgatgagc cacagttgct
     5581 gaatacaacg attccttttg atccatttgt caccaatccg aactttgctc tttttcgatt
     5641 ccatggtagg aatgcgcaag gatggcaagc aaatgataaa gagtggcgta aaaaaagaac
     5701 gttatatcgt tattcagaaa aagaactgca agaactagca catgaagtca aagtagttga
     5761 ttctaagaca aaagaggtag gtgtgatttt taataataat tctggtggtg atgcggctga
     5821 aaatgcatta gcactgcaaa aaatattaaa tatcaagcca gatggactca atccaaccca
     5881 aatggatctg ttttaagggc ttattttatt caagaaaggg gcgaagtcta tgatcaaagc
     5941 tatttttttt gatattgacg gaacattggt caccaatcgt tcaaaagcgt tggaatcaac
     6001 aaaacaagca attgaatatg ctcggaaaaa cggcatttta tgcggtgtag caacggggcg
     6061 cagcccagta aagatcaaag aaatcattga tgaattggaa ttagatatgt atgtcgtgta
     6121 taatggtcaa ctggttttta ctgcagatcg cacgattatc gaccaccctt ttgaacaaaa
     6181 agtattggaa catattgttg aatttgcaga tgagaaccat cgacaaatcg tttttggtgc
     6241 gagaaatcgg ttagatggat caacgacgat gctattagga caatcgattt ttatcaagcg
     6301 actagtcagc tttttaccgc gtaaattccc ggtacgtctg atgaaaaaaa tcctccaggt
     6361 ttttagccct caccgacaaa aggatcgtta tgaaacgtta gagatattaa aagaaccaat
     6421 ttatcaatgt atattgctca gtccggagtc agaacagaaa aagttagaac atcgctttcc
     6481 cgagtgtacg tttcagcgtt caaatacgta tactgtagat atcatcccaa aaggtggttc
     6541 aaaattacta ggcatccaag ctttcgcaaa tgctgtcgaa attgaaatgg aagaaattat
     6601 ggcattcggc gatcattaca atgatatcga gatgctgaaa ggtgtaggaa ttggagtggc
     6661 catggggaat gctcagatcg aagtaaaaca tgctgcagac tttgtgactc aatcaaatga
     6721 agaagatggg atatacgaag gactgaaaca cttcggtctg atttattagt caatgaaaga
     6781 aggaaaaaat cagtatggaa gcagagacac cttttcaaaa agtagaaaca ttccacaaaa
     6841 cttttgatcc aagaagacca gagataccca cggcttttac agaaaatgaa gctcatacac
     6901 gtgctgcgtt caaaatagaa gaacttgttg aatttgttgc agctacttca cctaataaag
     6961 aacaactgca tgaagctgtt atgctgctgc acgaagcatt agataaagca gaagaaaaaa
     7021 tacttggtaa aacacagtgg ggaagtgatc cgctggttga acaagtagat gcactgacag
     7081 atatccttta ctttacttat ggttcttttt cattactagg aatagtgcct gatcgaatat
     7141 tcgaaatcgt ccatcaggca aatatgggga aattatttcc agatggaaaa cctcattatg
     7201 accctgtaac aaataaagtg ttgaaacctg aaaactggca gatggaatat gctccagaac
     7261 ctaaaatcgc ggcagaaatc caacgtcaga ttcaagaagc gattgctaag aagaaatccg
     7321 ctgatatagg catgtgcaca aatgaaaaag agtgatcaga gtttcactat ttttgttatc
     7381 tttatacgat ggaaaaacaa aagattttcg tttaagttag tgaatgcatg aaaatagtat
     7441 gctataatct agaatagatg tcttttgcac gagagacgta ttatttggat ttatgccaag
     7501 cagaacgcca tctgttgcat aaaagatgca tactgaaaac ggaggaacca taaatgggaa
     7561 ataatgttat catcggaatc gtcattgcaa tcattatagt cgccattgtc gtctttttgg
     7621 ttagttactt gatgaagaaa aaaaaccaag atcgattgga tgccttagaa aaacgcaagg
     7681 aagaattatt tgacttgcca gtgattgaag aagtcgatga tgttaaaaaa atgcatctgg
     7741 ttgggcaaag ccaaaatacc tttcgtgaat ggagtcaaaa atggaatgac atatctactt
     7801 cctcgttcgc tgaactagaa agtcaaattt tcgaagtgga aaacctcaat gaaagttttc
     7861 ggttcttaaa aggaaaaaaa gcagttgttg aagcagaagc tacaatggac caaatggaga
     7921 aacaagtgac ggaaatccgt gaaggtctaa aggaattgcg ggaaacggaa gaacgcaact
     7981 cactagctgt tcagcaggca cttgacgtct atgaagaact gaaagaaaaa gtcagagaag
     8041 acgagcatga atacggacca gctctttttg aattgcaaaa acagatcaaa gtgatcgaaa
     8101 aagaatttac gcagtttgtg actttaaaca cttctggaga ccctgttgaa gcccgcgagg
     8161 ttttggataa agcagaaaaa catacgtatg aagtggaagc tctgatgaaa aaaattccac
     8221 cgctgtatga ggagctccat accactttcc ctgaacaact tgaagaaatc agtgatactt
     8281 acgagaaatt gatggaagaa caatatgtat tcccagaaga agatcttgct gaagatatcg
     8341 caaaagtaag tcgaagaatt gaaaattcat tagccaatct tgaaaaaaca gaagttgaaa
     8401 cggtcgaatt tgaaaaccgt gaaacagctg atttgattga ttcgttatat gatatcttag
     8461 aacgggaaat ggaagctcag agatatgtaa aaactaacca atcaacgatt gcagagtata
     8521 tcaaacatac aacaaagaat aaccgtcaat tattgattga gctggatcac acatctcaaa
     8581 gctatacatt gaaccacaat gaaattggcc gtgtacgagg tttccaaacc gaagtggaag
     8641 aaatggaacg tcaaaatgaa cagatgattc cacagatccg tcaacacgaa attccttatt
     8701 cagaagtgcg cacgttctat aaaacagtct tcaaagtctt agaagatatc gaaaagcaac
     8761 aagtagagat cgacgactca ttacatgaat tgagaaaagg cgaaaaagaa gcgcaagaaa
     8821 agatcgatac attcgaattc aaattgcgca gtttgaaacg ttttgtagaa aaacaacgtt
     8881 tgcctggctt gccgaatgat tacctagaat tcttttttgt tgctactgac cgtattgaag
     8941 aactaagtgt tgtcttgaat aaaattcgag taaacatgga agaggtcaat cgtttagttg
     9001 ctctatgtga agaagatcta gaattattag ataagaagac acatgattta gtagatgcag
     9061 cagcattaac ggagcaaatg ctccaatatg caaatcgtta tcgtcataca cacgaagaag
     9121 tgagagaagc aattgataaa agctactatt tattcaataa agaatatcac tatcaagaag
     9181 cattagacga aatcggtaca gcattagagc gagtagaacc tggtgctttc aaacgcatcg
     9241 aagattttta ttttaatcat ccagacttag tataaagcaa aaaagttagt aaaccagcaa
     9301 gagcaagacg gattattgtc ttgttcttgt ctttttttgt atatttgaaa attgaaacaa
     9361 gtgaaaattt cacctgctct tgaaagcacc ttggacaacc gttataatag aaaagaattt
     9421 caaaaaagag gggtttctta tgatatattt tgataacagt gcaacaaccc caatctttcc
     9481 gcaaagctta gatgcatatg taaaaaccag tcagcggatt attgggaatc catcaagctt
     9541 gcatgattta ggcaatcaag ctaaccggtt gttgcagcaa gcaagaaagc agatcgctga
     9601 tttgatccat gtagaaccag aagaaatcta ttttacttca ggcggaacag aaggagataa
     9661 ctgggtatta aaaggaacga tgatcgaaaa aagagaatat gggaatcata tgatcatttc
     9721 aggagtcgaa catccggccg tcagcgagac agcagaacaa ttaaaagaat taggaatcga
     9781 agtaagtatc gccccagtgg ataaacgcgg atttgtacgt gtcgacgaat tgaaagaatt
     9841 aataagaaaa gagacagtat tagtctctgt tatggctgtg aataatgaag taggatcgat
     9901 tcagcccatc caggaaatca gtgatctttt ggatgatttt cctaaaattc atttccatgt
     9961 agatgctgtt caggcgattg gaaaagtacc attctcgcaa tggttgacag aaagagttga
    10021 ttttgcaaca ttttcagctc ataaattcca tggcccacgg ggaactggtt tcatttattg
    10081 gaaaaagggt cgtcgtttag caccattact gacaggtgga gggcaagaaa gaaatcagcg
    10141 aagtgggaca gaaaatgttc caggtattgt ggctatggtt aaagctttac gtttatcatt
    10201 agagataaag gaacaaaaac ctgagcagac acaacgctta aaagtagctc taatcaatgc
    10261 gttgaagacg tatgagaaag tgacgatttt ttcagaagga actgactatg caccgcatat
    10321 tttatgtttt gctctaaaag gaattcgcgg cgaagttctc gtccatgcct tagaagaaaa
    10381 acaaatattt gtttctacta ctagtgcctg ctcctcacgt aaacatatgg caagcagtac
    10441 attgcacgca atgcatgtac caaatgatct ggctacatct gctgttcgaa tcagcttaga
    10501 tgaaaacaat tcgcttgcag aagtcgagca atttatgatt attttcaagc agctttataa
    10561 gaaattttct gcaatcaatt aaaagaggag tgttcttgtg aaatacagtg aaattatggt
    10621 ccgttatggg gaactttcga caaaaggaaa gaatcgaaaa agctttatca tgcaactagc
    10681 acaaaatgtc agacaagctt tgaaagactt tccagaaatc aaaatccatg ctgatcggga
    10741 ccggatgcat cttttattga atggcgcaga cgggcagcta gttattccaa aactagcaaa
    10801 aatatttggg atccaaaatt tctctccaag tattcgtgta gaaaaagatg tcgaagtttt
    10861 gaaacaagct gttcaagaca tcatgaaaga aatttatact gggaaagaaa catttaaaat
    10921 tatcgctaaa agaagcgatc accaatttga attgacaagt aatgaattga atcaaacatt
    10981 aggtaatgct gtttttgata ttttcccgca tatccaagtt caaatgcgtc aaccagatat
    11041 tccattacgt gtagagattc ggcgtgatgg cgcttatcta tcgtatgaaa cgatcaaggg
    11101 agctggagga ttgcccgtag gaacaagcgg aaaaggaatg cttatgcttt ctggggggat
    11161 tgattctcct gtagcagggt actttgccat gaagcgggga gtggaaattg aagctgttca
    11221 ttttgctagt ccgccgtata caagtgaaca agcactgcaa aaagcaaaag atctaacagc
    11281 caaactagca ccttatgtgg gaacgatcca ttttatcgaa gtgccattta ccgagattca
    11341 agaagaaatc aaaaagtcag tgccacaagg atattggatg acaattactc gtcgaatgat
    11401 gttgcgtttg accgatgaaa ttcgccgtat tcgtcatggt ttagtcattt tgaatggtga
    11461 atcattaggt caagtggctt cacaaacttt gcaaagtatg gtggctatca atgaagtaac
    11521 gaatacgcca atcattcggc ctgtagcgac aatggataaa cttgaaatca ttgaagtagc
    11581 agaacagatc gatacattta atctttctat ccagcctttt gaagattgct gtacgatttt
    11641 tgctcctcca cagccaaaaa cacgccctca actggaaaag gtccatcaat atgaagagcg
    11701 tttagcaata gatgaaatga tccaacgagc actagctggc ttgaagatgg aagagataca
    11761 agcagaatcg tctaatgaaa aaactgaaga attttcagaa ttgctataag aggttatgaa
    11821 aatagtgttt tgaccagagt attagagaaa caaaacgaaa aaatagctcc atgtatttta
    11881 ccgtttttga actaatgtcg aagattagct gattgaatac catttatcaa gaagttatgg
    11941 aaaagccggt tcttttttac taactgaaaa ataaaatttt atttagagat caagctacag
    12001 ttgataaatg atataaaaaa gagaatttcc catgaaatag cgaggttgtg acagaagtgg
    12061 gcagcttcaa gaaataagaa ggaatttacg aaaattgctt ttcaaatttt tgtgaaattt
    12121 cggcttattt ttcgaagaag ttacttctgg aacaccgtgt atcagaggtt g
//
LOCUS       DACGEU010000084        12152 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.085, whole genome shotgun sequence.
ACCESSION   DACGEU010000084 DACGEU010000000
VERSION     DACGEU010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12152)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12152)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12152
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.085"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(45..602)
                     /gene="frr"
                     /locus_tag="IXR40_002224"
     CDS             complement(45..602)
                     /gene="frr"
                     /locus_tag="IXR40_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HAQ4362054.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(605..1327)
                     /locus_tag="IXR40_002225"
     CDS             complement(605..1327)
                     /locus_tag="IXR40_002225"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010761216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HAQ4362055.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(1463..2344)
                     /locus_tag="IXR40_002226"
     CDS             complement(1463..2344)
                     /locus_tag="IXR40_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HAQ4362056.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(2443..3225)
                     /gene="rpsB"
                     /locus_tag="IXR40_002227"
     CDS             complement(2443..3225)
                     /gene="rpsB"
                     /locus_tag="IXR40_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HAQ4362057.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            3584..4063
                     /locus_tag="IXR40_002228"
     CDS             3584..4063
                     /locus_tag="IXR40_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgR family transcriptional regulator"
                     /protein_id="HAQ4362058.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            4280..5371
                     /gene="phnW"
                     /locus_tag="IXR40_002229"
     CDS             4280..5371
                     /gene="phnW"
                     /locus_tag="IXR40_002229"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HAQ4362059.1"
                     /translation="MYKLLTSGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSSSFGVESVLSSVIRPEDTVLICSNGAYRQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQERDLL
                     FIVDAMSSFGGIPICVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            5364..5492
                     /locus_tag="IXR40_002230"
     CDS             5364..5492
                     /locus_tag="IXR40_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HAQ4362060.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIR"
     gene            5496..6041
                     /locus_tag="IXR40_002231"
     CDS             5496..6041
                     /locus_tag="IXR40_002231"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HAQ4362061.1"
                     /translation="MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEH
                     YLFKDLVKHSTLKPDTLETIERLRNAGINIGSTNGFNAPMMTIVAETAKKERYSPDFM
                     ATFEDVEGYGRPFPYMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEG
                     SSLMGISYDEYQKLEMGKKIV"
     gene            complement(6495..8186)
                     /locus_tag="IXR40_002232"
     CDS             complement(6495..8186)
                     /locus_tag="IXR40_002232"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HAQ4362062.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDKEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMHHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(8606..9553)
                     /gene="arcC"
                     /locus_tag="IXR40_002233"
     CDS             complement(8606..9553)
                     /gene="arcC"
                     /locus_tag="IXR40_002233"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HAQ4362063.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(9668..10687)
                     /gene="argF"
                     /locus_tag="IXR40_002234"
     CDS             complement(9668..10687)
                     /gene="argF"
                     /locus_tag="IXR40_002234"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HAQ4362064.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(10778..12007)
                     /gene="arcA"
                     /locus_tag="IXR40_002235"
     CDS             complement(10778..12007)
                     /gene="arcA"
                     /locus_tag="IXR40_002235"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HAQ4362065.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
BASE COUNT         3318 a         2527 c         2201 g         4106 t
ORIGIN      
        1 acagaggaag cggaatgatc cgcccctctg tttttatgat tttattaaac ttccaataat
       61 tctttttctt tatcagcagc gatcttatct acttctttga tgctgttatc tgtcaatgtt
      121 tgtacgtctt tttctaatcc gcgcaaatca tcttcggtaa tatcaccatt tttttgttgt
      181 tttttatatt catcgatcgc atcacgacgg atgttacgaa tcgcgatttt tgcattttct
      241 gcttcttttt taacatcttt agctaattct tttctgcgtt cttctgtcag ttgcgggata
      301 actaagcgaa tgacatttcc atcattggtt ggactgattc cgatatcact tgccataata
      361 gctttttcaa catcttgaag aatgctcttg tcaaaaggtg tgatcattaa aacacgtgct
      421 tctggaattt ggattgatgc catttggttc aatggtgttg gcgcaccgta gtagttcaca
      481 gtaatacggt ccaaaaggct agcgttcgca cggcctgcgc ggatttgccc aagttcacgt
      541 tgaagatttt gtgctgcttt tttcattttt tcttttgctt ctgtcataat tgcatctgcc
      601 atttttattt cccccttaca gttgttccga tattttcgcc taagattgca cggcgaatat
      661 ttccgtgttc atttaaattg aagacaagca gtggaatatc attatccatg cttagtgaac
      721 ttgcagttga atccatgact tgtaatcctt tggcaataac ttccagatga gtcagttctt
      781 caaattttac tgcatttgca tctactttcg gatcagcaga ataaacaccg tctacattgt
      841 ttttagccat caggataaca tctgcgccga tttctgccgc gcgtaatgct gctgttgtgt
      901 ctgtcgagaa gtacgggttg ccggtaccgc ctgcaaagat aacgatccgt cctttttcta
      961 aatgacgttc tgctttacgg cgaatatatg gctctgcgat ttgacgcatt tcaatcgaag
     1021 tttgcacgcg tgtcggtaca cccacgtttt ccaacgtatc ctgtaaagct aaggcattca
     1081 taactgtagc taacataccc atgtaatcag cttgagcacg ttccatgccc atttgtgctc
     1141 cgatttgtcc gcgccagata tttccgccgc ccacaacgat tgccatttca acgcccagct
     1201 cgtgaacttc tttgatttct tggatgattt ctttgattac tggtggtttg attccaaatc
     1261 ctgcgtcccc agctaaagct tctccactca attttaagac tacacgctga tatttcggtg
     1321 tgaccatgtt cattcctcca atattttcta ttgccatttt accatactta gatgatttcg
     1381 acactctaag actggttttt cttgttttgc ttaaaaaaag ggagcgcaca aaccgtgcgt
     1441 tcccgtctgt tattcaacag aattattttt tcacttggct cataacttct tctacaaagt
     1501 tatcttcgcg tttttcgata ccttcgccaa cttcgaaacg tacgaatgtt ttaacagttg
     1561 cgccttttga tgcaacgtat ttttcaacag tcatatcagg atctttaacg aatggttggt
     1621 ccaccaaagc gatttctgct ttgaatttct tcaagcgtcc ttctaccatt ttttcaacga
     1681 tattcgctgg tttgccttcg ttcaatgctt gttctgtaag aacagttttt tcatgttcta
     1741 attcagcttc tggaatttgt gattcgttta cataacgagg attgatagct gctacgtgca
     1801 tagctacgtc tcttgcaact gtttcgtcag ttgttccatc tagaacagtc aatacggcaa
     1861 tacgtccgcc catatgcaag tatccaccaa atgcagcatt gtcgtctttt tctacaactt
     1921 caaagcgacg gaagctgatt ttttctccga taacttgagt tgcttcgatc aagtcagatt
     1981 caattgtacc tttatctgtt ttgattttca ttgcagcttc catgtctgct ggtttgtttt
     2041 cagcaacaag ttctgcaatt tcttttacta aatcttggaa catttcgttt ttagaaacaa
     2101 agtctgtttc tgagtttact tcaacgattg ctgcagtgtt acctttcaca gcaactgaag
     2161 ccaatccttc agctgcaatg cggtcatttt tcttcgcagc ctttgccatt cctttttcac
     2221 gtaaaagatc aactgctttt tccatgtcgc cttctacttc aactaatgct tttttcgcat
     2281 ccatcattcc tacgccagtc atttcgcgta gttcttttac cattttagct gtaacgtctg
     2341 ccatgtttaa ctcctcctgt gtgtttttct ttttaaaaaa agctgcttca aaggagagtg
     2401 aggcttgtcg cccagccttt gaaacagctc catcattcaa aattattctg ctgaagaatt
     2461 gtcgccttca acaacatcta cgatttcttc gattgatgtt gctgtgtttt cttctgtgaa
     2521 atcttcttca actacttgat cttcaccttg gtttccttcg atgaaagcat cagccatttt
     2581 tgaagtaatc aatttaacgg cacgaattgc atcgtcgttt gaagggatta ctacgtcgat
     2641 ttcatctgga tcgcagtttg tatcaaccat agctacgatt gggatattta atttgtgtgc
     2701 ttcttgaaca gcaatacgtt ctttacgtgg gtcaacgatg tacattacat ctgggattct
     2761 tggcatatca gcgataccgc ctaagaattt ttcaagacgt tcacgttctt tgttcaaacc
     2821 agcaacttct tttttaggta gaacttcaaa agttccatct tcttccattg cattgatttg
     2881 tttcaaacgg ctgatacgtt tttggatagt atcccagttt gtcaatgttc cgcctaacca
     2941 acgatggtta acgaagtatt gtcctgcacg agttgcttct tctttgattg cttcttgtgc
     3001 ttgttttttt gtacctacga ataatgctac gccgccttct tcagcaacgc tcttcatgta
     3061 atcataagct gcatctacta atttaactgt tttttgcaag tcaatgatgt agattccgtt
     3121 tctttctgtg aagatatatt tcttcatttt tggattccag cgacgagttt ggtgaccaaa
     3181 gtgtacgccg gcttctagta attgtttcat agaaattact gccatgtttg tttcctccga
     3241 tttggtttta tttttcctct tcttatcttc taccttgccg gcaaactttt tcaagcacct
     3301 accgacaatc caataagaat gtggatttgc tgatgcataa agcaccctca gctattatac
     3361 agacaaaaga tccgtatcgc aagagcaaat atacttttct gctcaacatt caatagttta
     3421 cctgaaagat aaaaagaatt caagaaaaac agtagatttc tctttgtttc tttattatcc
     3481 tttttccata aaataatttt aggtataaaa gacgaatatt attgggcaat ccttcttttt
     3541 tttgttatga tacatgtgaa atctttcgta aaggagaaag aaaatgcgca aagctcaaag
     3601 acatttgctg attaaacaag tcattgaaga attcccgatc cgtacgcaag aagaactatt
     3661 aaacaaactt gggcattatg gcgttaccgc cacgcaggca acgatttctc gagatatccg
     3721 tgatctaaaa atcgtgaagg cacctgatga aaatggcgtt tcccgcttcg tattgtttcg
     3781 cgaaaaagga actcctgaga ctaggactga ggaagaggat cggctggttc aaatgattga
     3841 agacattgta ttgaaagtcg aacgagtcca ctttttgacg atcgtcaata ccttgccaga
     3901 caatgctcat ttatttgcat ctgttttaga tgagatcaaa cctccctcta ttgtcagtac
     3961 aattgctgga ttcgatacga tcatggtcat ctcggaaaat gaggaggacg caaaacgagt
     4021 agaagaattt cttcaccatc caactgaagt atcacttttt taatcagagc acgtattcct
     4081 aatatggaat gcgtgttttt ttattttcaa tattttcctt attgaataaa cctttacact
     4141 ctttacaaaa atacatcatt ttttattcaa atttttcaac accttgattg aatcacaata
     4201 atcatcattt atattggatg ttaacaagag cagcttcttg ctctttgtgt atttcaaaaa
     4261 agaaatgaaa ggaaatcata tgtataaatt attaacttct ggaccattga cgacttctga
     4321 aacagtgaaa aatgctatgc tgatcgatca ttgtacttgg gatcaagaat acaaagaaat
     4381 tacacaatgg ataagaaaaa aattattgga tcttgctcaa gtatcggaag gaatatacac
     4441 aacggtctta atgcaaggta gcagctcctt cggggtagaa tcggtattaa gttctgtgat
     4501 caggccagaa gatactgtac tgatttgttc aaacggcgca tatagacaac gaatgatcaa
     4561 catgtgcgaa tgtctgaaac tgaactatac cgtttatgag gtatcggaac atcaaatcct
     4621 ccaagctcat gtgattacac agctgattga agagaatccg tctatctccg cactagcaat
     4681 ggtccatagc gagactactt ccggtatttt gaataatttg gaagagattg ctgctgtcac
     4741 acaagaaaga gatcttttgt ttatagtgga cgcgatgtca agctttggtg ggataccgat
     4801 ttgtgtagcc gaactaggga ttgatttttt gatttccagc tcaaacaaat gtattcaagg
     4861 tgttccaggc ttttcttttg tacttgctaa taaagcggaa ctggaaaaac gaaaaaatgt
     4921 tagccgaagt ttgtcacttg atctatatga ccagtaccgc gtgatggaaa acgagaatgg
     4981 caaatggcgt ttcacttccc ctacccatac ggttttggct tttcaacaag cgctgaagga
     5041 actagaggca gaaggaggaa tcgaaactcg atattcacgt tatctcgcca ataatcatgt
     5101 gctacgacaa aaaatgacag agatggggtt ccagcctttc attcaagaat atcaggggcc
     5161 attcatcacc tcttttcttt accctaagga ctggcgattt gattttaatc atttttatca
     5221 gtatttaaag caaaatggat ttgtgatcta tcccgggaaa atcagcgatc atgaatgttt
     5281 tcgtatcgga aatattggcg agatctatcc ggaagatatt ttggaactga cagcaattat
     5341 caaagactat aaggagaacg ttaatgatta aaactgtaat ttttgattgg gcaggaacaa
     5401 ctgtggactt tggctgtatg gctcctgtcc acgcttttag aaatgctttt ctagaaaaag
     5461 gaatccaact gactgacaaa gaaatccgct aaccgatggg aaaattaaaa tgggatcata
     5521 tccaacagct tctttccctc ccttctgtca aaaaacaatg gatagctatt tatggacaac
     5581 tacctcagga aaaagaggtg gaggaattgt atcaacaatt tgaacattat ctgtttaaag
     5641 atttggtcaa gcattctacc ttgaaacccg acacattgga aacgatcgaa cggttgagaa
     5701 acgctgggat caatattggt tccacgaatg gatttaatgc tcctatgatg acaatcgtag
     5761 cagaaaccgc aaaaaaagaa aggtattcac cagacttcat ggcaactttt gaagacgtcg
     5821 aagggtatgg tcgaccgttt ccttatatga tccataaaaa catgcagtac ttcaaaaaca
     5881 agtcggttga tgaagtaatc aaagtcggag atacggtctc agatatccag gaagggaaaa
     5941 atgccggagt gttgacagta ggtgtaattg aaggtagttc gctaatgggg atttcttatg
     6001 atgagtacca aaaattagag atggggaaaa agatcgttta aaacagtctg ttgctcttag
     6061 attccaacaa gccggcgctg atatttgtgt aaacaattta aaagagttaa cagaatacat
     6121 tttgtacgct gacatgaatc cagaatgact tttatacaaa ataagaggtt gtgaaaaagc
     6181 tgtcctgtat caagtaataa aaacagccaa gcaaaaatag ctcctcatat ttttcgtttg
     6241 gttaggctta ttaccgcaga tgcaagcttt tgaacaccgt ttattcgaaa aaaaaaaggg
     6301 agctgtgaca cgacttttgt cacagtcccc ttatttgcaa acaaacagtg tttaagagac
     6361 aacctctcca ctaaacggtg ttcattcagc tgactctcgg tatttgctca aaaaacgata
     6421 aaatttgaaa agctattttc tcttttgttt ctctaatact cggatcagaa cgctgatttc
     6481 acattctctt tttcttacat cttatctggt gcatgaagtc ctagcaaacg aaggtcttct
     6541 ttcaataata cagtcactgc ataaactaga gctaagcgtg cttctttttg ttcatcatca
     6601 gctaaaatct tcgtatgagc atagtatttg ttgaatgctt gtgctaattt gattgcatgt
     6661 ttcgcaatca ctgacggttc gtatttttcc ccagcagaca agaccgtttc agggtatttt
     6721 tgaactaatt taaccacttc ccagctggta tcgtcattca atgcatagtc tgctgtttct
     6781 gaagggacaa atcctgcttt ttccaacagg ctgactgcac gagcatgtgt atattgcaca
     6841 taaggtccag tttctccttc aaatcgaaca acttcttcca ggttaaagtc aaatgtattc
     6901 agtcgatcgt ttttcaaatc gtggaaaatg actgccccaa ccccaacttg tttagctaca
     6961 gcatctttgt tttccaaatc agggtttttc tcgctgattt gttctttagc agattggatt
     7021 gcttcattta atacttcttc taataagacg atctttcctt tacgagttga taatttttta
     7081 ccaccttgcg tgatcaaacc aaatggaata tggtgcatgt cgtcagacca gtcaaagccc
     7141 atttccttca agacagcttt caactgttta aaatgatagc tttgttcatt ccctactaca
     7201 tatagagatt gtttgaagtc gtaagtacgt ttacggtaca atgcagcagc taagtcacgt
     7261 gtaatgtata gtgtcgcacc gtctgacttc ttaatcaacg ctggattcag gtcataagca
     7321 gataggtcaa cgatctctgc acctttatcc tcgttcagca aatgtttttc ttctaaaagt
     7381 ttgacgattt catccatctt gtcattgtag aaagcttcac cgttcaacga atcgaaacgt
     7441 acttccagca gatcatagat tttattgaat tctttcatcg attcatcacg gaaccattgc
     7501 cataattgaa tagcctcttt atcgccttct tccagacgtt tgaaccaagc acgagcttct
     7561 tcatttaatt ctggttctgt ttcagctact tcatggaatt ggacgtataa acgaagcaat
     7621 tcattgattg gttctgcttt aacagcttct tctgtacccc attttttgta agcgacgatc
     7681 agttttccaa actgtgttcc ccagtcacct aaatggttga tgcggattgg ctgataaccg
     7741 attttttcca taatgaaacc gatcgaatta ccgataactg tcgaacgcaa atgtcccatt
     7801 gagattggtt tggcaatatt aggagaagac atgtcgattg gtactgttcc ttgattcccg
     7861 atgttgctat ccccataatg ttctttttct ttcactactg tttgcaaaac ttttttgctg
     7921 ataagttctt tattcatgaa aaagttcaag taaggtccga caacttcgat tttttcaaag
     7981 ttggcagaat cgattttttc tgctaaatct gcagcgattt gctgtggcgc ttttcggtaa
     8041 acttttgcta atgaaaaggc tggaaatgca acatctccgt gttcagctga ttttggattt
     8101 tctagtaatt gctcgacttg ttccagtgtt aaatcatctt tgacagcgtc atagacagct
     8161 tttgcgacaa gatctttatt attcatcttt attcctccta aagtgttccc ttgattgtta
     8221 aacaaaaaaa atctctagcg acggcatact tagtatgcca tcactagaga cgagatttcc
     8281 cgcggtacca ctccaattgt cctaaaaaag gaccagctcc atctgatatc ggtagacgac
     8341 cgtctgttta aaacagaatt ctccaagtgc gcttcgttgt atcttcttca ttcggcttcc
     8401 accacttccg aattcgctag ccaagaatga tacaagtact ctcttgttca acaaatctta
     8461 gtcttattaa actttcttga attatatcag aaaaaaaaac gaaaggctag tcgtttcata
     8521 aaaaaacaat ccagatggcc taaaggagaa gaaataccac ctggatagct ataaatcatt
     8581 tcgtaaatac gaaagactta acaaattaat cagctacgat aatcgttcct tcttcagaag
     8641 ctaaaagatt ctcgatattt tctaaagaag tgatgattgc cttagcgttt ggttttgctt
     8701 caacaaatgc aatagctgct tctactttcg gaagcatgct tcctggagcg aattgctttt
     8761 catcaatgta ttgtttcatt tctgaaacag taacagtttc taatttcttt tgatctggtt
     8821 tttggtaatt gacatacaca ttgtctactc ctgtcaatac gatcagcaaa tccgcatcga
     8881 tgatttcggc taatttttct gaagcaaaat ctttatcgat tacggcttct cgtccttcta
     8941 atccagtagc tgtttctaca acaggaatcc caccgccacc aacagagact gtgataactc
     9001 cttgatcgac cagcgtttcg atgacacgtg cttctttaat cgagatgggt ttaggggaag
     9061 cgactacttt tctccatcca cgtccagcat cttctttgaa tgtcacagtg gagtcagcat
     9121 tcatttgttc tttggcttct tcttccgtgt agaatggacc gactggttta cttggatttt
     9181 tgaatgaagg atcattttca tccacaataa cttgagtgac taaagaaacc acatctttat
     9241 cgatcccttt ttccttcagt acttcgccca tggcgttttg taaccagtaa ccgatagatc
     9301 cttctgtcat tgcaacacat gtatctaaag gcattgccgg tgttttctca gaatcagcag
     9361 cttgctgctg aatcaatagg ttaccgactt gcggaccatt tccgtgggag atgatcaatt
     9421 catctccttg ttcgataaat ttcactaaat actttgctgt ttccattaac gcttcttgtt
     9481 gggcttttgc acttgcatcc gtagacaaga tggcattgcc ccctaaagcg acaactactt
     9541 ttcgtttggc catttcattc gtcctttctt cagttctacc gaattttcta gataacaaaa
     9601 cgagccagcg ttttgtgatt ttccctcaat gctgactcgt tttttcgtga gatgaatgtg
     9661 gttatgctta aacgcgaggg ataaacaagt tacctaatgt tgctgccatg atcgctttga
     9721 ttgagtgcat acgattttct gcttggtcaa attgacgagc atatttgctg cggaagactt
     9781 catctgttac ttccatttca gtgatgccaa agcgttcttt catttgttca ccgtaaacag
     9841 tgtttgtatc atggaaagct ggcaagcagt gcaagaagat caaacgatct gtgttgtgtg
     9901 ttttttctac catttccata ttgatttggt aaggtttcaa caatttgata cgttcttcga
     9961 atttatcttc ttcacccatt gatacccata catcagaata aaggacgtct gctccgtcta
    10021 cacctttatc aacatcgtcg gtaatcatca attgtgcacc ggatttttca gcaaagcctt
    10081 ctgccatttt gacgatttct tcttcaggtt gtaattcttt tggtgcaacg atacgcatat
    10141 tcgctcctaa aattgcacct gtgactaata aagagttagc catattgttt cgaccatctc
    10201 cgcagtaagc aacagtgata ccttctactg ttccaaagtt ttcttggata gttaaaaagt
    10261 cagcgatcat ttgtgttgga tgccattcat cagtcaagcc attccaaact ggaacaccag
    10321 agaattctgc tagttcctct accatttttt gactgaatcc acggaattcg attccgtcaa
    10381 acatacgtcc tagtacttta gctgtatctt ctgtggattc ttttttacct aattggatat
    10441 catttgcacc tagatattca ggatgtgcac ctagatcgat cgctgcagta gtaaatgcag
    10501 aacgagtacg tgtagatgtt ttttcaaata aaagcgcaat attttttcct tctagatagt
    10561 gatgtgggat accacgtttt ttcaagtctt tcaagtgttc tgaaaaatcg atcaaatatt
    10621 gtaattcttc ttttgtaaag tctttttctg ctaataagct tcttccttgg aatactgatt
    10681 ctttcatatt aaacattctc ctttagattg tttttattta agattaaaga ggaaatcccg
    10741 acggcagctg acagtaagac tgccgtcagg aaacaaatta cttcaagtct tcacggacaa
    10801 gtggttggct catgcagcgt ggaccaccac gacctcgtga caattcactt gaattgattt
    10861 ctaacacttt gatgccatag ctacgaagca attcgttcga tacataattt cggttataag
    10921 tgactacaac acctggagcg attgccaatg tgtttgatcc atcattccat tgttctcgag
    10981 gtgcaacgat ctcatctcca ttaccagttg ggatcagtac aagatcatct aatccaagag
    11041 cagctttcat cgtttcgtgt aagttatctg aatgagtaat cttgatatca tcaccatctg
    11101 gttcgattgt aaagacatcc atcttaccgt ctttactttg aattgctgga tggatagtga
    11161 atttatcgtg atctaccatt gtaaatacgg tatccaaatg catcattgca cggttgttcg
    11221 gaattttgat tgccaacact ttttcaaatc ctgaattttt tgcgaatagg tggcgtgcta
    11281 atttttctaa agctttcgca ttagttcgtt gagaaatccc aacagctact actttatcgc
    11341 ttaagatcaa ttcgtctccg ccttcgatat gatctggatt ttcacgatcc aaccatactt
    11401 cgattccttt atttgcaaat cttggatgat gtttcaaaat atattctgta aacatcgatt
    11461 cacgacgacg tgcttcaaaa gtcatcttat tgactgtcat cccatttccc attgatgcgg
    11521 aagggtcgcg tgtaaagtac aagtttggca ttgggtccat gtaaaatgga tagtcatcgt
    11581 ctgctgacag atcatataga ctgctagaac gtacttcgat atcttttgta cgaaccccag
    11641 ccatgatttt atctaccatt tcttgcgttt ccattgatag aaggaactca tgaagaccct
    11701 ctcttacagc attcgatgca atatgagatt catccaacat tttattcaag aattgttctt
    11761 tgacattgcc tgcgtcaatc gcttctgccg ctaatttttc caagtaaaga gtctcgacgc
    11821 cttcattttg caatgtcttc gcaaagttgt catgttcttc ttgagcaatc ggaagatatg
    11881 gaatatcatc gaacaacaga cgatccataa tatctggtgt caaattttcc acttcttgtc
    11941 caggccgttt cagtaaaact gtctttaatt tccctatttc agagaaaacg tgaataggtt
    12001 tatccatgtt gtgttgcctc cttctttttg attacatgta taggatatcc tccttttgta
    12061 atcactttca taattttgtc tcattcaaaa tgagacattc ctcacattaa tattcgataa
    12121 ttaaataatt aaacgttttt ctatttttaa gc
//
LOCUS       DACGEU010000085        12149 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.086, whole genome shotgun sequence.
ACCESSION   DACGEU010000085 DACGEU010000000
VERSION     DACGEU010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12149)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12149)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12149
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.086"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            75..977
                     /gene="gnd"
                     /locus_tag="IXR40_002236"
     CDS             75..977
                     /gene="gnd"
                     /locus_tag="IXR40_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating 6-phosphogluconate
                     dehydrogenase"
                     /protein_id="HAQ4362066.1"
                     /translation="MEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDI
                     PAYQEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSI
                     RRAEEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLY
                     AGASGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWL
                     MEIMEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEED
                     SFSAKVVSALRNGFGGHEIVEKGE"
     gene            979..1980
                     /locus_tag="IXR40_002237"
     CDS             979..1980
                     /locus_tag="IXR40_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HAQ4362067.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALIERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            1977..2261
                     /locus_tag="IXR40_002238"
     CDS             1977..2261
                     /locus_tag="IXR40_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HAQ4362068.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            2294..3091
                     /locus_tag="IXR40_002239"
     CDS             2294..3091
                     /locus_tag="IXR40_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HAQ4362069.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNAAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            3105..3938
                     /locus_tag="IXR40_002240"
     CDS             3105..3938
                     /locus_tag="IXR40_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4362070.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            3956..4813
                     /locus_tag="IXR40_002241"
     CDS             3956..4813
                     /locus_tag="IXR40_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAQ4362071.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLMQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            4835..5344
                     /locus_tag="IXR40_002242"
     CDS             4835..5344
                     /locus_tag="IXR40_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAQ4362072.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            5381..5782
                     /locus_tag="IXR40_002243"
     CDS             5381..5782
                     /locus_tag="IXR40_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362073.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            5894..6247
                     /locus_tag="IXR40_002244"
     CDS             5894..6247
                     /locus_tag="IXR40_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362074.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            6281..6724
                     /locus_tag="IXR40_002245"
     CDS             6281..6724
                     /locus_tag="IXR40_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HAQ4362075.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            6741..7826
                     /gene="uxuA"
                     /locus_tag="IXR40_002246"
     CDS             6741..7826
                     /gene="uxuA"
                     /locus_tag="IXR40_002246"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HAQ4362076.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            7819..8532
                     /locus_tag="IXR40_002247"
     CDS             7819..8532
                     /locus_tag="IXR40_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAQ4362077.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
     gene            9284..9484
                     /locus_tag="IXR40_002248"
     CDS             9284..9484
                     /locus_tag="IXR40_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAQ4362078.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
     gene            10052..10615
                     /locus_tag="IXR40_002249"
     CDS             10052..10615
                     /locus_tag="IXR40_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362079.1"
                     /translation="MLYIKKGIIVISFFKEYLEIINFRLKTKKESVIILVYFQGGNLM
                     IKKLFLLSILTLAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGIL
                     GRSNCKHRCSNRRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREV
                     GDEPKLEYAFSFAREDEDNPKTYDILA"
     gene            complement(10676..11041)
                     /locus_tag="IXR40_002250"
     CDS             complement(10676..11041)
                     /locus_tag="IXR40_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362080.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(11117..11362)
                     /locus_tag="IXR40_002251"
     CDS             complement(11117..11362)
                     /locus_tag="IXR40_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4362081.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            complement(11432..11686)
                     /locus_tag="IXR40_002252"
     CDS             complement(11432..11686)
                     /locus_tag="IXR40_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362082.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            complement(11850..12062)
                     /locus_tag="IXR40_002253"
     CDS             complement(11850..12062)
                     /locus_tag="IXR40_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362083.1"
                     /translation="MIFQGVITLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIIL
                     SFLVNAIVLFLYVLNYLDINPLIFSR"
BASE COUNT         4168 a         1910 c         2582 g         3489 t
ORIGIN      
        1 aaaatatttt tgtaaaatct atttacaaaa aaattttttt gtataatgag ggtataagaa
       61 atggaggcgc tatcatggaa attggtgtaa ttggtttggg aaaaatggga ttgaatttag
      121 ctttaaactt aaaagagcac catcacaaag tacaaggact cgacatttca agtacagctg
      181 ttagtcaggc aagagaaaat gacattcctg cttatcaaga gatctctgaa tttctagcta
      241 cttttgagca gaaaaaaatc atctggttaa tgcttcctgc tggagagata accgaaaaca
      301 tgttaagaaa actttttcca aaactcggac caggagacat tattattgaa ggcggaaact
      361 cttattataa agattcaatc cgtcgagcag aagagtttca gaaaaatgaa atcggttact
      421 tggattgtgg gacttctgga ggaatcgaag gagcacgaca tcaagcctgc ttaatgattg
      481 gaggagataa agaaactttt ctatccgtgg aacaattatt caaagatgta gcaattgaaa
      541 gaggatatct gtatgctggt gcatccggaa gcggacactt cttgaaaatg atccataatg
      601 gaatcgaata tggaatgatg caagcaatcg gtgaaggatt ccaacttgta caaaaaagtg
      661 agtatgcttt tgacttggaa caagtcgcac gtgtttggaa tcatggttcg gtgattcgcg
      721 gctggctgat ggaaatcatg gaagatcagt taaacgaaca tcccaattta agtaattatc
      781 ggggaatcgt ttctgcatca ggtgaagcaa aatggacggt tgaaacagcg ctagaaatgg
      841 ctgttccagt tccagtaatt gcaactagtt tgttcatgag gaatctttca caggaagaag
      901 atagtttttc agcaaaagta gtttcagcac taagaaatgg gtttggcgga catgaaatag
      961 ttgaaaaggg tgagtaaaat gccagattat catatagcaa tcgttaattc cagcagtttc
     1021 ggaagagtct ttccacacca cttggaaaga ttaaagtcag ttggagacgt tcatttcttt
     1081 actgttgatc aagagattcc aggaaaagaa ctagcggagt tacttaaagg attcaatatc
     1141 attattgcaa gtgttacgcc attttttcga cgagattttt ttgaaaacaa agatgaactg
     1201 ctattgattt cccgacatgg tattggttac aacaatattg atttaaaagc agcaaaagaa
     1261 caccagacaa tcgtatctat catacctgct ttaattgaac gaaatgctgt agcagaaaat
     1321 aatataacta atttgttgtc catgcttcga cgcacgacac aagcacaagc aagagtcaag
     1381 gacgatcgat gggaagatcg ggcggagttc gtcggtagga cgctgtttaa caaaacagtt
     1441 ggtgtgattg gtgcaggaaa taccggaagc ggagtaatcg aaattttgcg taacggtttt
     1501 cgctgtgatg ttctagctta tgatccttac aaatcagatt tatacatcga aagctttggt
     1561 gcaaaaaaag tagaacttca agaattactg gaacaatcag atatcatttg tttatgtgcg
     1621 aatttgacag aagagaacta tcacatgatt tctgataaag aagtcgatca gatgaaagaa
     1681 aatgtttatc tatctaatag tgcaagaggc gctctagttg atgaagaagc gatgattaat
     1741 ggtctgaaaa gcggaaagat cgcaggatat gccacagatg ttttagaaga agaaccggga
     1801 cgtcaagatc atccgtattt agcgtttgaa caagtagtga ttacgccaca tatatcggcc
     1861 tacacaaggg aatgtttaga agcaatgggt gaaaaatgtg tcagagatgt cgaacagatc
     1921 agtcagcacc ttcttcctga acgttctgtc cagacaaaga gcaactatat aaaaggatga
     1981 tgaagaaaat ggtgaacggt ttaaaagtga aaacaggccc tcaattttat ttatatgaag
     2041 aaggtggtat ttcaaaagtt tctgatctct tgaaatcata cggcgcgaaa agagtactgg
     2101 tcacccacgg aacggtatca tgggaaaagg cgctacctaa attagtattt ttgaatgacg
     2161 aaacgattca atttttttat catcgttatt ctggagaatg tagttatgct gaagccagac
     2221 gaatagctac aatcatcaaa aaaatgaaat cgatttcgta gttggcgttg gcggaggaaa
     2281 actgaccgat ctagtgggtt atagtgccaa tcttgcaaga atcgatttcg gagtcatccc
     2341 tactttagct agtaattgtg ctccatggac acctcttgct gtcatgtata aggagaatgg
     2401 acaagcagaa gggaaaacag aacactttta cagacaagct gcttttttta taacagatcc
     2461 ccaattagtg attgattccc ctgttccata tttcattgcc gggttagcag atacactagc
     2521 aaaatggtat gaatctgagc tcatcttaga acaagatttt ttgcaagatg aatcattttt
     2581 gaagctagca caagatactg cgaagatctg caaagaagag attttgaatc attctgctaa
     2641 agcaatccaa gatatggcac aaagaaaact gacatcggag ttcaaacagc tttcagagat
     2701 tatctttgct gttgctggtt tagttggagg attaggagat aaatacgcaa gaaatgcggc
     2761 agcacatgct atgcatgacg ctatcagtaa atatattccg gaaagccatc gttttctaca
     2821 tggagaaaaa gtagcgtatg ggattttcta tcaactggca ctagaaggtc gctgggaaaa
     2881 aatagacgag ttatatcctt tgtatcggga attagaactg ccggtttctc tagaacaaat
     2941 gggattattt ccgaaagata aacagataat agataaaatg gctgaattta ttgattcgaa
     3001 agagaaagtg catttgattc ctatagaggt aacacagaaa tcactgatac agtcaatgat
     3061 ggaactggaa ggttatatca gaaagatctg aaggaggagg acacatggaa acattaagtg
     3121 tagtacaaag tttgttgatt gctttatggg tagccgcggt tatgtcccgc tggttaggtg
     3181 gaggagccac gttgacctta cgtttttctc ctttgatgac tggattagtc gtcgggttga
     3241 tcatggggga agttgcacaa gcgatgattg ttacagccgc tttgcaaatg atttatatgg
     3301 gggttttttc tccaggagga tcaatgccag ctgaaccatc tattgcagca gctatcgcag
     3361 taccagtcgc attattaggg gatctgtcgc cagaagcagc gattgccgtt gcggtgccag
     3421 tcggattgct cggaagttac ttgtatcagt ttcgtttttt catcaatact tttttaggta
     3481 aatatacaga caaagctgta gaagatttga atacaaaagc tatggcccga tcaattattc
     3541 tttatccaac ggttgcctca tttttattat tcgttccgct tgttttcatt gctttatatt
     3601 taggggcgcc attgatcgct gatgtaatca aagctttaga gggaacagtc gttatccaca
     3661 ttcttgaagt agtaggtgga gggttagcgg caatcggtat cgcgacaact gtatacgtta
     3721 tcggtcgaaa agattatctg gtctttttct tccttgctta ttttatgagt gttgttttga
     3781 aatctttaga tattacgatg gttacttatg ccatttttgg gattattatc gctttgatct
     3841 ttgtccagtc gcaaaaaggg aaacaagtac agcctgccac aagcaataac aattcagcat
     3901 cttttgatga cgaagatgac tatgatgacg gattttaatt taggaggaat gggaaatggc
     3961 tgaaataatg gataatcaaa caggtgctcc tgaagaaatc acgaaaaaag atgtaacaaa
     4021 agcctatctg agatggcatt ttgcaaacga aattcctcac tcttttgaac gttacttggc
     4081 gccatcacta ctatacggaa tgatgccaat cttgaaaaaa ctttataaag atgaagactc
     4141 tttaaaagca gcatataaac ggcagttact gttcttcaac actcaattaa gctggggtgg
     4201 cggtgtgatt actggcctaa tgtcttctat ggaacagcaa agagcagaag aagagtatga
     4261 agaaaaagag atcttgatgc aggatgactt gatgtataac acgaaagcgg gattgatggg
     4321 ggcactagca ggaatcggag atgcaatcga ttcaggaacc gtccaatata tttttatcgc
     4381 aatcgcggta ccttgggcac aacagggaag tcctttaggc gcactttttc cttttatctg
     4441 ctttgggttg tatcaggttt tactaggggt atttttcgca agacaagctt tcactatggg
     4501 ccgtaatgct acaggcctaa tgcaaaacac tggtgttcag acagcgattg aaatgctatc
     4561 agttttaggg ttgtttatga tgggggtgct tgcgggaaac tatgtaaaag tagaatcttc
     4621 attgaaattt gcgatatccg gacgtgagtt tgttatccag gaaattcttg atcaaatcgt
     4681 gccagggata ttacctttag ctgtcgtaat gggtgtgtac ttgttctata cgaaaaaagg
     4741 attgaaagtc acacaagcat tattatggct gactggaata ttaattgtgc tagcaggaat
     4801 cggtatttta taaaaagaag ggaacgtgaa taagatgggt gtagtcaatt tagcgcgtgt
     4861 ggatgagcgt ttgatccatg ggcaagtaat ggtaacgtta tctcaaaaaa gtggagtgaa
     4921 ttccattttt gttgtagacg aagttgtagc aaaagataaa tttatgagag atctttacaa
     4981 aaatgcagga agccgtacag gacaaaaaac aattgtcatt acaccagaga aagctaaatt
     5041 ctattgggat gaatatcaat ttaaagaata caattgtatt ttgatcgcaa aaacagtcca
     5101 aacgatttac gacttagtaa aacacggaat ccccatggaa gaattgaata ttggagggat
     5161 tgctcaaaaa aatcctgata cagatctttt agtgacgaaa tctgtttatt taaataaatc
     5221 agatgctgaa aaattgaaag aaatgaatga acaatatggc gtaaagaata tttattttca
     5281 agccactcca tctgcaccta aaacaggatt aaaagatgta ttgaacaagt ttgatttgtc
     5341 ataaacaaat gcttagaaaa aagataaaga gggcgaaaaa atgaagaaga acgagctgtt
     5401 tcgtgattgg gaatttcgtt atcgctatat ttaccgtaag cgccgtacaa aaaagagtaa
     5461 acagcgtttt ctttcagcat tagtatcaga tatttacagt atgagaacag atgtgacagt
     5521 cattgcttac gatacgctag cctaccgatc aaaaaatatt tatgttggag atatcgaaaa
     5581 agcagagaaa gttatctgta cttattacga tacacccgtt catgcattag gaagttattt
     5641 catgtttgat tggaaagacc aaaggaaaaa aacaatctac tctatattat tgtccttcat
     5701 tttgttgttc agtttaggtt ggtggggaat gatgatatat aacaaaaatc ctcatcacgt
     5761 attcgatctg ctatccgtat aaacaggtat cactgtacta gcatttggga gctacttttt
     5821 cttattggga aaagcagctc gcggatggcc tagcagacaa acttttattc gaaatacttc
     5881 atccatatta acgatgctag aaatgatccg tacgattgat gatccgagtg tagcgtatgc
     5941 gtttgttgat gaaggctgtt atggagaaaa gggcttagac agcgtgagat cgggtatgaa
     6001 aaaagaggct attctttttt atctagactc tgttggggca gatacaccgc tacagttttc
     6061 gggaaattat ttttcaaata aagaacagtg gctgaaacaa gttgataagt tgaaagaaaa
     6121 aaacgtcaat tatattttta gtgcaagaaa aaagcaagcg cagttcttct atttgaccaa
     6181 aacagattta cgagggaaaa catttaattg gcaaaatgcc aatcagatta ttgctctttt
     6241 tcgataagta aaaagtgcaa aacaaggagt gagaagacta atgttggaaa tcatgatcgt
     6301 tacacatggt aagttgagcg aaggactgaa agatgcggcg gaagtaattg tcgggacatc
     6361 gagccatatt gaaacaatgt gcttagagtc tggggaggac atccaaacat tcggagagaa
     6421 ggtcaaagaa aaattaacta tgatcaacac agcagaaccc atgctagtat ttgttgatct
     6481 aattagcgca agtccgtaca atcaagcgct cttggcagtc aatgaactga ctgaagaaaa
     6541 gaaagcagcc acttatgtca tagggggcgt gaatctgcca atgttgttag aagcaatcaa
     6601 tcatcagatg cttcacacac cgatagaaga agcggtggaa caaattgtca aacaaggaaa
     6661 agataattta actgtttggc atgcttcagc ggaagaaaaa aaattagatg aggacgattt
     6721 ttagaaggaa ggctgaaaag atgaagtggg gatttagatg gtatggtgaa aaaggggatt
     6781 cgatcccatt aaaatatgtt cgccaaatac cgggaataaa tgggataatt ggaactttgc
     6841 tgactaaaat gcctggagat gtttgggaga tttcagaaat tgaggagttg aaagcatctg
     6901 ttgagagcca aggactggaa ctgcttggaa ttgaaagtgt agcgatccac gatgcaatca
     6961 aggcagggac agatgaacga gattactata ttgataacta tatacgaaca atcaaaaact
     7021 tgtctcgatg tggggttcga ttgatttgtt atagcttcaa accaattttt ggatgggcga
     7081 aaactgattt gtttaatgaa aacaacgatg gaagctattc tcttttatac gatcagaaaa
     7141 tcgtcgatca gatggagcca ggagaaatgt atcaattgat acacagccag tcaaagggat
     7201 tcaaattgcc gggttgggaa gaagaacggt tgaaaaaatt cgctcagctg gaaaaactgt
     7261 atgaaggaat gaccgaagaa gaattatttg aaaatctgac ttatttttta gaaaaagtga
     7321 ttccagtgtg cgaaaaagca gatgtaaaaa tggctatcca tccagatgat ccgccatggg
     7381 aactttttgg ttttcctaga gtgacgaaaa atcttggcga cttgaagaaa attctaaatg
     7441 cagtagattc tccatataat ggactaacgc tgtgcacagg atctttaggg gcaaatccgg
     7501 aaaacgattt agttgaaatc atccatgagg taggttcgcg catccatttt gtccacttca
     7561 gaaacgtgga gtttttagga gaaagaaagt tcaaagaaac ggcacatccc tctacagaag
     7621 gctcccttga tatgtatcat attatgaaag cgttggtgca agaagggttc gacggtccta
     7681 tacgccctga tcatggtaga accgtgtggg gtgaagtggc tatgcctgga tatggcctgt
     7741 atgatcgtgc aatgggactc acttacatgc aaggtctata tgaggcgata agtaaggaaa
     7801 aaccactggg agagcattat gaataaaatc aagctcttca tctttgatat ggatggcctt
     7861 ttattagaaa ctggacgttt agcttatcgt gcttatgtaa aatcagcaca aaagtatgat
     7921 tatgaaatgc gtaaggaagt ctattattta ctaactggcc aaacagaaat ggcgataaga
     7981 gaacaaatgg gcattttgta cggagaagat gttccatata tcaaatggcg agaagcaatc
     8041 aatcaatata aagaaaaaat cgtgaaagaa gataagagag tatatacgaa aaaaggagca
     8101 gaagaaattt tatcttttgc aaaagaaaga ggaatccata caatcgtggc ttcgtctaat
     8161 acacgggtaa aagtagaaat gtatttaaaa atggaaaatc tatatgcctt gtttgatcaa
     8221 atcatttcag gggatgatgt aaaaaaagga aagccggaac cagagatctt tttgaaagct
     8281 tgttcaaaaa tgaatattcc tccaagtgaa gcacttgtat ttgaagactc gattgcaggg
     8341 atcgaagcag caaggcgagc gggcattttg tcttttctca tcaaagatca tttgataggg
     8401 ttgcccgatc ataatgggaa gcataagttg aaagtagatg taagtttata tgaatccaat
     8461 aaagcagact atgaatttta tgacctgcat caagcaaaac gatttttaga aagtaaaggg
     8521 ttgtatctct aataaagagg actattttct agtcctcttt atttattgtc ctgcacgact
     8581 gagggaacag atgaaaaaga agtaattttt tattttgaag tatctacctt atttgtagtg
     8641 aacaatttag aacaaacaca aaacgcatct actgttatct accagtagat gcgtttaaag
     8701 agaagaacga gaatcgtcca tatgagggtt tccactcctt atgcagattt ttttaattct
     8761 tgcactgctt gttcgatcgt aacacctgtc gctacatgat tggtattttc tttgtcaaaa
     8821 acgacaaata gattcaaatc tgtatccaag gttactcgat attgtatatc tttgttatag
     8881 aatgtcatag ccattctcct ttctttaaat acttgctgaa aggcaacgaa cgcgttgata
     8941 acgaaattcc atttataagt ataccaccaa ttgaaaggtt ttcatagtta agaaatttta
     9001 aagtcaaaag ttgcagataa aagcaaataa acaagaaaac aaaaagtgaa tcaatcgcgg
     9061 ttattcaact ttttcttcga ttcgaagaca atagaagaca atgaatttta tatttcattg
     9121 cattatcctt gtgttattag aaaaagcatg atatattaaa tgagtaatct attttgaaac
     9181 gtaatttgag cgatatatct acatagataa aactcctttt gcctatcaaa tatttattgc
     9241 aacgaaaaaa cgtacattga tacgtatcag gaggaattta tttatgaata acggtacagt
     9301 aaaatggttc aacgcagaca aaggttttgg ctttatcact ggtgaagatg gaaatgatgt
     9361 atttgcacat ttttcagcta tccaaggtga cggcttcaaa actttagaag aaggccaagc
     9421 agtgtcttac gatgttgaag atggtcaacg tggccctcaa gcaacaaaca ttgttaaagc
     9481 ttaataaaaa ttgactttta accgtctttt cgaaagaaaa gacggttttt ttgtacgaaa
     9541 aaattcattg gtcgttgaat gggctgaata gtagtgtata aaacaatttt gtggagcgtg
     9601 aagcttttat ggtagaggaa aatacgaata aagtgatgtt gataaaaaga ttcctatctt
     9661 gaatatgaat cgagatgtct tgaaaatgaa tgagtttgac caatcattat cctatcgaaa
     9721 tttacagttt cgttcgattg gtctgtcaat taatgaaaaa gtaaaaaaga atatgttcta
     9781 ggaagagggc ggcacatcta aatttttaag taacggacag ttcaaatatc aagcattgaa
     9841 agaggctatc ctactgtttg aaggaatacg aatatataaa aacgacaaag aggaaaaagt
     9901 agttcattaa atcccttcaa gtgatgaaag aatgagatct aataaaacct gatctttcat
     9961 ctgttttttt aataacgtaa taattttttt attttttgtg ctttcgccgt tattgtagag
    10021 tgatttagca ttcttatttt taaaaataac tgtgttatat attaaaaaag gcataatagt
    10081 tataagcttt tttaaagaat atttagaaat tattaatttt cgtctgaaaa caaaaaaaga
    10141 aagcgttatt attttagtct attttcaggg ggggaacctt atgataaaaa aactattttt
    10201 actatcaata ttaacgctag caatggcagg ttgttctgac tctggcttag caactgaact
    10261 gatcacaaaa tcaactgaag ccacgacaga ggagttaaaa tgtggaaacg atcacagtga
    10321 ctacagaggc ttaaatcgac gatgcatggg aatattaggc agaagcaatt gtaagcatcg
    10381 atgtagtaat cgaagaaggt gtagaagaag caacagaaaa atcaaaagaa agatcaaaag
    10441 aagcaatctg tgctgtgcat cgtatacaga cgtcgaagat gcggtacttt taaaccacgt
    10501 caggagatgt tcatttatgt ctagggaagt tggcgatgaa ccaaaactag agtacgcttt
    10561 tagttttgca cgtgaggatg aagataaccc taaaacttac gacattttag cttgatctaa
    10621 gatggttaaa gctttttaat gaagtaagag gagatagaag gcttttctag ttatattagg
    10681 taagataaat tcctttttgc tccaaatttg ctaaacattc tgctagataa acttcatcgt
    10741 gttccggata aatcggcacg ttgcgctcta cagtaggtaa atcaaaaaat gcttcgcatg
    10801 atttgccacg atacatagga tttttccact ctggtgctgg gctgtaacca cgtttttcca
    10861 tttcatccat gacaagctga tgatattgga ataatctata aggagaatag tgaaaaacat
    10921 aatccacagt agcatgtttc tttccccagc catttcctct taatgcacag cattcccgat
    10981 gttgtcctaa aagctgttga cgaggaagct ttgaaatcaa tttttcatgc cataatcgca
    11041 tagaaatgtc tcctttatat atagattgtt aaccttagac gttaaatgaa aaaaccagca
    11101 ccaaggctgg aaaaaatcac ttcagtttgc ttgctgtttc tgagcgacca attaggtaat
    11161 caacggaaat atcgtaaaag tcagcgatat agattaattc aatgatgctt ggaatttctt
    11221 ctccttcttc gtacttacga tatttgaata aaggaatact taacgcgcta gaaacagcta
    11281 cttgagataa agatcggcca gttcttaaga aattcagacg acaacgtaaa gtatccagta
    11341 aaatagcttc ttcgatactc atttaatcac ctttcattat agtagaatag ttataatgac
    11401 tatagaaagc tacacatgca atcaatagta ctcaatgttt tttatttaaa cgtatcaaat
    11461 aaagaatgac gatcaataaa gacaaaacca gtcctgataa ttcttctata aaaacactat
    11521 cgggttcaaa gtagttgtaa ttaaaaactt tccacataaa gtagatagcc ggaagagtca
    11581 aaatagctaa ataaaaccgt tctttgttcc aattcataag ataaacaata cttgcgacca
    11641 gtgcgaccgc aggcacccaa aacaaaactc tcaccaacgt aatcatgtaa cggactcctc
    11701 aacgattcat ataataaaag ataacatgtt attgcataca tcacaaatga aatgctagga
    11761 aaataaaaga agaatagatc aatgaaaaat gaaaaagcag aacagttttc tgctgataag
    11821 caggaactgt tccgctgaat gtgtcttatc tatcgagaaa aaatcaatgg attgatatct
    11881 aagtaattca atacatataa aaagaggacg atcgcattca ctaaaaagga aagaatgatg
    11941 atcccatagc gaatggaaac atatttaaca aatacttttg tttgaatacg ggcatatctt
    12001 tttcctttat agctgagcat catgacaaga agcaaaaggg taatcacacc ttgaaaaatc
    12061 attccaataa acagaattcc tgaggtttga taatttaatt ggagaaaata agctgctgcc
    12121 gcaactaaat cgaataaaat cgcaataaa
//
LOCUS       DACGEU010000086        12065 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.087, whole genome shotgun sequence.
ACCESSION   DACGEU010000086 DACGEU010000000
VERSION     DACGEU010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12065)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12065)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12065
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.087"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            <1..895
                     /locus_tag="IXR40_002254"
     CDS             <1..895
                     /locus_tag="IXR40_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HAQ4362084.1"
                     /translation="AVSVPLILNKREKNNLKKKMLIPFDSEVKGLLNKLTISNIDSTR
                     EKIIKIFDKINNLFKNDNAELRKGLLEFKLQELELHYSYLVKITEEKEQQKAIKEQMI
                     EEEKVRREIDREKKRIDKEQRQFNSEISKLIAYMQKANADVEKELYANKIQELEEKLK
                     ELEVIRENVLQRELNTRAGYVYVISNIGSFGEDIYKIGMTRRLEPMDRIKELSSASVP
                     FEFDVHAMIFSEDAPSLETKLHNHFRKQEVNKINQRKEFFKVSLDEIEKVVLENYNGT
                     VTFTKLAKAEQYRRSLELSKD"
     gene            967..2088
                     /locus_tag="IXR40_002255"
     CDS             967..2088
                     /locus_tag="IXR40_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAQ4362085.1"
                     /translation="MWLEKINDKKFKYTERYTDPLTEKKRKVSVTLSSNSRQAWNQAN
                     LLLNEKIAEKIKRNEELPLTFGELKTKWDEKYKPTVKESSYRTTQVYLSLISKYIKDD
                     VLVKNVNSNLIQDMLDYYYFEKNLSYNYVIHLKTFTGMIFKFANRRYGLKYNPVNGVS
                     LARKPKTNEEIKKEKDGYLSKEEVQMIASKQKSSHQQSRYSLITKFLFLTGLRYGELI
                     SLTESDYDGNKITVSGTYDYELKIKTTTKNTGSYRTIELSSNAKEIIDQLIEENKLIK
                     NNKDKYIFISKNGNPISIQAYNQSLRAVSKELNLDKKVSSHMLRHSHISLLTELGIPL
                     KAIMDRVGHEDSKTTLKIYTHTTKNMQNQLVEKLGKIEI"
     gene            complement(2170..3942)
                     /locus_tag="IXR40_002256"
     CDS             complement(2170..3942)
                     /locus_tag="IXR40_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4362086.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENGKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFES"
     gene            complement(3945..5657)
                     /locus_tag="IXR40_002257"
     CDS             complement(3945..5657)
                     /locus_tag="IXR40_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4362087.1"
                     /translation="MKLILRHAKKYKVSVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            5772..6440
                     /locus_tag="IXR40_002258"
     CDS             5772..6440
                     /locus_tag="IXR40_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HAQ4362088.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQKMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            complement(6507..7295)
                     /locus_tag="IXR40_002259"
     CDS             complement(6507..7295)
                     /locus_tag="IXR40_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HAQ4362089.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(7378..8850)
                     /locus_tag="IXR40_002260"
     CDS             complement(7378..8850)
                     /locus_tag="IXR40_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAQ4362090.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            complement(8980..10173)
                     /locus_tag="IXR40_002261"
     CDS             complement(8980..10173)
                     /locus_tag="IXR40_002261"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HAQ4362091.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            complement(10439..10510)
                     /locus_tag="IXR40_002262"
     tRNA            complement(10439..10510)
                     /locus_tag="IXR40_002262"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10475..10477),aa:Glu,seq:ttc)
     gene            complement(10522..10595)
                     /locus_tag="IXR40_002263"
     tRNA            complement(10522..10595)
                     /locus_tag="IXR40_002263"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10559..10561),aa:Ile,seq:gat)
     gene            complement(10608..10678)
                     /locus_tag="IXR40_002264"
     tRNA            complement(10608..10678)
                     /locus_tag="IXR40_002264"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10644..10646),aa:Gly,seq:tcc)
     gene            complement(10683..10755)
                     /locus_tag="IXR40_002265"
     tRNA            complement(10683..10755)
                     /locus_tag="IXR40_002265"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10720..10722),aa:Phe,seq:gaa)
     gene            complement(10759..10831)
                     /locus_tag="IXR40_002266"
     tRNA            complement(10759..10831)
                     /locus_tag="IXR40_002266"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10796..10798),aa:Asp,seq:gtc)
     gene            complement(10850..10923)
                     /locus_tag="IXR40_002267"
     tRNA            complement(10850..10923)
                     /locus_tag="IXR40_002267"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10887..10889),aa:Met,seq:cat)
     gene            complement(10936..11025)
                     /locus_tag="IXR40_002268"
     tRNA            complement(10936..11025)
                     /locus_tag="IXR40_002268"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10987..10989),aa:Ser,seq:tga)
     gene            complement(11048..11119)
                     /locus_tag="IXR40_002269"
     tRNA            complement(11048..11119)
                     /locus_tag="IXR40_002269"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11084..11086),aa:Glu,seq:ttc)
     gene            complement(11141..11228)
                     /locus_tag="IXR40_002270"
     tRNA            complement(11141..11228)
                     /locus_tag="IXR40_002270"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11192..11194),aa:Ser,seq:gct)
     gene            complement(11253..11326)
                     /locus_tag="IXR40_002271"
     tRNA            complement(11253..11326)
                     /locus_tag="IXR40_002271"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11290..11292),aa:Ile,seq:gat)
     gene            complement(11340..11410)
                     /locus_tag="IXR40_002272"
     tRNA            complement(11340..11410)
                     /locus_tag="IXR40_002272"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11376..11378),aa:Gly,seq:tcc)
     gene            complement(11412..11487)
                     /locus_tag="IXR40_002273"
     tRNA            complement(11412..11487)
                     /locus_tag="IXR40_002273"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11452..11454),aa:Asp,seq:gtc)
     gene            complement(11506..11579)
                     /locus_tag="IXR40_002274"
     tRNA            complement(11506..11579)
                     /locus_tag="IXR40_002274"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11543..11545),aa:Met,seq:cat)
     gene            complement(11592..11681)
                     /locus_tag="IXR40_002275"
     tRNA            complement(11592..11681)
                     /locus_tag="IXR40_002275"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11643..11645),aa:Ser,seq:tga)
     gene            complement(11705..11778)
                     /locus_tag="IXR40_002276"
     tRNA            complement(11705..11778)
                     /locus_tag="IXR40_002276"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11742..11744),aa:Ile,seq:cat)
     gene            complement(11792..11865)
                     /locus_tag="IXR40_002277"
     tRNA            complement(11792..11865)
                     /locus_tag="IXR40_002277"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11829..11831),aa:Met,seq:cat)
     gene            complement(11893..11965)
                     /locus_tag="IXR40_002278"
     tRNA            complement(11893..11965)
                     /locus_tag="IXR40_002278"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11930..11932),aa:Ala,seq:tgc)
     gene            complement(11985..12058)
                     /locus_tag="IXR40_002279"
     tRNA            complement(11985..12058)
                     /locus_tag="IXR40_002279"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12022..12024),aa:Pro,seq:tgg)
BASE COUNT         3915 a         2540 c         2093 g         3517 t
ORIGIN      
        1 tgctgtttct gtccctctta ttttaaataa acgagagaaa aataatttaa agaaaaaaat
       61 gctcattcca tttgattcag aagtgaaagg attactcaat aaactaacta tttctaatat
      121 agactcgact agggaaaaaa tcataaaaat atttgataaa attaataatt tattcaagaa
      181 tgacaatgct gaattaagga agggtctttt agagtttaaa cttcaagaac tagaacttca
      241 ttactcttat ttagtgaaaa ttaccgaaga aaaagaacaa caaaaagcaa taaaagaaca
      301 gatgatagaa gaggaaaaag ttcgtagaga aattgatcgt gaaaagaaac gtattgataa
      361 agaacaacgt caattcaatt ctgaaatttc caaattaatc gcatatatgc aaaaagctaa
      421 tgcagatgtg gaaaaagaat tatatgcaaa taaaattcaa gaactggaag aaaaattaaa
      481 agaattagaa gttatacgtg aaaatgtatt acaaagagaa ttaaatacta gagccggtta
      541 tgtgtatgta attagtaata ttgggtcttt tggtgaagac atatataaaa ttggtatgac
      601 tagaagatta gaacctatgg atagaataaa agaattgagt agtgcatcgg ttccatttga
      661 atttgacgtt catgcgatga ttttttcaga ggacgctccg tctttggaaa ctaaattgca
      721 taatcatttt agaaaacaag aagttaataa aattaatcaa agaaaagaat ttttcaaagt
      781 ttcactagac gaaatagaga aagttgtttt agaaaattat aatggaacag taacatttac
      841 aaaattagct aaagctgaac aatatagacg atctttagaa ttgtcaaaag attaaatata
      901 taaaaagcct tcgggctttt tcttttaaca attaatagga acgtatattc gaaaggaata
      961 gaaataatgt ggttagaaaa aataaatgac aaaaaattta agtacaccga acgttatacg
     1021 gatcccttaa ctgaaaaaaa gagaaaagtg tccgttactt tatctagcaa ttcacgccaa
     1081 gcttggaatc aagctaactt acttttgaat gaaaaaatcg cagaaaaaat aaaacgaaat
     1141 gaagaattac cactaacttt tggagaatta aaaactaaat gggatgaaaa atacaagcca
     1201 actgtaaaag aaagttccta tcgaacaact caggtttatc tatcattaat ttcaaaatat
     1261 ataaaagatg atgtacttgt aaaaaacgtt aatagtaatc ttatacaaga tatgctagat
     1321 tactactatt ttgaaaaaaa tttatcatat aattatgtaa tacatttaaa aacttttaca
     1381 ggaatgattt ttaaattcgc caaccgtcga tatggattaa aatataatcc cgtaaatggg
     1441 gtttctttag caagaaaacc taagacaaac gaagaaataa aaaaagaaaa agatggttat
     1501 ttatcaaaag aagaagttca aatgattgct agtaaacaaa aaagttcaca tcaacagtca
     1561 cgttattctt taattactaa atttttgttt ttaactggac tacgttatgg tgaattgata
     1621 tctttgactg aatctgatta tgatggtaat aaaattacgg tttctggtac ttatgattac
     1681 gagttaaaaa ttaaaacaac aactaaaaat acaggttctt atagaaccat tgaattatca
     1741 agtaatgcta aagaaatcat agatcaatta attgaagaaa acaaattaat taagaataat
     1801 aaagataaat acattttcat ctctaaaaat ggtaacccga tatctattca agcatataat
     1861 caatctttaa gagcagtatc caaagaatta aacctagata aaaaagtttc ttctcacatg
     1921 ttaaggcatt cccacatttc tctacttaca gaattaggaa tcccattaaa agccattatg
     1981 gatcgtgtag gacatgaaga ttcaaaaaca acattaaaga tttatactca tacaactaaa
     2041 aatatgcaaa atcaactagt agaaaaacta ggaaaaatag aaatttaaat tgcccctttt
     2101 ctgcccctta taaaaacaaa caacataaaa tatataaaaa gaaccccgtt ataacgaggt
     2161 tcttttaatt taactttcaa atacaaattg attatgataa agttccgcat aaaatccatt
     2221 ttctgctaat aactcatgat gactgccttc ttcaatgact tccccatcac gcaagacaac
     2281 gattctatct gcattcaaga ttgttttcag ccggtgagca atcacaaagc tggttcttcc
     2341 tttgattgct tcatccattg ctttttggat ccttgcttct gttaccgtgt ctacattact
     2401 tgttgcttca tccaaaatca ataaagatgg atttgtgatg atcgttcgag caatactgat
     2461 caactgcttt tgacctgtac tgaataagtt attttcttcg gatatctctg tatcataacc
     2521 tttttctaac gtcatgatga agtcatgaat attcgcttgt tttgctgcat tgatgacttc
     2581 ttcatctgaa gcgtccggtt tgccgaatgt gatattgtct ttgatcgttc cggagaacaa
     2641 tacagattct tgcaaaacga ttcctacatg tctacgtaat gcatcaagat cataatctcg
     2701 gatatctatt ccatcgatga ctactgaacc atcattgaca tcgtaaaaac ggtttagcag
     2761 attcatgatc gtcgttttcc ccgatcctgt tggaccaaca agagcaacca tttctccttt
     2821 gtccacattg atcgagacat ctttcaagac tagtttttct ggagaataac caaaatctac
     2881 gtgctgcaac gcaagacctt tttcaacacc atcaaatgct ttaccgtttt ctggtttgac
     2941 ttcatctttt tcatcaaata tttcattcaa tcgtcttgcc cctgtaatcg ctaattggat
     3001 catgctgtat ccagatgaaa tctgcatcag tggttggtaa tattgttgtg aatactggac
     3061 gaatgtcaca actaagccta atgccaccga acgttccaaa tcaccattta atgctaacca
     3121 gccgccgaaa aagataacta tcgctgtatt gaccagtgac attccttgca tcatcggaaa
     3181 tagtagacca gaataagctt gtcctttgaa ggttgcttcg cgaacacttt gattatgctc
     3241 taagaatcct tcaatcgttt cttcttgtaa gccatttgtg atgatgacac gttgtccgct
     3301 gattttttca tccatataac catttagttt ccccacttca tcttgctgaa gatccacata
     3361 tttccgtgct ttgcggataa tcaagacagc tatcaaaacg gctactggag tggaagcaat
     3421 tgtagcccaa gctaactcta cattttggcg gaacatcatg atcaagatcc cgacaagtaa
     3481 aacagcattc gtgatgactt gaagcaaagc ttggttcaaa ctattttgaa tattatctaa
     3541 gtcactggta aaacgactta aaatttcacc gtcttgatga gaatcaaaga aacggatcgt
     3601 caatttttcc aatttgttga atagaccgat acgcattcgg ttcgttgact tccctactac
     3661 ttgtgtgaac aaaatactat agataaagtt ggctgcacta gctagtacat aaaacagcaa
     3721 gagtttccat attacagaaa caaatttgct tttatcgtct acgccttgca tcaagcctcc
     3781 tacgtaatta gctaattctt gaaaagcttc cccgatgtat tgaggtgcct ttacttgtag
     3841 ataggtagca atgatcactg tgataaagat aaagaaaaag gagagtttgt accgcttcaa
     3901 atagtgatag aaaaatttac ttgcttttat tagatcagtc atacttactc ctccgttcct
     3961 ttttgagttt caaagatttc ctgatagaca cggtttccag ctaccaattc ctcatgggtt
     4021 ccttcgccga ctaatctgcc ttcatccaat actaagatgc ggtctgcttt gacaacagaa
     4081 gcaatttttt gtgcgatgac aatcgtcgtt gttcccttca aatctcgatc gagtgcttct
     4141 cggaccagct tttcagagcg agcatccagt gcactcgtac tgtcatctag gatcaagatc
     4201 tttggattac cgataacgcc acgagtaatg gataaacgtt gcttttgacc accagaaaag
     4261 ttactgctac gttcttctat tggtgcttcg taacgatcag ataacttttc gatgaattct
     4321 tttgcttgag caatagaaga agcatgttcc atctcttttt ctgttgcatt ctttttccct
     4381 tggcgcaagt tttgagcaat cgttcctgag aataaaattg ctttttgcaa aacaaaggaa
     4441 accgtttgtc ttaaactctt ttcatttact tgacgaagat ctacaccacc tacttcaact
     4501 ttgccttctg tcggatcaaa tagacgaggg atcaattgtg ctagtgttga cttcccggca
     4561 ccagtcgccc cgacgatacc aaccatttct ccaggtttga tagaaaagct gatatcttta
     4621 agcgtatctg tatcctcacc aggataacga aaagaaacat ggtcaaaagt gacagaaccc
     4681 gtcaactctt gttctggaac gtctaaataa gtaagatctg gttcagcatc taaaatttcc
     4741 gcaatccgct tcagcgatac ggctgctctt gaagtcatca tcatcatcat tccgccaata
     4801 atgattgcca tcataatctg catcaagtag ttcatgaatg aagcaattcc accaattaac
     4861 gtaggatcat ctttaacaag atcgctcaca aaaaagatcg ccccaaccac agccaaattg
     4921 gcagccagca tgaaggacgg gatcatcaca gaaaataatg taccgactat gatgttgtgt
     4981 tttgttaagt cctcacttac tttgctgaat gacttcaatt ggttttcttc ttgtacaaaa
     5041 gatttcacta cacgaatccc tagtaagttt tcttttgcaa tgctattcac acgatcaatc
     5101 agtttttgaa tgatcatgaa gtgcttgccc atccttgtaa atgaaagtgc cgtaatcaga
     5161 aataccgtaa cgataagcgc tacgatgatc caccataatt gcggcatcgt gatcatagct
     5221 aaaatgaagg caccaataaa taagaatgga attcgaaaaa gtgattgcaa agaaatcatc
     5281 actaaatttt ggatttgcgt gatatcattt gttagacgaa caacaagatt tccagcagag
     5341 aactgttcga tatttccaaa tgaaaatgtc tggatctttc gaaatgcttc ttctcggata
     5401 tctgcactta cgccttgagc tacttttgca gagaaaatcg tgttcgttac acctgcggct
     5461 aatcctagca aagccagact gatcaggtaa ataccaattg ttttcatttc atcattatct
     5521 tctgtaataa tagcttccaa tacttgctgt agtaacttag gttgccataa tgctgctgca
     5581 accatgactg ctacggacag caaggaaata aaaacagata ctttatattt tttcgcatgt
     5641 cgtaagatta atttcattcg ttgattacac ccctttgttt aaattgacag gactaattta
     5701 acactgtaaa attagaccga ctaacaattt accatgttta aaaagataat gcaatacacg
     5761 aggttgataa aatggaaata aagctttctc aagcaatcat cattcaggcc gcctttgata
     5821 tcctggctga aacacaagct ctttcgcagc tttccatgcg aaacatcgca aacagaattc
     5881 atgttcaagc acctgcttta tattggtatt tcaaaaacaa acaacagctc ttgcaaaaaa
     5941 tggctgaaac aatggaagaa gaattagcgc ttccagatcc aactttgcct tggaatgaac
     6001 agttgctgca gtatatggaa aattactatg acctttatac acgtttccct tgtggggcag
     6061 aattagaaat caatactgtg cccgcttttc cgagtcgatt agaacatttg gagcaaatga
     6121 tccaattact tgttcgtgaa ggattttcag tcacccaaag tcatcaggcc attgcctctc
     6181 tccacaattt attgattgga cagttaatgg atcagcagca tgaacagcag cttcgacaaa
     6241 aaattatgga cggaaatgaa tttttgaaag aaacagttct atttatgcgt aattatgtag
     6301 ttgaaaatca attagaggga tttaaagaaa gtatgcagtc ccatgcagaa ttgaatgaaa
     6361 aagcactctt tctaacgagt gcacaaacct atattgaagg cttatgccaa caaaataaaa
     6421 gaagagaaaa cgagcagtaa aaaagctcct atagagatca ctatgtttgt gatctctata
     6481 ggagctatct ttttaagact ctttttttat ttttcttcca ttagccacgc caatgcacgt
     6541 tgaatccatt ggtcccagaa gatccagtta tgatcgccag gtccttgttc aaaggtgacc
     6601 gccaagcctt gttcctgcat agcagatacc atttcctgat ttgcctgata aagaaaatca
     6661 gattccccac aagccatata aaatcttgga actggttttc cgctttttac tagttctttc
     6721 aataagtatt gcggatcatt ttttgaacct tcgatttgat ccaatggtcc aaagatccct
     6781 tcccaaaaag atgctttacg aaccatcaaa agatcatcca ttcgatttcc tacagaaaca
     6841 gcgcctgaaa gagagattac tgctgcgaaa ttttctgatt ttgcaaggcc tagttttaac
     6901 gcgccatatc cgcccatcga taatccagcg gcatatgttt tttctctttt tcttgttaat
     6961 tgcgggaata attcatgaca aatctcaggt agctcttctg caatgaatgt ccaatacttc
     7021 atgtcataaa ctgtatctgt gtaccagcca agatcagtag atggcatgat gacagctaat
     7081 ccgtagtttg ctacataacg ttcaatcgac gtacgtcttt cccatacact atgattgcca
     7141 cccattccat gaagtaaata taaaacaggt atatccgttg tctcttgctc tgaactggtg
     7201 ccaatcacct tttttgttgt ttgcggtagt atcacattta gattgacttc catttctaac
     7261 acattcgaat aaatatttgc ttgaataaat gccatatttt cgccttcctt agtaagaagt
     7321 tatttttgaa taactttaaa tttgaatgat tcggctacgt acatatctta accgaaacta
     7381 ctgttttatt ttaccacttt tttcatgaac gaaaagcgtt aagaccaaag caatgatcac
     7441 gagtaacaag ccaactagat aaacggaatg taacccatca taaagaattt ttcttaatgg
     7501 taacaaaata tccgcatcaa tatatttagc cgtttgtgga ttcaccagtt tattcatgat
     7561 atctgcatca tttgttaaat ttgctgctgc aagttctcgt ttagttaccc catttatcaa
     7621 taaaccaaaa atagaaacca tgactgtttg accaattgtt cgaactaacg tattaaaaga
     7681 agttgctaca ccaagctggt cacgagatac actattttgt gcactgacag tcgaggtagt
     7741 catggtcaca cctaagccta taccgatgac cgttgatata gcaaaaaacc ataaatagtt
     7801 acttctgaaa ggcataagat acaaccaagc gcccccaata gctgcgatta gtagtccaat
     7861 tctcaagacc caatgagttt tcatttgagt catccacttg cttgcaagga aagaaccgac
     7921 catccagact agtgataatg gtgctaatac cagcccacca attgctgcat tcagccctaa
     7981 tacaccttgc atccacatag ggatataaac atcgattccc atcaaaaaac cactagccaa
     8041 tgctgcagcc aagttgacca caacaaatag tggatttttg aataaatgca tcatgatgac
     8101 aggatcttta gctctttttt cggcaaaaac aaaaatacct aacattacga tactacctag
     8161 cagcaaagca gaaacaagcg gactcattcc ttcgtctcct aataattgga accctaacag
     8221 caatgagaca agcatggcca tcaaactaaa actaccaaaa atatccattg gtttagactc
     8281 atgtatgatt tttggttcat ttaaatatag ccaaatcaaa ataattaata gaattccgat
     8341 cggcacattg ataaaaaaga tccagtgcca gctgatcgtt tcaacgatga atcctcccgc
     8401 aagcggtcca aaaacactgg caatccccca ggctgaacta ttcaaaccta aaacttttgc
     8461 tcgcttttca atagaataaa gatcgccgat gatcgtcaaa gctactggca tcattgcccc
     8521 agcacccatc ccttgaatcg cacgagcagc aatcaaccca atcatgcttt gagataaacc
     8581 gcaaaataac gaaccgataa taaacaataa tgtcccaaaa ataaagattg gtttccgtcc
     8641 cactttatcc gcaagttttc cgtaaatcgg agtaagcata gcgtttgtca gcaaataaat
     8701 cgaaaatacc cagttcatga tttccattcc atgtaatgaa ccgacaatcg ttggcatagc
     8761 ggttgttacg attgtacctt caatagccgt catgaacgtt gcaatgaaaa tactcactgt
     8821 gaccaaagta acatttgttt cttttttcat cttattcctc cctttcatta tgacaggatc
     8881 taaaaataga taaataatta ctatcttttt caagaggtta actgccataa aaaaagctgg
     8941 aacaaccacc acttggcgat cgttccagct gaatataact tattttgcta aacttgcttt
     9001 caacgcatct actttgtccg tatgttccca aggcaaatct acatctgtac gaccaaaatg
     9061 accgtaagca gctgtttgtt tgtaaatcgg acgacgcaaa tcaagcatct cgatgattcc
     9121 tgctggccga agatcgaagt tttctctcac tgcagcaatc agttcttctt ccggaaccgt
     9181 tccagtaccg aaagtattga ttgagatcga aacaggttga gcaacaccaa tcgcataagc
     9241 tagctgtact tctgctttgc gagcaagccc tgctgcaaca atgtttttag caatataacg
     9301 tgcagcatag ctggcagaac ggtcaacttt tgtcgcatct ttaccagaaa aagcaccgcc
     9361 accatgacga gcataaccgc catacgtatc aacaatgatt tttcttcctg ttaatccggc
     9421 atccccttga ggaccaccaa tgacaaatcg gccagtcgga ttgatataat atttcgtttg
     9481 atcatctaat aattcagctg gaataacttc cttcactact ttttcgatga catcatgacg
     9541 aattgtttca ttatctactg catcatcatg ctgtgttgaa ataacgattg tatctacgcg
     9601 ttccggttgt ccttgatcat catattcaac cgttacttga gattttgcat ctggacgtaa
     9661 atacgttaat tcatttgatt tacgcaaatc tgccaagcgt cgtaccagac gatgactcaa
     9721 agcgattggt aaaggcatca attctggtgt ttcatctaca gcaaacccaa acattaaacc
     9781 ttggtcacca gcaccaatct catctaatac gtctttttta tcttcatccc ggatctcaag
     9841 tgcttcatca actccttgag caatatcagg agattgttca tcaatcgcaa ccaatacagc
     9901 tgctgtatct ccatcaaatc cgaattttgc acgtgtataa ccaatttctt ttattgtttc
     9961 ccgtacgact ttttgaatat ctacatatgc cgtcgtagat atttctccaa atactaaaac
    10021 aagaccagtt gttacagacg tttcacacgc tactcgtgct gttggatctt gttttaaaat
    10081 tgcatccaag attgcatcac tgatttggtc agcaatttta tctggatgtc cttcagaaac
    10141 agattctgat gtaaataagt gtctttctac cattataatg attcccccta gttaaattcg
    10201 gttacaaggc atctccgtcc tgcggatcct ttcgggaact tgcaacgaac caagtatagc
    10261 agataaaaca gttttctgct cgtatttttt catttttttg cttaaaaaat ataaaaatat
    10321 tttacattag aactgtccaa aaaagcttag cacaatcatc cataaagata actctgctaa
    10381 gctttttaaa atcattcttt cagataaaaa gaaaaagata ctcaaaaagt atcttccatg
    10441 acccgtacgg gattcgaacc cgtgttaccg ccgtgaaagg gcggtgtctt aaccgcttga
    10501 ccaacgggcc aataaaataa atgggcctaa atggactcga accatcgacc tcacgcttat
    10561 caggcgtgcg ctctaaccag ctgagctata ggcccataaa aactaaaagc gggtgacgag
    10621 aatcgaactc gcgacaacag cttggaaggc tgtggtttta ccactaaact acacccgcat
    10681 aatggcgcgg gacagaatcg aactgccgac acatggagct tcaatccatt gctctaccaa
    10741 ctgagctacc gagccaaacg gttccgacgg gaatcgaacc cgcgatctcc tgcgtgacag
    10801 gcaggcatgt taacccctac accacggaac caatgttttt agtttttaat tgcgggagca
    10861 ggatttgaac ctacgacctt cgggttatga gcccgacgag ctaccagact gctccatccc
    10921 gcgataatat gaaaaaggag gataagggat tcgaaccctt gcacggtttt acccgcctga
    10981 cggttttcaa gaccgttccc ttcagccgga cttgggtaat cctccatgta aaactatatt
    11041 aaattaatga cccgtacggg attcgaaccc gtgttaccgc cgtgaaaggg cggtgtctta
    11101 accgcttgac caacgggcca ggtaaaacaa aatattgaaa cggagaagga gggatttgaa
    11161 ccctcgcgcc ggtttcccga cctacaccct tagcaggggc gcctcttcag ccacttgagt
    11221 acttccccaa aaccaataag attttgtact aatgggccta aatggactcg aaccatcgac
    11281 ctcacgctta tcaggcgtgc gctctaacca gctgagctat aggcccataa aaaactaaaa
    11341 gcgggtgacg agaatcgaac tcgcgacaac agcttggaag gctgtggttt taccactaaa
    11401 ctacacccgc atggcggttc cgacgggaat cgaacccgcg atctcctgcg tgacaggcag
    11461 gcatgttaac ccctacacca cggaaccagt gtttttagtt tttaattgcg ggagcaggat
    11521 ttgaacctac gaccttcggg ttatgagccc gacgagctac cagactgctc catcccgcga
    11581 taatatgaaa aaggaggata agggattcga acccttgcac ggttttaccc gcctgacggt
    11641 tttcaagacc gttcccttca gccggacttg ggtaatcctc catatgaaac ttacaacgcc
    11701 acaatggacc ttgtaggact cgaacctacg accggacggt tatgagccgt ctgctctaac
    11761 caactgagct aaaggtccag gctcttaaaa atcgcggcgg aggggatcga acccccgacc
    11821 tcccgggtat gaaccggacg ctctagccag ctgagctaca ccgcgaaaaa gatattcatt
    11881 atttaaatga aatggagcct agcgggatcg aaccgctgac ctcctgcgtg caaagcaggc
    11941 gctctcccag ctgagctaag gccccgtgtt taaatttata attatcggga agacaggatt
    12001 cgaacctgcg accccttggt cccaaaccaa gtgctctacc aagctgagct acttcccgtt
    12061 taatt
//
LOCUS       DACGEU010000087        11442 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.088, whole genome shotgun sequence.
ACCESSION   DACGEU010000087 DACGEU010000000
VERSION     DACGEU010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11442)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11442)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11442
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.088"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            6..431
                     /locus_tag="IXR40_002280"
     CDS             6..431
                     /locus_tag="IXR40_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362092.1"
                     /translation="MIVILVGCSNEKNKQTNQDNGVLKSGTMWKEEVGGLVYNLKIID
                     ETTWEYSESVWHPDPVQITVKRQKDYKGLERYKIVDSAGVREFINKSDSLFIVVPYEK
                     NGVKKIIFLGSSKDEKRTKEKLIHDGSQSNKYKLQKTSE"
     gene            428..670
                     /locus_tag="IXR40_002281"
     CDS             428..670
                     /locus_tag="IXR40_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362093.1"
                     /translation="MIASLFICPEGGITVAKAKTPFEKAASKILERRGVSETQWKQEV
                     LEKAQFDLLRGKDKDLEGYIYQREREKLVFDEIIKH"
     gene            688..990
                     /locus_tag="IXR40_002282"
     CDS             688..990
                     /locus_tag="IXR40_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362094.1"
                     /translation="MFESITMNFLTQPKVVAAVDIFRALQTAATSLKNNLMIFAAAAA
                     VASIVIGGLFFLFGRRGAENGKMHVGYVLMGVGVILAAASIVVSLFGLFGQTPQGL"
     gene            1060..3123
                     /locus_tag="IXR40_002283"
     CDS             1060..3123
                     /locus_tag="IXR40_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362095.1"
                     /translation="MYFTIAGNTKTDKELIKKATKEVGKRTSFLPKTIKYSVIETEEQ
                     LHVLGKVLEHESRSSVKLTLTLHDTEGKIEKAGTEYVFGPLDYQISEGFYPTLMDLIR
                     LDVFKETDETMSVEESYRNEKLLQVLEEELESDQRKVNQGSEVEVNEEVPWERPIFPK
                     KESKEKETVYVDEQADIPTQKSIFEEENDVMGQLEVDPFEETMEDEETAEVEVDPVEA
                     NEESTWTEGDSQEYIEPLISEEVEKNEIEIQKATVFDYILDQYPPEHEWMKEKNKLFL
                     NELYSKYQLPQTYQAFLESKEELISQGKGTLLEQLESVQSTNWHELAQEDLLATFEER
                     QQETDQEINEYATEQSSNWEKAKEELNKEEQRVIEEEVQKIKERYEKKRDNAYSLCVA
                     KINNFTQTNQEALSKEKENLLKERIKERKEEFYRGLRTDKLKISKELNEQLNKLYQTT
                     TEVLMEKYEKIQQELQVQIPKWKKEYEIQQQELKEQEEKQRQKEKEREQLELKKREQD
                     LAEQQMAIEKQRLNQEKEKEAAARKERQEQMDTLRQAQLNYLAQPQPTPSVAAVQTPM
                     NNQTNLTPSPQRSFNGWMVGCIASLSLLLGGGTVFAFNHINQSSQADSVATTTSIKEE
                     AQEQARKEYEQQLEELLNRTNQSTTESSMENSKESDSSKAKEGSSDSTVQSNTSESSE
                     SNEVK"
     gene            3123..5735
                     /locus_tag="IXR40_002284"
     CDS             3123..5735
                     /locus_tag="IXR40_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HAQ4362096.1"
                     /translation="MRVRETTKRKDKRFNLEKNRYLSHFYRYTPSGEELPEKHDKRIS
                     KKIFYSGLVYLPLEYLVTRVPEVFNRLEIVKGSLQGINLFQLQEMPQVFHFDSAGFWN
                     PFTPTTSLGTRLAISTVCVVPAVLMGLKMDMWFRPLADGQKGDNRLMTLKEIQQIYPQ
                     IPETKTTFPGYGGIPITHYKKYWYIQTDTVNTCIVGTSRSGKGQIEVLATIDNLSRAE
                     KQSSMVVNDPKTELYVGSKDELEARGYDVYAFNITDPLQSMSDNPLALIVKYWKRGDI
                     DTATQLTNTFTNTIYYDANASDNKYFNENAQKAVNALIFALLEQADQTGDYSKLTPNN
                     LVELLSEIGGFNYYPDPDNEFKQLNALDEFMNQLPPGNIAKKQYGATKIGSDKAKGNI
                     LSTAITGLNPFTLTKIAKMTSQSTIDYKSVGFPKYLDLKLHESLLNQRVVVEFYHKGK
                     KFHEERVKVGYKGFCEINFDCHLVAGDQVCLKYDHQGKEYVAWYEFSQRVLKDEEGNI
                     VYRKKRGETHLPELEKEAVLTLDEEKSNLLVESIRMHYTDKPMAIFMLTPDYDPSNHI
                     IVSIFLSQLYKELSTQCVKTKGDKCHRRIHFILDEFGNMPPMDNMEGIMTVTAGRNML
                     WDLFIQSYQQLYAKYGEQNAAIIKENCQTHIYIMSTDDNTIEEFSKKVGNKTVEQENS
                     TINSLGMNTHINRNVDSDRILTPERISTFLEGETIVLAPLKRQDLKGHKIRPYPIFNH
                     GETNLPYAYQYIEDFNPSWDINDIDIHCTHADLDLKALQIDYDYFLPDEYARNLYHGL
                     HDQLEEKNEENMFYKIVQSLENETAKKLLIQFYEEQAADRLQEYVEKLIKNKEISEMI
                     GKRLLLESEKVVKE"
     gene            5732..8263
                     /locus_tag="IXR40_002285"
     CDS             5732..8263
                     /locus_tag="IXR40_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362097.1"
                     /translation="MIIGGIFSGIADWWSGLFGEGDANPKTVTKVLQDYGNYLQYQDV
                     FSWIWNTFLWGLIKGLYNLNTLLEKTIYQSFDLKDLLNAAGVNALFQSLISKVLALFC
                     VVTLIYLGLKFFMSKHPPKVKNILVNLFMAMILIFGGSSLIDEGLNISKSFYGDVTAA
                     NKADKTGSPAFQIIQNNVIDVSTLLATDPNKVESLPTDKRNALTAKNFKTANINGIIT
                     PKQAKEMADKDKSGLSDLQKDRLRALQYRLELDDNGKEIPVQISDEGLAKYVYTSGYR
                     RYSSKPGIILAGESSLAVAYLFILFTIVTCIIELVFKKFYLVIAASTDFETGQRMKSA
                     IEDISQSFLLLAFTILELRIYTLMLSGIGDLHAAGKINGFLYVVALIVLTIALFKGSQ
                     SVTKIFGVDTSLKNGSNSLLSMFALGNIAKNVGSGAKNLASAGKSGLSHLNDIRKNGF
                     GHRKDVTPDNGEEQSDDKATTVPNSKKTVSEMFGKAKNGVSKAAEGLGYVNERGLKGT
                     AEDLTEKAKDTLEEKLDGTRAKELAEAVKNPSEALEKQKEKASEVKEGLKDAYGEGQV
                     NAAVKANTTTEKENQEGIVIPSVKDHQEALHSNENSIEEKNSIEERNSEEGKNGQLPK
                     TDPEQYRYKPNSDLENEKRISDLSKVNQEDKAENEGQLPKTDPEQYRYRSVNSENEKR
                     ISDLPKRNQEVQTDEDSIVLPNDNGIEVGTEKSTKIGLPKAQNLPMKDSRLNQFKEND
                     QSFVHQSTAGTVQMKPSRLPENGNLTTVSYNLSESGETGNASVQNVVTREAAPKPIQN
                     VHTGYKPANVAFTAPTKINVTRETKNRNNALKEQLLRDIKQDIKP"
     gene            8313..8645
                     /locus_tag="IXR40_002286"
     CDS             8313..8645
                     /locus_tag="IXR40_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362098.1"
                     /translation="MDKYINMKNPPRFSGEWKFFAFFFLDLLTLGGCFFWAKMVNNLV
                     HLPLFFALLNYGLWIAIALVIVWRPYNNPGQRQIFAIIESIFFADKNHYHALDPNRNY
                     HGTYKEDE"
     gene            8646..9239
                     /locus_tag="IXR40_002287"
     CDS             8646..9239
                     /locus_tag="IXR40_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362099.1"
                     /translation="MRVKGQNSVERKSILQFGKPEERSILDLFPYKSCTEEGVLITRE
                     DHFQRYYRVVSTDVEGLNEQEKLERMNQLTTVMRTYVPTIKLVSLTTETDLTEQIVQK
                     RQLLDKNRMEQSLGRNLQRLKKYEKKLVEEIQELKRAEQERPDLSFFFVIEGKTIKDL
                     QTRNRQLMRSSGILGLKPLYKKELIKILYRMNNMNDE"
     gene            9402..11426
                     /locus_tag="IXR40_002288"
     CDS             9402..11426
                     /locus_tag="IXR40_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HAQ4362100.1"
                     /translation="MLEAIKTAFSPQNDQKVLDPLKQLGNREIEILKSKGYDLDFLKQ
                     VMPQGGLNFDEEYVTYGNGYSRCVTVYHYTKNPTLFWLANLMNNPHTVATLDVSTDEK
                     QKVIDQINRALDELNDRSDNERKATDRNKSAEEYLELAEYARKLTSNGEISKQVKVRV
                     HVYGNTIQEVDERAQELIENLKGMDYRAVTYLHKTKRDWQSMFTMFDEQAEWFGNIKG
                     QSLPSLNIGGGFPFHHQTLKDPGGTQYGETMTGGPFVWNATYKNSVRLSTNTLLLGMM
                     GAGKSTVLKMIAEAHLAAGDFIWGFEKGKDFIPFLKEYNGIMVRLDGSDGMINPLEIF
                     ATRTYDEASSLYDDGSVKDLKINEAASYQTHLDKVVYQVQLVSPQLKGTMKAEFKTYL
                     NRFYEEYGTVPRGFTSSNSRSNTETQVTGKDPEAYPTFKEFLDFLGQLELPGASQEKK
                     NRKEEMESIVESLCETYGMIFDGHSTIRHLDQQQLVFFDIDSITGLDRGVQQCQMYMA
                     MTLIWNQALIQGRRQRRLIKEKQMEEQDFKRFLAMIDECHNAINPDFIETVNYVTNFQ
                     REMRKVEAMTVLATQSPQEMVPENMSSDNFSKLKKVFEFSSTKIFMRMDESILRHIEG
                     LVGKSMTNSELESIPQQNQGDAVINFGSKETIRVHFSPNKRQLKLFDGGK"
BASE COUNT         4235 a         1797 c         2347 g         3063 t
ORIGIN      
        1 ttgccatgat tgttatttta gtcggatgta gtaatgaaaa aaataaacaa actaatcaag
       61 ataatggcgt attgaaatca ggaactatgt ggaaagaaga agtaggtggt cttgtttata
      121 atttgaaaat tatagacgag actacctggg aatactctga gagtgtatgg catccagatc
      181 ctgtacaaat aacagtcaag aggcaaaaag actataaagg tttagaaaga tacaaaatag
      241 tagattcagc tggtgttagg gaatttataa acaaatctga ttctttattt attgttgttc
      301 cctatgagaa gaatggcgta aaaaaaataa tttttcttgg atctagcaag gatgaaaagc
      361 gaacgaaaga gaaattgatt cacgatggat cacaatccaa taaatataag ttacaaaaga
      421 ctagcgagtg attgctagtc tttttatttg tcctgaagga ggaatcacag tggcaaaagc
      481 taaaacgcca tttgaaaaag ccgcgtctaa aatcttagaa cgccgcggtg tatctgaaac
      541 acagtggaaa caagaagtcc ttgaaaaagc acaatttgac ctattacggg gaaaagacaa
      601 ggacttagaa ggatatatct atcaacgtga acgtgaaaag cttgttttcg atgaaattat
      661 taaacactaa aaggagcgaa caattttatg tttgaatcaa ttacaatgaa ttttttaaca
      721 caaccgaaag tagtagctgc ggttgatatt tttagagcat tacaaactgc cgcaactagt
      781 ttaaaaaaca atctgatgat ttttgctgct gctgcggccg ttgcttccat tgttattggg
      841 ggtcttttct tcctatttgg acgaagagga gctgaaaatg ggaagatgca cgtaggctat
      901 gtattgatgg gggtaggagt tattttagca gcagcttcta ttgtggtttc gttatttgga
      961 ttgtttggac aaacacctca aggattataa gaaagtaaaa aagtaggagt aagaagtagt
     1021 cgatactttt tactcctttt ttatgaaagg agaatactca tgtactttac gattgcaggc
     1081 aataccaaaa cagataaaga gttaataaaa aaagcaacga aggaagtagg aaagcgtact
     1141 tcttttttac cgaaaacaat taaatattct gtcattgaaa cggaagaaca gctacatgtg
     1201 ttagggaaag tactggaaca cgaaagtcga tcttctgtta agttgactct cacgttacat
     1261 gacacagaag gaaaaataga gaaagctggt acagaatacg tttttggccc actggattat
     1321 caaatttcag aaggtttcta tcctacattg atggatttaa tccgccttga tgtgtttaaa
     1381 gaaacggatg aaactatgag tgtggaagag tcttatcgaa acgaaaaact tttacaagtt
     1441 ttagaagaag agttagagag cgaccaaaga aaagtgaatc aagggagtga agtcgaagta
     1501 aatgaagaag taccatggga acgaccaata tttccaaaga aggagtcaaa agaaaaagag
     1561 acagtctatg ttgacgaaca agctgatatt ccgactcaga aatcgatatt tgaggaagag
     1621 aacgatgtga tgggtcaatt ggaggtagat ccctttgaag aaacaatgga ggatgaagag
     1681 acggccgaag tagaagttga tccagttgaa gcgaatgaag agtcaacatg gactgaaggg
     1741 gattctcagg aatatattga accacttatc agtgaagaag tagaaaaaaa cgaaatagag
     1801 atacaaaagg caactgtatt tgattatatt ttggatcaat atccgccaga gcatgaatgg
     1861 atgaaagaaa aaaacaaatt atttttaaat gagctttatt cgaaatatca attaccccaa
     1921 acctatcaag catttttaga gagtaaagaa gaattaatct cacagggtaa aggcacactt
     1981 ttagaacagt tagagtctgt ccaatcaaca aattggcatg agcttgcaca agaagattta
     2041 ttagccacct ttgaagaacg tcaacaagaa acagatcaag aaattaatga gtatgcgacg
     2101 gaacagtcgt ctaattggga gaaagcaaaa gaggaactaa ataaagaaga acagcgagtg
     2161 attgaagaag aagtacaaaa aattaaagag cgatacgaaa agaaacgcga caatgcgtat
     2221 tccttgtgtg tagcaaagat caataatttt actcagacga atcaagaagc gttatcgaaa
     2281 gaaaaagaaa acttgttaaa agaacgtatt aaagaacgaa aagaagaatt ttaccgaggt
     2341 ttgcgtacag ataagctaaa gattagcaaa gaattaaatg aacaactgaa taagctatat
     2401 caaacaacga ctgaagttct tatggaaaaa tacgaaaaga tccagcaaga attacaagtg
     2461 caaattccaa aatggaaaaa agagtatgaa attcaacaac aagaattgaa agaacaagaa
     2521 gaaaaacaac ggcaaaaaga aaaagagcgc gaacaattag aactaaaaaa acgtgaacag
     2581 gatcttgcgg aacaacaaat ggcaatagaa aaacaacggt taaaccaaga aaaggaaaaa
     2641 gaagcagctg ctcgtaagga acgtcaagaa caaatggata cattgcgaca agctcagtta
     2701 aattatctag cacaacctca accaacgcct tcagtagctg ctgttcaaac cccaatgaac
     2761 aaccaaacaa atctaactcc ttcaccacag cgttccttta acggatggat ggtgggatgt
     2821 attgcaagtt taagcttgct tctaggtgga ggaacagtat ttgcttttaa tcatatcaat
     2881 caatcttcac aggctgattc tgtggccaca acgacgtcaa tcaaggaaga agcccaagaa
     2941 caagcaagaa aagagtatga acaacaatta gaagaattat tgaatcgtac caatcagtca
     3001 acaacagagt caagcatgga aaatagcaaa gagagtgatt ctagtaaggc taaagaagga
     3061 tcaagcgatt caactgtaca atcaaacact tccgaaagtt cagaatcaaa tgaggtgaaa
     3121 taatgcgtgt tagagaaaca acgaagcgaa aagacaaacg attcaattta gaaaagaata
     3181 ggtatctttc tcatttctat cgctatactc cctcaggaga agagctacca gaaaaacatg
     3241 acaaacgcat ttcgaaaaag attttttata gtggacttgt atacctccct ttagagtatt
     3301 tagtaacaag agtaccagaa gttttcaacc gattggaaat tgttaaggga agcttacaag
     3361 gaataaatct gtttcaatta caggaaatgc cacaggtctt tcattttgat tcagctggtt
     3421 tttggaatcc atttactcct acaactagtt tgggtacacg tttagcaatt tcgacagttt
     3481 gtgtggttcc agctgtactt atgggattga aaatggacat gtggtttcgt cctctagcag
     3541 atggacaaaa aggggataat cgattaatga ccttaaaaga aatccaacag atttatccgc
     3601 aaatacctga aacaaaaact acttttccag gttatggagg tattccaatc acacattaca
     3661 aaaaatattg gtacattcaa acagatactg ttaatacgtg tattgttggt acctctcgat
     3721 cagggaaagg tcagattgaa gtgttagcca ccattgacaa tttatctcgt gcagaaaaac
     3781 aaagttcaat ggtcgttaat gatccaaaaa cagaattata tgttggtagt aaagatgaac
     3841 tagaagctag agggtatgat gtatatgcct ttaatatcac cgatccactg caatcaatga
     3901 gtgataatcc attggcactc atcgtgaaat actggaaacg aggagacata gatactgcaa
     3961 cacagttaac caatactttc acaaatacga tttattatga tgccaacgct tcagataaca
     4021 aatactttaa cgaaaacgcg cagaaagctg tcaatgcgct tatttttgcg ttgttagaac
     4081 aagctgatca aacaggagat tactccaaat tgacaccgaa taatctcgtt gagcttcttt
     4141 ctgagattgg cggttttaat tattatccag atccagacaa tgaattcaaa cagttgaatg
     4201 ccttagatga atttatgaat cagttgccac ctggaaacat tgcaaaaaaa caatatgggg
     4261 caacgaaaat tggatctgat aaagcgaagg gaaatatttt atcaacggca atcacgggat
     4321 tgaatccatt tactctaacg aaaattgcaa agatgacttc tcaatcaacg attgattata
     4381 aatcggttgg gtttccaaaa tacttagatt tgaaattaca tgaaagtctt ttaaatcaac
     4441 gagtcgtagt agaattttat cataagggaa agaaatttca tgaagaacgt gtcaaagtag
     4501 gctataaagg attttgtgaa atcaattttg attgtcattt agttgcaggt gatcaagttt
     4561 gtttaaaata cgatcatcaa ggaaaagaat atgtggcttg gtatgaattt tctcaaagag
     4621 tattgaaaga cgaagagggt aatatcgttt atcggaaaaa acgaggagaa acccatttgc
     4681 cagaattaga aaaagaagcc gttctaacat tagatgagga gaaaagtaac ttattagtag
     4741 agtctattcg gatgcactat accgataaac caatggctat ttttatgctt acacctgatt
     4801 atgatccatc taaccatatc attgttagta tttttcttag tcagttatat aaagaattat
     4861 ctacgcaatg tgttaagact aaaggagata aatgtcaccg caggattcat tttattttag
     4921 atgaatttgg gaatatgcca ccaatggata atatggaagg aatcatgacg gtcacagctg
     4981 gccgaaacat gttgtgggat ctgtttattc aatcttatca gcaactttat gcgaagtatg
     5041 gagaacaaaa cgcagcgatt atcaaagaaa attgtcagac acatatttat attatgtcga
     5101 cagatgataa taccatcgaa gaattttcta aaaaagtggg gaataagacg gttgaacaag
     5161 agaacagtac catcaattca ttaggtatga atactcatat caatcgcaat gttgattcag
     5221 atcgtatctt aactcctgaa agaatttcta cttttttaga aggtgaaacg attgtactcg
     5281 ctcctttaaa acgacaagat ttgaaaggtc ataaaatacg gccgtatcct atttttaatc
     5341 atggggaaac gaatcttcct tatgcttatc aatatattga agatttcaat ccatcgtggg
     5401 atatcaatga tatagacata cattgtacac atgcggactt ggatcttaag gctttacaaa
     5461 ttgattatga ttatttccta ccagatgaat atgctagaaa tctctatcat ggactgcatg
     5521 atcaattaga agaaaaaaac gaagaaaata tgttttataa aatcgttcaa tctcttgaga
     5581 atgagacggc taaaaaattg ttaattcaat tttacgaaga acaagcagca gatcgacttc
     5641 aagaatatgt tgaaaagttg atcaaaaata aagaaatttc tgaaatgatt gggaaacggt
     5701 tgttattgga atctgaaaag gtggtgaaag aatgatcatt ggaggaattt tttctggcat
     5761 agccgactgg tggtcaggct tattcggaga aggggatgca aaccccaaaa ccgtaacgaa
     5821 agtcttacaa gattatggta attatctgca gtatcaagat gtatttagtt ggatttggaa
     5881 cacttttctg tggggattga ttaaaggatt atataatctc aatactttac tagaaaaaac
     5941 catttatcaa agctttgatt taaaagactt attgaacgcc gctggggtaa atgcactatt
     6001 tcaaagtttg attagtaagg tattggctct tttttgtgtc gtcacattaa tttatttagg
     6061 cttgaaattt tttatgagta aacacccacc aaaagtcaaa aatatcttgg ttaatttatt
     6121 tatggccatg atcttgattt ttggtgggag ttctttaatc gatgaagggt taaatatcag
     6181 taaaagcttt tacggagacg tcactgcagc aaataaagca gataaaacgg gttcacctgc
     6241 ttttcaaatt attcaaaata atgtgatcga tgtcagtaca ttactagcaa ctgacccgaa
     6301 taaagtagaa tccctgccaa cagacaaaag aaatgcttta acagcgaaaa attttaaaac
     6361 agcgaatatc aatgggatta ttactcctaa acaagctaaa gaaatggcgg ataaagataa
     6421 gagtggttta tcagatttac aaaaggatcg gttaagagcg ttacaatacc gattggaact
     6481 agatgataat gggaaagaaa ttcctgttca aattagtgac gaaggcttag caaaatatgt
     6541 ctatacttca gggtatcgtc gatacagtag taaaccaggt attatcttag ctggtgaatc
     6601 ttctttggcg gtggcctatt tatttatcct atttacgatc gttacttgca ttattgagct
     6661 ggtatttaaa aaattctatt tagtgattgc cgcgtcaacg gactttgaga caggccaacg
     6721 gatgaaaagt gcgatagaag atatttctca atccttcttg ttattggcgt ttacgatttt
     6781 agaattacga atctatacat taatgctttc aggtatcggt gatttgcatg cggcaggaaa
     6841 gatcaatgga ttcttgtatg ttgttgcttt aattgtgcta actattgcgc tattcaaagg
     6901 ctctcaatcg gttacgaaga ttttcggtgt tgatacgagt ctgaaaaacg gcagtaattc
     6961 tcttcttagc atgtttgcct taggaaatat tgcgaaaaat gtgggtagcg gagctaaaaa
     7021 ccttgcaagt gctggtaaga gtggtttaag ccatttaaat gatattcgta aaaatggatt
     7081 tggccatcga aaagatgtta cccctgataa cggggaagaa caatcagacg ataaagctac
     7141 aactgtacct aatagtaaga aaacagtttc cgaaatgttc gggaaagcga aaaatggtgt
     7201 ttctaaagcc gcagaaggtc ttggttacgt caatgaacgt gggttaaaag gaacagctga
     7261 agatcttaca gaaaaagcca aagacacctt agaagagaaa ttagacggca cgagagctaa
     7321 agaattggct gaagctgtga agaatccatc cgaagcacta gaaaaacaaa aagaaaaagc
     7381 ttcagaagtc aaagaaggac taaaagatgc gtatggtgaa ggacaagtta atgcagcagt
     7441 aaaagctaat acaacaaccg aaaaagaaaa tcaagaaggt atagtgattc cttcagtcaa
     7501 agatcaccaa gaagcgttgc actctaatga aaattcgatt gaagagaaaa attccataga
     7561 agaaagaaat tcagaagaag gaaaaaatgg acagttacca aaaactgatc cagaacaata
     7621 tcgctataaa cctaacagtg accttgaaaa tgagaagcga atttcagatt tatcaaaagt
     7681 aaatcaagaa gacaaagcag aaaatgaggg acagttacca aaaactgatc cagaacaata
     7741 tcggtataga tctgttaact ccgaaaatga aaaacgcatt tcagatttac caaaacgaaa
     7801 tcaagaagta caaacggatg aggattccat cgttctgcca aatgataatg gaatcgaagt
     7861 tggaactgaa aaatcaacga aaattggttt acctaaggca caaaatttac caatgaaaga
     7921 tagtcgtttg aatcaattca aggagaatga tcaaagcttt gttcaccaat caactgcagg
     7981 tactgttcaa atgaaaccaa gtcgtttgcc tgaaaatgga aatctgacaa ctgtttctta
     8041 caatttatct gaaagtggtg agacagggaa tgcgtccgtt caaaatgttg tgacaagaga
     8101 agctgcacca aaacctattc aaaacgttca tacaggttac aagccagcaa atgtggcatt
     8161 tactgcacca acaaaaataa atgtgacaag agaaactaaa aacaggaaca atgcattgaa
     8221 agaacaacta ttgagggata tcaaacagga tatcaaacca taaaaggcct acaagttagg
     8281 ccttttattt atatgaaaag gagaaatcaa ttatggataa atatataaac atgaaaaacc
     8341 ctccaagatt tagtggagaa tggaagtttt tcgctttttt ctttttagat ctattaacgc
     8401 ttggtggctg ctttttttgg gcgaaaatgg tcaataatct tgtccactta ccactctttt
     8461 ttgcactctt gaattatggc ttatggattg cgatagcgtt agtgattgtt tggcgaccct
     8521 ataataaccc aggtcaacga caaatttttg cgattatcga gtctattttt tttgcggaca
     8581 agaaccatta tcatgcgtta gatcctaacc gaaattatca tggtacgtat aaggaggatg
     8641 aataaatgcg agtcaaagga caaaattcag ttgaaaggaa atccattttg cagtttggaa
     8701 aaccagaaga gcgctctatc ttggacttat ttccgtataa atcctgtaca gaagagggag
     8761 tcttaattac tagagaagat cattttcaac gttattatcg tgtagtttct acagacgtgg
     8821 aaggattaaa tgaacaagag aaactagaac gaatgaatca gttgaccacc gtcatgcgta
     8881 cgtatgtgcc aacaattaag ttagttagtt tgaccacaga gacggatcta acggaacaaa
     8941 tcgtgcaaaa gcggcaatta ttagataaaa atcgtatgga acagtcctta ggaagaaatc
     9001 tacaacgatt aaaaaaatat gaaaagaaat tagtcgaaga aatccaggaa ttgaaacgag
     9061 cagaacaaga acgtcctgac ttaagcttct ttttcgtcat tgaaggaaag acaatcaagg
     9121 atttacaaac cagaaaccgt cagttaatgc gatctagtgg cattttaggg ttaaaaccac
     9181 tctacaaaaa agaattgatc aagattctgt atcgaatgaa caatatgaat gatgagtagg
     9241 aatggagaag agagaatgaa atatccgttg atatggttag aaaaagatgt tccgaaggaa
     9301 gagaccacta gaaaatttcc tcacacttta agcctgggta agttgggaaa agggcaatct
     9361 tttaaccaag taaagaatca aacaagaaga ggtgactgta catgttagaa gcaattaaaa
     9421 cagctttttc accacaaaat gatcaaaaag tacttgatcc attaaagcaa ctaggaaatc
     9481 gggaaataga aattttaaaa tccaaagggt atgatttaga ttttttaaaa caagtgatgc
     9541 cacaaggtgg gttaaatttt gatgaagaat atgtgacgta tggtaatggt tattcacgat
     9601 gtgtgacagt ttatcactac acaaaaaatc ctacgctttt ttggttggcc aatctcatga
     9661 acaatcctca tacagtggcc acactcgatg ttagcacaga tgaaaagcaa aaagtgattg
     9721 atcaaatcaa tcgtgcctta gatgaattaa atgatcgatc agataatgaa cgaaaagcga
     9781 ctgaccgaaa taaaagcgca gaagaatacc tggaactagc ggaatatgct cgtaaattga
     9841 cttctaatgg ggaaatttct aagcaagtca aagtgagagt acatgtttac ggaaacacga
     9901 ttcaagaagt agatgaacga gcgcaggaac tgatcgaaaa tctaaaaggg atggattatc
     9961 gtgcggtgac ttatctgcat aaaaccaaac gagattggca atcgatgttt accatgttcg
    10021 atgaacaagc tgaatggttc ggaaatatca aagggcaatc actaccatcg ttaaacattg
    10081 gcggaggttt cccgttccac caccaaacgc taaaagatcc aggagggaca caatatgggg
    10141 aaaccatgac aggcggccca tttgtctgga atgcgacgta taaaaatagt gtacggttgt
    10201 ctactaatac cttgcttcta ggaatgatgg gagctggtaa atcgaccgtt cttaaaatga
    10261 tcgcggaagc ccatttagct gcaggagact ttatttgggg ctttgaaaag ggaaaagact
    10321 ttattccttt cttaaaggaa tataacggta ttatggtgcg tttagacgga tctgacggaa
    10381 tgatcaatcc tttagagata tttgccacac ggacgtatga tgaagcatcc agtttatatg
    10441 acgatggatc agtcaaagat ttgaagatca atgaagcagc gtcctatcaa acacacttag
    10501 acaaagtggt ctatcaggta cagttagtga gtcctcagct aaaaggaacg atgaaagcag
    10561 aatttaagac ctacttaaat cgtttttatg aagagtatgg aacagtacca cgcggcttta
    10621 cttcctcaaa ttcgcgttca aatacggaga cgcaagtcac aggtaaagat ccagaagctt
    10681 atccgacgtt caaagaattt ttagactttt taggacaact ggaattacca ggtgcttccc
    10741 aagagaaaaa gaatcgaaaa gaagaaatgg aatccatcgt agaatcctta tgtgagacgt
    10801 atggcatgat ttttgatggg catagtacga ttcgacacct tgaccaacaa cagttggtct
    10861 tttttgacat tgactctatt acaggcttag atcgaggggt acaacaatgt caaatgtaca
    10921 tggctatgac gttgatttgg aatcaggcat tgattcaagg aagaagacaa cgacgtttaa
    10981 ttaaagaaaa acaaatggaa gaacaagact tcaaacgctt cttggcgatg attgatgagt
    11041 gccataatgc gattaatcca gattttattg aaacggtaaa ttatgtcaca aactttcaac
    11101 gagaaatgcg taaagtagaa gcaatgactg ttttagctac acaatcccca caagaaatgg
    11161 tgccagaaaa tatgtcttct gataacttct cgaaactgaa gaaagtcttt gaattttctt
    11221 ctacgaagat ctttatgcgt atggatgaat ctattttacg tcatatagaa ggattagtgg
    11281 gtaaatcaat gacgaactca gaattagaat ccattcctca acaaaatcaa ggagacgctg
    11341 tgatcaattt tggctcaaaa gaaaccattc gtgttcattt tagtccgaac aaacgtcaat
    11401 taaaattgtt tgatggagga aaataatgga aaaccaaaat ga
//
LOCUS       DACGEU010000088        11332 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.089, whole genome shotgun sequence.
ACCESSION   DACGEU010000088 DACGEU010000000
VERSION     DACGEU010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11332)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11332)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11332
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.089"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            226..894
                     /locus_tag="IXR40_002289"
     CDS             226..894
                     /locus_tag="IXR40_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HAQ4362101.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
     gene            complement(1094..1324)
                     /locus_tag="IXR40_002290"
     CDS             complement(1094..1324)
                     /locus_tag="IXR40_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362102.1"
                     /translation="MTLQEIDSILTEAFLSRKAVIIQLNLKDEFGRLLDEVEGHFIGE
                     AYEDYFMIDHQPILWEDVRYIELKETKKWFVT"
     gene            complement(1451..2833)
                     /locus_tag="IXR40_002291"
     CDS             complement(1451..2833)
                     /locus_tag="IXR40_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HAQ4362103.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            complement(2989..4176)
                     /locus_tag="IXR40_002292"
     CDS             complement(2989..4176)
                     /locus_tag="IXR40_002292"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HAQ4362104.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            complement(4183..5214)
                     /locus_tag="IXR40_002293"
     CDS             complement(4183..5214)
                     /locus_tag="IXR40_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HAQ4362105.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGRFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            complement(5260..6684)
                     /locus_tag="IXR40_002294"
     CDS             complement(5260..6684)
                     /locus_tag="IXR40_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAQ4362106.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANAATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMED"
     gene            6859..7764
                     /locus_tag="IXR40_002295"
     CDS             6859..7764
                     /locus_tag="IXR40_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAQ4362107.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            7855..8532
                     /locus_tag="IXR40_002296"
     CDS             7855..8532
                     /locus_tag="IXR40_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HAQ4362108.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            8813..9709
                     /locus_tag="IXR40_002297"
     CDS             8813..9709
                     /locus_tag="IXR40_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAQ4362109.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(9764..11134)
                     /locus_tag="IXR40_002298"
     CDS             complement(9764..11134)
                     /locus_tag="IXR40_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAQ4362110.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
BASE COUNT         3607 a         2220 c         2208 g         3297 t
ORIGIN      
        1 cgtccaattt cgtaaaacaa ccgtaacggt tgtgtaaaaa tatcatttta gagcataaaa
       61 aaaaggagtg gatttctcca ctccaaaaaa gtctaacttt tgggggtcac tacagtgtca
      121 cagtcctttt tttagtaaaa ggatacattt cttccttgta tattccatgc gtgttcgtga
      181 gaaagcatat ataatttaat taacagatag ttagggggag aaaaaatgat tttttcaatt
      241 acaatgaaac tggtgttcgg gttgatcggt ttattattag tggtacgttt gcttgggaag
      301 aaatccatgt cagaaatcac accgtttgat ttagtctata cgcttgtttt aggtgggatc
      361 ttagaagaat caacctatga tgacaatgtc catgtagggc atgtcctatt tgccattgcg
      421 ctttgggcag taatgattta tggtatcgaa cgtatcgtcc aaaaaaatga aaaggtcaat
      481 cgttgggtca aaggcgagcc atctgttcta atcaaagacg gcgtcatcaa catgacagag
      541 ttgacaaata accatatcga gatggagcag ttgcgagcaa tcttaagaca gcaagaatgc
      601 ttttttcttg aaaatgccaa acatgttatc ctagagaatg ccggtcaaat gagtgtattg
      661 aaaaaatcag atgaagacaa agctttatcg atcctgcttg tagatgaagg gcaaattcag
      721 cataaagtgc ttcagtccaa tcaattgact gaagcatggc ttatggagaa cttgaagaaa
      781 gaaggctatg cagatgtaaa acagctgatt tatgttgaat ggtcagaaga aaaagggctc
      841 tacatactaa ataaagaaga cgtcatgcat gaatcttacc gaatagatgg atagatagac
      901 agaggttgtg aaatcagcgc cttggcttgt tactcaaaac taagcgactt tttcacaacc
      961 tctgatatct aatatacgtt gttccagaag ttgcttcttc gaaaaataag ccaaaattcc
     1021 acaaaaattt aagaagcaat tttcgaaaaa tcctttctta ttttttgaag ttgatcactt
     1081 ctgtcacaac ctctcatgtc acaaaccatt tttttgtttc ctttaactca atataccgta
     1141 cgtcttccca caatatcggc tgatggtcaa tcataaagta atcttcatag gcttcaccaa
     1201 tgaagtgccc ttcgacctca tccaagagtc ttccaaattc atcttttaaa ttgagctgaa
     1261 tgattactgc tttacgagat aaaaaggctt ctgtcagtat actatcgatt tcttgcaatg
     1321 tcatttgttg tttaggaaga ggctgtttgc gtgcttcttc ttcatttttt tgataccgtt
     1381 gactagttct tccatcgcaa aagcagtccc ccattttaat ccaaatggcc gatctcgata
     1441 ctcgttatag tcaatgaatt tttttgctgt ccgtctcatc ttttccacct tctaatccac
     1501 tcataccacc tgcatgcccg ccaacgagag aactacgtgc gatggcgcgt cctccttgca
     1561 agagactatg cgcatggatg attgattgaa agccgtattt ttttctaatc gtatcgacaa
     1621 caaaatcaac tttcgcttca tttatctgct tttcaggatc ttcaaaaagg ttaagctgta
     1681 aacctgtcgc gtatacgagg tcggaacagt tcacgcctac acgccgaata tcctggtagt
     1741 ggtaatgctg gtggaaaatg gtcaataaag catctgcaag atctctgcta gcatttgtcg
     1801 cttcgatttt catttgctgg tgaaacccgg tcttgccatt tggatcaaga tagcctaaag
     1861 agtatcctac ccataagctg actacttgtg tttttgctgc agatcgtctc aagcgagtgc
     1921 cgacttggtc ggccatttct ttgataacga tctcgatttc ttctcgtctt gtataatctc
     1981 tatctaggat ttgactattt ccgatacttt ttgattttgg tgtatattct tgtcccaaaa
     2041 aacttcgatc gatgccccaa gcatgggcat aaagctgagt accgatgacc cctagcttgc
     2101 ttttcaagtg ataataatcc gcgtgagcta aatcataaac agaatgtata cccatttgtt
     2161 tcagacgttt tgctgttcgt ttgccgattc cccaaaagtc agtgatatct gagattttcc
     2221 ataacttttc tggtacatct tcataacgcc attcagcaaa catttgcttt ccgtcttttg
     2281 agccattgtc taaggctagt ttagcaagta gcgggttatc gccaattcct atagtcgtgt
     2341 agattccggt ctgctcaaac acatctttat ggatcagttt agccatgtcg tacgcatttg
     2401 ttttaccaaa gagtgccatg ctatttgtta catcaaggaa gctttcatcg acggaataga
     2461 catgatggtt cgcttcgtct gcatattttt tatagataga attgatttct ctgttctttt
     2521 ccatataata ggccatcctt ggggcaacaa tatataaatc acttggatag gggaagggaa
     2581 gatctctggc acggctgata ttggtgatgc cgtaagcttt ttttgctgca ggactggaag
     2641 ccaagattaa tccgctaccc cgtgtttctg tcgaatcgga cggataggac atgactacta
     2701 atttagttgt aaggggatca agatcctttt caacgcactc tacggaggcg taaaaagatt
     2761 tgcagtcaat acataaaata tctcttgaag gttctttttc ataaacaaat accggatttt
     2821 gattcgccca cataacaatc acctcttcaa cacaattaga acacacgttc tctttccgtg
     2881 tcaataaaaa acagcaattt tcaaatacga gcaaaaggct cacatttgga aattgctgag
     2941 aggttatttt tatctatttg tttttagctg agatcgttga tttttttatc aaacatgaac
     3001 agcttctgga tcgatctttg ttgtcccatt tccaatgtgt gcaacataaa attccggagc
     3061 atagccgaca actttcatgt attcatcata gacattgttt ttgaaggcag gtatattttc
     3121 ttctttgaca agagcaatcg cacagccacc aaatccagct cctgtcattc gtgcacctaa
     3181 gacaccttct tgtttttgag cagcatctac tagtgtatct aattcgatcc cagttacttc
     3241 ataatcatag cgaagagagt ggtgagaatc atttaacagt tgaccaaatg cttctaagtt
     3301 cccagcttct aattcagctt ttgccttcaa agtccgctga ttttcagaaa cggcatggcg
     3361 agctctgcgt atcaatgtat catcgccgat ttggtcaata gttgattcaa attcttcttc
     3421 atctaagtct cctaaagaag agataggcaa agttttttgc aaacgtgcca aggcttcttc
     3481 gcattcgcta cggcgttcat tgtattttga atctgccaat tcccgccgct tattcgtatt
     3541 catgatgacg attgcataac catctagttt cactggaacc atttcgtatt tcagcgtatt
     3601 tgtatctaat aagattgcat gatctagctc accgaagccg atggcaaact gatccatgat
     3661 acctgaattg acaccgatga attcattttc tactttttta cctgtttgga ctagttccaa
     3721 gcgatctgtt tttaaatcaa acagatcttc taatacaaca cctactaata attctaatga
     3781 agcgctactg gaaagtcctg caccattagg gattgttcct tccactaata actcaaaccc
     3841 atgatcgatt gagtgtccag cttcttttaa tttaaggacc attcctttta cgtaatttgc
     3901 ccagtttgct tttttatcat attctagctc atctaaagta aaactaatga caccgatatc
     3961 gtcaaagttt gtggaataaa ctaatatttt attatcgtct cgaggtgctg ctacaccttg
     4021 cgttccataa gtgatggaag cggggaagac atggcctcca ttgtaatctg tgtgttcacc
     4081 aatcaaattg atgcgtcctg gtgagaagta ttgtgtagtt tttttaggtc cgaatgtttc
     4141 ggcaaatttt gtgtttaagc ttcttttgat ttccatgatg agttattcct ttcttgtttt
     4201 gattttgaat tctgttactg tttcaaatac tgatccggct tttaaatgaa tcgaaccaaa
     4261 tgctgagaag cgctctgcac ctggagctgt ttgagtctca aatgtgatgc caccgtgatg
     4321 tgccagtttt cggttgcgca tttctggtgt ttctgtgccg aaatttgcag tgaaaataac
     4381 cacactagaa gcatctgtag caatatctac ttggattctt ttatcggggc tagtcaagcg
     4441 agcggcttct ttacccaagc cggtttcttt taagaaaaat ggatgatcga ttccgtcaac
     4501 aagatttttt tgatccaaat cactagcaaa aacggacgct aattttttag gtatttgaaa
     4561 atcgaaagca cttcctgcag cattttcttt tacccctata ggaatactat ctgttcgcaa
     4621 aggagcataa gcttcgctat tgagccaaag ctcatgttga tcgattgact gagaagcatc
     4681 tcccgtcaag ttgaagtaaa catgatttgt cggattgaat aaagtatctt ggtcactggt
     4741 gccgcgagag gtcactcgcc agatattatc ttttgtcaaa gtatagcgga tttccacatc
     4801 cattgtacct ggaaaaccat gttctccgtc gggacttgta gtagtaaaaa tgacagaagc
     4861 ttcattttcg ccattcaaaa tgacataaga ccattttttt aattcaaatc caggagcacc
     4921 accatgcaga ttatgtccag tttttggatc tgtggctaat tggtaagttt ttccattgag
     4981 agaaaagcgg ccattttcga ttctccctgc ggtgcgaccg atagaagcac cgatatacgg
     5041 atctttttcg atatattctt cagcggtgtc aaatcccaaa actaattctc gatcatttga
     5101 ttttaaactg acgattctag cacctaaatc agagatagaa agtgctagct tgtttttgtt
     5161 ctccaaggtt atcaagtgat aaccttggcc aaaatctttt tctgtaatct tcattttcaa
     5221 gatcctttct taatgggaag gaactactgc atcgtgaagt taatcttcca ttgtatcagc
     5281 tggagccaat ttgttttcca atttctcaac gatttgtgca tgttttttct ctgtcaatgt
     5341 aatcttccaa gcaaaaataa tagcggagaa aatcatcaaa gcagcaggag catagaatgc
     5401 ataagctttg aaagtcgtta cgccatgagc agtgatatca gcagcagtag cattaccagt
     5461 catcccagaa gcgatagcga caaaccctac gatcccgtta gacaaagcac cagcgatttt
     5521 atctagtaaa gggcgaattg atagagtaac agcttcgtta cggataccat ttttccattg
     5581 accatattca acagagtctg tgatcgtcat caaagcggat aagaaaatca attgttgagg
     5641 gaagtagaac aatactagcc cgatgataac gattggcaaa cttgaacctg cgatcgtaaa
     5701 gaaaaagtaa gaagaaatca tcattgcgat ccctccaagg taaacgtagc gacgagagat
     5761 gacgcgtgta agcattggga atagtggaac agctactaaa ccaagtaagg cagcaactag
     5821 accaacgatc caaaattcag ttggttggcc aagtacatat ttgaagaagt agaataatac
     5881 ggcagttgtt gctgcattgg caatcgcata agcgatataa gcaagggcaa gccacatcaa
     5941 ctgatcattt tgagcaactg ctttgaacac atctttgatc ccagcttttt cattttgctg
     6001 acggatcgca gtatcgactt cttttgtgcc caaggcagtg ataatcgcag taccgcctga
     6061 aataacagca gcaatcacac cgaaccagaa ccagcctgaa gcgccttcaa tatgtttatg
     6121 agtaacaaga taggtaaaga aagtaacgat agggacaacg actagagtag taccatttgc
     6181 acctagagaa gagccgaaac gagcaaacgt agcaaatttt tcacgttcct ttgtttccgt
     6241 actcaaagct ggaatcattg accaaaaagc gatatcctta aatgaataaa aactatccaa
     6301 taagatgaaa acgattgcaa ataatatgat aaataaagtc gtattatgag tagctaagcc
     6361 aaagaaattg gtaaagattg ctaccaagag tacggaacta acaacgccgc cgataactaa
     6421 ccatggtttg aatttaccgt attttgtacg agtattatcg atgatgccac caatcaaagg
     6481 atcaaaaata atttcaacta agcggatacc tacaactaag cttgtaactg tagcaatcat
     6541 ttttgcattc gttgccttat ctgttcctgc gaacatctgg cttgtcacga ataccataaa
     6601 ataagtgctt aatgtaacat agaatgtgtc gtgtccaaaa gcgcctaaag cgtaggacac
     6661 acgttggatc attttgcttt tcataatctg tattcctctc ctgttcaata tataatacta
     6721 agtaaaccgg ttacaacgaa taacaaagat cttttaatga cttaaactta acaagaaatc
     6781 gcttcctttt taatatattt ctgtgacttt tatttaactt tttgttgcat tatactaaag
     6841 gagtaaggag ggatagacgt ggagcaatcg atttttttaa aaaaggaaca tcaacaagta
     6901 gaaaaagaat tgtattttga tttttgtggt ttctctaaaa cgatgccgtt tcattctttt
     6961 ggtcctgcta ttcgcaatga ttacatcctg catgtcgtga tggaaggcaa aggatcttat
     7021 catgtgaaaa atcaacaatt ccaattgaaa aaaggtgatc tgttcttgat tcgtccagga
     7081 gactcgacgt tttacttatc agatggagaa gatccgtgga tgtattgctg gctttcattt
     7141 ggtgggagtg ctgcagaaga aatcattcgg cagtcgcttt tcagagaaga ccaatacacg
     7201 atggtctctt ctgacataca aaaatatatc gacattattt tagaatgcat gaaagatacg
     7261 gaagaaacct tggaaaatga attacagtta acagcattaa cctaccgttt tttatcagtc
     7321 cttttaaaag atggcggaaa ggtcagcggt ggtgtacaaa aggttcattc ctctttagct
     7381 gttgaaacag tcaaatacat cgaggcacat tatgctgaaa aattgtctgt tgaggaaatc
     7441 gcccagcatt tagcggtcaa tcggagccat ttgtcgcgag tattcaaaaa tcatatgggt
     7501 accagtatca aggaatattt gatcggggta cggatcaatc gaggggcgtt tcttctttct
     7561 ctgacggatg aatccgtgga aagtattgcc tatcaagtag ggttcaatag tctagtcgta
     7621 tttagccgaa tgttcaaaaa gagtaccgga gaaacggcta cgaactatcg taaacgtatg
     7681 aaaaacgaaa attttaagaa tattgctttg gataccttga aaaaacagtt ggaaaaacaa
     7741 accgcagttt cttggacaac ctgattagtc tggttaaaat gacaagcatc ggcaaaagaa
     7801 acttgtggcg gttatgctac actgtaaagc gaagactaaa aaggaggaaa agggatgcgt
     7861 acacttatca tcattagcca tccaacgatc gaagaatctt taaatcagca atttttcaaa
     7921 gaagcttctg ctggtttacc agctacttgg catcatttgg aatcaagtta tccagacgga
     7981 aaaatagata tagagactga actacagctc ttggcccagc atgatcggat cattttccag
     8041 tttccgtttt actggtatag ttctcctgct catttaaaaa tttggcaaga taatgtcttg
     8101 gaacgagcag cacatgtatt aaaagggaaa gaactaggaa tcgtattgac aacaggtgtg
     8161 gcggaaaaag aataccaagc tggaggaaaa gaagaatata cgatttccga atttttgagg
     8221 ccgtatcagc gaatcgcaaa taaattccat atgacctatc ttccgccatt cgttttagca
     8281 caatttatgt atttatccca ggaaaaacgt tgggagaagc taattgctta tcagcagtat
     8341 ctctcattgg aaggcaaacc atcgctgact cagcggattg actggtttat tcaaagagta
     8401 caggaaaatc agaaaatgca ggaagaagaa tctgaaaaac aagcatatat cgtagaagca
     8461 ctgactgagg caaaagagca gatcgaagac ttgaccttta cactgcaaga aatgaaagga
     8521 acttcattat gacaaatgat tggctgatcc aacaattaga tgaattaagc gaaaaatcag
     8581 aatatcaaga ccgtgcgctc ttatatgaaa taaagaaact gatggctgag atagacgaac
     8641 gaacaatgca gctgcaagga gaaatcgacg gacaatcttg gaatcatctc aactggtgaa
     8701 attttcttat aaataacaaa gataaaaatg tgcacagcga caattatttg ctacaataag
     8761 aatatgaagc gtttgataac gctattatac ataaaaattg gtggtgaaaa aaatgtatga
     8821 tgaaaatgag tggggagaaa atgttcggat gacccgaaga agacagcaaa aacaggcagc
     8881 tcgtaagcgg atgatcatga ttggggcagc agttgccgtg tttttgatca tagcaggagg
     8941 agttgcgggt ctatattttc atggaaaaaa ttcgtcagaa gcgaaaagta cgaccataac
     9001 ggaaacaacg acaaagaaaa cagagacgaa acaaacaagt gagtcatcaa ctaaaacaaa
     9061 agagacacaa acttctgaag aaaaaacagc aaatggtttg ccagagcaac ttcaagcaat
     9121 cgtaaatgat tattcgaaaa agatcgaaga aaagacgcct gcattgattg aagaatacca
     9181 gacagaaatt cagggaaatc aagagggaat agctggttta tcagcagttg ctaaccaaaa
     9241 agcacgtgag cttcaagcaa tctccgacga agggatcaga aaattacgtg cagcgtatca
     9301 ggcagcagaa aataaagacg gtgtagactt agatactttg atcaatcaat tatcggctaa
     9361 ttatacgaat catgtcgcta agatttccga tatttatttg cagactagcg cctctcttca
     9421 agcagagtca acaagcacac aagacacaac atcttctgat tctgagacag cagagtcggt
     9481 agaagcttct gaaatgcaag ctcgaacaac acaagacaca acagattcct ctgaaactaa
     9541 taccaacagc gcgacttcac aggctgcgac aaccgtagtt ttggaaggag aaggtccaaa
     9601 tcaaatagcc gaacgaactg gcgtaccagt agaaacgatc ttgtcgctga atgggatgag
     9661 catggagaat tatttcctga ctcccggtga gacgctaaaa ttgaattgat aaaagcaata
     9721 aaaaagaacg aagcttccac taaggtgaag cttcgttctt tttttatttt ccggttcttt
     9781 tttcgcgtac aaagtaatgg atcgtcatgt aaagcaagaa aacgagtcca ataatcaatg
     9841 agattctcgt ttcaggattg ataaacatga aaatcaatac gatagctaaa aaagcaagtg
     9901 tcacataatt cgtataagga gatagtggca ttttaaaagg atgatcatgc attttatctg
     9961 cgtgcttctt tttgaagcga atctcgctga tcaaaatcac tacccaagga accataccag
    10021 gcaaaatact tgagctgtat acgaaaacga aaatattttc tgactggttg atgaacattg
    10081 gtagaagata atttaagatc agaccaatta agattccacc tgagattgct acgacaggat
    10141 aaaaaggcgc accgtgacga gatagtttca gaaatttttt agacatcttt ccatttatgg
    10201 caagtgtata gaccatacga cttgcgctga aaatccctga attgcaacct gataatgccg
    10261 ctgtaatcac gacaaaatta atcagtcctg cagcaaatgt aatgccgact ttagaaaaag
    10321 tttgtacaaa aggtgaacca atctcactca attgattcca cggatagata ctcacaatga
    10381 taaaaatagc accaatataa aaaatcaaga ttcgaccgat agtggactgg acagcttcaa
    10441 tgatcgtctt tttaggattc tctgcttcac cagcagtcat tccgatcagt tcgattcctt
    10501 gataggaagc aacaacgatc gataatgcaa agaaaaatcc tttgacgcct ccagtgaaga
    10561 atccaccatt tttccaaaga tttgaaatcc ctactgcctg accatgatta ccaaatccaa
    10621 ataagattac cccaagacct gcaatgatca tcaaaatgat cgttatgact ttgatgatcg
    10681 aaaaccaaaa ttctaattcg ccaaacgcct tgacagaaat aagatttgcc agcataagaa
    10741 acaagacgac aatgattccg ggaataattg ccggcaaatc aggccaccaa taattcatat
    10801 aagatcctac agcaatcact tcacttattc ctacgacaat atattgaaaa atattactcc
    10861 aagcggtcaa gtagccagcc acaggatgga tgtactcgct cgcgtaattt gcaaaagaac
    10921 cagtcgaagg atcaacgtaa agcatttcgc ctaaagcacg cataatcaaa tacaaaaaga
    10981 atcctgcaat cgcataggct cccatcactg agggccctgt ccaacgtatg gttgaggagg
    11041 cacccataaa cagaccgaca ccgatcgttc cacctagtgc gatcatttgg atatgacggg
    11101 cactaagact tcgagttaac ttttcttctt ccatacaaaa actcctttcg ttgttgagtc
    11161 aacaagaaaa aataatcaaa cgtttcaaca catgtttttc attattaggt tagccttatt
    11221 gaactcttga tgtgattcta cagaaaattt tcataaaatg cgaggaaaat tcgaaaaaaa
    11281 ctttttcatc attctacttg aaaatgcttt ccattttagt taaactatat tt
//
LOCUS       DACGEU010000089        10989 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.090, whole genome shotgun sequence.
ACCESSION   DACGEU010000089 DACGEU010000000
VERSION     DACGEU010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10989)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10989)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10989
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.090"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            1..431
                     /locus_tag="IXR40_002299"
                     /pseudo
     CDS             1..431
                     /locus_tag="IXR40_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(333..1049)
                     /locus_tag="IXR40_002300"
     CDS             complement(333..1049)
                     /locus_tag="IXR40_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HAQ4362111.1"
                     /translation="MIKEKIDSFVTIDDLQVGKPDPEGYLLCLKRLRVEQAVVVEDSP
                     VGAQAAPHMTVDVQALDADFFAFSGHKMCGPTGIGVLYGKRQLLEQMEPVEFGGEMID
                     FVNLYDSSWKELPWKFEAGTPNIAGAIDYLNEIGMENIHRYEQELVAYVLPKLQAIGG
                     ITIYGPQDPEHHTGVVAFNLDGIHPRDVATALDMEGVAVRSGHHCAQRFIDDFCLTNW
                     SFKQSMIMPFERLQCRGIFE"
     gene            complement(1099..1308)
                     /locus_tag="IXR40_002301"
     CDS             complement(1099..1308)
                     /locus_tag="IXR40_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362112.1"
                     /translation="MDVLREYSSLFTEAYLLEQFGYKIPFADYQQGVGTAAELSFYEG
                     ISQAVGRPVDAEHFEQRISSTGKSE"
     gene            1585..2858
                     /locus_tag="IXR40_002302"
                     /pseudo
     CDS             1585..2858
                     /locus_tag="IXR40_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250512.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(2965..3996)
                     /locus_tag="IXR40_002303"
     CDS             complement(2965..3996)
                     /locus_tag="IXR40_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4362113.1"
                     /translation="MFLEIHDLNLFFDEKQILAIDEIQIEKGELVTLLGPSGCGKSTL
                     LRCITGLEQPKSGEIVLDNENIADKPTKDRNIGFVFQQYALFPTMTVFENVAFGLKVK
                     KLSPEVIQEKVFEMLSLVDMTEQADKNVQFLSGGQRQRVALARSLVTEPKVLLLDEPL
                     SALDARIRKQLQRDLRAIQQSLGMTMIFVTHDQEEAMRISDRIFVMEAGRVAQVSTSK
                     ELYQNPQSRFVAEFIGNYNRFEWYELNQYTHEFSAKGNRCIYYLRPELIQFEPVPQGV
                     KIPVLWKESFILGNIQRYVFQTLEGKEILVDRLNDREEKISDALYIQLKDILAIPVEI
                     DTQHFAQQS"
     gene            complement(4003..4833)
                     /locus_tag="IXR40_002304"
     CDS             complement(4003..4833)
                     /locus_tag="IXR40_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4362114.1"
                     /translation="MKKLIKPILFCFVLYYLLPIIGTILYASSTKWSKSLLPSDFTLQ
                     WFQQLLTDREFIAAVGRSLLLAGVVLVTILLLMIPTIIWIHLYFPRLNRWLEKLLLLP
                     YALPGVILVTALLRTYAETGIPMFVVLVGALFITALPIVYLSLNNQMRLINLKELVDA
                     AETLGAPMSTIIIQVLFPNIRIGVTLVSLMIFSSVFGEYMLTNLLIGGRFQTVRIYML
                     RRMNENGHLASAVMVLYLLFMVGIALTTFMLTYRQKQQLSLKQTREEKQSKKKPLKEL
                     "
     gene            complement(4830..5636)
                     /locus_tag="IXR40_002305"
     CDS             complement(4830..5636)
                     /locus_tag="IXR40_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010757330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAQ4362115.1"
                     /translation="MKKRLVLVPASFIFCAFLLLPLLFMVLCSLHSDLTNQWTLANYS
                     DIFSNKYYTQAFVNSVLIAVSSSVIGLIGTFILCLCLMNLSTKLQEKITFVSNLAANF
                     AGIPLAFSFIILLGNVGVLKMILPFLADFNLYSWWGLTITYTYFQIPLGVLFLYPSMK
                     EVKKEWLESAQLLGASSAYAWFKVALPFLRPSIASTFVILFANGMGTYETAYALTSSN
                     VNLLTIRIAALVSGDVFAKPNLGSALAVALGVLLVTAMLIIQKKGKVVQT"
     gene            complement(5642..6466)
                     /locus_tag="IXR40_002306"
     CDS             complement(5642..6466)
                     /locus_tag="IXR40_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphatase"
                     /protein_id="HAQ4362116.1"
                     /translation="MQSRLDKLIVVILDGCRYDTAVAQLGFMNHLVEHQQASLLKVKS
                     ELPSNSRPLYEVLMTGVPAYENGIYSNYHAQRSKEWSLFELVKEAGGKTGAAAYHWYS
                     ELYNQAPYNRLVDRIQHQEERLIQHGIFYSEDTYPDSHLFADAHYLVNQYQPDFLVVH
                     SMNIDDVGHKFTADSHEYAAAVNQADRLLAIYLPEWLQKGYQVVVTADHGMDAHGLHG
                     GSLAAHREVPFYLISNKRQKLKEQTVPQLLAAPLFCWLLGIAPSEKMQDIQELMRG"
     gene            complement(6456..7556)
                     /locus_tag="IXR40_002307"
     CDS             complement(6456..7556)
                     /locus_tag="IXR40_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAQ4362117.1"
                     /translation="MKMNEKIRNMTIGLFCAATVSILLTGCGSGEATKQSAAADDSLD
                     TIIEKAKEEGEIASLGMPDTWANWVGTWNDLEKEYGLSHVDTDMSSAEELAKFESEGK
                     NGTADIGDVGISFGPLAESKELTLPYKTNYWEEIPDWAKDDDGDWLLSYTGTISFITD
                     KENVKQAPTSWKELQEGDYQVSVGDVTIANQAQFAVLAAAIANGGDEKDIQPGLNYYK
                     KMAEKGRLSTVDASVANLEKGEIDVAVVWDFNGLNYRDQIDSERFEVTVPTDGSIISG
                     YTTLINKNAPHPNAAKLAREYILSDEGQINLAKGYARPIRKVELPKEVAEKLLPEDAY
                     EAAVPVEDNEAWNKTSVELPELWQAEVLTYAK"
     gene            7734..8519
                     /locus_tag="IXR40_002308"
     CDS             7734..8519
                     /locus_tag="IXR40_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol phosphate phosphatase"
                     /protein_id="HAQ4362118.1"
                     /translation="MQYYDQHLHTYFSFDSEEKFENYLAYQPEFFVSTDHFDLNNPST
                     GKDDIPDYPAYINKLDSLKETYSTKFLRGIEIGVVPGQEERIVDYLAQHPYDLKLVSI
                     HQNGRFDYMDDVVLTKDPIQTTKEYFDQMLQVLTDFPEGDILTHFDYGLRRFTFTAEE
                     FAEHFEAQLLTIFKKVVERELAMELNAKSFLKYGNEDLYRYAVPLYQSVGGKLFTLGS
                     DAHVAEDYQLGFKKMSQLLADCQVEKLLVIQGKERRLTPLPIL"
     gene            8552..8935
                     /locus_tag="IXR40_002309"
     CDS             8552..8935
                     /locus_tag="IXR40_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HAQ4362119.1"
                     /translation="MSNLWDYNQEAPIHYLIARHWDALKIEAVCRSLLAAVPKQQLEN
                     FLVADSLQREKVQAYFAAFKDQPLEYLHAQFHLFYQVAAPDDYNDLRGQLQLTFQADE
                     TAYTVLLGMARLGDQAKVEWRIFDI"
     gene            9011..9142
                     /locus_tag="IXR40_002310"
     CDS             9011..9142
                     /locus_tag="IXR40_002310"
                     /inference="COORDINATES: protein motif:HMM:NF012387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAQ4362120.1"
                     /translation="MLVTDAGEIRLRLFPDQAPLAVANWRSLAEQGVYDNTPFGSCH"
     gene            9111..9347
                     /locus_tag="IXR40_002311"
     CDS             9111..9347
                     /locus_tag="IXR40_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAQ4362121.1"
                     /translation="MTTHLSARVIKEFVIQGGALDGSGDEAVSSYEGFFADEVHRGLY
                     HFNGALALGDHGPHTNGNQFFIVQNTKAQADLLM"
     gene            complement(9425..10396)
                     /locus_tag="IXR40_002312"
     CDS             complement(9425..10396)
                     /locus_tag="IXR40_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HAQ4362122.1"
                     /translation="MEGTVLRIEQGSLHDGAGLRTVVYLKGCPLRCAWCSIPESQSKQ
                     IEKGFGQTMTAEEVMDEIEKDAVFYFHSDGGVTISGGEALVQADFAKEILQKSKYIGI
                     NTVLETSFCGAYNEIQKVAPYVDTLFVDVKMFTSKLHKQWTGLDNQQILKNIRRFLIE
                     YPNCEVRIRVPVVPGINMNLTELLTIACFVADLDRFVPLELLPYHCYGMHGYQALGLE
                     YPLADTPAPSPKEMFALADQLARTVPHLLVTALTKTFIYLLNPSFILWINERHSLAAA
                     SSRIELLLKSVSVFLRCFFEVNLSNEHWLNRYIFTVCRLSCDRCYDF"
BASE COUNT         3270 a         2551 c         2099 g         3069 t
ORIGIN      
        1 gttcaagcgc agtttattaa agggagattg gatgactcac cttcccattg tgaacactgt
       61 ggatcgattc gtattatccg caacggttcc tatacgacac gtactcagat gttgaaagtc
      121 aaagaaaagt tgactatttt agaattaaaa cgtacccgtt ttctatgcta tgattgtggg
      181 cagacctttt ctgcgaaaac ggacttagtt gatgaacatc atcaactaac aaaggaactg
      241 aaacaggcga ttctcataga actgtacgaa aatcaatcac gtaatctgaa aatcagaaga
      301 agtaccgtcg gctcaagcga tattggaaac tcttactcaa agattccacg acattggagc
      361 cgctcaaacg gcattatcat cgactgttta aacgaccaat tagtcaaaca gaaatcgtcg
      421 atgaaccgtt gtgcacaatg gtgtcctgaa cgtacagcga caccttccat atccagagca
      481 gtcgccacat cacggggatg gatgccatcc aaattaaaag caaccacgcc agtatgatgt
      541 tcaggatctt gcggtccgta aatggtgata ccgccgatcg cttgtaattt aggtaaaacg
      601 taggcaacca gttcttgctc ataacgatga atattctcca taccaatctc attcaagtaa
      661 tcgattgctc ctgcaatgtt cggagtacca gcttcaaatt tccatggcag ctctttccat
      721 gaactatcgt aaagattgac aaaatctatc atttcaccgc cgaattcgac tggctccatt
      781 tgttctaaca attgacgttt gccatataat acaccgattc ctgtcggccc gcacatttta
      841 tgcccgctaa aggcgaaaaa atctgcatcc aacgcttgta catcaactgt catatgcggt
      901 gctgcttggg caccgactgg actatcctca actacaacag cctgttcaac cctcagccgt
      961 ttcaagcaca acaaataacc ttctggatct ggtttgccga cctgaagatc atcgatcgtc
     1021 acaaaggaat caattttttc cttaatcatc ggatgtgctt caaaaaaata gtctagctcc
     1081 cgcagttcag aattgagact actccgattt tccagtgctg ctgatccgct gctcaaaatg
     1141 ttcagcatcc actggtctcc caaccgcttg acttatccct tcataaaagg acagttctgc
     1201 tgccgtccca acaccttgtt gatagtctgc aaaaggaatt ttatagccga actgctccag
     1261 taaataggct tcagtaaata gtgatgaata ctctcgtaaa acatccattc actgtcaatc
     1321 atcgtcccat caaaatcaaa aataagtgct ttggtcatct tctttccccc ttacccaaaa
     1381 caagcaaaag ctgtgtcctg ctctctctac agtatcagca taaaaactac cgtctgaaaa
     1441 gtcaaaggtg aaagaaatgt ggcgctataa tttctaggac tgatagtaaa tcattctatc
     1501 agtccttttg agcataaaaa aacaaaacat acagaagctc cgttagaatt gaatcaccac
     1561 aacacaatca aaggagcgtt ctgtatgcct gatcttcatc ttatcaaact attactagga
     1621 atcaaagatg gaaacattca aatcactcat gtcgagaaga aaaaaataca ttcaatcaac
     1681 agtatcgttg tttctgccac gctcattaaa acgattcagc cctgtcctca gtgtaaacag
     1741 gtgaatcaac atgggctgat cgttaagaac ggaaagaaaa aatcgctggt ccttctcaat
     1801 aagtgtgcga atcaacggac ttatcttgct ttggcaaagc aacggtacct ctgtcgtggc
     1861 tgtcacacct attttacggc gaatacctac attgttgaaa aaaactgttt tatcgccaaa
     1921 caagtacatt ataaaatatt ggaggaattg actgaaaaac aagcaatgac gacgatttct
     1981 aaacattgcg gcgtttcttg gtcaaccgtt tcgcgaacac tcgcttctct gctccccatg
     2041 acaaacgtga aaataaattg gttgcctcgc tgttcattgg tagatgaatt tcgttcattg
     2101 aaaaatcaag tcggtcccta ttctttttct tgtatagatg gcgatactgg gaaattactg
     2161 gatattcttc cttcacgtaa gaagaaagat ctcatttctt attttatgca atttgaacga
     2221 cgtgcacgtt taaacgtaaa aatactcgta acagatatga acgcctctta tgctttgctg
     2281 ataaaagagt gctttcctca tgccaaactc gttgtggatc gctttcacat cgtcaagcac
     2341 ctcattcgca gttttaagga tatttgacta tgagtcatga aaagcttcga ccgaaacgat
     2401 ccaatacaag ccaaacacta tcgacaagtg aaggctttat ctcgacttct gatcaaacga
     2461 caggacacgc ttgtttatga taaatggaca aaatggcgta attttggttg ggcctattta
     2521 accgaaagtg aagtcgtaga acgtctactt tctacttctg atgaactacg aatagcttat
     2581 gcttactatc aagaaattct tcaagctttt tatgacaaag aagcggacat cttctttcag
     2641 cttgtaaaaa caatgcccaa gtcggttcca agagaactgc atcatataaa aaaagcgttt
     2701 ataaactatg aatccggcat tcgtttagcc ttagagttgc cttactcaaa tggcaaaata
     2761 gaaaatctgc atacccacat caaagcattg aaacgaatag cttacgggtt aggatgagaa
     2821 ccagaatttt cttaatcaat catctgatca cttattaaac ataaaaaaac atctaaagca
     2881 gaaaatcaat tctaccttag atgttcttat atcactctat cagtcctatt tgacaaagag
     2941 ccagaaatgt ttgccgacta tacactagct ttgttgtgca aaatgctgag tatcaatttc
     3001 cacagggatt gctagaatat ctttcagctg aatgtataag gcatcgctaa ttttctcttc
     3061 ccgatcgttc aaccgatcca ctaaaatttc tttgccctcc agcgtttgaa aaacataccg
     3121 ttgaatgttg cctaaaataa atgattcctt ccatagaacc ggaatcttaa ccccctgagg
     3181 aaccggttca aattgaatca gctccggtct taaataataa atgcagcgat tgcccttagc
     3241 ggaaaactcg tgggtatact gattcagctc ataccattcg aaacgattat agttgccgat
     3301 aaattccgca acaaatcggc tctgaggatt ctgatacaat tccttcgagg tggaaacctg
     3361 agccacccgc ccagcttcca tcacaaaaat ccgatcactg attcgcatcg cctcttcttg
     3421 gtcatgagtc acaaaaatca tcgtcatccc tagcgattgc tggatagcgc gcaaatcccg
     3481 ctgcagctgt tttctaattc gggcatccaa agcacttaat ggctcatcca gcagcaggac
     3541 tttcggttca gtgaccaatg agcgagccag tgccacccgt tgtcgttgac cgccagaaag
     3601 aaactggaca tttttatctg cctgctccgt catatccacc aatgatagca tctcaaaaac
     3661 cttttcctga atcacctcag gactcagctt ctttaccttc aaaccaaagg ctacattttc
     3721 aaaaacagtc atagttggaa acaatgcata ctgttgaaaa acaaagccga tattgcgatc
     3781 cttcgtaggc ttatcggcaa tattctcatt gtccagcaca atctcaccgc tctttggttg
     3841 ttccaatccc gtgatacagc gcagcaacgt agactttccg cacccgctgg gacctagtaa
     3901 agtaaccagc tcaccctttt caatctgaat ttcatcaata gctaaaatct gtttttcatc
     3961 aaaaaacaga ttgagatcat gtatttctaa aaacattttc cgtcacaact cctttaaggg
     4021 cttctttttc gactgcttct cttccctcgt ctgcttaagg gacagctgtt gcttttgtcg
     4081 ataagtcagc ataaaggtag ttaaagcaat tcccaccata aacagcaaat acaaaaccat
     4141 cacagcgcta gccaaatggc cgttttcgtt catccgccgc agcatataga tgcgtaccgt
     4201 ctgaaatcga ccgccaatca acaggttcgt cagcatgtac tccccaaaaa ccgaagaaaa
     4261 aatcatcaga gaaactaggg tcacaccgat acggatgttt ggaaacagca cctggataat
     4321 aatcgtagac atcggggcgc ccaaggtttc tgctgcatcc actaattcct tcagattaat
     4381 taagcgcatc tggttgttaa gactaagata gacaatcggc aacgccgtaa taaacaatgc
     4441 acctaccaac actacaaaca ttgggatacc agtttcagca tacgttcgaa gcaaagccgt
     4501 taccaaaatc actcctggta aagcatacgg cagcaggagc agcttttcca gccaacgatt
     4561 caaacgaggg aaatacaaat gaatccaaat aatggtggga atcatcaaca acagaatcgt
     4621 caccaagacc acacctgcta ataaaagtga gcgacccacc gcagcaataa attccctgtc
     4681 cgtcagcagc tgttggaacc attgcaaggt aaaatcacta ggtaaaagcg attttgacca
     4741 tttagtggag ctggcataca aaatcgttcc aataatcggc agcaagtaat acaggacaaa
     4801 gcagaacaaa atcggtttta ttaacttttt cacgtctgca ccaccttgcc tttcttttga
     4861 ataatcaaca ttgccgttac cagcaggaca cctaaagcga ctgccaacgc actgcctaaa
     4921 ttaggcttgg cgaacacatc tcccgacact aaagccgcaa ttcgaatcgt taaaagattt
     4981 acattactgc tggtcagggc atacgctgtt tcataggtcc ccatgccatt agcaaataag
     5041 atgacaaagg tgctggcaat cgatggtcgc aaaaaaggca aagccacctt gaaccaagca
     5101 tacgctgatg aagcgcccag caattgtgcg gactccagcc attccttttt cacttccttc
     5161 atgctgggat acaaaaacaa gacccctaac ggaatttgga aataggtata cgtgatggtc
     5221 aatccccacc aagaatacaa attgaagtcc gctagaaatg gcaaaatcat tttcagcaca
     5281 cctacattcc ccaacaaaat aataaaagag aatgccagcg gaatcccagc aaaattagct
     5341 gccaaattgg aaacaaaggt gattttctcc tgcaatttag tcgatagatt cattaagcat
     5401 aaacataaaa taaacgtccc gattaaccca atcacactgg agctgacagc aatcagtacg
     5461 ctgttaacaa aggcctgtgt gtaatatttg ttgctgaaaa tatcactgta attggccaat
     5521 gtccactggt tagttaaatc actgtgcaag ctgcacagaa ccataaaaag cagcggcagc
     5581 agtaaaaatg cacagaagat aaaggaggca ggaaccagaa ccaagcgttt tttcatctct
     5641 ttcatcccct catcaattct tgaatgtcct gcattttctc tgacggtgca attcctaata
     5701 accagcaaaa caatggagcc gccagcagct gtggtacagt ttgttccttc agcttttggc
     5761 gtttatttga aatcaaataa aaaggaactt cacgatgtgc agccaagctg ccgccatgca
     5821 gtccgtgcgc atccatcccg tgatccgcag tcaccacgac ttgataacct ttttgcagcc
     5881 attcaggaag gtaaatagcc aataatctgt ccgcctgatt aaccgctgct gcatattcat
     5941 gagaatcggc ggtaaatttg tgaccgacat catcaatatt catcgaatgt acgaccaaaa
     6001 agtctggctg atactgattc actaaataat gggcatccgc aaataaatgc gaatcagggt
     6061 aagtgtcctc actataaaag atgccatgct gaatcagtcg ctcctcctga tgctggatgc
     6121 gatcaaccaa acgattatag ggggcttgat tgtacaactc gctgtaccag tggtaagcgg
     6181 cggctcctgt ttttccgcca gcttccttaa ctaattcaaa cagcgaccac tctttggatc
     6241 gctgagcatg gtaattacta tagatgccat tttcataggc tggaacgccg gtcatcagta
     6301 cttcgtataa cggacgtgaa ttgctgggca gctcactttt taccttcaat aagcttgctt
     6361 gctggtgctc aactaaatga ttcatgaacc caagctgggc gacggctgtg tcgtagcgac
     6421 agccgtctag tataactaca atcagtttgt caagtctact ttgcataggt cagtacctcc
     6481 gcctgccaaa gctctggaag ctctacagag gtcttgttcc aagcttcatt gtcttcaact
     6541 ggcaccgccg cttcataagc atcctccggc agtaattttt cagctacttc tttaggcagc
     6601 tctaccttgc gaataggtcg cgcatagccc tttgccaaat tgatttgccc ttcatcagat
     6661 aaaatatatt cccgtgctag ctttgccgca ttgggatgag gggcattttt attgattaag
     6721 gttgtatacc cgctaatgat ggagccgtct gttggcacag ttacctcaaa acgctcggag
     6781 tcaatttggt cacgataatt tagtccattg aagtcccaaa caactgccac atcgatttca
     6841 cctttttcaa gatttgctac gctggcatca acggtggaca aacggccttt ttctgccatt
     6901 tttttgtagt aattcagacc tggctgaata tccttttcgt cacctccgtt ggcaatcgcc
     6961 gcagccaata cagcaaattg tgcttggttg gcaatcgtca catcccccac gctaacttga
     7021 tagtcaccct cttgcagctc cttccagcta gtcggtgctt gcttcacatt ctctttatcg
     7081 gtgataaagg aaatggttcc cgtatagctt aacaaccaat ccccatcatc atcctttgcc
     7141 caatccggaa tttcctccca atagttggtc ttataaggta aggttaactc tttgctttca
     7201 gccaacggac cgaagctgat accgacatca ccaatatcgg cggttccatt ttttccttct
     7261 gattcaaact tagccaattc ttctgcactg gacatatccg tatccacgtg acttaagccg
     7321 tattcttttt caaggtcgtt ccaagtgcct acccaatttg cccaagtatc cggcattccc
     7381 aagctggcaa tctctccttc ttccttggct ttttctataa tcgtatctaa agagtcgtct
     7441 gccgcagccg attgcttcgt tgcttcacct gagccgcagc ctgtcagcag gatacttact
     7501 gttgctgcac aaaataaacc gatagtcatg ttacgaattt tttcattcat tttcattcat
     7561 tcttctcccc tttcgataat tccattctaa caaagctttg taatgagaga atcagtttct
     7621 tgaaaaggtt tcatgaacaa tgtaaaggtt gtatatggtt tgtaaatttc gacgaattcc
     7681 cgttaacctt ctaaagcttt tgcggtatga tagtagaaaa aaggaggctc cctatgcagt
     7741 attatgatca gcatctccac acgtattttt cctttgattc agaggaaaaa tttgaaaact
     7801 atttagccta tcagccggag tttttcgttt ctacggatca ctttgattta aacaatccat
     7861 ctaccggaaa agatgacatt ccggattatc cagcctatat aaacaaactg gactctttaa
     7921 aagaaaccta ttccaccaaa tttctgcgag gtatcgagat tggcgttgtt ccaggacaag
     7981 aagagcggat cgtggattac ctcgctcagc atccttatga tttaaagctg gtaagtattc
     8041 atcaaaatgg ccgctttgat tatatggacg atgtggtttt aaccaaagat cccattcaaa
     8101 ctaccaagga atattttgat cagatgttgc aggtcttgac ggattttcca gaaggagata
     8161 ttttgactca ctttgattat ggattacgcc gcttcacctt cacagcggaa gaattcgcgg
     8221 agcattttga ggctcagctg ctaacgattt tcaaaaaggt tgttgaacga gaattggcga
     8281 tggagttaaa tgccaagagc ttcttgaaat acggcaacga agacctttac cgttatgccg
     8341 ttcctttgta tcaaagtgtc ggcggaaagc tctttacctt aggctcggat gctcatgttg
     8401 ccgaagatta tcagctgggc tttaaaaaaa tgagtcagct gttggcagac tgtcaggtag
     8461 aaaagttgct agtcattcaa ggaaaagaac gccgcctgac gccgctgccg attttgtgat
     8521 tcctatataa tagaagaaag tggtgaaaaa aatgagcaac ctgtgggact acaatcaaga
     8581 ggcacccatc cattatttaa ttgcgcgaca ttgggatgcg ttgaaaattg aggcggtttg
     8641 ccgatccttg ttagcagccg ttccaaaaca acaactggaa aattttttgg tggctgacag
     8701 cttgcagcgg gaaaaagttc aggcttattt tgcagccttt aaagatcagc ctttggaata
     8761 tttgcatgcg cagtttcatc ttttttatca agtagccgcc ccagatgact acaacgattt
     8821 acgaggacag ctgcaattga cctttcaagc ggatgaaacc gcctataccg ttttattggg
     8881 aatggctcgc cttggtgatc aggcgaaggt cgagtggcgg attttcgata tttgatggca
     8941 ggatcaaggc gtttcagttg caaaccttcc tctctttcaa ttagaaaaac cgcagcagga
     9001 agaagtttgt gtgctggtca ccgatgctgg tgaaattcgt ctccgcttat ttcctgacca
     9061 agctcccctg gctgtagcca actggcgctc cctagctgag caaggcgttt atgacaacac
     9121 acctttcggc tcgtgtcatt aaggaatttg ttattcaagg tggcgctttg gatggttctg
     9181 gtgatgaagc tgtttccagc tatgagggct ttttcgctga tgaagtgcat cgcggacttt
     9241 atcattttaa tggcgccttg gccttagggg accacggccc ccacaccaac ggcaaccagt
     9301 tttttattgt gcaaaacaca aaggcgcagg ctgacctgct aatgtaaagc aagcatactt
     9361 ggagcttgga ggactaccgg agctggatgg tcgttatact gtttttggac aggtatacca
     9421 agggttagaa atcgtagcag cgatcgcagc tcagccgaca aacagtgaag atgtaccgat
     9481 tgagccagtg ttcattcgac aaattaactt cgaaaaaaca tcgtaaaaag acactcactg
     9541 acttcagcaa aagctctatt cttgagctgg ctgcagctag tgagtgtctt tcatttatcc
     9601 ataagataaa gcttggattc aataaataaa taaatgtttt ggttaaagct gtgaccagca
     9661 aatgaggaac cgtgcgagcc agttgatctg ccaatgcaaa catttcttta ggtgaaggcg
     9721 ctggcgtgtc tgccaacgga tactccagtc ccaatgcttg gtaaccgtgc ataccatagc
     9781 agtggtacgg tagtaattct aacggtacga accgatcaag atctgccaca aaacaagcaa
     9841 tcgtcagcag ctcggtcagg ttcatattga tacctggaac cacaggaact cgaattcgca
     9901 cttcgcagtt aggatactca attaaaaagc gacgaatatt cttcaaaatt tgttggttat
     9961 ctaagccggt ccattgtttg tggagcttgc tggtaaacat ttttacatcc acaaacaatg
    10021 tatccacata gggagctacc ttttggattt cattataagc accacaaaag ctggtttcca
    10081 gtacggtatt gattccaatg tatttcgatt tttgcaaaat ttctttagca aaatccgcct
    10141 gaaccagtgc ctcgcctccg ctaatggtca ctccgccatc cgagtgaaag taaaaaacag
    10201 catccttctc aatctcatcc attacctctt cagcggtcat ggtctggcca aatccttttt
    10261 caatctgctt gctttgtgat tcgggaatcg aacaccaggc acagcgtaat gggcagccct
    10321 ttaaataaac aacggtccgt aaaccagcac catcatgtag agaaccctgt tctattctta
    10381 atactgttcc ttccatatag atttttgaat tacacactag tttaaactaa aacacacaag
    10441 gaaaaactta ccatttaatc ataaaattag ctcatataaa tatactagga tgtaaaatag
    10501 actggtcaaa atctggtcaa aaaagaggac taatacaggt agtcctcttt tttgttattt
    10561 taatattcta aatcattttt tattggttta ttcccttatt cgatgtagac tcaaatcact
    10621 atatcactag atatcaaacg gcgtcatacg gaatcaaaaa catcaaattt gacctgttaa
    10681 atggtcattg aataacattc aaaatcaata aaacggagtc agacacggag tcaaaaacgc
    10741 tgagagtaaa aaatatatac agccttgtag gtaaagtacc acagggctgt atatttttta
    10801 tttcagatta ccttaaatga ttccatttac tttttatctc attttttcct actagttagt
    10861 atcaaatact ctcctatttt ctcaataaac tatttttgga tacatggtat ctgaaacagc
    10921 taaaaccttg tcattacagc aaaaaatcac gttatccaga ctgtagacaa agtccatttt
    10981 atggatgat
//
LOCUS       DACGEU010000090        10639 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.091, whole genome shotgun sequence.
ACCESSION   DACGEU010000090 DACGEU010000000
VERSION     DACGEU010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10639)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10639)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10639
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.091"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(926..1165)
                     /locus_tag="IXR40_002313"
     CDS             complement(926..1165)
                     /locus_tag="IXR40_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004609551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4362123.1"
                     /translation="MKKEYGYPTLKVICQASAGNETAIREILKFYDAYICKLCLRPFY
                     HSESGKIIMQVDEELKGQIHTEMMKAILKFEIRVK"
     gene            complement(1170..1610)
                     /locus_tag="IXR40_002314"
     CDS             complement(1170..1610)
                     /locus_tag="IXR40_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004610571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAQ4362124.1"
                     /translation="MRKGGEIMNPSSFEHIVRIQFNALMMTVIKCTVKNRNRQFARRS
                     KREVLFCELSDTKNVECVTKDNYSCDYISFEVLNFTIQISNEKLAVALYKLSNKERDV
                     ILLRYFQSMSDQEIAELYHVSRSAIYRRRSNGLKKLKTVLKERN"
     gene            complement(1781..2722)
                     /locus_tag="IXR40_002315"
                     /pseudo
     CDS             complement(1781..2722)
                     /locus_tag="IXR40_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008728838.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
     gene            complement(3423..4472)
                     /gene="cfr"
                     /locus_tag="IXR40_002316"
     CDS             complement(3423..4472)
                     /gene="cfr"
                     /locus_tag="IXR40_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cfr family 23S rRNA
                     (adenine(2503)-C(8))-methyltransferase"
                     /protein_id="HAQ4362125.1"
                     /translation="MQQKNKYIRIQEFLKQNKFPNYRMKQITNAIFPGRINNFNEITV
                     LPKSLRDMLIEEFGESILNIVPLKAQQSTQVSKVLFGISGDEKIETVNMKYKAGWESF
                     CISSQCGCNFGCKFCATGDIGLKRNLTSDEITDQILYFHLQGHSIDSISFMGMGEALA
                     NVQVFDALNVLTDPALFALSPRRLSISTIGIIPNIKKLTQNYPQVNLTFSLHSPFNEQ
                     RSELMPINERYPLSDVMDTLDEHIRVTSKKVYIAYIMLHGVNDSIEHAKEVVNLLRGR
                     YRSGNLYHVNIIRYNPTVSSRMRFEEANEKCLVNFYKELKSAGIKVTIRSQFGIDIDA
                     ACGQLYGNYQKTNSQ"
     gene            complement(5100..5660)
                     /locus_tag="IXR40_002317"
     CDS             complement(5100..5660)
                     /locus_tag="IXR40_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008728836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAQ4362126.1"
                     /translation="MRISKEPEERKQEILETAIKLFSVNGFEKTSISDIAKEIGIAQG
                     LCYRYFPSKDVLFQSAINEYSNILVANMTKNINIKKDSLKDILRKMILFAEQEDDTYY
                     PVFHNNQNKNFHNLLTLNVCEKLFPIVSEIIERANYTNEIQVNDVEMYASFCIYGQLG
                     IILNTDISIKEKSSRIKAFFRDLFRL"
     gene            complement(5684..6295)
                     /locus_tag="IXR40_002318"
     CDS             complement(5684..6295)
                     /locus_tag="IXR40_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008728833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAQ4362127.1"
                     /translation="MNITKQKSQKTFDKQAADYDTNIQGEHARKLYKPIIENLKNKNI
                     HSILDLGCGTGALLKEIKELNIAEQLFGIDISPNMLEIAKNKLGNDATLILGDSERLP
                     FEDSSFDAIVCNDSFHHYPQPDIVEKEVSRCLKQNGVFIIGDCWQPIGARQIMNYYMK
                     HSNSGDVKIYSKKEMLLLLSKDFHEIEWKSFGTRSCLIIAYNN"
     gene            complement(6646..7281)
                     /locus_tag="IXR40_002319"
     CDS             complement(6646..7281)
                     /locus_tag="IXR40_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4362128.1"
                     /translation="MEHYEKKISFLGENIQTIRKHRGMKQQELADKIGINMQSLSKIE
                     RGVNFPTFDTLEKIMDVLGVMPNELLSGEWKYVNQSEKEVCQFLRIEERLNAELKHGH
                     YDNFFDSEEEWLEYELEKLREYITDYINGKSIVASDLYPIKEFIQHLKFQKLLDRYDD
                     LYSMDMFGESIEGHKYRTPYQVVKMINPNSKEDMELLREVLKNNHFDDEDE"
     gene            7667..8830
                     /locus_tag="IXR40_002320"
     CDS             7667..8830
                     /locus_tag="IXR40_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008816501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HAQ4362129.1"
                     /translation="MINKGKNTIFTPQKKRGIRKEQCTITTHKNLSVKIDYISIVFET
                     ATAEDVIMHILDLPTDIFNVYPAMIKFKTYQARWQIGDIYVSGDARKTEDNPQGLGCY
                     LVMTGRGCDDIFRILDSRNYTFGDMFRRCERRYGLDNFHFTRLDIAIDDKNEKPFFTI
                     EQIKKKCEKEEFISNSEGYHFDESKFDDFDTAKTVYIGAGKSGLSYRFYDKDKEVCSK
                     HNKTLDEVGSWKRTEMQLRDDKAHVFAMTFKDRPLELGELAFGLLANNLRFVVPNRNE
                     SNKSRWKTCRFWERFLGAVEVLKLQVPKLHNSLEETQQWLTEGGVISAVKSFYFLEEH
                     DALGGLEKVGTMLDRARYSSSLSSKLTAHLQRIDRTDLIPYIQYDTKHGKGGI"
     gene            8830..9033
                     /locus_tag="IXR40_002321"
     CDS             8830..9033
                     /locus_tag="IXR40_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002607397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HAQ4362130.1"
                     /translation="MNNNDIPVWEKYTLTIEEASKYFRIGENKLRRLAEENKDAGWLI
                     MNGNRIQIKRRQFEKVIDKLDAI"
     gene            9112..10305
                     /locus_tag="IXR40_002322"
     CDS             9112..10305
                     /locus_tag="IXR40_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAQ4362131.1"
                     /translation="MKEKRRDSKGRILHTGESQRTDGKYLYKYVDAFGNTKYVYAWRL
                     TPTDPTPKGKREKPSLRELEQQIRRDIEDGIDSTGKKMTLCQLYAKQNLQRANVKKST
                     QKQREQLMRLLKEDKLGARSIDTIKPSDVKEWALRMKDKGFSYNTINNHKRSLKASFY
                     IAIQDDCVRKNPFDFKLSEVLENDTKEKVALTEEQEQALLSFIKTDNVYHKHYDDVLI
                     LLKTGLRISELCGLTVADIDFKNEVVIIDHQLLKSKEQGYYIETPKTKSGIRQVPLSR
                     ETIQAFQRVMKKRPKAEPFVIDGRSNFLFVNQKGKPKVAIDYNALFIRMVKKYNKHHK
                     DNPLPHITPHTLRHTFCTRLASKNMNPKDLQYIMGHSNISITMNWYAHASIDTAKSEV
                     QRLIA"
     gene            complement(10312..10473)
                     /locus_tag="IXR40_002323"
                     /pseudo
     CDS             complement(10312..10473)
                     /locus_tag="IXR40_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008788611.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin-binding domain-containing protein"
BASE COUNT         3540 a         1899 c         1677 g         3523 t
ORIGIN      
        1 taaaatattt ttattaatat tttataactt tacgcaagat cataattttg tcgtgtagat
       61 atttcattat atcactaaag ataataagat ttaatgacct cattaatatt gtttgctagg
      121 tccaaactct tattaaactt tctttgctat aaaacccaaa catagtaata aaagaataac
      181 ttattacctt taaattatac taccaacaaa tggtagtata ttattaattt atataatatg
      241 aaacctaaaa tatagtagta tgttaattta tactaaatta aataaagtac tacctttaat
      301 aggtagtact ttattatcaa gccattattc cttcttctac tagttctttt tgtcacataa
      361 ttttgcaatc aataaatgtt gcgcaataag tataagaatt ccattttcta aatttgaaag
      421 gtgatccata atttcatgtt caagtagttt attaattgtc cacttgtcgc ttcatctaaa
      481 aattttatag gttttaggaa tgctattcgc ttattttagg aagattttaa ctgtttgctg
      541 tagatatata tcatactagt atcgtaataa aagtactcta aaagaagaat tttcaaatac
      601 gcaaaattaa gtacgaaaga gttgaaacaa atttggagaa aaatgagcat agaatgtcta
      661 atgagttaaa tagacctaaa aattatctaa aagtggagca aaattaggaa ttacaaacaa
      721 aacactaaat tagttaaatt aaattttata tctgattttt gattatccgc ataaacacta
      781 tactttcaaa cattttgaag tatagaaaac tattcatttt accacgaatt taccacgatt
      841 gaatgagcct tgatatgaca caaaaacaac atgggagata gcacaaatat ctgtgtatct
      901 cccgtttttc attcatgtag tatgattatt ttactctgat ttcaaatttc aagattgctt
      961 tcatcatttc tgtatggatt tgacctttta attcttcatc aacctgcata atgattttac
     1021 cactttcaga gtggtaaaac ggacgcaagc ataatttaca tatataagcg tcataaaact
     1081 tcaaaatctc tcttatggca gtttcatttc cagcagacgc ttgacatatt acttttaatg
     1141 tagggtagcc atattctttt ttcattggtt caattccttt ctttcaatac tgtttttagt
     1201 ttcttcaatc cgttacttct tctgcgataa atagcagaac gtgatacatg atataattcg
     1261 gctatttctt ggtcgctcat actttgaaaa tagcgtaata gaattacatc acgctcttta
     1321 ttcgataact tatataaagc aacagcaagt ttctcatttg atatttgaat tgtaaaattc
     1381 aagacttcaa acgaaatgta atcacaagaa tagttatcct tagttacaca ttcaacattt
     1441 ttcgtatctg ataattcaca gaataaaact tcacgcttag aacgtcttgc aaactgtctg
     1501 tttctgtttt ttactgtgca tttaataaca gtcatcatca aagcattaaa ctgtattcta
     1561 acgatatgct cgaaagaaga tgggttcata atctcacctc ctttccgcat acgctgaaat
     1621 atataaacgg agataccgtc tatatctttg gaaaatacaa aaagaagaac aagaaaaaag
     1681 tccgtacaaa atataccgtc tgtacgaact tttaatattg taaaatattt agttgttgat
     1741 aaaatgctgt taggtagtgc ataatcgtat aagattattc ctaaaacttt ccacagcagt
     1801 tactttcaat gcttttatat cttgcttttt tagtcctatc ataaagtttt ccatataacc
     1861 gcttaataat ttgattactt gttaaaatag ttataatgca ggcgactatg tgactgatta
     1921 aaatcgctat ccaaacacca tttaaatttt ctgccagcca agataataga taggcaaaag
     1981 gaatacgaat aataatatag tagaatatca ttagtatcat actttttgtt ggttttccta
     2041 taccatttaa agtacctaag tagcaactag taatagtgta aagaacataa ccgatactaa
     2101 caattaaaaa ataatggctg acaacatttg ttacagctac gttggaaaca aacaattttg
     2161 ccaactgttt agagaagaaa ataacaactg ctgataatac acttgaaaca acaataccat
     2221 attttaacgc caatttcaga taattctttg ctctgtcgat acgttgtgct ccaatacatt
     2281 gccctacgat tgaagtcaac accatattaa gagccatagc aggataaaat aatatcattt
     2341 ctaattttcc agcaactccg tagccagcaa tagcagaaat actataagta ctaacaatag
     2401 cagttaaaaa tgttgtacta atagcaggaa tactttgttg aatgacagac ggcacagcat
     2461 tttttacaaa cggcataatc tcttttgtat caaaatcaga tagtgaaagg ttaaataatt
     2521 ttttacgata aatataaatg cacataaacg ccaaacaaat aatctgtgat attaaggttg
     2581 cgattgccgc tccgtgaaat ccaattatgt taatgaaaat aggatctaaa atagcattca
     2641 ataaagtaga cacaagcatt gcaactgctt gaaacatagt attgccaaaa cttcttaaaa
     2701 tggctgtaaa gtataaatac aaaatagttt atggattagt gaatcattat tataggttca
     2761 gtcctttcaa ttttgttcat taaaatatgc tctaaggcct tttagataag cgaaattata
     2821 aatatttcaa ttgacgttgc ctttttaaat tgagaacaaa tgtttcccat ttcttttctt
     2881 gcttttcata tcaaggataa cacgattgta ttccttttgc atatccacct tattttaagt
     2941 gatttttggt attcgtgttc atctcttcat tggatacact actgtcttcc acctgattat
     3001 caataattca ctgcatccgc aattctcgca tgacaaattt ttccaactac tgtttagagt
     3061 aatcttctga tacatcaatt tcaaactctt caaataatta ttgcatataa tttccatgtt
     3121 ggacggtagt tgaatttcat tattgtcagt caacgtccaa aaatccgtaa tgactacatg
     3181 atctctactg atactttgac tgaaattatt tttttgttta acactaatca tcaccatttt
     3241 tcacattcaa taatttaatt gcagtttcaa tttttacaaa cgacttttta gctccacttg
     3301 agtgatgcct atttttcttt ctaagattcc ttttatcata aatatcctaa taagtttatt
     3361 tatcgttact aaataaatta ttagggtact tcccacgttc taaacatcac tctcacctca
     3421 agttactggc tattggtttt ttgatagttt ccatacaatt gaccgcaagc agcgtctata
     3481 tcaatgccaa attgacttct aatggtaact ttaattcctg ctgactttaa ttctttataa
     3541 aagttgacaa gacatttctc atttgcttct tcaaaccgca tccgtgaact aacagtcggg
     3601 ttatatctaa tgatgttcac atgatacaag ttcccactcc tatatctacc tcttaaaagg
     3661 tttacgactt ctttcgcatg ttcaatagaa tcattaactc cgtgcaacat aatataagca
     3721 atataaactt tttttgaggt tactcgtata tgctcatcta atgtatccat cacatctgat
     3781 aatgggtagc gttcattaat tggcattaac tcacttcgct gttcattaaa aggagaatgt
     3841 aatgaaaatg tcaggttgac ctgcggatag ttttgagtca attttttaat gtttggaata
     3901 attcctatag tggatataga taacctacgc ggacttaaag caaacaacgc aggatctgta
     3961 agtacattta aagcatcaaa aacttgtaca ttcgctaatg cttctcccat tcccataaaa
     4021 gaaatactgt caattgaatg cccttgtaag tgaaagtaca aaatctggtc agtaatttca
     4081 tctgaagtta agttacgttt taaacctata tctccagttg cacaaaattt acaaccaaaa
     4141 ttacaaccgc actgcgatga tatacaaaat gactcccaac cagctttata tttcatattt
     4201 accgtttcta ttttttcgtc tcctgaaatt ccaaataaga cttttgaaac ttgtgtagat
     4261 tgttgtgctt ttaaaggaac aatatttaaa atcgattctc caaactcctc aattaacata
     4321 tctcttagtg atttaggaag aaccgttatt tcgttgaaat tatttattct ccctgggaat
     4381 atagcatttg taatttgttt cattctataa ttaggaaatt tattctgctt caagaactct
     4441 tgaattctta tatacttatt tttttgttgc atgttttctc atccttccat ataactctgg
     4501 tttgtttgcc gtagaggaaa agctccgata actgtttttg tatggttata tggcttaaaa
     4561 aaggacagac tactcccttt gtatgccgaa cgattaccaa cttttgcatt tttaccaaac
     4621 aaaattctaa aaacagttaa cattgctttc acctctttct tgtcaatata agtgttaaat
     4681 agtataccat aaatctttcc ctatgtaaac tcaaaaaaat acatgtaatt tgaaaaacaa
     4741 acaattttgg atataaatgt agttaaacta acctgcaccg tttaccgtta acatttaagt
     4801 taaaccattc acaattttgt tcttatttca acataaatat ccagttttct ttaaagtaag
     4861 ttattcaatt aaagggcgtt tgttaaagta gaaaaattgc tgaatcaatt ttaaatccat
     4921 ttcaacatac acaaattccg cacaataatc caaataccca ttaatttttt caaaatcctc
     4981 aacaatcatt atctcctgtg gctattaggt agaggggttt cctctctgac tatattgcag
     5041 gaggtaattc gtatggacga attataataa atattccctg ccttttggca ggggaagatt
     5101 taaagcctaa acaagtccct aaaaaatgcc tttatccgtg aactcttttc tttaattgat
     5161 atatcggtat ttaaaataat tcctagttgt ccatatatgc aaaaactggc atacatttca
     5221 acatcattga cttgtatttc atttgtgtaa tttgctcttt caataatttc agatacaata
     5281 ggaaaaagtt tttcacatac attcaatgtt aataaattat ggaaattttt attttggtta
     5341 ttatgaaaaa ctggataata tgtatcatct tcttgttctg caaaaagtat catcttccgc
     5401 aaaatatctt ttaaactatc cttttttata tttatatttt ttgtcatatt ggcgactaaa
     5461 atatttgaat attcattgat agcagactga aaaagtacat cttttgatgg gaaatatcta
     5521 taacataatc cttgtgctat tccaatttct tttgctatgt ctgatattga agttttttca
     5581 aacccattta cactaaataa tttaatggct gtttctaaaa tttcttgttt acgttcctct
     5641 ggttcttttg aaatacgcat tgttttcttt cctttcttgc ggtttaatta ttgtatgcta
     5701 taattaaaca agatcttgtg ccaaaagatt tccattcaat ttcgtggaag tcttttgata
     5761 ataataacaa catttccttt tttgaataaa tctttacatc tccactattg ctgtgtttca
     5821 tatagtaatt cattatctgt cttgctccga ttggttgcca acaatcaccg ataatgaaaa
     5881 ctccattttg ctttaaacac ctagacactt ctttctctac aatatctggt tgtggataat
     5941 gatgaaatga gtcattacat acaatggcgt caaaagaact atcttcaaaa ggtaatctct
     6001 cagagtcgcc taagataagt gttgcatcat ttcctagttt attttttgca atttcaagca
     6061 tattgggaga tatatctatt ccaaatagtt gttctgctat atttaattct tttatttctt
     6121 taagtaacgc acccgttcca caacctaaat ctaatataga atgtatattc ttatttttta
     6181 aattttctat aatcggctta tagagttttc gagcatgttc cccctgaata tttgtatcat
     6241 aatcggcagc ttgcttatca aaagtctttt gtgatttttg tttcgtaata ttcatgtaat
     6301 caactccttt cactaaaatt atatctcgtg aatgaacgat tgtcaatgaa taaaattcat
     6361 tgaatttcat tcatttcaaa gacgtgtatc tctgatttaa aatacacgcc tttttgatta
     6421 ccctacaatc ttccagttac tattccttat atagcccaaa tttgtaccgt gacaatttca
     6481 ttgatattat ccgatttacc acaaatcaaa ttttatcttt tcttcctctt gattaccctc
     6541 cacagaaaag aaaaagccct gtcaagagcc ttgccaccat tggtggtgct ttgcactctt
     6601 tactgggctt tttgtttgct gtatcttcta caaagaggga aaaagttatt cgtcctcatc
     6661 atcaaaatgg ttatttttca atacttcccg taataattcc atatcttctt ttgaattggg
     6721 gtttatcatt tttacgactt gataaggtgt cctatattta tgtccctcta tgctttcccc
     6781 gaacatatcc atgctgtata aatcatcata gcggtctaac agtttttgaa acttcaaatg
     6841 ctggataaat tctttgattg gataaaggtc ggacgctaca atacttttcc cgttgatgta
     6901 gtcggtaata tattcccgta acttttccaa ctcatattcc agccattctt cctcgctgtc
     6961 aaagaagttg tcataatgtc catgttttag ttctgcattt aatcgttctt caattcttaa
     7021 aaactggcag acttcctttt cggattgatt aacatacttc cattctcccg ataataattc
     7081 attgggcatt acacccagca cgtccattat cttttctaat gtatcgaagg taggaaaatt
     7141 cacacctcgt tcaatcttgg aaaggctctg catattgata ccgattttat ccgcaagttc
     7201 ctgttgtttc attcctctgt gttttcttat ggtctgtatg ttctctccta agaaactgat
     7261 tttcttttcg taatgctcca taacttagta taaccgctcc tttcgttgct tttcttggta
     7321 tttataagca tatcatactt aatctacatc taaaagtcaa caaaaacttc ttgacaagta
     7381 attctaatgg cgttattatc gtatcagata gagtgattaa gcacgataag gtcaatcaca
     7441 cgcttgagta agcatagaga agatacattt tcactttgat agcatgaata agcatggact
     7501 atcagaccga aaatagtggt ttccaaaagg ggctggctgg acggggcacg tcccccagac
     7561 gtgttcggac agacagttcc ttttggaaaa ggaacgccta aaggcgttcg cagagggcgt
     7621 atatgtaaca ccgccctgcg tatacatgtc atagtaccta gaaactgtga taaataaagg
     7681 aaaaaacacg atttttaccc cgcaaaaaaa acggggcata cgaaaggagc aatgcactat
     7741 aactacacac aaaaatttat ccgttaagat tgattacatc agcattgtat ttgaaacggc
     7801 aaccgctgaa gatgtaatca tgcacatttt agatttaccg actgacattt tcaatgttta
     7861 tccagcaatg ataaaattca agacttatca agcacgctgg cagattggag atatttatgt
     7921 atcgggggac gcaagaaaga cagaggataa cccacagggg ctaggctgtt atcttgttat
     7981 gactggcaga ggttgtgatg atattttccg tattctcgac agtaggaatt atacctttgg
     8041 ggatatgttt cgacgctgtg agcgaagata cggactggat aactttcatt tcacaagact
     8101 tgatattgcc attgatgata agaacgaaaa gccattcttt accatagagc agataaagaa
     8161 gaaatgcgaa aaagaggaat ttatttctaa tagtgagggc taccactttg acgaaagcaa
     8221 gtttgatgat ttcgacaccg caaagactgt ttatatcggt gctggtaaat cgggattatc
     8281 ctaccgcttt tatgataagg ataaggaagt ctgttcaaaa cataataaga cacttgatga
     8341 agtcggcagt tggaaacgga cagaaatgca actgcgtgat gataaggctc atgtttttgc
     8401 catgacattc aaagacagac cgctggaact tggggaactg gctttcgggc tattagcaaa
     8461 caacctacgc tttgtcgtgc caaacagaaa tgaaagtaat aagagcagat ggaaaacgtg
     8521 tcggttttgg gaacgatttt taggggctgt ggaagtcttg aaactgcaag taccgaaact
     8581 acataattcc cttgaggaaa cacagcaatg gctcacagag ggtggcgtga tttctgctgt
     8641 caaaagtttt tatttcttag aagaacatga tgcattaggt ggactggaaa aagtgggaac
     8701 tatgcttgac agggcaagat acagcagttc cctttccagt aaattaaccg cccacttaca
     8761 gaggatagac cgcaccgacc ttatccccta tatccagtat gacacgaaac atgggaaagg
     8821 gggtatctga tgaataacaa cgatattccc gtatgggaaa aatacaccct taccattgaa
     8881 gaagcgtcaa agtatttccg tatcggagaa aacaagttaa gacgcttggc agaggaaaac
     8941 aaggacgctg gctggctcat tatgaatggc aaccgcatac agattaaacg ccgacagttt
     9001 gaaaaggtca ttgataaatt ggacgcaatc taatgcaaat gagccttgta tgtgttatga
     9061 tgaatacaag tcatatcaag gctctttcca acaaggaaag gagcagacac catgaaagaa
     9121 aaaagacggg atagtaaagg acgtatcctg catactggag agagccaacg aacagacgga
     9181 aaatacttat ataaatatgt ggacgcattt ggaaacacaa aatatgtgta cgcttggaga
     9241 ttgacaccca cagacccgac accaaaggga aaacgagaaa aaccctcact tcgtgaactg
     9301 gaacagcaga taagacggga tattgaggac ggtatcgaca gcacaggcaa gaaaatgacg
     9361 ctttgccaac tctatgccaa acagaactta cagagggcaa atgtgaagaa aagcacacaa
     9421 aaacaacggg aacaactcat gcggttattg aaagaggata agttaggtgc taggagcatt
     9481 gatacgataa aaccctctga cgttaaagaa tgggcgttac gcatgaaaga caaaggcttt
     9541 tcctacaata ccattaacaa ccataaacgc tcgttaaaag cgtcattcta tattgctata
     9601 caagacgatt gcgtaaggaa aaatcccttt gatttcaagt taagtgaagt tctagaaaat
     9661 gataccaaag agaaagtcgc attgacagag gaacaggaac aagccttatt gtcatttatc
     9721 aagacggaca atgtgtatca taagcattat gatgatgtgc tgatattatt aaaaacagga
     9781 cttcgtatct cggaactgtg cggactgaca gtagccgata ttgatttcaa gaatgaagtt
     9841 gtgattatcg accaccagtt attaaagagt aaggaacaag gctattatat tgaaacgcct
     9901 aaaacaaaaa gcggaataag gcaagtgcca ttaagcagag aaacgataca ggcatttcaa
     9961 agggttatga agaaacgccc aaaggcagaa ccatttgtga tagacggacg gagcaatttt
    10021 ctgtttgtca atcagaaagg caagccgaaa gttgccattg attacaacgc cttatttatc
    10081 cgtatggtaa agaaatacaa caagcaccac aaggacaatc ccttgccaca tatcacaccg
    10141 catacgctac gccatacgtt ctgcacaaga ctggcaagca agaacatgaa cccaaaagat
    10201 ttacaatata tcatggggca ttcaaacatc agtatcacaa tgaactggta cgctcatgcg
    10261 tccatagata ctgcaaaatc agaggttcag cgtttaatcg catagaagta tttaccacga
    10321 ttttaaccac gcttgatagc gaaaatataa aaagatagac ctagatatgt gaggtttacc
    10381 acaaaagcaa aatgcccgta gagccgataa aataaggctt tgcggacatt taagaagata
    10441 taaaaagata gttaaaaaga tatatataat tttatataat tttccgtaat atttaatata
    10501 tatgaaaagg aaaacgtaga aaattacgtc tacgttttcc tatttagttc ttatttttat
    10561 taaattttat atttgctctt ttcacttttc ggaataaatt cactgtgact cttgatacct
    10621 tcttttatat attgctaat
//
LOCUS       DACGEU010000091        10551 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.092, whole genome shotgun sequence.
ACCESSION   DACGEU010000091 DACGEU010000000
VERSION     DACGEU010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10551)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10551)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10551
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.092"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            412..660
                     /locus_tag="IXR40_002324"
                     /pseudo
     CDS             412..660
                     /locus_tag="IXR40_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877177.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
     gene            782..1108
                     /locus_tag="IXR40_002325"
     CDS             782..1108
                     /locus_tag="IXR40_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HAQ4362132.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLQLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEF"
     gene            1176..1889
                     /locus_tag="IXR40_002326"
     CDS             1176..1889
                     /locus_tag="IXR40_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HAQ4362133.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYLVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PIFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEEKEIVTLITCGDMDAVTRLVVQGELESVTP
                     IKDATDDMRSAFNLETKTF"
     gene            2199..3051
                     /locus_tag="IXR40_002327"
                     /pseudo
     CDS             2199..3051
                     /locus_tag="IXR40_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
     gene            3172..5037
                     /locus_tag="IXR40_002328"
     CDS             3172..5037
                     /locus_tag="IXR40_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4362134.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            5085..6494
                     /locus_tag="IXR40_002329"
     CDS             5085..6494
                     /locus_tag="IXR40_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HAQ4362135.1"
                     /translation="MEQLLPNQLEGAYDRDGKGLSVADAMPGGKQRFAIIGSEEFDWT
                     IDQEKYIYPNHRGIDHYDRFKEDLALFAEMGFKCYRFSIAWTRIFPNGDEGTPNEAGL
                     EFYDQLIDECLKYDIEPVITISHYEMPLHLAKEYGGWKNRKLIDFYERFAQTVLERYS
                     SKVKYWMTFNEINSAFHFPALSQGLVKSNGAGEYQNIFQAWHNQFVASSKAVKIGHEL
                     RSDIQIGCMIIYATTYSIDANPVNQAATMIQNQEFNFFCTDVQVRGEYPAYTARTHKK
                     YGVDPEKLEQTEKDFQLLKEYPVDYIGFSYYMSTAINETDPQAATSEGNLLGGVKNPF
                     LEASEWGWQIDPEGLRIALNELYNRYQKPLFIVENGLGAIDHMEEDGTIIDDYRIDYL
                     RRHIEAMANAVADGVDLMGYTPWGCIDLVSASTGEMSKRYGFIYVDLDDEGNGTLNRS
                     KKKSFDWYKEVIASNGVNL"
     gene            6602..7303
                     /locus_tag="IXR40_002330"
     CDS             6602..7303
                     /locus_tag="IXR40_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAQ4362136.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            7462..7941
                     /locus_tag="IXR40_002331"
                     /pseudo
     CDS             7462..7941
                     /locus_tag="IXR40_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015510350.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            8789..9364
                     /locus_tag="IXR40_002332"
     CDS             8789..9364
                     /locus_tag="IXR40_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HAQ4362137.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            9364..9804
                     /locus_tag="IXR40_002333"
     CDS             9364..9804
                     /locus_tag="IXR40_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HAQ4362138.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            9820..10521
                     /locus_tag="IXR40_002334"
     CDS             9820..10521
                     /locus_tag="IXR40_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HAQ4362139.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
BASE COUNT         3572 a         1713 c         2311 g         2955 t
ORIGIN      
        1 atgttggatg tttacgaaaa tgcagaacta aaaatcgaat tttcaaaaca gaatcactat
       61 ttttttgtag aaatgtatct ggcatctaga aagagcaaat cagcctactg acttactgtc
      121 aaaggataag cttgaggaaa gtctacacgg agatagagac aacaacacag catattcaaa
      181 agaaacagaa gcgtgatgac cgttgtcacc cttctgtttc ttttgctatg tagttaaaca
      241 aagtagttga cacttccgct acttagtatt agtacgaaag tatacttcat gatactaagt
      301 agataagaag tgaaaagcgg aacccacgat cgtcaaaatg ctaactgctt tgcttacacc
      361 agataaaggg aagagcaata tcgcttattt taggcgtgga gaagcaagaa aatccctacg
      421 atcacacaaa aaatgctgac ccagcagtta agagagttag aacaagatgg cattgtccat
      481 cgaaaagtct ataaccaagt cccgcctaaa gtagagtact cgctcaccga agaaggaaaa
      541 tcattaagag agattctagt agcgatgtct gtttggggag aagaacgtat cgaaaaacaa
      601 aaagcctcag gggaagaagt cacattactg catacacatg gtggctacct aaattactga
      661 tttctatgac atttatttta aataaaagaa aacaggagtt tttttaaaag catcatctat
      721 tttttatgta aaaaaatggt atgattaatc aagtaagaaa tgattggaag aaggcaagca
      781 aatgaatagc atggaaaaag ttaaccagtt tagagatgaa cgtaattggc gacaatttca
      841 taacgaaaaa gatttggcta tttctatttc tttggaagca tctgaattgt tagaactttt
      901 tcaatggaaa acgccggaag aagtaaaaga aacacaatta gaacgaatca aagaagaact
      961 ggcggatgta ttgatctatt catacatgat ggcagacaac cttcagctgg atctagatga
     1021 gatcattgaa gaaaaattga tcaaaaataa tttgaaatat cctgtagaaa aaagcgcagg
     1081 tgtacgaaaa aaatacacag agttttagaa atgtgtcatt cggctgttgg aaagagcaaa
     1141 agaaaaacag taaaatgagt ctggagggag agaaaatgaa aaaaaaagga aaagcaaaaa
     1201 gatggctagt caatatcctc ttgttcctct tgttattagt aggactagct ttgattttca
     1261 atgaacagat caaggattat cttgtcagag agacaggaga taaatatgct atagcgaatg
     1321 taacaaaaga agatctgaaa aagaataacg ataaagatgt cagttttgac tttgatgcgg
     1381 tagaaccaat gacgacagaa ggggtcatga ggtcgcagat gagaggaaca gatctaccag
     1441 tgattgctag tatcgcagtc ccttcagttt caatcaattt accgattttc aaaggcttgg
     1501 ataatacgtc actactttac ggagcaggaa cattatctcc agatcaagaa atgggaaaag
     1561 gaaattatgc cttagcaagc catcgtgcaa cgaaccctga attgttgttt acaccgctgg
     1621 aaaatttaga gatgggtgcc aagatctatt tgacagattt agaaaatgtg tatacataca
     1681 aaacattttt taaagaaaaa gttgctccta cagataccca attactgaat gaagtcgagg
     1741 aaaaagaaat tgtcacacta attacttgtg gcgacatgga cgccgtcacg cgactagttg
     1801 tacaaggaga actggaaagt gttacaccga taaaagatgc gacagatgat atgagatctg
     1861 ctttcaatct agagacaaaa acattttagg atactgggac ataagtcgtt acagattaaa
     1921 aacagccaaa ggatatgaat cgataaggaa aaaccaattt gctgaaaaaa agaggaacgc
     1981 aaagaggtgc atctctgatt tggttgtttt ctagatagac ttgtgttcca gtttttttat
     2041 tttttatatg aaaaggcttg cataaataaa aattcgatgg tatgatgatt ttgaataaga
     2101 aatggattgt tactgtacgg caggcaaaac cagaattcag ctaagaaaca gtaggcgaat
     2161 tctaggtttt tttatttttc ttgagagggc gaagcaaaat gaaaattgat aaaattttga
     2221 ataacaatgt cgtcatttcg aaaaatggat tcggggaaga agtcgtttgt atgggaaaag
     2281 gactagcttt tcaaaaaaaa gattggggac gagatttcgc cagaagcggt ccaaaaagaa
     2341 tttattttaa gagattcttt tgctaaaaac caattccagc agctgatggc tgatattccg
     2401 gcagaggaga tcgaatgggt caaacaagta gtcgaactgg ctgaagataa actaaaagtt
     2461 gaattttcgc ctaatattta tctgacattg accgatcatc ttcattatgc gatcacacga
     2521 gcaaaagaaa atatccaact gcctaatcca ttattatttg aaacaaaaaa attttatccg
     2581 aaagaatatc aagcagcgaa agaggctctt ttgttcgtga aacaaaagac gggtgtggaa
     2641 ctttctgagg atgaagccgg ttttattgcc tttcattttg tgaatagcca acaaggaaac
     2701 gaagacatgc aagtgacgat gaccgctacc acaatggtaa gagatatact gagtatcatc
     2761 agtaaattct tcggcatcgt gttcgatgaa gaatctttga attatcagcg tatcattact
     2821 catctgcagt tttttgccca gcgttatctc aaaggggaag gatctgacga gcaagatgaa
     2881 tttctctacg cattagttca aggaaagtat ccaaaagcgt ttcattgtgt cgaacggatc
     2941 aatgagtatc ttcgacaaac gcaaaaacag gaaatgggga tcgcagagca gatttattta
     3001 acgattcata ttcaaagagt agtaagtgag aaaaaaagca tccaatcata aggattgtta
     3061 ctgtatggca ggcaaaacct ggattgaaaa aataggttca cgaatgtttg tgactgtttt
     3121 tttcaatctg ggtttttatt ttttaaataa aaaagaaaga aggaaaaaac aatggataat
     3181 caagcagttg gtcgtcgtgt atgggaagcg gtaggaggac aaaagaatgt caaaagttta
     3241 gtacattgtg ctacgcggtt gcgattcaga ttaaaagatg aatctttagc agatacgcaa
     3301 aagttaaaag aagacccgga cgtgatccaa gtcgtacaaa gtggcggtca gtatcaagta
     3361 gtgattggca gtaatgtagc agatgtttat caatcgatcg tggatgagga aggtcttgca
     3421 gtttcggagg atggaaaaga agagtccaaa aatattttga atcgtctgat cgatattatc
     3481 tctagtatat ttacaccttt tctaggggcg atggcagccg ccggggtatt gaaaggattc
     3541 ttatcattgg caacggtgat gggctggctg acagctgata gcggtactta tcaaatattg
     3601 tttgctgcag cagatggtgt ctttaccttc ttacctgtca tgcttgcttt tacagcagct
     3661 aaaaagttca aagccaacca gtttttagca gtagcaattg ctatggcact tgtgtatcca
     3721 gctatcacag cagttgctgg tgcgggagaa gctatcagtt tctttgggat cccagtgatt
     3781 ctttcaccat ctggttatac ttcttctgtc ataccaatca ttctagccgt atgggttcaa
     3841 agtaaattag agccattcgt aaaaaaagtg attccgcaat ttctgcaaat gattttagtt
     3901 ccgcttgtcg ttttagtagt gatggttcca ttaacatttc ttgctttagg accaatcggg
     3961 acggttgccg gtaatgcttt aggcggtctc ttcaactcga tttatggatt tagtccaatc
     4021 gtagcaggtc taatcatggg aagtttatgg caagtattcg tgatgttcgg catgcattgg
     4081 ggattcgtac cgatcatgtt tttgaatatc gaacaatatg ggtttgatgt attgatgcca
     4141 atgcttcttc cagccatctt ggcacaaggt ggggctgctt tagctgtagc attgcgaaca
     4201 aaagatacga aacttcgagc attagggatt tcttctacag tgacttcgtt atttggaatc
     4261 actgaaccaa ctgtgtatgg tgtgacatta cctttgaaga aaccattcat tgccgcttgt
     4321 atttctggag gtattggtgg agctattatc ggattttccg gagtaaaagc tttctccagc
     4381 agtttggtca gcttattgac gattccgact ttcattaata cggtggatgg tgtagagtca
     4441 aatgtgacag tagcagtaat agctacagga attgcttttg ttcttgcatt cgtaggtaca
     4501 ttgattttag gatttgacga acaaacacaa gacaatcaat tagaaaacaa acatgcgaat
     4561 gcaggagaac cgattacttc agcacggcat accttaaaaa gtcctttaac gggtaaagta
     4621 ctgccattga gtgaagtacc agaccaagtt ttttcttctg gcgtgatggg aaaaggtatc
     4681 gctattgatc cagaagtagg agaactagtt gcacctgcag acggagagat cacgactatt
     4741 tttccaactg gacatgctgt agggatcaca acgactgacg gagcggagat tttgattcat
     4801 atcgggatgg atacagtaga attaaatggg aatggctttg agatcttagt caaacaaggg
     4861 gatctcgtca aagcaggaga tttattgatt cgttttgaca tcgaagcaat tagagcagct
     4921 ggctatagcg taatcactcc agttgtcatt acgaatactg atgcatttgc cgatatactt
     4981 gaattagacc aaaaagagat tattgcaaac gaagatgttc tggcaattgt aaaataagga
     5041 ggaaatcagg atgcaatcac gtttttcaga aaaattttta tggggtggag caactgctgc
     5101 caaatcaatt agaaggggct tatgatcgag acggaaaagg actatccgtt gcagatgcta
     5161 tgcctggagg taagcagcgc tttgcgatta tcggcagtga agaatttgac tggacgattg
     5221 atcaagaaaa atatatttac ccgaatcatc gaggaatcga tcattacgat cgtttcaaag
     5281 aagatcttgc cttgtttgcg gaaatgggat tcaaatgtta tcgtttttcg attgcctgga
     5341 cacgaatttt tccaaatgga gacgaaggta ctcctaacga agcgggatta gaattttatg
     5401 atcagctgat tgatgagtgc ttaaaatatg atattgaacc tgtgatcacg atttctcatt
     5461 acgaaatgcc tcttcatttg gcaaaagaat acggtggctg gaaaaatcga aaactgatcg
     5521 acttctatga acgatttgct cagacagtat tagagagata cagcagtaaa gtcaaatatt
     5581 ggatgacttt caatgaaatc aattcggcct ttcactttcc agctttaagt caaggattag
     5641 taaaaagcaa tggagcagga gagtaccaaa atattttcca agcatggcat aatcaattcg
     5701 ttgcaagtag caaagccgta aaaatcggcc acgaattgcg ttcggatatc caaatcggct
     5761 gcatgattat ctatgcaaca acttacagca tcgatgccaa tccagtcaat caggcagcaa
     5821 caatgatcca aaaccaagaa ttcaattttt tctgcacgga tgtccaagta cgtggagaat
     5881 accctgcata cacagcgcgt acccataaaa aatatggagt cgatccggaa aaattagagc
     5941 aaacggaaaa agacttccag ttgctaaaag aatatccagt ggactacatc ggatttagtt
     6001 attatatgtc tacggcaatc aatgagactg atccacaagc agcaacttca gaagggaact
     6061 tgctgggagg agtaaaaaat ccgtttcttg aggcaagtga atggggctgg cagatcgatc
     6121 cagaagggct gagaatcgca ttgaatgaat tatacaatcg ttaccagaaa ccattattca
     6181 ttgttgaaaa cggtcttgga gccattgatc atatggaaga ggatggcacg attattgatg
     6241 attatcggat cgattattta cgtcgtcata tcgaagcgat ggctaatgca gtagcagacg
     6301 gtgtagattt gatgggctat acgccttggg gatgtatcga tcttgtcagt gcatcaacag
     6361 gagaaatgag taaacgttac ggctttatct atgtggatct agacgatgaa ggaaatggga
     6421 cactgaatcg atcaaagaaa aaatcttttg attggtataa agaagtaatt gcctcaaatg
     6481 gcgtaaactt gtaattaaag cagctgaatg aaaaagaaca cacttctcac atgtgatttg
     6541 tgttcttttt ttatttttta tgtgctattc ttttagtaat agtaaagcaa agggtgacgt
     6601 tatgaaaagg acacgtgtac tatacttgga agtcgcagat aaaattaaag aagatatttt
     6661 ctcaggaaaa tatccagtcg gttcgatgtt gccgacagaa agtgaattag aagaactgtt
     6721 tcaagtcagc aaaatcactg tccgaaaggc aatcgaactg ctggcatcag atgaatatgt
     6781 cgcaaagaaa agtggtcgtg ggacgacggt tctaagcaat cgtccttaca atcgattatc
     6841 caaagcggca agctttacgc aaatcttgga gaactcccga tatgaagtcc ggaaagaaac
     6901 gctggatttg caattggtcc atataaagaa ggaagatcct ttgttttcct ttttcggtga
     6961 gcaagctgtt tgttttaagc gcttatatta tttgaacaat cagccttata tttattttgt
     7021 tcattatctt ccacaagaaa tgatgcaatt cagcagagaa gaatttggca aagaatcttt
     7081 gtatcgtttg ctgacgaaaa aaggatatac tattgactca ttttctgatg atttctcggc
     7141 agtattttta acagaagaag aacaaggaat tctgaaaaca gacgcacaga tcggcatcaa
     7201 acggatacgg aaatcgtcta cgcaaattgg ggaaatgatt gaatattcgg aggcggtcta
     7261 ccatacggag ctgcatcctt accatattga ttatgaaaca taaataaaaa aagaggttgt
     7321 gaaaaagctg ccctgcatca agtaataaga acagccaaac aaaaatagct tctcatattt
     7381 ttcgtttggt taggcttatt accgcagata cacggctgtt tctggattac catttattct
     7441 ggataagggg gtgtggcacg attttcagaa ggaatctatg aaccaatcac tgtattgatt
     7501 ttagcttcga tggtaacccc attcggcttg acgatcgctt atttcttagg gaaaatcatt
     7561 cgtaaaaata tactcaatcg tcaagaaatc gatacattga agaccgcttt tcctatgggg
     7621 atctgtcaga tcacagaggg atgtttccct atcgtattga acgacttggc acgcaatgtc
     7681 atagcaacgg gagtcggtgg gacagtaggt ggcggattaa gcatgttttg gggcgcagat
     7741 agccgtattc cggcatcggg aatgtttgca gtcgctacga tgaccagacc atgggcattc
     7801 attggtgcat tgttagctgg ttcttttgtc acaggaataa ccattttatt attgaaaaaa
     7861 ccagtagatc cgaatgcaga aatcatccaa gaagaaaaag aggaagaaga catatcttgg
     7921 gatgatttga caattagtta ggagaggcag aatggattac aagaaaaaag tacaatagat
     7981 gtaccttgag acaggaatgg tatgaaagaa tcagagttag aaagaatcga atatacagat
     8041 tttggtttag gagcgatcga aactgtccag agcatcggca ccctccttga aatgacgatg
     8101 aaggaaaaat gagaaccttt cgttgtcgaa agggtctggt ataccttatg tcgaaggaaa
     8161 ggaaacaaaa aaactttcct gtactattcc aaaaaggaaa gaaagttatt atacagtaaa
     8221 aaaagaaatt attcttcatg ctagagatca gtacacgttc gagcccaata tcaaacacta
     8281 gttccaggca ggcgcaacag gtgcggttat cactgaattt tcttccagca gtgacgattc
     8341 aagtgatatt tttacaaatc cagctattta tcgttaacaa aaagattttt aggagaagct
     8401 gatgaacaaa aatgatcaaa ttttgatcgt ttagttcgtc ggctttttta tttagagaaa
     8461 catcatttat cagtgaaaca taacacgaga acaaaatgat tttttcgtta ataaaagaaa
     8521 caagtatttg ttgtttaaaa taatacacgt tattggcata taggacgaaa tcccagtatc
     8581 ttctataagt aagtcatttc atatcgatga aaacacgtta tttatttttg ttttatctat
     8641 aaaatggctg aaaaatgatt tttttctaaa tactatatat agtggcgtct atcctatata
     8701 ccactaaaaa actacaaaat ctagtctttt attttaaaaa aacacgtgta gaatgaagat
     8761 agacttttga gttagggagt gtttttttat gaaacttact gttttttgcg gttcccgttt
     8821 tggtaataaa gaaagttaca aatttattgc gcaaacgtta ggaaaataca tggcacaaga
     8881 agaaatcgaa ctggtttacg gtggttcata ctccgggatt atgggagtga ttagtaaaac
     8941 agtactggaa aataacggaa aagtcacagg tatctatccg aatgggcttt ttgaaactga
     9001 attgcctgga aaagatgtta ctacatttat tcctacagaa acgatcgatg aaagaaaggt
     9061 attattattt gaaaagggag atgctgtcct cgttttccct ggaggtctag gtacattgga
     9121 ggaattctca caacttcttt cttggatagc aatcggtctg acgcccgaca agccaatcgg
     9181 aatattgaat attggcggtt attacagcgg cttgcaacaa ttattagaaa cttttgcaaa
     9241 agaggatttt atggataaaa aatggttgga tcaagtaatc ttttccaaca atccattgga
     9301 actggtcaat gaattacgag cagtatctat taaaaatcag ttattattga aggaggcaaa
     9361 ataatgagtc aaatatattt agcaggacca tttttttcag aggagcaaat cgatcgagta
     9421 agtcgtatcg aaaaagcgtt ggaggaaaac aaaacagtca caagtttcta ctctccacgt
     9481 catcaccaag aaagcaatta tgaactattc agcgctggat gggcgcagga agtatacgaa
     9541 aaagatatgg aagaactgac aaatgcagaa tttgttgttg ctatccttga ctttgagcat
     9601 caaacaatcg atccaggaac ggcttacgaa ttaggtgtgg caactatgtt gaaaaaaccg
     9661 atgatcattg tacaagaaga gacggtacct acgaacttga tgattacaca aagtctccat
     9721 acgtatttaa aatcagacca agctgtacgt gaatatgatt ttgaaacatt gcctgttgaa
     9781 acttacgtag gcgagtactt atagaagagg aagggttgta tgtcagtgat tttgatttca
     9841 ggaacgattg gtgcaggtaa gagcagtttg acggatatgc ttgcaaaaga gattgattct
     9901 aaaccatttt atgaaaatgt cgaagataac gaagtattgc cgctctttta ttcaaatcct
     9961 gagcagtacg cttttttatt gcaaatcttc tttttgaaca agcgattttt agcaatgaaa
    10021 aatgctttag tgaacgatga caatgtgcta gaccgatcca tctatgaaga tagcctgttg
    10081 ttccatctaa acgctgattt aggtcgggta acggatatcg aagtacagca gtacgatagc
    10141 ttattagata cgatgctaaa cgagttagat gatgttgctc caaaaaaacg gcctgatttg
    10201 atggtccata tcaaagtttc tttggacacg atgctagaac gtatcaaaaa acgtgggcgt
    10261 gactatgaac agctagaaag cgatgagacg ttatatacct attatgaaac gttgaacacc
    10321 cgctataatc aatggtatga agattttgat gtatgtccta aaatacaagt ggatggggat
    10381 aaattcgatt ttgtagaaaa tccagaagat gcaaaaaagg tgatccgtca gatccaagaa
    10441 aaattagctg aattggaagg aaagcctgct ggaaaatatt ttacggataa ccagcatgca
    10501 aaaggtcaag aattaggcta aaaataaaaa accaaacgac gggaaagaaa a
//
LOCUS       DACGEU010000092        10490 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.093, whole genome shotgun sequence.
ACCESSION   DACGEU010000092 DACGEU010000000
VERSION     DACGEU010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10490)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10490)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10490
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.093"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..564)
                     /locus_tag="IXR40_002335"
     CDS             complement(<1..564)
                     /locus_tag="IXR40_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAQ4362140.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNE"
     gene            complement(569..2482)
                     /locus_tag="IXR40_002336"
     CDS             complement(569..2482)
                     /locus_tag="IXR40_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HAQ4362141.1"
                     /translation="MNSLRTKQVLKGALVILFAVSTSVPQWTVYGESISSESESREVE
                     TTETTDAGNETKSSTSQTETNTETTVETSVTSTDQETTATTDNQQTEEATATKMSNDE
                     SSSAKVSDKENGTENDDIGKGENFNGKEYLNYFGKQMTEILNGPTEDIKSKLIELLVT
                     ELAVNDYGVDKEIIKHLIATYLLYDIAFAKNSVLMSMLGGTDDGTTPTENTGFYPNTK
                     QLHQTVLNKQDGKMMDVYAYYVDQGSDKTVMIHGGFRGNWNNGIVTEEYNDFYKAGYN
                     LLFVDSRATGNSGGDYVTYGQYESDDVLYWINQEVRERPSQKILLYGGSMGAATMMSV
                     LAKDIPVNVKGIIENCGFASIDEQLRFTYSQTVAPALPDAIKNQLDIIGDQEHEDLFM
                     GLLKQYYFDQEMHLDTKAALPTIGMSDSLPKLIIHGTADDVVPVSNAQKLYELSGGYK
                     DLLLVEGAGHGKAQEVDHAAYTKHVTDFLKVVFHDQINVKYVDENNKSLLKDQDEIQL
                     YGAYGENYMTEQKTFEGYELANVEGPTEGIFNETIPTIIFYYKKIPVAPPKKQDPTEN
                     ADNKGKNEPREDQSSDDTQPIQMTVKVQKKTDAKKRMLPKTGEKKHSLLIYSGGFLSV
                     STIITWIWRRKRG"
     gene            complement(2650..3156)
                     /locus_tag="IXR40_002337"
     CDS             complement(2650..3156)
                     /locus_tag="IXR40_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAQ4362142.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            3316..3756
                     /locus_tag="IXR40_002338"
     CDS             3316..3756
                     /locus_tag="IXR40_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HAQ4362143.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            complement(3782..4939)
                     /locus_tag="IXR40_002339"
     CDS             complement(3782..4939)
                     /locus_tag="IXR40_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362144.1"
                     /translation="MRTIQRKLRELNTILKNYHLSCSLKKGNPIEGEEYRIRYFFHLM
                     YWQSFDENHSDILSSIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSI
                     TYVPEEMNKFVHPLITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYL
                     EEDLLDTPDKVQESWGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGT
                     KKKVDAFGKSAEDRDFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCML
                     VRDIFIKHEQPVIFYIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYP
                     IDKKAYDQTNTQIFYWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(4942..5298)
                     /locus_tag="IXR40_002340"
     CDS             complement(4942..5298)
                     /locus_tag="IXR40_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362145.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            complement(5596..6570)
                     /gene="sgrA"
                     /locus_tag="IXR40_002341"
     CDS             complement(5596..6570)
                     /gene="sgrA"
                     /locus_tag="IXR40_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HAQ4362146.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSEISTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            complement(6766..7605)
                     /locus_tag="IXR40_002342"
     CDS             complement(6766..7605)
                     /locus_tag="IXR40_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HAQ4362147.1"
                     /translation="MIRIIRLIGSVLIVFVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            7790..8677
                     /locus_tag="IXR40_002343"
     CDS             7790..8677
                     /locus_tag="IXR40_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rotamase"
                     /protein_id="HAQ4362148.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
     gene            complement(9271..9965)
                     /locus_tag="IXR40_002344"
                     /pseudo
     CDS             complement(9271..9965)
                     /locus_tag="IXR40_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
     gene            complement(9949..10347)
                     /locus_tag="IXR40_002345"
     CDS             complement(9949..10347)
                     /locus_tag="IXR40_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HAQ4362149.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
BASE COUNT         3142 a         2088 c         1577 g         3683 t
ORIGIN      
        1 ttcattttga agtgctaaca aatattctcc actaatttgt gcacctgccg aatttccacc
       61 aatcgaaata ttcgaccaat ctgcttgatc ttttatctct tttttagctg cttgaatggc
      121 ttcgttcaat tggataactg gtgtaggatg ttttgcttcc ggtgatcgtt cataatctat
      181 atttacgatg atttgctgcg tgtctgaaca tagatattcc aaataatcac gacaatcatt
      241 tttatcccct cctacatatg cgcctccatg catccagaaa agaatcggta attttttctt
      301 ttccactttc ggtgtgtaga tatccatatt attatttttg tactttgaag gataggatat
      361 ttcttttttt atatcgattt gttcgatttt ttgctggaaa tcatctggtc gggcatatac
      421 ttgttctttt tcacttgtgt caaattgttt tctaacaagc aagctaatcg gctttggtgt
      481 gatttgatta atcaaaaata cagtgactaa aataactacg atgataactg gtactgcaat
      541 cactattcgc ttgaaccatt tcattcattt accctctctt tcttcgccaa atccatgtga
      601 taatcgtgct aacagataaa aatccacctg aataaatgag aagcgaatgt ttcttttctc
      661 cagttttcgg caacattctt ttttttgcat ctgtcttttt ttgtactttc actgtcatct
      721 gaatcggttg cgtatcatca cttgattgat cctctcgagg ttcattcttt cccttattgt
      781 ctgcattctc tgtcggatct tgcttttttg gtggagctac tgggattttt ttgtaataga
      841 aaataatagt tggtatcgtc tcattaaaaa tcccttcagt cggtccttca acatttgcta
      901 attcgtatcc ttcgaatgtc ttttgctctg tcatataatt ttctccataa gctccgtaaa
      961 gctggatttc gtcctggtct ttgagtagac ttttattgtt ttcatccaca tactttacgt
     1021 ttatctgatc atggaacact actttcaaaa agtccgttac atgtttcgtg taggcagcat
     1081 ggtcaacttc ctgtgccttt ccatgccctg ctccttctac taataaaaga tctttatacc
     1141 ctcctgataa ctcatataat ttttgcgcgt tagacacagg tactacatca tctgctgttc
     1201 catggataat caatttaggc aatgaatctg acattccaat cgtaggtaga gcagcttttg
     1261 tatccaaatg catctcctga tcaaaatagt attgtttcaa aaggcccata aataaatctt
     1321 catgctcttg atccccaatg atgtctaact gattttttat ggcatccggt agtgcggggg
     1381 ctactgtctg gctgtacgta aaacgtagtt gttcatcaat tgatgcaaat ccgcaatttt
     1441 caataattcc tttgacattg acaggaatat ctttcgctaa tacagacatc atcgtagctg
     1501 ctcccatcga accaccataa agtaaaatct tttgagatgg ccgctctcga acttcttgat
     1561 ttatccagta aaggacgtca tctgactcat attgtccata ggtcacataa tcgcctccgc
     1621 tattaccagt cgctctggaa tcaacaaata ataaattata cccggcctta taaaaatcat
     1681 tgtattcttc tgtaacgatc ccgttattcc aattccctcg aaatccgcca tggatcatga
     1741 ctgttttatc tgaaccttga tcgacataat atgcatatac atccatcatt ttgccatctt
     1801 gtttgtttag tacagtttga tgaagttgtt ttgtatttgg atagaagcct gtgttttctg
     1861 taggcgttgt cccatcatct gtacctccaa gcatcgacat caacacactg ttttttgcaa
     1921 aagcgatatc gtacaataga taagtagcaa tcagatgttt gataatctct ttatctacac
     1981 cataatcatt aacagcaagc tcagtgacta ataactctat taattttgac ttgatgtctt
     2041 ctgttggtcc attaagtatt tctgtcatct gtttaccgaa gtaattcaaa tattctttac
     2101 cattgaaatt ttcaccttta ccgatatcat cattttctgt cccattctct ttgtcactta
     2161 ctttagcaga agaggattcg tcgtttgaca tttttgtagc tgttgcttct tctgtttgtt
     2221 ggttatctgt ggtagcggtc gtttcttgat ctgtgctagt aacagatgtc tcaaccgttg
     2281 tttcagtatt tgtttctgtt tgtgaagtac tcgatttcgt ttcatttcca gcatcagtag
     2341 tttctgtggt ttctacctcc cgagattccg attcggaaga aatgctctct ccatatactg
     2401 tccattgcgg gacgcttgta cttacagcaa ataagatgac caacgctccc tttaatactt
     2461 gttttgttct caagctattc actccttttt atgtttctag gagaattata tgtaaacgca
     2521 aacatttttt atacaaaaaa taaatggttt atcccataaa aatagaacag gattattttc
     2581 tcattttacg taataaagca gaatggataa accagtatcc attctgcttt ttttaaacga
     2641 agaaacaact tattgctcca aaaatgtcag aaatcgttta tcccaaattt tctcgtaaaa
     2701 agcgattgtt tcctttgctt tcataaaagg attatcataa gttgtcgttg ctcctctaca
     2761 catcataagc tggtatccta atccatgagc aaacttcaca gtcgtatcta tacaatactc
     2821 tgcttgtgcc ccacataatt cgatcgaatg acagtccaat tcagttaata aaacactcaa
     2881 attagtctta taaaatgaat tcgcatgggt ttttctcaca aaataactgt gctcaggaat
     2941 agataattcc gacaatagct cccatggttt tgtttgtggc actaattgag catcttcgtg
     3001 ttgaacgaaa ataactggtt tcccaatcgt ttcgtatgtt ttgattcttt tattcactaa
     3061 tgctgtcact gtttctaatt cgtgtatcgg cgaagaatca aaacataccc ctttttgtaa
     3121 atcgatcact actattgcgt cggctgtgtt tgacatactt gtgccttctt tcttttttct
     3181 tgatttaata gtatttctta tctagctagt tccattatac gtgacaacat tttcttattt
     3241 tacacctcta aatggcactt ttcgactatt tcttcatgtt attatttcat aaatacttag
     3301 ctattggagg aatgtatgat gattaaattg tatacaggtt ctggctgctc gtcttcaaga
     3361 cgcgcaaaac gttggcttat cgtccatgat ataccgttta tcgaacagaa cttaattcgt
     3421 caaccactaa ccaaaaatga atttatccac ttactaaaat tgacaaacaa cggcgtgacc
     3481 gaaatgctct ctactcattc tattagttat aaaaatcttg ttcacagaat agatgaactc
     3541 agtttgagtg aactatatat tgagattcgt acatcccctt ctttattgaa aaaaccgatt
     3601 atctacgacc aatctgcaaa acttttgact ggatttagcg aagataaaat caggatgttc
     3661 ctttctaaaa ctaaaagaaa gcaagagctc aacgaactct tgctttctgg tcatcttgtc
     3721 gattttaaag aaaataatct ttttgcaatg tcttaatttt ggcataaaca atctgctttt
     3781 cttaattaac gaaatccaat ttttccaata tggatctatt tttctcattc ctgattttta
     3841 tgatttcagc tttcagacgc gcccaatcat tttttgtagg ttgtccattc cagtaaaata
     3901 tctgtgtatt cgtttgatca tatgcctttt tgtcgatagg ataatcgcta atgacaatat
     3961 caggtaactg atcagcggat gcactatatt ttattgggcg ttcagtcata gataatatcc
     4021 ttttctttgc ccataattcc tgtgttttac catactttga ttgaatatag aatatgacag
     4081 gttgttcgtg ttttataaaa atatccctga ctaacataca gtattgaaaa atcaaccgtc
     4141 tgttcttttc ataataagta ttaagctctg gaattctgcg agctacccca ctaaaaaact
     4201 gttgcatgat tggatacatc actggaaata tatgctgaaa atctctgtct tctgctgatt
     4261 ttccaaaagc atccaccttc ttttttgtcc caaaaaccct tgaatacaaa tggatcattg
     4321 ccaaattgac atatagataa tttttttctg aagttgtaaa acaaatcttg aagttttttt
     4381 caaaattttc tacaatagac gattcaatcc agccccaact ttcttgtact ttatctggag
     4441 tatccaacaa atcttcttcc aaataggtgt tcattacacc aaacataaaa taaaggtaag
     4501 cttgctctgt tggagtgatg tgattcatcg accagaagtt tgcttcaaaa aaaggctcta
     4561 gtatgtaatg cgtaaactct tcttttgtta tcaatggatg cacaaatttg ttcatctctt
     4621 ctgggacata cgtaatcgag tggccttgtt tcattcgttg caacgaaatt cttagtaggc
     4681 tgatccattt ctttctatct atactacgcg tatatggcgc atgtttcgca aatttttcta
     4741 atagttgacg tttatttttt atacttgata atatatcaga atgattttcg tcgaatgact
     4801 gccaatacat caagtgaaaa aagtatcgga tacggtattc ttctccttct atcggattac
     4861 cttttttcaa gctgcaagat aaatgatagt ttttcaaaat agtattaagt tctcttaatt
     4921 ttctttgaat cgtacgcaaa cttatataat tttttgacta agattttcta aggattgata
     4981 agtacctttg taaagtgaat ccagtaaaat ataaccaatc gttccctcta aaagtataga
     5041 ataaacttta ctcagtaaaa actgagaaga aaactcgact tttatcatct tgttttctga
     5101 aagaaaagat aatttatatt ctggatacct ttcgcaaaac gattctgctt gttgaatcac
     5161 cgaattcatc ttagccaggg tgtagtttag atctaaagcg atatccttca ccacatataa
     5221 tttctcgtct ctttcataac aatagttcaa aaattgatat acttgccttt cattgatatc
     5281 aataaattct tcaaacaaag tacatactcc tttttatcta ttatttagac ttattccgac
     5341 agctacatga ataacgtaca aatagattcg ttactgattt ttcagagata ctaccatgcg
     5401 cagtgtgcat tgtcaattat tcttgctctt attttccatt tgtgttcctg ttatttcctg
     5461 tttctcaaat atgttagtaa acaaaaatag atctggcaaa gctacaactt cgccaggcaa
     5521 tacagcactc tcgaatgaaa tattcactca aaaatctatc gttttattca attttagatc
     5581 tgttgctttt attctttatt tcactcgatg gaagagagaa cgaaaatagc ttgctcctac
     5641 aatcaaaatg agtaacacac ccatccatgt aattagcttg ttcaaggttc tactaccagt
     5701 ttctggtaaa tcgctttttc tattatctgt ttctttcgct ttttcttgat gatcaattcc
     5761 acgagaaaca aaatcaggct gttttagcac actttttagg ttgctccctg catttctctt
     5821 ttgttcctta gttggtatga taggtaccaa atcaagttca ttatttactt ttcctgtgct
     5881 gctttcgctg ctcgtgcttc ctgtgctact ctcactactc atgcttcctg tgctactttc
     5941 actactcgta ctctccgtac tgctttcgct gctcgtgctt cctgtgctac tttcactact
     6001 cgtactctcc gtactgcttt cgctgctcgt gttttctgtg ctaatttcac tgctcgtact
     6061 ctctgtactg ctttcaccgc tcgtgttttc tgtactgctt tcactacttg tgctatccgt
     6121 actgcttggc ggtccaacaa ctgtccaact gcttggtttc aaattctccg tgatcgtcat
     6181 ctgtccatca taaaaaacaa tcaaatcaac tttatcttta ctcttgatct catcaatcga
     6241 tagttctgca gaaatcatta ttgtatactc aataccagcg gtccattgta cgtcttttaa
     6301 ataaacttcc ccaataactt tttctgaact tccattacca tcccaaccat atgttagaac
     6361 agcatgtaca tcactagcat tcacgctttt gtttggtttg actggaatag taatgacttg
     6421 ttgtgtcatg tcataaacaa tccgatcagt tttcacagta aatgaaagat tctcatttgc
     6481 ccgttcattt gcagaagtac tgattccaat cattgctgca attatactca gcccaagaat
     6541 aacaaataat acggtcgctg ttttcttcat ttctatcact ctccatataa ttaccttcta
     6601 tttgataaag gaattatata aaatgaaaat gatgagaaca cgacagtcag ttgtgaaaat
     6661 ctaacaaaag atgtcgtgta ttcgcttgaa tttgtttact ttttcgttta atcaatgaca
     6721 gacttaaaaa agcaagaccg atatcagcct tgctttcttc atcttttatt gataaacagc
     6781 agtgtatttc ttcatccgct ttgttttata tgcatagagt aacaaaccaa caatcaagac
     6841 taacaagaat aatgtagttg atatagatgc ttcagcccca aagtttcccc cagtaattat
     6901 tgtattttgc gattggatca gagtggagaa aaaaccttgt tcttgcgttc cgctgactgg
     6961 tatacccaaa atagctcctt gtgtccaatt ccaagtaata tgagcaccaa tagccgtaaa
     7021 taaacttcct gtactgtaga taagtgcgct gaaaaagcaa cctgctaaaa agatattgaa
     7081 aactgccaga aatgtcatgt taggattcaa tccgtgcaaa agagcaaata atgcagcaga
     7141 tccaatcatt gctattaacg gaccaaatct aagcatctga tgctgaaaaa agccacggaa
     7201 taaaagctct tctgatgccc ccactgcaat aaataaaata aaactcgtta tcagcggcac
     7261 aatgtttgcg tttcctgaat ctaaccgata cgcccccgtc aaatataatg gactagtaat
     7321 aagcagaaac actccaattc caacaacgag acctcccgct aaataccccc agtcttttcc
     7381 tcgaacagaa acaccataat cttctattct ttttccttcg accttactag caagaaataa
     7441 agctagtaaa aaaacagcta aatgtccgac cgtaccggca attgctccaa tccattcact
     7501 atttccaata aacatatccg caagtgcatt attgacaaga attcctaaaa caaaaccaac
     7561 aaagactatt aaaacagatc caatcaaccg aataatcctg atcatctttc atccctcctt
     7621 tatattaagt ttaacaaccc ttttctttct tgtctcgtga aaactatgta aatgttctcc
     7681 atcatagaga gaatagattt ttacgaacta agaatatcta cagcaacctt acgaaaatga
     7741 aagactgtct ccctaattct tctgttagac tgtttttaat aaggaaagga tgggaaattt
     7801 tttgaaaaaa caactactaa ttatgtgcct ttcagcatgt gcaattttac tattctcagg
     7861 ttgtagcaag tccaatgaaa cgattgcaac gtttaaaggt ggaacactta cagttcagga
     7921 tttttatgat aacccaaaag ttaaatcaaa taatcaaaca ctattaaaaa aaatgattgt
     7981 cttcaaagca tttgatgatg tatacggaaa agagatttct tcaaaggaag taacaaaaga
     8041 atataatgaa caaatcaaaa aactcggtcc aaactacaag gaacaattaa aagcagttgg
     8101 ccaaacagaa gagacatata agaaactctt taaacagatg ctggctttcc aatacggttt
     8161 gaaagccaat gtaaaattaa cagataaaga tctagacact gcttggaaag aattctatcc
     8221 agaagttagt acacagatca ttctattttc gactaaagaa gaagcagata aagcaaaaaa
     8281 agaagcaaat gaaggagaaa atttctccaa gcttgttcaa gcttatggaa aaaataaaac
     8341 attaaaggaa actgatggaa aaatgaattt tgattcaacc aatccagaga ttcctactga
     8401 agtaaaaaaa gcagcattta aactaaaaaa cggggaagtt tctgatatca ttcctgtaac
     8461 agatccaacg acttatcagc aaagctatta tctagtaaaa atggtaaaaa aacaggataa
     8521 aggttctaat aaagacaaat acaaatctga gctagaaaaa attgctaccg aagcaaaaac
     8581 tcttgatacg gaattcatgg ataaaacaat ccgtaaagtg atgaaaaaag acaatgtaac
     8641 tattaaagat ccttatgtaa aaaatatatt caaataaaca aatttgaccc aattggggat
     8701 gtggcaaaat ttgagaagtg atttttggaa attccttctt atttttgagg caaaccactt
     8761 ttgccacaac ttcatcgggg ccttttttta tttgtaccaa aacaaatcac tggatttgtt
     8821 acaatcatga ggatataatt taaaaaagtt ttttatttct atcacatgaa tcaatgcgcc
     8881 attaagtaga ttctttcatg cttccctatt ttttcacttg ccgtatcgct tcaaaaacaa
     8941 ctatcataaa ctcaaactcg actgaaaagt tattttaaaa aagactaaaa atatcccttc
     9001 tggacttgtt cttcttattc tgttatacta gagaaacacg aaagatattt ttatgcgaca
     9061 cttttcattt gtttttatga aatttattca aaactggcgt aacttcagag ttacaaggat
     9121 gtattagagg ttagggaata catcgtttaa atgagaaata agtaatagtt agtaatagtc
     9181 acccaaactt taaattaatg aatattgaat cgtcagatag cctcctcgag ttttcgagaa
     9241 ggctatcgtt tattttatgg agaaattgat tcagaagtaa tcagcgacct tttttagttc
     9301 accaatcgtt tctgcttgga aagtttgcac ccaatcttct tggaagcccc tcactgcttt
     9361 atcaatcgag ggcatctcta atacttgatc tagtagctct ttacctaacg ttatcgctga
     9421 gctccagatc gaatggctgt agtgacttgt tcacaatttt tgaaactagc tgctaatatt
     9481 tttgttggtc tttgcgtacg ttcgatctca gtccgcaacg aatcaatcac tttcatagca
     9541 tcaatgcctt gattttgcat cctgttataa taaggtgcaa tataatctgc tccattatta
     9601 atagctaaat acccttgtaa ttctgtgtaa atagctgtac cggtaatcaa ataaccttct
     9661 tttttcaact ttttgatcgc ttgaaggcct gcttgattca ccggcacctt gataaacgta
     9721 tcttttccca gttcttctat gataactcga gcatcctcta tcatttcttc ttccgttctt
     9781 cctattgtct gaatatggat aggaatctgt ccgattattt ttttgatttc tttcatatgc
     9841 gagaagaagt ttgacgctcc ttcttttttc agaattgtag gatttgttgt tacgcctgtt
     9901 aaattcaaaa actgttgaca agaataaata ctttttgtat ttgctgtatc aagcatgatt
     9961 tccatatagc tttcccccat tctgatcctc ttgatcgatt ttaatgattg tcccctttct
    10021 taaatgcggc atttccttat cttctacata cattgttcct ggaagttccg gctcatgaga
    10081 tccatcaaat tttatcgtga tatgtcctaa ttcattcaaa ttagtttgga caacatctcc
    10141 tactgctgtg attacataca tttgtttatc aaaacagagc ttcatatcac aagttatttc
    10201 ttttcttacc tgattcaatt caatcttata acaataatct gttaatgttt ccggtgcttc
    10261 atctccaaat aaaatcatta ttttttcttt cctgaatact tctgcttcta taccaacatc
    10321 tgttacaacc gtttcaaaga tcgtcatctc tgttcctcct cgtaaaatat catttgtcta
    10381 atagttttta ttcaaaatgt ttctagatta taaaatttat tgaataacac attcctaacg
    10441 gaatttgttt cgatattgtg tgatttctca gagtacaatg gatgtatgga
//
LOCUS       DACGEU010000093        10068 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.095, whole genome shotgun sequence.
ACCESSION   DACGEU010000093 DACGEU010000000
VERSION     DACGEU010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10068)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10068)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10068
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.095"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..555)
                     /locus_tag="IXR40_002346"
     CDS             complement(<1..555)
                     /locus_tag="IXR40_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAQ4362150.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGKLDDSS
                     SYCEHCRSVRIIRNGSYTTRTQMLKVKEKLTILELKRTRFLCHDCGRTFSAKTDLVDE
                     HHQLTKELKQVILMELYENQSRKLIAKKYFVSDGTVTRILREATKHYQPRMNFLPTVL
                     CMDEFKSMNSVSGSMSFICVDGTTN"
     gene            828..3299
                     /locus_tag="IXR40_002347"
     CDS             828..3299
                     /locus_tag="IXR40_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAQ4362151.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGYQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKMIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            complement(3402..5138)
                     /locus_tag="IXR40_002348"
     CDS             complement(3402..5138)
                     /locus_tag="IXR40_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HAQ4362152.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSGFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDNADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(5135..5839)
                     /locus_tag="IXR40_002349"
     CDS             complement(5135..5839)
                     /locus_tag="IXR40_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4362153.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            5970..6473
                     /locus_tag="IXR40_002350"
     CDS             5970..6473
                     /locus_tag="IXR40_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HAQ4362154.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            6433..6771
                     /locus_tag="IXR40_002351"
     CDS             6433..6771
                     /locus_tag="IXR40_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HAQ4362155.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            6792..8210
                     /gene="ffh"
                     /locus_tag="IXR40_002352"
     CDS             6792..8210
                     /gene="ffh"
                     /locus_tag="IXR40_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HAQ4362156.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            8322..8900
                     /locus_tag="IXR40_002353"
     CDS             8322..8900
                     /locus_tag="IXR40_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HAQ4362157.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            8904..9425
                     /locus_tag="IXR40_002354"
     CDS             8904..9425
                     /locus_tag="IXR40_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAQ4362158.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(9504..10058)
                     /locus_tag="IXR40_002355"
     CDS             complement(9504..10058)
                     /locus_tag="IXR40_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HAQ4362159.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
BASE COUNT         3240 a         1869 c         2083 g         2876 t
ORIGIN      
        1 attggttgtc ccatcaacac aaataaaact catggaacca gaaacagaat tcattgattt
       61 gaactcatcc atacacaaca ccgtcggaag gaagttcata cgtggctggt aatgcttcgt
      121 tgcttcacgc aagatccgtg tcaccgtccc atccgagacg aagtacttct tagcgattag
      181 tttacgtgat tgattttcgt acagttccat gagaatcacc tgcttcagtt cctttgttag
      241 ttgatgatgt tcatcaacta agtccgtttt cgcagaaaag gtccttccac aatcatggca
      301 gagaaaacgg gtacgtttta attctaaaat agttaacttt tctttgactt tcaacatctg
      361 agtgcgtgtc gtataggaac cgttgcggat aatacgaacc gatcgacagt gttcacaata
      421 ggaagaagag tcatccaatt ttcctttaat aaactgcgct tgaacgcctt tatattcttt
      481 ttcaatcagc cattcttcat caaaaaataa atgtttatct gttaatccga gtaattttct
      541 agtatgatta tccattgaga gactcctttg gtaggatgac gttttggtcg actaaatttt
      601 accaaaagtg agtctctttt tgagttgaaa cgaagaaaaa gtgttagtag aaaatcgcct
      661 tcgattttcc accaacacaa aatattatag aacccttttt ttttgctata tgacaggaat
      721 gaaaggtgtt tgcaagctta atgtgaggaa cactttccat atctgttcta tactggatag
      781 gagaagtttg gaaatatcca gaaaacgaaa tcaatcgagg tagccacatg aagaataaat
      841 ggataaatcg aagtaaaaaa aagaaagtaa cacaaagatc atcagataaa gtcatccgtc
      901 tttttccatc gtataaagaa ggattaacgg cagatcaagt caaggaacga atagaaaaag
      961 gtgcagcaaa taattcagtc gatcccacat tcaaaacaaa tcagcaaatc gtattggaaa
     1021 acatatttac gtatttcaat ttgatctttc ttatcttagc cattttgctt tgtttagtag
     1081 aatcctataa gaacttgact tttttaccag ttatcatagc caatacagga atcgccattt
     1141 ttcaggaaat tcgatccaaa aagatcttgg acgaactaaa tgttttaaat acagcaaaag
     1201 tcaatgtcat acgagacggg atagaacaaa caatagatat agaagacctt gtaatagatg
     1261 acattgttat tttagagact ggatatcaaa ttccagcaga tgcagaggtc gtggaaggga
     1321 aactgcaagt taatgaggct ttattgacag gcgaagcaga tgaaataacc aaagaaatag
     1381 gtgatccatt aatgtccggc agtttcattg tttccggaaa agcttacgcc cgattagaca
     1441 aagttggagc agattcgtat atttcccagc tgacagtcaa agccaagaca atgggagaag
     1501 gagaacagtc ggagatgatt gcttctctta atcaattgat caaatggatt gggatcatca
     1561 ttattcctat cggtatcctg cttttttctc aaagttactt ttttaatgga aacacgatca
     1621 aagaaagtgt cgttgcaatg gaagcagcat tgatcggtat gatacctgaa ggactgtact
     1681 tgctgacgac gattgcatta gcattaagtg cgactaaact agcaaagcaa agagttcttt
     1741 tacacaatat gaaaagcatt gagacattgg caagggtaaa tgtcctttgt gtagataaaa
     1801 caggaacgat cacagaaaat aaaatgtctg ttcaaaaaat gatcgtctct aaaaaacaag
     1861 aaataatcag tcagtcagat caattggaag catgcattgc tgactatgca aaagcgatgg
     1921 caggagacaa tgcaacaatg gaagctgtta aagcatattt tacaaaaacc actgatcaat
     1981 cctatcacca tgttattcct ttttcttctg tccaaaaatt cagcagtgta gcgttggcag
     2041 acaaggtgta tgttttagga gcgcccgaaa tggttttgcg cgatcaattg ccggaatatg
     2101 cggaagagtt tgtttctttc gctgaaaaag gctatcgcgt gttggtcttt ggtgtgtacg
     2161 atgggattct tgaagaacca gtattgacag aagcagtcac accattaggc tatattctga
     2221 ttgctaatcc tatcagaaaa gaagcaagag ccacatttga ttacttcaaa aaacagcaag
     2281 tagccatcaa agtgatttct ggagataatc cgctcaccgt atccaatgta gctgtccaag
     2341 cagggatttc acatgctgat cagtacgttg atgcatctaa attatcagaa gaagaatatg
     2401 aagcagctgt cgaaaaatat acagtttttg gacgcgtcaa gccagaacaa aagaaaatct
     2461 tcgttcaatt gataaagcgt aacaatacag tagctatgac aggtgatggc gtgaatgata
     2521 ttctagccat gaaagaagca gactgcagta tagcgatggc ttccggaaat gaagccgcca
     2581 tgcaggcctc acaagtggtc ttacttgatt ctgacttttc acgcatgcca gaagttgttg
     2641 cagaaggacg gcgcgttgtg aacaatattg agcgatcagc cagcttgttt ttagtgaaga
     2701 atattttctc ctttttgctc tcactgtttt cagtgatctt tgctctgacc tatcctttag
     2761 aaccatcaca aatcacattg attagtttgt ttactatcgg acttccatct ttcttgcttg
     2821 ctctagaaga aaacaaaaag cgaatcagag ggaaattcat catgaatgtg atggaaaaag
     2881 ctgtgccagg tggactaaca gatatgatcg tagtcggtgc gttggtgatc tgcggggtga
     2941 ctttgaatct aaataaaaca gatgtttcta cagcatctac catgcttttg attgcagtag
     3001 ggttcctcgt tctctataaa atctgttcac cgctgaataa attcagaagt cagatcattc
     3061 ttttctgtgc tagcggtaac tttttttcgg tcatcttttt gcataagctg ttttcaatca
     3121 ccggtatctc agctgtatca cttttgctgt tgagcattct atttttctcg gcagattcga
     3181 tttttaggca tttgaccaca ttggtagaat atttgtttga acgtaaaaat gaaaaagagc
     3241 aaaagccgtt tagtcgcgta gctaaaaaat ttctatcgat atttaaacga gaaaattgac
     3301 gaaaagtatc tcaaaaaaga gtaaaaaaga acaaccactc gtgtatcttt cgaagcagga
     3361 tgagtcatcc aactttaaaa cgcacgagca gttgctcttt tttacatttt cggaatggta
     3421 acggtgaaag tcgaacctgt tccaagatga ctgtctacag taatcgtacc attaaggagt
     3481 tgcacgtagt cttttacaat cgctaaccct aatccggtcc cgcctgaatg tcggcttcgc
     3541 gccttgtcta cgcggtaaaa acgctcaaag atccgttcct gatcctcaat gtcgatacct
     3601 ataccaaagt cttggacaga aaacgataga tcatctgttg cctgatagcg gataataatc
     3661 tcgctgtcgc tttttgaata ttggacagca ttttcaatta gatttttgat aattggataa
     3721 aggatatctg ttttagtagt aaatggttcg ttctttccaa tcaatcgaat cgtcaaccgt
     3781 ttcttttcga tgattggctg ataattttga acgatttgct ggaaataagg ttctgtataa
     3841 attgtctgga tctcgtaaga attctcgcca tcttttgaca gctggatgat ttcccgaatc
     3901 agtttatcta accggatcgc atctttttgc atgatctcaa gaaaagaagt cagagtttgc
     3961 gggtcatctt ttgcaccatc cagtaaagtc tcggtaaaac caatcagtga agtcacagga
     4021 gtttttaatt cgtgagagac gttgccaacg aaatcctttt gtagcttttc taaacgtcgc
     4081 actttcgtta agtcatacgc cacccctaga atctgtccgg taccttctga attagtaaag
     4141 tagcgcaaac tcaagtctaa tgtctgccga ccttctgtaa gggtgatctc ctgatggatc
     4201 agcggatgct caggagtcac ttgatgaatc agctgaatga gttttggctc ttgaatgact
     4261 tctgtgtacc gctgttcagg ttgatagctt accacgttta aatgtagctg catctttgga
     4321 ttaagcagta gtaaacgaga atcagcatta tcaatcagga atacgccaat catcagttcg
     4381 ttcagtaacg tatataattg ctcttctgtg gtagtacacg cccgatacat cttactcatt
     4441 tgttcgctca acgcattaat cgtctgatac aattcttccc attgatcggg tgtttgcatg
     4501 attacttccg cctgattagg attttgcacc atttttttta gtacgggcag cacggttttc
     4561 aatggctggt ttttttgata gatcagataa tagatcattc ctgcaagaac aaggaagaaa
     4621 gacagaaaga agaaaaagac ccaacggcga aaactctcag ttctcggtaa aaaaccgctt
     4681 gtcggttctg cgatacgtaa aatggcttct aactggccac tttttttgac tggtaatgcg
     4741 acatataaaa gatcctcatt caaagtagta cttttgcgca aagcgctacc taggttccca
     4801 ccattcaata cggctttgat ttcgggacgg gagtttcgct gttcattcaa tgtttcattg
     4861 tttgtgtcaa ataagatctt tccagtagca tccattaaag taatccgttc gttcgactga
     4921 tggacgaatt cttccaaagc agttttgttt tgcgctgctt ggaggttttc gacatctaat
     4981 tgccggatca gcagttgtgc tttttttgtc aggtagcttt cttgctgttc cacgatctgc
     5041 tgttgaaaat aatgggaaat caattgccag ccaccaaaaa acaaactaac taaaagaata
     5101 agaaagaaga gacgttcata aatttttttc catttcatcg tttgggttcc tgaaacttat
     5161 agccaaatcc tctaatagtc accaagtact ttgggtgttt tggatctcgc tcgatttttt
     5221 ctcgcaaatg actaacgtgt acatctacga ttcggctttg tcctgcgaag tcaaaattcc
     5281 aaatgcggtc tagcaatgtg tctcggtcga tcacacggtc ttttcgtttc atgaaataaa
     5341 caagtaattc aaattctttc ggtgttagtt caatcagatg gtcgtctacg gtcacttgat
     5401 aattggtcaa atcagcagtg atttgtccaa tcgatagata ttcaggctca gcttcatctt
     5461 ttgattgctt acgaggttca attcgtctga atattgcttt catacgggct aatacttcgc
     5521 gaggactaaa tggtttggtc aaatagtcgt cagcacctat ttctaggcca atgatccgat
     5581 ccacttggtc atctttagcc gtcagcatca aaatcggtgt ttcatttttt tcttgacgca
     5641 gccgctgagt gatctccatg ccatccatcg ttggaagcat cacatctaaa atgatgaaat
     5701 caaatgattg ttctaatgct aattctaatc cttcgcctcc atctgtggca ctggttacct
     5761 tgtagccttc tttttccaaa ttgaacgtca agagcgttac aatagaaggt tcatcatcaa
     5821 caactagtat ttttttcatt caaatctcct ttaaataggt ttcattctgt ttatatttta
     5881 gcatagaatc agtacaaagg gctattttac aaaagaaata aatggtataa taggaaggca
     5941 ctttgctgaa tagaaaggaa gagcagtcaa tgattggaat cagtgcatgt ttaggcggtc
     6001 tggcctgtcg ctatgatgga cagaaaaaag aagtaccaga attgatggaa ctagttgaaa
     6061 ctggagaagc tgtcatggtc tgtccagaag tgatcggcgg attaccaatt cctagagatc
     6121 ccgctgaaat cattggtgga aatggattcg atgtgtggaa agatcaagca aaagtatgga
     6181 cgacaagcgg cgaagatgta acggaagcgt acaaaaatgg cgcgatcaaa gcctatcaaa
     6241 aattgcagga aaaacacatt gatctagtca tcatgaagga aaaaagccct tcatgcggaa
     6301 cccattcgat ttatgacgga agtttttccg gaataaaaaa aaatggtgcc ggagtggcta
     6361 ctgcttattt tattcagcaa aaaatgactg tgctctctga tgaagaatgg ctgaaaacta
     6421 gaggtgagca gaatggaaat cgaaaagacc aatcgaatga acgcgctctt tgaattttat
     6481 tcgaccttat tgacagaaaa acaaatgaac tacatggaat tatattatgc agatgatttt
     6541 tcattaggtg agatcgcgga agaatacgaa gtaagccgac aagcagtata tgacaatatc
     6601 aagcggacaa gcaagatctt ggaggattat gaaaaaaaac tccatctttt ttctaattat
     6661 attgttcgag aacaggtatt ggaaaatatg actgcatata ttacagataa gtacccggaa
     6721 gataaaaaac tacttgaata tgtacagcaa attcaagcaa tcgaagaata aataaaagga
     6781 atgaagaaaa tatggcattt gaaagcttaa ctgaacgtct ccagcaggcg atgggaaaaa
     6841 taagaaaaaa aggaaaagta tcagaagctg acgtaaaaga aatgatgcgg gaaatccgcc
     6901 ttgccttact agaagccgat gttaacttgc aagtagtcaa agattttact aagcgcgtac
     6961 gcgaacgtgc ggtaggggca gaagtgctgg aaagtttatc acctgcacaa caaatcgtaa
     7021 aaatcgttga tgaagaattg acgatcacac ttggttctga aacagcagag ttaaataaat
     7081 caccaaaaat accaactgtt atcatgatgg ctggtcttca aggggcaggt aaaacgacct
     7141 ttactggtaa attagccaat tatttaaaga aaaatgaaaa tgctcgtccg ctcctaatcg
     7201 caggggacgt atatcgacca gctgcgatcg accaattgaa agtattaggt caacagctag
     7261 acgttcctgt atttgatatg ggaactgaag tcagcccggt agagatcgtc cgtcaaggga
     7321 tggagttagc aaaagaaaag aaaaacgact atgtattgat cgatacggca ggacgtctgc
     7381 atatcgatga aacattgatg gatgagttga aacaaatcaa agaattgacg caaccaaatg
     7441 agattttgct tgttgtcgat gccatgactg gtcaagatgc cgtcaacgta gctgatagct
     7501 tcaaccagca attaggtatt acaggggtcg tcatcactaa acttgatggg gatactcgag
     7561 gcggggcagc actatcgatc cgctcagtga caggcgcacc aatcaaattc atcggttctg
     7621 gtgaaaaatt gactgactta gaagtattcc acccagatcg tatggctagc cgtatccttg
     7681 gtatggggga tatgctgaca ttgattgaaa aagcgcagca agactacgac gagaaaaaag
     7741 cggaagaact tgcacagaaa atgcgggaaa attcattcga tttcaatgac tttattgaac
     7801 agcttgatca agtgatgggt atgggcccac tggaagatct aatcaaaatg atcccaggaa
     7861 tgaatcaagt ccctggaatc gaaaacgtca aggtagatcc aaaagatgtt gaacgcaaaa
     7921 aagcgatggt ttattctatg acgccagcag aaagagcaaa tcctgatctg ttgaacccaa
     7981 gccgtcgtcg ccgaattgct gccggttctg gaaacagtgt tgttgaagtg aatcgaatga
     8041 tcaaacaatt caaggaatca agaaaaatga tgcagcaaat gtccaaaggg gatatgaaca
     8101 tcccaggtat ggaccaaatg tttggttcag gcgtcaaagg aaaactaggc aaaatggcga
     8161 tgaatcgaat gatcaagaaa aataagaaga aaaagaaaaa acggaaataa gatgaaaaaa
     8221 acagcttcgg tacagactga aaatgtctac tgccggagct tttctatcag caatttttat
     8281 tctttactaa tacaattact ctaaacgaag aggtggcaca gatgagatgt ccgtggagtg
     8341 aacaaacaga aagtatgcgg caatatcatg atactgtctg gggtgttcct gaatatgatg
     8401 accaaaagct gttccgaaaa ttgatgcttg atattaatca agccggattg agctggcaga
     8461 cgattttaaa taaaagtgaa gcattcgatg aagcatatga tcgattcgat atcaaaaaag
     8521 tcgcaaatta tggagaaaca aaaatcagtg aactaatgga aaacaaagga attattcgta
     8581 accgaagaaa aatcgaagca gccgtccaaa acgccaaagc agtcttgaaa attcaagaag
     8641 aaatcggcag tttttcagag tatctttggt cgttttctaa tggaaaaatc gttgattctt
     8701 cttatcattc acaagaagaa gtcccaacaa caagtcctct ttcagatgaa ttagcaaaag
     8761 atctaaagaa aagaggattt aaatttatcg gaagcacaac aatctatgct tttttagaag
     8821 ctgtcgggat catcaatgat caccttgaca gttgtttccg caaagaagag gtcgtacgta
     8881 tcggcagaaa gggcgaataa agcatgcgaa aaatcatatt ttatggtgct ataagtttag
     8941 atggctattt ggcaacgaaa acggatgatc ttcaatggct ttttgacact ccaacaggta
     9001 agcaaactac ttatgaagct ttttatgaaa caatcgatac gaccatcatg ggcagaaaaa
     9061 cttatcagga agcaaaaaaa tatttggaga ccgaagcaat ttatccagag aaaaagaatt
     9121 tcgttttttc cacccacgca caattacaat tgccagatgc tgaggtcgta aacgaagatc
     9181 ctgttgcttt tctaaaaaat ctacaaatga cagaaggaaa agatatctgg gttgtgggtg
     9241 gcggtcgatt gatcaaaccg ctattggaac atcaaatgat tgatgaatgg tatatccaga
     9301 ttacccctgt attattaggg gacgggattc ctttattcca aaaaggaaca tatgaagcgc
     9361 gttttgaaat gctagacacg acacgattcg gtgaatttat cgaattgcat tatgtacgaa
     9421 agtagaagta aataaaataa aaaaggcaac tatatgcaga aatgtcctgt acatagttgc
     9481 cttttttatt accgttatgc tttttactct gttaatttgt tagaaaaatc tagatacgca
     9541 tctaaaatcg tttggaagaa acttaatgtt ccttcaacga tattaccatt ttcatcaatt
     9601 agattcgcaa cgtttccgat atatgcttcc ggttgctgca aggttggcac attcaaaaag
     9661 acaagtgatt ggcgtagatg gtggtttgcg ccaaagccgc cgatcccacc tggtgatgca
     9721 gtaacgacta aacctggttt atgatcccaa acactgtgtc cataaggtct tgagcctaca
     9781 tctaaagcat ttttcaatac tgctggcaca gaacggttgt attcaggagt aacgaaaacg
     9841 acaccgtcta gtcccctcac ttcctcacga aaacgagtcc attcagcagg agcctgttct
     9901 ggagtttcga gatcctcatt gtaaaatggc agatcatcga tttttacaaa tacactttcg
     9961 tacccttcag gaagcaattt cgcaaaagct tctgctactt ttttgttgta agaatctttt
    10021 cttaaactac caataaaaaa tccaattttt tttgtcatac gatttttc
//
LOCUS       DACGEU010000094        10051 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.096, whole genome shotgun sequence.
ACCESSION   DACGEU010000094 DACGEU010000000
VERSION     DACGEU010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10051)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10051)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10051
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.096"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            <1..96
                     /locus_tag="IXR40_002356"
     CDS             <1..96
                     /locus_tag="IXR40_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAQ4362160.1"
                     /translation="RNNIPRKSLDYRTPLEVFLSYVSIDDLSNLI"
     gene            361..840
                     /locus_tag="IXR40_002357"
     CDS             361..840
                     /locus_tag="IXR40_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362161.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNMDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
     gene            873..3101
                     /locus_tag="IXR40_002358"
     CDS             873..3101
                     /locus_tag="IXR40_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA domain-containing protein"
                     /protein_id="HAQ4362162.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKERTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            3230..4873
                     /locus_tag="IXR40_002359"
     CDS             3230..4873
                     /locus_tag="IXR40_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HAQ4362163.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKHALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(4946..5491)
                     /locus_tag="IXR40_002360"
     CDS             complement(4946..5491)
                     /locus_tag="IXR40_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HAQ4362164.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(5514..5999)
                     /locus_tag="IXR40_002361"
     CDS             complement(5514..5999)
                     /locus_tag="IXR40_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAQ4362165.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            complement(5989..6801)
                     /locus_tag="IXR40_002362"
     CDS             complement(5989..6801)
                     /locus_tag="IXR40_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HAQ4362166.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            complement(6940..8472)
                     /locus_tag="IXR40_002363"
     CDS             complement(6940..8472)
                     /locus_tag="IXR40_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HAQ4362167.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQIPILYLMEQPALSVSQSFLD
                     KNEISYMTHTSGTTGIPKLICHSAHSMGWRTKWQKTVFTKISEKKLIAFHISPVHSRF
                     NIGISSLMSMGFPMMPLANAQSSKVVHMLEAHRPIALETHPNNFVQWRFTAKEHPEAF
                     SGIRYYHSTFDAINNQTMKTFLRTSMAQDAVFLQVYGQSECGPMILKAHTLESLKTSD
                     ARDMGVGLEDMTSARITDSVGNVLPENTDGHIQLLSKGRALTYYKEDARFQENVYGDW
                     WDSGDYGFMDKHGHLFLKDRQVDLIETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSP
                     QPIIALAPDKEMDWNRWWEQVHELPRLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQ
                     KS"
     gene            complement(8581..9612)
                     /locus_tag="IXR40_002364"
     CDS             complement(8581..9612)
                     /locus_tag="IXR40_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAQ4362168.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
BASE COUNT         3352 a         1856 c         1932 g         2911 t
ORIGIN      
        1 cgaaataata ttcctagaaa atcactggat tatcgaacac ctttggaagt atttttgagt
       61 tacgtaagta ttgatgatct gtctaactta atttgacaat taagaataca aaaaagatgt
      121 tggtgaagtt caccaacatc aaaaagtata gagccaaaat attccaacat catcttggac
      181 tttctacatg ttactaatga gcgtgtaaaa gaacgagatg gtgtttttat ttctatcaat
      241 gaagctcttt ttctttgcaa tcctcacttc aatcctctat aatgtcgcat atagtttagt
      301 aaatgagtaa actactaatt tacttattta ctaaaaataa aaggatgagg agttaaaata
      361 atggaaatac caacaaattt aaaacataaa ccagtaatcg ttgtagaaga ctatgataaa
      421 gttgatggaa gaaatgcatt aaatatggat gcaaaagggc tttcactggg ccttgctcag
      481 tggaatgatc gtggaaaagt cgatatctca ggcaaggtat ggcgacatac tggagaaaaa
      541 tggtcacgac agtcggaaga attaccaatc acacgtattt tagatttagc gatcttagct
      601 gcgcaaggaa gtttatactt ccaagatgct tatcgttatg aaaaatttta tgatccagaa
      661 aatccagtcg tagacatcat tggattacaa gggaaccgaa tgacggtaga agtagatacc
      721 aaaaatccaa agatcgatga agacatcatt ttgtattacg atacactaca aaaagacgga
      781 gaactgattg gggaacgatt ccgtatttta aaacgtcttt tagatgagct aggatattaa
      841 tagacagaga tgatcaaaag gggaagagaa gcatggagaa tttctcacta acagaaaacc
      901 gaaccttttc acggctagaa aagcaaatga tctggaagaa accgaaaagc catcggacaa
      961 gtgcagaaga atggcggatc gcctccgaaa tcaaagggaa ttggcaagat cctgaaatga
     1021 aaatcagtaa cgtacttttg gaaggagatg ccgggtcggg gaagacacaa ttagccaaag
     1081 cactatctgc tgatctgcaa cttccctata caaaagtgac ctgttttgca gatatggaca
     1141 aatcagatgt tttcggagcc ttattacctg tagtagattc taataaggaa caagaccaag
     1201 aattactaga agctatttac caaacagata cacttgaagc tgtactgaca ctgatccaga
     1261 accattacgg cattgatcct ttttctgcta aagaaaaatt agcagagcta gttcaaagga
     1321 tcgaagctga ttatccagat gcaatccatt acagctatta cccttctgaa atcgttcgag
     1381 cgattgaaaa aggctattta ttagagattc aagagccgac tgtcatccga gatgcctctg
     1441 ttcttgtggc acttaactca gcgctcgaac caaatgggat gttgaattta ccgacaggaa
     1501 tcattcgtcg ccatccagat tgcgtcattg tgatcactac aaatcgaaat taccaaggaa
     1561 atcgcccatt aaatgaatct ttaagagatc ggatgcaaca tgcggaaaaa atggatcttc
     1621 ctgccttaga agtcatggca gaacgtgcga tggcgaaaac tatgatccaa aaacaagaac
     1681 ttctcttaaa gatggcagag attatccgtt tgttggatga aactgcaaaa gctaacgcca
     1741 tcaaaggtgt agcaggaatg cgttcttatt tttattgggc aaatacctat aagcaaggac
     1801 aagatttact ccagtcgatt tatccaaaag ttttgtataa attatccact gattcagatg
     1861 aattggcaat tcttgaacaa gctttgtctg acagtggatt gctactggaa cttcaggaca
     1921 tattgagaaa agaaaaatgg ggtcatcctc aatctgagca tacaaaagaa agaaccatta
     1981 gcgccgaaga agcaaatgaa cgaaacatca ctgaaaatgc tgaagaaatt ctgcgcttag
     2041 atgaaaagaa atcgttgtct gctgaagaac caaatgaggg agaagagaaa caagaagaaa
     2101 caatagaaaa aaacgagatt cctcctcaaa tgcaaaaaga acgcagtagc gatatcgaag
     2161 gaaaaaatca aaaagaacaa caaacaggag atgattctca agaaatgtct gcttctgaca
     2221 tggaagcaca tgataaggaa atcaagaagc aactgaataa agaagcgcga caaatcatga
     2281 aggaaacgat tcatgaaaaa gaaggtctca tcgttcaccg accagctttc caaggaaaaa
     2341 cgccggaagc acgtgagcta cacatgcaag taatgccaat agtagaatca cttagccggc
     2401 aaattttaga gttactggat aatgaacaaa cagagacgta ccaaaaagga aaatacgaag
     2461 gtcagcggtt caatgcaagc aaagtagcat atggtgattt gagaaatttt gacaaaaaga
     2521 acccgccaca tgagcaacct tctttagcgg tagctgtacg gatcgatgaa tctgggtcaa
     2581 tgatacggga tgatcggatc gaagcggcaa aaaaagcagc gattgccatt gccgaatttt
     2641 ctaagaaagt cgatatccca ttgttgattt acggagatac agcagaccgt tcgtcaagag
     2701 aaaagacttc tttgttttct tataaagaat ttgaagacgg atttcaatgg ttaaatgaaa
     2761 aattagtcac tatgaaacca aggcaaaaca atcgtgatgg tgctgcactt cgtttagcag
     2821 cagaaaaatt aaacagacaa tccgcaacaa ccaaactgtt gcttaatatt agtgacggtc
     2881 agccaaaagc gttgccggat tatacaggca aaaaagcaaa agaagatatc cagtctgttt
     2941 tgaaagaata tgaacgtcaa ggaatcctat ttgtctccgc agctattggc caagacaaag
     3001 aagaaatcaa gtcgatctac ggtgaaagtc gttttgtaga tattactgac ttgaatgaat
     3061 ttcccaagca aatgattcaa ctgattgccc gctatctatg ataaaataaa gctcaacgaa
     3121 cgcacttagc agattcgttg agcttttcgt ttctagttac cggtaacaag gatacttcta
     3181 aaatagaatc ggttataatc aagagggacc gttaaaggag tgaaacgata tgatacaaga
     3241 acaaaaatgg tggaaagaag cagtaggcta tcaaatctat cctgctagtt tcaaagatag
     3301 caatggcgat ggtcaaggag acatcaatgg gatccgtgaa aaacttaatt atttgaaaga
     3361 tcttggtatc ggctttatct ggatcaatcc gatctatcaa tctccatttg tcgataatgg
     3421 ttatgacgta agtgactatc aagatataga agagagattc ggaacgatgg aagattttga
     3481 tttattgcta aaagaagcac atgaattagg gatcaaagtg attatggatc ttgtcatcaa
     3541 ccatagttcg gatcagcatc aatggtttga agaatcgaaa aaatctaaag aaagcccgta
     3601 tcgcgattat tacatttggg tcgacggggt agatggcaaa gaaccgaata attggacatc
     3661 gattttcggc ggttctgctt gggagtattc tcatgaaact ggacagtatt atctgcatgt
     3721 ttttgcaaaa gaacaaccag acttaaattg ggaaagcgag aaattgaaag aagaactatt
     3781 caatatgatc cgatggtggt tggataaagg gatagatgga tttcgtttag atgcgatttc
     3841 tcatgtaaaa aaagatgaat attcagtaaa agccacagag aaccctttct caccctttca
     3901 aaatgtctca ggaatcgaag aacatttgac cgatttgaaa catgtttttg aagagtacga
     3961 tatcatgact gtcggagaag caagtggtgt cactgcagaa gaaggaccac aatgggtagg
     4021 gaaagacggt tatttcgata tgatattcga atttgatcat atccatatct ggcagcaaga
     4081 aaaagaaggg caattagatg tccttaaatt gaaacatgca ttaagcgctt ggcaaacttc
     4141 attggatggt atcggatgga acgctttata tatggaaaac catgatgttc ctcgtgccgt
     4201 ttcagtgttt ggagatactc gtcccgattt ttgggctatg tctgcaaaag caatcgctat
     4261 gatgtatttc tttttgcaag gtacgccatt tatttatcaa ggacaggaaa tcggaatgac
     4321 gaatatgccc tttgaatcga tcgatcaagt tgatgcagta gattcgaaaa gactttataa
     4381 aaggctgctt gcggaaggta agacaagaga agaagcattg gatatcattc gtgaaacaac
     4441 gagagacaac agcaggacac ccatgcaatg gacttcggaa caatatgctg gtttttctac
     4501 acatgaacct tggctgatca ctaatccaaa taccaaaacg atcaatgtag aacaacaaga
     4561 atatgaacca gagtcggtcc tgcaattcta taagaacatg atccgcatta gacaaaccaa
     4621 taaaggtctg atatacggtt cttataaaga atatcttcat gaacatccac aactttatgt
     4681 ctatgaaaga tatttagaag atgaacaata tcttattatg gtaaacttaa cagaatcact
     4741 tgctgactat gaacttccaa aagaagcaga tcagtcctgg acattactct tgtcaaattc
     4801 ctctagcgga gaatttgaag ctaaaggcat actagcacct tatgaagctc ggttatataa
     4861 aacaaacaag taaaacttcc tcgttaaagt tcattagttg gactttgcga ggaagttttt
     4921 cagattgctc tgtcaattac tcatttcaat aattcgctct aggaccaccg atatatttag
     4981 gacgagagcg aagggctgtc acgtgagctt gtccaagggt tttcaaacga ggtctgacag
     5041 gtacttggac atgcttgata tgcataccga ttgatgtgtc accgatatcg ataccggctt
     5101 gtccaactac gtgttccact tcgacaggat cattgaactg gtcaaaagca gcaacagaac
     5161 aagcacctcc agcatgtagt gcaggaacaa cagagacaat ttcgaaattt tttgcttctg
     5221 ccactgttcg ttctactact aatgctcggt tcaaatgttc acaaccttgg acagctagcg
     5281 caatttcttt aggatccaac aactctttta acgtacggat gatccattga ccaacttccg
     5341 cactggaatt ttttccaata tgtcctccaa cgacttcgct tgtgctgcat cctaaaacaa
     5401 aaagatcacc ttttttcaag tgtgcctcag ccaatatgtc attaactatt tcagtcaatt
     5461 ggtcttttaa ttctttttct gacaacttca ttttctaaaa ccttcttttt caattaatat
     5521 tgcttccgtg cttgaatacg ttgaagactt gcagttatag gaaaggcaag tcccattcca
     5581 atcagatttt ggaagatgtt tcctggtata gaagccactc cagccggcca atcatataaa
     5641 atccaaccgg cgataccata gccgatgatc ataactaagc ttcctaataa aagccctaat
     5701 ccccacatac gagtagaaga tttgctgaaa gaaccagcaa catatccttg taacccgtgg
     5761 atcactaatg aaaaaactgc ccactgcgga tatcctgaaa tcaaatcgat caatagacca
     5821 ctggaagcac caacaactaa tccacccgtt ggaccataaa gaaaagcagc ggtatagatc
     5881 ccggcctcgc ataatgtcac aaatccattc gtagccggta cagggatcaa aattgttaat
     5941 gaaagggcaa ctgtcaacgc aatcagcata gcatagatcg ttaattgctt agttttcatt
     6001 tctcattcct cctttttgaa taccgccaga ccagacactt ccggtatgat cgttcatcag
     6061 cacgccatta gaaatacaat gggcaacaaa ttttttactt tctgctactg ctttggtaaa
     6121 atctgcccct aacacaagat tcgctgttat tgcagaagaa aaggcacaac cggccccgtt
     6181 tactgttgta gtgtcgattt ttttatgaga aaatacctca taatgatcaa ttgaatagag
     6241 aagatccaca gcttcatctc cagccatcct tgtgccgcct ttgatcacaa tgttttttgt
     6301 tcctgaagca gtgagttctt tagcgagatg gatcatttct gttaacgaag agggaagagc
     6361 ttgaccagaa agtaaagcag cttctgccaa attaggcgta atcatcgtaa caagtggaaa
     6421 aagttcttcg atgagctgcg aaatatacaa ttgattgatc acagcttcag tttctttgaa
     6481 tgccaaaaca gggtctaaaa tgattgggat attttgtttt gtttttatga agtctcgaac
     6541 aaccatgatt gcttcacttg aattcaataa cccaattttg ataccatcta atgaagtcat
     6601 tttatcaatc gaaactaact gtcgtttaag caattccaaa gatatagatt ccagcataaa
     6661 tcgctcatta atatctagtg cccctataga agtcaaggcg cttagtccga atagaccaaa
     6721 attctcaaaa gtttttaaat ctgtttggat tcctccacca gcaaatggat cagaaccgcc
     6781 aattgtcaag attcttttca taacattttc ctccatgaat aagagtataa cgaaattttc
     6841 aaaaaagaaa aacagccaat tggcatattt ttatctcatc caatttaaaa aaacaaaaag
     6901 aaaagaaaga ccaaaatgga tctttctttc cttaaatagt taggactttt gtgattttaa
     6961 ttctttctcg atttgaagcc gttgcacttt cattgtagct gttcgcggga ttgcatcaaa
     7021 atcacggatg atagggacgt tcaagcgagg aagttcatgg acttgctccc accatcgatt
     7081 ccaatccatt tctttatcag gagctaaagc aataatcggt tgtggagaat gatttttatc
     7141 ccttacaatc actacttctg ccaaaaaatc taacgaatct aataaaaagt cttcaatagc
     7201 taatgtacta ttgatcgttt cgatcaaatc cacttgccga tctttcaaaa ataggtggcc
     7261 atgcttatcc ataaaaccgt aatctccgct atcccaccaa tcgccataaa cattttcctg
     7321 gaaccgtgca tcttccttgt aataagtcaa agcccgtcct ttagacagta attgtatatg
     7381 accatctgtg ttttcaggta ggacattccc aactgaatct gtaatccgag cgcttgtcat
     7441 gtcttccagt ccaacgccca tatctcttgc atcacttgtt ttcaaactct ctagtgtatg
     7501 agccttaaga atcattggtc cgcattcact ttggccatat acttgaagaa ataccgcatc
     7561 ctgtgccatc gacgttcgca aaaatgtctt cattgtctgg ttgtttatag catcaaaagt
     7621 ggagtgatag tatcggatac ccgaaaaagc ttctggatgc tccttagcag taaaacgcca
     7681 ctgaacaaag ttattcggat gggtctctag tgcaattggc cggtgagctt ccaacatatg
     7741 aacaactttt gaactttgtg cgtttgctaa aggcatcata ggaaatccca tggacatcaa
     7801 agaagagata ccaatattga atctggaatg cactggagag atgtgaaaag cgattaattt
     7861 cttttccgaa atttttgtga aaactgtttt ttgccatttc gtccgccatc ccatagaatg
     7921 agcagaatga caaataagtt tagggatacc agttgtacca gaagtatggg tcatataaga
     7981 aatttcattt ttgtctaaaa atgattgaga aacagacaaa gcaggttgtt ccattaaata
     8041 aagaatagga atctgttttg attttgttcc atttgaaatt tctctcactc gcttttttgt
     8101 ctcatcatca aataaaatga aagggtcttc taaacgatcg ataaatactt ccattgttgt
     8161 tgttggtaga tgataagaag tcatgacagg cactgcacca aggtaagaca cagaaacagc
     8221 tagaaggtat gtgtcaaaag cggaactctt ataaataata actttgtctc cggatttcac
     8281 tccaagatga gccaattgat aagcccgttt caacacactt tcgcagcatt ttttgtaagt
     8341 tgtttcaagt cctaattctg ggaaagctga aagtggctca tcaaagataa tcggggtctc
     8401 ggaaaagtta gctgcagctt cttgaaaatt cgtaaataag ttcaaagggg aatacgttat
     8461 ggtctccatc attcacactc cattatcttt tgttaagtaa tatacaaatt caagataatc
     8521 gtaacataat cctttatata ataacatagt ttattgtgaa aaaaagatca tacatttgtt
     8581 ttatatggaa gaaacccgaa cgaatgccgc taattcgtga taagaaaaat caaccatctt
     8641 ttcccagata tcttgaaaag aatgggatga gaggtatcga ttaccacata aataatttac
     8701 cgcgtcagca tcatctaaat atagttctgc ataataacga tatgtttttc tgcatagttc
     8761 tggcgatacg tttttatata ctgtaatttt gctcaaaatt tggcgaatag tccgaggaga
     8821 aatttgctga tcatgtgagg aacgaaaaac aaaagaattt tcgtccgtat tttgtgctgt
     8881 taacttaaaa tagttctcca gaaatggcat cgcttctttt ggtattggta ctttattcag
     8941 tctgttttct tttctattca gattaagaat ctgcttggtc aaagatacat ctttacgttt
     9001 aagttctact acttcatgga tctttaatcc gcaatacaga agaatggcag taattgcaag
     9061 gttcctcggt ctattctttt cttcaaagct agcttctctg cttgtttgaa agccttcaat
     9121 cgggataaac aaatgctcaa aatctttgaa aagttctgca tcgatatatc gcggagctgc
     9181 tttggttgtt tccggtaaac ttgtacccaa aagagaaatc tcttcttcaa tcagtccttt
     9241 ttgatacaaa aatcgtaaaa aatgatttaa tgaatattgc ttccttgaaa tcccgtaata
     9301 gctattttca aacaattgct ccgtttcttg gttcgctgta gtttggaacg aacgagtatg
     9361 tcgatagatt ttagctaaga aattctgata atcttgtttt tctaaatgga taatcagctg
     9421 atcatccact tcttcagaaa atacttttct caaataatca gtaaacagat gaaaatcttt
     9481 tgcgtattca tagcgactgc ctaatgaaag ggaagaacga ttttcttcta aaaactgttg
     9541 aaagacggaa gggagcaagt gtgtacgttg ctttaacttt tcttgcagtt gttttctagt
     9601 tttgctgtcc attacaaatt ccctccaata gtgttcattt tctatatttt accgcatttc
     9661 atcaaatgaa gatagacagt ttgtcttgat cttaggaagc aaatttttaa ctaagtacta
     9721 gctaaaagat atgaagtaag aagatacatt tttagttatt ttattagtgc agtcattctt
     9781 ttgatctttt aattgattta tcctcttttt agctatgtgg ttacttcatg agcaatgaaa
     9841 tggatttggt tcgttctaat ggcaggaggc tctttctttt atttccgaaa aattagaaaa
     9901 cattttttca gaatcgattg gctctccatt tattcaataa tggtttgtct aacgatattg
     9961 ttgggataat tcttaaagaa gtattagaaa tagttggtac ttcattactt tacatgaaga
    10021 tttattctat ggtaggagca attatattga g
//
LOCUS       DACGEU010000095         9988 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.097, whole genome shotgun sequence.
ACCESSION   DACGEU010000095 DACGEU010000000
VERSION     DACGEU010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9988)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9988)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9988
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.097"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(203..1654)
                     /gene="cls"
                     /locus_tag="IXR40_002365"
     CDS             complement(203..1654)
                     /gene="cls"
                     /locus_tag="IXR40_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HAQ4362169.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            1995..4661
                     /locus_tag="IXR40_002366"
     CDS             1995..4661
                     /locus_tag="IXR40_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAQ4362170.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNK
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            5025..5777
                     /locus_tag="IXR40_002367"
     CDS             5025..5777
                     /locus_tag="IXR40_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAQ4362171.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(5799..6953)
                     /locus_tag="IXR40_002368"
     CDS             complement(5799..6953)
                     /locus_tag="IXR40_002368"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HAQ4362172.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYSLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            7138..9579
                     /locus_tag="IXR40_002369"
     CDS             7138..9579
                     /locus_tag="IXR40_002369"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HAQ4362173.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKQYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     NVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
     gene            complement(9736..>9988)
                     /locus_tag="IXR40_002370"
     CDS             complement(9736..>9988)
                     /locus_tag="IXR40_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAQ4362174.1"
                     /translation="TEGFQETLKTISSTLPQSFKKKFTIFHRYQSGISNAFKVPHSNG
                     VTEGLNNKIKLIKRIAFGYRNFYNFRARIYLQQGLIFEN"
BASE COUNT         3203 a         1799 c         2144 g         2842 t
ORIGIN      
        1 gaaagaggtc gtgagcctgc cgtccagctc cgagtcacaa ggaacaagtt caaaaaacag
       61 cttctcatgt ttgttgaata ttgtgacttg tgaccgagga gttggcagga gaacaccgtt
      121 tgttcggaag aagggactgt gacaagattt ttgtcacagt ccctttaatc ttagtatatt
      181 tttctctact tgaataaaaa aattatagga ttggagaaaa taatcgagaa atttgttgct
      241 tgaataatag ccagttagac atttccttga ctgtttcagt tgtcatggat gaacaatgtg
      301 tctcatcttc tttgaactga gtagcaagtt cttctaaaaa ctcaggatcg taaatgacag
      361 cacttgtttc aaaattcaat cggtagctac gaatatcttg atttgctgaa cctaccatgc
      421 agatttcatc atccattatc aatgtttttg catggaggaa gccgttctca tagacaagga
      481 tttgtacatt ttccttgatc agctgccgag cataatattg tgttgctcga taaataaaag
      541 gatgatccgg tttgttggga atcatgattt tcacatctac accagaggca gttgcgattt
      601 ttaaagcagc aatgacactt tcatcaggaa caaggtaagg tgtctgtatc caaacacgtt
      661 ttttagcaga agtaatcaat ttgataaatg aaagcttgat ttgttccctt tcgttattcg
      721 gtccgcttga aacaagctgg atggatgtat cagcaagctt agattcatct cgatctgctt
      781 ttttaaagaa ataattcaaa tgatagccga cctttttttc ttcaggtacc gagacgttcc
      841 agtctgttaa gaagcgaagc tggagcaaag aagaagcggc accgaaaatc cgtatatgcg
      901 tatcgcgcca atagccgaat ttttttgttg tatttacata ttgattggca atattgaaac
      961 caccggtata actaatcttt ccatcgatca caacgatttt tcggtgatca tggtaattca
     1021 atcggaaacg aagtaatgcc ctttgtgagg taacaaatgt atggacatgt ccaccatttt
     1081 tgattagacg attgaaatct tttgcttttg tgccatgaga gccaaatgca tcatataata
     1141 ttcgaacttc cacgccttct gcggcttttt cttctaaaac atgtaagact tgctggccga
     1201 tattatctgt cacaaatgcg taatattcga tatggatcga atgtttggct ttttttagat
     1261 cttgaagcag tgaatccaat ttctcttgtc cgtctgtgag aagagtgaca gaattcattc
     1321 ttgtcagcgg catacgattt aatgaagaga agaagtcaac aaattgctgt ttgtctttat
     1381 cgcccatgtc aggatcgtaa tgttcaatgg tatctcctct aaaagactga aagttttcta
     1441 attctttcaa gtcactttgt cggagataga attttttctt atccgttaat ccacgtccga
     1501 aaaataaata taatacaaag cccaccccag gaagggcaaa caatactaag agccatgccc
     1561 aaatggctgc tacatctcgg ggtttgatca aaatagccac caaagcaata agtgcattta
     1621 atagataaag ggcggttata atactagata ccacaaaaat gttcctcctt acatacaata
     1681 acattagtat agcatgatag aagaaagaag cctaccaagg tgaatatact tttcactcct
     1741 ttcatgaaaa tgtaggtaaa tcgggctaaa gtagttgctt tttgtaggtt aataaggtag
     1801 gatattagta cagttgaata tctccttagg ggagtaaccg gcaacgtttg ttgcgataat
     1861 atcaacagta agttaaccaa atggttttct ggtattgtat gaaatggtga gacctaagac
     1921 aaatgcgtat ttgtcttagg tctctttttt ttcagacagg actagggcca agatcaaaaa
     1981 atgggggatg aaatttggaa aacaaggaac aagcacaaca agcggtctat aaagaaacga
     2041 tcgactcgtt gatgcagcaa acgcagagct caaccgatgg attgagcacc acgcaagcga
     2101 aggaaaaatt agaaagagat ggcttgaacc agctaaaaga aaagccgaag aagccaactt
     2161 ggaaattgtt cttagaaact ttcaaagatg caatggttat cgtattgctg attgtcgcac
     2221 tgattcagat ggtcatgggt gactacatcg aattcttagt tatttttgca gtattgatgt
     2281 tgaattctat aatcagtgtt gtccaaacaa aaaaagcaga aggttcttta gaagcgttga
     2341 aaaacctttc agcgcccgat gctcgagtga ttcgtgatgg taaggaaaaa acgattccgg
     2401 caaacgaact tgtggtagga gatatcgtgt tgttagacgc aggcgattat gtacctgctg
     2461 atggacgttt actagatgcg ggatcattaa aagtagatga aggtatgctg acaggagagt
     2521 cgacttctgc agaaaaagaa gtaacggata tcacaagtac ggtaccaatc ggagatcgta
     2581 caaatatggt attcagtgga acgatcgtaa cttacggacg cggtaaattc ttagtgactt
     2641 caactgggaa taatacggag atcggacaag ttgctggcct tttggaatca acaactgagc
     2701 aagtcactcc gttacaacga ggtctggata aattcagtaa aaaactaagt ttggctattt
     2761 tggcattgtc tttattgatt ttaggtatcc aactgtttcg tatttatctt ggagaaggta
     2821 caggagatat gactgcagat atcgtcagcg cagtgatgtt tgccgtagcc gtagccgtag
     2881 ctgctattcc agaagcatta cagtctatcg taacaatcgt gttatctttg ggaacgaata
     2941 aaatggcaaa acgtcatgcc attattcgga agcttccagc agttgaaaca cttggttcga
     3001 caagtatcat ctgtacagat aagactggta cattgacaca aaacaaaatg acagttgttg
     3061 actacttttt aggtaatggc gatactgggg atttcacaaa tgacccttca aaatggacag
     3121 ctgacgaacg tcgcttgatc gaaatcagtg ttttagcgaa tgatgcatcg atcagtgaag
     3181 acggtactaa attgggcgac cctacggaag tagcgtttat cgactttagt gaaaaattaa
     3241 accagcctta tcaggaaatc cgaaacaact acccaagaca agcagaactt ccttttgact
     3301 cagatcgaaa attaatgtct actggacaca caattgataa caaaaattac ttgtttgtta
     3361 aaggcggacc agatatcgtc ttccaacgca gtaaaaaagt attgctaaat ggtgaagtcg
     3421 ttccgatgac ggatgaattg atgaaaaaat tccaagagca aaatgaagct ttttcaacac
     3481 gcgcattacg tgtactagct tttgcttacc gtccacttga taattttgat ttatcatttg
     3541 aagatgaaga cgatttgatc cttgttggtt tgcttgctat gatcgatcct ccacgtgctg
     3601 aagtgactca ggcggtaaca gaagcaagaa gtgcaggaat caaaacaatc atgattactg
     3661 gtgaccacaa aacaacagct gttgctatcg caaaacaaat cgggattttt gaagaaggaa
     3721 acctggcttt gaccgggacg gaactagatg aattgacaga agatcaacta aacgaagttt
     3781 tagaaaaagt cactgtttat gcacgtgttt cacctgagaa taaaattcgt atcgttcgtg
     3841 cttggcaaaa taaaggtcat atctcagcta tgacaggtga tggtgtaaat gacgcaccag
     3901 cattgaaaca agcagacatc ggaattgcta tgggaacggg tacagatgtg gcaaaagatg
     3961 cagcagcgat ggtattgacg gatgataact ttgcttctat tgtcagcgca gtagaagtag
     4021 gacgtaatgt gtttgataat atcaagaaag ctatttctta tctatttgca ggaaatttag
     4081 gtgcgatcat tgcgatcatc tttgccttag ttgctgactg gtccaatcca tttacagcat
     4141 tacaactgtt gttcatcaat ttagtcaatg attcactgcc agcaattgca ttaggtacag
     4201 aaaaagctga acctgctacg atgaaccgcc cgccaagaga tccaaattca ggaatcttta
     4261 cggacaaaac attgatttct gtaacgtatc gtggtgtgct gattgggatt gctgttatct
     4321 ttgctcaatg gcttggcatg cagcattcac ctgaattcgg tgtagccatg tcattttcaa
     4381 cattgatttg gtgtcggaca ttgcaaacat tcccagcacg ttcaaacaca caaacagcta
     4441 tccaagcagg gttcttctct aacagaagtg tcttactagc tgtagttgta tgtagcgcgc
     4501 tttactgctt aacaatgatc ccaggactga aagaagtctt ctctatccca tcagcatttg
     4561 gattgacaga agtctttaca tgtatgggaa tcgcacttgt gacaattgtt ttgatggaaa
     4621 tcactaaatt gatcattgta cgagtacaag gaaataaata aaacgaatca acgaggttgt
     4681 gagcctgccg tttaattctg agtcacaagg tgcaatttca acaaacagct tctcatgttt
     4741 gttgaatatt gtgacttgtg accgaagagt tggcaggaga acaccgttta aggaagaagt
     4801 tgtaaaatca gcattttgag ctaatactga gggtcatctg attggacact gtttattcgg
     4861 aaagagggac tttgacacga ctttggtcac agtccctttt tttatttatg atagacggaa
     4921 agccaatcat tttattattc atcaaaagag atagaataga taaaagagga gaatgattta
     4981 ttccgaaaag tgaaaacata taacaaaaaa ttagaggaaa tcaaatgaat gaaaaagaat
     5041 gggatgaatt tgctgaagaa tattatgaaa tccagcaaga atcgcaagta actattgctg
     5101 aagatgtaaa aaattatctg aaaacggaga aagtcctgcc tgctgaaaca gcagcagacg
     5161 ttgctggagg atctggcaga tttctttcct tagcaaaaga aattaatcgc tatgatttga
     5221 tcgatttttc ttcaggaatg ctagaaaatg caaaaaaaga agcagaaaaa aatgagttgc
     5281 caaatgtttc ctttatcaaa cagtcgttag aagaatttat ccaatcaaat gagacatatg
     5341 aaatggtttt tacagcagca aatccagcat tggtacatct tattcaatta gaaaaattga
     5401 tgaaaaagtc aagcaaatgg tgcgtgataa tcagagtagt ggaatcaatc gatgatgttt
     5461 tttatcctat cgaaaagcaa ctaggaatga tagaagaaga tcctaataca tcgccagttg
     5521 taatggatca atttgaaaca tacttaattg atgaaggatt caaagtgaag aaaaaagatt
     5581 ttacttattt tacacaggaa tcaattactg aagaattgat gaagctatac tatgacgcgt
     5641 acgcaaaaga tcctgttgtg accaggtaca ttcgcaaact attcagtgaa aaacgagaaa
     5701 tccttagtac gactaagctg acctatagac tgctcctttg gtccgcagat aaaaaaagaa
     5761 cctttcacga ctcgtgaagg gttcttttta tgattttatt atattttgta gtaacgaata
     5821 tcattttcga tctttgtaat cgaaaaaggt acatctgaag tatattctgc acattctccg
     5881 tgttcaggaa gcgtctcact gaaaatcgtt tcatattcgt caacagtgat ccgtgttcga
     5941 gaatctagca tctcttgatg agattgtgcg aagagatatt cttgatagtt ttcttccaga
     6001 taacctgtaa aaaattcact tactgcacca gaaccgtagc tgaatagacc gatgcgatct
     6061 cctggctgta gtgatttcga attttccagt agagaagtta gccccaggta taatgaacca
     6121 gtgtaaagat taccgattcg tcggctgtaa cggatgcttt cttcatagcg agccataaga
     6181 cgttcctgat tttcttcgtc tgtttggtct aatacgcttt gcaatgcctt ttttcccatc
     6241 ttagtatacg gaatatggaa agcaatcgcc tgataatctt cgagtcctcg acccgacaat
     6301 tctttatgtc gattccaaac tttttggaat gattcgatat acgtagaatt agataaagga
     6361 ccatcaacaa caggaaattc gctataatct ggacgccaga aatcatagat atcttctgtc
     6421 agaaatacgc tgtcgtcttc aatcgataaa atacgcgggt tttgagtgat catcatcgca
     6481 acagcaccga caccttgcgt cacttcacca ccgcttgcca agctgtaacg agcaatatca
     6541 cttgctatga ctagtacttt tcgttctgga tgatttttga catattcttt cgccatgtgc
     6601 aaagctgcgg tgccaccgta gcaagcctct tttacttcaa aagaacgagc aaaagattgg
     6661 attttcagta aatggtggat aattaccgca ctcgcttttg aatgatcaat cccggattct
     6721 gttccgacga tgaccatgtc gattagctca cggtcttttt ctgttacgat tttgctggca
     6781 gcatttgctc ctagtgtaat gatgtcttca tttgcacgat tgactgccat ttggtcttga
     6841 ccaatcccta tatggtattt tgcaggatca tccccacggc tttctgccaa ctctgtcata
     6901 tctaaatata aattaggaat aaaaaaggaa agacgatcaa tccctatttt catttcaaca
     6961 cctctttact tatgataaaa aacttacttt actaaggtat cataaaaaga ttaaaagaaa
     7021 tataaaaaag agaatattta aggattgtta aaatttaatc ttagaaaaaa ataactggaa
     7081 caagagctat ttgtttttac agcaaagaat ggtatatttt tgtaggaggt ggcttacttg
     7141 aaagaagtcg ttatgataga tgctgcaaga acgccgatag gaaagtatcg cggaagttta
     7201 agtccattta ctgcagttga attaggcaca cttgtgacta aaggattatt agataaaaca
     7261 aaactgaaaa aagataaaat cgatcaagta atatttggaa atgtcctgca agctggtaat
     7321 ggtcaaaatg ttgccagaca gattgctttg aacagcggtc tccctgtaga tgtcccagca
     7381 atgacgatca atgaagtttg cggatctggt atgaaagcag tgatcttagc acgccagctg
     7441 atccaattag gtgaagcaga acttgtgata gccggcggaa cagagagtat gtctcaagca
     7501 cctatgctga aacagtatca gtcagaaaca aatgaatatg gtgaaccaat ttccagtatg
     7561 gtcaacgacg gattgactga cgcattttca aatgcacata tgggattaac cgcagagaat
     7621 gttgcaacac aattttctgt gagcagagaa gagcaggatc gctatgcctt gtcgtcccag
     7681 ttgaaagcag cacatgctgt cgaagccggt gtattttctg aggagatcat cccagtcaag
     7741 atttctgatg aagacgtgtt atctgaggat gaagcagttc gtggaaatag tacattggaa
     7801 aaactgggca cgttacgtac agtattctca gaagaaggaa ctgtaacagc aggaaatgct
     7861 tccccgttga atgacggtgc ctctgtggtg atccttgcat ccaaagaata cgcagaaaat
     7921 aataatctgc cttatttagc aaccatcaaa gaagtagcgg aggtcggtat tgacccaagt
     7981 atcatgggaa tcgctccaat caaagccatt caaaaattga cagatagatc aggaatgaat
     8041 ttatcaacaa tcgatctttt tgagatcaat gaagcatttg cagcttcttc tatcgtagtt
     8101 agccaagaac tgcagttaga tgaagaaaag gtcaatatat atggaggagc aatcgcatta
     8161 ggccatccaa ttggtgcaag cggtgcacgt atcttgacta cattagctta cggattgctt
     8221 cgtgaacaga agagatacgg tattgcttca ttatgtattg gtggaggttt aggcttggca
     8281 gtcttgttag aagcgaatat ggagcaaaca cataaggatg tgcaaaaaaa aaagttttat
     8341 cagcttacgc catctgaacg gcgcagtcaa ttaatagaaa aaaatgtatt gacacaagaa
     8401 actgcgttga tttttcagga acaaacactt tctgaagagc tctccgatca catgatcgaa
     8461 aaccaagtga gtgaagtgga aatcccaatg gggatcgcgc agaattttca aatcaatggc
     8521 aagaaaaaat ggattccgat ggcaacagag gaaccatctg tcattgcagc tgcaagtaat
     8581 ggtgcaaaaa tctgtggaaa tatctgcgca gaaacacctc agcggctgat gcgagggcaa
     8641 atcgttctat caggaaaatc ggagtatcaa gcagtgatca atgcagttaa tcatcgaaaa
     8701 gaagagctga ttctttgtgc aaatgaaagt tatccttcaa tcgtgaaacg cgggggcggt
     8761 gttcaagata tctctactcg ggaattcatg gggagtttcc atgcatactt atctattgat
     8821 tttttagtgg atgtaaaaga tgcaatgggc gctaacatga tcaactcgat tcttgagagt
     8881 gtggcaaaca agttacggga gtggttccct gaagaagaga ttctattcag tattttaagt
     8941 aattttgcta cagaatcatt ggcttctgcc tgttgtgaaa tcccattcga acgcttaggg
     9001 agaaacaaag aaatcggtga acaaattgcc aaaaaaatcc aacaggcagg ggaatatgcg
     9061 aagcttgacc cttaccgtgc agcaacgcac aacaaaggga tcatgaatgg tatagaagct
     9121 gtagtggcag ctacaggaaa tgatacacgt gcggttagcg cttcgatcca cgcctacgcg
     9181 gcaagaaatg gattatacca aggattaaca gactggcaga tcaaagggga taaactagtt
     9241 ggaaaactaa cggtgccttt ggctgttgcc acagtaggcg gagcttccaa tatcctgcca
     9301 aaagcaaaag catctttagc tatgttagat attgattcag ccaaggaact agcacaagta
     9361 attgctgcag tagggttagc tcaaaacctg gctgctttgc gtgcattagt tacagaagga
     9421 atccaaaaag gccacatggg acttcaagct cgttcattag cgatctcaat tggggctatt
     9481 ggtgaggaaa tcgagcaagt tgcgaaaaaa ttacgtgaag cagaaaagat gaaccagcag
     9541 acagctatac aaatattgga aaaaatccgg gaaaaataaa aaagcaatat ctttagaaga
     9601 ataaagcaag atttacagtt attttattta ctgcagatct tgcttttttg gctcttcgtc
     9661 aaattgtgtt ggcgaagaca aatttgaata aaacttagtc cgatatgcgg cgcgttctgt
     9721 gcgccgcata tttttttagt tttcaaagat cagaccttgt tgtaaataga tccgtgcccg
     9781 aaagttataa aagttgcgat aaccaaacgc aattcgttta atcagcttga tcttgttatt
     9841 cagcccctca gtgacgccgt ttgagtgggg caccttaaag gcatttgaaa tacccgattg
     9901 gtagcgatgg aagatcgtga atttcttttt aaacgactga ggtaacgtag atgaaattgt
     9961 tttaagggtt tcttgaaagc cttccgta
//
LOCUS       DACGEU010000096         9962 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.098, whole genome shotgun sequence.
ACCESSION   DACGEU010000096 DACGEU010000000
VERSION     DACGEU010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9962)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9962)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9962
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.098"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            111..890
                     /locus_tag="IXR40_002371"
     CDS             111..890
                     /locus_tag="IXR40_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362175.1"
                     /translation="MEKPFVKSLTAVAVGAGAIAICLFGYHINNQRQHQQRINYAESA
                     ITNQKDTLTSLSKEVDKLYSTKEKIFLNPEITEETITSLSNKLSSVKLSADDYDIKES
                     ELPKEAVAIQDEKKAIVTQLDSAESKLKIQTAVNDLFTKNVSNWQQAVDDVIIKEKVT
                     SADVARVRENMSFFKDSPWKTVVMQYLGFADIQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTVLSQIEQIRNEKISAAYATKAQTVAEQMGYSNISY"
     gene            936..1880
                     /locus_tag="IXR40_002372"
     CDS             936..1880
                     /locus_tag="IXR40_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAQ4362176.1"
                     /translation="MARRRRKSRGKKIFLIILAVLIVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QTTIVSIPRDTYVDIVGRDTKDKINHAYAFGGAAMAMDTVQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFPIGKITLNGDQALSYSRMRYEDPNGDYGRQGR
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMNFDEMKKIALDYREAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            1896..2675
                     /locus_tag="IXR40_002373"
     CDS             1896..2675
                     /locus_tag="IXR40_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein kinase"
                     /protein_id="HAQ4362177.1"
                     /translation="MEETISLKEIFETLRKHLVIIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     EQIKDAISVNQAENSQMFSIQAISTNAVAAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLMTGLMLGMMVGVGLAFLLELLDRTVKDEKYVTDTLGFPILG
                     TVPEMSAKELNAGIRKKGPAQTQPKATNDKTAPSRRSRSRV"
     gene            2687..3385
                     /locus_tag="IXR40_002374"
     CDS             2687..3385
                     /locus_tag="IXR40_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HAQ4362178.1"
                     /translation="MARTQKQKAAQTHAVSLVTLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVIYKTFKLNNAS
                     GLSTVLSSSGSVADEIQRTPVDNLSILPSGPKPPNPSELLSSPRMDQILAEARQLFDV
                     VIFDMPPVVAVTDAQIMSSKTDGTLLVVRENTSRKESLTKAKELLDMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            3413..4177
                     /locus_tag="IXR40_002375"
     CDS             3413..4177
                     /locus_tag="IXR40_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HAQ4362179.1"
                     /translation="MIDLHCHILPGIDDGAENLEASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIHRDEILFTDLD
                     DTYLLIEFPTLEVPLYAERLFFELLELGKIPVIVHPERNAHFREDPNHLLPFLDMGCL
                     AQLTAPSYVGVFGKDIQKTAKTMVKHNLVQMAASDAHGVSKRTFYLKECYEQIAKEFG
                     KEKVVQMKQVAKDLINGDEINYPIYEEVKKKKFGLF"
     gene            4221..5672
                     /locus_tag="IXR40_002376"
     CDS             4221..5672
                     /locus_tag="IXR40_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HAQ4362180.1"
                     /translation="MYRKNSSGWSKHIDFILLDLFCVQLAFYISYVMRQGDWNPYVIP
                     IYRHMAIFIELENLTIIFLFEAYKNVLKRGYYKEAVASIKQSFMLLLVCSLYLITMQD
                     GNDYSRVSLFIMGVVYGLLTYIIRILWKGLLHHRMKNGEDVSLVIVTSQKIAKNVVRN
                     LKEKNYGMYKLSGVIVVDRDMYGTTIGGVPVVANADNAAEYLLQNWVDEVFINVDESV
                     PYPKELIARCSEMGLAVHMNLTKVSDSTRGKQFIGRVGDYTVITSSINVMTMRQAFIK
                     RTIDILAGIIGCIATGVIFIFVAPVIYIKSPGPIFFAQERIGQNGKTFKMYKFRSMYM
                     DAEERKAELMKENKMSNNLMFKMDFDPRIIGNKILPDGTKKTGIGQFIRSTSLDEFPQ
                     FYNVLMGKMSLVGFRPCLKSEYEKYDFHHRARIAMKPGITGMWQVSGRSDITDFEEVV
                     KLDAEYIRNWSMGLDFRILFRTVKTVLHRNGSM"
     gene            5704..6840
                     /locus_tag="IXR40_002377"
     CDS             5704..6840
                     /locus_tag="IXR40_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAQ4362181.1"
                     /translation="MARKKLKICMLGHKRIPSREGGIEIVVEELATRMVALGHEVTCY
                     NRSGHHVSGKEFDQHKNKEYKGVKLKTIFTLNIKGIAAMSSSVFGGIRAAFGKYDIVH
                     FHAEGPCAMLWLPKLFGKRCVATIHGLDHQREKWNKLASTYIMLGEKCAVKFADEIIV
                     LSESVQNYFEDIYGRKTRFIPNGVKKIEIKSAGLITEKYGLTKDSYILFLGRLVPEKG
                     IRYLIEAFKDVQTDKKLIIAGGSSDTDEFANELKELAKGDERIIFTGFVQGQELEELY
                     SNAYIYTLPSDLEGMPLSLLEAMSYGNCCIVSNISECTEVVEDKAMIFKKSDVSDLKI
                     RLEEACNQSEMVKVLKNQATEFICSKYNWDKIVQETLNLYRGNI"
     gene            6840..7946
                     /locus_tag="IXR40_002378"
     CDS             6840..7946
                     /locus_tag="IXR40_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HAQ4362182.1"
                     /translation="MIRILQCVNDMHRAGLETMLMNYYRNIDRTKIQFDFLTHRPYKS
                     DYDEEIISLGGKVYYAPRLYPQNYPKYFKWMEQFFKDHPEYEIVHSHIDAMSYLPLKA
                     AKKAGIPIRIAHSHNTSIDRDFKYLLKQYYRCKLTSVLTHEFSCGKVAGDFLFRNDKF
                     TLIPNAVDAKKFYYDESIRNDVRMKLGISSQTFVMGHIGRISYSKNHRFLIEIFKEFH
                     AIKNNSVLLIIGTGDMEEEIKNYAKKSGIDDDIKFLGNRNDIEKFYQAFDVLMLPSLF
                     EGVPLVGIEAQFADLPCFFSEKVPTEVAFSDKTNFISLNQSAKEWAREIANVDISHRD
                     SERSILIKADYNIQTAYKILESKYYELFELIQRG"
     gene            7952..8974
                     /locus_tag="IXR40_002379"
     CDS             7952..8974
                     /locus_tag="IXR40_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAQ4362183.1"
                     /translation="MTQKHSSIKRIIHRISEELNATRRIAKITSWKEAFATLQAKIDI
                     QVMNRNGYNESKKQKEHLLKKHEVMLKYYEKTFSDFLKTYDYSQNQIINQSKSPYSNC
                     IWVCWWQGLDQSPEIVKACVKSIKRNAGKHTVIILTEDNYRQYVDIPKWVEEKKNKGI
                     ITRTNYSDLLRLSLLAKHGGLWLDATFYCTKPIPDEYFDIDIWSIRRPDYAHASVASG
                     YFAGYSLACNQESRWMFAIIRDFFLNYWKNNDMMVDYLMIDYMIVLAQRINHEIAQTF
                     DKIPSNNPLCDELIKNLNNIYDEKVWNLLKKDTLLFKLTWKQSFKKQKDDKVTFYGML
                     VENKLL"
     gene            8996..>9962
                     /locus_tag="IXR40_002380"
     CDS             8996..>9962
                     /locus_tag="IXR40_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAQ4362184.1"
                     /translation="MKHKVSVIVPIYNVEKYLRKCVDSLLSQTLKEIEIVLVDDGSPD
                     ASGEIADEYQKKYSNVKTIHRENGGLGPARNTGIENATGEYVAFLDSDDWVESDMYEK
                     LYLVASKENADIVVSGHCDFANDKAMVKKQHPLSGNVYDTPNSIKNVRKNLFGHSPKD
                     QEVEAFPMSVCMSLYNKNLLDKYRLRFEKILSEDTIFNLNAYDVANKIAFTEYTDYCY
                     RKEEQESITKSLSPNKQTEFKEFLITLKAIASKEDLECQIRAKRMAIDYCRLYVGLVD
                     DANLGIKEKRKYIKKFIEDEGLIQCWKGYPTNTLPFQQKFFHKMLE"
BASE COUNT         3635 a         1421 c         2064 g         2842 t
ORIGIN      
        1 tttctgtgaa tatattagtt taattatgtt tttttaaata aaaagctgtc atttttatgt
       61 aagtgaatta tatcttaatt tatctatcat caatacttag gagtgaatct atggaaaagc
      121 cattcgtcaa gtcattgact gctgtggcgg taggtgcagg tgctattgcg atctgtttgt
      181 ttggatacca tatcaataat cagcggcaac atcagcaacg gatcaattat gcagaatctg
      241 ccatcaccaa tcaaaaagac accttgactt ctttatcaaa agaagtagac aagctgtata
      301 gtacaaaaga aaaaattttt ctaaaccctg aaataacaga agaaacaatc acaagtttgt
      361 caaataagct atcctctgtc aaactttcag cagatgatta cgacatcaaa gaatcagaat
      421 tgcctaaaga agctgttgca atccaagatg agaagaaagc aatcgtgaca cagttagata
      481 gtgcagaatc aaaactgaag atccagacag ctgtcaacga tttatttact aaaaatgtat
      541 caaactggca gcaagctgta gacgatgtca tcatcaaaga aaaggtgaca agtgcagatg
      601 tcgctcgtgt acgtgaaaat atgagctttt ttaaagatag tccttggaaa acggttgtta
      661 tgcaatatct aggattcgct gatattcaga tcgcgcaagt cacgcaacta gatcagttat
      721 tcgatacgat gttaaaggat ggtcaagtga ctgccaccgc tacttacgat caatatttga
      781 cggtgctcag tcaaatagag cagatccgga atgaaaaaat aagcgcagca tacgcaacaa
      841 aagcacaaac tgttgctgag caaatgggct atagcaatat aagctattga cagttaaaac
      901 gttgattcaa gcaaggttag caaacggagg aaactatggc aagacgaaga agaaaatcaa
      961 gagggaaaaa aatatttctg attattttag cagttcttat cgtattagta ttagcaattg
     1021 taggagtagg agcaaaatta tatctggatc tctcacattc tattgagaaa acttacgaat
     1081 cagtggaacg aacccaagga gaacgaacga aaccagttga tctggacaaa caagaatctt
     1141 tctctgttct attgatgggg attgatactg gagatttagg tcgggtcgat caaggaagat
     1201 cagatacgat gatggttgcc acagtcagtc ctgaagacaa acagacaacg atcgtcagca
     1261 ttcctcgtga tacgtatgtc gacatcgtag gtcgtgacac aaaagacaag atcaaccacg
     1321 cttacgcatt cggcggagct gccatggcga tggataccgt acaaaaatat gtagacatcc
     1381 caatcgatca ctatgtctct atcaatatga aagggctaaa ggaactcgtt gatgcagttg
     1441 gtggtatcga agtcaataat gacctcactt tctcacaaga tggctatgac tttccaatcg
     1501 gtaaaattac attgaacggg gatcaggcat tatcttattc tcgtatgcgt tatgaagacc
     1561 caaatggtga ttacggtaga caagggcgcc aaagaaagat cgtagaaggc gtagcgaaaa
     1621 aagtattgag tctaaacggt gtcagcaact atcaatccgt tttgaatgct ctagagtcga
     1681 atatgaaaac agacatgaac tttgatgaaa tgaaaaaaat tgctttagat tatcgggagg
     1741 catttggtac gattaagcaa gatcagctgc aaggagaagg cttcatgcaa gataatatct
     1801 cctatcaaaa agtcagtgat caagaacttg atcgtgtgaa aaaagaatta aaagatcaaa
     1861 tgaatctaga gaataaatag gaaagtggag aaaaaatgga agagacaatc agcttgaaag
     1921 aaatttttga aacattacgc aaacacttgg taataatcat catctcaatg tttgctggct
     1981 tggccatctc aggaatcgta acatttttca tcttgacacc aaaatacagt tcacaagcac
     2041 aattgatcgt gacactgcca caatcagaca ctgcaaatgt caatgatgtc aatacgaacc
     2101 tgcaaatgat caatacgtat aaagatatga tcgtcagtga tttagtgctc aatgaagtca
     2161 aagatcgttt agaaacagaa gacaatgtga aaatgactgc tgaacaaatc aaagatgcca
     2221 tctcagttaa tcaggcagaa aattcacaaa tgttctcgat tcaggcaata agtacgaatg
     2281 cagtggctgc tcaacagatc gctaacacaa cttcacaagt tttccaagag aacgcaaaag
     2341 atgtgatgaa tgttgataaa atctcgatca tttcaggtgc agttgccaat acgacacctg
     2401 tttcgccaaa taataaattg aatttaatga ctggcttaat gttaggaatg atggtaggtg
     2461 taggtctggc attcttattg gaattactcg atcggacagt gaaagatgaa aaatatgtga
     2521 cagatacatt aggattccca atcttaggaa cagttccaga aatgtcagcg aaagaattga
     2581 atgctggtat ccgtaaaaaa ggaccagctc agacacaacc aaaagctaca aacgataaaa
     2641 cagcgccatc acgcagaagc cgctcaagag tctaggagga aagaaaatgg cacgaacaca
     2701 gaaacaaaaa gcagcccaaa ctcatgcagt cagtttggtc acactcacca atccctcttc
     2761 accaatcgct gaacaatatc gtacgattcg gacgaatatc cagtttgcct ccgcagctgg
     2821 tcagcaaatc aaaacgattg ttgtgacttc atcaggacct ggagaaggga aatcgaccac
     2881 tgcagcaaac attgccgttg tttttgccaa atctggtcaa cgggtgctgc tagtcgatgc
     2941 agacttacgt aagcccgtca tctataaaac gttcaagttg aacaacgcaa gcggattaag
     3001 tactgttctt agttcatcag gaagtgtagc agatgagatc caacgaacac cagtcgacaa
     3061 tttgtcgatt ctgccaagtg gacctaaacc accaaatcca tcagaactac taagttcgcc
     3121 aagaatggat cagattttag cagaagcaag acaactattt gatgtagtga tcttcgacat
     3181 gccgccagtc gttgccgtaa cagatgcaca gatcatgtct tcaaaaacgg atggcacctt
     3241 attggtcgta cgggaaaata cgtcacgaaa agaatcattg actaaagcaa aagaactgtt
     3301 agatatggta caagcacgag tcttaggtgt cgtatacaac ggagcagaac acagcaaaga
     3361 tgctggttat tactacggaa attaaggaat aagaagagag gagacaagag aaatgatcga
     3421 tctacattgc catatcctac caggaatcga tgacggggca gaaaacttag aagcaagtat
     3481 tgcaatggct gaaaaagcga ttcagcaagg cattacgcat attttatgca caccacacca
     3541 caataatgga aaatacagca atgaaaaatc acaagtcatt tctctagtcg cttcgttaca
     3601 agccgaatta gagaaaagac agttgccttt gacgttattg gaaggacaag aagtacgtat
     3661 taccggaacg ctcatcgaag acatccaccg agatgaaatt ttatttacag atttagatga
     3721 tacatatctt ctgatcgaat ttccgacact ggaagtgccg ttatatgcag aacggctttt
     3781 ttttgagttg ttagaactag gaaagatacc agtgatcgtc catccagaac gcaacgcgca
     3841 ttttcgagaa gacccaaatc atttgcttcc gttcctagat atgggatgtt tggcccaact
     3901 tactgcgcca agttatgttg gtgtatttgg caaagatatc cagaaaacag ccaaaacaat
     3961 ggtcaaacat aatctcgtgc agatggctgc ttctgatgca cacggggtct ctaagcgcac
     4021 cttttactta aaagagtgct atgagcagat tgccaaggag tttggtaagg aaaaagtagt
     4081 acagatgaaa caagtcgcaa aggatctgat caacggggat gagatcaatt atccaatcta
     4141 tgaagaggta aaaaagaaga agtttggttt attttagttc tttattcgta gataaaaagg
     4201 aaatgaggag agagtgagag atgtatagaa aaaactcaag tggttggtct aaacatattg
     4261 attttatttt attagactta ttttgtgtcc agcttgcttt ttatatatca tatgtaatgc
     4321 gacagggtga ctggaatccg tatgtgattc ctatttatcg ccacatggca atttttatag
     4381 aacttgagaa tcttacgatt atatttttat ttgaggcata taaaaatgtt ttaaaaagag
     4441 gatattataa agaggctgta gcttctataa agcaatcttt tatgctgtta cttgtgtgca
     4501 gtttatacct tattacaatg caggatggaa atgattattc cagagtttct ttatttataa
     4561 tgggggtggt gtatggatta ttaacatata taattcgtat actttggaaa gggttgttgc
     4621 atcaccgcat gaaaaacggt gaagatgtat cgttagttat tgtaacatct caaaagattg
     4681 caaaaaatgt agttcgtaat cttaaagaga agaattatgg catgtataaa cttagtggtg
     4741 tgattgtagt agacagagat atgtatggaa ctaccatcgg aggtgtccca gtagttgcaa
     4801 atgctgataa tgcagcggaa tatcttttac agaattgggt agatgaagta ttcatcaatg
     4861 ttgacgaaag tgttccatat cccaaagaat taatcgccag atgttcggaa atgggacttg
     4921 ctgtacatat gaatcttaca aaagtgtctg atagtacacg tggaaaacaa tttattggcc
     4981 gagttggtga ttatactgtt attacatcta gtattaatgt tatgacgatg aggcaagcat
     5041 ttataaagag aacgattgac attcttgctg gaattattgg atgtattgca acaggtgtta
     5101 tttttatctt cgtagcacca gttatttaca tcaaatcacc agggccgatt ttctttgcac
     5161 aagaacgtat tggtcaaaat ggtaagacat ttaagatgta taagttccgt agtatgtata
     5221 tggatgcaga agaacgcaaa gcagagttga tgaaagaaaa taagatgagt aataatctca
     5281 tgtttaagat ggattttgac ccaagaatca ttggcaataa aatacttcct gatggaacaa
     5341 agaagacagg aattggacaa tttattcgat ctacatcatt ggatgagttt ccacaatttt
     5401 ataatgtcct aatgggaaaa atgagcctgg tggggtttag accttgcttg aagtcagaat
     5461 atgagaagta tgattttcat catcgtgcga gaattgcgat gaaacctggg attactggaa
     5521 tgtggcaggt gagtggtaga agtgatatca cagacttcga agaggttgta aaacttgatg
     5581 cagaatatat caggaattgg agtatgggat tagattttag aattttgttt aggacagtca
     5641 aaactgtgct tcatagaaac ggttccatgt aagataaaga tactatagaa ggagtaaaac
     5701 gtgatggcaa gaaaaaaatt aaaaatctgt atgctaggtc ataaaagaat tccatcaaga
     5761 gaaggtggaa ttgagatagt ggtagaagaa ttggcaacgc gaatggttgc acttgggcat
     5821 gaagtgactt gctataatcg aagtggtcat catgttagcg gaaaggaatt tgaccagcat
     5881 aaaaataaag aatataaagg tgtaaaatta aagactattt ttacattaaa tataaaagga
     5941 attgcagcaa tgagttcttc agtatttggt ggaattagag cagcattcgg aaaatatgat
     6001 attgttcatt ttcatgcaga aggaccatgt gctatgttgt ggttgccaaa actttttggg
     6061 aaaagatgtg ttgcaacaat tcatggtcta gatcatcaaa gagaaaaatg gaacaagctt
     6121 gctagtacat acatcatgtt aggggaaaag tgtgctgtaa aatttgcaga tgaaataatt
     6181 gtacttagtg aaagcgtcca aaattatttt gaagatatat atggaagaaa aacaaggttt
     6241 ataccaaatg gcgttaaaaa aattgaaata aaatcagcag gattgattac agaaaagtat
     6301 ggattaacaa aagattctta tattttgttt ttggggcgat tggttcccga aaaaggaatt
     6361 cggtatctaa ttgaggcatt taaagatgtt cagacagata aaaaacttat aatagccgga
     6421 ggaagctctg atacagatga atttgcaaat gaactaaagg aattagcaaa aggtgatgag
     6481 cgaattatat ttactggatt tgtacaagga caggaattag aagaattata tagtaatgcg
     6541 tatatctata cacttccaag tgatttagaa ggaatgccat taagtttgtt agaagcaatg
     6601 agttatggga actgttgtat agtttcaaat atctcagagt gtacggaagt agtagaagac
     6661 aaggctatga tttttaagaa atcggatgta agtgatttaa agataagatt agaagaggca
     6721 tgcaatcaat cggaaatggt taaagttttg aagaatcaag ctactgagtt tatttgtagt
     6781 aaatataatt gggataaaat cgtacaagaa acattaaatt tgtatagggg aaatatataa
     6841 tgattcgaat attacagtgt gtgaatgata tgcatcgtgc agggttggag acgatgctaa
     6901 tgaactatta taggaatata gatcgaacta aaattcagtt tgattttttg acacatcgtc
     6961 catataaaag tgattatgat gaggaaataa taagtcttgg aggaaaggtc tattatgcac
     7021 cgagacttta tccacaaaat tatcctaaat attttaaatg gatggaacaa ttttttaagg
     7081 atcatccaga atatgagatt gttcattctc atattgatgc gatgagttat ttacctttaa
     7141 aagctgcaaa aaaagctggg attccgatac ggatagcaca tagccataat acatcgatag
     7201 atagagattt taaatatctt ttaaagcaat attatcgatg taagttaacg tctgttttga
     7261 cacatgaatt ttcatgtgga aaagtagcag gtgatttttt gtttcgaaat gataaattca
     7321 ctttgattcc aaatgcagtg gatgctaaaa aattttatta tgatgaaagt attagaaatg
     7381 atgtacgaat gaaattagga atttcaagtc agacgtttgt aatgggacat attggaagaa
     7441 tttcatattc taaaaatcat cgttttttga ttgaaatttt taaagaattt cacgctatta
     7501 agaataattc cgtattatta attattggaa ctggtgatat ggaagaagaa ataaaaaatt
     7561 atgcaaagaa aagtggcata gatgatgata ttaaattttt aggaaataga aatgatatag
     7621 aaaaatttta tcaagcattt gacgtattaa tgttgccatc attatttgaa ggggttccgt
     7681 tagtgggtat tgaagctcaa tttgcagatt taccgtgttt cttttcggag aaagttccta
     7741 cagaagttgc tttcagtgat aagaccaatt tcataagttt aaatcaatcg gcaaaagaat
     7801 gggcgagaga gattgcaaat gtagatatct ctcatcgaga ttcagaacgt tcgattttaa
     7861 taaaggcaga ttataatatt caaacagcat acaaaatctt agaatcaaaa tattatgagt
     7921 tatttgaatt aatacaaaga ggttaaagaa tatgacacag aaacattcaa gtataaaaag
     7981 aattatacat cgcatatccg aagaattgaa tgcaacaaga cgaattgcaa agataacatc
     8041 ttggaaggaa gcatttgcca cgttacaagc taaaattgat attcaagtca tgaatcgtaa
     8101 tggatataat gaaagtaaaa aacagaagga acatttatta aaaaaacatg aggtaatgct
     8161 gaagtattat gaaaagactt tttcagattt tttgaaaaca tatgattata gtcaaaatca
     8221 aataattaat caatcaaaat caccatattc taactgcatt tgggtttgtt ggtggcaggg
     8281 attggatcaa tcgccggaaa ttgtaaaagc ttgtgtaaaa tcaataaaac gaaatgcagg
     8341 gaaacatact gttataattt taacagaaga taattataga caatatgttg atataccaaa
     8401 atgggtggaa gaaaagaaaa acaaaggaat cattacgaga acaaattatt ctgatttatt
     8461 aagattatct ttgctagcaa aacatggagg tttgtggtta gacgccacat tttattgtac
     8521 aaaaccaata ccagatgagt attttgatat cgatatttgg tctattagga ggcctgatta
     8581 tgctcacgca tccgtagcat caggatattt tgcgggttat tcattagcat gtaatcaaga
     8641 gtctagatgg atgtttgcta taattagaga ctttttttta aattattgga aaaataatga
     8701 tatgatggtg gattatttga tgatagatta tatgattgtt ttagcacaga gaataaatca
     8761 tgaaatagca cagacatttg ataaaatacc tagtaacaat ccattatgtg acgaattgat
     8821 taaaaattta aataatatat atgatgaaaa agtatggaac ttattaaaga aagatacttt
     8881 actgtttaag ttgacatgga aacaatcttt taaaaagcaa aaagatgata aagttacttt
     8941 ttatgggatg ttggtagaaa acaaattatt ataaatatta gaggtataaa aagttatgaa
     9001 acacaaggta agtgtgatag taccaattta caatgttgaa aaatatttaa gaaaatgtgt
     9061 ggatagttta ttgagtcaga cattaaaaga gatagaaatc gtattagttg atgatggttc
     9121 gccagatgct tcgggggaaa tagcagatga gtatcaaaaa aaatattcta atgtaaaaac
     9181 aatacataga gaaaatgggg ggttaggacc ggcaagaaat acaggaattg agaatgcgac
     9241 aggagaatat gtggcttttc ttgattcaga tgattgggta gaaagtgata tgtatgaaaa
     9301 attatactta gttgcgtcca aagaaaatgc tgatatagta gttagtggac attgtgattt
     9361 tgcgaatgac aaagctatgg tgaaaaagca acatcctttg agtgggaatg tatatgatac
     9421 gcctaatagt attaaaaatg tacgaaaaaa tttatttgga catagtccaa aagatcaaga
     9481 agtagaggcc ttcccgatgt cagtatgtat gtctttgtat aataaaaatc tgctagataa
     9541 atatagacta agatttgaaa aaattttatc tgaagataca atttttaact tgaatgcata
     9601 tgatgtcgca aataaaattg cttttacaga atatacagat tattgttata gaaaagaaga
     9661 acaagagtct attacaaaaa gtttatctcc aaataagcag acggaattta aagaattttt
     9721 aataactcta aaagctatag catcgaaaga agatttagaa tgtcaaatca gagcaaaacg
     9781 tatggcaatt gattattgta ggctttatgt gggcttagtt gatgatgcaa atttgggaat
     9841 taaagagaaa agaaagtata taaaaaaatt tattgaagat gagggattaa ttcaatgttg
     9901 gaagggatat cctacaaata cgctaccatt tcaacaaaaa ttttttcata aaatgcttga
     9961 at
//
LOCUS       DACGEU010000097         9887 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.099, whole genome shotgun sequence.
ACCESSION   DACGEU010000097 DACGEU010000000
VERSION     DACGEU010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9887)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9887)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9887
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.099"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(109..2229)
                     /locus_tag="IXR40_002381"
     CDS             complement(109..2229)
                     /locus_tag="IXR40_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HAQ4362185.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLARGKNVIYIHLESFQQFLIDYKLTDENG
                     LQHEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYTSAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHNG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            2459..3637
                     /locus_tag="IXR40_002382"
     CDS             2459..3637
                     /locus_tag="IXR40_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HAQ4362186.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIIGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            3653..4411
                     /gene="aroD"
                     /locus_tag="IXR40_002383"
     CDS             3653..4411
                     /gene="aroD"
                     /locus_tag="IXR40_002383"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HAQ4362187.1"
                     /translation="MVRVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLVGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            4434..4919
                     /gene="ybaK"
                     /locus_tag="IXR40_002384"
     CDS             4434..4919
                     /gene="ybaK"
                     /locus_tag="IXR40_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HAQ4362188.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSRIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(4990..6243)
                     /locus_tag="IXR40_002385"
     CDS             complement(4990..6243)
                     /locus_tag="IXR40_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAQ4362189.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            6360..7709
                     /gene="gdhA"
                     /locus_tag="IXR40_002386"
     CDS             6360..7709
                     /gene="gdhA"
                     /locus_tag="IXR40_002386"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HAQ4362190.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNVQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            7821..9167
                     /locus_tag="IXR40_002387"
     CDS             7821..9167
                     /locus_tag="IXR40_002387"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HAQ4362191.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(9475..9861)
                     /locus_tag="IXR40_002388"
     CDS             complement(9475..9861)
                     /locus_tag="IXR40_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAQ4362192.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYPEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
BASE COUNT         3148 a         1800 c         2025 g         2914 t
ORIGIN      
        1 ctgagccaga atgaggttca ttctgaccca gatttgattt tgtacaaccc atcagtcctt
       61 attgacaaag agcctaattt tgtcgctgct ccttttaaat ttattttatc attcggaaga
      121 acttgtggtc gttccgtgaa gttcttggta cgtttgcgtt ttataaagat caacagttga
      181 ttgtccgttg tgttcactaa agacactagt tgacttgtca ccaagagatt tttcagcttc
      241 ttttaatttc tctaagccat tcttgtagtc ataatcactg gtatcaattg ggtctaatcc
      301 actattcgta tagaaccgaa gaagatcacc attattgatt tggtcagaaa cagctaactg
      361 tttatcaact ttttctttca gtgaatcaat ttcattctgt acttcctcag taggttcagt
      421 aatagcttca ccagtttcgt tactatagat cgtaccaccg tagtaagtat attttggtgt
      481 aacaaaatca ccatcacgga aagaaacaag ctgttcatga tctttcgaga atagatcttg
      541 tcctaactga atataatttt ttgtatctac acctagtaag tgaagtaatg taggcaaggc
      601 atcaacttgt ccgccgtaag tgtgattgat tccgccctgt gtttgtccag ggatatggat
      661 catataaggg acacgctgca tttgtgcatt gtcgtagttt gtccaagtag aacttgtttt
      721 tccaactaat tcagctagat ttttatttct tgaattcgag acaccgtaat ggtcaccgta
      781 aaggacgatg actgaattat catacaagcc gctttctttc aaataattga agaattcttg
      841 tacggcggta tctaaataat tggctgtcgc aaagtaaccg ttgatcgttt catcatttgt
      901 attggctaac gggaatcctg cttcgtcatt ggtgaatttt gaataaggat aatggttaga
      961 tacagcaatg aattttgaat aaaatggttg ttgcagacgt tccaagtatt gtacggattg
     1021 ttggaaaaat ggtttatcat gcaacccgta ttggaacgaa ttgtcatcat taacatcata
     1081 ataagaagaa tcaaagaaat aatcatatcc taaattcttg tatgtctcgt ttcgattcca
     1141 gaatgtacca gcgttcccat ggaataccgc actagtgtaa ccttgtgttt gacttaaaat
     1201 atcaggtgca gcttggaaag tattttttcc gcctaattgt gtgaacaagg agccttgatt
     1261 caagccaaac aatgaatttt ccatcagcgt ttccgcatcg cttgtttttc ctgcttttac
     1321 ttgatggaaa aagttgtcaa aactgaacgt gctgttgctg tggtaaagac tattgatgaa
     1381 aggtgtaact tcatgctgga gaccattctc atctgtcaat ttataatcga tcaggaattg
     1441 ctggaagctt tctaaatgga tataaatcac attttttcct ctagcgagcc cgaacaaatc
     1501 gtcatttggt gctgcataat gttcttttac ataattttct acttctttca tatcattggg
     1561 acttgcttct gcccgcactt ggtttgtctg gtaagtttga acaccgtcat aaaccatgaa
     1621 agcattcaag ccaagatatt tgaccaaata atcacgagag aatgttcgag tcagcaattc
     1681 tggacgatca gcttccgcca taaaaagatt tcctgagaaa atcataactg ctaatgtaga
     1741 gatcgcaaaa gccattcttg ctcggatcgg gcgagggtcc aacttgattt tttttgcaat
     1801 cagcagaaca gtcaagataa taaaatcgat ccaatagatc acatcatatg ggcgaaacag
     1861 tcgaatggca ctttctccca gaccactcgc tactttccca gcacctaaaa tcgtgttgat
     1921 cgtaatgaag tccgtgaatt ctcgataata agtgacattc gaaaaaacaa gcaatgtcaa
     1981 aagaaaataa atgaccatca tcgtgatata agcaactcta gggcgtctga tataaagagc
     2041 aattccaagt aataacaatg tagttgcaat agggttgata aacaagataa agtattgaat
     2101 gccactttcg attccgagat ggaaatcaac taaataggca aaaatcgttt tcaaccaaag
     2161 taaaacgact agtaaagaaa aaaatccgag cctcttattc aaaaaggcag gtgtttttat
     2221 acatttcaag ataatcttcc tttctgcact tcttaatcac agaagtgtcc tgaaaccatg
     2281 ttacacagct cacttattct catttatttt actagtatga caatatagtg tcaattgaaa
     2341 ccagaagttt atgctgtttc attaaggttt tctttaagct tcatgaaaaa atgagcagta
     2401 agacaagtcc tatgtttttt gttatacttg ggaagagaaa gctaaagcag gtgaaggaat
     2461 gaaagtaaaa gtaaaaaaaa gagcaagcaa tcgattgaaa aaaggatatc cactgatcca
     2521 aaaagaagac cttgctcatc cccaaaaaga aaccacgcaa tgggtggaat tagttgattc
     2581 gcaaaaccaa tttatcgcaa aaggatatct aggaaagcag aataagggaa tcggttgggt
     2641 attgagccag cagaacatcc catttgatca atcttttttt gaagaatttt ttgtgaagtc
     2701 aaaagaaaaa agaactttct ttttttcaga tgattctact accgcttttc gtatattcaa
     2761 tggagaagga gacgggatcg gcggtctgat tgttgattat tatgcaggtt atgctgtttt
     2821 ttcttggtat aacgaaacgt tatatgcaca tcgtgaatta ttgattcaag cttttcgtga
     2881 aatctacccg gaaatcatag gaggctatga gaaaattcga tttgaatcag taaatctgcc
     2941 tgagagccag ttcatttacg gaaaagaggc accggaaccc ttgatcgtaa aagaaaacgg
     3001 agtaaaattt gccgtttatt taaatgaagg attaatgact gggatctttt tagaccaaaa
     3061 agaagtacgg ggatcattag cagaaggttt cgcttctggg aaaacagttt tgaacatgtt
     3121 tagttatacc ggcgcctttt ctgttgctgc cgcaatggga ggggcaatcg aaacaacaag
     3181 tgtcgatcta gcaaaacgca gtttaaaaaa aacacaggaa cagtttgaag tgaatggttt
     3241 ggatgtcgat cagcaaaaaa tcattgttat ggacgtattc gagtatttca aatacgccaa
     3301 aagaaaacaa tttttatatg acatgattgt attggatcca ccaagttttg ccagaaataa
     3361 gaaaaaagtc tttcgcgtag caaaagatta tggggaactg gtcaaggata gtctggatat
     3421 tttagcagaa gacgggatac ttattgcgtc tacaaatgct gcgaatgtct cgatagaaca
     3481 attccaaaca atgattgaag aggaattcca tgccaaaaat gtttcttttg aacaacttgc
     3541 tttatatcgt ctgccaaaag atttccagac gacggatacc tttttagaag gcaattatct
     3601 gaaagtgttt gtttatcaaa ttaaaaataa ccattagaag gagcgatgca gaatggttcg
     3661 ggtaaaggga ttgaatatag gaagcggtag accaaagatt tgtgcgcctc ttatcggggc
     3721 cgtccgagag gaagtattac gtgaagcagt tcttgcacgt gaagcagggg ccgatttagt
     3781 cgaatggcga gtcgatcatt atcgtgaagt tttttctttt gatgaagtag cagaaacatt
     3841 ggttcttatc catgagatgc ttgatggact gccgttatta tttacgtttc gtaccttagc
     3901 tgaaggcgga gaacaagaca tatcgatccg tcagtatcgc gacctttatg aacatgtgat
     3961 acacacagga ttagtagata tggtcgatat cgagttgttc aaagtagaaa gtctaggaaa
     4021 aagactgata gaggaaatca agtctttaaa cattccttta attatcagta gtcatgattt
     4081 taaagaaaca ccagcagacc ctgtcttgct ttaccgattg aatgttatgg aacattttgg
     4141 agccgatatc ggaaaactgg cagtaactcc caataatgaa cgagatgttt tgcggttgat
     4201 ggagttgact agacgggcaa atgcttttgt ctccatgcct attattacga tgtccatggg
     4261 aaatcttggt aaaatttctc gtctggttgg cggaacgacg ggttccgtta tgacatttgg
     4321 ttccttaagc agcgattcta cttctgctcc aggacaatta ccggtcaaag cattgaagca
     4381 aattattcaa ttattaaatg aaccgttgta gaacaagttt gaggtgatat tttttggcaa
     4441 agaaaaaaat agtaaaaacg aatgcaatcc gtatggtcga acaaaaaaag attccctata
     4501 cagagcacga atatgagtgg gacgaaagcc acctaagtgc gtcatcggtc gctgaacagc
     4561 ttccagaaag ccaatctcgt atatttaaaa cactggttgc tgtgggcaat gtgacggggc
     4621 ctcttgttgc tgtgataccg ggagaagccg aattgaatct aaaaaaatta gcaaaagttt
     4681 cagggaataa aaaagtagaa atgctccatt taaaagattt ggaagcaacg accggataca
     4741 tacgtggtgg ctgctcgcct ataggtatga aaaaactatt tcctacttat ttagatcaaa
     4801 ttgcagaaag ctatgaacaa atcattgtct cggctggcag aagagggcta cagatggagt
     4861 tagcacctca agatatctgt gcattaacga gcggacaatt tgcagatata aaacaataaa
     4921 tcatacgtat aaaagaaaga aggaggccgg gatgttgttt gtccagtctc cttctttctt
     4981 ttttatacat tatgctcttt gcccggcatt cattcctgct acatgccctg tagcgaaagc
     5041 cgctgtgata ttaaagccgc cagtataacc attgacatcc agtaattctc ccgcaaaata
     5101 cagaccatca atgattttac tctccaatgt tttaggataa atttccttta gagaaacccc
     5161 tccgccagtt acaaatgatt tctcaatagg aaaagttttg ttgattgata gcttaaactc
     5221 tttgcatagt tgaacaaaat cttgaatttg tttttgagag gcttgttgtc ctgtcagatg
     5281 atccatttca agccgctcaa gaaagaaaac taacaatcgc tcaggcaata taccatgcca
     5341 agcattgacc aagttctttt tggttgcttt acttttttct gtcaatatat gaataagctc
     5401 ttgtttggtt tgtgtaggga aacaatccag agaaagtgtc actggttctc ccgttttctc
     5461 taattcttta ttgacaaaac ttgaacaacg cagtgcagcc ggaccagaaa taccgaaatg
     5521 ggtgaaaagt aaatccatcg tatgttcagt caatacacga ccttttttat ttaaaacgcg
     5581 taaagtgatg tcttgtaaag aaagcccttg aagtgttttc tcctgaatat acggttcatc
     5641 cgatatcaag ggggactctg tcgcataaag aggcgtcacc gtgtgaccca ctcgcttcac
     5701 gatcttgtac ccatctccag tagaaccagt agatggataa gtccgtccac cagttgttaa
     5761 gataatggca ggagcatgga actcttcgaa ttccgtgcgt ataccgtaaa ttttatgttc
     5821 tttgtggatc aatttctcta ctcgagtaga gaatagaagc gtcacatcta gttctttcag
     5881 acgattgagc aatgcttcga taatcgtttt tgatttattt gttacaggaa acatccgtcc
     5941 atgatcctct tcttttaaat gtacgccttg tgattcaaag aagttcatga tatcgaaatt
     6001 attccattgc gcaaacgtac tatataaaaa ctttccattt ccaggaatat gtgcaatcaa
     6061 atcatcaaca ggacgattgt tcgtaacatt gcaccgacca ccacctgtca tcagtagttt
     6121 ttttcctgct tttttgtttt tttcgatcaa gagtacgcgt gcgccttgtt cagctgcact
     6181 gatcgctgcc atcatcccgc ttgttccagc gccgactacg atcacatcat acagtttttc
     6241 cattccctca cctcaaggaa agtgtagcat atctgaagaa agaaaacaga aaaaaatgtt
     6301 ttgagccaaa agagaaaatg agctaaaatg agggaagata agcaaaggag cgtggaacga
     6361 tgacaaacgc aacagaatat gttcaagcaa ttcaagaaaa gctacatcaa aaggatcaag
     6421 ggcaagaaga atttttacaa gcaatcgatg aattcatgcc cacggttatg tcttttttgg
     6481 acactcatcc cgaatatatc gaaaagaata tcttagaact tttaacggaa ccagaaagag
     6541 ttattcaatt tcgagtgcct tggcaagatg atgaaggaaa ctggcgagta aatagagggt
     6601 accgtatcca atacaactca gctatcggcc cttataaagg tggattgcgc ttccatccta
     6661 gtgtcaatct aagtatcttg aaatttttgg cttttgaaca gattttcaag aatagtttaa
     6721 ccggtctgcc aatcggtgga ggaaaaggcg gaagtgactt cgatcctaaa ggaaaatctg
     6781 ataatgagat catgcgtttt tgtcaaagtt tcatgctgga attgtcaaaa catatcggcc
     6841 catcgattga tgttcctgcg ggagatatcg gtgtaggagc tagagaaatc ggctatttgt
     6901 tcggcgaata taaacgattg aaaaaatatg atactggtgt gttgacaggt aaacctttgg
     6961 atttttgggg aagtaagata cgtacggaag ctactggtta tggattagtg tattatgtca
     7021 aacatctatt gaacgaagaa aaagattcat ttaatcaaaa aacagttttt gtttccggaa
     7081 gcgggaatgt agccatttat gcaatcgaaa aagtgcaaga gctaggcggg aaagttgtta
     7141 catgttcaga ttctagcggg tacatctatg atccagaagg aatagatgtg aaactattga
     7201 aagaagtcaa agaaatcaat agacaacgtt tgacggaata cgcaaaccaa cgtccttctg
     7261 ctatttatca tgctggagaa tctgtttgga cattgaaaga aaaagcggat atcgctttgc
     7321 catgtgctac tcaaaatgaa atagacgaaa gcttggccga aatcttagta gaaaatggga
     7381 tcaaaatcgt agcagaaggc gctaatatgc catgtacagt aaaagctgtt tctgttcttc
     7441 atgaagcagg cgtgtggtat tgtccaggaa aagctgctaa tgctggagga gtagcagtat
     7501 ctgctttaga aatgagtcag aacgtccagc gattgacttg ggaaagagag caagtggatg
     7561 agcagctgga tcaaatcatg gaaacgattt accatacgtg tcgccaaaca gcagccgagt
     7621 acggcgacga aaaaaatctg cttcttggag caaatgttgc tggatttgaa aaagttgcca
     7681 aagcaatggc agcagaaggt ttagtttgaa aaatgaaact ttcttggaaa tattgtcagc
     7741 attttgttta tttgcttgaa aaataataaa aaaaaacgta aagtattacc tgtagagtaa
     7801 acctataagg aggagaacaa atggcacaca ttcattttga ctattcaaaa gtagcaccgt
     7861 ttgtcaacga acaagagtta gggtacatgc aaagccaagt aacagcagcc cacaacgaat
     7921 tacgggaagg tactggcgca ggaagcgact tccgcggctg gatcgattta ccaacgaact
     7981 atgacaaaga agaatttgca cgtatcaaag aagcagctaa aaaaatccaa tctgattctg
     8041 aagtattagt tgttatcggt atcggtggtt cttatttagg cgctcgtgca gcgatcgact
     8101 tcttgaatca cacattcttc aatttattag atagcaacac aagaaaagca ccacaaatct
     8161 tctttgccgg aaattcaatc agctcaacat atattgctga cttgatcgaa gtaatcggtg
     8221 atcgcgactt ttcagtaaac gttatttcaa aatctggaac aactactgaa ccagcgattg
     8281 cgttccgtgt attcaaagag cttcttgtta agaaatatgg acaagaagaa gcaaacaaac
     8341 gtatctacgc tacaacagat aaagcaaaag gtgcagttaa agtagaagca gatgcagaag
     8401 gttgggaaac tttcgtgatt cctgatgaca tcggcggacg tttctctgta ttaactgctg
     8461 ttggtttgtt accaatcgct gttagtggtg cagatatcga tgcattgatg caaggtgccg
     8521 ctgatgcaag caaagcatac tcaagcgaca aactagaaga aaacgaagct taccaatacg
     8581 cagcaatgcg caacattctt taccgtaaag gcaaagtaac tgagttgttg atcaactatg
     8641 aaccaggaat gcaatacttc tcagaatggt ggaaacaatt gtatggtgaa tctgaaggaa
     8701 aagaccaaaa aggcatctat ccttcaagcg caaacttctc aactgatttg cactctttag
     8761 gacaattcat ccaagaagga cgtcgcaata tttttgaaac agttgtgaag gttgaaaaac
     8821 ctcgtaaatc aatcacaatt cctgaacaag cagaagattt agacggtcta ggctacttgc
     8881 aaggaaaaga agtggacttc gtaaatacaa aagcatttga aggaacattg cttgctcata
     8941 cagacggtga cgtgcctaac ttgctagtca aaattccaga aatggatgct tatacattgg
     9001 gttatacaat gtacttcttt gaaattgctg taggtatttc aggttacttg aatggaatca
     9061 acccattcga ccaaccaggt gtagaagctt acaagaaaaa catgttcgca cttctaggca
     9121 aaccaggctt tgaagatctt gctaaagaat tgaacgaacg cctgtaagat aagggttttt
     9181 cgctagattt aaataatcag tgatagaaac atgttcgctt taaaatgaaa actggtaccc
     9241 atttaggtac tcaaacatac tgcatcgttt attcagaata aggggctgtg acaagacgtt
     9301 tgtcacagtc ccttgtttgt atagaaatcg attgattgcc ttgctcttta gtttgtttta
     9361 ggactttaag aacagtgagg ctgacttcga aggttaattc tgtttttttg ttttctagaa
     9421 tcagtaagca aaaaagcact cacttcgagt gcttttttgc gatatattct tagcttaaga
     9481 taggcctaat ttttctttta cagatgaggg taccttatcg ctggtaatta cttttttctc
     9541 tatgatccgc ttttcgcttg ctttcaactg caagatcgtt ccttcggggt aagcagaacc
     9601 attggcagag tcaccagaag taatgacatc gaaatctaac tgtctttttt caccgttttc
     9661 agcataagca tctacgttgt atttaaaacc tcttccaatt acttccccat tatctgcttt
     9721 gatatcagtt tctgcaggca ttggagcttt gactaccgca taataatctt tacctacata
     9781 agtagactga tagtagtccc aacctttcca tcctataaaa gcaatcaata tgataacgat
     9841 caaccctaaa atttttttca tgaaagatct ccttttttat ttttatt
//
LOCUS       DACGEU010000098         9870 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.100, whole genome shotgun sequence.
ACCESSION   DACGEU010000098 DACGEU010000000
VERSION     DACGEU010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9870)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9870)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9870
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.100"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(18..263)
                     /locus_tag="IXR40_002389"
     CDS             complement(18..263)
                     /locus_tag="IXR40_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362193.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(378..956)
                     /locus_tag="IXR40_002390"
     CDS             complement(378..956)
                     /locus_tag="IXR40_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAQ4362194.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSIISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(1033..1563)
                     /locus_tag="IXR40_002391"
     CDS             complement(1033..1563)
                     /locus_tag="IXR40_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HAQ4362195.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(1567..2427)
                     /gene="rlmB"
                     /locus_tag="IXR40_002392"
     CDS             complement(1567..2427)
                     /gene="rlmB"
                     /locus_tag="IXR40_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HAQ4362196.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(2420..2815)
                     /locus_tag="IXR40_002393"
     CDS             complement(2420..2815)
                     /locus_tag="IXR40_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HAQ4362197.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(2812..4224)
                     /locus_tag="IXR40_002394"
     CDS             complement(2812..4224)
                     /locus_tag="IXR40_002394"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HAQ4362198.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(4221..4757)
                     /gene="cysE"
                     /locus_tag="IXR40_002395"
     CDS             complement(4221..4757)
                     /gene="cysE"
                     /locus_tag="IXR40_002395"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HAQ4362199.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     gene            complement(5079..6539)
                     /locus_tag="IXR40_002396"
     CDS             complement(5079..6539)
                     /locus_tag="IXR40_002396"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HAQ4362200.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(6709..7866)
                     /locus_tag="IXR40_002397"
     CDS             complement(6709..7866)
                     /locus_tag="IXR40_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HAQ4362201.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(7900..9270)
                     /gene="radA"
                     /locus_tag="IXR40_002398"
     CDS             complement(7900..9270)
                     /gene="radA"
                     /locus_tag="IXR40_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HAQ4362202.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKIAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(9333..9860)
                     /locus_tag="IXR40_002399"
     CDS             complement(9333..9860)
                     /locus_tag="IXR40_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HAQ4362203.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
BASE COUNT         2507 a         2213 c         1784 g         3366 t
ORIGIN      
        1 tcaggctcgt ttgcttttta aactgcttca gttaaaaatt cgatctcaac tgtccgagta
       61 agtacatctg aatagctgta agatactcgt tcaaaagaat tttcttcagg atccaaatca
      121 acaacgaata ctgaaggata ggtttctgtt aaaacgccgc ggcgttctgt ttgacgcttt
      181 cttcctgtct gagcaaccaa catgattggg ctgccgatac gaccttctaa atctttcttg
      241 attgaagcta aagttgttgg catacagttc acctctacta tcaactatac cacatatttt
      301 taaaattttc aagtttacca taaaaaaaaa agaaatgcaa taaaaataaa taagaagctc
      361 attaagattt ttctaaatta ttcctcatta taaaatttca agtgtttttt tattttgagt
      421 tttactctcc cgtaagcgct cattacttgc ttgtgatcca ttgctaaaca ttcagccatg
      481 tctacaaaat caacgccttg catataataa tgaaaaattt tagcttctat ttttgaaaac
      541 tggatttcgc aattttcgat tgcttctttt aataaaagat gctgaatcgc taaaggttct
      601 tgcaatgtga tctctgctaa aaagtctggt ccttctgtct ctattttttg gtcgattgag
      661 acttcatctt tttgatcacg acgcttcagc gcgttctgct tcctcaacag agaatagatt
      721 tgattgctta taatgctttt ataataactt ccaaagctaa cacctttgct tttttcgtaa
      781 gttctcaatg cctgatataa agcgatcctt gcttcttgtt cccaatcctc agaaacataa
      841 tttcttaaat aataggtgtt tttcaaacgt agtaaaagtg gaaaatattt ttgatacagg
      901 gcagcaaatg cttcttcgtc accattacgt gcagcgcgca ataactcctc agacataaaa
      961 taattcctcc ataaattcgt ttatggagga atcttatcat caatgattca tcgaactgat
     1021 tagaacgata tgttatttat tttttctcat taaatcgtcc aatttttggg acaatttttt
     1081 taactgctct tcattccatg gagaattacg tcggaaatca ataaaatgca tatctttatt
     1141 ttcttgggct attgtttttt ccgttttttt tatcgtctta tataattcat aagcagaagt
     1201 tcgtaatgct ccttgggaaa agatcatcca ctgttctgct aaatcgcttg tcgccactgt
     1261 cacttgtgtc aaacggtcat tcagctgacc agcgattctc tcgatataac tgtcagccgt
     1321 ttcgtcttct ttcgtaaaaa caacatccaa ctggtatttc ttataatttt gttggatgcc
     1381 cggaactagt tgggcatcga agacaacgat gacttccatt ccttcatatt tcgcataatt
     1441 tgataaacga tgtaaaagag cttctcttgc atccgccatt ttgtcctgct ttttaagctg
     1501 gacaagttcc ggccacgaac caatcatgtt gtagccgtct acaatcaaca gctgtttttt
     1561 catggtctac tccccctgac gttgggaaaa agcctgatac ataagcaaac cagcagcaac
     1621 actggcattt aagctctgga cgtgcccggt catcgggatc gtcagcaatt catccatttc
     1681 ttttttcaat cctggactca ttcctttgcc ttcattacca atgactaaag caattgatcc
     1741 tttggcattc catttttgga agtttgtgcc ggtcatatct gtgccaaata cccaaaatcc
     1801 tgtttctttg agctgttgca cagcttgtac caaattcgtc acgcgtgcaa cagggacatg
     1861 ttcgactgcc ccagtggaag tctttgttac gataggtgtg attccaactg ctcggtgttt
     1921 tggtatgatc acaccatcga cgccacttgc gtctgctgtc cgtaaaatcg acccaaaatt
     1981 gtgtggatct tcgatgctat ccaaaatcaa aaagaagggg tcttcttttt tctcttttgt
     2041 tcgttcaatc agttggtcaa gggataaata ttcataaggt gtaatcgcaa gaacgactcc
     2101 ttgatgcacg ccgtgatcgc tcaaagtttc taatttttgt ttaggaaccc atttgactgg
     2161 cacagcttgt tcacgtgcga tttctttcag ttcttctact ttttctcctc gtgaatcttc
     2221 ttgaagaaag agtttattcc ctcgcccttg ttgtagcgct tctactgcgg catggtgccc
     2281 aaagacgaaa ttatcttcta atgcttcttc attttgatca gaaactgact gatttcgtcc
     2341 agtttgcttt ttatttgaat atctattttg ttttttgtct tcaaatccac gtttcgattg
     2401 atgtttgttt gttctttctt tacccatttt tttcaccaac tttctgaata caccagcgga
     2461 tcaattcttc catccgctcg gtttgttttg tcaaatgcag atagcccatg agcgcttcga
     2521 accctgttgc gacccgatac gtcgtaacat cagcattttt tgcgctcgta tggcttttag
     2581 catttcttcc tctgcgataa taaagttctt cttcttctgt caaaagatgt tcttccagca
     2641 tttgctgaat caaaaaggct tgtgcattcg cagaaacata attcgttgcc gcacgatgca
     2701 gcttattggg ttttgtttct ccttgatcaa tcaggtggtc acgaacatag atttcgtaaa
     2761 tcgcatctcc aacataagcc aaggctaaac cgttcaattg tgtgtaatct ctcatgcttc
     2821 tcttctccat cgggttcctt gcggtgtatc ttctaataag atcccttttt ctttcaacaa
     2881 atcacgaatt tcgtcgcttc ggacaaaatc acgattgctt cttgcttgat ttcgttcttc
     2941 gatcaattgt tcaatctctt catctaataa ctcttctgct gtaaataaaa taccgaagat
     3001 cgaaagccat tgcgagaata aagcttctcc ttgtgccaag acagcggcag aaactttcgg
     3061 ctggtctaga taagtgttca gccacttagc aagctcatag accactgtga tcccatttgc
     3121 tgcattaaaa tcatcgtcca tttcttcgat gaatcgctgt tctaaatttt ctaacaaagc
     3181 gattttatcc gcatcatctg ccaaattctc tgaggcagtt tcttggcgga atttcaaatt
     3241 gtcaaacgta ttcttcagtc gttgtaaatt ggtggctgct tctttcatcg tcgtttcact
     3301 gtagcggatc ggacgacggt attgtgtggt cgccatgaag aaacgcaaga cttgtggatc
     3361 aacgtttttg atcatttcat gtacagtgat gaaattccct agagatttac tcattttttc
     3421 atcgtcttcg ccaatcgtta catagccatt gtgcatccag taattagcga attttttccc
     3481 tgttttcgct tcactttgtg cgatttcatt ttcatgatga ggaaattcta aatcttgccc
     3541 gccaccatgg atatcgatcg tttctcctaa atgttttgtt gccataacgg aacattcaat
     3601 atgccaaccg ggacgtcctt tgccccatgg tgaatcccaa gaaatctcgc caggttttgc
     3661 ttgtttccat aaagcgaaat ctaatgggtc ttctttttgc tgctgttctt cccctgtacg
     3721 ctgacttgct ccgacttcca gttcatcgat ggattggtca cttaatttcc cataattttc
     3781 aaatttacgg gtacggtaat acacatcacc tgaagattca taagcatagc ctttttcaac
     3841 caacacttga ataaatgcta aaatatctgg catatgatcc atgactcttg gatgcagtgt
     3901 agcaggctcg acattcaacg ctttcgtatc ttcttcaaat gctcggatga aacgatcagc
     3961 aacttctggt gctgtaatac ctaattcgtt tgctgtacgg atgattttat cgtctacatc
     4021 cgtgaaattc gatacgaaat cgactttata gcctcgatat tcaaaatagc gtcgaattgt
     4081 atcgaaagca atggtgctac gagcatttcc gatatggata taattataca cagtcggtcc
     4141 gcagacatac ataccgacat gtcccttttg tatagggatg aattcttctt tttttctggt
     4201 caatgtattg tagattttta tcattctgat ctcctcactt tttctccttt gattcgaacg
     4261 acttttgctg gtactcctac cgctgtagcg tcgtctggaa catctttcaa cacaacggca
     4321 cctgcaccga ttttggcgtt ttttccgatc gttaccggtc ctaatatctg cgcattcgca
     4381 gagagcatgg ctccttgttt aacagttggg tgtcttttac ccgtttcttt tcctgtgccg
     4441 cctaatgtta cgccatggaa taaaatcaca tcgtcctcga tttctgcggt ttcgccaatg
     4501 acgattccca ttccatggtc gatgaacacg ccagttccaa tcgttgctcc tggatggatc
     4561 tcaacaccag ttaggaaacg ccagaattga gcattgatct tcgccaataa aaagagccgg
     4621 tgctgatata aaaaatgaga gaaacgatgc caaaacaagg catgaaaacc agggtatgtc
     4681 aaaacgatct cagctgtcga acgtgcagcc ggatcgtttc tctttgctgc atcaatcgct
     4741 cgggtaaacc aactcatgac tttccactcc tttcgtaaga attttatgta ggaaatcatc
     4801 ttcttataaa gaaaagaagc gccttttaaa taagtttcct tatcaaaaga cgctttccgc
     4861 gtggttccac ttttcttcat aatcaatgat tatctctgac agctaacgcc tgttatacgt
     4921 tcttggctac tttgtttcct ataaaacagt ttttcctgtt ttctgtgttt cgccaagacc
     4981 actcccagag gcatttcggc aaccattcat tgataccttg caccacccgg tatctctctt
     5041 gtaatgatca gctgcttact tttttctgtt catcgtgttt agttcagtac ttgatttaaa
     5101 tgtgctaatg atttttcacg accaagcaat tcgatcgttt caggcaattc tggaccatgc
     5161 atttgtcctg atacagctac acggattggc atgaaaagat tttttccttt tacgccagtt
     5221 tctttttgaa cagctttgat ggcagctttg acagttggag catctactac ttccatttgt
     5281 tctagctgtg ctttgaatgc gtggagaaca gtaggaactg tttcaccagc aagtacttct
     5341 tttgctgctt cattcaatac aggatgttca ttgaaaaata gcgtagacag atcaacgatt
     5401 tctgcagcat agctcatttg aggttgatac aggctaacga tcttcttcac ccattcgatt
     5461 gtcttttcat ctgggttttc tgctacacgt ccatcagcga ttagataagg cagacacatg
     5521 tcagtaaatg catctagatc cattgctttg atgtaatggt tgtttaccca ttgcagtttt
     5581 ttcgcatcga aagctgcggg tgatttactt aggcgttttg gatcgaacat tttgatcaat
     5641 tcttggtgtt cgaagatttc gtcttcgccc acaggtgacc agcccaataa tgcaataaag
     5701 ttgaacattg catctggtag atagcctaat tcgcgatatt gttcgataaa ttgcaagatt
     5761 gattcgtcac gtttgcttag ttttttacct gtttcactgt tgatgatcaa tgtcatatgt
     5821 ccgaaggttg gtggtgtcca gccaaatgct tcatagatca tcagttgttt tggtgtattg
     5881 gcaatatggt catctccacg taaaacgtga gtgattttca tcaaatgatc atcgaccgca
     5941 acagcaaaat tataagttgg cataccatcg cgtttttgta tgacaaagtc gccaccgata
     6001 ttatcggatt cgaacgaaat agcgcctttc accatatctg taaatgcgta ttctgtattg
     6061 cgaggcacac ggaaacgtac aacagattct agaccttgtg cttctttttc tgcttgttct
     6121 tcaggtgtca agttcgcaca tgttcctgcg taatgaggca tttctcctct tgcgcgttgt
     6181 gcttcccgtt ctgcttctaa ttcttcttct gtgcaatagc atttgtatgc tcgattgcta
     6241 gcaagcagct gatcaatcag cggttgatag atttctttac gttcagattg acggtaaggg
     6301 ccgtattctc caggattttc aggagattca tcccaattca ttcccaacca agcaaggttt
     6361 tccaactggc ttttttcgcc atcttcgata ttacgttttt ggtcagtatc ctcaatacga
     6421 ataataaagt ctccatcatt gtggcgggca aacaaataat tgaataatgc agttcttgca
     6481 tttccaatat gcaggtgccc agttggactt ggtgcatagc gtacgcgtac tttcgtcatt
     6541 ttcttcctct tctttcaaac tagactttga ctaacagcaa aaattccgtc agttacggct
     6601 tctcaaatat catttattta aagccactca gcacaaattt taccttttct aaggtaaata
     6661 gtaaagccaa ctggttgaat ttccttacca gttggctgaa tttctttttt attttgattg
     6721 tttagtcttt ttctctgtct cttttttatt gtcgattcct cgtcctgcat gtgcaggttt
     6781 agcaaagatc atgcgtccag cagctgtttg aagggcactt gttacaacga cttcgatacg
     6841 ttcattcatg taatgctgtc catcttctac gacaaccatc gtgccgtcat caaggtaggc
     6901 tactccttgt tggcgttctg tcccggcttt tactactaga acattcatcg tttcaccagg
     6961 gatgacgact ggttttacgg catttgccaa cgcattgata ttaagaacag gtacattttg
     7021 gaattcagag actttattca agttatagtc attggttaca atgacaccat ctaaaagctt
     7081 agccaatttg atcaatttgc tgtctacttc actgatatct tcaaagtctc catcgtacat
     7141 ttcgacagat ataccctctt ctttttgcaa ggcatttagg atatctaatc cgcgacgacc
     7201 acgcacacgt ttcaaactat cccctgagtc cgcgatgtat tgtagttcgt aaagaacaaa
     7261 attagggatc atcaaggttc cttctaagaa tccagtcttt gtaatatcat aaatccgacc
     7321 gtcaatgatc acgcttgtat ccaagatttt atatttatgg aaattttctc ctgattttcg
     7381 ttctaacagt tgactctcaa cttgactagc tgtttcttgc tcgatttttt tgcttcgtga
     7441 accaaaaact ttcttccatt cttcgattcg tgtcgttccc attctcaatc ccagatagcc
     7501 taagatgatc atcagtaaaa tcggcaatac actattgacg aatggaattt ccatattgta
     7561 aagaggggtc gagatcacaa cacctaaagt caatccgatg atcgcaccga tcgcaccgaa
     7621 gagaagataa gtcaagctga cctcacttag tttttgttct acttgtttga taatagctga
     7681 gatatgtttg gccaacagca aagataataa aaagaaaata agtgcgccta acaggctgtt
     7741 ggtaaatgta ttattcagcc atccgtttga ctgttgaccg attgcctgcc aagctgaggg
     7801 taaaaatgaa atacccaagc ttgcgccgac aatgatcatc agcaaagtaa tgacacgttt
     7861 ttgcatcgtt tttcctccgt ttcgacaatc atttattagt tagcggaaca cacgcttcaa
     7921 cgtttcagcc aaagttgcta ctccaactat ctcgattcct tttggcgctt cccagttacc
     7981 taagttgttt ttaggtaggt atacttttgt gaagccgagt ttttggactt ctttgactcg
     8041 ttgttcaata tgactgacac gtctgatttc tccagtcagt ccaatttcac cgatgaaaca
     8101 ttccgttggc tgtgttcctt tttctttata gcttgaagca atactgacag cgatagctaa
     8161 atcaatcgct ggttcattta attttacccc acctgcagct tttaagtaag catcttgatt
     8221 ctgaagaagc aacccagctc ttttttccag cactgccatg atcagagata cccgattgaa
     8281 atcaagacct gttgttgttc gtttggcatt tccgaacata gtaggtgtga ctaatgcttg
     8341 gatctctacc aaaattggac gtgtcccttc cattgccaca acgatagcag agccagttgc
     8401 accgtctagg cgttcttcta agaaaatctg tgaaggatta gcgacttctt ccaatccatg
     8461 ctcatgcatt tcaaaaatcc caatctcatt cgttgagcca aatcggtttt ttactgctcg
     8521 caaaatccga aaactatgat gttgttcacc ttcaaaatat aacaccgtat ccaccatatg
     8581 ttctaacatt cttgggccgg cgatcgagcc ttctttggta acatgaccga cgataaaaat
     8641 ggctatccca tttgttttag cgattttgag tagttctgca gtggtttctc ttacttggct
     8701 gacacttcct gccacacttg tgatgtctgg ctgcgtcatc gtttggatgg aatcaatgat
     8761 aacataatca ggggagatat gttcgatggc acgactgatt tcgttcatat ctgtttcagc
     8821 gtatagataa aattctgtgt tgatacttcc gaggcgttcc gcgcgtaatt ttatctgctc
     8881 tgcgctttct tcgccggata catataagac ttttccgcct atggctgcta attgctgaga
     8941 aacttgtaac agcaaagtgg atttcccgat acctggatcg ccaccaatca agaccataga
     9001 ccctggcacc acacctccgc ctaacacacg gttcagttct tctaattttg ttttgatccg
     9061 aggttctttt ttagggacga cgtctgcgat ttttgttggt tttgcttttt ctcctgtcaa
     9121 acttgtccga gttctgcggt ccgttgtatc ttgttcgatt tcttcgacca tcgtattcca
     9181 ttttccgcaa tttgggcagc gtcccaagaa cttaggcgac acatacccgc aattttggca
     9241 aacaaattgt acttttgatt tttttgccat tgtaccgcct ccttttatcc taatcatgag
     9301 acattaaatc aagcttaagt atctttaacg ttttatttac tggaagaacc aaatccgcct
     9361 tgacgttgag cagtcgtttg atcttgatct gcttttaaaa acggcaaaaa gatcccttgg
     9421 ccgatacgct cgcctttttt gatcactaca tccttgaaac caaagttggt gaattggaac
     9481 atgatatggc cttcatttgc ctcattattg taataatcac tgtcaatcac acctactccg
     9541 tttgtcaaca ctaaaaaccg cttcaacgga ttgcttgaac ggttagcaag ctgcaaaaat
     9601 tcatcttctc ccatgtaagc tttgattcca gtaggcacga gggttggttt caattgtttt
     9661 tcattttctg atacatcttt tttcaatcca tctgcgactg tttccaaccc ctttttccag
     9721 cctgctttcc agatacttgg aatcacgacc tcttctgctg cttcaaaatc atagccagca
     9781 gcatgatgtg tagcgcgctg cggtagattg atattttgat ctttatattt agaaataact
     9841 tcaaatcctc tttttctcac cggttttcct
//
LOCUS       DACGEU010000099         9667 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.101, whole genome shotgun sequence.
ACCESSION   DACGEU010000099 DACGEU010000000
VERSION     DACGEU010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9667)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9667)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9667
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.101"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..650)
                     /locus_tag="IXR40_002400"
     CDS             complement(<1..650)
                     /locus_tag="IXR40_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAQ4362204.1"
                     /translation="MKGDVIVEIKVLFENSRINLNFKSGHGLSLLINYSGKKYLFDAG
                     ANKKLVYNATKMGETLNDLEAVIISHGHSDHTGGLRYLKSGNAPIYTAEGVTLPHYLK
                     ILTTFLYVGIPKNEILKMHENLHTIKTKTELAPSFHIIPLGKANSTTKNLYKKMDDKF
                     VYDDFSDELLVVIEQEDGLIVFTGCSHHGIIDMMEIALETFPTKPIKYLIGGFHMIG"
     gene            975..1391
                     /locus_tag="IXR40_002401"
     CDS             975..1391
                     /locus_tag="IXR40_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HAQ4362205.1"
                     /translation="MATIILASHGEFAQGLKQTATMIIGDSVPIHALSAFRDEDESIL
                     VQIKKLLATIDIEETYILTDILGGSVNNDMLTIIKEYEGLQLITGMNLPLVISIATYN
                     GKIGESELEKLIKESQQSVIDCRKLLVEQLTGGDDL"
     gene            1388..1858
                     /locus_tag="IXR40_002402"
     CDS             1388..1858
                     /locus_tag="IXR40_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016622974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAQ4362206.1"
                     /translation="MIKLVRIDHRLLHGQVVFSWSKSLNINRIIIANKEAANDEFKKM
                     SLNLSKPTGIKLTIFSVEQLLEKMPKIETLNENIMLIFGNTKEIRQFCEAYPKVQEIN
                     YGGIIKKEGSKQFSNAIFLNESEQEDAKKLKALGIKQFIQQVPTSKKEDLNTML"
     gene            1872..2645
                     /locus_tag="IXR40_002403"
     CDS             1872..2645
                     /locus_tag="IXR40_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4362207.1"
                     /translation="MLVQSIGLGLIGVFCILDSRLLGRMNFERPLIVSTLVGLVLGDM
                     EKGLIVGASLELMSLGLVNIGAAAPPDMNMASIIATAFAILSNANAEAALTIAIPISV
                     LGQILGILMRTILSNLTHVADRFIEQGKFSQARRIHILYGSGLYALMYFIPIFLAIYF
                     GTNLVSQIVDAIPEWLTNGLTVASKILPAYGFALLLQTMLTKKMVPFLLLGFLITAYS
                     GLGIIGIAAFACIVAFVMVQVQGKNSNGNQNEPDPLDDL"
     gene            2659..3471
                     /locus_tag="IXR40_002404"
     CDS             2659..3471
                     /locus_tag="IXR40_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAQ4362208.1"
                     /translation="MKEKDQNAWKYRQFLWRSWAIQASWNYERQMNMGFMYGIAPILD
                     NIYKNPEDEAMKKEAYERHMMYYNCTPQTSAFVLGLTASMEEQYYEDQENFNPESISA
                     VKTSLMGPLSGVGDSFFQGTIRVLAFGLGINLAQQGSILGPILAMLISFVPSFLVTYY
                     GGKIGYNMGNKYLSKLYQEGLMDKVMYVCSIVGLMVIGSMIASMIGITTPIQMGKAFV
                     LQDVLDSIMPQFLPLGLTFFMYWLLQKKVKTGWMLAICLVGGIIFSLLGILQ"
     gene            3525..4490
                     /locus_tag="IXR40_002405"
     CDS             3525..4490
                     /locus_tag="IXR40_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAQ4362209.1"
                     /translation="MNSKEIVKEIVAKKEVKSIVFVGCGASKADLYPAKYFLDQNAKQ
                     LRISHYTASEFNYATPASVDESTVVISASLGGTTPETVEANAVAKEKGATVISLTRSI
                     DSPLTKDADYVIYHRFAENYAAKLEKTGYCLELAVELLHQVEGYDHYEAMQEGFATIY
                     DLAQKSAESARKDAKKFAERFKDEKVIYVMSSGATHEVAYSTSICLMMEMQWINSGTF
                     HSGEFFHGPFEIVDKDVPFILLMNDGKTRNIDARALTFLERFDTKTEVVDALDYGLSS
                     HIAKEVLDYFNPFVITAVFRVYAEELSEAREHPLTKRRYMWKLTY"
     gene            4606..7329
                     /locus_tag="IXR40_002406"
     CDS             4606..7329
                     /locus_tag="IXR40_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAQ4362210.1"
                     /translation="MQRLNDYLYQLTLLLKSTPSDNYSARSISQALQLNRSTISSYLN
                     EGVREGLFIKVKSYPVLFLHRTALEELHITLNNSEIESIESLLTISQKPALDQVIGSK
                     GSLKEAIDQIKTAVLYPGKGLPLLLIGASGSGKTFLANKIYEYAVEEKVIHTSAPFID
                     YNCAQYVSNPELLSSALFGYTKGAFTGASQEHTGLLEKADGGVLFLDEVHRLSEEGQE
                     KLFTFMDTGEFSPMGDNSIRKKADVRLVFATTENIYTTFLPTFLRRLPVIVNLPRFQQ
                     RPSFERLSLIDEFFVSESKILAKELSVSDALIHFLMNSDFEGNVGNIKNIIKYACGNA
                     YIHQKSQQTIQVKLLDMPLEYSYKFKEQLNKPRKKRADRIYYPEETRQVQLERNNQLF
                     VQFFDQLLTGFSEVIENNKDIKLFLEEMVTKVTQVMDTLIFQEDYEKEQSLYAILNYH
                     IRQSIDFMRESYGFEQDGNRVVALANYLYVKDNQVIFENSLQEKKTKDQLNEFFANVL
                     ETPYWYAKKILSLLSECLDQPVYEEDIFFITLYFYSLNVTNVKTGIKSIVLAHGYSTA
                     SSMANVANRMLNKNVFQAYDMPLDITLEKIEAKLIQFLGDYRTDSGLILLVDMGSLNQ
                     LGGLLVNHLNGPLLIIDHINTPLLLEVGQQVLNNKSITEIGAEIETSLTFKKQLLLPK
                     KKKKKAIITCCYTGIGSATQIQEILTKCLKDAVRELVIIPYDYKKLLENKNFETPFQL
                     YDVIMIVGTEDPKINQIPYIGLDRLINGEAIGEFVHYLEKELTIEVNDLQKELIFNFS
                     ISKIVENLTILDPDKVLSFVQKAIKELSKLLNFDFSNNQLFLLYLHCSCMIERIVRKE
                     SVDEQEDIEEYMQANGEIMDKIHSAFFEIEREYTIEIPDLELRLLSDIVQG"
     gene            7342..7974
                     /locus_tag="IXR40_002407"
     CDS             7342..7974
                     /locus_tag="IXR40_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAQ4362211.1"
                     /translation="MTMGVIFDMDGVLIDSETFYFERRMNFFQELEIDPGSNQIDDYV
                     GKTEAAIWETLVPEDKSLREELYPKYVDYRKTHPIDFAKDLRKEVKPLLDFLKKRDIP
                     LALASSSPVVEIESMLIQCELTEYFSFVISGESLKQSKPHPEIYLKAKQQLDCDFFIA
                     VEDSTIGIKSAKAANIYTVALKQPMQIDQSEADIQIESLQELEQIVLEKG"
     gene            8873..>9667
                     /locus_tag="IXR40_002408"
     CDS             8873..>9667
                     /locus_tag="IXR40_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAQ4362212.1"
                     /translation="MKNLQLKFIVDPSIVRWFRIINQFERNQLATKGELAKSNHVSER
                     TIQTDVNKMKDYFSESVQFVSTKSGYSFQKERPVLFLKQKEQLLENEILFELLGNVFY
                     GELEDMTELIDRFHLSEATFRRYLKQIQPVLEEYGLELSLYPLDLKGEEANIRKFFKD
                     FYYEGEMTPHTLVPPRDLHELVQATFYDKFEYFSIGTGTSPAEFYYSLYIAIERVRQG
                     KTIAIPQGLIERVIASENFRLMYSLKEAIQTNYQVALSEEEFCWLYL"
BASE COUNT         3261 a         1477 c         1884 g         3045 t
ORIGIN      
        1 ccaatcatat ggaagccacc gattaggtat tttatgggtt tagtcggaaa tgtttcaaga
       61 gcaatttcca tcatatcgat aatgccatga tgactacagc cagtaaagac aatcagaccg
      121 tcttcttgct caattacgac caataattca tctgaaaaat catcataaac aaatttatca
      181 tccatctttt tgtataaatt cttggtggtc gagtttgctt tgcctagggg gatgatatgg
      241 aagctcggag caagttctgt tttcgttttt attgtatgta aattctcatg cattttaagg
      301 atttcatttt taggaatacc aacatacaga aacgtggtta aaatctttaa ataatggggt
      361 aaagttacac cttcagctgt ataaataggg gcgtttcctg attttaaata tcttaacccg
      421 ccggtgtggt cagaatgacc gtgtgaaata atcactgcct ccagatcatt caaagtttcc
      481 cccattttag tcgcattata gactaatttt ttattagcgc cagcatcgaa gagatatttc
      541 ttccctgagt agttaattaa gagagataac ccatgtccac ttttaaagtt caaatttatt
      601 cttgagtttt caaataaaac cttgatttcc actataacat ctcctttcac atgaacgtgt
      661 attcatatat tgtagcacat taagttctat tttttgttgt aattaccgaa aaaaatatta
      721 atggacgctt tttacgcttt atttcgtatg tggaagaaaa tttcttagga tgtggcgggg
      781 gattggggca aagctaaatt ccaattacag tgatcattta attagacacc tttaaatacc
      841 cacactttca tcaacactat aatttaggga aagaaaagtg ttggcatgat atagaaaaac
      901 ctttaattaa cagcgtttcc taaaattggc acgcatcttg cttatagaaa agcgtaagga
      961 taggaggaat gaaaatggca actataattc ttgccagcca tggggaattt gctcaaggat
     1021 taaagcaaac agctacaatg attattggag atagtgtacc aattcatgcc ttgtcagcat
     1081 ttagagatga agatgaatct attttggtac aaataaaaaa acttttagcc acaatagata
     1141 tagaagaaac ctacatttta actgatattc taggtggtag tgtgaataat gatatgctca
     1201 ctattattaa agagtatgag ggattgcaat taattactgg aatgaactta cctttagtta
     1261 tttctattgc aacctataat ggaaaaattg gggaaagtga gctagaaaag cttattaaag
     1321 agagtcaaca atcagtgatt gattgtagaa aattattagt agaacaactt actggaggag
     1381 atgacctatg attaagttag tacgtattga ccatcgtttg ttgcacggac aggtagtatt
     1441 ttcttggagt aaatcattaa atatcaatcg tattattatt gccaataaag aggcagcgaa
     1501 tgatgaattc aaaaaaatgt ctttgaattt atctaaaccg actggcatta aattaacaat
     1561 tttttcagtt gaacagttac tagaaaaaat gcctaaaatc gaaacactta acgaaaatat
     1621 catgcttatt tttggtaata caaaagaaat tcgtcaattt tgtgaagcct atcctaaagt
     1681 acaagaaatc aactatggag ggataatcaa aaaagaaggt tccaagcaat ttagtaatgc
     1741 cattttcttg aatgaatctg agcaagaaga tgccaaaaaa ttaaaagctc ttggcattaa
     1801 acaatttatt caacaggtac caacttctaa aaaagaagat ttgaatacaa tgttataaag
     1861 gaggaatgaa aatgctcgtt cagtcaattg gtttagggtt aatcggtgtt ttttgtattt
     1921 tagactcaag gcttttagga agaatgaatt ttgaacgacc gttgattgtc agtacgcttg
     1981 ttggtttggt acttggagac atggaaaaag gattaattgt tggagcctct ttggaattga
     2041 tgtccttagg attagtaaat atcggagctg ctgcaccacc tgatatgaat atggcatcaa
     2101 ttattgctac agcctttgcc attttatcaa atgcgaatgc agaagcagca ttaacgattg
     2161 ccattccaat ttcagtgtta ggtcaaatac taggtatctt aatgcggacg attttgtcaa
     2221 atttgactca cgttgcggat cgctttatcg aacaagggaa atttagccaa gcaaggagaa
     2281 ttcatatact ttatggctcg ggattatatg ctctcatgta ttttattcct atttttctag
     2341 caatttattt tggaacgaat cttgtttctc agattgttga tgcgattcct gagtggctaa
     2401 caaatggctt aacggttgca agtaaaattt taccagcata tgggtttgcg ttgttattac
     2461 aaacgatgtt aacgaaaaaa atggtgccat ttttattact tggattttta attactgctt
     2521 attctggatt gggaatcatt ggtattgcag ccttcgcatg tattgttgcg tttgtcatgg
     2581 ttcaagttca aggtaaaaac tcaaatggta accaaaatga gccagatcca ttagatgact
     2641 tataaggagg tagattaagt gaaagagaaa gatcaaaatg catggaaata tcggcagttc
     2701 ttatggcgtt catgggcaat tcaagcctca tggaactatg aacgacaaat gaacatgggt
     2761 tttatgtacg gaattgcacc aattctagat aacatttaca agaatccaga agatgaagca
     2821 atgaagaaag aagcttacga gcggcatatg atgtactaca actgtacccc tcaaacaagt
     2881 gcatttgtgt tagggttaac tgcttctatg gaggagcaat actacgaaga ccaagaaaac
     2941 tttaatccgg aatcaatcag tgcagtgaag acttctctga tgggaccgct atctggtgtt
     3001 ggtgattctt tctttcaagg aacgattcgg gtattagcct ttggactagg aattaattta
     3061 gcccaacaag gtagtatttt aggtccaatt ctagcaatgt taatttcctt tgtaccttcc
     3121 tttttagtta cttactatgg tgggaaaatt ggctataaca tggggaataa atacttgtct
     3181 aaactgtatc aagaaggttt gatggataaa gtaatgtatg tttgctccat tgtggggttg
     3241 atggtcattg gttcgatgat tgccagcatg atcgggatta caacaccaat tcaaatgggt
     3301 aaagcttttg tcttacaaga tgtattagat agtattatgc cacaattttt accattagga
     3361 ttaaccttct tcatgtactg gttattgcag aaaaaggtca aaacaggatg gatgttggca
     3421 atctgtttag tcggaggaat tatttttagt ttgttaggta tcttacaata agggaataac
     3481 caataaattt ggttgaataa tataaataag gaggaattca attgatgaat tcaaaagaaa
     3541 ttgttaaaga aatcgtagcg aaaaaagagg taaaatcaat cgtatttgtt ggctgtggcg
     3601 cttcaaaagc ggacctttat cctgcaaagt attttctaga ccaaaatgcg aagcagttac
     3661 ggattagtca ttacacagcc agcgaattta actatgcaac accagcatct gtagatgagt
     3721 caactgtcgt tatttcagct tctttaggag gtacgactcc agaaacagtt gaagctaacg
     3781 cagtagctaa agaaaaaggt gctacagtta ttagtctaac acgaagcatt gactcaccgt
     3841 taacaaaaga tgcagattat gtaatttatc atcgatttgc agagaactat gctgctaaat
     3901 tagaaaaaac aggctactgt ttagaattgg cagtagaact tttacatcaa gtagaaggtt
     3961 atgaccatta tgaagcaatg caagaaggat ttgctactat ctatgatctt gcccaaaaaa
     4021 gtgcagaatc agctcgtaaa gatgcgaaga aatttgctga acgctttaaa gatgaaaaag
     4081 ttatttatgt aatgagtagt ggtgctacac atgaagtagc atactcaaca tcaatttgct
     4141 tgatgatgga aatgcaatgg attaattctg gtaccttcca ttcaggagaa tttttccacg
     4201 gaccattcga aattgtggat aaagacgtac cgtttatatt attaatgaat gatggaaaaa
     4261 ctagaaatat agatgctcga gcattaactt tccttgaacg ctttgatacg aaaacagaag
     4321 ttgtagatgc cttggattat ggcttgtctt cacatattgc taaagaagtc ttagactact
     4381 ttaacccatt cgtgattact gcagtattta gagtttatgc agaagaattg tcagaagcaa
     4441 gagaacatcc attaactaag agacgttata tgtggaaact aacttattaa aaaatagatc
     4501 aaactaaata aggtggcttg agaaattaag ccaccttgtt ttcttcaatg tgattttata
     4561 catatggtaa aataactagt acatattgtg aaagcaggtg gcaagatgca gcgattaaat
     4621 gactatcttt atcaactaac attgcttttg aaatctacgc cttcagataa ttattcagct
     4681 cgcagtattt cgcaagcttt acagttgaat agaagtacaa tcagtagcta cttaaatgaa
     4741 ggtgttcgtg aagggctttt cataaaagta aaaagttacc cggttttatt tttacataga
     4801 acagctcttg aagaactaca tatcacactg aataactccg aaatagaatc aattgaaagc
     4861 ttgttaacaa tttctcaaaa acccgcatta gatcaagtaa ttggctctaa aggaagtttg
     4921 aaagaagcaa ttgatcaaat taaaacggca gtcttatatc ctggaaaagg gttgccttta
     4981 ttattgatcg gcgctagtgg atcagggaaa acctttctag cgaataaaat atatgaatat
     5041 gcagtagaag aaaaggtcat tcacacatcg gcacctttca tagattataa ttgtgcacaa
     5101 tatgtgagca atccagagtt actatcctct gctttatttg gctacacgaa aggagcattt
     5161 accggagcaa gccaggagca tactggtttg ctagaaaaag ccgatggagg agtattgttt
     5221 ttagatgaag tgcatcgctt atctgaagaa gggcaagaga aattatttac atttatggat
     5281 acgggtgaat tctctcctat gggggataat agtattcgga aaaaagccga tgttcgatta
     5341 gtctttgcaa caacagaaaa tatatatacg actttcttac caacttttct taggagattg
     5401 ccagttattg ttaatctacc tagatttcaa caacgtccgt cgtttgaacg tctgtcattg
     5461 attgatgaat tttttgtttc tgagagtaaa attttagcta aggaactatc tgtttctgat
     5521 gcattgattc atttcttaat gaatagtgat tttgaaggta acgtggggaa tattaaaaat
     5581 attatcaagt atgcttgcgg aaacgcatat atccaccaga agagtcagca aacaattcaa
     5641 gttaaattat tggatatgcc tttagagtac agttataaat tcaaggagca actaaataaa
     5701 cccagaaaga aaagagcaga tcgaatctac tatccagaag aaacacgaca agtgcaacta
     5761 gaaagaaaca atcagctttt tgttcaattt tttgaccaat tacttactgg attctctgaa
     5821 gtgattgaaa ataacaagga tattaaacta tttttagaag aaatggttac caaggtaaca
     5881 caagtaatgg atacgcttat ttttcaagag gattacgaaa aagagcagtc tttatacgcc
     5941 attctaaact atcatattcg tcaaagtatt gattttatgc gagaaagcta cgggtttgaa
     6001 caagatggta accgggtagt cgctttggcc aactatctat atgtcaagga taatcaagtg
     6061 atttttgaaa atagtcttca agaaaagaaa accaaagatc agcttaacga attttttgct
     6121 aatgttcttg aaacccctta ttggtatgca aaaaaaatct taagcctttt atctgagtgt
     6181 ttagatcaac ctgtgtatga agaggacatt ttctttatta cgctatattt ttatagtttg
     6241 aatgtcacga atgttaaaac aggtattaag agtattgtgc tagctcatgg ttattctaca
     6301 gctagtagta tggcgaatgt tgccaaccgt atgctgaata agaacgtttt tcaagcttat
     6361 gatatgcctt tagatattac attagagaaa attgaagcaa aattgattca attccttgga
     6421 gattatcgaa cagattcagg cttgatttta ttggtagata tgggttcact aaaccaacta
     6481 ggcggtttat tagtgaatca tctaaatgga ccactgttaa tcattgatca tatcaataca
     6541 ccgttattat tggaagtcgg ccaacaagta ttaaacaata aaagtatcac cgaaatagga
     6601 gcagaaattg aaacaagtct tactttcaaa aagcagttac tacttcccaa gaaaaagaaa
     6661 aagaaagcca tcattacttg ttgttataca gggattggta gtgcgaccca gattcaggag
     6721 attttaacga aatgcttgaa agatgcagtt agagaattag taattattcc gtatgattac
     6781 aaaaagctgt tagaaaacaa gaattttgag actccttttc aattatacga tgtcatcatg
     6841 attgtaggta cagaagatcc caaaattaat cagattccat atattggatt agatcgcctg
     6901 attaatgggg aagcaattgg cgaatttgtt cattacttgg aaaaagagct gactattgaa
     6961 gtgaacgatt tacaaaaaga attaattttc aatttttcaa ttagtaaaat tgtcgaaaat
     7021 ttaaccattt tggatccaga taaggtgcta tcttttgtac aaaaagcaat taaagaatta
     7081 tcgaagttat taaattttga tttttctaat aatcagctgt ttttgttgta ccttcactgt
     7141 agttgtatga ttgaacgaat tgtacgtaaa gaaagtgtgg atgagcaaga ggacattgaa
     7201 gaatatatgc aagcaaatgg agaaataatg gataaaattc atagcgcttt ttttgagatt
     7261 gaaagggaat acacaattga aataccagat ttagagttgc gattattgag cgatattgtt
     7321 caaggatagg agtgaattcg aatgacaatg ggagtaattt ttgatatgga tggggtactc
     7381 atagacagcg agacatttta ttttgagaga agaatgaact tctttcaaga actggagata
     7441 gatccaggat caaaccagat tgatgattat gtggggaaaa cagaagctgc aatatgggaa
     7501 acattagttc ctgaggacaa atcattaaga gaggaacttt atccgaaata tgtagattat
     7561 cgaaaaacgc atccaattga tttcgctaaa gatttacgaa aagaagtgaa accgttactt
     7621 gacttcctca agaagcggga tataccattg gcactggcat cttcttctcc agttgttgag
     7681 atagagagta tgctcattca atgtgaactt actgaatatt tttcctttgt tataagtggt
     7741 gagtcattaa aacaaagcaa accacatccc gaaatatatt taaaagcgaa acagcaatta
     7801 gactgtgact tctttattgc agtagaggat tcaacgattg gtattaaatc agcaaaggca
     7861 gcaaatatct atacggtggc actaaaacaa ccaatgcaaa tcgatcagag tgaagcagac
     7921 atacaaattg aaagtctaca agaactggaa caaattgttt tagaaaaagg ttagtgaatt
     7981 aatggaaata aggctatata tctgtgctag ctattttgac taaccaaaaa aacttgctat
     8041 aattcaggtg tagtaaaagg tgctggtaac accttttacg aaaatgcttc ggcagtgata
     8101 atgggattgg ctttttaagt tttttatttt gttcgcaatc cctaaggtca tgtgaatgat
     8161 cctagggatt gctagaatat tttgcaacat tctatctatt tcagaacgta accttcccca
     8221 gttcattggg attcattagc atacaaccaa catttcaaaa agaaattgca ctacaccatt
     8281 attagctatt ttgactaacc ccaaaaaact tgctataatt caggtgtagg taaaaggtgc
     8341 tggtatcacc ttttacgaaa ctgcttcggc agtggtaatg agtgtggctt aaaggactag
     8401 tcctttaagc tttttacttt gttcgcaatc tctaagatca agttaatgat cgataagatt
     8461 gctagaatat tttgcaacat tctatttcag aacgtaacct ttcccattcc actgtgattc
     8521 attggcaacc ctcctcacaa ccaacgtttc aaaagaaatt gtaaagttgt tggggtacca
     8581 cgaccgaaca atactacacc tgaatgatag taagttgtct cattaagtat agcatatcct
     8641 ctttttgggt aaatagaaat cggttacatt ttttatccaa gaccaagttt tttcatttgg
     8701 tcttatttgc tatacccaaa caattccgca gtatagtcga cggtattgat tttatcaggt
     8761 gagtaataga aacttgtttt ccttccccaa aacattacct ataaaggaga aaaaatggta
     8821 tcgtaattat ataggtatag gatgaaattt ttttctaaga ggagggttgt tgatgaaaaa
     8881 tttacagtta aaatttattg ttgatccatc gattgtacgc tggtttcgga ttatcaatca
     8941 atttgagcgc aatcaacttg ccacaaaagg agaattagca aagagtaatc atgtatctga
     9001 acgaaccatt caaacagatg tcaataaaat gaaggactac ttttctgaaa gtgttcaatt
     9061 tgtttcaacg aaaagtgggt attcttttca gaaggaaaga ccggttcttt ttctcaagca
     9121 gaaggagcaa ctactggaga acgaaatttt atttgagttg ttagggaatg tcttttatgg
     9181 cgaattggaa gatatgacgg agctaattga tcgttttcat ttatctgaag cgacttttcg
     9241 tcggtatttg aagcagattc aaccagtttt ggaagaatac ggcttagaat tgagtcttta
     9301 tcctcttgat ttaaaaggag aagaggcaaa tattcgcaag ttttttaaag acttctatta
     9361 tgaaggggag atgacgcccc atactcttgt tccaccaagg gatcttcatg aacttgtgca
     9421 agctacattc tatgataaat ttgagtattt ctcgattgga acagggactt ctcctgctga
     9481 attttattat agtttgtata ttgcgattga gcgtgtgaga caaggaaaaa cgatagccat
     9541 tcctcaaggt ctgattgagc gagtaattgc tagtgagaat tttcgcttaa tgtattcctt
     9601 gaaagaagcg attcaaacaa attatcaagt tgctttatca gaagaggagt tttgttggtt
     9661 gtattta
//
LOCUS       DACGEU010000100         9648 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.102, whole genome shotgun sequence.
ACCESSION   DACGEU010000100 DACGEU010000000
VERSION     DACGEU010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9648)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9648)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9648
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.102"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            5..2377
                     /locus_tag="IXR40_002409"
     CDS             5..2377
                     /locus_tag="IXR40_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362213.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNEQIEKMFEHQKMTNGQ
                     PMNDKRNGRSWFNQQERIENKVQSLREEIKQQEEYVEKLERQEELKEMGYNKYGGLDM
                     TIDNIPRIKEEIERFEKGESAFSAATIRKYQRKLETLEQLKEKSEKGKENILPEVQAI
                     IDSGRVTQWKKNPTIYFLKGYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     RPTDSMKEKENDHFYRVEFNENDPEKGLKSYGGEIVTFELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNQPIYLELAKLCEQVPEKEQKQSVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DKKGQSELQAGIQAVANNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYI
                     AAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQE
                     HKNTLETPENKNIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGK
                     SYGKEIQTALPSEEFALGNPFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            2438..3898
                     /locus_tag="IXR40_002410"
     CDS             2438..3898
                     /locus_tag="IXR40_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HAQ4362214.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDPKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKYERQNF
                     LVRDDRLDHAVAFLWKDPQTKETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFN
                     LKIGDPKQIKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRK
                     KQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVRCERGIANDWQVPKEYKII
                     YEEVAKEEKVTPEAIMAIHKTENNLQLTNQLVSAHKVNAFFGQQLSVNDSIEAINLKD
                     ICREVAKELKVCERVDGTYDFDRFYQEKGDINAQILFSYKAEQYYKGYKNHEHEFVPE
                     VKKDWNDQLKHEIQQQEIRKQKRAMLFQQGRQQERE"
     gene            3909..6113
                     /gene="topB"
                     /locus_tag="IXR40_002411"
     CDS             3909..6113
                     /gene="topB"
                     /locus_tag="IXR40_002411"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAQ4362215.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFPGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFKVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQVGADQGKTFKRLWINSLEKEAIYQGFQQLRDAKETYP
                     KFEEAQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FKKEPYFEGKSEVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGMIRQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLRAEEISTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTEATYES
                     LTPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAIGKVPIDLGWKKLFGK
                     ESDGKEKEEEPLLPKVTKGEMVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGVLLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGERKGTQTTFLANIQKFVSHLLEVVPGQIQSIDFGSTLQEVKA
                     ASEKQEAARHLGICPKCQEQEVLLYQKVAACTSEACDFKLWTTIAKKKLTATQLKEII
                     QNSRTSQPVKGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNFKKRTRRTTK"
     gene            6353..6946
                     /locus_tag="IXR40_002412"
     CDS             6353..6946
                     /locus_tag="IXR40_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection protein"
                     /protein_id="HAQ4362216.1"
                     /translation="MQEKLKELLAIRDGNLSMKEARKLGIAATTVQRLVNQGKLIKVD
                     RGYYVEDGHGIDDLFWLQQRFSRGIFSHETTLDIYQLSTNMPKFIHLTFPHGYNVDRS
                     ITKEQQLQFHFVKKEVYELGKVEGTSFQGNPITMYDKERTLCDIWNPRYEIEYEMKLE
                     ALKEYMEDPLRDPSKLRDYMTKLHVEKEMKYHMQSLY"
     gene            6959..7858
                     /locus_tag="IXR40_002413"
     CDS             6959..7858
                     /locus_tag="IXR40_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HAQ4362217.1"
                     /translation="MTPTQFAAKTRNLAKRTGLNAQLVQRHFMMDRLIEQISESKYKN
                     DFILKGGFLLGSKYGIDRRTTIDIDTTFRNSKLTEEKLKSIFNDLTRKPTKEGIVFSI
                     QGMKETREADFYPGFQIKLVANLEKVRVPFKMDVTTGDSIYPEVDTHYHQLMFEDKKV
                     EIPAYPTAQIIAEKLSATFSFGTDNSRAKDYYDLFTIPKLENIDTKELYKSVRNTFTK
                     RGDTKPLSFYYEREMDKIIGNDYLEKQWEKYRSVNTFANSISFTDTVNEIDHLMKSVI
                     KIENQERKRQFKRSQQMNQEMER"
     gene            7861..8358
                     /gene="ssb"
                     /locus_tag="IXR40_002414"
     CDS             7861..8358
                     /gene="ssb"
                     /locus_tag="IXR40_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HAQ4362218.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGNR
                     EADFINCVIWRKPAETMVTLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRAHADQSSTSPSTTTFEQRDTATPNNNGLNALQNPFGNPFGGQSIDISD
                     DDLPF"
     gene            8724..8984
                     /locus_tag="IXR40_002415"
     CDS             8724..8984
                     /locus_tag="IXR40_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362219.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIASMYVRNPDHFTRSMGI"
     gene            9429..9635
                     /locus_tag="IXR40_002416"
     CDS             9429..9635
                     /locus_tag="IXR40_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HAQ4362220.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGQRAKCIKSYRLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
BASE COUNT         3621 a         1636 c         2031 g         2360 t
ORIGIN      
        1 gaacatggca gaagaaaaag aaccactaga caatagtcgt ttgggaaaat ccaaaagaaa
       61 actagtacga ttgcaaaatg aattaaacga acaaattgaa aagatgtttg aacaccaaaa
      121 aatgacgaac ggtcaaccaa tgaacgacaa gaggaatggc cgttcatggt ttaaccagca
      181 agaacgaatc gaaaataaag tccaaagtct gagagaagag atcaagcaac aagaagaata
      241 cgtggaaaag cttgaaagac aagaagagct aaaggaaatg ggctataaca agtacggcgg
      301 actggatatg acgatcgata atattccaag aatcaaagaa gaaatcgaac gctttgaaaa
      361 aggtgaatcg gctttttcag ccgccacgat ccgaaaatac caacggaagt tggaaacatt
      421 agaacagctg aaagaaaaat cagaaaaagg aaaagaaaat atcctccctg aagtacaagc
      481 gatcattgac agcggacgag tgacgcaatg gaaaaaaaat ccaaccattt attttttgaa
      541 aggctatcga aaagttgctt tagaactgaa tgaaaacggg ggatttgagg aatcaaaaaa
      601 ataccaagcc acgtcggaag aggaaaaagc agctgttcgt gaattacttg aagaggctag
      661 accaactgat tctatgaagg agaaagaaaa cgatcatttc tatcgagtag aattcaacga
      721 aaatgatcca gaaaaaggat tgaaaagtta tggtggggag atcgtaacat tcgaattgat
      781 cgatcaactc aaaacattgg ataaccaata cgccgcagaa gcaggttatt ataaattcta
      841 ttttgaggaa gtgaagaacg gagaagtagt cgatcagatc cgaatggatc taggggatgg
      901 cgtcaacagt aatcaaccaa tctatttaga gttagcaaaa ttgtgcgaac aagtacctga
      961 gaaggaacaa aaacaatcgg tcaaaaatga acctgtttcg aaagaacaaa tgcagtcgaa
     1021 agaaacaaaa acaaaacaaa agggctatca aaaacgaacg gcagaagaga ttaaacaaga
     1081 agttaaatcc ctttcgcaac aggcactgga tgcggtgaaa aagcataccc attctcctga
     1141 agacgtcaaa gaacttttga actttatgtc tcgttttcca gaacgatcct ttagaaatca
     1201 attattgatt gaggaacaat ttccaggtgc aacggcttgt ttaggtcgtg ccgcgttgaa
     1261 aaaagaagga atctatatca aaaaagggga acaagggaac aagatctttg tcagaaaaac
     1321 ggtcaaaggg ttttatgaga aaggacgtgg ctttgttcga gaaacagaag ctacaccaga
     1381 agataaaaaa cgaatcgaaa gtggtcaaat cgaagtgatc aaaaaacctt actatacgat
     1441 tgaaaaagtg tttgatatca cacaaacaca gttaaaacct gaagactatc cgaaaatctt
     1501 tccgaaccgt gtctttgatt ttcaattgga taaaaaagga cagtcagaac ttcaagctgg
     1561 gattcaagcg gtagccaaca atattggaat acaaattcga gatatgacag aaagtgaagt
     1621 ctatcaaaga gaattaggac aagcacgtgg ggcgtatgtt cgtaacgaat ttactggcga
     1681 agaagaaatc gtcatgaata ctcgaaatac tcctacgcag catttagcta caagtattca
     1741 tgaattagcc catgcaagaa tgcacaaatt ttcagaatta gataccgcaa ctaaagaatt
     1801 gcaggcagaa atgacttctt atattgtgtg caaacatttt ggaatggaca cgtcggagaa
     1861 agctattcct tatattgcag catggacgaa gaatggtcag acgttggatg ataaggaagc
     1921 tgcggaacgt gggaaaatca tgaatgatgt cagccgtgtc gcaaatgaat tcattcaaac
     1981 catttctaat gaaatcaatc aatacagaga aagagaacca gagatccaac cagcagaagt
     2041 gaagcaggag cataaaaata ctttagaaac gccagagaat aagaatattg tgcccgttgg
     2101 ttcactttgg atcgacaaga aagacgggaa agtaatggaa gaagatacgg gtcgaacgtt
     2161 acatttgaag gatgcggcgt ttattgaaga tccgcagcat aatcaagtaa ttttaaaagg
     2221 aaaaagttat ggaaaagaga tccaaacggc gttaccttca gaagaatttg cgctaggaaa
     2281 tccattccga ttttcacttg agacagtgtc agaagtggca aaacgaaaaa atgaaatcta
     2341 ttatgaacaa caattgtcac aaaaagaacg tgtataaaac aagtaaaaaa gactatctga
     2401 aaaacggata gtcttttttc ttttgggagg ttttaaaatg accgagaaaa aaatgagtct
     2461 tattgatcga tgtaaacaga tcgatatagt ggattttgct cgaaacaatg gaatggctgt
     2521 agtcaataaa ggacgagatt atcgcttaga agaccatgat tcatttgttt ttgatcgaag
     2581 aaaacaacgt ttttattgga acagtcaaaa tattagtggc gacattattg aattagctaa
     2641 actttttttc atagacaaag agatccaaga ccctaagcaa caatttaaag cagccactga
     2701 ttttattcta aagaatgaag acaaaacaga acgagtggaa aatcttcatt ttgaaacaga
     2761 aaagtacaaa gatcaccccg ttgattatca accactcaca gaaaaaggaa ggaattatct
     2821 gaaggaagaa cgaaaactac cagagtggct gattgattat gcagaaaaag aagggttgat
     2881 tgccgaacta aagccaaaat atgaacggca aaatttctta gttcgagacg atcgtttaga
     2941 tcatgcggtc gcctttttat ggaaagatcc acagacaaaa gagacagtag gggcgagtta
     3001 tcaaggaacg ttcattgatt atgaacgttt tggtgagaga ggcacatata agcatataga
     3061 taaaaattcg acagcgaatc atggctttaa cctaaagatc ggtgacccta agcagataaa
     3121 attttttgag agtagtattg atttacttag ctatgctgca ctgaatcgtg atcagttaaa
     3181 cgatacgtgg ttagtctcta tggaagggtt aaaacaccat gtgatcagtc attattttgg
     3241 tgaggcagta tctgaattga gaaagaaaca agcctttcct caatccatcg agatttgtgt
     3301 ggataatgac cgtgcaggac atattttcta cgaaaaagaa caattaatgg gcgcagtcga
     3361 tccatttacg aatcagaaag tacgttgtga acgaggaatc gctaatgatt ggcaagtgcc
     3421 aaaagaatac aaaatcattt atgaagaagt cgcaaaagaa gaaaaggtca caccagaagc
     3481 tattatggcc atacacaaga cagaaaacaa tctgcaatta acgaaccaac tggtttccgc
     3541 tcacaaagta aatgcgtttt ttggccagca gctttctgtt aacgattcaa tagaagccat
     3601 taatttgaaa gatatttgta gagaagtcgc aaaagaatta aaagtttgtg aacgcgtgga
     3661 tggtacgtac gattttgatc gtttttatca agaaaaaggg gatattaatg cgcagattct
     3721 tttctcttat aaagcagaac aatactacaa aggctataaa aatcatgaac atgaatttgt
     3781 acctgaagta aaaaaggact ggaacgatca attgaagcat gagatccagc aacaagaaat
     3841 cagaaagcaa aaacgtgcca tgttgtttca acaaggcaga caacaagaaa gggagtgaaa
     3901 tcgtcatgat gaaaaccgtt attttagcag aaaagccgtc acaagcgaaa gcttatgccg
     3961 atagcttctc taaagccact cgaaaagacg ggtattttga aatccaagat cgattgtttc
     4021 ctggtgaaac tgtgatcacg tatggttttg gtcatttagt cgaattagat tcgcccgata
     4081 tgtacgatga aaattggaaa caatggtcat tagaacattt gcctattttc cctacacatt
     4141 atcactatca tgttcctaaa gataagaaaa agcaattcaa ggtggtgaaa cagcaacttc
     4201 aatcggccga caccattatt attgcgacag atagcgatcg tgaaggggaa ctgatcgctt
     4261 ggacgatcat tcaacaagta ggcgccgatc aaggaaaaac ctttaaaaga ctttggatca
     4321 actccttaga aaaagaagcc atttatcagg gattccagca gttacgagac gcaaaagaga
     4381 cctatccaaa atttgaagaa gcacaagcac gtcagatcgc cgattggtta attgggatga
     4441 acggtagccc actgtatagt ttactcttgc agcaaaaagg cataccagga agcttttcct
     4501 taggcagagt ccaaacccca acgctttaca tgatttatca attgcaggaa aagattagaa
     4561 atttcaagaa agaaccttat tttgaaggaa aatccgaagt aatcgctcaa aatggcgcat
     4621 ttgatgcgaa gcttgatccg aatgaaaccc aagcgacgca agaagcattt gaagattatt
     4681 taaaagaaaa gggggttcaa ttgggaaaac agccaggcat gattcgccaa gttgaaaccg
     4741 agaaaaaaag cgcggcaagt ccacgtcttt tttctctatc cagccttcag tctaaaatga
     4801 atcagctcat gaaagctagt gccaaagaca ctttggaagc catgcaaggc ttgtatgaag
     4861 ggaaatatct aagctatccg cgaacggata ccccttacat tacggaaggg gaatatgcgt
     4921 atctgttgga tcacttagac gaatacaagc attttttgag ggctgaagaa atttcgactc
     4981 ctattcatac accgaatagt aggtacgtga acaacaagaa agtccaggaa cattacgcaa
     5041 tcattcctac aaaaacagtt atgacagaag cgacgtatga aagtctgaca cctttacaac
     5101 aagcgattta cgagcaagtt ttaaaaacga cagtggcgat gtttgcggaa aaatatacct
     5161 atgaagaaac aacgatcttg acgcaagtcc agcagcttca gttaaaggca atcggaaaag
     5221 taccgataga tctaggttgg aagaagttat ttggcaaaga gagcgacgga aaagagaagg
     5281 aagaagagcc gctacttcct aaagtgacaa aaggagaaat ggtgacggta gatctacaag
     5341 tccttgaaaa agaaaccaag ccaccacaac cttataccga aggtacgttg atcactgcga
     5401 tgaaaacagc tgggaaaacc gtggatagtg aagaagcgca atccatattg aaagaagtgg
     5461 aaggaatcgg tacagaagcg acacgggcga atattattga aaccttgaaa caaaaggaat
     5521 atatcaaggt agagaaaaat aagcttgtgg tgacgaataa aggggttttg ctttgccaag
     5581 ctgtggaaaa agagccgctg cttacgagtg ccgaaatgac cgccaaatgg gaaagctact
     5641 tgttaaagat tggagaacga aaaggaacac aaaccacttt tctagccaat atccaaaagt
     5701 ttgtctctca cttattggaa gtcgtcccag gacaaatcca atccattgat tttggatcga
     5761 cgttacaaga agtgaaagca gccagtgaaa agcaagaagc cgcgcgtcat ttaggaattt
     5821 gtccaaaatg ccaggaacaa gaagtcttac tctatcaaaa ggtggcagct tgtacgtctg
     5881 aagcctgtga ttttaaatta tggacaacga ttgccaaaaa gaaactcaca gcgacacagc
     5941 tgaaggagat tattcaaaat agccgaacaa gccaaccagt gaaagggtta aaaggtcaga
     6001 agggttcgtt tgaagcaacg attgttttaa aagaagactt cactacaggc tttgaatttt
     6061 ctgaaaagaa aaaaacgaac ttcaagaaaa gaacacgacg cacgacaaaa taatggaggg
     6121 ttaatcttat gcgtaataca acacacaaac aacaagaaat cgaaaatcaa aaagccaaaa
     6181 ttcgttcaga acaagagaaa ttacgtgcca gtaaaagaag acttcagcaa ttaaagaacc
     6241 agcaacggat tcaaaaagaa atcgaattag atcgatagac attaaccttg ttacaaatac
     6301 actatcatga tatatttaat gtagtgtatt tgtaacaaaa ggggggaagt aaatgcaaga
     6361 gaaactgaaa gaattgttgg ctattcgcga tggaaattta tctatgaagg aagccagaaa
     6421 attaggaatc gcagcaacca ctgtacaaag attggtgaat caaggaaaat tgatcaaagt
     6481 tgatcgtggt tattatgtag aggatggtca tggaatagat gatttatttt ggcttcagca
     6541 acgtttttcc aggggaatct tctctcatga aacgacttta gatatttacc agctttctac
     6601 gaatatgccg aaattcattc acttaacttt tccccatgga tataacgttg atcgttcaat
     6661 tacaaaagag cagcagttac aatttcattt cgtgaagaaa gaagtttatg aactaggaaa
     6721 agtagaggga acttcctttc aaggaaatcc tattactatg tatgataaag agcgtacact
     6781 ttgtgatatt tggaatccga gatatgaaat tgaatatgaa atgaaattag aagcattaaa
     6841 agagtacatg gaagacccat tgagagatcc aagtaaatta agagattaca tgacaaaact
     6901 acatgtagaa aaagaaatga aataccacat gcaaagctta tattgatgga ggaaaaagat
     6961 gacaccgaca caatttgcag caaaaacaag aaatttagca aagaggacag gattaaatgc
     7021 acagttagta caacggcatt ttatgatgga tcgtttaatt gaacaaattt ctgaatctaa
     7081 gtataaaaat gatttcattt tgaaaggtgg ctttttatta ggatcaaaat atggaatcga
     7141 tagaaggacg acaattgata tcgacacgac atttagaaat agcaaattaa ctgaagaaaa
     7201 attgaagagt atttttaatg atttaactag gaaacccacg aaagaaggta ttgttttctc
     7261 tattcaagga atgaaggaaa caagagaagc cgatttttat cctggatttc aaattaaatt
     7321 ggtggctaat ttagagaaag tacgtgtgcc atttaaaatg gacgtgacaa caggagattc
     7381 tatttatcct gaagtagata cacactatca ccaattaatg tttgaagata aaaaggtgga
     7441 gattccagct tatccaacag cacaaattat tgcagaaaag ctaagtgcta cgttcagctt
     7501 tggcacagat aattcgagag caaaagatta ctacgactta tttaccattc cgaaactaga
     7561 aaatatcgat acgaaagagt tatacaaaag tgttcgaaat acatttacaa aacgtgggga
     7621 tacaaaaccg ttgtcctttt attatgaaag agaaatggat aagatcatag gaaatgacta
     7681 tttggaaaag cagtgggaaa aatatcgctc agttaacacg tttgcgaatt ccatttcatt
     7741 tacagataca gtcaacgaaa ttgatcacct aatgaaaagt gtgatcaaaa ttgaaaatca
     7801 agaaagaaaa cggcagttta aaagatcaca acaaatgaat caagaaatgg agagataaag
     7861 atgatcaata atgtaacttt agtaggacgc ttaaccaaag atccagattt acgttatacc
     7921 gcgagtggta ctgcagtagc gacttttacc ctagctgtca accgaaattt cacgaatcaa
     7981 aacggcaatc gagaagctga ttttattaac tgtgtgattt ggcgcaaacc agcagaaaca
     8041 atggtgacat tagctaaaaa aggtagcttg attggtgtag ttgggcggat tcaaacgcgg
     8101 acttatgaca accagcaagg acaacgtgtg tatgtgacag aagttgtggc cgataatttc
     8161 caactattag aaagcaaagc agcgacagaa agccgtgcgc acgctgatca atcgtccacc
     8221 agtccaagca ccaccacttt tgaacaacgg gatacagcga cgcctaataa caatggattg
     8281 aacgctttac agaatccatt tgggaatcca tttggtggac aatcaatcga tattagcgat
     8341 gatgatctac cgttctaagt agcattttct attggttgca tttgctacgg tttatgttat
     8401 aatttagtca acaaaaagaa ttttcaatct ataaccaaaa accactagct ggcgggctag
     8461 tggttttctt ttacgtttct attataagaa ttaacgggta ggcttactgt ctttcttggc
     8521 aaatttacaa tcaagccatt tgcagatata gtgcgcggct acttctgcca tgattgcaaa
     8581 aacaaaatca aaaagaattt tcaaacctat aacctcctcc ccttgccaga ttaggccggg
     8641 gtagcagaca gcaagactat tatagcataa ttgaaatatc caaatgattg gatttttgct
     8701 ataattttag cgaggtgatt gtgatgaaca aatatgttgg tttgcttgat aaaatccgag
     8761 taataaaaac gcaaccgtta ttggttcgct ttactttaca aacgattcat gaatcgatta
     8821 attgtgtagt tgcagatatt gaaattatcg ataaattgct aattatggat gatggaaaat
     8881 acaatattgc cgtcacaggt cacttcaata aacgaaatca gctagttatt gctagcatgt
     8941 atgttagaaa tcccgatcat tttacgcgat cgatgggcat ataaaaaaag aagagttgca
     9001 atcctaatgt aggactgcag ctctttttgt tttacataga aacaagaaaa atgaaaaggc
     9061 ctttttagga aggcgcgagc gccttctcaa ttgaaaaacc tctctcactc caaccgccac
     9121 cgccgttcga gaagaaagga agtgaacgtt gcacgttcac taagataaag ggtcttgcaa
     9181 agcaagacaa aatagaaaaa acttcctctc accaaaaggt tcgttcctgt tcgttatctc
     9241 tttattgatt tgccagaccg gcaacaagtt gccttttatc accaaaaagc gacaaggaca
     9301 agggtaaatg gcacgctgcg cgcccttgtc cttgtcgctt ttcgttgatt cattctggcc
     9361 aacaaatcaa taaagaaaga actaacgaaa ggaagtaaaa cctttcctaa gaggaggcag
     9421 aatcaatcat gcgaaagaaa tttgattatt ggggtgttcc cttcagcgaa ttattcccaa
     9481 actatcatgc accacatact gtcgaatgcg attgtggaca aagagcgaaa tgtatcaaaa
     9541 gctatcgttt gtatcaatgt ccaacatgcg gaaaaaaata caccttgtct tatggcgatt
     9601 atattttgat tgatgagaaa ggaaagaaac gctgatgaaa acataaca
//
LOCUS       DACGEU010000101         9459 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.104, whole genome shotgun sequence.
ACCESSION   DACGEU010000101 DACGEU010000000
VERSION     DACGEU010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9459)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9459)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9459
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.104"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            <1..185
                     /locus_tag="IXR40_002417"
     CDS             <1..185
                     /locus_tag="IXR40_002417"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HAQ4362221.1"
                     /translation="GALISFSVENADEVKKFAQIAKENGGTFHEVDMGMPEEEMFSLE
                     VQDLDGNTLEPVWMKM"
     gene            422..964
                     /locus_tag="IXR40_002418"
     CDS             422..964
                     /locus_tag="IXR40_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HAQ4362222.1"
                     /translation="MNTLIAKDVFRLPEMNARLLSTSALLLALDVILYKIAIGPAYFQ
                     ITFGFLSMALMGYLYGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLF
                     LYHKKINLPSVIAAQLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQI
                     MVVYSFIKTLEARKVFKRAV"
     gene            complement(1047..1598)
                     /gene="lepB"
                     /locus_tag="IXR40_002419"
     CDS             complement(1047..1598)
                     /gene="lepB"
                     /locus_tag="IXR40_002419"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HAQ4362223.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(1750..1977)
                     /locus_tag="IXR40_002420"
     CDS             complement(1750..1977)
                     /locus_tag="IXR40_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HAQ4362224.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            complement(1974..2492)
                     /gene="msrA"
                     /locus_tag="IXR40_002421"
     CDS             complement(1974..2492)
                     /gene="msrA"
                     /locus_tag="IXR40_002421"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAQ4362225.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            complement(2512..3225)
                     /locus_tag="IXR40_002422"
     CDS             complement(2512..3225)
                     /locus_tag="IXR40_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HAQ4362226.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            complement(3228..4124)
                     /locus_tag="IXR40_002423"
     CDS             complement(3228..4124)
                     /locus_tag="IXR40_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HAQ4362227.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            complement(4282..5124)
                     /locus_tag="IXR40_002424"
     CDS             complement(4282..5124)
                     /locus_tag="IXR40_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAQ4362228.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            5256..5909
                     /locus_tag="IXR40_002425"
     CDS             5256..5909
                     /locus_tag="IXR40_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HAQ4362229.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            complement(5972..6499)
                     /locus_tag="IXR40_002426"
     CDS             complement(5972..6499)
                     /locus_tag="IXR40_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAQ4362230.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(6519..7466)
                     /locus_tag="IXR40_002427"
     CDS             complement(6519..7466)
                     /locus_tag="IXR40_002427"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HAQ4362231.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            complement(7478..9364)
                     /locus_tag="IXR40_002428"
     CDS             complement(7478..9364)
                     /locus_tag="IXR40_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAQ4362232.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
BASE COUNT         2529 a         1881 c         1650 g         3399 t
ORIGIN      
        1 gtggtgcttt gatttcgttt agtgttgaaa atgcggatga agtaaaaaaa tttgctcaaa
       61 ttgcaaaaga aaatggtggt actttccacg aagtagatat gggaatgcct gaagaagaaa
      121 tgttttcatt agaagtccaa gatctagacg gaaatacatt agaacccgta tggatgaaga
      181 tgtaagcaga taactaatct gacgtttttt ataacaaaaa aacaaaggcg gatgatacga
      241 taagtattct ccgcctctat tttttttatt cgtacaatct cttttttaca gtttataaaa
      301 gcagtcttct cacccttttt ttaattgtta gatgccagtg tatgtaaatc accaatgtgt
      361 catgacacat tggtgatttt atggtatcct tttattatta actgacaaag gagagaatat
      421 tttgaacact ttgattgcaa aagacgtttt tagattgccc gaaatgaatg caagattgtt
      481 gtcgacctct gctcttttat tagcccttga tgtcatctta tacaagatag cgattggtcc
      541 tgcttatttt caaatcacat tcggattttt aagtatggcg cttatgggtt atctatatgg
      601 accgatctgg gctggtttgc ttgaaatgtt gtcgaacact ttaaatttca cgatatttgg
      661 ttcaggaacg tttcaagctg cttttcttat cacggctttc cttggtggat ttattaatgg
      721 cttattttta tatcataaaa agataaacct gccttccgtc atcgctgccc aattattgat
      781 tatgatccca gtcagccttt ttatcaattc ttggctgatg tctgttttgt ttggtgcaga
      841 tttcaaagta atttttctag gtagattcat caggaatatg atccaaatcc ctattcaaat
      901 aatggttgtt tattcattta tcaaaacttt agaggctaga aaagtgttta aacgagctgt
      961 ttgattttac gtactaaggt agtaaactga ttttggatta aacaataaag cgtgcagtct
     1021 caacagactg cacgctttat tgtttctcac tggatccatt ttatttcatc aagtggataa
     1081 tagacaaatc ttgctttacc tagaatatca gttttattga tcgtgccaaa cgaacgacta
     1141 tcttttgaaa ctcttcgatt atctccaagt acaaaataat tatcttccgg aagcttggat
     1201 tgtcccgtta gctcttgtag tgtaaagtcc gtcgtatagg atgcatttgc atgatctgat
     1261 ttcaggtttt tagttagata aggttcctta actactttcc cattgatctt caattgatca
     1321 ttttggtagc tgacattttc tcctggaaga ccgattactc gtttgatata aatcgtgcca
     1381 tctgctaatt gaaaaacaac aatatcaaat cgtctgatct ccgaaaattt ttccatcaca
     1441 accatatcac cttgcttcaa cacgttttcc attgaattgc cttccactgg taccgggatg
     1501 aataaaaatc cccgcaacat gaacgcaagg aatacagaaa caagtaagta tttgaataca
     1561 agccagaagc gattaatata gcgttgtttt tttgtcaatc tctatcaatc catccctctt
     1621 tttttcattc tttctttatt ataagaaaaa tatcaaaaaa atgcgactag atagctgaaa
     1681 taaaaataat tctttcaatt aggctattgg acaaaaaact tttttgatca taaagtacaa
     1741 aactatctct tatatgtcat gattattttc taaatatttt tcccatgctt cgtcaaagat
     1801 atccatggac ggcaaatagt cgacattcag ttccagataa ttagaaattt cttcgtagct
     1861 agagctgtgc ttaggaaatt ggatgtcttt accggcttct gtagcgaaaa cagataaagc
     1921 atcatgtgtg ccaccgcctc gcagtgtcat taaataatga aaaaagcttc gattcaccct
     1981 tcgttcctcc aattttcttc gataaaggca gcccggcgtg catggtttct tttaaaattt
     2041 tcaggatgct ttttataata ctcttgatgg tcttcttctg ctagataaaa tggttgggct
     2101 ggttcgattt ttgtaacgat tggctgttcg aaacgtccac tttcagctaa ctgtttctta
     2161 cttttttcag caatgatccg ctgttcttct gtcaaataaa agatcaccgg gcgataattg
     2221 tcaccgcgat cctcgaattg tccgaaagcg tcagttggat cagtttgctg ccagtaaagt
     2281 tctactaatt gttcatatga aatcaatgtt ggatcataga taatctccac tgcttctgta
     2341 tgtccagtcg tttggctttt tacttgttca taagtcggat ctggtacatg ccctccagta
     2401 tatcctgaca tcactgtatg gataccagga agcgtgtcga aaggctggat catacaccag
     2461 aagcagcctc ctgcaaatat tgctcgttcc attatgattc cccctctaat actactcatc
     2521 cgatgatttt ttattttctt ttgtcttgct ttcagtactg ctggtgctag ttttgttggt
     2581 atttgagttg tttgaagcat cagaggtatc ttttggcaaa tatagactaa accgaatgtc
     2641 atcatttact aagtcgattt tatctgcttt aatatacatc ccgttttgca ttcggaattg
     2701 atccaaccta agcatgatag tcagatcatc tgtattgact tcgatccaat ctggtaattt
     2761 atagtttctc ttgatcatat tcatcacatc tttgattggc aaactcaatg ttccgataga
     2821 aagacttcta gcttttagtt ggacatttcc gttttccatc acatacggat caaaatataa
     2881 atagaaatcg ataggaaaac ctagtacttc gaaagtacca ttgagtagtg cttcattttc
     2941 caaataaaat ttatattcaa tatcactatc tttttgatac tcactaagga aaaagctgat
     3001 gatttgattg actttttctt tatttgaatt gatcgttaag acaggatctc cttgtctttc
     3061 cgtaagagct ggtatttctg ggagttctgg ttcccgatta gcaaaaatac ggctgcctaa
     3121 aaatacggtc gaaccaagta ctaccccaag aaggataagg aaggcgaatt tccagtaatt
     3181 tgttttcttt gttttgtttg aagatacgtc agatcttgtt ttcatgttta ttgatcatcc
     3241 tccttctcta accattggtt ttgtgtctcg atcagctgat ctctcactgc atttgccatc
     3301 aattgataac ctaaattatt tggatggaaa tgatcttctt catagagcac attatttttg
     3361 atgccattta gattttctgt cgtgctagtt gtttgatctg ttccttcttc tgtgacacct
     3421 acttcctgat tcaatccttg ataaagcaaa tcattgattg ggataaagta gcagttcggc
     3481 attttttttg tcaccgtttc tgttcctttg ttccaattgt taacaattgt ctgcatgtca
     3541 gtgatctcag gaaagttcaa ataaaatgga ttgtagatgc ctaaaatgta aataggtgcg
     3601 gttttattga gggatcgaaa ttcttccaat agttctgtga cattttcctg atagtttttc
     3661 agtggctttt taaaggaatt gaccgttaac ccgaataaat tattttggat aactttcatc
     3721 aaatcattac cgccaacagt cagtgtgata aaatcagctg ttttgatatt gtttcgaatt
     3781 tcttcttttg tttttactcg ctttaagatc tggtcacttc gttcaccatt tacaccatag
     3841 ttttctgttt caaccgcggt caaattataa cggtctttta gatcatttgc gacaagggga
     3901 acgaatcctc cttgcttggt ttgatctcct actccttcag tcagcgaatc tccgatagct
     3961 atgtagtgaa gtttttcttt tttatttgga tcttctctca cagtagttac tggtttcatt
     4021 agtgggccag ctttcggtat agaagcagct aaacctgcat agatgatgat cgcaattaat
     4081 aatgggaaca aaacgaggat caaatgtcgt ttcgttaatt tcattttttc acctcttgta
     4141 ttcgattggt tctaatgtta tcaaaaattt tatcaaaaag gtagtcttta tgaaaaaaga
     4201 aaacaattat tttcctaatt ttataaagaa aaagagaata agctgcaagc ctttcaggct
     4261 gagggcttat cctcttttcg actaatctac ataatacatg attgcaaacg cgtctttacc
     4321 agtatgcgta gcgataaccg gattcgtatg cagtacaggg atatgcatgt ccgggaataa
     4381 ttcttgcaaa ccctctttga attcttgcgc caattctttt gcatccgcat gtgaaatacc
     4441 gatttgtcgc acatttggca attctttcag ttcatttttc aaattattaa accatttatc
     4501 gaacgttttc tttcctcgcc ccttagttac agggattaat tcagaatggg cgaaattcat
     4561 caccacgcgt atgttcaaaa cactagacag caaaccagtt gttcggctga ttcttccacc
     4621 ttttaccaag ttatctagtg tggatattcc gatgtataat tttgtattgt cttgtacttt
     4681 tttgacttct tcaaggattt tctctactgt tttaccttct tttgctaatt cagctgctcg
     4741 aattacctga aaagataatc cttggtcagt ggtatcactg tcgataaccg ttactttcgt
     4801 ttttgttaga ttactggctt gtcttgctgc ttctactgtt ccactcaagc cttttgtcat
     4861 atggatcgaa atcacttcac tgccgtcttc tcctagctca tcatacatcg agatgaattc
     4921 tccaattggt ggttggcttg ttttgggcag attttttgct ttcgccatca tttccataaa
     4981 tctttcgccg tctagttggt catcatcggg atatactgtt ccgtcgatca tgatggatag
     5041 cggcatgaca cgaatgccta aagcatcgcg tacatttttt tccatcgtac atgaagaatc
     5101 tgttacgatt tttacatttg tcattatttt ctctctctct ttctttaaca agatgcctta
     5161 ttcatgttaa actacatgta agacaatttc tatttttagt ataacagaca aataatgatt
     5221 tttcattaat tacacctagt aaaggagccg ttttcatgga aaaaacgaaa tttaatcgaa
     5281 cgtatgaaat attaaatgaa gtgtttaatg cagtcaccca tggaattggg actggattga
     5341 gtatcgcggg actagtggtt cttttagtaa aaggtgccca cttgcattcc tccctccata
     5401 ttgtctctta tgctatctat ggatcgatga tgattctttt atttttaacg tctactttgt
     5461 ttcattcatt gatttttaca aaagcaaaaa aggtgttcca agtattcgat catagttcga
     5521 tttttctttt gattgcagga agttatactc ctttttgttt gctgagtatc cgaggatggc
     5581 taggttggac tttatttgta ttaatctggt tgtttgcgat tcttggcatt atatataaag
     5641 cgttgacgtt gcataaacgg gagagagtat caaaagtatc tacgatcatc tatattttta
     5701 tggggtggct ctgtgtcgtg gctgctgttc ctctttatca ctctcttgga atgactggtg
     5761 ttattttgat ggtagcaggc gggctttctt acacgatagg cgcattcttt tatagcttga
     5821 attctatccg ctatatgcat gttgtttggc atttgtttgt tatgttaggt gcaggtttta
     5881 tgtacttctc tgttttattc tttacttaat aaaaaaaata aagctatgga tgggacagct
     5941 ctaaataaca gctagtctat ccatagcttt tttatatcgt caattcgcct gtcccgcttt
     6001 ttacaggatt ctcattacgc tgatacgttt caaattgatg cggataacga tttttttcat
     6061 ccatttctcc ttgactagta ttgatcagtg accaatcaga ccagtcaaca ggtggaaaat
     6121 aagcatctcc atcgaataca tgatggatga ctgtacggta taatatcgta caaaatggca
     6181 gaaattcttg ataaacagct gaccctccag cgatgaaaaa gataccgtct gtttcttttt
     6241 ccagagcaag cacgtcttcc acactatgca tgacatgcac gccttctgct ttataggaag
     6301 aatctctcgt caaaacaatc gtctgacgat tcggcaacgg acggctaccc atcccttcga
     6361 atgtttttcg tcccatcact agtgtatttg cttctgtcat ttgtttgaag aatttcagat
     6421 catttggcaa acgccaagga agacggtctt cttttccaat caatccgttt tcatcctgtg
     6481 cccaaattgc agctaacatt ttctcatcct ttctgattct aaacagcgat aggagctttg
     6541 atcgccggat gtgggtcata tccttctaat tggatatctt ccatctcaaa atcaaatact
     6601 gactgctttt cctgattcaa aactaaagtc ggaaatgcgc gtatttctcg gctcaattgt
     6661 tctttcattt gttcgatatg attgatataa agatgagcat ctcctaatgt gtgaacaaat
     6721 tcgccaaccg ctaaacctgt ttcatgtgca attaggtgag tcagcaacgc ataacttgca
     6781 atgttgaacg gaacgcctag aaacacatcc ccactgcgtt gatacaattg gcagcttagc
     6841 cgtccctctt gaacataaaa ttgaaacatc gtatgacaag gaggcaaagc catgctagga
     6901 acatcttccg gattccatgc agaaacgatc aatcttctag aatcaggagt ctttttgatt
     6961 gcttcgatca cttgtttgat ttgatcgata aagccaccgt cttttgtttc ccagtgacgc
     7021 cattgatagc cgtagatgtg tccaagatcg ccgtatgttt cagcaaagga atcatcggtt
     7081 aggatcttct cgcaaaaaag cttgctctgc tttttatatt cttcattgaa ttcaggatct
     7141 gtcaaacatc tatggccaaa atcagtcata tctggtccat tatagtctgg acttttgatg
     7201 tagcgttcaa atgcccattc atcccaaata tggtttttat tttgtaatag atagcggata
     7261 ttcgtatctc cttttaaaaa ccaaagcaat tcgcttttga tcaatccaaa aggtactcgt
     7321 ttcgttgtta acaaaggaaa ccctttttgc agatcaaacc gcatttggta tccgaataag
     7381 cttaatgtgc ctgtgcctgt tctgtcttct ttacgatgcc cttcttccaa caattttctt
     7441 cctaagtcaa gatacgcttg ttccatcctt tttcctccta atcttctacc cattcactca
     7501 agtattccca ccgtgccatt ttttcttcaa gttgtgcttc tgtttcagat acgtcgtttt
     7561 gcaattcttg taatcgagtg aaattatctc cttgatgatt catctcttct tggagcaatg
     7621 agattttttc ttcaagttct gcaatctcat cttcaatcgt ttcccattct ttttgttcca
     7681 tgtaagataa tttcttcttt tcagcaggtt ccttgctctg tatttttggt ttcgcttttt
     7741 cagcaggctg ctgggtctct ttttgcttca gtaaataact ggacatgttt ccgtaataaa
     7801 gttcttgttt tccgtttcct tggaatacta ataacttatc tgctaccttg tccaagaaat
     7861 aacggtcatg ggaaacagtg atcacagcac ctggaaaact tctaaaataa tcttccaaaa
     7921 tcgtcaatgt tgctatgtcc aaatcattgg tcggttcatc caataataaa acattaggtt
     7981 gctgaatcag cagtttcaac aaaaataacc ggcgtttttc tccgcctgaa agtttgccta
     8041 tcagtgtccc atgcataaat cttggaaata aaaatcgttc aagtaattct gctactccga
     8101 tttgactgcc atctgctgtt tttgcttctt cagcagcttc ttgtaagtaa gcaatcatcc
     8161 gtttatctgg tgccatttct tcattttctt gtgtataata cgcaagatga accgtttcac
     8221 cgatagacat tgtaccgcta tccaggggaa ttctgccagc tagaatatta agcaatgtcg
     8281 attttcccgc accattttta ccagtaatac ctagtctttc ccgagattga atcaataaat
     8341 ctaaatgttc tagcagtgtt tggtcattta tacggtaact gccatctttg atttccagta
     8401 cttttttccc taaacgttgt gtcgctaggt tcagctctaa atcatcttct tggtttactt
     8461 ggtacaagtt ctcctttaga tcttcgaaac ggttgatccg tgcttgctgc ttggtgccac
     8521 gtgcctgtac gccagccctc atccaagcta attcctgttt ataaagccgc ttgcgctttt
     8581 cttcttgttc tacttctaca cgatcacgtt ctgctttttc taagacgtaa gcttcataat
     8641 ttcctttata ctcgtataat tttccaaatg aaagttcgaa gattcggttt gctactctat
     8701 ctagaaaata acgatcgtgg gtaaccatca atagtgcgcc acggtattgt ttcaaatagt
     8761 tttccaacca ctcgatcgct tcataatcta aatggtttgt tggttcgtct agtaatagta
     8821 aatcgggttc atcaatcaac acttgcgcca gactaactcg ttttttctga ccacctgata
     8881 aagtactgat ttttttatct aattcactga ttcctaattt ttgcaaaata atctttgcgt
     8941 tggtatctgt agtccaagca tcttctttat tcatttgttc ttctgcttta gcataacgtt
     9001 tttgcacatc agggtcttct ccgttttccc ctagttcgat caatgcttcc tcatatgctc
     9061 gaacagtttg gatcaagggg ctgtttcctt gaaagactgc ttggagaaca gttaattcat
     9121 cggaaaattc agctgcttga gaaagataac caatacggta atcagttgga taaaacactg
     9181 tttgccgatc accgtcgctg ctatcgatac cggcaataat atttaagaga cttgttttac
     9241 ccgtcccgtt cgtcccaatc aacccgatac ggtctttttc gtggaccaaa aaagaaatct
     9301 ggtcaaacaa atctttttca ccataagttt ttttgaggtc agttactttt aattctttca
     9361 acatgttccc tccttatctt ggatattgta tcataaaaat agtgaacttc aggaaaattt
     9421 ttttggtatt tgttcttttt gtgttctcaa aaaaagaac
//
LOCUS       DACGEU010000102         9442 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.105, whole genome shotgun sequence.
ACCESSION   DACGEU010000102 DACGEU010000000
VERSION     DACGEU010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9442)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9442)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9442
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.105"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            59..205
                     /locus_tag="IXR40_002429"
                     /pseudo
     CDS             59..205
                     /locus_tag="IXR40_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
     gene            282..611
                     /locus_tag="IXR40_002430"
     CDS             282..611
                     /locus_tag="IXR40_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAQ4362233.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            601..888
                     /locus_tag="IXR40_002431"
     CDS             601..888
                     /locus_tag="IXR40_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAQ4362234.1"
                     /translation="MAYEIVPSKHVIKYLKKLKEKPLKEKFLNLIYDEIAIDPYKGEQ
                     KTGDLSGIWSSGFKYAGTTYRVAYEIIENKVIPVLLCGTHENFYEQLKKLI"
     gene            1174..2031
                     /locus_tag="IXR40_002432"
     CDS             1174..2031
                     /locus_tag="IXR40_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAQ4362235.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     DWAIVVLQTQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVDQEMYKQ
                     AQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISILKELEE
                     HENWYVEVE"
     gene            2032..2580
                     /locus_tag="IXR40_002433"
     CDS             2032..2580
                     /locus_tag="IXR40_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362236.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQSRGRTKKVGAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETN
                     MTRDELLRKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTT
                     SQIKQDTEDSLRKGWGMNNKVR"
     gene            2840..3473
                     /locus_tag="IXR40_002434"
                     /pseudo
     CDS             2840..3473
                     /locus_tag="IXR40_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348804.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
     gene            complement(3518..4467)
                     /locus_tag="IXR40_002435"
                     /pseudo
     CDS             complement(3518..4467)
                     /locus_tag="IXR40_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300609.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
     gene            5069..6913
                     /locus_tag="IXR40_002436"
     CDS             5069..6913
                     /locus_tag="IXR40_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4362237.1"
                     /translation="MNYKQTAEEVLQYIGGEENISHLEHCSTRLRFTLKDNSKVNMSQ
                     LEKVDGVMGVRQNVQCQVIIGNDVVEVYDEVKALLGDNVSNTEEAPKQKQKLGSVLLD
                     FIISIFQPLIPAIAGGGVLKSLLLLASILGLISDQSQTYQILNLVGGAPLYFLPILVA
                     MTTANKLKVNQLVAVSAVGALILPEMTAMLAEGATFLSFGLDNIAYASQVFPAILTVL
                     FYAQLEKWFTKVSPKPIRIFFVPMMSLLITVPIALLLLGPLGYNVGTAFSSIIVSLYN
                     QFGWVATGVLAAVLPLMVVTGMHKAMIPYAVSSMSELGAELLYLPASLAHNISEAGAC
                     FAVSIKTKDKKLKSTAVSAGISALFGITEPALYGVTILHKRVLYAVMFSSLIGGAFAG
                     IVALQAFALVGPGIASITMFADKADPMNLVWAFAVSGISFVVAFAAALVLYKDKEVVN
                     EVETKMETAVVSDAVLSSPVNGKVISLSEVKDTVFSSGMVGDGVAIIPEEGILVAPED
                     GEITMVFETKHAIGLKTANGAELLFHIGIDTVQLEGKGFEAFVRSGEKVAKGQKLIAF
                     DIDLIKEAGFDPTVICVVTNKDNYTIRSFNLEKLVTNDSDLLAISPIA"
     gene            6969..8435
                     /locus_tag="IXR40_002437"
     CDS             6969..8435
                     /locus_tag="IXR40_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAQ4362238.1"
                     /translation="MTNTTSFPKGFLWGGAIAANQVEGAWNVDGKGLSVADMATYKPN
                     LDNKDFAAHMHVTLQSIKEASEDKSDKWYPKRRGVDFYHHYKEDLALFAEMGFKTLRL
                     SIAWTRLFPTGEELEPNEKGVAFYENVFKEMQRLGIEPIVTLSHYEMPLALAVKYNGW
                     VERRVIDDFVRFANVCFDRFGKYVKYWLTFNEIDSIHRHPFTTAGIIQEKSAEGQEAQ
                     DIYQALHHQFVASALVTKDAHEKIPGSQVGCMLTKLMTYPLTCAPEDVELTLKKNLEN
                     NFYADVQVKGEYPALIEKDLENRGIQIKMEDEDREILKKHTVDFVSFSYYMSMAESAD
                     PNAERTPGNTVLGVKNPHLPSTDWGWQIDPKGLKISLIELYDRYQVPLMIVENGMGAV
                     DQVVDGKIHDPYRIDYFKAHFQQMKEAIDEGVDLIAYTSWGPIDLVSAGTSQMSKRYG
                     FIYVDADDEGNGTYNRLKKDSFNWYKEVIETNGASLFE"
     gene            8472..9314
                     /locus_tag="IXR40_002438"
     CDS             8472..9314
                     /locus_tag="IXR40_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAQ4362239.1"
                     /translation="MISIKKVLNSSVVLVEENGKEMIALGKGIGFGQKAGDEISGDKV
                     DKIFLPFEEKKSSQLLELVEEIPIEFFEITRTIVFEAEKGLDKKLNPGVYLTLTDHLH
                     FAVERAQKGVNIANRLYWEIKIYYPKEFQIGKYALTLLNEQYGIDLPKEEASNIAFHL
                     INAQSEDPDSGAGFKYAKMIGGIVNLVRYSLQKDIDTNSIHYARFITHVRFFVERYYS
                     DALLDDGEEEFYNQMWILYPSAMESAAKIKDYIEKVYHKTIPNDEVVYLGVHINRLMK
                     HANG"
BASE COUNT         3246 a         1442 c         1906 g         2848 t
ORIGIN      
        1 agcttaaatc atagataccg taagggattt tattctttat ttaaaacttt gcaacagaac
       61 ccaatcattt gagaagttaa aacctacaca tgaaggtagg tattttagaa gattgaatag
      121 acaacaccgg gttgtttata aggtagatga agatgaacac gtggttgaaa tttattcagc
      181 aaggacgcat tacgagtcac agtaattact tgtaaataca ttatctcgtg gtataatgta
      241 tttactaagt aattacatac tgttagaaat gagggattta aatgattaca aaaacaagaa
      301 aacaaggcaa ttcaatcatg ttgacagtac ctaaagattt taatgttcct aatggagtcg
      361 aagttgaagc aaagttggta gagaatggta ttctttatga atttgttgaa ccacaaaaag
      421 aattttatga ttttagcgaa gatattttgt ctgatataat tgcagaaggc tacgataaag
      481 atgagattct tgtagaattt aagaatagaa aaaacaaaat gcattcttcc tttagagata
      541 ttgctgaaga tacacttact aattctaaag taatgactaa agaggagttg gcaacagaaa
      601 ttggcttatg aaatcgttcc ttcaaaacat gtcattaagt atttaaaaaa gctaaaagag
      661 aagccattga aagaaaaatt tttgaattta atttatgatg aaattgcgat tgatccatat
      721 aagggtgaac aaaaaactgg ggatttatca ggtatttggt ctagtgggtt caaatatgcg
      781 ggcacaacat atagagtagc ttacgagatt atagaaaaca aggttattcc agtattgtta
      841 tgtggaacgc atgaaaactt ttatgaacag ttgaaaaaat taatctagtg atttgttgtc
      901 gttcttaaga aggacggctt cttttttatc gaaaatctga ttcgtctaca tgactaaagt
      961 cgcgagtatt ctctgcttct cgataaatta aataacgtca ttactttgag gaaagctata
     1021 aatcaatata tttcagcttt tccttattta tgtactacct tttacttatt aattataagg
     1081 tagtacatat atatcttttt tttggtagta actaaaaata aatatgttat aatagtatca
     1141 aatgaatatt gctaaaagaa aagaggtagg aacgtggtag cgaagaaata tgtaatcggt
     1201 aattttaaag gtggcgtagg taaaagtacg tgcgcgcaaa tgttagggtt tgaatcagca
     1261 gttaatgaag gaaaaagaac cttgataatt gacttggata tgcaaggaaa tacttctgat
     1321 gtgatgaact taacgcatat gaacttcact aacgaagaag gaggcggaga aggtgaaccg
     1381 attgtttacg aaaatactgt gactgacgtg ttgataaaca atcttccacc taaagaggct
     1441 gtctataaag taatcaataa cctctatata cttccagcag acatgtcctt tgaaatgtat
     1501 gatgattgga tcaaagacca atataatgat tcattatccc aattcaaata tatgaaagaa
     1561 aagctagaac cattatttga tgagtttgac gtcatctatt tagatgtccc accttctatt
     1621 tctgtatata gtaaatccgc gatgtacatt gcggattggg caatcgtcgt cttacagacc
     1681 caagtaaaat cgatgagaaa tgcgatgcaa tatcttgagt atatggactt ttttgtgaaa
     1741 gaatttgata caaatttata tgttgctggt gttattcctt tcatgttgga aagcggtgac
     1801 gcagtagatc aggaaatgta taaacaagcc caagagattt atggggaaca tttgattaaa
     1861 aatgttgtac tcaaaaatgc gcgcttaaaa cgatacgacg gatcaggtat tacgatggag
     1921 aagacaaaga aaggtctctt aaaacaatgg gatcgcaaaa gccacgaatt atttatcagt
     1981 attttgaaag aattggaaga acacgagaat tggtatgtgg aggtggagta attggctgac
     2041 atcaaaggac ttgatatttt tgggaacaac aaaggactcg ccaaaataaa aaaagaagca
     2101 gaagcaaaga aaaagcagca agcaattaca ccatctgaaa ataagcaatt agaagtgcac
     2161 caagttcaag aaataaaaac ttcctccaat gttgaaagac agagtagagg aagaacaaaa
     2221 aaagttggcg caccaatcag aaagtttgat aaggtttatt ccaccaagca tcctttaaaa
     2281 ctgtcgactt tgttaaatgc gacttccaga gttttagtag aaaagtatga gactaatatg
     2341 acaagagatg aattgcttag aaaagcttta gatgagtata ttaaacagaa tcttacgcaa
     2401 gaagataaac aagatttgtt taatgacgtg gtgaaagaac tagacttgtt cagagaaaaa
     2461 tatccaattg ttccagaatt agatgatcgt ggagaaataa taagaactac cagtcagata
     2521 aaacaagata ccgaagactc actgcgcaaa gggtggggaa tgaataataa agttagataa
     2581 taatcaaaga agaactaagt aactaccttt aaacggtagt tacttagttc ttctttgatt
     2641 tgcgtgaaat agaggggatt tatttttctg gttacgtgat taaaaaatcc aaaaaatgag
     2701 cataggaacg gttatgattt tagggtgtgt tttaatgaga tattgtgatt tcattaataa
     2761 gtgtatgata atctgttgtt gagttagtaa ataagtaata gagctaactc taaaataaaa
     2821 ctattaggag gagatgtaga tgaaaaagtt taaaaagaaa atatatttag gattggttgt
     2881 tggggtgagt atgtttgggt tcatggctca tactaaacaa gtaactgcag atactaacca
     2941 aaaagaaagg attatgagcc aattagatga ctctcaaata gagtatgtac ccaatgagct
     3001 aattgtcagt ttaaaggcta cacaaagaat ttcaacagag aaaaataaac cgcaaaattt
     3061 attgggtgta aaagttatgg tggaaaaaga tttgactctt aggacaaatg aaagcgatta
     3121 taataagcga gatcaagtat tattagtgaa attgaacgaa gaaattagtg tggaagaggc
     3181 agtaagaaca tttaatgctt ctgatatggt caattatgca gagccaaact atgtggttga
     3241 actagagccg ttgaatgatg ttgaggagcc aaatacaact gattctttag gaaatcgata
     3301 acgatcctaa ttggagtaaa caagctaatt taagagagat tagcatgcca tccgcttggg
     3361 aagaaaccaa gggttctaag gatgtgaagg tagcggtcat tgattcagga attgattatc
     3421 aacatgaaga tctttctgga aatgtagatg aaagtttggg atacgatttt ttttactttt
     3481 ttcaagaaaa taataattca gaatattctg actatattta tgcaacacta gtgactttag
     3541 gagaaacatc aatagccttg ctaaagtttt tgctttcgct aaagagagta ttttcgataa
     3601 tttgtttttt tctaaaatac ctcgttcctc aatatttggg atatggatat gtatagggat
     3661 tcttcgcata aaggtttcca gaaaatcctc tttgccttct gtagtcgcaa aaactaaacg
     3721 tacattggag gcgtgatgga tagtttcacc gactctagaa taagttccgc catccatata
     3781 aacaaatagt ttctcttgcc cttcaggagg caatctgtgt acttcgtcta aaaacagtac
     3841 tccaccgtct gcatcttgca acaatccatt tcgatcttca tctgcgccgg taaaagcacc
     3901 tttaacatag ccaaatagta tccccgacaa taattcagga ttattatggt attgcgcaca
     3961 attaagtact ttaaaaggag cattctcatg aataacgttc acttttttca taaactgata
     4021 agcagtatga acaaaaaaac tttttccaac tccagtatct ccagtgatca tcataggaag
     4081 ccctcttcca ggatagaaga cagcagtttt catttgttcc accgcatcgg ataagctcat
     4141 atcataccca atcatctttt gtagaatgga atctgtagaa ttgggctcca agtctgtttt
     4201 taattcagat atactttcgt atacatcttt taccggaatc aaaaagtgct cttcaaagcg
     4261 ctctttgatg gcaaataaca ctggacgagt attgatttta aatagaacgt tctttgcaac
     4321 taagtcattg gcaagtttac tggcatttgt tcttcccgtt cttaaaaatt gcgacaggtc
     4381 atttgtgtca aaaaagcact cttctaaatt actgatgcca atttcttcac attttgtgtt
     4441 tgcataagtc actatatcat ttttcatctt ataaacagtc ctttctaaac ttctatccct
     4501 taaataaata gcaaaaaaaa ggaagcaata tcgatatgct gtcctcttaa tttaataaag
     4561 cgctaatcta attcactgta ttatcatttt ttagtagtat agcacaatta tgaatgcctt
     4621 ttctttatat caaataaagt ttatataaaa aacctcatcc tgcaagaaag aaaaaatgaa
     4681 cccattcttt ttatactagg tcttaaaaag acagaacatc tgctagaaga tagaagagaa
     4741 taagagttat atatgttgga agatattctt agaaaaaaga caaaactttt agaacacgaa
     4801 aactatattg aacgaataaa atgaaaaaat gattaaaaaa tcattttatt atttacgttt
     4861 acattctaat atgttaaatt gaatataact taaacaggca tgtgactggt aatgcaggca
     4921 ggacctaaat aagttgaata acaatgtatg cgtttcaata cacgtttgcc ttgttgtcaa
     4981 tttatttagt ttctgcctgt tttttgtgtt gaggatggcc acttcgactc aaaagttcat
     5041 cactcaaaaa agaaaagagg gaaacaccat gaattacaaa caaacagcag aagaagtatt
     5101 gcagtacatc ggtggggaag aaaacatatc ccatttggag cattgctcaa ctcgtttacg
     5161 ttttacgtta aaagacaaca gcaaggtaaa tatgagccag ttagaaaaag tggatggcgt
     5221 tatgggcgtt cgccaaaatg tgcaatgcca agtaatcatt ggaaacgatg ttgttgaagt
     5281 gtatgatgaa gtgaaagcgt tattaggtga caatgtttca aatactgaag aagcaccaaa
     5341 acaaaaacaa aaattaggtt cagttctatt agattttatt atttctattt tccaaccttt
     5401 aattcctgcg attgcaggtg gaggagtatt gaagtccttg ttgctactag cttctatctt
     5461 agggctgatt agtgaccaat ctcaaaccta tcagatttta aatttggtcg gcggggcacc
     5521 gctttatttc ttgcctattc tggtggcaat gactacggct aataaattga aagtcaatca
     5581 attggttgca gtatctgctg tcggtgcatt gatccttcct gaaatgacag ctatgttggc
     5641 ggaaggtgct acattcttat cttttggatt ggataatata gcgtatgcat ctcaagtatt
     5701 cccagccatc ttaactgttt tattttatgc tcaacttgaa aaatggttta caaaagtttc
     5761 accaaaacca attcgtattt tctttgtacc tatgatgagc ttattgatta cagttcctat
     5821 tgctttgttg cttctaggac cattaggtta taatgtagga acagctttct cttctatcat
     5881 tgtgtctttg tacaatcaat ttggatgggt tgcaaccgga gtcttagcag ctgtactgcc
     5941 attaatggtt gtaacgggta tgcataaagc aatgatccct tacgctgttt catccatgag
     6001 tgaattgggt gcagaacttc tttatctccc ggcttcattg gcacacaata tttcagaagc
     6061 tggcgcatgc tttgctgtca gtatcaaaac aaaagacaaa aaattgaaat ctacggctgt
     6121 ttctgcgggt atatctgcat tattcggaat tactgaacca gctctttacg gggtaacgat
     6181 tctgcacaaa cgtgttttat atgccgttat gttttctagc ctgatcgggg gagcatttgc
     6241 aggaatcgtt gcacttcaag cctttgcttt agtgggtcct gggattgcaa gtatcacgat
     6301 gttcgctgac aaagctgacc caatgaatct ggtttgggca tttgcagtat cggggatttc
     6361 atttgtggtt gcttttgctg cagcgttggt tctttataaa gataaagaag ttgtcaatga
     6421 agttgaaact aagatggaaa cggccgttgt ttcagatgct gttctttcaa gtcccgtgaa
     6481 tggaaaagta atctcactat cagaagtaaa agacactgtt ttttctagtg gtatggtagg
     6541 tgatggagta gcaatcattc ctgaagaagg gatattagta gctcctgaag atggagaaat
     6601 cacaatggta tttgaaacga agcatgctat tggtttaaaa acggctaatg gtgcagaact
     6661 tctttttcat attggtattg atactgttca gttagaagga aaagggtttg aggcatttgt
     6721 tcgttctggt gaaaaagtag ccaaaggaca aaagctgatt gcatttgata ttgatttaat
     6781 caaagaagca ggattcgacc ccacagttat ctgtgtggta accaataagg ataattacac
     6841 tatccgttca tttaacctag aaaaattggt aaccaatgat agtgatctct tagctatcag
     6901 tccgatagct taaacacaag atagtgaaaa aaaatatatt gaatgaagga atagaggaga
     6961 atagaataat gacaaacaca acaagttttc caaaaggatt tttatggggc ggcgcgatag
     7021 cagcaaatca agtagaaggt gcttggaatg tagacggtaa aggtctttca gtagcggata
     7081 tggctactta taaaccaaat ttagacaaca aagattttgc tgctcatatg catgtcaccc
     7141 tgcagtctat aaaagaagct agtgaagaca aatctgataa atggtaccca aaaagaaggg
     7201 gcgttgattt ttatcatcac tataaagaag atttagcttt atttgccgaa atgggcttta
     7261 aaaccttgcg cctctctatt gcttggactc gcttgttccc tacaggagaa gagctggaac
     7321 cgaatgaaaa aggggttgca ttttatgaaa acgtctttaa agaaatgcaa cgtttaggaa
     7381 ttgagccgat tgtgacacta tctcattatg aaatgccatt agctttagca gttaaatata
     7441 atggctgggt ggagcgtcga gtaattgatg attttgttcg cttcgctaac gtttgttttg
     7501 atcgcttcgg caaatacgta aaatattggc tgacatttaa tgagatagac agcatccacc
     7561 gtcatccatt tacaacagct ggaattatcc aagagaaaag cgcagaaggt caagaagctc
     7621 aagatatcta tcaagcattg catcatcaat ttgttgcgag tgcgttagtg acaaaagatg
     7681 ctcatgaaaa aattccagga agccaagttg gttgtatgtt aacgaaattg atgacttatc
     7741 cattaacttg cgcaccagaa gacgttgagc tgaccttgaa aaagaactta gaaaataatt
     7801 tttatgcaga tgttcaagtt aagggagaat atcctgctct aatcgaaaag gatttggaaa
     7861 atcggggaat tcagattaaa atggaagatg aagatcgaga aattttaaag aaacataccg
     7921 tagattttgt ttctttcagc tattacatgt ccatggcaga atcagctgat ccaaacgcag
     7981 aacgcacacc gggaaatact gttttagggg ttaagaatcc tcatttgcct tcaacagatt
     8041 ggggctggca aatcgatcca aaaggtttga aaatttcgtt gatcgaactt tatgatcgtt
     8101 accaagtacc gttgatgatt gtggaaaatg gtatgggagc agtcgatcag gtagtagatg
     8161 gtaaaatcca tgatccgtac cgcatcgact actttaaagc acacttccaa caaatgaaag
     8221 aagcaatcga tgaaggtgta gatttgatag cttatactag ctggggacca attgatttag
     8281 ttagtgcagg aacttctcaa atgtctaaac gatatggatt tatttatgtg gatgcagacg
     8341 atgaaggaaa tgggacatat aaccgcttga aaaaggattc gttcaactgg tacaaagaag
     8401 tgatcgaaac aaacggtgca tccttattcg agtagtctcg atctttttaa gcagcgatag
     8461 ggggataatg agtgatttca ataaaaaaag tattgaattc aagtgtggta cttgttgaag
     8521 aaaatggcaa agaaatgatt gcattaggta aagggatagg ctttggacag aaagctgggg
     8581 atgaaatatc aggagataaa gtagataaaa tatttctgcc ttttgaagaa aagaaatctt
     8641 cacaactatt agagttagtt gaagaaatac ctattgaatt ttttgaaatc actcgtacta
     8701 tcgtttttga agcagaaaaa ggattagata aaaaactgaa tcctggagtc tatttaacct
     8761 taacagacca cctgcatttt gcagttgaac gcgcacaaaa aggggtaaat attgcaaacc
     8821 gtttgtactg ggaaataaaa atctactatc ccaaagaatt tcaaattggg aagtacgcac
     8881 tcaccctttt gaacgagcaa tatggaattg atcttcctaa agaggaagcc tcaaacattg
     8941 ctttccattt gatcaatgca caatcggaag atcctgatag cggcgctgga ttcaagtatg
     9001 caaaaatgat cggcgggatc gtcaatttgg tccggtattc gttgcagaaa gatatcgata
     9061 ctaattcgat ccattatgcc cgcttcatta cacatgtacg tttctttgta gaaagatatt
     9121 attctgatgc tttgttggat gatggtgagg aagaattcta caatcaaatg tggatcttat
     9181 acccgtctgc catggaaagc gcagctaaga tcaaagacta cattgaaaaa gtttatcata
     9241 aaacaattcc gaacgatgaa gttgtatacc taggtgtcca catcaatcgg ttgatgaaac
     9301 atgctaatgg gtgagcgctc agtaatacta ttgatgcttt taaaatcttt agagatggat
     9361 tatagtaaaa acaaggtgat ttccagctgt ttgttatcta taagagacat ttaaaaagga
     9421 ttaacgtaag ataataaaaa at
//
LOCUS       DACGEU010000103         9432 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.106, whole genome shotgun sequence.
ACCESSION   DACGEU010000103 DACGEU010000000
VERSION     DACGEU010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9432)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9432)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9432
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.106"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            <1..680
                     /locus_tag="IXR40_002439"
     CDS             <1..680
                     /locus_tag="IXR40_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAQ4362240.1"
                     /translation="YFSRFSLATREAVQWIVIDMYAPYVSLVKKLFPNAQLIIDRFHI
                     VQHIGRTFLNHRVKETTARLKGTSHSQRGLGKKLKRYWKLLQKEEAKLNYEKRVWRAS
                     FKDYLTESEIVDRLLSACPNLRQGYQLYQDILYAVKKRDQSLFEDCLNREVSGLPETY
                     TTTLRTFKKFLPQIQNALHYSYSNGPLECLNNHIKVLKRNAYGFRSFYNFKLRIMIRH
                     GKTFLTK"
     gene            800..1000
                     /locus_tag="IXR40_002440"
     CDS             800..1000
                     /locus_tag="IXR40_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAQ4362241.1"
                     /translation="MIEEEQKNIWDRYYKADPSSKNTKIGESGLGLSIVKELVRLHHG
                     SIEVTSRKNEGTTFLIQFPKEK"
     gene            1076..1273
                     /locus_tag="IXR40_002441"
     CDS             1076..1273
                     /locus_tag="IXR40_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362242.1"
                     /translation="MVECLKNKKMEANFVKAVISGSIVFQEEYRDMEKDFSKKGIELI
                     DYPRSCPILDKEYPEILTTFF"
     gene            complement(1570..3117)
                     /locus_tag="IXR40_002442"
     CDS             complement(1570..3117)
                     /locus_tag="IXR40_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HAQ4362243.1"
                     /translation="MNITFLETSDMHGYVSPTDYSGRTDLALGTAKVSSKLKELRAKA
                     DGPVITIENGDFIQGSPLSYYLAKEYGSAKELTDLINQMSYDVQVLGNHEFNYGVDYL
                     EEAIKNYQAPILGANMVNKNDQPYFGNAYKIIEKVGVKIAILGLTTQYIPHWEKPETL
                     AGITFKSIVETAKEYVPLLRKQADLVIVSYHGGFEKDLLTGEDTEALTGENEGYELLQ
                     QVEGIDALFTGHQHRKIAETVHGVPVVQPGYRGEFIGEIRLTVEKKEGQVVVTDHQVA
                     LHSVEKSEPDPEILAAIVPVEEKLEKWLDQPLGKVNGNMRINDPMQARLEEHPYVEFI
                     NRVQLFASGSEISGTALFNNEGKGFGETITMRDVITNYIYPNTLAVIQINGADLRAAL
                     EQTANYLAVENNQIVFNPAFIQPKPQYYNYDMYEGIQYTIDMKQPVGQRITELRFKGH
                     PVLPQQMLEVVTNQYRAIGGGNYAMFGAEKIVREIQIDMTELIADYLNIHPRIEAKVN
                     HNFQVIL"
     gene            complement(3201..4004)
                     /locus_tag="IXR40_002443"
     CDS             complement(3201..4004)
                     /locus_tag="IXR40_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HAQ4362244.1"
                     /translation="MNILHISDIHFRREYEACEEGYKGMLATMQNPLIPLEQCIHHLL
                     QQTPLDLVIISGDLTEDGEIDDYRYLKTWLENALGETTILVTLGNHDIKEHFWVGWCD
                     EAASSAPYNQIVKYPEFTVISFDNSSYGYADGIVDDQQFQWLKKALEQEKDQPIFLVT
                     HHHLLSHQSSIPKWPGTERFLKLIAPYDIRCILNGHTHHTFTDEINGIPYFTVSSMSF
                     VGEDEGDGFVRFEERHGYNLYHLDQGRIVRQTTENFIPGNILKTLQMKD"
     gene            complement(4007..4789)
                     /gene="phnE"
                     /locus_tag="IXR40_002444"
     CDS             complement(4007..4789)
                     /gene="phnE"
                     /locus_tag="IXR40_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter, permease protein
                     PhnE"
                     /protein_id="HAQ4362245.1"
                     /translation="MMLREMNRRTLLSLVALVILVILSAATLDYSGLSTFSPSMGMDV
                     LRGLGQPDWQFLYDGSGEDLISLLLLTIGIACLGTMIATVLAIPITLISAVNLWQAHP
                     WVTKIGKLICNVLRAFPELVFAIIFVKVVGPGPFAGVMAIGVHQIGMLGKLFTEEMEA
                     MDERLVEEMHAVGANFWQTIFFVRIPYLMPIYCSLALNHFEIAVRSAATLGLVGAGGI
                     GAPLIFAIQTRSWSKVSIILIGVVVTVFILDQITGIIRKRLR"
     gene            complement(4786..5565)
                     /gene="phnE"
                     /locus_tag="IXR40_002445"
     CDS             complement(4786..5565)
                     /gene="phnE"
                     /locus_tag="IXR40_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter, permease protein
                     PhnE"
                     /protein_id="HAQ4362246.1"
                     /translation="MSLKETVHFKWYKHLLILLFLIVCFQGSAWITSADFSQVFQNSN
                     QMTVFLSRFIHPDFSYLPKLVEPMVKTLQMSLLGTVIGLILAIPVSFLATTVVTENRL
                     LSTIFRFLLGLVRTIPTLLLAALFVAVFGIGEATGVLTIAVFTFGMVSQLMFQAIETI
                     DFGPIEAAAAVGANKMQIAIWSIAPQVLSQFASYAFYAFEVNVRASTVLGYVGAGGIG
                     VILNSSLALLNYERVSIIILTILVTVAIVDKLSERVRRSLL"
     gene            complement(5537..6328)
                     /gene="phnC"
                     /locus_tag="IXR40_002446"
     CDS             complement(5537..6328)
                     /gene="phnC"
                     /locus_tag="IXR40_002446"
                     /EC_number="7.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter ATP-binding protein"
                     /protein_id="HAQ4362247.1"
                     /translation="MIIFDNVSKVYPNGVVGLKDIDLTIEDGEFVSIIGLSGAGKSTL
                     LRSINRLAETTKGDIRINGTSITKANKKELRQIRRQIGLISQSFNLVKRSTVQKNVLS
                     GRLGYYSTWKSILGLFTKEDYQQTKEALEKVGLSDKLQTRSDELSGGQQQRVSIARAL
                     VQQAPIILADEPVASLDPITTQKVMMDLKNINQTMDKTVIVNLHSVPLAREFSTRVLA
                     LKAAQVVFDGRPDDLTDERLEQIYGNAIFEEKAGEIDELERNRSL"
     gene            complement(6389..7318)
                     /locus_tag="IXR40_002447"
     CDS             complement(6389..7318)
                     /locus_tag="IXR40_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate/phosphite/phosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HAQ4362248.1"
                     /translation="MQFKQLAKGFIGVMLLTTLAACGSGNTSSSSEKESKEKLVVQFV
                     PTNNDGSMEAKAKPFAKYLSKKLDREVEVTLATDYSTIVEAMSSGQVDVGIMPPAAYV
                     QAKDAGAADAILTSQLGDYDQETGLPLKDKLTNTFKGEVLVRADSGLNKLTDLKGKNI
                     ATLSPNSASGYIYPVAELKDAGIDPTADTKMTTVNDIPSEITAVLNKQMDAAFVFEGA
                     RNVFASNFPDNDLFKDLKVLYLTKGDIPNDAIAVQPDMSKDLKAKIKETFLNMKDDKD
                     GKEAMALWGHQGYEEAADSAYDTIRDYTKKAAE"
     gene            7513..8196
                     /locus_tag="IXR40_002448"
     CDS             7513..8196
                     /locus_tag="IXR40_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic nucleotide-binding domain-containing
                     protein"
                     /protein_id="HAQ4362249.1"
                     /translation="MKKIHDTKQLTAYVEKHNLQDYMDSDILAMASLLFFEKEEHLIQ
                     TGKTSDYLYFLVDGTVMVYSYSSDTQNICIDYAKPATPLGEASSLWELSPKSSVKAVT
                     KCICISIPLNQYRTQLQKDVRFLQNICQLLSYRLNSGINLANSLTEPVETRLAKFILT
                     HHENERFSFRLTTCASILNVSYRHLLRTITNFREENIIEKKKNYYLIHDIEALEDLAE
                     NISSPVKAE"
     gene            8357..9400
                     /locus_tag="IXR40_002449"
     CDS             8357..9400
                     /locus_tag="IXR40_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HAQ4362250.1"
                     /translation="MKKILVSLLFLVSLVTLVGCSQSQGEKQSEKEKSKIALVLGFGG
                     VDDRSFNQAGWEGLEAWGKEKKLTAKKDFTYIETNNPEDNSTNIDQAIRNGFTTIISL
                     SYLQAEELENAAKDNPKLKFALVDGEITGKKNISSATFKDQESAYLAGLAAAYTTKSD
                     QVGFIGGMEGPVIQRFQSGFEAGVKAGATALNKEITVNVQYAASYDSLDKGKAIAASM
                     YKEGVDILYQAAGSTGAGVFQEAKARNENDYSRKVWVIGVDRDQADEGDYKMENGETG
                     NFTLTSTKKNVGAEVKEFAETSHNDKFPGGKHLTFGLKEEGVDLTKGQLSEEAYQAVS
                     DAKEKIISGDFRL"
BASE COUNT         2893 a         1933 c         1869 g         2737 t
ORIGIN      
        1 gctatttttc tcggttttca ttagcgactc gtgaagccgt tcaatggatt gttattgata
       61 tgtatgcgcc ttatgtttca ttggtgaaaa agcttttccc gaatgctcag ttgatcatcg
      121 accgtttcca catcgtccaa catattggca gaaccttctt gaatcatcga gtgaaagaaa
      181 ccacggcacg gcttaaagga acttcccact ctcaacgagg gttagggaaa aaattgaaac
      241 gctattggaa actcctacaa aaagaagaag caaagttaaa ctacgaaaaa agggtttggc
      301 gtgccagttt taaagattat ttgactgaaa gtgagattgt cgatcgactg ttatctgctt
      361 gtcccaacct gcgccaaggc tatcagttat accaagacat tctttatgcg gtaaagaaaa
      421 gagatcagtc attatttgag gactgtttaa acagagaagt cagcggtctt cctgaaacct
      481 atacaaccac tttacgaacg tttaaaaagt ttctgccaca gatccaaaat gcgcttcact
      541 acagctattc aaatggacca ttggaatgtt taaacaacca catcaaagta ttaaaacgca
      601 atgcgtacgg ctttcgcagc ttttacaatt tcaaactacg gatcatgatt cgtcatggca
      661 aaacattttt aaccaaataa acagaacaga aagagagttt cttctttctg ttctgtccaa
      721 attattctaa gatttctctt taccaacatc atttgacaaa gagcctgtat ttattactgt
      781 cgaggacaat ggcatcggca tgattgaaga ggaacaaaaa aacatttggg atcgctatta
      841 taaagccgat ccgtcaagta aaaatacaaa gataggcgag tcaggtcttg gattatcaat
      901 cgtgaaggaa ctagtgcgcc tgcaccacgg ttcaattgaa gtgaccagcc gaaaaaatga
      961 aggaacgacc ttcctgatac aatttccaaa agaaaaataa aattaccagt aaaaaaccgt
     1021 ggagagatag ctgctattga tttttgctat gtcttttctt tgagaggtat ccggtatggt
     1081 ggagtgtctg aaaaataaaa aaatggaggc caattttgtg aaagctgtta tttctggaag
     1141 tattgttttc caagaagaat atcgagatat ggaaaaagat ttcagtaaaa aaggcattga
     1201 attaattgat tatcctcgct catgtccgat cctagacaaa gagtatccag aaatcttgac
     1261 gacttttttt taaatatcgc agcagcggat ttattttttg tatttaatca agatcggaaa
     1321 ggggtattag gctatattgg tgccgcaact ttttcagaaa tgaagtattg tctgatgcaa
     1381 aatcttattc atggaaaaag gatcaaaata gtcttattta aggaaccatc agaggaaaat
     1441 tttttgtttt gatgaggtag atcgctggct aaagaatggc tggatggaaa tcagacagcc
     1501 taacaatttg gcataacaaa ggtgtgggca aaaaactgct cacacctttt tgaatttttt
     1561 atttatatac tacaaaatca cttgaaaatt atgattcact tttgcttcga tgcgtgggtg
     1621 aatattcaaa tagtcggcaa ttaattcggt catgtcgatt tggatttctc ggacaatttt
     1681 ctccgcacca aacatcgcat aatttcctcc gccgattgcc cgatattgat ttgtcaccac
     1741 ttccagcatt tgttgcggaa gaacggggtg acctttaaaa cgaagttcgg taatccgttg
     1801 tccaacaggc tgtttcatat caatagtgta ctgaatccct tcatacatgt cataattgta
     1861 gtactggggc ttaggctgaa taaaggctgg attgaatacg atttggttat tttctacagc
     1921 taaataattt gcggtctgct ccaacgccgc tctcaaatct gcaccattta tttgaatcac
     1981 tgccagagta ttcggataaa tatagttggt gatgacgtcc cgcatcgtga tcgtctcacc
     2041 aaagcctttt ccttcattat tgaataacgc agttccagaa atctctgagc cgctggcaaa
     2101 taattgtaca cgattaataa actctacata gggatgttcc tcaagacgag cctgcatcgg
     2161 atcattaata cgcatatttc cgttcacttt acctaagggt tgatccaacc atttctctag
     2221 tttttcttct accggtacga tcgctgcaag aatttctgga tcaggctctg atttttcaac
     2281 tgagtgtaaa gcaacctggt gatctgtaac aaccacttgc ccctcttttt tctcgacggt
     2341 aagacgaatt tcaccgatga actcgccacg atagcctggt tgaacaacgg gaactccatg
     2401 aaccgtttca gcaattttcc ggtgctgatg accggtgaaa agggcgtcaa tgccttcaac
     2461 ctgctgcaat agctcgtagc cttcattctc tccagttagc gcttctgtgt cctcaccggt
     2521 taacaagtct ttttcaaatc cgccgtggta actaacgatt accaagtctg cttgtttcct
     2581 taatagagga acatattctt ttgctgtttc gacgatactc ttaaacgtaa ttcctgctaa
     2641 ggtttctggc ttttcccagt gaggaatgta ttgtgtcgtt aatcccaaga tagcaatttt
     2701 tacacccacc ttttcgataa tcttataggc gtttccaaag tatggttggt catttttgtt
     2761 caccatattg gctcctaata taggcgcttg ataattctta atcgcttcct cgagataatc
     2821 cacaccatag ttaaactcat gatttcccaa cacttgaaca tcatagctca tttggttaat
     2881 caagtctgta agctctttgg ctgaaccata ttctttagca agataataac tcaaaggaga
     2941 cccttggatg aaatcaccat tttcgatcgt aattaccggt ccatctgctt ttgcccgtaa
     3001 ttccttcagt ttcgacgata ctttagccgt tcctaaggcc agatcggttc tgccggaata
     3061 gtctgttggt gaaacatagc catgcatatc acttgtctct aaaaacgtaa tgttcattct
     3121 gcgtgctcct ttagctgact caaaatagaa aaaccgaagc gtattcagct gttcggtctc
     3181 tttttttgat ttataatgcc ttaatccttc atttgaagtg tttttaaaat gttgcctgga
     3241 ataaagtttt ctgttgtctg gcgaacaatc cttccttgat cgagatgata aaggttatac
     3301 ccatgacgtt cttcaaagcg tacgaagcca tcgccttcat cttcaccaac aaaggacata
     3361 ctcgatacag taaaataggg gatcccatta atttcatcag taaatgtgtg atgggtatga
     3421 ccgtttagga tacagcgaat atcgtaaggt gcgattagct tcaagaaacg ttcggtacca
     3481 ggccattttg gtatactgct ttggtgagac agtagatgat gatgggtgac caagaaaatc
     3541 ggttggtctt tttcttgctc taaggctttt ttcagccatt gaaattgctg atcgtccact
     3601 ataccatctg cgtatccata gcttgaatta tcaaaggaaa tcactgtaaa ctcaggatat
     3661 ttgactatct ggttgtacgg ggcagaagag gcggcttcat cgcaccagcc tacccaaaaa
     3721 tgttctttga tatcgtgatt gcctagagta acaagaatcg tcgtttctcc tagcgcattt
     3781 tccagccaag tcttcaagta tcgataatcg tctatttcgc catcttcggt taaatctccg
     3841 ctgataatca caaggtccaa gggtgtttgc tgcaggagat gatgaatgca ttgctccaga
     3901 gggataaggg gattctgcat cgtagccagc attcccttat agccttcttc acaagcctca
     3961 tactctctgc gaaagtgtat atctgatata tgcaatatat tcattcttat ctcaatctct
     4021 ttcttataat tccggttatt tgatctaaaa taaacacggt tacgactacg ccaatcaaaa
     4081 taatactcac tttgctccaa gaccgagttt gaatcgcgaa tatcaatgga gcaccgattc
     4141 cgccagcgcc aactaagcct aaggtagccg cactacgaac cgctatttca aaatgattta
     4201 atgctaaaga acaataaatc ggcatcaaat aggggatgcg aacaaagaaa atcgtttgcc
     4261 aaaaatttgc tcctaccgca tgcatttctt caacaagtcg ctcatccatc gcttccattt
     4321 cttctgtaaa aagtttgcca agcattccga tctgatggac gccaatcgcc ataacaccag
     4381 caaaggggcc aggtccgacg actttcacaa aaataattgc aaaaactagt tcaggaaaag
     4441 ctcgtaaaac attacagata agcttgccaa tttttgttac ccatggatgt gcttgccaga
     4501 ggttaaccgc actgatcaag gtaatgggaa tcgctaatac cgtagcgatc attgtcccta
     4561 aacaggcgat tccaatggtt aataatagca aactaatcaa atcctcgccg ctgccatcat
     4621 atagaaactg ccaatcaggc tgacctaacc ctctcaaaac gtccattccc atggaaggag
     4681 agaaggtgct taatccagag taatccagag tagcggccga caaaataacg agaatcacta
     4741 aagcaactaa tgataaaagg gttcttctgt tcatttcacg aagcatcata acagggacct
     4801 cctgacacgt tcacttaatt tatcaacgat cgcgacagtt actaggatcg ttagaataat
     4861 gattgaaact cgttcataat tcaaaagcgc aagtgaggaa tttagaataa cgccaatacc
     4921 accagctccg acatatccaa ggacagtaga agcacgaaca ttcacctcaa acgcgtaaaa
     4981 agcatagctc gcaaactgac tcaaaacttg tggagcgatc gaccaaatag cgatttgcat
     5041 tttatttgct ccaacagccg cagcggcttc aatcgggcca aagtcaatgg tttcaattgc
     5101 ttgaaacatt aattgtgaca ccataccaaa agtaaagaca gcgatagtca acacgccagt
     5161 cgcttcacca attccaaaca cagcaacaaa aagcgcggct aaaagcaggg tagggatggt
     5221 ccgtactaaa cctaaaagaa aacgaaagat ggtagaaaga agacggtttt ctgtcactac
     5281 agtggtcgct aaaaaactaa cagggatcgc taaaattaag ccaatgaccg ttccaagcaa
     5341 agacatttga agtgttttca ccataggctc gactaattta ggtaaatagc taaagtctgg
     5401 atgaatgaag cgtgataaaa agacagtcat ttgattggag ttttgaaaaa cctgagaaaa
     5461 atcagctgac gtgatccagg cacttccttg aaaacaaaca attaagaaca gaagaataag
     5521 caggtgttta taccatttaa agtgaacggt ttctttcaag ctcatcgatt tcgcctgcct
     5581 tttcttcaaa gattgcattg ccataaattt gctctaagcg ttcatcggtt aagtcgtctg
     5641 gacgaccatc aaagacaacc tgagcagctt ttaacgcgag cacacgcgta gaaaactcac
     5701 gagccagagg gactgaatgc agattgacaa tgactgtttt atccatcgtt tgattgatat
     5761 tttttaggtc catcataacc ttttgagtcg tgattggatc taatgatgca acgggttcat
     5821 ccgctaaaat aatgggggct tgctgcacga gtgctcgcgc aatggatact cgctgttgtt
     5881 gcccaccact gagctcatca ctgcgtgtct gcaatttatc agacaaacca actttttcca
     5941 gtgcttcctt tgtctgctgg tagtcttcct tcgtaaaaag acctaaaata cttttccaag
     6001 tggagtaata gcccaaacgt ccagatagca catttttctg aaccgtacta cgctttacca
     6061 gattgaagct ttgcgagatt agaccaatct ggcggcgaat ctgtcgcagc tcttttttat
     6121 tcgcttttgt aatagaggtt ccattaatgc gaatatctcc tttggtggtt tctgccaagc
     6181 gattgatact gcgcagcaga gtgctctttc cagcaccact caaccctatg atggaaacaa
     6241 attctccatc ttcaattgtt aagtcaatat ccttcaagcc aacaacgcca ttgggataga
     6301 ccttcgaaac attgtcaaaa ataatcatta tccttctcca tttttttaag tgtaagcaaa
     6361 aaaaagcttg ctgacactta ctgatgtttt attctgctgc ttttttcgtg tagtctctga
     6421 tcgtgtcata ggcagaatca gcagcttctt catagccctg atgcccccac aaagccattg
     6481 cttctttgcc atctttatca tccttcatat ttaagaaggt ctctttaatt ttcgctttta
     6541 aatcttttga catgtcaggc tgtacagcga ttgcgtcatt cggaatatcg ccttttgtca
     6601 ggtacaggac ttttaaatcc ttaaataaat cattatctgg gaaattcgaa gcaaaaacat
     6661 ttcgcgcgcc ttcaaaaaca aacgccgcat ccatttgctt gttcaacact gcggtaatct
     6721 cactcggaat atcattcaca gtggtcatct ttgtatctgc agtaggatca atcccagcat
     6781 ctttcaattc agcgacagga tagatgtagc cgctagcaga gttaggactt aaggttgcga
     6841 tattttttcc ttttaaatca gttaacttat tcaatccgct atcggcacga accaatactt
     6901 ctcctttaaa ggtgttcgta agtttgtcct ttaatggcaa gccagtttct tgatcataat
     6961 cgccgagctg agaagtcagg attgcatctg cagctccagc atcctttgct tgaacatagg
     7021 ctgcaggcgg cataattccg acatcgactt gaccagaaga catcgcttcg acgatcgttg
     7081 aataatcagt agctaacgtc acttctacct cacgatctaa ctttttcgat aaatacttag
     7141 caaatggttt tgcttttgcc tccatactac catcattgtt tgttggaacg aattgaacaa
     7201 ctaatttttc tttgctctct ttttctgagc tgctacttgt attcccagaa ccgcaggccg
     7261 ccaaagtggt caataacatg actccgatga acccttttgc taactgtttg aactgcattt
     7321 ttctcctcct gttggatata atttctaata cgtctaaatc atagcaggga atcaaaatca
     7381 atgaagtgac gcacgtccta ttttacacaa cttttacata caatttacaa acaattataa
     7441 ataattattc gtattgagcc gaaaaacaat ctaagctata ataaagaaaa acttcttaga
     7501 ggtgacgatt tcatgaaaaa aatccatgat acgaagcaat taactgctta cgttgagaag
     7561 cacaacctgc aggattatat ggattcagat atattggcaa tggcttcttt actttttttt
     7621 gaaaaggaag agcacctcat tcaaacggga aaaacctcag attatttgta ttttttagtg
     7681 gatgggacgg taatggtgta ctcgtattct tctgatacac aaaatatttg catcgattac
     7741 gcaaagcccg ctacaccact cggcgaagcc tcttcattgt gggaattatc gccgaaaagc
     7801 agcgttaaag cagtgactaa gtgcatctgt atcagcattc cgctaaatca atatcgaaca
     7861 cagcttcaaa aagatgttcg ctttttgcag aatatttgcc agttactaag ttatcgttta
     7921 aattccggga taaatttggc gaactcactg acagaacctg ttgaaactcg tttagcaaag
     7981 tttattttga cccatcacga aaacgaacgt ttctcatttc ggttaaccac ctgcgcctca
     8041 atcttaaatg tcagttatcg acatctttta cgaacaatca cgaattttcg tgaggagaat
     8101 attatcgaaa agaaaaagaa ttattacttg attcatgata tcgaagcttt agaggactta
     8161 gctgagaata taagtagtcc agtaaaagca gaataacagc tataaaaaaa cagcagtcag
     8221 aagtgattgc tggttttttg atagtggaga aattgggaaa cggaaaatct tcgttgaaga
     8281 gtagtgttct atatattggt atgctatact tttaaaagtt caatgtgtca agacacataa
     8341 aaaggggaga aaaattttga agaaaatact tgtttcattg ttgtttttgg tgtcattagt
     8401 aacgttagtc ggctgtagtc agtctcaggg ggagaagcaa agtgaaaaag agaaaagtaa
     8461 aatcgctttg gttcttggat ttggcggggt tgatgaccgc tccttcaatc aagctggctg
     8521 ggaaggatta gaggcttggg gaaaagagaa aaagctgaca gcaaaaaaag attttacgta
     8581 tatagaaacg aacaatccag aggataacag taccaatatc gatcaggcaa tcagaaacgg
     8641 ctttaccacc attattagct tgagctactt gcaagcagag gaactggaaa atgctgctaa
     8701 agataatcca aagttgaaat ttgccttggt agatggtgag attactggga aaaagaatat
     8761 ctcatcagca acctttaaag atcaagaaag tgcgtattta gcaggactag ctgccgcata
     8821 tacgacaaaa agtgatcaag taggctttat tggtggaatg gaagggcccg tgatccaacg
     8881 tttccaaagc ggatttgaag ctggcgttaa ggcaggggcc acagcactga acaaggaaat
     8941 tactgttaac gtacaatatg ctgcatccta tgattcgcta gataaaggaa aagctattgc
     9001 tgcttctatg tacaaagagg gagtcgatat tctttatcag gcggcaggaa gtactggagc
     9061 tggggtgttc caagaagcaa aagcccgcaa tgaaaacgac tatagcagaa aagtatgggt
     9121 gattggtgta gatcgcgatc aagcggatga aggggattat aaaatggaga acggcgagac
     9181 agggaatttc acgttgactt ctacaaagaa aaatgtcggt gcagaagtca aagaatttgc
     9241 agaaacttct cataacgata aatttcctgg cggcaagcat ttgacctttg gtttgaaaga
     9301 agaaggggta gatctgacaa aaggacaatt atcagaggaa gcctatcagg cagtttcaga
     9361 cgcaaaagag aaaatcatca gtggtgattt cagactgtag acaaagtcca ttttatggat
     9421 gatgtctaca gt
//
LOCUS       DACGEU010000104         9253 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.107, whole genome shotgun sequence.
ACCESSION   DACGEU010000104 DACGEU010000000
VERSION     DACGEU010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9253)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9253)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9253
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.107"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(62..1093)
                     /gene="queA"
                     /locus_tag="IXR40_002450"
     CDS             complement(62..1093)
                     /gene="queA"
                     /locus_tag="IXR40_002450"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HAQ4362251.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            1286..2461
                     /locus_tag="IXR40_002451"
     CDS             1286..2461
                     /locus_tag="IXR40_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Members of the family are the ATP-binding subunit
                     of ABC transporters for substrates such as betaine,
                     L-proline or other amino acids, choline, carnitine, etc.
                     The substrate specificity is best determined from the
                     substrate-binding subunit, rather than this subunit, as it
                     interacts with the permease subunit and not with substrate
                     directly; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="betaine/proline/choline family ABC transporter
                     ATP-binding protein"
                     /protein_id="HAQ4362252.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEAIKLASRIAIMSEGRVIQFD
                     TPENILRHPANDFVEELIGEDRLLQAKPNATRVGEVMLNTAITITPEKSLQEAIKLMR
                     EKRVDTLLVTDNSNVLKGFIDVETLNKKRGKVSSVGDILNKHVFYVKESAYLRDTLQR
                     ILKRGLKYVPVVDEQNKVVGILTRASLVDIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            2465..3106
                     /locus_tag="IXR40_002452"
     CDS             2465..3106
                     /locus_tag="IXR40_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4362253.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            3103..4020
                     /locus_tag="IXR40_002453"
     CDS             3103..4020
                     /locus_tag="IXR40_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HAQ4362254.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYGFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            4017..4688
                     /locus_tag="IXR40_002454"
     CDS             4017..4688
                     /locus_tag="IXR40_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4362255.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(5229..5717)
                     /locus_tag="IXR40_002455"
     CDS             complement(5229..5717)
                     /locus_tag="IXR40_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HAQ4362256.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(5918..6184)
                     /locus_tag="IXR40_002456"
     CDS             complement(5918..6184)
                     /locus_tag="IXR40_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HAQ4362257.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(6184..6447)
                     /locus_tag="IXR40_002457"
     CDS             complement(6184..6447)
                     /locus_tag="IXR40_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAQ4362258.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            complement(6440..6712)
                     /locus_tag="IXR40_002458"
     CDS             complement(6440..6712)
                     /locus_tag="IXR40_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362259.1"
                     /translation="MYWCCCIDSQALDSTFAKDDTLLPITLRLATASRKGVRSERGQR
                     SSLKRGLFLYVKKRKSLLNLSALLYFFDVLNQVRYNYIRKRRRDNG"
     gene            6923..7108
                     /locus_tag="IXR40_002459"
     CDS             6923..7108
                     /locus_tag="IXR40_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAQ4362260.1"
                     /translation="MALSYGNKKWSLDEAEIPTYEDTWHLRVEVKEEAENIGGCTLFG
                     KGFGNYDQDIKIKMFYS"
     gene            complement(7250..9073)
                     /locus_tag="IXR40_002460"
     CDS             complement(7250..9073)
                     /locus_tag="IXR40_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HAQ4362261.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
BASE COUNT         2755 a         1947 c         1765 g         2786 t
ORIGIN      
        1 ctttgtcata aaatctttgt aaagcttttt tgttattcaa aactagcggc ttttcataac
       61 cttatttcac gaacatcgca tctccaaaac taaagaaacg atagcgctct tcaatcgcat
      121 gctggtaagc agataaagtc aattctcttc ctgcaaaggc actaactaac atgactaaag
      181 tcgattttgg caaatggaaa ttagttgaga aagcttctac cactttgaat tcatagccag
      241 gcgtaatgaa aatatcagtc catccgctgt ctgctttgat ttctccatta aatttcgttc
      301 caatcgtttc taatgttcga attgaagttg ttccgacagc cacgattttc ccgccatttt
      361 tacgtacttg gttcaatcgc tcagccgctt cttccgtcaa acggtagaat tcactatgca
      421 tatggtgttc ttcaatttta tctacgctga caggtcggaa tgtacctaac cctacatgta
      481 gtgtcagata gactaattca acaccctttg cttcgatctc atcaagtaat tctttcgtaa
      541 aatgcaatcc agctgttggc gctgcagcag aaccattttc tttcgcatag acagtttgat
      601 agcgatctgg gtcttccaga cgttctttga tatatggagg caatggcatt tctcccaatg
      661 attcaagaat ctctagaaaa attccttcat actcaaagtc aatgatccgt ccgccgtgtt
      721 ccaattcttc tttcactact gcttgcaatc tgccatcacc aaaagagatt cttgtcccaa
      781 ctttggcacg tttcgcaggt ttgatcaatg tctcccacgt atctccttgt gtattcgtta
      841 gaagaaggac ttctaaatgc gcaccagtat ctggtttttc tccatataaa cgagcaggca
      901 gaactcgtgt attattcata actagcgcat caccaggctg taactcttca atgatttcat
      961 ggaaatgttt atcttccatc tctccagttt tccgatccaa aacaagtaaa cgagaatgat
     1021 cgcggtcttt taatggtgtt tgtgcgatta attcttccgg caagtcaaaa tcaaaatctt
     1081 ctgttgttaa catatcgtca ctcactttct atcatgtgct tcatcattct atcatgtttt
     1141 tcgttctgtt ggcaaaatca gcactttttc acttctattt tttgttttcc taaataaaaa
     1201 aactacccta tttgtatttt ttcattgttt taggcatact agtaatagat agttcttcat
     1261 tgaaaataga aaaagaggtg gcaccatgat tgaatttcaa aatgtgtcaa aaatttataa
     1321 aggtggaaaa gtcgctgtag aggacgtcaa tctttcattt gaaaagggtg agttcatttg
     1381 ttttatcggt acgagcggaa gcggaaaaac gacgacgatg cggatgatca accgaatgac
     1441 tgatccaaca caagggaaaa ttttgattga tggaaaatcc atccaagaaa ttgatccagt
     1501 ggaattgcga cgtcagatcg gctatgttat ccaaagtatt ggattgatgc ctcacatgac
     1561 gatccgtgaa aatatcactc ttgtccaaaa attgttgaaa gtcagtcaag aagaacggaa
     1621 taaaacagct gaaaaaatga ttgatcttgt ggaattgccc cgtgagatgt tagatcgcta
     1681 cccacatgaa ttatctggtg gtcagcagca gcgtattgga gtcgttcgtg cccttgcagc
     1741 gaatcaagat atcatcttga tggacgagcc attcggtgcg cttgatccaa tcactcgtga
     1801 ttccttgcaa gaccttgtca aagatttaca agagcgtttg ggaaaaacga tcgtatttgt
     1861 aacccatgac atggatgaag cgattaaact agcaagccgt atcgccatca tgagtgaagg
     1921 ccgtgtgatc caatttgata caccagaaaa tattttacgt catcctgcaa acgatttcgt
     1981 agaagagttg attggagaag atcgcctact acaagccaag ccaaatgcga caagagtcgg
     2041 cgaagttatg ctaaatacag caatcacgat tacaccggaa aaatcattac aagaagcaat
     2101 caaactgatg agggaaaaac gtgtagatac gttgttagtt accgataatt cgaatgtatt
     2161 aaaaggattt atcgatgtag aaacgttgaa taaaaaacga ggaaaagtat ccagtgtcgg
     2221 cgacattttg aataaacatg ttttttacgt aaaagaatcc gcctatcttc gtgatacctt
     2281 gcaacgcatt ttaaaacgcg ggctgaaata cgtgccggtc gttgatgaac agaacaaagt
     2341 cgtaggtatc ctgactcgtg catcattagt ggatatcgtc tacgatgtga tttggggaga
     2401 agatcccgca actactgatg ttgcagagtc agctactcct gaagaatcta aggaggtctg
     2461 acctatgcag cagttttttc atcagcacgg ttcagaaatt ctctcaaaag gttttgaaca
     2521 tctttatatt tcaggacttg ctttgatcat tggtatcatc attgctgtac cgcttggtgt
     2581 cttactgaca cgttttccaa aagctgccac gattgtgatt ggcttaacca gtgccttgca
     2641 gacaatccct tctcttgctt tattggcatt gatgatcccg ctatttggcg taggtaaatt
     2701 acctgcgatt atcgcactct ttatttattc attattgccg attttacgta atacgtacat
     2761 tgggatgaaa aatgtcgatt ggaattatcg ggatgtggca aaaggcatgg ggatgactga
     2821 gttccaatcc attttttccg ttgaattgcc cattgctatg ccaacgatca tggctggtat
     2881 tcgtttagct gccgtttacg tgattgcatg ggctacactt gcctcttata tcggcgctgg
     2941 tggtttaggc gatttgattt ttagtggact gaataattac caaccagatc tcattttggc
     3001 aggtacgatc cctgtaacaa ttttagcact attggctgat tggcttctag gtctcttgga
     3061 acaccggctg acaccgatcg cacttagaga ggagaatgaa gaatgaaacg tatactaaaa
     3121 atgaccatgg ttcttttctc tcttcttata cttgcgagtt gttccttccc tggtcttgcc
     3181 agcaatacag atgaagacac catttcgatc acaggtggaa tcacttcaga agcacagatc
     3241 ttagcaagtc tagttgccgg aatggttgaa cattatacag ataaaaatac cgcaatcatc
     3301 aacaatctgg ctactacaac tatcaaccat caagcgatga tgaacggaga tgcttcaatt
     3361 tcagcggctc gctacacagg aacagattta acgactacat tgaaccttcc tcctgaaaaa
     3421 gatccgaaaa aagcgtttgc taccgtgaaa gatgaatttg agaaaagata cggtcaaacg
     3481 tggttcccgt cctatggttt tgaaaatacg tatgtctttc ttgttcgaaa agacaccgca
     3541 caaaaatacc atctatctaa agtcagcgat ctgaaaaatg tagcggatga attagtagct
     3601 ggtgtagata cttcttggat caatcgtaaa ggagacggtt atgacggctt ccaagaaact
     3661 tatggcttct ccttcaattc gatattacct atgcagattg gacttgttta tgacgcagtc
     3721 gaagcaggaa aaatggatat tgttcttggc tactctacgg atggacggat cgccagttat
     3781 gatctagtca tgttggaaga tgatcgtcaa ttcttcccac catatgatgc tgctccagtt
     3841 gtagacaaca agatattagc tgatacgcct catttaaaag aagccttaaa taagttaggt
     3901 cataccatca gtacggaaaa aatgcaggaa ttgaactacg aagcagataa taatctagtg
     3961 gaaccatcag tagtagcaca acgtttctta caagaaaacc actattttga agggaagtga
     4021 agcaattgga taaaatgaat gtctttcaac aatttttcta ttatttccag gaaaatggct
     4081 cctatatctt tgcacaattt atccgtcact tcctgatttc tatctatggt gtcctctttg
     4141 cagcagttgt cgggattccg gttgggatca tgatttctag gagacgtaaa ttagcaaact
     4201 gggtgattcg tttggcgaat atcatccaga cgatcccttc tctagccatg atctccattt
     4261 taatcattgg attaggcctg ggagtcaatg tcgtgattgt tactgtattt ttgtattccc
     4321 tcttaccgat catcaagaat acgtataccg ggatgatcca agtagacaaa aacatccttg
     4381 atgtcggcaa aggcatgggg atgactgcta gacaacgact attcatggta gagttaccac
     4441 tctctgtttc tgttatcatg gcaggcataa gaaacgcgtt agttgttgcc atcgggataa
     4501 ccgcgatcgg tgcattcgtc ggtgctggtg gtcttggaga tatcattatc cgaggaacca
     4561 atgcaacaga gggcacatcg attattttag caggtgcatt gccaactgca ttaatggcga
     4621 tcatcacgga ctggctttta ggtattttgg aaagacggct agatccagcc agccgtacat
     4681 cacgctgatg ttattgtaaa aaacaaaagc ttctgcgacc atttgttggt cgcaaaggct
     4741 tttttagttc tgtcattttt aaggcaataa tccactctga ttcttccctc cttatgggca
     4801 aagagttgct tttcttagct atttatccat tccgtatact ccaacttcat actgccaacg
     4861 ggttcatatc tgcatccacc gactaagttt ttttcttatc cgctaaggca ttttgccaat
     4921 ccattttccc atcactcgtc atggaattca taccacatga tctctaaata ctcgtctgct
     4981 tgttctttga attgggcatc aattcttaca tcctttggcg tggctttcat ttaagccttt
     5041 tccatcagtc ctcgattgtt cgatgccttc agctgcatca tcaaaactgg tgactgccgt
     5101 atcggtaact tcgatcatct tttatacaat cgggaacttg ccatcctcat ccttggctaa
     5161 aaacatatct agccattcca gcttctcgcc atgggaggtt tgcggttcct aaaaccggta
     5221 cacgattctt atggactgca tccgtcgcaa ctagacttgg cgatacgatg atccttcacc
     5281 agaagagcac ccccgtaaac caattgatcg atatattgcc aataagaaaa gacattggcg
     5341 taaaagatat cgatccctcg tgatgcattg ccgttgatac tgctattcat ggccgaaagc
     5401 gccacgactt taacttcttc cgtttgagtg acattcatgt tcggcaatgt cgctttggat
     5461 acccgctctg ctaaaggaac gacactggta ttgtatttcg tatctgtatc ttttccaaaa
     5521 gaccatgcca acgaatcctc tgggaaccaa taagacgact ccggttgatt gtccattgct
     5581 tttttcaaca tacttttggc tgtttctcga taaacgacat ttccaattgt cttcgcctca
     5641 ctttggcgat aatcgatggt cgttgccact gccaacacta acaacgatgc tccaatttta
     5701 ctgattttcc ttgtcacact tcttcctcct tgttttacat aaacccgtca acattccatt
     5761 cctaaactca aacaatgacc cttcaaaggt ggagatatag gaacaaatta aagaaatcat
     5821 gcaataaatc caagaaggtt ggttttagaa caaaaaaaga gtctcctttt tggggagact
     5881 ctttgttaac tatctaaaaa ggttggctct tctcacttca ctcataatgt gtccaggcag
     5941 aataaatttc tacaacttta ttttcctcat caactttgta aaccactcga tgctgtctat
     6001 tcagcctgcg tgagtatctg ccttcatgtg taggtctcag cttttcaaaa gactgcgtgg
     6061 gcatatatgg atcttccttc aatgtctgaa tcacttcttc aaattgtttc tttaaattcg
     6121 tttgcttgat ttttcttaaa tccactttcg cagagttttt gattgcgact gtatagttac
     6181 tcatcaaaga gcttcccaat caatatcatc gatattcgta aagctactgt cgtctttttc
     6241 gcggtctcgt actttatcta aagtacctgt ttgctcaaga aaaagggttt cttgaatcgc
     6301 tctccagtct tccagcccaa tcaatacagc attgtttcca ctacgatcac taataatctc
     6361 gatttcagta tgattttcat ttacctcttt caataactga taaaaatttt tacgagcagt
     6421 gctaggattc atcgttgtat tagccattgt ctctcctcct ttttctgata taattatagc
     6481 gtacttgatt aagtacgtca aaaaaataca ataaagcact taaattcagc aaacttttcc
     6541 tcttttttac atagagaaaa agaccccttt ttagggagga tctttgtcca cgctcacttc
     6601 ttactccttt acgactagcg gtagccaaac gtaaagtaat tggtaacaac gtatcatctt
     6661 tagcaaaggt cgaatccaaa gcctgtgagt ctatgcaaca acaccaatac acgaaggttc
     6721 ctcgttgcag tgtgacttga ttgatatctt gaataacctg aggatacgca cgaaagattt
     6781 gtaacggtta ttcaaaactg attttggccg tcaagtcttc tactgcctca aaaatgattg
     6841 cctctttcgt ctcctgtcat tcatgttcac tatcgatttg atacttgctt agaccgttgg
     6901 gtttgtgaat caccaattaa aaatggcact gagttatggt aacaaaaaat ggtcacttga
     6961 cgaggctgag attcctactt atgaagacac atggcactta agagtcgagg taaaggaaga
     7021 agctgaaaat ataggaggct gtacattatt tggcaaagga ttcggaaatt atgatcaaga
     7081 catcaaaatc aaaatgtttt acagctaaat aggaagaata ataacatttc atacgctgtt
     7141 cccatcttta atggcttata gagggcacct ttagctgaga ataagacaaa acagaccctc
     7201 tagcttcaat taagagctag agggtctgtt tttgatttta aaacttggtt tatttcttca
     7261 aatggtagct ataggtgctg acaacgatat tttcacgcca agacaatcgc aatcttaacc
     7321 gcaaacttgt ttggttatgg agaatattct gccagcgtct gtttggtaca aattgaggaa
     7381 tcaacacagt agttgtatag ttttgtttcg ctgcattttt acttacgata tctacataac
     7441 ggataattgg attttcaatc gagcgataag aagagtggac gattgaaaaa cggacatctg
     7501 ggaaatgctt tttaaattct gcttcgattt ctttttcttt ttcgacatct tcgtctagcg
     7561 aaacatgcat cgcaacgaca taatcaccga tcgaacgtgc gtaattcaac gcaccgatat
     7621 ttacccgtgt cacattcccg actaatacaa gaacggtatt cccgtcataa tcatgtagtt
     7681 ttgcatcatt ttctaaacga agctgttctg ctactttttt ataatgatca tggatcttat
     7741 aaaaaatgaa cataacgatt ggcataatga tgaagaaagg ccaaatgtcc cctaaccgat
     7801 agacaaacaa aatcgcaatg attgcatatg agatgaacgc acccgtaata ttggcaatcg
     7861 atttgcttaa ccatcttttt ccttcttttt tccatttgac gaccatccct gtttgagata
     7921 aagcaaatgg aatgaacacg ccgatagagt ataacggaat caagcgttct gttgagccat
     7981 ggaaaataaa cagcaatacg atcgaaccta gcgctagtgt gataatccca ttggaatagc
     8041 ctagtcgatc cccacgatct tgatacatgt gaggcatgaa tttatctttt gccagattgt
     8101 atgcaagaac tggaaaagca gaaaaaccgg tgttagcagc aactgctaaa atcagcgctg
     8161 tagcaaattg aaggacgtaa tacaaaatac catgtccaaa gacagcttta ccaatttgag
     8221 acaaaacagt gacttctttt tcaggaacga tcccatacca atagttgata aatgtgatcc
     8281 ccacgaagaa gaaacctaag atcaatgcca tcatcgtcaa tgtagcagcg gcattttttg
     8341 ctcttggctt cttaaagaat ggtacagcat tactaatcgc ctccacccca gttaaagagg
     8401 aagaaccaga agaaaatgct cgtaaaatca aagcgataga aacacccggc acagccgctc
     8461 ctggaagtgc agtagcttgc aatggcacag cacctgtcac gatattatat aaaccaacaa
     8521 cgatcagtaa cgagatcaca aggataaatg tgtacaccgg aaataatagg aacgatgcag
     8581 attccctcag cccacgaaga ttcagcatca tcagtagcaa aacgattgtc acagaaatag
     8641 cgacttgatg accgtagagt gctggcaccg ctgatgtgat cgcttcagca cctgctgaga
     8701 cagatactgc tactgtcaac atgtagtcga tcaataaaga gccaccggaa atcaagccag
     8761 cattctttcc aagattctca ctgctgacga catatgctcc cccgccatga ggataagcat
     8821 ggatgatttg acgatatgat agcgttaatg aaatcaataa aataataaca aaagcggcaa
     8881 tgggtagcga ataccagatg gctgcagcag acaaagcgac taaaacgaca acgatttgtt
     8941 ccgtaccata tgcaatagat gataacgcat cagacgacaa taatgccaaa gcagcaaatc
     9001 gggttaattt gtgctcatca ttttcagcag attttaaagg cttacctact aacaaccttt
     9061 ttaagtaatc caatttctaa actcctttac acacaatttt acttcaagtt ttatagtcga
     9121 aaatttatag taaacaagat gttatagtac gctcactgac cttaaaagtc aataaacttt
     9181 aagaaaataa ttggaaaaaa acagaaaaat atcaagcgct ttttcaaacg ctttaataca
     9241 gcaaaaatct aac
//
LOCUS       DACGEU010000105         8566 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.108, whole genome shotgun sequence.
ACCESSION   DACGEU010000105 DACGEU010000000
VERSION     DACGEU010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8566)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8566)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8566
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.108"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            99..386
                     /locus_tag="IXR40_002461"
     CDS             99..386
                     /locus_tag="IXR40_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362262.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            802..2340
                     /locus_tag="IXR40_002462"
     CDS             802..2340
                     /locus_tag="IXR40_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HAQ4362263.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            2337..3302
                     /locus_tag="IXR40_002463"
     CDS             2337..3302
                     /locus_tag="IXR40_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4362264.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            3289..4611
                     /locus_tag="IXR40_002464"
     CDS             3289..4611
                     /locus_tag="IXR40_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAQ4362265.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     regulatory      4674..4778
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            4852..5595
                     /locus_tag="IXR40_002465"
     CDS             4852..5595
                     /locus_tag="IXR40_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4362266.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     gene            5610..6602
                     /locus_tag="IXR40_002466"
     CDS             5610..6602
                     /locus_tag="IXR40_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAQ4362267.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            6614..7351
                     /locus_tag="IXR40_002467"
     CDS             6614..7351
                     /locus_tag="IXR40_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4362268.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            7341..8063
                     /locus_tag="IXR40_002468"
     CDS             7341..8063
                     /locus_tag="IXR40_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HAQ4362269.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(8147..>8566)
                     /locus_tag="IXR40_002469"
     CDS             complement(8147..>8566)
                     /locus_tag="IXR40_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HAQ4362270.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQPVVQETVQTEK
                     QAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQLDSSYL
                     NGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT         2767 a         1470 c         1840 g         2489 t
ORIGIN      
        1 ttctttatta tactgactta tactcttact tcaagaggaa aatgaaaaaa aattattttt
       61 ggctgtttct ttttatttat caaataagga gtggaaaaat gcgagcagca gacttattga
      121 caattcttac aaaatcaccc aaaaaaacag agtatcaagg agtttttttg gctcaagaac
      181 aaaaactggt gcctgtgaca atggtccaga taaataaagc aaatcaattt atctttttat
      241 ttgaacacgg caaagcacca cttgctatga aagacatctt tctttttttg atgaagaacc
      301 gtgagaaagc tgtttattat cagtcaaaag aagaactcat tcctctttat ggagtgaaag
      361 agatagaaaa taaagtggtg atataagtaa aaataagaaa acaagacgtt tatgatgtca
      421 aaacaaccat tttttacatt tttggcaaaa aagtgtcatg atacagtata atattcgttg
      481 aacaggccaa taaaggtgtt ctcccccacg agatttctac tttattggct gtttcttttt
      541 attaaaataa aagttgtgtg tgtaaaaaag atatagctga ttccaagtga caatttcgta
      601 tagattttta tggtattcgt agtgaaaaaa cgagaaccaa aaagttgatc cgactttgtt
      661 gcttggattc tttttttgtc agcatattta gaggtatttt tttctttttt ttgttcgtgc
      721 tgtaaggtta aggcaagaca agttagttgg gaaaaaggaa agaaatgttt atacttaaag
      781 aataacagaa aggaaggtcg catgaataat tttatacaaa cattaagtga aagaaaaggc
      841 gagttgctgg aagctgcatt tcaacatctg tccatttctc tcatttcttt gctgattgca
      901 gcactgattg ctattccttt agcgatttgg gcagccaatc ataaaaaaat ggcagaagtc
      961 ttattgcaga tcacgggtgt gctccaaacg attccttcac ttgccttatt aggtttactt
     1021 atcccatttg tagggatcgg aactgttcca gcattgattg cacttgttat ttacgctttg
     1081 cttccgattt tccaaaacac gtatattggt ctagctgaaa ttgacccgtc tattgaagaa
     1141 gcagcggtag catttggtat gtccagaatg agacgcttgc tgaaagtaga gcttcccatc
     1201 gcattacctg tcattatctc aggtatccga actgccttag ttttaatcat cggtacggct
     1261 actttggcag cattgatcgg agcaggtgga ttagggacat ttattttgtt aggtattgac
     1321 cgaaatacac ctgttttgac attgattggt gcgatcagtt ctgccttgct tgcaattata
     1381 ttcagcggac tgattcgctg gttgcagcat aagaaacctc gatattccat cattacttta
     1441 gcagcagtgg tgtgtttatt tggcggcgtt tctttatatc agtctgcctt gtttaaaaat
     1501 gaaaccatca cgattgctgg aaaattagga gcggaacctg aaatcctgat ccaaatgtat
     1561 aaagaattga ttgaagacaa cacaaaaaca gaagttgaat taaaaccgaa ttttggcaag
     1621 acgagttttt tgttcaatgc actggatcaa ggtcaaatcg atatctatcc tgagttcaca
     1681 ggtactgtcc tagaaagctt ggtgaaggta cctgaagcaa tgaaaagtgc tgatttgaca
     1741 aaagaaaaaa catatgacga agcagaagaa ttattgaata agcaattcga tatgacatta
     1801 ttaaaaccaa tggcttacca aaatacgtat gccttggcag tcaagagatc ttttgcgaac
     1861 gaacatcaac ttaaaaagat ttccgatttg gcagctatct ctgatcagat caaagcggga
     1921 ttcacactgg aatttattga tcgttcagat ggatataaag gaatccaaga agcatatggc
     1981 ttgaattttt caagtgtaca aagcatggag ccaagtttgc gttaccaagc aatcaataat
     2041 ggagatgtca atattgtgga tgcctattcc acagatagcc agctcaagga gtacgatcta
     2101 gtgactctag aagatgatcg agggttattc ccagcttatc aaggcgcacc gctgatgaaa
     2161 aaagattttg ctaaagaaca tcctgaaatc gttaaagcac tgaataaatt aagcggaaaa
     2221 ataacagagg atcaaatgat tgatatgaat taccaagtca atgtcgaaaa gaaaaagccg
     2281 acagaagtag cacgaatctt cctgaaaaat gaaggattag taaaggagga agatcagtga
     2341 ctaaattaat cgagttcaaa catgtgcaaa aaaagtatga tggaaagtat gtcatcgatg
     2401 acctaaatct ggcaatcaaa aaaggagaaa tctttgtttt ggttggtcct tccggtagtg
     2461 gaaaaacaac tactttgaaa atgatcaatg gattatctaa accatcagca ggagacatct
     2521 acttcaaagg aaaatcgtta aatgaatata atctgcagaa aatgcggtgg aatatgggat
     2581 atgtgctgca gcaaatcgct ttgttcccga ccatgacagt caagcaaaat attgaagtca
     2641 tccctgaaat gttaggttgg gaaaagcaga aaagagcaga ccgtgtagat gaacttcttc
     2701 aaaaagttgg cttatctcct gatatttatc gagatcgtat gcctagagag ttgtctggag
     2761 gagaacagca acggatcggg atcatccgag ctattgctgc aagcccagat gtgattttga
     2821 tggacgagcc atttagcgca ttagatccga tttcaagaaa ctcattacaa gaattggttt
     2881 tgtccttaca cgaagaattg ggcacgacca tcgttttcgt tacgcacaat atggaagaag
     2941 caatcaagct aggtgatcgt attgcattta tgaaggatgg agaaattatc caatgtgaca
     3001 caccagagca gttattgatg aatcctaaaa acgactacgt tcggcatttc tttgatgaac
     3061 cgaaacagac gaaagagtgg cgagtagaag atttagtcgt caatggatat ttcttaaatg
     3121 aaataccaga aaatgctcgt caacaagttt gctttgatac gcctatgaaa gaagtatatt
     3181 cgcttctttc ggtgtatcca agcattgtga tagtagaaaa gcaaagaagt attgggtcgc
     3241 tgacaagtaa agaaatcttt gcttttttaa gtcgagagga ggaaggaaat gaaaacatat
     3301 gatgcaatca tcatcggttc aggtgtgagc ggcttaagtg ctgcttatgg attgaaagaa
     3361 gcaggtaaaa cagtactagt ggtcgaagaa gatctatggg gcgggacttg tcctaaccgt
     3421 ggatgtgatc ctaaaaaagt cttgttaagt gcagtagagg cacgtaatcg ggtaaaacaa
     3481 ttgagtggaa aaggttttaa cgagatccca actgccaact gggaagaact tcaaaaattc
     3541 aaacgaacat ttacggatcc agtcccagaa agccgaaaaa aacaattagc agaagctgaa
     3601 atcgatcatc tttcaggaac cgctcgtttt ttggatgatt catctattga agtcaacgaa
     3661 gaagtcttcc atgcggatta cttagttttg gcaaccgggc aaagacctac gatcttacca
     3721 gtggagggaa aggaatactt gaaaactagt gcagactttt tatcattgcc tgtactgcct
     3781 aaagaaatca tttttatcgg tggtggttat attgcttttg agctagctac gattgccaat
     3841 gctgcaggga gcaaagtaac cattgtccat cataatcaac ggccattaaa agaatttgag
     3901 gcgtctttgg tagaggaagc cgtccatcaa atggaagcat ctggcattca gtttgctttt
     3961 ggtgttgaaa cccaaaagat catttcagaa ggtactcgct atcgtttagt cggaaaagag
     4021 acggaattag tagcagatat gattttttgt gcgactggga gacagccgaa tacagaatct
     4081 ttagcacttg agcaagcgaa tatcgtcttt gataaacacg gaattgcagt caatgattat
     4141 ctgcaaacga gcaatccaaa aatttttgcg tgtggagata ttgtttcaag gaaaacccca
     4201 aaattgacac cagtcgccac ttttgaagga aattatgtag ctaagcggat aacggatgca
     4261 acaagcgaac ctatcaaata tccgattata cctacgatcg tctacgccag tcctaaactt
     4321 gctgaagtag gagttacaaa aagtcacgcc tcttcgtcag atcaagtggt agagatggat
     4381 cttaccagtt ggttcaccta tcatcgtgtc aatgaaccag ttgctaaggc tgaattgacc
     4441 tttgaccagc aaaattattt gattggtgct gcagtgatta gcgagcaagc agacgaattg
     4501 atcgatgatt tgacactcgt catcaatcaa aaattgacta aaaaagagtt ggatagctat
     4561 atcatggggt atccgacatt ggcaagtgat ctctcctatt tattgaaata atcagcatga
     4621 taactaaagc gcttgttgct ttttccttct tgtgctacac tttaaaaaat gaatacctgt
     4681 ttctggggat gtcgtagacg acatgagagt aagttgtgaa cttagaccca ttgaacctgt
     4741 cagttaatac tggtgaaggg agaaacatag cagacgcttg aagcgggtta ctatgtcgtg
     4801 cccatttcaa gcgttttttg ttattcatat tagaagaaag gaggtaacaa aatgaagaaa
     4861 aatctttatc cagcagtcag tatggcattc attttaatta tttggcagat tgttgtcata
     4921 gtttggaaaa tacctgcctt tattttaccc ggacctgctg ctgtattttc tgcattagcg
     4981 gcagatgcac aagtattact ttcccattct gtcacgacat taaatgaagc agtgcttggt
     5041 ttggtaatag ctagcgttct ttcttttatt actgccttgg caatggatta ttggaagttt
     5101 ttagaaatgt ctttttatcc gttactagtg atttcacaaa tgttgccaat catggtgtta
     5161 gggccattac ttaccctatg gtttggtttc ggtatgcttc caaaagtgat ccttgttgtc
     5221 ttgataagct attttccgat cgtagtttct ttttcggata cattgaggaa agtatcaaaa
     5281 gagcaaatca tctttttgaa aacgatgggg gcagatacag ggaagattta tcgaatatat
     5341 aaaataccag cgggtttatc cggcttcttt tccggtttaa aagtggctgc tacttattgt
     5401 gtcagcggag cagtcgttgg agaatggcta agcgctcaag caggcttagg gtattacatg
     5461 atacgcgtaa aaaacagcta ccagatcgat aaagtttttg ctgcgatcat ttgtgtcatt
     5521 ctattgagtt tattgctgaa tggcgcttgt tcattattga aaaaagggta ttatcgtatg
     5581 ctttatattt tttaagagaa ggggatcaaa tgaaaaaatt atggctttta ttaccgctac
     5641 tgttgctttt atccgcttgt ggcactgcaa aagaaacaag tagcaaacaa gaaataaagg
     5701 atttgaaaaa agtgacactt gttttggatt atgtaccgaa tactaatcat actggcatct
     5761 acctagcaaa agaaaaaggc tattataaag aggctggttt aaatgtccaa atcatcgaac
     5821 caggagataa ttcgacaagt attggtctag taggtgcgga caaagcacaa tttggtgtaa
     5881 gttatcaaga agatgtcact tatgctcacg cagatggaca gaatatacca gtcaaagcaa
     5941 ttgctacagt gatcaaacat aatacttctg gattcgccac cctatcagac agtaacatcc
     6001 attcaccaaa agattttgaa ggaaaaacat atgcaggttg gcaaagtcca agtgaagaag
     6061 ctgtcttaaa agctgtgatg gaaaaagacg gcggggactt ttcaaaactg acaatggtag
     6121 gaagcaatgg agaagggcca gaaagcttag gaaaatcctc agatatccaa tggtactttg
     6181 aaggttggga tatgatcaaa gcaaaagaag cgggtattga actaaactat atcccattga
     6241 aagaattaga tgaacggtta gattactata ctccggtaat tattacgaat gatcaactga
     6301 tcaaaagtga tccagaattg gtacagtctt ttatggatgc cacgaaaaaa ggctatcagg
     6361 aagctattaa ggatccaaat gacagtgcta aactgttgca aaaatatgca aaagaaaatg
     6421 atcggacgtt tttagaagaa tcacaagcat tcttgtcaaa aaattatacg gatgatcctg
     6481 agaattgggg attgatggaa gaaaaagttt ggcgcaatta tacagctttt atgcaggaaa
     6541 acggattgat caagcaagat gtaccttcgc aagaactatt cactaatcag tttataaaat
     6601 aggagtgata gatatgtcaa tccaaatcag ccacttgaat gtagtcattg aaaacctgaa
     6661 aatattagaa gacatccatt tcactatccc taaagatacc tttacatcga ttgtcgcgcc
     6721 aagcggagcc ggtaagtcaa cattgctgaa aactttaaca ggagtccagc ctatgacttc
     6781 tggaacgatc aaagtagacg atcaaaaagt aactggtctc catacagcat ttagttatat
     6841 gccgcaagaa gatatgttac ttccttggct gagcgtctat caaaacgtta cgttatatca
     6901 aaaaatcaat catctaacaa tcaatgaaga acaagtaagg gattatctgg atatctttgg
     6961 gttaaacggc tatgaacatt ttttgccgga acaattatct ggcgggatga agcagcgaac
     7021 ggccttgtta cgaacaatca tgaatccttc ttcttacttg cttcttgatg aaccatttgg
     7081 agcgttagat gctatgacca gagggcagat gcaagactgg atgttgaagc tgcctaaaaa
     7141 agcaaagcgg actactttac ttgtgacgca tgatatcgaa gaagcaattt atttatcaga
     7201 caggattctt gtgctttccg cccgtccggc acatgtgatt gctgagattc aagtgcctga
     7261 aaaacgacgg tcacgtgaat ggctactgca gcaatcagag ttgaagcaaa cgatttatca
     7321 gttattggca ggtgaattag atgttaagtg atgctcattg tcatttagat gggagtcaga
     7381 gtttagcact ccttcagcag gaacacacga ttttgacgat catcaattgt gattcgccag
     7441 aagaatggaa ggaaaacaga cagcttgcag caagtaagac tcaagcctta agttacggta
     7501 tccatccttg gaaagcagat agctatacgt ttgaacaagt tgagcctttt ttgaaaaaag
     7561 caaggatcat cggtgaaata gggttagata atatttggac gaatgtaccg atgactacac
     7621 aaaaaaaagt atttgagcga cagcttgctt ttgcagccat aaatgagaaa cctgttgtac
     7681 tgcacacaaa aggatgcgaa aaagagatct taaattatat ccaagcttac cctaatcact
     7741 atttgatcca ttggtattct tctttggact atcaacaaga ctatattgat ttaggctgtt
     7801 atttcagcat tggtcttgat ttgaaaaaga atccagcagt ctggcaacta gctaaagcag
     7861 tcccaatcga ccacttactt attgaaacgg atggactaca tgcagcagag tgggctttag
     7921 gggggatttt ttcagaaaaa gattatgtct cactgcttga agaacagtta aagacaatcg
     7981 ctgagatcaa agagctatca gttgaagaag ttaaaaaaaa tacttatcaa aacttggaac
     8041 gtttcattag attaggtaaa taaaaaagag atgtgacaca actagtgtcg cacctctttt
     8101 tggctttctt tgtataaaag taaactgttt gattaataaa tgaatcttag taccaaccgt
     8161 ttgcttccca gaatgctttc gccgcttccc aagaaccata acgtgaagta acatattgtt
     8221 ctgctactct ttcttggttt gcagcagagt agtcaccatt taagtaagaa gaatctaatt
     8281 ggtaacgtcc gatgtaacgt ccgttcgttg ctgtgtaaga accgcttgat tctttttgtg
     8341 cgatccattc ttttgcagag cttgtgcttg ctggagtagc agcagtttct gttacagcag
     8401 gagcaggttg tgtttcagca acaggcgctg cttgtttttc cgtttgaacc gtttcttgta
     8461 caacaggttg ttcagcttgg actggtgctt cttgaacggc tgcttgaggt tcagcagctg
     8521 cttgtgcaga gccttctgtt gggattgtta attgttgtcc tgagta
//
LOCUS       DACGEU010000106         8547 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.109, whole genome shotgun sequence.
ACCESSION   DACGEU010000106 DACGEU010000000
VERSION     DACGEU010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8547)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8547)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8547
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.109"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(204..1346)
                     /locus_tag="IXR40_002470"
     CDS             complement(204..1346)
                     /locus_tag="IXR40_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAQ4362271.1"
                     /translation="MRKIANVYKDRKRGTWFFSATLGQDRFGKRIQVTRRGFKTQGEA
                     RRGLEELKQSFSDSQGIYLQGITFHDFYREYFFPWYKLGTVEKTYMKTDHILQRALDF
                     FGEMQVVKIRPIHIQEFQQFLSKIHVVKKGIEQPLSPNYIKQIFNKLRVVFKRAIVLE
                     IIEENPVDTIGKIKTQRPQVEFWTVDEFKKVYNSVYHGDFYEEFYKRLMRFIFVTGVR
                     SEELLALQWKDFDLINGRCSVNKSIYIRTRQDYEFAETKNTSSIRIISLDRQTVEDLK
                     TWKKTQQSIGKNIELVFSFDGLPPSPRTILSRIKKLAEIAGVKPIHMHGLRHSHVAFL
                     IEHNKNIYAISKRLGHASIKTTLDKYGHLYPETNQALANEITRFDI"
     gene            complement(1351..1536)
                     /locus_tag="IXR40_002471"
     CDS             complement(1351..1536)
                     /locus_tag="IXR40_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HAQ4362272.1"
                     /translation="MKTATRKDLINLGFSQYYANKIFKECKELLVEKGYFFYRNSKIK
                     RIPISILEEVLHISWEE"
     gene            complement(1890..2135)
                     /locus_tag="IXR40_002472"
     CDS             complement(1890..2135)
                     /locus_tag="IXR40_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002412373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAQ4362273.1"
                     /translation="MVDKSKKRQYLLVPLSIILSALEGDPISIKMILKHYHSYMAKLC
                     LTNGFNEVGQFVTYVDEYMISQLEIKLIEAILKFKIN"
     gene            complement(2129..2530)
                     /locus_tag="IXR40_002473"
     CDS             complement(2129..2530)
                     /locus_tag="IXR40_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAQ4362274.1"
                     /translation="MQQHYNDISIQHQFDAYCKKVLRNEAKSIRKRNANIKDNEEPLA
                     DSNEGRYSQTHFDEQDVYFLFGMEILISDQKLSAAIDQLSEIRRKIILLYYFAGFNDA
                     EIGKILNMSTSGIWYQRKKAVEQLKMGYDLW"
     gene            complement(2717..4525)
                     /gene="uidA"
                     /locus_tag="IXR40_002474"
     CDS             complement(2717..4525)
                     /gene="uidA"
                     /locus_tag="IXR40_002474"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003479936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HAQ4362275.1"
                     /translation="MLYPIMTETRQVIDLSGLWRFKLDTNDDLQEELALEPINEKESY
                     PISVPSSYNDLFETENIRNHVGWVWYEKEVTLPKRLLEERLVLRFGSATHEAKVFLNG
                     KFITQHKGGFTPFESEINRFVKDGNNRITVAVNNIIDDSTLPVGIMKETVQENGDIKK
                     ENLVNFDFFNYAGIHRPVKLYTTPKDYISDITINTRITDLDASVEFNIDTEWTGKILI
                     AIYDEEAQLVAEAEGKKGMIQLKNPIFWEPLDAYLYSMKISLIDDNKVIDTYTEEFGI
                     RSVQVTNGKFLINNKPFYFKGFGKHEDSYVNGRGLNEAVNIKDFNLMKWIGANSFRTS
                     HYPYSEEIMRLADREGIVVIDEVPAVGLHLNFMATLLDDNVEKHNTWKEIRTENSHKT
                     VIKELIERDKNHPSVVMWSIANEPDSDSEGAKEYFEPLVELTKELDPQKRPVTIVTYL
                     KSTPDVCKVGDIVDVLCLNRYYGWYVSGGDLAHAKYLLKKELDGWMERCPDTPIMFTE
                     YGADTVAGFHDTVPTMFTEEYQVAYYEANHEVIDTCENFVGEQVWNFADFATSQGILR
                     VQGNKKGIFTRDRKPKMIAYYLQKRWSSIPNFSYKK"
     gene            complement(4548..6314)
                     /locus_tag="IXR40_002475"
     CDS             complement(4548..6314)
                     /locus_tag="IXR40_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-hexosaminidase"
                     /protein_id="HAQ4362276.1"
                     /translation="MTIKVDLRKKPYNLDEDAISWIEETIDSMTLEEKIGQLFVNMGS
                     SRDKNYLSNMVNQYHIGAVRYNPGTADEVYDQNYILQTESKIPLLIAANTEAGGNGAC
                     TDGTEVGVEVKIGATNDAKYAYELGRVSGIEASAIGCNWSFAPIVDINRNWRNPIISS
                     RSFGQNPDKVLELSLAYMKGIQESGILPAAKHFPGDGIDERDQHLSFSINSLGTEEWD
                     NSFGKVYSGLIEAGLPSIMAGHIHMPAYSKHFNPDLKDEDLLPATLSKELITDLLRGK
                     LGFNGLVVTDASHMLGMTGAMKRSELLPTSIAAGCDLFLFFNDPDEDFNYMMEGYRKG
                     IITDDRLLDALKRILGLKAKLGLHKKAKEQFLLPKQEALEKIGLIENKSIFKEVADQA
                     ITLVKDKQDIWPIVPEKYKRILLVDVHGVKGGFGEVVAGNRPQAIDLLKQILSAKGFE
                     VEKYISPEEELKGLSQEEKIKNIAGIYAAKRPIKNLTKKYDLIINIANVNPGTVQRIV
                     WPASKGTPDIPFYIHEIPTIFVSVQCPFHLADVPQVKTYINTYDGKQETLEILVDKLM
                     GLSEFKGVSPIDAYCGLKDTFI"
     gene            complement(6327..7121)
                     /locus_tag="IXR40_002476"
     CDS             complement(6327..7121)
                     /locus_tag="IXR40_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HAQ4362277.1"
                     /translation="MNNWIFCIDSDGCVMDTMTYKHNLFFGPIAAEIFDVHHREKFLQ
                     DWNNINLYSETRGINRFLGLVKTLEKNDVTSINRLKHWVSLTKELSNPSLKREIEYSQ
                     SEDLLKALKWSEEVNQQISQAKGLDKPFLSARDTIKALKKYGKIIIVSSANKEAVQEE
                     WERHELLSLVDELCCQDKGKKEDIIRSVIENGCDLDKILMIGDSPGDLEAANKNKVFF
                     YPILVNKEKESWENLRTDVLFKCLSGDYVDIEQKYIDTFWKNLTNK"
     gene            complement(7131..8507)
                     /locus_tag="IXR40_002477"
     CDS             complement(7131..8507)
                     /locus_tag="IXR40_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAQ4362278.1"
                     /translation="MERKFGIRDKIGYMFGDFGNDFTFIFASSFLMIFYTKVLGISGA
                     AVGTLFLVARFIDAVTDVTMGRIVDRSKATKQGKFKPWILRMSGPVALASFLMYQTSM
                     ISASMSVKVVYMYVTYILWGSIFYTSINIPYGSMASAITSITEERTMLSTFRNVGATL
                     ASLVIGVLTPLFIYTRDDSGAQIVRGGSTFTIVAGIFSICALICYLICYKLTTERVRI
                     DQSQYKVSLLKSLKGLVKNRALLSIIGAAIFLLLAQLLIMSMNNYVFPDYYNDAQGIV
                     LMNFINPILVLIVVSPLTLFLSKKYGKKELASVGMFFSAIVYLILFLIKASNMYVFLI
                     LSSVGYMGLGVFNTVIWANITDVIDDQEVKSDQREDGTVYAVYSFARKIGQALAGGVG
                     GWTLSIIGYDSLANVQTGDVLEKLYNASTLIPSICFLIVGLILFFLYPLSKDKVLENC
                     ELLKQKHK"
BASE COUNT         2762 a         1661 c         1064 g         3060 t
ORIGIN      
        1 aaaaaccacc ggtggcaaac cggtggcaaa tccatgtaaa catggtttat tttttacact
       61 gttttcaaac aaacccttgc tatttcttcg gttcgtcctc gtccattttc gataccgaca
      121 gctagcttat aacccaaggt atatcaacat aaaaaaataa aaataggcta tgacagcagc
      181 gtgacagcaa aaaagatgga aagttaaata tcaaacctcg taatttcatt tgcgagtgct
      241 tgatttgttt ctggatataa gtgtccatat ttgtccaaag tagttttaat agaggcatga
      301 cctagacgct tagatattgc atagatattt ttattatgtt caattaaaaa ggcaacatgc
      361 gagtgtctta atccatgcat atgaattggt tttactcctg caatttcagc tagttttttt
      421 attctgctta aaatagttct tggagatggc ggtaatccat caaaagaaaa aaccaattct
      481 atatttttcc caattgattg ttgagttttt ttccatgttt ttaaatcttc aacggtttgt
      541 ctgtctaacg aaattatccg aatacttgat gtattttttg tttcagcaaa ttcataatct
      601 tgtcttgtac ggatgtaaat tgacttattt acgctacatc tgccatttat taagtcaaag
      661 tctttccatt gtaacgctaa gagctcctca ctccttacac ctgtaacaaa aataaaacgc
      721 atcaaacgtt tataaaattc ttcataaaaa tccccgtgat aaacactatt atatactttc
      781 ttaaattcat caactgtcca aaattctact tgaggacgct gagtttttat tttacctata
      841 gtatctacag gattttcttc aataatttca agtacaattg cccttttaaa aactactctc
      901 aacttattga atatctgttt aatataattt ggtgataatg gttgctcaat gccctttttt
      961 acaacatgga ttttcgataa aaactgttga aattcctgta tatgaattgg tcgaatcttt
     1021 acaacctgca tttctccaaa aaaatccaat gcacgttgta aaatatgatc tgttttcata
     1081 tatgtttttt ctacagttcc caacttatac caaggaaaaa aatactctcg ataaaaatca
     1141 tgaaacgtta ttccttgcag ataaattcct tgtgaatcag aaaaactttg ttttaactct
     1201 tcgagtcccc ttctagcttc tccttgagtt ttgaagcctc ttctggtcac ttgaattctt
     1261 tttccaaagc gatcttgtcc taaagttgca gaaaaaaacc aagtgcctct ttttctgtct
     1321 ttataaacat tcgcaatttt cctcatttta ctattcctcc caagaaatat ggagaacttc
     1381 ttctaaaatt gaaataggaa ttctttttat ttttgaatta cgataaaaaa agtatccttt
     1441 ctcaactaaa agttctttac attccttgaa gattttatta gcatagtact gagaaaaacc
     1501 tagattaatc aaatcttttc gagtagctgt tttcattata gcaccttcct tacttttttt
     1561 catttatttc tatcagctgc ttttgtcaaa agcacatagg aatttcacct ctccccaagt
     1621 ttacggcgag ccttacggaa gtatcattat cccaacttta aatcatcgct ttttattgac
     1681 tataaaaatt attttagaat atttatcgct ccttctttac agcaagaaat catggcgcaa
     1741 ctaaaatatg ctccttaaag tgttaacgta ctgatagaat ctatttaatt ttcaatgaac
     1801 aataggtttt ctacctaaaa gaatctacta attccttaac tattagaaga ttcttttaaa
     1861 cagaaaaagt ggaaagggga tttttttaat tagttaattt taaattttaa gatcgcttct
     1921 attaatttaa tttctagctg acttatcata tattcatcta cataggtaac gaattgacct
     1981 acctcgttaa atccatttgt caaacataac ttagccatat aagaatgata atgtttgagt
     2041 atcatcttga tcgaaattgg atctccttct agagcagata agataatgga tagtggaact
     2101 aataggtact gccgcttttt agatttatct accataggtc ataccccatt ttcaattgtt
     2161 caactgcctt ctttcgttga taccagatac cacttgtgct catattgaga attttaccga
     2221 tttcagcatc attaaaacct gcaaaataat aaagtaggat aatctttctt cttatctccg
     2281 ataactgatc aattgctgct gataactttt gatctgaaat taatatttcc attccaaata
     2341 agaaatagac atcttgttca tcaaaatgag tttgggaata cctgccttca tttgaatctg
     2401 ccaatggttc ctcattatcc tttatgttag cgtttcgttt tcgaatagac ttagcttcgt
     2461 ttcgtaatac ttttttacag taggcatcaa attggtgttg tatagatatg tcattgtaat
     2521 gttgttgcat gataatatgc tcctttttcc ccctttccac taatacaaca atcagaaagc
     2581 cccttttttt cgaaaaaact agaaaaaaaa cataaaaata tttatcattc tttaaacaga
     2641 aaatctttct ataaaaaaca aaaaaaaacg attaggctag gctaatcgtt ttttgaacat
     2701 tcttaaaaaa tccaaattat tttttataac tgaaattggg tattgatgac catcgtttct
     2761 gtagatagta agcaatcatt ttaggttttc tatctctagt aaagattcct ttcttatttc
     2821 cttgcactct taaaatccct tgacttgttg caaaatctgc aaaattccac acttgttcac
     2881 caacaaaatt ttcacatgta tctattactt cgtgatttgc ttcgtaataa gccacttgat
     2941 actcttctgt aaacattgtt ggtactgtat catgaaatcc agctactgta tctgctccat
     3001 attctgtaaa cattattggc gtatcaggac atctttccat ccatccatct agctcttttt
     3061 tcaacagata ttttgcatgt gccagatccc ctcccgaaac ataccaacca taataacgat
     3121 ttaaacataa aacatcgaca atatctccta ccttacaaac atctggcgtt gattttagat
     3181 aagtaacgat tgttacaggt cttttctgcg gatcaagttc tttagttaat tcaactaaag
     3241 gttcaaaata ttctttagca ccttcggaat ccgaatctgg ttcatttgca atagaccaca
     3301 ttacaacact tgggtggttc ttgtcgcgtt ctatcaattc cttgatcacc gttttatgag
     3361 aattttctgt tcgtatctct ttccacgtat tatgtttttc cacattatca tctaataaag
     3421 tggccatgaa atttaaatgt aaccctactg caggtacttc atcaataact acaatacctt
     3481 ctcgatctgc taatcgcata atttcttctg agtaaggata atgtgatgtt ctaaaagaat
     3541 tagcacctat ccatttcatt aaattaaaat ctttaatatt tacagcctca ttcaaaccac
     3601 gtccattaac atacgaatcc tcatgcttac caaatccttt aaaataaaaa ggtttattat
     3661 taatcaaaaa tttgccattg gtaacctgaa cactgcgaat accaaattct tctgtatagg
     3721 tatcgatcac tttattatca tcaattaaac taattttcat actatataaa taagcgtcta
     3781 gaggttccca aaaaattgga ttcttaagct gaatcattcc tttctttcct tcagcttcag
     3841 ctacaagttg agcctcttcg tcatatatcg ctattaagat ttttccggtc cattctgtat
     3901 cgatattgaa ttctacactt gcatccaaat cagttattct tgtattaata gtaatatcac
     3961 ttatatagtc tttcggagtt gtatataact taacaggtct atgaatacct gcataattga
     4021 agaaatcaaa attaactaag ttttcctttt ttatatcccc attttcctgt actgtttcct
     4081 tcataatccc cacaggtaaa gtactatcgt caataatatt gtttacagca actgtaattc
     4141 gattattccc gtcttttaca aaccgattaa tttcagactc aaatggtgta aacccacctt
     4201 tgtgttgagt aataaacttt ccattcaaaa aaacttttgc ttcatgtgtt gcagatccaa
     4261 aacgaagaac taatctttct tctaataatc ttttaggaag agtcacttct ttttcatacc
     4321 acacccatcc aacatgattt ctaatgttct ctgtttcaaa taaatcatta taagaagagg
     4381 gaactgaaat cggataactc tctttttcat ttattggttc taaagcaagt tcttcctgta
     4441 agtcatcatt tgtatctaat ttaaatctcc agagaccgct taagtcaatt acttgcctcg
     4501 tctctgtcat aatgggatac aacatataaa ccactcctat ctaaatatta aataaatgta
     4561 tcctttaaac cacaataagc atctattgga cttactccct taaattcaga aagacccatt
     4621 agtttgtcca ccaatatttc taaagtttct tgttttccat cataagtatt aatataagtc
     4681 tttacttgag gtacatcagc caaatgaaac ggacactgta cagatacaaa aattgttgga
     4741 atttcatgaa tgtaaaacgg tatatccgga gttcctttac ttgctggcca gacaattcgt
     4801 tgaactgtgc ctggattaac attagctata ttaatgatca agtcatattt tttagttaaa
     4861 tttttaattg gtctcttagc agcatatatt ccagctatat ttttaatttt ttcttcttgc
     4921 gataatcctt tcaattcttc ttcaggtgaa atgtattttt caacttcaaa tccttttgct
     4981 gacaaaatct gtttcaataa atcaatggct tgaggtctat ttccagcaac tacttcacca
     5041 aacccacctt ttaccccatg tacatctact agtaaaatcc ttttatattt ttctggtaca
     5101 ataggccaaa tatcttgttt atctttaact aatgtaattg cttggtcagc cacctcttta
     5161 aaaattgatt tattttcaat taaaccaatt ttttccagag cttcttgctt aggtaataaa
     5221 aattgttctt ttgctttttt gtgtaatccc aatttagctt ttaaccctaa aattcttttt
     5281 aaggcatcta ataaccgatc atcagtgata attcctttac gatagccttc catcatataa
     5341 ttaaagtctt catctggatc attaaaaaat agaaatagat cacatccagc tgcaatagaa
     5401 gtgggcaata attctgatcg tttcattgcc ccagtcattc ctaacatatg actagcatca
     5461 gtaactacta atccattaaa tccgagtttt cctctaagta agtcagtgat taattctttt
     5521 gataaagttg caggaagtaa atcttcatct ttcagatcag gattaaaatg ttttgaataa
     5581 gctggcatat ggatatgacc tgccataatt gaaggtaatc cagcttctat taagcctgag
     5641 tatacttttc caaaagaatt atcccattct tccgtaccta aactattaat actaaaagat
     5701 agatgctgat ctcgttcgtc aataccgtca ccagggaaat gtttagctgc aggcaaaatt
     5761 ccactctcct gaataccttt catataagct aaactaagtt ctaaaacttt atcagggttt
     5821 tgtccaaaag atcgactaga aatgatagga tttctccaat ttctattaat atctacaata
     5881 ggagcaaaac tccagttaca tccaatagcc gatgcttcaa tcccagaaac tctccctaat
     5941 tcataagcat atttcgcatc atttgttgca ccaattttta cttctacacc aacttcagta
     6001 ccatctgtac aagctccgtt accacctgct tccgtattag cagcaattaa tagaggaatt
     6061 ttactttctg tttgtaagat atagttttga tcatatacct catcagcagt tcctggatta
     6121 tatcgtacag ctccaatatg gtactgattg accatattac tcaagtaatt tttatcacga
     6181 ctagatccca tattaacaaa caattgacct attttttctt ccaaagtcat agaatcaatc
     6241 gtctcttcaa tccaagaaat agcatcttca tctaaattat atggtttttt tcgtaaatct
     6301 acttttatag tcattttctt tctcctctac ttattagtaa gatttttcca aaaagtatct
     6361 atatattttt gttcaatatc tacataatct cccgataaac atttaaataa aacatcagtt
     6421 cttaagtttt cccatgattc tttttcttta ttgaccaaaa taggataaaa gaaaacttta
     6481 tttttatttg cagcttctag atcaccagga gaatcaccaa tcattaatat cttatccaaa
     6541 tcacaaccat tttcaattac acttcgaata atatcttctt tttttccttt atcttgacaa
     6601 cacagttcat caactaatga taataattca tgtctttccc attcttcttg aacagcttcc
     6661 ttattagctg agcttacaat aattatcttc ccatattttt tcagagcttt tatagtatct
     6721 ctagcactta aaaagggttt atctaatcct tttgcttgac taatctgttg attgacttct
     6781 tccgaccatt ttaaagcttt taataaatcc tctgactgag aatattctat ttccctcttc
     6841 aaagatggat tagacaattc ttttgttaga gatacccagt gctttaatcg attaatcgat
     6901 gttacatcat ttttttctaa tgttttaact aaacctaaaa atctgtttat tccacgagtc
     6961 tctgaatata aattaatatt attccaatcc tgtaggaatt tttctctatg atgaacatca
     7021 aaaatctctg cagcaattgg tccgaaaaag agattgtgtt tataagtcat cgtatccata
     7081 acacagccat ctgaatcaat acaaaatatc caattattca tatttctctc ctatttatgt
     7141 ttttgtttta aaagctcgca attttctaag actttatctt tagataatgg ataaaggaaa
     7201 aataaaatta atcctacaat cagaaaacaa attgatggaa ttaatgttga agcgttatat
     7261 aacttttcta aaacatctcc cgtttgtaca tttgctaaag agtcatagcc tataatagaa
     7321 agagtccaac ctccgacgcc tccagctaga gcttgaccta tttttctagc aaaagaatat
     7381 accgcatata cggtcccatc ttctctttga tcagacttta cttcttgatc atcaataaca
     7441 tcagtaatat ttgcccaaat aacagtatta aacacaccca aacccatata gccaaccgaa
     7501 ctaagaatta agaatacata catattacta gcttttatca aaaataagat caaatatact
     7561 attgctgaaa agaacattcc tactgatgcc agttcttttt ttccatattt tttacttaaa
     7621 aacaaagtta aaggcgaaac aactattaaa accaaaatag gattgataaa attcattaaa
     7681 actattccct gtgcatcatt atagtaatca ggaaatacat aattattcat actcataatt
     7741 aataattgag caaggagtaa gaaaatagcc gcaccaatta tagaaagtaa tgccctattt
     7801 ttaactaacc cttttaaaga ttttaacaat gaaactttgt attgagattg gtcaattctt
     7861 actcgttcag tagttagttt ataacatatt aaataacaaa taagtgcaca tatcgaaaat
     7921 attcccgcaa caattgtaaa agttgatcca ccacgaacta tttgagcgcc tgaatcatct
     7981 cttgtataaa taaataatgg tgttaataca ccaatgacca aacttgctaa agtagctcca
     8041 acatttcgga atgtcgatag cattgttctt tcttctgtaa tagaagtaat agctgatgcc
     8101 attgatccat aaggaatatt tatagatgtg taaaaaatac tcccccataa tatatacgta
     8161 acatacatgt atactacctt aacgctcata gaagctgaaa tcatagaagt ttgatacatt
     8221 aaaaaacttg ctaaagcgac tggaccactc attcttaaaa tccacggttt aaacttaccc
     8281 tgcttagttg ctttcgatct atcaacaata cgccccatag ttacatcagt aactgcatcg
     8341 ataaatcttg ctactaaaaa taatgttcca acggcagctc cgcttatccc caatactttt
     8401 gtataaaaga tcattaaaaa agaactagca aaaatgaaag taaaatcgtt tccaaaatct
     8461 ccaaacatat atcctatttt gtctcttata ccaaattttc tttccataca attctctccc
     8521 ttctgttgtt aagcgttttc attctga
//
LOCUS       DACGEU010000107         8473 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.110, whole genome shotgun sequence.
ACCESSION   DACGEU010000107 DACGEU010000000
VERSION     DACGEU010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8473)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8473)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8473
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.110"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            <1..895
                     /locus_tag="IXR40_002478"
     CDS             <1..895
                     /locus_tag="IXR40_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362279.1"
                     /translation="FKAEGIDFIFWSGVISYMSGSVFYLIVSYGLNGLISYIKSLITG
                     ETNTANFAMEVHDLTFAMGVFFLYYVFFENKNTKKHKIKIIVSLILIFMGLKRIELLA
                     LSGAILVYYVLLKWGKKIQIRALVCTICATVISLVFIYIIDTGILALLMSNLGITDDG
                     ARLSFYLYSSKFYELGLGYVGTGWTWFSKYFFNLYLSHFRLNGGRIAASLHSDILTIY
                     IEVGCIVFIIWMFWLFFVKPIRLTKKFGLKTGECVLLLTIYMFILYLTDNTLTYPDTQ
                     MIFLLVPMIVSWVDNQQRISE"
     gene            979..2067
                     /locus_tag="IXR40_002479"
     CDS             979..2067
                     /locus_tag="IXR40_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362280.1"
                     /translation="MKKILVLANTYYQIIVAIQMKNTIFSDEYVEIIISDHSKNTKEI
                     AKKIEEKKVFDGCHYLESKSFDDNIGYFQKIKDCLQISCGKSNRYAYYLKNCKSEYFD
                     EFICFSMGEVWLEGIYACLYRNNKNVQVSILEEGILSYGVDIIPTARTKAIAVLNYLK
                     KRTPLYNKSYNFYCFFPNIYTGRENTIQIPLVTAGSRTALQLSDIFNPMIDIYKEKKY
                     IFFTSVYDFEGGEPVGEYELVCKIADLVGKDNLIVKTHPRDVRTIYKDNGFIEDKNSS
                     IPWEAIQLSGDFNDKIFMTINSGSVISGSTMSAKPVRTYYMYKLCNIEGNPSCKKNAY
                     DIERLLKQKTMKNILKNVKIAESLDDIL"
     gene            2064..3485
                     /locus_tag="IXR40_002480"
     CDS             2064..3485
                     /locus_tag="IXR40_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HAQ4362281.1"
                     /translation="MSKTKYLIKNMGILTISNFSSKILVFLLVPLYTSVLSTTEYGTY
                     DLTISTATLLFPILTLNIVDAVMRFLMDKDKNKKNIASIAIKVIFLSVIVFGSVMYLL
                     NITKLWQDVYGLEKYIFLYYISYVWNQFLIQFAKGLEKVKAMGIAGIISTIVTIIANI
                     FFLLILKWGLIGFFIANILSQIISATYLSVLVRIWEYIDFEAKDPQLKREMLNYSIPL
                     IATVVGWWINSTADRYVVSFIVGVSANGLLSVAYKIPQIINTLQGIFIQAWQISAIKE
                     YGDNETAKFYGNTFVMINLLMCITCSSLIILTRPFSHILYAKDFYEAWKYVPFLLIAN
                     VLNCASGLLGPILSAKKDSKSMMWSAIIGALVNVIMSVVLVYKIGVQGATIATVICSY
                     VIYVVRKRAVGKDIFIKHYHIVVESWGLLFVQAIIEIYFKNYVIEIIIMIILIIINIS
                     YIKQLCYRGRNIISMIKSREHKR"
     gene            3578..4237
                     /locus_tag="IXR40_002481"
     CDS             3578..4237
                     /locus_tag="IXR40_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HAQ4362282.1"
                     /translation="MKIVAIVPMKLNNKRLPQKNTKAFTNGKPLCYYILSTLLKVKQI
                     DKVYVYCSNPDIKEFIPEGVTFLKRSSSLDQDTTSITQVLAGFTKEVEADVYVMTHTT
                     APFISEKSIEKGLDAVLTGEYDSAFAAKKLQDFLWKDGEPFNYELDNIPRTQDLPPLY
                     EETSGFYIYNRNVMTELHRRIGKKPCIVEVGEIESVDIDEAEDFMIADAIYNHLILQG
                     S"
     gene            4256..5839
                     /locus_tag="IXR40_002482"
     CDS             4256..5839
                     /locus_tag="IXR40_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxy-3-methylglutaryl-CoA lyase"
                     /protein_id="HAQ4362283.1"
                     /translation="MNNVQILDCTLRDGGYCNNWEFGFDNTKKIISGLIESGIEIIEC
                     GFLTNKTVYNKNVTKYTTLEELAQIIPEKREGKLFVAMMNYGEYNIEDLPDYDGSSID
                     GIRIAFHKKNCNEALKLCREIKKKGYLVFVQAMVSLNYTDEEFLAVIKNVNQFKPYAF
                     YIVDSFGMMKGKDLTRLFYMIEHNLEKDIQIGFHSHNNMQLAYSNAQKLITVQTNRSL
                     IIDSSVYGMGRGAGNLNTELFVEYLNDNAGKKYQLKPLLYIIDEILNSFYQKSYWGYS
                     LPNYISAVHNAHPNYASYLSYKNTLTIEAMNEIFEMMDEEKKVSYDKQYIEDLYYKYM
                     ETGKIQEEYMEELRKFLSDKKILLIAPGKSSVDEVERIKEFVTKEEVVIISVNFEYSH
                     IDIDYVFLSNLRRFHELPKESRTKCIVTSNIQASDVYLRTSYKKLLSEREVVRDNAGL
                     MAIRFLADMNVDEIFLAGFDGYSHNEDENYGEQSMEIITKFALLDAMNVQMRDELSEL
                     AKKVKVTFLTDPRWVRIDK"
     gene            5974..6552
                     /locus_tag="IXR40_002483"
     CDS             5974..6552
                     /locus_tag="IXR40_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362284.1"
                     /translation="MISILCIVAYHANLRLNYNADGIIVHGSLTANQIFLNYIGIWGQ
                     LGVNCFIFISAYFLSEKRNIHFENVLGIVLECIFYSVLVYGILCACGIETFSLNSFVK
                     EILSFALGRYWFITSYLALYILSPYLNIMLNNLEKLQLQKISMLLFIGVCCYRMLFKT
                     SLFGDCAVLIALYVICYTLKKTIIIFLRDTES"
     gene            6498..7016
                     /locus_tag="IXR40_002484"
     CDS             6498..7016
                     /locus_tag="IXR40_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362285.1"
                     /translation="MLYTEKNDNNIFERHRIIGTIVCITVIPLLISIGILFKFIPNAM
                     VNQMVHIGSPLMVIASIFLFYVFKNFSFYSKYINKLARTSLGVYILHENHYFIDGMKS
                     RGLIWDGIFGLGKRFLDRDFWIWFIIAVVVVCIICMAIDVVREKFERQIFKIKSVKNL
                     CKLMNHVINIYP"
     gene            7024..8064
                     /locus_tag="IXR40_002485"
     CDS             7024..8064
                     /locus_tag="IXR40_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HAQ4362286.1"
                     /translation="MRRKEVKVISFGELLLRLAAPGYSKLFQRDSLETTFCGGEANVA
                     VSLAIFGYQSEFITKLPDSDVGYAAANALRYFGVNVDNIIFGEGRMGLYYLEKGAAQR
                     PSKVIYDRKFSAISLADSDEFKWKEILNDANWFHWTGINPALSENLFETSLDACQAAK
                     KRGITISCDLNYRSKLWTSEEAKEKMEQILPLVDICICNEEDAEKVLGIKAEHTNINS
                     GELNKDGYVQVAREIHKKFGCRYVATTLRRSYSASRNGWSAMLYEAEKDKAYFSTEYN
                     IQIVDRVGGGDSFSAGIIYALCENMSGQKAIEFATASSCLKHTIEGDFNRTTIEDVYN
                     LMNSGGNGRVLR"
     gene            8313..>8473
                     /locus_tag="IXR40_002486"
     CDS             8313..>8473
                     /locus_tag="IXR40_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAQ4362287.1"
                     /translation="MTYTYLTTDELVIIESYLKINQSVAKTAHCLNRSSQTIHKVYLF
                     FKQRKSALE"
BASE COUNT         3072 a          948 c         1590 g         2863 t
ORIGIN      
        1 atttaaggca gaaggaattg attttatttt ttggtcaggt gttatttcat atatgagtgg
       61 ttcagttttt tatttaattg tatcttatgg tttaaatggt ttaatttctt atataaaaag
      121 tcttataaca ggtgaaacaa atactgcaaa ttttgctatg gaggtacatg atttaacttt
      181 tgcgatgggg gtttttttcc tttattacgt attttttgaa aataaaaata caaaaaaaca
      241 taagataaaa attatcgtat ctttaatttt aattttcatg ggattgaaga gaattgaact
      301 gttagcttta agtggtgcaa ttctagtgta ttatgtttta ttaaagtggg gaaaaaagat
      361 tcaaatccgt gcattagtgt gtactatttg tgcaactgtt atttcgttag tgtttattta
      421 cattatagat acaggaattt tggcattgct tatgtcaaat ttgggcatta cagatgacgg
      481 tgcaaggctt tcattttatc tatattcatc taaattttat gaacttggtt taggatatgt
      541 aggaacagga tggacatggt tttcaaaata cttttttaat ctttatttat cgcactttag
      601 gttaaatggt ggaagaattg cagcaagcct acacagtgat atattaacta tttatataga
      661 agttggatgt atagttttta ttatatggat gttttggtta ttttttgtga aaccgataag
      721 actaactaaa aaatttggat tgaaaacagg ggagtgtgta ttattattaa ctatatatat
      781 gtttatatta tatttgacgg ataatacgct cacttatcca gacactcaaa tgatttttct
      841 cttagtacct atgatagttt cgtgggttga taatcaacaa cgaatatcgg aatagatagc
      901 taaagtatat tttaattatg aatttataat tagttgtaaa agttaatatt taacggacag
      961 gaagtagggt gaaaaaattt gaaaaaaatt ttagtgttag caaatacata ttatcaaata
     1021 atagtagcaa tacaaatgaa aaatacaatt ttttccgatg agtatgttga aattattatt
     1081 tctgatcatt ctaaaaacac taaagaaatt gcgaaaaaaa tagaagaaaa aaaagtgttt
     1141 gatggctgtc attatttaga aagcaaatct tttgatgata atattgggta ttttcaaaag
     1201 attaaggact gtcttcagat ttcttgtggt aaatcaaatc gatatgccta ttatttgaaa
     1261 aactgtaaaa gtgaatattt tgatgaattt atttgttttt caatgggaga ggtttggttg
     1321 gaaggaatat atgcttgctt atatcgaaat aataaaaatg tacaggtatc aattttagaa
     1381 gaaggtattt taagctatgg agttgacatt attccaacag caagaacaaa agctatcgca
     1441 gtactcaatt acttaaaaaa aaggactcca ctatataaca aaagctataa tttttattgt
     1501 ttttttccta atatatatac aggaagagag aatacaatac aaattccatt agttacagct
     1561 gggtcaagaa ccgcattgca actttcggat atttttaacc ctatgataga tatttataaa
     1621 gaaaaaaaat atatattttt tacgtctgtt tatgattttg agggcggaga acctgtcgga
     1681 gaatatgaat tagtatgcaa aatagcagac ttagtaggaa aagataatct aattgttaag
     1741 acgcatccta gagatgtaag aacaatttat aaagataatg gatttatcga ggataaaaat
     1801 tcatcaatac cttgggaggc gattcaattg tcaggcgatt ttaacgataa aatatttatg
     1861 acaattaatt caggaagtgt tatttcaggt agtacaatgt ctgcaaaacc tgtacgcacg
     1921 tattatatgt ataaattgtg taacatagaa ggaaatccgt cttgcaaaaa gaatgcgtat
     1981 gatattgagc gattgcttaa gcaaaaaacg atgaaaaaca ttttaaagaa tgtgaaaata
     2041 gcagaaagct tagatgatat actatgagca aaactaaata tttaattaaa aatatgggaa
     2101 tattaacaat aagtaatttt tcttcaaaaa ttttagtttt tttgttagtc cctttatata
     2161 caagtgtatt atccacaaca gaatatggca catatgattt gacaatttca acagccacat
     2221 tattgtttcc aattttaacc ttaaacattg tagatgctgt gatgcgcttt ttaatggata
     2281 aagataaaaa taaaaaaaat atagcatcta tagcgattaa agttatattt ttaagcgtga
     2341 tagtctttgg atccgtaatg tatttgttaa atattacaaa attatggcaa gatgtttatg
     2401 gattagaaaa atatattttt ttgtattata tatcctatgt atggaatcaa tttctaatac
     2461 aatttgctaa agggttagaa aaagttaaag ctatgggcat agcaggtatt atcagcacaa
     2521 ttgtaacaat aattgccaat attttcttct tgcttattct gaaatgggga ttaattggtt
     2581 ttttcattgc aaatatttta tcacagatta tttcagctac ttatctgtca gtattagtga
     2641 gaatatggga atatatcgat tttgaggcta aagatcctca gctaaagaga gaaatgctaa
     2701 attactcgat tccattaatt gcaactgttg ttggatggtg gattaatagt acagctgata
     2761 ggtatgtggt ttcctttata gtaggtgtct cggcgaatgg cttattgtct gtggcatata
     2821 aaatacctca aataattaat actttgcagg gaatatttat acaggcctgg caaatttctg
     2881 caattaaaga atatggagat aatgagactg caaaatttta tggaaataca tttgttatga
     2941 ttaatttgtt aatgtgcata acctgttcaa gtcttatcat attaactaga ccgttttcac
     3001 atattcttta tgcgaaagac ttttatgaag cgtggaaata tgttccattt ttattaatag
     3061 ctaatgtttt aaattgtgca tcaggtctgt taggacctat cttatcagca aaaaaagatt
     3121 ctaaatccat gatgtggtct gcaatcatag gggcattagt taatgtgatt atgagtgtag
     3181 tccttgttta taagataggg gttcaaggtg ccacaatagc cactgttata tgttcatatg
     3241 taatatatgt tgttcgtaaa cgagctgtgg gaaaagatat ttttataaag cattatcata
     3301 ttgttgtgga atcttgggga ttattgtttg ttcaggcaat catagaaata tattttaaaa
     3361 attatgtaat agaaattata attatgatta ttttaattat tataaatatc agttatatta
     3421 agcagttgtg ttatagagga agaaacatta tttcaatgat taagagtcga gagcacaaac
     3481 ggtagacgat gttattttta taaaaagata taatttatta atggtcgata attatgaaag
     3541 gaaaaatatt cttaaaaaaa agagtatagg atgtcgtatg aaaatagtcg ctatagtacc
     3601 aatgaagtta aataacaaaa gattgccaca aaaaaacacg aaagctttta ccaatggaaa
     3661 accattgtgt tattatatac tttcaacact tttaaaagta aaacagattg ataaagtgta
     3721 tgtctattgt agtaacccag atattaaaga atttatacca gaaggtgtaa catttttaaa
     3781 gagatctagt tccttagatc aggatacaac gagtattaca caggtattag ccggtttcac
     3841 aaaagaagta gaggctgatg tatatgtaat gacacacaca acagcaccat ttattagcga
     3901 aaaatctatt gaaaaaggac tagatgccgt gctgacagga gaatatgatt ctgcatttgc
     3961 tgcaaaaaaa ttgcaagatt tcttatggaa agacggtgaa ccatttaatt atgaattgga
     4021 caatattcct agaacacagg atttgccgcc tttatacgaa gaaactagtg gattttatat
     4081 ttataatcgc aatgtgatga ccgagttgca tagaagaatt gggaaaaaac cttgcatagt
     4141 tgaagtaggt gagattgagt cagttgatat tgatgaagcc gaggatttta tgattgctga
     4201 tgcgatttat aatcatctta ttttacaagg tagttaagac agggggaagg ttaggatgaa
     4261 caatgtacag attttagatt gcacacttag agatgggggc tattgtaaca attgggaatt
     4321 tggatttgat aatacaaaaa aaattatttc tggacttata gaatcaggaa ttgagattat
     4381 agaatgtggg tttctcacaa ataaaacagt atacaataaa aatgttacaa aatatacgac
     4441 cttagaagaa ttagcacaga taattcctga aaaaagagaa ggaaaattat ttgtagcaat
     4501 gatgaactat ggcgaatata atatagagga tcttccagat tatgatggtt catctattga
     4561 tggaattagg attgcgtttc ataaaaaaaa ttgcaatgaa gcgttgaaat tatgtcgtga
     4621 gataaagaaa aaaggctact tagtttttgt tcaagctatg gtatctctca attatacaga
     4681 tgaagagttt ttagcagtaa taaaaaatgt gaatcagttt aaaccatacg ctttttatat
     4741 tgttgatagt tttggaatga tgaaaggaaa agatttaact cgtctttttt acatgattga
     4801 gcataatcta gaaaaagata tacagatagg ttttcactca cataataaca tgcagcttgc
     4861 atattctaat gcacaaaaac ttataaccgt acaaacaaat cgaagcctga ttattgattc
     4921 ttcggtgtac ggaatgggaa gaggagcagg taatcttaac acagaactat ttgtagaata
     4981 tttgaatgat aatgcaggaa aaaaatatca attaaaacca ttattatata taattgatga
     5041 aatactaaat agtttctatc agaagagtta ttggggatat tcattaccaa actatatttc
     5101 agcagttcat aatgctcatc ctaattatgc aagctatctg tcatataaga atactttaac
     5161 aattgaagca atgaatgaaa tattcgaaat gatggatgaa gaaaaaaagg tatcttatga
     5221 taaacaatat atagaagatt tatactacaa atatatggaa actgggaaaa tacaggagga
     5281 atatatggaa gaactgagaa aatttctctc agacaaaaaa attctactga ttgcaccagg
     5341 aaaaagttct gtagatgagg tagaaagaat aaaagagttt gttaccaaag aagaagtcgt
     5401 aataattagt gtaaattttg aatattctca tatagatata gattacgtat ttttaagtaa
     5461 tttaagacgt tttcatgaat taccgaaaga aagcagaact aaatgtattg ttacatcaaa
     5521 tatacaagca tcggatgtat atttacggac gagttataaa aagttgttat ctgaaaggga
     5581 agttgtaaga gacaatgcag gattaatggc aattagattt ttagccgata tgaatgtgga
     5641 tgaaatattc ttagctggat ttgatggata ttcacataat gaagatgaga attatggtga
     5701 gcaatccatg gaaattataa caaaatttgc attattagat gcaatgaacg tgcaaatgag
     5761 agatgaattg tcagaattag ctaaaaaagt aaaggtgaca tttttaacgg atccacgttg
     5821 ggttcgaatt gataagtagt agtaataatg tttttaaaat tttgataaag agatagtgag
     5881 agaataaaaa tgggtaaagt cttaaataaa aaagaagaaa aatatttaag ggccgatggg
     5941 gcgagatgaa actctaattt tgaactttta agaatcattt ctatattgtg tattgttgct
     6001 taccatgcta atttgcgttt aaattataat gcagacggaa ttatagtaca tggttcatta
     6061 actgctaacc agattttctt gaattatatt ggtatttggg gtcagctagg agttaattgt
     6121 tttatattta tttcggcata ttttttaagt gagaaaagaa acattcactt tgaaaatgtt
     6181 ttgggaattg tattagaatg tattttttat agtgtattag tttatggaat tctttgtgca
     6241 tgtggaatag aaacattttc attgaacagc tttgtaaaag aaatattatc atttgctcta
     6301 ggtagatatt ggtttattac atcctattta gcattgtata ttctaagtcc gtatttaaat
     6361 atcatgctta acaatctgga aaaacttcag ttgcaaaaaa taagtatgtt attgtttata
     6421 ggtgtatgct gttatcgtat gttatttaaa acatctttgt ttggggattg tgctgtttta
     6481 attgcactat atgtcatatg ttatacactg aaaaaaacga taataatatt tttgagagac
     6541 acagaatcat aggaacaatt gtatgtataa cagttatacc acttctcata tccataggaa
     6601 tacttttcaa atttatacca aatgcaatgg ttaaccagat ggttcatatt ggttctccat
     6661 tgatggttat agcaagtata tttttatttt atgtatttaa aaatttttca ttttacagta
     6721 agtatataaa taaacttgcg agaaccagtt taggggtata tattttacat gaaaatcatt
     6781 atttcattga tggtatgaag tctagaggct taatatggga tgggatattt ggattaggca
     6841 aaaggttttt agatagggat ttttggattt ggtttataat tgcagttgta gttgtgtgca
     6901 taatttgcat ggctatcgat gttgtaagag aaaaatttga aagacagatt tttaaaatta
     6961 agagtgtaaa gaacctgtgt aaacttatga atcatgttat aaatatatac ccataattaa
     7021 taaatgagga gaaaagaagt gaaagttata tcattcggag aattattatt gagacttgca
     7081 gcacccggtt attcaaagtt atttcaaaga gatagtttgg agactacatt ctgcggaggg
     7141 gaagctaatg tagcggtatc cttagcaata tttggatatc aatcagaatt tataacaaag
     7201 cttccggatt cagatgttgg atatgcggca gctaatgctt tgcgttattt tggagtaaat
     7261 gttgataata ttatatttgg agagggacgc atgggactgt attatttaga aaaaggagca
     7321 gctcagagac catctaaagt aatttatgac agaaaatttt ctgcaatttc gttagctgat
     7381 agtgatgaat ttaagtggaa ggagatccta aacgatgcaa attggtttca ttggacaggg
     7441 ataaatccag cattgtctga gaatctcttt gagacgtcct tagatgcatg tcaggctgcc
     7501 aaaaaaagag gtataacaat ttcttgtgat ttaaattatc gatccaagct ttggacatca
     7561 gaggaagcaa aagaaaagat ggaacagata ctaccattgg ttgatatttg tatttgtaat
     7621 gaagaagatg cagaaaaagt gctaggaatt aaagctgagc atacaaatat taatagtgga
     7681 gaattaaata aagatggcta tgtgcaggtg gctagggaga ttcacaagaa gtttggatgt
     7741 aggtatgtag ctacaactct gcgtagaagt tattcggcaa gtagaaatgg ttggagtgca
     7801 atgttatacg aagcagaaaa agataaagcg tatttttcca cagaatacaa catacaaatt
     7861 gttgatcgcg ttggtggtgg agacagcttt tctgctggta taatatatgc gttatgtgaa
     7921 aatatgtccg gacaaaaggc tattgaattt gcgactgcat ctagttgttt aaaacatact
     7981 atagaaggtg attttaatcg aactacaatt gaggatgtat ataatttaat gaatagcggt
     8041 ggaaatggtc gcgtgttgcg ttagtcaaca tataaagata aatcacagta atttttatgg
     8101 tgattatctg tcttagtagt gattagaata acgtgaaaat aaattgttga gcgtttatac
     8161 tgttttgaaa aataaattta acatattgaa aaatacaaat atatacgtat attataaagc
     8221 gccgattgta aaattaagct agacaactaa aacagtcatt tgtgctacac tcaaaatagt
     8281 tccgaccaaa gaattataag gagtgagtgc aaataaccta tacctatctt acaacggatg
     8341 aacttgtaat aatagagtct tatttgaaaa ttaaccaatc tgttgctaaa actgcgcatt
     8401 gcttgaatcg ttcaagtcaa acgatccata aagtatatct gttcttcaag caaagaaaat
     8461 cagccttaga ata
//
LOCUS       DACGEU010000108         8187 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.111, whole genome shotgun sequence.
ACCESSION   DACGEU010000108 DACGEU010000000
VERSION     DACGEU010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8187)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8187)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8187
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.111"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(1..859)
                     /locus_tag="IXR40_002487"
                     /pseudo
     CDS             complement(1..859)
                     /locus_tag="IXR40_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            1102..1557
                     /gene="tnpA"
                     /locus_tag="IXR40_002488"
     CDS             1102..1557
                     /gene="tnpA"
                     /locus_tag="IXR40_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HAQ4362288.1"
                     /translation="MSNDDKSLAYTRWNCKYHIIFTPKYQRKVIYGQLRKDLGKILRK
                     LCEMKDVEIIEAHAMLDHIHMLVRVPPKICISSFMGYLKGRSAVLIHEQHANLKYKYG
                     NKSFWSKRYYVSTVGLNQKTNEKYIREQEADDRIRYIISKREYVEPFKK"
     gene            1822..1920
                     /locus_tag="IXR40_002489"
                     /pseudo
     CDS             1822..1920
                     /locus_tag="IXR40_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(2143..2373)
                     /locus_tag="IXR40_002490"
     CDS             complement(2143..2373)
                     /locus_tag="IXR40_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="resolvase"
                     /protein_id="HAQ4362289.1"
                     /translation="MDEAMDHPLLNKFIKDLILQIFSMIDEQEPTESKRHRAQGIIKI
                     AKRMFSIKGVLSYTVLIQKIPNHLVYKNNVED"
     gene            complement(2603..3421)
                     /locus_tag="IXR40_002491"
     CDS             complement(2603..3421)
                     /locus_tag="IXR40_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAQ4362290.1"
                     /translation="MSYIYLIKENYPFLTKSEKKVADFILNSGKTIIYSTMSDIKKNT
                     KVGDATIIRFCQKIGFSGFSDLKIEIAKEDFSQKKEHPTSVKYYDEIANSLTEALYST
                     IRLLDEEKLNEAIKMITQSKNIYIFGVGSSGNTSLDLENMFLRVGVQAKAVLDPHFQA
                     QVASLLTVNDLVIIFSLSGKTKDTYDSLKIAKKNGAKIIAITNYIHSPIGKSADLVLQ
                     TAIEEFLNGGSLAGKISQLYICDLLVHGYEQNNNIDSVELREKVLRSIIDKSIE"
     gene            3582..4271
                     /locus_tag="IXR40_002492"
     CDS             3582..4271
                     /locus_tag="IXR40_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HAQ4362291.1"
                     /translation="MDKKRFLDLISKGLIVSCQALPGEPFYKEEESLMPYFALAAQRA
                     GAVGIRANSVRDIIEIRKCVSLPMIGIIKRDYPPESPFITATMREVDELVETGVEVIA
                     LDCTLRNRHDGLSINSFITKIKEKYPHQLFMADISTFEEGKNAYKAGIDFVGTTLSGY
                     TEESKKQDGPDIDLIKKLVEEGICVIAEGRIHTPEQAKEIKKIGVAGIVVGGAITRPQ
                     EIASRFVKALS"
     gene            4285..5787
                     /locus_tag="IXR40_002493"
     CDS             4285..5787
                     /locus_tag="IXR40_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010759843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4362292.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPFL
                     DQPWLHTILSIMSYAGNAVFANLALIFAIGIAVGLANGDKGTAGLAGGVAYLVYTATI
                     SGFLELFSAKDATLDTGVVGSIVVGGTVAFLHNRYRKIELPQFLGFFGGSRFIPIVSS
                     LAAIIIGSFFYLIWPPIQNGLVVAGEQIAQMGSLGTFLYGFLLRLTGAVGLHHTIYPL
                     FWYTSLGGTETVAGSTIAGAQNIFFAQLADPNHTGLFTYGTRFFAGRFATMMFGLPAA
                     CYAMYRAIPKKNRKKNGGLYFSGALTSFLTGITEPVEYMFLFVAPWLYVIHAFLDGLS
                     FYFADILNIRVGNSFSGGLIDFLLFGVLQGNDKTNWLKLIPFGIAWAFIYFFVFTFFI
                     KKFKVAIPGMEEEVEVHSEKVINKNTSLHEESLIIIEALGGKENIESVEACATRLRVA
                     VTNGEIIQKQTIKDTGATAVFEVKGGIQAVFGGKADLLSQEINQILGKDN"
     gene            5800..6276
                     /locus_tag="IXR40_002494"
     CDS             5800..6276
                     /locus_tag="IXR40_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HAQ4362293.1"
                     /translation="MFEIFKKKKQETFYAPCSGKIISITEVNDPVFSQKLLGDGFAVI
                     PDGSKIYAPLAGRVTNIFPTKHAINIKSNSGIDYLIHIGIDTVELQGEPFSICVQEND
                     DVTPETSLVDVDFDKIIKSGKDTSVIVVFPEKNQFNDLIIDNGRIAHGNSCGKITF"
     gene            6595..6828
                     /locus_tag="IXR40_002495"
                     /pseudo
     CDS             6595..6828
                     /locus_tag="IXR40_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303482.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(6987..7109)
                     /locus_tag="IXR40_002496"
     CDS             complement(6987..7109)
                     /locus_tag="IXR40_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002389461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HAQ4362294.1"
                     /translation="MKGVSLLSAYETIQTILGFGMFTIALISLIVNMLKNDKKK"
     gene            7264..7524
                     /locus_tag="IXR40_002497"
     CDS             7264..7524
                     /locus_tag="IXR40_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362295.1"
                     /translation="MEYYTGLLDKIRVIKTQPLLVRFTLHTSHEPINCVVANIEIADK
                     LLILEEGKYTISVTGHFNKRNQLVIESMQIRNPDHFTQSMGI"
     gene            7968..8174
                     /locus_tag="IXR40_002498"
     CDS             7968..8174
                     /locus_tag="IXR40_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HAQ4362296.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPYTVECDCGERAKCIKSYCLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
BASE COUNT         2668 a         1333 c         1502 g         2684 t
ORIGIN      
        1 acttgtcctc gataagaatt gtagcgccgt gatttacgtg tgtatgtcgt tacttttatt
       61 cctagcttct tgatcaggcg ctgaactttc tttttattga tagagaaacc gcggtttctt
      121 agttcattgg tcatccgtaa acagccataa tccttgtgct tctcccgaac tttaagcatt
      181 tccgcttcaa tctcttgatc tggattttta cggtccaatc gtttttgcca gtacataaag
      241 attgccttag ggaactttaa agtttctaga agctcaacta atttaaacgg tcctcggagg
      301 cttgcgatga ttcgtgcgat tgcttcattc gtcgttgttg ggcttcctgt tttcgcagct
      361 tcctcaattc ttttaaaaag gcattttcaa tttgaaggga acggactcgt ttctccaact
      421 cctcgatgcg ttcacgttct ttagacgttg ctttagttgt agattttttc ttatttttgg
      481 gttcattttt cttagacaag ataggtggac atcctttcgt ttttgagagt ccatcgatcc
      541 caccctcacg gaattgacgc atccaactag cgatcaaatt agggttgttc atgttaagtg
      601 tgttggcaac ttcacgatag gacagctcac ttgttagata taactctatc gcatccagct
      661 taaattgaac agaatatttt ttcttttgtc gctttcttac tagaccctct tcaccaaatt
      721 cttgataggc attgatccag cgcttcactt gtgatggagc cttaatggaa tatttctttg
      781 ccagataatc acttccgcct ttaccatcca agtaatcatg aacgatcttt aatttaagtt
      841 caaaagtata cttagccata aaaaataccg acctccaaaa gttagatttt ttggtctaac
      901 ttttgggggt cggtacaaaa cttaaaagtt ttagaccctt ttattttctt aatgacttca
      961 gtcagttttg tgcgtaaagc gtgcgaaaca agaaaaccgc gcgtttctac gcgtggaaga
     1021 agtatcttta gcgataaaaa ctcctttcga tatactagtg agtggctacc aaccgctcat
     1081 cagatcgaaa ggagtttttt catgtcaaat gacgataaaa gtttagcata tactcgttgg
     1141 aattgtaagt atcatattat ttttacacca aaatatcaac gaaaagtaat ctatgggcaa
     1201 ttacgaaaag atcttggaaa aatacttagg aagttgtgcg aaatgaaaga tgtggaaatc
     1261 atagaagcac atgcaatgct agatcatatt cacatgcttg ttcgagtacc accaaaaata
     1321 tgtatatcca gttttatggg gtatctgaaa ggtcgtagtg cggtactaat ccacgagcag
     1381 cacgcaaatc tcaaatataa atacggaaac aaatcctttt ggtcgaagag atactatgtg
     1441 agtacagtcg gattgaatca aaagacaaat gaaaaataca tccgtgaaca agaagctgat
     1501 gatcgcattc gatatattat aagtaaaaga gagtacgtag aaccatttaa aaaataaaga
     1561 gaagtaagtg agtgaagatg agcagttggc ggtcttttaa aaatcccctt ttaaggggca
     1621 gcgagtgtcg accccttcta gggggattaa aaatacaccc gtcctcacgg gtgtatgggt
     1681 tactgataga cttgatttta actggtgtca gaaacttatg tccagaaagg gtgatgaaat
     1741 tttggcaatt tacggctatt caagaattag cacaagcaac caagattaca aaacacaaat
     1801 tcaaacatta gaaaatgctg gcgcagaaat aatcttccta gaaaatcact ggattatcga
     1861 acacctttgg aagtattttt gagttacgta agtattgatg atctgtctaa cttaatttga
     1921 caattaagag tatatttact tcagatggta aggcaacaaa ataaaataca ataggcagat
     1981 gaactaataa ataaaatctg tattaaatac agataaatta atataaaaat caaaaggatc
     2041 ataaactttt aacaagtgat gaaatgggtg gaaattgatt cttatagaca gtttgtctca
     2101 taacattgaa gtattttgca attttagcat tgaaacactt ttttaatctt caacgttgtt
     2161 cttataaaca agatgattgg gaatcttttg aattaacact gtatagctta gaacaccctt
     2221 tatagaaaac attcgcttag caatcttaat aattccttgt gcccgatgtc gtttagattc
     2281 agtaggttcc tgctcatcga tcatggaaaa aatttgaagg atcagatcct taataaattt
     2341 atttaagaga ggatgatcca ttgcttcatc catactcgat aaactagtga taatgagcta
     2401 cacgtttttc tttcaagttg atcaatagct tccacgataa aaatatcttt agataaaatc
     2461 aagaaccgta ggaactacag ggatatttgg tcaataagag ccaccgctat tagtaaaaaa
     2521 taagctatca agtatgctct catcccaaga attgcctact tcaatcgtta aaaaccgtta
     2581 ggtttagcta agtgggggta gttcactcaa tacttttatc aataatagag cgcaaaactt
     2641 tttctcttaa ttcaactgaa tcaatattat tgttttgttc ataaccatga actaatagat
     2701 cacaaatata aagttgtgat atttttccag ctaaagatcc accattaaga aattcttcaa
     2761 tggctgtttg taaaactaag tctgcagact ttcctatagg tgaatgaata tagttagtta
     2821 tagcaataat ttttgcgcca ttttttttag ctattttcaa tgaatcataa gtatctttcg
     2881 ttttcccaga taaagaaaaa atgattacta aatcattaac tgttaataaa gaagcgactt
     2941 gggcttgaaa atgagggtct agtacagctt ttgcttgaac tcctacgcga agaaacatat
     3001 tttctaaatc aagactagta tttccactag atcccactcc aaatatatat atgttttttg
     3061 attgagtgat cattttaatg gcttcattca atttttcttc gtctaaaagc ctaatagtgg
     3121 aatagagagc ttctgttaaa ctattagcaa tttcatcata gtactttaca ctagtcggat
     3181 gttctttttt ttgactaaag tcttcctttg caatttcaat ttttaaatca gaaaaaccag
     3241 aaaaaccaat tttttgacaa aagcgaataa tagtagcatc gccaactttt gtgtttttct
     3301 taatatcact catcgtacta taaataatag ttttcccaga atttaaaata aaatcagcga
     3361 cttttttttc agacttcgtt aaaaatggat aattttcttt aattaaatag atataactca
     3421 tacaaactcc tctacaattt caacttttct ccattatact ccaaaataat aaaaaaaact
     3481 cctaaatact ccatttttat ctttactttt atgaaagcgg atgctatatt gtttttggag
     3541 ttgttatcca aaaataataa aaaattggag tgtttaggat aatggataaa aagaggtttt
     3601 tagatcttat ttcaaaaggt ttgattgttt cctgtcaagc attacctggt gaaccatttt
     3661 acaaagagga agaaagttta atgccttatt ttgctttggc tgctcaaagg gctggagcag
     3721 ttggtatacg tgcaaattct gttcgagata ttattgaaat tagaaagtgt gtatcattac
     3781 caatgattgg aattattaaa agagattatc caccagaatc tccattcatt actgccacta
     3841 tgagagaagt agatgaatta gtagaaaccg gtgttgaggt aatcgctctt gattgcactc
     3901 ttagaaatcg acatgatgga ctatctataa attcttttat tactaaaata aaagaaaaat
     3961 atcctcatca gttatttatg gcagatattt ctacatttga agaaggcaaa aatgcatata
     4021 aagcaggaat agattttgta ggaactactt taagtggata tactgaggaa agtaaaaaac
     4081 aagatgggcc agatatagat ttgattaaaa aattggtaga agaagggatt tgtgtaattg
     4141 ctgagggaag gattcatact ccagaacaag caaaagagat aaaaaaaata ggagttgcag
     4201 gtattgttgt gggtggtgct attactcgac cacaggaaat tgcatcaaga tttgttaaag
     4261 cattaagtta gggggagaaa taaaatgttt aaaaaatttt cacaattagg acgcgctttc
     4321 atgttaccaa ttgctatatt accagtagcc ggattactat tgggactggg aggagcgtta
     4381 acaaatgaga gtgctataaa tgcttatcca tttttagatc aaccgtggtt gcatacaatt
     4441 ttaagtatta tgagttatgc tggaaatgca gtttttgcaa acctagcact aatttttgca
     4501 attggtattg ctgtaggact tgcaaatgga gataaaggaa cagctggttt agctggtgga
     4561 gtagcttatc tagtatatac tgcaactatt agtgggtttc ttgaactttt ttcagcaaaa
     4621 gatgcaacac tagatacagg tgtagtggga tcaattgttg ttggtggtac tgttgcattt
     4681 ttacacaatc gttatagaaa aattgaatta ccacaattct taggtttttt tggaggatca
     4741 agatttattc cgattgtttc tagtttagct gcaatcatta ttggttcttt cttttattta
     4801 atttggccac caattcaaaa tggtttagta gttgctggtg aacaaattgc ccaaatgggt
     4861 agtttaggaa cttttttata tggtttttta ttgcgtttaa caggtgctgt tggactacac
     4921 cacaccattt accctttgtt ctggtataca tctttaggtg gtaccgaaac tgtagctgga
     4981 tcaacaattg ctggagccca aaatattttc tttgcccaac tagctgatcc aaaccacact
     5041 ggtctgttta cttatggtac tagatttttt gcaggaagat ttgcaacaat gatgtttgga
     5101 ttaccagcag catgttatgc aatgtatcgt gcaattccta agaaaaatcg taaaaagaat
     5161 ggtgggcttt attttagcgg ggcccttaca tcatttttaa ctggaattac tgaaccagtt
     5221 gaatatatgt ttttatttgt tgctccttgg ctttatgtga ttcatgcatt cttagatgga
     5281 ttatcttttt attttgctga tatcttaaat attcgtgtag ggaattcctt ttcaggtggt
     5341 ttgatcgact ttttattatt cggtgtactt caagggaatg acaaaactaa ttggttaaaa
     5401 ttaattcctt ttggtattgc atgggcattt atatatttct ttgtttttac attctttatc
     5461 aaaaaattta aggtagctat tcctggaatg gaagaagaag tagaagttca ttctgaaaaa
     5521 gtaataaaca aaaatacatc attacatgaa gagtctctta tcattattga agctcttggt
     5581 ggaaaagaaa atattgagtc tgttgaagct tgtgcaactc gtttgcgtgt tgctgttacg
     5641 aatggggaga ttattcaaaa acaaacaata aaagacactg gtgcaactgc tgtcttcgaa
     5701 gtgaagggtg gtatccaagc tgtttttgga gggaaagctg acttactaag tcaagaaatc
     5761 aatcaaatat taggaaaaga taattaggag gtttttaata tgtttgaaat tttcaaaaag
     5821 aaaaaacaag aaacttttta tgcaccttgt tccggaaaaa tcatttccat cacagaagta
     5881 aatgatcctg tcttttcaca aaaattacta ggtgatggtt ttgccgtcat acctgatggt
     5941 tcaaaaattt atgctccatt ggctggtcga gtaacaaata tatttcctac taaacatgct
     6001 attaatataa aaagcaactc aggcattgat tatttgattc atattggaat tgatacagtc
     6061 gaattacaag gagagccttt ttcgatttgt gttcaagaaa atgatgatgt tactcctgaa
     6121 acctcgttgg ttgatgtgga ttttgacaaa ataataaaat ctggtaaaga tacttctgtt
     6181 atagttgttt ttccggagaa aaaccagttc aatgatttaa taatagataa tggtcgaatt
     6241 gctcatggga attcatgtgg aaaaatcact ttttaaaaaa gtgtatataa aaagctataa
     6301 aataagctaa ataggatatt tgtaaaatga agttgctgaa cagaaagaac tgttttcttt
     6361 ctgttcattt ttttatttta acgtaattca ggcagaagtc gcccatcctc tataggtggg
     6421 tgaggaatgc agttcggtat gagggttacc gttggtaact cgaaaaccga caattaagac
     6481 atatttcctt tttattttgt tccatgtttc aatcagtcta tataagaaat gggttgatat
     6541 aacatgacat tagatacaaa taatcattca gtatttcttc tttattacca ccttatttta
     6601 gtaacaaaat atcgtagaca agtaatagac gggatttctt tgggcgtcac tgaaaatcct
     6661 ttggtaaata gaattgcgaa aggatcacta tttcttgtat tcgtgtatct tgtctgttct
     6721 tatcttttaa aaagagcagg aaaggataat tccttttggt gattgactaa agtcacaata
     6781 gccgcgacag ctgttatact tacggctatt ctaccgcttt atatgtaggg ttaacgggaa
     6841 atcattgaac ttcttgcgaa atattgctat aatgaacgtg aaaaagagga gttgcacgaa
     6901 caacccctca gtaacagcac cgattaaaga acggtggcag aataatagtt atttggaaat
     6961 aaccgctgac ctgctaaagt agacggttat ttctttttgt catttttaag catatttaca
     7021 atcaaactaa tcaaagcaat ggtaaacata ccaaaaccaa gaatggtttg aattgtctca
     7081 tatgcggaca aaaggcttac tcctttcata gattttagca cttacattca taagcaccac
     7141 cacctttcca gaagtcgcca ccgtcttcaa actttactgt cttgattatt atagcatatc
     7201 taaaatcgaa taaaaattct caattttagc tggttttgct ataattttat cgaggtgatc
     7261 gcgatggaat attatactgg tttactcgat aaaattcggg tgatcaagac acagccattg
     7321 cttgtgcgat ttacattaca cacgagtcat gaaccaatca attgtgtagt ggccaatata
     7381 gaaatagcgg ataaattgct gattttggaa gaaggcaagt atactatttc agtgacaggt
     7441 cacttcaata aacggaatca attagtcatt gaatcgatgc aaattagaaa ccccgatcat
     7501 tttacgcaat cgatgggcat ataaaagaag agctgcagtc ctaaatgagg attgtagctc
     7561 tttttgtttt acatagaaac agtaaaaatg aaaaggcctg tttaggaagg cacaagcgcc
     7621 ttctcaattg aaaaaccttt ctctcactcc aaccgccacc gccgttcgag aagaaaggaa
     7681 gtgaacgcta cgcgttcact aagataaagg gtcttgcata gcaagacaaa atagaaaaaa
     7741 cttcctctca ccaaaaggtt cgctcctgtt cgttatctct ttattgattt gtcagaccgt
     7801 caacaagttg ccttttatca ccaaaaagcg acaaggacaa gggtaaatgg cacgctgcac
     7861 gcccttgtcc ttgtcgcttt tagttgattc attctggcca acaaatcaat aaagaaagaa
     7921 ctaacgaaag gaagtaaaac ctttcctaag aggaggcaga atcaatcatg cgaaagaaat
     7981 ttgattattg gggtgttccc ttcagcgaat tattcccaaa ctatcatgca ccatatactg
     8041 tcgaatgcga ttgtggagaa agagcgaaat gtatcaaaag ctattgtttg tatcaatgtc
     8101 caacatgcgg gaaaaaatat accttgtctt atggcgatta tattttgatt gatgagaaag
     8161 gaaagaaacg ctgatgaaaa cacaaca
//
LOCUS       DACGEU010000109         8147 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.112, whole genome shotgun sequence.
ACCESSION   DACGEU010000109 DACGEU010000000
VERSION     DACGEU010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8147)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8147)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8147
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.112"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            <1..1827
                     /locus_tag="IXR40_002499"
     CDS             <1..1827
                     /locus_tag="IXR40_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HAQ4362297.1"
                     /translation="DENIPKPTTEERIATLKKNFENVNAENVAFYQKLPNNFYSTIFE
                     MTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEDQIQYLNVTTEQQQMIRYLV
                     DQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKLELLGLT
                     NQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSIVLMKFFQ
                     LFQTEQATYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIGTNFLTI
                     ILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIVYQGMSFGDATTWLM
                     LVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEAPGTYHH
                     SMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPHNFLLPE
                     DSKHIIFGHVTDGAKILEDYNMPQMVIDICKQHHGTTLMRYFYIKAKERNPEVTEEQF
                     RYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQLDDSGL
                     TLKEIRKVEKSLISGLSSTFHSRIKYPKMKTEVEKIKEEQEE"
     gene            1844..2320
                     /gene="ybeY"
                     /locus_tag="IXR40_002500"
     CDS             1844..2320
                     /gene="ybeY"
                     /locus_tag="IXR40_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HAQ4362298.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLKLPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISIER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            2298..2699
                     /locus_tag="IXR40_002501"
     CDS             2298..2699
                     /locus_tag="IXR40_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HAQ4362299.1"
                     /translation="MPMDSKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFG
                     ILALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKD
                     MAAGAVLVTACFAVIIGLILFVPKIYHLLFN"
     gene            2714..3613
                     /locus_tag="IXR40_002502"
     CDS             2714..3613
                     /locus_tag="IXR40_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HAQ4362300.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            3756..4568
                     /gene="recO"
                     /locus_tag="IXR40_002503"
     CDS             3756..4568
                     /gene="recO"
                     /locus_tag="IXR40_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HAQ4362301.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRNIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKSGGVICEKHWPMDEHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRDLIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKTPEKNMPEKEIPEKEE"
     gene            4952..5869
                     /gene="glyQ"
                     /locus_tag="IXR40_002504"
     CDS             4952..5869
                     /gene="glyQ"
                     /locus_tag="IXR40_002504"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HAQ4362302.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPENMKEAE"
     gene            5871..7946
                     /locus_tag="IXR40_002505"
     CDS             5871..7946
                     /locus_tag="IXR40_002505"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HAQ4362303.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKEAKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEVIPFEILDVKTGRASRGHRFLGEDVTFAHAKEYEEKLNEQFVIASPQKR
                     QEMIVTQANELAEKNHWVIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGELPQSTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISD
                     VISKDTDRFGIGLSEGQQQVIDFIKGRLRQLLTTKNIRHDVIEAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAELEKQSEVDPELFENEAEKELHKAVEA
                     MKKSFADQTINENYDQLVSLRPLIENYFDQTMVMAEEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
BASE COUNT         2714 a         1464 c         1756 g         2213 t
ORIGIN      
        1 gatgaaaata tcccgaaacc tactacagaa gagcggattg ctacactgaa gaaaaatttt
       61 gaaaacgtga atgcagaaaa cgttgcgttt taccaaaaac tgccgaacaa tttttattcg
      121 acgatatttg aaatgactga aacggaaatt cacacggtta gggatgaaag tttgaagctc
      181 attgacgaac agatgagtaa acaagttcgt gaaagcgaat tggaagcttt taaacaagaa
      241 gcagaagatc agattcagta tttgaatgtc acaacagagc agcaacaaat gattcgctac
      301 ttagtggatc aaggcattgt agtcaatgat gtattgaatg agaaaaagac agaagaatta
      361 aaacaatctg cacgagaagc tgtacaacca gtgatgatct tccaaggaga aatcattgtt
      421 cgcgaaggaa atcaaattga tgcttcagcg atgaaaaaat tggaattact aggattgacg
      481 aatcaaacga cttcgatttt cccactcatt gccatggttt tagctgtttt gcttcaaatc
      541 ggcgtactga tttataattc acttcaattc caaaatgcag gagaaagaac aaaatacgtg
      601 cttttctatg tgacagctat gtcagtcagc atagtgctga tgaaattttt ccaattattc
      661 caaacggaac aagctactta tatcccgctg ttttatcccg ctgcttttgc accacttgtt
      721 ttaagctttt tcttgaaccg aagagcaggg atcatggctg gtattttcca agcagtatct
      781 gcacttttca ttttttatga ttcgattggc acgaactttc taacgattat cttgatgtct
      841 tatgttttct ctgggctcat ggcaacgatt gtcagacgca aacggatctc agaacaagga
      901 ttatctgctg ccatgtgggt cattattttt cctgtgatga tggatgtcat tttgatcgtc
      961 tatcaaggaa tgagctttgg tgatgcaacg acttggttaa tgcttgtctg cgggttcact
     1021 ggtgcactct tctcattctt gctgacgatc ggtctacacc catatattga attgatggtc
     1081 aatgatgaca gtgtaattgt attaaatgaa ctcagcaatc caaatcatcc tttattgaaa
     1141 cagttgctgg aagaagcgcc aggtacttat catcatagta tgatggtagc taatctaagt
     1201 gctaacgctg tagcagaaat cggcggacgt tctttgctaa ctcgagtagc ttgctattat
     1261 catgatatcg gcaagatcaa acatgctagc tttttcgttg agaacttgcc ttcaggagcg
     1321 gaaaacccgc acaatttctt attgccagaa gacagtaaac atattatctt tggacatgtg
     1381 acagatggag ccaaaatatt ggaagattat aatatgccgc aaatggtgat cgatatttgc
     1441 aaacagcatc atggaaccac gctaatgcgt tatttctaca tcaaagcgaa agaacgcaat
     1501 ccggaagtaa cagaagagca attccgttat cctggaccaa aaccgcaaag tcgtgaagca
     1561 gggatcgtca atattgctga cagttgtgag gctgcagtac gggcaatgga tcatccgacg
     1621 agcgaaaaaa tcgaaagttt tgtccataat cttatcgaag agcgtatttc cgatggtcaa
     1681 ttagacgata gtggactgac cttgaaagaa atccgaaaag tggaaaaatc attgatcagc
     1741 ggtttaagta gcaccttcca ttctcggatc aaatatccta aaatgaaaac agaagttgag
     1801 aagataaagg aagaacaaga agaatagaaa gaagcgatgt ataatggata ttacctttat
     1861 ggatgaaaca aaccaagtct cagaagagaa aatgaaagaa atcgatgact tgctgcaatt
     1921 tgcagcatct tatttaaagc tgccagagga aacagaaatg tctgttactt tcatggacaa
     1981 tgcggcaatc caagtaatca atcgtgatta ccgtggaaaa gatgcaccga cagacgtcat
     2041 cagttttgct ctggaagaag aaggcgaaga cgaaatccca gtgatttttg aagatggaga
     2101 gaatcctttg cctcgtgtac taggagacat catgatttct attgaacgtg ctgctgaaca
     2161 agcagaagct tacggccatt catatgatcg ggaacttggc tttttagcgg tacatggatt
     2221 cttgcatatc aacgggtatg accatatgac accagaagat gagaaagaaa tgtttggttt
     2281 acagaaagag atcttggatg cctatggact caaaagataa aaacgtagag aaaaacaaac
     2341 atttcctgat gtctgtggaa tttgctgtcc aaggagtcaa aaccgttttt gaggaagaac
     2401 gcaatatgag gaaacatgtt gcgttcggta tccttgcttt atttatgggc gtgattttcc
     2461 agcttgatcg gatagagtgg ttatggctgc ttttagctgt ttttctcgtt tggatagtag
     2521 agatcatcaa tactgttttt gaaaatgtag tggacatgtt tacggatttt cattttcatc
     2581 cgattgggaa aaaaatcaaa gatatggcag ctggagcagt tttagtgacc gcttgttttg
     2641 ctgtcatcat tgggttgatt ttatttgtcc ctaaaatata tcatttgttg tttaattaaa
     2701 aaggagaacg tatatgccag aacataaatc agggtttgtc gcaatcgtcg gccgcccgaa
     2761 tgtaggaaaa tccacattat tgaaccgaat cgtgggtcaa aaaattgcca ttatgagtga
     2821 caaggcacag acaactagaa ataaaatcca aggagtatat actacaccag aagctcagct
     2881 gatttttatc gatacaccag gaatccataa accaaagcat cgtctaggag attttatggt
     2941 agaagcagct tacagtgcgt tgaaagaagt ggatgcagtc ttatttatga tcagtgctga
     3001 tcaaaaacgc ggccggggag acgattttat tattgaacgt ctaaaaaacg tgcattctcc
     3061 agtttatctg attatcaata aaatcgataa gatccatcca gacgagttgc tgggaatcat
     3121 cgaagattat tcgacgcaga tgccttttgc acaagtgatt ccgatctctg ctacagaagg
     3181 aaacaatgtc gaacgcttaa tggatgtatt agtcagtgaa atgccagagg gcccacaata
     3241 ttttccagat gatcaagtga ctgatcatcc tgaatacttt atcgtttctg aattgatccg
     3301 tgagaaagtc ttgtttttaa cacgagacga agtgcctcat tctgtcgcag tcgttgttga
     3361 ttcgatgaag cgaaacgaga atgataaaat ccatatccag gccacgatca tcgtcgaaag
     3421 agatagccaa aaaggaatca ttatcggcaa aggcggaaaa atgctgaagc aagtaggaac
     3481 gaaagcaaga aaggatatcg aaaatctttt aggagacaaa gtatttctag aactttgggt
     3541 caaagtccaa aaagactggc gagacaaaaa agtctatctg caagactttg gctaccgaaa
     3601 agacgaatac tgatattctg aacttcttat aggttaagta tagaaataaa ctggataaaa
     3661 atccgcacgt tgagaaaaac ggcggaagat cgaaacataa ataatctgga tcggcagaat
     3721 ctgcttttcc agatttattt tttaggaggg agaatatgag ccagcttgca gaatcgaaag
     3781 gcttgatttt atctagccgt aattacaaag aaaaagataa attagtcaaa atctttacgg
     3841 aatcttctgg caaaatgatg ttttatatca aaggaatcca tcggcaaaat cagccattag
     3901 ctccggcttt gctccccttt accgaagcag tctatatcgg taattttcga agtgaaggtt
     3961 tgtcgttttt aagcagtgtc aaagacgtcc atgcgtttcg gaacatccaa gaagatatct
     4021 ttttgagcgg ttatggtacc tatttgctaa atctagtaga tgcagcaatc gaagatcatc
     4081 aatatgaccc gcatttattc caatttacgc aacaagctct gcagcggatg gatcaaggag
     4141 atgatgcaga aatcatcacg aatatctttg aagttcaaat actgcaacgc ttcggaatcg
     4201 cgccaatttg gacgcactgt gtcgtatgcg gggaaacaaa aggaaaattt gactattctt
     4261 ccaaatctgg cggtgtgata tgcgagaaac actggccaat ggacgaacac cgttatcatg
     4321 cagatcctcg cgctgtttat ttcgttcgaa tgttttcggc tatttcttat gataagatca
     4381 gtggaatcca cttgaaagaa gaaacgaagc aggcaatccg tgacctcatt gaccagttgt
     4441 atgatgaata tgtcggtatt catctaaaaa gcaaaaagtt cattgatcaa atgaagtctt
     4501 gggcacacgt attaaagacg ccagagaaaa atatgcctga aaaagagata cctgaaaaag
     4561 aagaataaat gaaagataca acaaaaaaat caaaactatt tgacaaatac agggacttcc
     4621 gtctattatt aaccgtagat taaatagatc gttcactgag aggatctatt atataaacaa
     4681 gaaaactgca aaatgaatac gtacattgac caagatcagt aaaaaacacg tggtttagcg
     4741 agttcgggag agtggaagcc ggacccaaac gatttttgaa gaggcacttg cgagtacgat
     4801 aaatgaagct gccgaatctt tattcggaag tagggtggaa ccgcgaaatt attcgtccct
     4861 atgtctgtaa tcagacatag ggactttttg tcgttttctt tcctgtattc ttattgacag
     4921 caacgcttaa aaattgaaag gggcaaaaca gatgagtaaa aaattgaccg tccaagatat
     4981 gattttaaca ttacaaaaat tttggtcatc aaacggctgc atgctgatgc aagcttatga
     5041 cacagaaaaa ggagcaggta cgatgagccc atatacattc ttacgggcaa tcggaccgga
     5101 accatggaat gctgcttatg tagagccatc ccgccgacca gctgacgggc gttatggaga
     5161 aaacccaaac cgtttgtatc agcatcatca atttcaagtc gtaatgaaac cttcacctga
     5221 aaatatccaa gagctttatt tagaaagctt gcgtctttta ggaattgatc cattagaaca
     5281 cgatattcgt tttgttgaag acaactggga gaacccatcg atggggtgtg ccggtgtggg
     5341 ttgggaagta tggcttgatg ggatggagat cacacaattc acgtacttcc agcaagtcgg
     5401 aggactacct tgtaaaccag ttacttctga gatcacttat ggactagaac gtcttgcttc
     5461 atatattcaa gaagttgaaa gtgtctatga tctggaatgg gctgatggtg tgaaatatgg
     5521 cgagatcttc aaacaaccag aatatgaaca ttccaaatat tcttttgaag taagtgacca
     5581 agacttgcta ctaagcaact ttgaccgttt tgaaaaagaa gctaaacgct gtatcgatga
     5641 aaatcttgtt catccagcgt atgattatat tttgaaatgc agccatacat tcaatttatt
     5701 agatgctcgc ggtgcagtat ccgtaacaga acgagcaggt tatctttccc gtatccgcaa
     5761 catggctcgt gctgtagcca aaatctttgt ggcagaacgc gaaaaattag gattcccttt
     5821 attgaataaa aacacagcaa atccagaaaa catgaaggag gctgaataag atggcaaaag
     5881 acttattact tgaaatcggg ctggaagaaa tgcctgctca tgttgtcaca ccaagcatga
     5941 aacaattaga agaaaaaaca gcaaaatttt tagatgaaaa ccaattgact tatgatacga
     6001 tcgaaacgtt ttctacaccg cgccgcttag caatcaaagt aacaaacatt ccagaacgtc
     6061 aagcagacag tgaagaagaa gtcaaaggac cagccaaaaa aattgctttg gacgcagatg
     6121 gaaactggac gaaagcagct gaaggatttg tccgcggaca aggtctgacg acagatgcta
     6181 tcacttttag agaattaaaa ggcgtggaat atgtctatgt aacgaaatac actcacggca
     6241 aagaagcgaa agaagtattg acaggtttag cagatgtcat taaaagcctc actttcccag
     6301 taacgatgca ttgggcagaa tacgattttg aatatatccg ccctattcac tggatcgtgg
     6361 cattgttaga tgacgaagta atcccgtttg agatcttaga tgtcaaaaca ggcagagcct
     6421 ctcgaggaca tcgtttctta ggcgaagatg tgacatttgc gcatgcaaaa gaatatgaag
     6481 aaaaattgaa tgaacaattc gttattgctt caccgcaaaa aagacaagaa atgatcgtta
     6541 cacaagcaaa tgaattagcc gaaaaaaatc actgggttat tgatctagac gaagatttac
     6601 tagaagaagt caacaattta gtcgaatatc caactgtctt ttctggcgac ttcgaagaaa
     6661 aatatctttc tgttcctgaa gaagtactag tcacttctat gaaagaacat caacgttatt
     6721 tcgaggtacg gaacgatcaa ggtatgctgc ttcctcattt tatttctgct cgtaatggtg
     6781 atcgggtaaa attggaaaat gtggttcgag gcaatcaaaa agtattgacg gctcgtttag
     6841 aagatgcgga attcttttat aatgaagaca agaaagcttc aatcgaccaa tacgttgaaa
     6901 aactaaaaac tgttactttc catgaaaaaa tcggtagtat ctatgagaaa atgcagcggg
     6961 tacaagtcat tgcccgtatc attggcgaac aagtaggact atctgaggaa gaattgatgg
     7021 atctgcaacg agctgctgaa atctataaat ttgatctagt aaccaacatg gtaggggaat
     7081 ttcctgaact acaagggatc atgggcgaaa aatatgctct gctgaaaggc gagaaacctg
     7141 ctgtagcaac agcgattcgt gagcattaca tgcctatatc cagtgaagga gagctacctc
     7201 agtctacagt aggttctgtt ttagcgattg cagataaatt agatagcatt ttttctttct
     7261 ttgcagttgg gatgattcca agcgggtcaa acgatcctta tgccttacgt cgccaagcat
     7321 acggtgtcgt tcggatcatc gaatcgaaaa aatgggcctt tcctttgtct gttctgcaag
     7381 aaacgattag tgatgttatc agtaaagata cggatcgttt cggcattggt ttatcagaag
     7441 ggcaacaaca ggtgatcgac tttatcaaag gccgtctgcg ccaattattg acaacgaaga
     7501 atattcgtca tgatgtcatc gaagctgttt tgaatgcaga acaaaaagat ctgacaaaag
     7561 tatttgcagc agcacaattg ttcaagcagc atcttgcaga tgaagacttc aaaccatcga
     7621 tggaagcttt gacacgtgtc gtgaacttag cgaaaaaagc ggagcttgaa aaacaatcag
     7681 aagtagaccc tgaactgttc gaaaatgaag cggagaaaga actgcacaaa gcagtagagg
     7741 caatgaaaaa aagctttgct gaccaaacga tcaacgaaaa ttatgatcag cttgtaagcc
     7801 ttcgcccact gatcgaaaat tattttgatc agacgatggt catggcagaa gaaccagcag
     7861 tacgtaagaa ccgattaacg caattaagtc aaattgctgc catggctttg tcgctagcaa
     7921 gtttagatca aatcatcaca aaataatttc taatatgtaa ataaaccaga gaataggcac
     7981 aaaataggct atttctctgg tttatttgtt ataaatataa ataactatac ccgtggtgct
     8041 agttaatttt ttcctaggta ttatacaagt aatttgagtc ggtcaatttc aactgaatta
     8101 tctaaactaa ctgatctact tttagataat tcagttgaaa tttattg
//
LOCUS       DACGEU010000110         8111 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.113, whole genome shotgun sequence.
ACCESSION   DACGEU010000110 DACGEU010000000
VERSION     DACGEU010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8111)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8111)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8111
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.113"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            398..1126
                     /locus_tag="IXR40_002506"
     CDS             398..1126
                     /locus_tag="IXR40_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAQ4362304.1"
                     /translation="MESSNKGKSLYYQLVDLLKDRIETQMTPHDKLLSERELCQHYGV
                     SRTTVRLALQELENQGYIYRRHGKGTYVSDLSDKSSNLAGAYSFTEEMREIGRVPKTV
                     ILEFRQMEANKRIAKNLNIHLGETVFKLKRLRLADEEPLMVERSYLPAKLFMGLDLPL
                     LESKPLYDVFSQDYEQQVQLADEEFYASIVQKKDAVVLRIADGAPVLHLTRITYNVKN
                     EIIEYTDSVARADQFHYKIRHIRK"
     gene            1144..2340
                     /locus_tag="IXR40_002507"
     CDS             1144..2340
                     /locus_tag="IXR40_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAQ4362305.1"
                     /translation="MFELSKNKLKQIGAAITTQEIKQQPDLWKETIDRLMQSQENLAL
                     FFDQIKKEANGRRIRVIFTGAGTSQYIGDTLLPYLNEHGDNQFFIFHSFGTTDIVASP
                     KEFLFPNEPTLLVSFARSGNSPESVAAVQIANEQVETLFHLTITCAKEGMLAKNAQDD
                     KQNYLLLMPERANDAGFAMTGSFTCMLLSALWIFDQTAMEKKERYLEQLVKIGQDLLS
                     RDQEIQKLLPDFFERIAYLGSGSLAGATREAQLKILELTAGKVATIFDSSMGFRHGPK
                     SFLNSETLVVGFVSNQPYTRNYDLDILEEIKEDRVTANVIAIAQPGTIDFSGMTVLLE
                     DSVSKLPDAYLALAMIMTAQIIALYTSIKVANKPDTPSPTGTVNRVVKGVIIHKYETE
                     GEMTDE"
     gene            2333..3328
                     /gene="lacD"
                     /locus_tag="IXR40_002508"
     CDS             2333..3328
                     /gene="lacD"
                     /locus_tag="IXR40_002508"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HAQ4362306.1"
                     /translation="MNEEKNRAMERLSTKDGIISALAIDQRGALKKMIKSLGKEPSED
                     QISEFKELVSAELTPYASAILLDPEYGLPAAKVRAKETGLLLAYEKTGYDATTPGRLP
                     DLLADWSSLRLKEQQADAVKFLLYYDVDEAPEINHLKHVFIERLGSECEGENRPFYLE
                     LVSYDAQISDSSSPEYAKVKPHKVIEMMKEFSDPKYKVDVLKVEVPVNMNYVNGYSTG
                     EFIHSKEEAAAFFKEQSEATPLPFIFLSGGVSTELFQQTLIFAHESGSTFNGVLCGRA
                     TWKDGVKAYVENGKDGAIHWLRTNGRENIETLNKVINETATPWFNKTKSKKVKMK"
     gene            3325..4266
                     /locus_tag="IXR40_002509"
     CDS             3325..4266
                     /locus_tag="IXR40_002509"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hexose kinase"
                     /protein_id="HAQ4362307.1"
                     /translation="MITTVTLNPSIDIAYTIEELNLDKVNRVETVNKTAGGKGVNVAR
                     VLNLLGEEVIATGLIGGQHGEYLKNQLDQLGIMHQFVPIKGETRDSIAILHSSRQTEL
                     LERGPFITKKEQQTFTDHFEQLLEISDIMTISGSLPQGCPLDYYKQLVALADKKGKDI
                     LLDTSGKFLLEVLEGKEKPLLIKPNLEELGELIGQRICSSIQLEKIQSLLAHPIFEGV
                     PWVVVSLGERGAVAKVAQCFYEVIIPKISVVNPVGSGDATLAGSAHALSKRQSIEEIL
                     AFSMACGMANAQQEKTGWIDPMKVTMLMKHIQVKKIK"
     gene            4442..4921
                     /locus_tag="IXR40_002510"
                     /pseudo
     CDS             4442..4921
                     /locus_tag="IXR40_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724290.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
     gene            4934..5824
                     /locus_tag="IXR40_002511"
     CDS             4934..5824
                     /locus_tag="IXR40_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4362308.1"
                     /translation="MDIQWWQILLLTLYAGYQILDELQIYSSMSAPVFAGLYAGLVMG
                     DLNAGLIIGGSMQLTVLGVGTFGGASKIDANSGTILATAFSISLGMNPEQAIAAIAVP
                     VASLMIQLDILARFANTYFAHRIDRHVEDMNYQAIERNFLMGALPWSLSRMIPVFLAL
                     AFGGGLVENVVSVLNGNLKWLGDGLSVAGAVLPAVGFAILLRYLPVKKHLSYLILGFT
                     ITALLATLFSNVQLLGTSVASVVKDLPATFNSLPMLAVALIGLALAMISYKNDQNKDH
                     QPLASEPSHSVEGEIEDDEI"
     gene            5811..6620
                     /locus_tag="IXR40_002512"
     CDS             5811..6620
                     /locus_tag="IXR40_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAQ4362309.1"
                     /translation="MTKSNYKLTKEDFKQINRRSLFTFQLGWNYERMQGSGYLYTILP
                     QLRKIYGDNTPELKEMMKTHTQFFNTSNFFNTIITGIDLAMEEKEGIASKETVSGLKA
                     GLMGSFAAIGDSVFAALIPTIFGALAANMATDGNPIGVFIWIFAQIVVMVFRWKQLEF
                     AYKEGISLVTTMQSRLTALTDAATLLGVFMVGALVATMINVKFSWAPTIGDVTLNMQN
                     YIDMILPKILPAGIVGGVYWLLGKKNMTPTRAIFIVLIVCVALSALGVISK"
     gene            6634..7035
                     /locus_tag="IXR40_002513"
     CDS             6634..7035
                     /locus_tag="IXR40_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HAQ4362310.1"
                     /translation="MSRQLVLISHGKFCEELKKSTEMIMGPQEDIYTLPLLPEDGTET
                     YKQKFLTVTDSLNDFVVLCDLLGGTPANIISKLIMEGQQITLYAGMNLPMVIEFINSQ
                     MIGSEPEFVRAGCESIVSVNELINGIAEEEE"
     gene            complement(7081..8031)
                     /gene="yidC"
                     /locus_tag="IXR40_002514"
     CDS             complement(7081..8031)
                     /gene="yidC"
                     /locus_tag="IXR40_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HAQ4362311.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVVIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVMMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTESAKPANNKQATKQIKQPKNSTNNKGRNAGKQQKRK"
BASE COUNT         2612 a         1325 c         1749 g         2425 t
ORIGIN      
        1 atttaaaaaa atgtttgtca aattttatag aaaaaaagta taaaactgca aaagttatct
       61 aaaactaata ataacatttg tcattaataa gctattttta gttgttgtaa atgatattgg
      121 aagtaataaa acgatagttg taggaatatc atagggatta atgtggatca cgctgctcga
      181 taagttagac cattttgacg gatcgcttat gtggttcgtc tttttttctg ttcttttatt
      241 ggtaactggt atttttgagg tatctttgtc tattcaagat ataaagcttt aaagagctgt
      301 tataatagct tttttggtct aaaaaacctt tgacaaatga ttaataattc actattcttg
      361 tgttgtggtt ataaccagta aagaagaggt gatttttatg gagagctcaa ataaaggaaa
      421 atcattgtat tatcaactag ttgatttatt gaaggatcgt atcgaaacac agatgactcc
      481 gcatgataag ctgttatctg aaagagaact ttgtcaacac tatggggtga gtcgtaccac
      541 cgtacgtctg gctttacagg aattggaaaa tcaaggttat atttaccgaa gacatggaaa
      601 aggtacctat gtctctgatt tgtctgataa gtcatcgaac ttagctggag catatagctt
      661 tacagaagaa atgcgcgaaa tagggcgcgt ccctaagacg gtcattttag aatttagaca
      721 aatggaagct aataagagaa ttgctaagaa tttgaacatc catttaggtg aaactgtatt
      781 taaacttaaa agattgcgtt tggcagatga agagccattg atggttgagc gttcttatct
      841 accggcgaaa ctatttatgg gacttgattt gccgttactt gaaagtaaac cgttgtatga
      901 tgtgttttca caggattatg aacaacaagt tcaattagct gatgaagagt tttatgcaag
      961 tatcgtgcaa aaaaaagatg ctgttgtgct acgaatcgct gatggcgctc ccgtcttaca
     1021 tctgacgagg ataacctata acgtgaaaaa tgagattatc gaatatacag atagtgtagc
     1081 aagagcggac cagtttcatt ataaaattcg gcatatccga aaatgattga gagggagaac
     1141 aacatgtttg agctatcgaa gaacaaatta aaacaaatag gtgcagcaat cacgacacaa
     1201 gaaataaaac aacaaccaga tctctggaaa gaaacaatcg atagattgat gcaaagccaa
     1261 gaaaatttag ctctattttt tgatcaaata aaaaaagaag caaacggaag aagaatacgt
     1321 gttattttta cgggtgcagg aacgtctcaa tatattgggg atacgctctt accctatcta
     1381 aatgaacatg gagacaatca gttttttatc ttccacagtt ttggcacgac agatattgta
     1441 gcttcaccaa aagaattttt gtttccaaat gaaccgactt tattagtttc atttgctcgc
     1501 agtggcaaca gtccagaaag tgtagcggct gtgcaaattg caaatgaaca agttgaaaca
     1561 ttgtttcatt tgacgattac ttgtgctaaa gaggggatgt tggcaaaaaa cgcacaggat
     1621 gataaacaga attatctgtt attgatgcca gagagagcaa acgatgcagg ttttgctatg
     1681 acaggaagtt ttacgtgtat gttattgagt gctttatgga tctttgatca aacagcaatg
     1741 gagaaaaaag aaagatatct tgaacaatta gttaaaatcg gtcaagatct tctttcaaga
     1801 gatcaagaaa ttcaaaagtt attacctgat ttttttgaac ggatcgctta tctgggttca
     1861 ggaagtttgg caggtgcgac aagagaagca caattaaaaa ttttagaatt aacagcaggt
     1921 aaagttgcta caatttttga ttcttcgatg gggtttcgtc atggaccaaa gtctttttta
     1981 aatagcgaga cactcgttgt aggttttgtg agcaatcaac catatacgcg aaattatgac
     2041 ttagatattt tagaggaaat aaaagaagat cgggtcactg ccaatgtcat tgcgattgcg
     2101 caaccgggta ctattgattt ctcaggtatg actgtgctat tggaagactc ggtgagtaaa
     2161 ttgcccgatg cctatcttgc attagcgatg attatgactg cacaaatcat tgcactctat
     2221 acttcaatca aagtagctaa taaaccagat acaccatctc caacaggcac ggtcaatcga
     2281 gtagtcaagg gcgtcattat tcataagtat gaaaccgaag gagaaatgac agatgaatga
     2341 agaaaaaaat agggcaatgg agagactatc aacaaaagat gggattatta gtgcattagc
     2401 gatcgatcag cgtggtgctc taaaaaaaat gatcaaatcg ttgggaaaag agccaagtga
     2461 agaccaaatc agtgaattca aagaactagt atcagctgag ctgacaccct atgcttctgc
     2521 tattttattg gatccggaat atggattgcc agcagcaaaa gtcagagcaa aagagacggg
     2581 gttattgtta gcttatgaga aaaccggcta tgacgcaact acgcctggtc gtctacctga
     2641 tttattagcg gattggtctt ctctcagatt gaaagaacag caagcggatg cagtaaaatt
     2701 cttactttac tacgatgttg atgaagcacc cgaaatcaat catttgaagc atgtgttcat
     2761 cgaacgttta ggtagtgagt gcgaaggaga aaatcgtccc ttctatttgg agttagtttc
     2821 ttatgacgca caaataagcg atagttcttc tccagagtat gcgaaagtca agccccacaa
     2881 agttattgag atgatgaaag aattttctga tccaaaatat aaagttgatg tgttgaaagt
     2941 agaagtacca gtcaatatga attatgtgaa tggctattcc acaggtgaat ttattcacag
     3001 caaagaagag gctgctgcct tctttaagga gcaaagtgaa gcgactccat taccattcat
     3061 ttttttgagt gggggtgttt caacagaatt atttcaacaa acactgattt ttgctcatga
     3121 atcgggttcc accttcaatg gtgtattgtg tggacgtgcg acatggaaag atggggtcaa
     3181 agcatacgtc gaaaatggaa aagacggagc tattcattgg ttaagaacaa atgggagaga
     3241 aaacatcgag actttaaata aagtaataaa tgaaaccgct accccttggt tcaataaaac
     3301 aaaaagcaaa aaggtgaaga tgaaatgatt acgacagtta ccttgaatcc ttccatcgat
     3361 atcgcgtata caattgaaga attaaacctc gacaaagtca atcgagttga aacagtcaat
     3421 aaaacagcgg gaggaaaagg agtgaatgtg gcgagggttc taaatttatt aggagaagag
     3481 gtgatagcta ctggtttaat aggtggccag cacggtgaat atctaaagaa ccagctagat
     3541 cagttaggga tcatgcatca gtttgttcca attaaaggag agacaaggga ttctattgct
     3601 atcctgcata gttcgagaca aacagagctt ttggaacgag gccccttcat aacaaagaaa
     3661 gaacaacaga catttaccga tcatttcgag cagctcctcg aaatatcaga tattatgacg
     3721 atctcaggta gtttacccca aggatgccct cttgattact ataagcaatt ggttgcttta
     3781 gctgataaaa aagggaaaga catattacta gatacttctg gtaaattttt gcttgaagta
     3841 ttggaaggta aggagaagcc actacttatc aagcccaatc tggaagaatt aggagaactg
     3901 attggccaac gtatctgttc ttcgattcaa ttagaaaaaa ttcagtcctt attagctcat
     3961 ccaatatttg aaggagtgcc atgggttgtt gtttctttag gagagagagg tgctgtggca
     4021 aaagttgctc agtgttttta cgaagtcatt attcctaaaa tatcagttgt taatcctgtt
     4081 ggttcaggtg acgcgaccct tgcaggatcg gcccatgcgt tatcaaaaag gcaatcaatc
     4141 gaagagattc tcgcattttc tatggcttgt ggtatggcaa acgcgcaaca agagaaaact
     4201 ggctggatcg accctatgaa agttacgatg ttgatgaaac acattcaagt taagaaaatc
     4261 aaatgaactt aaatataaaa gaaagcgttt tctttagttg ggaaggaatt tgttcttagc
     4321 ttaaaaatga aatataagaa agaaaaaatg aaaacgttat ctttgaaaca gaagggatat
     4381 ttgatgatgt cacagtttta attgaacaat aaatagaaaa aatagataag gagaatgcat
     4441 gatggcaatt attggtgtaa gaatcgatgg acgtttgata catggataag tagcaaatct
     4501 ttggacaacg aaactgaata ttagtcgaat catggtcgtg gatgatgagg tagccacaaa
     4561 cacaattgaa aaaagtggat tgaagttagc gactccagca ggggtaaaat taagcatttt
     4621 gccaatcgaa aaagcagcaa caaatatttt agctggcaaa tatgactctc aacgagtatt
     4681 gatcgtagca aaaaagccag atcgaatctt atctttagta gaaaaaggag ttcctatcaa
     4741 agaagtaaat gtggggaata tgtcacaaac gaatgaaaca cggtccatta caaaatcaat
     4801 caatgtggta gatgcagata tcgaagtatt taaaaaatta gatcagcttg gtatacattt
     4861 aattgctcaa atggtaccaa acgataaagc agaagacttt atgaatcttt taatcaaata
     4921 ggaggaatga tccatggata ttcaatggtg gcagatctta ttattaacat tatatgcagg
     4981 ttatcaaatt ttagatgaat tacagatcta ttcttcaatg agtgcgccag tgtttgcagg
     5041 gttatatgca ggtttagtaa tgggtgattt aaacgcaggt ttgattattg gtggcagtat
     5101 gcagttgaca gttttaggag tggggacgtt tggaggcgca tcaaaaatag atgccaactc
     5161 tgggacgatt ttagcaactg ccttctcgat ttctcttgga atgaatccag aacaagcgat
     5221 tgctgctatt gcagtgcctg tagcaagctt aatgatccaa ttggatattt tagctagatt
     5281 cgctaacaca tactttgccc atcgtattga ccgtcacgta gaagacatga attatcaagc
     5341 aatcgaacgc aatttcttaa tgggagcttt accttggtcg ctctctcgta tgattcctgt
     5401 atttttagct ttagcatttg gtggtggatt agttgaaaat gttgtttctg ttttaaacgg
     5461 gaatctaaaa tggctaggcg atggactttc agtagcagga gctgttttac cagctgttgg
     5521 gtttgccatt cttctgcgct atttaccagt aaaaaaacat ctatcttatc ttattttagg
     5581 atttacgatc acggcattat tagcaacgtt attctctaat gttcaattat taggaacaag
     5641 tgtggcaagc gttgttaaag atcttccggc aactttcaat tcgctgccga tgcttgctgt
     5701 agcattgatt ggtctagcac tagcaatgat cagttataag aatgatcaaa acaaagacca
     5761 tcaaccatta gctagtgagc catcacattc tgttgagggg gaaatcgaag atgacgaaat
     5821 ctaattacaa attaacaaaa gaagatttta agcaaatcaa tcgaagaagt ttgttcactt
     5881 ttcaattagg ttggaactat gagagaatgc agggttctgg ctatttatat actatcttgc
     5941 cacaactaag aaaaatatat ggagacaata caccagaatt aaaagagatg atgaaaacac
     6001 atacgcaatt ttttaatact tctaattttt ttaatacaat cattactggg attgatcttg
     6061 caatggaaga aaaagaggga attgcttcaa aggaaaccgt atcggggctg aaagctggat
     6121 tgatgggttc ctttgcagcg attggagatt ccgtatttgc tgctttgatt ccaacgattt
     6181 ttggggcttt ggcggcgaat atggcaactg atggaaatcc gataggtgtg tttatatgga
     6241 tttttgctca gatcgttgtc atggtttttc gttggaagca acttgaattt gcatacaaag
     6301 aaggaatttc cttagttact actatgcaat ctcgcttaac tgcattaacg gacgcagcca
     6361 ctttattagg ggtattcatg gtaggggcat tagttgcgac aatgatcaat gttaaatttt
     6421 catgggcacc aacgattggc gatgtgacat tgaatatgca aaactatatc gatatgatct
     6481 tacctaaaat tttacctgct gggatcgtcg gtggtgttta ttggttatta ggaaagaaaa
     6541 acatgactcc tactcgagcg atttttatcg tattaattgt gtgtgttgct ttatctgcat
     6601 tgggtgtgat ttcgaaataa gggagagcga aaaatgagta gacaattggt attgattagt
     6661 cacggaaaat tttgtgagga attgaaaaaa agtacagaaa tgatcatggg gcctcaagag
     6721 gatatctaca cgttaccttt attaccagaa gatggcactg aaacatacaa acaaaagttt
     6781 ctcactgtca cagattcgtt aaatgatttt gtggtactat gcgatctttt aggtggtaca
     6841 cctgcaaata tcatttctaa actaataatg gaaggacaac agattactct ttatgctggg
     6901 atgaatcttc cgatggtcat tgaatttatc aactcacaaa tgattggttc agagcccgag
     6961 tttgttcgtg caggatgtga aagcattgtc tctgtcaacg aattaattaa tggaatagca
     7021 gaagaggaag agtaacaaaa aagatgaggg cttagctctc atcttttttg tcctatgttt
     7081 ttatttccgc ttctgctgct ttcctgcgtt gcggcctttg ttgtttgtac tgttttttgg
     7141 ttgtttgatt tgttttgttg cttgtttgtt gttagctggc tttgctgatt ctgtcacgtc
     7201 ttttcttgga gtgacgactt gttttggcgg gttttgtttc aactcttctg ccacttgtgc
     7261 tttcaaacgt ggtttcatca taacgtttgt gatgaatgtt tgcagacagc tgaacacacc
     7321 accgactacc cagtaaagtg taacaccggc tggcgcactg atcgacatga agacgatcat
     7381 agcaggagag acgattagca tcgtacgcat cgtctttttc tgttcttcag gaataccgat
     7441 cgttgagatg tatccttgaa gcagataggc gacccctgca atgacaacaa gtaccatact
     7501 tggtgagcct aaatcgatgc cgtagaaaga tgattcccga ataccttctg tataacgtgc
     7561 cgtaaagtac aaggcagaga agatcggcat ttggatcaat agaggcagac agccgattcc
     7621 gccggtcata ctcaatccgt tttcgcggta tacttgctgc atttctgctt gtgctgccat
     7681 ttgttcttca cgtgttgttg cagctttcaa tttttgttgg gctgcttcaa cttgtggttt
     7741 taacgcttgc attttttcag attggatcat tgtttttttc gattgactaa tacctagtgg
     7801 caagatgatg atacggacga tcacagtcat tgcaataact gcccagccat aagaccaatt
     7861 gaaattctca actagatatg taatcgcttg gcccatagga tggacgagta ctcgataaac
     7921 gattcccgaa gtgtcagggt ttccgtttga atccatccgc acacagccag ataaaaagag
     7981 caggatactg acaagtccgg atcccaataa ccagtttttc catttattca tagaatactt
     8041 cctcttctat aatttttaca caaacttaac tatactaaaa aagcgcatgg aattcaatca
     8101 acttcataga a
//
LOCUS       DACGEU010000111         7964 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.114, whole genome shotgun sequence.
ACCESSION   DACGEU010000111 DACGEU010000000
VERSION     DACGEU010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7964)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7964)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7964
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.114"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            11..1648
                     /locus_tag="IXR40_002515"
     CDS             11..1648
                     /locus_tag="IXR40_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HAQ4362312.1"
                     /translation="MKKNKNQIIDIIFMLFLSFAYVIPLFMSMGIYHSVNQDTYFHLS
                     RIIGLDNVWSSPVNFNNFDHHGTMMNIFYPWLTLYPAFLFYKMMGNLVLSYNIYYFFI
                     TFLTMVVSYFSMKQIKNNRYISLLFSIIYTFSAYRAIDIFHRASLGEAVALTFLPLIL
                     MGCYEIYIRDYQKWYWLSIGMTLVVYTHLLSVAMVSVFIGGTLFLSFYFWDQKIARLL
                     SLLKATVLTFFLSAGFLIPFIQQSRAQELKVPLGKELSGMAPSDMLTHILNNNYNNYT
                     IGLFLFLGLIGAFIFIKKLTADDLFIFFLGVFVLFCSTNLFPWQLFNHTPVKSLQFVW
                     RLNGFSSLFIAYTMSIVIYYIFSTKNNSWKIMVFTFLALILHLSGVSNSIHANKDSLT
                     LIAPEDAVAIAENYNHTDYANKESIYHPDMINNDQYLLGNQEINPTTHFMSNKLTIEL
                     DNSNNKNTVLTTPIYRYKGQVASINGKLVQTKLSKFGTTELTIPPGINKVVITYQYTK
                     LAIASRYLSIVTLILFLLYRFTFSKQKQPRREVQHSH"
     gene            complement(1793..2533)
                     /gene="truA"
                     /locus_tag="IXR40_002516"
     CDS             complement(1793..2533)
                     /gene="truA"
                     /locus_tag="IXR40_002516"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HAQ4362313.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYR"
     gene            complement(2724..3359)
                     /locus_tag="IXR40_002517"
     CDS             complement(2724..3359)
                     /locus_tag="IXR40_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HAQ4362314.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIAWLSILHLKQ"
     gene            complement(3506..4747)
                     /gene="sstT"
                     /locus_tag="IXR40_002518"
     CDS             complement(3506..4747)
                     /gene="sstT"
                     /locus_tag="IXR40_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HAQ4362315.1"
                     /translation="MLEKFLDMSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSC
                     LKAIAPILVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPIT
                     LQETVSEKAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSEST
                     KELVDQISIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLF
                     VALVVYPFLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKE
                     SYSISIPLGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGV
                     AGGSLLLIPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELG
                     ARKRSGEKIKLKDCLDGLSER"
     gene            4945..5941
                     /locus_tag="IXR40_002519"
                     /pseudo
     CDS             4945..5941
                     /locus_tag="IXR40_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302657.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            5957..>7964
                     /locus_tag="IXR40_002520"
     CDS             5957..>7964
                     /locus_tag="IXR40_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HAQ4362316.1"
                     /translation="MSLLVIFLFYIQKIRFIHRFIEYFAFDSIEQLTQRWKKRIHWLF
                     VHKSYFLVAAFFYCFTFVQIFVLEPKEGWKETIQVALKIFTQRQAPMILTIIIIMGFF
                     FLLLLISNRFWYALTATLIINLLLTISTVIKMEMREEPVFPSDLKILTGLSELLSMVS
                     PVLLIVGGLILLLLLITSIIVQRRLQKQYSLKIHWKRRFISIAVLLGCFSGVFFINHK
                     NSPSFLLFNLFKVNKTFFNQQGAVKDNGPVIQFLNNIDIKIMEEPAGYSKEKINGIMK
                     KYNTKADEINQTRSDWLNNQTIVLNLSESFSDPARVPNLTVPTDPIPYIKSIITEGTG
                     GLMLSVGYGGGTANMEWEGLTGLSISNLSASLVTPYTQLVERQKISPNITDLFDEKIA
                     IHPFTAALYRRKQVFDKFGFDRFYYLDSPDKLTYTDKIEQSPRISDDSAYKETLKALQ
                     SNTETSQFIQLSTMQNHMPYDDYYSELNYTAEGTAVIPNRRKELQTYMQGLHYTDTAV
                     KKFIQEIDKIDKPITFVFYGDHLPAIYSGNDSKKYGLEQHQTDYFIYNNKYSREQAAT
                     LNKEVVAPNNFGAMALEHANIKVTPYYALLTEVSNHLPALTIDPTESLSNRFNGKQVF
                     VTEDSQIIQEKNLTEKQKEILEDYRLIQYDLVAGNQYSATWATQK"
BASE COUNT         2608 a         1492 c         1238 g         2626 t
ORIGIN      
        1 ggagaaaaaa atgaaaaaaa acaaaaacca aataatagat atcattttta tgttatttct
       61 aagttttgct tacgtcatcc ctctattcat gtctatggga atctatcata gtgtcaatca
      121 ggatacttac tttcatttat ctcgaatcat aggactagat aatgtatgga gttctccagt
      181 aaacttcaat aacttcgatc atcatggaac aatgatgaat attttttatc catggcttac
      241 tctttatcca gcttttttat tttataaaat gatgggaaat cttgttttaa gttataatat
      301 ctactatttt tttatcactt ttttaacaat ggtcgtttct tatttttcta tgaaacaaat
      361 aaaaaacaat cgttatattt cgctgttatt ttcgattatt tatacatttt ccgcctatcg
      421 tgccattgac atattccatc gtgcttcatt gggagaagct gtcgctttaa catttttgcc
      481 tttgatacta atggggtgtt acgaaattta tattagagat taccaaaaat ggtactggtt
      541 gtctattggc atgacgctag tagtgtatac tcatttactt tctgtcgcta tggtttctgt
      601 atttattgga ggaacgttgt ttctttcttt ttatttttgg gaccaaaaaa tcgctagact
      661 cttaagtctt ttaaaagcta ccgtcctcac ctttttttta agtgcgggat tcttaattcc
      721 ttttattcaa caatctagag cacaagaatt gaaagtccca ctgggaaaag aattaagtgg
      781 tatggctcct agtgatatgc tgacacacat tttaaataat aactataaca actatactat
      841 tggattattc ttatttctcg gattgattgg tgcttttatt tttataaaaa aattaactgc
      901 tgatgattta tttattttct ttcttggtgt atttgttctt ttttgttcaa ccaatttatt
      961 tccttggcaa ctttttaacc atacaccagt taagagtcta caatttgtct ggcggttaaa
     1021 tggtttttct tctttattta tagcctatac gatgagtata gtgatctatt atattttttc
     1081 tactaaaaat aattcatgga aaataatggt ctttacgttt cttgcactaa tattgcatct
     1141 ctcaggagta agcaattcta tccatgctaa caaagattca ttaacactta tagcacctga
     1201 agacgctgtt gctatagctg aaaattacaa tcatactgat tatgcaaaca aagagtcaat
     1261 ctatcatcct gatatgatta ataatgatca atatttacta ggtaaccagg aaataaatcc
     1321 aacaactcat tttatgagta acaaacttac aattgaatta gataattcga ataataaaaa
     1381 tactgtcttg acgacaccta tttatcgtta taaagggcaa gtggcttcta ttaatggcaa
     1441 actagtacaa acaaaattat ctaagtttgg cacaactgaa ttaactattc ctccaggtat
     1501 aaataaagtc gttattactt atcagtacac aaaactagca attgcttcaa gatatttatc
     1561 tatcgttact ttgattttat ttttacttta tcgatttact ttttctaaac aaaaacaacc
     1621 gagaagagaa gtacaacatt ctcactagat ttttatttaa gaaagacttt ttagctgtac
     1681 acataaacag gctaaaaagt ctttttttat atttctttaa tttgcttcat acattattta
     1741 acatcgatat ttatactgtg aaacatgcgt ttcatccatt atcaaagtat ttttatcgat
     1801 aataaacttc atccaaaaac agaccttgtg cagggacggt ttctcctgca tgttgccgca
     1861 ctttgctttc aaatatttca tcgattgttt ctatcggcat ggcacctgtg ccgatttcta
     1921 gtaatgtccc catgataatc cgcaccattt tatataagaa tccgtctccg acaaaagtaa
     1981 aatgaagcat ttctcccttt cgttcgatag ataattcatc aatcgtacgc actgtggatt
     2041 tttttgattt tttcaatgca gaaaaaccaa tgaaatcatg tgtacccact aatttttcgc
     2101 aagctgcatt cagcttgtcc atatccaact cttgagggaa ataaaagctg tggtttcgct
     2161 caaatgctga aggaatcacg ttgttccaaa cataatagct gtattttttg cccaccgcat
     2221 tatatcttga atggaagcgc tcaggcattt cttcgattct tttgatgaca atatcccgcg
     2281 gaaggtaacg attcataaag tcgatcattt ctgccagtcc aatttctgtg tttgttttaa
     2341 aatttgctac ttgtcctcgc gcatgggtgc cagcatctgt tcttcctgat ccaataattt
     2401 ctatctcttc atttgtcatc tgatgcaata ctttttcgat ttttccttga atggttttat
     2461 cgtcatctcc aagtctttgc catcctgaat atctttttcc gtcatattcg attgtcaact
     2521 tgatgtttct catattttag tggctcctct gtcttccatt tggtcttctc tctacctttt
     2581 taagattgta gcacaaaata tagctccttt cttctctaaa acagaagcta tacaagaaaa
     2641 ctgtggaaat atatatttca gaaaaacaaa aaacagccac cggatgaagt atccgctgac
     2701 tgttcaattt gacggctcaa gttttactgt ttgagatgca agatactcaa ccaggcaatg
     2761 ggcacataat taaagaaaaa actgattctt tggcaaaaac ctattttatt cagtaatggc
     2821 caagaattta tagaaggaat tcttgccagt ccataaatcg ccgcaaaaag caaactgatc
     2881 acagacagtc caaggtataa gtggcttacg tccatttgcc cattttttcg atagatcaag
     2941 aaaagaagaa ctggaaacaa taaaaaacca ctgtaaccta aacctgatcc gatattatgg
     3001 acccatgtcg agacattcca cgaagattca tgggtattga tactgaacaa acctgtaaag
     3061 atacaatcac ctataccata gaacgcgatg gctgctgtaa ctagggtagc taacacacga
     3121 gatgtactta caaatgcagc atacaatgca ggcaatgaca ggatgaaaaa gatccctgaa
     3181 accacagacc aaataagaaa cgcttttctt acaggactgg aaacctctcc aaatacactg
     3241 atcacgctct tcatttgatc taattcagga taatacaatc ctaatacgta cggagtcaaa
     3301 aaatcactca gcacgcctaa taataaaaag aaaaaaccaa atttacgtaa aaaatccatg
     3361 atacgcctcc aataacaatt acctatgctt ttaattgtta ttataagcga ctttatcttg
     3421 atttaacaga aacctctatt tacacgaaca tctatataac tcattaaaaa ctcgaatcat
     3481 tttaaaaata ctaaatatct aacgttcaac gttcacttaa tccatctaaa caatctttca
     3541 atttgatttt ttccccactt cttttacgcg cgcctagctc tcctattgca gtaaacaaca
     3601 gatcacttga cgaatttaag gcagtttcca ttgaatcctg gataacaccg ataataaatc
     3661 caataccgac gatttgcatc gcgacatcat tagagatacc aaacaaacta catgctaatg
     3721 gaatcaataa cagtgaaccg cccgcaacac ctgaagctcc acaagcagct aaagcagaca
     3781 aaatacataa aaggactttc aaaacaaaag gtgcttcaat ccctaaagaa tgtacagcag
     3841 tcaacgtcat caaggaaatg gtaatcgcgg caccgcccat attgatcgta gcacctaacg
     3901 ggatcgatat ggaataagac tcttttgtca atttcaatct ttcagccaac atcatgttta
     3961 tcgggatatt tgcggcagaa cttcgggtaa agaaagcggg aagtgcgctt tctttcaaac
     4021 aaaagaaaat caatggatag ggattttctt taataaacaa aaacgtgagg aatgggtaca
     4081 caactaatgc gacaaacagc atcgtaccga tcaaaacaag taaaagctgc agatactctg
     4141 ccaatccagc tattccagtc gtagcaattg attgataaac caatcctaaa atccctatcg
     4201 gagcaaatgc aataatcact tgtacgactt gtgacaacgc tatagatatc tgatccacca
     4261 actcttttgt cgattctgaa cgtgctcgaa aagctagtcc caacaataca gcccagaata
     4321 agacgccaag gtaattcgca tcaataagag attgaacagg attttgtgtg acattcgtca
     4381 acatagtaga taaaacactt tccaaacttt gcggtgcttt ttcagatact gtttcttgta
     4441 aagtaatagg aacagtaaaa attgaactta caataactgc tacaagtgca gaaagcaatg
     4501 ttcccactaa atataagatc aaaataggct tcacgaatgt cttattccca attttatgct
     4561 tggcaattga cgccatcgtc aagaaaaaaa ccagaatagg tgcgattgcc ttcaagcaac
     4621 tgacaaacaa cgttcccaat attgaaataa atgtccatgt ggggaaaaag ataccaaaca
     4681 atattccgac taaaatacca acaacaatac gttgaactaa cgacatatcc aaaaacttct
     4741 ctaacaaatg accacccttt cacaatttta acaatcattg tatcatttta tgcaaagaaa
     4801 ctaaaggtat aattttctaa aaattctaac aatacaaaca accatttctt gctaattttg
     4861 tactttttct gtctacacgt tgttttttga gatattctaa gttaggatgt tattaatggg
     4921 caacttatca ggaaacgttt tcttatgttt ttgtccaatt tttttgtgag gtgtttattc
     4981 ttgaaaaaaa taaagaagga gagttatggc ttcctgacaa tctttgtcgc ttgtataatg
     5041 atggttttac agcgtatatt gatttcagca gtcactattc ctacatatgc aacaaaccct
     5101 ggtcgattct acatctatac atttttacaa acttccgttg ttattggtgc aaatttgatc
     5161 ccactttaca tgggttacca atatcaaaaa atcgcccgtt taaaagtttt acattattta
     5221 agtcgttttg cctttatatt cctaatagcc acactagttt gcaatatctt ttttttacgt
     5281 acaagctggc agcttgaata ttcgtgatta ttggcttatc ctaacaccta tcagtcagaa
     5341 ttactttact tatgctgttt cttgtacttt gcttttttgt agtattcctt atacagttgg
     5401 atttttaaat aaattatcga aaacaacaat taaatatcta ctattatttt taacaattgg
     5461 attagttggc tgctctactc tatttaataa agacccgttt gcattacaga atggacagag
     5521 tattttatgg attttttatt tatttttaat gggttatggt ttgaaagaat ggaactggaa
     5581 agaaaaggtc cgctataagc ttcctcaagt atttatcagc ttgattgttt tattcggttt
     5641 gattattttg atgacacaaa tttcactcat catcagagga aatacagata cagcgctgag
     5701 gttttctaaa ccatattctc tcttcgcaat gtattatact ttctcttcgt ttttattttt
     5761 agaaatgcta tctgataaat taggtataaa aggaagagga aattttcttg ctgtattttt
     5821 gattgtcact caagttatat gtaatttccc tttagtttct tatcgcgtat ctacatttat
     5881 gaaacgtgaa tttccaaact cagggaaggc atggctgata aatatcgggc agttttttat
     5941 ttgctattta ttagcagtgt ccctcctagt tatcttttta ttttatatac aaaaaatccg
     6001 tttcattcat cgtttcatcg aatacttcgc ttttgattcg attgaacaat taactcagcg
     6061 ttggaaaaaa agaattcatt ggctttttgt tcataaaagt tattttttag ttgcagcatt
     6121 tttttactgc tttaccttcg tgcagatttt cgttttagaa ccaaaagaag gttggaaaga
     6181 aactatccag gttgccttaa aaatatttac tcagcgacaa gcacccatga tcctgacaat
     6241 catcattatt atgggatttt tcttcttact attgttgatt tccaatcgtt tttggtacgc
     6301 cttgactgct accttgatca ttaacttact gctcactatt tcgacagtaa tcaaaatgga
     6361 aatgcgggaa gagcctgtct ttccttcaga tttaaaaata ctgaccggat tgtcagaact
     6421 attatcgatg gttagcccag tcttattaat cgtgggcgga ttgatccttc tcctattatt
     6481 gattactagt attattgtac aacgtagact acaaaaacag tattccttga agattcattg
     6541 gaaacgtcga tttatcagta tcgctgtatt attaggatgt ttttcgggtg tctttttcat
     6601 taatcacaaa aattcgcctt ctttcttgct gtttaattta tttaaagtaa acaagacttt
     6661 ctttaaccag caaggcgccg taaaagataa cggaccagtc attcaattcc taaacaatat
     6721 cgacattaaa atcatggaag aacctgctgg ctattcgaaa gaaaaaatta atggaataat
     6781 gaaaaagtac aacacaaagg cagatgaaat caaccaaaca agaagtgact ggttaaacaa
     6841 tcagacgatc gttctcaatt taagtgaaag cttcagtgat cctgcacgtg tccctaatct
     6901 gacagtacct acagacccta ttccttacat caaaagcatt ataacagaag gaacaggagg
     6961 attgatgtta tccgtcggtt atggtggcgg aacagctaac atggaatggg aaggactgac
     7021 aggcttgagt atcagtaacc tgtctgcttc gttagttaca ccttataccc agctagtgga
     7081 gcgtcagaaa ataagtccaa atattaccga tctattcgat gaaaaaatag ccatccatcc
     7141 ttttacagct gctctttatc gcagaaaaca agtgtttgat aaatttggtt ttgacaggtt
     7201 ctattattta gacagtccgg ataaattaac ttatacggat aaaatagaac aaagcccacg
     7261 catatcggat gattcagcat acaaagaaac cttgaaagct ttacaaagca atacagaaac
     7321 gtcacaattc atccaattat ccactatgca aaaccatatg ccttatgatg attactatag
     7381 tgaattgaac tacactgctg aaggaactgc tgtcattcct aatagaagaa aagaattaca
     7441 aacttatatg caaggccttc actataccga tacagcagta aaaaaattca tccaagaaat
     7501 cgacaaaatc gataaaccga ttacctttgt tttttatggt gaccatttac ccgcaatcta
     7561 tagtgggaat gattcgaaaa aatatggatt agaacagcac cagacagatt atttcattta
     7621 taacaacaag tatagtcgtg aacaagcagc tacgttaaat aaagaagttg ttgctcctaa
     7681 taactttggt gctatggctc ttgagcatgc gaatatcaaa gtaactcctt actatgcgtt
     7741 gttgacagaa gtatctaatc atctacctgc attaacaatt gatcctacag aaagcttgtc
     7801 taatcgtttt aatggaaaac aggtctttgt tacagaggat agtcaaatta tccaagaaaa
     7861 aaatttaact gagaaacaaa aagaaattct agaagattat cgtctgatac aatatgatct
     7921 tgttgcaggt aaccagtaca gtgcaacatg ggcgacacaa aaaa
//
LOCUS       DACGEU010000112         7825 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.115, whole genome shotgun sequence.
ACCESSION   DACGEU010000112 DACGEU010000000
VERSION     DACGEU010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7825)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7825)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7825
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.115"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(69..1490)
                     /locus_tag="IXR40_002521"
     CDS             complement(69..1490)
                     /locus_tag="IXR40_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAQ4362317.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(1733..3610)
                     /gene="tdc"
                     /locus_tag="IXR40_002522"
     CDS             complement(1733..3610)
                     /gene="tdc"
                     /locus_tag="IXR40_002522"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HAQ4362318.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(3901..5157)
                     /locus_tag="IXR40_002523"
     CDS             complement(3901..5157)
                     /locus_tag="IXR40_002523"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HAQ4362319.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     gene            5737..7038
                     /locus_tag="IXR40_002524"
     CDS             5737..7038
                     /locus_tag="IXR40_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HAQ4362320.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(7107..7706)
                     /locus_tag="IXR40_002525"
     CDS             complement(7107..7706)
                     /locus_tag="IXR40_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAQ4362321.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
BASE COUNT         2321 a         1598 c         1370 g         2536 t
ORIGIN      
        1 aaaactattc acttggcagg acctcctact aaatcagcga caaaacgtcg gctgaaagac
       61 ttattttttt atttttcttc taaacttttt tctacctcaa tcccccaaga atctttcttg
      121 aagtgattga tgatcaatgg aataacgaac atgaccactg tgatagctgc tactaataat
      181 gcatcactca atgtcgctgt acctaatgta gcaaatacga caacgatgat agagaagatc
      241 agcatgcagc tgactaccca agctaatccg tttccgtttt taccaattcg gtaaggacgt
      301 tcgaattctg gatgtttctt acgcatttta agcaatgaaa cagcaatcaa aatgtacacg
      361 atacaataaa taacagttgt agcatttgta agtgtcaaga atacagcact tacgtcatcc
      421 attacaccat aaagcaaagc aaataatgaa ataacgattg attgtgttag aacgacattt
      481 ctagatacgc cgtatttgtt ttctttatgg aatccgaatt ttggtggaag gaatccttca
      541 cgagctactt ggatgattgt ttttgatggt ccagtaaccc aagctgataa ttgtaaaagc
      601 acaccaataa ataccatgaa gctgaagata tttccgatca cttctggtaa gcctaggatt
      661 tgacagtcaa tcaagatagg ctgcgtgata tttgctaatt ccatttttcc atctggtacg
      721 acatttgcta caagcatcgc attgatgaca ttcaataaaa ctaatccgat caaagcgata
      781 aatacgcctt ttgtataatt ttttgttgcg tctttcaaac gaggcatgta aacagaactc
      841 atttcgatcc caacaaaaat aaatgtgata ccagctaagt atttcaatga atcaatatgt
      901 tccaagtcag ggaaagcttt tgaccatgaa aagtcaccta gatagccgtt tgagactagt
      961 ccgactttga aggctgccaa aacacctaaa acgaacatga tgactactgg gatatatacc
     1021 cctagccata caccgatgtt cccgccgact tttgccatat cgaatttcaa gttcaagatc
     1081 gtgatgatcc agtagataac taaaatacaa cctaaaacga accagtgatt attgccaagt
     1141 tctacattac caaatgtgtt tcctaacaat ggtcctaaag tagaagcgac cattaccata
     1201 cctgggaaca tttgcaccca taatagccat gcaacgacaa atccccattt gctgcccagt
     1261 gctgttttta cccataactg aggaccgcct tcttgaggaa gcatcgtgga aagctcaccg
     1321 gaaaccattg atatcggacc ggcaaaaaac aaaactgcaa aaattgaata aaaaatcaat
     1381 gtccaaccga ctgcggctaa cgtaggaata ctccgaaccg ttgcacacag tgccattgtc
     1441 agaccgataa aggtcccaag acccatttta cttacttcag atttactcac cgttgacact
     1501 ctccttgatt ttttggataa aataacggtg tctttgaagt agtttcagca ataaacgaaa
     1561 caattcagcg aatatttgag gggattcttt gagtttattg cttgaagggt ttcttcaaag
     1621 acaacctcaa aacaaaggga tcgaagagct taggtctccc cttgctcttc agatccaaac
     1681 atgcgtcaga aacagttagt attcaagctg ttttctaaca tgattacctt gcttattttg
     1741 cttcgcttgc caataattgg tctgcgtaga ttttttccaa tttttcttga agagctgctt
     1801 tgattttttc agcatattct tcaaagtgtt cttctttgtt catgtatggt gtcattacgc
     1861 tggcacgcaa tacagttact tttccggcac ggttccattc ttcatctgag aatcctagtt
     1921 ggttcacaaa ttgtaatggg ctgttgccat agtctgggat agcaaagtca gtatgtgaag
     1981 ttaagaactc attaccgtaa atgcttcctt tcacgtatga agaataatca tatacgtcat
     2041 ggttcaattt attcattgca actaagtcat cgttgccttt ttctttgaat acatagtcta
     2101 ccatattgaa atctggataa gttaatggat gaacttcgat ttctttgtct cctactttaa
     2161 atgacaagtc attcaagaag ttgtagaaac gatgtgcacc ttcgattgat gcacccatta
     2221 atttaccata tcctgtgaca ttcaaaggta agacatggtg tgctgcccaa acgctggctg
     2281 ctgttgcccc tgcttttgaa ccttccaaga tataagcccc aagtaatgct gggatatctg
     2341 cgcctttttc aaatacatat gtcgcaaagt aagagataac gtctctcatg cggatatctt
     2401 tgatgacgat accaccggca gaatatggaa catagcccat tttatgtggg tcaatcgtta
     2461 cagattctgc ttcttcgatt gctttatatg cactgtgtac ttcttctaag atataatctt
     2521 tgttttctgt aaagacattg tatttgtaat gaacatcttt taaatcttca aatggaatga
     2581 agttgttgtc ttcgtctaag aaaatcgcac ggccgtatcc gccataagca gcatctacgt
     2641 gtaagtagaa gtaaataccg tctttttcta atacgcgacg caatgcaacg attttatcga
     2701 taccgtcgat tgctccttct tctgttgatc ctacaacacc gactacacct aggattggtg
     2761 ttttttcagc tgctagacca cgaacgattt tttcaagttc gttgatgtcc atgcgatagt
     2821 tgtggtcaac tggcactgga atcacttggt ctaaaccgat accgatgatg tcggcagctt
     2881 ttagccatga atagtgttta gtttgtggaa ccaaccattt tcctaatttt tctaaatgtt
     2941 ttccgctacg tgctgagtga gctttgattt cgtcgatttt ttctgggacg ctgtctaaca
     3001 gattcatgat ttcttctgtt gacaagttca ttaattccca atcgcttttt ccagcaacta
     3061 gttcaggtgt cacttctttc attgcaagcg gcaatgattt gatgttgcgg gcataccaaa
     3121 gtccttctaa gtttgctaaa gaaccatcag caacgatgtg gccccagcca tctttatagc
     3181 tcattaattt tgcaaattcc attcctactt cttcttccat ttggcttgtt gcaggagaag
     3241 attcataggc aacgttatta ccattccata gcatagcaaa attgtacgct agtaaagatg
     3301 gcatcaatgt ttcagagttc atatgacccc agtaacgtcc ggcattatgc caaggaacgg
     3361 aatgggtacg catccgcgct gaaatttctg atagaacatc ctttgtttta ttcacagtgt
     3421 gttcaaaact agcactgctt ttttcttctg gcgtaataat aggcatgtct tgaggcatgt
     3481 agttttgacg ccagcctaaa tgttcatcca ccaattcatt caacaaagct ttatagattt
     3541 ggccgttctc agctttgtcc ccaatgaata gggcatttag gtttagatct ttcgacaatg
     3601 attcactcat agtgaaaccc tcctaaaaaa atatttaaat tttgtcgagc cctacattac
     3661 acctgttctt ctattctgta aactaagttt tggcctgatt tttaatcata ttttaatatg
     3721 tatcaattat ccgaattgtt cacacttttg aaataattaa aaaaaacgag ggaatttaca
     3781 aatgtaaact ccctcgcaaa gattgtatta acgacaacca gcgttctatt ttaggatggg
     3841 tttcaaaatt ggaatgttgt aatagtattt ccctttttca aggtaaaaac ttactaaatt
     3901 ctaatcaatt actttggcca aaaagtaatt tttcttacct tttcgaataa ccacaaactt
     3961 accatcgaat tcatcggatg gatttatgac aaaatttaaa tcggtaacgc ggtcaccgtt
     4021 aatacttata gctccgtttg aaacatcttc acgtgcttga cgtttagatg gttcaatttt
     4081 tgtggaaaca agcagttcca cgatattttc aggtgtgctt gaaatttcaa cgttcggcat
     4141 tttaccgaat ccttgcgcga tttcttccgc atttagttct ttaatatttc cagagaacaa
     4201 tgcttgcgtt attttttgcg cttctttcaa gtcttcttca ctatgcacaa atcttgtaac
     4261 ttcttctgcc aaacggcgtt gtgcttcacg tttctcaggt tctgtctcta cttttttcgc
     4321 taagtcttcg atttcttctt gagacaagaa agtaaagaat ttcaagtatt tcactacatc
     4381 gcgatcatct tgattcaacc agaattggta gaactcaaat ggtgaagttt tcttcggatc
     4441 aagccaaacg gcaccgcctg cagtttttcc gaatttcgtt ccgtcagcct tcagcatcaa
     4501 tgggatcgtt aaaccgaacg cttctgcttc tggtccttct aattttcgga ttaggtctaa
     4561 tccagctgtg atatttcccc attggtctgc tccaccgatt tgcaattgca catcgtatgt
     4621 tttatgcaga tgcaaaaagt cgatagattg caggatttgg taagtaaact ctgtaaatga
     4681 gattcctact tccaaacggc tggcaacgat atcttttgct aacatcgtgt tgatgttgaa
     4741 gtttttaccg tagtctctca aaaattcaag taaagagatt tttgacaacc agtcgtagtt
     4801 gttcacaaat gtgatatttg catctttacc aaacaatttt ctcatttgat tggaaagtgc
     4861 gtccacgtta tgttgcactt gttccatcgt ttgcaacaca cgttctgttt tgcggccgct
     4921 tgggtcgccg atcgttcctg ttccgccgcc aatcagaata tatggatgat ggcctgccaa
     4981 ttggaatctt ttcatcatca taaatggaat caaatgtccg atatgcatcg aatcaccagt
     5041 tggatcaacg ccgcaataaa gtgaaatgct cttttcttca acgagctcgc gaagtctttc
     5101 ttcgtttgtt tgctgattaa tggcgtcgcg ccaagttaat tcatcaataa tattcatttt
     5161 actgacctcc gtgtagtttt tttatgaaag caggaacctg ctagcatgtg taattaatta
     5221 tttcttcagg ataggatagg aaataaaaaa agtcccttgg catataagcc aagggacgaa
     5281 atctcgcggt accacccaat ttgtatgtct agatatccaa catacctctc gaacatttaa
     5341 cgctgtcgcg tggcaatcac tgccaaagac tcctgaaatg taattcgctt taaagcatgt
     5401 actggtttgc agcgaccacc agctttctga aacattggct ttaacaacta cttcgtttcg
     5461 atcttcgtct tgttattatt aatatgtgtc tatcatagag cgcaactttt tctttgtcaa
     5521 cagaaaaagg atattttttt taaattcctc attttttctt ttttgaatcc gctctaattc
     5581 cgaacatttt attttcaatt attgttaaaa gaaataactt tttctgtatt ttttctgcaa
     5641 tttatcgaga agtcacttta ctttgcctct tattctttct tcgttacaat aaggaatggg
     5701 acaagtaaaa aaatgaaaaa gcaagggacg aggtatatgg aaaaaaagca aaaaattatt
     5761 ttaggagcca cttctgcttt aactatcgtt attttaattc taagtttgtt ttttgtcatc
     5821 cgatcatcta caaaaaaaga accaatcatt cctgaaaaaa aaataacaga aaaagcaaaa
     5881 gaaccgacag atgataagca acaactagtt actcaagcaa aaaatctggc tcaaagctac
     5941 gattatgacc aagcgattgc gttattggaa aaagatagta agaacggatc tactgaaaca
     6001 caacagcttc ttcaaacact aaaaaaggag aaagaacaac tgatcgactg gtctgatcct
     6061 actcagatct ctcatgtctt tttccacagc ttgatcgtgg acccgcaaaa agccttccac
     6121 tctcaacagg cacaaggata caaagattat atggtgactg ttgaagaatt caaccgttcg
     6181 atcgaacaac tttatcaaaa tgattttgtt ttagttaatt tgaatgattt gatccaaaaa
     6241 gacgaacaag gaaatctttc ctttaacggg cttgcgctac ctgaaggaaa aaaaccattg
     6301 gttctttcac aagatgatgt cagctattat gaatatatgg ataattccgg ttttcctagc
     6361 cgattggtcg tatcaaataa caatgaaatc aaaaatgtct ataaagagaa agataaagaa
     6421 gaaatcggtg actttgacat ggttcctctg atcgatgcct ttgtcaagaa acatcctgat
     6481 ttttcttatc gaggcgcaaa aggtaccttg gccctgacag gttacaacgg agttttaggt
     6541 tatcgaacat caaaatctca atatggagac aatgaaaaaa caaaaaaaga gattaaagaa
     6601 gctaaaaaag tggcggaaca gttgaagaaa gacggctgga gctttgcttc ccatacatgg
     6661 ggtcacttga atatgactca agcttcacta gaagatgtaa aaaaagacaa tgaattgtgg
     6721 cagcaagaag ttgcacctat cctaggaaaa acaaatattc tgatttatcc atttggtgca
     6781 gacatcagcg actggcagcc ttattcagca gaaaatcaaa aatttgctta cttgaagagt
     6841 caaggtttcg atattttctg taatgtcgat gcttctacac cagcttgggg acaattaggt
     6901 acggatttct atcgaaatgc tcggatcaat atcgatggca ttcgttttca atctgattta
     6961 gacggaaaaa atcctattct tgatccattc atcaatgtcc atgatgtcta tgacaaagaa
     7021 gcacgcgaat ctgcttgatt ttacgtcatt tatgaaccaa aaaagccgaa ctgacatttt
     7081 atcgtcagtt tcggcttttt tatgctttat ttcttcttcg gtgcgattcc cttgatcagg
     7141 acttctgtcc attctgctgt atatggaagc agttttgcgt atatctccgg cttagaaatt
     7201 ccttctacca ttgcttgaaa atagaggatc aagaactcat ccgaatattt caaatccact
     7261 tttccttctt tccgccctcg atggaaaaga tcaagcatga tactgaaact ttcttgcgta
     7321 tacgcatcca tcgcgtcaga aaattctttt ttttcttttt ttgtatagta tgtcatcaaa
     7381 tcgatataaa attgtttgtt cactcgattg agataacgga ttttgttttc actcatggca
     7441 atcagtgttt cttcaaatgg aagattttcc gcaatcaacg ctttcgcttc ttgccctaaa
     7501 tcattcataa atgcaaaaaa tacttcataa atcagccctt ccttgctgcc aaaatattta
     7561 aaaatcgtcg ctttacttac ctgagcgttc tcagctacct tatccattgt cactccagcg
     7621 gttcctatgt ctgtgttcat caagtcaaaa gctgcttgta aaatctcttt ctttttctct
     7681 tgtgctctct tttcaaaacc gttcatttgt agagcctccc gtaattttaa acttttataa
     7741 tatatatagt tcaaatttat tctgaggttt attataacta tctattgaga aagtatcaag
     7801 ctagcaattc cttgtttatg aattc
//
LOCUS       DACGEU010000113         7803 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.116, whole genome shotgun sequence.
ACCESSION   DACGEU010000113 DACGEU010000000
VERSION     DACGEU010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7803)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7803)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7803
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.116"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(111..635)
                     /locus_tag="IXR40_002526"
     CDS             complement(111..635)
                     /locus_tag="IXR40_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4362322.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(628..1101)
                     /gene="tsaE"
                     /locus_tag="IXR40_002527"
     CDS             complement(628..1101)
                     /gene="tsaE"
                     /locus_tag="IXR40_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HAQ4362323.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(1224..2204)
                     /gene="pta"
                     /locus_tag="IXR40_002528"
     CDS             complement(1224..2204)
                     /gene="pta"
                     /locus_tag="IXR40_002528"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HAQ4362324.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(2357..3037)
                     /locus_tag="IXR40_002529"
     CDS             complement(2357..3037)
                     /locus_tag="IXR40_002529"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HAQ4362325.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            3163..4032
                     /locus_tag="IXR40_002530"
     CDS             3163..4032
                     /locus_tag="IXR40_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAQ4362326.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            4058..4573
                     /locus_tag="IXR40_002531"
     CDS             4058..4573
                     /locus_tag="IXR40_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362327.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(4620..5183)
                     /locus_tag="IXR40_002532"
     CDS             complement(4620..5183)
                     /locus_tag="IXR40_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4362328.1"
                     /translation="MIRFARKEDAPEIAPLILVILKDMELPFLKQTGEQKTLEILEEA
                     ITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKYQLDASTRLFI
                     DKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLSVDEKNPKAKK
                     LYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(5238..5417)
                     /locus_tag="IXR40_002533"
     CDS             complement(5238..5417)
                     /locus_tag="IXR40_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362329.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(5494..6003)
                     /locus_tag="IXR40_002534"
     CDS             complement(5494..6003)
                     /locus_tag="IXR40_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362330.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(6099..6479)
                     /locus_tag="IXR40_002535"
     CDS             complement(6099..6479)
                     /locus_tag="IXR40_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HAQ4362331.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            6809..7558
                     /locus_tag="IXR40_002536"
     CDS             6809..7558
                     /locus_tag="IXR40_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HAQ4362332.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
BASE COUNT         2234 a         1616 c         1382 g         2571 t
ORIGIN      
        1 accgtttatt caaaaaaaat ggactgcgac acgacttttg tcacagtccc ttcgtgtgtt
       61 tttctgcctt ctcaaaagga tgacagtttc tcactctttt cctatttctt ctattcaatc
      121 aaataactca ttttatatac atctaaaaat tcacctagat ctgttcttgc ccctctaggc
      181 atgaccgctt cgatttggaa gcccattttt cggtaaaggt gtacggctct ttcattacga
      241 acttgaacgt caagctccaa tcgaaaaagt acacccattt ccttcgccca actgatgatt
      301 tcttctagca taagagtgcc tagtcccatt ccccaatatt cctgcagaat actgataccg
      361 acttctccca cgtgagacaa acgaaattga ctgtctgcct tgacagatgc tgttccaata
      421 atcgtccctt catagattgc aagcagcaat aaattattat tgctttcgta tatataatcc
      481 aactcttctt ctaaggtttc tggtggtaac aggagttctg cttcatccaa aactaaaaat
      541 tctgtctcct tattaacttg tcccatcatc aaaagaatgt cttttgcatc tcctggcact
      601 gcttcccgca agatgatccc aacttcttca ctcatgattt tcagcccatt tttctagaat
      661 tcgctgtttg aaggtttcac tttgctcccc gtatgagatt agtttcacat accgcttttc
      721 taaatctgta tcactttttt ctaaaatcag ttccaaataa tcctccggca gtgcttcttc
      781 taatagattt ccccattcaa caacggaaag cccatcacct tcaaaatatt catctaaccc
      841 taaatctgct ccgctagctg ctacccgata aatatccata tgatacaacg gaatccgacc
      901 ttgactatat tctctaataa tcgtgtatgt cggacttttg atcatttgcg ttatccctaa
      961 tccttgggca attcctttcg tcaacgttgt tttacccgca cctagatcac cagtcaatat
     1021 cagattgtca cctggcattg cggaatgacc aattgcctct gcgaattgtt ctgtcattgt
     1081 taatcctgat agttcgatca tttttcatct tctcccgctc ttctttcttt ttgccagtat
     1141 atcgcgtaat gaagtttttt taaagaaaaa atgaactagt caagaacagc agctgctgtt
     1201 tttggctagt tcgcgtgtat ttgttaatca atcaatgttt gtgctgctgt gataatcgat
     1261 aatttatata catcttcttc atttgctcca cgagacaaat cagaaaccgg tttgttcaag
     1321 ccttgtagaa ttggtccgat tgcttcaaag ttaccgaaac gctgagcaat tttatagccg
     1381 atatttcctg actgcaattc tggaaataca aagactgttg cttgaccagc tacttctgaa
     1441 tctggcgctt tcagttgtgc aactgaagga acataagaag catcaaattg caattcgccg
     1501 tcgatcatgt attgtggcgc tagtttttta gcgattttag ttgcttcaac tactttgtct
     1561 acttctggcg atttcgctga gccttttgtc gagaagctca tcattgctac ttttggttcg
     1621 atatcgaaca attctgctgt ttttgcagaa tctacggcga tttcagccaa ttcttgcgca
     1681 gttggattca cgttgatcgc acaatccgaa aagacatatt tttcttgatc tcttccacgt
     1741 accatgatca tcgctccgct tgtccgactg atgccaggct ttgttttgat gatctgaagt
     1801 gctgggcgaa cagtgtcgcc agtcgaatgg atcgctccag agaccattcc gtctgcaatc
     1861 cccatatacg taagcatcgt accaaagtaa ttcacatctt ttaaaatctt ttctgcttgt
     1921 tctttggatg cctttccatt tctacgttca acaaaagtat ccaccatttc atcccactta
     1981 tcgtaattat cagggctgat gatcgtaaag ctagatgttt tgattcctct ggcatgcgct
     2041 gcatttctta tttcttcttc gttccctact aaaatgggtt ccacaagttc ttctgctttc
     2101 aaccgggcag ctgcgcctaa aatacgagca tcagtagctt ccgggaaaac gattttgatc
     2161 ccacggcgaa caattttaaa tcttaaacta tcaaacaatt ccacaagatg acctccagac
     2221 gtttttatat gtattatcat acactattcc agaaaaaaag aacagtttat tttatctgta
     2281 tcagtcaaaa atgctggaaa aattaagttt ttcacataca aagcgaactg cactataaca
     2341 ggaaagcgct gttttattac actgtttcag gcagttgcca atcaatcggt tcttctccta
     2401 acgcaaggag cgcatcattc gttttcgaga agggtttgga accaaaaaag ccacgacttg
     2461 cagataacgg actgggatgt ggagatgtta tgatgatatg gcgactctta tcgatcattt
     2521 tgattttttc ttgtgccggt tttccccaca agataaacac gattggtttt tcccgttcat
     2581 ttaatttttc aatgatcgtg tctgttaatc tttcccaacc tttcccgcga tgagaatacg
     2641 cttgcccttc ccgaacggta agaacggtgt tgagtaaaag gactccctgt ttagcccatg
     2701 acactagatt tccatgttga acaggtgcga ttccaagatc atcataaagc tctttataga
     2761 tatttcttaa cgatggcggg atctttacgc caggttgcac agaaaaagat aagccatgag
     2821 cttgattttc tccatgataa ggatcttgtc ctaaaatcac cactttaact tcttcataag
     2881 gagtcaattc caatgcttca tagatatgat acatatctgg atggatcttt tgggacgcat
     2941 attctttttt taaaaattct cttagatgca gataataatc ttttgaaaat tctgaggaca
     3001 aaacttcttg ccaactgtta tgaatgattt ctttcaaaaa ctccacctcc taataaaaag
     3061 aataactcac attttcttca atcacaaggg acaatcttca ccctcagcac ttgattaata
     3121 tggtaaacta ggaacaagaa gcagaaagga acgataatca ttatgatcaa attaattgca
     3181 tcagatatgg acggcacatt attagatgcc catatgagtg tttctcctga aaatgccgag
     3241 gcgatacgtt ttgcaaatga tgccggtgtt gagttcatgg tcgctactgg tcgaaactat
     3301 caagaagctc gcgcagcttt agatgaggta ggaatcgatt gtgcgatgat cactttgaac
     3361 ggggcacagg tatttgataa agaaggaaat tcattgttta ccgtgtcgat tccaaataat
     3421 caagcaatct ctgttttaga tattctagat gctaacggta tttactatga agtagcaacc
     3481 aacgatggtc tttattctga aaatcaagcg aaacgaattg aaagttttgc ttccatggtg
     3541 gctacccatt tacctcacct tacgtataaa atggcgattg ccatggcctc agctaagctg
     3601 gagttattgc acatcacata cgtggacagt attcgtgcta ttttggaaga aaagaatctg
     3661 gaagttttaa aaattatttg ttttcataca gaagggccag ctgtattagg tccagttgga
     3721 aagcagattt ctcttttagg cgatctagcc gttacttcct ctggtcaaaa caatatcgaa
     3781 gtgaaccata aaaacgctca aaaaggaatt gctgttgccc atgtcgctca cgagcgtggg
     3841 atttctttag aagaagtcat gacgattggc gataacttca atgatgtcag catgctgcaa
     3901 gtagcaggag tcagtttcgc aatgggaaat gcagaaatcg aagtaaaaga ttatgccaaa
     3961 tatacaacgg acacaaacct tgaatctggc gtaggaaaag ccatattgcg cgcgattgca
     4021 gaagacttgt agttttatct agaaaagagg gatatagatg tcagaatttt tcattcagga
     4081 aaagcagctt ggacgtgcaa ctcggacaat tgtcaaaaac gaaaaaggac attccctgtt
     4141 tttgatggtt ggtcgctggg gaacaaaggg cgatgcattg tctctttatg ccatgaatgg
     4201 cgatctcgtt gctcacatca agcagataag cctgacattc ggtacgcgtt ttgagctgta
     4261 taaagagttc gaaaaggtgg gaaccatgca gaaaatattc aattggcccg gtgactttta
     4321 ttatattcgt agacttcact ggacagtcca aggtgatatc tataatcatc aatatcaaat
     4381 ccatcatttc aatcagcaaa tcatgaaaat ggataaagca acactttttt caggagatta
     4441 ctatgtattg gatgtctcaa atgatgaaga tgctccagtt tgtatttgta ttgctgcggt
     4501 tttagattac tggctctacc gtaaagacaa aagtcgcgat aagcctgttt cttaccgact
     4561 taacttaagt taaaaagatg tacctgaaat gcggaaatac gcatttcagg tacatctttt
     4621 tagatattct tttgcatatg atcataaaga tgaccactga tcatccgctg accgacaact
     4681 ttgaagtcat ggcgttcgta taatttttta gcctttggat ttttttcatc cacacttaga
     4741 ccgatgacgg agcgattagc tttcttcgcc aatttaggta atgcttctaa taatcgcgaa
     4801 ccgatgcctt gtcctctaaa atcttctgat acactgatag agtccaaata ccattcgttg
     4861 ggaaacgttt ctttatcaat gaacaaacgt gtagacgcat ctagctgata tttctctaag
     4921 ataggtacca gtggctgatc gatgattgat tcttcttcat ctgtataacc gtaagcaact
     4981 cctgcaactt taccgtctat ttcttctacg atacctcgtg aataactgta acgataattt
     5041 ggatcagtga ttgcttcttc taaaatctct aaagtctttt gttcccctgt ctgcttcaaa
     5101 aatggcagtt ccatatcttt tagaatcact aagatcaatg gggcgatttc tggagcatct
     5161 tcttttctcg caaaacgaat catagtttcc tctccttttc tccattctaa catgcagaaa
     5221 aagaaatcgc aaaatcgtta ttttaaaaaa tcttcaatct tttcagtaat gaaataacca
     5281 tgagtaacga ttcttgccgc ttcagttcgg caataagggc agacgactgg catttcttta
     5341 tcattatgtt cgactacatt attgacttct tcgtatgcaa atttttttcc gcaattaggg
     5401 catttcattt tttccatgtt atctcaactt cctttcatct ttactctctt agcttactct
     5461 tatattgtaa aaaagagaag caatatcctt cttctatgca gatatccata cctgacggtc
     5521 ctgttctcca tctattaatc ggactttata ataaggacgt tcatctttga ctagaagtgt
     5581 ccactctttc acttttgctt ttttcccgta gtagctgact gcttccttca tcgctgcttg
     5641 cggttgtttg aactcttccg ttttttctat atcaaaaaga tgttctgcgg ccttttccgt
     5701 gtcatttcgt acggttgttt tcccagtgga tggattgact gctatgactt gtccttcaca
     5761 aaaaaactgg tattcatatg ttgcattcgt aggattctcc aaatcttttt caactgcaaa
     5821 atgaatagca gatatgttat gttcttttgt ttcgtttttt acgattgctg ctgctttttt
     5881 caatgagatc cgatattcct ggtcactaat atcatccatg tgaaaagcgg cattgagcag
     5941 tcccgtcata ccggtaatcc ctattacgat gagggcagca acaccaaaca tcattttttt
     6001 cattcttcat tctcctgttt ctttttttta aagaatatca agaaatgaac gaatgaaaaa
     6061 tcgaatgaaa cgaaaaaaaa gtgacaattt tgttatcttt attcgtgcag ttctaatggc
     6121 aatccgtctg gatcaaagaa aaacgtcatt ttttttcctg taaaggtatc ttctctaatc
     6181 ggttctgatt cgatccctaa ggactgcaat tctgcaattg tttcttcaat atcgtctact
     6241 ttgaaagcaa gatgacgcaa gccacaagct tctggatagt ttggtcgttg tggcgcatta
     6301 gcaattccaa aaatctccaa ttcagcactt cctagtttca gatctaattt atagtcatct
     6361 cgttctttgc ggtaattttc tctgattact tcaaatccta atttattaac ataaaaatca
     6421 cgtgatttct gataatctga aacaatgatg gctatatgat ggatcgttgt aaggttcata
     6481 tgagcactcc tattcttcgt ttaagctcgg atctatatta atctccagtt ccattgtaaa
     6541 tgtgtcagat tgaaaaaaat agctgttttt cctttttata aaaaaaaagg caaaaaaaac
     6601 agaaagtagg tcctccaaga cactcttcct gttcccaata taataaatga aagtaagaaa
     6661 ttatattttc aagaaaacaa acagaaaatt atcataacac aaattattta taattgaaag
     6721 actagttttt tttcaagaaa agcatacaat agattgtgtt agtaaataca gaacacacta
     6781 catttagtgt cttaaggagt cctcatacat gaagtcatat tttcagtttt tagctcatca
     6841 gctaaaaggc tggccgcaac aaaattatta tcttttcttt ttcagtcttg gctgccaggt
     6901 catgactctt gtcaatagtc ccatcacttg gctgtccgtt attacattta tcggtaccac
     6961 gcttggtgta ttgtgtattt tatccatcaa tgcggcaaaa tcagtcaacg gtattttagg
     7021 tattttgtct gcgatttgtt ttattatcgt tgggttttca gcaaagaact atttaagtat
     7081 cggtgaacag attgcttata tgatcacatt ggatatcccc gtattgttaa gtaaagaatg
     7141 gaatcataat atggcttcaa aaatccgaaa attcactgga aaaagctggt ttatcgcaat
     7201 catcagtact ttccttgtct atcttgtttc aggattcctg attggtcgtt atacagatga
     7261 tcctcggccg tgggtagatg ccattgcttt ttctattagc ttgactgctg gtatcatcag
     7321 tttcttgcgt tacaacaacc aatattactg gtggttagct tcagggcttg ctcaaatggt
     7381 cctttggtat atttcattta cgcatggatc tgcaagtttg gcgatgttcg tgaacagctc
     7441 tgtttacttg ctgaatgatg tccttgcatt taccgtttca ccttggtata accaaaaaga
     7501 acgtgaacgt atgcaaaaaa tggaagaaga atactacaac gcacaacaac acgcataaaa
     7561 aaactgagcg tgggacaaaa gtaaagaaca cttttgtctc acgctctaaa cacgtataaa
     7621 cggcggaatc agaagcaact ccttcggaaa taagctgaaa ttcacaaaaa tttgaaaagc
     7681 aattttcgtg aatttcttct tatttcttgg agttaaacgc ttctgtccca gcctctattt
     7741 cctacgatta gtcaagtaaa aggtgcaaga aaaatagctc gtaaacgaaa gcgacaaaat
     7801 caa
//
LOCUS       DACGEU010000114         7527 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.117, whole genome shotgun sequence.
ACCESSION   DACGEU010000114 DACGEU010000000
VERSION     DACGEU010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7527)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7527)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7527
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.117"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            32..160
                     /locus_tag="IXR40_002537"
                     /pseudo
     CDS             32..160
                     /locus_tag="IXR40_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
     gene            274..513
                     /locus_tag="IXR40_002538"
     CDS             274..513
                     /locus_tag="IXR40_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362333.1"
                     /translation="MARPVLEAMDMDTLTKGRYVQLLARGYSPKDVFKSLSKGTDMEK
                     ERLRKEFDYWRTHNGIKDLKPARPVIKRKKKITQD"
     gene            625..819
                     /locus_tag="IXR40_002539"
     CDS             625..819
                     /locus_tag="IXR40_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362334.1"
                     /translation="MEEKLLKTMKQKHLKRLSVMQYINDMQITGKEKACLLGSMKNFE
                     QLRRTYVKTSSNCQLLLEVS"
     gene            905..1576
                     /locus_tag="IXR40_002540"
     CDS             905..1576
                     /locus_tag="IXR40_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HAQ4362335.1"
                     /translation="MRKWLFGFLGVALIVFCSVFGYVSYQKHEGEVFKQNIEKKMPVD
                     QINAHAKSYKEDATNVNNDMSLGQMLSIQQEAIEMGVNKQVFAQIQIPALGLALPIFK
                     GANQYTLSLGAATYFYEDAEMGKGNYVLAGHNMEMPGVLFSDIQKLSLGEVMDLVSND
                     GVYRYKVTRKFIVPEYFKLIDGVPEENSFLSLPKKGEKPLLTLFTCVYTSQGKERYVV
                     QGELQ"
     gene            1629..3605
                     /locus_tag="IXR40_002541"
     CDS             1629..3605
                     /locus_tag="IXR40_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HAQ4362336.1"
                     /translation="MAINRYVKKAGMLIGMLGIIAGCFQGYRAYAEDVTQKTPPEKVN
                     ITVHKLMYDQGTQLNVDIDGIKNDGYTHDQYPTGVTKYNKADYGDVEFTLGNITDQVL
                     PREDSDLTNAKVDEIVQDVEDKGSNSEYVKNATNKITSAVDENGEITFTDQPAYVNSK
                     GNVYVVYESKSAAGLVTQKAKPMVVIAPMTDKTGSGFLKNIHLYPKNIVSKLSFELTK
                     FGDDGADQSKQTLLKGAKFELYKGEPGKGTKLGDLVSDDQGKLTATDLTLGKYYFVEV
                     PSEVVVGSDQEPTADQYLLGADARNDAHNKLTFEITNDGVTSDLKASYVNYKAPVIDK
                     TVTNGTGQEHSFQIGDAVNYQGTIHIPTDIAGGADGITVNGVKSETSPYSVFKWGDTA
                     GQGLSYVAAKANIKVTNKDGSVVLKENTDYKIQNSENGFVIDFIVNNGQVSDTVASLH
                     GQDLQMTYNMYVNDSAAVANPLTNSVDFVYNNNPFNQEEHHEKTKADVVTYGAKFLKV
                     DSGLFGTGIKATPLEGAEFAAKNAEGKYYGGLVDTDKDGVKEAVWVDDVANAAILKSD
                     KEGHFEITGLTEGEYSLEETKAPENYQKLTKEISFKVDKDSYKEENRITIKNNQKASV
                     PMTGSNGFQTYVLISCLLLGAGALSAVVYFKKKA"
     gene            3620..4372
                     /locus_tag="IXR40_002542"
     CDS             3620..4372
                     /locus_tag="IXR40_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAQ4362337.1"
                     /translation="MIIRKPKKKRIMGKWIIAFWLLSAVGVLLLMPAEASVAKYQQNQ
                     QIAAIDRTGTAAETDSSLDVAKIELGDPVGILTILSISLKLPIYDGTSDKILENGVGI
                     TEGTGDITGGNGKNPLIAGHSGLYKDNLFDDLPSVKKGEKFYIKVDGEQHAYQIDRIE
                     EVQKDELQRNFVTYLESNPNEDRVTLMTCTPKGINTHRFLVYGKRVTFTKSELKDEEN
                     KKQKLSWKWLLGSTVFLSVMIIGSLFVYKKKK"
     gene            4388..5143
                     /locus_tag="IXR40_002543"
     CDS             4388..5143
                     /locus_tag="IXR40_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362338.1"
                     /translation="MRNRKWLFVCAAALFSFTAYTQLTFADRQESTDSTEQTIQTSDS
                     STIQSSDETVDSSTVDSSEEPKIAEDDQIVKQTIHVQKIISSEQLDNQGHEKQEGVNG
                     AKFSVYDVSDILQKMDVKDLTTDQIESQLKNRVKKLSSDQLKLVSNEETKTIDQQTGV
                     FEFSVEVQANQKQAYYIVNESSPENISNSEDILLLTPVSDKNGEFLKDVWIYPKSEAS
                     QPKEEVKKIVSTGVKKNFFENCWDFVTHLFSRD"
     gene            5156..5416
                     /locus_tag="IXR40_002544"
     CDS             5156..5416
                     /locus_tag="IXR40_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362339.1"
                     /translation="MKLIKLLLFNFSCLTAVFLYCGLLFSKLSILPSYQLYLMRILNI
                     PAASMPLDIMEKLIRNPLFTTINLIVIVGISLVIYKKEGMKG"
     gene            5413..7503
                     /locus_tag="IXR40_002545"
     CDS             5413..7503
                     /locus_tag="IXR40_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HAQ4362340.1"
                     /translation="MNFKHSWTRRLKYVFPIMMMLGTLFGLKTANVFAEKVIVDPSNP
                     IQNVKNNFIIPKDVPNAKTNITVNGASKVYKYHVDANKGGFTDDYVGLVEGNKNIRYP
                     SFQKEYGETNLVLEGVTTNTKVNIDYGKIGTYNGKKVNIKLVLSNIHLYSDTLPWNLL
                     DNNYTKTHFRDDGYKNTNGAMSKSKKRTVLWISDNLFSGIVYHSTQMNVQLVATYEDG
                     SPVQFSGDTFISFNSLNPAGGKSTDLKGEYAHYDKMNTTDWYVRKDTVLSEFKSFYNN
                     LNVVGGHPGGSSKLTQADNDFNNLHDKLGDPKFGQGTVSFKISEANPTFVIGSSNVQT
                     WFTLSSATIFSVVPDQPEKTGVDKNGNNVNDKMLQVGDTIQYRIKQKVNRLGVDLLAV
                     YDRFELIDNLPKEVNYVDAHVESGTNKKFDVSGEVTYDKTKHQVKYAAKADTLKNRMK
                     YNGETYELVINVKVNELANQNSVAKNQGTSIINKVEKDTNIITVYFPKIPVKEVQQNG
                     KDVNGRNDGKKGTPTAPLNAGSEVQYLVTQKWHTKGVDAASDHYKQFSIQDPIEARLT
                     YKEGSAQVIDKSKGKDITSEGTLTYDSNSRTLKWEASADFLSNNLLDGREIQLIFTAK
                     TPLQSEKNIDNQAVVAVDNVSNKTNVVTIGVDPNLPQVIVPKTGSTHLVTISAVSLLL
                     LVLATFSYAVLRYI"
BASE COUNT         2774 a         1173 c         1547 g         2033 t
ORIGIN      
        1 cgtaagaaac cgttaggttt agctaagtgg tgagtagttc acaatgacgc ttacgaatga
       61 taatggagac gaattatctg ttgaagatac ttggtcatat ttgagtgatt atattgtcag
      121 cgttgaaatc attgaatttg tagcggataa agaagaataa aaactggagg aataaatttt
      181 acagataaag gcttagaaga agtcacgacg aataataaaa aggtagtatt accttaggca
      241 ttgagtaagg aattcattta ggaggaaaat tagatggcgc gaccagtttt agaggcgatg
      301 gatatggata ctttgacaaa aggaaggtat gtacagctgt tagctcgtgg ttattcacct
      361 aaagatgtat tcaaatccct gtctaaagga acagatatgg aaaaagaaag attacgaaaa
      421 gaattcgatt attggagaac ccataatgga atcaaggatt tgaaaccagc acggccagta
      481 attaaacgaa agaaaaagat aacccaagac tgaagtgtag agcgtatgtg atcataggct
      541 tttttatttt tgcaaaaaac aaggaaggta ggaaaactca tgaattatga agaaatcgaa
      601 aacagaaaaa aagtgtcgaa ataaatggaa gaaaagttgc taaaaacgat gaaacaaaaa
      661 caccttaaaa gattatctgt catgcaatat atcaatgata tgcagataac aggaaaagag
      721 aaagcttgtt tgttaggttc aatgaaaaac tttgaacagt tgagacgaac ttatgtgaaa
      781 acaagttcta attgtcaact attgttagaa gtctcatgac attcattaat agaattcatt
      841 tttaaaactt tttctatgga aatgagaaaa agattttttg ttttgtctga aagggggtag
      901 ctggatgaga aaatggttat ttggtttttt aggagtcgct ttaatcgtct tttgcagtgt
      961 gtttggctat gttagctacc aaaaacatga aggagaggtg tttaagcaaa atatagaaaa
     1021 aaagatgccc gtagatcaaa tcaatgcaca tgcaaagagt tataaggagg atgcaacgaa
     1081 cgtcaataat gatatgtctt tggggcaaat gttgtccata caacaagaag caatcgaaat
     1141 gggcgtcaat aaacaagtat ttgcacaaat tcagattcct gcacttggtt tagcattgcc
     1201 aatttttaaa ggggcaaatc aatacacttt gagtcttgga gcggctactt atttttatga
     1261 agatgctgaa atgggcaaag gaaactatgt cctagcaggt cataacatgg aaatgccagg
     1321 tgttttattt tctgatattc aaaagttgtc attaggggag gtgatggact tagttagtaa
     1381 cgatggcgtc tatcgttaca aggtaacgcg taaatttatc gtacctgagt actttaaatt
     1441 aatcgatggc gttcctgaag agaactcttt cttgtctttg ccaaagaaag gagagaaacc
     1501 cttattaacg ttgtttactt gtgtttatac gtcacaagga aaagaaagat acgtggtaca
     1561 gggagaacta caataacaag gttttaatca acgtgagtcg ttgaaatatg aaatgaggag
     1621 agtaaaaaat ggcaataaat cggtatgtaa aaaaagctgg aatgcttatt ggaatgttag
     1681 gaatcattgc aggctgcttt cagggatatc gagcatatgc agaagatgtc acgcaaaaaa
     1741 cgccaccaga gaaggtcaat atcacggttc ataaattaat gtacgatcaa ggaacgcaat
     1801 tgaatgttga tattgacggg atcaaaaacg atggttatac gcacgatcaa tatcctacag
     1861 gtgtaacgaa atacaacaag gcagattatg gtgatgttga gtttacgtta ggaaatatta
     1921 cggatcaagt attaccgaga gaagattctg atctaaccaa cgcgaaagtg gacgagattg
     1981 tacaagatgt agaagacaag ggatctaaca gtgagtacgt caagaatgca accaacaaaa
     2041 ttacttcagc tgtagatgaa aatggtgaga tcacttttac tgatcaacca gcctatgtca
     2101 attccaaagg gaatgtatat gtggtttatg aaagtaaatc cgctgctgga ttagtcacac
     2161 aaaaagcaaa accaatggtt gtgattgcgc caatgacaga taaaacagga tcaggatttt
     2221 taaaaaatat tcatttgtat cctaagaaca ttgtttctaa gttgagtttt gaattaacga
     2281 aatttggtga cgatggcgca gaccaaagca aacaaaccct tttaaaaggg gcaaaatttg
     2341 agttatacaa gggcgaacct ggaaaaggaa caaaattggg tgatcttgta tcggatgatc
     2401 aaggaaagct gactgcgact gatttgacgt taggaaaata ctattttgtg gaagttcctt
     2461 cggaagttgt agtgggatca gatcaagaac caacagcaga tcaatattta ttaggcgcag
     2521 acgctcgcaa cgatgcgcac aataaattaa cctttgaaat tacgaatgat ggcgtgacaa
     2581 gtgacttaaa agcttcatac gtaaactata aagcaccagt gatcgataaa acagtaacaa
     2641 atggaacagg acaagaacat tctttccaaa ttggtgacgc agtaaattat caaggaacga
     2701 ttcatattcc aacagacatt gcaggtggcg cagacggtat cacagtaaac ggtgtgaaaa
     2761 gtgaaacttc tccttacagt gtatttaaat ggggagatac agcaggacag ggactttctt
     2821 atgtcgctgc taaagcaaat atcaaagtaa caaataaaga tggatctgtg gtattaaaag
     2881 aaaatacaga ttataaaatc caaaattcag aaaatggctt tgtgatcgat tttatcgtga
     2941 ataatggcca agtaagtgat actgtagcaa gtttacacgg acaagatctt caaatgactt
     3001 ataacatgta tgtaaatgac agcgcagctg ttgccaatcc attaacaaat agcgtggatt
     3061 tcgtttataa caacaatcca tttaatcagg aagaacacca cgaaaaaacg aaagctgacg
     3121 ttgtgactta tggtgcaaaa ttcttaaaag tcgatagcgg actatttgga acaggaatca
     3181 aagcaacacc gcttgaaggc gcagaatttg ctgctaaaaa cgcagaagga aaatattatg
     3241 gtggattagt tgatacggat aaagacggtg tcaaagaagc agtatgggta gacgatgtag
     3301 caaatgcagc gatcctaaaa tcagataaag aaggtcactt tgaaatcact ggtttaactg
     3361 aaggtgaata ttcactggaa gaaacaaaag cgcctgaaaa ctatcaaaaa ttaacgaaag
     3421 agatctcttt caaagtagac aaagattcat acaaagaaga aaaccgaatc acgatcaaaa
     3481 acaatcaaaa agcttccgta ccaatgaccg gtagcaacgg ttttcaaacg tatgtattaa
     3541 tctcttgctt gttgctagga gcaggggcac tttctgcagt tgtttacttt aagaagaaag
     3601 cctagaagga tcaaaaccaa tgattatcag gaagcctaag aaaaagcgaa tcatgggtaa
     3661 atggatcatt gctttctggt tactttcagc tgtaggtgtc ttacttttga tgcctgctga
     3721 agcgagcgtg gcgaaatacc aacaaaatca gcagattgcc gcaatcgatc gaacaggaac
     3781 ggcagcagaa acggattctt ctttggatgt tgctaagatt gagttaggcg atcctgttgg
     3841 tattcttaca attctaagta tttctttaaa actaccaatt tatgacggaa cgtccgacaa
     3901 aattttagaa aatggtgtag gtattacgga aggaactggt gatattacag gaggaaacgg
     3961 taaaaatcct ttaatcgcag gtcatagtgg actttataaa gataatcttt ttgatgattt
     4021 accttcagta aaaaagggag aaaagtttta tatcaaagtt gatggtgagc agcacgctta
     4081 tcaaatcgat cggattgagg aagtgcaaaa agacgaacta caaagaaact ttgtcactta
     4141 cttagaatca aatcccaatg aagatcgagt aacgctaatg acatgtacgc ctaaggggat
     4201 caacacacac cgttttctag tgtatgggaa gcgagtaacc tttacaaaat cagaattaaa
     4261 agatgaagaa aataagaaac aaaaattatc ttggaaatgg cttttaggaa gtactgtttt
     4321 tctttcagtc atgatcattg gttcgctatt tgtttataaa aagaaaaaat aaaggagggt
     4381 aaccaacatg agaaatagaa aatggctatt tgtttgtgca gccgctcttt tttctttcac
     4441 tgcctacaca cagttgacgt ttgcagacag acaagaaagc acggatagca cagaacaaac
     4501 aatccaaacg tcagatagca gcacgattca aagcagcgat gaaaccgtcg attcgtcaac
     4561 agttgattct tcagaagaac ctaaaattgc tgaagacgat caaatagtca aacagaccat
     4621 tcacgttcaa aagattattt cttcagaaca attagacaac caggggcatg aaaaacaaga
     4681 aggagtaaat ggcgcgaagt tttctgttta tgatgtatcg gacattttac aaaagatgga
     4741 tgttaaggat ctcactactg accaaattga atcccaatta aaaaatcgag tgaaaaaact
     4801 atccagtgat caattgaagc tagtttctaa tgaagaaaca aagacaattg atcaacaaac
     4861 aggtgtcttt gaattctcgg tagaagtaca ggcaaatcag aaacaagctt attatattgt
     4921 caatgaatca agtcctgaaa acatttctaa tagcgaggat attttgctat taacacctgt
     4981 ttctgataaa aacggtgaat tcttaaagga tgtgtggatc tatcctaaat cagaagcttc
     5041 gcaacctaaa gaagaagtaa aaaaaatcgt ttctactggc gtaaagaaaa acttctttga
     5101 gaattgttgg gattttgtta ctcacttgtt ttctagagat taaggaagaa ataaaatgaa
     5161 actgatcaaa ttattattat tcaatttttc ttgtttaacc gcagtctttt tgtactgcgg
     5221 tttattattt tctaaactat ctattttgcc aagctaccaa ctatacctaa tgaggatttt
     5281 aaacatacca gctgcttcca tgccgctaga tattatggaa aagctcatta ggaatccatt
     5341 atttactacg atcaatttga tcgttattgt cggaatttca ctagtcattt ataaaaaaga
     5401 ggggatgaag ggatgaattt taaacactcg tggacaagac ggttaaaata tgtttttccc
     5461 ataatgatga tgttaggtac attgtttggg ttaaaaacag ccaatgtctt tgctgaaaaa
     5521 gttattgtcg atccgtcaaa tccaatccag aacgtaaaga ataattttat tattccaaaa
     5581 gatgttccta atgcaaaaac aaatattact gtaaacggag cgtcaaaagt ttacaaatat
     5641 catgttgatg ccaacaaagg tggttttaca gacgactacg taggattagt ggagggaaac
     5701 aaaaatatac gctatccttc tttccaaaaa gaatacggtg aaacaaacct tgttttagaa
     5761 ggcgtaacaa ccaacaccaa agtcaatatt gactatggaa aaatcggtac gtataacggg
     5821 aaaaaagtca atatcaagct agttctatct aatattcact tatactcgga tacgttgccg
     5881 tggaatctac tagataacaa ctatacaaaa actcattttc gagacgatgg ctataaaaat
     5941 acgaatggtg caatgagtaa atctaaaaaa agaacagtac tttggatctc agacaatctt
     6001 ttctcaggaa ttgtttacca ttcaacacaa atgaatgtgc agctagtagc cacatatgag
     6061 gacggtagcc ccgttcaatt ttcaggagat acatttatca gttttaactc tttgaaccct
     6121 gcaggaggaa aaagcacgga tcttaaagga gaatatgccc actatgacaa aatgaatacg
     6181 acagattggt atgtcagaaa agatacggtt ctttcagaat ttaaatcttt ctacaacaat
     6241 ctgaacgtgg taggtggcca cccaggagga agctctaagc tgacacaagc ggataatgat
     6301 ttcaataatt tgcatgataa attaggagat ccgaagtttg gtcaaggtac tgtgtccttt
     6361 aaaatatctg aagcaaatcc gacgtttgtg attggttctt ctaatgttca aacctggttt
     6421 actttatctt ctgcgacaat ctttagtgtt gttcctgatc aacctgaaaa aacaggggtt
     6481 gataaaaatg gaaataacgt gaacgataaa atgttgcaag taggagacac gattcaatat
     6541 cgaatcaaac agaaggtgaa tcgattagga gtggatttac tagcggttta cgatcgattt
     6601 gagttaatcg ataatttacc aaaagaagta aattacgtcg atgcacacgt tgaaagtggt
     6661 acaaataaaa aattcgatgt atctggtgaa gtgacctatg acaaaacaaa acaccaggta
     6721 aaatatgcag cgaaagctga tacattaaaa aatcgaatga agtataacgg cgaaacttac
     6781 gaattagtga tcaatgtaaa agtcaatgaa ttggccaatc aaaatagtgt agccaaaaat
     6841 cagggaacgt cgatcattaa taaagtagaa aaggatacaa atatcattac cgtttatttc
     6901 cctaaaattc cagtgaaaga agtacaacaa aatggaaaag atgtaaacgg acgaaatgac
     6961 ggtaagaagg gtacgccgac agctccttta aacgcaggat ctgaagtaca atatctagtc
     7021 acacaaaaat ggcacacaaa aggcgtagac gctgcgtcag atcactacaa acaatttagt
     7081 attcaagatc caattgaagc tcgtttgaca tataaagaag gttctgcgca agtaatagat
     7141 aagagtaaag gaaaagatat tacttctgaa ggcacactaa cctatgatag caattcaaga
     7201 acgctgaagt gggaagcttc cgctgacttc ttaagtaaca atcttttaga tggacgagaa
     7261 attcagctga tatttacagc taaaactcca ttacaatcag aaaaaaatat tgataaccaa
     7321 gccgtagtag cagtagataa tgtttctaat aaaacaaatg ttgtgacaat tggggttgat
     7381 cctaacttgc cacaggtcat tgttcctaaa acaggttcta cacatttagt aacgatttca
     7441 gcggtcagct tactattact tgtgttagca acttttagtt atgcggttct gagatacatt
     7501 taaaataaaa aaacgaaaga atgaata
//
LOCUS       DACGEU010000115         7320 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.118, whole genome shotgun sequence.
ACCESSION   DACGEU010000115 DACGEU010000000
VERSION     DACGEU010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7320)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7320)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7320
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.118"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(369..995)
                     /locus_tag="IXR40_002546"
     CDS             complement(369..995)
                     /locus_tag="IXR40_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362341.1"
                     /translation="MDKAEFTNFYWKYYLHLENEFINTTDFVMLDENNFKTFSIEYQK
                     LLLAIGSECEIIFKELCGFDSSSNKSITDFKAVIKSSELMCLDNGVRVMNSLTLTSLK
                     PFGDGWPEDTPDWWKIYNRVKHGRSSNYKEANLENVLYALASLYLLEEYLHKKVILEG
                     EVDFISPESNLFTLSWERKHSSMQKVTFEKVDSNYVAPLIDFKEQEEI"
     gene            complement(1290..1625)
                     /locus_tag="IXR40_002547"
     CDS             complement(1290..1625)
                     /locus_tag="IXR40_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HAQ4362342.1"
                     /translation="MPIIKNVNELTERVKFKKTKRVKDEDGQMVDSEETVFECWANVR
                     SQMLKDVLASVGTILEGTLTFIIRYDQDYELTNDMKVAWKNKSYKIISINEGTAFKDY
                     TTIIAKQIS"
     gene            complement(1612..1896)
                     /locus_tag="IXR40_002548"
     CDS             complement(1612..1896)
                     /locus_tag="IXR40_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HAQ4362343.1"
                     /translation="MVILDSIKKSMRIDHTIDDDFIQQLIDTAGEYIKSAIDSSATDK
                     DMDNYQQFDLAVSLLTQHWYLNRQEASSERIPVTVQALVQQMRGAYYANH"
     gene            complement(1952..3475)
                     /locus_tag="IXR40_002549"
     CDS             complement(1952..3475)
                     /locus_tag="IXR40_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HAQ4362344.1"
                     /translation="MNNEEEKEKRLTEEAELTADSPKVEKENEKQPTDGKTISGYALK
                     FGQPSKDLGGFVEVITPEALKEVDLSNVFLLYGHDYSKPLASVKAGTLKLNVDDTGLH
                     FEAELTDTTYSNDVYENISKGVVDSMSFGFVLGLDSFDKKEDGTIERSIDKIKALNEI
                     SVVTVPAYDSSNVQVNKRSYESFMSNNQAKQTNNSLESTSKAQKESNNMEKTLIDNEK
                     TELRGYEEYIRSQGEVRDGVTTVNAAAVVPEEVIGEVFDLKRSNYNLAQYATVKTVSN
                     GQGKYPVATNQQAVLATKAELAEIGDIDAEMFTSVDYKVETRAGKIALSNEVVEDSAV
                     NIVQEVKDQLAKLVENTDNKHIMDLLKTFTKKTAATLDDLKQLYNVALDPALNKMVIL
                     NQSGYYHLDTLKDSDGRYILQPDVTAPSGKSLFGMPVVLIADTLFANPKAGTFPMIMG
                     DIAQSIFVARRNQVTTQWEKFDYYSQGLAVIVRNDYKKIDQNASVYIEFTPVVTPKV"
     gene            complement(3468..4643)
                     /locus_tag="IXR40_002550"
     CDS             complement(3468..4643)
                     /locus_tag="IXR40_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HAQ4362345.1"
                     /translation="MAFFKARQNTTGDPFLQHVVSIQSDDYTTSFTSVRALRNSDVFA
                     AVRIIASDIASSPIQLVKNNMPQADNELVKLLNEKPNSEMDGWHLKFALAVNMLLNGN
                     SFAEIKRNGEKVEEIHLLPNSSVTVTQLDNGTLSYQIGDKKRRVKSSDILHFKYFTQD
                     GLTGLPPLYALRDELKIQQAGNRTLHNFFTRGVSGSGILKVHKSDLDGSAKNAIREKF
                     EEANGSSSGDNALRTIILDETMDYKTLEINTDVLKLINSNDWNTKQIAKAFGVPIERL
                     GVENEHSSTVQSNLQYIQSTLIHYFNVFVSELDTKLETNIRFNSDQLLETDPETKVKN
                     VLDQVKGSLLTINEGRSKMGLPPMDGGDRLLASLNFTYLDTLEKYQLKEQEGVTPVE"
     gene            complement(4647..4832)
                     /locus_tag="IXR40_002551"
     CDS             complement(4647..4832)
                     /locus_tag="IXR40_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362346.1"
                     /translation="MNFIQVKNFLSNYIHTVLLLLGLVCVLVAITLLTNVYYGLLALG
                     IVLIGVAVMLNTEQKGG"
     gene            complement(4798..6492)
                     /locus_tag="IXR40_002552"
     CDS             complement(4798..6492)
                     /locus_tag="IXR40_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HAQ4362347.1"
                     /translation="MNDYIEKVLSGKLIAPKKIIQACERHISDLERSKSDSFPYVFDE
                     EQATKAIKFIELLPSTDGKAIKMLGFQKFILGSLYGWRTKEGNYRRFNRAFTSMSRKN
                     GKTYIASGMAANALIMEQEPAEARQVLFVSNALKQAKLGYDMLSNSLRNVVKSSKFLR
                     PQLKIMNSKIQHLPSNSFAMALASETSTLDGFAPTTAILDEWHEAKTRKTYNVIKSGM
                     TQQKNGLLCVISTAGLDLNVPMYEEYLLLDRVLKGEEQADRYFIAIWELDDPEEIHDQ
                     EKWIKANPIFESEEIKKVMIPTIQDDVNLALKQNNLNSVLVKNFNLWRQASEDSYMIA
                     EDWQATEVEPQDITGKPVYIGVDLSKTDDLTSVSWIVPLDNGELYCDSHSFVATKYGL
                     QDKEKRDGLPYRELEKAGECSITQLESGIVDYDQVFQFIQDLIQENDLECMGICYDPY
                     NANSLISKAEKANYPMLEVRQGTITLNVPTRTFREQVYEGNVIHNKNTILTHAVNNAI
                     LKTDNNGIQINKSKNSNKIDPIAALINAYVFAMDYFTTTEGAKADNEFYTSEEFSF"
     gene            complement(6489..6962)
                     /locus_tag="IXR40_002553"
     CDS             complement(6489..6962)
                     /locus_tag="IXR40_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HAQ4362348.1"
                     /translation="MGHPKILHDTKGNISSEEKAIRVDAREELFKQQPLINITPPDWM
                     AASARSEWNRIVPTLKKDYPLSEADYGSLVAYCLAFARMKTAEAEIRKSGTFITCENG
                     VKKANPAVRVQSQAMSDLKKQATSLGMTLESRSKLALNKVKNDEPEDPFKELMNS"
     gene            complement(7031..7186)
                     /locus_tag="IXR40_002554"
     CDS             complement(7031..7186)
                     /locus_tag="IXR40_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2292 domain-containing protein"
                     /protein_id="HAQ4362349.1"
                     /translation="MKVGDLLKNTIVITDKTGKQRTIELPHFGQVTIQMQNGKIIYID
                     KLDKEKF"
BASE COUNT         2035 a         1527 c         1178 g         2580 t
ORIGIN      
        1 ggaagagact gtgaagtcaa cgttttgacc tgattattag agaaacaaat ggcaaaatag
       61 ttcttcatat ttcgccgttt ttcgagcgaa tgccgagggg cagctgattg aacatcgttt
      121 atttggaaaa agggattgtg acaagacgtt tgtcacaatc ccttttttta tatcttatta
      181 attcattctt ttgttctatt cttcttcttc cgccatgaat gagaaaccca tatcaaagaa
      241 ctataaaggt tatcaaaaca gcgtttatga ctaaatgaat tagagttatc tatcactatt
      301 tttcaagcga tttaaaccaa atggcataca atatggcata caaaaacttc aataagccgt
      361 gggggttttt aaatttcttc ttgttcttta aaatcaatga gtggagctac ataatttgaa
      421 tccacttttt caaacgtcac tttttgcatc gacgaatgtt ttctttccca agataacgta
      481 aatagatttg actctggact tataaagtct acttcacctt ctagtattac tttcttatgc
      541 aaatattcct ctaataaata tagacttgct aaagcataca acacattttc caaatttgct
      601 tccttataat ttgaagaacg accatgtttt actctgttat atattttcca ccaatctggt
      661 gtatcttcag gccacccatc tccaaaaggt tttagtgaag tcaatgttaa agaattcata
      721 accctaacac cattatccaa acacattaat tcgctagatt taataacagc tttaaaatca
      781 gttatgcttt tattgctact gctatcaaat ccgcaaagtt ctttgaaaat aatctcacac
      841 tccgaaccaa tcgctagtag tagtttttga tattcaatag agaatgtttt gaaattattc
      901 tcatcgagca tcacaaaatc tgtggtatta ataaactcat tttctaaatg tagataatac
      961 ttccaataaa aatttgtaaa ctctgctttg tccattaaat cacctctttt gaattataac
     1021 aaaaaaaaca cgtccacaac agacgtgttc tttgatttct acacaatcag cttgccaaaa
     1081 ccatccaatc agtcctagca tgcctgtatt aaaattgaac gttcatcatc tatcatcttt
     1141 cttagtccag catgtttgca accacaccta caattttcag tccaacaata gatttcgact
     1201 agctaagtct tgcaaaattc aggcagctaa cccttcattt actaccttaa ttatactaaa
     1261 tacccacaac gtttacaagt gtaatcattc taagaaatct gtttagctat gatcgttgta
     1321 taatctttaa acgccgttcc ttcattgatt gaaataattt tataactctt gtttttccaa
     1381 gctactttca tatcgtttgt tagttcataa tcttgatcgt atcgaataat aaacgtcaac
     1441 gttccttcaa gaatggtacc tacactagca agcacgtctt ttagcatttg tgaacgcaca
     1501 ttagcccaac attcaaatac agtttcttca ctatccacca tctgcccatc ttcatctttt
     1561 acccgttttg tctttttaaa cttgactctc tcagtcaatt catttacatt cttaatgatt
     1621 ggcataataa gcacctctca tttgttgtac taatgcttgt accgttactg gtatccgttc
     1681 gctgctggct tcttgacggt tcaaatacca atgttgagta agtaatgaca ccgccaaatc
     1741 aaattgctga taattatcca tatctttatc cgttgcgcta ctatcaatag cactttttat
     1801 atattcgcct gctgtatcaa tcaattgttg aataaagtca tcatcaatag tgtgatcgat
     1861 ccgcatactt ttttttatgc tatccaaaat taccatttta tctctcctaa tgaaaaaaag
     1921 gcagtgggat aaaccgccgc ccaatatttt tctatacttt tggtgttaca actggcgtaa
     1981 actcaatata cactgaagca ttttgatcaa ttttcttata atcgttgcga acgatcactg
     2041 caagtccttg tgagtagtaa tcgaattttt cccattgagt cgttacttga tttctacgag
     2101 caacaaagat agattgtgca atatccccca taatcatagg gaatgttcca gctttaggat
     2161 tggcaaacaa tgtatctgca atcaatacta ctggcatacc gaataatgat ttaccactag
     2221 gtgctgtcac atcgggttgt aaaatgtaac gtccatctga atctttcaat gtatctaggt
     2281 ggtaatatcc gctttggttt agaattacca ttttatttaa tgctgggtct aatgccacat
     2341 tgtatagttg tttcaaatcg tccaacgtag cagccgtttt cttagtgaat gtttttaata
     2401 aatccatgat atgcttattg tcagtgtttt ctaccaattt cgctaactga tctttgacct
     2461 cttgtacaat attcactgct gaatcttcca caacctcatt tgataaggca atcttaccag
     2521 cacgagtttc tactttataa tcaactgaag taaacatttc agcgtcaata tcaccaattt
     2581 cagcaagttc agcttttgtt gctaacactg cttgttggtt agttgctact ggatatttac
     2641 cttgtccatt tgatactgtt tttactgttg catattgagc taagttataa tttgaacgtt
     2701 tcaaatcaaa gacttcaccg attacttctt cgggaacaac tgccgctgca tttacagtag
     2761 tgactccatc acgcacttcg ccttgtgaac ggatatattc ttcataccca cgcaattctg
     2821 ttttttcgtt atcgattaaa gttttttcca tgttattact ctccttttgt gctttagaag
     2881 tggattctaa gctattgttt gtttgttttg cttggttgtt actcataaac gattcgtaag
     2941 aacgcttatt tacttggaca tttgatgaat cataagcggg aacggtcacg acactaattt
     3001 cattaagtgc tttgatttta tctattgatc gttcaattgt gccatcttct tttttgtcga
     3061 atgaatctaa tccaagcacg aacccaaagg acatagaatc aacaacccct tttgagatat
     3121 tctcatacac atcatttgaa taggtcgtgt cggttagctc tgcttcaaaa tgtaatcctg
     3181 tatcatcgac attcaatttc aacgtacctg ctttgacact agctagtggc tttgaataat
     3241 cgtgtccata taataagaac acatttgata aatccacctc ttttaatgct tcgggtgtaa
     3301 tcacttctac aaagccgcct aaatcttttg acggttgccc gaatttcaac gcatagcctg
     3361 aaatagtttt gccgtctgtt ggttgttttt cattttcttt ctctactttg ggagaatcgg
     3421 ctgttagctc agcttcttct gtcagccgtt tttccttttc ttcttcatta ttcaactggt
     3481 gtaactcctt cctgttcttt taattgatat ttctccaacg tatctaaata cgtaaagttc
     3541 aaacttgcta gtaaacgatc gccaccatcc atggggggta gccccatttt cgaccgcccc
     3601 tcattaatcg tgagaagtga ccctttgacc tgatccaata cattttttac ttttgtttca
     3661 ggatcagtct ctagtaactg atcggaatta aagcggatat tggtttcaag tttcgtatct
     3721 aattcactca caaacacatt aaagtaatga atcagcgtac tttggatata ctggagatta
     3781 ctttgaacgg tgctagaatg ttcattttca acgcctaaac gctcaatcgg tacaccaaac
     3841 gccttggcaa tttgttttgt gttccaatca ttggaattga taagcttcaa aacatcggtg
     3901 tttatttcta atgttttgta gtccattgtt tcatcaagaa tgatcgttct aagagcatta
     3961 tctccactac ttgaaccgtt ggcttcttca aacttttcac gaattgcgtt ctttgctgat
     4021 ccgtctaaat ctgacttatg aaccttcaaa atacctgacc cactgacacc acgagtaaag
     4081 aaattgtgca atgtgcggtt gccagcttgt tgaattttca gttcatcacg taacgcataa
     4141 agtggtggta atcctgttaa accatcttgg gtgaaatatt tgaagtgcaa aatatcgcta
     4201 gacttcacac gtcttttttt atcaccaatc tgataagaca acgtaccatt atctaattga
     4261 gtaaccgtta cacttgagtt aggtaataag tgaatttctt ctaccttttc accgttgcgt
     4321 ttaatctctg caaagctatt accgtttagc aacatattga ccgccaaagc aaactttaaa
     4381 tgccaaccat ccatttctga attaggtttc tcgtttagta acttcaccag ttcattatca
     4441 gcttgtggca tattgttttt gaccaattga atcggacttg aagcaatatc actagcaata
     4501 attcgaacgg ctgcaaacac atcactattt cttaatgcac gaacgcttgt aaagctggtg
     4561 gtgtaatcat ccgattggat tgataccaca tgttgtagga aaggatctcc cgttgtattt
     4621 tgtctcgctt taaaaaatgc catcttttaa cctcccttct gttctgtatt tagcatgacc
     4681 gctaccccaa taagcactat gcccagcgct aacaagccat agtagacatt tgttagtaag
     4741 gtgatagcaa ccaacacaca caccaatcca agaagtaaaa gaacggtatg aatgtaatta
     4801 gaaagaaaat tcttcacttg tataaaattc attgtctgct ttcgctcctt ccgttgtggt
     4861 gaagtaatcc attgcaaaca cataggcatt gattaatgca gctattggat caattttgtt
     4921 actgttcttt gatttattaa tctgaatgcc gttgttatcc gtttttaaaa tagcgttgtt
     4981 cactgcatgg gtgagaatcg tatttttatt gtgaataacg ttgccttcat aaacttgttc
     5041 tctaaaagtt cgggtcggaa cgtttagagt aatcgttcct tgtcttactt ctaacattgg
     5101 gtagttggct ttttcagctt tactgataag cgaattagcg ttatacgggt cataacaaat
     5161 ccccatacat tccaaatcat tttcttgaat caaatcttga ataaactgaa atacttggtc
     5221 atagtccacg attccacttt ctaattgagt aatggaacac tcaccagctt tttctagttc
     5281 tcgataaggc aaaccgtcgc gcttttcttt gtcttgaagc ccatatttgg tggctacaaa
     5341 gctatgtgaa tcacaataaa gttcgccgtt atctagcggt acgatccatg aaacgctagt
     5401 taaatcatct gttttagata aatccactcc gatataaacg ggcttgcctg taatatcttg
     5461 tggttctact tcggttgcct gccagtcttc agcaatcata tagctgtcct cactcgcttg
     5521 tctccataaa ttgaagtttt tcaccaatac agaattaagg ttattttgtt tcaaagcaag
     5581 gttcacatca tcttgaatgg ttggaatcat tacttttttg atttcttcac tttcaaaaat
     5641 cggattggct ttgatccatt tctcttgatc gtgaatttct tcgggatcgt ccaattccca
     5701 tatcgctata aagtacctgt cggcttgttc ttcgcctttt agcacacgat ctaacaataa
     5761 gtattcctcg tacataggaa cgtttaaatc aagcccagcg gtactaataa cacacaataa
     5821 gccgttcttt tgttgggtca ttcctgactt aatgacgttg tacgttttac gagtttttgc
     5881 ttcgtgccac tcgtcaagaa ttgcggttgt tggtgcaaac ccatctagcg tgctggtttc
     5941 actagccagt gccatagcga acgaattaga gggcaagtgc tgaatcttag agttcataat
     6001 tttcagttgt ggtcttaaaa acttactaga cttgaccacg tttctaagtg aattagacag
     6061 catatcatag cccaatttag cttgtttcaa agcgttactt acaaacaata cttgccttgc
     6121 ttctgctggt tcttgttcca taatcaacgc attggcagcc atgccacttg cgatatacgt
     6181 tttcccattc ttacggctca tactggtaaa cgctcgattg aatcgcctgt aattcccttc
     6241 tttagtacgc cagccataaa gactgcctag aatgaatttt tgaaatccta acatcttgat
     6301 tgctttaccg tccgtagatg gtagcaactc aatgaattta atcgctttgg tggcttgttc
     6361 ttcatcgaac acataaggga agctatctga cttagaacgc tccaaatcgc ttatatgacg
     6421 ctcacacgct tggataattt tcttgggtgc aatcagctta cctgatagga ctttctcaat
     6481 gtaatcattc atgaattcat caactctttg aacgggtctt cgggttcatc atttttaacc
     6541 ttgttcaaag ctagttttga tcgtgattct aaggtcatac ctagtgaggt ggcttgtttt
     6601 ttcaaatcac tcatagcttg tgattgaacc cgaaccgctg gattggcttt ctttactccg
     6661 ttttcgcatg tgataaacgt acctgatttt cttatctcgg cttcggctgt tttcattcga
     6721 gcaaaggcta aacaataggc taccaatgaa ccataatctg cttcactcaa tggataatct
     6781 ttttttaatg ttggtacgat acgattccat tcacttctag cgctcgctgc catccagtca
     6841 gggggcgtga tatttattaa tggttgctgc ttgaacaatt cttctctagc gtccacacgg
     6901 attgcttttt cttcacttga tatattgcct tttgtatcgt gtaatatttt agggtgtccc
     6961 atgttgtcct cctttcagac aaaagaaaaa ggaacgtaag caattaagct cacattcctt
     7021 cgtttttcga tcagaatttt tctttatcta atttatctat ataaatgatt tttccgttct
     7081 gcatttgaat ggtcacttga ccaaaatgag gtaactcaat ggtgcgctgt ttccctgttt
     7141 tatcagtaat aacaattgta tttttcaata aatctcctac tttcattata tactttttca
     7201 cttgtgatta caagtgtaat cgttatttgt aattaccctt atgccttttc acaacggtta
     7261 tttgtaccaa aatgagtagg catcgattgt cagtaagttt cacactatgc ccccttaact
//
LOCUS       DACGEU010000116         7018 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.119, whole genome shotgun sequence.
ACCESSION   DACGEU010000116 DACGEU010000000
VERSION     DACGEU010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7018)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7018)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7018
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.119"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            <1..640
                     /locus_tag="IXR40_002555"
     CDS             <1..640
                     /locus_tag="IXR40_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362350.1"
                     /translation="KLIFVNNNQKYFSFNTLYGKAKDNYTITDPIVRVINPEITESLF
                     WGNILTSDGGLFFDQKHTSNQNFFNQINPYIKEFNLENIINFSYSVFQETGELLSQKK
                     VNKLNAYLQYLLILGLFIIINFQMIFVSFTINSKKIALKKIFGYSPISQVLDLCLLPF
                     TIELFATMCFQLIFSKNTYLYFIIFMIFLINLITSIIIYKKNSFKYFKENIL"
     gene            637..1257
                     /locus_tag="IXR40_002556"
     CDS             637..1257
                     /locus_tag="IXR40_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4362351.1"
                     /translation="MILSVENFTLSINKKKIKQNWNFSISEKDFIIVTGKSGSGKTTL
                     LNNLSLIDKQYTGNLFYFEKKVSKHDIQRLRRNHISYLFQNYALLENQTVQYNFELAK
                     KFNSNISNDHIYNLLTDFSLPKDILKEKIFLLSGGEQQRIALIRNMLKPFDILFADEP
                     TGNLDKENSTFIMNFLKNLTEKEKKAVVLVTHDLNVLNYGTNIIEL"
     gene            1950..2330
                     /locus_tag="IXR40_002557"
     CDS             1950..2330
                     /locus_tag="IXR40_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HAQ4362352.1"
                     /translation="MSEQNQNLASNSSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVASG
                     DAQRLSENLKIMQKELQKIWQQLR"
     gene            2312..3226
                     /locus_tag="IXR40_002558"
     CDS             2312..3226
                     /locus_tag="IXR40_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HAQ4362353.1"
                     /translation="MATIKVSRTTSCSRAINYAEPRATIKTGINCDVDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQTAIYTHTDKDHIHN
                     HIVINSVNLETGKKFQAHGQAFLNKCYDLNDEICLAHNLPITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRIAIDQTMKNKKTRTYDQFCNSLKTLGIHCFNRGKNFTYELIHKKK
                     KVRSNRLGKDYEKETILHELDRRERTYNQQRTNELRRARASIRETAEEVRREQRTLTP
                     EQPEIRPARRNHEQHVERGTDHQQELSL"
     gene            3466..4155
                     /locus_tag="IXR40_002559"
     CDS             3466..4155
                     /locus_tag="IXR40_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362354.1"
                     /translation="MAFYLPYLLIFVSISGSIWLIYKIFQTRYSLKGSKIRFKRFFFL
                     GCIFSLIIVSSGLFGVLEGNKRVSRSILLGNVTQKYESARDKKKKEQALAQKMEEFTT
                     CYEEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYVKDTKI
                     EEACSDLFGDTNPWFASEEEKKEKQQSVTYERYEILLQQATNMQNPTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(4276..4362)
                     /locus_tag="IXR40_002560"
     CDS             complement(4276..4362)
                     /locus_tag="IXR40_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011302749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HAQ4362355.1"
                     /translation="MFELFICPLLVGVCVSLFSYWLNNRNKK"
     gene            5007..5744
                     /locus_tag="IXR40_002561"
     CDS             5007..5744
                     /locus_tag="IXR40_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015060391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HAQ4362356.1"
                     /translation="MSNDIVRYNNGLNSVPLRKFTPIDMDLFWGICSKMKRKGTKEEI
                     FTFKQIKELIDYNINARGDRFANDLIKMSKKIITLSFIYEDEKTYEQLNLFQKFKIDK
                     VNETLLIKVSEEFEYILNSIGTNFTRFELENMTNLKSSYVKELYRQLMAHKDRRSKKG
                     HWFVKIEDFRALLAIPESYRMRDIDKQIFAQAKKEFLNVNSTHPAIFKTFEIKKIKAY
                     KGNKIGSLQIYFEENIPSITLDNWLEK"
     gene            5772..6311
                     /locus_tag="IXR40_002562"
     CDS             5772..6311
                     /locus_tag="IXR40_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HAQ4362357.1"
                     /translation="MQPKETFTIKELSELFEISRQAISKHVDKLDPSLLAKNERGYKV
                     VLRSGVLQLASNLGNQRLLYRLHEYEQENDKNVYISSKNVIVNELLDKLREENEFLRE
                     QLSLKEQNNSNMQKLLDQQQQLTLQANQQIEKLQEQLQLAYTEETPEDESTTILSEET
                     ESIEKHTKKKKQKWWQLWK"
BASE COUNT         2729 a         1084 c         1177 g         2028 t
ORIGIN      
        1 aaaactaata tttgttaata ataaccaaaa gtattttagt tttaatacct tatatggaaa
       61 ggcaaaagat aactatacaa taactgatcc catagttaga gttattaatc cagaaataac
      121 agaatcatta ttttggggaa atatattgac tagtgatggt ggattatttt ttgatcagaa
      181 acatacttca aaccaaaact tttttaatca aattaatccg tatataaaag aatttaacct
      241 agaaaatatc ataaattttt cttattctgt ttttcaagaa actggtgaat tattatctca
      301 aaaaaaagta aataaattaa atgcatatct acaatatctt ttaatattag gattatttat
      361 aataattaat tttcaaatga tttttgttag ttttactata aattcaaaaa aaatagcttt
      421 aaaaaaaata tttggatatt caccaataag tcaagtttta gatttatgtt tactcccttt
      481 tacaatagag ttatttgcta ctatgtgttt tcaattgata ttttcaaaaa acacttactt
      541 gtattttata atttttatga tctttttaat aaatctaatt acttctatta ttatttataa
      601 aaaaaatagt tttaaatatt ttaaggagaa tattttatga tattatcagt tgagaatttc
      661 accctgtcaa ttaataaaaa aaagatcaaa caaaattgga acttttcaat atcagaaaaa
      721 gattttatta tagtaacagg aaaaagtggt agtggaaaaa ctactctgtt aaataattta
      781 agcctaatag ataaacaata taccggtaac ttattctatt ttgaaaagaa agtttctaaa
      841 catgatatac aacgtctacg aagaaatcat attagctatt tatttcaaaa ctatgctctt
      901 cttgaaaatc aaacagtaca atacaatttc gaattagcaa aaaagtttaa cagtaatatt
      961 tccaatgatc atatttataa tttattaaca gatttttctt tgccaaaaga tatcttaaaa
     1021 gaaaaaatct ttctcttaag cggtggagaa caacaaagaa tagcattaat tagaaatatg
     1081 ttaaaaccat ttgatatatt atttgcagat gaacctacag gaaatttaga taaagaaaac
     1141 tcaactttta taatgaactt tctgaaaaat ttaacagaaa aagaaaaaaa agccgttgta
     1201 ctagtaacac atgacttaaa tgttctaaac tatggaacta atattataga attataattt
     1261 ttacccgtga tgctagctga tttaaaacta gcaccacggg tatttatttt atattccatc
     1321 tctcctatcc caaaatttaa ataatcactt aataaaaagg aggcacccta gtgattttat
     1381 tgaaaaaaga gtatgaaaaa ttttatgata gacttattta ttctttgcaa ttgccaaaaa
     1441 aattaaaccg tcaattacaa aagacttatg aaactaaatc aactgaagaa tgggagagtt
     1501 attgctagat ttttggtaga agtaacaaaa agtggacata ttatcataat gactcgccga
     1561 aagtctgata aaaaattggc taaaaatatt gctgaatgtt taataaaact atcagtttta
     1621 gctaaatagt tagtagttta cacaaaaaag catttatgtt ttttgttgca aagtaacaat
     1681 ttcatcttcg gtgaaataag cgaaacttta caaaaagtgg ctagcatttg ctagcttttt
     1741 ttgtattgtg gagcgtggct tttgaggggg attcaagggg gagcttgcgc ccctttgaca
     1801 agcggttatt tgcactaaat acgtaggtat ttggctagca aatatagagc ttgccaaacc
     1861 cttttagtga gctttactca ttgtaccttt ttaggtacaa tggtattgcg aacgatacgt
     1921 ccgtaggacg tactgaaagg gtgggactta tgagcgaaca aaatcaaaat ttggctagca
     1981 attcttctaa aaaatatacc tatcgatccg agccaaaaca aatcagtttt cgagtgagcg
     2041 aatccgaatt tgcaaagctg aagcaatcgg ctgaagcttt gcaaatgagt gtgccggctt
     2101 tcgtgaaagc caaggcacaa aacgcgcgtc tggtgacacc gaaagtggcg ccagacattg
     2161 cccaggcaat cgcgcgcgat ttagccaaag ctggagggaa tatcaatcaa attgctaagt
     2221 ggtgcaatac acaccaacat gacgttgctt ctggtgacgc tcaacgttta tccgaaaacc
     2281 taaaaatcat gcaaaaggag ctacaaaaga tatggcaaca attaaggtaa gccgaaccac
     2341 ttcttgtagt cgtgcaatta attacgcaga accacgagca accattaaaa caggaataaa
     2401 ctgtgacgtc gattatgcca aaagtgaaat gaaacaaatt cgcatgctgt atggaaaaga
     2461 cgaccgtgta caggcacact tattgattca atcttttcga ccaggagaaa ttaccgctga
     2521 aaaagctaat caactagggg cagagtatgc aaaaaaaata gcccccgatc accaaacagc
     2581 tatttacaca catacagaca aagaccatat tcataatcac attgtcatta actccgttaa
     2641 tctggagact ggaaaaaaat ttcaagctca tggtcaagca tttctaaaca aatgttatga
     2701 cctaaatgac gagatttgtc ttgcacataa cttaccaatc actgagcgag gaaagaaacc
     2761 agaaaaacga accatgtctg aaataaaatt aaaagaaaaa aatgaacctg tttggaaaga
     2821 cgaaattcgg attgcgatcg atcaaacaat gaaaaacaaa aaaaccagaa cctatgacca
     2881 attttgtaat tccctcaaaa cattggggat tcattgcttc aatcgcggga aaaatttcac
     2941 ttacgaattg atccacaaaa agaaaaaagt acgatccaac agactaggaa aggactacga
     3001 aaaggagacg attttacatg agctggacag acgagaacga acctataacc aacagcgaac
     3061 caacgagcta cgaagagctc gagctagcat tcgcgaaact gcagaagaag tacgaagaga
     3121 acaacgaact cttacgcctg aacaaccgga aattagaccg gctcgaagaa accatgaaca
     3181 acacgttgaa agaggaacag accaccaaca agaattatcg ctctaaaacg ttaaaagaca
     3241 tagaaaacga aataaagaaa caacgtgctt ttctcgttcc ttatacgcaa gaaaggatac
     3301 aaactacgat tgatttacaa gttaaaaaac tccatcaaga gctattagac cagcgaaata
     3361 aggaacagaa aaaggtgctt attcaacgat cattggattt tcttgccccc ttatgttgct
     3421 tagtcctgac actgttcgca ttttggttag tatggggagg ctaaaatggc attttattta
     3481 ccctatctac tcatttttgt tagtatttca ggaagtattt ggctcatcta taaaattttt
     3541 caaacaagat attcattaaa aggctctaaa attcgattta agcgattttt ctttcttggc
     3601 tgtatatttt ccttgataat cgtttcaagc ggcttattcg gcgttttaga gggaaataag
     3661 cgcgtttcta gaagtatttt attaggaaat gtcactcaaa agtatgaatc agcgcgtgat
     3721 aaaaagaaaa aagagcaagc attagcacaa aaaatggaag agtttaccac ttgttatgag
     3781 gaaatgaacg atatttttgt gaatcaagaa aaacgtttga cggataaaaa catggaaaaa
     3841 ctcactcgtc tttatcaaaa cttgccagaa aaacagcaaa aagaggttca agacaactat
     3901 gagcgaacca aaaaagacgt gcaatatgta aaagatacaa agatagaaga agcctgtagt
     3961 gatctatttg gagacacaaa cccttggttt gccagtgaag aagaaaaaaa agaaaaacaa
     4021 caatctgtca catatgaacg ctatgaaatc ttacttcaac aagcaactaa catgcaaaat
     4081 ccgacaaaaa aagaaaccgc cttaaactat ctaaaaagtg tcaaggaatg gttagatcag
     4141 caacaacaaa attgaatttg atttaaaatc atgttaaact gaatgtgcaa atgatcaaac
     4201 attagataca cgaaagcccc agagaggtcg gattctctgg ggcttttttt caggttgatg
     4261 tcgcctttat tgattttact tcttgtttcg gttattcaac caataactga ataaagagac
     4321 acaaactcct acaagaaggg ggcaaatgaa cagttcaaac attagataca cctccttcca
     4381 gtcgcaagac tgtcggatag gcgacaagtt attatatctt aaaaaattaa atttgtgtgg
     4441 tgtttttaag tatcacttgt tttagggttg ttagggcttg ccctgaccgc ctgtaaggcg
     4501 cttctcgact agattaaggg aaattaatca agaattgtct tagaacggct tagacaagct
     4561 ttcagagtct cacacctcct ctttgaacaa cggttttagc aaaggagccg gaggcgactg
     4621 cgcagtataa tatgagagca tagcgatcac acctttttag cgaccgtagg gagcaagttt
     4681 tccagtttag aaaaattcgc gaaccttttt ggaggaaaaa gtaggagttt tttaggcggg
     4741 aaattcaatg tgctcttaag atatactgtt agatatactg ttagatatac tgttaataat
     4801 aactgttagg gattagcaac cttatgggag agtaagtatt gacataggta gtgggggata
     4861 aattgtcaca ctatggggga taaattgtca cactatgggg gataaattgt cacactatgg
     4921 gggataaatt gtcacactat gggggataaa ttgtgtttta catcctctta tgtctatgat
     4981 aacataattt attgaggtga tttttattga gtaacgatat agttcgatat aataatggat
     5041 taaattctgt ccctttaaga aaatttaccc ctatagatat ggatttattt tggggaatat
     5101 gttctaaaat gaaaagaaaa ggtacaaaag aagaaatttt tacatttaaa caaataaaag
     5161 aattaattga ttacaatata aatgcacgtg gcgaccgttt tgctaatgat ttaataaaaa
     5221 tgtcaaaaaa aatcattact ttgtctttta tttatgaaga cgaaaaaaca tatgaacaat
     5281 taaatctgtt tcaaaaattt aaaatcgata aagtgaatga aacattatta ataaaggttt
     5341 ctgaagaatt tgaatatata cttaattcaa tcggaactaa ttttactcgt ttcgaattag
     5401 aaaatatgac aaacttaaag agtagctacg ttaaagagtt atatcgccaa cttatggctc
     5461 ataaagacag aagatctaaa aaaggtcact ggtttgtaaa aatagaagat tttagagctc
     5521 tattagcaat accagaaagt tatcgcatga gagatattga taaacaaatt tttgcccaag
     5581 cgaaaaaaga atttttaaac gttaattcaa ctcaccctgc tatttttaaa acttttgaaa
     5641 tcaaaaaaat taaagcctac aaaggaaata agataggatc tctgcaaatt tattttgaag
     5701 aaaatatacc ttcaattacc ttagataatt ggttagagaa ataataccta acaatttagg
     5761 aggcaattat catgcaaccc aaagaaacct ttacaataaa ggaattatct gaattatttg
     5821 aaataagtag gcaagcaatc tctaaacatg ttgataaatt agacccgtcc ttattagcta
     5881 aaaatgagcg tggttataag gttgtattac gttctggagt attgcaactt gctagcaact
     5941 taggtaacca aaggttacta tataggttgc atgagtatga acaagaaaac gataaaaacg
     6001 tttatatatc aagcaaaaac gtgattgtaa acgagttgct agataagttg cgtgaagaaa
     6061 atgaattttt acgagaacaa ctttccctca aagagcaaaa taattctaat atgcaaaaat
     6121 tactcgacca gcaacaacag ctcaccctac aggcaaatca acagatcgaa aaactgcaag
     6181 aacagttaca attagcttat acggaagaaa ctccagaaga tgaatcaact actattcttt
     6241 ctgaagaaac agaatcgata gaaaaacaca caaaaaagaa gaagcaaaaa tggtggcaac
     6301 tttggaaata actggaggga acattcatga caagaaaaaa tcttctattc ggttctattt
     6361 tactaggaat tctaggcttc agtccgatgt tattgtcagt aatcaataaa gggaataaac
     6421 atggtgaatt gaaattgaat ccaaattatt acaacagtcc taacgaagaa ttgtttgtaa
     6481 aagagacgga taaataataa aaaagactgc tcttccgagc agccagttaa aaaataatga
     6541 gtgtttattc ttgaaaaagc acgcgcttat gaagcgctac caaaaattta ccatatttta
     6601 caaaaaataa caagtcttaa aaaaatgaca gataaaaatg cacaaagaat tagatataga
     6661 taaccgcgaa aaatcaagct ttagaaagtt gcttttagct agaccaatta aaaatcacaa
     6721 agtgagcgtc tctatccatt ggtagagggg ctacttggca tagtcgacat tatgtcaact
     6781 atgcaattaa ataactaact acttcatatt agcttaataa aataatcaaa ataactaggg
     6841 ggaaaaacat tgtataaaaa aatttttcat tttttaaata agaatagtaa atataaaaat
     6901 aatttaagat atctattact attaatccag atagagcaaa ccaagtaaat attccatgtg
     6961 taaagctaaa aaaattcatt tgaatcaatt caaataaacc taatatagta acaaatat
//
LOCUS       DACGEU010000117         6869 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.121, whole genome shotgun sequence.
ACCESSION   DACGEU010000117 DACGEU010000000
VERSION     DACGEU010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6869)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6869)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6869
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.121"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            <1..227
                     /locus_tag="IXR40_002563"
     CDS             <1..227
                     /locus_tag="IXR40_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HAQ4362358.1"
                     /translation="KTTEFDILHALMSTPNKVFSRSDLIEKVKGIEFDGLDRSIDSHI
                     KNLRHKIENDAKSPMYILTVHGTGYRFGGH"
     gene            227..574
                     /locus_tag="IXR40_002564"
     CDS             227..574
                     /locus_tag="IXR40_002564"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362359.1"
                     /translation="MRKRTIKTQLAVSFLAIATLIIGSISLVALSLMNNHFSKYVEER
                     QEDLLNQYVYTIDLLWLNSGETWNSEELAALSEKVLENNIYFSIEDEQGNMVWELTGK
                     DLKSAQEKLKKMH"
     gene            571..1620
                     /locus_tag="IXR40_002565"
     CDS             571..1620
                     /locus_tag="IXR40_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAQ4362360.1"
                     /translation="MKVSEKNSVKLDETIEVKKKLINDGNEFGKVTFYYFGPFAYTEH
                     DALFISSMKQSLMYVAIAALLVSFILASWISARLGLPLKHVSDFTHKLTRGEYADKIP
                     QETSIIEINSLIDSLNDLSNQLEKQHGLRKRLTTDISHELRTPLATLKGNVEGMIDGV
                     WKITPERLQSCYDEIDRLTRLIGNIEIINKIEAKYDHLNKTEFNIYKLIESVIENFAS
                     KIESKNLHVEIQGDNINISADKDKMNQVVINLLNNAIKFTQKEGTIKFSISKNKDHVL
                     LIVEDNGIGIEKDQQLHIFDRFYMADPSRSRALGGQGIGLAIVKSVIEAHKGSITVKS
                     KLGLGTKFVIKLPFQ"
     gene            1635..1841
                     /locus_tag="IXR40_002566"
     CDS             1635..1841
                     /locus_tag="IXR40_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362361.1"
                     /translation="MFQKQIKIAKLVCECWAKKIFFQLISIDSVEKVHLDILSNSVVI
                     FSKKDLSIATIKKEVFGLQIYEMT"
     gene            1862..2458
                     /locus_tag="IXR40_002567"
     CDS             1862..2458
                     /locus_tag="IXR40_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdhK family protein"
                     /protein_id="HAQ4362362.1"
                     /translation="MKTVKKMTKLVFASLGIIVFLGACSNQSESNNSNSTNEESTSTA
                     SSEMNSMEGMNHEGMVPSSMKDAANPKFPVGSNVILLGDHMEGMKGANAQVVGAFDTT
                     MYEVSYEPKTGGPMVNNHRWVVQEELKDTETVANEGDTVILNADHMDGMMGAEAKVDK
                     SITGTVYVVNYTPTDGQEEVKNHMWVTEDEMEYDENNE"
     gene            3410..4009
                     /locus_tag="IXR40_002568"
     CDS             3410..4009
                     /locus_tag="IXR40_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAQ4362363.1"
                     /translation="MKSVEPIRDKKKIDAMKAILASGKYGQRNLVLFSIGINTAYRIS
                     DLRQLKLRDVLEISRGRVIVKERLAMKEQKTAKHNSVFISNKLRKVILDYVQSEFPEQ
                     LQAQDFSKYLFPSRKGADTPLTRQSLWRIIHEAGTAVGLKEIGPHSMRKTFGYFLYKQ
                     GTKTEIIQSLLNHSSQRETLRYIGITQEDKDTAVKSLDL"
     gene            4058..4774
                     /locus_tag="IXR40_002569"
     CDS             4058..4774
                     /locus_tag="IXR40_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HAQ4362364.1"
                     /translation="MNEEKQPNFPDKYHLSRKESVYLLKKNIVELVYNAGKFEGLNTT
                     LLQTEGIIKYNRANNVAVDDVLTVVNLKRGFEMLLNDVQEPLLETSKRINRIVAAEDA
                     LFPGEIRTGGVELSTIQGRYVPPMLTEDEVNNQYGEIMNQEISDTEKALRLFLFISKN
                     QIFWNGNVGTALLIANKIMFSNGLGLLSIPENVFMKFNELLSKYCNSNLLVNESNIIS
                     FLYEQCIFGINYLKIIQHTI"
     gene            4788..5567
                     /locus_tag="IXR40_002570"
     CDS             4788..5567
                     /locus_tag="IXR40_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002396205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection family protein"
                     /protein_id="HAQ4362365.1"
                     /translation="MMTIDEAKQLATYFSVGSAGYILDFTNVTWNIFTKKIVGIEIQN
                     HYGGSKGVSFQKFLLDDQFDDSLKNRLIQSLKGIMDRDKKYESTEMNPIVQLLFEEVF
                     KEDTSTALRKMKFSSEIDLLYIRQLPIRIQTDIKNKDFDSVLTKANTLIDEVLKFIIE
                     NTEGPSVNINLFKSKELRKEVFGRLNIKTEKDMDNRIKALVGALNTLSDKILEMRNSQ
                     GDAHAHGSNRIVIKEEEAILVANSSMVLCEYVFTKYKGLNR"
     gene            5650..6006
                     /locus_tag="IXR40_002571"
     CDS             5650..6006
                     /locus_tag="IXR40_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAQ4362366.1"
                     /translation="MEKISFETFKRPNGHDEFLEWLETLPKKDSAKLLRTIEETEKNG
                     MLVAQRLKWVKKLDTNLYELRSKVGSNIQRAIYFHVDNGRYVITHGFTKKTEKTPITE
                     LKHAKELREEWFTNDD"
     gene            5996..6262
                     /locus_tag="IXR40_002572"
     CDS             5996..6262
                     /locus_tag="IXR40_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4362367.1"
                     /translation="MMIKKLIEEKKKDKDFAEAYDREGRKLETAVALYHAREEAGLTQ
                     AELAQKAHTTQSTIARIERGDNVSFDKLDDIARALGKKLVVEFA"
     gene            6421..6699
                     /locus_tag="IXR40_002573"
     CDS             6421..6699
                     /locus_tag="IXR40_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362368.1"
                     /translation="MKTINLIKVFIASPGDIAAKRNEVEETIYRWNIENTDNTKVILM
                     PIRWETNAIPTYVNNSSGQSVINKQIVENRVLLQSFKNKISFCIISSF"
     gene            complement(6696..>6869)
                     /locus_tag="IXR40_002574"
     CDS             complement(6696..>6869)
                     /locus_tag="IXR40_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010868911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HAQ4362369.1"
                     /translation="HRSIKRRHKLYQSLRTASTTIKGMETIRGIYKKSRKEGTLFGFS
                     VCTEIRILLGIPA"
BASE COUNT         2527 a          957 c         1333 g         2052 t
ORIGIN      
        1 ttaaaacaac tgaatttgat attctacacg ctctaatgtc cacacctaat aaagtctttt
       61 ctcgtagtga tttgatagag aaagttaagg gaatagaatt tgatggacta gataggagca
      121 tcgattctca tataaaaaac ttaagacata aaattgagaa tgatgctaaa tcacctatgt
      181 atattttgac agtccatggt acaggataca gatttggtgg ccactaatga gaaaaagaac
      241 gataaaaact caattagctg tttccttttt agcaatcgca acattaataa taggatcgat
      301 tagtttagtc gcattaagtt tgatgaacaa tcattttagt aaatacgtgg aagagcggca
      361 agaagatttg ttgaatcagt atgtatatac aattgattta ttgtggttaa atagtgggga
      421 aacatggaat agtgaagaac ttgcagcact atctgagaaa gtattagaga ataatattta
      481 tttttctata gaagacgaac aaggcaacat ggtttgggaa cttactggaa aagatttgaa
      541 gtcagcacag gagaaactga aaaaaatgca ttgaaagttt ctgagaaaaa cagtgtgaaa
      601 ctagacgaaa caatagaagt gaaaaagaag ttaattaatg atggaaacga gtttggaaaa
      661 gtaacgtttt attatttcgg accttttgct tatacagagc acgatgcctt gtttatctcc
      721 agtatgaaac aaagtttaat gtatgttgca attgcagctc ttcttgtatc attcatactt
      781 gcttcgtgga tctctgctag attaggattg ccactaaagc atgtaagcga ttttacacat
      841 aaattaactc gtggggaata tgctgataaa atcccacaag aaacttcaat tattgaaata
      901 aattccttaa ttgattccct aaatgattta agtaatcagt tggagaaaca gcatgggctt
      961 cgaaaaagat taactaccga tatttcacat gaattaagaa ctccattagc tacgcttaaa
     1021 ggcaatgtgg aaggaatgat tgacggagtc tggaaaataa ctcccgagcg cctacaatct
     1081 tgttatgacg aaatagatcg tctaactcgt ttaattggaa atatagaaat aatcaacaaa
     1141 attgaagcaa aatatgatca tttaaataaa actgagttta acatatataa gttgattgaa
     1201 tccgttattg aaaatttcgc cagcaaaatt gagtcaaaaa accttcatgt tgaaatccaa
     1261 ggggataaca tcaatatatc tgcagataaa gataaaatga accaagttgt tatcaatctt
     1321 ttgaataatg ctattaaatt tacgcaaaag gagggaacca ttaagttttc tataagtaaa
     1381 aataaagacc atgttctttt aattgttgaa gacaacggca tcggtataga aaaagatcag
     1441 caacttcata tttttgatag attttatatg gctgacccct ccagaagtag agctttaggg
     1501 gggcaaggta tcggattagc tattgtaaag agcgttattg aagcgcataa aggtagtata
     1561 actgtaaaaa gtaaattagg tctaggaact aaatttgtta taaagttacc atttcaataa
     1621 aggaggagag ttatttgttt caaaaacaga taaaaattgc taaactagta tgtgaatgtt
     1681 gggcaaaaaa aatatttttt caactgattt cgatagatag tgtcgaaaaa gttcatttag
     1741 atatcttatc aaattctgta gtaatctttt ctaagaagga cttatcaata gctacaatta
     1801 aaaaagaagt ttttggatta caaatttatg agatgaccta aatgtgatta attaaaggag
     1861 gatgaagaca gtgaaaaaga tgacaaaatt agtatttgca agtcttggaa ttattgtatt
     1921 tttaggagcg tgtagcaatc aaagtgaatc gaataattct aatagcacaa acgaggaatc
     1981 gacttctaca gcgtctagtg aaatgaatag tatggaggga atgaatcacg aaggtatggt
     2041 tccttcttca atgaaagatg ctgcgaaccc taaattcccg gtgggaagta atgttatact
     2101 gctaggcgat catatggaag ggatgaaagg tgcaaatgct caagttgtag gggcctttga
     2161 tactacaatg tatgaagtaa gctatgagcc aaaaactggg ggaccaatgg ttaacaatca
     2221 tcgatgggta gtacaagaag agttaaaaga tactgagact gtagcaaatg agggcgatac
     2281 tgttatcttg aatgccgatc acatggatgg gatgatggga gctgaagcaa aagtagataa
     2341 atctattaca ggaactgttt acgttgttaa ttacactcca accgatggtc aagaagaagt
     2401 taagaatcat atgtgggtaa ctgaagatga gatggaatat gacgaaaata atgagtaatt
     2461 ttatatacta aaccaacaag ctggtacatg gtcttcgtat tctcaacatg aggaatatga
     2521 gctctttgtt aataaggact gatgagttgt gcaaaatcaa atctgggtca gaacgaacct
     2581 cattctggct cagatttttg gctcttcgac atttagtgct ggtagagaga caactgaaaa
     2641 tttagtcata accagttagg cagagtgctt aactggtttt tgttcgcatt tattattctt
     2701 ttgatattgg ctgcttgccc ttcaatttta tttggtttct taatcaactc ttcatataac
     2761 cccaaatcat atattaatga ggtgcctcct attcctataa atctatctct tctttaatag
     2821 tatgagaaaa gtctactctt gtagatttaa attgtcaaca aaaaatttac agatgtaaat
     2881 gataagttga atagagaaag ataaattatt tttttggtat tcatataagg ttaattatgt
     2941 attatcacaa aatgattgtt gtcgaataac taaaagtgtc aaaacaatga tgaaatcatt
     3001 tagttcttat aaattagaca agagaaaata aatattccat atctacttta ttggatccat
     3061 aacatgacta aattctgaat actttttaaa gcttatcatt tggtaaaact gaatataagt
     3121 taattatata gactgaaaat tttgaatttt cagaatagaa taacttaaaa gtactgacaa
     3181 attttttaaa ggggcaatat taatgttctg agataatcaa atcttaccga aaatatcaaa
     3241 agtccaatgt gacacaattg gattttgtca cattcgttaa aatcgctcca tccttagagg
     3301 ctctaatagg aaatcacttt tcttttagcg ccttttttct atagcttgtt taaatgtgac
     3361 ttattatctg ttataatcgt attaagtaac atttgagagg tgtctaaaaa tgaaaagcgt
     3421 ggaaccgatt cgcgacaaaa aaaagatcga tgccatgaag gccattttgg cttccggaaa
     3481 atatgggcaa cgaaatttgg tgcttttttc gatcgggatc aatacagcct atcgaatctc
     3541 cgatttaaga cagttaaaat taagggatgt gctagaaatt tcccgtgggc gggtgatcgt
     3601 caaagaacgt ctggccatga aggaacaaaa aacggccaaa cacaattcgg tcttcatttc
     3661 gaacaaattg cgaaaagtga ttcttgatta tgttcaatcc gaatttcctg agcagttgca
     3721 agcacaagac ttcagcaagt atttgtttcc aagtcgaaaa ggagcagata cgcctttgac
     3781 ccgacaaagc ctttggcgga tcattcatga agcaggaact gcagttgggt taaaagaaat
     3841 tggtccccat tcgatgcgta agacctttgg ctatttttta tacaagcaag gaaccaaaac
     3901 agagatcatt cagtcgctgc taaaccattc ttcacaacgg gagaccttac gctatattgg
     3961 aatcacccag gaagacaaag atactgcagt aaagagtttg gatttatgac agaataatgc
     4021 cctatataat agaaggaaaa attcaagagg tgagaaaatg aacgaagaaa agcagcctaa
     4081 ctttcctgat aaatatcact tatctcgcaa agagtctgtg tatttattga agaaaaacat
     4141 tgtagaactg gtgtataatg cggggaaatt tgaagggtta aatacaacgt tgttacaaac
     4201 agaagggatt attaagtata atcgggccaa caacgtggct gtagatgatg tcctgaccgt
     4261 cgttaactta aaaagaggct ttgaaatgct tttaaatgac gtacaggagc ccctgttaga
     4321 gacaagtaag cggattaatc ggatcgttgc agcagaggat gcgctttttc ccggtgaaat
     4381 acgaaccggt ggggtagaat tatcgacgat tcaaggaaga tatgtgccac caatgttaac
     4441 tgaagacgag gtaaacaatc aatatggtga gataatgaat caagagatat cagatacgga
     4501 aaaagccctg cgactgtttc tattcatttc gaaaaatcaa atattctgga atggtaatgt
     4561 gggtacagcc ttgttgattg cgaataagat tatgtttagc aacggtttag gactattatc
     4621 aatacccgaa aatgtattta tgaaatttaa cgaactttta tcaaagtatt gcaacagtaa
     4681 tctattagtc aatgagtcaa atattatatc atttttatat gaacagtgta tctttggtat
     4741 taattatttg aaaataatcc aacatacaat ttaagaggta taagtaaatg atgactatag
     4801 acgaagcaaa acaattagca acttattttt cagttggttc agcgggatat attttagact
     4861 ttactaatgt aacgtggaac atatttacaa agaaaatcgt agggattgaa atacaaaatc
     4921 attatggggg ctcaaaggga gtatcctttc aaaagtttct gcttgacgat caatttgatg
     4981 attcgttaaa gaatcggtta atccaatctt taaaaggtat tatggatcga gataaaaaat
     5041 atgaatctac tgaaatgaat cccatagttc agttgctttt tgaggaagta tttaaagaag
     5101 atacttcaac tgcattaaga aaaatgaaat tttcaagcga gattgattta ctttatattc
     5161 ggcagctacc cattaggatt caaacagata ttaaaaacaa ggattttgac tctgttttga
     5221 caaaagcaaa tactttaata gatgaagttc taaaatttat tattgaaaat accgaaggac
     5281 cgagtgttaa tattaattta tttaagtcaa aagaattaag aaaagaagta tttggccgcc
     5341 tcaatattaa aactgaaaaa gatatggata atagaatcaa agcccttgtt ggagcactca
     5401 atacattatc agataaaata ctcgaaatga gaaatagtca aggagatgct catgcacatg
     5461 gctcaaatag aatagtaatt aaggaagaag aagcaattct tgttgcaaat tcttctatgg
     5521 ttttgtgcga gtatgtgttt actaagtata aaggattaaa tagataataa aatgcatatt
     5581 ttatagtata caattcgaat ttttatgtta tatactataa tataaaatca atatatgata
     5641 taattgggta tggaaaaaat atcttttgaa acatttaaaa gacccaatgg tcatgatgaa
     5701 tttttagaat ggttggaaac attaccaaaa aaagatagtg cgaagctttt acgtacaata
     5761 gaagaaacag aaaagaatgg gatgctagta gctcaacggt tgaaatgggt gaaaaaatta
     5821 gacactaatt tgtacgaatt aagaagtaag gtaggatcaa acatccaaag agccatctat
     5881 ttccatgtgg acaatggaag gtatgtcatt actcacggat ttactaaaaa aacggagaaa
     5941 acaccaataa ctgaactcaa gcatgcaaaa gaacttagag aggagtggtt cacaaatgat
     6001 gattaaaaaa ttgattgaag aaaagaaaaa agataaagat tttgcagaag catatgaccg
     6061 tgaaggaaga aaactcgaaa ctgcggttgc tctttatcat gctcgggagg aagcagggct
     6121 aactcaagcg gagcttgcac aaaaagcaca tacaactcaa tctactattg ctcgaattga
     6181 gagaggggat aacgtatctt tcgataaact tgatgatatc gccagggcat taggtaaaaa
     6241 gctggtagta gaatttgctt aaaagcgagt tgaaaatata tctataatag gctcctaact
     6301 aatcaattag tttagtgggc ctttttttac tagatagata aaggttgtac tatagtgtaa
     6361 aagacaataa attttatact aaaattactt taaagagaac tagagagaaa ggtacaataa
     6421 atgaaaacca taaatcttat aaaagtattt atagcatcac caggtgatat agcagcaaaa
     6481 aggaatgaag tagaagaaac catatataga tggaatatag aaaatacaga taatacaaaa
     6541 gtgattttga tgcctatacg atgggaaact aatgcgattc ctacttatgt aaataatagc
     6601 tctgggcaaa gtgttattaa taaacaaatt gtagaaaata gggttctgct gcaaagtttt
     6661 aaaaataaaa tcagtttttg tattatttct tcattttaag ctggaattcc caataatatc
     6721 ctgatttcag tgcagactga aaagccgaag agagtgcctt cttttcggct tttcttgtag
     6781 attcctcgaa tggtttccat ccctttaatt gtggtggaag ctgtacgtag actttgatac
     6841 aatttatgtc gacgttttat cgatcgatg
//
LOCUS       DACGEU010000118         6849 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.122, whole genome shotgun sequence.
ACCESSION   DACGEU010000118 DACGEU010000000
VERSION     DACGEU010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6849)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6849)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6849
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.122"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..182)
                     /locus_tag="IXR40_002575"
     CDS             complement(<1..182)
                     /locus_tag="IXR40_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAQ4362370.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNS"
     gene            517..951
                     /locus_tag="IXR40_002576"
     CDS             517..951
                     /locus_tag="IXR40_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAQ4362371.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            974..1294
                     /locus_tag="IXR40_002577"
     CDS             974..1294
                     /locus_tag="IXR40_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362372.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            1435..1626
                     /locus_tag="IXR40_002578"
     CDS             1435..1626
                     /locus_tag="IXR40_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362373.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(1697..1954)
                     /locus_tag="IXR40_002579"
     CDS             complement(1697..1954)
                     /locus_tag="IXR40_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HAQ4362374.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            2112..2375
                     /locus_tag="IXR40_002580"
     CDS             2112..2375
                     /locus_tag="IXR40_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362375.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            2399..2587
                     /locus_tag="IXR40_002581"
     CDS             2399..2587
                     /locus_tag="IXR40_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362376.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(2670..2855)
                     /locus_tag="IXR40_002582"
     CDS             complement(2670..2855)
                     /locus_tag="IXR40_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362377.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            3070..3441
                     /locus_tag="IXR40_002583"
     CDS             3070..3441
                     /locus_tag="IXR40_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAQ4362378.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            complement(3591..3663)
                     /locus_tag="IXR40_002584"
     tRNA            complement(3591..3663)
                     /locus_tag="IXR40_002584"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3628..3630),aa:Gln,seq:ctg)
     gene            complement(3709..4137)
                     /locus_tag="IXR40_002585"
     CDS             complement(3709..4137)
                     /locus_tag="IXR40_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362379.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            complement(4197..4955)
                     /locus_tag="IXR40_002586"
     CDS             complement(4197..4955)
                     /locus_tag="IXR40_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HAQ4362380.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            5250..5447
                     /locus_tag="IXR40_002587"
     CDS             5250..5447
                     /locus_tag="IXR40_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362381.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            5553..6035
                     /locus_tag="IXR40_002588"
     CDS             5553..6035
                     /locus_tag="IXR40_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362382.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(6093..6689)
                     /locus_tag="IXR40_002589"
     CDS             complement(6093..6689)
                     /locus_tag="IXR40_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HAQ4362383.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAEEKEYMNDADRFRVFG"
BASE COUNT         2325 a         1055 c         1346 g         2123 t
ORIGIN      
        1 gaatttgatt ctgcaatggc attgatcaag gagttatcac caacgtattt ttgagaaatc
       61 gttgatagag tatcacctga ttgaacggta taagcttcgt ccgcatgagc agtcgttccc
      121 atgaagaatg cagcgccggc agccaaagtt gttccaaaaa gtaaagtttt aagtgatgtc
      181 atgaaaaatc tcctttattc gttaaaaagt tttatttgtt gtgttcaacg aggaatactt
      241 taacacgtga aaatatttca taggtaaaag aagcatgaca atttatgaca aatccacgtt
      301 ttttgtaaca gaatgatgtt cgctcgatgt gaaaaatgat gaggaatttc acataatgca
      361 gaaataatgg gattagaaca ggtgttctga tgagaaaaga aatgtataaa taacttgaaa
      421 gaaattgctt ttgttcatca ttttatttac atattgcgta tattttttgt atttttgctt
      481 gagatgttac aataaaagaa aaaggaggcg gttccaatga gtaaaagata ccagaacatc
      541 atggtagcag ttgacggatc aagacaatcg atcaaagcgt tcgctgaagc ccttgactta
      601 gcaaaggaca atgaagccca cttatttatc gtgtcaatca tcaacaaagt tgagctgacc
      661 catagtgcct atgccttttc aaaaatctat gcagatgaaa aacaaagaac agaagtagcc
      721 atgctgaaaa aaatcaatga tgccaaagag tacggcattg ctgagatcca cgcaatagtt
      781 gaaactggag atccaagaaa tttgattgcc aatgtcatcc ctggacaaga aaatattgat
      841 ttgatcgtta tgggagcgac aggaaaaggt gctatacaac aagcattagt tggatcgacc
      901 gcttcttatg tcgtatcaca tgccccttgc agtgtgttgg tcgtgaagta atgagataag
      961 ggaggaatag aaaatggttc gtcctcaaga agtccgtgcg ccaaaagaaa aaatagaaat
     1021 tttagcaatt attgaagacg gcacacaaac aaagaaggga tactcgatcg ctttagtaaa
     1081 gtggaaagga aaaaaaggtg ttgctctgag atgggatgga gataaccaac aagataaagg
     1141 attccctgtc acagctaacg gttatcatcc agcgtggttt gttctgcctg ataaatttat
     1201 ggaattatac agctatgatt atgcaagagc cgcagcatca atcaaagcat tagataaatt
     1261 aacagaagag cagaatgaaa tggaggaaaa ataaaaaaga cgaaccaatc agcctttaga
     1321 aaactgatta gttcgaggag taaaaatgaa aaaaggttat ttgggatgaa actagaataa
     1381 tgcgtataac ttaaataaaa cttaaagcaa taaaatggca agagggtgag gcaaatggaa
     1441 gcaggaaaag tattacagga agtaaaagca ctatgtgcag ataaaaaata tgaagaagcg
     1501 aaaagcctga tcgaaaagaa caaagaaaat ttggaagaaa agtacccgat cgcacaagaa
     1561 tttatagaat taaaacaagg aacgatcctt caccgattca aacatttttt tggtataaca
     1621 gaatagaaaa aacgattaaa gatcggcaga aatttgctgc atctttaatc gttttctttt
     1681 taaacatgcg agggattcaa ttctgattct tatataaaaa atagatccaa ataataagaa
     1741 aaattactga aagcgtcaat tcgatgatgt gtgttattaa tacagacgtt gtttcccaat
     1801 gcctaaaaga aaaaatttga taagtaaaat atacagcagg taaagaggcc agtaaaactg
     1861 aaaacttctt ttttgtccat tttatgtaat agaaaagaat gcttatcata ataaaaaaag
     1921 gaatataaaa aacaaattga ccgatcgcga tcatactatt gcctccgata aataaagtcc
     1981 atgatacaaa ataacacttt gtgcgaaatg gcgcaagcag ttttgtggat ttatccggta
     2041 aaatctgtat cgattttgaa attagaggag aaacttgcta taatcaaagt gaaagaagga
     2101 gtgggatttt catggatcat gtagtgttag aaatcgattt gcatttgatc aataatattc
     2161 gggtgattta ctatgttgta agtaacagtg tcgaacaacg tgtactgacg aataaaataa
     2221 atggtatttt agcaaagaaa gacgttcacc gattcaataa tggtgaagga agttattata
     2281 gtatcccagt agaaaaaatt atttatacga cagtcaaagt cagagaagat ctagatacca
     2341 aaaaagcata tgaacctatt tttacaactt attgattgac agcagatgga ggaaaaaaat
     2401 gaatccatat gaacaactta ttcaagattt gatcgatgga aaaatcgaaa agattgatgt
     2461 aaaaagagaa gaattaatgg cttttcgaga agcgtggctg aagttggaga atcgtaaata
     2521 tgtggtggga aaagcctcac tgaacggcaa tgtgacttat cattacgatc cgacacgttt
     2581 attttagtat gaagtattca gaaaagaacc aaaggaggac gatgcagcag cattgtcctc
     2641 ctttgatttt acaaaagtga aagttttact tatttgaata gatttttaaa tttgtttttg
     2701 acactgtcga tatttacatc ttttaaaaga ttttgggctt tctctttata aggtcctaat
     2761 tgttctttat gttcttcgat aaatcgtttt gcgccatcga aattgccgtt cttaatcatt
     2821 tccttgactt tttgaaataa ttcttcttga ttcattttga acacatcctt tgctatcaac
     2881 atgatttttt acatggacaa aacgagaaaa actgatttat ccacacgtca ataatatcaa
     2941 ataacgatca tttttactaa aaaaacactc gattctcgct tctaaagtag gagaaaaatc
     3001 tccaacttgg gacggatgga atttctttaa ctgacccata tactgaatat ataacaagga
     3061 ggtagaaaga tgaaagtgat taaatatttg attggactgg cggcgattag tggtattttg
     3121 ctatttggac tgaaatatta tactgaagga agttatggag aaatccctgg tatacttgat
     3181 cagctaaatc cattagttga aaaaggagag gtctatgtaa agacacaaaa accagaggaa
     3241 gtaaatgaat atggtacagc aaggtatgtg cagaaagctg ctgatgccaa tgggaaagaa
     3301 cgaacggttg aatttaatgg tctttctgtg ttaaaagaaa atcattattt gaaaattagc
     3361 aataaaggag cacacataga aacgtatgag gaagttccta gagaaaaagt tccggagaaa
     3421 gcattagcaa ttattgggta aatcagtttt tgtattaaga atacgcccga ttttattatt
     3481 cataatttaa ttatgtaaac taaatacaag tagtaaaaat aatacaataa tccccctgca
     3541 aaaagattgt tcttttacag ggggttcatt ttttcagcaa gcacatcaaa ttgggatggc
     3601 agggttcgaa cctacaattg cttgattcag agtcaagtgc cttaccagtt tggctacatc
     3661 ccatttattc aacaaaataa tcatagcact ttcctaaaaa aacgcaagtt atttttcttg
     3721 atcggatagt tgttgcttta ctcgtaaaag gcggcgtact agtttctttt ctaatccagc
     3781 aggaagggca atcagttctg ctactgacaa gacggtgtcc aataactgat attctttgac
     3841 aggttcattc ataatatgat agatgtttgc taaacgttca atatattcaa agcgagtata
     3901 ctctgttcga gcaattagaa atttcaataa atcggtggct ttctcgtact cttgatctgc
     3961 gtaataaaca agagattgac gatacaattt gatttccagt tcattgaggg tagcaggtct
     4021 gcgacgctcg ttccactcat taatagagac tttaccttga acatttccct tgcagtcacg
     4081 gacaaaaata atcggaattt catttggatc cattttttta tgtgtgaatt tttccattat
     4141 ctacgctccc ttcaaaggtt tggtatcttg agtataaggg atttttgttt gaattactag
     4201 cttttctcca aagttagcat ctgtccaccc attgcagtga aaatcgccga aaaatcgttg
     4261 atcggtactg ctcgattttt tacaccatag ggatcgttga cataaatatt ttctttgtca
     4321 tatccagtga ctacacaagc atgaacaaga ggagtgactc ttacttctcc attatttgtg
     4381 gtccaagtca taaaatcagt ttcatctggg acttcaaaat tgatagtcac agaagtccag
     4441 acaggatttc ctttagatag tgcttttttg atatcatcga gttgagcatc ggtttttgga
     4501 aaagtgtgat aatccgtttg gacgatttgc tgagcaaggg aggcaactgg gggaacatag
     4561 acgaccatag cccagtctcc gccactgata tcaccaacaa atccttcatt aggatcgcca
     4621 tgagtcccat ctgcattgaa aacagggacg taatccaatt gctcagctaa ctggttttta
     4681 gttgtttcat aaccataaaa agataaaagc atagaaagcg aagtgacttc acagccattt
     4741 tctaaagaag gagaatcaaa ctggctctct aatggaacat ctagtaaaac ttctgctttc
     4801 tcttttgtct ttttcgtttt ttgtgttgaa cttttttgtg cagtgttcat tgtatgttct
     4861 ggagaatgga tatgtaggta ataacttgta ccgcttaata aaagagcagc tgtgccccct
     4921 agaaacaata gttttttgaa cgtttttttc ttcatttgaa atctcccttt tcagctgttt
     4981 atctttccta ttataaatgt atttttattg gaaatggaag tattatattt taatatgtag
     5041 gaaataatta gtttttaagg aatatgtttt aattttttga aaaaaattct tctaaataca
     5101 acagctgttt taattgtgaa aacgaaaaca gtacgctata atgcctgtaa ggttgatttt
     5161 taactgtaaa taaaaatcaa tgagttaaat ctccaaagaa atagcagtgg taatgtggag
     5221 aaaagttcca gcagtttagg aggattttga tgacggaaga aatgattaat ttaggagaac
     5281 aatatgcatg caaaccaatt ggttttacaa aaacggtcat tggtgaagtt gtatcaaaaa
     5341 tgacaaactg cgccgtggtc aaagttgccc aatgtgctgc agaggaccaa gaattattag
     5401 atgaaaaagc aagcatggtt gttgcaaaat atgatacatt tgaataaaga aaacaattgg
     5461 acgtgcggcg tgctgcaagt ccaatttctt tgagaaggta aatcagtatt cttttcctat
     5521 tttctggaga agaaaaagcg aggcgagttg tcatggtaac attctttacg gttctattgt
     5581 ttttattcgt tgttgtgatg tttttatttc tttggctggt tcgaaaagaa attatttatc
     5641 ggactgtgcg aaatcgatgg gtctacttgg tgataccctt cttagtgtca ctagtcattt
     5701 ggtatacact catcagtcat cctacagcag atgaattggc aaaagggatc ttgtcagcaa
     5761 tgatttttat tagttttttg ttggacagta gaggaatcac agaagaagga cttgttttga
     5821 atagctttga caaaaaaggt gttccttttt ctgagatcaa taaaattgta ttatatcagc
     5881 caaaaggttc taaaatcgta aaaatgaatt ttttccgaaa cggatggcga ggaccgatgc
     5941 tgaaattttc tgcatcatta gaagaattag ttccattttt gtcccaacgc ttaaacgatg
     6001 aggcagagat tgatattatg attgatccag aataaaaaca gaggttgcga caagatgttt
     6061 gtcacaacct ctgtttttta tttcaaataa aattatccaa atacgcggaa gcgatcggca
     6121 tcgttcatgt attctttttc ctcagccggt gtttctggtg aaccgaatac taattgcgaa
     6181 cgtagtttcc agtttgaagg gatattccat tcttttgcaa ctgcttcgtc aataactggg
     6241 ttgtaatgtt gcaagtttgc gcccaatcct ttatcaacta atgctaccca agtattagct
     6301 gttgcgattc cgtttgattg ttctgaccaa tctgggaagt tgtctgcata taattcaaat
     6361 tgttcttgta gaccttttac cacgtcagta tctttgaaga ataatactgt accataacca
     6421 tttttgaaac cagctaattt gttttgtgta tttgggaaag cttctgctgg agtcaatggg
     6481 cgaagtgctt cttcagtgat ttcccaaagt ttttcatgtg catctccgaa aaggataact
     6541 gcgcgtgttg attgagcatt gaaagcagtt gggctttctt taattgcttc tttgatcaaa
     6601 gttgttaatt cttcattaga aagtgaaaca ttacgtccta gatgatagat tgaacggcgg
     6661 tttttcaaag tgtcagtaaa agttgtcata ataaaatttc tcctttgatt tgcgttttgc
     6721 atttttttaa ttgattacga aatgaagtat agcaccttac aaaaagtaag taaacagata
     6781 tgctcacaaa aaataagcga agttcaaaaa acaattttaa taagaaaaat cgttatgtaa
     6841 ggattttct
//
LOCUS       DACGEU010000119         6733 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.123, whole genome shotgun sequence.
ACCESSION   DACGEU010000119 DACGEU010000000
VERSION     DACGEU010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6733)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6733)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6733
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.123"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            <1..546
                     /locus_tag="IXR40_002590"
     CDS             <1..546
                     /locus_tag="IXR40_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAQ4362384.1"
                     /translation="IHRRFYTSICHQKITTDTTEFKYHEVDAKGIIRQKKLYLDPFMD
                     MFNSEILSYRISEKPNALAVMEGLEEAIQTTNDCPYRRTFHSDQGWAYQMKAYRNKLK
                     EYKIFQSMSRKGNCLDNSLMENFFGLLKQEIFHGKVYNCFEELKSAIDSYIYYYNNER
                     IKQKLNWQSPVQFRKTTVTVV"
     gene            complement(716..1678)
                     /locus_tag="IXR40_002591"
     CDS             complement(716..1678)
                     /locus_tag="IXR40_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018375965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAQ4362385.1"
                     /translation="MVAKLTDVAELAGVSPTTVSRVINNKGYLSEKTKQKVHEAMKTL
                     GYKPNNLARGLQGKSPQLIGLIFPNISNIFYSELIEYLEIELFKHGYKTIICNSQNDP
                     AKEREYIEMLEANQVDGIISSSHNLGIADYERVRAPIVAFDRNLAPNVSIVSSDNFEG
                     GKLAAKTLQKNGCQNTIMITGNDNTDSPTELRALGFSFQNPNGKIFKIPNNLSTIRRE
                     MEIKSTIINHKPDGIFVSDDLTAILTMKIAHQLKLNIPEDLKIIGYDGTSFIEKFFPQ
                     LTTIRQPIDEIASLIVDILLKKIKGEKTNKDYILPISILSGGSI"
     gene            complement(1680..3119)
                     /locus_tag="IXR40_002592"
     CDS             complement(1680..3119)
                     /locus_tag="IXR40_002592"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HAQ4362386.1"
                     /translation="MNLPREIRYRAYSDWTKDEMDKIKDNVKRSPWRASYHIEPKTGL
                     LNDPNGFSFFNGKYTLFYQNWPFGAAHGLKEWVHNESDDLVHFHVTGAELLPDTKRDS
                     HGAYSGSAYEIEGNLFLLYTGNVRNENWERDTLQIGAWMDKDYNITKGENVLIHKPAD
                     VTDHFRDPQMFNYEGQLYAIVGAQNLEKSGFIKLYKADDNNVETWEEVGNLDFGGTGS
                     EYMIECPNLVFVDKKPVLIYCPQGLDKSELNYGNIYPNTFKICQSLDIEKVKLVGASE
                     IQNLDYGFEAYATQGFNTPDGRALIVSWIGLPDIDYPTDKYDYQGAMSLVKELSIKDG
                     KLYQYPVEAITSLRASSEQFTAKAETNNTYELELTFPPNQKSELLLFSDSKGNGLSLI
                     VDTKEGKIILDRSKAGIQYATDFGTIRECSIDTKETTANIFVDNSIIEIFINKGEKVF
                     TSRVFPENHQNGIQIKSGEPTGKYFELKY"
     gene            3304..5250
                     /locus_tag="IXR40_002593"
     CDS             3304..5250
                     /locus_tag="IXR40_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HAQ4362387.1"
                     /translation="MNYSKVASDVIQAVGKDNLIAAAHCATRLRLVLKDDTKVNQKAL
                     DENPDVKSTFKIDGQYQVIIGAGDVNFVYDELIKKTGLSEISTDDLKQIASKDKKFNP
                     IMALIKLLSDIFVPIIPALVAGGLLMALQNFLTAAGLFGPKSIEEMYPAIEGISSMIQ
                     LMSAAPFMFLPILVGISAAKRFGANQFLGAAIGMIMTTPDLGGSTEYWNIFGYHVSQT
                     NYAYQVIPVLAAVWILSILEKFFHKKLPSSIDFTFTPLLSVMITGFLTFTVIGPVMLL
                     LSNGITDIIVWLYNTTGFIGMGIFGGTYSLIVMTGLHQSFPAIETQLLSAWTNGIGHG
                     DFIFVVASMANVAQGAATFAIWFLTKNSKTKSLASSAGVSALLGITEPALFGVNLKYR
                     FPFFCALIGSGIATAVAGLLKVVAVSLGSAGFLGFLSINATSIPFYVLCELISFVVAF
                     AITYFYGKTKAAGIFKAEEIAEQTPVNSSKVATTDPISTDVESTQTKVSSETIVSPIS
                     GKVISLSSVNDPVFSSEAMGKGIAIKPNGNTVHSPVDGTIQLTFETGHAYGIKSNNGA
                     EVLIHIGIDTVSMGGKGFTQKVTTNQKVRKGDILGAFDRSMIEKEGLDDTTMIIVTNT
                     SDYSEVNIVAENTVTEGTDLLEIK"
     gene            5514..6386
                     /locus_tag="IXR40_002594"
     CDS             5514..6386
                     /locus_tag="IXR40_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAQ4362388.1"
                     /translation="MLYGAIEAGGTKFVCAIGDEEMTIKERVSFPTTTPEETMPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPKLAWQNFDFIGTMKKEFPIPIS
                     WTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGGGALQEGRFIEGFSHPEMGHMLVV
                     PHPKDDFAGSCPFHGNCLEGMAAGPAIENRLGKKGQEVAEDDPYWEIEASYIAQCAYN
                     TTLMFSPDVIIFGGGVMKQRHMLQNVHDAFAKLVNGYVETPELSKYIVTPALEDNAGT
                     LGCLALAREAVLHS"
BASE COUNT         2163 a         1151 c         1203 g         2216 t
ORIGIN      
        1 atccatcgtc gtttctacac cagtatctgc catcagaaaa tcacgacgga tacaactgaa
       61 tttaaatacc atgaagtgga tgccaaaggc attatccgtc aaaagaaatt gtatctagat
      121 ccttttatgg atatgttcaa tagtgagatt ttatcctatc gtatctctga aaagcccaat
      181 gcattagcgg taatggaagg tttggaggaa gctatccaga ccactaacga ttgtccctat
      241 cgtcgtacgt ttcactcaga tcaaggttgg gcgtatcaaa tgaaagctta tagaaacaaa
      301 ttgaaggagt acaaaatctt tcaaagcatg tctcggaaag ggaactgctt agataattca
      361 cttatggaga atttttttgg cttattaaaa caagagattt ttcacgggaa agtttataac
      421 tgtttcgagg aattaaaatc agccatcgat agctatatct attactacaa taatgaacgg
      481 ataaaacaga aattaaactg gcaaagtccc gtccaatttc gtaaaacaac cgtaacagtt
      541 gtgtaaaaat atcattttag agcatgaaaa aaggagtgga tttctccact ccaaaaaagt
      601 ctaacttttg ggggtcacta caagttgaca actccttttt gtttacaaat caattggata
      661 tctacaaatt gtattttcta acgaatttta tagacattaa aaaattaatt taacgttaaa
      721 tacttcctcc agaaagtatt gagattggta aaatataatc cttatttgtc ttttcgcctt
      781 taattttttt cagaagaata tcaacaataa gacttgcaat ttcatcaatt ggttgtctta
      841 ttgttgtcaa ttgtgggaaa aatttctcaa tgaaagaggt accatcgtat ccaataattt
      901 ttaaatcttc tgggatatta agtttaagtt gatgagcaat tttcatagtg agaatggctg
      961 ttaaatcatc agaaacaaaa ataccatctg gtttgtgatt tataatagtt gactttattt
     1021 ccatttcacg acggatagta gacagattat taggaatttt gaaaattttt ccatttggat
     1081 tttgaaaaga aaaacctagt gcacgtaatt ctgtgggaga atccgtgtta tcatttcctg
     1141 taatcataat ggtattttga caaccatttt tttgtaaagt cttagctgca agttttcccc
     1201 cttcaaagtt atctgaagaa acaatggaaa cattaggagc taaatttcta tcaaaagcaa
     1261 caataggtgc tctcacacgc tcataatcag caattccaag attatggctt gatgagatta
     1321 tgccatcaac ttggttggct tcaagcattt caatgtattc tctctcttta gcaggatcat
     1381 tttgactatt gcaaataatc gttttatatc catgtttaaa taactctatt tcgagatact
     1441 caatgagttc agagtaaaag atattactaa tattaggaaa aataagacca ataagctgag
     1501 gtgactttcc ttgaagtcca cgtgctaaat tatttggttt ataaccaaga gttttcatag
     1561 cttcatgaac tttttgtttt gttttttctg ataaatatcc cttattatta atgacgcgtg
     1621 aaacggttgt tgggctaact ccagctaatt cagcgacatc agttaatttt gctaccattt
     1681 taatatttta attcaaagta ttttccagta ggttcgcctg atttgatttg aataccattt
     1741 tggtgatttt cagggaatac acgactagta aacacttttt ctcctttatt aataaaaatc
     1801 tcaatgattg agttatctac aaaaatgtta gcagttgttt ctttagtatc aattgagcat
     1861 tcacgaatcg taccaaagtc agtggcatat tgaatgcctg ctttgctgcg atctaaaata
     1921 atttttcctt ctttggtatc tacaatcaag ctaagtccat ttcctttact atcagagaaa
     1981 agaagtaact ccgatttctg atttggagga aaagttagtt caagctcata agtattattt
     2041 gtttctgctt ttgctgtaaa ttgttcagaa ctagcacgta atgatgtaat agcttctact
     2101 ggatattggt aaagtttacc atcttttatt gaaagttctt ttacaagact cattgctccc
     2161 tgataatcat acttatcagt tggataatcg atatcaggta gtccaatcca actgacaatc
     2221 agagcacgac catcaggagt attgaatcct tgagtcgcat acgcttcaaa tccataatca
     2281 agattttgaa tttctgaagc gcccacaagt tttacttttt ctatgtcaag cgattgacag
     2341 atcttaaaag tattcggata gatattccca taatttagct cagatttatc caacccttga
     2401 ggacaataaa tgagaacagg ttttttgtct acaaatacta gatttggaca ctcaatcatg
     2461 tattctgaac cagtgccgcc aaaatcaagg ttgccaactt cctcccatgt ttccacgtta
     2521 ttgtcatccg ctttgtaaag tttgataaag cctgattttt ctaaattttg tgctccaaca
     2581 atcgcataca attgtccttc ataattaaac atttgtggat cacgaaaatg atcagttaca
     2641 tcagcaggtt tatgaataag aacattctca cctttcgtaa tgttgtagtc tttatccatc
     2701 catgctccga tttgaagtgt atcacgttcc caattttcat ttcgaacgtt tcctgtatag
     2761 agtaagaata gattcccctc tatttcatat gcagaaccgg aataagcgcc gtggctatct
     2821 cgttttgtgt ctggaagaag ttctgctcct gttacatgaa aatgaactaa atcatctgat
     2881 tcattgtgta cccattcttt caacccatga gcagctccaa atggccaatt ttgataaaaa
     2941 agcgtatatt ttccgttaaa aaaagaaaaa ccattaggat cgtttaacaa tcctgtttta
     3001 ggttcgatat gatagctagc acgccaaggt gatcgtttta cattatcctt aattttatcc
     3061 atctcatctt tagtccaatc agaataagca cgatatcgta tttctcgagg taagttcata
     3121 ttttactcct tcaatttatc tttttacaac tagtatggta aacgttttcc gttgaaaaat
     3181 caatcatttc atttaaaaaa ataaactata tgacaaacgt ttgacatatt tttaagatat
     3241 gctaaaataa atttgcattt cagtgaaccg ttttcacgta aaaataaaaa aggagtgatt
     3301 cgaatgaatt acagtaaagt agcttccgac gtaatacaag cggtcggaaa agataacctt
     3361 attgcagctg cacactgcgc tacacgtctt cgtctcgtac taaaagatga cacgaaagtg
     3421 aatcaaaaag ctttagacga aaatccagat gtgaaaagca catttaaaat tgatggacaa
     3481 tatcaagtga ttatcggtgc aggtgatgtt aatttcgttt atgacgaact tatcaaaaaa
     3541 actggacttt cggaaatttc aacagatgat ttaaaacaaa ttgctagtaa agataaaaaa
     3601 ttcaacccca ttatggcatt aattaaatta ttatcagata tttttgttcc aattatacct
     3661 gcccttgttg caggtggttt attaatggca ttacaaaact ttttaacagc tgctggactt
     3721 tttggaccaa aatcaattga agaaatgtat cctgcgattg aaggtatttc ctcaatgatc
     3781 caactgatgt ccgctgcacc attcatgttc ttaccaattt tagtaggtat ttcagctgct
     3841 aaacgttttg gagcaaacca atttcttggt gctgcaattg gtatgatcat gacaacacca
     3901 gatcttggtg gctcaactga atattggaat atttttggtt atcatgtttc acaaacaaac
     3961 tatgcttatc aagttattcc agttttagca gctgtttgga tattatctat attagaaaaa
     4021 ttctttcata aaaaattgcc atcatctatt gactttacat tcacgccatt attatcagta
     4081 atgattactg gatttttgac tttcacagtt attggccctg taatgttatt gttgtctaat
     4141 ggaattacag acattattgt ttggctatat aacactactg gatttattgg aatgggtatt
     4201 tttggaggaa catattcact tatagtcatg actggtttac atcaatcatt tccagctatt
     4261 gaaactcaat tactttcagc gtggacaaat ggtatcggac atggagactt tatctttgta
     4321 gttgcatcta tggcaaacgt tgctcaaggt gctgcaacat ttgccatttg gttcttaact
     4381 aaaaattcta agacaaaaag tcttgcttcc tctgcgggtg tctcagcact tcttggaatt
     4441 acagagcctg ccttgttcgg agttaactta aaataccgct ttccattctt ttgtgcttta
     4501 attggttcag gaattgctac agcagtagca ggattactta aagtagttgc tgtttcactt
     4561 ggttcagcag gtttcttggg atttctttca attaatgcaa catctattcc attttacgta
     4621 ttgtgtgaat tgattagctt tgtagttgct tttgcaatta cttacttcta cggtaaaaca
     4681 aaagctgctg gtatctttaa agcagaagaa attgctgaac aaacaccagt taattcttca
     4741 aaagtagcaa caacagatcc aatatctact gatgttgaat caacacaaac aaaagtttca
     4801 tcagaaacaa ttgttagtcc catttctggt aaagtgatta gtctttcttc agtaaatgat
     4861 ccagtctttt catcagaagc tatgggaaaa gggattgcca ttaaaccaaa tggaaacacg
     4921 gtccattctc cagtagatgg tactattcaa ctcacgtttg aaactggaca tgcttatggt
     4981 attaaatcaa ataatggtgc tgaagttcta attcatattg gtattgatac tgtatcaatg
     5041 ggaggaaaag gatttacaca aaaagttact actaatcaaa aagttagaaa aggcgatatt
     5101 cttggagcat ttgaccgttc aatgattgag aaagaaggtc ttgatgatac aacaatgatt
     5161 attgtgacca atacttcgga ttattcagaa gtaaatatag tagctgaaaa tacagtcact
     5221 gagggtactg atttacttga aatcaaataa atatatttcc ctgagtaaag atggaatttt
     5281 ctttccaaaa tcaaataata tagattaatc aaatatttga gaataacatt ttatttaatc
     5341 ttttcatata tcaattgtat gaaaaattat tagaatttta aaaaatgata aaaattcaaa
     5401 aagaaaaaat agtagttatt tacttgtcat gttactaaat aaaaaaataa tttaaatatg
     5461 atatatagtc atttatttag tgatttcatt ctaaaataaa gggagaaatg tctatgctat
     5521 acggtgcaat tgaagcaggc ggcacaaaat ttgtgtgtgc cattggcgat gaagaaatga
     5581 cgatcaagga aagagtgagc tttccgacaa cgacacctga ggaaacaatg cctttagtca
     5641 ttgacttctt caaacaatac caagcagatt tagcagggat tgggattggc tcatttgggc
     5701 ctatcgatat ccatcgcgat tccgccactt atgggtacat tacctcgacc ccgaaattgg
     5761 catggcaaaa ttttgatttc atcggtacca tgaaaaaaga atttccgatc ccgatttctt
     5821 ggacaacaga tgtcaatgcg gctgcctatg gtgagtatgt cttcggcagt ggcaaaggat
     5881 tgagcagtgt cgtttactat acgatcggta cgggtgttgg cggcggtgcc ttacaagaag
     5941 ggcgctttat cgaagggttt agtcatccag aaatggggca tatgctcgtc gtccctcatc
     6001 caaaagatga ctttgctggc agctgtccat ttcatggcaa ctgtttagaa gggatggccg
     6061 ctggacccgc catcgaaaac cgcttaggga aaaaaggaca agaggttgca gaagatgatc
     6121 cttattggga aatcgaagcc tcctatattg ctcaatgtgc ctacaataca accttgatgt
     6181 tttctccaga tgtgatcatt tttggcggtg gtgtgatgaa acaacgccat atgctgcaaa
     6241 acgtccacga cgcatttgca aaattggtca atgggtatgt cgaaacacct gagttaagca
     6301 aatatatcgt gaccccagca ttagaagaca acgctggaac gctcggttgt ttggcattgg
     6361 ctcgagaagc ggtcttacat tcataaacga aaaaaggctc ttcgacattt agtgttggta
     6421 gagaaagata caactgaaaa tttagtcata accagttagg cagagtgctt aactggtttt
     6481 tgttttactt ggaagatcaa gccttgaatg agataaattc ttgctcgaaa gttatggaaa
     6541 tttcgatagc cgtaggccac ttgtattgtg caatagtttt ttacaaaaaa aagggggtgc
     6601 ggatattttt ttggaccttt ttaacaaata ggttctgttg caaagtttta aatctactat
     6661 cagataaggt agaataatag aaaaagatag caggaggaat gacgatgagt cattttaaag
     6721 gaaagcaatt tca
//
LOCUS       DACGEU010000120         6387 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.124, whole genome shotgun sequence.
ACCESSION   DACGEU010000120 DACGEU010000000
VERSION     DACGEU010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6387)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6387)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6387
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.124"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            330..1175
                     /locus_tag="IXR40_002595"
     CDS             330..1175
                     /locus_tag="IXR40_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAQ4362389.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
     gene            1456..2676
                     /locus_tag="IXR40_002596"
     CDS             1456..2676
                     /locus_tag="IXR40_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair exonuclease"
                     /protein_id="HAQ4362390.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2673..5393
                     /locus_tag="IXR40_002597"
     CDS             2673..5393
                     /locus_tag="IXR40_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAQ4362391.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            5377..6321
                     /locus_tag="IXR40_002598"
     CDS             5377..6321
                     /locus_tag="IXR40_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAQ4362392.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
BASE COUNT         2379 a          987 c         1231 g         1790 t
ORIGIN      
        1 aaggcaaaaa gatgaactag aaatagttca tctttttttg tttaaatctt ttgctaagtt
       61 gaactaatag agtcttttat gaatatcgaa gttagttttt cacctaactt cgttttttat
      121 agttggttat tataaaatag taatatagct gatttggatt caattcatat ttatttataa
      181 atcaaaaata cagagaatag tatataaatg tcctttccta ttcttaaaat gatgtttgta
      241 cttacttaaa ttaggtataa ttagtatatg ttttgtgaga aatttagact tacaataagc
      301 agtgaattta taatcaacgt ataggagaca tggatgaaat gaaactaatt ggtatagatt
      361 tagacggtac tcttttgaat tctgaccaga gcattagtca aaaaaatgca agaacaatga
      421 aacatttacc ggaagactgt tttccattca tttgttctgg aagagaagta gaagacatta
      481 ataatattct caaaaaatct ggtttaagga taccagcagt agggttaaat ggttctgttg
      541 gatttgatgg agaaaaaaag atatttgagt cttccttcga taaaaatgat gtaaaaaaaa
      601 ttgattctgt cctatcgaaa tttccaacca aaatatatac aaatctcgga agttatgaat
      661 ctcagaatta taaaaataaa atgaaaaaaa tttttcacga ggtagggagt gaattttcta
      721 tcaaagagct aaactatgag cttgagtatg aaaaatctat ttgttcaatc ccttataata
      781 atattgagga aattatagaa aaggatgcta tcagcattta caaatttttt atttttattc
      841 ctaatcgtca attgaaagct aatatattta accatttgaa aaagatgcta aatgtgtctg
      901 ttactgaatc ggcacctgta aatattgaaa tcgtacctca aaatgtatct aaaggtgtgg
      961 tgtttgatcg tttggaatca atctacaatt taaagaaacc tttgagaatc gcgatcggag
     1021 atagtttaaa tgacttatct atgtttgaaa gtgcagatat tagttttgca atgggaaata
     1081 gtcatcaaga aatcatgaaa aaagctgatt atgtcactgt ttcaaatgat aaagacggag
     1141 tatctcaagc atttgaaaga attcttacca tataaactaa ttaaggtagt atagaacata
     1201 gaattctaaa tacggaaaaa tggagcataa attccagtac aaatagtact tcttcagtgt
     1261 caaacgaagc gaatataaca tagatattta ggattgtgac aaaaatcatg tcacaatctt
     1321 tttttcgaat aaacttattt tttgaagtcg gccatttatc gtaatttctt tgcataatac
     1381 gaacaaattt tcggttattg atgaaaaaaa acattgaaaa tggtatgata aaagaaaaaa
     1441 aggaggaaat ttttaatggt gaaatttatc catgcggcag atttacatat ggatcggtca
     1501 tttgaaggac tgacaactct tgataaaact gtacaggaaa aactattgaa gacgaatctg
     1561 accgttttat caaatatcat tgaacaggca ataataaata acgttgattt tgttttactt
     1621 gcaggagata attttcatca aaatcgtcct tcattaaaaa tacagaaaca tttttcagaa
     1681 cagatgaaac ggttagaaaa gaaccatata cctgtattta taatattcgg aaatcatgat
     1741 ttctatcaaa aagagcggta ttggttctcc tttcctaaaa atgtccattt atttacatcc
     1801 gaaacggtag agacaaaaaa aataacgata aaaagtggag aaactgtctc tctcagtgga
     1861 tttagttatc gtcaaccgtg gattcaaaaa gacaaagtga tggaatttcc ttctagagaa
     1921 ctcacagatt accatattgg gttgtaccac ggggaacctg gcgtctctca aaaaggaaac
     1981 tatgctcctt tccaaccctc aaagatgcaa gaaaagggat acgattattg ggctttaggg
     2041 catatccatg tgccaacggt cttaaatgaa aagcaaacaa ttgtttatcc aggtgcgcct
     2101 caaggtcata ctaaaaagga acaagcttct acatctattc tactagttga attaagtaaa
     2161 ggaagttgcc aaatacatcc gattaaagta gcagaggtct attggaagac aaaggaaata
     2221 tcattgagga aagcaagaac gacaaaagag gtcattgttc acattcgtca gcagctttca
     2281 aaagtagagg atggatttag tttaattgag ataaaattaa aagattatga ccatctcaat
     2341 acagatgttt tggaacggat acaatcagga gagctattag actatttgtt agaggaattc
     2401 tcagatagga taaatgattt ctttatttgg cgtatttctc tcatagagaa tactttttat
     2461 acgaagaccc cacttgctgc ttctgctaaa ttgatggaac agttatttca atactatcag
     2521 acacctcaag atttccaaca aattttaaat gaagtatata gtcatcaaga agcggctaga
     2581 atattgagcg aactgccgga atatcaagaa gaaacacttg aaaaagccaa gcagctgctt
     2641 aatcaagatt ttttatttga ggaggatcag gaatgaagat tttaaggatc gagattgctg
     2701 cttttggaaa atggcgtcaa aaaagttttg acttttattc aggcaatcag ctgatctatg
     2761 ggggaaacga agcaggaaaa tcaacgattt atcaatttat tcaagcaata ttatttggtt
     2821 tcccttcaaa aggccgtaaa aaaaaggatt atacaccaaa agacggctca gcctatggcg
     2881 gcaaaatatg gcttaaacat cctgtatatg gtgaatttgc tgtcgagcgc tacaagcagc
     2941 aaaatcgcgg aaaatcgaag gtgtggctgg gggatcaagt gggaagtgat gagttactag
     3001 aaaaactgat cgcacctttg acgaaagagt tattccagca ggtatttact ttccagcaag
     3061 agcagttgat ggaactagat catttgagag aaaaagagct acatgatgcg ctgatttctt
     3121 taggcatcac gggcagttct caagtattcc aaaagcggca agaatattat cagaaagcac
     3181 aacaattatt caagaaaaaa ggccaaaaat tactaatcaa tcaaaaatta aatgaatgga
     3241 aagagctgca agaaaaaatt catcaaaaac aagaacagga agcttatttt ggcaagttga
     3301 tccaacaaga acaggaatac gagtcgcaac agcagcagtt attggcacaa ttaaaagagg
     3361 cgaacaaaca attttcatta gccagacagc aagaacttaa tttttcttta tatgaagaat
     3421 ggcaatctct caaaaaaaac agcactacag gtcttcctga tgagcaactt cttttagatc
     3481 tggagtcttt ctccaaacgg tatcagcaaa caaatgagcg tttggaagaa ttagaagcaa
     3541 cactggaaaa gcatagcggg atggatcagc agtcagccag atattatttt tatttagagc
     3601 aggagcagga actaaaagat ctccagcaac ttcaatttac agcggaacaa ttaaacgaag
     3661 aatggcaaag attacaaatt gagactagag aaacaaattc agaattgaag attttggaac
     3721 aaaggtggca ttggcagaaa aatccgttac cggaagaatt tttatatgaa gaagaatgga
     3781 agcatcttct ggctgaagaa agaaggattg ctgatctaga aagccagatt tctgtgcgtc
     3841 tccaaatagc taaagaacag caagagatga ttgaagcaga agtgaatgac ttggaagaga
     3901 cctatccagc attattacaa aatcagtcag agatagcacc agtctcttca tctaaaccgt
     3961 atatgctgat ggctggcgga gcaataatca ttgcaggtat atttgtacca atgcccttga
     4021 aagtgatcct tttactaatt ggtgcaggca tgattggcta tttcttctac aaaaggcaac
     4081 caaaaattaa aactaaaaat gatttctctg agataaaagg aatgtggcaa gaaaaactag
     4141 gacaacttga tctagcctta gctcaattag ctgaagcaga agaaaaacaa aagagaactg
     4201 gagaagaaaa acagattctt cagcaagaag tatatcgttt tgcggatcat cggcacttag
     4261 gaaagatgga tacgctcaaa ctcatgaaag aatatggaca ggaagtcata gattatcaga
     4321 aattatatgg cgtatttgag cggaaacata aaagagaaca ggaaatacaa gaaaaactac
     4381 gacaaatcga ccaaaaattt gagtttgtta aagaatggtt accgatacaa gataagacaa
     4441 tttcagaaaa aatggtattg ctttcccgtt ttatacaaga gatggaacag atgaaatttg
     4501 ccagaagcta tcagcaaaat actttattga agcaagaaat caatcaattg aaaaagaaac
     4561 aaaaagtatg gatacaagaa tacagcgaac aattgactca agcaggctta tcttatcctt
     4621 cggaagtacc tgtcttttta caaaaagcca aacaagccga acagcagatg aaaagataca
     4681 atgaattatc ggaaatgctt actccactat ttcctgaaga gctgacaaaa gagaaattat
     4741 ctgtaagact gcgccaactg aaagaaaagc aatcccaact ccagcaagaa gaaaaagaag
     4801 caagtgaaaa tcggcaacga ctccaacttc aagtagaaga gttgcaaaga gacggcacat
     4861 tggacgaact ttatcaacaa gctagccggc aaaaagcaaa attacaggaa ttactggagg
     4921 aatggggagc acttgaaatc gccgggacat tcttaggtga tctttcaaca gagatgagtg
     4981 aaagacaatt accccagttg ttaagagcag caggtgatta tttaggtatt ttaacaaaag
     5041 gaaattatca gaagatatta ctgaaaaatg atacactgac tttaacagac ggatatacag
     5101 aatttcccat ctatgagtta tctacaggta cgaaagatca gctgattatg gcgatgagat
     5161 ttgcttacct ctcattagaa gctaaccgtt cgatatgccc gatcatcatt gatgatggct
     5221 ggcttcatta tgatcatcag cgaaagtatc aattagctga acttttagct aaatttggag
     5281 aaaagtatca aataatttgt ttttcttctg ataaagaaat ggtaagctat taccatgaga
     5341 tgaaccaaat cgtaaaacaa ttagaaggag caaataatga aaaaaattcg tgatttagta
     5401 atcgatgagc agtttgaaca atttgtcctg atcaaaagtg cagatgtaag aatcgctaaa
     5461 aacggaaaaa aatttattgc ttttactttc caagatactt caggtactat cgatggtaaa
     5521 tactgggatg cttcggagga ggaaatcaat aaatttacag ccggcacagt cgtttttcta
     5581 aacggtaaaa gagaggttta tcaaggaaac cctcaagtaa agattcttca tatgcgctta
     5641 acaagggtag atgagccagg agagcctagt ttatacatgg aaagagcccc tttgaagaaa
     5701 gaagaaatgg aagaagaaat caatcaattg ttgtttgaga tcaccaatgc gcattggaat
     5761 cgtattgttc gctatctact taataaatat caaaaacaat tttttgagtt tccggcagca
     5821 aaaagaaacc atcatgcatt tgccagtgga ttagcttatc atactttgac aatgcttcac
     5881 ttagggaaat caatcgccga tgaatatcct gagctgaatc gagcattgtt gtatgctggt
     5941 atcattttgc atgatttagg aaaggtgatt gaactttccg gtcctatgtc gacagaatat
     6001 acgcttgcag gaaatttgat cggtcatctg gtattgattg acgaagaaat aactaaagcc
     6061 tgtcttgcgt tgaaaatcag cgaagctgac gaagatgttc tcgtattacg tcatatggtt
     6121 ttagcacacc atggcttatt agaatatggc tcacctgtac gtccaagaat aatggaagca
     6181 gaaatattac atcaaatcga caatatcgat gcttcgatgc agatgatgtt gacttcgatt
     6241 cgtcaaacag aaccaggaaa atacaccgat cggattttcg gtatggacaa ccgaagtttc
     6301 tatgtaccaa aagatttata gcaaaaattt atttttttca ttcaaaacaa aaaaagcgag
     6361 acataagtct tcgctttttt tgttttc
//
LOCUS       DACGEU010000121         6148 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.125, whole genome shotgun sequence.
ACCESSION   DACGEU010000121 DACGEU010000000
VERSION     DACGEU010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6148)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6148)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6148
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.125"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            <1..566
                     /locus_tag="IXR40_002599"
     CDS             <1..566
                     /locus_tag="IXR40_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HAQ4362393.1"
                     /translation="YFKSEKDTSSLTLTLEEGVEPDKVTSKVINQLKEKGSLKHLGEY
                     EVLDTAMLTKGIGQILSTITYFITAVAGISLFIAGVGVMNMMYISVSERTKEIGIRRA
                     LGATRKSIMLQFLLEGLILTLSGGLIGYLLGMALAYSVGSLIKVNVSLDLFTILLAVG
                     VSSVIGLVFSVMPASEAAKKDLIDILR"
     gene            967..1572
                     /locus_tag="IXR40_002600"
     CDS             967..1572
                     /locus_tag="IXR40_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell filamentation protein"
                     /protein_id="HAQ4362394.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTF
                     KGLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEII
                     KKYVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDL
                     EIRYLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
     gene            1588..2160
                     /locus_tag="IXR40_002601"
     CDS             1588..2160
                     /locus_tag="IXR40_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAQ4362395.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGTKRD
                     RPKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTS
                     MGRMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELL
                     TSGKSYKEVEAITGFSRSTLFRIKKKIEES"
     gene            complement(2412..2669)
                     /locus_tag="IXR40_002602"
     CDS             complement(2412..2669)
                     /locus_tag="IXR40_002602"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362396.1"
                     /translation="MANLYIENKGDLNAIITLIVVMVKSIGNITIGMLFIILAAVLIF
                     MIVIWFLNERSKDNQHRRDMEIKSIESIDYLSIITLKKPRS"
     gene            complement(2795..3610)
                     /locus_tag="IXR40_002603"
     CDS             complement(2795..3610)
                     /locus_tag="IXR40_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362397.1"
                     /translation="MVKIAGLSKGGKTVSQLYKQNYRDWRQFRKNIKDSYFILPTELE
                     KYLPNNKAINLYLYYCFKAKNEGGDSWHSVNTIAESLGVTTKTINTWNKTLVDLGMIA
                     RIDDNHLSKSTILLPLSSYYKLALDSSLKDVTESTVHEIDGNLVAVYHLFEWRKNEAD
                     ENYNVPYNTLCCVFKRKTQKDTIYKFILVQDEKISNFELSTPSSKIYDDAYRFECQDL
                     EALLSANNLNNIEHENFVVNTRFNLVSEKDSDLLDLLIELTKNLDKKENITVL"
     gene            4127..5452
                     /locus_tag="IXR40_002604"
     CDS             4127..5452
                     /locus_tag="IXR40_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HAQ4362398.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPAAKKKYGISNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSMNLFTTEGTRSQRRKKLAQMIQENIKEELGLLA
                     TVGVGDNPLLAKLALDNEAKHNDGFLAEWTYQNVPDKVWNIPEMTDLWGIGSRMKKRL
                     NQIGIMSIKDLANWNPYTIKSHLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLYIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGAGGLKND"
     gene            5445..5795
                     /locus_tag="IXR40_002605"
     CDS             5445..5795
                     /locus_tag="IXR40_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362399.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEKIDADNEQRANQNLAKEQMTTE
                     EVAEVLNAAVIKNRSVCIQKEERNAEGYYPEDIVSKILGSDELGIYVGKNKVHYDEIR
                     HIEFYQDNKWGRLE"
BASE COUNT         2110 a          929 c         1169 g         1940 t
ORIGIN      
        1 attattttaa gtctgaaaag gatacatcgt ctctaacgtt aactttagag gaaggagttg
       61 aacctgacaa ggtgacctct aaagtgataa accaattgaa agaaaaaggt agtttgaaac
      121 atttggggga atatgaagtg ttagatacgg ctatgttaac gaaaggaatt ggtcaaatcc
      181 tcagtacgat cacttatttt ataacagctg tagcaggtat atctttattt atcgcagggg
      241 taggtgtaat gaacatgatg tatatatctg tatctgaacg aacaaaagag atcggtataa
      301 gaagagccct aggagctact cgaaaatcga ttatgctgca gttcctttta gaaggtttga
      361 ttttaactct ttcaggaggg ttaattggct atttattagg aatggctctt gcttatagtg
      421 ttggttcttt gataaaggta aacgtgtcac ttgatctatt tactatttta ctagcggttg
      481 gggtatcttc ggttattgga ctggtctttt ctgtaatgcc cgcttcagag gctgcaaaaa
      541 aagatttaat tgatattctt agataaaatc agaatgacaa gaatatttac gttctagatt
      601 ctaaaataaa acacaaagag accaaccagg caccctattg tttctttgta gtatagagat
      661 attctttggc ttgtaagaga tcaatagagt taggtgaccg gagttcgaaa taaaggaaat
      721 ttttgattgt ataggagaat tctttatccc taatatttag aattttgagt atgccatgtt
      781 gatgttttag attctctata aatatagagg tgtatcaaag gtcaactaga ctgtgcaaaa
      841 tagagacact tgaaaaatct atcgggggtc agaaacttaa tagtttttga cacataaaca
      901 aaatcgcgat ataatggggt tgagagtgtt tcataaactt atgtcataaa gttaaggaga
      961 tttcgcatga ttttagagaa taaattggga ttaaccaatc aagttgagtt ggctaaggtt
     1021 gaagaaaaac tcagtaaaca aaaagcgaaa gaattgtacg attgtggaaa aataaatgaa
     1081 atcgaagttg gtacatttaa aggtttatct gaaattcatg aatttctatt ttcggatatt
     1141 tacgattttg ccggaaaaat ccgatcggtc aatattgcaa aaggaaattt tcgatttgca
     1201 ccagttatgt atttagaaca ttcgttacag catattgatc agatgccaca aacttctttt
     1261 gaagagatta tcaagaaata tgtggagatg aatatcgctc acccatttcg agaaggaaat
     1321 ggccgaagta ctagaatttg gctggatctc attttaaagg aagaattgca aaaagttgta
     1381 gattggaact taatcgataa agcagactat ctttctgcaa tggagcgaag tcccataaac
     1441 gatttggaaa tacgctatct aatttccaat gctctgactg ataaaattga cgatcgcgag
     1501 ttatatatga aaggaatcga tgtcagctat ttctatgaag ggtattctga gtatacgata
     1561 gatgatttgt aaaagtaggt ggaccaaatg acgaaatatg gatatgcacg tgtctcaacc
     1621 gcttctcaaa gtacaaaaga acaaattcaa cagttgcttg agaacggcgt agagaagaag
     1681 aatatttttt cagaaaaatt tacgggtaca aaacgggatc ggccaaaatt caatcagctg
     1741 ttggctggtc tgaagcctgg agatgaaata gttgttacga agcttgatcg atttgctcgt
     1801 aacacgagag aagcattaga gatcattgaa cctttactcg atgataacgt aacgatcaag
     1861 gttttgaatc taggaacgat tgaaaatacg tccatggggc gaatggtgac acggacgttg
     1921 ttgagtgtag cagaaatgga acgtgatatg attgtggaac gtacccaaga aggaaaaatg
     1981 tttgcaagaa agaataatcc taatttcaga gaaggacgtc cgaaagcaac aatcacaccg
     2041 aagaagaggc acgcatatga actgcttact tcaggtaaat cgtataagga agttgaagct
     2101 ataaccggtt tcagtcgcag tacgcttttt agaataaaga agaaaattga agaaagttaa
     2161 aaaagaagtc tcagcgaacc agacaggtaa atacttaatg cgttctagat atgagtctat
     2221 tagcatgttg tgaaatataa tattttttta tttacttgat ttctgctcaa aaaatgtgta
     2281 tggtaactgt aaaaggtaaa gtaattaaag gtatgctagc cacgcttact atattaggat
     2341 accatcatat atttataatg aacgatttgt tcgtctacca aacaacacat atcgttcagc
     2401 gtaagtcacg tttaggaacg tggctttttt agtgttatta tcgataaata atctattgac
     2461 tctattgatt ttatctccat atccctacgg tgttgattgt ctttagatct ttcatttaag
     2521 aaccaaataa ctatcataaa aatcagcact gctgctaata taataaacag cattcctatt
     2581 gtgatattac ctattgattt taccataact acgattaaag taataatggc attcaagtct
     2641 cctttgttct ctatatataa attagccata aatcatcttc ctttcaaatt aagatacttg
     2701 tttgatacca ataaatagta agcgtggcta gcataccttt ttctgtaata gcaagtgttc
     2761 taatagtcca aacttaatga tggaccgatg ctagttatag tacagtaatg ttttctttct
     2821 tatctagatt tttagtaagc tctatcagca aatctaacaa atctgagtcc ttttcagaaa
     2881 ctaaattaaa tctagtgttt acaacaaagt tttcatgttc tatattgttt agattatttg
     2941 cggaaaggag ggcttctaga tcttgacatt caaatctata tgcatcgtca taaatcttac
     3001 tagaaggagt gcttaattcg aaattactta ttttctcatc ttggaccaag ataaatttat
     3061 agatagtatc tttttgtgtt tttcttttaa aaacacaaca gagtgtgtta taaggaacgt
     3121 tataattttc atcagcctca ttttttctcc attcaaacaa atgataaact gcaaccaagt
     3181 tgccatcaat ttcatggaca gtgctctcgg taacatcctt taaagaacta tcaagggcta
     3241 atttatagta actagagaga ggaagtaaaa ttgtcgattt actgagatgg ttatcgtcta
     3301 tacgtgcaat catacctaaa tcaactaagg ttttattcca ggtgtttata gttttagttg
     3361 tcactcctag agactctgct atggtattga ccgaatgcca ggaatccccg ccttcattct
     3421 ttgccttaaa acagtaatac agatataaat taatagcttt gttattcggt aaatattttt
     3481 caagttctgt tggtagaata aagtaagaat ccttaatgtt ttttctgaac tgtctccagt
     3541 ctctgtagtt ttgtttataa agttgtgaaa cggtttttcc acctttagaa agtcctgcta
     3601 tcttaaccaa tcttattgct cctttcttga atctgtcatg atcatacagt attttttact
     3661 tgtagtccag caccttaata tattatccta tgtaattaat ttcgtactag atagtaatta
     3721 ttttttattt aattctctag tcacttacaa ataagttata taaactacga ttaataaatt
     3781 attacaaaaa ctattaagaa aacttctaca tacaactatt acaaaactat taagaaactg
     3841 aatactccta ttttttgttt ttaaggaaag ttttttcttt tttgaatttc ttattttttt
     3901 ctaatataac taagcaaaac tggataatac gacacttatt ttcaaatttt cacaagacta
     3961 atagtaaata tccatttaat aaagtgatac aatgtgttga ttttacaaat caacagaaga
     4021 agtagggaaa taacttacct atgcttcttt ttttgtacat ttaatcgatt cttctttaca
     4081 aaaacgaacg tatgtttgta taatgtggaa gaatggagtg ttatttatga tggattattc
     4141 aaaagagcca gtaaatgatt actttttgat cgatatgaaa agcttttacg caagtgtcga
     4201 atgtatagaa aggaatttag atccattaac gactgaatta gtcgtcatga gtcgagcgga
     4261 taatacagga tcagggttga ttttagcttc ttcaccagct gcaaagaaga agtacggtat
     4321 ttctaatgtc agtcgaccac gagatctacc gcaacctttt cctaaaacgt tacatgtcgt
     4381 tccaccacgc atgaatctct atattaagcg aaatatgcag gtaaacaata ttttcagaag
     4441 gtatgtagca gacgaagatt tattgattta ctcgatcgat gaatcgatct taaaagtgac
     4501 cagatcaatg aatcttttta cgactgaagg aacaagaagt caacggagaa agaagctggc
     4561 tcaaatgatc caggagaata ttaaagaaga gctaggattg cttgctacag taggtgtcgg
     4621 agataatccc ttattagcta aacttgcttt agacaatgaa gcaaaacata atgatggatt
     4681 ccttgctgaa tggacgtatc aaaatgttcc tgataaagta tggaatattc ctgaaatgac
     4741 agacctttgg ggtattggat ctcgaatgaa aaaaagactc aaccaaattg gtatcatgag
     4801 tattaaagac ttagctaatt ggaatccata cactattaag agccatttag gtgtgattgg
     4861 cttacagctg tattttcatg cgaacgggat cgatcgaaca gatatagcga tcccaccaga
     4921 accgacaaag gaaaaatcat atggtaattc acaagtgtta ccacgagatt ataccaggag
     4981 aaatgaaatc gaactggtgg taaaagaaat ggcggaacaa gtagctattc gtatcaggca
     5041 acataactgt aaaacaggtt gtgtccattt atacattggc acgtcgatct tagaaacgag
     5101 accaggtttt tcacaccaga tgaagatccc tataacagat aatacaaagg aattgcagaa
     5161 ttactgtctt ttcttgtttg ataagtatta tgaaggacaa gaagtaaggc acgttggaat
     5221 aacctatagc aagcttgtgt acactgattc gcttcagctg gatttattta gtgatccaca
     5281 aaagcaaatt gacgaagaaa atttagataa aattattgac aagattcggc aaaaatatgg
     5341 ttttacgtcg attgtacatg cttcttctat gttagaaggc gctcgtagta ttactagaag
     5401 tacattggtt ggtggccatg caggcggcgc aggagggctt aaaaatgatt gattataatg
     5461 atcgtggacg tttaaagtgg gcaggttttt atttatctga tcatactgaa aaaattgatg
     5521 ccgacaatga acaacgagcc aatcaaaatt tggcaaaaga acaaatgacg actgaagagg
     5581 ttgcggaagt attgaacgct gcagtcataa aaaatagatc agtatgtatt caaaaagaag
     5641 aacgaaacgc tgaaggatac tatccagaag atattgttag caagatctta ggtagtgatg
     5701 agctggggat ctacgttgga aaaaacaaag ttcactacga cgaaatacgt catatcgaat
     5761 tttaccagga taataaatgg ggtcgattag aatgaacatt atccagcaat atgagctaaa
     5821 gtatataacc tttgatcagc tatcagaaga gatttggggt tatggccagc gtttgataaa
     5881 tgaggttggt gttgaacgct tctctttcta tgtagaagct gcagcaggat accataaata
     5941 cgaatactat attggctatt aaagtgcaat aaaattatat ttcttttatg ttttacattt
     6001 tgtatcaatt ctgataaaat tacctatagg taattaaaaa atataaaaaa actagttaca
     6061 accttaggac gttgtaacta gcttgaagca tactagagct aactaaaata gcactagaaa
     6121 gcaatgttaa acccgtccaa caaacttg
//
LOCUS       DACGEU010000122         6070 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.127, whole genome shotgun sequence.
ACCESSION   DACGEU010000122 DACGEU010000000
VERSION     DACGEU010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6070)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6070)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6070
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.127"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(282..767)
                     /locus_tag="IXR40_002606"
     CDS             complement(282..767)
                     /locus_tag="IXR40_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362400.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(906..1121)
                     /locus_tag="IXR40_002607"
     CDS             complement(906..1121)
                     /locus_tag="IXR40_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HAQ4362401.1"
                     /translation="MKTLDAIALTLLIVGGLNWLLVGLFELDLVAMIAGGSTTIFAKI
                     IYIVVGICAIYCLKFFPMITRKVDERY"
     gene            1345..2145
                     /locus_tag="IXR40_002608"
     CDS             1345..2145
                     /locus_tag="IXR40_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAQ4362402.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            2164..4032
                     /locus_tag="IXR40_002609"
     CDS             2164..4032
                     /locus_tag="IXR40_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAQ4362403.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            4025..4516
                     /locus_tag="IXR40_002610"
     CDS             4025..4516
                     /locus_tag="IXR40_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HAQ4362404.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            4504..5058
                     /gene="srlA"
                     /locus_tag="IXR40_002611"
     CDS             4504..5058
                     /gene="srlA"
                     /locus_tag="IXR40_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174078.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HAQ4362405.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            5076..>6070
                     /locus_tag="IXR40_002612"
     CDS             5076..>6070
                     /locus_tag="IXR40_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HAQ4362406.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVSTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         2139 a          967 c         1217 g         1747 t
ORIGIN      
        1 tcaaaaggta aaaaagtaaa ttcttctatc caaatataga aaaattgaat ctagaaaacc
       61 gcccgacaat aaatttcatt aactcagttg accgaaaatg aagtagatac caaaaattta
      121 tcaagagagc aagtagagaa gtgagtatat tcataagaga aatagctgta acgaattatt
      181 aggttaatgc aaatgcttat ttatactccg tataactttc tcagaaaaaa tgataccaat
      241 aatgacttgc tagtactgta aatccgtata atatcatcta atcaaaatgg tgttccattt
      301 gcatctgtca tcgtaatcga tccttcgggt gacactcgat aaaaaccaac gcttccagat
      361 cctccttggg aacggatttg tttgctggaa gctgtgaaca aataatctcg atcaattttt
      421 tgataaaagc taataacaat atcgtcactt tgtaattcgg aacggtgggc aataagaaat
      481 agaagtgctt tgtcagagtt ttctaatgga agagaaggta cagtgctttc ttgcatttca
      541 gatgttgaag aaatgctaaa cgactgaata cttgattggc tatgttgcga atctacatta
      601 ccagtagaag tattagtaat ggaagtagta gaagtacttt tagttgaacc aacctcagtt
      661 gttgaaatgg ctgctgaaga ttctttaaca gaattctttg ttttatatcc acaggcagaa
      721 aaaagtatta cagttcccaa caagcctgcg taaatccctt tatgcatgat agctcctcct
      781 aaaatagatt atctttattc agtatatcac ttaaacaaag aaaagcagat ggtttaaaat
      841 gaaaaaacct tcccaataaa gggaaggttc atgaagataa taactttttt aataattata
      901 gctttctaat atctttcatc aacttttcta gtaatcattg ggaaaaattt caagcagtag
      961 atcgcacaaa tacctacgac gatataaatg atcttcgcaa aaatagttgt tgaaccacca
     1021 gcaatcatag ctactaaatc aagttcgaac aagcctacca acagccagtt caaccctccc
     1081 acaatcaata aagttaatgc aatagcatct aaagttttca ttagaattct cctttcttaa
     1141 atgataaaac aattatatat caaaaagaga aacattgctt atataacgct caggaatttt
     1201 agcaatctat gcaaaaagat gaaaattttt tttgctcttc cattagtaca cattttttag
     1261 ctgaagctgt aaatttcatg tcttaatttt ttttagtgag cttttatact ggatttgtaa
     1321 gaaaaaagaa ggagaggatc acatatgtcg gattggttgg atattgcagg aaaagtagta
     1381 attgtaactg gaggttcctc aggaattgga agaagtatcg tcgaaaattt gttgaagcag
     1441 aatgcacaag tagcgaattt tgatgtaact gaatgccgta tacagcatga aaacctacta
     1501 tctttaaaag tcgatgtgtc ttctaaaacg gacatagaag aagggatata taaagtaatg
     1561 aaacatttca agacgatcga tggtctagtc aataatgcag gaataaatat tccttctctt
     1621 ctaatagata gaaatcatcc aaaaagcaag tatgaattat cagaacaagt ttttgataag
     1681 atgatcgctg tcaatcaaaa aagtgtatat ttgatgagcc aagcagttgg aagaatcttg
     1741 gtgcaaaagg gatcaggagt gatcgtgaat ctttcttctg aatcaggatt ggaaggatca
     1801 gaaggacaga gctgttatgc tgctacaaaa gcagcgatga acagttttac tcgttcttgg
     1861 gcaaaagagt taggaaagag gaatgttcgt gtggtaggtg ttgcaccagg gatactggaa
     1921 gaaaccggtt tgagaacaca agaatatgaa gaagctcttt cttatacgag aggtataagc
     1981 gtcgaacagc tgagaaacgg ttacagtcga acaagtacga tccctctagg aaggagtggt
     2041 aagctgcaag aagtggcgga tctagtctgc tattatcttt cagaaagatc aagttatatc
     2101 actggagtca cgactaatat ttcaggaggt aaaacaagag gataaaggat aggggggacg
     2161 cacgtgacgc tagtaaacag atggtaccaa ttattgaaat tactagtcac tcacaagaaa
     2221 gtttcaatcc aggaagtgca aaaagaaatc aaaaccagta atcaaaccat aaaaaaagat
     2281 attggggagt tgaatgaaga aattgccggt attgcaaaaa tcatccaaaa aaacaaacat
     2341 tttgaacttg aaatttatga ttttgatttt tttgatgaga tcatgcaagg aaaattgaaa
     2401 acagccagtg atttcaattc ggcatccaaa agaatcgctt atttactaaa taggctgatc
     2461 gaaacagagg atttcttacg tatggatgat ttgtctgaag aagtcggtgt cagcagagga
     2521 acagtggtca aggatctaaa gacattaaaa gagatgatca atgattttga tgtaaagatt
     2581 acaggcacac caaataaagg actaagaata ataggagatg agctagaatt acgactactt
     2641 ttattttatt ttgtttctcc ctacttttca gagacgaaaa cagaacagtt tctagaagaa
     2701 aaacaagcaa tcaaacattt tcagaagaag acgaatgcta gtaaacaaga aatcaccctt
     2761 ttaacgaaag ttatcggtat ttctttgaat agaatctcta gtaactatct gttgaagaag
     2821 cccatcaatc gttacagtgg gtgttttgaa tatatccaag aattcaatga actgatcaat
     2881 cagttggaag aaatctatga actaactttg agccaatatg aaaaagattt tatcagtttt
     2941 cctttgaaca tcatcaacac aagtataacg atgataagga aagctaactc tgatttgcgc
     3001 ttatatttcg accccatgat gatgcgtatt cgacgattag atctcattga tctggatgag
     3061 tccttcttat atcaagagat gaaacagcac ctctctttat tgataaatcg ggtaattttt
     3121 cgttatcgat tgactgattt attttatggt gagatagaaa aaaagtatcc tttttcttac
     3181 caaatcgcta gcgaatgcat acaagcatta gaagctatct tgcaacataa gatctctaaa
     3241 gtagagatca gctacctaac gttgtatttg gagttagcat ttcgatatca aaaagagcat
     3301 ttttcctcta aaaaagtagc cattgttcat acgacaggaa aaggaacagc attaatgatc
     3361 caaagacaaa tcaaaaggat attggggagg gatatacaaa taacacatgt ttcagaagaa
     3421 caatatgaaa aagtagatct aaacaaatat ttcgctgttt ttacaacgat tccgttaaaa
     3481 aatgtaaatg aagagacacc ggtgatccat ttgactaatc tttttgatga ctcttggtta
     3541 agggcacaat ggcaaaaagc aaaaaaaaag cgattagccg ggtttcattc tactgttttt
     3601 ttctatcaaa tatggaaaga aaaaaagacg tatcaagaat atttaaacaa attagtcgct
     3661 cctttgatca gaggctatta tgtggatgaa gaatttgaaa aaaggatctt gaaaagagaa
     3721 tatcagcaaa gcacatttgt taacaaagaa tttgcttttc ctcacacaac caaccagcta
     3781 tctcaacaca ttgttttatc agtagggcta ataactgatc aaggtttagc agaaacagga
     3841 ggaaatggag ttattttttt atttgccata cctgaagaaa tgacggctga agttgagaat
     3901 gaattatttg agctatacga tatcctattt gaactcataa aaatgggaat agatgagttt
     3961 attgaattag caccgacaca agaatcattt ttaaaactaa tcaaaagtaa aggagagaga
     4021 cttcatgaat gatatgtatc tattcatagt tttcgcagct tcagcttatg tgctgcaagc
     4081 agttatcagt tggaagcaac taaagcattt caatcaaaca tatagcgaac tgcgaagaaa
     4141 aggaaaagta gcgattggta aacgacctgg gaaaatccgt tcaggcacga ttgttatgct
     4201 agctatagac gatcatgatc aagttttaga agtcagaaaa atgcaagggg ttacatcttt
     4261 ggcaaaattt cattcattac ctgtctatgc gggtgaagat atccattaca tcgatcgtta
     4321 ccatccctca gttcgagcgg aagatcgttt gacacaagca gctttagaaa atgccagaga
     4381 agtatactta cgaatagagg caggaaatga aaaaagtgaa caaccttcat tgccttttat
     4441 tgctatgctc aataattttc ggatatggaa aagtacgatc aaagaaaaaa ggagtgacaa
     4501 acgatggata tcataacaaa atttgctgag ggatttatga ggctgttcca aacaggtgca
     4561 gaaacattca taagctggat gacaggaatc gtaccagttg tcttgatgct gatggttgca
     4621 atgaatacgc tgattgcttt tttaggtgaa gaccgagtaa cgaaagtagc caaattatca
     4681 gcgaaaaatc cgcttactcg ttaccttgtg ttaccgttct tatctgcttt tatgttggga
     4741 aatcctatgt catttacaat ggctcgtttc cttccagaat actacaaacc aagctattat
     4801 gctgctcaag ctcaattttg tcatacgagc aatggtgtat tcccccatat taatcctgga
     4861 gaattgtttg tatggatggg gattgctcaa gggatcgaaa ccttagggct aaattcgatg
     4921 gagctggcta tccgatactt gcttgtggga ctgctgatga actttattgg tggttggata
     4981 actgatttta ctactggatt tgtatgcaga cagcaaggaa tcgttcttag caaaaaagta
     5041 gagctttcag ttgattagag aaaggagagt tttaaatgta tggtgatatt aagatcgtaa
     5101 gaggaaacgg cgggtatgga ggtcctttga ttattaggcc gacaaaagat aaacacaagt
     5161 tcatctatgt cacaggtgga ggtgagaggc caatgatcgt agataaaata gaagaactga
     5221 caggtatgga gtctatcaat gggttcaaaa catcaatacc tgatagtgaa atcgcgcttg
     5281 caatcgttga ctgtggaggg actcttagat gtggaattta tcctaaaaaa gggataccaa
     5341 ccatcaatat cgtttccaca ggaaaaagtg gcccattagc acaatatatc actgaagata
     5401 tttatgtttc agcagtaggg ttagaacaaa tacagccact aatggaaact gatgataaca
     5461 aagaaacagt aaatactgca tctccagata aaaagtacaa atatgatact tctaaaaaga
     5521 taaccgagca aaaagcagag cagcaaaact ggatagcaaa aattggaatg ggcgcgggaa
     5581 aagtagttgc tacattcaat caatcagcaa gagaagcagt agatacgatg atccggacag
     5641 tgatcccttt tatggctttc gtttcccttt tgattggtgt gatacaaggt tctgggatcg
     5701 gtaatgtatt tgctaacatt atggcacctt tagcaggaaa tgcagttgga ttaacaatca
     5761 ttggctttat ttgttcactg ccatttttat ctcctttgct tggtccaggg gcagttatta
     5821 gccaagtgat tggaacattg atcggtgtag agattgggaa aggaaatatt cctccccaat
     5881 tagcattacc ggcactattt gctatcaata ctcaaaatgc atgtgatttt attccagtcg
     5941 gtctaggttt ggaagaagca aaagctgaga cagtagaagt aggtgtacca tcagttcttt
     6001 attcaagatt tcttaacggc atcccacgag ttatcattgc ttgggtagca agttttggat
     6061 tatatagctg
//
LOCUS       DACGEU010000123         6065 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.128, whole genome shotgun sequence.
ACCESSION   DACGEU010000123 DACGEU010000000
VERSION     DACGEU010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6065)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6065)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6065
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.128"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            832..1566
                     /locus_tag="IXR40_002613"
     CDS             832..1566
                     /locus_tag="IXR40_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAQ4362407.1"
                     /translation="MQNTFQSKSLYYQLVEILKQRIENSMVAHDKLPSERELTSFYGV
                     SRTTVRLALQELEKMGYIYRQHGKGTFVSELRTNATDLAGAYSFTEQMRAMGKHPETK
                     ILAFKKIEATKYLASHLNVQLGEPLFQLDRLRLADDLPMMIEKSYLPVKLFMSLSQEI
                     LFLKPLYNLFSENFNQIVRLADEEFYASIVQKEDSELLNIPEGSPVLHLVRSTYNLEN
                     EVIEFTLSVARADKFHYKIRHLRSTN"
     gene            1582..2751
                     /locus_tag="IXR40_002614"
     CDS             1582..2751
                     /locus_tag="IXR40_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAQ4362408.1"
                     /translation="MFMFSKEELRKLGAENTTREIRQQPELWHETFDRYQETVADLDR
                     LFTDAKQHAGERPIRVIFTGAGTSQYVGDTLIPFLTSQGNTNQFIFQSIGSTDIVATP
                     KEYLIPDETTILVSFARSGNSPESLAAVKMANQLVNKIYHIVITCAPDGLLATQMPTK
                     KENLVLLMPNKANDAGFAMTSSFSCMTLTALLIFDQASNQQKERYVHQLSRLGEEVIQ
                     RESEIQGYLASDFHRIIYLGSGSLGGLTREAQLKVLELTAGKIATVFDTSLGFRHGPK
                     SFVNEQTLVFLFVSNDSYTQKYDVDMLEEIKNDGIAQRVVGIGQKGSLFSGDSFELVA
                     DSLLPDGYLALADIMVAQTIALLCSVKVGNTPDTPSPSGTVNRVVKGVTIYPYEK"
     gene            2767..3762
                     /gene="lacD"
                     /locus_tag="IXR40_002615"
     CDS             2767..3762
                     /gene="lacD"
                     /locus_tag="IXR40_002615"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HAQ4362409.1"
                     /translation="MLEWSENKRQAMERLSTPEGIITALAIDQRGALKKMMSALGMEA
                     TKEKIEQFKTLISQELTPYASAILLDPEYGLPAAQKRAAASGLLLAYEKTGYDQTVPG
                     RLPDLLSDCSVLRLKELGADAVKFLLYYDYEEAEEINRQKQVFVERIGSECMAEGLPF
                     YLELLSYDAKNVDTKSLSYAKAKPRKVIEMMKEFSKTQYKVDVLKVEVPVNMSFVEGN
                     ATGEIAYTRQEAAAYFKEQSDATDLPYIFLSAGVSAALFMETLRFAKHAGARFNGVLC
                     GRATWKDAVAPFVEKGEAATLEWLTEQGTQNIRQLNEVIRETAIPWYEKVSESTC"
     gene            3841..4767
                     /locus_tag="IXR40_002616"
     CDS             3841..4767
                     /locus_tag="IXR40_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HAQ4362410.1"
                     /translation="MNKRLLDYSASDFLKAKPMELKQAILASEGRTIMAENVPSSCPY
                     MGKSVTNAELERAAGADLILFNALDLFNPQISGVPLTLKENPIIWIKKALGRAIGVNL
                     EPVDKEVLMSENRTEISSGRIVSPETLKKANELGFNFICLTGNPGTGVSNRTIEKAIT
                     LSKSIFNGLIIAGKMHGAGVDEPIMNLDIAKRFIKTGVDILLVPAPYTVPYFMESDLR
                     GIVDYIKDFNRNKSIEEKVLVLTANGTSQDSSDQETIKKIALASKACGADIQHIGDSL
                     NGICLPENIFALGQAIRGYRHQIIMLGKSNYR"
     gene            4786..6036
                     /locus_tag="IXR40_002617"
     CDS             4786..6036
                     /locus_tag="IXR40_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4362411.1"
                     /translation="MIDKVQKIAAKISNQRHLLALRDSMAAVMPLIIIGSFFMLLANF
                     PIEGFTKWLSEIGVQSFLNKASDSTFGIIGLAVTYSLGHNLAKTYGVDSLSAGLLSLS
                     GYVLLTPLLDADGSIGFPTKYFGTSGLFVGIIVALVSTEIFRWFVLKNITIKMPASVP
                     PNVSRAFVAIIPGFFVVLLWFIVVVICYKLGIENVHALIADTLAKPLSLLTKTLPGII
                     LVILIQCFFWMFGIHGAQVTGPIIEPLLLQNSDVNRIAYQAGKELPNIITYEFLYNFV
                     FSGGAGCLFALAILTFFFSKSQENKTLGKLSIAPVSFQVAEPLLFGFPTILNIKMLIP
                     FVTAPVVTTLITYFSMSMGLVAKPVGATIPWTTPPIIAGFLASGGRISGAVIQVITIA
                     INVLIYYPFFKLDDNAKLKSEKND"
BASE COUNT         2025 a          997 c         1246 g         1797 t
ORIGIN      
        1 attggcgcag cgaatccttg ataatgagct cggatgtgct aacgctagcg aggcagtcta
       61 actttaactg ttagctcctg ccgaagatcg tcacatccga ggaggctcat tgtcaaggac
      121 aatcggaata gcatacggaa agaagttctg caccttataa aatttgtcaa aaaaactgtt
      181 gccattccaa agtttgaaaa atgctatttc gaggtagaag gatattatat aagcacggtt
      241 gactaaacga agtgataata aaaaaagtta ttcaagaata agaaaaatta tgatacgaat
      301 tcagataaac tggagaatac agagaccttt aaaagggata agaaacaaca taaattcctc
      361 ttaagagaga acgaaaggac aaagccagca acttgataca cgagctagta ttagaggaat
      421 ttattctcat agactccctt ttgaatacgt ttcaacttta attttcatgt tcataaatga
      481 tttgaaacca aagcaaatgc gttgcacttt tcctccgtct tccgaaaatc gttcaattca
      541 ctggtaagta gtcatttgat agtttgaggc aaattgttga ttgatgaagg gtaggagcta
      601 aaaaaagata ccagttgaag agagaaaaag aaaaaaatag agggtgttct tgaatgaaaa
      661 aagttggaaa attatttttc atttcctttt attcctatta aagtcagtga tgtcaatcat
      721 attaacaaga ctaaaaatga aaataaaaaa aagattgttc ttagtattga ctcataaaaa
      781 ataccactac tatacttaca ttgtggttat agccagttag gagagacatc gatgcaaaat
      841 acctttcaat caaaatcact ttattatcag ctggtagaaa tattgaaaca acgaatcgaa
      901 aacagtatgg tcgctcatga caagctgcca tcagaaagag agttgaccag tttttatggc
      961 gttagtcgca cgacggtgcg actagcattg caagaactgg aaaaaatggg ctacatttat
     1021 cgacaacatg gaaaaggaac ctttgtttcg gaattaagga caaatgcgac tgatctagct
     1081 ggcgcatata gttttaccga acaaatgcgg gcaatgggca aacatcctga aaccaagata
     1141 ttggccttca agaagattga agcaactaaa tatttagcga gtcatctgaa tgttcaacta
     1201 ggtgagcctt tatttcaatt agaccgattg cgcttagctg atgatttgcc aatgatgatc
     1261 gagaaatcct atttgccagt gaagctattt atgtcccttt ctcaagaaat tctatttctg
     1321 aaacctttat ataatttgtt ttcagagaat ttcaatcaaa tcgtacggtt ggctgacgag
     1381 gaattttatg ccagcattgt ccagaaagaa gatagtgagt tgctaaatat tccagaagga
     1441 tcaccagtgc tccatttagt tcgctcaacc tataatctcg agaacgaagt gattgaattt
     1501 acattaagtg tagcgcgggc tgataaattt cattataaga tcaggcatct gcgttccact
     1561 aactgaattg gaggaaagaa aatgtttatg ttctcaaaag aagaactacg aaagctagga
     1621 gcagaaaata ctacccgaga aattcgacag caaccggaac tgtggcatga gacgtttgac
     1681 cgttatcaag aaacagttgc agatttagat cgtttgttta cggatgcgaa acaacatgct
     1741 ggagagcgac caatccgagt catttttaca ggggccggaa cctcgcaata tgtgggagat
     1801 acactaattc cgtttcttac tagtcaagga aatacgaacc agtttatttt tcaaagtatt
     1861 ggttcgaccg atatcgttgc tacgccaaaa gaatacctga ttcctgatga gacaacgatc
     1921 ttggtctcat ttgcccgtag tggaaatagt ccagaaagtc tagccgcagt taagatggcc
     1981 aatcagctgg tcaacaagat ctatcatatc gtgatcacct gtgcaccaga cggattattg
     2041 gctacacaaa tgcctacaaa aaaagaaaat ctagttttac taatgccaaa caaagccaat
     2101 gacgctggtt ttgctatgac aagcagtttc agctgtatga cgctgactgc gctacttatt
     2161 tttgatcaag caagcaatca gcaaaaagaa agatatgttc atcaattaag ccgactagga
     2221 gaagaagtca tccaacgaga atcagagatc caagggtatc tggcatcaga ctttcatcgc
     2281 atcatttact taggttcggg aagcttaggc ggattgacta gagaagcgca attaaaagtt
     2341 ctcgagttaa ctgctggaaa aatcgcaacc gtatttgata catctttagg attcagacat
     2401 ggtcccaaat cttttgtcaa tgagcaaaca ttggttttcc tgtttgtcag caatgactca
     2461 tatacgcaga aatacgatgt agacatgctg gaagaaatca aaaatgacgg tattgcccaa
     2521 cgcgttgttg gaattggtca aaagggttca ttgtttagtg gtgattcctt tgaattagtt
     2581 gcagattcgt tactgccgga tggctatctt gctttagcag atatcatggt agcccaaacg
     2641 atcgcattac tttgttcggt gaaggttggt aatacaccag atacaccatc gccaagtgga
     2701 acagtcaatc gtgtggtcaa aggcgtaacg atttatccat atgaaaaata ggaaagagtg
     2761 tgaagcatgt tagaatggtc ggaaaataaa agacaagcaa tggaacgtct atcgacgcca
     2821 gaaggcatta ttaccgcttt ggcgatcgat cagcgaggcg cgctgaagaa aatgatgtcg
     2881 gctttaggga tggaagcgac aaaggaaaaa attgagcagt ttaaaacact aatttcccaa
     2941 gaattgactc cttatgcctc agcaatttta ttggatcctg aatacggact gcctgctgca
     3001 cagaagcgtg cagcagcgag cggtctgctg ttggcatatg aaaaaactgg ttatgatcaa
     3061 accgtacccg gccgcttgcc ggatctgctg tcggactgtt cagttctgcg attgaaagag
     3121 ttaggtgcgg atgcggtgaa atttttactg tattacgatt atgaagaagc agaggaaatc
     3181 aatcggcaaa agcaagtttt tgttgaacga attggaagcg aatgcatggc tgaaggactg
     3241 ccattttatt tagagttatt gtcatatgat gctaaaaatg tagatacgaa atcgctttcc
     3301 tatgccaaag caaaaccgcg caaagtgatc gaaatgatga aagaattctc gaaaacccag
     3361 tataaagtag atgtcttaaa ggttgaagta ccagtaaaca tgtcatttgt tgaaggaaat
     3421 gcaacagggg agatcgccta tacacgtcaa gaagctgccg cttattttaa agaacaaagc
     3481 gatgcaacag atttgccgta tatcttctta agtgctgggg tatcagcggc attattcatg
     3541 gagacattgc gttttgccaa acatgctggg gcacgattca acggtgtact ctgtggcaga
     3601 gcaacttgga aagatgcagt cgctcctttc gttgaaaaag gagaagcggc aactttagaa
     3661 tggctgacag aacaagggac acaaaacatt cgtcaattga atgaagtgat aagagaaact
     3721 gccatcccat ggtatgagaa agtaagtgaa agcacttgtt aatgtttcta atatattagt
     3781 agtgataaga gatatgtgtg attataattt atcattattg aaactgggag gatattttat
     3841 atgaataaaa gattgttaga ttattcagct tcagattttt tgaaagctaa gccgatggaa
     3901 ttaaagcagg caattttggc ttctgaaggt agaacaatta tggcagaaaa tgtgccaagt
     3961 agctgtcctt acatgggaaa atcagtgaca aatgcagaat tggagagagc tgctggagct
     4021 gatttaattt tgtttaatgc actagatctt tttaatcctc aaatttcagg tgtaccttta
     4081 actctaaaag agaatccaat aatctggatt aaaaaagctt taggaagagc tattggtgta
     4141 aatttagaac ctgtagacaa agaagttttg atgagtgaaa atcgaactga aatttcaagt
     4201 ggtagaatcg tttctcctga gactttaaaa aaggcaaatg aattaggctt taattttatt
     4261 tgtttaactg gaaatccagg aacaggagta tctaatagaa ctattgagaa agcaataaca
     4321 ttatccaaat caatttttaa tggattaatt atcgctggaa aaatgcatgg tgctggtgtt
     4381 gatgaaccaa ttatgaactt agatatagca aaaagattta ttaaaacagg tgtagatatt
     4441 ttattagttc ctgctccata cactgttccg tatttcatgg aaagtgattt gcgaggaatc
     4501 gttgattata taaaagattt taatagaaat aaatctattg aggaaaaagt tctagtacta
     4561 acggctaatg gaacaagcca agactcttct gaccaagaaa ctattaaaaa aattgcatta
     4621 gcatcaaaag catgtggagc tgatattcaa cacatagggg attctttaaa tggtatttgt
     4681 cttccagaaa atatttttgc tttgggtcaa gcaattcggg gatatcgtca tcaaattatt
     4741 atgttaggaa aatctaatta tcgttaatta aggaggaaat gaaagatgat cgacaaagtt
     4801 caaaaaatag ctgcaaaaat tagtaatcaa agacatctac tagctttaag agacagcatg
     4861 gctgcagtta tgccattaat cattattggt tcctttttta tgttattagc aaatttcccg
     4921 atagaaggat ttacaaaatg gttatctgaa attggagtac aatccttttt gaacaaagca
     4981 tcagattcaa catttggtat tattggatta gctgttacct actctttggg acacaatcta
     5041 gcaaagactt atggtgtaga ctcattatca gcaggattat tatctttgag tggatatgtt
     5101 ttacttacac ctttattgga tgcagatggt tctataggat ttccaacaaa atactttggt
     5161 acctcgggtc tttttgttgg tattattgta gcacttgtat ctacagaaat tttccggtgg
     5221 tttgtactta aaaatattac aattaaaatg ccggcaagcg ttccaccaaa tgtaagccga
     5281 gctttcgttg ctattattcc tggctttttt gtcgttctac tatggtttat tgttgttgta
     5341 atttgttata aacttggaat tgaaaatgtt catgctctta ttgcagatac actcgcaaaa
     5401 ccactatctt tactgacgaa aactttacca ggaattatat tggttatact tattcaatgt
     5461 ttcttttgga tgtttggtat tcatggtgca caggtaacgg ggccaataat tgaaccgtta
     5521 ttattgcaaa actctgatgt aaatagaatt gcttatcaag ctggaaaaga acttcctaac
     5581 attataactt atgaattctt atataacttt gttttttctg gtggtgcagg ttgtttattt
     5641 gcacttgcca ttttaacatt tttcttttca aagagtcagg aaaataaaac tttaggtaag
     5701 ttatcaatcg ctccagtaag ttttcaagta gcagagcccc ttctatttgg gtttccaact
     5761 atattaaata taaaaatgtt aattccattt gtaactgcac cagtagtaac aacattaatt
     5821 acttattttt caatgagtat gggattagtt gcaaaacctg taggagcaac aatcccatgg
     5881 acaactccac cgataattgc cggattttta gcttctggtg gacgaataag tggtgcagtg
     5941 attcaagtaa taacaattgc aataaatgtt ttgatatact atccattctt taaattagat
     6001 gataatgcca agctaaaaag cgaaaaaaat gattagaact acctatatgt ttctaactgt
     6061 agtta
//
LOCUS       DACGEU010000124         5989 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.129, whole genome shotgun sequence.
ACCESSION   DACGEU010000124 DACGEU010000000
VERSION     DACGEU010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5989)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5989)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5989
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.129"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(711..986)
                     /locus_tag="IXR40_002618"
     CDS             complement(711..986)
                     /locus_tag="IXR40_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgO"
                     /protein_id="HAQ4362412.1"
                     /translation="MALLPTNKDKKKIGAEDISIKDDINVELGERKYTAKERKPVQVD
                     PPVLKTIRDLSYAKDIPMYEIVKLAMDAYVDTLNDEERIIYNRRSKD"
     gene            complement(958..1911)
                     /locus_tag="IXR40_002619"
     CDS             complement(958..1911)
                     /locus_tag="IXR40_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAQ4362413.1"
                     /translation="MENLRTAFKTSDKLGKVVMLTGRKGGIGKTTDNDLLAIVSSQLF
                     EKDVLLIDYDQQRNTTSNIGSTYQITSFDRSMSAAIKKGDWVSGITQVSPHLYIMAGS
                     PGSEELNEYLSEKYPDRRKRSLAFIKPLEELRKNFDYIFIDCPPSTDNVVRAFLTAAD
                     YIIAMQELKRYAMEGTEDFINKVLVPIVTNFEESHLQIIGILPVLFSVRRSSQHANYQ
                     KTIDKYGESNIFKSIVKGSDRLEMYGENGIQLNDYVDRRWWAIFADIFTELEERIEYY
                     EQHGDIEGFDYTPKYADSMANHILPLGKEIKLNGIITNEQR"
     gene            2523..4016
                     /locus_tag="IXR40_002620"
     CDS             2523..4016
                     /locus_tag="IXR40_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein RepR"
                     /protein_id="HAQ4362414.1"
                     /translation="MLSEIYSAILKNGLRTYKYRNSTMKPAGHIDSSRSGAIFAYRSK
                     QLMNVGRGMVITSEEAILENEKKLTHWTPNTYRFGTYADDYRTVVKGHSEKNLSQINT
                     FVVDIDSKENHQGEIILACLDQVGYMPTLILESDHGYQVYFVLKTPGYVTKKSNFKVI
                     DVAKKISKTIRLQLAEKLSGVDLGCNHFGIARFPQENNIVFKEMNYQYSFADWIQWSM
                     KLESDQKTKEDRERKLIVFPEKKEIRQVDEPWFDMLLHKANIVGGEGRLGRNNVIFTL
                     SLAYYSSGYALDTCEYNMFTFNERLQEPLSEAELVKIVRSAYSGNYQAASREFIIELC
                     QQWVSPTLKNNDLFIQRRGWWKFKKPRDQRKYSHKNEWKEDLLAYLSEKSLASEPYLN
                     LSKKELASQLTMPKRTLDKILNELREENKVFYKVTRGRNGGMIIASVKTLFARVIQLS
                     KEKRLDYSTRITEVFGLNESLVEETFRQLSTPLNPLKEVNLFEVDTG"
     gene            4151..4447
                     /locus_tag="IXR40_002621"
     CDS             4151..4447
                     /locus_tag="IXR40_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HAQ4362415.1"
                     /translation="MSLKNYVYSHPVNVFIIGRLGLSVEVFCELYGFKQGTLSSWVTR
                     EKTVASLPIEFLHGLSLASGETMDQVYDCLCVLEQEYIEYKIANELRKRKKYIQ"
     gene            4548..5399
                     /locus_tag="IXR40_002622"
     CDS             4548..5399
                     /locus_tag="IXR40_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362416.1"
                     /translation="MKSDDWIEHTWLPLKRNSKRKKFWVLQLWPLGKLCSYGARLILD
                     LTVYSIGVFGTAYYLINDPNRIAASDIFTVLMTLIFVMLLSIFTQLVMQFTRQKLTAG
                     KLFKSLFDLIVVNAILATLIKQIEQSGRTTKGVKDFLLTFIHFVNGHMYLFEVGIILF
                     FVGYVSTKLIKRSIEKEIEIDLIPTLLGYEYNVDFGRYDELINTDIVHTSIHESTVKG
                     IRSILKNGQEMKAIDRRKEIYNFYEVEASLRYGIGKLWLDGSNIRQNKPYIFWNSSDL
                     ELPMKDK"
     gene            5420..5632
                     /locus_tag="IXR40_002623"
     CDS             5420..5632
                     /locus_tag="IXR40_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362417.1"
                     /translation="MIPLYRIVLIVGMELKTLKKEQLFKVKERHNQLLCSKTGTMNIE
                     YRTEYLELTNQTDFLLIRKQQEQEKN"
BASE COUNT         2058 a          934 c         1099 g         1898 t
ORIGIN      
        1 attgagacca gcttattcag ctaaatatag ttgaataagc ttcttttgtt ttaaaaaaac
       61 aaaaggtgta ctacgaataa cgcaagtaaa agaaatacta ttacaaccag taggctacaa
      121 gtaagtatta ctaaacattg cgtagttaga acctttgctc tattgtctaa agccacaaaa
      181 ttagagatca gctttatgat gctaagagcg agctgcatcc atgcggacat aggttctttt
      241 gacactatta attctccttt ttaggataag ggaaattgct agtagttttt tcattagcac
      301 catccccctt catttgattg agtctagtgc tgctgtgata gtttgctgtt taatatgctt
      361 acattcttat tataacataa atgaaacaaa cacatggtta gaggtcgtat caatcaaaat
      421 agtgtctcac aaacgattta ttacttactc ctgctgacta acggactgtt cttcagtaac
      481 tgtaactata tgtttgttaa aaccaccatt acctgtagat aaaaaccaat atatttacta
      541 tactcactat attaaatata tttagtatag taaaaactag aaacaataaa atttgtgaat
      601 gttgtatacc cccaaacaat acacatattt tgaaggatta ggattaataa agctaaaaat
      661 atagtaagta tactaaatat atttactata tctagtatac ttactatatt ttaatctttt
      721 gatcgtctat tatatataat ccgttcctcg tcgtttaaag tatcaacata ggcgtccatt
      781 gcaagtttga ctatttcata cataggaata tcttttgcat aactaagatc ccgaatggtt
      841 tttagtacgg gaggatctac ttgaactggt tttctttctt tcgcagtgta ctttcgttcc
      901 cctaactcga cattaatatc atctttaatt gaaatatctt cagcaccaat tttcttctta
      961 tctttgttcg ttggtaataa tgccatttag tttaatctcc tttccaagag gtaggatatg
     1021 attggccatt gagtcagcat atttaggtgt ataatcaaat ccttcaatat caccatgttg
     1081 ttcatagtat tcaattcttt cttctaattc tgtaaagatg tctgcaaaaa tagcccacca
     1141 tcttcgatct acataatcat ttaattggat accattctca ccatacattt ctaaccgatc
     1201 cgagccttta acaatgcttt taaaaatgtt tgattcacca tacttatcaa ttgttttttg
     1261 atagtttgcg tgttgagagg aacgtcgcac tgagaaaaga acaggcaaaa ttccaatgat
     1321 ttgaagatga gactcttcaa aattcgtgac aatcggaact aaaactttat taataaaatc
     1381 ttctgttcct tccattgcgt accgttttaa ttcttgcatt gcaataatat aatctgcagc
     1441 agttaagaat gcacgaacca cattatctgt tgatggtggg cagtcgataa agatataatc
     1501 gaaatttttt ctcaattctt ctaaaggttt aatgaaggcc aatgatctct tacgacgatc
     1561 aggatatttt tcggacaagt attcattaag ttcttcagat ccaggagagc cagccataat
     1621 atataaatgt ggacttactt gagtaatacc tgaaacccag tccccttttt tgattgctgc
     1681 agacatggat cgatcaaagc tagtaatttg atacgttgat ccaatgttgg aagtagtatt
     1741 tctttgttgg tcataatcaa ttagcaacac gtctttttca aaaagttgac tagaaacaat
     1801 cgctaataaa tcattgtctg tagtcttacc aatgccgcct tttctacctg taagcattac
     1861 aacttttcct agtttatctg atgttttaaa tgcagtccgt aagttttcca tagttccctc
     1921 caatttccta tactaaatat atttagtata cttcatatac ttaatatatt cgatatatct
     1981 aatatactcc aaattgataa gaattcagac tttataagga atatagtgga tatactaaat
     2041 atatttgcta tattcagtat atcagatata ttcaaaatgt caaaatatat ttgtgcgttt
     2101 tgcgttgaca atttagagtg aaaagaggta aacttaattc tatagaaacc acagataatt
     2161 cactatttac aaagtagcaa aagcagtggt actctttaaa cagaaaaatt acataaaaaa
     2221 aagagacgga aataattgat tttagcagaa tcaattattt ctgaatcaca tggttaggac
     2281 atgtgttcac gctcgtctca agaatatgta agtagctacc aactacttat attaaaagtt
     2341 gatcggatac cttttccgat tgcctttatt ctaccaaaaa aaggcgagca actcaacaga
     2401 agaacgttta tttagtgtac ttaaattaaa tattcttaaa cactgaagag agaacacata
     2461 ctatggctga gattaaagct aaactgtgtt ctctttttgt ttgagaaagg acgttacaat
     2521 cgatgttgag cgaaatttat tcagctattc ttaaaaacgg cttacgtaca tacaaatatc
     2581 gaaacagcac catgaaacct gcaggtcata ttgattccag taggagtggt gctatctttg
     2641 cgtaccgtag caagcaatta atgaatgttg ggcgtggtat ggtcattact tcggaagaag
     2701 ctattttaga gaacgaaaag aaactaacgc attggacacc taatacctat cgctttggta
     2761 cttatgcgga tgattatcga acagtggtta aaggtcattc tgagaaaaac ttaagtcaaa
     2821 tcaacacatt tgtagttgat atcgattcaa aagagaacca tcaaggcgaa attattttag
     2881 cctgtttaga tcaagtgggc tacatgccaa cgctaatttt agaatcagat catggttatc
     2941 aagtttattt tgtactaaag acaccaggct atgtcacaaa gaaaagcaat ttcaaggtga
     3001 tcgatgtagc aaaaaaaatt tcaaaaacaa ttcgtctaca gttggctgaa aaattgtccg
     3061 gagtggatct aggatgtaac cacttcggaa ttgctcgatt cccacaagaa aataatattg
     3121 tttttaaaga aatgaactat cagtattctt ttgctgactg gattcaatgg tcgatgaagc
     3181 ttgaatcaga tcaaaaaaca aaagaagatc gagaacgaaa actaattgtc tttcctgaga
     3241 aaaaagaaat tcgtcaagta gatgaaccgt ggttcgatat gttacttcat aaagcaaaca
     3301 tcgtcggcgg agaaggacgt cttggtcgaa ataatgtgat tttcacgctt tctttagctt
     3361 attactcttc aggttatgca ttggatactt gcgaatacaa tatgttcaca ttcaacgaac
     3421 ggttacagga accgctatct gaagcagaat tagtaaagat tgtacgtagt gcttattctg
     3481 gtaattatca agcagcaagc agagaattca ttattgaatt gtgccagcaa tgggtttcac
     3541 caaccttaaa aaataatgat ctgttcattc aacgacgtgg ctggtggaaa tttaaaaagc
     3601 cacgagatca aagaaaatat agtcataaaa atgaatggaa agaagatcta ttggcttatc
     3661 taagcgaaaa aagtcttgct agtgagcctt atttgaacct gtcaaaaaaa gaattggctt
     3721 cacaactaac gatgcccaag cgaacacttg ataagatctt aaatgagtta cgagaggaga
     3781 ataaagtctt ctacaaggta acacgaggaa gaaatggcgg aatgatcatt gcttcagtca
     3841 aaacgttgtt cgcgagggtt attcaactaa gtaaagaaaa gagactagat tattcaacaa
     3901 ggatcacaga ggtatttgga ctcaacgaga gcttagtaga agagacattt agacaattat
     3961 caaccccctt gaaccctctt aaagaagtga atctttttga agtagataca ggttgaaaaa
     4021 taaaaggtgc aaattgcctt atacaatata tctatgatac ttctgtaggt gttgctccct
     4081 ttgcctagct acgtgtaggt ggtatactta taactgcgta tgcagtctta tgtatcatgg
     4141 aggaagttgt atgtcgttaa aaaattatgt ctattcacat cctgttaatg tgtttatcat
     4201 tggtcgtttg ggattatctg tggaagtgtt ctgtgagctt tatggtttta agcaggggac
     4261 tttgtcttct tgggttacca gggaaaaaac agttgcttct ttgccgattg agtttcttca
     4321 tgggttgtcc ttagcttctg gggagactat ggatcaggta tatgattgtt tgtgtgtgtt
     4381 agagcaggag tatattgagt ataaaatagc taacgagtta agaaaaagga agaagtatat
     4441 ccagtagtag tttttattta cttaaaaaat tggttcattg agcaacctat cgctgctaaa
     4501 gtagcaaagg aaaacgttaa aggaaagaat ttagggaaga aatcgaaatg aaatcggacg
     4561 actggattga acacacctgg cttcctctga aaagaaatag caaacgaaag aaattttggg
     4621 tattgcaatt atggccatta ggaaaacttt gtagttacgg ggcacgactt attcttgatt
     4681 taaccgttta ctcgattgga gtatttggaa cggcttatta cttgataaat gatcccaata
     4741 ggattgcagc atcagacatt tttacagtgc taatgacgtt gatttttgtc atgctattgt
     4801 ctatttttac tcaattagtc atgcaattta ccaggcaaaa attaacagca ggaaaacttt
     4861 tcaaaagcct attcgattta attgttgtaa atgcaattct agcgacttta ataaaacaaa
     4921 ttgaacaatc tggaagaaca acaaaaggag tgaaggattt tttattgacg tttattcact
     4981 ttgtaaatgg acacatgtat ttgtttgaag tgggtattat tctctttttt gtcgggtatg
     5041 tatccacgaa acttattaaa cgttcaattg aaaaagaaat tgaaattgac ctgattccga
     5101 cacttcttgg ttatgagtac aatgttgatt ttggaagata tgacgaattg atcaatacgg
     5161 atatcgttca cacgagtatc catgaatcta ctgttaaggg catcagatct attttaaaaa
     5221 atggccagga aatgaaagca atagatcgaa gaaaagagat ctacaatttt tatgaagtcg
     5281 aagcaagcct acgatatggc atcggaaaat tgtggttaga tggaagtaat attcgtcaaa
     5341 acaaaccata cattttttgg aacagtagtg atttagaact tccaatgaaa gataaataat
     5401 tatggagaat cgtttgaaaa tgattcctct atacaggatt gtgcttatag ttggcatgga
     5461 gttaaaaacc ttaaagaagg agcagttatt caaagtgaaa gaacgtcata atcagttact
     5521 atgtagtaaa acgggtacga tgaacattga ataccgaaca gaatatttag aattaacgaa
     5581 tcaaactgat tttttgttga ttcgaaagca acaagagcaa gaaaaaaatt aatggctact
     5641 tatagccaat tgattgatga atgggaacaa ttcaaggaat ctaaaattcc agaacgtctc
     5701 taaaagcctt tatttgtaaa gagcataagg aaacgtggga acacttttta aaaaaagtgt
     5761 tccaataggc tgtgcctatt acgtttctca aaaataaatg tgggaacaaa atatttaaaa
     5821 ataggatagt gaaaggatag tgaaggatag taaaaggagg gtagtaggat agcaaaaagg
     5881 ataggctcct tttcgctatc ctttttaaat tggaggaatt aatatggaag taagaataag
     5941 aaatgtggat gagaaaatcg taagagaaat tgatcgaaga tgtgacgaa
//
LOCUS       DACGEU010000125         5972 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.130, whole genome shotgun sequence.
ACCESSION   DACGEU010000125 DACGEU010000000
VERSION     DACGEU010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5972)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5972)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5972
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.130"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            <1..500
                     /locus_tag="IXR40_002624"
     CDS             <1..500
                     /locus_tag="IXR40_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (hydrolyzing)"
                     /protein_id="HAQ4362418.1"
                     /translation="IEKQILALINSMEQQSQPIICILPNSDAGSEIIRKMYQKYLKTD
                     IIYITNLEPEEYLTILKECKFMIGNSSSGIIEAASFKIPVINLGTRQNGREQSKNIIN
                     ANLNENEIETALNKIQDPQFIKSLKNVKNIYGDGNSSRRITKTLNQILNDGEDIKWIQ
                     KQIAY"
     gene            473..1150
                     /locus_tag="IXR40_002625"
     CDS             473..1150
                     /locus_tag="IXR40_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HAQ4362419.1"
                     /translation="MDSKTNSLLKYTSDPYIIIGAGGHAKVIIETLRLENKLIYGFFD
                     DKQNKMQDLKYLGKINELNSWADSKKKIYKFIVAIGDCVVRKKIIKKLNMPSEQYGIA
                     VHPSAIVAKEISIGYGTVIFANAVINPDAVIGEHAIINTGSIVEHDCRINNYVHLSPG
                     VCLAGGVHVGVGTQIGIGSQCIQMKKIGSWCMIGAGSTIVKDIPSHSLAYGNPAKIKK
                     EGINFEF"
     gene            1140..2282
                     /locus_tag="IXR40_002626"
     CDS             1140..2282
                     /locus_tag="IXR40_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HAQ4362420.1"
                     /translation="MNSRILLSSPHMGGTEEKYVAKAFKDNWIAPLGENVDKFEESIT
                     KYTGSKGGASALSSGTAAIHLALRLLNVGKNDIVFAPSFTFIATVNPILYQGAVPVFI
                     DSEPNTWNMSPVALESALEEAERNNQLPKAIIVVNLYGQMADYERILAIANQFNVPVI
                     EDAAESLGSTYKGISSGLFGTIGIYSFNGNKIITTSGGGALVSSDKKYVEHSRFLATQ
                     ARDQAPYYQHSEIGYNYRLSNISAGIGRGQMEVLNDRVAKRREIFNRYKEAFSGIDRI
                     EMMPEVDGMVPNRWLSTLTINDYNSIDQVVNVINKLNEKNIETRALWKPLHLQPVFQG
                     VKMYYHDNNLSVSEKLFNSGLCLPSGSNMTDSEQEFVIDEFKKIFK"
     gene            2295..3272
                     /locus_tag="IXR40_002627"
     CDS             2295..3272
                     /locus_tag="IXR40_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAQ4362421.1"
                     /translation="MNIGIIGLGSMGKRRLRLIQEHFNDILLCGVDTNEARRKEVEKE
                     FGIPTYNSLTEAKNLFEINSVFVCTSPITHEFIIKEALNLDCNIFTEINLLNEYYDEI
                     IEVAKKKDRLLYLSSTFLKRKEIQYIKSKVTHNKKISYQYHVGQYLPDWHPWEDYRNF
                     FVSNKKTNGCREIFAIELPWIIDTFGKVKSFTVMTQKLSNLDIDYSDSFTLIIEHETG
                     IVGTLSVDVVSRVAKRNLTIIGEKILIEWEGNPDSLFSWNEETSSMTDIQLYDEVMHD
                     NNYSHTIIEDAYLEEIKEFFTLLEKKMEPQYTFEKDKYIINLINDIEVN"
     gene            3272..4180
                     /locus_tag="IXR40_002628"
     CDS             3272..4180
                     /locus_tag="IXR40_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HAQ4362422.1"
                     /translation="MMKVIFFGLGSIGKRHLKNLISYGKKNSINFDITAYSSSGKKEF
                     EEITYIQNRDDLDTHYDIAFITNPTFKHLETLNVIVEKVDYIFLEKPAFSESIDLTQY
                     NYDYKNIYVAAPLRYKNIMEVVRNSIQSKKVYSVRAICSTYLPDWRKGTDYRNNYSAF
                     KSMGGGVELDCIHELDYIINLFGFPKSVKKQFGKYSNLEINSNDLATYILRYDDKIIE
                     IHLDYFGRVPTRKFQLFTLDECINVDLLNNKISFEENIVKEMPESANDMYEKELKYFF
                     ENVVTGKENWNDLYHANEVLKIAEEK"
     gene            4181..4933
                     /locus_tag="IXR40_002629"
     CDS             4181..4933
                     /locus_tag="IXR40_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HAQ4362423.1"
                     /translation="MEILFTICGRAGSKGFKNKNLKYLAGKPLVHFALAMIDIYQQKH
                     PEHNCTTCLNTDSNELVELTTKLNPSVKIVERKPELATDTVGKIEVIRDSFLQLERED
                     NIFDLIIDLDLTSPLREVSNLEELIDEHLKNLDKDVYFSVVSARRNPYFNMVKRIENE
                     VTIVNKSRYTSRQQTPEVFEMNASMYSFKPEFLKKSNYIFDGQCGIIKMRDYLILDID
                     SEEDFKWLEFLFPKFLEDSSELQDIYNYLYRR"
     gene            4938..5885
                     /locus_tag="IXR40_002630"
     CDS             4938..5885
                     /locus_tag="IXR40_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HAQ4362424.1"
                     /translation="MSCYLITGGAGFIGSTLANHLGEEHVVIVVDDLSMGKVENLDMT
                     KNITFIEGDVAEKSLMEEIMKANKFDYIFHLAAVASVADSVARPVETHRVNFESVLMI
                     LELIRKYQPDLKRIVFSSSAAVYGDEPTLPKKEESVIRPLTPYAVDKFAAEQYVLDYC
                     HLYDVPGSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQIVGEATSFTLFGDGSQSR
                     DFVYIDDVIQALLLVANEEAALGKQFNVGTGKATTLLELIHAINEILGVELTLEYKEE
                     RSGDIHDSLADITKIQSIGYQPKYGILSGMTNYLKTEIN"
BASE COUNT         2193 a          753 c         1133 g         1893 t
ORIGIN      
        1 atatagaaaa acaaatttta gctttgatca attcaatgga acaacaatct caaccaatta
       61 tttgcatttt acctaatagt gatgctggta gcgaaattat cagaaaaatg taccagaaat
      121 atttaaaaac ggatattatt tatattacga atttagagcc ggaggaatac ctgactatat
      181 taaaagagtg caaatttatg atcggaaatt cttcttctgg gataattgaa gctgcatcat
      241 tcaaaatacc agtaataaat ttaggaacca gacaaaatgg acgagaacaa tctaaaaata
      301 ttataaatgc aaatctaaat gaaaatgaaa ttgaaactgc tttgaataaa atacaagatc
      361 ctcagtttat aaaaagcttg aaaaatgtta agaacatcta cggtgacggc aacagttcta
      421 gaagaataac aaaaacattg aatcaaatat tgaatgatgg ggaagatatt aagtggattc
      481 aaaaacaaat agcttattaa aatatactag tgatccatac attattattg gggctggcgg
      541 acacgcaaaa gtcattattg aaaccttaag attagaaaat aagttaatat atggattttt
      601 tgatgataag caaaataaaa tgcaagatct gaaatatctt gggaaaataa acgaattgaa
      661 tagctgggcg gatagcaaaa aaaaaatcta taaatttatt gtagctattg gtgactgtgt
      721 agtaagaaaa aagattataa aaaaattgaa tatgccaagt gagcaatatg gaatagctgt
      781 tcatccaagt gctatagtgg caaaagaaat ttcaattggt tatggaactg ttatttttgc
      841 gaatgctgta attaacccag atgctgtaat tggagagcat gctataataa acacaggtag
      901 cattgttgag catgattgta gaattaataa ctatgttcat ttatctccag gtgtatgctt
      961 agcgggtgga gtacatgtag gtgtaggaac tcaaatagga attggttctc aatgtatcca
     1021 gatgaagaaa attggatctt ggtgtatgat aggcgcaggg agcactattg ttaaggatat
     1081 tccctcacat tccttagctt atggcaatcc agctaaaatt aagaaagaag gaattaattt
     1141 tgaattctag aattttatta tcaagtcctc atatgggagg aacagaagaa aaatatgttg
     1201 ctaaggcttt taaagataat tggatagcgc cattaggtga aaatgtggat aaatttgaag
     1261 aaagtattac aaaatatact ggttctaagg gcggagcttc tgcgttaagt tcaggtacag
     1321 ctgccataca tcttgcctta agactgctta atgttggaaa aaacgatatt gtctttgctc
     1381 cttcatttac ttttatagct acagtaaatc ctattttata tcaaggggct gtaccagtgt
     1441 tcattgactc agaacctaat acatggaata tgagccctgt tgcactagag agcgcattag
     1501 aagaagctga aagaaacaac caattaccta aggcaatcat cgtagtgaat ttatatggtc
     1561 aaatggctga ttatgaacga attttagcta ttgcaaacca atttaatgtt ccagtgatag
     1621 aagatgcagc ggaatcgtta ggttctactt ataagggaat ttcgtcaggc ttatttggga
     1681 caattgggat ctattcattt aacggtaata agatcatcac aacctcaggt ggaggagctc
     1741 tagtgtctag tgataaaaaa tatgttgagc attcaagatt tttagcaaca caagcaagag
     1801 atcaagcacc gtattatcaa catagcgaaa taggttataa ttaccgtcta agcaatattt
     1861 ctgccggtat cggacgtgga caaatggaag tattgaatga tagagtagct aaacgaagag
     1921 aaattttcaa tcgatataag gaagcttttt ctggaattga tagaattgaa atgatgccag
     1981 aagtggatgg catggtgcca aatcgttggt tgtctacttt aacgatcaat gattataatt
     2041 ctattgatca agtagttaac gtaataaata aactaaatga aaaaaacatt gaaacaagag
     2101 ctttgtggaa accactacat ttgcaaccag tatttcaagg ggtaaaaatg tattaccatg
     2161 ataataatct tagtgtgtca gaaaagttat ttaatagcgg cttatgctta ccttctggaa
     2221 gtaatatgac agatagtgaa caagaatttg ttattgatga gtttaaaaaa atattcaagt
     2281 aggtgtgata ttttatgaac ataggaatta ttggtttagg ttccatgggg aaaagaagac
     2341 ttagactcat tcaagaacac tttaatgata ttttactatg tggtgttgat actaatgagg
     2401 cgagacgaaa ggaagttgaa aaggaatttg gaataccaac ttataatagt ctaacagagg
     2461 caaaaaattt gtttgaaata aattcagttt ttgtttgtac atcccctata acccatgaat
     2521 ttattataaa agaggcttta aatttagatt gtaatatctt tacggaaatc aatttattaa
     2581 atgaatatta tgatgaaata atcgaagtag ctaaaaagaa agatagatta ctttatctat
     2641 cttctacatt tttgaagaga aaagaaattc aatatattaa gtctaaagtg acgcataata
     2701 aaaaaatttc ttatcaatac catgtaggac agtatttacc cgactggcat ccttgggaag
     2761 attatcgcaa tttttttgtt tcaaacaaaa aaactaatgg gtgtagagaa atattcgcta
     2821 ttgaattacc ttggattata gatacatttg ggaaagttaa atcgtttact gtaatgaccc
     2881 agaaattatc caatcttgat attgattatt cggacagttt cactcttatt attgagcatg
     2941 aaactggtat agttggaact ttaagtgtag atgttgtttc aagagtagct aaaagaaatt
     3001 taactataat tggtgaaaag attttaatag aatgggaagg taacccggat tctctatttt
     3061 catggaatga agaaacttct agtatgacag atattcaatt gtacgatgag gttatgcatg
     3121 ataataatta ttcacatact attattgaag atgcatattt agaggagatt aaagaatttt
     3181 tcacgctttt ggaaaagaaa atggaacccc aatatacttt tgaaaaagat aagtatatta
     3241 ttaacttaat taacgacatt gaggtaaatt aatgatgaaa gtaatttttt ttgggttagg
     3301 gtcaattgga aagagacatc taaaaaatct aataagctat ggaaaaaaga attctattaa
     3361 ttttgatata acagcttata gtagcagtgg aaaaaaagag tttgaagaaa taacgtatat
     3421 tcaaaataga gacgatttgg atacacatta tgatatagct tttattacaa atccgacttt
     3481 taagcatctg gaaacactaa atgtaattgt tgaaaaagtt gattacatat ttttagaaaa
     3541 acctgctttt tctgagagta ttgatcttac tcaatataat tatgattaca aaaatattta
     3601 tgttgctgct ccactgaggt ataaaaatat catggaagtt gttcgtaata gtattcaaag
     3661 taaaaaagta tattctgtaa gagctatttg ttctacttat cttcctgatt ggagaaaagg
     3721 tactgattat agaaataatt attctgcctt taaatctatg gggggaggag tagaattaga
     3781 ctgtatacat gaattggatt atattataaa cctatttggt ttccctaaat cagtaaaaaa
     3841 acagtttggt aaatattcga atcttgaaat taacagtaat gatttagcaa catatatatt
     3901 gagatacgat gataaaatta tagaaattca tttagattat tttggaagag ttcctacaag
     3961 aaaatttcaa ttgtttactt tagatgaatg tatcaatgtt gacttattaa ataataaaat
     4021 aagttttgaa gaaaacattg ttaaagaaat gcctgaatct gctaatgata tgtatgagaa
     4081 ggagttgaaa tatttctttg aaaacgtagt aacaggcaaa gaaaactgga atgatttata
     4141 tcatgcaaac gaagtattga aaatagctga ggagaaataa atggaaattt tatttactat
     4201 ttgtggtaga gctgggtcta aggggtttaa aaataaaaat ttgaaatatt tggcaggaaa
     4261 gcccctagtc catttcgctt tagcaatgat agatatctat caacaaaaac atcctgaaca
     4321 taattgcacg acttgtttga atacggacag taatgagtta gtagaattga cgactaagtt
     4381 aaatccgtct gtgaaaattg tagaacgtaa acctgaatta gctacagata ctgtagggaa
     4441 aattgaagtg atacgtgatt cattcttaca actagaaaga gaagataata tatttgattt
     4501 aattatagat ttagatttga cttcaccttt acgtgaagtt tctaatcttg aagaattaat
     4561 agatgaacat ctaaaaaatt tagataaaga cgtctacttt tcagttgttt ctgcaagacg
     4621 taatccctat tttaatatgg taaaaagaat tgaaaatgaa gttactatag ttaataaatc
     4681 aagatacaca tctaggcaac agacacctga agtttttgaa atgaatgcct caatgtattc
     4741 ttttaaacct gaatttctaa aaaaaagtaa ttatattttt gatgggcaat gtgggataat
     4801 aaaaatgaga gattatctaa ttttagatat tgatagtgaa gaagatttta aatggttaga
     4861 atttttgttt cctaaatttt tagaagattc ttcggagctt caagatatct ataattattt
     4921 atatcggagg taaaaggatg agctgttatc ttatcaccgg tggggctggc ttcattggtt
     4981 ctaccttagc caatcattta ggagaagaac atgtggtaat cgtcgtcgat gacttatcaa
     5041 tgggaaaagt agaaaatctt gatatgacga aaaatatcac ttttattgag ggagatgtcg
     5101 ctgagaaatc cttgatggaa gagatcatga aagctaataa atttgattat atctttcatt
     5161 tagcagcagt tgctagtgtg gcagattcag ttgcccgacc agtagaaaca catcgtgtga
     5221 attttgaaag tgtattaatg attttagaat tgatccgcaa gtatcaacct gatttaaaac
     5281 ggatcgtgtt tagttcttca gcggctgttt atggggatga accgacttta ccaaaaaaag
     5341 aagagtccgt gattcgccca ttgacgcctt atgcggttga taaattcgct gcagaacaat
     5401 atgtgctaga ttattgtcat ttatatgatg tacccggtag cgcagttcgt tttttcaatg
     5461 tctatggtcc aaatcaaaat ccgaattctc catacagtgg tgtgatttct attctcgtag
     5521 atcgctataa gaaacaaatc gtaggagaag caacttcatt tacattattt ggtgatggaa
     5581 gccagtctag agactttgtt tatatagatg atgtaatcca agcattactt ttagttgcga
     5641 atgaggaagc tgcactgggg aaacaattca atgttggaac gggtaaagca accacacttt
     5701 tggaattgat tcatgcaatc aatgaaattc tcggtgtaga attgacactt gaatacaaag
     5761 aagagcgttc gggtgatatc catgactctc tagcagatat tactaagatc cagtcaattg
     5821 gctatcaacc gaaatatggt attttaagtg gaatgactaa ttatttgaaa actgaaatca
     5881 attaaaacat actaagataa gattagaggg taaattcagg ctctttgtca ataaggactg
     5941 atgagttttg taaaatcaaa tctgggatag aa
//
LOCUS       DACGEU010000126         5922 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.131, whole genome shotgun sequence.
ACCESSION   DACGEU010000126 DACGEU010000000
VERSION     DACGEU010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5922)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5922)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5922
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.131"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..263)
                     /locus_tag="IXR40_002631"
     CDS             complement(<1..263)
                     /locus_tag="IXR40_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362425.1"
                     /translation="MLMEGKTQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINL
                     YYSNKNYFKIPATKTRMKKDVYFLFDIVTDVPDARSDHRRYDY"
     gene            complement(483..849)
                     /gene="ssrA"
                     /locus_tag="IXR40_002632"
     tmRNA           complement(483..849)
                     /gene="ssrA"
                     /locus_tag="IXR40_002632"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(1020..1793)
                     /locus_tag="IXR40_002633"
     CDS             complement(1020..1793)
                     /locus_tag="IXR40_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAQ4362426.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMGNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            1937..2287
                     /locus_tag="IXR40_002634"
     CDS             1937..2287
                     /locus_tag="IXR40_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HAQ4362427.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            2268..2984
                     /locus_tag="IXR40_002635"
     CDS             2268..2984
                     /locus_tag="IXR40_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4362428.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAVVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            2984..4432
                     /locus_tag="IXR40_002636"
     CDS             2984..4432
                     /locus_tag="IXR40_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAQ4362429.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(4503..5012)
                     /locus_tag="IXR40_002637"
     CDS             complement(4503..5012)
                     /locus_tag="IXR40_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362430.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(5002..5727)
                     /locus_tag="IXR40_002638"
     CDS             complement(5002..5727)
                     /locus_tag="IXR40_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362431.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHLQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWHLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
BASE COUNT         2021 a         1029 c         1155 g         1717 t
ORIGIN      
        1 aaatagtcat aacgccgatg atcgctccgt gcgtctggca catcagtcac gatatcaaac
       61 aaaaaataca catctttctt cattctggtt tttgttgccg gaattttaaa gtagttctta
      121 ttagagtaat agagattgat taataagcta tcttcgattg ctaaaaagaa aacttctgaa
      181 tcccacacct tataaaaatc tttgacaaat ctattcgaag gatcaaattt aaaccataat
      241 tgtgtttttc cttccatcaa cataatgttc acctcaaaaa gagtatacga actaatgttc
      301 tttttgtaaa gtaggaatat cattgataat atggatggaa catatatatt aaaaagtgtt
      361 ctttttgaat gctattttga atgccatttt cattcattta acgaaaatct gcgaaaataa
      421 aaaatgctca aacccttata aaataaggat ttaagcatct agcgaaatct gctgaaatct
      481 cacaatggag acggcgggag tcgaacccgc gtccaaacac atcgccactt aaaaatctac
      541 gttcatagtc aactcattta aggattcact ttacagcttg ccgagtgaca ggcattctgt
      601 atcgctagtc tgatgttctc tttttcaact tacagacgga aagttgaaac gtatcccact
      661 aaagttagga cccttactcg agcacatggg cgatgccgag aggatctacg ctaactgttt
      721 ttaggcagct aaagcgtaag agttgttttc gtttttagca gttatattta actgtaacgt
      781 ttttacgtag acgtaaccta cgaaacgcaa ttcaagctcg actgtgcctg tcgaatccgt
      841 aacgtccccg ttagctaaca agggttacgt gtatttttca tacaaaatta gtatagcata
      901 tattgggata aattcaataa aaaagcgaat catatcccat tatttatata ataactgccc
      961 ctttcttaag aaaaaataag cgattttctt aagaaaagag gtagcttcaa aaaaagatct
     1021 taaatcagat caaaatactt caatgcgtgg acaattccgc cttctgtatt tttctttgtg
     1081 ataaaggtag aaagttcttt taatccgtca taggcgttgc ccatagcgat tttgttgtcg
     1141 caagcttcca acaaggcaaa atcattcgga ccatcgccaa atccaaaagt aggaactttt
     1201 tccagctgaa gttctttttg cagacgtttg acacctgccc cttttgagat tcctttcttc
     1261 actgtatcga tcgagtaagg accattccga taaaaagtta gctcaggaaa atgttcgtga
     1321 tagtattcgt cacctgattg agataagatc agcaacatat ttactgtgtt ttctttaaag
     1381 cctaaaggat caatttccgg aacatctgaa tgaatgaagt cgtaagcatt gatcattgtt
     1441 tggctatgac cggtacacca gattttctga tcgttatagt aagaaagttc atgaccgttc
     1501 aactgtacat gatcatacat tttttgacat tcttctgaag aaaatgtttg agaatagatt
     1561 tcttcgccgt ctactcgaat gaaagaacca ttcatggtga ccgcagaagt aatgcccgca
     1621 tcttccatga tagagtggat ttctgcttct gtacgtcctg tagcgatgac ggggagaaca
     1681 ttgttttctt ttaatgcgtt catagctttt gccacttcgg gtgtgatttt tgatttcgca
     1741 tctagtaatg ttccatcaag atcaaagaaa gtgattgcac gataatttga cacaaataaa
     1801 actccttttt tattggaata agtttatctt aacaaagaat gaacaaaaga caaacctttc
     1861 gtgaagaatt cctgaacata ttggttcagt caacaattta gagtatacta taagaagaga
     1921 atttaggagg gaaagaatga tttttttcag tattggtatc ttattcttaa taattggcag
     1981 tctttttcgg attctgccct caaaaggaaa tctgcctttt tatgggtatc attcgcctct
     2041 tgccgcaaaa acagacgctc attggcggct ggctcaaaag acaagcggaa actggttttt
     2101 tcttatgggc ttactgatgg cattgatcgg ctattattta aagacatctg ggcatacgaa
     2161 ttattttctg attgaaatgc ttctgctagt atttccaatt atgcctattt ttattatgac
     2221 agaaaagaaa ttacagaaat atgacctgga aactggaggg aacgataatg aatattttaa
     2281 tgattgaaga taatcaatct gtttctgaaa tgatgcagat gtttttctta aatgaaggtt
     2341 gggaagcaac tttcaagtat gatggaaaag aagggctcga tgccttttta gaaaacccac
     2401 aacattggga tatgattaca ctagacctga atttgcccac actggacggt atgctagtag
     2461 gaagagagat ccgcaaagtt tcaagtactg tgccgattat catgctgaca gctagagatt
     2521 ctgaaagcga tcaggtgatc ggcttagaga tgggggcaga tgattatgtc acaaaacctt
     2581 tcagtcctct gacgcttatt gctcgaatga aagctttgca tcgccgtagt gagttggcag
     2641 aagcaagaga agaagcagta gtttcagatg atcattttga tatcgagact agtcatttca
     2701 agatgaatac gaaaacacga gaagcgtatc tggacaaccg gccaattgaa ggactgacgc
     2761 ctaaagagtt cgatctattg tttactttag caaaaaaacc acgtcaagta ttctctcggg
     2821 agcagttgct tgaattagtc tgggattatc agtactttgg tgatgaacgg acagtggacg
     2881 cccatatcaa gaaattacga caaaaaatcg aaaaggtcgg accacaagtc atccaaactg
     2941 tttggggagt cggctacaaa ttcgatgatt ctggtgttgc ctaatgcgtt atttgtatca
     3001 gcaactctta gctttctgcg gaatggtcgc gttgatctta ttgatcgttg gagtttcttt
     3061 tacacaactg acaaaacaaa cgattgaaga aaacaattac cagcaactgt ttggatatgc
     3121 tgaatcagtt gaaaagacaa cgcaaaccta tgccgatacg ctcccgcagt ttagtcaaga
     3181 tcaggcgttt caaaatgcat tgctgctgac agagcaagta ctgacagaac aaaatgtgaa
     3241 ctttatattt atcgataaaa acgaacgtgt catttatccg actaatacag ctttactgaa
     3301 ttttacctta acagctgatc aatggaaaaa tctgaggaat ggacgtcaag aaaaattcac
     3361 atcgaataaa aatattttag gacaagcaca ggcgacctct tacgcacttg tgccatttaa
     3421 tttgaatcat gaattctatg gagcacttgt agttagtcaa cctgcgcgaa atatcgataa
     3481 cagcgttcgt ccaattacac tgaacctgtt caaaggattt attttttcca gtatcgttgc
     3541 agttattgcc agctatgctt ttgcagcatt ccaagttaag cgtatcaatc ggttaaggaa
     3601 tgcgacgaaa gaagtgacga atggtaattt tgatgtacag ctccccgtac atgacaaaga
     3661 tgaatttgat gagttagcag atgatttcaa taaaatgacg aattcattga aagaatctca
     3721 agcagaaatt gaagaacaag aaaatcgtcg aagacaattt atggcagatg cttctcacga
     3781 gatgagaaca cctcttacga caatcaacgg acttctggaa gggttagaat acaatgcaat
     3841 ccctgaaaat cagcgagaaa acgcgattaa attgatgaaa aatgaaacag agcgtctgat
     3901 ccgtttggtg aatgaaaact tggattatga aaaaatccgt acgaatcaaa tcagtatggt
     3961 cattaaaaaa ttcaatggaa cagaaacatt gaaaaatatt gttgcacagt tagaagctaa
     4021 agcagaagca gcaggagata cattgacatt gaaagccgtt gatgatattg atgtttacgc
     4081 tgattatgac cgatttgtcc aaatcatggt caatattatt caaaacgcga tacagtttac
     4141 tgaaaacggc caaatcacga ttactttaga aaaaggctat cttgaaacga tcatcacgat
     4201 tgaagatacg ggaattggaa tgtctgaaca acaaatgaaa agtatctggg atcgttatta
     4261 taaagtagat ccttcaagaa aaaatacaaa atatggtgaa tcaggattag gtttaccaat
     4321 cgtgcagcaa cttgtacgct tgcataaagg aaaattagaa gtagaaagcg aactaggaaa
     4381 aggaacaaaa ttcgctgttc gtttgcctga cgtagaaatc aaaaaagagt aaaaaacaag
     4441 cggtataaaa gatcatgaat cgatcttcta taccgcttgt tttttactat aaaatgattg
     4501 atttagcccg cgggctctaa acgatcaata taaggacttt gagcaatagt agcatcatga
     4561 gtaaagagta agataccttg attttcttca tgagctaaat aagaaagcaa gtggagtagc
     4621 tcttggatct ccaatacact aagttcatca aatgtatctt caataacaat attgtttcgc
     4681 ttggaaagca aggcatgaag taattgcagc tttacttttt caaaagacgt caactcagct
     4741 gccgcacaat taagcaagga aggagagata tcaagttttt cttgataggc caaacgatct
     4801 tgtttgattt ctttttccgg tacatccaac aggacatggt ctttaagatt cagataagga
     4861 aacatcggcc aatttttttg gatgatcgca aaattatcca gttttgcaac aagaacctct
     4921 tttttcaagt gctccaatat tttatgctgt ttttcgagag gacacaaaat aacggtcaag
     4981 tgttcagcat gaatcaaata ttcaggtttc attacgtcca ggcctcctac tttgcaaatg
     5041 atggataaaa aaagtgaaag ggaatagact aagaatgaga cagcatccac tgagcccaat
     5101 aagagtttgg gcaaatccct taagtatatc tgtgaaaaaa agatcatttt ggaaatcgat
     5161 ggtaaaaaaa gtctgttgat ccatcggaat tgtaagtccg cttaccgaag tcaagatatc
     5221 acggatatct ggcagttcag tagtctttaa gacaagaaaa ttgatccttt gaagaagcgc
     5281 ttcataaact gactggaagc ttacgatcca caataaaacc aagatacaac aaagaaagag
     5341 aggaaagaac agctgccaga aaataaaaag gaataatttg gttttagaaa gaccagtcag
     5401 gtgccaattg atcaattcct gcttgttttg cctgactgaa tagtaaaaga aaaagataaa
     5461 aaggaaggca aatagaaaaa ataaactgaa tatgcctttt atataaaatc ggctagctaa
     5521 ttctaaagcc ggaagaagct ctgtagatgc agaagcgcca ataaatgaaa gccgatcttg
     5581 gacttgattg gctaaagccg attgcaaatg gtaaagagtc aggcatgcta tcaataaaaa
     5641 agcagaaaag cttgaaaata aacaatagag tattgtctgc tttttgtaat aaattaatcg
     5701 agcagtagca tagcggatta ttttcatact tttcacctct ataaaaagta tagaaaatga
     5761 atatgaataa agtatgaaat tcctttagtg aaatcacgaa ttaaaaccag aaaatatttt
     5821 gtaaaaagca agaggttgtg aagaagctgc cctattctat taccgtagat gcaagctttt
     5881 gaacactgtt tattcgaaaa gaggagcagc gacaataatt tt
//
LOCUS       DACGEU010000127         5820 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.132, whole genome shotgun sequence.
ACCESSION   DACGEU010000127 DACGEU010000000
VERSION     DACGEU010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5820)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5820)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5820
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.132"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            24..503
                     /locus_tag="IXR40_002639"
     CDS             24..503
                     /locus_tag="IXR40_002639"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362432.1"
                     /translation="MSRKIDNIILLTTIFYLVIGATLSLLSFLSNSSLIVLNQKSILT
                     EFAHIDYFSFFKTGLICLFLSSFILYIGTTFCLMVLNLKMFIIEKWIVIIAKIFSSIS
                     IIIPMTLTFSKEQFNVATTFVSFIALFSFAVPKTFQSKSSNAKVNVENTDRKNDESY"
     gene            complement(744..1010)
                     /locus_tag="IXR40_002640"
     CDS             complement(744..1010)
                     /locus_tag="IXR40_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362433.1"
                     /translation="MNILSEEFLTRLRIAIVEVVKDALSQLSKKNLSETRYLKKIEAR
                     KYVGGVNDQGFEKLIAHGLKEIRIDGFLRYDKKDIDELMAKYKI"
     gene            complement(1021..1212)
                     /locus_tag="IXR40_002641"
     CDS             complement(1021..1212)
                     /locus_tag="IXR40_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362434.1"
                     /translation="MSNLDNGRAAIKEFMKENGITMDDLATAYGHTRVRMQQILDGHW
                     SGPKANRTILEIIRDYRIR"
     gene            1503..1925
                     /locus_tag="IXR40_002642"
     CDS             1503..1925
                     /locus_tag="IXR40_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4362435.1"
                     /translation="MTTFERIKELAKNKNKNLQQVAKDLKYGENYFYSLNAGKQPTAE
                     KLQEIADYFDVSVDYLLGRTEKKRYYDLTEKDERDIQKELQSLIDDLSNADGMAFSKK
                     DNEMSEATREALIISLENALRIAKIEAKKKYTPKKYRD"
     gene            1942..2364
                     /locus_tag="IXR40_002643"
     CDS             1942..2364
                     /locus_tag="IXR40_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HAQ4362436.1"
                     /translation="MYLPQIDNKINKLVKLYQTRNPFRIARELKILVLEEDLGEIYGY
                     YSKFKQIKMIHINSSLDEMGKWITCSHELGHCVLHPNENTPMLSKKTLVSELKIEKEA
                     NYFATHLTIDPTLDGFDHMTKYEKLVCFGLPDEFDRFL"
     gene            2393..2593
                     /locus_tag="IXR40_002644"
     CDS             2393..2593
                     /locus_tag="IXR40_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362437.1"
                     /translation="MKIGMRKPSIKKSISARTTGKAKRKVKKAVIPGYGKKGSGWIKD
                     PKKAAYNKVYKKTTFSFWDLFK"
     gene            2680..3568
                     /locus_tag="IXR40_002645"
                     /pseudo
     CDS             2680..3568
                     /locus_tag="IXR40_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317363.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
     gene            3706..4911
                     /locus_tag="IXR40_002646"
     CDS             3706..4911
                     /locus_tag="IXR40_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAQ4362438.1"
                     /translation="MAKKEIDKRIKKHLTKKGEEKYQFSLYLGVDPLTGKKRKTTRRG
                     FSTPLAAERALKRLEADIQEKGLQASTAQKSKKFEYVYGLWFENYKKTVKESTWSSTK
                     QIFDTHILKVFGDKFIDKIDVFFCQEAVNTWSDSHPKIFKKIKNYTSNVFDYAASLQI
                     ITSNPMKLVSIPRGEALDIEDKNIEFYTKEELIKFLEAIRNDDDERYLFFSLLAFTGI
                     RKGEAFALTWSDIDFKSKTLNINKTVTRGYQGRLIVNTPKSKSGKRKIYLDNDLISLL
                     RKYYTKNKTIVTIQRENLIFHHDGLLYNPTVSRSWLNVIYKHHPELTKRITTHGFRHT
                     HASLLFESGASLKDVQERLGHADIQTTSNIYTHVTETQNKKVINNFVAFMKNSTQGES
                     KGESKNILG"
     gene            complement(4963..5050)
                     /locus_tag="IXR40_002647"
     tRNA            complement(4963..5050)
                     /locus_tag="IXR40_002647"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5016..5018),aa:Ser,seq:cga)
     gene            complement(5195..5761)
                     /locus_tag="IXR40_002648"
     CDS             complement(5195..5761)
                     /locus_tag="IXR40_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAQ4362439.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
BASE COUNT         2086 a         1014 c          943 g         1777 t
ORIGIN      
        1 tataattctg gtggggtgaa aacatgagca gaaaaattga taatataata ttgttaacaa
       61 ctatttttta tttagtaatc ggagcaactc tttccttact gtcatttttg tccaacagta
      121 gtttgattgt gttaaatcaa aaaagcatat taacagaatt tgcccacata gattacttct
      181 ctttttttaa aactggacta atatgtttat ttctatcttc atttatcctc tatataggaa
      241 ctacattttg tctaatggtg cttaatttaa aaatgtttat aattgaaaaa tggatagtta
      301 ttatcgcaaa gattttctca tcgatatcaa ttatcattcc aatgacattg acgttttcta
      361 aagagcaatt taacgtagct actacattcg tatcttttat agctctattt tcgtttgctg
      421 ttcctaaaac ttttcaaagc aaatctagca acgcaaaggt taatgtagaa aacactgata
      481 gaaaaaatga tgaaagttat taaaaaaaat aattctttca tttattgtca aacctttctt
      541 atagacatta gactttttta gtcagtccct cccgactggc tttttcgctc tgtactcagc
      601 ttcatcaagc ccaatgaaaa tccaaagcat gtaaacgatc gtgccgatta atgcttgtct
      661 actaccccat agacctaaag cgtagataat tagtggcgcg ctgaatacta atgttcgatt
      721 aaactttccc atgttgacct cctttaaatt ttgtatttag ccatcagttc atcgatgtcc
      781 tttttgtcat atcttaaaaa gccatctata cgaatttctt ttaaaccgtg agctattaac
      841 ttctcaaaac cttgatcgtt tacacctccc acatattttc tagcttcgat cttttttaaa
      901 tatcgtgttt ctgacaaatt cttttttgaa agttgactaa gtgcgtcctt tacaacttca
      961 acaattgcaa ttcttaaacg agtcaaaaac tcttcgctta gaatattcat gacttgcctc
     1021 ctatcgaatt ctgtaatcac ggatgatctc tagaatagtt ctgtttgcct ttggtccact
     1081 ccagtgtcca tcaagaattt gttgcattcg tacacgcgtg tgaccataag cagtagccaa
     1141 atcatccata gttattccat tctctttcat aaactctttg atcgccgcac gaccgttatc
     1201 caagtttgac attaacccac ttcctttttt tataaatttg taagttaaaa tgatagaaaa
     1261 aatataattt ccattgacat ttttacacta tagagtaaaa tgaatacata gagaaataag
     1321 cctataacaa aaccttttat ttgcacttgg tcgccaaact ttatgctata aggtgtgttt
     1381 ttagtttgct tttttctatc aaattaactt acggataaat aataactcta tatcgtaaaa
     1441 ttgtaaagct atttttactc tttttcgtaa attatttttt cgtgttggaa aggaacgttg
     1501 gaatgacaac atttgaaaga ataaaagaac tagcgaaaaa caagaataaa aaccttcaac
     1561 aagtcgctaa agatttgaag tacggagaga attactttta tagtttaaac gcaggaaaac
     1621 agccaactgc cgaaaagtta caagaaattg ctgactactt cgacgtatct gtagattatt
     1681 tgctaggacg tactgagaaa aaaagatact atgatttaac agaaaaagac gagcgtgata
     1741 tccaaaaaga attgcagtca ttaatcgacg atttatctaa tgctgatgga atggcttttt
     1801 cgaagaaaga taatgaaatg agtgaagcga cacgtgaagc tctcattatt tctttagaga
     1861 atgctttgcg aatagctaaa atagaagcta agaaaaaata cacacctaaa aaatatcgcg
     1921 attaaaagga gtacgttgtt tatgtattta cctcaaattg ataacaaaat taataagctg
     1981 gtaaaactat atcaaacacg caatcctttt agaattgcac gagaattgaa gatactagtt
     2041 ttagaagaag atttgggaga aatttatggt tactatagta aattcaaaca gataaaaatg
     2101 atccacataa attctagttt agatgagatg ggaaaatgga taacttgtag tcatgaatta
     2161 ggccactgtg ttttgcatcc gaatgaaaac acacctatgt tgtctaaaaa aacgctagta
     2221 tctgaattaa aaattgaaaa agaagcaaat tatttcgcaa ctcatctgac tattgatcca
     2281 actttagacg gctttgatca tatgacaaaa tatgaaaagc tcgtctgctt tggattacca
     2341 gatgaattcg atcgtttctt gtgaattata atacaacgta aggaggatat agatgaaaat
     2401 aggaatgaga aaaccaagta taaaaaaatc cataagcgct agaaccactg gaaaagcaaa
     2461 aagaaaagta aaaaaagcag ttattcctgg ttatgggaaa aaaggtagcg gctggattaa
     2521 agacccaaaa aaggctgctt acaataaagt atacaagaaa actacattca gtttttggga
     2581 tttatttaaa taaaaaaagc ccgtgcagca acacggactc gaaaccttat ttctaagatt
     2641 ccccaataaa aatcatatca tagaaatgag gaataaaaaa tgaaaaaagt aataacaagt
     2701 ttattagttt ttgcttctct gttacttttc actgcttgtg gtaaaaaagt aactacagaa
     2761 gatttaaaag ctaatgattg gttgattgaa gcaaccaaag atgacgaacc taatatgatc
     2821 gtatcatttt ctgatcacgt cgtatctttt agtgttgaca caagttctat gaaatcaact
     2881 tcaagtaacg attgggaggc tatgggagaa gaatttgcta aaagcttagt cgaccaaatg
     2941 aattacaaat ttgagtatac acttgaaggc gatgttatga cttggaaaga tgataaagac
     3001 aaagataatg atgccaaata tactgtcagc aaagaagata aaaatattat tttaactcca
     3061 gaaaagccta acaaatctga tgataatgag aaattagttt tgaaacccta caaaaaggaa
     3121 aaaaactaaa gaatctagaa caactactag ctcaacaagt agcaacgaac aatcatcttc
     3181 gactacaaca gaaagtacta ttgcatcttc tagtactgta gaacaagctg ctattgcgca
     3241 gaatacgcct cctgaaacta gtagtactta ctctgctgaa agtgtagaaa actatgcaga
     3301 agctactcct agttcaagtg ttgaacaagt ttcacccact cccagttcaa cggagcaatc
     3361 agtaccacaa gattatgtac cagctaatca agctcaacca acggcacctt cttcatctga
     3421 aaccgaaacc ttgactttgc aacctggtga agggaccaaa caaatagctg aacgagctgg
     3481 aattacggta gatcaactgt ttgcattaaa cggtatggat ccaaacaact acatgcttta
     3541 tccaggacaa gaactaagag tgaaataaaa aaagcacatt tgccgcccga ccaagaacgc
     3601 aaatgtgcaa agagctacgg taaagtaggt ctatttgttg taccctattt taccatctcg
     3661 aaatccgctg tacaaccgaa caaacgtacg aaaggaaaga taaagatggc aaaaaaagaa
     3721 attgataaac gaattaaaaa gcacttaaca aaaaaaggcg aagaaaaata tcagtttagt
     3781 ctgtacttag gagttgatcc tctaacagga aaaaaaagaa aaacaacgag acgaggtttt
     3841 agtacgccat tagccgctga gagagcttta aaaagattgg aggcagatat acaggaaaaa
     3901 ggactgcaag cttctacagc tcaaaagagc aagaaattcg aatatgttta cggcttatgg
     3961 tttgaaaatt ataaaaagac agttaaagaa agcacttggt cctccaccaa acaaattttt
     4021 gacacacaca tcttaaaagt gtttggagat aagttcattg acaaaataga cgtttttttc
     4081 tgtcaagaag cagtaaacac ttggtccgat agccatccta aaatttttaa gaaaataaaa
     4141 aattacacat ctaatgtttt tgattacgct gcttctttac aaattataac tagcaatcct
     4201 atgaaattag tttctattcc acgtggagaa gctctagata tcgaagataa aaatatcgaa
     4261 ttttatacta aagaagaatt aatcaaattt ttagaagcaa taagaaacga tgatgatgaa
     4321 agatatttat tcttttccct attggctttt acaggtataa gaaaaggaga agcttttgct
     4381 ctgacctggt cggatattga ctttaagagc aaaacactca atatcaataa aactgtaaca
     4441 agaggttatc aaggaagatt gatcgtaaat actcctaaat caaaatctgg aaaaagaaaa
     4501 atttatctgg acaatgattt gatcagttta ttgagaaagt attatacaaa aaacaaaacg
     4561 atcgttacaa tccaaaggga aaacttaatt tttcaccatg atggtcttct ctataaccct
     4621 acagtttcac gttcgtggct taatgtcata tataagcatc atccagaatt gactaaaaga
     4681 atcactactc atggttttcg acatactcat gcctctctcc tttttgaatc aggagcttct
     4741 ttaaaagatg ttcaggaacg tttagggcat gcagacattc aaactacttc aaatatttac
     4801 actcatgtaa ctgaaactca aaacaaaaaa gtcatcaata attttgtagc atttatgaag
     4861 aacagtactc agggggagtc aaaaggggag tcaaaaaaca ttttaggcta aatatacaac
     4921 aaaaaagaca cgatcgaaat cgtgtctaat cgttgatata taaggaaggt acaggatttg
     4981 aacctgcgcg ccggtattag ccggttcgcc ggatttcgag tccggtgcat taccactctg
     5041 ccaaccttcc gtaagtacta tttttaaact tttttcacga aatgtcaagc ctatttctaa
     5101 tagataaata acagaaatcg ctttttttag caaaaaagtc cattgacagt ttgcagccaa
     5161 cggacttacc gatcaaattc atactgatag aacactatct gattatttca ggattatcta
     5221 atgctaaaat cgagtcaatt gtccgtttga tcagtgcaat gatttgttct tctgttggat
     5281 gcatgatgtt tgatgacatc aatgacgcta agccagtcac tgctacccat gtaccagtat
     5341 gcagagcatc gacatattca tccgataatt gattgtatct ttcatcttct ttaactattt
     5401 cacggaaata attgtatgaa aaatcatgca ttttctttcc gtccccatgt tcatcaatgt
     5461 acaatgccat gtaaagacta tgatgctttt ttgcaaagta gatatagttc aaaccgagat
     5521 caatgatttt atcaccagta cgttcaatag ggaaaacatc ttcttttagt tgttcaaaga
     5581 tagaatccag caacgtattt tttaaatctt ccatgttttt gaattccaga taaatcggct
     5641 gtgtcgaaat ccccatcttt ttagcaatat ttctcgcagt aaatccttta aacccttcct
     5701 ttgcaacaac atcataagca gcttttagaa tttgatcctt ggtatagact tttcttctca
     5761 ttaaaactcc cccacttctt tactgcagta tatgttgttt tattgtaccc tatttttagc
//
LOCUS       DACGEU010000128         5567 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.133, whole genome shotgun sequence.
ACCESSION   DACGEU010000128 DACGEU010000000
VERSION     DACGEU010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5567)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5567)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5567
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.133"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(19..414)
                     /locus_tag="IXR40_002649"
     CDS             complement(19..414)
                     /locus_tag="IXR40_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008688205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362440.1"
                     /translation="MKNKGQIWYIGYIVSLFLIVTILVTDFPKMVDIGLAILFSAVFG
                     VSHVQILHDKMIKNDADYKINVMDERNIIIKEKAGNITNMFNTILLGVATVIFICLDY
                     IIPAIIVGSIIAIQPIILIIISSVLEKKM"
     gene            complement(404..616)
                     /locus_tag="IXR40_002650"
     CDS             complement(404..616)
                     /locus_tag="IXR40_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005814946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4362441.1"
                     /translation="MKNRLEELRKQRGIKQEDLASALEVSRQTIGSLENGRYNPSIIL
                     AFKIARYFQMSIEEIFIYEEESEDEK"
     gene            1688..2290
                     /locus_tag="IXR40_002651"
     CDS             1688..2290
                     /locus_tag="IXR40_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362442.1"
                     /translation="MEDIILRDRLTDPLKNSLANVIYDILREADKVYSNYNGKVSWVI
                     YSFLIKEFFKEQINNSYELGYHFTVYYEDIIKRLEDLEWYAYYDLLEVFASAKILDKK
                     KREEVNKILESENSGYRLSESNEFIPITDDISIKSINAVSESPFNYAKNHIHKSLTYI
                     SEKENQDYNTVVREAISAVESCLIEFSGLPANKKILWELL"
     gene            2645..2881
                     /locus_tag="IXR40_002652"
     CDS             2645..2881
                     /locus_tag="IXR40_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003125429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module antitoxin"
                     /protein_id="HAQ4362443.1"
                     /translation="MNIKKRKIREVGNSIVVTLSKESLLQKGLKPGDTIFIDEDKMME
                     AIVKEESKIDLEIDMYVNQALSEYDAAFKELVEK"
     gene            2878..3291
                     /locus_tag="IXR40_002653"
     CDS             2878..3291
                     /locus_tag="IXR40_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HAQ4362444.1"
                     /translation="MIYLSEKDIVKLNVIQIKKYSPRETIGVIDKNALSMAVNQPKQH
                     IFGKDLYPDKFSKAAVLLINLIKKHPFHNANKRTAFLAAYVFLKLNGYSLKMKNQEVV
                     EFVVEIATYQGDFDDLKEATTDILKKNSTKTDSKK"
     gene            3810..4760
                     /locus_tag="IXR40_002654"
     CDS             3810..4760
                     /locus_tag="IXR40_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toll/interleukin-1 receptor domain-containing
                     protein"
                     /protein_id="HAQ4362445.1"
                     /translation="MERNSENKMTGRNPKVFISYSWENKENKEWARELADKLLENGID
                     AYIDQYDLSLGDRLPQFMEQQISDSDYVLIICTPEYKKKANNRTSGVGYEGHIISAEL
                     LSGKNERKFIPIIKEGRASEVLPTFLAGKLGIDLSDSQHYDENLDDLITTIFGVKRKP
                     ALGDIPRHIKGSPLLPIEHNENKDIEILGIITDKVTVPKMDGSRGSALYKIPFRLNRV
                     PSQLWKELFVRNWNSPPRYTTMHRPGIASVVDDEILLNGTTIEEVREYHRETLKLCIE
                     KSNTQEKKILLEEEQKKERENERVRSHKESVQKLADELEF"
     gene            complement(4757..5353)
                     /locus_tag="IXR40_002655"
     CDS             complement(4757..5353)
                     /locus_tag="IXR40_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAQ4362446.1"
                     /translation="MQQNPSIDQNEQRQIEEMRKFGAEKIFIEKQSGATITHRPIFQE
                     VLDFVRDQDIFIVEAIDRLGRNYDEIIDSVNYLKKKNVRLIITNLPIMAEAIGNPLLD
                     KFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANTKDPQRRLV
                     YRSIVQDQENGVAISKIATDYNVTRQTVYRIKKELTIN"
     gene            5414..>5567
                     /locus_tag="IXR40_002656"
     CDS             5414..>5567
                     /locus_tag="IXR40_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HAQ4362447.1"
                     /translation="MNHFKGKQFKKDVIIVAVGYYLRYNLSYREVQELLYDRGINVCH
                     TTIYRWV"
BASE COUNT         1986 a          790 c          949 g         1842 t
ORIGIN      
        1 ttgtatgaac ctttatttct acattttttt ctcaagcaca ctactgataa tgattaaaat
       61 aatcggctgg attgcaatga tacttccgac aataatagct ggaatgatgt agtctaaaca
      121 aataaatata actgttgcca cccctaacag tattgtgtta aacatatttg ttatatttcc
      181 cgctttttct ttgattatga tattccgttc gtccataaca ttgattttgt agtctgcatc
      241 atttttaatc attttatcat gcaaaatttg aacatgagaa acgccaaaaa cggcactgaa
      301 taaaatagca agtccaatat ctaccatttt aggaaaatct gtaaccaaaa ttgtcacaat
      361 caaaaacaac gaaacaatat aaccgatata ccaaatctga cccttatttt tcatcttcac
      421 tttcctcctc atagataaaa atttcttcaa tgctcatttg aaagtacctt gcaattttaa
      481 atgccaatat aatagaggga ttataacgtc cattttctaa agaacctatt gtttgacgag
      541 atacttcaag agcagaagct aaatcttctt gtttaattcc tctttgtttt cgtaattctt
      601 ccaaacgatt tttcacaaca tgctcctttc taaaaaatgg aaagtttact ttcctttcgt
      661 gcttttataa tactcctgcg agcacaaaat gtcaaggaag ctttccatat aaattttgat
      721 tttaatgttt tagttactgt ttttatgaca catgaacaca cttattctta tttcctctta
      781 tctgctatca acagaaaaga aaaagccctg tcaagagccg attagatcaa gccagtcgag
      841 aaacgatgtt agaccaaatt gattttgggt aatgaatgtt tagaacttag tagtcatcca
      901 aaaacgacta ctttttttgt tgaatcgtcc aaggacgatt cgatgctttt gacttgtaag
      961 aacaggattg aatgaaacca tactgttcgc atatttttag tggatgaaca aacaaaatac
     1021 gagagatttt ttgttcgttc atccatggtt ttagaaaaaa gagggacgat tttggaagaa
     1081 gaaaatcgtc tctttttttt cttctttttg tatgacaaaa agaaagatct tttgcccatt
     1141 ttatttttat aaaatgggta ggtggcgttc gcgtaaagca aatcgataca atccaatggt
     1201 tttggcgaat cagatttacc attctaggct tgtttaatac agacatcgat tgttattttg
     1261 agaatttata tccttattgg caatgaaatg gatattctcc ataccaatag aaatcttcaa
     1321 gataattttc ggaaatatat aagagttaat caattatgat catatagtag gtaaaaatta
     1381 ggacagcctt caattatatg ggaaaccaat ataatcaagt aattattcgg gtaacacaaa
     1441 tactagagta ctcatttctt ataactgttt tacacctatt agggatcagt attattaata
     1501 gatctagata aattaatacg taattatata ataatttatg tttgtgccat taaacaatct
     1561 taacagatat ttcattttat ttatgtaaaa caacacgaat aattattgct tcgtaaagtt
     1621 atatgagtat aagttaattt actggaggta gtgcaatgct tttttctgaa agatttggtt
     1681 ttaaaaaatg gaggatatca tactgagaga tagattgaca gaccctctta aaaatagttt
     1741 agcaaatgtg atttatgata tattacgaga ggctgataaa gtttatagta attataatgg
     1801 aaaagtctca tgggtaatat attctttttt aattaaagag ttttttaaag aacagataaa
     1861 taatagctat gagttgggtt atcattttac tgtttattat gaagatatta tcaagaggtt
     1921 agaagacttg gagtggtatg cttattatga tttattagag gtttttgcaa gtgctaaaat
     1981 cttggataaa aagaaaagag aggaagtaaa taaaattctg gagtcggaaa attctggtta
     2041 cagattaagc gaaagcaatg aatttattcc aatcacagat gatatttcta ttaagtctat
     2101 aaatgctgta tctgaatcac catttaatta cgcaaaaaat catatccata aatctcttac
     2161 atatataagc gagaaggaaa atcaagatta taatactgta gtgagagaag caattagtgc
     2221 tgtcgaaagt tgtcttatcg aattttcagg attaccagct aataaaaaaa tactttggga
     2281 actgctataa aagcaattaa agacaaatcg aataacaatg tcgatcttac atttttaaaa
     2341 ccatttgaga caatgtatgg tttggcgagt aataatggaa tacgacatgc agaaaatgaa
     2401 aaaacaattg tctcagattt acctgatgca gttttggtgt taacaacatg ttcagccgta
     2461 attaattatt tgggagtaaa aatagcatat gactccaata aatcatgaaa agttaaaatt
     2521 catccaagag ctacattata actattaatt tccaactctt taaaagttta gtaattgaag
     2581 gaagtaataa gggtgattga acaatacgga tatacggtgt atacttatcg taggagttga
     2641 tgatatgaat attaaaaaac gcaaaatcag agaagtaggt aattcaatag ttgtaacttt
     2701 gtcaaaagag agtttattgc aaaaaggttt gaaacctgga gatactattt ttattgatga
     2761 agataaaatg atggaagcta ttgtaaaaga ggaaagcaag atagatcttg aaattgatat
     2821 gtatgttaac caagctttat ctgagtatga tgcagctttc aaggaattag ttgaaaaatg
     2881 atctatctaa gtgaaaaaga tattgtaaaa ttgaatgtta ttcaaataaa gaaatattca
     2941 ccgcgagaaa caatcggagt cattgacaaa aatgcgctga gtatggctgt aaatcaacct
     3001 aaacagcata tttttggaaa agatctgtat cctgataaat ttagcaaagc agctgttctg
     3061 ctaataaatc tgatcaaaaa gcatccattt cataatgcta acaaacgtac agcattttta
     3121 gccgcgtatg tttttctcaa gctaaatggc tattcactaa aaatgaaaaa tcaggaagta
     3181 gtagaatttg tagttgaaat tgctacgtat cagggtgatt ttgatgactt aaaagaggca
     3241 acaacagata tactaaaaaa gaattcaaca aagaccgatt caaaaaagta gaagcaaact
     3301 agggattcag ttaaatctga agatttagtt tgttctttat tttagtttac ataagataca
     3361 ttatgcgaag ttcattattt taaaagctta aataataaac ttttttataa taccaattta
     3421 tttatgtaaa ccaatgacct taatcgctta agcaagcatg ttatgtaata ctctactctc
     3481 tccaaaacta atgactatct attttcaaag aagctagaat gattatctga tcaaatgata
     3541 atttatattt aattcctggt ctactgctct tcttttaatc aattaatgtc taacgtactg
     3601 tacacgataa agtaggaaga cttattttca acttcggatt cattttttta attcggtgaa
     3661 aatcactaaa ttaagagttt atccaagttc attttagctg agaatacgct tgaaaataat
     3721 tttgatgaat tttcctgaat taaaatttat taacttgttg agtgatataa ttgtaatgta
     3781 ttaccaaata gttagcactt agattagtga tggaaaggaa tagtgagaac aagatgactg
     3841 gtagaaatcc caaagtattt atatcatatt catgggagaa taaggaaaat aaagaatggg
     3901 ctagagaact agcagacaaa ttacttgaaa acggtattga tgcatatata gatcagtatg
     3961 atttaagttt aggtgataga ttacctcagt ttatggagca gcaaatatcc gattcagatt
     4021 atgttctaat tatatgtaca ccagagtata aaaaaaaggc aaataatcgt acaagtggtg
     4081 ttgggtatga aggtcatatt atctcagcag aattgctttc tggaaaaaat gaacgtaaat
     4141 ttatcccaat aattaaagaa ggacgtgcaa gcgaagtact tcctactttt cttgctggaa
     4201 agcttggaat tgatttatca gatagccagc attatgatga aaacttagat gatttaatta
     4261 caactatatt tggtgttaag agaaaaccag cattaggtga tatacctagg catattaaag
     4321 gcagtccttt actacctata gaacataatg aaaataaaga tattgaaatc ttaggaatta
     4381 tcactgataa agtaactgta cctaaaatgg atggctcaag gggttctgca ttatataaaa
     4441 ttccatttag attaaataga gtaccaagtc agctttggaa agagttgttt gttagaaatt
     4501 ggaattcacc accacgatat acaacaatgc atagaccagg aattgcttct gttgtagacg
     4561 atgaaatttt acttaatgga acaactattg aggaagtccg ggaatatcat cgggaaactt
     4621 taaaactttg cattgaaaaa agtaatactc aagaaaaaaa aatattgcta gaggaggaac
     4681 aaaaaaaaga gagagagaat gagcgagtca gatcacataa agaaagtgtt cagaaattag
     4741 cagatgaatt agagttctag ttgatagtca gttctttctt aattcgatac acagtttgtc
     4801 tagttacatt atagtctgtt gctatttttg aaatagcaac accattctcc tggtcctgaa
     4861 cgatgcttct ataaacaagg cgacgttgag gatcttttgt gttcgcactg tataacttag
     4921 gacgtccttt atagacgccg tttgctttag caatctttat cccttgtgcc tggcgtcgtt
     4981 ttgattcagt acgctcttgt tcagcaatca tggccaagat ttgaatgatt aggtctttga
     5041 taaatttatc caggagagga tttccgattg cttcagccat gatcggtaaa ttagtgataa
     5101 taagtcgcac atttttcttc tttagataat ttactgaatc gataatctcg tcataattac
     5161 gtccaagtcg atcgatagcc tctacaataa aaatatcttg gtctctaaca aaatctagaa
     5221 cttcctgaaa aatcggtcga tgagtaatag tcgctccaga ttgtttctcg atgaaaattt
     5281 tttcagcacc aaattttctc atttcctcga tttgacgttg ttcattttga tcgatcgatg
     5341 ggttctgttg caaagttttc caaaaaatct attttagtgt aaaattgaga aaaaagacag
     5401 agaggacaga gtaatgaatc attttaaagg caaacaattc aaaaaagacg tcattattgt
     5461 cgctgttggt tactacctgc gttacaatct aagctatcgt gaagttcagg aattgttata
     5521 tgatcgtgga ataaatgttt gtcatactac gatttatcgt tgggtac
//
LOCUS       DACGEU010000129         5207 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.134, whole genome shotgun sequence.
ACCESSION   DACGEU010000129 DACGEU010000000
VERSION     DACGEU010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5207)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5207)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5207
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.134"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            34..1368
                     /locus_tag="IXR40_002657"
     CDS             34..1368
                     /locus_tag="IXR40_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362448.1"
                     /translation="MDAAFLFSCLYTFATYRTVDIYYRSAIAEAIALTIIPAVLYYAY
                     GLIFNREKKVIALSVSISLLVYTHVLTTLLCSALIACMIIVRLFLSKQIKNDIKFVVV
                     NLVKAVFLTCALTSYFWYPMLQQMNYQEIHSPFKTDLQLEALSISDSIIQALNNDITT
                     YTMGLLGLVALIFPLFILKEMEKKEKIIYVGVVSTWVCVTNLFPWFLFQKTPISLLQF
                     PWRILGIQIFFSSMIITLVFMKKTMNKKYSWLIIGATVVFLLVTSIAAKENYAKVIQS
                     KHGHIVINEETLPRYTTSDMGGLYDYAPTEAIKERPHLEKHEVKVGESWEKGKYKAAD
                     NNITYTVASNKKQKVTVPVYAYLGTQVKVNGKVVNDSYKKHGLVNVDVNAGENKIEIT
                     TKYTPTALMALWISILTYCLVVYSSFKRFAPNKLKDSRYVTKKEINKKNENK"
     gene            1355..2989
                     /locus_tag="IXR40_002658"
     CDS             1355..2989
                     /locus_tag="IXR40_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362449.1"
                     /translation="MKINKKVVILSGLIIVSSIYSFIFFKNTQSIYTTGDLSFHLSRI
                     KGLSTIFTSPINYETFNYTGYGVNYFYPFLTFFPAVMLYWMTKNLIVSYIIYVWLLNL
                     CTTLVAYHYGERFLKQKKAAFLFSCLYIFSAYRTVDIYYRSAIAEAIAITLVIPVLFY
                     AYQIISGKEEKYPSVKLALSMSLLVYSHVLSTLMSTALIIIFIFIRLVSKGFKNADFI
                     AIFKKLFSAAGMTLVLTSAFWYPMFEQMLYQKINKPSVTNLYAHASNVFDSLTEAMNN
                     DLTTYSMGLVGLLSLCIPLILFKKLTNIEKKIYYGTCLTWLATTSLVPWYLLQNTPAK
                     LLQFPWRILSLQIIFSSLILTMIFFKNRRYNKTRELFYLFMTVLLLITLTVSSKKNFN
                     QKIISQPGHIVVNKETVEAYTTKGMDYFLYDYSPIASLENKEHIIKHEAKIGSQWVNL
                     PYKTTGSSIIYRVTNEKSQVITLPVYAYLGTNVEINHQPVKEQVNANGLVQISGVKGV
                     ADIKVSTSYTVTTIISYLVTLTAYLCLFFKIVFHKR"
     gene            3164..3997
                     /gene="msrA"
                     /locus_tag="IXR40_002659"
     CDS             3164..3997
                     /gene="msrA"
                     /locus_tag="IXR40_002659"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAQ4362450.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDIRENISVKEQ
                     LSKLEATLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQGERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
     gene            4077..5066
                     /locus_tag="IXR40_002660"
     CDS             4077..5066
                     /locus_tag="IXR40_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-glyceraldehyde 3-phosphate reductase"
                     /protein_id="HAQ4362451.1"
                     /translation="MYIADSARYEKMEYRKSGHSGLKLPILSLGLWQNFGDYDPIHNQ
                     REILRGAFDMGITHFDLANNYGGPAGAAEKNFGRIFREDFQAYRDELIISSKAGYHMW
                     EGPYGEWGSRKSIISSCDQSLQRMGLDYVDIFYHHRPDPDTPLEETAEALMQLVRQGK
                     ALYIGISNYNGEDTKKMTEILKRKEAPFIIHQMRYNMFSRALLEDDLSPVLEEEGLGA
                     ITFSPLAQGLLTNRYLHGIPEDSRAHRKEIPFLSEEQVGSTLEKIKALQTIAVSRGQS
                     LAQMALAWNLRQKSVTSVLVGASRLSQLQESVRMMDNLDFSPEEELRIDQILE"
BASE COUNT         1825 a          806 c          951 g         1625 t
ORIGIN      
        1 agtttttatt atggagaaaa gttttttaaa aagatagatg ctgctttttt atttagttgt
       61 ttatatactt ttgcaactta tcgaacagtt gatatctatt atcgatccgc aattgcagaa
      121 gcaatcgctc ttacgattat cccagctgtt ttatattatg cttatggatt gatattcaat
      181 agagaaaaaa aagtcatcgc tttatctgtc agtataagtc tacttgtgta tactcatgtc
      241 ttaactacac tattgtgtag tgcattgatt gcttgtatga ttatagttcg tttgttttta
      301 agcaagcaaa taaaaaacga tataaaattt gtggtcgtga atttagtaaa ggctgttttt
      361 ttgacttgtg cattaactag ctatttttgg tatcctatgt tgcagcagat gaattatcaa
      421 gaaatacaca gtcccttcaa aacagatttg cagctagaag cactttctat ttcagatagt
      481 atcattcaag cgttaaataa cgatattaca acatacacta tggggttatt aggattggtt
      541 gcgttgattt ttcctttatt catactgaaa gaaatggaga aaaaagaaaa aatcatctat
      601 gttggcgtag tttctacatg ggtatgcgta actaatttat ttccatggtt tttgtttcaa
      661 aaaacaccga taagcttgct ccagtttcct tggcgtatct taggtatcca aatctttttt
      721 tcttcaatga tcataacgct tgtttttatg aaaaagacta tgaataaaaa atattcatgg
      781 ttaatcattg gcgctactgt ggtgtttcta ctcgtcacgt ctatagcagc aaaagaaaat
      841 tacgcaaaag ttatccaatc aaaacacggt catattgtta tcaatgaaga aacactccca
      901 cgttatacaa catcagatat gggaggatta tacgattacg ccccaacaga agcgataaaa
      961 gaaaggcctc acttagaaaa acatgaagta aaagtaggag aatcgtggga aaaagggaag
     1021 tataaagctg cagataataa cattacttac acagtggcaa gcaacaaaaa gcaaaaagtg
     1081 acagtaccag tatatgctta tttaggtaca caggtaaaag taaacggtaa agtcgtaaat
     1141 gactcttata aaaaacatgg cttagtgaat gtggatgtaa atgctggaga aaataagata
     1201 gaaattacaa caaaatatac tccaactgct ctcatggctt tatggatcag tattctgact
     1261 tattgtttag tggtgtattc aagttttaaa cgatttgcac ctaataagtt gaaagattct
     1321 cgatatgtga ctaaaaagga gataaacaag aagaatgaaa ataaataaaa aagtagtaat
     1381 attgagtgga ttaattatag ttagtagtat atattctttc atctttttca aaaatacaca
     1441 gagtatttat accactggag atctttcttt tcacttatct cgaatcaagg ggttatcgac
     1501 tatttttacc agtccgatta attatgagac attcaattat actggatatg gtgtaaatta
     1561 tttttatccc tttctgactt tttttccagc tgtaatgtta tattggatga caaaaaattt
     1621 gattgtaagc tatattattt acgtttggtt attgaacttg tgtacaacac tcgtagctta
     1681 tcattatggc gagcggtttt taaaacaaaa aaaagcggca tttttattta gttgtctcta
     1741 tattttctct gcttatcgga cagtagacat ctactatcgt tccgcaattg ccgaagctat
     1801 cgcaataaca cttgttatcc ctgtattatt ttatgcttat caaatcatct ctggaaaaga
     1861 agaaaagtat ccgtctgtaa agctagcatt gagtatgagt ttgctagtgt acagccatgt
     1921 actatcaaca ttaatgagta cagcattaat tatcattttt atttttattc gtttggtttc
     1981 taaaggtttc aagaatgcag attttattgc tatatttaaa aaattattta gtgcggcagg
     2041 aatgacattg gttctgacga gtgctttttg gtatccgatg tttgaacaaa tgctctacca
     2101 aaaaatcaac aaacctagcg tgacaaattt atatgctcat gcatctaatg tgttcgatag
     2161 tctgactgaa gctatgaaca acgacttaac tacttactca atgggactag ttggtctgtt
     2221 atctttatgt attcccctga ttttatttaa aaaattaaca aacatagaaa aaaagattta
     2281 ttatggtacg tgtttgactt ggctagctac aactagtttg gtgccatggt atcttctgca
     2341 aaatacgcca gccaaattgt tacaatttcc ttggcggatc ttaagcttgc aaataatatt
     2401 ctcttctctg atattaacga tgatattttt caaaaataga agatacaata agacaagaga
     2461 actattttat ttatttatga ctgttttgtt attaatcact ttaactgttt ctagtaaaaa
     2521 aaatttcaat caaaaaataa tttctcagcc gggacatatt gttgtaaaca aagaaacagt
     2581 agaggcgtat accactaaag gaatggatta ttttttatat gattattctc ctatcgcttc
     2641 attggagaat aaggagcata taataaaaca cgaagcaaag attggcagtc aatgggtaaa
     2701 ccttccttat aaaacaactg gtagttctat catatataga gtaactaatg agaagagcca
     2761 agtaatcaca cttcctgtat atgcttattt aggaacgaat gtagaaataa atcatcaacc
     2821 tgtaaaggag caggtgaatg ctaatggatt ggtacaaata agcggagtca aaggagttgc
     2881 tgatattaaa gtaagcacaa gttatacagt aacgactatt atttcttatc ttgttacatt
     2941 aactgcatat ttatgtttat tttttaaaat agttttccat aaaaggtaaa ttaacttttc
     3001 atttataaaa taaattgatt aaaaaggaga atctgtcgat aaggattctc tcttttttat
     3061 acgaaaaatc tgtaggggga tgaagtaatc gcttatttcc tcactttatg ataaattaca
     3121 gctaaagtca ctagcttgtc ttcttcggaa aggaggagaa tctatggatg aggaacaaat
     3181 attcattcaa acactttata atctgatttt gaatccgaat acacgagatt gggaacgaaa
     3241 agtattgatt cagacaaaga atgacataag agaaaatata tccgttaaag aacagttatc
     3301 aaaactagaa gcaacactac gtccattagc tatccgaatg aatctgacgc ctgatgtaat
     3361 ggacttttat ttattgatta cggaaggatt tgataaggag caaaaatatg acttttccaa
     3421 gcatgccatg caagatgctg actatcaaga acgtgcagta tttgcagggg gatgtttctg
     3481 gtgtatggtc gagccgtttg aatcgaaaaa agggatccta tctgttttgt caggatacac
     3541 gggcggacat gttgaaaaac caaattatga tcaagtaagt ggtggttaca caggtcatgt
     3601 ggaagctgtg gagatcattt atgacacaag agaaataagt tatagcgagt tgctgacaat
     3661 ctattggcaa attactgatc ccacagatac atttggacaa tttcaagata gagggaagca
     3721 atatcgtcca gtgatttttt atcaaggcga acgacaaaaa gaattagcgg aacaatcaaa
     3781 acagaaacta gacagttcag gaactttcca ccaaccaatc gtcacaaaaa tcgaaccagc
     3841 cggtacgttt tggccagcag aaaactatca tcagcaattt tacaaaaaac aaccgaaacg
     3901 ttataaaaaa atccagcaag cacgtaatca atttctgatc tatcaacgag taaaaaacaa
     3961 atggcaaaaa aatatacgaa aaaatcattt tgattaactc cttttcttta aaatgtagta
     4021 aactaaaaat agaaaaaaga aagcgtttta aaaagatttg atgaggagga gaaaaattgt
     4081 atattgcaga tagtgcacgt tatgaaaaaa tggaatatcg taaatccggt cattcaggtt
     4141 tgaaattacc gattttatct ctcggattat ggcaaaattt tggtgattat gatcctatcc
     4201 ataatcaaag agagatttta agaggcgcat tcgacatggg aattacccat ttcgaccttg
     4261 cgaataatta tggaggccct gctggagctg cagagaaaaa ctttgggcgt atttttagag
     4321 aagattttca agcctaccgt gatgaactga ttatttctag caaagcaggt tatcatatgt
     4381 gggaagggcc atatggggaa tggggctctc gtaaatccat catttcaagt tgtgaccaaa
     4441 gtctccaaag aatggggcta gattatgttg acatcttcta tcatcatcgc ccagaccctg
     4501 atacaccttt ggaagaaaca gcagaagctt tgatgcaact tgtaagacaa ggaaaagcat
     4561 tatatattgg tatatccaac tataatggag aagatacaaa aaaaatgact gaaattttaa
     4621 aaagaaagga agcaccgttc attattcatc agatgcgcta caatatgttt tctcgtgcac
     4681 tactagaaga cgatctatct ccagtattag aagaagaagg gctaggggca atcacgttca
     4741 gtccgcttgc tcaagggttg ctgacaaatc gttatctaca tggtattcct gaagattcta
     4801 gagcacatcg taaggaaata ccattccttt cagaagaaca agttggatca actctggaaa
     4861 aaatcaaagc actgcaaaca atcgccgtat cacgaggaca atcattagcg caaatggccc
     4921 ttgcatggaa tttgcgacaa aaatctgtta caagtgtact ggtcggagca agtcggttaa
     4981 gtcagttaca agaaagtgtt cgaatgatgg ataatttaga tttctcacca gaagaagaat
     5041 tgagaatcga ccaaattcta gaatagaaac gatgtaatca aactttttat ccatatatta
     5101 aaaaaaacaa aagatgacat caagaatcga atgaagatcg tctgttattg aacatcatat
     5161 tttttgtcgt tcaaaataaa aatgatcgaa ggctaggagt gaatttt
//
LOCUS       DACGEU010000130         5081 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.135, whole genome shotgun sequence.
ACCESSION   DACGEU010000130 DACGEU010000000
VERSION     DACGEU010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5081)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5081)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5081
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.135"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(41..1081)
                     /locus_tag="IXR40_002661"
     CDS             complement(41..1081)
                     /locus_tag="IXR40_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HAQ4362452.1"
                     /translation="MTDFNFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCSVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFIPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAETESGISIIFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNSE
                     SFPKTITKDWLE"
     gene            2893..3111
                     /locus_tag="IXR40_002662"
                     /pseudo
     CDS             2893..3111
                     /locus_tag="IXR40_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391850.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            3371..3625
                     /locus_tag="IXR40_002663"
     CDS             3371..3625
                     /locus_tag="IXR40_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAQ4362453.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDTIQAKQEGNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            3626..3943
                     /locus_tag="IXR40_002664"
     CDS             3626..3943
                     /locus_tag="IXR40_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAQ4362454.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
     gene            4502..4933
                     /locus_tag="IXR40_002665"
                     /pseudo
     CDS             4502..4933
                     /locus_tag="IXR40_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297423.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(4990..>5081)
                     /locus_tag="IXR40_002666"
     CDS             complement(4990..>5081)
                     /locus_tag="IXR40_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HAQ4362455.1"
                     /translation="GIYKKNRRNGTLFGFSVSTEIKVLMGITA"
BASE COUNT         1761 a          742 c          794 g         1784 t
ORIGIN      
        1 tgctactcca tgaagcaaca atcaatttgt cagtgaaatt tcactctaac cagtctttcg
       61 taatagtttt tgggaagctt tcagaattca aacgtttttc acttgatact ttagcagcta
      121 ttggtttttc gataaaccaa ttttttacat agacaaaaat caggttctgg atattttcaa
      181 ctttttcggt ttttaatttt tgataggctt ttaacagtgt cgtgtataat tcttgttctg
      241 cattgacata ataactatcg agttcttcaa aaattattga aataccactt tctgtttcgg
      301 cttttttctt tgcattatga atagtctgga cagttttttg agcttcactg taacttgaag
      361 aaaatgtttt tattaaattt aatactcgtt cagggataaa cgtagcaatg ctgtcgtttg
      421 tcataattgt ctcaaaattg tctaacaaca attgatcttg taggcggtct ttttcagtgt
      481 ctatattgtg tctattagtg tctaatatat tattattaag ttctggtatg attttcatac
      541 cctctgattt atcaacgttt tggcacggta tgattttcat accctcttga gccccaaggg
      601 attcagcgtc tgatttttcg tcgagggtgg gtatgatttt cataccctct gatttatcaa
      661 cgttttccct attctctcta tcaaattttt cgagtaagta gatatcattt tctgagactt
      721 ttaattctgc tagatatagt ctattaggat tatttttccc taactgtttg ttaaatccca
      781 tctgcttttg taataataaa ccaaaggatt ccaactcttt tttgattgct atcgcttttt
      841 gtttttggca gtttaatacg ctacatagtt catttgtcgt ataagtaaaa taaacattac
      901 cttcttcatc gatttgccgt ttgctgattg cgatctctaa tcttgctttt aaaagcatat
      961 aggcaatctt agttgaatct ttcatttttt tgtattcgtc agaaacaata aagacttttg
     1021 gaaattgata aaataattcg ttgtaaactc tatccgcctt aaaaaaatta aaatcagtca
     1081 ttgtagatcc tctactttca cgttgtttta tttatgtaaa attacctact cttttcgaaa
     1141 atagcaaaga taaataaaaa atgcaaacgc attaaaactg ttttttaatt aaatactacc
     1201 taaaatcaga aataaaatga attatgtact acctttaaag tcattaagaa ctactttaaa
     1261 taaatattat ttataattaa atactaccag aagaacgtat gaataaaatt tagttttaaa
     1321 attaaagata attaagtact accagtgtca aaacaaaaaa taaattaaga actaccttat
     1381 gcatataaaa catactacca ttactagtaa tatatactac cttatttcag tagtatatat
     1441 tatattcttc ttataagaca aggctttagg ctagaaaaca atagattata tactactaaa
     1501 aaatacaata agtactacca atgtcagata tatataataa ttatgtacta ccattaaaat
     1561 taacttattt aataagatac tactgtgtta atctgaaaaa aattacttta aagtagttac
     1621 atactacctg ttaaattaga tactaccatt aatacttaaa ttagatacta cctatattta
     1681 tattaagtac taccgttcta ggaataagat aataaaaaaa aactaccaaa ttgcaattaa
     1741 atactactta aaatgtaaaa aataagaact acccaaatta ggtagttctt aataagagaa
     1801 tatcagataa atttgtacaa gtcataaaaa aattaatctt aaatttttaa atatatatac
     1861 ctgttaatta taaactactt tatttaggta gtacataatt aacagataaa actacatgct
     1921 tgtagtttgt ctagctaatg agttgcatat gatttatata aaggtgtgca gcataactta
     1981 gttgaagtta agagaataga ataaatattt tttgttttgc taataattaa acactaccta
     2041 aatatggtag tgtttaatta tataatattc attttgttac aaataatcgt attataaaag
     2101 cataacaatt gggataacta ttttttagat tatttaagta ctacttaaat taggtagtac
     2161 ttaaattttg gtttaaggta gtaggtaatt aagaaataat atatatcttc ttttataata
     2221 gaaggggaga ggcctagtta aaaacagcga caattaataa caatgtattt aatgcttcac
     2281 aaaatccatt tggtggacaa tgcattgtta ttagcgatga tctaccgttc taagtagttt
     2341 tttctattgg ttgcattcgt gactaattat ggtataatta tgagtaacaa agaggtattt
     2401 cattatatca tcaaacccca tcagcgtgta ggctgatggg gtttttttta cgtttctata
     2461 ttatagaatt aactggtagg cttactgtct tttttggcaa ttttgcaatc aagccacttg
     2521 cagatgtagt gtgcagttac ctctgcaaat ggcttgattg caaaaacaaa atcaaaaagg
     2581 tatttcatta tatctcctcc tccccttgcc agattaggcc ggggtagcag acagcaaaac
     2641 tattataaca taactgaaat acctaaatga catatacaga tatgataatt tatgtattga
     2701 tttttctaac aaaagcacat attttaatat atactaccta ttttaggtag tatatatttt
     2761 tagatacaat atcgatcagt tttgaggaaa tgaaattcta gatatttttt gctacataga
     2821 gttactttca atatttttta acgtaattag gcagaagtca ctcatcctct ataggtttgt
     2881 gatgaaattg ctattgatcc atttaagtaa gagcaaaaaa ctggaggttt atcaggtaat
     2941 tggtctaatg gatttaagta tgcggtcacc gtgtatagag ttgcttatga gattcaagaa
     3001 aataaagtta ttccagtatt gctatatgga acacataaca atttttatga attagccgag
     3061 aacactcgca actttattcg tgtagatgaa tcggcttcgg ttgagttata actttagcta
     3121 tatcaatcaa ccgaccgaca tatgttaaat ctatatataa taaaaatacc tacttaaatg
     3181 gatgttaacg gaagtgtatg gtgagtagtt cactcgtatt ttgatatcgt ttgtatatgt
     3241 tttcagcgtt ctaagtggct tattttgtcc aataataata tggagtggaa tcccttaaga
     3301 aacaccgttg gcaattgtcg ttataacatg ttataattta tttatcaaaa actaaaagaa
     3361 gtgtgataac atgggaaaag aactaaaggt tagaaagatc ggcaatagcg tgggagtgat
     3421 ccttccaagc tctcttggat taaaaagcgg agacactatc caagccaaac aagaaggcaa
     3481 cttattcata ttagatacta ctcaaatagc aaaagaacac gatcgcaaat tgattgaaga
     3541 aagtttccaa gactttgaga aaggtttaac agtttcagaa attgaaatgg taaaagcttt
     3601 cggaaaatac ggctggagtg aatagatgaa agagtacacg ctagtttatt ctaaaagttt
     3661 ccagaccagc cttgaaacga taatagaaga atgggaaaat gagcttgctc tttctccagc
     3721 cagcataaaa agatttgtag gtgcgatcca gaaggcttta gaactaacca aaaattttcc
     3781 aactatgcat gaggaagttt ccgaaatcta tggaatggat atcccaacat atcggatcgt
     3841 gatcggcaaa agctatgcct tattttatcg gatcgaccat gaaaaaaaag agatacttgt
     3901 aggacgtatt ttccaatcta aacaaatgaa actaggcttt taacaataat taggcaaaag
     3961 tcgctcatcc tctacaggtg ggtgattaat gccgctcgat atggttgtta accgtcggtt
     4021 actcgaagat tgatatataa gacttagtac ctttttattt tgctccatgt tatggccgaa
     4081 ggtctaaaga tacaatcatt agtctagaga aaaattaaga accgtaggaa ctacggggat
     4141 cgcttggtga ataagagaca ctgctattag tgaaaaaata agatatcaag tacgctctat
     4201 tcccaaaaat ttcgtgactt tactcatgag aggttcaagt agtatatttt taatcaaaat
     4261 tgacgtaact tttaataaat actacctaaa taaggtagta tttatttttg tgttttaaaa
     4321 gaggaagtcc aatatatcta tgggaaactt cttaaatatt atgttggtac atgaaaatat
     4381 acatccctgc tagactattt acaacatttt actttgtacg tattcttgtt ttaaaaggaa
     4441 tgggataaaa tataggtaca ataactattt gatgctaaat ataattaatg gaggagagat
     4501 agtgaacata cttaatgaaa aaagatatgt atggtttgct ggtaaaaaat atattactac
     4561 tttcaaaaga ttatccgagt taatgcagca gactgttaaa agtgctatgc ctgaaggata
     4621 caagtttaat tttgttcaat cttcagtatc tactgaaagt atctattttt caattctttc
     4681 tgagagtagg ctttttcatt ttagaataag ttctcatgta aagaaaactg atgttgatat
     4741 atatacgttc cgtacaaata attataaaaa tttaaatgat ttgagtagaa gtatcagtga
     4801 atatctcaag gggaatagct atctcaagat tcgattttca catatattaa ttttactacc
     4861 atatttgaat gagaatttca ccctaattca agtagataag tctttcattg cctcaggtaa
     4921 tcaaggaaat atgaaggttc tgttgcgaag tttgaaaatc aaacgcgccc tctctgaact
     4981 ccaaatatct taggctgtta ttcccattaa taccttgatt tcagtagaca ccgaaaagcc
     5041 gaagagcgtt ccatttcttc ggttcttttt atatattcct c
//
LOCUS       DACGEU010000131         5024 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.136, whole genome shotgun sequence.
ACCESSION   DACGEU010000131 DACGEU010000000
VERSION     DACGEU010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5024)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5024)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5024
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.136"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(456..881)
                     /locus_tag="IXR40_002667"
     CDS             complement(456..881)
                     /locus_tag="IXR40_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362456.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DTTNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGTDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKETTVIFTKIGNYRLKDEDGNIYSL"
     gene            1255..2226
                     /locus_tag="IXR40_002668"
     CDS             1255..2226
                     /locus_tag="IXR40_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAQ4362457.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            2258..3655
                     /locus_tag="IXR40_002669"
     CDS             2258..3655
                     /locus_tag="IXR40_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAQ4362458.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHAEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            3814..4437
                     /locus_tag="IXR40_002670"
     CDS             3814..4437
                     /locus_tag="IXR40_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362459.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHDGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
BASE COUNT         1726 a          828 c         1034 g         1436 t
ORIGIN      
        1 tactacgtga tgtagaataa gcctttctat cgtttggtta ttttatattc aaatatttga
       61 aataaataaa tctttactct ttgatttgta aactgaaatg atccactgtt tgttttactg
      121 atgaagcttg atcaaaggaa gaagctgagt ttgaagttca taaaaatcag ccatagtgag
      181 ttttgcttgg atttgtttat cttcttctac tttttacata attttgaaca ggataagatt
      241 caaatgtttt aaatgaatct ttgactagtt tgtgacagtt gtcgcatatg ctcaagcttc
      301 cttggtcatt aaattctgta tggatatttt tgttgttatt acatgtacaa taatcaggac
      361 tatcgatcat ccatttcgtc tcctttacaa tcatcttgct tctttactat agcagaaaag
      421 aaggggagaa acaaaagaag atccaacaga cggcactata gactgtagat gttgccatcc
      481 tcatccttca aacggtaatt accgattttt gtaaatatga ctgttgtttc ttttttattt
      541 tcttttcctg aaataatata ttcgtcatct ttggtagtga tcttgatatc tgtcagcact
      601 gttttttctt cagatgattc agaagaatca gttccttgtg tctgatacgt gcgtgtccat
      661 tccatttttt tatctgtaaa tgtcaactgt cccgcggata aatccatatc tttacgtact
      721 tttagcgtat atacactgtt ggtggtatct gctttttccg cttttaagac agaagaatcg
      781 gttgtttcgt ccgaggattg gtcagagccg ccaaacaaat cacagccagt caatgtcaaa
      841 agtcccgcag acaaaataaa tagtacgatt aatttcttca aaatacttcc cccatttgat
      901 aggataaaga aattatacca ttggaatgta aaacttcaaa cggatggaag agaaaaacgc
      961 acaaaacacc cacaaataga gtaaatttta gaataaaatt ttaaaaaggc aaaaaatccg
     1021 ccactttcag aaagcgtttt aaaaaagtgt tgcaatcttt taaaaaaatg ctatattaaa
     1081 aatgaaccgg ttcaaatact tgtttaagta taattaatag tgagaggaag ttgctctact
     1141 gaagacttta gttatatgga tattgatgac aagcaacact atgcaaagaa tgcggtcatc
     1201 ataatcgaac aacaagaaag agaaatcaaa tgtaactggc aggagtgaga atgtatggca
     1261 tcgatccgtg atgtggctaa gatggctggt gtttcagtgg gaacagtttc ccgttacttg
     1321 aatggtcagc aactgaagga aaagaacatg aaaaaaatag cagaagcgat ttcagcgttg
     1381 gactataaag aaaacatcat tgctaaaggg ttgaagaata atcgaagctt ctctattgga
     1441 cttttgataa acgggatttc cagccgtttt gggtcggaag ttgtctcagg gatcgaaaga
     1501 gtagctgaag aaaatgggta tagcttatta ttaagcgggt ttgccgatca gccagaaaaa
     1561 attgaacaaa aaattgaata cctgatgaag catgtgatcg atgggctgat tgtcttctta
     1621 tccgaagaag agtggtctgg atttgaaatg ctcacaaaaa tgagtattcc agttatcgca
     1681 ttgaattgtc cagaaggacc agcaggtatt gatacaatat tagtgaatga tcgagaaagt
     1741 gtagcaaaag tgatcgctca tcatggtgaa caaggacata aaaaaatcgg atttattgct
     1801 gccactcaaa cagactacgt agcaagagaa cgtttagcag gagccaaaga agcggtccaa
     1861 aatgatccat cgatccaatt agaggtcttt acaggagact attctagaaa aagcggctat
     1921 tacggggcaa aagcattatt agaaaaaggg gcaactgcta tttttgtcag caattacaat
     1981 atgtcgattg gtgccatcga atgtttcaat caagaaggtg tcagaatcgg gaaggatatt
     2041 gcgttcagtc actatgatta tttagataaa aacgatctga gtatccttcc gaaaatcacg
     2101 atcacgccac caacagataa aatcggggaa cgagcagcag aacagctgtt aaaacgaatc
     2161 aaaaaagaag aggaagaaaa tgaaaaagtg attgtgatgg aaaatatcat acatggaatc
     2221 aactaaaacg aactaaaaaa gaaaaagagg tgctttgatg aaaaaatatc aatttccagc
     2281 aaatttttgg tggggttctg cagcaagtgg cccacaaaca gaaggaagga tttcaggcga
     2341 tggaaaagga gagaacattt ttgattattg gtacaaaaaa gaaccgcaaa agttctttga
     2401 tcaagtagga cctgaaaaaa cctcgcaagt ttatacgaag tatcaagagg atgtacagtt
     2461 gatgaaacag actgggcata attcatttcg aacatctatc caatggagcc gtttgatacc
     2521 tgatgaatct ggaacaatca acgaagaagc cgttcgtttc tatcatcgtt attttgatga
     2581 gttgattgaa aacggtatcg aaccctttgt gaatctgtat catttcgata tgccgatgta
     2641 tctgcaagaa aaaggcggat ggttgaaccg agaaacggtt gaagcctatg aaaaatatgc
     2701 caaaagttgt tttgaattgt ttggttcgaa agtaaaaaaa tggtttactc ataatgaacc
     2761 aatcgttcca gtcgaagcag gttatttata tcgatggcat tatccagaag agtcagatat
     2821 gaaaaaagcg atccaagttg gctatcatga agcgttggct tcagcgttag ccatcaaatc
     2881 ttaccatgaa atggagcaag gtggtgttat tggtatcatc ttgaatctga caccaagcta
     2941 tccaagagac gaatcaaacc ctgaagatgt taaagcagcg caaatagcag atgcgttctt
     3001 caatcgttca ttccttgatc cagctgtaaa aggcgagttt ccaagtgaat tgattgagat
     3061 agtaaaagaa cttgatctca tgcctgtgat ccatgcagag gatttgacgg ttatcaaaga
     3121 aaatacagta gatcttttag gtatcaatta ttaccagcca cgccgggtaa aagcaaaaga
     3181 aacaccaatc gatactaaaa acggtccaat gcctgaggat tatttcgaca attatgaaat
     3241 gcctggtcgt aaaatgaatc cttatcgcgg atgggagatc tatgaacaag gaatctatga
     3301 tattttgatc aatgtacgag atcattatgg aaatatcgac tgctttattt ctgaaaacgg
     3361 tatgggtgta gaaaacgaag cacgatttat caaagaagat ggcatgatcc acgatgatta
     3421 tcggatcgaa tttgtccaat ctcatctgaa atatgtccat caagccattc aagaaggtgc
     3481 caattgttta ggctatcata tgtggacatg tatggataac tggtcgtgga ccaatgcata
     3541 taagaatcga tatggcttta tttcagtaga cttagcacaa gatggaaaaa gaacaatcaa
     3601 aaaatcgggt cattggttca aagacgtatc agataaaaac ggatttgagg cttaagaaag
     3661 aatagttgag agcaaatgcg tgaaattctc cattcttacc attttgtgaa aaagaagttc
     3721 aattatttac gatctttttc aacttttttg tctttctatt tcattttttg tatataatag
     3781 aatagtcaaa attaaatagg agtggaggaa agcatgagga aaaaaagacc gtttcttctc
     3841 ttttggttat tcggtttttt cttactgctt attttatccg cagcattttc aggaaaaatg
     3901 acagcagatc ttgctcagaa agaaacagaa aaaatcgtag caagcaaaga atcagtagat
     3961 aatttcaaaa aagaattctc aacttattgg tgggcggagt ataaaataac tgccaattac
     4021 gaaaaaggcg aattggacat ttatttgcca aaaggaaaag aagaaaatca atttattaat
     4081 atcgatgacg tacttagtgc gatttctctc agacaatatc aatttaaaga caagcatttg
     4141 accgttttgc ttttgactca tgatggcgac aaagtagccc gtttgaaaaa tggaaaagtg
     4201 atcaccgctt attctgaaaa agtagacaaa aaagtggtcg ccgatcgttt agcggaatgg
     4261 aaaaagacaa atgaacaagt caagaaaaca actgtctctt ctcaaaaaaa cgagtcgaca
     4321 ggaacaagtc cttcagattc tggcagtgga caaacgataa cgggaagtga agaaaatcaa
     4381 gcctcaatta ttacgaatga gtcatcacaa ggacaatatc aatcctatgg acaatgaaaa
     4441 acagaggttg tgaaatcagc gttttgacct gagtattaga gaaacaaacg gcaaaatagt
     4501 tcctcatatt ttgccgtttt ttgagctaat accgaaggtc agctgattga acaccgtgta
     4561 tcaagaggtc ttgagcctgc cgtttaactc tgagccacaa ggagcaattt caaaaaatag
     4621 ctccttatat ttttcgtttg gttgggctta ttaccgcaga tgcaagcttt tgaacaccgt
     4681 ttaccaagag gttgtaaaat tagcgtcctg acataatcta ataccgaggg tcagctgatt
     4741 gaacaccgtg tatcaagagg tcttgagcct gccgtttaac tctgagccac aaggaacaat
     4801 ttcaaaaaac agcttctcat gttttataaa tattgtgact tgtggccgag gagttggcag
     4861 gagaacaccg tttaaggaag aagttgtgaa aaagctgtcc tgcatcaaga aataaggagc
     4921 tgcgacaaga attttgtcac agcctctttt tttgtacgaa taccgagaaa ctggcttttg
     4981 aataccgtgg agtgaagcgg tcaccacaag acttttatct cttc
//
LOCUS       DACGEU010000132         4932 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.137, whole genome shotgun sequence.
ACCESSION   DACGEU010000132 DACGEU010000000
VERSION     DACGEU010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4932)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4932)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4932
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.137"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(225..1112)
                     /locus_tag="IXR40_002671"
     CDS             complement(225..1112)
                     /locus_tag="IXR40_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAQ4362460.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(1109..1978)
                     /locus_tag="IXR40_002672"
     CDS             complement(1109..1978)
                     /locus_tag="IXR40_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAQ4362461.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(2115..3401)
                     /locus_tag="IXR40_002673"
     CDS             complement(2115..3401)
                     /locus_tag="IXR40_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HAQ4362462.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            3674..4932
                     /locus_tag="IXR40_002674"
                     /pseudo
     CDS             3674..4932
                     /locus_tag="IXR40_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292017.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
BASE COUNT         1531 a         1013 c          838 g         1550 t
ORIGIN      
        1 caatcaggac agtcatcggc aatatagcag caatcacttc tttaaaattt tttagcatgt
       61 atcctcctcc tttactcttt aagtttacct taaaatgaaa gagttttcga gcacaaactt
      121 aaaacgttat catttaattt ttctcaacat aaaataacac acgtcccaaa agtatctttt
      181 tacttggaaa aatgactttg aaggaacgcg cttattgtgt ttttttattt tacagagccg
      241 atcattcctt gaacgaattg cttttgcaaa acaaaaaata cgatggcagt tggtaaagta
      301 gcgatgacta atccagccat gatcattcca tagtctggtg tataggaagc acccatagca
      361 gataaaacaa gcggaaccgt ccgtttatca ggagattgca aagctactaa gggccataaa
      421 taattgttcc agctactcat gaatgtgatg attgcagccg cggcataggt atttttagcc
      481 gtcggcatat acactctaaa aaaaatactt agttctttta gaccgtctaa tcgagcggct
      541 tctactagat cttttggaaa agatttaaca ttttgtcgaa agaagaagat caaaaaagca
      601 gtgctaacag atggcaggat gacaaccaag aaactgttga ttcccaaaac cgttccgttc
      661 aattgtgaaa acattcgata taaagggatc atcaatgccg caaaaggaac catcatcgat
      721 agcagtagaa tattgaaaat taggtctttt cgtttacttt gataaatctc aaatccatat
      781 cctgccattg acgaaatcag caatgcaaac acagtggtca ccaaagcgat catcgctgaa
      841 ttccaaaggg aacgagtaaa attcagctca ttggaaaaca aattttgaaa attgatgatc
      901 aagttactgc caatctttat ttttcccgat gtgatatcca cgggtgtatt cgtcattccc
      961 aaaaccatcc agacaaaagg gaaaatggaa ataaatgata ggatgcttaa tgctgtatac
     1021 tttaatactg acccaattgt cgaacgaagt tctaatgctt gttttttgac gttggggcgt
     1081 tcgattgttt ctttttctac catatttttc atcgactttc tcctcctact ttcgtttgga
     1141 ttatcgacaa tatcacaata aaggaaacaa taacaaagga aactgctgcc gcatatccaa
     1201 aattaggcgt gaatttataa ctcaaattat agatgtattg agatagggtg gtcgttgcat
     1261 ttgctggtcc cccgccagta atattttgta cttcatcaaa aagctgcaat gtcccgatcg
     1321 tcgaagtaat ggaagtaaac aaaatgattg gttttaaatt tgggatcgtc actttgataa
     1381 actgctgcca tttagaagca ccgtcaatag atgctgcttc ataaatctcc gaatcaatat
     1441 tttgcatgcc tgaaaggaaa aaaatcatat tgtatccagt ccaacgccaa gtgatcgaaa
     1501 gaatgatcag aactctcgcc caaattggat gagtcaacca gccaatcggt gtgtcaatca
     1561 taccaatgcc caacaacaag ttgtttacaa ggccagattg agaaaataga cttttcatga
     1621 tcagagaata actgaccatc gaagtgatac atggaagaaa gatagcggtt cgaaacaacc
     1681 ctttatattt caacttttta tcatttaaaa ggttggaaat aaaaagtgct agaaacaaca
     1741 tgatcggtac ttgtacaagt aaatacagga atgtattaaa aaaagctttt ttaaaagttg
     1801 catctgtcaa catccgctga taattaccta acccgttaaa tgtcatattg acagggggac
     1861 cactttgaaa agacgtgatc aaagccaaaa ccatcggaat aaaaaccatg attgatatca
     1921 aaatgactgg caagattaaa aaagcatgcc cgtttttgaa taaatctttc tgcttcattc
     1981 ttttccctcc aattctatca ttgattatct acatgaaaag acaagaaaga caatatctgt
     2041 aaggcagacg tgatcttttt tgtcttttcg tttgtctgat gaaaaagcga agaaattcac
     2101 ttttttacca ccgatcaatt agccaattgt gcttctactt gtttttgtgt atctgctagt
     2161 accttgtctg tctcttctcc attgatgatt cgatgaagag cttcagctac gactgcttca
     2221 attgcatagg tctcatgtcc gtaattcact tctggtattt cagatgtcca tgttgaaaaa
     2281 tcgtcaaaga tcttttgacc actgtaaaat tcagaagctt cttgataagc ttcttgttca
     2341 ttcgcgctaa gcatcgtaga tactagtccg atttctttcg caagagtgcc catcagttct
     2401 tcattcgaag caaacgttgc ttctaggaaa tctttcgctg aatcttctcc agctactcct
     2461 ttgatcacat accagccagc gccgccaagg ttagaagctt gcgctttttg cagattttct
     2521 ggaagtgcag gtattggtgc aatcttccat tttccagatt ggttttctgc tccttggatc
     2581 gttgaagaat accaagcgcc agttgggcta gaagctactg ctcctgattg tatcgcagtt
     2641 actccagcat tccagtcaga ggtttgttcg actagatctt ctttcaaaag agtggcaaac
     2701 aattcaagac catactttaa agatgcattg tcttggatcg tgactgtctc cccatcttca
     2761 gatgtatacc attctcctgc ctgttgcata atcatcctta ctcgaccaag gtcagaagga
     2821 ttgacttcag cgattttctt tcccgtcttt tctttgacat ctcgcgctac ttgaatatac
     2881 tcgtcccact tcagattctc catatcctct tctgtataac ctgcttctgc catcagatcc
     2941 gtacgataga agtttgctgt tacgcccgaa tcgaaaggaa caccgtatat tttatctcct
     3001 actttgttta ccgcaaattt atacggtgca aaatgatctt cctttacaat agcagacaaa
     3061 ttagcgaatg catctggata agaagtcaaa tagccttgta tcctataatc ttcaatcaag
     3121 acgatattgg gcaatccttc tgtattcccg ctcgctaaag cggtgttcag tttctgaacg
     3181 atatcatcct gagacatcgt aacaacttct atctctgttt cttcgttctc ataaactttt
     3241 tttgcttcat tcactgcttt gatattgaat gtctcatccc acgcccagac agtgactttt
     3301 tcttctttgt ctgctgtact actagcactt ccgcatcctg ttaagaaacc tgatgctgcc
     3361 gctaaacaaa cgactccagc aattaacttt ctgatgttca tttttatccg ctccttttcc
     3421 atccattagt tgtttacgtt tgctacattc atcataccaa aatttgaaaa cggtttcttt
     3481 attattcaga tacttcaaaa atttctccta aaataataaa aaaatacaaa tcaactatga
     3541 caaaaggaat aatcttagca tctagaccaa agatcgaaat ggtgaggttt ctttaaaata
     3601 aaaatatcct tgcattttct cctagaaata agtattttta aattacaaga ctattcttaa
     3661 ggcgggtaaa aaaatgccaa tacgcgtaat tcttatcgat gatgaacaga cgattttaga
     3721 tggaatgaaa cagttgatca attggtctga gcacgggttt caattaatag ggactttttc
     3781 cagtccgctg aaagcgcttg atttttcttt ggtacatgca atcgatatcg tggtcacaga
     3841 tgtaatgatg cctgaattaa atggaatcga attatcgcgg ctattaaaac agcaacaacc
     3901 tgaaacacag atccttatcc tctctagcta tgatgaattt gatatggtta aagattcttt
     3961 taaagaaggc gtcgctgatt atcttttaaa gcctcgattg agtcctgatt tttttctaaa
     4021 ttccttaact gccgtttcac aaaaaatcaa aaaaaagccc aacaaaagcc caatcaccaa
     4081 tcgttatgag cagatctgcg agaatctttc acagcagatt gctggacaaa ctcgtccatt
     4141 gcttgaccct cttctttttg aacacacctt gtttttctgt tatataccga aaaacggcca
     4201 ttcagttcaa aacaaggctc taaacaaaaa cagtcgatca cccattcatt gatggatagc
     4261 gacgattcgt ttactattta tcctgtttct accttttcgg aagaatccgg ctatgtaatc
     4321 aatactgatt ccaaagatac acttaggaag tttgttcaaa agtttcgtca agaagttttt
     4381 ccaggtgatt tttttgttgt ttctgattct tttgcaatcc aagatatcaa tgaaatattc
     4441 caagagatca gaaattgcac caaaggacaa cgtttctatc ataagggaaa gaaccttgct
     4501 tatcagcatg aacttcttcc gttattaacc aaccacgagc agcaagcaag tagttattta
     4561 acaaaaatcg ttcataaaga ctacgcttta gctgtcaaag aacttgagaa tttcttcacg
     4621 acgatattgg aacagcctat tgatccagct tatttgaaac atgaggcaat caatcgtttc
     4681 tatgcattac tcaacgcttt ggctgacgag catgttggga atgaagaact ttctttgctc
     4741 aagatcgccc ttccttcttt attagccgat gctgagtatt tcgaagattt ttctattctt
     4801 gtcaaagaaa cacttgagaa actcacccac ttttctgcaa atgcaaaaaa agacaatttc
     4861 gatatcttga ctttgatcta cgagttcgtc caggaaaatt atgagaaaga aatcaattta
     4921 caacttttat cc
//
LOCUS       DACGEU010000133         4796 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.138, whole genome shotgun sequence.
ACCESSION   DACGEU010000133 DACGEU010000000
VERSION     DACGEU010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4796)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4796)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4796
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.138"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(82..1890)
                     /gene="pepF"
                     /locus_tag="IXR40_002675"
     CDS             complement(82..1890)
                     /gene="pepF"
                     /locus_tag="IXR40_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HAQ4362463.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
     gene            complement(2066..3064)
                     /locus_tag="IXR40_002676"
     CDS             complement(2066..3064)
                     /locus_tag="IXR40_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HAQ4362464.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            complement(3290..3943)
                     /locus_tag="IXR40_002677"
     CDS             complement(3290..3943)
                     /locus_tag="IXR40_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HAQ4362465.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
     gene            complement(4275..4673)
                     /gene="spxA"
                     /locus_tag="IXR40_002678"
     CDS             complement(4275..4673)
                     /gene="spxA"
                     /locus_tag="IXR40_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HAQ4362466.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
BASE COUNT         1406 a         1007 c          744 g         1639 t
ORIGIN      
        1 taaaaaaata cgtcgactcc cttacaagag agccgacgta tttttttcgt ttctattcga
       61 gaaaatcaaa aatagaaagc cttataaacg atcgatcaat tcttctaatt catttagacg
      121 ttgttcaaac atcgacattg catcttcaat atatgcagcc tgtgtcatat caactcctgc
      181 ttttttcatt acttccacag gataatcgct gttacctgct tttaggtaag ccaagtagtt
      241 ctctagtgcc tctggttcct ggtttagtat tttcttcgcc agtgctgaag cagcagaaaa
      301 gccagtcgag tattggaaaa catagtaatt ataataaaaa tgcggtatcc gtgaccattc
      361 gaatttaatt tctgggtctt cttcgactgc tggaccataa tattttgcat tcaatttacc
      421 ataactatca cttaggtatt cactagtcaa tggcacacct ttttcatctt ccgtatgcat
      481 gaaatgctcg aattcagcga attgtgtctg gcggaaaact gttcctttaa acccatccaa
      541 gtaatggttg agtacataag cccgtacacg agggtctttt tctgtttcca ataaatactc
      601 cgttaggata ttttcattcg ttgtcgaagc aatttctgct aaaaagatgg agtagtcgcc
      661 gtacacataa ggctggttcg aacgagtgaa ataactatga acactatgtc ccatttcgtg
      721 gacaagcgta aatagctgat ccagcgtatc atgccaattc aataaaatat atggatttgt
      781 gtcatagctt cccgaagaat aagcaccgct tcgtttccct ttattttcga caacatcgat
      841 ccaacgttca gagaatgctt tttctacgat ggccatgtat tcttcaccca ttggtttcag
      901 tgcttctaaa gctttttctt ttgcttcttc gtacgtaaag gtaattggag cttcccctaa
      961 gaccggtgta taaagatcat acatgtgcag tttttccact tctaataaac gtttccgtaa
     1021 ttccatgtat cgatgtaaca aaggcaaatg cttgtttacc acgtctacca aagtatcgta
     1081 tacactttca ggaatatgat tattgctcaa agacgcttct ctggcagagc tgtaattacg
     1141 gactttcgct ttaaaattat gtccttttat atgtgtgcct aaagtagaag caaatgtatt
     1201 tctaaattgt tcgtaaacac tgtacaaccc cttaaatgct gcttcgcgca cccttcgatc
     1261 cgtgctttct agcaactgac catacacgcc atgagataat tggactattt caccattttc
     1321 tccttcaatc gttggaaaaa ctagatctgc attattcaaa acagcaaatg tatcacttga
     1381 agcatcaaag atttcacctg ctccagcaag aagagattcc tgctcagcag ataagacatg
     1441 ggctcgatta tctactattt gctggatata atggcgatag acttccaatt ttggttcttc
     1501 tttgaaatat tgccaaatct ggtcatctga caattgcaat atttctggtt caaaccagga
     1561 aacggcttca ctaactttcg aaaacagact gcttgctctt gcataaagcg cttggtaatc
     1621 tgtatttcca gtgtcttgat cgtttttaag gtgcgcatat acataaatga cttcagtttg
     1681 gcgataaacc ctcaatacga attcaatcgc atttaaaaat tgagaagcgc cttgatcaag
     1741 tgttcctttg tgtttttcag attgttttaa ctcttctgat aattccaaat atttctcatc
     1801 aaactcttgg tcgcttgaaa agatcttggt caagtcccaa gttaaatttt caggcaattc
     1861 ttctcgtttt ggcaactgct ttacttccat gaaatccact ccttttcttc ccttagctct
     1921 atctatcaaa atagatcata gtctaacatc cacatgtcac agcatctaac ttttctactc
     1981 attcatgtgt ctgcttccat caattttagc ataactaaat cttgttttac atagaaaacc
     2041 gattcctagc ctatttttat acttactatt ttttcaaaga agacaagtgt atgcattcgt
     2101 taaaaaactg ctgatagacc atctcttcat caatcatagg aaaaagccat tcccttttat
     2161 gttcttttat ttggcaaagc catgagttga aatcaggaac tttctggttt tccaaggctt
     2221 cttcgtacaa cattcgataa agaaaaacct gttcttgtaa ataaaagaaa aaccgacttt
     2281 tttgatagat ccacgatgat agatgcaaaa gatgtttatg acgcaagtag cattgttctt
     2341 gtatggatac tgtattcttt tgcttgtgaa taagttggcg tgtcagccat ttcttcccat
     2401 cttcactcac tttttctatt tttttcattt ggttcatttt aatttcgtta ctagtgaata
     2461 tttctttaag gtccctacta gaaaaagtcc agcagctact gcaaaaggaa atatgccctg
     2521 atacagtctc tgtaatatga tgatacaaat aaagcttttg tttcttgaga tcagctttcc
     2581 agcaatgcac tcctcttttt ctattatagt agcagcaact tttttctatc aatgagaatt
     2641 gcgattgtcc aagaaaagaa ttaccaagta tccaccatac ttggtaactg ttattcaaat
     2701 aattttgggt tctttcaata aatctctggt gagacagtct agaacattgg atttctattg
     2761 ctagattcgc caacaaaata tccggccttt gccgcaacct cggcaaatag gcttccaaaa
     2821 atactggttc tactgactgt cccagccaat ccatgaagca ttcctttaac tgtaagtgct
     2881 cttttgattc tctttcacta aagaccgaac agttatctga tttttgatgg gcaaaatgag
     2941 cacatttttt ctttcccttt ttcaaaatca ctctttttcg acagccacga caataatatt
     3001 tctttccttt ttctgcatgt ttagcaaaac agcacttatt atattcattc attgcaagca
     3061 gcatttttct ccctctgaac ttatttacgt ctaagaattt atttacacga aaaaagaggg
     3121 cgtgaaaaag ctattctgca tcaagtaata agaacagcta aacaaaaata gttcccaata
     3181 tttttcgttt ggttgggctt gttaccgcag atgcaagctt ttgaacacat ttatacgaaa
     3241 aaaagactgc gacacaattt ttgtcacagt ctcttactat aatgctgatt tatacaaaat
     3301 aaaatttcgt tcgctcgata gcattacgcg ccatcagaca ttgtccatat tcattcaatg
     3361 tttctggtgt acgatcgctc ttttcagcaa actccaaaat tcgagcaatc tgattctcta
     3421 catccgcttg gttgagattt tccatccaga agtgaacgac taggtaatag cgctcttcga
     3481 ataaatacaa atcagtccaa gcagactcta gttcgacatc tgttgcaagt tggatcactt
     3541 gttcaaaatc ttcaaaagca aaagttgctt gtctttcctg ttcttctagg gcgcttccag
     3601 ataattcttc ctccggatcg ctgccaataa tctgctgacg aagaaagtca ctcacatctt
     3661 ctgaatcaac agtagaatct tctgattgag aaatttcttc atccggaaga tttttactga
     3721 taaacagttc taatccgtct ccttttggca aaacttggaa agtgacagct tcgcttcctc
     3781 ggaactcctc ttcgatatca acttcttcca aaatactata aaagaaattt tcgatttctt
     3841 tgtgattgcc aagtaaatcc aaaaatgaaa cgccccgttc ctctaaatct tcatgaccaa
     3901 ttagtacacg gatcgtattt tcattaatat gttccatttc cattttgcta cacctcactt
     3961 tgccacaatg tttaatatag attcattgta gcgaaatcag cttaaatgta aagaaaaaaa
     4021 atctcgctgt taagcgaatt taataaaacc agcggatttt tcaacctttc aagctatctt
     4081 atttaactat aacatttttg gcagacgaat actatatagc cgacttttca gctaattttc
     4141 cctctctatt tttcgtgcaa tcatcatctt ctactacctt tttatacatc taatcaagaa
     4201 tactttttgt aaaaacaaaa aaacttggaa aaactatctt tgtaatagtc ttttccaagt
     4261 ttcgtattat ccttctataa tccagccatc aattgtgctt gacgtaattc taattgtcgt
     4321 acatcgcgcg gtaggaaccg acgaatttca tcttcattaa aaccaacttg cagacgttta
     4381 tcatcaatca tgattggacg gcgaagcaat ccaggattgt tttgcacaag ttccaataat
     4441 tcttgtaacg gcagatcatc taaatccatg ttcagttttt ggaatacttt ggaacgtgtc
     4501 gagatgattt cttctgttcc gtcttctgtc atttgtaaaa tcgcttttaa ttcagaactg
     4561 ttcaatggtt ctgaaaaaat attacgttca acaaatggaa tctgatgttc ttgcaaccac
     4621 gcacgagcct ttctgcagga agtacaactt ggggaagtat ataatgttaa caacgtgcac
     4681 cactcctttt cgtgataaga atcacttttt tgtaacagaa gatcataata atctcccatc
     4741 tgtttctatt atacataatc aacttttaaa tagctacctt tttttcataa tttttt
//
LOCUS       DACGEU010000134         4752 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.139, whole genome shotgun sequence.
ACCESSION   DACGEU010000134 DACGEU010000000
VERSION     DACGEU010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4752)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4752)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4752
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.139"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(73..1221)
                     /gene="nagA"
                     /locus_tag="IXR40_002679"
     CDS             complement(73..1221)
                     /gene="nagA"
                     /locus_tag="IXR40_002679"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HAQ4362467.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            complement(1297..2133)
                     /locus_tag="IXR40_002680"
     CDS             complement(1297..2133)
                     /locus_tag="IXR40_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4362468.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            complement(2317..3534)
                     /locus_tag="IXR40_002681"
     CDS             complement(2317..3534)
                     /locus_tag="IXR40_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAQ4362469.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            3917..4000
                     /locus_tag="IXR40_002682"
     tRNA            3917..4000
                     /locus_tag="IXR40_002682"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3951..3953,aa:Leu,seq:gag)
     gene            complement(4240..>4752)
                     /locus_tag="IXR40_002683"
     CDS             complement(4240..>4752)
                     /locus_tag="IXR40_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362470.1"
                     /translation="YYVRILTALPFFLNLIIYFGNTMGQSFTYVNGNKRAMIWSSSNL
                     NNLFTELGTKLSLFYPGTWIATLVVLALLLCLIVGIYLSFDNKKTSIFLVILMIMGFC
                     SRLIMGFSPTVWASGMRTYYILYVVIAILVLMAVKELMKSMSVQKNEFMQFGLTVLGI
                     CTFIITVINR"
BASE COUNT         1436 a          998 c          766 g         1552 t
ORIGIN      
        1 ttttactaga acacaaaaaa aaccttaaaa ccaaacttaa gaagtttagt tttaaggtta
       61 acttaaatta tattatgcgt ggaaacgttc cacgccatct agataagttg cttccaatgt
      121 catatcaggg ttcaatacga taaagtctgc atcgcgtcct tgagcgattt ttccacatgt
      181 atcatcgatt ttacagctga ttgctggaat cagactagcc atcatgactg cttgttctgg
      241 tgttgctaat ccccagtcta caacattttt aattgcttct ttcaatttca atatacttcc
      301 agctaagttg ccagattcta gacgtgctgt tccttctttt actactactg gaaattcgcc
      361 taaattgtaa tttccatcag gcatcccacc ggccatcata cagtctgtaa ttaatgcgac
      421 atgatcatgt cctgcttttt ccattaggat tcccgcagca tttggatgta catgatggcc
      481 atcacaaatc aattcagaaa agacatgttc taaagataat aacgcaccca ccatacctgg
      541 ttcgcgatga ttcaatccac gcataccatt gaaagcatgg acaaatacac ttgcgcctgc
      601 ttcaacagct ttttgcgctt cttctagtgt agcattactg tgtcctagag aaacaactac
      661 tccttcttca gtcacttgtt tgacaaactc ttctacacct tgacgttccg gtgctaaagc
      721 aatttttttg attaaaccac ctgaagcttc ttgccattca tggaaagtat ccaaatcagg
      781 atccccgaaa taacttgggt tttgtgcccc tttgtgttct tctgtgaaga aaggaccttc
      841 aaaatagatt cctttgattt tagctcctgg tgcttcctga tacattttgc cgattgtctc
      901 agctacatct tttaaacgtt ctttgcttga cgtcaatgtt gttggtaaaa atgaagtcac
      961 tccacaagat aacagacctt cagacatcac tttgatgcct tctgcatcat tatccattac
     1021 atcatgattc atatagccgt gaatatgtgt atctaccaaa ccaggagcaa tccatttgcc
     1081 gctttggtca atgatgttga cttctccctc aggtagttct ttggtgtatt caccaaaaag
     1141 tccatcggta atttcaagat agcctgcatg tttgacacct gacgctaaaa agaatttgtc
     1201 agcatagata aaagttctca ttctattctc tccctttgtt tttctacctc taaagtactc
     1261 ttatttagag aagaagtcaa gaatggtcta caccatttac aaattttttg aaatttgttt
     1321 cacagcttgt gctaagcctt catagaatgc tgctctttct ggttcttctt tacgcttgta
     1381 tattaagctt ttaagcacaa ataaatcatt gaggtaatag tagctattct tctcttgagc
     1441 ccaatagatt ccttgattca cctgttctaa cgcttcgtcg atttcatttt gatggaataa
     1501 gaaatttcca taattataaa aaatttgcga aaattcactt tttgatcgtt catcagctga
     1561 ttgatgcagc agttggatgc ttcgactcaa atagtagcgt gcttcagccg tttttcctgc
     1621 cacaccatat atttttccga tacaactaat cagttgtatt tctgtgtcag aaacatggat
     1681 tctttctttt tggctagagt agcttaatgc ttctttcaaa taataaaggg actgagagat
     1741 attttgacgc aacgtgaatt cgcaaacacc gagataataa taatagcgtt gaaagtcagt
     1801 tgcttgatac agattttcag aaatatcaga agattttagt acttgttcta acttccgata
     1861 atcacgtttt tggaaacaac tatccaacag ttcaaataat ttatcgtttg tccgagtagt
     1921 ttttcgagag agattcatca catgatcaat cgttacccct agccgttgac aaatctgcat
     1981 catcaccaat acattcggca gttcctcatt attttcgatc cgacttaata cactttgtga
     2041 acaaatatca tgcgaaagca ttttttgcgt cattttttgt tcttttcgaa tctctttaat
     2101 gatcgttcca aaggactcga ttaacgtttc cataagtatc ctccccaaaa tatgcgtatt
     2161 cgcattctat tcgtatttta ctttaggaag tcgcaaactt caagaaaaga cttgcaacta
     2221 aataatatac tttagttatt taagaaaact ccactagaaa gagagcctca gtgtgtttgt
     2281 ctgtggccct cctactgaaa aatttggttt ttaaaatcat ttttggcgat aggttgctag
     2341 gaattctctc attttcttag ctgtttgttt caaatcatcc attttaggaa gataaacgat
     2401 tcgaaaatga tctggctggt tccaattaaa tccaccacca tgtacaagta gaatatgatg
     2461 ttcatgtaaa aagtccaaaa cgaatttttc atcatccaaa atattgaatc gctttgtatc
     2521 aatttttggg aatatataaa aagcagcttt tggttttacg gctgaaagac caggaatatc
     2581 attgattgca ttatagatat attctctttg ttcatagatc cttccgcctg gcaggagcag
     2641 ctcatcgaca ctttgataac cgcctagcgc ggtttggata atttgctgag acaatacatt
     2701 ggaacacaaa cgcatggagg acaacatatt cagcccttct atatagcctt tgacgtgtga
     2761 cttatctcca cttaggacca tccagcctac tcgaaatcct gctacacgat gagatttgga
     2821 tagaccgttc agcgtaacaa cgaacaaatc aggcgctaat gtagcaatcg gaatatgttc
     2881 tagaccatcc atcactaagc gatcatagat ttcgtcggaa taaataatca ggttattttg
     2941 tcgagctact tcaacgattt cttctaataa ttcttttgga taaagtgccc cagtaggatt
     3001 attaggatta atgataacaa tagcttttgt ccgactcgtt atttttgatt tgatatcatc
     3061 aatatcagga taccattctg cctcttcatc gcaaatataa tgaacaggtg tgcctccagc
     3121 taatgcaata gaagccgtcc acaacggata gtccggcatt ggaaccagta cttcatctcc
     3181 attgtccagc aacccctgca tacacatcgt gatcaattcg ctcactccgt tgccggtgta
     3241 gatatcattg atcgtcacat tcggaaaatg tttcagttgg caatattgct caattgcttt
     3301 tctagcagaa aagatcccct tggaatctga gtagccttct gagtcacggg cattcatgat
     3361 caaatcacga atgacttcgt ttggtgcttc aaatccaaaa ggtgcgggat ttcccgtgtt
     3421 caattttaaa atactaatgc cctcttcttg catccgctcc gcttcttcta gaacgggacc
     3481 gcgaacatcg taactgacac cttctaattt gttggatttt tcaaattctc tcatcactta
     3541 gccaatccct catttcaaaa agttagaact ttccaaattt tttgttattt actatttcaa
     3601 tatcatactc catcctagaa aattttgcca cttatttagg aaaaacgtaa gtattaaaaa
     3661 aacacaaaca agcgttgaga acttaattgt catgatagtc attccataga ttcgctgccc
     3721 aatccattgc aattccacaa atgattccta gcataaaacc aagcaaaaaa cgtccgaatg
     3781 caagtccaat caatacacct aagatcattc ccagtcctga aaattctccg tcatatttct
     3841 ccatcttaat aagtcctccc atttttgagc ttgacaacta tgtaaaacct cgctatcatt
     3901 agtgtgttat tattacgcag atgtgttgga attggcagac aagcatgatt gagggtcatg
     3961 tgagcgttag ctcgtgtggg ttcgagtccc atcatctgca ctacaactcg tgaagttaat
     4021 tttgcttcac gagttttttt gtttgaacgt ttctttatgc cattatatac atatcactgt
     4081 atcctttaca aaaagaacgt acaatcatgt aaacagcctg aggtgagtat atgaaggtcg
     4141 gaaacaagct actcgtagaa acttgcaagt gttaaaacaa ttaatcgaaa aacgagtaaa
     4201 atccctcacc taatactaaa gcgagggatt ttttgtatat tatctgttta tcaccgttat
     4261 tataaaggta caaataccaa gcacggttaa tccaaattgc ataaattcat ttttttgtac
     4321 actcatgctt ttcattagct ctttaactgc cattagtact aagatggcga taacaacata
     4381 aagtatatag tacgtccgca ttccggaagc ccatactgtg ggagaaaatc ccataattaa
     4441 ccttgaacaa aatcccatta tcatcaaaat aactaaaaaa atagaagttt tcttattgtc
     4501 aaaacttaaa taaattccaa caattaaaca tagtaataat gccaagacta ctaaagtagc
     4561 tatccaagta cctggataaa aaagtgacag tttcgttcct aactctgtaa agagattatt
     4621 caggttacta ctactccaaa tcattgccct tttatttcca ttgacgtaag taaagctttg
     4681 acccattgta ttaccaaaat aaataatcag gtttaagaaa aacggtaatg cagtcaatat
     4741 acgcacataa ta
//
LOCUS       DACGEU010000135         4741 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.140, whole genome shotgun sequence.
ACCESSION   DACGEU010000135 DACGEU010000000
VERSION     DACGEU010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4741)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4741)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4741
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.140"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(25..1023)
                     /locus_tag="IXR40_002684"
     CDS             complement(25..1023)
                     /locus_tag="IXR40_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HAQ4362471.1"
                     /translation="MKKWLLLLIGMGILFTGCTSENTRTKATIETDTTIETKKSKTQS
                     TEQTTTEMKQSVETSASSITESSSEEVKNTLWDTNKASKLETFVTQWGKTLGQEYKSY
                     NLQNNVSLYGTPLPQAVINGDWKMAINEAPVTVQWSEDGTGHADFNLVAVYSDVETGE
                     YLGQHVYFFGFQNGQPKVYLTQQNQGNENNYLYFNETQNQQLKQGFSDIVNGQTPQTP
                     VVEESTQQATTTTTQSTSSSGISSWEAAKESVLNNKALWLYDSPDKNVSNTNLISTNE
                     YMKDLMQDENGSYYSINIVTDDDGNTTMAGGKQFRVYTDGRISQRIGMTNNFQMIK"
     gene            complement(1098..1394)
                     /locus_tag="IXR40_002685"
     CDS             complement(1098..1394)
                     /locus_tag="IXR40_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362472.1"
                     /translation="MAKLIVLGGLIYGGYWLYQYMLAHPNIDKGKVIKTVGVIIVGLI
                     ALTKKNNTNSPKIMRTYRCRGCGREISTSFNPSESPQGRDRCHTGYRHYWERID"
     gene            complement(1387..1680)
                     /locus_tag="IXR40_002686"
     CDS             complement(1387..1680)
                     /locus_tag="IXR40_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362473.1"
                     /translation="MEIDETCLSNSYKSMNDFFEEMELDSELLYQFYLAFRGQQISFP
                     MKMYDRELVRKRIENMIEQEKTVDIRQLTEVYGFSARWIQKVIKQKERRRVHG"
     gene            complement(1826..2377)
                     /locus_tag="IXR40_002687"
     CDS             complement(1826..2377)
                     /locus_tag="IXR40_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1643 domain-containing protein"
                     /protein_id="HAQ4362474.1"
                     /translation="MIEKELVTTQTEVWRDPHHTHRYVFKRQWAIKGKEAEDKLAVVI
                     TIRPTDTEPFTNDLSMLLIEKNIRQLGFTGFIAVNLFSYTKAKSPRVFLRGNDEQSLE
                     ILTTVFTEKKINTIIFACGSITATSQVAYEQAKTIYDQLSAKQKKMTKVLINAEGKLS
                     HPLSIHVRNEWQLADSQLLFQEK"
     gene            complement(2551..2850)
                     /locus_tag="IXR40_002688"
     CDS             complement(2551..2850)
                     /locus_tag="IXR40_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase"
                     /protein_id="HAQ4362475.1"
                     /translation="MLETAIEVLEKCAQLVTASEEWGYESVTMEKEEIEMGMLPEDVH
                     LPRLVMTHLYIYCAPEDGKDYVVYFITDITSQREFVRGLLVEGRLVWSQIGGTDE"
     gene            complement(2877..3143)
                     /locus_tag="IXR40_002689"
     CDS             complement(2877..3143)
                     /locus_tag="IXR40_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HAQ4362476.1"
                     /translation="MDSLPVELQALCWNLIDQNVQKQFPLDYLQIFEFSTEKGNQKLV
                     HRQEEPEERKEYLISPKLRLKSVSQKIWAIDSGEYQTMLLPEEY"
     gene            3430..4173
                     /locus_tag="IXR40_002690"
     CDS             3430..4173
                     /locus_tag="IXR40_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362477.1"
                     /translation="MVVSKLPRNEDYLTNYDGYVVTTEHFDLANPVTKVDDIPDYEMY
                     SQTIDSLNKRFGNRVLKGIKIGYIASEKDRIIDYLADKDYDLKLLSVHHNGQFDYLDD
                     EVKDMDPAIVIPQYFAQLSEALVVIEADVFAHFDYGFRVFGLSVAEFKQYEAQFLPIL
                     DQVIKNKLAFELNAKSAYLYDNLALYEYVIDLYLSRGGTLFSVGSDGHYLEHFRFHFD
                     DLFALLKANGVTELAIYQKGKRIMVPLPV"
     gene            complement(4210..4707)
                     /locus_tag="IXR40_002691"
     CDS             complement(4210..4707)
                     /locus_tag="IXR40_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4362478.1"
                     /translation="MNNQITLAYLDYDDLDALQVVSVVSFYESFIDGADPLDMQGYLQ
                     TQLTTEILAVELAQSTSKFIGIKDHQILIGYMKVNDEKDAIEIQRLYLLKDYQNKGLG
                     QRLLDEANRYAKTKQKRYLRLTVYEKNHAGIRFYERHGFKKIGIKHFPLGKQDRICPI
                     LEKEI"
BASE COUNT         1404 a          907 c          694 g         1736 t
ORIGIN      
        1 ttctttgata aataatattt tcaattattt aatcatttga aaattgttag tcattccaat
       61 acgttgagaa attcttccat ctgtataaac acgaaattgt tttccaccag ccatggtcgt
      121 gtttccatca tcatccgtta caatattaat tgaatagtag cttccatttt catcttgcat
      181 tagatctttc atatattcat ttgtgctaat taaattagta tttgatacat ttttatcagg
      241 agaatcatac aaccataaag ctttattatt tagcacagat tctttagcag cttcccaact
      301 tgaaattcct gaactacttg tagattgtgt cgttgtagtt gttgcttgtt gagtagattc
      361 ttctactact ggtgtttgag gagtttgtcc attcacaata tcactgaaac cttgttttaa
      421 ctgttgattt tgagtttcgt taaagtacag ataattattt tcattacctt gattttgttg
      481 cgttaaataa actttaggtt gtccattttg aaaaccgaaa aagtaaacat gctgccctaa
      541 atattctcca gtttctacat cagaataaac tgctactaaa ttgaaatctg catgaccagt
      601 tccatcttct gaccattgta cggtaactgg tgcttcattg attgccattt tccaatcgcc
      661 attaatcacg gcttgtggta aaggagtgcc atacagactt acattattct gaagattgta
      721 gcttttatat tcttgaccta atgtctttcc ccattgtgtg acaaaagttt ctaatttgga
      781 agctttattc gtatcccaca aagtattctt aacctcttca gaagaagatt cagtgattga
      841 acttgcactt gtttccacag attgcttcat ttctgttgta gtttgttcag ttgattgcgt
      901 tttacttttt ttagtctcaa ttgttgtatc agtttctata gtcgctttag tcctcgtatt
      961 ctcagatgta caaccagtga ataaaattcc cattcctatt agtaataaca gccatttttt
     1021 cattatattt ccccctttca atttctccct cacgtactta ttctatcaga caattaattg
     1081 atctaaatgg taatctttta atcgattctt tcccaataat gtcgatagcc cgtatggcag
     1141 cggtctcttc cttgaggact ctcagatgga ttaaaactag tagaaatttc ccttccacat
     1201 cctctacagc gataagttct cattattttt gggctattag tattattttt cttagttaga
     1261 gctatgagtc caactatgat taccccaact gtcttaatta cttttccttt atctatattc
     1321 ggatgcgcaa gcatatattg atataaccaa tatccaccgt aaattaaacc acctaataca
     1381 atcagcttag ccatgtactc gtctcctttc tttttgttta attacttttt gaatccatct
     1441 tgcagagaaa ccataaactt ctgtcaattg acggatatct acagtttttt cctgttctat
     1501 catgttttcg attctttttc taactaactc acgatcgtac attttcattg gaaaagaaat
     1561 ctgttgccct cgaaaagcaa gataaaattg atagagcaat tctgaatcca gttccatttc
     1621 ctcaaaaaag tcattcatac ttttataaga gttactcaaa caagtttcat caatctccat
     1681 ctacacaccc cctgttattt tttacataat gaaaatagca tattactggg tacattgata
     1741 attcatataa catgtatcat cacatgtatt tttaaagtca aaaagcatgt aaaactactt
     1801 ataagtaaca tgagaaaata aaatgttatt tttcttgaaa taataattga ctatctgcca
     1861 attgccattc attacgaaca tgaatactta gtgggtggga taacttacct tctgcattta
     1921 tcaatacttt ggtcatcttc ttttgtttcg cactcaattg atcgtaaata gtctttgctt
     1981 gttcataagc cacttgactc gtcgctgtaa tcgaaccaca agcaaaaata atggtattga
     2041 ttttcttttc tgtaaaaaca gtcgttaata tttccaaaga ttgttcatca tttcctcgaa
     2101 gaaatacccg aggacttttc gcttttgtgt acgaaaaaag attcacagca ataaaaccag
     2161 taaatcctaa ttgtcggata ttcttttcga ttaataacat actcaaatca ttcgtaaatg
     2221 gttctgtatc tgttggacga atagtaatga ctactgctaa tttatcttcc gcttcttttc
     2281 ctttgatcgc ccattgtcgt ttgaaaacat agcgatgggt atgatgagga tctcgccaaa
     2341 cttctgtttg tgtggtcact aattcttttt caatcatctc tttttctcct atgctatttt
     2401 ttgttcaagc acttcaatta ccattgccgt tataagtgtc aatactagtt gaaaatattt
     2461 catattcttt ctcctttttt cttcagaatt tgatgaatcg cggtaaggat atcttctaaa
     2521 catttcgcaa tcattctcaa ataatcgatc ttattcatcc gttcctccaa tctgactcca
     2581 aaccaatcgt ccttctacca gtaacccacg aacaaattct cgctggctgg taatatctgt
     2641 aatgaaataa actacatagt cttttccatc ttctggtgcg caataaatat aaagatgtgt
     2701 catcactaaa cgtggtagat gaacatcttc aggaagcata cccatttcaa tttcctcttt
     2761 ttccatcgta acggattcat agccccactc ttcagaagca gtgaccagct gtgcacactt
     2821 ttccagtact tcgatagccg tttctaacaa gtcctttcgt tcctttcttt tagatactag
     2881 tattcttctg gtaataacat cgtttgatac tcacccgaat caatggccca tattttttga
     2941 gacactgatt tcaaacgaag cttaggtgaa atcagatact cttttctttc ttccggttct
     3001 tcttgacgat gaaccaactt ttgatttcct ttttccgtag aaaattcaaa aatttgaaga
     3061 tagtctaaag gaaattgctt ttgaacgttt tgatcgatta gattccaaca taaagcttgt
     3121 aattccaccg gcaaactgtc cattactccc tttgtgacat aacgttatcc tttattttga
     3181 aacatttctt ttccctcctt tgccataaaa atagcccaat cttctattaa agaagattgg
     3241 gcttcatgga tataatatat atttgtaaat aaagttaatt cagttataat tatcaaaact
     3301 acacaattat taaagttttt catatctctt tgtttagtaa gtttttctaa atcttaaccc
     3361 gtggtgctag ttaatttttt cctagaggaa aatgtctaaa catgttggta aatcaacaaa
     3421 aaaacgcata tagtagtctc aaaactccca agaaatgagg actatttaac aaactacgat
     3481 ggttacgtcg tgacaactga acattttgac ttagccaatc ctgttactaa agtcgatgat
     3541 atccccgatt atgaaatgta cagtcaaaca atcgatagct taaataagcg ttttggcaat
     3601 cgtgttttaa aaggcatcaa aatcggttac atcgcttctg aaaaggatcg gatcatcgac
     3661 tatttagccg ataaagatta cgatttaaaa ttactcagtg tgcatcataa tgggcaattt
     3721 gattatttag atgacgaagt caaagatatg gatcctgcta ttgtgattcc tcagtatttt
     3781 gcacaacttt cagaagcact agttgttata gaagcagatg tctttgctca ttttgactat
     3841 ggttttcggg tatttggtct atccgttgct gaatttaaac aatatgaagc gcagttttta
     3901 ccgattctag atcaagtaat caaaaataaa ttggcattcg aattaaatgc taagagcgct
     3961 tacttgtatg acaatttagc gttatatgaa tatgtcatcg atttatatct ttcacgtggt
     4021 ggtaccttgt ttagtgttgg atcagatggg cattaccttg aacatttccg tttccatttc
     4081 gatgatcttt ttgctctgtt aaaagcaaat ggtgtgacgg aattagcgat ttatcaaaaa
     4141 ggaaagcgaa ttatggttcc attaccagtc taaaaaaacg tcctcagcat caaaagtgag
     4201 gacgtttttt tagatttctt tttctaaaat cggacaaata cgatcttgtt ttcctaaagg
     4261 aaaatgtttg atcccgattt ttttaaatcc atgacgttca taaaaacgaa tacctgcatg
     4321 atttttttca taaacagtca aacgtaaata acgtttttgt ttcgttttag cataacgatt
     4381 cgcttcatcg agtaaccgtt gccctaaccc tttgttttga taatctttga gcagatagag
     4441 ccgttgaatc tctatagcat ctttttcatc attgactttc atataaccaa tgagtatttg
     4501 atgatcctta ataccaataa atttactggt tgactgtgcc aattctactg ccaatatttc
     4561 agttgtcaat tgtgtctgta aatatccttg catatcaagt ggatctgcgc catcgataaa
     4621 cgattcataa aaactgacaa cacttacaac ttgtaaagca tctagatcat cataatctaa
     4681 atacgctagt gtgatttgat tgttcatcta actcctcctt ttgacatagt atactataaa
     4741 t
//
LOCUS       DACGEU010000136         4659 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.141, whole genome shotgun sequence.
ACCESSION   DACGEU010000136 DACGEU010000000
VERSION     DACGEU010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4659)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4659)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4659
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.141"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            15..746
                     /locus_tag="IXR40_002692"
     CDS             15..746
                     /locus_tag="IXR40_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004398644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HAQ4362479.1"
                     /translation="MVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGKSTFMK
                     SLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTYPSLRI
                     GQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWIFLDEP
                     FVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIASGPVQE
                     VFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            743..1582
                     /locus_tag="IXR40_002693"
     CDS             743..1582
                     /locus_tag="IXR40_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HAQ4362480.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            1583..2533
                     /locus_tag="IXR40_002694"
     CDS             1583..2533
                     /locus_tag="IXR40_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HAQ4362481.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            2674..3426
                     /locus_tag="IXR40_002695"
     CDS             2674..3426
                     /locus_tag="IXR40_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362482.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            3445..4596
                     /gene="queG"
                     /locus_tag="IXR40_002696"
     CDS             3445..4596
                     /gene="queG"
                     /locus_tag="IXR40_002696"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HAQ4362483.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
BASE COUNT         1573 a          778 c         1012 g         1296 t
ORIGIN      
        1 tggaacgtac ggccattgta attcaagacc tttcagccgc ttatcaaggg aaaactgttt
       61 tgaaaactat caacttgacg ataaatccac aaaaaattac cggtattatc ggaccaaacg
      121 gtgcaggaaa atcaacattt atgaaatctt tgctagagtt gataccagct actactggta
      181 aagtcacctt ttctggacag tcggtaaact cagtccgtaa aaaaatagcc tacgtggaac
      241 agcgaagtga attggatctt tcctttccaa ttgatgtatt aggcgttgta cttttaggaa
      301 catatccatc tttacgaatt ggacaaagac ctgggaaaaa agaaaaagaa cgtgcaagac
      361 aagctttgaa aaaagtaggg atggaagaat atgccaaaag acagatcagc gaactatcgg
      421 gtggacagct tcagagagtt tttattgcaa gagctctagc ccaaggagca gaatggatct
      481 ttttagatga accattcgta gggattgatg cgttaagtga acgaaagatc tttgacatct
      541 tgcaggaatt gaagaattca ggaaaaacga ttttgatcgt ccatcatgat cttcataaag
      601 tagaagaata tttcgatgag gttattcttt taaataaaca gctgatcgct tccggtccag
      661 tacaagaagt ctttacatcg aagaaccttc aattggccta tggtgagatc atcagacatt
      721 tagtaaaagg aggagagaaa aaatgatcca atcctttatt gatggattaa tgaattatca
      781 attcctgcaa tacgctttgg tcacttccat gcttgtagga cttgcttctg gagtcatcgg
      841 ttcttttatt attttacgag ggatgtcttt gatgggagac gctatctctc acgcagttct
      901 tccaggtgta gccatttctt atatgtttgg ttttagttac atctttggag ccactgcttt
      961 tgggatgcta acagcagcag tgattggttt cgtgactcag cggagccgat tgaaaaatga
     1021 tacagcgatt ggaattgtct ttagctcctt ttttgcatta gggattatct tgatttcata
     1081 tgcccagagt gcgacagatt tgtatcatat tttatttggg aatgtcttag ctgttaggga
     1141 aagcgatttg ttgctgacag cactcgttag tggaatcgtc ttgatatttg tctttttctt
     1201 ttataaagaa ttgaagatca catcattcga tccgacaatg gcaaaagctt atgggctgaa
     1261 cacatcgctg atccattatc ttttgatgtt ctttttgaca ttagtggctg tagtcagttt
     1321 acagacagta ggaacaatct tggtgattgc catgttgatc acaccagccg ccacggctta
     1381 cttgctaacg aaccatttac tgaaaatgat cattacagct gcaggaatcg gtatgctaag
     1441 tgcagttgtc ggtgtgtttt tcagttatag ttacaattgg ccatcaggag ctacgatcgt
     1501 gttagcatgt accgcatttt ttatccttgc ttttttattt tctccaacaa aaggaatttt
     1561 atttcagaaa ggaagcagat agatgaaaac aaaaaaatca ctctttttaa tcttggcagt
     1621 tagtttcttg gtattagccg gttgcggaaa gcaggcttct gaccaagcgg atgaaggaag
     1681 taaagaaaag ttgtcagtcg tggctaccaa ttcgatcttg gcggacatgg caaaagaggt
     1741 cggaacagat caaatagata tccacagtat cgtaccagtc ggaacagatc cgcatgaata
     1801 tgaagtacta ccagaagaca tcaaaaaggc aagcgatgca gatgttattt tatacaacgg
     1861 tttgaatctt gaaacaggta acagctggtt cgataacttg atggaaacgg ctaaaaaaga
     1921 agaaggaaaa gattattttg cagttagcaa aaatgtagaa cctctttatt taactagcgg
     1981 tgaagaacat acaaaagcag atccccatgc ttggctagac ctatctaacg gaataaaata
     2041 tgtggaggaa atcgcacgta tattctctga aaaagatgca gaaaatgcga cactctataa
     2101 aaaaaatgca gaagcatatg tggaaaaact aaaagaatta gatacacaag cgaaggaaag
     2161 ttttgcttct atcgaagaga acaaaaaatt attagtaaca agtgaagggg cattcaagta
     2221 tttttcacga gcatatgatt tgccagcagc ttatatatgg gagatcaata cagaaagtca
     2281 aggtacgcct gatcaaatga aagcgatcat tgatcagata agagcaaaag aagtaccggt
     2341 tttattcgtg gaaaccagtg tagactcaag aagcatggaa cgggtagcaa aagaaacggg
     2401 tttgaaaatc tatgataaac tgttcactga ttccatagca aaagaaggag aacaaggaga
     2461 ttcttactat cagatgatga aatggaatat tgaaacgatc catgaaggtt tgtcacaaac
     2521 aaaagaaagc tgaaaagtgc aaggtctagc ttgaggagca gaccttgcat tttttataag
     2581 agatatgaaa aaaaattatg ctgtttttcg tcgtacagat accttttttg aagaaattcc
     2641 gttatagtta gagtaaggaa ggaaggtgtg gctatgaatt ttacacgtaa agataaatat
     2701 acgattaaag aagaagtctt tcgattgatc agccagcagg aaaataccga caaggatcaa
     2761 gaccttcaat ttcttgaagc agaattagct aaattattca tagcaaatca aaatgagaca
     2821 acagaaccag atgaagagct gtacataggc aaatggttgt ttgatgaatt tcagccttta
     2881 gatgaaaata ccggtatcgg ttattttgtg ttcctttctc cagtcggctt cacacctggc
     2941 gtattagtta aacaaaacga cgaaataacc gtcaaagcat ggcctgcatt attttcagtc
     3001 atcaaagcag aaggagtaat caaaaagatc cagtcggcct attataaaag tcaatttatt
     3061 gccaacagca aattaatgaa tatgttttat aatcgtctag tagaaattgc taggcctggg
     3121 aaaatcccgc aaacattcac gtacacacag caaaaaaatc tctatgaaga agtattgtat
     3181 tcccgcgatc tgtctgagtt ttcgccatgg gaagaggtaa ggctccatga actgttaagt
     3241 acaaaaccag tttcattgaa tttttttaat gcattagata acaaaagaaa attaatttca
     3301 acaaattatt gggaagtatt tgctgcaaga aaaaaatgga tggaagaaaa gaagattgcc
     3361 gatcagcaga tccagtttgt ccagctgaaa aaagaaaaac tatattatgg gttatacagc
     3421 cgttaacagc aagcgaggaa gaccatgaca ttaaaagaag aaatcataca agaaagcaaa
     3481 cgattaggaa ttgacaaaat cgggttcacc acggcggaac cttttgattc attaaaagaa
     3541 tcgttggaag aacaaaaagc agctggccat acttctggct ttgaacatcc aaatatcgat
     3601 gagcgtcttt atccagaaat gacatttgat cagccgaaat cgatcatttc cattgcactt
     3661 gcgtatccta ctaggatcca tgaagaagtg cctagggatg aaaaacgcgg gcagtttgct
     3721 cgtgcttctt gggggatcga ttaccatgat atactcagag accgtttgaa ccgattgatc
     3781 gaattcatcc aaacaagagc agaaaaatgg caaaaagaag aggaatggcg tctagctccg
     3841 caagtagata ctggagaact gatcgatgtc gctgtagcac agcgagctgg tttaggattt
     3901 attggacgaa acggattgtt gatcactgaa gagttcggtt catttgtcta tcttggtgag
     3961 atcgttacta atattgtatt tgagcctgat aaaccaggag aatttggttg cggtgactgt
     4021 atgcgctgcg tgactgcttg tccgacaaaa gcattgcttg gtgacggaag aatgaatgcc
     4081 cagcgatgtt tgtcttatca aactcagaca aaagggatga tgccggaaga atatcgtaaa
     4141 aaaatgcgaa atgtcattta tggatgtgat atctgccagt tagtctgccc ttacaatcaa
     4201 ggaaaagatt ttcattttca tgaagagatg gaaccaaaag tagacgaaat atatccaaaa
     4261 ttaaagccaa tgctttcgat gtctaataaa gacttcaaac agcaatttgg gcatttagct
     4321 ggttcatggc gtgggaagaa acctttgcag agaaacgcat tgattgcttt agctaatcta
     4381 ggtgatcgaa cggcattgcc tgagatttca gaatgtttaa cagatgtccg ccctgtcatc
     4441 agaggaacag cagcttgggc tattggacgt ctaggaacaa aagaaccgga aaaatggctt
     4501 gatgtattag atgaaatatt agctaaagaa acagaagaag tcgttataaa cgaattggaa
     4561 catgcccaga aattattgcg gagaaagtta aaataaaaaa atagttaaca ttattcaaag
     4621 tttttgtcca gtaattgttg taacaattac tggtttttt
//
LOCUS       DACGEU010000137         4591 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.142, whole genome shotgun sequence.
ACCESSION   DACGEU010000137 DACGEU010000000
VERSION     DACGEU010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4591)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4591)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4591
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.142"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            187..2856
                     /locus_tag="IXR40_002697"
     CDS             187..2856
                     /locus_tag="IXR40_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HAQ4362484.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFVYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDRGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEVSFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEKPRNTHRRRRRK"
     gene            complement(2947..3567)
                     /locus_tag="IXR40_002698"
     CDS             complement(2947..3567)
                     /locus_tag="IXR40_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAQ4362485.1"
                     /translation="MFLINATDEILSVNKVFYTVPAEKMSRVSSDINTITSRIGLTKA
                     MHMVLKYNQEDPPVPKTYEAIDLIIVDEIDRLKLQHLEQLRDIYDRNDLAMVLIGMPG
                     IEKRLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKWADLGIDIKLEDFSDYEAITTI
                     IKITKGNFRLIHRLFAQIDRILRINQMDKITVEVVEAARDSLVIGI"
     gene            3681..4220
                     /locus_tag="IXR40_002699"
     CDS             3681..4220
                     /locus_tag="IXR40_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362486.1"
                     /translation="MKKLFSALFILLFGFIGIGTSGNIVKASTMVEQTSEMAKTFSQL
                     TPEEQSYFKSKGFSDKDTFYTQKIEPQDPKTRFSANVLRLTASTKKITNTQGRTEYII
                     TSPNSAMYRISTRLSLGSAKSYTQTVNLANSYGYGGGMYFTFTGKRQYYSVKLAMQVY
                     NTFGVGSVSCTAGGLTIGK"
     gene            4217..4555
                     /locus_tag="IXR40_002700"
     CDS             4217..4555
                     /locus_tag="IXR40_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenic metallochaperone ArsD family protein"
                     /protein_id="HAQ4362487.1"
                     /translation="MIISYYVLNRSDDEGLFVFQSLHEDTMLKEFYNRIKNKQIETNL
                     YFLSDSILPFISNPKILNLLQTKDLKSLPIIVIDEEIVKYGAYLSVEELEKLTNIGMS
                     IQEDNGVHGT"
BASE COUNT         1421 a          790 c          860 g         1520 t
ORIGIN      
        1 aatttttaag ggtgggactt ttgattccta cccttttttt gcgtttattt ttgttatacg
       61 aacaaattat gaagttattt attctaaatt ttattttttt gtgaaaatta gactcttttt
      121 aagcagagaa aaacaaggat atgataaact gaatacaact tcatagaaat ttggtggaaa
      181 ataaatatga aaaaaaattt aaagtcattc tttagagaaa acggacgcta cgcagcagct
      241 agtttcctga ttccgttttt gattttagca cttgtttatc taagtatcgg gatctatcct
      301 ggaagcagca gaagtatttt ggcaagtgat gccttttcac agttttctaa ttttcatgcc
      361 agcttccgaa atgttcttct tggaaagcaa agtatttttt atacatggaa tgcttctcta
      421 ggattgaatt atttatcttt aatttcttac tatctaggcg ggatcttcac gccactggtg
      481 ttcttttttc caaaccagat gatgccagat gcactgtatg ttctgacttt gcttaaggtc
      541 ggctgtgccg gattggcttt ttggtttctt gcacgtacgt tcaagattcc tcgctggggg
      601 catgttgcac ttagcgtcag ttacgcattg atctcattta tcactgcaca ttcggagatc
      661 atcatgtggc tggatgcatt tgtttatctt ccattagtga ttttggggat tcatcgtgtt
      721 atggatctta aacggccgaa acttttattt atcagttatt tactcttgtt tttatccagt
      781 ttttatatgg gttttatgat tggcgtattt tctttcttat attttatcgc ccgtctattg
      841 acaaactggt cagaatataa aaaaacgatt gttccttatg gtatcacttc tttactggca
      901 ggcggcgctt caatgatcat tgtattgcca gcagtgctgg atcttcggtc aaatggcgag
      961 gcactgagtc agatcactac gttgaaaaca gaagcgactt cttatctgga tctaatcatg
     1021 aaaaatatga ttggtgttta tgacacgaca aaatacggat cgattccgtt cgtttacgca
     1081 ggtctgctac cattagtcct ctgtctgttt tattttgcca gtcggaaagt accgttgaaa
     1141 aataaatttt tgtacggcag tcttttcgcc atacttatcg caagtttcta tcttgttcca
     1201 ttgaatttgt tctggcatgg tatgcatgca ccgaatatgt ttttattccg ttatgcctat
     1261 ctgttctctt tcttagtgct cctgcttgca ggaaaaggat gggaaaagat agaacaagac
     1321 gatcgtgggc tgttgttagg aatcattttg gtcgtagctg ctctctttgc ggtggcatgg
     1381 ggcatcaaac ctgaaggaag ctacacctat gtgacgatga cttcctttgt attgacagtg
     1441 gttttcttag ggatttatgc ttttgctgtg ggattttatc agcataaaaa actttcattc
     1501 aatcatctga gtatattgtt attattgatc atgtctgctg aagcactggt caatacgaac
     1561 agtatgatcc atggcattct tgatgattgg aattatgctt cccgcagttt atatactgat
     1621 ccttatcctg acttgaaagc tcttgtaaat gaaacaaaaa aagattccga ctcgttttac
     1681 cgcttggaaa atctggatcc agtatctgca aacgattcga tcaactatgg ttacagtggt
     1741 atcagtttgt tttcttctat aagaaatcgt aattcttcct cttacctgga taaattaggt
     1801 ttccgttcaa gagggacaaa tttgaatatc cgttataaca ataatacttt gctaatggat
     1861 gggtttacag gaatcaaata taacatttct aaaaacgaaa gcacgttcag taaatatggc
     1921 ttccgccaag ctggtcaaag tggcgactat acactgtatc agaatgtcaa tgcattgcca
     1981 ctagcattta ctgcaccgtt gtccgttaat gatgttgagc agccagtgac agataatttg
     2041 accagtcaga caaacttgat caatacattg tctggtttaa atgaacagta ttttacattc
     2101 tatacaccta ctttgaagaa tcagttgaat acgacgatca caaagacaac gactggcgtc
     2161 acttactcag aaacagcaga taaccagcca aaagagctca cttgggaagt ccatgtgcct
     2221 gcaaatacac aagcttactt aagtttgttc ccaaccaatt ttgcacaatt agaaagttct
     2281 agtgcgacga tcactgtcaa tggtacatcg cgaaaaacgc aaatcaacat ttctggtcaa
     2341 tactatgatc ttggctatta tcctcaagag acaacagtga catttactgc aagtttttat
     2401 ggaacgaaag aagtaagttt catggagcct aaagtcgttg gtctagatgt tgtagcctat
     2461 caagccgcaa tgaatcagat caaagaaaaa ggtgtcgaaa tggaagccac tggcagaaaa
     2521 gcttctggga ctgtaaatac cgctgaagat tccatgttgg tgacaactat tccttatgac
     2581 aaaggatgga aagctaaaat tgatgggaaa ccagtcaagg tcagcaattt caaagacgca
     2641 ttcttgatga taaaagttcc agcaggtaaa catactgtca ctttcagtta cttgcctgaa
     2701 ggatttacga taggtgcaat cctttttgtc ctatgtattg cattgtttat tctttatgtc
     2761 tggtaccttg accgcaatcg ccccttttat ggcacgattg atccagcaat agaagaaaaa
     2821 ccgcgaaata cacacagaag aagacgaaga aaataaagaa acgatggaat ctgtgtcact
     2881 cttctattta aatggcaaaa atttcaatct ttaaatgaca aaaaccacct gatttttggt
     2941 ggttttttat atacctatga ctaaactatc tcttgctgct tcgacaactt ctacagtgat
     3001 cttatccatt tgattgattc ttaaaatccg atcaatctgc gcaaataaac gatgaataag
     3061 cctaaaattt ccttttgtga tcttaatgat agttgtgata gcctcataat cagaaaaatc
     3121 ttctagcttg atatcaattc ctaaatctgc ccatttgtat tccaaaatat gatgtgtttc
     3181 gtccttacta aggttatcaa attcatgtgc aaatcctatg cgagagtaaa gctgcggata
     3241 acgagacaat cttttttcaa taccaggcat accgataaga accattgcca gatcatttct
     3301 atcgtaaata tctcttagct gttctaaatg ctgaagcttt aaacgatcaa tttcatcgac
     3361 aataattaag tcaattgctt cataggtttt aggcacagga ggatcttctt gattgtattt
     3421 tagtaccata tgcattgctt tagtcagacc tattctacta gttattgtgt taatatccga
     3481 actgacacga gacatctttt cagctggtac agtataaaaa actttattta cacttaatat
     3541 ttcatctgtt gcatttatca agaacaagaa aaagtctgaa tattcaaaaa aaataacggt
     3601 gtacattttt aaaaggagat gtataatcga gatttagaaa gcgttttcct caaaatttaa
     3661 tgaattagga agtgattact atgaaaaaat tatttagcgc actttttatt ctgttatttg
     3721 gctttattgg tattgggact tctggaaata tagttaaagc tagcacgatg gttgaacaaa
     3781 caagtgaaat ggcaaaaact tttagtcaat taacaccaga agaacaaagt tacttcaaat
     3841 ccaaaggatt tagtgataaa gatacttttt acactcaaaa gatagagcct caagatccga
     3901 aaacacgttt ttctgcaaat gtattgcggt taaccgcatc tactaaaaaa attactaata
     3961 cgcaggggcg gacagaatat attataacaa gtcccaattc ggcgatgtat cgtatttcta
     4021 cacgcttgag tttaggtagt gcaaaatcat atactcaaac agtaaatcta gctaattctt
     4081 atggttatgg tggaggaatg tattttacat ttactgggaa aagacaatat tacagtgtaa
     4141 aattagctat gcaagtttat aatacatttg gtgtagggtc agtctcttgc actgcgggag
     4201 gattgacaat aggaaaatga taatttctta ctatgtctta aatagaagtg atgatgaagg
     4261 actcttcgtt tttcaatcat tacatgagga tacgatgcta aaagagtttt ataatcggat
     4321 taagaataaa cagatagaaa caaatttata ttttttaagt gactctatct tgccttttat
     4381 tagcaaccct aaaattctta acttgttgca gacaaaagat ttgaaaagtt taccgattat
     4441 tgtcattgat gaggaaattg taaaatatgg cgcttatcta agcgtagaag aattagaaaa
     4501 attaactaac attggaatga gtattcagga ggataatggg gtacatggaa catagaatga
     4561 atatgcacag ttgagaacgg aatttgacat t
//
LOCUS       DACGEU010000138         4521 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.143, whole genome shotgun sequence.
ACCESSION   DACGEU010000138 DACGEU010000000
VERSION     DACGEU010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4521)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4521)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4521
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.143"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..974)
                     /gene="lacD"
                     /locus_tag="IXR40_002701"
     CDS             complement(<1..974)
                     /gene="lacD"
                     /locus_tag="IXR40_002701"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HAQ4362488.1"
                     /translation="MKKMSIEKQERLKRLTDEAGIISALAIDQRGALKKMINQYKEAT
                     SEDIIQFKQMVSQYLTPYASAILLDPEYGLPAAALREKECGLLLAYEKTGYDAKMPGR
                     LPDLLNSWSVKRLKEVGADACKFLLYYDVDEPVEINVQKQIVIERIGSECEAEGIPFF
                     LELLSYDATIGDPSSLDYAKVKPHKVIEAMREFSKERYQVDVLKVEVPVNMRFVEGYG
                     QDTCYSQAEASAYFYEQSKVTEQPFIFLSAGVSAALFQDTLRFAKQSGSTFNGVLCGR
                     ATWAKGVAPFVTEGEEKASSWMLEEGKQNIKELSTLLEETATSIYVNK"
     gene            complement(971..1429)
                     /locus_tag="IXR40_002702"
     CDS             complement(971..1429)
                     /locus_tag="IXR40_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIA"
                     /protein_id="HAQ4362489.1"
                     /translation="MTIIHEENIFLQQPLDNQEEAFKFLAKQTFCLGIAHDEKEVYQK
                     LLEREKEGTTGIMSGFAIPHAKSQTINEPSLIIVTLKKGIEWNSLDRQSVDFIFALFI
                     PDSEAGTTHLKLLSLVARSLMRKEVTEQLRAAKSKIEIATILTKEIGEDI"
     gene            complement(1426..2889)
                     /locus_tag="IXR40_002703"
     CDS             complement(1426..2889)
                     /locus_tag="IXR40_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4362490.1"
                     /translation="MGKYQLIAATGCPTGIAHTYMAQEALEQAARKKGITIKVETHGQ
                     IGIENELTAEEIKQADAVIIAADKDVHSERFVGKRVIDVSVSTGIKDAQRLIDEALAG
                     KGTVLADNEAADTLEPEAISGANFGRSIYKNLMNGVSHMLPFVVAGGVLIAISFAVWG
                     IYSSDPDHAQYNATAAMVKAVDDAAMGMMVPVLAAYIAEGIAKRPGLVVGFVGGIVAM
                     NGGTGFLGGILAGFLAGYFILFLQKLLIILPKQLDGLKAIVLYPVIGVAFIGIVMSLL
                     AGPMKAINEGMMSFLAGFEYSNPLVLGVIVGCMCAFDMGGPVNKAAYVTGTALLTQGN
                     TTFMAGASAACIAPPLITGFATLLFGKYFDTNDRNAGLVNFILGSTHITEGAIPFAAK
                     DPIRVLPTMMLGSSIAAVLTYLFGVQVPAPHGGFLVLPVVTGKIQWVTAILIGSIVGG
                     VILGLIQKKRVTDKDKKRDNKATNRTVIEEGRAGGLS"
     gene            complement(2871..3803)
                     /gene="pfkB"
                     /locus_tag="IXR40_002704"
     CDS             complement(2871..3803)
                     /gene="pfkB"
                     /locus_tag="IXR40_002704"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010779385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HAQ4362491.1"
                     /translation="MSIYTCTMNLAIDLFIETDEMHPFMVNRTKEDDIQANGKGVNVS
                     LVLKMLDFPSTALGFSAGFTGKYIEDYLQQKQIQTEFIEVPGMTRINVFTQVNQTGEE
                     YKLVNQGPEIPQTAVHNFLNQIRALQAGDYLCVSGSLPRGLSPKVLIEISRICLIIDS
                     SDQEVMDCLPYRPFLLKPNEEELSSWFGRKMVTDEDYFVYGQRLVESGAENVLLSLGE
                     KGAILFTKDRVIRGNSPKGKVVNTACAGDAMLGTFLAGYMNRRSLDETLRKSIAAGSS
                     TAFRKGLTDFLDVEELSKQIKIKEERFERWENIN"
     gene            3945..>4521
                     /locus_tag="IXR40_002705"
     CDS             3945..>4521
                     /locus_tag="IXR40_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAQ4362492.1"
                     /translation="MNHKLSETEQYLWNFIEHLILEIPNYSIVKLSEQANVSTATIVR
                     TMKKKGYEGFTSFKHHLKEGENKNINFSFLDKVDKGIRRAILKNEQEVVRTINMLEIG
                     NIEDAIQRIKFADRVFVFARGFSEMIGQEMLVKLQLTGKNCQMHTDPEIIKSISRKLT
                     KKDSVIFVSLNGEKTNKNIKNKIYVFIFQFFK"
BASE COUNT         1354 a         1016 c          724 g         1427 t
ORIGIN      
        1 tacttgttaa cataaataga agttgctgtt tcttctaata gtgtacttaa ttctttaata
       61 ttttgttttc cttcttctaa catccaacta ctcgcttttt cttcgccttc ggtaacaaaa
      121 ggtgctactc ccttcgccca tgttgctcgc ccacataaga caccattgaa tgtcgaacct
      181 gattgttttg caaaacgcaa tgtatcttga aatagtgcag cgctgactcc cgcacttaaa
      241 aaaataaacg gttgttcagt cactttcgat tgttcataga aatacgcgga tgcctctgct
      301 tgactataac aagtatcttg cccatatcct tccacaaatc tcatattcac tggtacttct
      361 actttcaata catccacttg ataacgttct tttgaaaatt ctcgcatggc ttcaatcact
      421 ttatgcggtt ttacttttgc atagtcaaga gaagacggat cgccaatagt tgcatcgtaa
      481 gaaaggagct ctaaaaagaa aggtatgcct tctgcttcgc attctgaacc aatccgttct
      541 ataactattt gtttttgcac attaatctct actggttcat caacgtcata gtacaataaa
      601 aatttacaag catccgcacc cacttctttt aaccttttca ctgaccaact attcagtaaa
      661 tctggtagtc ggcctggcat tttcgcatca tagccggttt tttcataagc tagcaacaaa
      721 ccacattctt tctctcgaag cgctgctgca ggcagaccat attctggatc gagtaaaata
      781 gcggaagcat acggagtcag gtactgagaa accatctgtt taaattggat gatatcttct
      841 gatgtagctt ctttatattg gttgatcatt ttcttcaaag caccacgttg gtcgatagct
      901 agcgcgctaa taattccagc ttcatccgtc aatcgcttca aacgttcctg tttttctata
      961 ctcattttct tcatatatct tcacctattt ctttagttaa tattgtagct atttctattt
     1021 ttgattttgc agctctcaac tgttctgtaa cctcttttcg catcaatgat cgtgcaacga
     1081 gagacaataa tttcaaatga gtcgttcctg cttctgaatc tgggataaat aacgcaaaaa
     1141 taaaatcaac tgactgtcta tctaaactgt tccattcaat tccttttttc agtgtgacga
     1201 taatcaaact aggttcattg attgtttgag acttcgcatg agggatagca aaacctgaca
     1261 ttattcctgt agtaccttct ttttctcttt ccagaagttt ttgatatact tctttttcgt
     1321 catgagcgat tcctaaacag aatgtttgct ttgctaaaaa cttaaatgct tcttcttgat
     1381 tatctaatgg ctgttgtaaa aaaatgttct cttcatgaat gattgtcatg ataaacctcc
     1441 tgctcttcct tcttcgataa ctgtacgatt tgttgcttta ttatccctct tcttgtcttt
     1501 atcagttact cttttctttt ggatcaaacc tagtatcact ccaccaacga tcgaaccaat
     1561 aagaatcgct gtaacccatt ggatttttcc cgtcactaca ggtaacacta aaaaaccgcc
     1621 atgtggggct ggtacttgga caccaaacag ataggtcaag acagcagcaa ttgatgagcc
     1681 taacatcatc gttggtaata ctcggatcgg gtctttcgca gcaaacggaa tagctccttc
     1741 cgtaatatga gttgatccta aaataaaatt aaccaaacct gcattacgat cattagtatc
     1801 aaaatattta ccaaacaata aagtagcaaa accagtaatc aacggtggtg caatgcaagc
     1861 tgctgacgca ccagccataa aagtcgtgtt tccttgtgtc aaaagagctg ttcctgttac
     1921 atatgccgcc ttattaaccg gtcctcccat atcaaacgca cacatacagc caacaatcac
     1981 gccaagaaca agtggattcg aatattcaaa tccagctaaa aagctcatca ttccttcatt
     2041 tatagccttc attggacctg ccagcaaaga catcacgatg ccaataaatg ctacaccaat
     2101 aactggatat aagacgattg ccttcaagcc atctagttgt ttaggtaaaa ttatcagtag
     2161 cttttgcaaa aataagataa aataacctgc taagaaccca gctaaaatac ctcctaaaaa
     2221 tccagtaccg ccattcatgg ctacgattcc accaacaaat ccaacgacta accctggacg
     2281 tttcgcgatc ccttctgcaa tataagctgc taaaactgga accatcattc ccattgctgc
     2341 atcgtcaact gcttttacca ttgccgctgt agcattgtat tgtgcatgat ctggatcaga
     2401 agaatagatt ccccaaacgg caaatgaaat agcaatcaat actccgccag ctaccacgaa
     2461 aggcaacata tgagagacac cgttcatcaa atttttatag atgctacgac caaaattagc
     2521 accacttatc gcttctggtt ctaaagtatc agcagcttca ttatctgcta agacagtacc
     2581 ttttcctgcc aatgcttcgt caatcagccg ttgtgcatcc ttgattcctg tactgacaga
     2641 aacatcaatg actcgttttc ccacaaatct ttctgaatgg acatctttgt ctgcggcaat
     2701 aatgacagca tctgcctgtt tgatttcttc agccgttaat tcattctcga tcccaatttg
     2761 tccatgggtc tccactttga tcgtgatgcc ttttttccta gctgcttgct ctaatgcctc
     2821 ttgcgccatg taggtgtgcg caattcctgt cggacaaccg gttgctgcaa ttagttgata
     2881 ttttcccatc tttcgaacct ctcttccttg attttgattt gtttacttaa ttcctccaca
     2941 tccaaaaaat cagtcagtcc tttacgaaaa gcagtagagc tgcctgctgc tatgctttta
     3001 cgtaacgttt catcaagcga tcgtcgattc atgtatcctg ctaaaaaagt gcctaacatg
     3061 gcatcacctg cacatgctgt attgacaact tttccttttg gcgagtttcc tcgaatcacc
     3121 ctgtctttcg taaaaagaat cgctcctttc tcaccgaggg ataacaaaac attttctgcg
     3181 cctgactcta ctagtcgttg tccataaaca aagtaatctt catctgtaac catttttcgt
     3241 ccgaaccaag aagaaagttc ttcctcattt ggtttcagca aaaacggtcg atagggtaaa
     3301 caatccatga cttcttgatc actactatca ataatcaaac aaatccgact gatttctatt
     3361 aaaacctttg gagacagccc tcttggtaaa ctcccagaaa cacaaagata atcccctgct
     3421 tgtaatgctc ttatttgatt taaaaaatta tgaacagctg tctgcggtat ttcaggtcct
     3481 tgattcacta atttgtattc ttctcccgtt tgattgactt gtgtaaatac attgatacgc
     3541 gtcataccag gcacttcaat aaactctgtt tggatttgtt tctgctgtaa atagtcttct
     3601 atatactttc ctgtgaaccc agcagaaaaa cctaatgccg tacttgggaa atctagcatc
     3661 tttaatacta gtgacacatt cacccctttt ccgtttgcct gaatgtcatc ctcttttgtg
     3721 cggtttacca taaaaggatg catctcatct gtttcaataa atagatcaat tgccaaattc
     3781 atcgtgcatg tgtagataga cataaccaac gacctccttg attctattat gaaatacgcg
     3841 aaatagaaaa tgttttctta atcgtcccaa cacaaagaaa acctttacat ttataaactc
     3901 gtcgtgcttt ttttaactaa cttttggtga aagaaggaaa gaatatgaat cacaaattaa
     3961 gtgaaacaga gcagtacctc tggaacttta tcgaacacct catcctagag atccctaact
     4021 attccatcgt gaaactaagt gaacaagcaa atgtctcaac agccaccatt gtgcggacaa
     4081 tgaaaaagaa aggctatgaa gggtttactt cgtttaagca tcatctaaaa gaaggagaaa
     4141 acaagaacat caatttttca tttttagata aagtagacaa aggaatccgc cgagccattc
     4201 taaaaaatga acaagaagtg gtacgtacaa tcaatatgtt ggaaatcggg aacattgaag
     4261 atgcaataca aagaatcaaa tttgctgacc gggtttttgt ctttgcccga ggattttcag
     4321 aaatgattgg ccaagaaatg ctggtaaaac ttcaattaac gggaaaaaat tgtcagatgc
     4381 atactgatcc agaaattatc aaaagcatca gtcggaaact aactaagaaa gacagcgtta
     4441 tttttgtttc tttgaacggt gagaaaacaa ataaaaacat caaaaataag atttatgtct
     4501 ttatttttca attttttaaa t
//
LOCUS       DACGEU010000139         4453 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.144, whole genome shotgun sequence.
ACCESSION   DACGEU010000139 DACGEU010000000
VERSION     DACGEU010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4453)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4453)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4453
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.144"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            244..453
                     /locus_tag="IXR40_002706"
                     /pseudo
     CDS             244..453
                     /locus_tag="IXR40_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313007.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(656..1975)
                     /locus_tag="IXR40_002707"
     CDS             complement(656..1975)
                     /locus_tag="IXR40_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element IS1678 family transposase"
                     /protein_id="HAQ4362493.1"
                     /translation="MTSLHKNQVKFNSNITISHTGGQLSSDSGLVLVKELMNIFGFSE
                     LAKQHIHIEDERAYFTHDNLSILEQFIMQLIAGYSADSAANLLRQDPVFKAVLDRKEL
                     ASQSSLSRFLDRLSEENIHELQALNQELIDKARLIRNDTELIIDLDSTHSDTFGHQEQ
                     TNYNTHYQTYGYHPLVAFDGLTGDFLKAELRSGNQYTSKGVKEFLTPLLEHYNHSLPN
                     TDILVRGDSGFATPGVYDSCESKKSHYVIRLKNNRRLGQIAEKSVLYGDNQKWEEREV
                     QYFSTTYQAQSWSQSRRVCIRSTREAGELLFRHEFIVTNLSENVSPDTIFSIYAKRGT
                     MENFIKEAKAGFYFDKTDSPRFLENHVRMMLSLIAYNLVNFLRTIGFEEVQKGMTIHS
                     IRLKFLKVAGKLVQTGRRVYLKLSSYHVYQNEFYRVFARLRRASQWI"
     gene            2099..2269
                     /locus_tag="IXR40_002708"
     CDS             2099..2269
                     /locus_tag="IXR40_002708"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362494.1"
                     /translation="MVLIKSMNYSGGSGISSVRLKEKEYTQKIIHIPKPEIKRFEIKD
                     YSALGLFSIGYW"
     gene            complement(2432..3772)
                     /locus_tag="IXR40_002709"
     CDS             complement(2432..3772)
                     /locus_tag="IXR40_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAQ4362495.1"
                     /translation="MSYSEFTKELLDILDLNLTFHEDAFRKERINDETCFVFDGTLTY
                     QPEECFHCHYQNKQTIIKWGWKKVSILLNDVSNYKTIVRINKQRFKCKHCGKTFLAED
                     SVSDRRCSIARRVKQAILELLSEPISMSLIARMKHISPTTVIRILRSLRPKTVSLNQP
                     LPEVVCFDEFKSVKNVSGAMSFVMMDGKTHQLIDIVENRQLNPLRDYFLRYPRKVREQ
                     VRLVVSDFYTPYRTLVKECFPNARIVADRFHISQHIGRAFTNHRIQVMKTFKKGDRRS
                     KHLKKYWRLLQKNAWELNGQHRYWRPSFRDHLTEAEIVDRLLYYDDSLKRGYEVYQVF
                     LSAIRRQDVPEFVALLKEDYKELPEHYQPVFTTFKKYRTEIKRALRVPYSNGPIECLN
                     NHIKVLKRIAYGFRNFQNYRERIFLYRGKYFKKTKNTTQLTKARTTTRLDKIAV"
BASE COUNT         1374 a          736 c          875 g         1468 t
ORIGIN      
        1 gaattttgtt taaaaattaa atgtaactgg aaaagaatgt atttctatat tgatggtgat
       61 gatgctctta cattcggtaa aactactttt tctagtttta attttcagtt tctattaaaa
      121 aataattttt atggtttatt gaaataaggt tgcgaaggaa gatgtagagt tatttgcact
      181 gttgtgttgg tatatctctt aatgctgtgt ctttttgggg agattaatta gtggagtgat
      241 tatatgagta tagatgattg tttagaagaa caaataagat tatttttaaa gtttttaaaa
      301 gttaaagttc aaaataacta cttcacatgt tatagttatg cacaccctgt tttaaatagt
      361 cttcctttta attctttagt gcaaggattg attacaaata ttgttttatt agtctgtaca
      421 ccaaatgaaa tatttgtaaa aaagataggc agcctgaata attcatagct ttaattcttt
      481 ggcacatttt attgaaatat gtatcactaa tatccctatc aactgatttt gactaaaaag
      541 ttacttcaaa cattcactgt tcaaaaatat tgaggaataa attttgggtg taaggcattt
      601 tgagcatact tctccctgga taacttccca gtaaaaaaat cgttagattg ttggattaga
      661 tccattgact ggctcgcctc aggcgagcaa agaccctgta gaattcattc tgatacacat
      721 gataactaga taatttgaga tagactcgtc tacccgtttg gactaatttc ccagcaactt
      781 tcagaaactt caatcgaata gaatgaatgg tcattccctt ttggacttct tcaaagccaa
      841 tcgttcttaa gaagttgact aagttgtaag ctatcaagct gagcatcatt cggacatgat
      901 tctccaaaaa gcgaggactg tctgttttgt caaagtaaaa gccagctttc gcttctttaa
      961 tgaagttctc cattgtgcca cgtttggcat agatagaaaa gatggtatca ggagaaacat
     1021 tttctgatag attcgtcacg ataaattcat gtcgaaagag tagttcgccc gcttcacgtg
     1081 ttgagcgtat acacacgcga cgactttgtg accaggattg tgcttgataa gtggtcgaga
     1141 agtactgaac ttctcgttct tcccactttt gattatcgcc ataaagtact gatttctcag
     1201 ctatttgacc tagtctacga ttattcttca gtcgaataac ataatgactc ttttttgatt
     1261 cacacgaatc atacacacca ggtgtagcga acccgctgtc tccacgaacc aagatgtcag
     1321 tgtttggtag agagtgatta tagtgctcta ataaaggtgt gagaaactcc tttacgcctt
     1381 ttgatgtata ttgatttcct gaacgtagtt cagcttttaa gaagtcacca gtcaatccgt
     1441 caaaagctac caatggatgg taaccatagg tttggtagtg tgtattataa ttcgtttgtt
     1501 cttggtgacc aaatgtatct gaatgggtcg aatctaaatc aatgattaat tccgtatcat
     1561 tacggatgag gcgtgcttta tcgataagtt cttggttcaa agcttgaagt tcatggatat
     1621 tctcctcaga tagtcgatct aaaaatcggg aaagtgaaga ttgagaagcg agttctttcc
     1681 tatctaaaac agctttaaac acaggatctt gtctcaggag attagctgca gaatcagctg
     1741 agtaaccagc aattaattgc ataatgaact gctcaagtat ggataagttg tcatgagtaa
     1801 aatacgctcg ttcgtcttca atgtgaatgt gttgcttagc cagttcagaa aaaccaaaga
     1861 tgttcatcag ctctttcact aggacgagac ccgaatcact cgataattga ccacctgtat
     1921 gagaaatagt gatatttgaa ttgaatttta cttggttttt gtgtaagcta gtcatgaaaa
     1981 gaactccttt cttttggttg gtttagtcac tttaaccata gcagaaaggg gttctttttt
     2041 catcacttaa cgggtgaaga tgaaaaagta attgtaagct gccgtgaggc agtttcacat
     2101 ggttttaatt aaaagtatga attattcagg aggcagtggt atttcttcag taagattaaa
     2161 agagaaagaa tatactcaaa agattattca tattcctaag cctgaaatta agcgttttga
     2221 gataaaagac tattctgctt tagggctgtt ctcaattggt tactggtgat aaaaaataag
     2281 aatactaaaa ctatacgtag aatataagta atcggcatca atcctaatta tgtgattgaa
     2341 tgccgatttt tgttacgcgc tatttttaat ggctcttcgt caatgagtgt tggtgaagaa
     2401 attcaataga ataatcgaga tactcacacg gctagacagc tatcttgtct agccgtgttg
     2461 ttgttctggc tttagtcagt tgggtagtgt tcttagtttt cttgaaatat tttcctcgat
     2521 ataaaaagat tcgttctcgg tagttttgaa agtttctaaa gccataggca attcgtttta
     2581 gtactttgat atggttgttc aaacattcta tagggccgtt ggaataggga actcgcaacg
     2641 ctcgtttgat ttctgttcga tatttcttga aggtcgtgaa cactggttga tagtgctctg
     2701 gcaactcctt gtagtcttct tttaggagcg cgacgaattc aggaacatct tgtcttctga
     2761 tagcggaaag aaaaacctgg tagacttcgt agcctcgctt taaggagtca tcataatata
     2821 atagccgatc gactatctcc gcttctgtca gatgatctcg aaatgacgga cgccagtagc
     2881 gatgctgacc attcaattcc cacgcattct tttgaagtag tctccagtat ttctttaagt
     2941 gcttcgaccg acgatcccct tttttaaagg tcttcattac ttgaattcgg tggttggtaa
     3001 aggcccgacc gatgtgttgg ctaatatgaa agcgatcggc gacgattcgg gcattcggaa
     3061 aacactcttt caccaatgtg cgatagggtg tatagaaatc tgaaaccact agacgtactt
     3121 gttcacggac ttttctaggg tagcgcaaga aatagtcgcg taaaggattg agttgccgat
     3181 tttccacaat atcaatcagt tgatgggtct tgccgtccat catgacaaag ctcatggctc
     3241 ccgagacgtt tttcaccgat ttgaattcat cgaaacacac cacttctggt aacggctggt
     3301 tcaaagaaac ggttttaggc cgaaggctgc gaagtattcg aatgacagtg gtcggagaaa
     3361 tgtgcttcat acgtgcaatc aaagacatag aaataggctc acttaatagc tcaagaatgg
     3421 cttgtttgac tctgcgggca atggagcagc gacgatcgct aactgaatct tctgctaaaa
     3481 aagtctttcc acagtgttta catttgaagc gctgtttgtt aatccgcaca atggtcttgt
     3541 agttactgac atcattcaat aagatggata cttttttcca gccccattta atgatcgttt
     3601 gcttattttg atagtggcaa tggaagcatt cctctggttg ataggtcaat gtgccatcaa
     3661 aaacaaaaca tgtttcgtca ttaatgcgct ctttgcgaaa ggcatcttca tgaaaggtaa
     3721 gatttaggtc tagaatatct agtaactctt tggtaaactc tgaataggac atcttgaaac
     3781 actcctttga atggttttcg tcgactttat tctaaaggat ttcaaggtgt ctgtttgcgt
     3841 ttattagaaa aaagaaaaag tattggcaac agaaggcgtc accaacacta gatattatag
     3901 atccttttta attatctgta agaagaataa ttttatttta ctcatattcg ttttcacttt
     3961 gaagaagtaa attgcaattt cttataagtt aagcagctat gcaaaaggct atttattcta
     4021 ttgtgaaata taagatgtag ttgaaacagg atatatagaa tcaaaatacg aatcttattt
     4081 tgatttttct agttttttga aaaaagcacc ctttgatcgt tgtattagtg gaaaagagaa
     4141 aaaggagcat acttatcatg tcacaaaact acaactaaat atctaaacaa caccaatttg
     4201 atgcctattg aaaaaaagta ttgcgaaatg aagccaagtc tattagaaaa tgaaataata
     4261 gaataaaaga aaatgggaaa ccgctgaatg atgtaaatga aggtaagtat ccacgaacta
     4321 attttgatga acaagatatc tattttttat ttgtattgga gatactagtt taatatcaaa
     4381 agttatcagc agtcataatt agttatccaa tgtaaaaagt acaaacaata gttgttatgc
     4441 agaatagttt atg
//
LOCUS       DACGEU010000140         4433 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.145, whole genome shotgun sequence.
ACCESSION   DACGEU010000140 DACGEU010000000
VERSION     DACGEU010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4433)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4433)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4433
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.145"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(543..2048)
                     /locus_tag="IXR40_002710"
     CDS             complement(543..2048)
                     /locus_tag="IXR40_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAQ4362496.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            complement(2045..2731)
                     /locus_tag="IXR40_002711"
     CDS             complement(2045..2731)
                     /locus_tag="IXR40_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4362497.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="IXR40_002712"
     CDS             complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="IXR40_002712"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HAQ4362498.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFDQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
BASE COUNT         1239 a          919 c          728 g         1547 t
ORIGIN      
        1 tctttttgtt ttaacaactc tttaatctta tcagattcag aagagaatgt caacaacttc
       61 tttgtttatt ttttctaaac gtctttgcca ctcattagca gcgacttgat tatcatacca
      121 tctttattgt tatttgtcaa taactttttc gaagtttttt tcgataaaat caagctttat
      181 tagctatctc atccaaacga cttcgttatt ataacatgac atcaaaagtg cgtcaacact
      241 attttttata atttttagtg acaccttaaa ggaatcattt agaacaaata ataatatagc
      301 aatctcttta taaaattgca atagaaaatt ccctattttt atttattatt tttaaacacg
      361 aatattacag cattttattg ttttttcgtt catctaaaag atacttacat ttaattaacg
      421 gatgttattc tatttaattg ttcgctagtt tttttataat gacatccctg aatttctcac
      481 ttgcttgtat tttgtacctt attctttgtt ggatatataa aaaaacaagt aaagcacatg
      541 ctttacttgt cttctgcctt tgcgatagga ataaagattc taaaaattgt cccttgccct
      601 actacacttt ctgctaagat acgtccttta tagttttcaa ccagttgttt agcgatagac
      661 aaccccagac catttccacc cttcgttcta gctcttgctt tatccactcg ataaaaacga
      721 ttgaagatct tattaaggtc ttctttgggt attccttcgc caaagtcctg aatcgcgatc
      781 tcaaattcat tcagagtgga agaaatagag atatggactt cttttcgtgt agttgaatac
      841 tttactgcgt tatccaatat gataatgatt aattgttcaa agtgattacg ataaatttgc
      901 agggtcactt cttttgtcaa atcatcatct aaagtgatca catagtctgg atataatatc
      961 ttgaaattat tataaacttg ataggtgact tcttttcctt tagttgtttc attcgcataa
     1021 tgaacatcta cttgttctgc tcttgataag tctagcatct cttgaactaa gcttttcata
     1081 cggctgattt cttgcatgct ggcgcttaat gattcttcta atatctcagg atcatctttc
     1141 ccccaacgat ttagcagact aagatgccct tcaataattg caacaggtgt ccttaactca
     1201 tgagatacgt cttccacgaa ttgctcttgt tgttcaatat acaaacgcat acggtcaagc
     1261 atctcattga atatttcagc taaatctgcc aattcatcat ttgtgtcgat ttcaggcatg
     1321 tggatatctg attgcggatc tttacgtata gtatccattg tatctctgag taccttgagt
     1381 ggttttaaga aataagaaga taaaaagaaa cctaaaatac tacttaagat caaagaaaca
     1441 acttctaaaa caataagagt caataatagc ttatttcgaa tatcatagaa agaagataat
     1501 tcatagaagc tttgcgcata gccgatcttt tctcttgtac ctttagaata tataggctgg
     1561 atagataaaa agccagtttt tccttctagt gtaacgatcg ttggaacttt acgtgtagtc
     1621 tgaatcaggt ttcgactgtt ttcatgggtt ttaaaaatca agttctcgtc caaatcataa
     1681 acataaagat ccattgatgg ctgccctagc tcagctataa aggaatcgat cttcattaag
     1741 tttccttcga ccagtgaagt atgatctacg acctcatctc cgtcatttgt cgctttcgtc
     1801 agattacgat acgtatttac taatgtcagt tcttcatccg agttagccaa acgagaagct
     1861 acttctgaaa tcgtacgctc tacattgttt ctttcttttg ccacaatcag attgatagat
     1921 gatttatagg taatgacagc gaaaattgta aacacaacga atatgaagaa agaactcgca
     1981 aaggcccact tgattgtcaa ggagggccct ttcagttctc ttttttccga ttttttcggc
     2041 tttatcacga gcgcatcaca taacctgttc cgcgtacagt ttggatatag ctttcctccc
     2101 cgggaacgtc aattttgttg cgaagataac gaatatatac gtccactacg tttgtttcaa
     2161 cttctgtttc gtatccccac actttattta gtaaaacgtc acgtgctaat accacgttca
     2221 cgttttccat taaagtaagc agcaactcgt attctctttt tgttagttca attacttcat
     2281 ttccgcgacg tacgacacgg ttttcttttt cgatagtcaa atcgcgataa gtaatagtag
     2341 tttgtttagc cacattttta tcgccttcaa tatcgattcg acgcaacaat gcacgaagac
     2401 gtgctaataa ttcttcgata gcaaatggtt tgacgatgta gtcatctgct ccgtggtcaa
     2461 gtccagatac acgatcgatc acagaatctc ttgcagtcat cataatgatt ggtgtatttt
     2521 tgacttggcg tacacgtctg cagacttcta aaccgttcaa ttctgggagc atcagatcca
     2581 acaatatggc atcccactca ttatttaatg ccgcatctaa accagttcgg ccgttgtagt
     2641 ggacttctgc gttataccct tcatgcttca actctagctc gacaaatcgt gccaagttct
     2701 tttcatcttc aatgattaga atattgctca tttattattt tatcctttct attctactgg
     2761 ctttttaaaa actctatcat tataccgata atatgcttaa aaatctatag tcattttatc
     2821 atggatagca attttaaaaa agagctgaag tctactcata acaatcgact tcagctcttt
     2881 cgtcctcttt ttattttctc atttcctaac agccgaaaga ctattattct tcatggtacc
     2941 atgagtaatg gaagattcct tctttgtcga cacgctcata ggtatgtgcg ccaaagtaat
     3001 cgcgttgggc ttggattata tttgcaggca gacgttctgc tctgtatgaa tcgaagtaag
     3061 cgatggctga tgagaaagtc ggtacaggta cgccagcttg gacagccaag gcaacgacgt
     3121 ctctgactga ttgctgatat tttttcgtga tttcaacgaa gtaatcatct agcaataaat
     3181 tttcgatctc aggatttttg tcataggcat ccgtaatttt ttgcaagaat cgagctcgga
     3241 tgatacatcc agcgcgccag atttttgcga tttcaccaaa tggcaagtcc caatcaaatt
     3301 cttttgaagc gacacgtaat tgatcaaatc cttgggcata actcatgatt ttactgaaat
     3361 acaacgcttc tcggattttt tcgaccaatt cttttttgtc tcccgtgaac tcaaaatcgt
     3421 tcgtacgaga caaaatcttg cttgcttgta cgcgttcttc tttataagca gaaatatagc
     3481 gggcaaatac agattcagtg atcaatggaa gtggcacacc taagtcaagc gcgctttggc
     3541 ttgtccattt acctgttcct ttattcccag ctgcatcaag gatcacatct actactggtt
     3601 tacctgttcc ttcatcgtct ttacgtgtca gaatgtcagc agtgatttct atcaaatagc
     3661 tgtctaattc gccttgattc cattctttaa agatatcagc catttcttct actgaaaggt
     3721 ttaaaatatt cttcattaag tcataagatt cagcaatcag ttgcatatct ccatactcaa
     3781 taccgttgtg taccattttc acataatgtc cggctccatt tgggccaata tatgtgacac
     3841 atggtgctcc gtcttctgct tttgcagaaa tttgctctaa gattggtgca actagcgcat
     3901 aggcttcttt ttgtccacca ggcatgattg aaggtccttt taaagctcct tcttcaccac
     3961 cggaaacgcc tgtaccgata aagttgatgc cagagttggc taactcttca ttacgacgca
     4021 tcgtatcttt aaagaatgta tttcctccgt caatcaaaat atcgccttta tcaaggtgag
     4081 gaagtaactc ttggattgtt gcatctgttg ccggtcctgc tttgaccatt agcaagatcc
     4141 gacgtggttt ctcgatagat tctacaaatt cttcgattgt atatgttgct ttgaaatttt
     4201 tatctgggtg ttcttctact acagcggttg ttttagcccc tgtacgattg aataaagcca
     4261 ctgaatagcc gcggctttct atgttcaagg ctagattttt acccataacg gccataccga
     4321 caacgccgat ttgttgtttt gacatatgaa ctcctcctac atacgggatt tctccctaat
     4381 ctcttacatt atagcttaac acggctacat tgcaaactaa agaacaacat att
//
LOCUS       DACGEU010000141         4413 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.146, whole genome shotgun sequence.
ACCESSION   DACGEU010000141 DACGEU010000000
VERSION     DACGEU010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4413)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4413)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4413
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.146"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            678..1646
                     /locus_tag="IXR40_002713"
     CDS             678..1646
                     /locus_tag="IXR40_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAQ4362499.1"
                     /translation="MDVAKTVNAIVEKNDGEISGIYLVACGGSLVDMYVSDYFLKAEA
                     SKCITGLYTANEFNHVTPKQLDDKSVVILCSHGGNTAETVKAGEVAQARGAVTVGLTH
                     NKTADLLKVSDHSFLYEWGDDAKIVNNPMAIILDLTVSLVNVTETFEHYGKFREGMKV
                     IDTVIENGIKQVQDRIKVFADKYKDETMFYILGSGPSYGHAYGFSICSLMEMQWLDST
                     SVHSGEFFHGPFEVTDKDTNFILLMSIGRTRALDERAKRFLDKYAERVEIVDAKELGL
                     DMISDEVSEFFNPILFYSILSEYRSALADARNHDLDVRRYMGKVEY"
     gene            1657..2472
                     /locus_tag="IXR40_002714"
     CDS             1657..2472
                     /locus_tag="IXR40_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructoselysine 6-kinase"
                     /protein_id="HAQ4362500.1"
                     /translation="MKVLGLGDNVVDKYENLGIMYPGGNSLNFAVFAKKLGHESSFMG
                     VFGSDEEAAHVLSAIKKIGLDNSHSRFEKGENGCARVKIDEGDRIFLGSNSGGVTREY
                     PIQLTEEDREYLNQFELIHMGLYSHVNHLLEELQNVSGKISYDFSDDFTEEEVQRAID
                     KVDFGFFSIEDFSDEEVKQFLMKHFCERNDVLIATRGEKTAIGYDGAKFYEVNPVLEE
                     PVDTMAAGDSFLTAFLLYFLEGDDIVTAMKKGNEFAGKSCLVDGSFGFGIHYD"
     gene            2540..3250
                     /locus_tag="IXR40_002715"
     CDS             2540..3250
                     /locus_tag="IXR40_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAQ4362501.1"
                     /translation="MLDTNAQLPLYLQLKEILKNKINTGEYPENTKIPAESELIESYE
                     VSRITVRKAVEELVEEGYLLKKQGKGTFVNRHKVFRKIEYVMGFSESCKSNGFTPTSI
                     VLERKIIPATEGMAKKLDIAQGDDVLYIQRKRMADNIPIMLENNYFSYERYSFLMEEE
                     LTDSLYEVLKVQGTLAINPGETALEIVTADDQIAKIMEVAVGTPFFFMDTLINDQNNI
                     PIHVGNQYYLGEVYRFYL"
     gene            3286..>4413
                     /locus_tag="IXR40_002716"
     CDS             3286..>4413
                     /locus_tag="IXR40_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HAQ4362502.1"
                     /translation="MKQVLRSKMIFDGEQPPFKGYIVINEGIIEKVENNWNYSDLLNE
                     NTELIAYDDQFVMPAIHDNHVFFSGYLAMNAGIDLSDTSSANEAVERIKAVMNHKKAD
                     EPIYAHGWDAALWKTDPSEELLNEINHFGPITAIDKNRSHCWMNAIAKQTYGFTEKET
                     SAESRVLLIKEMLANKKLLAEVYAEFEALLLSKGVISMKEIVFDDAEFLSNIPQRKIL
                     SNLYVQAVQEPLQHELLYEYKEKVFPEKVRFGGVKIMVDGVVADRSGDIYGVYQSGVA
                     SPEIDYEAIKAEVAAFNEVEIPCCLTTEGDKAGYKAASILVEFGKRLPEGVFNSISDL
                     EMVTQKTAEKMNEGQVVAEVYPQILGLNQTLEEAYMSTVIKN"
BASE COUNT         1484 a          661 c          918 g         1350 t
ORIGIN      
        1 tcaccaaaaa ggtgagtaat gccatttttg aaaattgagc ttgttttatg tctacatctg
       61 tatccgtata taatccaaag gattataaac tcagaagagt ctttattttt tctgaatata
      121 actactgtat caaaaacaat cgattatgag acaaaacaaa atgacctctt ttatttaaga
      181 aaggaggtca ttttttgtat cataaattgt attaaaatca atgtatcact ttttaatcaa
      241 ttttaagacc ataaattgcg tactaaaaga aattctgcaa ttcaaaataa agcattttaa
      301 gccattttca aatttaagtg cacccatcta cccgtcaaat cactttattt tccactccag
      361 tagtttccta attcaactgt gtgcaaaacg atttcttcta aacaaatcaa gacaaactta
      421 taaaccttca tcccagcacc ataattattt aaatcatagg catttttcga aattagtata
      481 tgtactcaag tttcactgca gattatttat attttttaga gaaataaatt tttcctattg
      541 acaaacacaa agaaagcgga tacaatacaa ttatgtcaca tgacgttata tgacgttatg
      601 taatatcttt acatttaatc agttactttt attttggata aaattaacat ttttaaaatt
      661 ttaaggagga aatgttgatg gatgtagcaa aaacggttaa cgcaattgta gaaaaaaatg
      721 atggagagat ttctggaatt tatttggtgg cttgtggcgg ttcgctggta gatatgtatg
      781 tctcagatta ttttcttaaa gccgaagcat cgaagtgtat tacaggctta tatacagcga
      841 acgaatttaa ccatgtaacc ccaaagcaat tagatgataa atctgttgtc attctatgtt
      901 ctcatggagg aaatacagca gaaacggtaa aagcaggaga agtcgctcaa gctagaggag
      961 ctgtgactgt tggtctgact cataataaaa ctgcggattt attaaaggtt tctgatcata
     1021 gtttccttta cgaatgggga gatgatgcaa aaatagtcaa taatcctatg gccatcattc
     1081 ttgatttaac tgtatctttg gtcaatgtta ccgaaacatt tgaacattac ggtaaattca
     1141 gagaaggcat gaaggttatc gataccgtaa ttgaaaatgg cattaagcag gtgcaggatc
     1201 gtattaaagt gtttgctgat aagtacaaag atgaaacaat gttttatatc ttaggtagtg
     1261 gaccatcata tggacatgct tatggttttt caatttgctc tttgatggaa atgcaatggc
     1321 ttgattcaac ttctgttcat tctggagaat tcttccatgg accttttgaa gtaacagaca
     1381 aagatacgaa ttttattctc ttgatgagca ttggacgcac tcgtgcttta gatgaacggg
     1441 caaaacgatt ccttgataaa tatgcagaaa gagtagaaat cgttgatgca aaggaactag
     1501 gattggatat gatatcagat gaagtttctg aattcttcaa tcccatttta ttctacagta
     1561 ttctttcaga atatcgttca gctttagcag atgcacgcaa tcatgattta gatgttcgtc
     1621 gctatatggg gaaagtggag tactaggagg attaaaatga aggtattagg cttaggtgat
     1681 aacgtcgtcg ataaatatga aaatctggga attatgtatc ctggaggaaa ttcattgaat
     1741 tttgcagttt ttgcaaaaaa actgggacat gaaagtagct ttatgggagt ttttggctca
     1801 gatgaggagg cagctcatgt tttatcagca ataaaaaaaa taggactgga caacagtcac
     1861 tctcgctttg aaaaaggcga gaatggctgt gccagagtga agattgatga gggcgaccgg
     1921 attttccttg gcagcaattc gggaggtgtt actcgtgaat acccgattca gcttactgaa
     1981 gaagacagag aatatttaaa ccagtttgaa ttgattcata tgggattata tagccatgtc
     2041 aatcatctat tagaagagtt acaaaatgtt tctggaaaga tttcttatga tttttctgac
     2101 gactttacgg aagaagaggt tcagcgggca attgataaag ttgattttgg cttcttttct
     2161 atagaagact tttccgatga agaagtaaag cagtttttga tgaagcattt ttgtgagcga
     2221 aatgatgtat tgattgcaac ccgaggagaa aaaacggcta ttggttatga tggagcaaag
     2281 ttttatgaag tgaaccccgt gctagaagaa ccagttgata caatggcagc gggagattct
     2341 ttcttaacag ctttcctact ttattttctc gaaggggacg atatagtcac cgcgatgaaa
     2401 aaggggaatg aatttgctgg gaagtcttgt ctggttgacg gttcgttcgg ctttggtatt
     2461 cattacgatt gagcttgttt taaattcctg catttgataa cctaaagaaa gaaatcccgg
     2521 taaagtggag gttaaaaaaa tgctggatac aaatgcacaa ttaccattgt acttacaatt
     2581 aaaagaaata ttaaaaaata aaatcaatac aggggagtat cccgagaata cgaaaattcc
     2641 cgctgaatca gagctgatag aaagttatga ggtcagccga atcacagtga gaaaagcagt
     2701 agaagaactg gtagaagaag ggtacctact taaaaaacaa gggaaaggaa cttttgtcaa
     2761 ccggcataaa gtttttcgta aaattgaata tgttatgggt ttcagtgaga gttgtaaatc
     2821 taatggtttt acaccgacta gcattgtttt ggaacgcaag atcattccag caactgaagg
     2881 gatggcaaaa aaactcgata tcgctcaagg tgatgatgtt ttatatatcc agagaaagcg
     2941 aatggcggat aacatcccca ttatgttaga aaacaattat ttttcttatg aaagatatag
     3001 tttcttaatg gaggaagagc tgactgattc tttgtatgaa gtacttaaag tccaaggtac
     3061 cttagccatc aatcctgggg aaactgcact tgaaattgtc acagctgatg accaaattgc
     3121 caaaataatg gaagtagctg ttgggacgcc ctttttcttt atggatactt taatcaacga
     3181 tcaaaacaac ataccaattc atgtaggtaa tcaatattac ctgggagaag tatatcgttt
     3241 ttacttatga tttcctgttt tgatttcaag gagtagattt tatttatgaa gcaagtattg
     3301 cggtcaaaaa tgatttttga tggagagcag ccacctttca aaggttatat tgtaatcaat
     3361 gaagggatca ttgaaaaggt ggaaaacaac tggaattaca gtgatctatt aaatgaaaac
     3421 acggaattaa ttgcttatga tgatcaattc gttatgccag caattcatga taatcatgta
     3481 tttttcagtg gttatttggc tatgaatgct ggcatagatt taagcgatac atcttcagct
     3541 aacgaggctg tagagcgtat taaagctgta atgaaccata aaaaagcaga tgaaccaatt
     3601 tatgctcatg gctgggatgc tgccctgtgg aaaactgacc catcagaaga gctattgaat
     3661 gaaataaacc actttggtcc aatcacagcg atcgacaaaa atcgcagcca ttgttggatg
     3721 aatgctattg ctaagcagac ttatggtttt acagaaaaag aaaccagtgc tgaaagtcga
     3781 gtattattaa ttaaggaaat gctagcaaac aaaaagcttt tagcagaggt ttacgctgaa
     3841 tttgaagcat tactgctttc aaaaggtgtt atatcaatga aagaaatcgt ttttgatgac
     3901 gcagaatttc tttctaatat acctcagagg aaaatactta gtaacctata tgtgcaggca
     3961 gtccaagaac ctctacagca tgaacttcta tatgagtata aggaaaaagt tttccctgaa
     4021 aaggtccgct ttggtggagt gaagatcatg gtagatggtg ttgttgcgga tagaagtgga
     4081 gatatttacg gtgtttatca gtcaggagta gcttcacccg agattgacta tgaggcaatt
     4141 aaagcagaag ttgctgcatt caatgaagta gagattcctt gctgtttgac aacggaagga
     4201 gataaagcgg gttataaagc tgcgtcaatt cttgtcgaat ttggaaagcg gttacctgaa
     4261 ggcgttttta attcgattag tgatttggaa atggttactc aaaagacagc agaaaaaatg
     4321 aacgaaggac aagtagtagc agaggtatat ccacaaattc tcggcttgaa tcaaacgtta
     4381 gaagaggctt acatgtcaac tgttataaaa aat
//
LOCUS       DACGEU010000142         4407 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.147, whole genome shotgun sequence.
ACCESSION   DACGEU010000142 DACGEU010000000
VERSION     DACGEU010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4407)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4407)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4407
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.147"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            <1..608
                     /locus_tag="IXR40_002717"
     CDS             <1..608
                     /locus_tag="IXR40_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362503.1"
                     /translation="ENQLFAGDVLEIVLNDQAGEAAAKGVQNKPSTNDEIGNHNPSDT
                     PVVYHDAPPFAPATKIVVEGGLSFLAPSKLDCGQIKATGLTQEAFGQMDIQEKLWIYD
                     QRETKSPWILTIKLSQPFTTDAGFSMQDVLYFKKAEEYQLVNEEELEIVRGQNSTNVQ
                     TDYSEYLNNGRAFKLVLTKENQIAGNYSAEMTWTLADAPTE"
     gene            628..1656
                     /locus_tag="IXR40_002718"
     CDS             628..1656
                     /locus_tag="IXR40_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HAQ4362504.1"
                     /translation="MNRIWNKSHRNNCSLLLILLLGFILWQTPVHASEFNFAVDFELP
                     ANQIDKNKTYINVRMEPGKTQEIPYTVFNRTDKSVTVETLIHSATTNSNGVIEYGESK
                     SKFDETLSYDMKNLAKTVGEITVPPQSAVTETLSLKAPEKELAGVVAGGITFQEKKEN
                     VSNKSTVGVVNQFSQVKAILIRNSEKESSPNLKLKKTYADQSDGRNVIKANLQNPNAS
                     YMFGLTTSVEIYKKETKEPYLSIKKEKIDVAPNTNFDLLVPLEGKKLAPGHYQAVVKG
                     AWKEKRWNLHTDFEITDDAADQLNEKDIDLKNQPETFDWRWLILVGVILIGLFAGLFI
                     LKERRKKK"
     gene            1653..2411
                     /locus_tag="IXR40_002719"
     CDS             1653..2411
                     /locus_tag="IXR40_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HAQ4362505.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPNEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QNGTDSTGTATQVQNFVQVTDKSGIYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGTPSTISGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEGKA"
     gene            complement(2497..3237)
                     /locus_tag="IXR40_002720"
     CDS             complement(2497..3237)
                     /locus_tag="IXR40_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4362506.1"
                     /translation="MKKYFIIEDNQFHSEWIIKELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            3298..>4407
                     /locus_tag="IXR40_002721"
     CDS             3298..>4407
                     /locus_tag="IXR40_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAQ4362507.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGFIALMVVTLL
                     FPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGLRFSIANKANPTNLTLSEMVKRGKTSKK"
BASE COUNT         1481 a          768 c          840 g         1318 t
ORIGIN      
        1 cagaaaatca actttttgca ggagatgtat tagaaattgt attaaacgac caagcaggag
       61 aagctgctgc taagggtgtg cagaacaagc caagtaccaa cgatgaaatt gggaatcaca
      121 atccaagtga tacgccagtt gtttatcatg atgccccgcc ttttgcacct gctacgaaga
      181 ttgtagtaga aggtggtctc tcatttcttg ccccttccaa actcgattgt ggtcagatca
      241 aagcaactgg gttgacgcaa gaagcatttg gccaaatgga tatacaggaa aaattatgga
      301 tttatgatca gcgagaaaca aaaagtccat ggatcttaac gataaaatta tctcagcctt
      361 tcacaaccga tgcaggattt tctatgcagg atgtcctata tttcaagaaa gctgaggagt
      421 atcaattagt gaatgaagaa gaactggaaa ttgtcagagg acaaaattca acgaatgtgc
      481 aaacagatta ttcagaatat ttaaataatg gtcgggcgtt taaacttgtc ttaaccaaag
      541 aaaatcagat agctggtaat tactcagcag agatgacatg gacattagca gatgcgccga
      601 cagaataaag atcaaggaga atgattgatg aatcgaatat ggaataaaag tcatcgaaac
      661 aactgctctt tacttctgat ccttctcctt ggattcatcc tttggcagac acctgtccat
      721 gcctccgaat tcaattttgc ggtagatttt gaattaccgg ctaatcagat tgataagaac
      781 aaaacatata taaatgtaag gatggagcct gggaaaacac aggaaatccc ctacacggtc
      841 tttaaccgaa cagataaatc agtaacagtt gagacattga tccactccgc tacgacgaat
      901 tcaaacggtg tgatcgaata tggagaatca aaaagtaaat ttgatgaaac attaagttat
      961 gatatgaaaa acttagcaaa aacagtggga gaaataactg tccctcctca aagtgcggtc
     1021 actgagacac tttcactgaa agctccagaa aaagagctgg ctggtgtggt cgcaggagga
     1081 atcacgtttc aagaaaaaaa agagaacgtt tctaacaaaa gtacagttgg tgtcgtcaat
     1141 cagttttctc aagtgaaagc aatcttgatt cgaaatagcg aaaaagagtc ttccccaaat
     1201 ttgaaattaa aaaaaactta tgcggatcaa agcgatggaa gaaatgtgat taaggcgaat
     1261 cttcaaaatc caaatgcttc ttatatgttc ggcttgacta catcggttga aatctacaaa
     1321 aaagaaacaa aagagcctta tctttcaata aaaaaagaaa aaatagatgt agcacccaat
     1381 acaaattttg atttacttgt cccattagaa ggaaaaaaat tagctccggg acattatcaa
     1441 gcggttgtga agggtgcttg gaaagaaaaa cgctggaatc tccataccga ttttgaaata
     1501 actgatgatg cagcggacca attgaatgaa aaggatattg atttaaaaaa tcagccagaa
     1561 acatttgact ggcgatggct gatacttgtt ggagtcattc ttattggctt atttgctgga
     1621 ttatttattt taaaagaaag aaggaaaaag aaatgaaaaa aacaattgca ttaagtaccg
     1681 ttctagctgg aagtctatta ttatgtacac aaagtgtttt tgctgagaat aagagctcag
     1741 ccactacaga aggaacgatt tctgtaacaa aaccagatgc cgcaaatcct gaagacgttg
     1801 ttccagttcc tcctgttgat ccaaatgatc ccgatacgcc gtttacacct aacgaaccaa
     1861 atcagggaac atccggatta ctgacgattg accaagctcc agatcttgat tttggaacaa
     1921 tcaagttagg tacagcaaaa acagtatatg ctgcattaca aaacggaacg gacagtacag
     1981 ggacagcaac acaagtacag aatttcgtac aagtaacgga taaaagcgga atttatgccg
     2041 gttggaaact atcagtcaaa cgaacagaat ttattggtac aacatctgat acgaataaac
     2101 taactggttc aaaggtgaaa ttcaaaaacg ccgtgattcg aaatagcgca actaatagca
     2161 gtggaacgcc atctactatt tctggtactg gcgctgaagg aattgagatc ccagcagatc
     2221 aggcagtaga tctagtaact gcaggagcaa atgaagggat tggcacatgg atttattcat
     2281 taggagagaa tgtggaacaa gggagacaat cagtggaatt atttgttcct gtatccaatt
     2341 atgccgtaga caactacgtt tcaacattca catggtcgtt aacagatgct cctacagaag
     2401 ggaaagcgta aaatcaaatc aatgacttca gggagtggag ccgattcaag gccaactccc
     2461 tgaaatctgc tatgcttacg tctcagctct tattcatcaa ctcgaagcag ttttttggaa
     2521 gtcatggaaa cgttcctttg tcttttcaaa gatctttcga ccaacgagta aggagtcacc
     2581 attgaaaaat tctaacacat aatgagcaga atcaattttc tgcaattgcg ataagttgat
     2641 acagtaagat tttaatagta aaaagtaagc atacttttcc aactctgtct tcaattgttt
     2701 taaagaagta ttcactaatt tatcttctgt agttgttttg accataactt ggtttttcaa
     2761 acctttgata ctttcaatat ataaaatttc ccgaggatac aggacgagac ttccaccttt
     2821 ttgatcaata aagattttat cgacatttac gatttgctgt tctttccaat tgatctgttc
     2881 tagcacttga cgaatttgtt cagataaatt cctgtctttt ctgatatatc caatcggaag
     2941 gattttccga ttgatgatct ctactgcaaa attcgtataa gcggtgaaaa aaacaatatt
     3001 actatgtgca ttttttttac gtatttgttc ggcgacatca atacctgtga gtgattgctt
     3061 caagtcgata tcgataaaga aaacatcgtg attatcaata gtacccaact ggatcaactg
     3121 attgatttga gagatagaag tgagctgcac gatattctcg atatgatgat tgaccaattc
     3181 tttgatgatc cattcgctgt gaaactggtt atcttctatg ataaaatact ttttcatatg
     3241 caggctccta ttaaaaaaat atgtgtacat tttgaaacaa aacaatggag gaataagatg
     3301 gtcgcaacag tgacacttta tttgaccttt actttgattt tagatttagg tatctattta
     3361 ttcttttcga aacaactgct agtaaaaaac agctttggtt ttatagcttt gatggtggtg
     3421 acacttttat ttcctatccc taaagtgagc tttccttacc tagttggctt attattgatg
     3481 tttctttttt attttactac gaaaaacctg tttatcagct gtttgatcag taatcttttt
     3541 tttgctatca ctggactcag cttttttctg gtttttgatc tgatggatta tttaggaaag
     3601 agacatcttg gaacagcaag tttttttgca ctacttatcg catttatttt ctatctatta
     3661 gtaaaaagta tagacaaaca gacgagattt ctcaacttgc tttttactta tccaactgaa
     3721 cactattttg gaggtatttg tattttatta agctggggcg tgatttactt ggtattggga
     3781 agtgttcact tccgctcatc taattatctg cttctatctc ttttgtcgat agtcatcagt
     3841 tttttttctt tgtttttttc cattatgttg atcagtttcc aagtaaaaga aagacaacat
     3901 caggaatcgc ttcaactgta tcaaataaat gaagaatatt accatcatct agaggaattc
     3961 aaacatgatt ataaaagtct actgttttca ttaaaaatta ctcttcagga aaataaaaaa
     4021 gaaacgttgg aatttttaga aatcttagaa gatcattctg cagctatttt tgaaaaaccg
     4081 caaatacaac agctaacaaa tattgtatcc ccagctgtca ggggtgtctt tttaaaattt
     4141 ctagaaaaag cagaatcgga gaaaatcccg atccaagtag ttattcctgt cgaagtgaaa
     4201 acaatcccga ttgatctggt tgtttttatt cgctgtttat ctatttttat ttctaacgca
     4261 ttcgatcatc gtgtagccga tcagagtccg attacgatca atctgctgga agaaaaagag
     4321 ggattacgtt ttagtatagc gaacaaggca aatccgacga atttgacgct atcggagatg
     4381 gtcaaaagag gaaaaacctc taaaaaa
//
LOCUS       DACGEU010000143         4242 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.148, whole genome shotgun sequence.
ACCESSION   DACGEU010000143 DACGEU010000000
VERSION     DACGEU010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4242)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4242)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4242
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.148"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            85..1716
                     /locus_tag="IXR40_002722"
     CDS             85..1716
                     /locus_tag="IXR40_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HAQ4362508.1"
                     /translation="MVSIKNWQNSIEEFNEMQILLPCFDVKEVKQEGQQHPVWLHFGG
                     GNLYRGFHAEIAQCLADQNELETGVVVCETFDEEVVEKAYHDYNNDILEIVMSGDGEL
                     KKRLLAVTADSLYCNPKNIADYQRVVKYFEDPKLQFTTFTITEKGYSLKDSKGQFFSV
                     VKADIKSGPSNPQHTMSIVTSLLYSRFNAGELPIAMVSTDNFSQNGQRFQDSIFTIAE
                     AWQKEGYVSEKFIAYLKDKEKVTFPWSMIDRITPNPSENVKEDLLMMGLEDLDIIHTK
                     KHTNIAAFTNTEVVHYLVIEDSFPNGRPKLEKAGVIMTDRETVDKADIMKVTTSLNPL
                     HTALAVTGCLLGYQSISAEMQDDDLVGLIKGIGYLEGLPVVENPGIIDPKQFIDEVIN
                     KRLPNPYIPDTPQRIATDTSQKVAIRYGETIKKYVEKDGNAENLTFIPIAIAAWLRYL
                     LAVDDQGENFVPSPDPLLVELQDKLSVLKLGEQDPSKIHCAVQEILENKEIFGLDLYQ
                     VGVGKKTEKIFCEMLVGPQAVRKTINKYITEVGGK"
     gene            1719..2798
                     /gene="uxuA"
                     /locus_tag="IXR40_002723"
     CDS             1719..2798
                     /gene="uxuA"
                     /locus_tag="IXR40_002723"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HAQ4362509.1"
                     /translation="MEMTFRWYGANEEKISLQEIRQIPAMKGIVGTLMDIPAGEVWPR
                     ERIKSLKDEVEANGLTLKVIESVNVHDDIKIGLPTRDQYIENYKQTIRNLAEFGIEVI
                     CYNFMPVFDWVKSDLDYRLDDGSSTLAYISKNIPTDPEEIIREVENSTNNFELPGWEP
                     HRLSQIKQLLEAYKEVDEEKLRENFAYFLKAIIPTCEEVGIKMAVHPDDPPYSIFGLP
                     RIVKNRDDLDWLCNVVDSPSNGITLCTGSIAERPDNDVYEILSEFCQRDRIPFAHVRN
                     IKYLSDNGLDFYEAPHKSEYGSLDMYKILKTMYDNGFNGYIRPDHGRMIWGETGRPGY
                     GLYDRALGAVYLNGIWEALEKGASK"
     gene            2872..>4242
                     /gene="uxaC"
                     /locus_tag="IXR40_002724"
     CDS             2872..>4242
                     /gene="uxaC"
                     /locus_tag="IXR40_002724"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019239247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HAQ4362510.1"
                     /translation="MFLDKNFLLENEIAKRLFHKFAKHQPIIDYHCHLDPAYLLENKQ
                     YKNLTQVWLNDKGAGDHYKWRLMRANGIEEELISGPGDDYEKFLAFVKTVEKAPGNPI
                     FEWSHLELQRYFDIDLTISEKNAPEIWRRANEKIQTDSYRPKELLEMMDVKAICTTDD
                     PTDDLWYHTELSKQDNSFKVLPTFRPDKVWSIKSSGFSNYILKLSQTAAIPIKDFNGL
                     KQALSQRVDHFHQIGCRLADHGLNTYFYEIADEKILDNLLIKALAGKTDFHLSEIAQF
                     VTGIQLHLMSEYTRYGWTMQMHLNALRNNSSILKEQIGVDVGGDSMGDQASLTQNVVA
                     LFDTAEKSGCLPKTILYSLNPTDWLPLATAMQSFQGGMIQKIQLGCAWWFNDTAEGMR
                     QQLTTMAQQSLLSNFTGMLTDSRSFLSYPRHEYFRRVLCQLLSEWVKAGRIPDDEMYL
                     SQIVENI"
BASE COUNT         1453 a          598 c          892 g         1299 t
ORIGIN      
        1 ccctttttat attgacaacg gttacaatgg gttttaaaat ataaaatgta tcaaaactaa
       61 catatcagtt tgaggaggtt aattatggtt tcgattaaaa attggcaaaa ttctatcgaa
      121 gaattcaatg aaatgcagat tctactgccg tgttttgatg tcaaagaagt taagcaagaa
      181 ggccagcaac atccagtatg gcttcatttt ggtggaggaa atctttatcg aggatttcat
      241 gcagaaattg ctcaatgctt agcagatcaa aatgaattag aaacaggagt agttgtgtgt
      301 gaaacatttg atgaagaagt agtggaaaaa gcttatcatg actataacaa tgacattttg
      361 gaaattgtta tgagtggaga tggtgaactc aaaaaaagac ttttggcagt aacggctgat
      421 agtttatatt gcaatccgaa gaatatagcg gactatcaaa gagtggttaa atattttgaa
      481 gatcctaaat tacagtttac aacgtttact attactgaaa aaggttacag tttaaaagat
      541 tctaaagggc aattcttttc ggtagtcaaa gctgatatca aatctggacc tagcaatcct
      601 caacatacga tgagtattgt aacatccttg ttatatagca gatttaatgc tggagagttg
      661 ccgattgcga tggtttctac tgataatttc tcacagaatg gtcaacgttt tcaagatagt
      721 atttttacga ttgcagaagc ttggcaaaaa gaaggatatg tttctgaaaa atttattgct
      781 tatttaaagg ataaagaaaa agtgactttt ccttggagta tgattgatcg aattacgcca
      841 aatccttcag agaatgtaaa ggaagatcta ttgatgatgg ggctcgagga tttagatatc
      901 attcacacaa aaaaacatac caatattgct gctttcacta atactgaggt agttcattat
      961 ttagttattg aagatagttt tccaaatggc cggcctaaat tggaaaaggc tggtgtgatt
     1021 atgacagata gagagacggt tgataaagca gacatcatga aggttacgac aagcttgaat
     1081 ccacttcata ctgctttggc agtaacaggt tgtctgctag gatatcaatc aatttcagca
     1141 gagatgcagg atgatgattt ggttggttta atcaaaggaa taggttattt agaaggttta
     1201 ccagtagttg aaaatccagg cattattgat ccaaaacaat ttattgatga agtaattaat
     1261 aaacgtttgc ctaatcccta tattccagat acaccacaac gaattgcaac agatacttct
     1321 caaaaagtag cgattcgcta tggtgaaaca attaaaaagt atgtcgaaaa agacggaaat
     1381 gcagaaaatc taacatttat tcctatcgct attgctgctt ggttacgtta tttactggca
     1441 gtcgatgatc aaggggaaaa ttttgtgcca agtcctgatc cgttattggt agagttgcag
     1501 gataaattat cagtattgaa attaggtgaa caagatcctt caaagattca ttgtgcggta
     1561 caggaaattt tagaaaataa agaaatcttt ggtttagatt tatatcaagt tggggtagga
     1621 aagaaaactg aaaaaatctt ttgcgaaatg ctagtaggtc ctcaagcagt tcgtaaaaca
     1681 atcaataaat atataacaga agttggagga aagtaactat ggaaatgact tttagatggt
     1741 atggggcaaa tgaagaaaaa atctcactac aagaaattcg tcagatccca gcaatgaaag
     1801 gaattgttgg aacattaatg gatataccag ccggagaggt ttggccgaga gaacgaatta
     1861 aatctttaaa agatgaagtc gaagccaatg gacttacctt gaaagttatt gagagtgtta
     1921 atgttcatga tgatatcaaa attggtttac caacacgaga tcaatacatt gagaattata
     1981 aacagacgat tcgcaatttg gcagaatttg ggattgaggt tatctgttat aattttatgc
     2041 cagtatttga ttgggtaaaa tcggatttgg attatcgttt agatgatggg tcttctacgt
     2101 tagcctatat ttcaaaaaat atccctactg atccggagga aattattaga gaagtagaaa
     2161 attctactaa taattttgaa ttgccgggtt gggaacctca tcggttatca caaattaagc
     2221 aattattaga agcctataaa gaagttgatg aagagaaatt acgagagaac tttgcatatt
     2281 ttctcaaagc aattatcccg acatgtgaag aagttgggat taaaatggca gttcacccag
     2341 atgatccacc atattccatt ttcggattac ctcgtattgt taaaaatcgt gacgatttag
     2401 attggttgtg taatgtagtg gattctcctt ctaatggtat tacattatgt actggaagta
     2461 ttgcagaacg accagataat gatgtctatg aaattctatc tgaattttgt caacgggatc
     2521 ggattccttt tgcacatgtt cgtaatatca aatatttaag tgacaatgga ctcgattttt
     2581 acgaagcgcc gcataaatca gaatatggtt ctctagatat gtataagata ttaaaaacaa
     2641 tgtacgataa tggatttaat ggctatattc gtccagatca tggtcggatg atttggggag
     2701 aaaccggtag acctggttat ggattatatg accgagctct aggtgcagtt tatttaaatg
     2761 gtatttggga agcgcttgaa aagggggcga gtaaataatt atataaggga gtttatttag
     2821 aggaaaaatt ttctcttcta aaaactaacg gaaggaaagg agtgtttaaa tatgttttta
     2881 gataagaact ttttattaga gaatgaaata gctaaaagac tttttcataa atttgcaaaa
     2941 caccaaccaa ttatcgacta tcattgtcat ttagacccag catatttgct agaaaataag
     3001 caatacaaga atttgactca ggtatggtta aatgataaag gagctggaga tcattataaa
     3061 tggcgattga tgcgagctaa tggtatagaa gaagagttga tcagtggtcc aggtgatgat
     3121 tatgaaaaat ttttagcttt tgtaaaaaca gtggagaagg cgccaggtaa tcctattttt
     3181 gaatggtctc atttggaatt acaacgttac tttgatattg atttgacaat ttctgagaag
     3241 aatgcaccag aaatttggcg acgtgctaac gaaaaaattc aaacggattc ctatcgcccg
     3301 aaagaattgt tggagatgat ggatgtgaaa gccatctgta caacggatga tcctacagat
     3361 gacttgtggt atcatactga gctttctaaa caggataatt ctttcaaggt attacctact
     3421 ttccgtccag ataaggtctg gagtatcaaa tcatcaggct tttcgaacta tattttaaaa
     3481 cttagtcaaa cagcggctat accaatcaaa gactttaatg ggttgaagca agcattgagc
     3541 caacgagtgg atcattttca tcaaattggc tgtcgattag cagatcacgg tttgaatact
     3601 tatttttatg aaatagcaga tgaaaaaata ctcgacaatc tgttaataaa agctttagca
     3661 ggaaaaacgg atttccattt atcagaaatt gcacaatttg ttacaggtat tcaattacat
     3721 ttgatgtctg agtatacaag atatggttgg acgatgcaaa tgcatttaaa tgctttaaga
     3781 aataattcaa gtatattaaa ggaacaaatt ggagtagatg tcggtggtga ttcgatgggg
     3841 gatcaagcta gtttgacaca aaatgttgta gcattgttcg ataccgctga aaagagtggg
     3901 tgcttaccaa aaacaatttt atattcatta aatccaactg attggcttcc actagcaaca
     3961 gcaatgcaaa gcttccaagg gggtatgatt caaaaaatcc aattgggatg tgcttggtgg
     4021 ttcaatgata cagctgaagg aatgcgtcaa cagttgacta cgatggcaca acaaagtttg
     4081 ttgtcgaatt ttacaggtat gttgactgat tctcgaagtt ttctaagcta tcctcgccat
     4141 gagtattttc gtcgagtatt atgtcaatta ctaagcgagt gggttaaagc aggccgaatt
     4201 ccagatgatg aaatgtatct tagtcagata gtggagaata tt
//
LOCUS       DACGEU010000144         4125 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.149, whole genome shotgun sequence.
ACCESSION   DACGEU010000144 DACGEU010000000
VERSION     DACGEU010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4125)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4125)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4125
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.149"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..210)
                     /locus_tag="IXR40_002725"
     CDS             complement(<1..210)
                     /locus_tag="IXR40_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAQ4362511.1"
                     /translation="MDTITPTNFKENIGKVLQEVVHSNSEIEITRDSKNGLNDGVIMI
                     SKRKWELLQEELYLQRTGTWAYVSDL"
     gene            complement(309..623)
                     /locus_tag="IXR40_002726"
     CDS             complement(309..623)
                     /locus_tag="IXR40_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362512.1"
                     /translation="MAEENKVVPFETLVINKEEFEQLFLDFFIQYDMIYDFSSSLDLF
                     ELEAEIIENSREKNGKIIISVEKFNELFSQTFEIDPDYYQPQEVFREFRNKIIGFSQT
                     TK"
     gene            complement(691..1185)
                     /locus_tag="IXR40_002727"
     CDS             complement(691..1185)
                     /locus_tag="IXR40_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362513.1"
                     /translation="MFKVYFPFQWLVKGILLVLLGLILFGSYLTIKARHFPEEKPIKI
                     VTKDLKIGETYQADGVELTFKNIEVTEKRNEFAQHDRVLQVTYTLINDTENPIRPQQW
                     SIENKDGEELYEYDMILDNPEYIESGKEETVNYYYELPIERQDYQIVVRRENGYIVGL
                     PFTL"
     gene            complement(1178..1492)
                     /locus_tag="IXR40_002728"
     CDS             complement(1178..1492)
                     /locus_tag="IXR40_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362514.1"
                     /translation="MNYPYFKVSASEETKEIFNNFYNQNKGIFGSKANMFRVMVSNLP
                     VLASPSNNKFNDPESIKFEQKISELESMISNEVIEKLDDIDQKLSYSLKNKYKTEEKK
                     DV"
     gene            complement(1708..3099)
                     /locus_tag="IXR40_002729"
     CDS             complement(1708..3099)
                     /locus_tag="IXR40_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HAQ4362515.1"
                     /translation="MGATITSKGRKKNLSSLLQYAANPSKKEKCVAVSGINCSDDSEE
                     ALQEMNLVRTKMNKSKDIAQAFHVIHSFDKSTSKELSIDKMHEIAVEFAEKAFPNSQI
                     IVASHNDKDHFHSHLVINNINMETCKRLRIDPKDLELMRKINDQVLNEHGLESVNNEY
                     YENLEKRTNLYSNDPSKMKYGKINYQEFVQNAIEATLEKCEVNSFEDFSDHLAKEYNI
                     EVYQFSKTNNKLGYVLYKQGVNFYERRGELITLGRDKQSRKEKSQYVERTFSARKLGK
                     RYSFESVSEQLEKNLEESHIKNFFNMEREQVMSLISGVNYKTGELNVPFVELDSIAQK
                     QFSDREGDEKFIKYDDFLREVDKHFVNTMSLEDDQEYTIKLHTDVNPQTLRSAKSKTI
                     SIKKTDQKELFLPAKGFENCSHTPSAKQIHYQISRIMNDDVKMYRAKKDYEFTQQMIE
                     NQQKRQQNFEMEF"
     gene            complement(3084..3695)
                     /gene="mobC"
                     /locus_tag="IXR40_002730"
     CDS             complement(3084..3695)
                     /gene="mobC"
                     /locus_tag="IXR40_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HAQ4362516.1"
                     /translation="MDDKQKMYEKNRKHSEALNFRVDKKTYLELTLIAKQRGISRADV
                     CRERLKGLKYEPPLLAEDDRVVLTKQLNQIGNNLNQAVKALNIIAKYFREESEDKKEK
                     SLHFSFDASRYNIFKDELANSIAKKLMISYPDDIFLESNRSAPSFFKLSEVEKEYFEY
                     WIEKQTRPGTKEEYSQKVDRNLIHSIQIIASLKDEVKQLWELL"
     gene            complement(3699..3896)
                     /locus_tag="IXR40_002731"
     CDS             complement(3699..3896)
                     /locus_tag="IXR40_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362517.1"
                     /translation="MQLILNISTHDFLELDELCESVKNATNEKITVTNYIELMIQEEL
                     KMKNEIESNFKCCSLEKNVRG"
     gene            complement(3887..>4125)
                     /locus_tag="IXR40_002732"
     CDS             complement(3887..>4125)
                     /locus_tag="IXR40_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362518.1"
                     /translation="KEKTQKINIVEDRKSAKKFDSNHETVIIDSEIRENDKGSKSRRR
                     FTYEDNELFRDTLNDPNPLFDNLLRNKRGGLSCN"
BASE COUNT         1197 a          771 c          548 g         1609 t
ORIGIN      
        1 taaatcagat acataagccc atgtacccgt tcgttgtaaa taaagttctt cttgtaacaa
       61 ctcccatttt ctcttagaaa tcataatgac gccatcgttc aatccatttt tagaatccct
      121 agtaatttct atttcagaat ttgaatgaac tacttcttgc aacactttac ctatattttc
      181 tttgaagttt gttggagtaa tagtatccaa aatgaatacc tctcttctct atacctctat
      241 tatgaagtgc ccataaaata aagcaagcgt tgaggaataa ttctatcaac acttgcttta
      301 ttaagctttc attttgtagt ttgactaaaa ccaataatct tatttctaaa ctctcgaaaa
      361 acttcttgtg gttgataata gtctggatct atttcaaatg tttgtgagaa taattcattg
      421 aatttttcta ctgaaataat gattttacca ttcttctctc gactgttttc tattatttct
      481 gcttctaatt caaataaatc tagtgacgaa ctaaaatcat aaatcatgtc atattgaata
      541 aaaaaatcaa gaaaaagttg ctcaaactct tccttattta tcactaatgt ttcaaacgga
      601 acaactttat tttcctcagc cattctccca gttccatttt caaaaatcac aaaactgata
      661 ttaccttaaa aactactaac aaaataaaac ttataaagta aatggcaacc caactatgta
      721 accattctct ctacgtacta cgatttggta gtcctgcctt tcaatcggta attcataata
      781 gtaatttact gtttcttctt tgccactttc aatatactct ggattatcca atatcatatc
      841 atactcataa agttcttcac catccttatt ttcaatcgac cattgttgtg gacgtatcgg
      901 attttctgta tcatttataa gtgtataggt cacttgtaat acacgatcat gttgtgcaaa
      961 ttcatttctt ttttcggtca cttcaatatt tttaaatgtt agttcaaccc catctgcctg
     1021 ataagtttca cctattttta aatcttttgt tacaattttt attggctttt cttctggaaa
     1081 atgtctggct ttaattgtta gataacttcc aaaaagaatc aatcctagta gcactaaaag
     1141 aattccttta acgagccact gaaacgggaa gtaaacttta aacatctttt ttctcctccg
     1201 ttttgtattt gttttttaga gaatacgata acttttgatc aatgtcatcc agcttttcaa
     1261 ttacttcatt acttatcatt gattctagtt ctgaaatttt ttgttcaaat ttaatgcttt
     1321 caggatcatt aaatttatta tttgatggac tagctaacac tggtaaattt gaaaccataa
     1381 cacgaaacat atttgccttt gaaccaaaaa ttcctttgtt ttggttgtaa aaattgttga
     1441 atatttcttt agtttcttct gaagccgaga ctttaaaata tggatagttc atttttttct
     1501 tccacctttc tttttttggg agggagtctg tagggagctt gctccctcag agatttaccc
     1561 gccatctgac ttgccagaaa gtagcctagc gtgagcgggg cggattgact ggcaagtaga
     1621 tgggtagctg gcgtatgtcc taaaaactgc ttctttccaa gcaactcttc ataggcaaaa
     1681 aactggaaag tccactaaca agcccattca gaattccatt tcaaaatttt gttgcctttt
     1741 ttgctgattt tcaatcattt gttgtgtgaa ttcataatcc tttttagcac gatacatttt
     1801 tacatcgtca ttcattatgc gactgatttg atagtgaatc tgtttagcag aaggtgtatg
     1861 agaacaattt tcaaaaccct ttgccggtag aaataactct ttctgatcag tctttttaat
     1921 agaaattgtt ttacttttcg cactacgtaa agtttgagga ttcacatccg tatgaagttt
     1981 aatcgtgtat tcttgatcat cttctaaaga cattgtattt acaaaatgct tgtctacctc
     2041 tcgcaagaag tcatcatatt taatgaattt ttcatcgcct tcacggtcgc taaattgctt
     2101 ttgtgcgatg gaatctaatt ccacaaacgg tacatttaac tcaccagttt tgtaatttac
     2161 tccactaatt agcgacataa cttgctctct ttccatatta aaaaaatttt ttatatgtga
     2221 ttcttctaaa ttcttttcaa gttgttcaga aacagattca aatgaatatc ttttccctaa
     2281 ctttcttgca ctaaaagtac gttcgacata ctgacttttt tcttttctag attgtttatc
     2341 tcttcctaaa gtaattaact cacctctacg ctcatagaaa tttacacctt gtttgtaaag
     2401 aacatagcca agtttgttat ttgtttttga aaattgataa acttcaatgt tatattcttt
     2461 tgccaaatga tccgaaaaat cttcaaaaga attcacttcg catttttcca acgttgcttc
     2521 gatcgcattt tgcacaaact cttgataatt aatttttcca tatttcatct tagaaggatc
     2581 gtttgaataa agattggttc tcttttctaa gttttcatag tactcattat tcactgattc
     2641 aagaccatgt tcattgagga cttgatcgtt aatttttcgc attagttcta aatctttagg
     2701 gtcaatacgc aaccttttac atgtttccat gttaatatta ttaatgacaa gatgactatg
     2761 aaaatgatct ttatcattgt gacttgcaac aatgatttgc gaatttggaa aagctttctc
     2821 tgcaaattcg acagctattt cgtgcatttt atcaatactt aactctttag aagtactctt
     2881 atcaaacgaa tgaataacat gaaacgcttg tgctatatct ttagatttat tcatcttggt
     2941 acgtactaaa ttcatttctt gcagtgcttc ctcactatca tcactacaat ttattcctga
     3001 gactgcaaca catttttctt tttttgaagg attagctgca tattgtaata gcgaggataa
     3061 atttttcttg cgtcctttcg atgttatagt agctcccaaa gttgtttcac ctcatctttt
     3121 aaacttgcaa taatctgaat tgagtgaatt aaattccgat caactttttg ggaatactct
     3181 tctttcgtac ccggtctagt ttgcttttct atccaatatt cgaaatattc tttttctact
     3241 tctgataatt taaaaaaaga gggggcactc cgattggact ccaaaaaaat gtcatctgga
     3301 taactaatca tcaacttttt tgctatgcta ttcgcaagtt catctttaaa aatgttgtaa
     3361 cggctagcat caaaactaaa atgtaggctc ttttcttttt tatcttcaga ttcttctcta
     3421 aaatatttag caatgatatt taatgccttt accgcttgat tcaaattgtt accaatttga
     3481 tttaactgtt tggttaaaac taccctatca tcttcagcta acaacggcgg ttcatatttg
     3541 agtcccttta accgctcacg gcaaacgtct gctctagaaa ttcccctttg ttttgcaatc
     3601 aatgtcagtt caagataagt ctttttatcg acacgaaaat ttaaggcctc actatgtttg
     3661 cgattttttt cgtacatttt ttgtttatca tccattgatt atcccctcac atttttttct
     3721 agagagcaac atttgaaatt gctctctatt tcatttttca tctttaattc ttcttgaatc
     3781 atcagttcaa tataattagt gaccgtgatt ttttcatttg ttgcgttctt tactgattca
     3841 cataattcgt caagttctaa gaaatcatgc gtactaatat ttagaattaa ttgcatgaca
     3901 atccccccct tttatttctt aataaattat cgaaaagtgg attaggatca ttaagtgtat
     3961 ctctgaataa ctcattgtct tcataagtga atcttcgtct tgattttgat cccttatcat
     4021 tttcacggat ttcactatca ataatcactg tttcatgatt tgaatcaaat tttttcgctg
     4081 actttctgtc ttcaacgata ttgatttttt gtgttttttc tttca
//
LOCUS       DACGEU010000145         4071 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.150, whole genome shotgun sequence.
ACCESSION   DACGEU010000145 DACGEU010000000
VERSION     DACGEU010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4071)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4071)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4071
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.150"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            87..1436
                     /locus_tag="IXR40_002733"
     CDS             87..1436
                     /locus_tag="IXR40_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAQ4362519.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(1564..2154)
                     /locus_tag="IXR40_002734"
     CDS             complement(1564..2154)
                     /locus_tag="IXR40_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HAQ4362520.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVLVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            2301..3653
                     /gene="brnQ"
                     /locus_tag="IXR40_002735"
     CDS             2301..3653
                     /gene="brnQ"
                     /locus_tag="IXR40_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HAQ4362521.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
BASE COUNT         1176 a          744 c          790 g         1361 t
ORIGIN      
        1 gaaaattttg gaatcttagt tgtgtttttc agaaaactct cttaatatgg aagtaattaa
       61 acttttttag ttaggatgat ttaaaaatga atgaagagca agaactgcag cgtggactga
      121 aaaatagaca tgtccaactg atttctattg gcggagcgat tggaacgggg ttgtttttag
      181 gttccggaaa gtctatccag ctagctggcc cttcgatatt gctcgcctat cttattactg
      241 gatgcatctg ttttttcatt atgcgtgcgt taggcgaact tctgttatca aacaccaata
      301 accattcttt tctggatttt gttgcagaat atcttggcaa aaaagcggct ttcatcactg
      361 gctggacgta ttggttctgc tgggtatcga ttgcaatggc cgatttaaca gccatcggaa
      421 tgtatgtacg ctactgggcg cctggtgttc ctcagtggct tcctgaactg attgcattag
      481 gtcttcttct ttgcttgaat atggtggctg tctcattgtt tggtgagtta gagttttggt
      541 ttgcattgat caaagttgta gcgatcattg cctttatcct cgtaggagct tatatgatcc
      601 tcacccacta tacgacagat attggcacag ccagtatcac gaatctatgg tctcatggcg
      661 gattctttcc aactggtgca aaaggattta tcttagcttt ccaaatggta acctttgctt
      721 ttgctgggat agaattagtt ggattagtcg ctggagaaac agaaaatcct gaaaaagtgt
      781 tgccggaagc tatcaataat attcctatca ggatcatctt attttactta ggatctcttt
      841 ttgtcattat ggcaatctat ccatggaaca gcttgaatcc agataacagt ccatttgtag
      901 aagtattttc ggaaattggg atcacgattg ctgcttcctt gatcaattta gtcgtattaa
      961 gtgcagcagc ttctgcctgc aacagtgcaa tatatagtac aggacgtatg cttcgttctt
     1021 tagcgcaaga aggcagtgcc cctaaaaaat tcaaaaagtt aacaacacat catgtgccag
     1081 ggaatgcttt gacattttct actatcgtca ttttcatttc tgttatcttg aattacgtga
     1141 tgcctagtga agtattcaca ctagtaagca gtattgccac tacttgtttc ttgtttatct
     1201 ggagtatgct tgtctacacg cacatgaaat atcgtaaaag tatcctcggc aaaaaagctc
     1261 attcatttaa aatgccgttg tacccattta gtaattatct ggtatttctt tacatggcct
     1321 ttgtgtgtgt cgtcttgttc ctaggaaaag atacgagaat cgctttatta ctaacacctg
     1381 tgtggttctt gcttctatta ctaatctatc atatgaaata tgaacgtaag aagtaagaaa
     1441 gtagttgtga cagaagtggt cagcttcgag aaataagaag gaatttacga aaattgcttc
     1501 ttaaattttt gtgaaatttc ggcttatttc ttggagataa aagcttctgt cccagcctct
     1561 tttctatttc cccggaaaca accgctgata ataggcatct gcttttttat aggaaaaaat
     1621 ccaaatacca gatacaaaaa aacgtccgaa taacccgatc aacggtacaa aaaagacacc
     1681 ggcaatcaag cataagttaa tcatcatgga gataagactt cgacggtcct ttgacaaaac
     1741 tctcacgaca tgggaatctg gtttatttgc tttcatgatt tgcctcatca agataccaaa
     1801 agaaaaactc cacatcgtgt atactaagac ataagccatc tcaggccaaa aagcttcagg
     1861 gttacgcccg acccaactag taacagaagg acataaagtc agccaaaaga gcaaaaagat
     1921 attcgaccag accactcggt aattaattcg ttctgccatc tgaaatatac gatgatggtt
     1981 cacccagatc accgcaacaa atataaagct gatggtataa gctaataatg tatttcggat
     2041 gacccataaa gaatgaaagc tagatgtatt agggatcttg atctctaata caagaactct
     2101 caaaacaatg gctaccactc catcagtaaa tgcttctaat ctcgactttg tcacgatgat
     2161 tcctcctcag atgattcagc gcttttattt tatcacttac gttattaaat aaccatcgtt
     2221 ttatataggg aattttctga aaattgttgc atatttttcg aaattttgtt acttttaaaa
     2281 aaaccgtaaa ggagttatgt atgacaaaaa aattatcatt taaagactat ctttttatag
     2341 gctccatgct tttcggtcta ttttttggtg ctggaaatct tatctttccc gttcatttgg
     2401 gtcaagaagc aggcgctgct accttttggg cgaatctagg tttcttggtt accggtatcg
     2461 gtcttccctt cttaggggtg attgccattg gtgtatcgaa aagctcaggt gtatatgaat
     2521 tagcaaaacg gataaatcaa acatatgcga tggtttttac catcttgctt tacttagtta
     2581 tcggaccgtt ttttgcttta cctcgccttg caaccacatc tttcgagatt ggtttagcac
     2641 catttatcga tcctagcaga cagacgctat atctagcaat tttcagtatt gtattttttg
     2701 tgctggcttg gtggttttca agaaaaccga caaagatatt agattatgtt ggaaagttcc
     2761 tgaatcctgc atttttggtt ttattaggtg ctttgcttct ccttgctttt ttgaatccac
     2821 taggttctgt aaatcaagcg cctattcagc caaattatca agagcatgct tttttcacag
     2881 ggtttactca aggatataac acattagatg cgcttgctgc tttagcattt gggatcatca
     2941 ttgtcacaac aatccaaaac atgggtgtaa caaaacctgc tgaaatcgct aaagacacga
     3001 tcaaatctgg tgcgatcagc attatattga tgggaatcat ttatactttg ctcgcttatt
     3061 taggtgctat gagcttaggt agctttgctc taagtgaaaa tggcgggatc acgctggctc
     3121 agattgctga tcattattta ggtacttatg gcagtatctt attagcattt atcgttatat
     3181 tagcttgctt gaagaccggt attggtttga ttacagcttt tgcagaaaca ttcacagatt
     3241 tgtttccgca aagaaattac gcattctttg ttgcacttgc tagtatcctt ccttgtttag
     3301 cggcaaacgt aggcttgacg aatatcattc aattttcgtt gcctgttttg atgttcatct
     3361 atccattagc aatgacactg attttactag tgttagttgg tcctttgttt aagcagcgta
     3421 cggctgttta tcgaatgact acttatttta cattgattgc ttcgattttt gatgggttga
     3481 acgcttgccc agaaactatc aaacaaacac ctattgttca aaatctttta tatgttgcgg
     3541 aaagctactt gccgtttttc aaattgggga tggggtggat cgtaccagca gttatcggtt
     3601 ttgttatcgg actgatttgg agtttcgcta agaaagaaga agtagcagat tgataaaaga
     3661 ggttgtgaaa gagacgttca gccttgagca ataaaaagta attttgaaaa atggcttctc
     3721 acatttttgc ataaatttga cttaataccg agaaactgac ttttgaacac cgtttattga
     3781 gaggtcgtga aaaagccgct tagtttcaag tattaagaaa tattttgtga aaatggcttc
     3841 tcacattttt gcataaattt gacttaatac cgagaaactg gcttttgaac accgtttatt
     3901 gagcgtctat aaactgacct gagtattaga gaaacaaaac ggcaaagtag ctccatatac
     3961 tttgccgttt tgttttgaac taataccgaa gagaagctga tcaaacaaca tttcttttat
     4021 aatatagatt ttagacatat atatgatata aaaatagttt tcgcaaaaaa a
//
LOCUS       DACGEU010000146         3962 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.151, whole genome shotgun sequence.
ACCESSION   DACGEU010000146 DACGEU010000000
VERSION     DACGEU010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3962)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3962)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3962
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.151"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            854..1066
                     /locus_tag="IXR40_002736"
     CDS             854..1066
                     /locus_tag="IXR40_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362522.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPAELVS"
     gene            complement(1344..3143)
                     /locus_tag="IXR40_002737"
     CDS             complement(1344..3143)
                     /locus_tag="IXR40_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HAQ4362523.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRPFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
     gene            complement(3267..3863)
                     /locus_tag="IXR40_002738"
     CDS             complement(3267..3863)
                     /locus_tag="IXR40_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HAQ4362524.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
BASE COUNT         1417 a          701 c          683 g         1161 t
ORIGIN      
        1 tatattaaat attatacaga taataacgga atattatcat cgaaacagct aacaaaattg
       61 tcataaaaaa cgagatggtt gatattagaa cttgtgtttt tgtttaggtc tagagataaa
      121 gagagacaat ttccaaatat atgtaatgaa tacaaaaaga cgtttgtcgc ggattaccgt
      181 tacaaacgtc ttttattgat tttccgagat ctcatcagtc gccatttgga atggttcact
      241 ccttatctag attcgtttaa tgctcggact gcttgttcga ttgtaatacc aaacgcaacg
      301 ttattttcgt tttgtgcatc aatcgccata aaacggttag aagttgtatc aaaagctacg
      361 cggtattgca tatttgtttt tgtaaacgtc ataaaattca tctcctttgt aatgtaattt
      421 agttcttgaa agtttccttt aaactttcga acttatacca agtttagcat cgtacgtttt
      481 ttgatgcaat taaaaagcat ttatcatttt ccttatttat tttttcttaa atggtttagc
      541 tattttcttt taatccgata agtagcccaa tcatcaaggt tacaaatact attgcttgaa
      601 tataaatcat atgctcacct ctttataaat aacttagcaa tataaagaaa aaaacgcacg
      661 aacaacatag gaatataaac aaacgttttt gtcacaacgt ctaagatcgt gttaaaaaat
      721 agttatctaa aaagcagaaa gatactcaaa ataaaaaata aaaaaatgga taaaaacgtt
      781 ttcaaataca aggtaatttg ttattataaa ataaagaaaa aacaaaataa aaataaagaa
      841 aagagggaat gaaatggtaa aagcagaagt aggaagatct tatatatgca aaccgatcgg
      901 agtatctcat gaactaatcg gctgtattga acgtacatat atcaacacgg ctgtcgtgta
      961 tgttgaaagt tatgaccaac gagactatca acttatcaat gaaagcaagt atcgcatgct
     1021 cgtaaaattc tgtgatatta gcgcacctgc tgaattggtt tcttaaacag tatttttgag
     1081 aattcgcaag aactccctta taatataaat aaagacagaa gggagcgaga agatatgcca
     1141 aaaagaaaaa gttcagggaa aatgggaatt attcttgcag tgatctctgc aattcctgct
     1201 attttagcta ttgttcgtgc gatgaaggaa tcaagagaaa gttaagcaca cattatgagc
     1261 gtcaaacaaa aaacgcatat acctgcggtg gcaggttatg cgttttttgt tgtataaaga
     1321 cttttttcat taacgatttt tgattagccg actcccaaaa caaaatttag cagtttatct
     1381 gaataagtga tttcttcatc tgtttgtttc acactttcat ttagtagtcc catctcatcg
     1441 gttatgatac catccacacc ataaaacatc atgcgactca tagcatctga atcgttgatt
     1501 gtccatacat atacttcttt tccgtcttgg tgggcagaat taatgaagtt acggttgatc
     1561 gtactatatt ccattgtcag aaaatcagca ggcgtcacag ggggcccaac aatattgaaa
     1621 ggtaagatgt agcccacata aaagtttggt tctgcttctt ttaaatctga aacggtttgg
     1681 tacgtcaaac tttgcaaaat atgatggttc tctaagataa ctttgcggta tttatggaca
     1741 aatcgttcga caaggtcatc cgaatctttt ttagaggtct tgatctcaat aagtaatttt
     1801 tggtttagct tatgtgcttt ttccaaataa gaatcaaaag aacaaacagg ggcttgcact
     1861 ccgttttcag taactgtaag atttgtcaat tctttcaatg taagatcctg tggtgttcca
     1921 tttacccctg ttaagtgacg aagatttgca tcatgcatca ctacgaaatg accatctttt
     1981 gtttcctgaa catccatctc tacataatca ggatgatagt ctctgcttgt tttttcaagt
     2041 gcttctaaag tattttgcgc cccattttgg gtactcacac ctctgtgaga gacagtcact
     2101 ggttttgtct gaacagctga agtcagataa tccatattgt aaagacagac gccaataccg
     2161 aaaaaaactg caaaaagagt caaaccagtg tttttcagcg cagagaaacg caagttgggg
     2221 gcttgtggga taaaccactt agggatctca ggcaagaagc cttcgtcatc catgaaatca
     2281 acaatgatat aaaaaatccc tacggtagac atcacgatat tgaataataa aatcccttgt
     2341 aaaagcgtca tagcaaacac agcgctgatc aatgcatagt ctgggaaaaa ttgttcaacc
     2401 atactttgtg ccaaaataac aacgatatat cctaaagaag aaaggagtaa aatcgtaccg
     2461 ccaatcacaa taaattggcc cgtgatggcc aaaagacgcg atttggtcaa tgaccagctt
     2521 tcccgaatgg ctgctcgaaa aggacgatct cgtagaatca tttccggtaa agcaaaaatc
     2581 agtcgaatcc caatatagcc aaggaaaata taaacgagta aaaaggaact gacgatgatc
     2641 caacgattag caaaaataaa atccataatg aaagcgggga tttttatttt tgacagtaga
     2701 tcagaattaa aacttaatcc gctgatcggt agaatcaata aaaaataagc aaggaaaaac
     2761 aaaaaagtaa tgggtctcac tttcttcagc tgaagtatcg tcaagtgtaa gagttgcttc
     2821 aaagagattg gttctttctt tttaataaaa aaaacactca tcaaaagaaa agtaaattcg
     2881 aaataaacta acagtaaaat cgtcatcaaa actacgatta acgagagtag aaccccagga
     2941 tgttgagaaa aaattgaagg aatattgtca taagacaaat agtcaattgc ccctcggtgt
     3001 aaaataaaac gggtcgtact gctcaataag ggtaaacaaa taaataaaat aaagccatgc
     3061 atcagcaaga catcacggaa ataagcttgt gttcctttta aaaagtccca agcattacct
     3121 aagctacgtt tcaaataatt catcctatca cctgctcttc acattgtagc gcaaatctaa
     3181 tgaaaaagga aagggtgcag tgtgttttgc agaccctttc ccagatttaa cattgtcaat
     3241 caatgactaa ttttacaaaa taaatattat ccaagaagac cacttagata ttgacctcca
     3301 taaatcaagg ccatactata taagaaaatc gacagtggtt tagcaatcaa aatgattagt
     3361 gtatatcgtt tcactgacat gtttgtcaat ccagccatca aacataacgc atcgtcagga
     3421 gcaactggaa gaaaaatagc tagagcaaac agcttctcaa aacggttttg attatccagc
     3481 cagccaatat atttgttata tgtcttatcg ctaatcatgg aaagtatgaa tggctttcca
     3541 taacgacgcc ctagcagaaa aatgataatc gaaccaatgc agattccaat atagttatag
     3601 ataaatccag cataagggcc aaatatcagg acaccagctg cagtactgat ccctccagga
     3661 atgattggaa taactacttg caggatttgg atgaagacaa aaataatcgg tcctaaaatg
     3721 atggaatcac ctactaatcc tcttaacgca ttcaaatctt tgaaaacacc taaattaata
     3781 aaataaatcg tcagcgcgat tgataggcct aatccgataa tggatatgaa atttatcagt
     3841 tttcgagagg cagcaatatt cattattcat caactcctta gaggttcttt gttaactata
     3901 ctttactaga aaagcaacta actgcgccat tttttgatat gacagaaaac aaacaatttt
     3961 gt
//
LOCUS       DACGEU010000147         3775 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.152, whole genome shotgun sequence.
ACCESSION   DACGEU010000147 DACGEU010000000
VERSION     DACGEU010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3775)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3775)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3775
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.152"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(573..1130)
                     /locus_tag="IXR40_002739"
     CDS             complement(573..1130)
                     /locus_tag="IXR40_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362525.1"
                     /translation="MRNLSNRNKILIIIVVIAVFHLGTNAVLSRIILGPKPPRPEITR
                     GEFDFRLEYEVDGERIVIEDTIVALFDGFSADAGSMAWYRTWRLHLASDRRSRNILLD
                     ELEDGRRIYYVPESANYSMGDVQKKREPNPNWYPFNGVTIEYPRNKTPEIGAKFISGL
                     EDLYDRFGIRLISWEHDPPIENRFE"
     gene            complement(1309..1920)
                     /locus_tag="IXR40_002740"
     CDS             complement(1309..1920)
                     /locus_tag="IXR40_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362526.1"
                     /translation="MNSNRGNKMEYNGSMRIVQIIFWITSGIVIIGGVFLMLPSLIFP
                     FFALISPKIPEPEITYGEFPFRIEYELDGQINIIEDTVIAEFNGCEFSAGSMKRERRW
                     RSRLASGREDLPFGDDLGIYFSRGSAQYYMGENVQSMSLKPHIALRNLEEGFKREVDF
                     ILGESGYIRTVLNFGEAQEVLTQYGITLINWEISEPIVNNFGD"
     gene            complement(2033..2290)
                     /locus_tag="IXR40_002741"
     CDS             complement(2033..2290)
                     /locus_tag="IXR40_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362527.1"
                     /translation="MRAVHVNPTIEITMIGHSKGGAEAANSVAINTNAIIFNPATVNL
                     SAYELDSNTYTANMVAYVVEGDALNVVFGGVYTYWRINHVR"
     gene            complement(2887..3165)
                     /locus_tag="IXR40_002742"
     CDS             complement(2887..3165)
                     /locus_tag="IXR40_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362528.1"
                     /translation="MEKHNITGSMYVDDQWFISTDEVKIAAIRRDYLQKIHKIKDPNG
                     KKARLIITLITSNGKKLKLAGSYDNVKKFEHWYLQKDSISLNKQFEKN"
     gene            complement(3199..3450)
                     /locus_tag="IXR40_002743"
     CDS             complement(3199..3450)
                     /locus_tag="IXR40_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362529.1"
                     /translation="MKEKPINKWSLYKNSMFGVVIFGVCAGLFLFILLQTVTLFSSNP
                     TYGWRDSIALGMFAGGYGFLLLFSILTLSPIHGLIQLWK"
BASE COUNT         1138 a          772 c          508 g         1357 t
ORIGIN      
        1 ttattccgaa taaatggtgt ccaaaagctt gcatctgcca gattatctca tttcttatga
       61 caagctaagc aaattatctc caccaaataa tttattcata tttttgactt gcgcatacta
      121 actaattctt aaattttcat acaaaatttc tcaatttccc ttaacgagta atatttatgt
      181 acggtgattc tcactagtat cccaatcact ttttaagtta tcccgatttc aattctactt
      241 caaaaatagt tgcttttatg tatgctgtta gttgattaga tggtcatttg ttgagctagg
      301 tcgtttattt taaacaagtt gtttctttag cttataccta tctcgtctac caaacgcaag
      361 atggcaaaca caaatgcata cgcatctgta tttgccactt tgattcgtat aaagctaaca
      421 actattaact cctctcagct aatagttgct ctctttttta ttcagattca tttttgctga
      481 tcacagccta gtatttcaat ggttttgaac actaaaccaa attgttccat tacaacattc
      541 actggctgat gaaatggatt agtagatttc gattattcaa agcgattttc tattggtgga
      601 tcgtgttccc aactaataag acggattcca aacctatcgt acagatcttc taaaccactt
      661 ataaattttg cacctatttc aggtgtttta ttgcgtggat attctattgt tacgccatta
      721 aatggatacc aattaggatt aggctctctt tttttctgta catctcccat agaatagtta
      781 gcactttctg ggacataata tattcttcga ccatcctcta attcatctaa taagatattt
      841 cgtgatcgtc tatcacttgc taaatgtaga cgccacgtgc gataccatgc catgctacct
      901 gcatctgcag aaaatccatc aaataatgca acaattgtat cttctatcac aatcctttcc
      961 ccatctactt catattctaa tctaaaatca aactcccctc gggtaatttc tggtcttggt
     1021 ggcttaggac ccaatattat tctacttaaa accgcattcg ttcccagatg aaacacagct
     1081 ataacaacaa taatgattaa tattttgttt ctatttgata aatttctcat tattcgcaca
     1141 tcacctctac attctcacat attagttcgt aatactcctt taatatcaaa atatctactg
     1201 gtcgtaataa tattcgctat gaattcctac tactcgtata agaaaggcca aatcatcagc
     1261 ttttacttgc tgatgatttg gcttgtttct atttatcgta attgttttct aatcaccaaa
     1321 attgttaaca atcggttcag atatttccca gttgattaag gtaattccgt attgtgtcaa
     1381 aacttcttgc gcttctccga aattaagtac agttcttatg tatccacttt ctcctaatat
     1441 aaagtctacc tctcttttaa aaccttcctc gagatttcta agggctatat gtggttttaa
     1501 tgacattgat tgtacatttt cccccatata atattgcgca cttcctcgac taaaatagat
     1561 tcctagatcg tccccaaaag gtagatcttc tctaccacta gctaatctac ttctccatct
     1621 tcgttctctt ttcatagaac ctgcgctgaa ctcacacccg ttaaactcag ctatgacagt
     1681 atcttcaatt atgttaatct gtccatctag ttcgtattca atcctaaatg gaaattctcc
     1741 ataggtgatt tccggttcgg gtattttagg tgagattaat gcaaagaaag gaaatattaa
     1801 gcttggcaac atcaaaaaaa ctcctcctat gatcacaatt cccgatgtaa tccaaaatat
     1861 aatttgtaca attctcattg atccattgta ttccatttta ttccccctat tactattcat
     1921 atccgcctat ctatatcgat cttccaatgc agagataatt gcttccatac cttgattttt
     1981 tactgagtta cctatgcgag atatcattct ccactaaggt gcatcatatt gtctatctaa
     2041 catgattaat tctccaatag gtgtatactc ctccaaaaac aacatttaat gcatctccct
     2101 cgacaacata agctaccatg tttgctgtat atgtgtttga gtctaattca taagcagata
     2161 aatttactgt cgctggatta aatataatcg cattcgtatt tatagctact gaatttgctg
     2221 cttcagcacc accttttgaa tgtccgatca ttgtgatttc aatagtagga tttacgtgga
     2281 cagccctcac cgtttaccct gaccattata gaaatcgctt acttttttga actacgcaac
     2341 aaaggataca atgctcctaa cttcactgtc tccatttttg tccactaagg aatataaaaa
     2401 ataggcatta attcatttaa ttcggtcaca acacgttacc ttttaaatca ttatactgta
     2461 tctcatacat tattatcaat aaactattat aaaaatgcaa aaaatgcttt atcaatctat
     2521 tttgtaattg gtcataatat cattgaaatc ataccctgta tcgatttttc ctatgaatct
     2581 cgtctatttg tgattgacga aaaagaggca agacagacac tggaatggta attttaccca
     2641 ctattttgct ccaactattt gtaatcgtac ccacttttga aataccgaga tgatcatttt
     2701 aattgatatg ctgattccca agcaaaaccc caagaaatta aatgctctat cgcatctagc
     2761 ttcttgggtt ttgcttatat aaattccaac atttaaattt tttatgctgt tcggtctcag
     2821 aaatgccgtt tttgcttata tcacaatatc aagatgtcaa attattcgtg ttgccgatga
     2881 ctttgattaa tttttttcaa attgtttatt aagactaatg ctgtcttttt gcagatacca
     2941 atgttcgaac tttttaacat tatcatatga tcctgcaagt tttaacttct taccattaga
     3001 tgttatcaaa gttataatta accttgcctt tttcccatta ggatctttta ttttatgaat
     3061 tttctgcagg taatctctcc taatggcagc tatttttacc tcatcagtgc tgataaacca
     3121 ttgatcatcc acatacatac tgcctgttat gttgtgtttt tccatttctt ccgagaacga
     3181 aaagtttaag gctcgttctt acttccaaag ttgaatgagt ccatggattg gacttagtgt
     3241 gagaattgag aacaacaata agaatccata tcctcccgca aacatcccta aggctatact
     3301 gtctctccat ccataagtag gattagaaga gaaaagagtc accgtttgta ataatatgaa
     3361 aaggaataat ccagcacaaa caccaaagat aacaactcca aacattgaat ttttatacaa
     3421 tgaccattta tttataggct tttctttcat tttacttccc cctactgttc tgttcacacg
     3481 gaatgaattc aaagttcata agccctcctc tttgaacata tgaatacgac ttgctaacta
     3541 tactttaaaa aagcttgttt taagcggtta taggcgagtt gtaatctcta ttcatctcat
     3601 tagcaaataa cttgccgaaa agtctactga aattaaagca gatagtggaa gaattattta
     3661 gccaggatag acactatttg tgaaacacat gtctttactt ttgaaattct atgatgaaaa
     3721 gccttggaat acagtagctc ttaattggta atactttttc cattataaat aacct
//
LOCUS       DACGEU010000148         3638 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.153, whole genome shotgun sequence.
ACCESSION   DACGEU010000148 DACGEU010000000
VERSION     DACGEU010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3638)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3638)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3638
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.153"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            <1..478
                     /locus_tag="IXR40_002744"
     CDS             <1..478
                     /locus_tag="IXR40_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HAQ4362530.1"
                     /translation="CIVMIGMTEELAKEKSFSPVRLFIKTFRQFWLKGFFYWLFAWIV
                     SVIMIFDCFFFIRFSYGKWLIPLFVLLACLSVSFSINYWYFQVRNPASKPNQVLRIAF
                     YYTLKKWYVSLLDFLLLTSLFLFFFVKPQWCILLGPSIVFGLIYFNNRKLMRTMDL"
     gene            683..2347
                     /gene="alsS"
                     /locus_tag="IXR40_002745"
     CDS             683..2347
                     /gene="alsS"
                     /locus_tag="IXR40_002745"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HAQ4362531.1"
                     /translation="MDEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVGKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAELTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            2360..3070
                     /gene="budA"
                     /locus_tag="IXR40_002746"
     CDS             2360..3070
                     /gene="budA"
                     /locus_tag="IXR40_002746"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HAQ4362532.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            3200..>3638
                     /locus_tag="IXR40_002747"
     CDS             3200..>3638
                     /locus_tag="IXR40_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HAQ4362533.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEK"
BASE COUNT         1186 a          587 c          797 g         1068 t
ORIGIN      
        1 ttgcatcgtg atgataggta tgacagaaga attagcaaaa gaaaaaagtt tttcaccagt
       61 acgtttgttc ataaagacgt ttcgccaatt ttggctaaag ggattttttt attggctatt
      121 tgcttggata gttagtgtga taatgatttt tgattgtttc ttttttatac gtttttctta
      181 tggaaaatgg ttgattccgt tgtttgtttt acttgcttgt ttatcagttt cctttagcat
      241 caactactgg tattttcagg tgagaaatcc agcgtcgaaa ccaaatcaag ttctacggat
      301 agcgttctac tatacgttga aaaaatggta tgtgagttta ctagattttt tactattgac
      361 aagtttgttt ctcttctttt tcgtaaagcc ccaatggtgt attctactag gtccttctat
      421 cgtatttggt ttgatttact tcaacaatcg taaattgatg agaactatgg atctgtagac
      481 tttataaatt gaaactttca attaagaatg acagttttta tgtaaaaact gtcattcttt
      541 ttcatttttt gaaacatatg gctaaacaaa tgaaataaaa cgtgctatac ttttgaatga
      601 aacaggttta gaaactgtat caattatttg tgattatttc taactaataa ttaaaaataa
      661 agcataaaaa ggacgatgtt caatggacga aaaaatgaaa caaggttcga aatctgtagt
      721 agaaagtttg attaatcatc atgttgatta tgtattcggt ataccaggtg caaaaatcga
      781 tggtgtattt aatgaattag aggatcaagg tcctgaatta atcgtgactc gtcacgaaca
      841 aaatgctgca tttatggcac aagcaatcgg acgtattaca ggagagccag gagtagttat
      901 cgcaacaagt ggtcctggtg ctagtaactt agctacaggt ttggtaacag cgacagcaga
      961 aggtgaccca gttttagcaa ttgccggaca agtaaaacga agcgatctat tgaagttgac
     1021 ccatcaaagc atggataatg cagcactgtt ccagccaatc acaaaataca gtgcagaaat
     1081 ccaagatcca gaaacaattt cagaagtgat tgccaatgct tatcgtatgg ctaagagttc
     1141 aaaaaaaggc gcgagcttta tcagtatccc gcaagatgta gtggatgcac ctgtccaagg
     1201 gaatgtcatc aagccattga gcgatcctaa attaggttct gcttctgcag atgatatccg
     1261 ttacctagct gaacgcatta gagaagcaaa actaccggta ctattagtag gtatgcgagg
     1321 atcaagtgaa aaagaaacgt tagccatcag gcaattagtt ggaaagacag cattgcctgt
     1381 tgtagagaca ttccaagcag ctggagtgat ctcacgtgaa ttagaagcgc atttctttgg
     1441 tcgtgtgggt ttatttagaa accaaccagg agatatgctt ttgaaacgaa gtgatctagt
     1501 tattgctatt ggctatgatc caatcgaata tgaagcaaga aactggaatg cggaaaaaga
     1561 tgcgcggatc attgtgatcg atgaagcgcc agctgaaatc gatcctttta tgcagcctga
     1621 aagagaattg atcggtgata tctcagccac tcttgattta ttgacaggtt cattagagcc
     1681 tcaacaagtg tcagaagatg caaaagaata tttagcatct cttcaagcag aattaacgga
     1741 gcgggacatt gttcaatcaa aaggagaagc aggtatcttg catcctttag aagttattaa
     1801 cacgcttcag tcaaaagtaa cagatgatat gactgttacc gtagatgtag gtagtcatta
     1861 tatttggatg gcacgccact ttagaagtta tgaacctcgt catttgttat tcagtaatgg
     1921 tatgcaaacg cttggtgttg cattgccatg ggcgatttct gctgcattgg tgcgtccaaa
     1981 tacacaaatc gtatcagttt ccggcgatgg gggattttta ttctctgccc aggatttaga
     2041 aacggcggta cgtaaaaaat tgaatatcgt tcatttgatt tggaatgatg gacactacaa
     2101 tatggtagag ttccaagaaa aaatgaaata tcagcgggcg tcaggtgtag actttggtcc
     2161 agttgatttt gtgaaatatg cagaagcttt tggcgctaaa ggaatccgag ctacaagtgt
     2221 agaggaatta gaaaaagctt tagaagaagg atttgcgaca gaaggacccg taattattga
     2281 tattccgatt gattaccgtg ataatgagaa attgggagaa acaatcttac cagatcaatt
     2341 ctattaagga agtgtcgaca tgactgaaaa aatcttatac cagcacggga cattaggagc
     2401 tttgatggct ggcttgatgg atggaacaga aacgattgct catatattag aaaaaggaac
     2461 tctgggattg ggaacattgc atgggcttga tggtgaagtc atctttttag atggcgtagc
     2521 ttatcaagga agatcagatg gctcagttgc ccaattagat ggaagtgaac ttacccccta
     2581 tgcagcaatt acagatttta cgccagatac tagtttttct gtctcaaaaa ctgcagatgg
     2641 agaacaattg aaaaaagaca tattagtaag agaagccggg gaaaacctat ttttggcagt
     2701 gaagataact ggattattca aaaatatgca catccgtatc atgccgaagc aagaaaaacc
     2761 ttacagaaga ctagcaaaaa tttcagagtc tcaaccagaa ttccaacaaa gcaatgtcca
     2821 aggaacatta gtcgggttct ttacgcctga attattccaa ggagttgctg cagcgggatt
     2881 tcacttgcat tttatcgatg atacacatac atttggcgga catgtaatgg attttgaagt
     2941 ggctgaagga aaagttgaga ttagccgcat ctcgtccctt gtacagcatt ttccagttga
     3001 tgatccgact tttgttcacg aaacgattga ttatgctgat ttagcagcag aaatccaaca
     3061 agcagaatag aaaaagacag cgagatgcgt tcaaggtgat taacctgacg tatctcgttt
     3121 ttttgaggag gaaacctagc gtttacaaaa aaactgagct ataatcttct ccatagatca
     3181 aaaaggagcg gtttttatca tgtggacaga aaaacagaaa aaagatgcat acgaaatttt
     3241 attattacag caacaaggat tattagaagc agaagataac tggttagcaa atttagcaaa
     3301 ttcatctgca ttgttgaatg agactttgcc tgagactgtc tttgcaggat attatttatt
     3361 cgatggtaat gaattgattt taggaccgtt ccaagggcga gtttcttgca cacgtatcaa
     3421 gatgggaaaa ggagtttgtg gagaatcagc tgaaaaacaa gaaacattga tcgttgatga
     3481 tgtcaaaacc catgcaaatt acatttcctg cgattcagcc gcacaatcag aaatcgtagt
     3541 gccaatggta aaagaaggta atttaatcgg tgttttagat atcgattgcg gagtaacgaa
     3601 agggtatgat gaaatcgatc aagcatttct agaaaaat
//
LOCUS       DACGEU010000149         3616 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.154, whole genome shotgun sequence.
ACCESSION   DACGEU010000149 DACGEU010000000
VERSION     DACGEU010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3616)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3616)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3616
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.154"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..250)
                     /locus_tag="IXR40_002748"
     CDS             complement(<1..250)
                     /locus_tag="IXR40_002748"
                     /inference="COORDINATES: protein motif:HMM:NF014505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAQ4362534.1"
                     /translation="MPNKNYRVYKRGTIVYVDFGVNVGYELSGNHFAIVLNNKDNSKN
                     GVVCVVPISSKKKSNYVSVGKILEVASIKQFISQADKLK"
     gene            complement(507..1526)
                     /locus_tag="IXR40_002749"
     CDS             complement(507..1526)
                     /locus_tag="IXR40_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAQ4362535.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGPNEGSSQVA
                     NNQYILLHETANETATGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGS
                     YANANSPVQIELQHTHDKATFEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHL
                     WVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSDDKPVIDPTRAGAAN
                     PTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVKADGIY
                     RPDVNQAYNTLGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYL
                     NIPQR"
     gene            complement(1537..1734)
                     /locus_tag="IXR40_002750"
     CDS             complement(1537..1734)
                     /locus_tag="IXR40_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin"
                     /protein_id="HAQ4362536.1"
                     /translation="MILPDKYYQVIKWTVLTVLPAASVLVATLGKAYGWNGTDMTVLT
                     INAVATFLGVITGVSAYNLKK"
     gene            complement(1757..2050)
                     /locus_tag="IXR40_002751"
     CDS             complement(1757..2050)
                     /locus_tag="IXR40_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362537.1"
                     /translation="MINLGEWGTIAGSITAIVSLILLVIRPVTASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHTEKLVEHTQQIKTLFRERSR"
     gene            complement(2087..2224)
                     /locus_tag="IXR40_002752"
     CDS             complement(2087..2224)
                     /locus_tag="IXR40_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HAQ4362538.1"
                     /translation="MFSFSDVKMMYDWGCFTDDQVRLFVPLCITDEEAEKIINKDKSA
                     S"
     gene            complement(2226..2672)
                     /locus_tag="IXR40_002753"
     CDS             complement(2226..2672)
                     /locus_tag="IXR40_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362539.1"
                     /translation="MKNIWKYGRTGGEYAGQVLDDMVMTVPFTDVPPLEGIRADGEPL
                     TIADQMFDPKLNQWIVLVNVLDHNDLNNLKAMYESLENENGDLKQLNAKLMLSDVAIK
                     QENTALKEKADGLAQINSKTMLASFQNSKDIAEIKEQLNPASKGGE"
     gene            complement(2675..>3616)
                     /locus_tag="IXR40_002754"
     CDS             complement(2675..>3616)
                     /locus_tag="IXR40_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362540.1"
                     /translation="PYQPNLLDDPYWLGKAPLGENIANKSVTFPIKSSAYSLYQANME
                     EEFVLGQTYTITMKATKPPIQTFIVYNEDSGDYRYGNLEPVEGLVDTWGLTFTPQKVG
                     VNYPKRLTIIQYPQSTTGACQIDWLKIEKGDTRTPNISQFKYFGEGLKDSNNPNDYSW
                     DVTPEYTEKGLNDAVNVYDPQRVEGLKNFADGIQIAGDKVISENDCTVYTLTKDNSQS
                     FIDGYATFIKHGKEVIVNGTVKFKKAYAFGVPLDDEVPDEFVAKIVHGMLTGPSGTSS
                     VSKAMYVRKDLGTIITNSEFAANEWFTFHGNYWVGEE"
BASE COUNT         1008 a          745 c          570 g         1293 t
ORIGIN      
        1 cttttaattt atcagcttgg cttataaatt gtttaatact agcaacttct aatatttttc
       61 ctacagatac ataattactt ttcttttttg aagagattgg tactacacat acaacaccat
      121 ttttcgaatt atctttatta tttaaaacaa tagcaaaatg attaccagat aactcataac
      181 ccacgttcac cccaaaatca acatatacaa tagttcctct tttataaacc ctataatttt
      241 tattaggcat gcatctttct ttattaagat aaaaactttt actttgtaac cagttgtgta
      301 agtatttata cttaggatat ccagataaag cttctccaat aaacctaaca tttgcttggt
      361 tacatgctgc ttctatttcc tcttttttaa ctataattaa gcacctcttc tcactaacta
      421 ttaaattacc gcatttttac aagataatca ataagttatg gacaaatttg cattatgtac
      481 ttcccctcaa aaacgagggg ctatttttat cgttgcggaa tatttaaata ccagcgttta
      541 tcatgaaaat cttgtgctcc gcctttagtg ttcccttctg gatcattcgt tgcccgcatc
      601 attacataga ctttcttatt agggaagttg cgcatgttaa aagatacatg atagccaaca
      661 tttcctaaag tattataagc ttgatttaca tctggtctat atattccatc agcttttact
      721 cgagctaatt ctttcccagt attgtaatcc ataatgaaga tatactcgta tttatagtta
      781 gcgatgtgcc aaccagccac atgtaagttt gcgttttcga tttctccgaa ctgatcaatg
      841 tgggcgtaat ttgttccatc tgtcagggta ggatttgcag cacctgctcg agttggatca
      901 atgactggtt tatcatctga agttgtcgga ttttcatcgg taaatccatg agccaaatca
      961 taggctaatt tttctttact tacgcccatt tcagaaagat aaccgtaagg atctgtatga
     1021 tcgccccaaa tattttgtgt tacccataaa tgcgatttga tccctggttg attatacggt
     1081 gtgtctagtg taagtggaat accatatttc attgctgaat ctctagctaa ttcaacgtat
     1141 gccttgtagt ttttctcaaa cgttgcttta tcatgtgtgt gttgtaactc aatctgcaca
     1201 ggactatttg cattagcata cgaaccagca ccgtactgta cataaccagg ttgaccgact
     1261 tgataaacaa ttccgccgtc tcccacaata taagcagtat aagcgctagt ccatgaacgt
     1321 tgcatatact gcgcttcatt gcgtcctgtt gctgtttcat tagccgtttc atgcagtaaa
     1381 atgtactgat tatttgctac ttgtgagcta ccttcgtttg ggcctaaatt aaattcattg
     1441 ttaatcgtat aggcaaaccc attaattggc aataaaaaaa gagccgttaa taggctcatc
     1501 gcagtaatag taattttctt tttcatttgt ttcctcctat tttttcaaat tataagccga
     1561 cacgccagtg ataacgccta aaaatgttgc tactgcattg atagtgagta ctgtcatatc
     1621 tgttccattc catccatacg ctttgcctag tgttgcaact aatacagatg cagctggcaa
     1681 tactgttaaa actgtccatt taatgacttg ataatactta tcgggtaaaa tcatttcttc
     1741 ttaactcctt tcttttttac cgagatcttt ctctaaataa agttttgatt tgttgtgtgt
     1801 gttctaccaa tttttctgta tgtgtatcta atctttcatc gtgtttcttt agttcttcat
     1861 gaatcatcaa tcgatctgat ttgctcgatt ctaaatcttt agtcagcaaa tctaaattgt
     1921 gacttacttt tgaaagagtt tcagtaatct tcgagaaaga tgcagtgact ggtcttatta
     1981 ctaataaaat caaagaaaca atcgcagtga ttgatcctgc gattgttccc cattctccta
     2041 aattaatcat gtgacaactc ctttacctta aataaaaacg catcacttaa gatgcgctct
     2101 tatctttatt aatgattttt tctgcttctt cgtctgtaat gcatagtgga acgaatagtc
     2161 gaacttgatc gtcagtaaaa cagccccaat catacatcat tttcacatcg ctaaaactaa
     2221 acatactact cacctccctt tgaagctgga tttagttgct ctttaatttc tgcaatgtct
     2281 ttgctatttt ggaacgaagc aagcatcgtt tttgaattga tttgtgctaa accatccgct
     2341 ttttctttca atgcagtatt ttcctgttta atcgctacat cgcttagcat gagtttggcg
     2401 ttgagctgtt ttaaatcgcc gttctcattt tctaacgact catacatcgc tttgagattg
     2461 tttaaatcgt tgtgatctag tacattcact aaaacaatcc attggttcag tttaggatca
     2521 aacatctgat cagcaatcgt tagtggttcc ccatcagcac gaattccttc gagtggtgga
     2581 acatcggtaa atggaacagt cataaccata tcatcaagca cttgtccagc atactctcca
     2641 cctgttcgtc cgtatttcca aatatttttc atttttattc ctcccctacc caataattac
     2701 catggaatgt aaaccattca tttgcagcaa attcgctatt cgtaataatt gttcctaagt
     2761 cttttcgcac gtacatcgct tttgatacac tacttgttcc tgacggacct gtaagcatgc
     2821 catgaacaat ttttgcgaca aattcatctg ggacttcatc atcaagtggt acaccaaaag
     2881 cataagcttt tttgaacttt actgtaccat ttacaataac ttcttttccg tgtttaataa
     2941 atgttgcata cccatcgata aacgattgac tgttgtcttt agttaatgta taaacagtgc
     3001 aatcattttc actgatcact ttatctcctg ctatttgaat accatcggca aagtttttca
     3061 aaccttcaac tctctgagga tcatacacat taacagcatc attcaagcct ttttcagtat
     3121 attcaggtgt gacatcccaa ctgtaatcat tgggattgtt actgtctttc aagccttcac
     3181 caaagtattt aaactgacta atattcgggg ttcgtgtgtc gcctttttcg atcttgagcc
     3241 agtcaatttg acatgcacct gttgttgatt ggggatactg gataatagtt aaccgtttgg
     3301 ggtagttaac tccaaccttc tgcggtgtaa aagtcagacc ccatgtatca actaaccctt
     3361 ctactggctc taagttacca tatctataat ctccactatc ctcgttgtaa acaatgaacg
     3421 tttggatagg tggtttggtt gccttcatgg taattgtata ggtttgacct aaaacaaatt
     3481 cttcttccat gttagcttgg tataggctgt aggcgctaga tttgattgga aacgtaacag
     3541 acttattagc aatattctca cccaaaggcg ctttacctag ccagtaaggg tcatcaagta
     3601 agtttggctg atatgg
//
LOCUS       DACGEU010000150         3517 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.155, whole genome shotgun sequence.
ACCESSION   DACGEU010000150 DACGEU010000000
VERSION     DACGEU010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3517)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3517)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3517
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.155"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            81..353
                     /locus_tag="IXR40_002755"
     CDS             81..353
                     /locus_tag="IXR40_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362541.1"
                     /translation="MNLIATYYRTLEELKKQNAKWFFQALLCLEVGVKPSTIKPSEYQ
                     ALELTYGKFVETKKAKTVSSEWLDYFENINKYGAYYTMKKEDNENE"
     gene            346..1053
                     /locus_tag="IXR40_002756"
     CDS             346..1053
                     /locus_tag="IXR40_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362542.1"
                     /translation="MNKVIYQLTTEDVSHFLTNKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYLESETSQTKVTVSNNYLDVYKHRPETVKKGTELLRLETEKYIMNVYLERS
                     ELVENFVSCTICRKHYYSESEYYSIFESMELMEEEMEELNSKNATIDDYYLVFTRFLT
                     CGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNE
                     LDRKRMPYQRFERKKRQ"
     gene            1433..1612
                     /locus_tag="IXR40_002757"
     CDS             1433..1612
                     /locus_tag="IXR40_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362543.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESKIMCIALDLL
                     IAQEKVGFDIPALKK"
     gene            1937..2200
                     /locus_tag="IXR40_002758"
     CDS             1937..2200
                     /locus_tag="IXR40_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PbsX family transcriptional regulator"
                     /protein_id="HAQ4362544.1"
                     /translation="MEMLPIKKWGNSNGLRLPKYIMEYLGIHTEDKVKIIQEEVNGQK
                     RLIIEAANIENELTIEQLFENYTDERNHVTIQNLGEAVGNEKW"
     gene            2194..2544
                     /locus_tag="IXR40_002759"
     CDS             2194..2544
                     /locus_tag="IXR40_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAQ4362545.1"
                     /translation="MVRKPRQGDILLLNTAPRSGHEQTGKRPYIVLSHDIIADYSNVV
                     TVAPISSTTRNYPLYVNINSEYEMKTTGKVLLDQLTTIDYEARECIFLEKAHDSLVEE
                     LLMKVRTVFQKVSK"
     gene            complement(2568..3182)
                     /locus_tag="IXR40_002760"
     CDS             complement(2568..3182)
                     /locus_tag="IXR40_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAQ4362546.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDFVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANAKDPQ
                     RRLVYKNIVEDLKKGVAIAKIAKDYNVTRQTVYRIKKDSMVNHE"
BASE COUNT         1245 a          535 c          663 g         1074 t
ORIGIN      
        1 atgagacacg tgttccaaaa aaacattata aggaaagatt gtcggtagct gtggaagaaa
       61 tgattgaatc aggtgtcgaa atgaatctca ttgcgacgta ctatcgaaca ctggaagaac
      121 tgaaaaaaca aaatgcaaaa tggtttttcc aagccttact atgcttggaa gtaggtgtca
      181 aaccaagcac tattaaacct tctgaatatc aagctttaga actaacgtat gggaaatttg
      241 tcgaaacgaa aaaagccaag actgtttcaa gtgaatggtt agattatttt gaaaatatca
      301 ataagtatgg cgcctattac accatgaaaa aggaggacaa cgaaaatgaa taaggtgatt
      361 tatcaactaa caacggaaga tgtgtcacac tttttaacaa acaaagaaca tttgaatgaa
      421 gtaatcagac ggattcaaaa agactttagt tgtatggaag aaatgaagta ctttattcaa
      481 agagtcgaag aacaattgta tttggaaagt gaaacgagtc aaacgaaggt cacagtcagc
      541 aataattatt tagacgtgta taaacatcgt cctgaaacgg taaaaaaagg aacggagctt
      601 ctacgactag aaacagaaaa atacatcatg aatgtttacc tagaaaggag tgaactggtc
      661 gaaaactttg tcagctgcac gatttgcagg aaacactatt actcagaatc agaatattat
      721 tcaatttttg agagcatgga attaatggaa gaagaaatgg aagagctaaa cagcaaaaat
      781 gcgacgatag acgattatta tcttgtattt actagatttt tgacgtgtgg aacggaatct
      841 atcgtgttaa tgggaatgga ttatgaactc gctgtacccg aagcattttt gagggaatat
      901 gtagaagaag tagataaccc aggcgacgac tggtacacga ctttaactga ttttttagat
      961 acctacactt acgacgatac agaagaaatc caaaatgaac ttgaccgtaa acgaatgcca
     1021 tatcaacgat ttgaaaggaa aaaaaggcaa taatcattta taccgaaaag tgagaatgtg
     1081 tgaaataaga acaaaaacct tgaaattaag ggaatggttc ttatttcgca ccaatcgctc
     1141 caaccgcccc cgccgcttag gtggtgcgaa ataagcgggc aaagcccgat aacctaagag
     1201 aaagaaggag atccatatga ataaaatcat tcctctgttg ttcgtactgt gtattggcga
     1261 gatacttatg cgtcatggtg cagctgtaca tttaaacttc gtagtattct taggaatact
     1321 agtattttgt ttgatttttt ggcgctttgt gttagccctt gtgagtctac tattcaagtt
     1381 gattgcagcc atatttttca tagggttatt tcgatgaaag gagagagtac taatgccaat
     1441 tgcaatagga aataaacggt tacccgtgac attagatgaa aagagacaaa aagaattgca
     1501 gcaactaaag cagaagtacg gaaaaagtga atctaagatt atgtgtattg cgttagatct
     1561 attgatcgcg caagaaaaag taggatttga tataccagca ctaaaaaagt gacgtcactt
     1621 ttcatttgaa gaaacaaaag tgatagcact taattgttcc tactatttag aatattttct
     1681 atgtcctttt tattccattt tgtatcaata actatgaaat ctttaaagta tccagatcaa
     1741 tttttttctt acctgattct aaagattttg ttttcttaaa catattatga tttcctttcg
     1801 actattttca tataaatgtt aacatagttt atggattcat ggaatgttaa tctaatttaa
     1861 tagaaaagga taattaagta tatacgtttt ttcttatgta tgttatacta tgtatataca
     1921 gaaagaggtg tctactatgg aaatgttacc tataaaaaaa tggggaaata gtaatggcct
     1981 tagattgcca aagtatatta tggaatatct tggaattcat acagaagaca aagtgaagat
     2041 aatacaagaa gaagtaaacg gtcagaagcg gctaattatc gaagcggcta atatagaaaa
     2101 tgaattaaca attgaacagt tatttgaaaa ttacactgat gaaagaaatc atgtgacgat
     2161 tcaaaattta ggtgaagcag taggtaatga aaaatggtga gaaaacctag acaaggcgat
     2221 attctattat tgaatacagc acctcgatct ggacacgaac agacaggtaa aagaccttat
     2281 attgttttaa gtcatgatat tattgcggat tatagtaacg ttgttacagt tgctccaatt
     2341 tctagtacaa ctagaaacta tccgctatat gtaaatataa actcagaata tgaaatgaag
     2401 acaacaggaa aagtattatt agatcaacta acgacaattg attatgaagc cagagagtgt
     2461 atttttttgg aaaaagcgca tgatagttta gttgaggagt tattgatgaa agttagaaca
     2521 gtttttcaaa aagtaagcaa ataaaataga aacagcagca tgatcaacta ttcgtgattg
     2581 accatgctgt ctttttttat tctatatacg gtttgtctcg taacattgta gtcttttgca
     2641 atcttagcga tcgcaacacc tttttttaga tcctcaacga tgtttttata aacaagacga
     2701 cgttggggat cttttgcatt ggcactgtat agcttaggac gtcctttata aacaccgttc
     2761 gcttttgcaa tcttaatgcc ttgtgcctga cgtcgtttag attcggtacg ttcttgttca
     2821 gcgatcatgg ccaaaatttg aatgatcaaa tctttaatga atttatccag gagaggattg
     2881 ccaattgctt cggccatgat cggtagactt gtgatgatca gctgcacatt tttcttcttc
     2941 aagtaattga ctgaagcgat gatctcgtcg taatttcttc caagtcgatc aatagcttcc
     3001 acaataaaaa tatcttgatc tcggacgaaa tccagtgctt cttgaaaaac aggtcgatga
     3061 gtaatcgttg cgccagattg tttctcaatg aaaattctct ctgcaccgaa ttttttcatt
     3121 tcttcaatct gccgttgttc attttgatcg atggatgaga cacgtatgta tgcaactctc
     3181 aaaattttta cctactttct gcaactattt aaaaaacacc ctaatcatac acgagaaaac
     3241 cagatttttc aatgtcgcgg tcgtgtctag ttagggtata ccttatatag acaaaaacta
     3301 atgatggagg aaatagtatg tgtcactttt ctttttaaat ggcaaaaatt tttaataata
     3361 tatgacaatt tagaaatcaa ctataagact gattaattca aaatgatctt agaatcattg
     3421 tatgaacact aaatactata ttgttttcta ttaatcgtta tataaacgat tatgaattca
     3481 aagctacttt ttatgacgtc aatcagagag tgtaaaa
//
LOCUS       DACGEU010000151         3454 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.156, whole genome shotgun sequence.
ACCESSION   DACGEU010000151 DACGEU010000000
VERSION     DACGEU010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3454)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3454)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3454
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.156"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            <1..950
                     /locus_tag="IXR40_002761"
     CDS             <1..950
                     /locus_tag="IXR40_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4362547.1"
                     /translation="DEFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIEENDKNSIIV
                     HEEFAKQNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSEN
                     MVFVDYSTSQEILNNSENNEIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDS
                     NAFEESLESVSGIKYIIKVMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKI
                     QIIMQFIFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMSN
                     ITTLGQSYLILISIIVLSVVFASSLMLIKKPKEILSKIS"
     gene            960..1616
                     /locus_tag="IXR40_002762"
     CDS             960..1616
                     /locus_tag="IXR40_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAQ4362548.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            1616..2992
                     /locus_tag="IXR40_002763"
     CDS             1616..2992
                     /locus_tag="IXR40_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4362549.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGGVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            3122..>3454
                     /locus_tag="IXR40_002764"
     CDS             3122..>3454
                     /locus_tag="IXR40_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAQ4362550.1"
                     /translation="MARKKRNPDAEKLAESILNTYQPESVEDMQDVLKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKKHDNRRNGYGNKTLKTSFGKVNIDVPRDREASFEPELIP
                     NRKRDVSDI"
BASE COUNT         1370 a          387 c          605 g         1092 t
ORIGIN      
        1 ctgacgaatt taagaatgtt gtttcactcg aagctacaaa taatactaaa agaaatattt
       61 tatttagtag tggagtattt acaattaaag aaggtaaaaa tatagaagaa aatgataaga
      121 attcaattat tgttcatgaa gaatttgcta aacaaaacaa tctaaaatta ggtgatgaag
      181 ttgatcttga attactagat attgaaaaaa gtggaaaaat aaaaagtcat aaatttaaaa
      241 ttatagggat cttttctggt aaaaaacagg aaacatatac aggattatct tctgatttta
      301 gtgaaaatat ggtgtttgta gattattcaa caagccaaga gatattaaac aattcagaaa
      361 ataatgaaat tgcaaataaa attttaatgt attctggtag tgcagaatct acagacttag
      421 ccttaaacaa attgaaagag cttaaaattg atgagtcaaa gtattttgtt gaaaaagatt
      481 ctaatgcgtt tgaagagtct ttagagtcag tgagtggaat aaaatatata ataaaagtaa
      541 tgacttattc tattatgttg ggtgggatgg ttgttctttc attaatcttg attctatggt
      601 taagggaaag aatttatgaa ataggtatat tcttatctat tggaacatct aagatacaaa
      661 ttataatgca atttatattc gagttaatat tcatatcgat accaagtata atatcttcct
      721 tatttttagg aaatgtatta ctaaaagtaa ttgtagatgg attcattaac tcagaggatt
      781 caatgatttc cggtggaagt ttaataaata atagtagttt tatgtcaaat ataacaacac
      841 ttggacaaag ttatttaata ttaataagta ttattgtttt atcagttgta tttgcttctt
      901 cattaatgtt aatcaagaag cctaaagaaa tcttatcaaa aataagttag gagaaaataa
      961 tggatatatt agaaataaag aatgtagcat atagttatgc aaattctaaa gaaaaagttt
     1021 tgtcaggagt aaatcaaaaa tttgaacttg ggaagtttta tgcgatagta ggaaagtcag
     1081 gaacaggaaa atctacactt ctttccttac ttgctggact tgataaacct caaacaggaa
     1141 aaatattgtt taagaatgaa gatatacaaa ataaaggata tagtaatcat agaaaaaata
     1201 atatatcttt agtatttcaa aactataatt taatagatta tttatcacca attgaaaata
     1261 ttagattagt aaataaatca gcagatgaaa gtatcttgtt tgaactaggt ttagataaaa
     1321 aacaaataaa aagaaatgtt atgaaattat ctggtggaca gcaacaaaga gtagctattg
     1381 ctagagcatt ggtatcagat gctccaataa tactagctga tgagcctact ggtaatctag
     1441 acagtgttac tgctggagaa ataattaata tattaaagac attagctaaa gatagaaata
     1501 aatgtgtaat agttgtaaca catagtaagg aagtagcaga ttctgcggat atcattttag
     1561 aactaagtgg taaaaagttg aaaaaagtaa ataaaatgaa tttggaggtt gaataatgat
     1621 aaaaaatgca tttgcttatg taactagaaa aagtttaaaa tcattaatta tcatattagt
     1681 tattttatct atgtcaactt taagtctcat tagtttatct attaaagatg ctacggacag
     1741 agcttcaaaa gaaacatttg ctaatataac aaatagtttt tctatggaga taaatagaca
     1801 agtaaatcca ggaacaccta gaggtggggg aaatgtaaaa ggtgaagata ttaaaaagat
     1861 atctcaaaca gatagtatag actcctatgt aaaaagaata aacagtgttg cagatttagt
     1921 tgattatgat attattgaaa ctcaagagac tcttgcgaat caatcacctg aaagagcaaa
     1981 gaattttaaa agaacagtta tgttaactgg ggttaacgac tcaacaaaag aaacaaaatt
     2041 tgtatcagaa gcatataaat tagtagaagg aaagcattta gaaaatgaag ataaaaataa
     2101 aatcttaatg cataaagatt tagctgaaaa aaataacctt aaagttggag ataagataaa
     2161 aataaaatct aatttatttg atgctgataa tgagaaaggt gcagatgaaa cagtagaagt
     2221 agaaattaaa ggtctattcg atgggcataa tagcggtgga gtaagtgcag cacaagaact
     2281 atacgaaaat acattaatca ctgatattca tacagctgct aaagtttatg gtaataccga
     2341 agatacagct gtataccaag atgcaacatt ctttgtaaaa ggtgataaga atcttgatag
     2401 tgtaataaaa gatcttggga aattagatat aaattggaga gaatataatt tgattaaaag
     2461 ttcatcaaat taccctgcat tacaacaatc tatatcaggt atttactcaa tttcaaataa
     2521 attatttttt ggctcattaa tatttgcagg agttgtagtt tcattattat tattcttatg
     2581 gatgaatgct agaaagaaag aaatagcagt attactatca ttaggtatat caaaattaga
     2641 aatttttggt caattcctaa ttgagatggt atttatatca atccccgcat tcgttggttc
     2701 ctatttctta gctcaatata cagctgacaa gcttgggaat aatatattga ataaggttac
     2761 tggtgatata gctaaacaaa tagctaaaca atctgcatct agccaattag gtggtggggc
     2821 agaagctgaa ggatttaaca agacattatc aagtttagat atcaatgtat tacctaaatt
     2881 catgatttat gtagttatat ttatgagttt agtacttctt gtatcattga ttatttcttc
     2941 attcaatata ttaagaagga atccaaaaga attattaatt gacaataatt aaaattttcg
     3001 gtgcttttta gcaccaaaaa tgagagtgta atataaaccg tgtaagtaac catcaatcct
     3061 aggcgggtgg ttgcttcacg gtttttattt ttctaaaata agatcaagag gtgattacac
     3121 gatggctaga aagaaaagaa atcctgatgc tgagaagtta gctgaatcca ttttgaatac
     3181 ttatcaaccc gaatctgtag aggatatgca agatgtttta aaagatgtgt ttggtccctt
     3241 atttgaaaaa atgcttcaag gagaattgaa taaccattta gggtatgacg cccattctaa
     3301 agagccaaag aaacatgaca atcgacgaaa cggttatggc aataagacgc ttaaaacgag
     3361 ctttggtaaa gtaaacattg atgttcccag agaccgggag gcttcttttg aacctgagtt
     3421 gattcctaat agaaaacgag atgtctccga catc
//
LOCUS       DACGEU010000152         3308 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.158, whole genome shotgun sequence.
ACCESSION   DACGEU010000152 DACGEU010000000
VERSION     DACGEU010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3308)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3308)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3308
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.158"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            191..1714
                     /locus_tag="IXR40_002765"
     CDS             191..1714
                     /locus_tag="IXR40_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HAQ4362551.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            1951..3291
                     /locus_tag="IXR40_002766"
     CDS             1951..3291
                     /locus_tag="IXR40_002766"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HAQ4362552.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
BASE COUNT         1056 a          543 c          724 g          985 t
ORIGIN      
        1 aggaaacgct acaatgaaaa agaagaaagc tttaaaaacc tgaaaaaaga ggagggaata
       61 gggaaaaacg aactttttga acaaaagttt tacaaaatgc gtgttattat ttttgttctg
      121 atactctttt tgataaaata acattagagc caaaattgtt gtctctaacg gaaaagaaag
      181 gaagaagaag atggaacaaa caaaaaagaa aaaatttcaa atgccttcag cgtatacggt
      241 cttatttatt attattgcag taatcgctgt acttacttgg tttataccag ctgggcacta
      301 tagtgtagac gatgcaggca acatcgtcgc tggatcatat gaacgagtac aacaaaatcc
      361 tcaagggctg tgggatattt tcatggcgcc aatcaatggg atgctaggtg taccagcggg
      421 ggagctaact aaagaaacac ctgctgcaat cccaatctct ttcttcattt tggttgttgg
      481 tggattttta ggtattatca acaaaacagg ggcactagat gccgggattg cttcagttgt
      541 gaagaaattc aaaggaaaag aaaaaatgct tattccagta ttgatgctgt tatttgcatt
      601 aggcggctct acttacggaa tggcagaaga aacgattcca ttctatgctt tactgatccc
      661 agtcatgatg gctgtaggct ttgatacagt agtagctgta gcaatcgtat tagtagggtc
      721 tcaagtaggc tgtctagctt caacggtaaa tccttttgca acaggcgtag cttcacaagc
      781 tgttgggatt tcgatgggtg aaggtattgg tcttcgattc ttgatgttcg ttattttgtt
      841 agctatttct attgtatatg tgtatcgtta tgcatcaaag atcgaaaaag atccaacaaa
      901 atcattagta tacaaccaac gtaaagaaga tatgaagcat ttcgatattg aagcaatcgg
      961 tcgtcaagaa gtaatcacga aaaaacaaaa acatgttaat gtattgttct ttattacttt
     1021 tggtatcatg atcatcagtt tgattccttg gacaaccttg aatgcgaatt tcacgatttt
     1081 tgaatcattg acaaactggt taacaaacct tccggtacta ggtacggttc taggtaaaag
     1141 catgcttcca ttaggtgact ggtacttccc agaaattact atgttattct tagtaatgtc
     1201 catcgtagta gcaatcactt atggcatgaa agagtctgaa tttgtctctg aatttttagc
     1261 tggtgcttct gatttgatcg gtgtagcaat cgtagtagct gttgctcgtg gtatccaagt
     1321 ggttatgaac aatggattaa tcacagacac catcttacat tggggcgaac aaggattaag
     1381 ttcattatct tcaagtgtat tcatcattat tacatttatt ttctatatcc ctatgtcatt
     1441 cttgattcct tcaacttccg gcttagctgc tgcaacaatg ggaatcatgg gacctatggg
     1501 tgaatttgcc ggcgtcggta aggatttagt aatcactgct tatcaatctg catctggttt
     1561 agtaaactta attacaccaa catctgctat cgtaatgggt gctgtagcaa ttgctcgttt
     1621 cgatgtttca gtgtggtgga aatttaccgg taaattaatt gcgatattat ttgtagccat
     1681 ctgtgtgatc ctaggtgtag cagcaatgtt ctaaacctag acaaatacag gtacaaggtc
     1741 tatcataaga atgaagaaac cgataaacgg ctatcgataa gcacgtggat aagtcaatag
     1801 ctccattcag tgagtgtttt ttctttcatc atttgttaag aacattctgc ttgctgatgg
     1861 agcaggctta aaacgtcatt atttgagaag aagaggttgt gtcggaggaa tttgacatga
     1921 ccctttttaa catattagga ggataatatc atgaaaaaat ttgtgacaga acaacatcat
     1981 gaacaagcat tagaatcatt gagcgaattg atccgaattc cttccgtact agatgaagca
     2041 gattcaggac aaggacatcc cttcggtaaa aaagtgattg aagctttgga taaagtattg
     2101 gaaatcagtg aaaagctagg atttagaaca tttaaagatc cagaaggcta ttacggttat
     2161 tcagagattg gctctggaga tgaattattc ggtatcttgt gtcatatgga cgttgttcca
     2221 gcaggggacg aaaataattg ggaaacaaaa ccattcgatc caactataaa agacggctgg
     2281 ttagttggtc gcggatccca agatgacaaa ggtccttcta ttgcggcaat gtatgccgtc
     2341 aaagctttga ttgatgctgg cgtggaattc aagacacgta ttcgttttat ctttggtaca
     2401 gatgaagaaa atttatggcg ttgtttagaa aaatataacg aaaaagaaga aggaattacg
     2461 caaggatttg cgccagatgc tgaatttcct ttaatttatg cagaaaaagg cttattgcaa
     2521 gcttacttga caggaccagg aacgaacgag ttttctgtaa aagctggagg agcgttgaat
     2581 gttgttcctg atgcagctcc ttactctgga gaaaagcttt ctgaagtaaa agaagcattg
     2641 aaaaaacacg aattcgattt cgaagaacaa ggtgaaggca tcgtcgttct tggtaaaagt
     2701 atccacgcga aagatgcagc acaaggagtg aatgctattt ctcgtctggc aattgctctt
     2761 tcagaagtat ttgattttgg cccaatcaat ttcttaggaa aattagttca agaaaatgca
     2821 actggtgaag ctgtcgtggg caaaacagaa gatgaacaat ccggcgagct aacgatgaac
     2881 tttgcaagtt tggaaatcac accagaacaa acaaaaatcg gtgtagatat gagaatccct
     2941 gttacattca agaaagatga tttagtagct aaattaacta aaacagcaga aaaatatggg
     3001 ttgacttatg aagaatttga cttccttgat tcattatacg tgccactaga cagtgagtta
     3061 gtgaaaaatc tattggggac atatcgcgat attactggag acatgactga accgtttgta
     3121 tcaggcggcg ctacttttgc tcgtacgatg aaccagtgtg tggcattcgg tgcgatgttc
     3181 cctgatactc ctgactttat gcaccaggcg aatgaacgat gggaattaag tagtatgtat
     3241 aaagcaatgg aaatttatgc agaagctgtg tatcgtttat gtgctaaata aaaataaaca
     3301 tacaaaaa
//
LOCUS       DACGEU010000153         3301 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.159, whole genome shotgun sequence.
ACCESSION   DACGEU010000153 DACGEU010000000
VERSION     DACGEU010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3301)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3301)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3301
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.159"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(553..2166)
                     /locus_tag="IXR40_002767"
     CDS             complement(553..2166)
                     /locus_tag="IXR40_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-disulfide reductase"
                     /protein_id="HAQ4362553.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
     gene            complement(2307..3215)
                     /locus_tag="IXR40_002768"
     CDS             complement(2307..3215)
                     /locus_tag="IXR40_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4362554.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
BASE COUNT         1075 a          564 c          578 g         1084 t
ORIGIN      
        1 gttaaataaa taggaacaaa aaaattaaat tatttaatac acacattagg gatcattcat
       61 tgaaggatta gaagacaacg aggatggcga aaaatatgat tacaatagaa aagtcgttct
      121 aaaccaatca gttcctagta tcacacaacg caagccagtc gatttggtga gattagagga
      181 gtgaaagcaa actttattat ataagaaaaa atattcgaaa gggatgctag tttaggtact
      241 agtgctgata gattaatatg atgcctcgta atattaggcg tagttactct agagacatca
      301 ctatggacta tgatttgtct cagagtcaca acatgttttt ttatgaaaag aaacagctaa
      361 aataattaaa ttgcgcaatg tttaaacttt cttaaactat aacctaataa atgtgaagaa
      421 ataatgcaca atttcttcac atttatcttc tattctatat acataccaac caacaaccct
      481 atatactttt tcatttttac tcctcaagta aaaataactc ctagaccgcg gctacccacc
      541 gcggtcgttt ttttattctt caatcaaaat cgctttgata cccaaacctg ccaagattcg
      601 ggcagaagta taagtattca atcctcttct gaaagtaatg taaacttttt tatcttttgg
      661 gatttcattg attcgatctc gtaactcatt cattggaata ttttttgttg ccgagatact
      721 gccagaaggt gctttattag gttcacgtat atctaaaaag aacgcttctt tcaaatcgtt
      781 ttcgggtata tcacttgctt tgatcgtttc tacgatattc gtcatttgat tgattgcgac
      841 ataaccagct atattcaacg ggtcacgggt agtagaatac ggtggagagt aaggcaactc
      901 caaatcaggc aaatcaaaga ctgtcaagtt tccggtgatt gctacagaaa gttctcccat
      961 ccgtttatcg acaccttttt ctccaaatgc ttgtccacct aaaatacgac cgctatctgc
     1021 atcaaaaatc agctttagat ttaatcttgt agcttctgga tagaaatagg catggtcaaa
     1081 gggagtgata aaaacagttt tataatttgt tatgcctgat gcttttaatt catgttctgt
     1141 cattcccgca taacttgctg tatgatcaaa gatttttgcg acacctgcac caatatatcc
     1201 gcgatagcgc ataggcgtac catttaaaat atctgccagc atatgtcctt gacgattggc
     1261 cgcactggaa agcatacttt ggatcggctg accagtcact acactagtcg tttcgataat
     1321 atcgccaatc gcatagatgt ccggcagatt ggtttgtaac tggtcatcaa caatgatctg
     1381 acctgtatct gataattgta tgccggttgc tttcaccact tcattcttcg gagaaacacc
     1441 aacagcaaaa attagcatat cagcagaaag gacggagcca tctgataata ctatttctcg
     1501 acctttatca cggatctcag taactcttgt ttctaaatga acggctaatc cttctttcag
     1561 caatttgtca taaactaaat tagcaatttc tggatcataa gggaaagcga cttgtggcaa
     1621 ttgatcgatt aaagtcacgt ctaagccgcg atgcttgaaa ttctcagcta attccagacc
     1681 cataacacct gcaccaagaa tgacgacatg ttgtggattt ttttcttcaa ggaacgattt
     1741 gattcgatcc gcatccgtca cactacggag gacaaagccg ttttctgctt caaaaactcc
     1801 gggaatatcc ggataatctg gtctagcacc agaagagatg atcaacttat cgtaatctgt
     1861 ttttatttct tcatttgtgg ataggtcttt aactgttaat cgcttagtag aaggatcgat
     1921 tgctgttact tcgtgtttag taaagacatc gatgttgttt tttgttttca atatttctgg
     1981 tgtacgttcg atcagcgagt cacggtcagt gatcacacct cctaaataat aaggcaaagc
     2041 acaacttgca taagaaatat tttctccgcg ttcatagata atgatttcgt gcgcttcatt
     2101 caatcgacgg aaacgagtgg caaatgaagg accgccagct acaccgccaa tgacaacaac
     2161 tttcataaaa acatctcctt ttctacgttg atcgtactat gttatggtaa aaaacagcaa
     2221 ataattgtgc cggaaaatta ttgtttattt tgaatagaca gaaaatatag agaaataatt
     2281 tgtggataaa acctaaaaat ttttttctat tttaaggata gataatactt tgaaggggat
     2341 aaccctgtat attttttaaa agctgaagaa aaatgatgga tcgaatgaaa tcctaatata
     2401 tctgcaattt ctgtataggt taattcattt tctagcacga gacgttttgc tttttccatt
     2461 tttagttctt taaaatagct aataacactt tttccattca cttttctaaa atgttttttt
     2521 aagctggctg gactgataaa aaaaatttgg gctaattgtt caagcaaaaa attttctgaa
     2581 agatgttctt ctaaatatcg tatgattgga tcaactaatt catctgaata aagaatatgc
     2641 ttttttttag gaatgacttt ctcatttgaa ggtattgtca ataaagcaag ttcctgttga
     2701 taatgccttg gtaaggaaga caattgaatt ttttgcagac aataagtaac taataaggaa
     2761 agcaaatgaa tgctcatctg ttggcatagt atgaaaaaag aattgatttc ctgatcatag
     2821 gaaatagctg gcttactatg ttttagataa tcaattttga actgttcatt tttcagaaaa
     2881 gtaatgatag atgttatttc ttgatctata gaaaaagatt gtcccgtaat atgtgctaat
     2941 aattgctcat caaaataaaa ctggataatg ataaaagttt gtgtttcctt ttgagtagaa
     3001 aagatttgga cttcttgctg tttatcaatg aataaaaggg aaggattatc tagttctata
     3061 gatttatgtg caaattcagc atataaatta gcgctttcat ttattagtag tcgaaaatag
     3121 ggagcagcag ataaatgaag atgggtatct atggaatagg ttagtgtttt tttgacaaga
     3181 ttggaggatt ggttgtttgt taacaaaaga accactttcc tttctctttt tatataaaaa
     3241 gctttctatt tataattaat gactattata acaaaaatga aaagccaaaa cgacaagtaa
     3301 a
//
LOCUS       DACGEU010000154         3292 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.160, whole genome shotgun sequence.
ACCESSION   DACGEU010000154 DACGEU010000000
VERSION     DACGEU010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3292)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3292)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3292
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.160"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            122..433
                     /locus_tag="IXR40_002769"
                     /pseudo
     CDS             122..433
                     /locus_tag="IXR40_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017722130.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
     gene            540..932
                     /locus_tag="IXR40_002770"
     CDS             540..932
                     /locus_tag="IXR40_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4362555.1"
                     /translation="MEEVLIDDNMVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCY
                     TLLRPDGKTMFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRA
                     CHVYEKLGGKNDYKDEIVYVYDYEKGDK"
     gene            933..2372
                     /locus_tag="IXR40_002771"
                     /note="aph(2'')-Ia"
     CDS             933..2372
                     /locus_tag="IXR40_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="HAQ4362556.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYGGRDKKYTLE
                     SLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFI
                     GEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLP
                     EHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYL
                     VNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKE
                     IKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYIL
                     LRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGII
                     DFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPI
                     ETIVYGIKNIKQEFIENGRKEIYKRTYKD"
     gene            2554..3201
                     /locus_tag="IXR40_002772"
     CDS             2554..3201
                     /locus_tag="IXR40_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000143686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type A-8 chloramphenicol O-acetyltransferase"
                     /protein_id="HAQ4362557.1"
                     /translation="MTFNIINLETWDRKEYFNHYFNQQTTYSVTKEFDITLLKSMIKN
                     KGYELYPALIYTIVNIINQNKVFRTGINSEGNLGYWEKLNPLYTVFNKETEKFSNIWT
                     ESNVSFNSFYNSYKSDLLEYKDKNEMFPKKPIPENTVPISMIPWIDFSSFNLNIGNNS
                     RFLLPIITIGKFYSKNNKIYLPVSLQVHHAVCDGYHVSLFMSEFQNIVDSVNEWI"
BASE COUNT         1348 a          271 c          539 g         1134 t
ORIGIN      
        1 ctagtgtgtt atactttaca tggaagttgt accgaaatat tgtgttgtga agtctatata
       61 attttaaaat tatgaagtct atatacgtgc gtaaagatat ttaaagagat taaaaataat
      121 aaaaataaaa attgaattaa aaagagatat ggttgattat tggaacgatt gttttaatga
      181 tttacatata ttacaaccag attggaaaac tatcgaacgt acttctgata gagcaatggt
      241 ttttatgttg ttgaatgatg aagaagaatg gggaaaatta gaaagacgta ctaagaataa
      301 atataaaaaa ttaattaaag aaatatctct aattgattta actgatttaa tgaaatcgac
      361 tttaaaagcg aacgaaaaac aattgcaaaa gcagattgat ttttggcaac gtgaatttag
      421 attttggaag taaagtaact ttgttttata caaaatgtta ctttagtata gtcaagtcca
      481 taatcctgtg taaaatacta tacaatgttt tacacaggag tctggacttg actgagttta
      541 tggaagaagt tttaattgat gataatatgg tttttgatat tgataattta aaaggatttc
      601 ttaatgatac cagttcattt gggtttatag ctaaagaaaa taataaaatt ataggatttg
      661 catattgcta tacactttta agacctgatg gaaaaacaat gttttattta cactcaatag
      721 gaatgttacc taactatcaa gacaaaggtt atggttcaaa attattatct tttattaagg
      781 aatattctaa agagattggt tgttctgaaa tgtttttaat aactgataaa ggtaatccta
      841 gagcttgcca tgtatatgaa aaattaggtg gtaaaaatga ttataaagat gaaatagtat
      901 atgtatatga ttatgaaaaa ggtgataaat aaatgaatat agttgaaaat gaaatatgta
      961 taagaacttt aatagatgat gattttcctt tgatgttaaa atggttaact gatgaaagag
     1021 tattagaatt ttatggtggt agagataaaa aatatacatt agaatcatta aaaaaacatt
     1081 atacagagcc ttgggaagat gaagttttta gagtaattat tgaatataac aatgttccta
     1141 ttggatatgg acaaatatat aaaatgtatg atgagttata tactgattat cattatccaa
     1201 aaactgatga gatagtctat ggtatggatc aatttatagg agagccaaat tattggagta
     1261 aaggaattgg tacaagatat attaaattga tttttgaatt tttgaaaaaa gaaagaaatg
     1321 ctaatgcagt tattttagac cctcataaaa ataatccaag agcaataagg gcataccaaa
     1381 aatctggttt tagaattatt gaagatttgc cagaacatga attacacgag ggcaaaaaag
     1441 aagattgtta tttaatggaa tatagatatg atgataatgc cacaaatgtt aaggcaatga
     1501 aatatttaat tgagcattac tttgataatt tcaaagtaga tagtattgaa ataatcggta
     1561 gtggttatga tagtgtggca tatttagtta ataatgaata catttttaaa acaaaattta
     1621 gtactaataa gaaaaaaggt tatgcaaaag aaaaagcaat atataatttt ttaaatacaa
     1681 atttagaaac taatgtaaaa attcctaata ttgaatattc gtatattagt gatgaattat
     1741 ctatactagg ttataaagaa attaaaggaa cttttttaac accagaaatt tattctacta
     1801 tgtcagaaga agaacaaaat ttgttaaaac gagatattgc cagtttttta agacaaatgc
     1861 acggtttaga ttatacagat attagtgaat gtactattga taataaacaa aatgtattag
     1921 aagagtatat attgttgcgt gaaactattt ataatgattt aactgatata gaaaaagatt
     1981 atatagaaag ttttatggaa agactaaatg caacaacagt ttttgagggt aaaaagtgtt
     2041 tatgccataa tgattttagt tgtaatcatc tattgttaga tggcaataat agattaactg
     2101 gaataattga ttttggagat tctggaatta tagatgaata ttgtgatttt atatacttac
     2161 ttgaagatag tgaagaagaa ataggaacaa attttggaga agatatatta agaatgtatg
     2221 gaaatataga tattgagaaa gcaaaagaat atcaagatat agttgaagaa tattatccta
     2281 ttgaaactat tgtttatgga attaaaaata ttaaacagga atttatcgaa aatggtagaa
     2341 aagaaattta taaaaggact tataaagatt gattatataa tatatgaaaa gctattataa
     2401 aagacattag tattaaatag tttaaaaaaa tgaaaaataa taaaggcttt agtataatta
     2461 acgtttaaga ggtgacacaa tatatgaaaa aatcagagga ttattcctcc taaatacaaa
     2521 gagataagat gaaatttagg aggaaaatta tatatgactt ttaatattat taatttggaa
     2581 acttgggata gaaaagaata ttttaatcat tatttcaatc aacaaacaac ttacagtgtt
     2641 actaaagaat ttgatatcac tttacttaaa agtatgataa aaaataaagg atatgaactg
     2701 tatcctgctt tgatttatac aattgtaaat attataaatc aaaataaagt atttagaaca
     2761 ggaattaata gtgagggaaa tttgggttat tgggaaaaat taaacccttt atatacagtc
     2821 tttaataaag aaactgaaaa attttctaac atttggacag aatcaaatgt tagttttaat
     2881 tctttttata atagttataa gagtgactta cttgaatata aagataaaaa tgaaatgttt
     2941 cctaaaaaac caatacctga aaacacagtt cctatttcga tgattccttg gattgatttt
     3001 agttcattta atttaaatat tggtaataat agtagattcc tattgccaat tattacaata
     3061 ggtaaatttt atagtaagaa taataagatc tatttaccag tctcattgca agttcatcat
     3121 gcggtatgtg atggttacca tgtttcatta tttatgagtg aatttcaaaa tatagttgat
     3181 agtgtaaatg aatggattta aatctaaaat aactttcata aacttaagta attatgatat
     3241 ttataagttt atagcaacca cattttttgg ttgcttgtgg ttttgatttt ga
//
LOCUS       DACGEU010000155         3207 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.161, whole genome shotgun sequence.
ACCESSION   DACGEU010000155 DACGEU010000000
VERSION     DACGEU010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3207)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3207)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3207
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.161"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            40..1173
                     /locus_tag="IXR40_002773"
     CDS             40..1173
                     /locus_tag="IXR40_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HAQ4362558.1"
                     /translation="MWVFGTSAGLITILITVFVTLFLILAAGSIDNSDSSSGGEAFTG
                     EYSEGLPIYKEIKGRGPFSDEIAQYAVGAAVKYKLLPSVILSQYGYESAFGTSASARN
                     DLNYFGITWFDGCLFPKGTARGIGGIEGGWYMKFPNSKAAFSYYGFMVATQSNFNACV
                     GNKSPGASLLILGRGGYAAAGITEDSAYYKNCMSIINTNKLMEYDEFAIKHWREGGGT
                     GGTITGSWGNPFPGSSLDKNSFSGGQLFGKNPGGEFRPNGFHDGLDFGSVDHPGSEIH
                     AVHGGKVVYVGNPGISGLGACVIVINYDGLNMVYQEFANSTGNSRVKVGDQVKVGQVI
                     GIRDTAHLHLGFTRMDWRQAQGHAFIDDGTWIDPLPFLNSSKK"
     gene            1189..1833
                     /locus_tag="IXR40_002774"
     CDS             1189..1833
                     /locus_tag="IXR40_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362559.1"
                     /translation="MENKTLKIVLTAAISVSLIGNIALFWQLKEEQETNTYKIEEVAK
                     NASDKLKKNSSEAQAKIDKLNQTINEKNQEIDQLKQQDGTKAKEEVTEAQRKTAEEFG
                     QLAIDKSLSRNELTEKLKDVATQEVIDKLSPADDDHQHDDYGSYSFTLGDVQTYAQTS
                     SVKEEQNFVVFVDYTIGNPQFKDVKPQKIKGGLTVTEKQVDGQWKVTDFSYFTR"
     gene            1844..2650
                     /locus_tag="IXR40_002775"
     CDS             1844..2650
                     /locus_tag="IXR40_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362560.1"
                     /translation="MSKKKGARQRFKKRKSYLRWLGIFMILGFLILASPIYTHKKVDI
                     PDEVSTNAFLNTKELTMVSKEKGANQQLVFEFAIDDEDQSLLKELANLNYRVEVKTAK
                     GDYQAIKAKVIKVSDDYFVVKLAHVPEEYIAMRLTIIPEKIDPKVDMQEPQDLIYYVH
                     EDKVKDQVKDEDYEQHAINYKVKGYKKEQKAAQKQMESFQATIDLNEELVKKLKDQLP
                     YQVADDQENTENKINSYQQEIETSKTQMKDQEEIIQKLQEKIDRMTKEKI"
     gene            2672..2902
                     /locus_tag="IXR40_002776"
     CDS             2672..2902
                     /locus_tag="IXR40_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362561.1"
                     /translation="MKRTNLADKDTFAEQKVLIKAYLKVVKAKEICREVNLSNTTISE
                     LKNGRKNLDTLKFRSFEALYVAAKKYFTADNK"
BASE COUNT         1182 a          499 c          679 g          847 t
ORIGIN      
        1 aaacagtatg ttaagcgtcg tgcaaagcgg cgcttatttt tgtgggtgtt tggtacttct
       61 gcaggtttga ttactatatt gatcactgtg tttgtgaccc tttttctaat acttgcggca
      121 ggttctattg ataattctga ttcaagtagt ggtggcgaag cttttacagg agaatattcg
      181 gaaggcttac ccatttataa agaaatcaaa ggaagaggcc ctttttctga tgagattgcg
      241 caatatgctg taggtgcagc agtgaagtat aaattattac caagtgtgat cctttcgcaa
      301 tacggttatg aatcagcgtt tggtacgtcg gcgtccgcaa gaaatgatct caattatttt
      361 gggattacgt ggtttgatgg gtgtctgttt cctaaaggaa ctgcgcgtgg aattggtggc
      421 attgaaggtg gctggtacat gaagtttccc aactcaaaag ctgccttctc ctattacggc
      481 tttatggtag ccacacaatc aaattttaat gcttgtgtcg gaaataaaag ccctggcgca
      541 agcttattga tcttaggacg aggagggtat gccgccgcag gaattactga agacagtgcc
      601 tattataaaa attgtatgtc tattattaat acaaataaat tgatggagta cgatgagttt
      661 gcgattaaac actggagaga aggcggcgga actggtggta cgattacagg aagctggggc
      721 aatccattcc caggaagtag cttagataaa aattcgttca gtggaggaca actttttggg
      781 aaaaatccag gaggagaatt ccgacctaac gggttccatg atggactaga ctttggttca
      841 gtcgatcatc caggaagtga gattcatgcg gttcatggcg gaaaagtcgt gtacgttggc
      901 aatcctggta tttcaggttt gggtgcgtgt gtgatcgtga ttaattacga tggcttgaat
      961 atggtgtatc aagaatttgc aaatagtaca ggaaattctc gagtgaaagt aggcgatcaa
     1021 gtgaaagttg gtcaagtaat tgggatacga gatacagcac acttgcattt aggatttact
     1081 cgaatggatt ggcgtcaagc acaaggacat gcattcattg atgatggtac atggatcgat
     1141 ccgttaccat ttttgaatag cagcaaaaaa tagatcagga gaaaaaatat ggaaaataaa
     1201 accttaaaaa tcgtcttaac agctgcaatt agcgttagtt taatcggcaa tattgcgttg
     1261 ttttggcagc ttaaagaaga acaagagaca aatacctata aaattgaaga agtggctaaa
     1321 aacgcgtctg ataagctcaa aaaaaattct tctgaggcac aggcgaagat cgacaagtta
     1381 aatcaaacca tcaatgagaa aaaccaagaa atcgatcagc tgaagcaaca agatggcaca
     1441 aaagcaaaag aggaagtaac tgaagcacaa agaaagacgg cagaagagtt cggtcaattg
     1501 gccattgata aatcattaag cagaaatgaa ttaacggaaa aactaaaaga tgtcgcaacc
     1561 caagaagtga tcgacaaatt aagtcctgca gacgatgatc accaacatga cgactacgga
     1621 agttactctt ttacattagg tgacgtgcaa acttacgctc aaacaagcag tgtaaaagag
     1681 gaacaaaatt ttgtcgtatt tgttgattat acaatcggca atcctcaatt taaagatgtc
     1741 aaaccacaaa aaataaaagg tggattaact gtcactgaaa aacaagtaga tggtcaatgg
     1801 aaagtcacag actttagtta tttcactcgt taggaggaag aaaatgagta agaaaaaagg
     1861 agcaagacaa cgttttaaaa aacgaaaaag ttatcttaga tggctgggga tctttatgat
     1921 tctcggcttt ttgattcttg ctagtccgat ttacacacat aaaaaggtag acataccaga
     1981 tgaagtaagc acgaacgcat ttttaaacac gaaggaactg acgatggttt caaaagaaaa
     2041 aggagcgaac cagcaattag tttttgaatt tgcgatcgac gatgaagatc agagcttatt
     2101 aaaagaacta gctaatctta attatcgtgt agaagtaaag acagctaaag gggattatca
     2161 agcaataaaa gccaaagtga tcaaggtgtc tgatgattat tttgtagtga agttagcaca
     2221 tgtaccagaa gaatatatcg ccatgcgttt aaccattatt cctgaaaaaa ttgatccaaa
     2281 agtggatatg caagaaccac aagatctgat ttattacgtt cacgaagata aggttaaaga
     2341 tcaagtgaaa gatgaagatt atgaacaaca tgcgatcaat tacaaagtga aaggatacaa
     2401 aaaagaacaa aaagcagcac aaaaacaaat ggaatccttc caagcaacca ttgatttgaa
     2461 tgaagaatta gtgaagaagc taaaagatca attgccttat caagtcgcag atgatcagga
     2521 aaatactgaa aacaagatta atagctacca gcaagaaatt gaaacatcga aaacgcaaat
     2581 gaaagatcaa gaagagatca ttcaaaaact tcaagaaaaa attgatcgta tgacaaaaga
     2641 aaagatttag aaggacaggt ggagtgaaaa aatgaagcga acaaacttgg ctgacaaaga
     2701 tactttcgct gagcagaaag tattgattaa agcctatctc aaagttgtaa aagctaaaga
     2761 aatatgtcga gaagtgaatt tatctaatac aacaatatct gagttgaaga atggtcgaaa
     2821 gaatttagat actttaaaat tcagatcatt tgaagctcta tatgtagctg ctaaaaaata
     2881 ttttacagct gataacaaat aaaaaacagg agtattttat gtgaaaaaag tatataaaaa
     2941 atgcttatga atcagctata tcaccttaac catttgttaa tgagatggga gaaaacatta
     3001 accacgattc taacgcaaac atcaagcaca taaaacattt aacactcctc ctttctggct
     3061 gaagatttca accaaacagg aagacagcgt atcaattata gcatacactt tttcttaaat
     3121 tcatttttca tatgacaaaa tatttccttc taatcgacaa agttagaagg attttttatt
     3181 gtctaaatac acaaataacc ttaattt
//
LOCUS       DACGEU010000156         3206 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.162, whole genome shotgun sequence.
ACCESSION   DACGEU010000156 DACGEU010000000
VERSION     DACGEU010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3206)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3206)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3206
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.162"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(301..1020)
                     /locus_tag="IXR40_002777"
     CDS             complement(301..1020)
                     /locus_tag="IXR40_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HAQ4362562.1"
                     /translation="MDEKTELTVKYQNELNLVPLKNFNAKQMDLFFALCARMKDRGLK
                     KVRFSFEELKELSDYKMTATKAFVGDLEKLYKDMLNLTYRTEDEDSIRYFVLFTGFEI
                     NKTKKFVEVSVNPDLEYIINGLTAEFSRFELSAFTSLRSTYAKTLFRLLMQYRSTGYY
                     VVRIEEFRSLMDIPEYYQMGNIDQKVLNPALRELKKYFNDLKVTKIKAKKGNKIAKLE
                     FTFSSLTSDLPKISLRNWLEE"
     gene            1673..1768
                     /locus_tag="IXR40_002778"
     CDS             1673..1768
                     /locus_tag="IXR40_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HAQ4362563.1"
                     /translation="MCFVFTNFICSLLVGLLSALFSYWLNNRNKK"
     gene            complement(2070..2315)
                     /locus_tag="IXR40_002779"
     CDS             complement(2070..2315)
                     /locus_tag="IXR40_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362564.1"
                     /translation="MRLEKEKMEKFPYEYFQNLEKLEQAIQAIKFDLTDEKLLEYKNM
                     TPERKRSLEKLMQLVNEDGGISDAAFDAWSEFHGEYN"
     gene            2661..2945
                     /locus_tag="IXR40_002780"
     CDS             2661..2945
                     /locus_tag="IXR40_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362565.1"
                     /translation="MDILVRNIDPKFVATIDKRCQELTNKTGEKWSRNKYLKVLIESD
                     FDRQLTTYKKDQFDLLLDKFIAIQTENTQILSEYVYTNNQIIEMLIGGMI"
     gene            2948..>3206
                     /locus_tag="IXR40_002781"
     CDS             2948..>3206
                     /locus_tag="IXR40_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362566.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDINNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIIAEFADLYLKDTGV"
BASE COUNT         1065 a          600 c          501 g         1040 t
ORIGIN      
        1 gcgttcttat tggcacaaat tctaaagtat atcaagaagt gaaagaaaaa atcgaagcta
       61 aactaaatcc atcaaatcga aatcgaccaa agaatcatca aaaagaaacc agtcaaacag
      121 tcacttctag aaatttcgac ccaacaaatt ttctaaaacg ataaaaaaca gataggagtt
      181 attcctatct gttttttatt tagaagcccc atacaatatg ctagaatgta ctagcaatct
      241 tagtcggttg taagggactt gtctacttgc ttaatgtaag gggggcgagt tcttttttat
      301 ttattcttct aaccagttac gcagagaaat ctttggcaaa tctgacgtta ggcttgaaaa
      361 agtaaattct aatttggcga ttttattgcc cttttttgct tttatttttg tgactttaag
      421 atcattgaag tattttttta gttctcgtaa tgcaggattt aatacttttt gatcaatgtt
      481 acccatttga tagtattctg ggatatccat taagctccta aactcttcaa tacgaactac
      541 ataataacca gtagaacggt actgcataag cagtcggaat agagtttttg catacgtaga
      601 acgcaacgac gtgaaagcag ataattcaaa tctactaaat tcagctgtta aaccattaat
      661 aatatattct aggtccggat taacactgac ttcaacaaac ttttttgttt tattgatttc
      721 aaaaccagta aacaaaacaa agtagcgaat agaatcctca tcttcagtac ggtaagtaag
      781 attaagcata tctttataga gcttttctaa atcaccgaca aaggcttttg tagcagtcat
      841 cttataatca cttaactctt ttaattcctc gaaagaaaat ctaacttttt tcaaaccacg
      901 atctttcata cgagcgcata atgcaaaaaa taaatccatc tgcttagcat tgaaattttt
      961 cagcggtact aaattcaatt cattttgata tttgactgtt aattccgttt tttcatccat
     1021 tcctttcttc cccccttaca aataaataat aacctttaac aaccaactcg taaataggtt
     1081 ggttgttatt atacaaaagg atattagtac tcagataaaa agttgttagt actcagataa
     1141 aaagttgtta gtactcagat aaaaagttgt tagtactcag ataaaaagtt gttagtaccc
     1201 ttctgtatcc gttgggagag taaggctcaa ctgcccccta aaaagggttc taaaaaatct
     1261 ttaaaaaata aataaaataa acgcgcgcgc gcgagcaaaa tttcccgcca aaaaatcacc
     1321 cactttttaa aataaacagg ttcgcgcatg atattaaact gccaatctag ctccctatgg
     1381 tcgctgtaag aaggagtgat cgctacgctc tcacatttta cttgcagcag tcgcctttag
     1441 gctccttcgc caaaaataat tcattaggga ctcctttgtg gcgtcctgag agctcgtcta
     1501 agccgttcta agacaagatt cgataaaaac tatgtccttc gttctaaagc gccttacagg
     1561 cggtcagggc aagccctaac aaccccaagg caataaaaaa cttaggctta tttttgcttt
     1621 tttattgtat aattgattgt cgcctatccg acagtcttgc gactggaagg aggtgtgttt
     1681 cgtgttcact aactttattt gctcccttct tgttgggctt ttaagcgctt tgttcagtta
     1741 ctggttgaat aaccgaaaca agaagtaaaa cttaattaag gcgactcagc ccacaaaaaa
     1801 agccccagag aatccgacct ctctggggct ttcgtgtgtt tcgtgttcac ttatttgcaa
     1861 tcaaattata acagaaataa atatttattt caaaaatatc ctacaaaagt ctaaaatccg
     1921 taattatttc ttatatgcaa catttacaaa taaagtcgct ctgagagctc gtatttttcg
     1981 atttaagacg ttttatttag tttttggtgt atttcattgg tccaagctaa aaaactctta
     2041 gaagcgattt tagagccatt taaacccact taattatatt ctccatgaaa ttcgctccat
     2101 gcgtcaaaag ctgcgtctga aattccgccg tcttcgttca ctagttgcat taatttttcc
     2161 aacgatcgtt ttctttcggg tgtcatattt ttatattcca acaatttttc gtctgttaaa
     2221 tcgaacttga ttgcttgaat tgcttgctct aatttttcta agttttgaaa atattcgtaa
     2281 ggaaattttt ccattttttc tttctccagt ctcacaattt ttctagaaat aaaatcactt
     2341 ctttgccgtc tatactctca aaaaaaatgt cgtttgaaaa actaaataaa tttttgatcg
     2401 tgcattttta aatttggtta tcgattacac gtgcagcact ccccccccga attttaaaga
     2461 gcataaggaa acgtgtaccc actttctaaa aaaagtgggt agataggctg tgcctatcac
     2521 gtttctcaga aaaaaatttg atatcacttt ttcgccatcg tgggtagctt atgtatagca
     2581 ttttggcaaa aaacagctat acaaatatag tatttgtatg gtatacataa attatacata
     2641 attgcaaaag gagatttttt atggacattt tagttcggaa tattgatcca aagtttgttg
     2701 caacaataga caaacgttgc caagaactca cgaataaaac aggagaaaaa tggagtcgaa
     2761 ataaatatct aaaagtttta atcgaaagtg attttgaccg tcaacttacg acttacaaaa
     2821 aagaccaatt cgatttattg ctcgataaat ttattgctat ccaaacagaa aatactcaaa
     2881 tattaagcga gtatgtctac acaaataatc aaatcattga aatgcttatc ggaggaatga
     2941 tataaccatg agaaaaactt ctgtccaaaa acatgttact ttgtacccta gtcatgttga
     3001 cgttttagat tccatcatcg aaaaaaatcc agatatcaat aactactcgg aagccattcg
     3061 ctttttatgt atgagttatg aacccgatac caacacgacc actaccagca atcaggcaaa
     3121 actaaatgct atgggaaaag aaatttccat catgactgaa atcatcgcag aatttgctga
     3181 tttatatcta aaagatacag gcgttc
//
LOCUS       DACGEU010000157         3183 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.163, whole genome shotgun sequence.
ACCESSION   DACGEU010000157 DACGEU010000000
VERSION     DACGEU010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3183)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3183)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3183
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.163"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(365..1156)
                     /gene="msrA"
                     /locus_tag="IXR40_002782"
     CDS             complement(365..1156)
                     /gene="msrA"
                     /locus_tag="IXR40_002782"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAQ4362567.1"
                     /translation="MLDVEQMEIDLYNIILNRNTREWERTQFEEAKEDLAKMSIKQVI
                     EKLEVNLRPLALRDNLTPDAMDFYLRITGESASAKAYDYAKHKITSPLYQERAIFAGG
                     CFWCMVEPFETKPGVISVLSGYTGGETKKPNYDQVSGGYTGHVEAVEIIFDTRQITYE
                     ELLEIYWQISDPTDAFGQFQDRGKQYRSILFVVNEKQRQLAEKSREQLIQSNRFSRPI
                     VTEIRQAKTFWPAENHHQQFYQKQPKRYKKIKHSHQLHLFFQRHR"
     gene            complement(1347..1982)
                     /locus_tag="IXR40_002783"
     CDS             complement(1347..1982)
                     /locus_tag="IXR40_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HAQ4362568.1"
                     /translation="MIFLQKYGFYFLLLGVISDLSTPYILGLFYPKLNQMTTVISVFG
                     DVDSPVRRAFLVWSVVSGLFFVLSLPALYHLFIGTSKTLAILAVATVGLYGIGDCIFT
                     GLFSINTNESSWNLSTWIHNIGSGLGYAGFLLFPLLLVLLYRQSGQGTLSHFYLVLTV
                     ISLLIAGLYGLARIPSISQFAFFKQLGFFQRLSFFFNYLPMICLSFFQLRK"
     gene            complement(2248..>3183)
                     /locus_tag="IXR40_002784"
     CDS             complement(2248..>3183)
                     /locus_tag="IXR40_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAQ4362569.1"
                     /translation="YFSAYPFAVTIAQLAVIFQLATPLIIGGLIALQFGFDPMRMMVV
                     AGASFVGSGVVKFTPDLGETGVYVGAGTGDIINTMLTASIAVGLILLIGNSFGSVSIV
                     LTPIVVGVGAGLLGFYLFPFVTAITSAIGSLINNFTTLQPLLMSILIGCSFAFLIISP
                     ISTVAIGMAIQLDGVSAGAAAMGVAATTFVLVVNSWKVNKSGVTIAIALGAMKMMMPN
                     LFRKPVILIPCLVSAVITAIPVALFSISGTPASAGFGVVGLVGPLASLDAGLNGFLVV
                     LCWLVIPVFAALITQFLCEKVFKLYDREEVFKFLG"
BASE COUNT         1088 a          679 c          506 g          910 t
ORIGIN      
        1 tagttattgt ttgcgctttt atacggaatt tagttcatca ttaatgtgga attcgattag
       61 gtgtctatta attatcaaga tgattctcta caaaattcca tagaaaaatc aagattctac
      121 aattcgaatt ctctttcaca tggaaataaa ggctagtaaa aaaacaggag ttgtgacaaa
      181 agacttgtca tacctcctgt ttccttgcga cttgaagctg aatgctttgc gccacaacct
      241 tttcctcggt gttctcaaag caactcctcg aaataattca taactgtcca aaaatatgaa
      301 aagctatttt tgtcagttgc tcattatttt gtcggagctg aacgctttgc gccacaacct
      361 tcctctatct atgtcgctga aaaaataaat gaagctgatg cgaatgcttg atctttttat
      421 atcttttagg ttgcttctga taaaattgtt gatgatgatt ttcagctggc caaaaagtct
      481 ttgcttggcg aatctctgta acgataggac ggctaaatcg gttagattga atcagttgtt
      541 ctcttgattt ttcagccaat tgcctttgct tttcattaac aacaaataga attgaacgat
      601 attgtttccc ccgatcttga aattgaccaa aggcatctgt agggtctgaa atttgccaat
      661 aaatctccaa cagctcttca taggttattt gacgtgtatc aaatatgatc tcaacagctt
      721 caacatgccc agtatatcca ccactgactt gatcgtaatt tggttttttg gtctctccac
      781 ctgtataacc agataacact gagattacac ctggttttgt ttcaaaaggc tcaaccatac
      841 accagaaaca gccaccggca aaaatcgccc gttcttggta taagggtgaa gttatcttat
      901 gtttggcata atcataagcc tttgcactcg ctgactcccc tgtgattctt aaataaaaat
      961 ccatcgcatc tggtgtcaaa ttatctcgta gtgctagcgg acgcaagttg acctctagtt
     1021 tttctatcac ctgctttatc gacatttttg ctaggtcttc ttttgcctct tcaaattgtg
     1081 ttctttccca ttctcttgta tttcgattta aaataatatt ataaaggtct atttccatct
     1141 gctccacatc taacatgaag tcaccctctt tcaagttttc ttcttattca ttcaaaaaat
     1201 gactacctga aatttagcac aacgcataac aagttaagac taacttgctt ttcgctctcc
     1261 tcatctctat tcttagtcga acacatccac acgaatggtt acccatagag aaattctttt
     1321 acttaatcag cttcacactg ctttttctac tttcgtagtt gaaaaaaact taaacaaatc
     1381 atcggcaaat agttaaagaa aaaacttaag cgttgaaaga agcccaattg cttaaagaag
     1441 gcaaactgac taatcgacgg aatccgtgct aatccgtaaa gacctgcaat tagtaaacta
     1501 ataactgtta aaacaagata aaaatggcta agcgtacctt gaccactttg acgataaagc
     1561 agaacaagta acaatgggaa aagtagaaag cctgcatagc ctagcccaga acctatatta
     1621 tggatccaag tcgatagatt ccaagagctt tcattcgtat tgatactgaa taacccagta
     1681 aaaatacaat cacctatccc atataaacca actgttgcaa cagcaagtat tgcaagtgtt
     1741 tttgatgttc caataaatag gtgatacaac gcaggcaacg aaagaacaaa aaaaagtcca
     1801 gatacaactg accagaccaa gaaagcacgt ctgactggac tatctacgtc accaaacaca
     1861 ctaattacgg tagtcatttg attcagtttg ggataaaaaa ggccaaggat atacggtgtc
     1921 gataaatcac taatcacacc taataataaa aaataaaaac catatttttg caaaaaaatc
     1981 attttcttct cctacttttt agtgattatt cgatacatcc aacaatcaaa ttttttctca
     2041 ttttaacaca tatttttatt ctagttgcct tttgaacaat caataacata aaggtgagtt
     2101 tcttctacat tttaaaaaat cgaatggcac tgaagagttc agttgtcagc atcaatctcc
     2161 tactcaaaaa ggcaaaaaaa cgtaagtcag atgttgttga catctcactt acgcatccat
     2221 tgattgaaaa tttcttagta aaatctacta gcctaaaaat ttgaagactt cttctcgatc
     2281 atacagttta aatactttct cgcataaaaa ttgagtaatt agtgccgcaa aaacagggat
     2341 gactaaccaa caaagaacaa caagaaagcc atttagccct gcatctaaag aagccaacgg
     2401 accaacaagt ccgaccacgc cgaaaccagc agaagcaggc gtacctgaaa tagaaaatag
     2461 agcgacagga atagctgtaa tcactgcact aactaaacaa ggaataagaa tcacaggttt
     2521 tctaaataga ttaggcatca tcatcttcat agcgcctaaa gcaatcgcaa ttgtcacacc
     2581 tgacttatta accttccaag agttcactac taaaacaaaa gtggttgcag ctacgcccat
     2641 cgcagccgca ccagcagaaa caccatctag ttggattgcc attccgattg ctactgttga
     2701 aataggagag ataatcaaaa aggcaaagga acaaccaatc aagatagaca ttaacagcgg
     2761 ttgtaaggta gtgaagttat taatcaatga tccaattgca gaagtaattg ctgttacaaa
     2821 agggaataaa taaaaaccaa gtaaacctgc acctacacct acaacaatcg gtgttaacac
     2881 aatcgacact gacccaaaac tatttccaat cagtaaaatc agcccgacag caatcgatgc
     2941 tgtcagcatc gtattaataa tatcgcctgt accagcacca acgtaaacac ccgtttcacc
     3001 caaatcaggt gtgaatttga ctacaccaga accaacaaaa gaagctccgg ctacaaccat
     3061 cattctcatc ggatcaaatc caaattgtaa ggcaatcaaa ccaccaatga tcaaaggtgt
     3121 tgctagttga aaaataactg ctaactgtgc gatcgttacc gcaaagggat acgcactaaa
     3181 ata
//
LOCUS       DACGEU010000158         3163 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.164, whole genome shotgun sequence.
ACCESSION   DACGEU010000158 DACGEU010000000
VERSION     DACGEU010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3163)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3163)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3163
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.164"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            147..455
                     /locus_tag="IXR40_002785"
     CDS             147..455
                     /locus_tag="IXR40_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362570.1"
                     /translation="MEVRIRNVDEKIVREIDRRCDELSNRTGNKWSRNDYLKLLVEND
                     FDRPLMEYKQDKFDQLLNQLIDKFSFVQSHNTKVLEEYICQNNQIIELLIEQSRGGEV
                     "
     gene            457..879
                     /locus_tag="IXR40_002786"
     CDS             457..879
                     /locus_tag="IXR40_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362571.1"
                     /translation="MAKVIDKHIYFYETHIDVLDEIIATHAEVKNYSEAVRFLCMNYD
                     SEVEKKVNSNQAKLNAMGKEISILTEMVSEFADLHLKDTGILIGTNSTVYQEAKERVE
                     GKIKANQTKKYSPKIKKTISESVTTKSEVFDPTRFLKR"
     gene            899..2488
                     /locus_tag="IXR40_002787"
     CDS             899..2488
                     /locus_tag="IXR40_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362572.1"
                     /translation="MSKSPAVILTCQFTLPNKKSFSTYIDYMTREKALEEKERRTPEE
                     EQELRLIKNALEDFYIPEGETFSESKTGKEFSETSNEAQSLMKHGINFDKLEEQDFTK
                     YLSYMTRHYALEQKKVLTHSEQKEYQRLNQAIKKYQTEPHKKASGNLPGVFSMASDEV
                     KGSDLKEIKQTFQRGQQKGSIIYQDVVSHDHSYLEKIGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNTKHIHIHFAVVEKKNTRKPYTEIENGVSYIVPKG
                     KRRQATLDEMKTNYVHELERFSYEKNRMGMEKRNLLTRKSDLRNTLTKVVKEPVRYDR
                     HAMSLLTEVYKNLPKKRSEWHYGDENRTKLSPYTREKLDELTQYVLTKEPGYQEYIQI
                     SKALKEEAKSLYGESKRESKDAEKNALFDLKKRTGNAILTELKKQDSQIKPLIERMDQ
                     MQSIYNERSFRTLKQLPTNEYKYSYEEFMKRRKQFQQRVVTQRSLRQLNRTINAHEEK
                     YHASKAYEEQQRRIQMEQERQ"
     gene            2500..2835
                     /locus_tag="IXR40_002788"
     CDS             2500..2835
                     /locus_tag="IXR40_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362573.1"
                     /translation="MKQYLDQWKVIEGSLREERIEQLPDCLEKEHLFQIREMLINEQF
                     DPNQFLVVEYPATGVYCCNHVKGEKYFIIQEYEGKLAPYYTTWEMNEEGINNFPCKSI
                     EESISLTEC"
     gene            2976..>3163
                     /locus_tag="IXR40_002789"
     CDS             2976..>3163
                     /locus_tag="IXR40_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362574.1"
                     /translation="MAYSTIGVVVEKSRDNLVFVTEIQTGRAFVVTDKAAKAYQSGDI
                     LTLNLTTKTFVDAAEDYP"
BASE COUNT         1264 a          453 c          640 g          806 t
ORIGIN      
        1 attacgtttc tcaaaaataa ttgtgggaac aaaatattta aaaataggat agtgaaagga
       61 tagcaaagga tagtaaaagg atagaagcag gatagcgaaa aggataggct ccttttcgct
      121 atccttttta aattggagga attaatatgg aagtaagaat aagaaatgta gatgagaaaa
      181 tcgtaagaga aattgatcga agatgtgacg aactaagtaa ccgaacgggt aataaatgga
      241 gtcgtaacga ttatttaaag ctactcgttg aaaatgattt tgatcgtcct ttgatggaat
      301 ataaacaaga taaatttgat caattattaa atcagttaat agataaattt tcttttgttc
      361 aaagtcataa tacaaaagta ttagaagaat atatttgtca gaataatcaa attatcgaac
      421 ttttaattga acaaagtaga ggaggagaag tttaacatgg ccaaagttat agacaagcat
      481 atttattttt atgaaacaca tatagatgtt ctagatgaaa ttattgcaac tcatgcagag
      541 gttaaaaact atagtgaagc cgttcggttt ctatgtatga attatgattc agaagtggag
      601 aaaaaagtaa attccaatca agcaaagttg aatgcaatgg gaaaagaaat ttctatttta
      661 accgaaatgg tttcagagtt tgcggatctc catttgaaag atacagggat tttaattggt
      721 acaaattcaa ctgtttacca agaagcaaaa gagcgtgtgg aaggcaagat aaaagcaaat
      781 caaacgaaga aatattctcc taagataaag aaaacaataa gcgaatcagt gactacaaaa
      841 agtgaagtat ttgatccaac aaggttctta aaacgataaa aattagaagg agaatgtgat
      901 gagtaaatca cctgcagtca ttctcacttg tcaatttacc ttgcccaata aaaaatcttt
      961 ttcaacatac attgattata tgacaagaga aaaagcgctg gaagaaaagg aacgacgtac
     1021 gcccgaggaa gaacaggaac tgcgtctaat caagaatgct ttagaggatt tttatattcc
     1081 tgaaggagaa actttttcgg agagtaagac gggtaaagaa ttcagcgaaa cgtcgaatga
     1141 agcgcaatcg ttgatgaaac atggaatcaa ttttgacaag ttagaagaac aagattttac
     1201 caaatatctt tcttatatga cacgtcacta tgcgttagaa caaaagaaag tactgacgca
     1261 tagtgaacaa aaagaatacc aacgcttgaa ccaagcaata aaaaaatatc aaacagagcc
     1321 acacaaaaaa gcttcaggaa atcttcctgg agttttttct atggcttcag acgaagtgaa
     1381 aggaagtgat ctgaaggaga tcaagcaaac cttccaaaga ggacaacaaa aaggctcaat
     1441 catttatcaa gatgttgtct ctcatgatca ttcgtatctt gaaaaaatag gattgtacga
     1501 tcccaaaaca gatactttag atgaagaagg tttaaaagca gctggaagaa aaatgatgga
     1561 gacattgttc gagaaagagc aactgaatga aacaggctac tggatggcaa cgattcaccg
     1621 aaataccaaa catatccata ttcattttgc agttgttgaa aaaaaaaata cgcgtaaacc
     1681 atacactgag attgaaaatg gtgtgagtta tatcgtaccg aaagggaaga gaaggcaagc
     1741 aacattagac gaaatgaaga ctaattatgt acatgagtta gaacgttttt cttatgaaaa
     1801 aaatcgaatg ggtatggaga aacgaaattt attgacacgg aaaagtgatt tgcgtaacac
     1861 cttaaccaaa gtagtgaaag agccagtacg ttatgatcga cacgcaatga gcttattaac
     1921 tgaagtatat aaaaacttac ctaaaaagcg ttcggaatgg cattacgggg atgaaaatcg
     1981 aaccaaactt tcaccataca caagagagaa actcgatgag ttaacccaat atgtgttaac
     2041 aaaagaacct ggatatcaag aatatataca gatttcaaaa gcattgaaag aagaagcaaa
     2101 aagtctttat ggggaaagca agagagaatc aaaggatgca gaaaaaaatg ctctctttga
     2161 tttaaaaaag cgcacaggaa atgccattct aacagaactg aagaaacagg atagtcaaat
     2221 aaaaccttta atagaaagga tggatcagat gcaatctatt tacaatgaac gatcctttcg
     2281 aacacttaaa cagttgccaa cgaatgaata caaatatagt tacgaagaat tcatgaagcg
     2341 caggaaacaa ttccaacaaa gagttgtcac gcaacggagt ttgcgtcaat taaatcgaac
     2401 gattaatgcc catgaagaaa aataccacgc aagtaaagca tacgaagagc aacaacgaag
     2461 aattcaaatg gaacaagaaa gacagtagga ggaatagcaa tgaaacaata tttagatcaa
     2521 tggaaagtta tagaaggatc attaagagaa gaacgaatcg aacaacttcc cgattgttta
     2581 gaaaaagagc atttgtttca gataagagaa atgttgataa acgaacagtt tgatccaaat
     2641 caatttttag tcgttgagta cccagctact ggtgtgtact gttgtaatca tgtgaagggt
     2701 gaaaaatatt ttatcattca agaatatgag ggcaagttag cgccttatta tactacttgg
     2761 gaaatgaatg aagaggggat caataacttc ccgtgtaaaa gcattgaaga gtctatttca
     2821 ctcacagaat gttagttgtt aagtgaataa aagaagtaaa agagtcctga acgtgattgt
     2881 ccaggactct tttttttcac tgaattgttt tccgccaatt cattgagtgg tgcgatttcc
     2941 gtctacatta tatcaaaaga aaggaggaag aagaaatggc ttattcaacg attggagttg
     3001 ttgttgaaaa aagcagagac aatcttgttt ttgtgacaga aattcaaaca ggcagagctt
     3061 ttgtagtcac agacaaagcg gcaaaagcat atcaaagtgg cgatatttta acgttaaatc
     3121 tgactacgaa gacgttcgtc gatgcggcag aagattatcc att
//
LOCUS       DACGEU010000159         3138 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.165, whole genome shotgun sequence.
ACCESSION   DACGEU010000159 DACGEU010000000
VERSION     DACGEU010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3138)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3138)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3138
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.165"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            <1..651
                     /locus_tag="IXR40_002790"
     CDS             <1..651
                     /locus_tag="IXR40_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HAQ4362575.1"
                     /translation="AESFDKKHRHVLTAIDELKEGVAENWADLFWEDTYVHPQNKQSY
                     RIIYMNRDGFSLLAMGFTGKKALSFKLQYIEAFNKMEKELKDQLPSIPATKREMALLA
                     LAANEETNERVDAIESDLNDLKNNQLLAEPDYRTISNMVRNKIRVICNQQHLNSKAKA
                     ELFKDLNGGIKRITGAVARNRIKAKQFDDVIDFINNWMPSTATMTIIKQMELLEDE"
     gene            830..1171
                     /locus_tag="IXR40_002791"
     CDS             830..1171
                     /locus_tag="IXR40_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362576.1"
                     /translation="MKKELSTLDQYLTDPSWGKSNIKETSNRKIRRNLLTDEELACDQ
                     DDLGNFVSIWDHVYLIHLSRKSKKTEYIYVIEDGLIDALEEYDRDNLIDISYYGSGKK
                     YIAEMEAEFDE"
     gene            1164..1910
                     /locus_tag="IXR40_002792"
     CDS             1164..1910
                     /locus_tag="IXR40_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HAQ4362577.1"
                     /translation="MSEKEQPLKNRSDNTLFNTLYKINVKDVTEKRNNLTYLSWAWAW
                     AEVSKVCEAVDYEIYHDPETYLPYVFDKKTGYMVFTSITVNGVKRDMWLPVMDGANKA
                     MKDEPYTYEVNDYQWNNETKKKEIVGKIEKRVEAATMFDINKTIMRCLVKNLAMFGLG
                     LYIFAGEDMPEDVSMLEPATQRSKKLFLDALQLVANKYEKSIDEAIVALTDAASITAD
                     DSKWTKRDLGILKRGVNWIEDQYREETKEK"
     gene            1916..2602
                     /locus_tag="IXR40_002793"
     CDS             1916..2602
                     /locus_tag="IXR40_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362578.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDIGATINEEVNIDRLKTMYDGYDGD
                     RIIEVRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHSEYTFAALCRIHHTEKHNIGVINFKNKYQIKGIKLNQ
                     ETIKKLRIGG"
     gene            2609..>3138
                     /locus_tag="IXR40_002794"
     CDS             2609..>3138
                     /locus_tag="IXR40_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer"
                     /protein_id="HAQ4362579.1"
                     /translation="MSDNKRYYYLKLKENFFDSDEMVLLESMPDGYIYSNILLKLYLR
                     SLKHEGKLMFNDRIPFNSTMLATITRHSVGVVEKAVQIFRDLQLIDVLDNGAIYMSDI
                     QSFIGKSSTEADRKREYRKKIEEAKRNLITGGQVSDKCPDKTTPELEIEIEKDIDIDK
                     EEKKGKYSDEHLRLAK"
BASE COUNT         1181 a          500 c          649 g          808 t
ORIGIN      
        1 gcagaaagct tcgataaaaa gcacagacat gttttgacgg ctattgatga actaaaagag
       61 ggggttgccg aaaattgggc agacctattt tgggaagata cttatgttca tcctcaaaat
      121 aaacaatcat accgaattat ttatatgaat agagacggct tctctctatt agcaatgggc
      181 ttcactggta agaaagcttt aagttttaaa cttcaatata ttgaggcctt caacaagatg
      241 gaaaaagaat taaaagacca attgccatca attccagcaa ctaaacgaga aatggcatta
      301 cttgctctag ctgcaaacga agaaacgaat gaaagagtag acgctatcga gtctgattta
      361 aacgatttga agaacaatca acttctagct gaaccagatt accgaacaat ttctaatatg
      421 gttcgcaaca aaattagagt tatttgtaat cagcagcatt taaatagcaa agcaaaagca
      481 gaattgttta aagacttgaa tggcggaatt aagcgaatca ctggagcagt agctagaaat
      541 cgtatcaagg caaaacagtt cgatgatgtt atcgatttta ttaacaattg gatgccttct
      601 acagcgacga tgacaattat taagcaaatg gagttgttag aggatgaata gagctgaagc
      661 gctaaaaata ggcgtaataa ttgctaatcg ctggtggaga cacaataaac caaacatcct
      721 aagccaacaa catattgata agcaaaaagc atggcaacaa ataaaaaagt gactcagccg
      781 accaaagcaa tgagtcacaa agaaaataca tctaaggaga tgttaccaca tgaaaaaaga
      841 actttccact ctagatcaat atttgactga tcctagttgg ggcaaatcga atatcaagga
      901 aacaagcaat cgaaaaatca gacgtaatct tttgacggat gaagaactag catgtgatca
      961 agacgatttg ggaaattttg tgagtatttg ggatcatgtc tatcttatcc atttatcgag
     1021 gaagtccaaa aaaactgaat atatctatgt catcgaagat ggcttgattg atgcgctaga
     1081 agagtatgac agagataact tgattgatat ctcttattac ggatcaggta agaaatacat
     1141 tgctgaaatg gaggcagaat ttgatgagtg aaaaggaaca acctttgaaa aatagaagtg
     1201 ataatacgct ttttaatacc ttatacaaaa taaatgtgaa agatgttact gaaaaacgaa
     1261 ataacctcac ttatctttcg tgggcatggg cttgggcaga agttagcaaa gtgtgtgagg
     1321 cagtagatta tgaaatctat catgatccag aaacatatct gccgtatgtc tttgataaga
     1381 aaacaggcta tatggttttt accagtatca cagtcaacgg agtaaagcgt gacatgtggt
     1441 taccagtcat ggatggtgca aacaaggcaa tgaaagatga gccatatacc tacgaagtca
     1501 atgattatca gtggaataac gaaacgaaga aaaaagagat tgttggaaaa atcgaaaagc
     1561 gagttgaagc agcaactatg tttgatatca acaaaacgat catgcgctgt cttgtaaaaa
     1621 atctagcaat gtttgggcta gggctatata tatttgctgg cgaagatatg ccagaagatg
     1681 tctcgatgct tgaaccagct actcaaagaa gcaaaaagct attcttggat gctttacaac
     1741 tggttgctaa caagtacgaa aaatcaattg atgaagcaat tgttgcattg actgatgcgg
     1801 cttctataac cgctgatgac agtaaatgga ccaagagaga cttgggcatt ctaaaacgag
     1861 gcgttaactg gattgaagat cagtacagag aagaaacaaa agagaagtga tatgagtgtt
     1921 taaaccattg atcgattcat attcagcggt tctgaaaaag ttcaaaggaa aagacatagg
     1981 tgcaacgatc aatgaagaag tgaacattga tcgactaaag acgatgtatg acggatatga
     2041 tggcgatcgg attattgaag ttcgatttat tgatccacgt cgatttactg tgcagcaacg
     2101 aaacttcatc tatgcgctga taggcgatat tttcatcgat acaggcatgc caacggactt
     2161 ctggaaggaa ttcttttact tccgttttga aggcgtcaca gggcgcaaaa taagcctcaa
     2221 agacgaatcg aatacaactg tgagtgatgc taatgtctta gcaaatatca tcttagattt
     2281 catctttgaa catcatattc ctttcaaaga aggctatgag attttaccag cgaatcaaga
     2341 atattacttc tacaaatgca tcacaaaaag agtctgctgc atctgtggca aaacaggagc
     2401 tgacatcgat cactttgaca aagcgctagg aagacgaaag cgcaaagaag ttgatcattc
     2461 agagtacaca tttgcagcac tctgcaggat tcatcacacg gagaaacaca atataggtgt
     2521 gatcaatttc aaaaataaat atcaaatcaa agggatcaag ttaaaccagg aaacaattaa
     2581 gaaacttaga ataggagggt aaaaaatatt gtctgacaac aaacgctact actatttaaa
     2641 actaaaagag aattttttcg atagtgacga gatggttctc ttagaaagta tgccagatgg
     2701 ctatatttat tctaatattc ttctcaaact ttatttaaga agtctaaaac acgaaggtaa
     2761 gttgatgttt aatgacagga ttccatttaa ctctacaatg ctcgcaacta ttacaagaca
     2821 ttctgtagga gtcgtagaaa aagcggtaca aattttccgt gatttgcagc ttattgacgt
     2881 attagataac ggagcaattt atatgtctga tatacaaagt ttcattggaa aatcctcaac
     2941 tgaagcagat agaaaaagag aatacagaaa gaaaatagaa gaggcaaaac ggaatttaat
     3001 aactggagga caagtgtcgg acaaatgtcc agacaaaact acaccagagt tagagataga
     3061 gatagagaaa gatatagata tagataaaga agaaaagaaa ggtaagtatt ctgacgaaca
     3121 cttacgcctt gctaaaaa
//
LOCUS       DACGEU010000160         3040 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.166, whole genome shotgun sequence.
ACCESSION   DACGEU010000160 DACGEU010000000
VERSION     DACGEU010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3040)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3040)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3040
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.166"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(28..963)
                     /gene="murB"
                     /locus_tag="IXR40_002795"
     CDS             complement(28..963)
                     /gene="murB"
                     /locus_tag="IXR40_002795"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HAQ4362580.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(1036..1956)
                     /locus_tag="IXR40_002796"
     CDS             complement(1036..1956)
                     /locus_tag="IXR40_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAQ4362581.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            2069..2821
                     /gene="xth"
                     /locus_tag="IXR40_002797"
     CDS             2069..2821
                     /gene="xth"
                     /locus_tag="IXR40_002797"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HAQ4362582.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
BASE COUNT          856 a          612 c          526 g         1046 t
ORIGIN      
        1 tttacttatt ttaagttcca ttacttatta attggctaaa cttctgcttg tttctgatat
       61 tgcttgtttt tctccaatga tccgcacttc tgtttctaaa gacacatcaa atttttcttt
      121 gattacttct tggatgtgcg caatcaattc aatataatct gtcgctgtcg catgatcgat
      181 attgacgatg aatccagcat gtttttcaga gacttgtgca ccgccccatt tcaggccttg
      241 caatcctgct tgttggatca gctgacctgt atagtgtcct actgggcgct taaagacact
      301 tccgcatgaa gggtattcta atggctgttt tgattgacgc aattcggtca actcatccat
      361 tcttgctttg attgcttcat aatcccctgt ttgcaaactg aatcgagctt ccaatacgat
      421 agcacgtaat tcttggactt tactgtgacg ataagaaaat accatttcgt cttttgtcaa
      481 agttttcaat gttccatctt caagcaaaag atccacttca gcaaaaacat ctttgatctc
      541 tccgccatac gcacctgcat tcatataaac cgctccaccg acacttcccg ggatgccgca
      601 agcaaattca aatccagtca atgattctgc caaagctgca taagtcgtat caatcagtga
      661 ggcacctgct tccgcaatga ccatcgttcc tttgacatga atctgtttca tttcagtcag
      721 catgatgact acaccgcgaa tcccgccatc ttgaacgatc agattgcttg catttcctaa
      781 taccatccaa ggtatatcat ggattcggca ataatcgatg atttgcttta cttcttcttg
      841 ttttttcggg aatgcaagga catcagctgg tccacctgtt ttcgtaaacg tatagttcat
      901 caatggttca tcaaacaata tagtaatcgt ggctaagctt tcaactattt cttctttatt
      961 cactgaggat tttcctttct tttctcaaac gtcctcatta ttctatcacg cttaatacaa
     1021 tcttgccagt cttgttcaaa gttgatgacg gtagtgatct ttaagcactt cctcacataa
     1081 ttcatgactt cttacaactt ctttttgttt aagcaattct gtttccgatt tacctaaacg
     1141 gatctgagaa aagaaggcct ctaccattgg ctcaaacccg cgtttgacta gcgtgtttgt
     1201 ccagtcgcca aattctttca ctttttttcc atcagcatct tgaatgacaa gctgggtcag
     1261 atcgtttact tcataagtac catttttact tgttacttga tatttttcta tattagcgcc
     1321 acttgctaaa tccatcgtta aaatagccgt ttgattttgt gtttctaatt gtaaaatggc
     1381 atattccaaa aattcctttg tttctcttat ctggtatttt gttctcaaaa tgggttcatc
     1441 taataaatac acagctgtat caataagatg taaaaacaaa tcataaagga cgaactctgt
     1501 cgtttctttt gccgctattc gatttttttg caggtggatc aaccgcttat ctgggatacg
     1561 tttcaattct tctaccatag gagcaaagcg ccggttgaaa ccgatcatca aaattatttg
     1621 gttcttatca gctaattctt gcaattcacg aacttcattt agatggacac tcagtggttt
     1681 gtcaatataa acatggatac cattttctag acattttttg gctaattcat aatgtacttt
     1741 tgttgctgcg tggatcatac atgcttcgat tttttcttct aaaagctcat cgatcgtttc
     1801 atatagatgt tggaacccgt actctttttg aattctttct tttgtttctt tatttcttgt
     1861 tgcaaaataa aaatcaagtg ttccttgttt tttcgcataa gttggtaaat atgctttttc
     1921 tgcgatattc cctacaccga ttacaccaat cttcatctac tttcctcctg gatcatttag
     1981 ttactttcat cttacaccat tttttactaa aatgaggtac aatagtatcg caaaggtaag
     2041 gaaattaatt cgaaggagtg tgcttttatt gaaatttatc tcttggaacg taaacgggct
     2101 tcgtgccatc gtaaataaaa attttttaga agtttttcat gagttagacg ccgatttttt
     2161 ctgtctgcag gaaacgaaac tccaagcagg acaaattgat ttagatcttc caggttatta
     2221 tcaatattgg aattacgcgg aacgaaaagg ctattccggc acagcgattt ttgctaaaaa
     2281 accagcattg aatgccactt acggaatggg tatcgatatc catgatacag aaggccgtct
     2341 gattactttg gaatattccg atttctttct tgtaacctgt tacacgccaa attctcaaag
     2401 cgaattaaaa cgtttagatt accgattaga atgggaagaa gccttttata attatttgga
     2461 aaatctaaaa aaacaaaaac cagtcatcgt gtgtggggat ctaaatgtcg ctcatcaaaa
     2521 gattgatttg aaaaactgga aaacgaatca aaaaaatgct ggattcactc cagaagaaag
     2581 agcggctctt tctcgactgt tggataacgg gtttatcgat acattccgtt atttttatcc
     2641 aacccaggaa ggtgtctact cttggtggaa ctaccgattc aattcaagga aaaacaatgc
     2701 tggttggcgg atcgattact ttttgacgag caaagattta gagccaggac tagctgatgc
     2761 aaagatccat acggacatta tgggcagtga tcattgtcca gtagaattag atttgaaata
     2821 aagaggttgt gaaaaagtcg tttagtttcg agtattaaga aaaattttgt gaaaatggct
     2881 ttccacattt tgcataaatt tggcataata ccgagaaact ggcttttgaa cactgtttat
     2941 cgagagattg tgaaaaagct gtcctgcatc aagtaataag aacagccaaa caaaaatagt
     3001 tcctcatatt tttcgtttgg ttgggcttat taccgcagat
//
LOCUS       DACGEU010000161         3032 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.167, whole genome shotgun sequence.
ACCESSION   DACGEU010000161 DACGEU010000000
VERSION     DACGEU010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3032)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3032)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3032
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.167"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            107..1195
                     /locus_tag="IXR40_002798"
     CDS             107..1195
                     /locus_tag="IXR40_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362583.1"
                     /translation="MYSKNWKKKLVMGVMVGSIFVFAGCSASTDKSKTATSETKTAEV
                     VKSKMKQIEKNVEKILAEKDKDTKLSEYKKFVTESSAYSKSDKTEKKITNTYTESIKK
                     IKTNFKEQDDKDLKENTLDNLEEATENDLSQKVNTLDELKKWVQKESTDVYSQAEVDS
                     LIKKIDDTITTYKNQLEKIKIDNQEATSTETTTESSEVATLQENVSEEPQVVHTNLLN
                     SIEEAAQYLGQKLPQSGGSDAFENGQQNSDGSFTFHYQLHGGPEGITWNIITVNNNGE
                     IIQDDYFKTVPNEATNNNVSTLSQAAISELEAAQLAIAKHNELGRPNATDAGSETTAD
                     GYYFYYMADGTDQMYKYFVSNSGQVQAE"
     gene            complement(1652..1819)
                     /locus_tag="IXR40_002799"
     CDS             complement(1652..1819)
                     /locus_tag="IXR40_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000251833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362584.1"
                     /translation="MSIREIVRIQSFPDSYIFVGSSLSAKYKVIGNAVLPKLAKVIGD
                     SIVKQLSESNF"
     gene            1864..2286
                     /locus_tag="IXR40_002800"
                     /pseudo
     CDS             1864..2286
                     /locus_tag="IXR40_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752995.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
BASE COUNT         1166 a          441 c          495 g          930 t
ORIGIN      
        1 taaatggctt ttttatttgt ctcgcttaat tatacaaacg gcgtcaatat aaccactttt
       61 atgaaaagat gttataatta actaaaaaat aatagggaga aaacacatgt actcaaagaa
      121 ttggaaaaaa aagttagtga tgggtgttat ggtagggtct atttttgttt ttgcaggttg
      181 ttcagcttcg acagacaaaa gtaaaacggc tacttcagaa acaaaaactg ctgaagtagt
      241 aaaaagtaaa atgaaacaaa tagaaaaaaa tgtagagaaa attttagccg aaaaagataa
      301 agatacaaaa ctgtcggagt acaaaaaatt tgttactgaa tccagtgctt actctaagtc
      361 agataaaacg gagaaaaaaa ttactaatac ctatacagaa tctattaaga agatcaaaac
      421 aaattttaaa gaacaagacg ataaagactt aaaagagaat acactagata atcttgaaga
      481 agcaactgaa aatgatcttt ctcaaaaagt aaatacatta gatgaactca aaaaatgggt
      541 acaaaaagag agtactgatg tatatagcca agcggaagta gattcattaa tcaaaaaaat
      601 tgacgataca attaccacat ataaaaacca actagagaaa ataaaaattg ataatcagga
      661 ggctacatca acagagacta caacagaaag tagtgaggta gctactttac aagaaaatgt
      721 ttccgaagaa ccacaagtgg tccacacgaa tttattaaat tctattgaag aagcagctca
      781 atatctggga caaaaacttc cacaatcggg cggttcagat gcatttgaaa atgggcaaca
      841 aaattctgat ggctcgttta cttttcatta tcaactacat ggaggtccag aaggtatcac
      901 ttggaatatc attacagtga ataataatgg tgagattatc caagatgatt atttcaaaac
      961 tgtacccaat gaagcaacaa acaataatgt ctctacactt agtcaagcag ctatttcaga
     1021 gttagaagct gctcaacttg caatagctaa acacaatgag ttaggtagac ctaatgcaac
     1081 tgatgccgga agcgaaacta cagcagacgg atattatttt tattatatgg ccgatggaac
     1141 tgatcagatg tataaatatt ttgtaagtaa ttctggtcaa gttcaagcag aataacattg
     1201 agttataatg atattatcag atgaactgta tcataaattt ttaacgtgaa atgtttgtaa
     1261 tatcaattgg agaatggtat atggatttac taaaagataa taactgttat tttttagtaa
     1321 attcatacta tttagaaaag aataatttgc tgaatacttg taaactatgt gtgatactta
     1381 tcttatatgg atatagactc gtggtgctag ttaatttcag cttattataa accaacattt
     1441 tcattttata aaaacgacta aaaacagaat ttctgagtaa aatttcaaaa gtaaaaatag
     1501 tgatattatg ctcttgttcc tagattcaat aattaactag caccacgagt ttataaaatt
     1561 ggcaataaaa ttttaatcat tattaacata acctggatct gtaaagcaat ttaactctta
     1621 ataaaaaagc atctaaaaaa agcgtgttca gctaaaagtt tgattcagaa agttgtttaa
     1681 ctatagaatc accaattact tttgcaagtt ttggtagaac agcattacca attactttat
     1741 attttgctga aagagagcta ccgacaaaaa tataactatc tggaaatgac tgaattctca
     1801 ctatctctct tatcgacact cttagatgaa ctcaaaaaaa tgggtacaaa aagagaatac
     1861 tgatgtatat agtcaactag aaatatcgct catagagtgc gtgttcgagg tcgaaaagaa
     1921 atctgtgagg agttcaaatt gatttaccat gcgaattcaa aagaagaggc attgaattac
     1981 atcgatttta tgattaggaa atggaaaaag caggatcgaa gagtcgtgaa cctactcttg
     2041 aatcctgccc tattaacctt ttataatttc ccttacgcta tcagacgaac aatttattca
     2101 acgaacctga ttgaaggctt taataagcag ctaaaacgat atactcgaag aaaagaacaa
     2161 ttccctaatg aagaatctct ctagagattc ttagcttcgc aattcaacta atataaccag
     2221 aaatttttaa gtagagttca caaaagattt aaagaaattc aagatacatt agagtcgatg
     2281 atttaactgt aattaacaga atggattttc catttacaca taattcttga cgctacctca
     2341 taataattaa gagctttaaa attagtattt attagatact taaaagctat tttagtattg
     2401 ataaattgtt accagcaaca aaaaagaagt tacttagtgc taacttttga gcaactgcta
     2461 gaggaggtag gatatggcta attatcctgt aatttttatt gtattttcta gaaatgtaat
     2521 tattctctta aacattccag catatccaag tatatagaaa atttacgttt tctatatagt
     2581 tggatgttta caagttatat ctggtttaat aagttttttt ctgttagtca tggcatgttt
     2641 tattgtgctg gttcatcaat atattgaaat gtactaaaat gaaattttca gttatggtat
     2701 aatatttatg ctgtctgcta ccccggccta ttatggcaag gggaggaggt tgtattatga
     2761 attacctttt cgatatgttt tttgcaatct tagcagaagt atccgcgcat tacatctgta
     2821 aatggcttga ttgcaaaatt attgccaaaa aagacagtaa gcctacccgt taatctgaat
     2881 agaacgtaaa agaaaaccac tagcccgcca gctagtggtt tttggtgtat catgaattac
     2941 cttttcgtta aaacaattat accatatttc ctaaaaaata caattaatag acgaattatc
     3001 attaccactt tgatgaaaaa agctgacata aa
//
LOCUS       DACGEU010000162         2946 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.168, whole genome shotgun sequence.
ACCESSION   DACGEU010000162 DACGEU010000000
VERSION     DACGEU010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2946)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2946)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2946
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.168"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..941)
                     /locus_tag="IXR40_002801"
     CDS             complement(<1..941)
                     /locus_tag="IXR40_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAQ4362585.1"
                     /translation="MKKKIFVGAIIALFLLPINAFAYSINNEFNLGANEGSSQVANNQ
                     YILLHETANETATGRNEAQYMKRSWYNAYTAYIVGDGGIVYQVGQPGYVQYGAGSYAN
                     ANSPVQIELQHTHDKVTFEKNYKAYVELARDSANKYGIPLTLDTPYNQPGIKSHLWVT
                     QNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAANPTL
                     SDGTNHSHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIYRPD
                     VNQAYNTSGNVGYHVSFNMRNFPNKKVYVMMRATNDP"
     gene            complement(938..1327)
                     /locus_tag="IXR40_002802"
     CDS             complement(938..1327)
                     /locus_tag="IXR40_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HAQ4362586.1"
                     /translation="MTGVIGGTIVGLLGGMDNILHVLIFLVGVDFLTGLAKAWKLKEI
                     SSEIGFEGLLKKVLIFVVIAVAVDVQKIVGNSIPLREIVIMFYVANEGISFLENISVF
                     LPLPDKLKEVFQQIRNDTENKDRGGTK"
     gene            complement(1427..1567)
                     /locus_tag="IXR40_002803"
     CDS             complement(1427..1567)
                     /locus_tag="IXR40_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HAQ4362587.1"
                     /translation="MNSFPGFENIKQFYDWGCYTDQDLLDYVNMNCLTKDQYKQITGN
                     EI"
     gene            complement(1560..1907)
                     /locus_tag="IXR40_002804"
     CDS             complement(1560..1907)
                     /locus_tag="IXR40_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362588.1"
                     /translation="MKAAYRPIEPYGFEQIILNNQENIPENCTEIKPPVPNWRPRFDF
                     DKKQWVELATEEEKSGTAVDDIEDVDQLKQLNALLTKQLAISVQEQEKMQQMLAQLTM
                     EVASIKNGGKSNE"
     gene            complement(1924..2220)
                     /locus_tag="IXR40_002805"
                     /pseudo
     CDS             complement(1924..2220)
                     /locus_tag="IXR40_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176405.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(2446..2946)
                     /locus_tag="IXR40_002806"
                     /pseudo
     CDS             complement(2446..2946)
                     /locus_tag="IXR40_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338872.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          784 a          613 c          499 g         1050 t
ORIGIN      
        1 tctggatcat tcgttgcccg catcatgacg tatactttct tattagggaa attgcgcatg
       61 ttaaaagata catgatagcc aacgtttcca gaagtattat aagcttgatt tacatccggt
      121 ctataaattc catcagctct tactcgagct aattctttcc cagtattgta gtccataatg
      181 aaaatatact cgtatttata gttagcgatg tgccatccag cgacgtgtaa gttcgcattt
      241 tcgatttctc caaactgatc aatgtgagaa tggttcgttc catctgataa agttggattt
      301 gctgcacctg ctcgggttgg atcaatgaca ggcttgttct cagaagtcgt tgggttttcg
      361 tctgtaaatc catgagctaa atcgtaagcc agtttttcct tacttacacc catttctgat
      421 aagtatccat acggatcagt gtgatcgccc caaatgtttt gagttaccca taaatgtgat
      481 ttgattcctg gttgattata cggtgtgtct aatgtaagtg gaataccgta tttattagcg
      541 gaatctctcg ctaattcaac atatgccttg tagttctttt caaacgttac tttatcgtgc
      601 gtatgttgca gttcgatttg cacaggacta tttgcattag catatgaacc agcgccatat
      661 tgtacataac caggttgtcc aacttggtaa acgatcccac catcgccaac aatatacgct
      721 gtataggcat tgtaccaaga acgtttcatg tactgcgctt catttcgtcc tgtcgcagtt
      781 tcgtttgctg tttcatgcaa taggatgtat tggttatttg ctacttgaga actaccttcg
      841 tttgcgccca aattgaattc attgttgatc gagtaagcaa aggcgtttat tggcaataaa
      901 aaaagagcta taatagctcc tacaaagatt ttctttttca tttggttcct cctcggtctt
      961 tattttcagt atcatttcgt atttgttgga atacctcttt taacttatct ggcaaaggaa
     1021 ggaataccga aatgttttct aaaaaactaa tcccttcatt tgcaacatag aacataataa
     1081 ctatttctct tagaggtata gaattcccaa cgattttctg tacgtcaacc gcaacggcaa
     1141 tcacaacgaa gattaagact ttcttcaaca atccttcgaa acctatctca ctacttattt
     1201 ctttcaattt ccatgcctta gcaagtccag ttaagaagtc cacacccaca agaaaaatta
     1261 aaacatgtag tatattgtcc atccctccca ataaaccaac aattgtcccg cctatcaccc
     1321 ctgtcattac tgagagtgta tttaaatatt tttccaatat ctatttctcc tttatgcaaa
     1381 gaagcgcact cgtttgagta cgctttttat ttaactttgt gcttaattaa atttcatttc
     1441 cagtaatctg cttatattgg tcttttgtta aacagttcat gtttacatag tcaagtaaat
     1501 cttggtccgt ataacatccc caatcataaa attgttttat attttcaaag cccggaaaac
     1561 tattcattac ttttccctcc attcttaata cttgcgactt ccatcgtcaa ttgagctaac
     1621 atttgttgca ttttttcttg ttcctgtacc gatatcgcca attgttttgt cagtagagca
     1681 tttaattgct tcaactgatc gacatcttca atatcgtcaa ccgctgtgcc actcttctct
     1741 tcttcagtag ctaactcaac ccactgtttt ttatcaaaat caaatcttgg tctccagtta
     1801 ggaactggtg gtttaatctc tgtacagttt tcagggatat tttcttgatt gttcaaaatg
     1861 atttgctcga atccgtaagg ttcaattggt ctatatgctg ccttcatatc gattcacgct
     1921 tttctaaatc gtgtaagtaa ttgcaaaggt ataatccgat ccataacttg agtttcttcg
     1981 ccatttaatg gctccatctg caccaataga taactgagca ctgttcaaag tagaacggtc
     2041 tatcgagcca accagttgct caaaactaat tggtggccga tagccttctg gaattgttag
     2101 tatcgttgaa tcatttccac cactgcgttt tccgtttaaa gccacaaaat atatagaaac
     2161 tgtttttcct tcacgataaa gctttgctga tccggtattc ccgtttgtaa ctgttaatgt
     2221 ggtagtagct gtatcattaa tgcgttcatc gatcttattg tctaattcat ctatagcagt
     2281 cgcattagca ttcgcttttg tttgagcatc cttagctgtg gtgtctactt cattaattga
     2341 agcagtcaac tgcgaattaa tctccgatac tttcccatcg gtataattgt ttgctttacc
     2401 agtaatttca gaaattttaa tatctgtggc caaattatct tcgacatatt ctggtgctag
     2461 atcccaaaca taatcttttg gattgtttga atcacgcata ccagtaccac gatatttata
     2521 ctcactaata ttcggggttc gagtattgcc ttcctctagt tttaaccact taattgtaca
     2581 ttgtcctaca cttgtgcttg gtacttgata aatctgcact tgtggggtag tagggtgtga
     2641 gtcatctgct gctgtaaatg ttttagacca cacattagtt aagccttcta ctggttgtaa
     2701 gtcaccaacc tcccatgcat ctcctgttgc tcgtgtgaaa aatggtctaa aaacctgtgt
     2761 tgctggctta gttccttcaa gtgtgatggt atacttctta ccttttacca ttggtttaat
     2821 gttataggtg ttaataagat agttactatt agtaactggt tgttgtgatt ctggtttaat
     2881 tagattctca cccaaagcca ccttactcaa ataatacggt gcatcaagta gattaggctg
     2941 gtacgg
//
LOCUS       DACGEU010000163         2806 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.169, whole genome shotgun sequence.
ACCESSION   DACGEU010000163 DACGEU010000000
VERSION     DACGEU010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2806)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2806)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2806
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.169"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            84..971
                     /locus_tag="IXR40_002807"
     CDS             84..971
                     /locus_tag="IXR40_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAQ4362589.1"
                     /translation="MQELKTRSARHHRPKRKMVINKKAIAPLIGTSLLVGPMMVTAVP
                     QHVHADEQGSQTVADPQAFIDQIGWSASEVAASNDLYASVMIAQALLESAYGTSGLAS
                     APNYNLFGVKGSYNGQVVYMATKEYVNGQWVTMNEPFRKYSSYWESFQDHANVLRSTS
                     FSTGDYHYAGVWKSNTTSFYDATAYLTGRYATDPNYGAKLNSLINTYNLTRFDTPSTG
                     SATTTTSTTTTTTTTTSTSSSSTTDVNTNNGQTYTVVSGDTLWDIAQKFGMSVDDLMA
                     KNGMSMSSYSLLVGQELNV"
     gene            1111..2037
                     /gene="cysK"
                     /locus_tag="IXR40_002808"
     CDS             1111..2037
                     /gene="cysK"
                     /locus_tag="IXR40_002808"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HAQ4362590.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            2273..2719
                     /locus_tag="IXR40_002809"
     CDS             2273..2719
                     /locus_tag="IXR40_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HAQ4362591.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
BASE COUNT          937 a          453 c          609 g          807 t
ORIGIN      
        1 attaaaagta taatttaatt aattaagttt gttttaagaa gagaactttt tattaagttt
       61 ttttattttg aggaggaatt tgaatgcaag agctgaagac ccgcagtgcc cggcaccata
      121 gacctaaaag aaaaatggtg atcaataaaa aagcgattgc tcctttaatt ggaacgagtc
      181 ttttagttgg gccgatgatg gttacagcgg taccgcaaca tgttcatgca gatgaacaag
      241 gatctcaaac agtcgctgat cctcaagcgt ttatcgatca aatcggctgg tctgcgtcag
      301 aagttgctgc aagtaatgac ttgtatgctt cagtcatgat cgctcaagcg ttgttggaaa
      361 gtgcatatgg cacttccgga ttagctagtg cgccaaatta taatctattc ggtgtgaaag
      421 gaagctataa cggacaggtc gtttatatgg caaccaaaga atatgtaaac ggacaatggg
      481 taacgatgaa tgagccattc cgaaaatatt cttcttattg ggaatccttc caagaccatg
      541 cgaatgttct tcgttcaacc agtttttcca cgggcgatta tcattatgct ggcgtgtgga
      601 aaagcaatac aacaagtttt tatgatgcaa cagcgtactt gacaggtcgt tatgctaccg
      661 atccaaatta tggggccaaa ttgaactcat tgattaatac ttataattta acccgttttg
      721 atacgccatc aacaggttcg gctacaacaa ccacaagtac aacaacaacg actactacga
      781 cgacttcaac gtcatcatct tcaacaacag atgtaaatac aaataatggt cagacatata
      841 cagtcgtgtc aggtgatacg ctatgggata ttgcacaaaa atttggcatg tctgttgatg
      901 atctaatggc gaaaaatggc atgtctatgt ccagttattc tttattagtt ggtcaagaac
      961 taaacgtttg atttagataa aaaggcaaag aaattaccat atatggtata tctttgtctt
     1021 ttttttgcta gtcaaagacg aatcactcgc cataaatgaa cagattgtat tatgataagt
     1081 aagaagagca aagacaagga ggaattgaag atgacagcta tctataactc agtcaccgaa
     1141 ttgattggca aaacgccaat cgtcaaatta aataaaatcg taccagaaga ttcagcagat
     1201 gtttttgtaa agcttgagtt ttttaatcca ggaggaagtg taaaagatcg tattgcttta
     1261 agtatgatag aaaaagcaga acacgatggt ctactgaaac caggtgatac tatcattgaa
     1321 cctacttctg gaaatacagg aatcggattg tcgatggtag gagttgcaaa aggatataaa
     1381 gtaatcatcg tgatgcctga gacgatgagt atcgaaagac gtttattgat gaaagggtac
     1441 ggcgcagagt tgattttgac tcctggtgcg gatggtattt ctggatcaat cagagaagca
     1501 gaacgtttgg caaaagaaaa cggctacttt ttaccattac aatttgaaaa tgaagcaaat
     1561 cctcttgtgc atgagaagac gactggtcct gagatacatc aagcatttgg agtaaatggc
     1621 ttggacgcgt ttgttgcagg tatcggtaca ggaggaacga tcactggcgc tggccgagaa
     1681 ttaaaacgtg tgtatccgaa aatcgaatta atcggggtag aaccagcaga atctgctatt
     1741 ttagaaggga aagaagcggg acctcacaaa atccaaggaa tcggtacagg ttttgttcct
     1801 aaaacactgg atacttctgt gtatgataaa gtcctttcta ttagtggaga cgaagcgatg
     1861 gaaacagcta gagaagttgg gcgaaaagaa gggattttag taggcatctc atctggcgct
     1921 gcaattgctg ccgcgctaaa agtcgcaaaa gaattaggaa aaggcaagaa ggtattagct
     1981 gtggttcccg acaatggtga acgttattta tctacagccc tttaccaaga gatataaggc
     2041 acttggtttt tctccagata ggtttatgta aaaaactttt aaagatgaaa agaacacaca
     2101 aaaatttatg atgagaaaaa ttatttgaat agagacgtag aatagtgaac gcgactgttt
     2161 tacgtctttt ttcattaaaa tacaataaaa ttgaattttc ttttcatgtt aagtggattt
     2221 taaaatgtaa aaatagtatg ataagacgag aataacaacg tggggtgttt acatggaaaa
     2281 taagttagtc gaagaggtta tcgaaaagtt aaaaaaagag aacattcgaa tcacacctca
     2341 acggtacgcg gttttagaat atttgattga acatcattcc catccaacgg ctgatgagat
     2401 ttataaagca cttgaacatc ggtttccaaa tatgagtgtt gcgactgttt acaataacct
     2461 tcgcttattt acttcgattg gatttgttca agaaatgaag tacggcgatg cttctagccg
     2521 atttgatttc agttcaaagc gtcattatca tgtaatttgt gaaaactgcg gtaagattgt
     2581 tgattttcat tacccagggc ttgaagatat agaaatggct gcaagcagac tgactgattt
     2641 tgagattaat gaacatcggt tggaattgta tggactctgt ccggattgta aagagtcagc
     2701 aaaaaaggcg caaatgtaaa aacagtttct acaagtgtta tacctaaaaa aagctagctg
     2761 tgtaaaaaaa acgctagctt ttttattttt ttgtctttta ttcaca
//
LOCUS       DACGEU010000164         2712 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.170, whole genome shotgun sequence.
ACCESSION   DACGEU010000164 DACGEU010000000
VERSION     DACGEU010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2712)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2712)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2712
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.170"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            172..516
                     /locus_tag="IXR40_002810"
     CDS             172..516
                     /locus_tag="IXR40_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HAQ4362592.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVGWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            517..936
                     /locus_tag="IXR40_002811"
     CDS             517..936
                     /locus_tag="IXR40_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HAQ4362593.1"
                     /translation="MTTKHEEIHNGVIFPAGEKNEAYAQVFTGQSYLNMLVNDPEVSV
                     GVGNVIFEPGCRNHWHVHKDGYQILLVTGGEGWYQEEGKPARRLMAGDVVVTHKGIKH
                     WHGATKDSWFEHLAITAGNSEFLEPVTDEVYEGLENQ"
     gene            complement(1028..1378)
                     /locus_tag="IXR40_002812"
     CDS             complement(1028..1378)
                     /locus_tag="IXR40_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362594.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(1344..2675)
                     /locus_tag="IXR40_002813"
     CDS             complement(1344..2675)
                     /locus_tag="IXR40_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HAQ4362595.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGGFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSALSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGLLLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLLGIREIFDSSGKLTT
                     DFIANSGIGATLINIGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
BASE COUNT         1003 a          491 c          523 g          695 t
ORIGIN      
        1 ataaaaaaag cgttagcaac tatgcttaaa aagcatatcg actgaataaa ctaagcattg
       61 gacaggctga aagactacat ttaaaatgaa atgcgaagaa acaatagaaa ataaagttgc
      121 cttagaacca tagttgaatc acctaacagt cgtgaaggga gaataagaga aatggcagaa
      181 aaacaaaccg caggacgaga tcaattagga gattttgcac caaaatttgc agaattgaat
      241 gatgatgttt tatttggaca agtatggtcc agagaagaat tatctgctca tcagcgtagt
      301 atcatcacca tatctgcatt aatttcagga ggaaattttg aacaattgcc agctcatctg
      361 aagattggca agcaaaatgg cattactagt gaagaaatag cagaaatcat tacccattta
      421 gctttttatg taggatggcc aaaagcttgg tcagctttta gtttagcaaa agaaatctat
      481 ttagaagaaa atagcgaaga taagaaagag gcgtaaatga cgacaaaaca cgaagaaata
      541 cacaatggcg tgatttttcc agcaggtgaa aaaaacgaag cttacgctca agtatttacc
      601 gggcaaagct atctgaatat gttagtgaat gatcccgaag tttctgttgg tgtaggtaat
      661 gtaatttttg aaccaggttg tcgcaatcac tggcatgtcc ataaagacgg ctatcaaatc
      721 ttacttgtga ccggaggaga aggctggtat caggaagaag gaaagccagc aagacgatta
      781 atggctggag atgtcgtcgt aacgcacaaa gggattaaac attggcatgg tgcgacaaaa
      841 gacagttggt ttgaacattt ggcgatcact gctggtaatt cagagttttt agaacctgta
      901 acagatgaag tgtatgaagg attggaaaat caataatgtc aagcttgaac agctcctgaa
      961 agtagatttt aatcgaactt tcaggagctg cttttttgat tcagtctttt ataaatagaa
     1021 aatagggtta ataataggaa tgagaagcac gtcgaaagat cttaatattg ataatcggct
     1081 gggcatacat gatttccacg tcatcaatca aactacctaa cagatgataa tcttcccgat
     1141 catgtcgggg attacctaat agttcttgat agtagatttc catactaggg tcccgaggat
     1201 tgttcagcaa atcagcaagt acatctaaat cttctggctg agtttctgcc gtaccctgta
     1261 tctctatgaa aagcccttcc tcagcaaatt ctactccaat acgtatttca gttatttcat
     1321 gggaatataa ataagtaaga agctcatcga tgattctttt tgataattct ttttccaagt
     1381 gtcttttttt cctttctgac agcggtaaag ttatctagta tcggtacaag gatacctgca
     1441 acgaaaccag ttgaaaaacc actgttatat agatttagtc ctccgtgcaa agtgctgacg
     1501 ttatggacaa gagcaatatg tagtacacca gctattacac cgtaaaaact gccgtaaaaa
     1561 ccgcttatgg gcgcgagacc tgtcccaaac acagctgcaa caagcatgcc agtactggtg
     1621 atctcatgaa aagttccaaa caaagaagca ataaatattc cgactagtat cggaaaactg
     1681 ttttttaaat gacaaccaaa agcactgaaa cccaccgcag ataaaatagc accgatgaca
     1741 ggtccattta actgaccgcc aaccagcaaa acataagaag acagcatcag accaactaag
     1801 cctatgttga tcaaagtagc accaatacca gaattagcaa tgaaatcagt tgtcaatttt
     1861 ccagatgaat cgaaaatttc tcgaatcccc aaaagccgaa aggaattata atagaaacca
     1921 attccgactg tcagcgaaaa aaagccaaaa ataatccaaa tgagaggaaa gtgatattca
     1981 ttgaaaacca atgtattttc gacgattgaa tagctgaata acctcaaaac agcagtaaaa
     2041 gtcatcgcaa tcaacccaga ggtgaatcca atattataaa gtgtgaatcc acgatggaaa
     2101 actaaagttt gagcagctaa gggcggaaga agtagaccaa ttgctatgcc agctaaattc
     2161 cccaataaaa tacctatcag taaaggaaaa cgcataccaa aagtgatata actaacgacc
     2221 ggtgataatg cgctaccaaa cagtccgatc atgatgtact gagaaaaagg tttattgaca
     2281 aatacagcgt atagatacac acctaaaatg attgagatag aattataaag gtttttgcca
     2341 aaaaaagaga aaccggtaac tgttagaatc gaagcaaata agggaccgtt taaaatcacc
     2401 ttgtgccgat aagctaaaag cacagaaagt aaggtcaaaa tccctacatt tatgaatgcg
     2461 cttccgaaac cgcctaaagc aaaataatct gtcaaaagat tgcttggcga ggtaagaata
     2521 gttagcaatc cactccaatt atcagtagga gtattagaaa gcaagccaat aaaaagaaaa
     2581 aaaacacctg taaaaccaag ataaaaatac tttcttttct gtgaaacgat tcgtttttga
     2641 ggatgaatat aaataacgtc agtttcgttt tccattacac accttctttt tcattttctt
     2701 taactataac tt
//
LOCUS       DACGEU010000165         2650 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.171, whole genome shotgun sequence.
ACCESSION   DACGEU010000165 DACGEU010000000
VERSION     DACGEU010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2650)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2650)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2650
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.171"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(195..560)
                     /locus_tag="IXR40_002814"
     CDS             complement(195..560)
                     /locus_tag="IXR40_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362596.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            768..1250
                     /locus_tag="IXR40_002815"
     CDS             768..1250
                     /locus_tag="IXR40_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362597.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     FVVSRNFPALIVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSTFSLLPRLIIGP
                     NGLSESGLKDLAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            1447..2337
                     /gene="pstS"
                     /locus_tag="IXR40_002816"
     CDS             1447..2337
                     /gene="pstS"
                     /locus_tag="IXR40_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HAQ4362598.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
BASE COUNT          904 a          432 c          525 g          789 t
ORIGIN      
        1 atgtttccac ctcaaattca atatctatta ttggaatcat tattgctgca attattacac
       61 aactgttttt agtgtttgga gagaagaaaa gaagtaaaaa atagaaaaac tagtgatagt
      121 tttggtgata taagaaaaac atatatgtat aaaaagaaga aagtagcttc tctttgtaca
      181 tatatggttt gtttttatgg atgccgagct tttttataag ataaggctac cgcccataac
      241 gacccaagga tttgtggaac taagtaaata cctgcaagaa gcaagatcag ctgggtcggt
      301 tttaaaggat gatagaagta acgccattca gtaaaattgg cgcaaaataa ataggaagtg
      361 acagtagata taatattggc aatgaataaa gatataatac gcctgttcct ttgaaaataa
      421 tatccagcaa aaagagataa aaatatcaat gtgatgaacc cgcttacgga atgataacga
      481 aaatcaagca gtaaggcgaa atgcacataa ggaacaaaag ataaaagcaa cggaaggttt
      541 ttccagcaag tttttatcat ctttcatcac cacctaacaa gtgttattat tttgttagtt
      601 ttattgtaaa ttgaatcctg caataatcaa ttactttttc attatttcta gattaaatga
      661 ataaactctc atgccattat ctctaaaaaa aaagtttttc cccctaattt ttttagatag
      721 aaaattgtat agtatgatga gagaaaaagt agtttggggg aacgttaatg agaagaaaag
      781 cagtaatcga tcggctttat ttattttttt ggttttttcc tatcgttttg ctacctttta
      841 catgggtaaa tgctgttgta caaggtgcgg agatattagg cctgatccaa ggaagcggat
      901 ttgtggtttc taggaatttt ccagctttga ttgttttcta tttagtgata agtgtaggtc
      961 tcttattacc aaaatctctg atcaatcact acaattggca gctgctttac ttttcttgct
     1021 tattagtatt tacatctacg ttttctttgc tgcctcgctt gattatcggc cctaatggtt
     1081 tgagcgagag tggattgaag gatttagctt attcctccat gtatttcttg acgatcaaac
     1141 catggttcta tttagtaatt gcctcattta ttcttgcaac atttttttac ttctggacag
     1201 aaatcaggat aaaaagtgaa cgatctgtat ctataaaaaa taactattga tggtggatca
     1261 tcagtaaaaa aacatatgag ctgcgtaaaa tgcatgtttc tcatatgctt tttttattat
     1321 tatgtaaaga atgcgaaaaa cgtttacatg atttttacat aacttaacta tatttttaca
     1381 gcaaccatac gagggattta cagtcgactg ataaacttta gttgtaaata agaaaggagc
     1441 aataaaatga aaaaagtatt gtttactcta ggtatgatgg gaattctttt agccggatgc
     1501 ggctcaggat caggaaatac agatggctct gccacacaaa ataattcaag tgactcaaat
     1561 gaacaagtaa aaatcgttgc ggtaggttcg acagcattac agccgttagt cgatgcagca
     1621 caagaaagct ttgtacaaga aaatccaaat tatcaaatct ctgtacaagg aggaggaagc
     1681 ggaactggtt tgagccaagt cgaagctgga gcagttacta tcggaaactc tgatgtattt
     1741 gcagaagaaa gagacggagt tgatgcttca aaattagtgg atcataaagt agcagtggtc
     1801 gggatggcac caatcgtcaa taaagataca gatgtcaaag atatcaccaa acaggaattg
     1861 attgatatct ttacaggaaa aatcactaac tggaaggaag ttggcgggaa agatcaaaaa
     1921 atcaacgtcg tgaaccgtgc aaacggcagc ggtacccgcg cgacattcga aaaatgggga
     1981 ctggatggtg ctacccctgt gcagtcccaa gaacaagatt catcaggaac agttcggcag
     2041 ctggtaagtc aaacaccagg agcaatcagc tatttagctt tctcatatct cgatgattcc
     2101 acacaagcac taagtatcga cggtgtagaa ccaaaagaag agaatgtagc agataacagc
     2161 tggggaatct ggtcatatga acatatgtac acgaacggaa aaccttcccc tgaagtccaa
     2221 aaattcttag actacatgat gacagaagaa atccaagaag gacctgtcaa agaattgggc
     2281 tatttaccaa tcacaatgat ggaagtagaa cgtgatcacg aaggaaatat caaataacta
     2341 gcagataaac atgccacggt agtcgttact attaaggaaa aatcaactat gtttccccac
     2401 atatacattt ttcctttaat tgtgaaaaat agttcctcat attttgccgt tttttgagct
     2461 aataccgagg gtcagctgat tgaacaccgt ttattcgaaa aaaagagcta cgacatagaa
     2521 ctgtcgtaac tttttttggc tcttcgtcaa atcgtgttgg tgaagacaaa tttgaataaa
     2581 acttagaccg atatgcggcg cgttctgtgc gccgcatatt tttttagttt tcaaagatca
     2641 gaccttgttg
//
LOCUS       DACGEU010000166         2540 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.172, whole genome shotgun sequence.
ACCESSION   DACGEU010000166 DACGEU010000000
VERSION     DACGEU010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2540)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2540)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2540
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.172"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            407..1516
                     /gene="pdhA"
                     /locus_tag="IXR40_002817"
     CDS             407..1516
                     /gene="pdhA"
                     /locus_tag="IXR40_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HAQ4362599.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            1519..2496
                     /locus_tag="IXR40_002818"
     CDS             1519..2496
                     /locus_tag="IXR40_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HAQ4362600.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
BASE COUNT          846 a          471 c          532 g          691 t
ORIGIN      
        1 tgtttctttt ttttcggaaa aagaatacga tataaagaaa ctaagaaaaa accattattt
       61 gtacgtccgt tcacgatgtg taaataaaat aaatgtttgc aacaaaactg tataacacca
      121 acgtttttaa atagaaacag atggttgtaa gtttgattag aaaatagaaa aaatgcagat
      181 gaaatataaa acgctttcct tattgtgatt ttattcacta atgctgttaa tatgcggatt
      241 ggcataattt cctttcatcg tgaaaatttg tgcttttagc ttgtatttct cataaatcca
      301 tgataattta ttaatgaaga cggttaaata gtgatacagt tttattcact gtttcaatcg
      361 cagaatgaag agattttctt atagatgaga gaggaatgtg tgacaaatgg caaacaaaaa
      421 agcaccgatc gacttccaag cactgctaga tgaagtcaat gcagatttcc cagtatatca
      481 agcacttgat caagatggaa acgtagttaa caaagattta gtacctgatt tatccgatga
      541 tgaactcgtt gaattaatga ctcatatggt atggtctcgt gtattagacc aacgttcaac
      601 agcgctgaac cgccaaggac gcctaggctt ttttgcacca actgctggac aagaggcaag
      661 tcagctggct agtgcttacg catttgataa agaagatgtt cttcttccag gttatcggga
      721 tgtacctcaa ctagtaaaac atggtttacc tttatctcaa gcttttttat ggtctcgagg
      781 acatgctgca ggtaattctt atccggaaga attgaaagct ctaccaccac aaattatcat
      841 cggtgcacaa tatgtacaag cagccggtgt tgcattaggt ttgaagaaac gaaacaagaa
      901 aaatgtcgtc ttcacttata ctggtgatgg cggttcatca caaggtgatt tttacgaagc
      961 aatcaatttc gctggcgctt accatgcaaa tgccgtattt tatatccaaa acaacgggta
     1021 tgcgatctct acacctcgtg aaaaacaaac tgcagcaaaa acacttgcac aaaaagctgt
     1081 cgcagctggg attcctggta ttcaagtcga tggaatggat ccgcttgcag tatatactgt
     1141 atctaaaatg gcacgggaat gggcgatcag tggaaatgga ccagtcctaa tcgaaacact
     1201 gacttatcgt tatggaccac atacactatc tggtgacgat ccaacccgct accgtacaaa
     1261 agacacagat gacgattggc agaaaaaaga tccattgatc cgcttccgta aatatttgac
     1321 ggaaaaagga ctttggtctg aagaaaaaga agaacaagtc atcgaagcaa ctaaagaaga
     1381 aatcaaagca gctattgctg aagccgacaa agtaccaaaa caaaaggttt cagatttctt
     1441 gaaaaacatg ttcgaagtat ctccacaatc aatcaaagaa caaattgcaa tttatgaagc
     1501 gaaggagtcg aaataatcat ggcacaaaaa acaatgatcc aagcaatcac agatgcctta
     1561 gcacttgaac tagaaaatga cgagaatgtc gttgtttttg gtgaagatgt tgggaaaaac
     1621 ggaggagttt tccgggcaac tgaaggattg caggaaaagt tcggagaaga ccgagtattc
     1681 gatactcctt tagctgaatc tggaatcgca ggattgagtt tcggtcttgc gttagaagga
     1741 tttcgtccag ttcctgaaat ccaattcttt ggttttattt tcgaagcaat ggacgaagta
     1801 gtagctcaaa tggctcgtac aagatatcga atgagcggca ctagaaatct acccatcaca
     1861 attcgttcgc catttggtgg cggtgttcat acaccagaat tgcattcgga taatttagaa
     1921 ggtttgatcg ctcagtctcc tggtattcga gtagtgattc cttccaaccc ttatgatgca
     1981 aaaggactat tgatttcttc tattagaagt aacgatccgg ttgttttcct agaacacatg
     2041 aaactatatc gctcattccg agaagaagtg ccggatgaag cttacgaagt tcctttggat
     2101 aaagcagcag ttactcgtga gggaacagat gtatctatta tcacatacgg agcaatggtg
     2161 cgtgaagcaa tcaaagcagc agacaatctt gcaaaagaaa atatatctgt tgaaatcatt
     2221 gatcttcgta cagttgcgcc attagatgta gaaacgatca ttcaatccgt ggaaaaaact
     2281 ggtcgcgtag ttgttgtcca agaagcacaa cgacaagcgg gcgttgccgc gcaagtagtt
     2341 tctgagatct cagaacgcgc tatcctttca ttagaagccc caatcggacg agtttctgca
     2401 cctgatacag tcttcccatt tggacaagca gaaaatgtct ggttgccaaa tgcaaaagat
     2461 atcgaagaca aagtaaaaga aatcgcggaa ttttaagaaa agaagggacg aaacaaagtc
     2521 atggcttatc aatttaaatt
//
LOCUS       DACGEU010000167         2467 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.173, whole genome shotgun sequence.
ACCESSION   DACGEU010000167 DACGEU010000000
VERSION     DACGEU010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2467)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2467)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2467
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.173"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            81..353
                     /locus_tag="IXR40_002819"
     CDS             81..353
                     /locus_tag="IXR40_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362601.1"
                     /translation="MNLIATYYRTLEELKKQNGQWFFQALLCLEAGVKPNTIKPSEYQ
                     ALELTYGKFVETKKAKTVSSEWLDYLENVNKYGACYIMKKEDNENE"
     gene            346..1041
                     /locus_tag="IXR40_002820"
     CDS             346..1041
                     /locus_tag="IXR40_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362602.1"
                     /translation="MNKVIYQLTTEDVSHFLTNKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYLESETSQTKVTVSNNYLDVYKRRPDTLKKGAELLRLETEKYIMNVYLERS
                     ELVENFVSYTICRKHYYSESEYYSIFESMELMEELNSKDATVDDYYLVFTKFLTCGTE
                     SIVLMGMDYELAVPEVFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNELDRK
                     RMPYQRFERKKGQ"
     gene            1421..1600
                     /locus_tag="IXR40_002821"
                     /pseudo
     CDS             1421..1600
                     /locus_tag="IXR40_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1662..1846
                     /locus_tag="IXR40_002822"
                     /pseudo
     CDS             1662..1846
                     /locus_tag="IXR40_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003027804.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module toxin, HicA family"
     gene            1880..2311
                     /locus_tag="IXR40_002823"
     CDS             1880..2311
                     /locus_tag="IXR40_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HicB family protein"
                     /protein_id="HAQ4362603.1"
                     /translation="MLSEPLAKTYPAIFSPEEGGGYFIEFPDVQGAYTGINEDDISYG
                     IAMAQEVLGMVLADYIEHEDLLPEPTPINKISVEDDSFTTLIRVDVAKYLKDTELVKK
                     TLTIPQWADKLGKRAGINFSVLLTESIADKADNILRSGRNN"
BASE COUNT          877 a          387 c          514 g          689 t
ORIGIN      
        1 atgagacacg tgtaccaaaa aaacattata aggaaagatt gtcggtagct gtggaagaaa
       61 tgattgaatc gggtgtcgaa atgaatctca ttgcgaccta ctatcgaacg cttgaagaac
      121 tgaaaaagca aaatggacaa tggtttttcc aagccttact atgcttggaa gcaggcgtca
      181 agccaaacac tatcaaacct tctgaatacc aagctttaga actaacgtat gggaaatttg
      241 tcgaaacgaa aaaagccaag actgtttcaa gtgaatggtt ggactactta gaaaatgtca
      301 acaagtatgg cgcatgttac atcatgaaaa aggaggacaa cgaaaatgaa taaggtgatt
      361 tatcaactaa caacggaaga tgtgtcacac tttttaacaa acaaagaaca tttgaatgaa
      421 gtaatcagac ggattcaaaa agactttagt tgtatggaag aaatgaagta ctttattcaa
      481 agagtcgaag aacaattgta tttggaaagt gaaacgagtc aaacgaaggt tacagtcagc
      541 aataattatt tagacgtgta taaacgtcgt cctgacacat taaaaaaagg agcggagctt
      601 ctacgactag aaacagaaaa atatatcatg aatgtttacc tagaaaggag tgaactggtc
      661 gaaaactttg tcagctacac gatttgcagg aaacactatt actcagaatc agaatattat
      721 tcaatttttg agagcatgga attaatggaa gagctaaaca gcaaagatgc gacggtagac
      781 gattattacc ttgtatttac taaatttttg acgtgtggga cggaatctat cgtgttaatg
      841 ggaatggatt atgaactcgc tgtacccgaa gtatttttga gggaatatgt agaagaagta
      901 gataacccag gcgacgactg gtacacgact ttaactgatt ttttagatac ctacacttac
      961 gacgatacag aagaaatcca aaatgaactt gaccgtaaac gaatgccata tcaacgattt
     1021 gaaaggaaaa aaggtcaata accatttata ccgaaaagtg agaatgtgtg aaataagaac
     1081 aaaaaccttg aaattaaggg aatggttctt atttcgcacc aatcgctcca accgcccccg
     1141 ccgcttaggt ggtgcgaaat aagcgagcaa agcccgaaaa cctaagagaa agaaggagat
     1201 ttatatgaac aaaattattc ccttattatt agtcctattt gttggagaaa tacttatgcg
     1261 acttagtgca gctgtacatt taaacctcgc agtatttttg gtaatactaa tgttttgttt
     1321 gatcttttgg cgatttgtat tagccctcgt aagtctacta ttcaagatga ttgcagccat
     1381 atttttcata ggattatttc gatgaaagga gagagtacca atgccaattg caataggaaa
     1441 taaacggtta cccgtgacgt tggatgaaaa gagacaaaaa gaattgcagt aaccaaagca
     1501 gaagtacggc aaaagtgaat ccaggattat gtgtattgcg ttagatttat tgattgcgca
     1561 agaaaaagca ggatttgaca taccagcact caaaaagtga tcgcactttg cgcacgtgtt
     1621 aatacgtgtt ataattattt tgtaaggagg tatagtgcac aatgccactt acgggaaaag
     1681 aaatgcttaa gttattgaaa aaaatggctg ggttgagcga aggcaagagg gatttcatca
     1741 tcatctttat aaggatggtg ttagaatcac tgttcctgtt catgccaatc aagatcttgg
     1801 ccgaggactt gagcgaaaaa ttttaaagga tgcgggattg aaataatctc gcattcgatt
     1861 aaagaaagga ttgactgaaa tgttaagtga gcctttagca aaaacctatc ctgctatttt
     1921 tagcccagaa gaaggtggtg ggtactttat tgaatttcct gatgttcaag gtgcttacac
     1981 aggaattaac gaagacgata tatcttatgg aattgctatg gcacaagagg tgttaggtat
     2041 ggttttagca gattatattg agcatgaaga tctacttcca gaaccaacac caatcaataa
     2101 gatttctgtt gaagatgatt cttttactac tttaattcgt gtagatgttg ccaaatattt
     2161 gaaagacaca gaacttgtca aaaaaacctt aacaattcct caatgggcgg ataagctagg
     2221 caaaagggct ggcataaatt tttcagtcct tctaacagaa tcaattgcag ataaagcaga
     2281 taacattctt cgttctggaa gaaataatta gaactcaaaa gggtcagaaa cttaaaaatc
     2341 tttggcttct ttttttacta caaagatggc ttctttaaat tatttgcctg attgatttaa
     2401 aaaaattgcg caaagactac gagctaatta agttgctcgt ggtctttttt tatgaaaact
     2461 ttttaga
//
LOCUS       DACGEU010000168         2409 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.174, whole genome shotgun sequence.
ACCESSION   DACGEU010000168 DACGEU010000000
VERSION     DACGEU010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2409)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2409)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2409
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.174"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(4..249)
                     /locus_tag="IXR40_002824"
     CDS             complement(4..249)
                     /locus_tag="IXR40_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362604.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            complement(266..1117)
                     /locus_tag="IXR40_002825"
     CDS             complement(266..1117)
                     /locus_tag="IXR40_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HAQ4362605.1"
                     /translation="MNSLTSTYRLSNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQTTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            1283..2287
                     /locus_tag="IXR40_002826"
     CDS             1283..2287
                     /locus_tag="IXR40_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HAQ4362606.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
BASE COUNT          774 a          406 c          485 g          744 t
ORIGIN      
        1 tttctatttt ttcggtatca aggcaaaaac aggtagttca ggtgaataaa tgacttcatg
       61 ttcgtgccag ggtttgacca ttagcgaatg atcgaaccgt tttttcagtt cttcgatgat
      121 ttgatcatgt gtccagtttc ttgcaggaaa atgttggatt ttctctgcat cgatcaaaaa
      181 gacaaaatcg gaatgaaaag tctgggtaac ttcttccgag agagaattca agcgttcgat
      241 tggatccata aaatcacctt tcgacttaaa attgggtagt atctgggtct tttgctttgc
      301 cgactacacc atctaactga tcgatttgtt tcatttcttc ttctgttaat tcaaaatcaa
      361 ataattcagt attttctttg attctgcttg gtgtcactga cttaggaaga ggaaggaatt
      421 cgtgttgcag cgaccaacgc aaagcaactt gtgcaatcgt cttgtcatgt gcttcagcga
      481 tttgtttcat ttcaggcaca tcgaagattt taccagtgcc taatggacta tatgcttcga
      541 ggatcatatc atgttttttt gcatactcaa ctacagttgt ctgtaattcg cctggtgcaa
      601 ggaaaacttg attgaccatc ggcataattt ttgctgtttt tgctagtgta tctagatggt
      661 ggggtaagaa attgctcaca ccgattgctt tgattttacc tgcttcatac agttcttcaa
      721 atgctcgcca tgtatctgca tttgcttgtt cccaattatc acgaaaagca acagggtttg
      781 gccagtggat caaaaacaga tctaaataat ctgtttggag cttcttcaat gattcttcaa
      841 aagaagacat cacaagttca tagctgtggt ttgcattcca taattttgtt gtcaagaata
      901 tctcttctct aggaattcca ctttccttaa tcgcttggcc gacgctttct tcattcttgt
      961 atccttgggc agtatcgata tggcgataac ctgcagccag cgcttcttta acagaggaaa
     1021 cagcgacatc cccatcaggt gtttgccatg tgccgaatcc tactaccggg atttcgtaac
     1081 catttgatag acgataagtg cttgttaatg aattcatact ttcagctcct tttttattcg
     1141 ttcaactata agtgtagcgc atttttcgaa aaaaagaatc cattttgttt ctactcttga
     1201 aatttttgtt taaaagaaaa tgattttgat tctggtattt ttgatttttt ttccgtaaac
     1261 taagacagaa gggaatgaga aaatggatat ctatttaaaa aaagcaattc tgcatattat
     1321 tgacagagaa actggttctc cagtcttttc acaaaaagag ctggatctga caaaagaata
     1381 tattcgtgat tttcttcaaa agaagatcca aaaaatctct tctgctcaaa caaaaactgg
     1441 acaactagca gaagaaagca tgatcgttga atcacttaaa atcgctcaag aaaattttgt
     1501 ggaagcaagt gaagcaatcg ttcagcggtg gttcgatatc taccaagaaa gtgaagaagc
     1561 acctagtgca gatgtatttg ttgtcttgta tgaattagat acagtgatgt acttatcttt
     1621 attgaaagtc aattatcgtg aggcttacac tcactttgtt gaagcagacg aagcagggat
     1681 cgacaaccgc ttgattttga atcgagcaat tctaggggcg aaaacacaaa aagcagatga
     1741 agcattcgct gtgaatttga ctgattggac ctacgaatta attgaaaaaa aatatgagtt
     1801 ttctggcaaa aaagagcttt atttttctgg aagagtgatc gaaagtgttc ctgcaccttc
     1861 tttagaagaa aatgtaaaag tgatccaaaa agtagccaag catcttggaa aaaaatttga
     1921 gacagaagaa tttgatatca tggctgattt gaaagaagct gtctatgata cgatagaaga
     1981 aaaaggtcgg ttggatcatg agatgattgc ggaaaaagtc ttcaaggaaa acatcacggc
     2041 aaaaatggct tttaaagaag aagtacaaga gcaaggattt gtcccagaag cacctcctgt
     2101 aaaagaagta caagaaattt ctgagaaaaa atttggaaaa caaaaattca agctatcaaa
     2161 cgggatcgaa ctgatcgtac cagtagatgt atatcgcaac ccagatttga ttgaatttgt
     2221 gaataatccg gatggtacga tatccgtgat gatcaaaaat gtggatgaag tattgaatcg
     2281 tttataaaaa tgactagaat attaggtgtt caagtaccag tgatcagtta aatgaattgt
     2341 gtcaagagaa ggatcggaaa agacgaatat aacaaaaaaa gagcgtgaga caaaagtaaa
     2401 gaacacttt
//
LOCUS       DACGEU010000169         2400 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.175, whole genome shotgun sequence.
ACCESSION   DACGEU010000169 DACGEU010000000
VERSION     DACGEU010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2400
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.175"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            207..2069
                     /locus_tag="IXR40_002827"
     CDS             207..2069
                     /locus_tag="IXR40_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAQ4362607.1"
                     /translation="MQQLTKRERQLLIYLVEMSEPVTIKKLAEKENVSVRTIKYDLDD
                     IREWLNERKQVLYSKRSQGIWMNISSSDRIKLKSELMDVNRFEIFADQSLRIKRLLIM
                     LLVTKEAITGMKMANALDVSKDTIMNDLDVLENNFLKEGLTLNRQARKGFWIIGEERL
                     VRLTIEEILQKEFTDYDIYKLMSLLLNGGETEYFEMYSATATPIQEVFNQVIIRMRHL
                     LEFENLEKLNYAELLNILIRVTIATVRLRKEATIGRYQLVAEQELDKNDLSYRVMQQV
                     FDYYQLPLFEDEYHYIYSDTFDTIHQQDVMKLVENVIYKVSKAINHSFYQDPQLLTNL
                     YAHLSMRLSRKKKFVNEYNPFKEDIKQKYPELFDAIKQAVRQEISEQNILINDSFVAY
                     IALHFLVSYEREEDLRSVRAVYICSTGLGVTSLIKQKINEELNNITIVAFASVLNAQE
                     MIATKDPDLVISIFPINGIDRPFIKVHPLPTEQDLKKIQQIIKKILASSNQQERHNLN
                     LRETSINKDTLEDFSKELILKAYTIYERLLVILEAELIQEYREAFLLHVFLMVHRITF
                     DQQYMAEGRQVDQIILDKGTLVGKIEAVFAENNLGINQSEISALFSYIKEGASS"
     gene            2069..>2400
                     /locus_tag="IXR40_002828"
     CDS             2069..>2400
                     /locus_tag="IXR40_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAQ4362608.1"
                     /translation="MKMSDEALKIIEESQNREKLKQVIDLIEERLVEHAIVPTELQWT
                     ILINHLNEMLKRSQRKETIPVVDRDLFKEVSKEAITISDEIVRSIGNLTDDEIYVLSI
                     HFETAKNN"
BASE COUNT          866 a          353 c          466 g          715 t
ORIGIN      
        1 aaaaatttga aaaagcgttt gattatttat attacgactt agtgcaataa aaaacgcttt
       61 ttaacagtac atgtagtcgt ctttataata gataaactct gtaatattag ttaaaaagct
      121 ataagttgca cttagttaag tgcaaacatt tcatattgtc gttagtttag aaaacgctta
      181 tattagcaat gtaaggagag atgataatgc agcagctaac aaaaagagaa aggcagcttt
      241 tgatttactt ggtggaaatg tctgaaccgg taacaatcaa aaagttggct gaaaaagaaa
      301 atgttagtgt tcggacgata aaatacgatc tagatgatat aagagagtgg ctgaatgagc
      361 ggaagcaagt cctatatagc aaacgtagtc agggaatttg gatgaatatt agtagctctg
      421 atcgaatcaa attaaaaagc gaattgatgg atgttaatcg ttttgaaata tttgcagatc
      481 aaagtctccg aatcaaacgt ttactaatta tgcttttagt aacaaaagaa gctattactg
      541 gaatgaaaat ggccaacgca ttagatgtca gcaaagatac gatcatgaat gatttagatg
      601 tgctggaaaa taattttctt aaggaaggat tgaccttgaa tcgtcaggcg cgaaagggtt
      661 tttggatcat aggagaagaa cgtctagttc gattaacgat tgaagagatt cttcaaaaag
      721 agttcacgga ttatgacatt tataaattaa tgtcattgtt attgaatggc ggtgagactg
      781 aatactttga aatgtattct gctactgcta cacctatcca agaggtattt aatcaagtaa
      841 tcattcgaat gcgacactta ctggaatttg aaaatctaga gaaactgaat tacgcggaat
      901 tactaaatat tctgattcga gtgacaattg ctaccgttcg cttacgcaaa gaggctacga
      961 ttggtcgtta tcaattggtt gctgaacaag aattagacaa aaacgatctt tcttatcgcg
     1021 tcatgcagca ggtctttgat tattatcagt tgccactgtt cgaggatgaa tatcattata
     1081 tctatagtga tacattcgac acgattcacc agcaagacgt catgaaacta gttgagaatg
     1141 tgatttataa agtaagtaaa gcaatcaacc attcttttta tcaagatcca caattgttga
     1201 cgaatctgta tgctcattta tccatgcgat tatcgagaaa gaaaaaattt gtcaatgaat
     1261 ataatccttt taaagaagat atcaagcaga aatacccgga attatttgat gcgatcaagc
     1321 aagcagttcg acaagaaata agtgaacaaa atattctgat caatgattct ttcgtggcat
     1381 atattgcctt acactttttg gtttcctacg aaagagaaga agatctacga agcgttagag
     1441 ccgtctacat ttgttcaaca gggttgggtg tgactagtct gatcaagcaa aagatcaatg
     1501 aagaattaaa taatatcact atcgtggcat ttgcttcagt attgaatgcg caagaaatga
     1561 ttgctaccaa agatcctgat ttggtgatta gtatttttcc aattaatggc atcgatcgtc
     1621 ctttcatcaa agtccatcca ttacccactg aacaggactt gaaaaaaatt caacaaataa
     1681 taaaaaaaat acttgcttct tccaatcagc aggaaaggca taacttgaat cttagagaaa
     1741 cgtccatcaa taaagatact ttagaagact ttagcaagga attgattttg aaagcttata
     1801 cgatttatga acgtttactt gtcattttgg aagcagaatt gatccaagaa tatcgagaag
     1861 cttttttgct tcatgtattc ttaatggttc atcgtatcac atttgatcaa caatatatgg
     1921 cagaaggtcg tcaagtagac cagattattt tagacaaagg aacactggta ggaaaaatcg
     1981 aagcagtttt tgcagaaaat aatttaggaa tcaatcagtc agaaatcagt gcattattct
     2041 catatataaa agaaggagcg tcaagttagt gaaaatgtca gacgaggctt taaaaattat
     2101 cgaggaaagt caaaatcggg aaaagttaaa acaagtgatt gatctaattg aagagcgatt
     2161 agtagaacat gctattgtac caaccgagtt gcagtggacc attctaatta atcacttgaa
     2221 tgagatgctg aaacgttctc aaagaaagga aacgattccc gtagtcgatc gggatttgtt
     2281 caaagaagta tccaaagaag ccataactat ttctgatgaa atagttagaa gtatcggtaa
     2341 tttaaccgat gatgaaatat atgttttgtc gattcatttt gaaacagcaa aaaataatta
//
LOCUS       DACGEU010000170         2387 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.176, whole genome shotgun sequence.
ACCESSION   DACGEU010000170 DACGEU010000000
VERSION     DACGEU010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2387)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2387)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2387
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.176"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(365..1657)
                     /locus_tag="IXR40_002829"
     CDS             complement(365..1657)
                     /locus_tag="IXR40_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAQ4362609.1"
                     /translation="MARKKRNPDAEKLAESILNAYQPESVDDMQDALKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKEHDNRRNGYGTKTLKTSFGEVAIDVPRDREASFEPELIP
                     KRKRDVSDIEGKVLSMYARGMSQRDIAATVEAIYGFDISHEMISDITDAVLPELEEWQ
                     ARPLAKCYAFLFVDCMYVTLRENYEAKEYAVYTILGYDLKGNKEILGLWLNQTESKNR
                     WMQVFDELKARGVEDVFFISMDGVSGLEEGAKAIFPSVIVQRCIVHLVRNALRYIPSK
                     DYKEVCRDMKKFYGASSLNAAHAAFDSFQNRWSHYSGAVDVWKRNFAHVEQLFDYGSA
                     IRKIMYTTNAVESVHSSFRKVTKKGAFSNENALLKLLYLRTKELHAKWSGGRIQNWAM
                     VLNQLMINETFSSRMKSMRFTFRNNGRFIQLCVRSKFI"
     gene            complement(1931..2191)
                     /locus_tag="IXR40_002830"
     CDS             complement(1931..2191)
                     /locus_tag="IXR40_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362610.1"
                     /translation="MKKIDLINMIGMLIGILVNIVIFTDWLGVLFSNLIPILIIGICG
                     IILSILELFESRNTMNRIFACIILIVNLLPMVYFTFLYFALG"
BASE COUNT          805 a          445 c          363 g          774 t
ORIGIN      
        1 tatgggctac tctgtgatac ttattagcca ttaaactatt ttacccacat agcatatatt
       61 ttgaaatcgt tcattccgta aattcaacta aatatgccta aaaaaataaa aaatctaaga
      121 tagaataaga tttattcagt cttagatgga tttatagcaa ctttttcgta acaactttaa
      181 aaaatacgaa aagaaagagc tgttttactc tgactacgtt gctaaattgt cgtttaatca
      241 ttcatttaaa ccaaatcttt ttttatagaa ttcgttttaa tcctcctgaa tccaaaaact
      301 atgaaaaccg taattaaata gttaagagtt tttaaccacc ataattctct cggctatttt
      361 gaaatcagat aaattttgat cggacacata gttgaataaa cctaccgttg ttacggaagg
      421 taaatcgcat acttttcatt ctagaggaga aggtctcgtt gatcattaac tgattaagca
      481 ccatagccca gttttgaatt cgaccacctg accacttcgc gtgtaattct ttcgtgcgta
      541 aataaagtag ttttaggagt gcattctcat tagagaacgc tccttttttt gtgacttttc
      601 tgaagctgga gtggacactt tcaaccgcat tggtagtgta cataattttt cgaatggcac
      661 taccataatc aaatagttgt tcaacatgtg caaagttccg tttccagaca tctacagcac
      721 cagaataatg agaccaccga ttttgaaaac tgtcaaaagc agcatgtgca gcgtttagag
      781 aagaagcacc gtagaacttt ttcatatctc ggcagacttc cttatagtcc ttacttggaa
      841 tatagcgcaa tgcatttcga acaagatgaa caatacagcg ctgaacaatt accgatggaa
      901 agatcgcttt tgcgccttct tcgaggccag aaacaccgtc catcgaaatg aaaaagacat
      961 cttcgacacc acgtgctttc agttcatcaa atacttgcat ccagcgattt ttagattctg
     1021 tttgatttaa ccataatcct aaaatctcct tatttccttt gagatcatag ccaagaatgg
     1081 tgtatacagc atattctttg gcttcataat tttctcgtaa agtaacatac atacaatcaa
     1141 cgaatagaaa ggcataacac tttgctaggg ggcgggcttg ccattcttcc aattcaggaa
     1201 ggacagcgtc agtgatatct gaaatcattt catgggaaat atcaaagcca taaatagctt
     1261 cgacggttgc ggcaatatct cgttgactca ttcctcgtgc atacatggaa agaaccttcc
     1321 cttcgatgtc ggagacatct cgttttctct taggaattaa ctctggttca aaggaagctt
     1381 cccggtctct aggaacatca atagctactt caccaaaact ggttttaagc gttttagttc
     1441 catagccatt tcgacggtta tcgtgttcct taggctcttt agaatgggca tcataaccta
     1501 aatgattatt caattctcct tgaagcattt tttcaaaaag gggcccaaac acatctttca
     1561 aagcatcttg catgtcatcg acagattcag gttgataggc attcagaatg gattcagcta
     1621 acttttcggc atcaggattt cttttctttc tagccatcgt gtaatcacct cttgatctta
     1681 ttgtagaaaa agaaaaaccg cgaagcaacc acctgcctag gattaatggt tacttacacg
     1741 gtttatatta cactctcatc attaaaaaag tatctttcga tattactaaa caatgaaatt
     1801 atctatttga aatttaaatc tgataatata ttgagtgttc caatgagggc tttgatccta
     1861 ttatccatat ctttttcagt tttaatattg atacacatta taagaaaaag aaacttttgg
     1921 ttaatttatt tcatcccagt gcaaaatata aaaaagtaaa atagaccata ggcaatagat
     1981 taacaattaa tataatacaa gcaaatattc tattcattgt atttctgctt tcaaaaagtt
     2041 ctaatattga aagtataatt ccacaaatgc ctataataag tatgggaata agattagaaa
     2101 ataacacccc gagccaatct gtgaaaatta ctatatttac taatatccct attaacatac
     2161 ctatcatatt tattaaatca atttttttca ttagatattt ctcctttatt aaatctgaag
     2221 tacttatatt aaaataattc taaactattt acctcaaaaa gtgcaataaa ttatttctga
     2281 acaataaaat gatagtcaaa acaaaaaaat attgttaatc gttcagagcc atccgagagt
     2341 gtaaaatatt ttgtgtaaat gaaaaaatcc atacaaaaaa ggaaggc
//
LOCUS       DACGEU010000171         2366 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.177, whole genome shotgun sequence.
ACCESSION   DACGEU010000171 DACGEU010000000
VERSION     DACGEU010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2366)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2366)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2366
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.177"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            39..887
                     /locus_tag="IXR40_002831"
     CDS             39..887
                     /locus_tag="IXR40_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAQ4362611.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            1533..1739
                     /locus_tag="IXR40_002832"
     CDS             1533..1739
                     /locus_tag="IXR40_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HAQ4362612.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(1941..>2366)
                     /locus_tag="IXR40_002833"
     CDS             complement(1941..>2366)
                     /locus_tag="IXR40_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAQ4362613.1"
                     /translation="ADHLDPTLENKQITKFISLSGLLDPSALTQVSDKISSFLYEKCG
                     WAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNTFTKQMEEVTSVFEKAGVK
                     VTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
BASE COUNT          747 a          429 c          370 g          820 t
ORIGIN      
        1 aaaaaatgat aatcttatta tgaaaatgag gaattctcat gagcgtctcc ataagactac
       61 aaatcaaaac aatgtacaac gacttcagcc caaaagaaca ggctatcgcc gattatattt
      121 tagaaaatcc aagcaaagta agtcatagtc ctattagcaa tttagcaagt gaactgggca
      181 ttgctgactc tacttttttt caatttacaa aaaaacttgg ttataatgga tttaaagatt
      241 ttaaaatggc catgttgatc caagaaaatg atctatctgc tatttctatc cacgaaaata
      301 ttcagaaaac agatactgag ctcactatgg cgcaaaaggt gttcgagtct agtatttcaa
      361 ctttaaatga cacaaaaaag ttgttacaac aaaaggatct aaaaaaagcg gctactatta
      421 tcaatgaatc taaacgtgtc tattttttcg gtgttggcgg ttcagagatt gtagcaactg
      481 acgcttatca taaatttttg cgttccccta tcgcaacttc tcacagcacg gattaccata
      541 ttcaattgat ggaagcttct ttattgacgg aaaaagactg tgctgttttg atttctcaca
      601 cagggcaatc aaaagaaaca atccatattg ctgaaaccgt aagaaaaact ggagcaaaaa
      661 caatcgttat tactagccaa gctaattctt cccttgctaa acttggcgat gtcgttttta
      721 tttctatttc tgaagaaaca gaattccgat ctgaagcttt agcttcccgt atttctcaac
      781 taagcatttt ggactctcta tatgtgattt tgatgtttta caacgaaaaa gaatcacgtc
      841 gttctatcgc taaagttcga catactattt ctgaaatcaa agaatagcac cataacagaa
      901 aaagcgaaaa atccataaaa caaaaaaagc cactaccaaa tatttggtag tggctttttt
      961 ggttctgcaa gggtggtaca gaacatcaat agtcggtggg ttagaacgta tgtcatcgca
     1021 tctttggaga aggttgtatt ggtattattc gagttacttg ttagatgcga taacaaagtt
     1081 agtatacagt agtaaaaaat ttatcttttc ttttttttat tatttttgtt tcttattttc
     1141 taaaaaatta aaaaaaattt tggtgaatta agtatttcct tgataacact ggcttttggc
     1201 ctcattttag gttatcattt gtaattttat ttcacagttg atatgattgt tatgtaaaat
     1261 aaaaaagttt aggatacatc gaatttttgg ggaaattctt ttgggggtat cctaaatctt
     1321 ttctattata ttcccatatt ttctattatt ggtctagacg tatgatggta aactttgtac
     1381 ctatctgatt gctgaatcat taattgctta tcattagcca tctttgtttc aagttcgcta
     1441 gatgatcatt ttattcacat cctaacaaac ttgtcacatt tatagattct taatctattt
     1501 atcatacaat tataaaaaag gaggtgctgc ttatgaaagc tatccatatt tctttgcttt
     1561 ttttcgctag tgcattgatt ttatttgcta ttcatctttg ttcccagcct tatatcaata
     1621 acaacggaat attagtggaa ccagcattct tttgcttacc actcggcttt ttgtcccttc
     1681 ttgcctccgc aggcttcgga tttgttgctt tttttaaacg atcaaaacaa caaatctgac
     1741 ttataaaatt tacgtaaaag agatcgtgac aataatcgtg tgatattccc aaatttcgaa
     1801 taaaaggtgc cccttgccat ctctaactcc tcagtcacaa gttacaatat tcataaacca
     1861 tgaaaagctt gtttattgaa attgctcctt gtgacttgga gctaagtgac agattacaac
     1921 ctcttttgca tcataagact ttactccttg aaaaacatta ctaacttttg atatgtttct
     1981 tgcgcttgtt tattgctgaa atcaaactga tattcatggt tcaaaacagc atttttctcc
     2041 gcataatcta cttttgtgac tttcaccccc gctttctcaa atacagaagt tacttcttcc
     2101 atttgtttcg taaacgtatt tgtatttcca tccgttaaga atgtgttttg cgtccaacga
     2161 tccgcatgtc tgaccaaggc taaacttttg accttctctg attgttcaaa gtccttatta
     2221 tcaaagtaag cccatccaca tttttcataa agaaagctag agattttatc acttacttga
     2281 gtaagtgcag aaggatccaa cagaccagac aaagaaataa acttcgtaat ctgcttgttc
     2341 tccaaagtcg gatcaagatg atcagc
//
LOCUS       DACGEU010000172         2261 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.179, whole genome shotgun sequence.
ACCESSION   DACGEU010000172 DACGEU010000000
VERSION     DACGEU010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2261)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2261)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2261
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.179"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            <1..985
                     /locus_tag="IXR40_002834"
     CDS             <1..985
                     /locus_tag="IXR40_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HAQ4362614.1"
                     /translation="NHFKYLILSFISTFLNIAISVALMQTLYFDDKYVGRVVGGTLSF
                     VLIGLVIYLRIMIKGAHFFDKKQWRYALKISLPLIPHSLANIVLAQFDRIMINSYLGP
                     AAGGIYSYISNIGIILSVIWMSTNNAWVPWFYGEMSKNNEKKVKKVSNYYLVVFTLIT
                     MIVMVVSIDLAKFMAPKDYYSGLSLVVPITLGYFFQFLYSLPVNAEFYEKKTSFIAIG
                     TVASAIVNILLNMIFIPRLGIIAAGYTTVFTYFLLFIFHYNIAKKITNKQLFDTKKIC
                     IIIIFVSIFSLILHILINQMLIRYVLTSLLIISLVIYFLKIKNRIIDDYNS"
     gene            998..2005
                     /locus_tag="IXR40_002835"
     CDS             998..2005
                     /locus_tag="IXR40_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAQ4362615.1"
                     /translation="MFKGKTILVTGGTGSIGSEIVRQLLKYEPKAIRIYSRGEEKQFY
                     MQQELSNHTNLRFLIGDIRDSQRIDYACRDVDIIFHAAAMKHVPASEYNPMEAVKTNV
                     MGTQNVIDAAIKNNVKHFVGISTDKVVSPTNTMGATKLLSEKLIIAANQYKGKTETIF
                     SCVRFGNVMGSSGSVIPLFSKQIKNNKDITLTDVDMTRFMMSIPDAARLVLSAAMNSK
                     FGETYVLKMPAINILTLAQSLIKIYNDTHDEKYRGEIKVVGIRPGEKLYEELMTTDEI
                     ERSYENDKMYIIPPHYHATDELYKDYEKIKITAYSSDATELMSGQEFIRIAKENNVVT
                     W"
     gene            2017..>2261
                     /locus_tag="IXR40_002836"
     CDS             2017..>2261
                     /locus_tag="IXR40_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate synthase"
                     /protein_id="HAQ4362616.1"
                     /translation="MKSEVYVIAEIGVNHNGSLDLALESIDKAKECGANAVKFQTFKT
                     NKLVSKKAPMAKYQKDNLKEDSSQFEMLKKLELSQSD"
BASE COUNT          825 a          282 c          397 g          757 t
ORIGIN      
        1 taaccatttt aaatatttga ttttatcttt tatatctact tttttgaata ttgcaatctc
       61 tgtagctttg atgcagacat tatattttga tgataaatat gttggcagag tagtcggcgg
      121 aacactgtca tttgtgttga taggtttagt aatttattta agaataatga taaagggtgc
      181 tcattttttt gataaaaaac agtggagata cgctttaaaa atctctttgc cgctaatccc
      241 acattcctta gcaaatatag ttttagcaca attcgataga attatgatta attcttattt
      301 aggtcctgct gcggggggaa tatattccta cattagtaac ataggtatta ttctaagcgt
      361 aatatggatg tctactaata acgcctgggt tccatggttc tatggtgaga tgagtaaaaa
      421 taatgaaaaa aaagtgaaga aagttagtaa ctattattta gtagtcttta ctttgattac
      481 gatgattgta atggtagttt cgattgattt agcaaaattt atggctccga aagactatta
      541 ttctgggtta tctttagtgg ttccgataac cttaggctat ttctttcagt ttttatatag
      601 tttaccagtt aatgctgaat tttatgagaa aaaaacatcg tttattgcga ttggtacagt
      661 agcaagtgct atagttaata tactattaaa catgattttc atacctaggt taggaataat
      721 tgctgctgga tacacaaccg tatttacgta ttttttactt tttatttttc attataatat
      781 cgctaaaaaa attacgaata aacaattatt tgacacaaaa aaaatatgta tcataataat
      841 ttttgtatca attttttctt tgatacttca tattttaatc aatcaaatgt tgattcgtta
      901 cgttttgaca tcattattga taattagttt agttatatat tttttaaaga ttaagaatcg
      961 aattatagat gactataatt cataggagga gatataagtg tttaaaggaa aaacaatatt
     1021 agtaactggc ggaactggtt ccattggaag tgaaattgtt cgtcagcttt taaaatatga
     1081 accaaaagct atcagaattt atagtagagg tgaagaaaaa caattttata tgcaacaaga
     1141 gctctcaaat cacactaatt tgagattttt aattggtgat atcagagact ctcaaaggat
     1201 tgattatgca tgtcgtgatg tggatattat ttttcatgct gccgcaatga aacacgttcc
     1261 agcaagtgaa tataatccta tggaagctgt aaaaacaaat gtgatgggaa ctcaaaatgt
     1321 aatagatgca gcgatcaaaa ataatgtaaa acattttgta ggtatcagta cagataaagt
     1381 agtgagtcct actaacacca tgggtgcgac aaagttattg agtgaaaaat taataatagc
     1441 tgccaatcag tataaaggaa aaacagaaac aatattttct tgtgtaaggt ttggaaatgt
     1501 catggggtca agtggatctg ttattcctct ttttagtaaa caaataaaaa acaataaaga
     1561 tattactttg acagatgttg atatgacacg atttatgatg tcaataccgg atgctgcaag
     1621 attagttctg tctgctgcta tgaattcaaa atttggagaa acatatgtct taaaaatgcc
     1681 ggcaatcaat attttaactt tagctcaatc attaataaaa atatataatg atacacatga
     1741 tgaaaaatat agaggtgaaa taaaagttgt aggtatcagg ccaggagaaa aattatatga
     1801 agagctaatg actacagacg aaattgaacg ctcatatgaa aatgataaaa tgtatatcat
     1861 tccaccacac tatcatgcta ctgacgaact gtacaaagat tatgaaaaaa ttaaaatcac
     1921 tgcatactct tcagatgcaa cagaattaat gagtggacag gaatttatta gaatcgcaaa
     1981 agagaataat gtcgtgactt ggtaaggagt tttatgatga aatcagaagt atatgtaatt
     2041 gcagaaattg gtgtaaacca taatggaagt ctagatttag ctttagaaag tattgataaa
     2101 gctaaagaat gtggagctaa cgcggttaaa tttcaaacat ttaaaacgaa taagctagtt
     2161 tccaaaaagg ctccaatggc aaaatatcag aaggataatc ttaaagagga cagttctcaa
     2221 tttgaaatgc taaaaaaatt agaattatct caatctgatt t
//
LOCUS       DACGEU010000173         2253 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.180, whole genome shotgun sequence.
ACCESSION   DACGEU010000173 DACGEU010000000
VERSION     DACGEU010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2253)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2253)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2253
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.180"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            581..1540
                     /locus_tag="IXR40_002837"
     CDS             581..1540
                     /locus_tag="IXR40_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAQ4362617.1"
                     /translation="MTYTHLTPTELVMIEAYFNQSHSVSKVAHLVQRSRQTIYNVYRF
                     LKSGGSAISYYEQYKKNKRNCGRRPIVLPDGQQEYIQKKVAQGWTPDVLIGRAEFPIA
                     CSVRTLYRMFKDKTFDPHDLPMKGKRKPNGHKEKRGKQAFRRSIQDRTTDYIQFNHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPAGRQAIDIENRLNQWFQSVPKHLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNK
                     VSETFIQSVASKRNHIPRKSLHYRTPLEVFLSYVGKDDLSSLI"
     gene            complement(1527..2132)
                     /locus_tag="IXR40_002838"
     CDS             complement(1527..2132)
                     /locus_tag="IXR40_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362618.1"
                     /translation="MINSAYFHIKYLKKYEYEEVVLDYGLNRQSFLIYAINNGNLPSN
                     KKNIIIETYAYLEGGSKKLIKSCNIEYQLSVGEIKCVFEEDLELDLKKIFASIHDYIG
                     LIYKIIEDDKQTELNMCYFDREQDFFYYGGMGGGSIVPKINLVELDVNNYRELYVFNS
                     LDFEIPMKQMKNIDIHILPSESCQIEYSIEYFYKVSFVKLS"
BASE COUNT          768 a          363 c          334 g          788 t
ORIGIN      
        1 aacaataaat gaagactttt ttattgttaa ttgtttattt ttctattatt agatatgaaa
       61 atcgcattta gataaaatag aaaaatatga atatatttta aatattaaga tgagagtcat
      121 taacttatga tagtagtcaa tttgcttttc actaattaca aaatatgtga tataggaagt
      181 ttagttattg ttctcataat gccatcctgt ttttagatta tctagtaatt tttttgttat
      241 ttaaaattag gagcagtgcc aattgtttta attttaaagg ctttttttat atcttctaaa
      301 ttagaagata tttgtatatc aatatggaat atattacctt ttttgtattt ttttatgtta
      361 tctttagcta aaacatcaaa tacatgtcct tgaaattgta tcgaggcagc tggatttagt
      421 ttaaattgag gaaactttac cacagctgat tcaaaacact tgtcacattt ttttattttt
      481 ttaccttcgc cgattgtaaa attaagctag acaactaaaa aagtcatttg tgctacactc
      541 aaaatagttc cgtcgaaaga attataagga gtgagtacaa atgacctata cccatcttac
      601 accaactgaa ctcgtaatga tagaagctta tttcaatcaa tcacactctg tttcaaaagt
      661 agcccatctg gtacaacgtt ctcgacaaac catttataat gtctatcgtt ttcttaaatc
      721 tggtggaagc gcaataagct actatgaaca atataagaaa aacaaacgta actgcggaag
      781 acgtccgatt gtgttaccag atgggcaaca agaatacatt caaaaaaagg tggctcaagg
      841 gtggactcca gatgtcctta ttggtcgagc agagtttcct attgcttgtt cggtacgtac
      901 actatatcgg atgtttaaag ataaaacctt tgaccctcac gatttaccaa tgaaagggaa
      961 aagaaaacca aacggacata aagaaaaaag aggaaaacaa gcttttcgcc gttcgattca
     1021 ggatagaaca actgattata tacagttcaa tcatgagttt ggtcacctag aaggtgacac
     1081 cattgtcggt ggaaaacata aaagtgcggt gatcacgtta gttgagcgat tatctaaagt
     1141 gatcatcacc ttgaaacccg ctggtaggca agctatagat attgagaata gactgaatca
     1201 atggtttcaa tctgtaccga aacacttgtt taaatccatc acatttgatt gtggaaaaga
     1261 gttctcgaat tggaaaaaga ttagtaatac caatgatatt tcgatttatt tcgctgatcc
     1321 aggaacacct tctcaacgag gactaaatga acattcgaat ggcttattac gtaaagatgg
     1381 cttatataaa gctatggatt ttaataaggt atccgaaacc tttatccaat cggtggcatc
     1441 aaaacgaaat catattccta gaaaatcatt acactatcgc acaccattgg aagtattttt
     1501 gagttacgta ggtaaagatg atttgtctag cttaatttga caaacgaaac tttgtaaaaa
     1561 tattcgattg aatattctat ttggcacgac tcacttggca gtatatgtat gtcaatattt
     1621 ttcatctgtt tcataggtat ttcaaaatct aaactattaa aaacatataa ttccctgtaa
     1681 ttatttacat ctaactctac taaatttatc tttggaacaa tagatcctcc acccattcca
     1741 ccataataaa aaaaatcttg ttctctatca aaatagcaca tattaagctc agtttgttta
     1801 tcatcctcaa taattttata aatcaaacct atataatcat gaatgctggc aaaaattttt
     1861 tttaagtcaa gttctaaatc ttcttcgaaa acacatttaa tttctcctac tgataattga
     1921 tactctatat tacatgactt aattagtttt ttagatcccc cctccagata ggcatatgtt
     1981 tcaataatta tgttcttttt attgcttggc aaatttccgt tatttattgc ataaattaaa
     2041 aatgactgtc tatttagccc ataatctaat acaacttctt catactcata tttctttaaa
     2101 tatttaatat gaaaatatgc tgaattaatc aaaactcgag tgttactgtt gttatttatt
     2161 gttgttctat tgtgtataaa attgtatagg ttgtcatatt ttcttggttt agtgaactac
     2221 tcaccactta gctaaaccta acggtttctt acg
//
LOCUS       DACGEU010000174         2171 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.181, whole genome shotgun sequence.
ACCESSION   DACGEU010000174 DACGEU010000000
VERSION     DACGEU010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2171)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2171)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2171
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.181"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(173..481)
                     /locus_tag="IXR40_002839"
     CDS             complement(173..481)
                     /locus_tag="IXR40_002839"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362619.1"
                     /translation="MKLEIKEVVCDWGIYVDGQTYPFMIFNSKANAQEIMRIMELDNK
                     NERFDEVNKMENECEAVEYHKTCANNKYILGTMGLGKSASIKQVYEESQENCVYENSN
                     "
     gene            complement(509..862)
                     /locus_tag="IXR40_002840"
     CDS             complement(509..862)
                     /locus_tag="IXR40_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014862474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362620.1"
                     /translation="MAKKYIDNWRLFSGKLMTKESIAEMPESLEKEHILKIREMLNKE
                     GFNADLFRVGELPIEGVYYFERAVSENGVDYFSIIVEDDGSLTPQYTTLEYDENGFNT
                     FPCSTIQESIDKHEC"
     gene            complement(1170..1781)
                     /locus_tag="IXR40_002841"
     CDS             complement(1170..1781)
                     /locus_tag="IXR40_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAQ4362621.1"
                     /translation="MLVGYARVSSDDQNLERQLEEFRKIGVEKVFAEKKSGRNTVERP
                     EFNKMLSFVREGDTLVFESLERLGRNSDEILETVSFIDKNGMGLMVLNLPILDTKFGD
                     PNLEKLVRSLVINIFSWTAQNEREEIKRKQKQGIAIAKKKGVYKGKPYEYSSTAKNPQ
                     KRFIYNEIVRMLGEGVPIKRIAEKTGTNRNLVYRIKKRISESD"
     gene            complement(1821..>2171)
                     /locus_tag="IXR40_002842"
     CDS             complement(1821..>2171)
                     /locus_tag="IXR40_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAQ4362622.1"
                     /translation="KPDPKKVGRKIRSIRKKLGLTMQEFGCEVSNSPRSTVSTWEHGG
                     NLPNKAKLRKIADIANCSVEDLLFDEGFISKQSKVKLINELKEENSKLKEKIKYYECL
                     FDGIESLLNSRKNS"
BASE COUNT          645 a          438 c          240 g          848 t
ORIGIN      
        1 ctaccaatat tactattttc attcttatga attagtaaat catagacatc aaatacgata
       61 atacaaacta ttaagaacaa tataaatatt accttattgt tatatacaaa ttcagttgat
      121 tttcctatta agtataaaac taaataaatt agctcccaca tattctcact ctttaattcg
      181 aattttcata tacacaattc tcctgtgatt cttcgtagac ctgtttaata gaagctgatt
      241 tacctaatcc cattgtacct aaaatatact tattattggc gcatgtttta tgatattcca
      301 ctgcttcaca ttcattctcc attttgttta cttcatcaaa tctttcgttc ttattatcca
      361 actccatgat acgcattatc tcttgtgcat ttgctttact attaaaaatc ataaatggat
      421 atgtttgtcc gtctacataa attccccaat cgcagacaac ttcttttatc tctaatttca
      481 taaaaaacac ctttctgtag ataattaatt agcactcatg cttatcaatt gattcttgaa
      541 tggtactgca aggaaacgta ttgaatccgt tttcgtcata ttctaacgtt gtatactgtg
      601 gcgtaagaga accatcgtct tcaacaatta ttgaaaaata atcgactccg ttctccgata
      661 cagctcgctc aaaataataa actccttcaa ttggaagttc cccaactcgg aataaatctg
      721 cattaaaccc ttccttattc aacatttctc ggattttaag aatatgttcc ttttccaatg
      781 attctggcat ttctgcaata ctttcttttg tcattaattt tccggaaaat agtctccagt
      841 tatcaatata ttttttagcc attgttcttt cccctttact taatattttc tattagaatg
      901 tttatatctc ttgtttgttt tcggataata actagctccg ataactttca atttaaaaaa
      961 ataataaaaa gcccctagaa aaatactttt gagtctttat catcatattc gctcatatca
     1021 actatccttc cgatcaatga tctatattag agatttccca atataacctc ttttatttag
     1081 aagcttcttt gtataattgt acaccttaaa agtttgaaac aggcttagaa tccttctctc
     1141 gtaacattga tttctcaaag aacttaaaat caatcagatt cacttattct tttctttatt
     1201 ctatagacta aatttctatt tgttcctgtt ttttctgcaa ttcgcttaat cggaacacct
     1261 tctccaagca ttcttactat ttcattatag ataaacctct tttgtggatt ctttgcagta
     1321 gaagaatatt cgtagggttt tcctttatag actcctttct tcttcgcaat tgctattcct
     1381 tgtttttgtt ttctcttaat ttcctccctc tcattttggg ccgtccaaga aaaaatgtta
     1441 attactaagc ttctaacaag tttttctaag tttggatcac caaattttgt atctaaaatt
     1501 ggtaaattca aaaccattaa gcccatacca tttttatcta taaaagatac tgtttctagt
     1561 atttcatcag aatttcttcc taagcgttca agcgactcaa aaacaagcgt atccccttct
     1621 ctgacaaatg acaacatttt attaaactct ggccgttcta ctgtgttacg gccagatttt
     1681 ttctcagcaa atactttttc aacaccaatt tttctaaatt cttcaagctg tctttctaag
     1741 ttttgatcat ctgaactgac ccgtgcataa cccactaaca tatttaacac ctacaaataa
     1801 ttttactcta gtttaattaa ctaggaattt tttcgtgagt tcagcagact ctctatacca
     1861 tcaaataaac attcatagta ttttattttt tcttttagct ttgaattttc ttctttgagt
     1921 tcatttatca atttaacttt ggattgttta gaaataaagc cttcatcaaa aagcaaatct
     1981 tctacactac aattcgcaat gtctgcaatt tttcttagtt tggctttgtt gggtaagtta
     2041 ccaccatgtt cccatgttga cacagtgctt ctaggagaat tagaaacctc acacccaaat
     2101 tcctgcatag taaggcctaa tttttttcta atagaacgaa tttttctccc taccttttta
     2161 gggtctggtt t
//
LOCUS       DACGEU010000175         2088 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.182, whole genome shotgun sequence.
ACCESSION   DACGEU010000175 DACGEU010000000
VERSION     DACGEU010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2088)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2088)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2088
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.182"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(42..1244)
                     /locus_tag="IXR40_002843"
     CDS             complement(42..1244)
                     /locus_tag="IXR40_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit R"
                     /protein_id="HAQ4362623.1"
                     /translation="MCTKLLQNTAHKNPYKTVDEATQLDLVIVVNQLLTGYDSKWVNT
                     LYLDKSLEYQNIIQAFSRTNRLNGPEKPFGTIRYYRKAHTMEQNIEEAIELYSGKQAK
                     GLFVEKLYNNLEKLNDIFEEIKSVFNISGIENFSHLPEVPGEIKQFVNLYNQLIHCYE
                     SAMIQGFTWAKSTYEIQDYEPITVVITEYEFNILAQRYSEIEREPRDGNDSIAYDIDY
                     QLPEGSRSRINYEYLNTNFKKYMNIKEERDSNLIQSLLNDLHRTFAQLPVELQPYAEM
                     ILNDVNNGELVIKEGWEFTDYLNEYQLSEEDDFIQDLVDSTNINEALLREMLDLRLTE
                     VNINEYSRFDKLKSSVNVGHFSGYIEKNLGKMVIPIKVNMLIDRLLRAFLLEDVFDVT
                     EYIKNYFN"
     gene            1265..2038
                     /locus_tag="IXR40_002844"
                     /pseudo
     CDS             1265..2038
                     /locus_tag="IXR40_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          633 a          409 c          339 g          707 t
ORIGIN      
        1 aaagatgaat ttttttatgt actataagat gtaggtgtac tctagttaaa gtaattcttt
       61 atgtactctg taacatcgaa tacatcttct aataaaaatg cacgcaataa tctgtcaatt
      121 agcatattta ccttgattgg tattaccatt ttacctaaat ttttctcgat atatccactg
      181 aaatgaccta cgttaacact tgattttaat ttatcaaatc gactatattc attaatgttt
      241 acctcggtta agcgtaaatc caacatctca cgtaataatg cctcattaat attggttgaa
      301 tccactaaat cttggataaa atcgtcctct tcactaagct gatattcatt gaggtaatca
      361 gtaaattccc atccttcttt gataactaat tccccattat ttacatcatt tagaatcatc
      421 tcagcatatg gctgtaactc cactggtaat tgcgcaaatg tgcgatgtaa gtcgtttaac
      481 aatgattgaa ttaaattcga atcacgttct tcttttatat tcatgtattt tttgaagttt
      541 gtgtttaaat actcataatt aatacgacta cgactacctt caggtaattg gtaatcaatg
      601 tcatacgcta tactatcatt tccgtctcta ggttctctct ctatctcgct gtaacgttgt
      661 gccaagatat taaattcata ttctgtgatt actactgtta taggttcata atcctggatt
      721 tcataagtcg attttgccca tgtgaatccc tgtatcatcg ctgattcata acaatggatt
      781 agttgattat aaagatttac aaattgctta atttcccctg gaacctccgg taaatgactg
      841 aagttttcta tgccagaaat attaaatacg gacttaattt cttcgaatat atcgttcaac
      901 ttttctaagt tattatataa tttttcaaca aataaccctt ttgcttgttt gcctgagtat
      961 aactcaatag cctcttcaat gttctgttcc atcgtatgtg ctttacgata ataacgaatg
     1021 gttccgaacg gtttttcagg accattaaga cgatttgtgc gtgaaaaagc ctgaattatg
     1081 ttctgatatt caagtgactt atctaagtat agggtgttga cccattttga atcgtaaccc
     1141 gttaagagct gattaacaac tataacaaga tctaattggg ttgcttcatc tactgttttg
     1201 taaggattct tatgcgctgt gttttgcaat agttttgtac acaagattgc aaagaaaagt
     1261 acacaatgtt gccacttctg gttccatgag ttttatttgt gttgatggga caaccaatca
     1321 gctatttacg acccttgaag atcgcagact ttacaaacta actcaatact tcctgcgctt
     1381 tcctagaaag gcccgtttaa aggtcaagta cctagtgatg gacatgaatg ccagctattg
     1441 tcagttgctt aaaacggtct ttccaaatgc ggagatcgta actgaccgct ttcatattgt
     1501 ccaacacatc aatcgcagct tcaatcaatt acgtgtccag atcatgaatc gttttcgaac
     1561 ctcacactct gaaaatcaga agaagtaccg tcggctcaag cgatattgga aactcttact
     1621 caaagattcc acgacatggg aggcactcaa acggcattat catcgactgt ttaaacgacc
     1681 aattagtcaa acagaaatcg ttaatgagct gttaagctac aacgaagaat tgcgaactgc
     1741 gtatcatttt tgtcaattat tacgctatta tttcgttaaa cgagatacgg taggctttca
     1801 agaaaccctt aaaacaattt catctacgtt acctcagtcg tttaaaaaga aattcacgat
     1861 cttccatcgc taccaatcgg gtatttcaaa tgcctttaag gtgtcccact caaacggcgt
     1921 cactgagggg ctgtataaca agatcaagct gattaaacga attgcgtttg gttatcgcaa
     1981 cttttataac tttcgggcac ggatctattt acaacaaggt ctgatctttg aaaactaaaa
     2041 aaatatgcgg cgcacagaac gcgccgcata tcggactaag ttttattg
//
LOCUS       DACGEU010000176         2056 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.183, whole genome shotgun sequence.
ACCESSION   DACGEU010000176 DACGEU010000000
VERSION     DACGEU010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2056)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2056)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2056
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.183"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            493..714
                     /locus_tag="IXR40_002845"
     CDS             493..714
                     /locus_tag="IXR40_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362624.1"
                     /translation="MRVIKSEKFTLAEIMTTSELAQELDYNQAYVLRLAKEHLTEGKE
                     YRSAGRRNYLFSPEALKKLEKVITTKEGE"
     gene            715..972
                     /locus_tag="IXR40_002846"
     CDS             715..972
                     /locus_tag="IXR40_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362625.1"
                     /translation="MPKETTINVEQLEKLLESYSNDFIELTGGKVEETTDLFDLLLTN
                     ILELNSEEQKEHKGKLIAPSYRKVAKSAVPTGFLTKQPYIF"
     gene            complement(1108..1710)
                     /locus_tag="IXR40_002847"
     CDS             complement(1108..1710)
                     /locus_tag="IXR40_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HAQ4362626.1"
                     /translation="MTSRKTKDERTRNWTFVVYPESAPENWREFLDELHVPWVESPLH
                     DKDVNPDGELKKPHWHVLIMFSGKKTYDQIREITQKLRSPNPQKCANAKGMVRYFAHM
                     DNPEKFQYAKSDIIAHGGAEIASYLSVTSAERYELIREMMSFVDSKNITEIKDLIDYA
                     MSERFDDWFPLLCDNSAYIIGQYIKSNRHGGSVNSKINKG"
     gene            complement(1777..1932)
                     /locus_tag="IXR40_002848"
     CDS             complement(1777..1932)
                     /locus_tag="IXR40_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010001600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAQ4362627.1"
                     /translation="MISNEKKRVVVTLTKEVADNLDKIAKQMGLSKSGLITIWVNANG
                     KENEQKK"
BASE COUNT          678 a          462 c          314 g          602 t
ORIGIN      
        1 aaaaaaaaac gctgaaaccc ttgggagagt aaggctaaac agctatcgac caatgaccaa
       61 tgaccaataa ggggggtgtc gtagtccccc cctcctccgc ccaattcata aacaccaaaa
      121 ccaaaaaaca aacctcaggg ctccgccccg aaccccgacc tccttctacc gaaatatatg
      181 caggcgccac gcttactatt tcgttcagct atcggctttt gcaatctaac acgaccgttt
      241 cgctaccagt cgccttacag gctccattct cgcttctctt acgtgtttta acgattgcgc
      301 cgataactaa acgaaataga cgctaaatcg cttaaaacgc aaaatagacc ctttttagag
      361 cattgatttt ttctactagt catttcgata atataaaatt gaccacaaca cagaaaactt
      421 atattataag cttatgtcgt aagtccgacg tactcacgta atatagacgg acgttaaatg
      481 gaaggagcat aaatgagagt gataaaatca gaaaaattca ctttggccga aattatgacg
      541 accagcgaac ttgcacaaga acttgattac aaccaagctt acgttttgcg cttagcgaaa
      601 gaacatctga ctgaaggaaa agaatatcgc tctgccggta gaagaaacta tcttttcagc
      661 ccagaagccc ttaaaaaact agaaaaagtc ataaccacca aagaaggtga gtaaatgcct
      721 aaagaaacaa ctatcaacgt tgaacaacta gaaaaattgc tagaatcata ttccaatgat
      781 tttatcgaat tgaccggcgg aaaagtcgaa gaaaccaccg acctctttga cctacttctc
      841 acaaatattc tggaattaaa ctctgaagaa caaaaagagc ataagggaaa actgatagca
      901 ccttcctaca ggaaggtggc taagtcggct gtgccaactg gttttcttac aaaacaacct
      961 tatatttttt gatatcacaa aaaaatccat tttggaccta ttttcggtca taatatagta
     1021 cctacttttg gtcatagttt cgtccgtagt tttggtcata gtgactaaga ctttcacgca
     1081 caaaaaaaga gctgaaatta acagctctta tcctttattt atttttgaat ttacacttcc
     1141 accatgacga ttcgatttta tatattgccc gataatataa gctgaattat cacaaagaag
     1201 cggaaaccaa tcatcaaatc tttctgacat tgcatagtca attaaatctt tgatttcagt
     1261 gatattctta gaatcaacaa acgacatcat ctctctaatc aactcatatc gttctgcact
     1321 cgttactgac aaataactag caatttctgc accaccatga gcgataatat cacttttagc
     1381 atattgaaat ttttctggat tatccatatg agcaaaatat cgcaccatac cttttgcatt
     1441 agcacatttt tgcgggtttg gagaccgaag cttttgagtt atctcacgta tttgatcata
     1501 cgtcttttta ccgctaaaca ttatcaaaac atgccaatga ggctttttca attcaccgtc
     1561 aggattcaca tctttatcat gaagtggact ctcaacccaa ggaacatgta actcatctaa
     1621 aaactccctc caattttcag gagccgattc aggatagact acaaacgtcc aattccttgt
     1681 gcgttcatct ttagtttttc tactcgtcat gctataatta ccttaattga acaacagtct
     1741 aacagcaaaa gcagtgcgcc aacactaatg cttttgctat tttttttgct cattttcctt
     1801 tccgttagca ttaacccaaa ttgtaataag accagactta ctaagaccca tttgtttcgc
     1861 aattttatca agattatctg ccacttcctt agtaagcgtt acaacgactc tctttttttc
     1921 attactgatc ataattcgta tcctccaacg actttttctt aaaaaccata gtaacaaaaa
     1981 agtaactaag gtgcaacagt ttagatacta attagcgaat aataggcctt aaacccttgg
     2041 cattactgat tttgtc
//
LOCUS       DACGEU010000177         2049 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.184, whole genome shotgun sequence.
ACCESSION   DACGEU010000177 DACGEU010000000
VERSION     DACGEU010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2049)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2049)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2049
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.184"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(129..416)
                     /locus_tag="IXR40_002849"
     CDS             complement(129..416)
                     /locus_tag="IXR40_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362628.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
     gene            complement(587..1939)
                     /locus_tag="IXR40_002850"
     CDS             complement(587..1939)
                     /locus_tag="IXR40_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH dehydrogenase"
                     /protein_id="HAQ4362629.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ
                     "
BASE COUNT          560 a          407 c          355 g          727 t
ORIGIN      
        1 aaaaaggggt tgacaaagct tgtcataacc cctttttctg attaaaagat agtaaagaga
       61 cagtcatcgg taattgtgat gattttttgt catcacttaa ggatgagcgg ccttttcaaa
      121 aactgtcttt aaagatcatc atcagtttct agcacatatg gctgaccttc atatgtgtac
      181 tctgtattca atgtgccgtc attttcatct gagtagatgc gtctactgaa aggaaaacga
      241 tgagaaacat tatctttggc atcatttgct ggcatcgtgt aatattcctc ttgcgtttca
      301 ttcaactgag agagtacttg atctgccaac tcatcaatat tgatcgttaa tttcttcgaa
      361 gcacttttat aatcttctaa aaatgcatct tgttggacaa aatattcttt attcatcttc
      421 tttctcacct ttcttttcaa aatcaaataa agctgcttgt tcttttatgt aacagcttta
      481 tctttgctgc ttattgtgac aaaaaattcg aagaaagaca actaattgta cttttcacaa
      541 aaaaagacag agggtcgtga caaaattgtg tcacaaccct ttttctttat tgtgcagttt
      601 cgatttcgcc tagcgctgct tgtgcaagta ggttcaagta attccatggg cggtcaaaat
      661 gtggttggaa gaagaaatct gaaagtgcga gatcttctac agtcatttta ttttgaacag
      721 ctaaagacat ggtatttgct gattgtgtaa tgtcgtattt ggacatgaac tgagcaccta
      781 cgatacgatt cgttcctttt tcatagacta gctccatcat tactttttca gtagttggca
      841 tgaactctgg acgataatta tcttcaaata cagtcgcttg gacttctaga tcgttcaaag
      901 ttgcgctttc tttggtcaca cctgtcgaac cgatcgtcca gccaaatagg taaagtcctg
      961 aagttccttg agtaccacga tacgccattt tatgatctgt caagttattt cccacaagca
     1021 aaccttgacg aacggcattt gttgccaaag gaatatagtt ttgcgtgcca cttggattgt
     1081 agttgactac tgcagagtct ccagctgcaa aaatgtctgg attacttgtc tgcatgtatt
     1141 cattcacttt gattgccccg tttggcagtg tatctacttt tccttcgatc agttttgtat
     1201 ttggacggaa gcccacacat aaaatgacca tatctgtatc aaatgtatct gttggtgtag
     1261 ctacttgttt cacttttcct tcttcatctg tgataaattc agtaacattt tcgcctagcg
     1321 caagagtaac accgcggtct gtcaattctt tttctaagat atctgtgaat ggtttatcta
     1381 gatatttatt caagatgcga tctaatccat caatcaatgt cacttgtttt ccagattcga
     1441 caaaagcttc tactaattca ataccgatat atccaccacc aacaattact acacgttttg
     1501 cttctttcgc ttgtgcaata atttcatttg cttgattgta gtttttgcat aggagtacat
     1561 ttttcgcatc gattccacta atcggtggga taataggcca tgaaccagtt gtcatcacta
     1621 atttatcata agaaaccgtt tctgtttctc ctgttttcag atcttttgcc gttactgttt
     1681 tattttctgt atcgacgtct gttacatcgt gttccatttt aactgttgct cctaatgaag
     1741 ataattcttc aggatttgag tagaacaagc ctgctgggtc ctttactact ccgccgacat
     1801 aaagtgcgat accgcaagat aagaaagaaa tattgtcatt tctttcatat actgtcactt
     1861 ctgcttctgg atgatttttt aaaatacttt ttacagctgc agtacctgca tgagtacagc
     1921 caattactac tactttcatt tatggtccct ccgattaaca ttttgtcctt cgacaaaact
     1981 actataacag aaataaaacg gatacaacag tttaatgctt gtgaattcac aaaggtttgt
     2041 ttgtagttt
//
LOCUS       DACGEU010000178         2004 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.185, whole genome shotgun sequence.
ACCESSION   DACGEU010000178 DACGEU010000000
VERSION     DACGEU010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2004)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2004)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2004
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.185"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            <1..378
                     /locus_tag="IXR40_002851"
     CDS             <1..378
                     /locus_tag="IXR40_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HAQ4362630.1"
                     /translation="KNVSTEDFFNYCRLEESGVTVTSGTDLPLFITDIPESIIRAVFR
                     RFPEGEEVWEKETSFTTTELLKSFTSNSFKVNGLSEYGEIKVGKSASLAVFSEDLCTD
                     DWQKVMAAEVIATYLDGDLVYKK"
     gene            426..1826
                     /gene="yfcC"
                     /locus_tag="IXR40_002852"
     CDS             426..1826
                     /gene="yfcC"
                     /locus_tag="IXR40_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HAQ4362631.1"
                     /translation="METMKRKFTFPHSYTLIFILIILAAILTWIIPSGQFETVVENVA
                     GMEKTTVVPGTYHQIDKADYGQGFSSILMAPAEGIISAVEVVAFVLIVGGAFGIILKT
                     GAIDRGLFTLAKVLGDKGILVIPMSMILFSLGGSTFGMSEEVIPLFAVFISLMFSLGY
                     DSMTAILILFLSTQAGYVGSTINPFNVLIAQGVAGVYGNPLLWFRMLSWIVITGISIV
                     FTMLYASRVKKNPLSSIVYESDLKVKHKFQNFDTEKEFSTQDKLIIAGFIVGLGIMIW
                     GIISKGWYMVEISALFLGLGLFAGGIARFSQKEIAEAFVEGCSDFAYAAVIIGLARGV
                     LVILEGGMIIDTILNSLANLLGGLPKFLFTTILLISQVIVSFFVPSSSGAAALTMPVM
                     APLGDLMNVSRDVVVLSNQFGNGLMNIISPTSGVLLAGLAIAEINFSKWFKVGFKIFA
                     ILTLVSAVLLYIATLF"
     gene            1859..>2004
                     /locus_tag="IXR40_002853"
     CDS             1859..>2004
                     /locus_tag="IXR40_002853"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HAQ4362632.1"
                     /translation="MIKINQLAGMNIHYLFYSLKEFFAYQQKIGISSVELWGGAPHFF
                     IDAFT"
BASE COUNT          555 a          340 c          432 g          677 t
ORIGIN      
        1 aaaaatgttt ccacagagga cttctttaat tattgtcgat tagaggaaag tggtgtaaca
       61 gtcactagcg gtacagattt accgctgttt attactgata ttcctgaatc gattataaga
      121 gcagtattcc gtcgttttcc tgaaggagaa gaagtctggg agaaagaaac aagcttcacg
      181 acaaccgagc tgctgaaaag ttttacaagc aacagcttca aagtaaatgg tttatcggag
      241 tacggagaaa taaaagtagg gaaaagcgcc agcttagctg ttttcagcga ggacctctgt
      301 actgatgact ggcaaaaagt gatggctgcg gaagttatcg ctacctatct tgatggtgac
      361 ttagtttaca agaaataatg cttttcgata taacgttata aaacgaatta aagagaggtt
      421 aaaaaatgga aacaatgaaa agaaaattca ccttcccaca tagttataca ttgattttta
      481 tcttaattat tttggctgca attttaactt ggataattcc tagtggtcag tttgagacag
      541 ttgttgaaaa cgtcgcaggt atggaaaaaa caacggttgt tccgggaacc tatcaccaaa
      601 tcgataaggc agattatgga caaggttttt cctctatact aatggcacca gctgaaggga
      661 ttatttcagc tgttgaggtt gttgcttttg ttctcatcgt tggtggtgcc ttcgggatta
      721 tcctaaaaac gggagccatc gatcgagggc tgtttacctt agcaaaagtt ctgggagaca
      781 aggggatctt agttattccg atgtcgatga ttctattcag cttaggagga tcaacctttg
      841 gcatgagcga ggaagtcatt cccttatttg cggtgtttat ttctctgatg ttttctcttg
      901 gctatgattc catgactgcg atcttgattc tatttttaag tacacaagcg ggatatgttg
      961 ggtcgacgat taatcccttc aacgttttaa tcgcacaggg agtagctggc gtttacggaa
     1021 atcccctgct ttggtttcgg atgctatcct ggattgtcat tactgggatt tcaattgttt
     1081 tcaccatgct ttatgctagc agagtcaaaa agaatccact gtcctctatt gtttatgaga
     1141 gtgatttaaa ggttaagcat aagtttcaaa attttgacac tgaaaaagag ttttcaacac
     1201 aagataaact aattatcgcc ggttttatcg taggtttagg aatcatgatt tggggtatca
     1261 tttccaaggg atggtatatg gttgaaattt ctgcactatt cttaggatta ggtctttttg
     1321 ctgggggcat cgctagattt tctcaaaagg aaattgctga agcttttgtc gaaggctgtt
     1381 cagatttcgc ctatgctgct gtaatcattg ggctagctag aggagtcttg gtaatcttgg
     1441 aaggtggaat gattattgac actattctaa acagcttggc taacctttta ggtggtcttc
     1501 caaaattcct gttcactacg attctactca tttctcaagt aattgtttcc ttttttgttc
     1561 catcctcctc aggagctgcg gcattaacga tgccggttat ggcaccattg ggtgatctaa
     1621 tgaatgtaag tcgtgatgtt gttgttctaa gtaaccagtt tggaaatggt ttaatgaata
     1681 ttatctcccc aactagtggt gtattactgg caggattagc catcgcagag attaatttct
     1741 ctaaatggtt taaggttggc ttcaaaatat ttgccatctt aacccttgtt tctgctgttt
     1801 tgttatacat tgctacactc ttttagtctt aatcatccat taataggagg caatagttat
     1861 gattaaaata aatcaattag caggaatgaa tatccactat ttattttatt ctctcaaaga
     1921 atttttcgct tatcaacaga aaattggtat ttcttctgtt gaactttggg gaggtgctcc
     1981 gcattttttc atagatgctt ttac
//
LOCUS       DACGEU010000179         1982 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.186, whole genome shotgun sequence.
ACCESSION   DACGEU010000179 DACGEU010000000
VERSION     DACGEU010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1982)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1982)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1982
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.186"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            7..816
                     /locus_tag="IXR40_002854"
     CDS             7..816
                     /locus_tag="IXR40_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAQ4362633.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            856..1353
                     /locus_tag="IXR40_002855"
     CDS             856..1353
                     /locus_tag="IXR40_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAQ4362634.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(1738..1811)
                     /locus_tag="IXR40_002856"
     tRNA            complement(1738..1811)
                     /locus_tag="IXR40_002856"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1775..1777),aa:Ile,seq:cat)
BASE COUNT          681 a          352 c          358 g          591 t
ORIGIN      
        1 gataaaatga aactagcagc gattgattta gacggtacct tgcttgatcg aaatggaaag
       61 ataccagaag aaaatatcca agcacttcgg aaatttgatg aaaatggcgg aatcgtaacc
      121 gtcgctaccg gaaggaacag catttctgct aaagatattt tttccgaatt aggaatcggt
      181 ggctatttga tttcttccaa tggttcactg attgctgaaa tgaaggatgg aaaaatggcg
      241 aaagttctca gacgttcaaa aatagatagc gatacactga gaaaagcctt cttctatgct
      301 caagaagcga aaatatccat cattgctagc cgagaaaccc aagatgatca gctgacattc
      361 gatgaatcaa atctagtcaa agatgaccct tattatgaac atttcaattt acagaaccat
      421 tcttttgatc aaattttaaa tatgttggaa gatccttctc ttagctatct taaattagca
      481 ttaacagata agagtgaaga aaaactacag aagctacaaa gagatctgca agcagatggt
      541 atccaatcag tattctctga tccgcatttc ttagaaatca cgcctacagg tatcactaaa
      601 gctcattcac ttgtttttct ggcggattac cttggaatcg aatcgagtga catcatggct
      661 tttggcgatc aagaaaacga cattgctatg ttgaattaca gcgggttgag tattgcgatg
      721 gggaatgcac agcgacaagt aaaagaaatt gcaaaccaag taacactgac gaatgaagaa
      781 gctggtgttg cttatatttt aaaaaacttc tattaaaaag aataaaatga cgatatgaat
      841 gtaggaggaa agaaaatgtt agttattatt gatatgcaaa atcatattct tgatccaaac
      901 agcgaatttt atattccaga gtcagatcaa ttggcagaac gtattgctca aagattagct
      961 aaagcacgcc aaaataatga atatattctc ttcacacggg atataccagt tgaactgaag
     1021 gacaaagaag aagaacgaga agatttgcaa ttgatccctc ttctttctcc acaagaaaat
     1081 gaacgagtga ttaaaaagta ttactttacg attccacctg aaactttagc tgaaatccag
     1141 gaaactttat ttgaaagcaa agaagaacaa aaagagatcg aagtagtcgg gattgaaaca
     1201 aacttgtgtg tactctctaa tctgataggc ctgcagagtg cttttcctga agcagacttt
     1261 tttgttgatc caatgttagt ctccagtaga aaacacggag aatccgcttt agagctgttg
     1321 aaagatttca acgtctctat cgtcgaatca taaaaatatc tatcttcatt tacgatattt
     1381 aacacacaat aaaaaaagca cgcagaactg ttttagtcct acgtgctttt tctatcaaag
     1441 tagattggct tttttatgac acagagtgaa acggcaggct cacgacctct ttcttaaatg
     1501 gtgttcaatc agctgaccct cggtattagc ttaacaaacg gcaaaatatg aggaactatt
     1561 tttccgtttg ttaagctaat actcaggtca aaacgctgat ttcacaacct cttccttaaa
     1621 cggtattcaa aagcttgcat ctgcagtaat aagaacagcc aagtaaaaac ataagaagct
     1681 gtttttactt ggctgttctt attacttgat gcagggcagc tttttcacaa cctcttatgt
     1741 accttgtagg actcgaacct acgaccggac ggttatgagc cgtctgctct aaccaactga
     1801 gctaaaggta catcataaat aaaatttatt tttgttactt ttcaactata gcacgaatga
     1861 caaactctca caagtttcaa aatataagta aaataatatt gttattctta tttcttttac
     1921 ttgtgtcata actattttgt tactttaatt tttatttgct tattttagaa aaaatgttat
     1981 tc
//
LOCUS       DACGEU010000180         1916 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.187, whole genome shotgun sequence.
ACCESSION   DACGEU010000180 DACGEU010000000
VERSION     DACGEU010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1916)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1916)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1916
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.187"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            749..1081
                     /locus_tag="IXR40_002857"
     CDS             749..1081
                     /locus_tag="IXR40_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HAQ4362635.1"
                     /translation="MSYTGILSLEDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYAGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIS"
     gene            1700..>1916
                     /locus_tag="IXR40_002858"
     CDS             1700..>1916
                     /locus_tag="IXR40_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HAQ4362636.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYYQKLTDNPIGFGLLPEDDEGNE"
BASE COUNT          665 a          268 c          384 g          599 t
ORIGIN      
        1 tattttaata gaatttatga gttaaaatat tatgataaaa atcacaaacg tagcttttta
       61 cgtcataagt gttaatagtt aataattaat ttccaacaca aaaaagagaa caaacgtttg
      121 catgttgctg ttttttagtt ataataatac gcgaagagag gtaatttcat tttttaaaaa
      181 agctaaaaac cttgatatta cttcttttca ggcaatacga atattattcg cttacatttt
      241 tttgtataaa tttagttgtt ttaaatttaa ttgtctgcta cgcttgtgat gaattaattt
      301 tcgttctgca cttttggacg ataaatttgg acaattgaaa atacaaaaaa aagaaaggcc
      361 ctgtgagact cggaaggctg gtaaccttcg tcgacgtcca caggtggcat taagacaacc
      421 tttaatccct taatgcgttt acctttcagt gttacggtat tacccgcaac ggatttagta
      481 taacagatat tcaaaagtga taccactttt tttggctgtg ttaaggttaa aaatacgtga
      541 tattacgatg aatctatgcc taagcataat gttataaaaa tgtccgtgtg gctctttgcc
      601 gtatgacgaa cgctgaaatt agagggaacg catgtttgga tgcgttccct cttttttgtt
      661 tgtcatgaac gaaaatcaat tctctatttt tgaaaaataa caagaaaaac ttattaaaaa
      721 tatttaaagt aagtgggtgg attattttat gtcatataca ggaattttga gtctcgaaga
      781 tatttgtcac tacggtaaac ggtgtaccgc tacagagaaa atcacgaaga aactatcaac
      841 tggccaaagt aaaaccgttg tgcagtgtaa gaaatatata atccagaaag acaaagtctc
      901 agaggaaatg atttattacg ctggtaaaca aaagcaaata attttaaaag atcctatccc
      961 tttaaaagaa ctatatccaa caatcaaaca tgtttatgac caaaacggtg tactgattgg
     1021 tcgaagaaaa aatggagtct tgcgttgtac cgcaaaaggg atggggcgtt taatcagctg
     1081 aattgatcat tctcataact tgtattttat cgtttttcgc ttgcttgaaa atattgtcga
     1141 gacttctaaa agaacttaga attactagaa aaataaggag tagacttgat ctatcaacaa
     1201 ttcctttcgg ggggtgacgg ggtaggtttt tacgattggt aacgtaaaaa attggtcaat
     1261 cgagtaaatg cccttgtttg gatagtggtg aaatgaattt gtgtaaataa tatgcacaga
     1321 gtaaacaaga gggaatttag aagttagaca agttagaata gcgcctagat taatcatgag
     1381 cagctactaa gggatctagg ctttgacgca aactcatgga ataaggagta ggtcttctcg
     1441 taatggggag gacgcacaag aaattgtgtc gtgtgctgca gtacatgtag atacttgcga
     1501 ggacgttggt cattggatca atcgagcatt taccgatttc tactagggtt tctcgtttcg
     1561 gacgccataa acgagtcgat attttttatg tatttttaag taaacgaaaa acgataaaat
     1621 atgaacgagt cctgaataaa gtgaaaaaat tgatataaaa catagagaaa atgaaattta
     1681 cgtaatggag gaatgacaaa tgaaaaatta tgatccgaat atacgattgg gcacacatac
     1741 tattaaggtt tctttccaac gttgggatta caaaggattt gtgacgttta gaagaggcgg
     1801 aaattgtaaa ggattagatg ttttagcatt agacgaggat gatttatact atcaaaaatt
     1861 gactgataat ccaattggat tcggcttgct acctgaagat gatgaaggta atgaat
//
LOCUS       DACGEU010000181         1898 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.188, whole genome shotgun sequence.
ACCESSION   DACGEU010000181 DACGEU010000000
VERSION     DACGEU010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1898)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1898)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1898
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.188"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            123..1292
                     /locus_tag="IXR40_002859"
     CDS             123..1292
                     /locus_tag="IXR40_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAQ4362637.1"
                     /translation="MTKFTIEIMQTLLNKGDLDELFQDHLERAINSLLQAELTAFLDY
                     EKYDRNGFNSGNSRNGNYSRTFKTEYGELNLTIPRDRNGEFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMAEISKLIEKMYGHHYTPQTISNMSKLVAEDVLAFKERTLEANYSVI
                     FMDATHIPVKRQTVSKEAVYITIGIRLDGTKEVLGFTIAPTESAYIWKEVLQDLRKRG
                     LEEVLLVVTDGLSCIEESIHSVYPNAQFQQCCVHVSRNIAHKVRVRGRKEICEDFKLV
                     YQANSKEEALDHIDFMTRKWKKQYPRVVNLLLNPALLTFYNFPHAIRRTIYSTNLIEG
                     FNKQLKRYTRRKEQFPNEESLERFFISQFNQYNQKFLGRIHKGFKEIQDTLESMI"
     gene            complement(1617..>1898)
                     /locus_tag="IXR40_002860"
     CDS             complement(1617..>1898)
                     /locus_tag="IXR40_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAQ4362638.1"
                     /translation="ILSNLISNAVKYTDVNGVINIGIVNDWLYIENSYGNNKISNMDK
                     IFDVKFDLNKENSNGLGLYIVSNILNNYNIEYKVLQDEEFFIFKIKIFS"
BASE COUNT          682 a          306 c          273 g          637 t
ORIGIN      
        1 ttttacactc tctattatga tagcgtaaaa tattttgtgt aaatagaaat ttagggtaga
       61 aaaaaaagtc cattctgtaa aattaaagtt accacacaga aattttatag gaggactttc
      121 tcatgactaa atttactata gaaattatgc aaacactact caataaaggg gatttagatg
      181 aattatttca ggatcattta gagcgagcga ttaattcact tctacaagca gagctaactg
      241 cttttttaga ttacgaaaaa tatgatcgaa atggattcaa ttcaggaaat tcccgtaacg
      301 ggaattattc acgtacattt aaaacagaat atggcgagtt gaatttaact attcctagag
      361 atcggaatgg cgaattttct caacaaacac taccagcata taagcgaacc aatgattcat
      421 tagaaacgac cattatccaa ttatttcaaa aaggcattac tatggctgaa atctccaaat
      481 taattgaaaa aatgtatggt caccactata cgccacaaac aatctccaac atgagtaaat
      541 tggtggctga agatgtttta gcttttaaag aaagaacgtt agaagccaat tattccgtta
      601 tatttatgga tgcgacgcat atccctgtga agcgacagac tgtttcgaag gaagcagtgt
      661 atattacgat tggtattcgt ttggatggaa ccaaagaagt tcttgggttt actattgccc
      721 caactgagtc tgcttatatt tggaaagaag ttcttcaaga tcttagaaaa cgtgggttag
      781 aagaagtttt attagtagtg acagacggat taagctgtat tgaagaaagt atccatagtg
      841 tgtatccgaa tgcccaattt caacaatgtt gtgtgcatgt atctagaaat atcgctcata
      901 aagttcgtgt tcgaggtcga aaagaaattt gtgaggattt caaattggtt taccaagcga
      961 attcaaaaga agaggcattg gatcacatcg actttatgac taggaaatgg aaaaagcagt
     1021 atccaagagt cgtcaattta ctcttgaatc ctgccctatt aaccttttat aatttccctc
     1081 acgccatcag acgaacaatt tattcgacga acctgattga aggctttaat aagcagctaa
     1141 aacgatatac tcgaagaaaa gaacaattcc ctaatgaaga atctctagag agattcttca
     1201 tttctcaatt taatcaatat aaccaaaaat ttttaggtag aattcacaag ggatttaaag
     1261 aaattcagga tacattagag tcgatgattt aactgtaatt aacagaatgg attttccatt
     1321 tacatataat tcttgacgct accataatct aaataaccat catattcatc tactacttat
     1381 ataattgagt tttattaaac tttttaagtt tctattctat caaatattta aacaatctct
     1441 gcatccgaaa agactacctc gtatagtttt actaacaata tttttattag cgtgttcaaa
     1501 tcctgatttc ttgtatcaat tattttctgt tcactttcaa taagaaaaaa gtctttactt
     1561 ccatggataa taataagtct ctatttttca ataactattg caaaattata tcttaattaa
     1621 gaaaatattt ttattttaaa gataaaaaat tcttcatcct gcaatacttt atattctata
     1681 ttgtaattat tcagaatatt acttacaata tataaaccta atccattact attttcctta
     1741 tttaaatcaa atttaacatc aaatatttta tccatattcg aaattttatt gttaccgtat
     1801 gaattctcta tatataacca atcattaact atcccaatat taattacccc atttacatca
     1861 gtatatttta ccgcattact aatcaaatta gatagaat
//
LOCUS       DACGEU010000182         1854 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.189, whole genome shotgun sequence.
ACCESSION   DACGEU010000182 DACGEU010000000
VERSION     DACGEU010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1854)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1854)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1854
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.189"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(140..1288)
                     /gene="tnpB"
                     /locus_tag="IXR40_002861"
     CDS             complement(140..1288)
                     /gene="tnpB"
                     /locus_tag="IXR40_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family element transposase accessory
                     protein TnpB"
                     /protein_id="HAQ4362639.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYTTNNQNGTVALIDSKFIKVPKLKSLVRIKLHRQPKGIIKSATISRHSS
                     GKYYISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDNNKFTSKMEKKLKREQ
                     RKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTDFLNKLSTEMIKNHDI
                     ICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRKIIKVDKWFPSSQICS
                     ECGHKDGKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLHSMGLA"
     gene            complement(1305..1709)
                     /locus_tag="IXR40_002862"
     CDS             complement(1305..1709)
                     /locus_tag="IXR40_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="HAQ4362640.1"
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERIS
                     ESYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLWKE
                     MFWSKSFCLLTTGGAPIDVIKKYIQNQGNNHK"
BASE COUNT          551 a          329 c          299 g          675 t
ORIGIN      
        1 taaacctgac ggttcttaac gcttgaagtg ggagcttctt gggaatagag catacttgat
       61 agcgtatttc tttactaaca gcggtgtctc ttatttacca agctatcccc gtagttccta
      121 cggttcttga tgattggatc taagccaatc ccatagaatg tagtcttaga ccttcggtca
      181 gaatattgat actagcattg atatcacgat catgatgagt atgacaaaca ggacaagtcc
      241 attctcgaat ttcaagagat ttcttgccat ctttatgtcc gcactctgaa caaatctgac
      301 tagacggaaa ccatttatct actttgatga tttttcgtcc ataccagtca gccttgtatt
      361 gtaatttagt cacaaacttt gaccaagaaa catcagaaat acttttagct aatttatgat
      421 ttcgcaacat accttttgtg tttaagtctt caatacagat aatatcgtga tttttgatca
      481 tttctgtact caacttattc agaaaatcag tacgttgatt cattactttt tcatgcaatc
      541 tagctacttt gcgtttttgt ttttgataat ttttagcttc aaatagattg gtacctttat
      601 ttttagccaa taaagcacgc ctagacaatt tgcgttgttc acgctttagt ttcttttcca
      661 ttttggacgt gaatttatta ttatcaattt tttgtccatc agaaagaatc gcaaagtcca
      721 taatacctaa gtcaatacca attgtggaat tagttttagg taattcgata atttcttctt
      781 tacacaacaa agaaatatag tatttaccgc tagaatgacg tgatattgta gcagatttga
      841 taatcccttt tggttgtcta tgaagcttaa ttcttactaa tgacttcaat ttaggaactt
      901 tgatgaattt actatcaatc aaagcaactg taccattttg attattcgtt gtataactct
      961 gaacaggatt tttcttactt ttgaaacgtg gaaatccaac ggatttatcc cgaaaaaaat
     1021 tcttgtatgc tttatctaaa ttaagttggg cattggctaa agcaaggcta tcaatttctt
     1081 tcaaaaacgg aaattctttc ttgtatttag ctggtgtcgg aaaagtcatt tttttagaag
     1141 aatcattttt aacttcttca tacgcctttt ttcggtcatc aagcattaga ttgtagacct
     1201 tacggacaca accaaaagat ttggcaaaga agatttcttg ttcctctgtt ggatagattc
     1261 tgaatttgta tgcttttagt tgttccataa agttcaccta ctttctattt atgattgttt
     1321 ccttgatttt ggatatactt cttaatcaca tcaattggtg cgccaccagt tgtcagaaga
     1381 caaaaacttt tagaccagaa catttctttc caaagaaatt gtttgactct tggaaagtca
     1441 cgttttatca atcttgagct ggcactttta taggcattga tgaattttgt caattctgtt
     1501 ttaggttgag ctttgaacat aatatgaacg tggtctttat catgattcca ctccactaaa
     1561 gtaatgtgat acgattctga aattctttca aaagtagttt tggcataatc agatatttca
     1621 tcatcaatca cttgtctacg atatttcgtt actaaaacaa ggtggtaata aagaagaaat
     1681 actgaatgat tatttgtatc taattccatg ttatatcaac tcatttcttg tatagactga
     1741 ttgtaacatg gaacaaaata aaaaggcaat acgccttagt tgtcggtctt cgagttacca
     1801 acggtaaccc tcataccgaa cggcattcat cacccaccta tagaggatgg gcga
//
LOCUS       DACGEU010000183         1812 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.190, whole genome shotgun sequence.
ACCESSION   DACGEU010000183 DACGEU010000000
VERSION     DACGEU010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1812)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1812)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1812
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.190"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            <1..341
                     /locus_tag="IXR40_002863"
     CDS             <1..341
                     /locus_tag="IXR40_002863"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362641.1"
                     /translation="LNSFIKDIEAKGEKLSVEEVEKRAVKHNLVCETREQVIKEIKSL
                     SEDMVKYQKVFNCYKKYTQESYVMPLNIQTISKNRIRRINKFDPSGNMKAPGNVLNEV
                     DESLKKYFTK"
     gene            624..697
                     /locus_tag="IXR40_002864"
     tRNA            624..697
                     /locus_tag="IXR40_002864"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:658..660,aa:Ile,seq:cat)
     gene            1243..>1812
                     /locus_tag="IXR40_002865"
     CDS             1243..>1812
                     /locus_tag="IXR40_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HAQ4362642.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNG"
BASE COUNT          627 a          284 c          329 g          572 t
ORIGIN      
        1 atttgaatag ttttattaaa gatattgaag ctaaaggtga aaagctttca gtggaagaag
       61 tagaaaaacg agctgtaaaa cataatttgg tttgcgagac aagggaacaa gtaattaaag
      121 aaataaaatc attatctgaa gatatggtaa aatatcagaa ggtgtttaat tgctacaaga
      181 aatatacaca agaatcctat gtaatgccac ttaatatcca aacgattagt aaaaatagaa
      241 ttagaagaat taacaagttt gatccttctg gaaatatgaa ggcacctgga aatgtcctca
      301 atgaagtaga tgaaagttta aaaaaatatt ttacaaagta aacgatattt ttgttgacat
      361 ttttctgttc gttagttacc atgtagttat agaaggacgt aagcgcctat ttttaatgta
      421 cacatcggga cgtatgcgcc cacatagaaa catagttgag agacatctat atggtgtctc
      481 tttttttatt aatatgcaaa aaagtctagt tttttcaata atatttatgt aataataaat
      541 tagccaccac aacaaagaat gaaacccatt attatctagt ctatgtccat tctttttgtt
      601 tgcagtagtt gtgatggctt tccgtactct tagctcagtt ggttagagca gacggctcat
      661 aaccgtccgg tcgtaggctc gagtcctaca gggtacatac tctaagtgat ttaaattgcg
      721 aataaaatat aaaaatgact ccccttttga ctcccccaag cagtatatgg atgtctctaa
      781 aagttgtttt tttagataat aaaaagctga taataagcga aaaacactta aaatcagctt
      841 taaaccctat tctcgaaatc cggcgaaccg gctaataccg gcgcgcaggt tcaaatcctg
      901 taccttcctt atatcaacga ttagaggttg tgaagaagct gtcctgcatc aagtaataag
      961 aacggccaaa caaaaatagc ttttcctatt ttttcgtttg attgggctta ttaccgcaga
     1021 tgcaagcttt tgaacaccgt ttgttcggaa taaggggctg tgacaagact tttgtcacag
     1081 ccccttattg ttgtactttt aacctacaat attttttgat tccccctgag tactattttt
     1141 tataaatgct agtaaatcaa tcttctttgg cctttttttg ataaaaaaaa tactagatgt
     1201 aagataaaag tgtaaaaacg atttgtttta ggaggggaaa cgatgtgtac cgcaatcact
     1261 tatgcaacga aagaccatta ttttggaagg aattttgatt atgagatgtc ttataatgaa
     1321 gtggtcacta ttactccaag aaattatcgt ttcgatttta gaaaggtaaa aaatttagat
     1381 aaacattatg caatgatagg aatagcagct ggggtatcca actatccact ctattatgag
     1441 gctacaaatg aaaaagggtt gagtatggca ggactgaatt ttcctggcaa tgctgattat
     1501 aaagaattac aagaaggaaa agataacgtt gcaccatttg agtttattcc atggatacta
     1561 gggcaatgct caaccataga cgaagctaaa gaattattgg ctactatcaa tctagtcaat
     1621 atcgatttta gtgaaaaact acccttgtca cctttacact ggttattagc tgataaagaa
     1681 aaatcgatag taattgaaag tatgaaagat ggacttcatt tatatgataa tcctgtcggt
     1741 gtgttgacaa ataatccgcc atttgattat caattattta atctgaacaa ttatcgctcg
     1801 ctatcaaatg ga
//
LOCUS       DACGEU010000184         1700 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.191, whole genome shotgun sequence.
ACCESSION   DACGEU010000184 DACGEU010000000
VERSION     DACGEU010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1700)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1700)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1700
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.191"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            524..1609
                     /gene="xerS"
                     /locus_tag="IXR40_002866"
     CDS             524..1609
                     /gene="xerS"
                     /locus_tag="IXR40_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HAQ4362643.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLENNPMDQVATITDKTTLAARAN
                     AIEKKLFLDEDTQNYLDYIANEYKKTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VVNINLEDLSLEKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRVQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHTSTNTTTLYTHIDNAATIDALNAL"
BASE COUNT          632 a          287 c          237 g          544 t
ORIGIN      
        1 ggcaggatcg tactttgttg atgattgaga tattgctaca tcaatctcag cagttaagat
       61 ttttttgaat tgttgcttga attttttctt tatctaaaaa aattgtatct ccaggatgca
      121 acccattttc tttaagaaat tccttttaaa ttgttaatac tactgagtgc cccacttctc
      181 tgaattttct ttaacttctc cctccccttt tttatttgta tatacattca tatacgcttg
      241 ttaatatcaa atcaaccgta gtctctctta tgtctaatta tatagaaaga ttgttctttc
      301 tatataattt agacaattta aaaaattaag attgcctcct tctgtttcct ttcctattca
      361 tgtataccat ttattttaaa ttattaaatc tatacctatt tatctgcttt tttgaaataa
      421 attaataaat ttcagagtat accaattgac aaaacactct ataattggta tagtccaatt
      481 atagagatac tcctctcccc tacttatcga aaggatgaat aacatgaaaa atacagaaat
      541 atatcaaaaa atagatacaa tcatacttca tatgcccgat tatataaaag attttgttca
      601 agatcgtgag gataaagatc aatcacctcg aactacttta gaatatctaa aaaattataa
      661 gctcttttat gaatggcttc tgagtgagtc tatcgttccc gatacttcaa tcacctcgat
      721 aagacagtta actgcctatg atctaaactt gtacaaatct catttgaaac gtcgcacaaa
      781 ggaaaatgta aaaaaagaga caacaaaaac taagctcaaa gataataata acttaggtct
      841 atctacttct actatcaata gaaatatcac agcattaaag gttctattta aatatctttc
      901 gaaaagttcc aataatcctt taggaaaacc atacttagaa aataatccta tggatcaagt
      961 agcaactatc acagataaaa ctacgttagc tgcccgtgca aacgcaatcg agaaaaaatt
     1021 atttctagac gaagatacac aaaattatct agattatatt gccaatgaat ataaaaaaac
     1081 tttgagcaaa cgagctttga tctattatca acgagatgta gaaagagacc tggcgatcaa
     1141 tgcattgatt ttaggatctg gattaagact ctccgaggtt gtaaatatta atttagagga
     1201 cctatcttta gaaaagaata atgtggtagt aactagaaaa ggaaataaga gagacgcagt
     1261 aaatatagca gcatttgcaa tggaatattt agctaattat ctagctattc ggaaagaacg
     1321 atacaaagta acagaaaacg aaaaagcttt atttctagca atttatcaag gagaagccaa
     1381 gcgtatatcc ggtattgcaa tcgaacggat ggtagcaaaa tattcaaaag gattcagagt
     1441 ccaagtcagt ccacataaat tacgtcatac tttggctact agactctatc aacagacaaa
     1501 ttcattggta ttaactgccc aacaattggg acatacaagt acaaatacaa caactttata
     1561 tactcatata gacaatgcag ctacaattga tgctttgaac gctttgtaaa tgtagtaaaa
     1621 aatagtataa taatgaagcc tgtctctaaa attagataaa agcccaactt taaaggcaag
     1681 cttcattatc atttttatat
//
LOCUS       DACGEU010000185         1675 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.192, whole genome shotgun sequence.
ACCESSION   DACGEU010000185 DACGEU010000000
VERSION     DACGEU010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1675)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1675)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1675
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.192"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..1421)
                     /locus_tag="IXR40_002867"
     CDS             complement(<1..1421)
                     /locus_tag="IXR40_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HAQ4362644.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLT"
BASE COUNT          473 a          364 c          262 g          576 t
ORIGIN      
        1 tctgttaacc acttttctag aattttcatc tttgaataaa acaacggtat ttggttttca
       61 tccagcctac tgtaattgat tctgattcca tttatatctt gcccaaaaag tagacttggt
      121 gcaattccaa gacccatatc tactactttt tctgctagtt cggggtctag ttttttccca
      181 tcccaagtaa tccaggcata gtaaccacct aaaattgaat gaagcttgaa aaacgattgt
      241 gaatctcccc aagcgcttat cagtcggctt ttttctttca acttttttct tacatcttgc
      301 attttcaaat caattgcttc attaaataca ttagccactg tgatttgtgt aaggatattc
      361 atcgaaaact ccatcatttc ttgcgcttga gctagttgcg agataaaagt ctcaggtcct
      421 atcacccaac cgattttcgt tgtttttcct aaaaccctag ataacgaacc gacgtataac
      481 acattatccg gatcaatcgt tcgtatagga aggacttctt cttggtttag aaatgaaaga
      541 tccgtaaata catcgtcttc aataattgga agccgatact gtcgacacaa ttctactagc
      601 ttttctcgtc gtttttgact catcactttt cctgtagggt tttgaaaatt cgggttgata
      661 agcactgctt tcaatttatt tttatggatc gattctttca gtttttctaa gtcgatccct
      721 tcttcatcca tcggtatccc aaataaacgc gttcctgaag ctttgaaaag aggtaatcgg
      781 taaaaaaaag aaggtgactc tacagctatc ccctctccag ctgaaagaat cgtttgtaaa
      841 atcaaaaaga ttgcttgctg accgccacca gtcacaagaa gctggttggg ggaaaatgcc
      901 aattcaaatt tactttccaa ataccgtttg attttgttac gtaacggagt atagcctaaa
      961 agatccattt ctttttcttc cgctaagatt tcttcaagag aataagaagg aaactcaaaa
     1021 ttcggcaaaa gctcatctgg catctcgcta gcgtataaat caagaaacga tgttttttgg
     1081 atctgctttg cttctcttat tttttgctca taccagtccg tctgctcata acgaggagag
     1141 atcatttgcc gccaatcgat tcttggaaca gcgaatttcc cccattcagt ctgattaaca
     1201 aaccatccgc tgccacgttt gctcgttagt accccaagct ccctaagctc ttccaatgca
     1261 tggacaacgg tggaacgatt cacaccaaaa agttgcccta gttttcgttc tgattcaagt
     1321 tgacttccag gattgatcct tccgttttcg atttctctca taatctgttc cataatttga
     1381 cgataaatcg gtccttgttt tttctctact ttttcccaca taagcttctc ttttctattg
     1441 tctatttttt cttttgattt taccgaattt acgagaaaaa agaaaaactt tttttgcaaa
     1501 acataaggga ctgtgacaaa aatcttatca cagtccctta ttctgaataa tgatgttcaa
     1561 aagcttgtat ctgcgataat aattccagcc aaacaaaaca tataaagaac tatttttgtt
     1621 tggctgttct tattacttaa tgcaggacaa ctttttcaca acatcctaat atttt
//
LOCUS       DACGEU010000186         1665 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.193, whole genome shotgun sequence.
ACCESSION   DACGEU010000186 DACGEU010000000
VERSION     DACGEU010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1665)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1665)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1665
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.193"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            132..506
                     /locus_tag="IXR40_002868"
     CDS             132..506
                     /locus_tag="IXR40_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HAQ4362645.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(620..1249)
                     /locus_tag="IXR40_002869"
     CDS             complement(620..1249)
                     /locus_tag="IXR40_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAQ4362646.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1383..1455)
                     /locus_tag="IXR40_002870"
     tRNA            complement(1383..1455)
                     /locus_tag="IXR40_002870"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1420..1422),aa:Thr,seq:ggt)
BASE COUNT          584 a          240 c          283 g          558 t
ORIGIN      
        1 tctacactct gagatgtaag aaatatcata agatatttct tacatctttt tgttttgagc
       61 aggactttag ataattttat taatatatgc tagcatgctt ttgtaagaaa aagaaagagg
      121 gcgtattagt tatgtatctt aaaattacgg aacaagcaca agaaagatta caaaaatata
      181 ttgatgaagg cgcaacagtt atattggatt tagatgatgg cgttggggaa tattctaaaa
      241 tgggtgtttg ctctttagat actagttttc gtttacttct tcttgataaa gaacagagaa
      301 aaaatgatta taaactccaa ttagatagtg atattgggga tgtttatata aaagattatt
      361 caaaaatgta catggatgaa catatgaccc tttctttaga tccacgtcta ggtgtattta
      421 ctcttgaaag cccaagtggt tctttagaca gtcatgttca attagtagat ctacgaccag
      481 aaaaattctc tggaataaaa caataacttt ctctctattg tccataaaac tagtctcaat
      541 caagctgtat tgaaaaaaca agacaacatt cttaccatgg taaataaaaa gacgacacat
      601 tttgtcgtct ttttttaaat taactatttt cgataaaaga tcgcatagct tgtgccatta
      661 tttctggctt ttctctattc aattcatgtt ttccgttttt aataaagagt agccggccat
      721 tcgttgaaag tttatataaa cgttttgctg ctggtttatt cgcatgatct ttggtaccgc
      781 ataaaatcaa tttaggaagt cgtgatgtac gaagctgttt tttgcagtct aatgtttcaa
      841 gtgaacgaag tagggtaagg gtttgttttt tagatagacc taatttttca aatatcttag
      901 aaggtacgca gtaaaaataa atattctgga aagtaagcaa taagcgatta ggagactcaa
      961 attgtggagc gactaaaaca acctttttta aatatggaga aggagttgca agatagttta
     1021 aagcaataac agcgcctaaa gataatccac ataaaataaa aggttccttt atctgattca
     1081 attgtacttc gatgtatttg gttaagtcgt ctaaagtagc agtgtctgtg ctgtttaaat
     1141 gattgaacaa tgaaagactt ttgcaagaat aactattggg tagataagag attacatctt
     1201 tccatgattg ttcgtcttgg cctagaccat gcaaaaaaac aattttcata ttgctctcct
     1261 ttttatagtt atcatataga ctttctttgt actattaaaa tataaacatt catttcttac
     1321 gtcataaaat aaaaaaacag cgcagacaca ttgttaaacc aacatgttgc actgtttaag
     1381 gaagccactt gccgggcttg aaccggcgac ctcttcctta ccatggaagc gctctaccag
     1441 ctgagctaaa gcggcattat cattaataca aataatagga taacgaatat taatgtattt
     1501 gtcaacagaa ttttttcgaa aaaatgtgtt tctctaatag gaaaacagat tttagaaaaa
     1561 ataaaaataa caaaaaatgc gaacggtttc tttgataata taataaaaaa attcaaaaaa
     1621 agtattgcgt tatttagaag aaattgatat tatattcatg tactt
//
LOCUS       DACGEU010000187         1648 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.194, whole genome shotgun sequence.
ACCESSION   DACGEU010000187 DACGEU010000000
VERSION     DACGEU010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1648)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1648)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1648
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.194"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            5..412
                     /locus_tag="IXR40_002871"
     CDS             5..412
                     /locus_tag="IXR40_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362647.1"
                     /translation="MLSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELTPLDRN
                     GIAIGNPTNDLTVTENYLIVSPLLARAASKTIRVTGTMIFDKVGWPSRPPQSRNWKEK
                     RNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
     gene            422..625
                     /locus_tag="IXR40_002872"
     CDS             422..625
                     /locus_tag="IXR40_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362648.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
     gene            836..1420
                     /locus_tag="IXR40_002873"
     CDS             836..1420
                     /locus_tag="IXR40_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAQ4362649.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
BASE COUNT          578 a          238 c          302 g          530 t
ORIGIN      
        1 gtttatttta tctttaggta ttttaactat tggaattagt gtaactggaa ctacaattcc
       61 tacatttgct gatagtacaa atgaaccaac tactgtagta gataataacc aagaattaac
      121 tcctttagat aggaacggaa tagccattgg taacccaact aacgacttaa ctgttactga
      181 aaattattta atagtttctc cattacttgc tcgagcagct tctaaaacga tacgagtgac
      241 aggaacgatg atttttgata aagttggttg gccttctaga cctcctcaat cacggaattg
      301 gaaagaaaaa agaaatggtt attggtacta tggaaaattg tatttacaaa gttataaatc
      361 agctggaaac aattggattg cgacttattc aggaacctta actagaaagt agggattttt
      421 tatgccagaa tttgtgaaca caccaaattt ttatcaagat agcgatattc taagtaaaat
      481 taatttaccg aaagaagaat cagctttaca agttcagcga actttacagg agacacaaaa
      541 aattcaaaaa tcaatttcta atctagaaga ttctgaagaa aaaagaaaaa aaagagacca
      601 aaaaacatat caaaaagaaa aataatgatt ttaaaaaaag agtgtctagt cgacattctt
      661 tttttctaat tgaaagtgtt cataaaatca cccatttctg gacactttct ttttttgctt
      721 tatttttcaa aaaaacaatt catttcatgt tcataaaccc ataacaatat ctatgttcag
      781 ttaaactata tggataaagt tatgttacaa taaaattaat gaaggagtga tttttttgaa
      841 aataggatac gcccgggtat ctactggttt acaaaatttg gatttacaag aagacagcct
      901 aaataaattt ggttgtgaaa aaatttttac tgatcatatg agtggggcaa aaagtaatcg
      961 accaggatta gaaatggcca ttgattttgt tcgctctggc gatacacttg tcgtttggcg
     1021 cttagatcgt ttaggtagaa atatggaaga tttgatttca atcgtcaatc gactgaatga
     1081 gcgtggtgtg agttttcata gtattcaaga aaatattacg atggacaaat caagttctac
     1141 aggacagctc atgtttcatt tgtttgcggc atttgcagaa tttgagcgta atttgatcct
     1201 ggaacgatcc gcagcaggac gagcagctgc tcgtgcaaga ggacggtttg gtggtcgtcc
     1261 tgaaaaattg tctgaacaag atttggaatt actgaagact ttagtggata gcggtacacc
     1321 tattaagact attgcggaac ggtggaacgt ctcaagaacc accatttatc gttatttggc
     1381 aaaaatggag gagaaaaatg gaaagacaaa ttctcattag tttttgtcat ttaatgctga
     1441 aaatttttgc catttatcta gaaaagtgac aatagtatga gaattttttg taagtgtcta
     1501 ctgataactt attctcaaat gttgtaagga ttttattcat ttgttaatat taaagaacgg
     1561 aactccaaaa aagtccgtac tctaatttgc agtctctcac tcttttagag tgagagtttt
     1621 tattagattt tcaaattaat tagtaaag
//
LOCUS       DACGEU010000188         1586 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.195, whole genome shotgun sequence.
ACCESSION   DACGEU010000188 DACGEU010000000
VERSION     DACGEU010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1586)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1586)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1586
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.195"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            76..1542
                     /locus_tag="IXR40_002874"
     CDS             76..1542
                     /locus_tag="IXR40_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HAQ4362650.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
BASE COUNT          441 a          291 c          332 g          522 t
ORIGIN      
        1 ataagttttt tagttaaatt tttcggtaaa gatgtataat attttctgaa aatttaaaga
       61 attggggtat agattatgga aaaacagcaa gacaagggct tcttcgggca gccgaaggga
      121 ttgtcaactt tgttcttcac tgagatgtgg gaacgattta gttattacgg tatgcgtgca
      181 ttacttatct attatatgta cgatacagtt gccaacgggg gacttggatt accacgagca
      241 acagcattag ctatcatgtc gatctacgga tctttgatct acatgtctag tatcgtcggc
      301 ggatgggtat ctgaccgagt gttaggagca aaacgcactg tattcttcgg tggagttttc
      361 attatgcttg gccacatcgt cttggcttta ccatttggtg taagtacatt gtttgtttcg
      421 atggcattga ttattatcgg aaccgccttt ttgaaaccaa atgtttctgg catggtcgga
      481 catctttatt caaagactga cttgcgaaga gatgcaggat tttcgatttt ttacatgggt
      541 gtcaacttag gggcattatt agcaccacta atcgttggta caatcggtca agaatataac
      601 tatcatttag ggttctcttt agctgctatt gggatgttct ttggattatt acaatacatc
      661 atccaaggac gcaagacatt agacggagtg ggtacaacac cgccgaatcc tttgacaact
      721 gaagaacgta aaggattcat ccgtaacttg atcatcgcac ttgttgttat cgctgcagta
      781 ttcggcgggg cacaactaac tggtcatctg acaattgact tttttgtcaa tacaatcagt
      841 gtattgggga ttatcttacc gttgtattac tttatcaaaa tgctgacttc aaaagatgta
      901 actgctgaag aaaaaccaag agtatgggct tatatcccat tattccttgc agcaatcatt
      961 ttctggtcat tacaagaaca aggttcatct atcttagctt tatttgctag tgaacgtaca
     1021 caatctacgc tatttggtgt aacgatccaa gcaagctggt atcaatcatt gaatccaatt
     1081 ttcatcttta ttctgacacc agtattcgta acgatgtgga cgaaacttgg tgaacgtcaa
     1141 ccatctacag tagtgaaatt ctctcttgga cttttatttg caggattatc gtacttgcta
     1201 ttgatgttgc cgggtatgct ttatggtaca agtggaaaag taagtccatt gtggttgttg
     1261 ggaagtttct tcatcgtggt tattgctgaa ttgtgtcttt caccagttgg tttgtctgtg
     1321 acaacaaaat tagcaccacg agcatttgaa tcacaaacaa tcgctatttg gttcttagct
     1381 gatgcttctt cacaagcaat caatgcacaa attgcacgct tctacacacc gggaacagaa
     1441 tctgcttact tcggtattat cggtgcagta gcaatcgtcg gtggtatctt gctatttact
     1501 gtgaaagaac caatcaaaaa actaatgggc tctattcatt aatcaatgaa cataaaaaca
     1561 ggaattgctt atttgcagca gttcct
//
LOCUS       DACGEU010000189         1447 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.196, whole genome shotgun sequence.
ACCESSION   DACGEU010000189 DACGEU010000000
VERSION     DACGEU010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1447)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1447)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1447
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.196"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(137..427)
                     /locus_tag="IXR40_002875"
     CDS             complement(137..427)
                     /locus_tag="IXR40_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362651.1"
                     /translation="MGEKKIKGAGILLVMSKALFLLPCTFMFIVLCYFKRRKKWCWID
                     VLLFLPFFPLIYFLEEIWDDMACDSAFLFSHSLGLMISLTIFAIVLFFLNKK"
     gene            complement(545..805)
                     /locus_tag="IXR40_002876"
     CDS             complement(545..805)
                     /locus_tag="IXR40_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362652.1"
                     /translation="MGVDHLIVLSKLLFWIPFIIMTSAFFYLFKRPNKYLLLSACPMI
                     YFIHKIRGFYYYDSGISLFCYEIGLLASAIFFIFVLEYFRKK"
     gene            complement(942..1355)
                     /locus_tag="IXR40_002877"
     CDS             complement(942..1355)
                     /locus_tag="IXR40_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HAQ4362653.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
BASE COUNT          531 a          238 c          214 g          464 t
ORIGIN      
        1 ttgttactat gaataacata ataagaaagt aaagtggatt gatttgagat ctttttatac
       61 ttcaaaaaag ataacaccca actttcaaaa atatgttttg gaagttggga caaacgagtt
      121 aatacatttt aatacattat tttttattca aaaaaaatag cacaatggca aagatcgtaa
      181 gagagatcat aagccccaat gaatgactaa aaagaaaagc agaatcacat gccatatcat
      241 cccatatttc ttcaagaaaa taaataagcg ggaaaaaggg aaggaatagt agaacatcga
      301 tccagcacca tttttttctt cttttgaaat aacataaaac aataaacatg aacgtgcagg
      361 gaagtaaaaa caaagcttta ctcataacta acaaaatacc agctcctttt atttttttct
      421 cccccacatt caaagagtaa caatggtatg tacttaataa tagaaaaatg gatcaacttg
      481 tatgaataac agctgaaaag atctgcacca aataaaaaac ttccagccaa aactgactgg
      541 aagtttattt ttttctgaaa tattctaaca caaatatgaa aaagatggcc gaagctaata
      601 agccgatttc gtagcaaaac aatgagatac cagagtcgta ataataaaat cctctaatct
      661 tatggataaa atagatcatc ggacaagcag ataagagtaa gtatttgtta ggccttttga
      721 ataagtaaaa gaaagcactg gtcattatga taaatggtat ccaaaacaaa agtttactta
      781 agacaatcaa atgatcaact cccatatttt ttaccaagag agatcataac atctttatcg
      841 taaaaacaaa atattttttt gctcattttg aaaatttaaa catactcgtt cttatccaaa
      901 tatataaaaa tcgcccctca ttcatcgaga ggcgataagt tctaatttaa ctcaattttt
      961 tttgtttctt ttggctgata agctgtttta ggtaatacca atttcagcac accgttttta
     1021 aaggttccag tgattttttc ttcatcaaca ttaggaagat agaatgaacg tttgtaagag
     1081 accgaatgtc tttctttccg tacatagttg ccatcttctt tatcttctgt atgggactca
     1141 tgattggcgg agatcgtcaa agtattatct gaatattcaa ctgtcgtgtc ttctttgtca
     1201 cagccaggca tatcagcagt tagtttgtat tctttttcat tttcgactaa atctactttt
     1261 ggataacttg aaacacctaa aaaatcattg aatgctggac taaacacgtc attgaaatca
     1321 gggaacatgt cgcgaatgct aggtacattt gccatttttg atcatccttt caataagtat
     1381 tttttattta tccctattta cgtaataact ctattttgaa aaaaatgcaa gtataatggt
     1441 tagcttt
//
LOCUS       DACGEU010000190         1424 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.197, whole genome shotgun sequence.
ACCESSION   DACGEU010000190 DACGEU010000000
VERSION     DACGEU010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.197"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(150..1337)
                     /locus_tag="IXR40_002878"
     CDS             complement(150..1337)
                     /locus_tag="IXR40_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HAQ4362654.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
BASE COUNT          414 a          309 c          249 g          452 t
ORIGIN      
        1 taaaagttca acctcatcaa aagcacaatg ttttgcgttg tgaacctaac tgccatgcct
       61 ttctttctga ggagagaggt caggagcagt agcgcagcga ctcttgatgt ctctcctcag
      121 aaagaagaga ctcgcacagg ttcatggtgc taaatgttat tcgaattaaa ttctaaatat
      181 tttcgtggag aagccagcca ctcagtgtct ttttccatca aaagtgttcc aattatccga
      241 gtgatggaat tgatatttgg aaaaatccga atcactcgtt ctctccggcg aatctcttcg
      301 ttcaaccgtt ccaacacatt ggttgtacga atccttcggc ggatattttc aggaaaagac
      361 aaaatttgaa tagcatcttc aaagccgttt tctaaaatgt cgcaagcagc acttaatttt
      421 gaatcacaac catatttttc caagaagtgc tcttttcttt cacgtgtcaa ttcaagttca
      481 gaggctttaa agatactctt caactcgtct tttacatcag aagaaacttt ctttggcagc
      541 ttatcaaaaa tatttctcaa aaagtgggct tggcatcttt gccagctcgc acctaaaaag
      601 ttcttgcgaa cagccttaac taaccctttg tgtgcatcag aaatgaccag ttttacaccg
      661 aacaaacctc gttgaacgaa cgattgaaaa acggtatccc aattatcttc cgattcgccg
      721 tcttgaacat caaaaccaag aatcgtacgt cgtccatcag aatcaatgcc gataccaata
      781 tatacacctt ttgagacaat acgatgattt tcccttactt tcatatacag ggcatcacac
      841 atgaaaaatg gatattccga gccttctagg ctccggtttc tccactcaaa aacaaatgga
      901 tccaactgtt tcatcagatt tgaaacgaat gatttagaaa cagtcgcacc atccgttagc
      961 agttcaactg ttttagttac tttgcgagtg gagacaccag aaatgaccat ttcaatcatg
     1021 gcagcgatca aagctttttc gcttcgctga tatctttcaa agatagtagg actaaactta
     1081 ccgtctctgg ttcgtggaac atgaagttct aacgtaccaa ttcgagttgt aaacgaacga
     1141 tcgtagtaac catttctttg tgattgccgt tcttctgaac gttcataggc atttgcctga
     1201 atatattgat ttcgttgttc ttccatcagc tgattaaaca tgatagtcat aagtgttttt
     1261 gcggtatcat tcgcaccgct ttcgtttata attgcttgaa tttcttcgct ttcaaaagta
     1321 aaatgtactt gagtcattga tatcagtcct attcgagtat gttttctgca aaaaacattg
     1381 tactcctaac tgagatcaat ggcttttttg atgcttcact ttta
//
LOCUS       DACGEU010000191         1367 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.198, whole genome shotgun sequence.
ACCESSION   DACGEU010000191 DACGEU010000000
VERSION     DACGEU010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1367)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1367)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1367
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.198"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            56..1351
                     /locus_tag="IXR40_002879"
     CDS             56..1351
                     /locus_tag="IXR40_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAQ4362655.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFSLATREA
                     VQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHS
                     QRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNLRQGYQ
                     LYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNALHYSYSNGP
                     LECLNNHIKVLKRNAYGFRNFYNFKLRIMIRHGKTFLTK"
BASE COUNT          432 a          272 c          262 g          401 t
ORIGIN      
        1 acaccctgaa atcctttaga attaatttgg ctaccaattc ataggaggat tcaagatgtc
       61 tcatactcag cttatcaaag ataccctaaa tattctagac ctaaatatct atttcgagga
      121 aaattgttta actaaagaaa aatacaaagg gcaaatttgc ttgatttaca aaggaactct
      181 tctgtacaag ccagaagagt gttcccattg tctttgtgtc gtcccctcta ggatcattcg
      241 ttgggggacg acaaccgttc ggttgttact gaatgatgtg tctgagtatc gcacttatct
      301 ggagctgaag aaacaacgat ttaaatgtaa gtcttgccaa agaacattcg tagcggatac
      361 ctctgttgct gaaaaacact gtttcattag tcaaaaagtt cgttggtctg tcattgctcg
      421 cttaaaagag aatacttcca tgacggaaat cgctcgtcag aaaaatattt ccacttcttc
      481 ggtctatcgt gtcatgaagc gattctaccg cccattgaat cctttcaaac agactttgcc
      541 aaaggtctta tgctttgatg aattcaaatc ggttcgaagt gttgccagtg caatgagttt
      601 tatcatgatg gacggacaaa gccatgcatt attggatatt gtcgaaaatc gacgcttgcc
      661 ttatttagaa cgctattttt ctcggttttc attagcgact cgtgaagccg ttcaattgat
      721 tgttattgat atgtatgcgc cttatgtttc gttggtgaaa aagcttttcc cgaatgctca
      781 gttgatcatc gatcgtttcc acatcgtcca acatattggc agaactttct tgaatcatcg
      841 agtgaaagaa accacggtac gacttaaagg aaattcccac tctcaacgag ggttagggaa
      901 aaaattgaag cgctattgga aactcctaca aaaagaagaa gcaaagttaa actatgaaaa
      961 acgggtttgg cgtgccagtt ttaaagatta tttgactgaa agtgagattg ccgatcgact
     1021 gttagctgct tgtcccaact tacgccaagg ctatcagtta taccaagaca ttctttatgc
     1081 ggtaaagaaa agagatcagt cactatttga ggattgttta actagagaca ttagcggtct
     1141 gccagaaacc tatacaacca ctttacgaac gtttaaaaag tttctgccac agatccaaaa
     1201 tgcgcttcac tacagctatt caaacggacc attggaatgc ttaaacaacc acatcaaagt
     1261 attaaaacgc aatgcgtacg gctttcgcaa cttttacaat ttcaaactac gaattatgat
     1321 tcgtcatggc aaaacatttt taaccaaata aacagaacag aaagagg
//
LOCUS       DACGEU010000192         1329 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.199, whole genome shotgun sequence.
ACCESSION   DACGEU010000192 DACGEU010000000
VERSION     DACGEU010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1329)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1329)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1329
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.199"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            57..197
                     /locus_tag="IXR40_002880"
     CDS             57..197
                     /locus_tag="IXR40_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAQ4362656.1"
                     /translation="MSDSIEKMTLKKLADELGVSKNTVRNQLVNSGFDLAQYKEKNAV
                     VN"
     gene            complement(534..950)
                     /locus_tag="IXR40_002881"
     CDS             complement(534..950)
                     /locus_tag="IXR40_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362657.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIERNPDINNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMSEIIAEFADLYLKDTGILIGTNSKVYQETKEKI
                     EKQLNPSKRNQPKNRQKETNQTFTSKNFDPTNFLKR"
     gene            complement(952..1233)
                     /locus_tag="IXR40_002882"
     CDS             complement(952..1233)
                     /locus_tag="IXR40_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362658.1"
                     /translation="MDILVRKIDSKVIAKIDKRCQELTNKTGKKWSRNRYLKVLIEND
                     FDHALMHYKKDQFDLLLEKFIAIQEKNTETLNEYVRTNNQLIETLIGGR"
BASE COUNT          373 a          186 c          241 g          529 t
ORIGIN      
        1 aaacgagaat tagatacatg gcttcaagga cttgatgtga cggaagtagg tgctgaatga
       61 gtgattcgat agaaaaaatg accctaaaaa aacttgctga tgaattgggt gtatcgaaaa
      121 atacggtgcg caatcaactg gtcaattcgg gatttgacct tgctcagtat aaagaaaaaa
      181 atgcagtggt caattgaccg aaatttatgt ctttgggttt tggggtttta aaacgaaaaa
      241 aagggggcga ttttcgcccc ctttgctcta tgtgaaaaat ttgttatact tattttatcc
      301 ttaaaacata ccaatctttt tcttatttag ctgctcgtac gagcagcttt ttttacgatt
      361 atgaattcaa atcatgtatt tataattttt ttgtttttat ctttttttct gttatttctt
      421 ctgaaattcg tttttttcat tcaattggtt actatcttat tgtaaatgtt gctattaaga
      481 tggtgatcct acccaaaaaa taaaccagga atttaaatct cctggtttat tttttatctt
      541 tttagaaaat ttgttgggtc gaaattttta gaagtaaatg tttgattggt ttctttttga
      601 cgattttttg gttgatttcg tttggaggga ttaagttgtt tttcaatttt ttctttcgtt
      661 tcttgataca ctttagaatt tgtgccaata agaatacctg tatcttttag atataaatca
      721 gcaaattctg caatgatttc ggacatgatg gaaatttctt ttcccatagc atttagtttg
      781 gcttggttgc tggtagtcgt agtattggta tcaggttcat aactcataca taaaaaacga
      841 atggcttccg agtaattgtt gatatctgga tttctttcga taatggaatc taaaacgtcc
      901 acgtgactgg gataaagggt aacgtgtttt tgaacagaag tttttctcat gttatcttcc
      961 tccgataagt gtttcaatga gttggttgtt tgtacgaaca tattcattca gcgtttcagt
     1021 atttttttct tgaatagcga taaatttttc gagtaataaa tcgaattgat ctttcttgta
     1081 atgcataagt gcgtggtcaa aatcgttttc gattaggact tttaagtagc gatttcgact
     1141 ccattttttg ccagttttat ttgtgagttc ttggcaacgt ttgtctattt ttgcaataac
     1201 ctttgaatcg atcttccgaa ctaaaatgtc catagaaaaa ctcctttcgc atttgtgtat
     1261 aatttatgta tatcatacga atatagtatt tgtatagctg ttttttgcta aaatactata
     1321 cataagcta
//
LOCUS       DACGEU010000193         1313 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.200, whole genome shotgun sequence.
ACCESSION   DACGEU010000193 DACGEU010000000
VERSION     DACGEU010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1313
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.200"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            200..742
                     /locus_tag="IXR40_002883"
     CDS             200..742
                     /locus_tag="IXR40_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362659.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            898..1272
                     /locus_tag="IXR40_002884"
     CDS             898..1272
                     /locus_tag="IXR40_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HAQ4362660.1"
                     /translation="MLSEKTDLENTEAFNKESVKDLRKLPTKDINGKDFTSKDFEKYD
                     LTMVNVFATWCTACVKEIPDLVEVQNEMKSKGVNIVGVVTDPVDDNGENKEAIEKSKL
                     IHEKTKASYPFLMPDVEWQHFF"
BASE COUNT          532 a          148 c          256 g          377 t
ORIGIN      
        1 attgatgaag cagatcccaa agggctgctt catcaatttt ttcgtaagtg tccgtacact
       61 tactgtgctt gctcatatat taatcgatca tatactaatc gtgtaagaac aactttaagc
      121 ataatactta tattgttata ccatagtttg gaaaaataaa aaattatatt tcatcaacgt
      181 ttcataaaag gtgtgtagaa tgttattgaa agtagctata aaatgctatt gtgtaaaaaa
      241 taaaggagga ataatttatg aaaaaatagt accaagagga gcatgcctat tacttgcatt
      301 atgtttgagc ttaagcgcag ttgggtgtca aaaaagtaat gaaaacaata aaataaaaga
      361 aggacaatcc ataagttctg aagaggaagg catgtcaatt aatgcaaatg gcaaaaatga
      421 aacttttaag ccatcagatt atacattgga ggcaaagaaa gaatatgttt atgaatattt
      481 agggcttaaa tttaaactct cagacaaatt tagaaattat atagctgata aaaagatagc
      541 gatgttagat gatcaaagtc ctatagataa agaactaaag tatgctattt tgacatttga
      601 gaaaatgaca gaagaacaaa agaatgcagt tatagaaaag atgggcgatg gatataaaaa
      661 ttggcaaaat gagcttgaaa gaattgggac tattggtata tttgaaaaaa atacatcaga
      721 agaaaaaaat ctaaaattat aaaatgtgat actcatacta aaataggagt ttcaagtgat
      781 ggaaaatacg attgctattt aagcacaaat agcggagctg aaagtaatct tctggatgaa
      841 ttaaaaagaa ctgagattca aattatagat aaaaaagaac gtcctaaaaa tggttttgtg
      901 ctatcagaaa aaactgattt agaaaataca gaagcattta acaaagaatc ggttaaagat
      961 ttacgtaaac taccaacaaa ggacataaat ggcaaggatt ttacaagtaa agattttgag
     1021 aagtatgatc ttactatggt aaatgtattt gcaacttggt gtacagcttg tgtaaaggaa
     1081 attcctgatt tggttgaggt tcagaatgaa atgaaaagca agggtgtaaa tatcgttgga
     1141 gttgttacag atcctgttga tgataacggt gaaaacaagg aagcaattga aaagtcaaag
     1201 ttaatacatg aaaagacaaa ggcttcatat cctttcttaa tgccagatgt ggaatggcaa
     1261 cacttttttt gacaaaaatt ataaggtgtt gtgaatgctg cggtgttatg gct
//
LOCUS       DACGEU010000194         1267 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.201, whole genome shotgun sequence.
ACCESSION   DACGEU010000194 DACGEU010000000
VERSION     DACGEU010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1267)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1267)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1267
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.201"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            <1..722
                     /locus_tag="IXR40_002885"
     CDS             <1..722
                     /locus_tag="IXR40_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylneuraminate synthase"
                     /protein_id="HAQ4362661.1"
                     /translation="FLSTPFDEESADFLKQIGVQGFKIGSGDLTNLPFLRKIDMYGLP
                     VLLSTGMADIHEVSEAVDCFIDSPVTILHCTSNYPASSEDINLLAINTLKEMFGIPVG
                     YSDHSLGYDVGICAVAMGAKVIEKHFTLDKELPGPDHKASLDPQEFADFVKHIRNTEI
                     FLGDGVKRAMPSELSTKEVSRKSLVVTENLNVGDILTEKSLTIKRPGNGIAPKFLYQY
                     IGKKVKRPISADSVLLEEDVE"
     gene            719..>1267
                     /gene="neuC"
                     /locus_tag="IXR40_002886"
     CDS             719..>1267
                     /gene="neuC"
                     /locus_tag="IXR40_002886"
                     /EC_number="3.2.1.183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (hydrolyzing)"
                     /protein_id="HAQ4362662.1"
                     /translation="MKKILIVSGTRADYGIYKPVAENLLQDNWDVSFVVSGMHLSHKY
                     GFTKELILADGFRISGEVQSLFLENNKGNMARSVALEINGFTNIFEQTSPDFVLLLGD
                     RGEMLAAAIACLYLGIKTAHIHGGEVSGTVDESIRHAITKIASVHFAATEKSKERLIK
                     MGEDSWRVFPVGAPRIDTILNNR"
BASE COUNT          421 a          167 c          272 g          407 t
ORIGIN      
        1 attttttgtc tactcctttt gatgaagaaa gtgcagactt tctaaaacaa attggtgtac
       61 aaggatttaa aattggctca ggagatttaa caaatttacc ttttcttaga aaaatagata
      121 tgtatgggtt gccagtttta ttatctacag gtatggctga tattcatgag gtcagtgagg
      181 ctgtagattg tttcatagat agtccagtta ctattttaca ttgtacttca aattatccgg
      241 ctagttctga agatattaat ttattggcga ttaacacatt aaaagaaatg ttcgggatac
      301 ccgttgggta ctccgatcat tcattgggat atgatgttgg tatttgtgct gttgcgatgg
      361 gtgctaaggt aattgagaaa cattttacct tggataagga actacctggt ccagatcata
      421 aagcttcttt agatcctcag gaatttgcag attttgtaaa gcatattaga aacactgaaa
      481 tatttttagg tgatggtgtt aagcgagcaa tgccttctga acttagtaca aaagaagtat
      541 caagaaaaag cctagtggtc actgagaatt taaatgtggg agatattctt acagagaaat
      601 ctcttacaat aaaacgtcct ggaaatggaa tagctcctaa gtttttatat caatatattg
      661 gcaaaaaagt taaaagacca ataagtgcag atagtgttct gcttgaggaa gatgttgaat
      721 gaaaaaaata cttatagtaa gtggaacacg agctgattat ggaatatata aacctgttgc
      781 tgagaattta ctacaagata attgggatgt atcatttgtt gtttctggaa tgcatttatc
      841 ccataaatat ggatttacta aagaattgat cttagctgac ggatttagaa ttagtggaga
      901 agttcaaagt ttgtttttag agaacaataa gggaaacatg gctcggtctg tggcattaga
      961 gataaatggt ttcacaaata tatttgaaca aactagccct gattttgtat tattactagg
     1021 ggatagagga gaaatgttgg cagctgcgat agcttgtttg tatcttggaa tcaaaacagc
     1081 acatattcac ggaggcgaag tgtctggtac tgtagatgaa tcaataagac atgccataac
     1141 gaaaatagca tctgttcatt ttgctgctac ggaaaaaagc aaagagcgtt taataaaaat
     1201 gggggaagat tcttggagag tttttcccgt cggagctcct agaatagata ctattttaaa
     1261 taataga
//
LOCUS       DACGEU010000195         1243 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.202, whole genome shotgun sequence.
ACCESSION   DACGEU010000195 DACGEU010000000
VERSION     DACGEU010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1243)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1243)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1243
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.202"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            36..446
                     /locus_tag="IXR40_002887"
     CDS             36..446
                     /locus_tag="IXR40_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HAQ4362663.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
     gene            460..816
                     /locus_tag="IXR40_002888"
     CDS             460..816
                     /locus_tag="IXR40_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="HAQ4362664.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
BASE COUNT          449 a          177 c          235 g          382 t
ORIGIN      
        1 gtagaattgg attataatta aaaaggagtg agaaaatgat aaaagtatat acttcgccta
       61 gctgtacttc ctgtagaaaa gcaagagcat ggttgcaagc gaatcaactt gaatttgaag
      121 agaagaatat ttttgccgaa ccgttaacag aaagtgagat caaaaagatc ttggcagcga
      181 ctgaaggagg agttcaagat attatttcca ctcggtcgaa aatttacgaa aagctgggca
      241 tagattttaa cgaattaact ttaaagcaaa tgatcgtctt attcaaagaa tatccttcat
      301 tattgagacg acctattttg attgatgaaa aaagaatact aatcggattt aatgaagatg
      361 agatccggtc atttgtccct cgtgaaattc gatgtgttgc cagaaatctg atctatttac
      421 aaaacaataa catcttaaat tcatagggag ggagccttcg tggaagtgaa agtctatgga
      481 tcagcgcact gtgtaacaag tctgaaggcg aaacaatggt tagaacacca tcaattgcct
      541 tatcaatttg ttgacttaga agaacgcgat ttaagtacag aagaagcaga agaattatgc
      601 agttttgaag aagtgcaagc agaacagcta tttgcgactt ggtctgaggc ttttcacaac
      661 attgcgattg acctttcctg tgtaggaaaa aaacaactga tttttttatg cacacaacat
      721 accaatctcc tcagacgtcc tttgattatt atcgatgaag ttctatttat tggatacaat
      781 gagcagttga tggaacagct tatcttaaat aaatagactt taactgtttt aatcaagtca
      841 ctgagcattt catacagttg taacagtcga acacttagca tcaagcgtgt tatgtgttct
      901 ttttttgact ttatttttct actatagaga catgctcaat ttatgtggtc aaaattcaaa
      961 tctaggtggg gatatagagt taaaaatata ttgacatgtg taaatttaca tgatatattc
     1021 atttctgttg ttttaagtag caaagcaata aaatagtatt ttaaaaaaca tataaaatag
     1081 ttgttgacat gttagaaatg acatgataag ataactgagt tgttaaaaaa gaaccacttg
     1141 tgaagcttga ttctatcgaa aaaaacttca aaaaagttct tgacaaataa caaatgataa
     1201 gttatgataa atgagttgct gtaagatttc gaaaaacgaa atc
//
LOCUS       DACGEU010000196         1215 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.203, whole genome shotgun sequence.
ACCESSION   DACGEU010000196 DACGEU010000000
VERSION     DACGEU010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1215)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1215)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1215
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.203"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            414..947
                     /locus_tag="IXR40_002889"
     CDS             414..947
                     /locus_tag="IXR40_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HAQ4362665.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
BASE COUNT          389 a          226 c          225 g          375 t
ORIGIN      
        1 cttattaccg cagatgcaag cttttgaaca ccgtttattg agaagttgtg aaatcagcgt
       61 cctgacctga gtattagaga aacaaatggc aaaatagttc ctcatatttt gctatttttt
      121 gagctaatac cgagggtcag ctgattgaac accgtttagt ggagaagttg tgaaaaagtc
      181 gcctactttc gagtcgtaag aaattttttt gaaaatggtt cctcacaact ttgcataaat
      241 ttgacttaat accgagaagt catgatcccc atctaactcc aaatcacaag gaatgagttc
      301 aaaaactagc ttttctcaac aaatattaca taaaaaattc tatgtttttt gttaaattta
      361 tttgcttttt tcaaaagtat gttacagtaa tttcccaagg aggttttaca gaaatgaatt
      421 ttgttgccat ggattttgaa actgccaatc atcagcctta tagtgcttgt tctcttgcgc
      481 tagtcatggt aaaaaatagc cagatcgttg atgaattcta tacattgata cagcctgaga
      541 ctcctttttt ctggcgaaat gtccaaattc acggaatcca tcaagaagac gtacgcaatg
      601 cgccgaaatt cccagaagtc tggcaaacta tccaaccata ttttcaaaaa aatcgtttag
      661 tcgttgcaca taatgctgct tttgatacaa aggtcttagc gggatgctta gattattatc
      721 atcttgaaca gcctaattat ctttctttat gtacagtgaa aagtagccgt cgcctgtttc
      781 ctgaatttcc aaatcatcga ttgaacactg tgtgcgaaaa tttgaacatc caattagatc
      841 atcaccatga tgcattggaa gatagtcgtg catgtgcgga aatcctgctt tatcaagaaa
      901 aaaaattcgg gacagatcca ttgaaaaaac ttgtgactat aaagtaaaag aatacttatg
      961 aaacacacaa agaggtcgtg agcctgccgt ttcactccga gtcacaagga gcaatttcaa
     1021 aaaatagctt ctcatgttta ttaaatattg tgactggtga ccgaggagct ggcaggagaa
     1081 caccgtttat tggagaggtt gtgaaaaagc tgttctgcat caagtaataa gaacagccaa
     1141 acaaaaatag cttctcatat ttttcatttg gttggactta ttaccgcaga tgcaagcttt
     1201 tggacaccgt ttacc
//
LOCUS       DACGEU010000197         1210 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.204, whole genome shotgun sequence.
ACCESSION   DACGEU010000197 DACGEU010000000
VERSION     DACGEU010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1210)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1210)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1210
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.204"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(360..433)
                     /locus_tag="IXR40_002890"
     tRNA            complement(360..433)
                     /locus_tag="IXR40_002890"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(397..399),aa:Ile,seq:cat)
BASE COUNT          440 a          190 c          188 g          392 t
ORIGIN      
        1 ccactccaat tataagtctt tttcccatta ttttttacag ttatatggta tgctttttaa
       61 tggcttcaaa tataaaagag tttaaagcgt aacacactta tggggaagtg gtttttgggg
      121 aacgctttaa actcttcttt attattatct cacaatataa cccaaatgtc tttccattta
      181 aaaatcaaag taaaactttt caaatataca gaagtataac tatgtgaaac atcctttcat
      241 taatccataa aaggatacat aaaaaagcca ctcatttgag tggcaatgaa gaaaagcttt
      301 agcttgtata atactcttca aaaaattcta acacagaacg attcaattgg ctacattaat
      361 gtaccctgta ggactcgaac ctacgaccgg acggttatga gccgtctgct ctgaccaact
      421 gagctaaggg tagtggttgt tgccacataa agccataaac aatcaaccag tagaatgcgt
      481 ggcaacaaac ctgttatcgc atatcttgga gtgtgactat ttatgagtga tagtgaagat
      541 atgcgtctcc atatatgtat ggttgagaca gataaacatg tatgaaaaac gttgttaaat
      601 caacgttttt ttattttggt caaggagaga aaagtagaga aatacaaaat tttttgcatt
      661 gattttgcat tcaaaaaaac attcaaacat ttagaaatcc ccaatacgta ttcaggaaaa
      721 tctattttaa ggtttacaaa aagaactttt gttcgtacac tctttttgag gtgaactttt
      781 atgctgatgg aaggaaaaac acaattatgg tttaagcatg ttccttcaaa taagtttttt
      841 aattataaac tctagagaaa ttaattcatc ctaacataaa ataattgttc actcaaaagt
      901 ttttctagaa caattaaaac agcaggcttc acattcgcta tacatttgta agaagtaata
      961 attcctgtac taaaaggcat aattgcttta attatttttt gacttctctt caaacacaag
     1021 aagtagttgt gtaataattg cagaaataag gattccaata atagatataa aatttgacat
     1081 ggaaacgtct ataacattaa aagaataaag tgttgaagaa agtaaactga ttgaaataac
     1141 ccctccgtaa aaaatagtct gtgaatatac ccactttttt tcagaagacg tacttcgttt
     1201 ggttctaaaa
//
LOCUS       DACGEU010000198         1195 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.205, whole genome shotgun sequence.
ACCESSION   DACGEU010000198 DACGEU010000000
VERSION     DACGEU010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1195)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1195)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1195
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.205"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            <1..1076
                     /locus_tag="IXR40_002891"
     CDS             <1..1076
                     /locus_tag="IXR40_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAQ4362666.1"
                     /translation="VIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFSR
                     MFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQHF
                     LENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGKG
                     RFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQV
                     IVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQS
                     QNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKRALVLTARKF
                     TRLVDTLLRKHQLYTPPRSVIEK"
BASE COUNT          418 a          234 c          211 g          332 t
ORIGIN      
        1 ttgtgattgg catggagtca acgtccatgt acagcttcca tccttccatg ttttttcatg
       61 aagatgagaa actaaagaag ctcaacacac ttgtaacgat tgaaaatcct tttcgggtga
      121 aacaatttag tcgcatgttt gatgagaata aaactgatcg aaacgatgca ttaagaatcg
      181 ctgatttctt gcgtattcaa cgattcacaa cttcccctat caaagaagag aaatacatgg
      241 ccttacagcg tttaacacgt actcgctatc aacttattaa gcaattgatt cgtacaaagc
      301 aacattttct tgaaaatcta acgtacaaat gtaatacgct tgctcgagaa atgcgagacg
      361 aatcgacgag tctttttagt gcaaccctca tttcactcat gacggaagat ttcacattgg
      421 atgaacttgc tgagcttcct ttagaagctt tctgtgattt acttcaagaa aaaggaaaag
      481 gccgtttcaa gcaaccagaa aaaatcgcta aagcaattca acgtgcaatt accatgagtt
      541 accgcctagg tgctcttgca caagaatcaa ttaatgttgt tttaagtgtt ctcgtacgag
      601 aaatacgagc acttgaaaaa aatatcaaag aattagataa agccatcgaa caagtaattg
      661 ttgtcattcc agaatatcaa tgcttaacca gtattccagg cgttggtaaa gtctatgctg
      721 ccggtttaat cgctgaaatt ggtcaaatcg aaagatttga agatcagaca aaattggcaa
      781 aatacgctgg attaagttgg aaagtgaacc aatctggaaa ctatcagtcg caaaatacac
      841 ctctgacaaa acaaggaaat cgatatttta gatactactt agttgaagct gccaactctg
      901 taaaaaatta tcttcctgaa tacaaagctt tttatcaaag taaatataag gaggttccaa
      961 agcatcaaca caaacgtgca ctcgtcctaa ccgcaagaaa atttacgcgt ctggtggata
     1021 cgctactacg taaacaccaa ctctatacgc caccaaggag tgtgatagag aaataacaat
     1081 ccgttattga cgcaaatcct tgaatcaacc cgaaaaaaat ttgattttga tcgggtctag
     1141 tttcgtgcgc ttcaaaacat attactcaat aaagaaaatc ttaaatttca tcttg
//
LOCUS       DACGEU010000199         1188 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.206, whole genome shotgun sequence.
ACCESSION   DACGEU010000199 DACGEU010000000
VERSION     DACGEU010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1188)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1188)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1188
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.206"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(1..254)
                     /locus_tag="IXR40_002892"
                     /pseudo
     CDS             complement(1..254)
                     /locus_tag="IXR40_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
     gene            complement(286..447)
                     /locus_tag="IXR40_002893"
     CDS             complement(286..447)
                     /locus_tag="IXR40_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362667.1"
                     /translation="MAYMVARTQKHKVGSLNGLQNHVDRKTKNHTNKDIDITKSGSVA
                     KFSKKSILV"
     gene            complement(771..1103)
                     /locus_tag="IXR40_002894"
     CDS             complement(771..1103)
                     /locus_tag="IXR40_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362668.1"
                     /translation="MNNREILAKEMADLKAKEAKIRAKRKQIRQKEMISLAKLYCKKE
                     GFKTPAEALDFLESNKRNHSVNDEVLVSLRKFADGLVWQENGAYWRTNDVKGLTQFMA
                     QFRSENVN"
BASE COUNT          346 a          249 c          156 g          437 t
ORIGIN      
        1 gtcccttaat tttgatatag gtttcgtcca ttttccatga atagaaggat tgtctatttt
       61 tcttcttcca aagataatcg aggactttgc tgtactcttg cacccaacga taaatcgtag
      121 tatgacaaac atttattcca cgatcatata acaattcctg aacttcacga tagcttagat
      181 tgtaacgcag gtagtaacta acagcgacaa taatgacgtc attttttgaa ttgtttgcct
      241 ttaaaatgat tcattactct atcctctctg tcttttttct caattttaca ctaaaataga
      301 ttttttggaa aactttgcaa cagaaccact tttcgtaata tcaatgtctt tattcgtatg
      361 atttttcgtt ttacgatcta catgattttg aagtccattt aacgacccaa ctttatgctt
      421 ttgtgttcgt gccaccatat aggccataac tgtgtacttc ctttcgttaa aattattgcg
      481 agaatcacaa gctaaattcg gaaaaacctc catgtaaggt ataacttact agacttatac
      541 tgcgtaaagt ctgtaagctc tgccgagggc tatatcggct taacagccga tgagaaactc
      601 cgtttctctc aaacgaaaaa gcgaacgaaa aacgactgcc ttcgcattcc ttttttacgt
      661 ccttttttcg ttcaaaacca ttggcttttt gcgtcattgt tttcacaatt tttattccgc
      721 aaaaaaccaa aagtgaaaag tattgctttt cacttcaacc cctcctcaat ttagttcaca
      781 ttttctgaac gaaattgtgc cataaattga gtcaaaccct taacatcatt cgtacgccaa
      841 tatgcaccat tttcttgcca aactaatcca tctgcaaatt ttcttagcga tactaaaacc
      901 tcatcattta ctgaatgatt tcttttattt gattccaaaa aatctaatgc ttcagcaggt
      961 gtcttaaagc cttccttttt acaatataat ttcgctaaag aaatcatttc tttctgtcta
     1021 atctgttttc gtttcgctct aatcttcgct tcttttgctt tcaaatccgc catttctttt
     1081 gccaatattt ctctattgtt cattttgatt cctcctaaaa ataaggcata tttctagttt
     1141 aaaatattta ttttacgaat agaggatttg aacaacgaat gacacaaa
//
LOCUS       DACGEU010000200         1159 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.207, whole genome shotgun sequence.
ACCESSION   DACGEU010000200 DACGEU010000000
VERSION     DACGEU010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1159)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1159)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1159
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.207"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            16..276
                     /locus_tag="IXR40_002895"
     CDS             16..276
                     /locus_tag="IXR40_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362669.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVVGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(638..877)
                     /locus_tag="IXR40_002896"
     CDS             complement(638..877)
                     /locus_tag="IXR40_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362670.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
BASE COUNT          408 a          163 c          217 g          371 t
ORIGIN      
        1 aaggatggat gaaatatgaa taacgaaact atcattttag gaaaaaaata tatttgccaa
       61 cctattggct tgaaacaaaa agtggttgga gaagtaatca gtaaattaga aaattgtgtt
      121 gtgatctgcg tagacgaata tcatgacgtc gatcgcaatg aaatattaga aaaatgcgga
      181 aaagtagtgg caaaatatac tcacgtttat gagttggaaa caacagaata tctatataac
      241 tatagcaaca aatatgaaca tactttagtt tcataaagat ttaaataaag tgccttcaaa
      301 agcgagaaga ccaagctttt gaaggcactt tatttagttg gcagtgattg ttcatgattt
      361 ttgatttatt caaaaggttc gcctagagaa tctgtctctg taacgaggcc tggtggagaa
      421 actcgataaa aacctatact gccagaactg tcctattttc ggatagacaa actagtagtt
      481 ttaaaaagat catccgatcc aatcatttca aaaaatgcaa aactgatatc aggatcattt
      541 agctcaggct tgttatcgta aagcatttgt aaaggttgca tttagttagg agtaaacgcg
      601 aaactatcat cattatttgc tgaagaagat gaagaagcta attcagagtt tgtttgaaat
      661 aaaggagacg tgctgacagt ttctttaccc tgttttttgc agaggtagaa acttttatat
      721 cggaagtttc taccggagaa tttttctcat ttgtagaaat tgttgaatcg atactattcg
      781 aaatttgcgt atctgaaggt atgttctttg atgcagaagt cccacaagca gtaagtaaca
      841 ataaatttga taaactgata aacagaattc ttttcattat gtacacactc cttatagtat
      901 cgtttagcat acacctatgc tcagtattag gcaaaatcaa tgcaaaacta tcaagtcttt
      961 tatagtatct attagtctta gtaatacata tatggagagg gtgatatccc agttcaaacc
     1021 agatacattg gttaccatct gtattaacga ttatgcctct aaacgctttt tttatgaaaa
     1081 aatttataag tgaaaacgta ggtatgatat tatctagagg taattttttt gggtatttaa
     1141 atagttgcta ggaggatag
//
LOCUS       DACGEU010000201         1157 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.208, whole genome shotgun sequence.
ACCESSION   DACGEU010000201 DACGEU010000000
VERSION     DACGEU010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1157
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.208"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            237..>1157
                     /locus_tag="IXR40_002897"
     CDS             237..>1157
                     /locus_tag="IXR40_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HAQ4362671.1"
                     /translation="MSKRGTIINEWEKLNRISNRRLNAQTMCTPLKMQWSIDRITIVG
                     TLRENIYYHTPHDVLILDFEQLMRLNEGNGYLKAVGNNGWQLLDQHEENIAYIEILKF
                     QEGKGRIDFNPNKISQFLAGSMKNFIHDLFLEPHFSRADIACDIIDVPDDFITQYRVV
                     DPVSFKPIYGRSGKLETAYWGSRASERQIRMYNKKLEQERKRKVVPKEIDTWWRLELQ
                     LRRGKATDWHAMVHESLDSFASPHYLPEDVKVTDRMMITALITEHSYWGQIHRNSKYK
                     YRELLKQESQNDELTNHLRETFSESADDLKR"
BASE COUNT          398 a          183 c          249 g          327 t
ORIGIN      
        1 aggagtgcta taatcaaaga aaacgagaaa aaagagcaaa ataaaagccg aacggtgttg
       61 gaagcaccct tcggctaatt acggaaacta ctcacctagt tccgtaactc aaattcatta
      121 tacgaatatt tttaggtttc ttcaagctag agatttttgg atatggattt ttagagttac
      181 gtgaactctg gaaattcttt ccaaaaatct cttttttctt tgaggaggaa caaaatttga
      241 gtaaacgtgg cacgatcata aatgagtggg aaaaacttaa ccgcatatct aacaggcggt
      301 taaatgcaca aactatgtgc acccccttaa aaatgcaatg gtcaattgac cgaattacca
      361 ttgttggtac attaagggaa aatatttatt atcacactcc ccatgatgtg ttgattttag
      421 attttgaaca gcttatgcgt ctaaacgaag gtaacggata tttaaaagcg gttggaaata
      481 atggctggca attactagac caacatgagg aaaatatagc ttatattgag attcttaagt
      541 ttcaagaggg aaaagggcgg attgacttta accccaataa aattagccaa tttctggcgg
      601 gctcgatgaa gaactttatc catgatttat ttttagaacc acatttctca cgtgcagata
      661 ttgcttgtga cattattgac gtgccagatg atttcattac ccaatatcgg gtggttgatc
      721 ctgtttcttt caaaccaatt tacggtcggt ctgggaaact ggaaacagca tattggggaa
      781 gtcgtgctag tgaacgacag attcggatgt ataacaaaaa attggaacaa gaaagaaaac
      841 ggaaagttgt tccgaaagaa atcgatactt ggtggcgact agaattgcaa ttgcgaaggg
      901 ggaaagcaac tgattggcat gcaatggttc atgaaagttt agatagcttt gcaagtcctc
      961 actatttgcc agaagatgtg aaagtaactg acagaatgat gattactgct cttataacgg
     1021 aacatagtta ctgggggcaa attcatagaa attcaaaata taaatatcgt gaattgttaa
     1081 agcaagaaag tcaaaatgat gagttgacga atcatttgcg agaaacattt tcggagtcgg
     1141 cagatgattt gaaacga
//
LOCUS       DACGEU010000202         1137 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.209, whole genome shotgun sequence.
ACCESSION   DACGEU010000202 DACGEU010000000
VERSION     DACGEU010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1137)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1137)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1137
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.209"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            <1..762
                     /locus_tag="IXR40_002898"
     CDS             <1..762
                     /locus_tag="IXR40_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HAQ4362672.1"
                     /translation="LSSSRGAQVVICSFLVLFLLLFANSKFRKSIREVLPVKIKWMVS
                     ILLVLLVYFSFGTNYAKDFLATIPVSIDRKVEVIESNESDKTPLPEKEVILQHSSDNS
                     EISAGRFTIWKAALKVIRPTLLFGYGETDFYGNSDAKFLKKVDLDTTDVNELKRAHGN
                     MHNGFLQVLVSSGIIAFICIYAFYVLNIFSLLKTFFRSKVNYAFLGIVLIFILSIFID
                     EMVEAHVLFNKRDVISIVFWYYLGSISYLYLKKEN"
     gene            764..>1137
                     /locus_tag="IXR40_002899"
     CDS             764..>1137
                     /locus_tag="IXR40_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362673.1"
                     /translation="MKTAFIAWTPLHLINILNVYQNFYRESKGDLFIYSEFENARRYS
                     ERIKELGLFNDVVFVNHRKIGSSFKRKINLLTNHNQFFSDDLSVYDEIFIQGENYFTK
                     ILFSNVYKKNPDVKLNYIEDGLG"
BASE COUNT          377 a          137 c          195 g          428 t
ORIGIN      
        1 ctttcttcgt ctagaggtgc ccaggtagta atttgttctt ttttagtatt atttcttttg
       61 ttgtttgcca attcaaaatt tagaaagagc attagagaag tactacctgt aaaaatcaaa
      121 tggatggtaa gcatattatt agttctattg gtatattttt cttttggtac taattatgct
      181 aaggattttt tagcaacaat tcctgtatcg attgatagaa aagtagaagt tatagagtca
      241 aatgaatcag ataaaactcc acttccagaa aaagaagtaa tattacagca ttctagtgat
      301 aactccgaaa tttcagctgg tcgttttacg atttggaaag ctgcgcttaa agttataaga
      361 ccaactttgt tatttggtta tggagagacc gatttctatg ggaatagcga tgcaaaattt
      421 ttgaaaaaag tagatcttga tactacagat gtgaatgaac taaaaagagc acatggaaac
      481 atgcataatg gatttcttca agtacttgta tcaagtggta taattgcttt tatatgtatc
      541 tatgctttct atgtgttaaa tatctttagt ttactcaaaa cattttttag aagtaaagtg
      601 aattatgcgt ttcttggtat tgttttaatt tttatactat ctatttttat agatgaaatg
      661 gtggaggctc atgtactttt caataagcgc gatgtcattt caattgtttt ctggtattat
      721 ttgggaagca tttcttactt gtatttaaaa aaggagaatt aatatgaaga cagctttcat
      781 tgcttggact cctttacatt tgattaatat attaaatgtt tatcaaaatt tttaccgaga
      841 atcaaaagga gatttattta tttattctga atttgaaaac gctagaagat atagtgagcg
      901 tataaaagaa ttagggctat ttaatgatgt tgtttttgtg aatcaccgga aaatcggttc
      961 ttcctttaaa cgtaaaatta acttgttaac taaccataat caatttttct cggatgattt
     1021 atccgtttat gatgaaattt ttatacaggg ggaaaattat ttcacaaaaa tacttttctc
     1081 caatgtttac aaaaaaaatc cagatgtaaa actaaattat atagaagatg gtttggg
//
LOCUS       DACGEU010000203         1103 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.210, whole genome shotgun sequence.
ACCESSION   DACGEU010000203 DACGEU010000000
VERSION     DACGEU010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1103)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1103)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1103
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.210"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            3..1085
                     /locus_tag="IXR40_002900"
     CDS             3..1085
                     /locus_tag="IXR40_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017414133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAQ4362674.1"
                     /translation="MNDDGSRKKVEKVGGDTRPEAEAALRKVLSDIDETGQYFLGTDT
                     RVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKLTDLSPALLQNFINAE
                     FKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPKYEARPTTKKDLKIIS
                     LEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVDFSNGTITVEKQMVKN
                     DGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYGKLYIDSNAVCTKEDG
                     ELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKMKEISERLGHSRISIT
                     MDTYSHVTDKMRNETVDIMENLRKNS"
BASE COUNT          401 a          192 c          213 g          297 t
ORIGIN      
        1 atatcaatga tgatggctca agaaaaaaag tggagaaagt tggcggagac acccgaccag
       61 aggccgaagc tgctttacga aaagttttat cagatattga cgaaacagga caatactttt
      121 taggtacgga tactcgagta aaacaatacc ttgatttttg gatggaggaa tacgttaaac
      181 taaatctaaa atacaatacc tatgaaaact accgatttac catcaaaaat catataaacg
      241 gttatttagg aaagaaaaaa cttacggatc tctcccctgc tcttttacaa aatttcatca
      301 atgctgaatt taaaaagggt tactcgaaga aaacaatgac tattactcac tctgtcctta
      361 agaatgcgct gaatatggcg gtttatcctt ggggattaat caagcaaaat cctatgctgt
      421 atgtaaaaat accaaaatat gaagcacgac caacgactaa aaaagatcta aaaatcattt
      481 ctcttgagga ctttgatcat atgctagaaa ttactcctga aggacatcct ttctatattc
      541 ctttgaatat tggattttat acgggaatgc gcgttggcga agtttgtggt ctgacgtggg
      601 atgatgtcga tttttcaaat ggaacaatta ctgtagagaa acaaatggta aagaatgacg
      661 gcgcatgggt atatggtacg ccaaagacaa gcagttccaa tcgaacgatt tttattggac
      721 aaaccttgct agcaattctg aaaaaacata agaaacaaca attagaaaat cgaatgaagt
      781 atggaaagct ctacattgat tcaaatgcag tatgtacgaa ggaagacggt gagctagtta
      841 cgccaagtgt agtgaaatgg aatactagga ggatatcgaa tgcactctcc ctctctttta
      901 acttccattc tctcagacat actcatgcta cacttcttct cgaaaatggc gcaaaaatga
      961 aagaaatctc tgaacgattg ggccacagca gaatttcaat tacgatggat acttactcgc
     1021 atgtaacaga taagatgaga aatgaaacgg tcgatatcat ggaaaatctt agaaagaatt
     1081 cttgattttt gccaccgaaa aaa
//
LOCUS       DACGEU010000204         1092 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.211, whole genome shotgun sequence.
ACCESSION   DACGEU010000204 DACGEU010000000
VERSION     DACGEU010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1092)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1092)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1092
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.211"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(247..951)
                     /locus_tag="IXR40_002901"
     CDS             complement(247..951)
                     /locus_tag="IXR40_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362675.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
BASE COUNT          315 a          190 c          198 g          389 t
ORIGIN      
        1 tatgtttatt attagaattt tttatagtta aggttaggca tcttaagaaa tcaggcaact
       61 ccaagatatc ttcaggtaga agagaagtcg cctaacattg taggatcata ggtgatttgt
      121 tggacaggtc aagctgatat ttgagcctga tgttagaagg aatttctttt tacttgctgt
      181 agaaattatt atatgactaa aaaggctggg attttaaatc ccagcctttt atgacaaata
      241 gaatttttat cgatcagtaa tcgctgtcgc tgcaaattgt tcgatcaaag gaatcaaagt
      301 caatttgact ttgtatttcc gttcgagtgc tttttcgata acgaactcat tttcagtagt
      361 catagaaata gttgctaatt tacgaggttc atcagcattt ttttcattaa taactacttc
      421 atgttcattt tgttctgtgt aaaatttagg atactcagca acggcttttg aaaaatcagc
      481 aaaacttaaa gcggcattcg tatcagttga gcgtgtattt tcagttgtgt ccgcttttgg
      541 tttttccgtt ttttcttctg gcacactgac tgtttcttct gtaactggtg tcgcaacagc
      601 ttgcgcagtt ggttcatcgt ttttcaatcg ttgatcattc cagtaagaca cgatttcaat
      661 aagaagattg tcacggaatc gttcgaaaat cccgttttct cctgaacgaa ttctctttaa
      721 tacagtattg aagttgtcat cgattggcac gttgatccgt gtatcttcat ttgttttccc
      781 agctaatccg atcgttaaga tttgacggtt tttgggatca agcatgactt gtaacggcaa
      841 accataacgt cgcaagctct cttcttctag agaacggaat aattgtcctc ttacaccatc
      901 caatgaagga cggaattgat ttaataattt ttgtttctgt tttttcttca tatgttctct
      961 ccttcgctca taccctttcg attataagaa aaaaacagcc aaatgaaaag gagtaatgca
     1021 aaaaaacttg cgtatacgca aattacaaca gaaaaatttg cgtattttcc cgttttttga
     1081 aagaaaaata aa
//
LOCUS       DACGEU010000205         1064 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.212, whole genome shotgun sequence.
ACCESSION   DACGEU010000205 DACGEU010000000
VERSION     DACGEU010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1064)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1064)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1064
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.212"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(762..835)
                     /locus_tag="IXR40_002902"
     tRNA            complement(762..835)
                     /locus_tag="IXR40_002902"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(799..801),aa:Ile,seq:cat)
BASE COUNT          341 a          180 c          190 g          353 t
ORIGIN      
        1 ctgcgcgagg cttaccagcg agatagagat cgacgatttg ttgtttgaat tcttttgaat
       61 aggttcttcg ttgacgtctt gacatgaaaa atcctccagt gtgtttttta ttattctaca
      121 caccttattt tttctgtcta gtctagtgta gccgattcat gactgacgtg ccggacgcac
      181 gtagcgatca tcggcgttat gactatataa agtatacttt cgttgatcca gaaaggtata
      241 aagattaaag taggctacct aaaaaggtag cccggaacga attttatcac catacttgtg
      301 aaaggagata ttttttaagt tagtattaag attgtgtaat atgatgatat ctatatttta
      361 tagtatcagt gctataaaat caaaaataag tcactaatta actaccactc caattgtaag
      421 ccttttttct cacttttttt caaaaatatg gtatgctttt taatggcttc aaatataaaa
      481 gagtttaaag cgtaacacac ttatggggaa gtggtttggg gtgcgcttta aactcttctt
      541 tattattatc tcacaattta acccaaatgt ctttctattt aaaaatcaaa gtaaaacttt
      601 tcaaatatac agaagtataa ctatgtgaaa catcctttca ttaatccata aaaggataca
      661 taaaaaagcc actcatttga gtggcaatga agaaaagctt tagcttgtat aatactcttc
      721 aaaaaaattc taacacagaa cgattcaaat ggctacgtta atgtaccctg taggactcga
      781 acctacgacc ggacggttat gagccgtctg ctctgaccaa ctgagctaag ggtactggtt
      841 gttgccacat aaagccataa acaatcaacc agtagaatgt gtggcaacaa acctgttatc
      901 gcatagcttg gagtgtgact atttatgggt gatagtgaag atatgcgata acatcactat
      961 tttatcgaat aatttttata gttgtcaata tagttatgta ctgctcctca acgaggagct
     1021 atttttatcg tttaggaata tttaaatacc aacgtttgtc atgg
//
LOCUS       DACGEU010000206         1059 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.213, whole genome shotgun sequence.
ACCESSION   DACGEU010000206 DACGEU010000000
VERSION     DACGEU010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1059)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1059)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1059
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.213"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(37..993)
                     /locus_tag="IXR40_002903"
     CDS             complement(37..993)
                     /locus_tag="IXR40_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362676.1"
                     /translation="MELYTLPIIIKTEKMLKDLKQYYPLSAYEKKKLFHFLAINLLAE
                     QADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFINKTLSWLYLHDKLDQKYLRKNED
                     ETIEWLNERFIESFENQFNLLREETSQLIRRELTKIHFKLLHYTINKADEFPLDVSFF
                     RENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFSYLLLLINHIPIQLISEPVKIIID
                     FSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPDVIITNRNNLYEESASQVVVWLDP
                     PRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPEEIIDRIE"
BASE COUNT          344 a          176 c          160 g          379 t
ORIGIN      
        1 ttagaaaaag cagtcggact ttctaaaaga agttcactat tcgatcctgt cgatgatttc
       61 ttcaggaaaa tcgtctattt gcttgtcaat tttgctgtct ttgtatttct cttcttggat
      121 agtcaacaaa atctttgtaa gattccccca gtctactgct cttggcggat cgagccaaac
      181 cactacttga gatgcacttt cttcatatag attattccta ttcgtgatta taacatccgg
      241 gaactcaggc tttcctgcct ctatcacttc cgtgttcaga ttaatgtaca agcttaaatt
      301 tttcttgata aattgattat aggcagcacc ataagaaaaa tcgatgatga tctttactgg
      361 ttcagaaatc agttgaatgg gtatgtgatt gatcaataat aataaataac tgaaaaaaag
      421 aaaaaattta tcttgaagca actctttgcg ttttgacgtt agatcattta tatactctat
      481 caaatagcaa taaaatgctg gatagttttc tctaaaaaaa gaaacatcaa gtggaaattc
      541 atcagcttta ttaatagtgt aatgcaaaag tttaaaatgt attttggtta actctcttcg
      601 gatcaattgg ctcgtctctt ctcgcaacag attaaactga ttttcaaaac tttcaatgaa
      661 tcgttcattc aaccattcga ttgtttcatc ttcatttttt ctcaagtatt tttgatccaa
      721 tttatcatga agataaagcc aagagagtgt cttattgata aaaataacgg atttttctcc
      781 taatactcct tttaagtggt aaaatcctat atccgaaaaa aatagcgact gattgctagc
      841 aatatctaaa gaatcagctt gttcagccaa caggttgatt gctaaaaagt ggaataattt
      901 ctttttttca taagcagaca gaggataata ctgttttaaa tcttttaaca ttttttctgt
      961 ttttataatt ataggtagcg tatacaattc cacaaaactt atctctgttg agttaaaaag
     1021 attatataaa aaaagccgaa tgtttttagg attccctgt
//
LOCUS       DACGEU010000207         1045 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.214, whole genome shotgun sequence.
ACCESSION   DACGEU010000207 DACGEU010000000
VERSION     DACGEU010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1045)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1045)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1045
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.214"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            6..980
                     /locus_tag="IXR40_002904"
     CDS             6..980
                     /locus_tag="IXR40_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase family protein"
                     /protein_id="HAQ4362677.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTVTPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGEAKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
BASE COUNT          376 a          132 c          182 g          355 t
ORIGIN      
        1 aaactatgtg tacgtctatt acttatgtaa caagtgatca ttattttgga aggaattttg
       61 attatgaaat atcttacaat gaagtagtta ctgttactcc aagaaattat aagttgaatt
      121 ttcgaaaggt aaatgatttg gatactcatt atgcaatgat tggtattgcc gctggtatag
      181 ctgactaccc tctttattac gatgcgacaa atgaaaaagg attgagtatg gctgggctaa
      241 atttttctgg gtatgctgat tataaagaaa tacaagaagg gaaagacaat gtatctcctt
      301 ttgaatttat tccttggatt ttaggacaat gctcaacagt aggagaagct aaaaaattgt
      361 taaaaaatat caatttagca aatataaatt atagtgacga acttccttta tcccctttac
      421 attggctatt agctgataaa gaaaaatcaa ttgtcattga aagtatgaaa gatggacttc
      481 atatatatga taaccctgtg ggcgttctta ccaataatcc ttcatttgac tatcaattat
      541 ttaatttaaa caattatcgt gtcttatcga gtgaaactcc taaaaataat ttttcaaatc
      601 aaataagttt gaatgcctat agccgcggta tgggagggat aggcttgcct ggagatttat
      661 cctcagtatc tcgttttgtt aaagcgactt ttacgaagct gaattctgta tctggagatt
      721 cagagtcaga aagtattagt caatttttcc atatcttagg ttcagtagaa caacaaaaag
      781 gtttgtgtga tgtaggtgat ggaaaatatg aatatacaat ttattcttct tgttgcaatg
      841 ttgacaaagg aatctattat tatcgaacat atgaagacag tcaaattact gcaattgata
      901 tgaataaaga agacttagat agtcataagt taattagtta tccaattata gaaaaacaac
      961 aaattaaata tataaattag ttaatgtgtt gtgattgatt atttaatata gatataatac
     1021 aaaaaggcaa agatattttc aaaac
//
LOCUS       DACGEU010000208         1035 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.215, whole genome shotgun sequence.
ACCESSION   DACGEU010000208 DACGEU010000000
VERSION     DACGEU010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1035
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.215"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..>1035)
                     /locus_tag="IXR40_002905"
     rRNA            complement(<1..>1035)
                     /locus_tag="IXR40_002905"
                     /product="16S ribosomal RNA"
BASE COUNT          218 a          324 c          234 g          259 t
ORIGIN      
        1 agcacgtgtg tagcccaggt cataaggggc atgatgattt gacgtcatcc ccaccttcct
       61 ccggtttgtc accggcagtc ttgctagagt gcccaactga atgatggcaa ctaacaataa
      121 gggttgcgct cgttgcggga cttaacccaa catctcacga cacgagctga cgacaaccat
      181 gcaccacctg tcactttgcc cccgaagggg aagctctatc tctagagtgg tcaaaggatg
      241 tcaagacctg gtaaggttct tcgcgttgct tcgaattaaa ccacatgctc caccgcttgt
      301 gcgggccccc gtcaattcct ttgagtttca accttgcggt cgtactcccc aggcggagtg
      361 cttaatgcgt tagctgcagc actgaagggc ggaaaccctc caacacttag cactcatcgt
      421 ttacggcgtg gactaccagg gtatctaatc ctgtttgctc cccacgcttt cgagcctcag
      481 cgtcagttac agaccagaga gccgccttcg ccactggtgt tcctccatat atctacgcat
      541 ttcaccgcta cacatggaat tccactctcc tcttctgcac tcaagtctcc cagtttccaa
      601 tgaccctccc cggttgagcc gggggctttc acatcagact taagaaaccg cctgcgctcg
      661 ctttacgccc aataaatccg gacaacgctt gccacctacg tattaccgcg gctgctggca
      721 cgtagttagc cgtggctttc tggttagata ccgtcaaggg atgaacagtt actctcatcc
      781 ttgttcttct ctaacaacag agttttacga tccgaaaacc ttcttcactc acgcggcgtt
      841 gctcggtcag actttcgtcc attgccgaag attccctact gctgcctccc gtaggagttt
      901 gggccgtgtc tcagtcccaa tgtggccgat caccctctca ggtcggctat gcatcgtggc
      961 cttggtgagc cgttacctca ccaactagct aatgcaccgc gggtccatcc atcagcgaca
     1021 cccgaaagcg ccttt
//
LOCUS       DACGEU010000209         1030 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.216, whole genome shotgun sequence.
ACCESSION   DACGEU010000209 DACGEU010000000
VERSION     DACGEU010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1030)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1030)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1030
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.216"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            <1..650
                     /locus_tag="IXR40_002906"
     CDS             <1..650
                     /locus_tag="IXR40_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362678.1"
                     /translation="VFKILNKNSIFKKKIDDYFVYCPELLLYDVKNIKKIPKIDENSK
                     LMKNIQSIFGIEEVFVGDKCIFFDQPLLSDGYGIDETDIFAKVNSIFSGKKETLIKLH
                     PRARTNRYGEKNILNSSLPFEVLLLENDFSSTLLISPISTISFSPSMMFEKTINSIML
                     AKLILNEYTALSEDKKETLTNIVLFCEHYNRLSEEKILLPENWAELRKLVEYGII"
     gene            637..>1030
                     /locus_tag="IXR40_002907"
     CDS             637..>1030
                     /locus_tag="IXR40_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HAQ4362679.1"
                     /translation="MGLFNTLSKSKLVKSSFWYTIGNFFIKGISFITIPIFVNITTQA
                     EYGLINNFTSFVSIFSILVGLSLNSAINNASFDYKDDINEFMSSVLSLATLSLIVFLL
                     IGNIYFLFSNAFFDMNQLVFNLMLLQSFA"
BASE COUNT          366 a          132 c          148 g          384 t
ORIGIN      
        1 gagtttttaa aatattaaat aaaaatagca tcttcaaaaa aaaaattgac gattattttg
       61 tctattgtcc ggaattgtta ctttatgatg taaaaaatat aaaaaaaatt cccaaaatag
      121 atgaaaacag taaattgatg aaaaacatac aatcaatctt tgggatagaa gaagtttttg
      181 tcggagataa atgtatcttt tttgatcaac ctttattatc tgatggttat ggcatagatg
      241 aaacagatat tttcgctaaa gtaaatagta tattttctgg aaaaaaagaa actttaatta
      301 agcttcatcc tagagcaagg acaaatcgtt atggtgaaaa aaacatattg aattccagtt
      361 taccgtttga agtcttgcta cttgaaaatg acttctcttc aacacttttg attagtccta
      421 tatctacaat ttctttttca ccatctatga tgtttgaaaa gacgatcaac tctattatgt
      481 tggctaaatt aattttaaat gaatatacag cattatctga agataaaaaa gaaacattga
      541 caaatattgt tcttttctgt gaacattata accgtctatc agaagaaaaa attttactcc
      601 cagaaaactg ggcagaatta agaaagttgg tagagtatgg gattatttaa cacactttcc
      661 aagtcaaaat tagttaagtc cagtttctgg tatactatag ggaatttttt tattaaggga
      721 atttcattca taactattcc tatttttgta aatattacta ctcaagcaga atatggtttg
      781 attaataatt tcacttcatt tgtatcaatt ttttcgattc ttgttgggct aagcctaaat
      841 tcggcaatta ataatgcaag ttttgactat aaagatgaca taaatgaatt tatgtcatcg
      901 gtactttctc tagctacact ttcgttaatt gtgttcttat taatagggaa catatatttt
      961 ttgttttcaa atgctttttt tgatatgaac caacttgtat ttaatttgat gttattacaa
     1021 agttttgcta
//
LOCUS       DACGEU010000210         1024 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.217, whole genome shotgun sequence.
ACCESSION   DACGEU010000210 DACGEU010000000
VERSION     DACGEU010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1024)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1024)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1024
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.217"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            281..973
                     /locus_tag="IXR40_002908"
     CDS             281..973
                     /locus_tag="IXR40_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HAQ4362680.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSLKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
BASE COUNT          441 a          145 c          170 g          268 t
ORIGIN      
        1 cgttttttgt aataaataca gtaatctatg aaatgaaaag ggttacgttt aataaaactt
       61 gcttttttgt ttttgttcac cataaatatt tatttaagaa agtattaacc tgcatttttc
      121 tctataaaaa agatttttta aatagataaa aaaggaggat taaatgagta tttgatagta
      181 tttatattaa aattacatat gtaatttaaa aacgcttgac attgtgtttg agatcactta
      241 cttttagcat gtaaaagtat tggattaagg agctatgcaa atgaaaaaga aatttattac
      301 tggtgggatt gtcgttgcat ttctatgtct aattggctac acaggcacgc ggtacgcaaa
      361 tgaaattatt ttgtggggtg gagagacaga tattgataca atcaatgaga atctgacaca
      421 gcttgatcat acattgacag ataaagagca agcgattaca gatcttaccg ctcgactagc
      481 acaaaaagaa cagacattgc aagattcaaa ggcagatgtc caagaatacc aaacaaaagt
      541 aaatgaatta gaaaaccaaa aaaatcaatc ggcagcagaa aaacaaaact tagaaagtca
      601 attagtcagc aaggatgcac aactacaaag caaacaaaat gaaatcaatg tcaaactaga
      661 tgagatcaac caaaaaaatg atgaaatcaa tcatctgaat gcagattgga cagcaagact
      721 acaagaagca caagcaaaac tttcagaatt acaaaatact gtaaatggtt tgaatcaaca
      781 aatcgcaaca ctgacacaag aaaaaacaaa tgtagaaact cagttaacag atacacaaaa
      841 gaaattagac gaagcaactg ctgaaaactc aagcttgaaa caatatattc aaaagttaga
      901 aaaagcaaaa gatgaagtgg aagatacagc tgataaatct cagcaaattg ttgaagaaca
      961 tttgcgtaaa taatctttct taacaagtaa acctaaatta gtaaagaagc aacagtaatc
     1021 tata
//
LOCUS       DACGEU010000211         1014 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.218, whole genome shotgun sequence.
ACCESSION   DACGEU010000211 DACGEU010000000
VERSION     DACGEU010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1014)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1014)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1014
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.218"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            <1..>1014
                     /locus_tag="IXR40_002909"
     rRNA            <1..>1014
                     /locus_tag="IXR40_002909"
                     /product="23S ribosomal RNA"
BASE COUNT          272 a          229 c          310 g          203 t
ORIGIN      
        1 caagctgtga tggggaggga aataatagta ccgaagttcc tgatgtcaca ctgccgagaa
       61 aagcttctag tgagaaaaca gcggcccgta ccgcaaaccg acacaggtag tcgaggagag
      121 aatcctaagg tgagcgagag aactctcgtt aaggaactcg gcaaaatgac cccgtaactt
      181 cgggagaagg ggtgctgatc atacgatcag ccgcagtgaa taggcccaag cgactgttta
      241 tcaaaaacac aggtctctgc aaaatcgtaa gatgaagtat aggggctgac gcctgcccgg
      301 tgctggaagg ttaagaggag tgcttagcgc aagcgaaggt acgaattgaa gccccagtaa
      361 acggcggccg taactataac ggtcctaagg tagcgaaatt ccttgtcggg taagttccga
      421 cccgcacgaa aggcgtaacg atttgggcac tgtctcaacg agagactcgg tgaaatttta
      481 gtacctgtga agatgcaggt tacccgcgac aggacggaaa gaccccatgg agctttactg
      541 tagtttgata ttgagtgtct gtaccgcatg tacaggatag gtaggagccg tagaaatcgg
      601 aacgctagtt tcgatggagg cgctggtggg atactacccc tgcgttatgg ccactctaac
      661 ccgcaccact aatcgtggtg ggagacagtg tcagatgggc agtttgactg gggcggtcgc
      721 ctcctaaaag gtaacggagg cgcccaaagg ttccctcaga atggttggaa atcattcgaa
      781 gagtgtaaag gcagaaggga gcttgactgc gagaccaaca agtcgagcag ggacgaaagt
      841 cgggcttagt gatccggtgg ttccgcatgg aagggccatc gctcaacgga taaaagctac
      901 cctggggata acaggcttat ctcccccaag agtccacatc gacggggagg tttggcacct
      961 cgatgtcggc tcgtcgcatc ctggggctgt agtcggtccc aagggttggg ctgt
//
LOCUS       DACGEU010000212         1003 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.219, whole genome shotgun sequence.
ACCESSION   DACGEU010000212 DACGEU010000000
VERSION     DACGEU010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1003)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1003)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1003
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.219"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            <1..>1003
                     /locus_tag="IXR40_002910"
     CDS             <1..>1003
                     /locus_tag="IXR40_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAQ4362681.1"
                     /translation="KKISMILLNRSGNKRTYLRLKKQRYLCRACKKYFTARTYLVTPF
                     CFISKQIHYKILEELTERQSIKAIGKHCDVSVTTVQRTLSALSSDIRQNLEYLPRCLL
                     FDEFRSLSTWHGKFSFSCMDGETGKLFEILPSRRKKDLVAFFMRFSLKARLGVHYIVT
                     DMNAPYFSLVKECFPNAQVIVDRFHIVQHLNRFFDAVRKRVMKTLDQKDPIQAKQYRQ
                     LKSLFKLLLKSEDRLDYNTLTKRRNFNWRLLTETEVVDRLLKISPELKTAYRYYQDLL
                     TAYQEKDPDTFFQLLRAMPGEVPLELHHIKKAFFKYEKGIRLALLKKYSNARLENLHT
                     "
BASE COUNT          301 a          210 c          190 g          302 t
ORIGIN      
        1 gcaagaagat ctctatgatt ctcctgaatc gtagcggtaa taaacggacc tatcttcggt
       61 tgaagaaaca gcgatacctc tgccgagcat gtaaaaaata ttttaccgct cggacgtatc
      121 tcgttacccc attctgcttt atttctaagc agattcatta caagatctta gaagaattga
      181 cagagcgtca atctataaaa gcaattggta aacattgcga tgtttctgtg acaactgttc
      241 agcggacatt gtccgccttg tcatcagata tccgtcagaa tcttgagtat ttacctcggt
      301 gtctattatt cgatgagttt cgttctcttt ctacatggca cggtaaattt tctttttctt
      361 gtatggacgg tgagaccggg aaactgtttg agatcttacc tagccgccgt aaaaaagatc
      421 tcgttgcttt tttcatgcgt ttttctctca aagcgaggtt gggtgtacat tacatcgtaa
      481 cggatatgaa cgctccttat ttctcactag ttaaagagtg ttttccaaat gcacaagtga
      541 tcgtcgatcg gtttcacatt gttcaacatc tgaaccgctt cttcgatgcg gttcgaaaac
      601 gtgtgatgaa aacacttgat caaaaagacc caatacaagc taaacagtat cgccaattga
      661 aatccttatt caaattactt ttaaaatcag aggatcgttt agattacaat acactaacga
      721 aaagacgcaa tttcaattgg agactattga ctgaaacaga agtagttgac cgccttctaa
      781 agatttctcc tgaacttaaa acagcttatc gttactacca agacctgctt actgcgtatc
      841 aggaaaaaga tccagatact tttttccagc tgcttcgagc aatgcctgga gaagttccat
      901 tggaactgca ccatatcaaa aaagcctttt tcaaatacga gaaagggatt cggctggcat
      961 tactgaagaa gtattcgaat gcacgactgg aaaatctcca tac
//
LOCUS       DACGEU010000213         1000 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.220, whole genome shotgun sequence.
ACCESSION   DACGEU010000213 DACGEU010000000
VERSION     DACGEU010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1000)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1000)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1000
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.220"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            369..1000
                     /locus_tag="IXR40_002911"
                     /pseudo
     CDS             369..1000
                     /locus_tag="IXR40_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          342 a          181 c          183 g          294 t
ORIGIN      
        1 tttcaaagtt agtagagaaa atgtagttat atatttaaat ttttaccaga aagaaatgaa
       61 caccttcaat tatctaaatc tcgaaaatgg ttagatgtaa tcatcaggaa aaacaatctt
      121 aaacgaatta ctattcatgg tcttagacac acacatgcta gcttgctttt agcaagctag
      181 tgcaaatatt aaagatgtgc aagagcgttt aggccactct tctattcaaa tcattatgga
      241 tctatatatt catattacag acaaaagaaa agaagaaacc gtagcgcaat tcgcaaaata
      301 taggctctat aatttatggg actgatgaat caaaattgat tcttcagtcc cattgttatt
      361 ttaggtatat gattcgtaca ttgaaagagt tgaaaaacta tcttccgaag ccgtcaaaaa
      421 ggaccctgcc aaaagtattg atggtggatg aatttcgttc gcacgcttca attgtggata
      481 aaatgagctt tatttgtgcg gatggcgaga ctggaaaact cattgatatt ttgcctacac
      541 gaaaattgtc tcgattaaca cactatttta gtcgctgtgc aaatcctgaa gcggtggaat
      601 atttagtgac agatatgaac gccgcctact tccaactgac aaaacgtgtc ttaccaaatg
      661 cgaaagtcgt cattgattgt tttcatatca tcaaacattt gaatcaggcg ttcaatgatt
      721 ttcgtgtaca agaaatgaaa agattacacc agttagggca acgacgggaa gccgagaaag
      781 tgaaaaagaa ctggcgcttt cttctaaaaa accgtcaaaa aatcaatcac tatgattaca
      841 aaacatggcg cagttttcgt gcacctaaat acccgctact cactgaagca atgatgattg
      901 atcgattgct ggcattttca acgcctttaa aggacgccta tacttttttc catgagctga
      961 ccgaagcctt tagagacaag gaatcagact tattttttac
//
LOCUS       DACGEU010000214          998 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.221, whole genome shotgun sequence.
ACCESSION   DACGEU010000214 DACGEU010000000
VERSION     DACGEU010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 998)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 998)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..998
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.221"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(80..634)
                     /locus_tag="IXR40_002912"
     CDS             complement(80..634)
                     /locus_tag="IXR40_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAQ4362682.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADVAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGG"
BASE COUNT          323 a          185 c          107 g          383 t
ORIGIN      
        1 ttccgaaaat tcagttatct tcattaatct caccttctaa gttttcatta tacacaaaaa
       61 atatatccta atatctcaat tagcctccca atttaaaacc acgtaacgat gcccctattt
      121 catcttcagt tataccaatg tacctttttg taattgcttg cgagctatga ttaaaaataa
      181 acattaaggt agcaatgtct ctagttttct tgtagtagtg atacccaaaa gtttttctta
      241 atgtatgtgt tcctatatca tctcttccta atttttctgc tacatctgca tatatctgat
      301 agacacgatc ccttgttata tgtcgacctt gttgccgact tggaaataac caatcatttt
      361 cttctttacc ttcagtatat aataaaatct cttctctcaa attatctata aaaatcggtt
      421 ttcgcttacc tgttttatgt tcaacaataa taggcttact tttacctcgt atgtctccaa
      481 cttttaatcc tataatatct gacatacgta acccattatt gattccaaac aaaaataaaa
      541 aactatctct ttctggatta cttgttcttc ttagccaaaa ctgaaaatct tgtatctctt
      601 catttgtcct taacggttgt acattatagc tcactattgt ttcccttctt aaaaatattc
      661 tgagttcatg attatatata tattttacca taatcatgaa cttatatata tactctgtta
      721 aaagtgaaga aaatcaaggg gtttagttta tgattttata tcatttcagt aactcagaat
      781 attccgactt ttttgtacaa aaaaattaac cttacttata tgaagattct aagctcttat
      841 ttaaatttta gacgggcagt tatccgtaga agttcttaga atagctaatt tacataatta
      901 aattatatga aatttaagtt tgaacaatat actaagaact ccccttacta taaagtgaaa
      961 taaattagca tatgaataac cgtgctacca aacttttc
//
LOCUS       DACGEU010000215          978 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.222, whole genome shotgun sequence.
ACCESSION   DACGEU010000215 DACGEU010000000
VERSION     DACGEU010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 978)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 978)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..978
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.222"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            82..>978
                     /locus_tag="IXR40_002913"
     CDS             82..>978
                     /locus_tag="IXR40_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HAQ4362683.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYE"
BASE COUNT          333 a          182 c          192 g          271 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcaccac aaaataaaca
       61 actgagagga cgatacgcta tatgaatgat tctatcaaaa aaatgctgag aataacagag
      121 aaagatttga tgattacaga ggtctcttac gagacccttc agaagaaaaa gacgttggtc
      181 gtcgatgctg ttctctcgcc tactcctcgt gcttgtagaa gttgtggttc tactgtggta
      241 gatggaaacg ggaaagcaat tatagtgaaa aatggaaaaa aggaaacgat tgtccgtttt
      301 gaacaataca atcatatgcc tttggttatg cgcctaaaaa agcaacgcta tacctgtaaa
      361 aactgtcgca cccattggac ggctcaaagt tattttgtcc aacccagaca ttcaatcgca
      421 aatcatgtta gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaagct gtcaggtatc tttgaccacc gttattcgta cattgaaaga gtttaaaagc
      541 tatttaccaa agcaatctaa gaagatcctc cccagagtat tgatggttga cgaatttcgt
      601 tcgcatgctt ccatagaaga taagatgagc tttatttgcg cggatggcga aacaggaaaa
      661 ttaatagatg ttttgcctac gcgtaaatta cctcgattaa caagctattt cttaggttgt
      721 accaatccag aagaagtaga attcttggtg acagacatga acgccgccta cttccagctc
      781 accaaacgtg ttctgccaaa tgcgaaagtc gtgattgatc ggtttcatat tgtcaaacac
      841 atgaatcaag cgttcaatga gttgcgtatc cgtgaaatga atgaacttcg taaagccgga
      901 cagaaaagcc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaa
//
LOCUS       DACGEU010000216          951 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.223, whole genome shotgun sequence.
ACCESSION   DACGEU010000216 DACGEU010000000
VERSION     DACGEU010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 951)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 951)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..951
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.223"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..251)
                     /locus_tag="IXR40_002914"
     CDS             complement(<1..251)
                     /locus_tag="IXR40_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAQ4362684.1"
                     /translation="MKKLKIFPKMFIQIFSVLGIIIILVHSLIFFIFPKTYLETRKEK
                     IHNMANEISSNMNGKEIKYIEQTLEFYSKSSEIKVFIKE"
     gene            complement(248..901)
                     /locus_tag="IXR40_002915"
     CDS             complement(248..901)
                     /locus_tag="IXR40_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAQ4362685.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
BASE COUNT          305 a          163 c           80 g          403 t
ORIGIN      
        1 ttttctttta tgaatacttt tatttcacta ctcttggaat aaaactccaa agtttgttct
       61 atatatttta tttcttttcc attcatatta ctagaaattt catttgccat attatgaatc
      121 ttttcttttc tcgtctccaa atatgtttta ggaaagataa aaaaaattaa tgaatgaact
      181 aatataatta ttattccaag aacagaaaat atttgtatga acatttttgg aaatatcttt
      241 aattttttca ttttctctcc aatttatatc ctacatttct tatagtagtt atacagtcta
      301 attgtaattt ttttctaagt tcttttatat atacatctat tactcgatca taaggagttt
      361 cttcgctatc tttccataca taatcaataa tttgcattct tgttaacact tgtccattat
      421 tatccaataa acattttaat acttctagtt cttttgcatt tacatctatt tcttcaccat
      481 ttattttagc tgtatagcta ttaaaattaa ccgatagatc cttatattca aacttctcta
      541 aatgtccata attcttctta attaaagaat ctattctagc ttttaagacc ggcaatgaaa
      601 atggcttttc tacatatccg tctactaaat tagtaaatgc atcaatttta tattcttcat
      661 cactaaatgc agtcaagatt agaattggta aattgctttt ctttctaatt tctttcaaca
      721 cttctaaacc atttataaaa ggtatctgaa tgtctaagat aaccaaattt atatcgctat
      781 taaattttga caaggcttct cttccatctt tagcttgaat aacagtatat ccaaattctg
      841 aaagatattc acttattccc tctcttatca tattatcatc ttcaacagtt aatattttca
      901 tatatacctc cacttaagcc tatacactag atattataca gcatattatg g
//
LOCUS       DACGEU010000217          943 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.224, whole genome shotgun sequence.
ACCESSION   DACGEU010000217 DACGEU010000000
VERSION     DACGEU010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 943)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 943)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..943
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.224"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            2..>943
                     /locus_tag="IXR40_002916"
     rRNA            2..>943
                     /locus_tag="IXR40_002916"
                     /product="23S ribosomal RNA"
BASE COUNT          293 a          187 c          274 g          189 t
ORIGIN      
        1 attgtgtgaa tacatagcac attcgaggta gacgcagaga actgaaacat ctaagtacct
       61 gcaggaagag aaagaaaatt cgattccctg agtagcggcg agcgaaacgg gaaaagccca
      121 aaccagcaag cttgcttgtt ggggttgtag gactccaata tggtagttct ttcagatagt
      181 cgaatgactt ggaaaagtca gtcaaagagg gtaaaaaccc cgtagacgaa atgtggaaga
      241 cacctaggag gatcctgagt acggcggaac acgagaaatt ccgtcggaat ccgggaggac
      301 catctcccaa ggctaaatac tccctagtga ccgatagtga accagtaccg tgagggaaag
      361 gtgaaaagca ccccggaagg ggagtgaaat agaacctgaa accgtgtgcc tacaacaagt
      421 caaagcccgt taatgggtga tggcgtgcct tttgtagaat gaaccggcga gttacgattg
      481 catgcgaggt taagttgaag agacggagcc gcagcgaaag cgagtctgaa tagggcgttt
      541 gagtatgtag tcgtagaccc gaaaccatgt gatctaccca tgtccaggtt gaaggtgcgg
      601 taaaacgcac tggaggaccg aacccacgta cgttgaaaag tgcggggatg aggtgtgggt
      661 agcggagaaa ttccaaacga acttggagat agctggttct ctccgaaata gctttagggc
      721 tagcctcgga attgagaatg atggaggtag agcactgttt ggactagggg cccatctcgg
      781 gttaccgaat tcagataaac tccgaatgcc attcattcat atccgggagt cagactgtga
      841 gtgataagat ccatagtcga aagggaaaca gcccagacca ccagctaagg tcccaaaata
      901 tatgttaagt ggaaaaggat gtggggttgc acagacaact agg
//
LOCUS       DACGEU010000218          873 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.226, whole genome shotgun sequence.
ACCESSION   DACGEU010000218 DACGEU010000000
VERSION     DACGEU010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 873)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 873)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..873
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.226"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(397..597)
                     /locus_tag="IXR40_002917"
     CDS             complement(397..597)
                     /locus_tag="IXR40_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAQ4362686.1"
                     /translation="MKINYTVDLVSFSLVINFSLFSLRLFIDGLRHTHASILLYQGVN
                     ILSVSKRLGHSSLETTMSTYTK"
BASE COUNT          316 a          134 c          143 g          280 t
ORIGIN      
        1 tcttattaga atagtagaga ttgattaata agctatcttc gattgctaaa aagaaaactt
       61 ctgaattcca tactttataa aaatctttga taaatctatt cgaagggtca aatttaaacc
      121 ataattgtgt ttttccttcc atcagcataa aagttcacct caaaaagagt atacgaacga
      181 atgttctttt tgtgaaggcg gaatttaata tactgaataa tagaaaacaa gtacttgtgc
      241 caaattatgt gccaaaaaaa ttcgaattca acaaaatgta aacaaataga aaaccttcta
      301 tattaagatt tcctgcaata acaaacacaa cagaagacgt gtaatagtta gtcaggaacg
      361 tacaaataac ccctgtatcc tttgcggtac agggggttat tttgtataag tagacattgt
      421 agtttctaaa ctgctatgtc ctaaacgttt cgatacgcta agtatattta ctccttgata
      481 aagtaaaata gatgcatgcg tatgtcttag tccatcaata aacagtcgaa gagaaaatag
      541 ggaaaaattg attactaaag aaaaacttac taggtcgacg gtgtagttga ttttcatact
      601 tcaatagatt cgaattaaac gatttcgatt ggcttatacc agtcctatcc aacgaaagat
      661 atatcgttct taactctagc ggtataactt gaagctttac gtaaagccaa tgggaatgaa
      721 ctggagatga ctttttatta tttttagtaa tagctgatgg gttaatactt acaactttcc
      781 ttttcaaagt accatataaa aaaacggtgg ggttgtttag cgaaataaag gatctaagcc
      841 aatagcttag atcctttatt ctatgcttta tat
//
LOCUS       DACGEU010000219          839 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.227, whole genome shotgun sequence.
ACCESSION   DACGEU010000219 DACGEU010000000
VERSION     DACGEU010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 839)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 839)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..839
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.227"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
BASE COUNT          304 a           82 c          141 g          312 t
ORIGIN      
        1 atagtaatgt ggattatcac cttccaacag tatataaaat gagcgtaaaa acggctattt
       61 ttgccttaac aacgattttt ttgtatacaa atacgatatg ctcattaatt attggaattt
      121 gtagtgctgt ttaaattaat gaaggtgtaa ttatatgagt gatcattttg aaaaagtttg
      181 ttgagaagat gtgcttctag tcatgtgatg ggagaaaata atttaactgt tagagtgaat
      241 agttaaatta ttctggttat atgaaaaaag tagtttctaa aataatcttg cagggattaa
      301 cttaaagaaa ttgagagaat agtttctttg aaatttctat atacaatgag aagctgaaat
      361 ttacttttat ttgatgactg gaaatagaaa ttaaatatat tgtattgtta cattaaagaa
      421 aacttgtatg gaaaaatcag tacaatacca ttatttaatg ttcttcactt aaagcgcaaa
      481 aaatatcagt ttattaaact cgtatataga acaaatatat gtagacgggg cgaaacgatg
      541 agtgtaaaaa aaatgctatt tatggtaagt acaataattg tattaacatc ccgattttgg
      601 ggaattaata ctagtttatc tatgcgatat tttattatgg caatatggga tttatatttt
      661 atgttaagct atttttctta tcgtgagaaa acatataaaa aatacgttat caagaataac
      721 ttttggttga ctataatgcc gtttgtgata ttttctatct atactctaat aatatgggga
      781 attggttcaa atgcagaatt tgaaaatttt ataaagttat gttccacgtt gctttattt
//
LOCUS       DACGEU010000220          800 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.228, whole genome shotgun sequence.
ACCESSION   DACGEU010000220 DACGEU010000000
VERSION     DACGEU010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 800)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 800)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..800
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.228"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            <1..159
                     /locus_tag="IXR40_002918"
     CDS             <1..159
                     /locus_tag="IXR40_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HAQ4362687.1"
                     /translation="RRNKFYRSLRTASSTIKGMETIRGIYKKNRRNGTLFGFSVSTEI
                     KVLMGIPA"
     gene            242..>800
                     /locus_tag="IXR40_002919"
     CDS             242..>800
                     /locus_tag="IXR40_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011834674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362688.1"
                     /translation="MWIFKQEIFAKLFSLDGLGWGILFFIFLFLGSMWIWFVDKKNSY
                     EKVIVKKMNRNEFDDFSKEHRVELYDSHEINSTSPSYYWVFGCEEKPLEIKLLKMLEN
                     PPVIEDFSAKNVEKQMFEQVQIRGQNKISLEPDEYAAFFLETNSGTSMPVFKVKLKMN
                     GRLCTYDLVANMRYGSTGDRRTILKF"
BASE COUNT          273 a          101 c          161 g          265 t
ORIGIN      
        1 cgacggaata aattttatcg aagtctccgg actgcctcat ccacgattaa ggggatggag
       61 accattcgag gaatatataa aaagaaccga agaaatggaa cgctcttcgg cttttcggtg
      121 tctactgaga tcaaggtatt aatgggaata ccagcctaag atatttggag ttcagagagg
      181 gcgcgtttga ttttcaaact tcgcaacaga accattattt taaagtggga ggaaaattgt
      241 tttgtggata tttaaacaag aaatctttgc taaattattt agtttagatg gattaggttg
      301 gggaatctta ttttttattt ttttattttt aggatctatg tggatctggt ttgttgataa
      361 aaaaaattct tatgagaaag taatagtgaa aaaaatgaat cgaaatgaat tcgatgattt
      421 ttcaaaggaa catagagttg aattgtacga tagtcatgaa attaacagta cttctccatc
      481 ttattattgg gtatttggtt gcgaagaaaa accattggag attaaattgt tgaaaatgct
      541 tgaaaatcct ccagtcattg aagatttttc tgcaaaaaac gttgaaaaac agatgtttga
      601 acaggtacaa ataagaggtc aaaacaaaat ttcattagaa ccagatgaat atgcagcctt
      661 ttttttagaa acaaattcag gtacttcaat gcctgttttc aaagttaaat taaaaatgaa
      721 tggtcgttta tgcacttatg atcttgttgc aaatatgcgc tatggttcta ctggtgatag
      781 acgtactatt ttaaaatttg
//
LOCUS       DACGEU010000221          787 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.229, whole genome shotgun sequence.
ACCESSION   DACGEU010000221 DACGEU010000000
VERSION     DACGEU010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 787)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 787)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..787
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.229"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(42..>787)
                     /locus_tag="IXR40_002920"
     CDS             complement(42..>787)
                     /locus_tag="IXR40_002920"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAQ4362689.1"
                     /translation="RNNKLKKKISTIFFTNKQRYGATKIHQVLLKEGISVSLKHVQKL
                     MKQLNLRSIVVKKYRPQRSNKPIISKENLLNQDFSTETICEKWAADITYIPTKKNGWC
                     YLSSIMDLHTKKIISYTFSKRMTVDCVIQTLNKAKIHYHIPEGMILHTDLGSQYTARE
                     VEQWLKTNKIRHSYSRKGTPYDNAGIESFHASLKKEEVYTTSYSDFEEANRALFSYIE
                     GFYNRNRIHSSIHYLTPQEFEELAKEKMA"
BASE COUNT          214 a          126 c          136 g          311 t
ORIGIN      
        1 ggatttgagt caatatcttg gacacatttt agtagagacg gttaagccat tttttctttt
       61 gctaattctt caaattcctg tggggttaga tagtgaatcg agctatggat tcgatttcgg
      121 ttataaaatc cttcaatgta gctaaatagc gctcgatttg cttcttcaaa atctgagtag
      181 ctagtcgtgt agacttcttc ttttttcaat gaggcatgga aagattcgat tccagcatta
      241 tcataaggtg ttccttttct actataagaa tgccttattt tgttggtttt aagccattgt
      301 tccacttctc ttgctgtgta ttggctgccc aagtcagtgt gtagaatcat tccttctgga
      361 atgtgataat gtatttttgc tttattcaat gtttgaatga cacaatccac agtcattcgt
      421 tttgaaaatg tataactaat aatttttttc gtgtgtaaat ccatgattga agataagtaa
      481 caccaaccat ttttcttagt aggaatgtac gtaatgtcag ctgcccattt ctcacagatc
      541 gtttcagtag aaaagtcctg atttaagaga ttctcttttg aaatgatcgg tttattagac
      601 ctttgaggtc tatatttttt aactacaatc gaccttaaat ttaattgttt cattagcttt
      661 tggacatgtt taagagatac tgaaatccct tcttttaata aaacttgatg gatctttgtg
      721 gcaccatagc gttgtttatt cgtaaaaaaa attgttgaaa tcttcttttt caacttatta
      781 tttctga
//
LOCUS       DACGEU010000222          783 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.230, whole genome shotgun sequence.
ACCESSION   DACGEU010000222 DACGEU010000000
VERSION     DACGEU010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 783)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 783)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..783
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.230"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            24..716
                     /locus_tag="IXR40_002921"
     CDS             24..716
                     /locus_tag="IXR40_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HAQ4362690.1"
                     /translation="MGLAFLLAGCTNGNESKKESTKETAKATVATTTTTSTESKSTAA
                     STETADTSTSSESSKTTETTQTSTSSSSVEASSSSSESSEQVEQTLWNADKSAQLEAF
                     MTKWGQTMGQQYKSYTNQMSVDLYGLKVPQAILNGEWKMAIGGVPVSAEWSESGTGQA
                     DYQITAVYSDAETEPYLKKHVYLFGFQQNQPKVLVTQQNQGNPDNYLYFNETANNELK
                     NGFNQIVYGQAN"
BASE COUNT          281 a          151 c          159 g          192 t
ORIGIN      
        1 tgaaaaaaag gattttagta acaattggtc tagctttttt gttagctggt tgtaccaacg
       61 ggaatgaatc gaaaaaagaa tcaacaaaag aaacagcgaa agcaacagtt gcaactacta
      121 caacaactag cacagagagc aagtcaactg cagcaagtac agaaacagca gatacctcta
      181 cttcgtcaga gtcttccaaa acgactgaaa caactcaaac atctacttca agttcttctg
      241 tagaggcttc atcttcctct tcagaaagca gcgaacaagt tgaacaaaca ctgtggaatg
      301 cagacaaatc cgcacaatta gaggcattta tgaccaaatg gggccaaaca atgggacaac
      361 aatacaaaag ttatacgaat caaatgagtg tggacttata tggtcttaaa gtccctcaag
      421 ctattttgaa cggggagtgg aagatggcta ttggtggagt gcctgtttct gcagaatggt
      481 cagaaagtgg gacaggtcaa gcagactatc aaatcacagc cgtctattcc gatgcagaga
      541 cagaaccata tctgaaaaag cacgtctatc tattcgggtt tcagcaaaat cagccaaaag
      601 tattggtgac acaacaaaat caggggaatc ccgataatta tctttacttc aacgagacag
      661 cgaataatga attgaaaaat ggctttaatc aaatcgttta tggacaagca aattaatgag
      721 ataaacaagg ggttgtgaca tgtcttttat cacaacccct tgctcagttt atttgttagt
      781 ctt
//
LOCUS       DACGEU010000223          768 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.231, whole genome shotgun sequence.
ACCESSION   DACGEU010000223 DACGEU010000000
VERSION     DACGEU010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 768)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 768)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..768
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.231"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            120..>768
                     /locus_tag="IXR40_002922"
     CDS             120..>768
                     /locus_tag="IXR40_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAQ4362691.1"
                     /translation="MTIKTSLQNQAYQSIRRQIIYADLEPGKKVSEKKLEETLSIGRT
                     PIREALIQLRQQGLVDTIPQSGNYISLIDLDSAKNARFVREHLERQIMLECCAKMNNQ
                     KKRILETIISEQEKAVSQKNARSFFHNDNLFHKACFEIAEREEVWQWLENNNTHLERF
                     RWLRVKTEGLKWEKIMEQHYQLFEALTKQDPEEANFLTSLHLHLMLNEQNIVLATH"
BASE COUNT          298 a          114 c          121 g          235 t
ORIGIN      
        1 tttctttttt tcatgtattc ttttattttt ataactagtg tattacttca aaatttgata
       61 ttatatggca tgaacagaat taaaatatca gttaaaataa aagttaagga gcattgtgta
      121 tgacaattaa aactagtctc caaaatcaag cttaccaatc tattcgccga caaattatct
      181 atgctgactt agaacctgga aaaaaagtat cagaaaaaaa attagaagaa acactttcta
      241 ttggtcgtac accaatacgt gaagcactga ttcaactccg acaacaaggt cttgttgata
      301 caattcctca aagcggaaat tatatctcat taattgattt agattcggcc aaaaatgctc
      361 gatttgtcag agaacatttg gaacgacaaa ttatgttaga gtgttgtgcc aaaatgaata
      421 accaaaaaaa acggatttta gaaactataa tttcagaaca agaaaaagct gttagtcaaa
      481 aaaatgctcg tagttttttt cataatgata atttattcca taaagcttgt tttgaaattg
      541 cagagcgaga agaagtatgg caatggttag aaaataacaa tacacactta gaacgatttc
      601 gatggctacg agtaaaaacg gaaggattaa agtgggaaaa aattatggaa caacattatc
      661 aactatttga ggcattaaca aaacaagatc cagaagaagc taactttcta acatcgttgc
      721 atcttcattt aatgcttaat gagcaaaata ttgttttagc tactcatc
//
LOCUS       DACGEU010000224          739 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.232, whole genome shotgun sequence.
ACCESSION   DACGEU010000224 DACGEU010000000
VERSION     DACGEU010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 739)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 739)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..739
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.232"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            39..686
                     /gene="eda"
                     /locus_tag="IXR40_002923"
     CDS             39..686
                     /gene="eda"
                     /locus_tag="IXR40_002923"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HAQ4362692.1"
                     /translation="MKKVEILSKLEAAGVIAVVRGKNKDEAIKAINSIIAGGIKGIEL
                     TFTVPNAEEIIKEIAKKYADQKDVIIGAGTVLDAFTARIAIMAGAEYIVSPSFDRQTA
                     EICNLYQIPYLPGCMTITEIKEALTAGVDIIKLFPGSAFGPSIVKAYQAPLPHVNIMP
                     TGGVSIENLEDWFEVGVVAVGVGGNLLASVEKGDFEEVSRVASKYIDKFYEIKNY"
BASE COUNT          263 a           94 c          162 g          220 t
ORIGIN      
        1 ctagacaaag tatgtatcca taaaggaagg agatagatat gaaaaaagta gaaattttaa
       61 gtaagttaga agcggctgga gtcattgcgg ttgtacgtgg gaaaaataag gatgaggcca
      121 ttaaagcaat aaattcaatt attgcgggtg gaattaaagg gattgaacta acttttacag
      181 ttcctaatgc tgaagaaata atcaaagaaa ttgctaaaaa atatgctgat caaaaagatg
      241 taataatcgg agccggtacg gttttagatg cgtttactgc tcgtatcgca attatggctg
      301 gggcagaata tatcgttagt ccatcttttg atcgacaaac agctgagatt tgtaatttat
      361 atcaaattcc ttatttacca ggttgtatga caattactga gataaaggag gcacttactg
      421 ctggcgtaga tatcattaaa ctattcccag gttctgcttt tggtccatcc attgtaaaag
      481 cctatcaagc tccattacca cacgtaaata taatgcctac tggcggagta agtatagaga
      541 acttagaaga ttggtttgaa gtaggagttg ttgcagttgg tgtaggtggg aatttattgg
      601 cttctgttga aaaaggtgat tttgaagaag taagtcgagt agctagtaaa tatatagata
      661 agttttatga gataaagaat tattaggaga aaaaacaaat aatactctga aatgtaaaaa
      721 ataaatactg actctttac
//
LOCUS       DACGEU010000225          685 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.233, whole genome shotgun sequence.
ACCESSION   DACGEU010000225 DACGEU010000000
VERSION     DACGEU010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 685)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 685)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..685
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.233"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            119..322
                     /locus_tag="IXR40_002924"
     CDS             119..322
                     /locus_tag="IXR40_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HAQ4362693.1"
                     /translation="MKHCVILGILGTCLAGIGTGIDVDAATYYGNGLYCNKEKCWVNW
                     GQSWSEGLKRWGDNLFGSFSGGR"
     gene            322..672
                     /locus_tag="IXR40_002925"
     CDS             322..672
                     /locus_tag="IXR40_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HAQ4362694.1"
                     /translation="MTSINIDHTKKVIHELYNSLMTRPNQTKALLDITDVLFQVYKKI
                     DTAKYPEILVNKLVNYIYIVGFDNKIRFIDNDEKLLIELGDISKKAGINSKYKANFTD
                     KSQFYSYSETMPQR"
BASE COUNT          285 a           69 c          115 g          216 t
ORIGIN      
        1 cattgttata taataaaatg ttatataata aaattactaa tgatatttaa tattacaagc
       61 aatcttaaga aattcgaaaa ggaaaaaatg attatgaaaa agaaagaaaa agaaagtatt
      121 gaaacattgt gttattctag gaatattagg aacttgtcta gctggcattg gtacaggaat
      181 agacgttgac gcagctactt actatggaaa tggtctttat tgtaacaaag aaaaatgttg
      241 ggtaaattgg ggacaatcat ggtcagaagg gttaaaacgt tggggagata atctttttgg
      301 tagttttagt ggaggacgat aatgacttca ataaacattg atcacacaaa aaaagtcata
      361 catgaattat acaatagttt aatgacacga cctaatcaga cgaaagcatt attagatatt
      421 actgatgttt tatttcaggt atataaaaaa attgatacag caaaatatcc tgaaattctt
      481 gtaaataaat tagttaatta tatttacatc gtgggttttg ataataaaat acgctttatt
      541 gataatgatg aaaaattatt aatagaatta ggggatattt ctaaaaaagc tggaattaat
      601 agtaaataca aagcaaactt tacagataaa tcgcaatttt atagttattc agaaacaatg
      661 cctcaacgat aaaatatagt atact
//
LOCUS       DACGEU010000226          666 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.234, whole genome shotgun sequence.
ACCESSION   DACGEU010000226 DACGEU010000000
VERSION     DACGEU010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 666)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 666)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..666
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.234"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            49..>666
                     /locus_tag="IXR40_002926"
     CDS             49..>666
                     /locus_tag="IXR40_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAQ4362695.1"
                     /translation="MPERPLIVFEATGIYSRPVEKFFQDHHFSYCLLNPLEAKKQMEE
                     NTLCSWKTDKSDAHRLAQTHLKNQRQPKEVQSNFYLEMRDLARFYQEIEKKITRLRMD
                     LHNCLQLTFPELEQFFLNRLTPYALILIRLFPHPDFVLASTRTKIKNKLINETRKKIS
                     ANRAEQKADQIIHYAQCAYPAVEKDSIHCQKTIYYAELLQDLLEQK"
BASE COUNT          227 a          149 c          116 g          174 t
ORIGIN      
        1 gaacacactc aaagaggatt tcatgcatta ctcgaagaga tccagcactt gcctgaacgt
       61 ccattgattg tttttgaagc aacggggatt tattccagac cagtcgaaaa gttctttcaa
      121 gatcatcact tttcttactg tttgttaaac ccgttagaag cgaaaaaaca gatggaagaa
      181 aacaccttat gcagttggaa aacagataaa tcggatgccc atcggctcgc acagactcat
      241 cttaaaaatc aacgtcagcc aaaagaagta caaagcaatt tttacttaga gatgcgcgat
      301 ttagcccgtt tttatcaaga aattgagaag aaaatcactc gtctgcgcat ggatttacac
      361 aactgccttc agttgacttt tccagagctt gaacagttct ttttaaacag gctgacccct
      421 tacgcattga tattgatccg tctttttccc catccagatt ttgtattggc atctactcgg
      481 acaaaaataa aaaataaact gatcaacgaa acacggaaaa aaatctccgc gaatcgtgcc
      541 gagcaaaagg cagatcaaat catccactat gcacagtgtg cctatccagc tgttgaaaaa
      601 gacagtatcc actgtcaaaa aacgatctat tacgctgaac ttctccaaga tttactcgaa
      661 caaaaa
//
LOCUS       DACGEU010000227          666 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.235, whole genome shotgun sequence.
ACCESSION   DACGEU010000227 DACGEU010000000
VERSION     DACGEU010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 666)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 666)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..666
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.235"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            49..>666
                     /locus_tag="IXR40_002927"
     CDS             49..>666
                     /locus_tag="IXR40_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAQ4362696.1"
                     /translation="MPERPLIVFEATGIYSRPVEKFFQDHHFSYCLLNPLEAKKQMEE
                     STLRSWKTDKSDAHRLAQTHLKNQRQPKEVQSNFYLEMRDLARFYQEIEKKITRLRMD
                     LHNCLQLTFPELEQFFSNRLTPYALTLIRLFPHPDFVLASTRTKIKNKLINETRKKIS
                     ANRAEQKADQIIHYAQCAYPAVEKDSIHCQKTIYYAELLQDLLEQK"
BASE COUNT          225 a          154 c          118 g          169 t
ORIGIN      
        1 gaacacactc aaagaggatt tcatgcatta ctcgaagaga tccagcactt gcctgagcgt
       61 ccattgattg tttttgaagc aacggggatt tattccagac cagtcgaaaa gttctttcaa
      121 gatcatcact tttcttactg tttgttaaac ccgttagagg cgaaaaaaca gatggaagaa
      181 agcaccttac gcagttggaa aacagataaa tcggatgccc accggctcgc acagactcat
      241 cttaaaaatc aacgtcagcc aaaagaagta caaagcaatt tttacttaga gatgcgcgat
      301 ttagcccgtt tttatcaaga aattgagaag aaaatcactc gtctgcgcat ggatttacac
      361 aactgccttc aattgacttt tccagagctt gaacagttct tttcaaacag gctgacccct
      421 tacgcattga cattgatccg tctttttccc catccagatt ttgtattggc atctactcgg
      481 acaaaaataa aaaataaact gatcaacgaa acacggaaaa aaatctccgc gaatcgtgcc
      541 gagcaaaagg cagatcaaat catccactat gcacagtgtg cctatccagc tgttgaaaaa
      601 gacagtatcc actgtcaaaa aacgatctat tacgccgaac ttctccaaga tttactcgaa
      661 caaaaa
//
LOCUS       DACGEU010000228          647 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.236, whole genome shotgun sequence.
ACCESSION   DACGEU010000228 DACGEU010000000
VERSION     DACGEU010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 647)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 647)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..647
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.236"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(249..548)
                     /locus_tag="IXR40_002928"
     CDS             complement(249..548)
                     /locus_tag="IXR40_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HAQ4362697.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
BASE COUNT          217 a          113 c           72 g          245 t
ORIGIN      
        1 ttccaatttt taacttacaa aaatgcaaca ttaataaata acgatagttt cataaaatac
       61 acttttaatt aacattatta gtttatacta gctgtttttg tgttaattaa aggataaaat
      121 acaatataaa gaaacatctg tttctttatt tagaataaaa aaatacagac tctgttcaaa
      181 taaatgaacc tagcctgcat tatgagattg actatacttt ttaattcatt gagatgaata
      241 actcgttttt ataaatgccc aaaagtaatc ggtgccgaag ccattcctcg acctaattct
      301 ttttcaaatt ttcctattgt tgatatctcc atataaaacg gtgatactgg tttagacaat
      361 tctcccctga ttgctaacgg acgtaaacta cgttccaaat tatttatgac tttaggataa
      421 tactgacctt tttctaagcc tgtctttgcg tctatcaaaa gtatacgttc cttttctttg
      481 atctctggat ttaaaacgag atcatataat tttagtacca tgttttctat ttcttcactt
      541 ttagacatca cgatttcctc ccaaaaatat atttcttccc actacattct ataaacaaag
      601 tatacgctac atctagattt ttttaaatca ttactggatt gttaaaa
//
LOCUS       DACGEU010000229          626 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.237, whole genome shotgun sequence.
ACCESSION   DACGEU010000229 DACGEU010000000
VERSION     DACGEU010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 626)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 626)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..626
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.237"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            <1..>626
                     /locus_tag="IXR40_002929"
     CDS             <1..>626
                     /locus_tag="IXR40_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HAQ4362698.1"
                     /translation="RNLDSRTRFEQEEIKVKTILQLKKEFKLNLLLSIAQLAKSTYYY
                     WVKKLDKPDKYSKIKQEITAIVKESRNSYGYRRVTLALKMKGYTINHKTVRKLMSQMG
                     LTCQIRIKRYKSYKGTVGKIAKNVLKRNFSVDTPNKKWVTDVTEFKIKGRKIYLSPIL
                     DLFNGEIISYSISTSPTYKLIEEMLQQAIKKKGTEGSLILHSDQGWQY"
BASE COUNT          272 a           89 c          102 g          163 t
ORIGIN      
        1 agaaaccttg attcaagaac aagatttgag caagaagaaa tcaaggttaa aacaatcctt
       61 cagctcaaaa aagaatttaa attgaatcta ttactttcaa ttgcacaatt agcgaagtca
      121 acttattatt actgggtaaa aaaattagat aagccagata aatatagcaa gataaagcaa
      181 gaaattacag cgattgtaaa agaatcaaga aactcttatg gttatcgtag agtcacttta
      241 gcgttaaaga tgaaaggata tacaatcaat cataaaacag ttagaaaatt aatgtcccaa
      301 atgggactta cctgtcaaat ccgaataaag cgatataaat cttataaagg aacagtagga
      361 aaaattgcca agaatgtgtt aaaacgaaat ttttcagtag atacacccaa taaaaaatgg
      421 gtgacagacg tcactgaatt caagataaaa ggaagaaaaa tctatctatc tcctatactt
      481 gatttattta acggagaaat aattagttat agtatatcaa ctagtccaac atataaactg
      541 attgaagaaa tgcttcaaca agcaattaaa aaaaagggaa ctgagggttc actgattcta
      601 cattcagatc aaggatggca gtatca
//
LOCUS       DACGEU010000230          575 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.238, whole genome shotgun sequence.
ACCESSION   DACGEU010000230 DACGEU010000000
VERSION     DACGEU010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 575)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 575)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..575
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.238"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
BASE COUNT          186 a           81 c           81 g          227 t
ORIGIN      
        1 tttttcttga tgtgatatcc ttgtcttttt tgtaatgttt ttaacttatt gcttttgcaa
       61 aatttattta cctgttttct ggatcaacga tagtgtacat tatgctatcc ttgtttggat
      121 tttaggacgt ttaaagaggc acttttttac ataacttaat ccatagacct tttaagcatg
      181 ctgtgagata ataataaaga agagtttaaa gcgcacccca aaccacttcc ccataagtgt
      241 attacgcttt aaactctttt atatttgaat tcactaagaa gcataccata tttttgaaaa
      301 aaagtgagaa aaaaggctta taattaggat ttagagtaat taattagatg tttattttat
      361 aggactgata ctatagatta caaatagtat cgtatttcgc aatcttaaaa ttatcttctt
      421 actgtgaata agataataaa atttgtattt gtccttttta ggtaacttat tttaatctat
      481 atacctttct ggatcaacga aagtatactt tatatagtca taacgccgat ggtaactatg
      541 cactgtaacg ataatgctgc taaaatatct tttta
//
LOCUS       DACGEU010000231          564 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.239, whole genome shotgun sequence.
ACCESSION   DACGEU010000231 DACGEU010000000
VERSION     DACGEU010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 564)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 564)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..564
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.239"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(41..126)
                     /locus_tag="IXR40_002930"
     tRNA            complement(41..126)
                     /locus_tag="IXR40_002930"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(90..92),aa:Leu,seq:taa)
     gene            complement(143..214)
                     /locus_tag="IXR40_002931"
     tRNA            complement(143..214)
                     /locus_tag="IXR40_002931"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(180..182),aa:Gly,seq:gcc)
     gene            complement(226..298)
                     /locus_tag="IXR40_002932"
     tRNA            complement(226..298)
                     /locus_tag="IXR40_002932"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(263..265),aa:Thr,seq:tgt)
     gene            complement(316..397)
                     /locus_tag="IXR40_002933"
     tRNA            complement(316..397)
                     /locus_tag="IXR40_002933"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(361..363),aa:Leu,seq:tag)
     gene            complement(405..477)
                     /locus_tag="IXR40_002934"
     tRNA            complement(405..477)
                     /locus_tag="IXR40_002934"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(442..444),aa:Lys,seq:ttt)
     gene            complement(481..553)
                     /locus_tag="IXR40_002935"
     tRNA            complement(481..553)
                     /locus_tag="IXR40_002935"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(518..520),aa:Val,seq:tac)
BASE COUNT          145 a          160 c          135 g          124 t
ORIGIN      
        1 aaacactcta tccagttgag ctatgggcgc atatttgaaa tgccgaggac cggaatcgaa
       61 ccggtacggt gatcactcac cgcaggattt taagtcctgt gcgtctgcca gttccgccac
      121 cccggcgcga ttgctttggc aaagcggaaa acggggttcg aacccgcgac ccccaccttg
      181 gcaaggtggt gctctaccac tgagctattt ccgcgtgttt aaagatgccg gctaaaggac
      241 ttgaaccctc gaccctctga ttacaaatca gatgctctac caactgagct aagccggcat
      301 gtaaaactta aattatgcgg gtgaagggac ttgaaccccc acgccgtaag gcgctagatc
      361 ctaaatctag tgcgtctgcc aattccgcca cacccgcaaa aatatgagcc gtacagggct
      421 cgaacctgtg accctctgat taaaagtcag atgctctacc aactgagcta acggctcata
      481 tggaggttaa cgggatcgaa ccgctgaccc tctgcttgta aggcagatgc tctcccagct
      541 gagctaaacc tccatggata actt
//
LOCUS       DACGEU010000232          551 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.240, whole genome shotgun sequence.
ACCESSION   DACGEU010000232 DACGEU010000000
VERSION     DACGEU010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 551)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 551)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..551
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.240"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            <1..>551
                     /gene="tnpB"
                     /locus_tag="IXR40_002936"
     CDS             <1..>551
                     /gene="tnpB"
                     /locus_tag="IXR40_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family element transposase accessory
                     protein TnpB"
                     /protein_id="HAQ4362699.1"
                     /translation="ATISRHSSGKYYISLLCKEEVRELPKSNSAVGIDLGIIDFAILS
                     TGQKFDNNKFTSKMEKKLKREQRKLSRRALLAKQKGINLFEARNYQTQKRKVARLHEK
                     VMNQRTDFLNKLSTEIIKNHDIICIEDLNTKGMLRNHKLAKSISDVSWSSFVSKLQYK
                     ADWYGRKIIKVDKWFPSSQICSN"
BASE COUNT          203 a           87 c           95 g          166 t
ORIGIN      
        1 gctacaatat cacgtcattc tagcggtaaa tattatattt ctttgttatg caaagaagaa
       61 gttcgcgaac tacctaaatc taattctgct gttggtattg acctaggtat tatagacttt
      121 gcaattcttt ctaccggtca aaaatttgat aataataaat ttacgtccaa aatggaaaag
      181 aaactcaaac gtgaacaacg taagttgtca agacgtgcct tattagctaa acaaaaaggt
      241 atcaatctgt ttgaagctag aaattatcaa acacaaaaac gtaaagtagc acgattgcat
      301 gaaaaagtaa tgaatcaacg tactgatttt ctgaataagt tgagtacaga aattatcaaa
      361 aatcacgata tcatctgtat tgaagactta aacacaaaag gcatgttgcg taatcataaa
      421 ctagcaaaaa gtatttcgga tgtttcttgg tctagttttg tgtctaaatt acaatacaag
      481 gctgactggt acggtcggaa aatcatcaaa gtagataagt ggtttccatc tagccaaatc
      541 tgttcgaatt g
//
LOCUS       DACGEU010000233          530 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.241, whole genome shotgun sequence.
ACCESSION   DACGEU010000233 DACGEU010000000
VERSION     DACGEU010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 530)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 530)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..530
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.241"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            312..428
                     /locus_tag="IXR40_002937"
     CDS             312..428
                     /locus_tag="IXR40_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010768364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HAQ4362700.1"
                     /translation="MIGLNAISAKYCKFKAFVEKFTERQTDKIIQYHITYTD"
BASE COUNT          224 a           50 c           69 g          187 t
ORIGIN      
        1 taataaagaa ttgaacttct gagaaaacaa agaatctttt ttcttttttt gaattgactc
       61 atggattggc gttaaaattt tattttgaaa aagttatttc tggtttaact caaaaaaaga
      121 gatatgaatc taatagtgat agaaaggatg ttatttttca tgaaatggtt gttttagatt
      181 taatacatat aactaataaa tgctattgaa tgtatttaaa ctaattaaca aaagaatttg
      241 aattgttaat aaaatccaat aaaatatatt aataaagtag atagaaataa aaaaacaaag
      301 actaaacata tataattgga ttaaacgcaa tatctgcaaa atattgtaaa tttaaagcct
      361 ttgtagaaaa atttactgaa agacaaactg ataagattat tcagtatcat attacctata
      421 ctgattaaaa ttttttgaaa cgggatacta aataaaaaat ttatttataa cagaactaat
      481 tatttaatgc ggatgcgcca atacttggtc ctgcaagagc tatttatttt
//
LOCUS       DACGEU010000234          529 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.242, whole genome shotgun sequence.
ACCESSION   DACGEU010000234 DACGEU010000000
VERSION     DACGEU010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 529)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 529)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..529
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.242"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            33..>529
                     /locus_tag="IXR40_002938"
     CDS             33..>529
                     /locus_tag="IXR40_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEf1 family transposase"
                     /protein_id="HAQ4362701.1"
                     /translation="MNDFTTEIVQTLVTKGDLNELFRSHLEKAINTLLRTELTAFLDY
                     EKYDRTGFNSGNSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLET
                     TIIHLFEKGVTMSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKSRALNDKYVAI
                     FMDAT"
BASE COUNT          194 a           98 c           87 g          150 t
ORIGIN      
        1 gacaaccaat tcacagaaaa gaggacttcc ctatgaatga ttttactaca gaaattgtgc
       61 aaactctagt cactaaaggc gatttaaatg aattattccg ttcgcactta gaaaaagcga
      121 taaacacact cctacggact gaattaacgg cttttttaga ttacgaaaaa tatgatcgca
      181 ctggttttaa ttcaggtaat tcgagaaacg gttcttactt tcgatcaatc aaaaccgaat
      241 atggtgaatt aacattggaa atacctagag atcgtaatgg tgagtttaaa caacaaactt
      301 taccagccta caaaagaaca aacgatacat tggaaaccac tattatccat ttattcgaaa
      361 aaggtgttac gatgtctgaa attgctgatt tgatcgaaaa aatgtacggt catcactata
      421 ctccacaaac catgtccaac atgactaaag ttctgactga agaagtaaat gcctttaaat
      481 ccagagcctt aaatgataag tatgtcgcta tttttatgga cgctactta
//
LOCUS       DACGEU010000235          518 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.243, whole genome shotgun sequence.
ACCESSION   DACGEU010000235 DACGEU010000000
VERSION     DACGEU010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 518)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 518)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..518
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.243"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(1..444)
                     /locus_tag="IXR40_002939"
                     /pseudo
     CDS             complement(1..444)
                     /locus_tag="IXR40_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321168.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          200 a           81 c           65 g          172 t
ORIGIN      
        1 atagcaataa aaataagata ttcatgtcta aaaaaacggc tttccaaatg atgaaatacc
       61 taaatctaac ttattaagaa agttgaaatt tttatattca ggaaaccatt tattaatttc
      121 atgtgcagca cgtaatgcat tccctggagt tgtcaaagag aaaattaatt ctgctaagct
      181 tattattgaa aatactgata acttataatt atatcgtcca ttgacaatca aatataaact
      241 aactatactt gttagaacaa aaaaacaggc gttgacttgt tcttgattag ttaaaaatat
      301 caataaagga atacttaccc aatatatttt tctatttatt tcttctcctc ttaagagttg
      361 aaaaaacgga taaaaagtta gtaaactaaa tgctactggc cactgatagt tcaaggtggt
      421 tgctctccaa ccggtttccc ccattactgt caatggtatt aaacagtata tagagcaaac
      481 caataataaa tttttaacat ttattttctc aaaaacat
//
LOCUS       DACGEU010000236          513 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.244, whole genome shotgun sequence.
ACCESSION   DACGEU010000236 DACGEU010000000
VERSION     DACGEU010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 513)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 513)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..513
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.244"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(107..>513)
                     /locus_tag="IXR40_002940"
     CDS             complement(107..>513)
                     /locus_tag="IXR40_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_465591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HAQ4362702.1"
                     /translation="TPENHFSNQISLNVYSRGMGGLGLPGDLSSVSRFVKATFTKMNA
                     ASGDSESESISQFFHILGSVEQQKGVCDTGEGKYEYTIYSSCCNVDKGIYYYRTYEDS
                     QITAVNMNKEDLDRHELVSYPVIKEQQINYVN"
BASE COUNT          162 a          102 c           78 g          171 t
ORIGIN      
        1 atcatccata aaatggactt tgtctacagt ctgagacacg acctaaagat cgtgtctaat
       61 tatgactgta tcagaaaata tgataccaaa cggatctatt cattaattaa ttgacatagt
      121 ttatctgttg ctcttttatg actggataac tgaccaattc atgacgatcc aagtcttctt
      181 tattcatatt tacagcagta atttgactgt cttcatacgt acgataataa taaatccctt
      241 tatcaacgtt acagcaagaa gaataaatcg tatattcgta ttttccttct ccagtatcgc
      301 atactccttt ttgttgctcg actgagccta gtatatgaaa aaattgactg atactttcag
      361 attctgaatc acctgatgca gcattcattt tagtaaatgt ggcttttaca aatcgagaaa
      421 cagaagagag atctccaggt aagcccaatc ctcccatccc acgactataa acattcaagc
      481 tgatctggtt tgaaaaatga ttttctggtg ttc
//
LOCUS       DACGEU010000237          508 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.245, whole genome shotgun sequence.
ACCESSION   DACGEU010000237 DACGEU010000000
VERSION     DACGEU010000237.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 508)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 508)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..508
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.245"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
BASE COUNT          229 a           69 c           81 g          129 t
ORIGIN      
        1 aattccttag gcagcttttg ctgtgtagaa aggaataaat aataacgaaa gttcaaaagc
       61 taatgccgac tattctagac attaaagaag acgaaaacga acgataaaga aagaaaagtt
      121 atgaataatc gtttattgaa aaaaacttga aaaaatacaa aaaattcgtt gaccaagcta
      181 aatttagttg gtatattatt acttgtccaa aagacagaag aaaatattta ttcaaaaaca
      241 taacaaaaaa gttattgaca tgttactaac gacatgataa gataactgag tcgttaaaaa
      301 agaaccactt gcgaagcttg attctatcga aaaaaacttc aaaaaagtta ttgacaaata
      361 acaaacgata agttatgata aatgagttgc cgaaagattt cgaaaaacga aatcgaaaaa
      421 aacttttaaa aaagagttga caatcgcttg tctctctgat atgatataaa agttgctacg
      481 gcagccaaaa atgaatcggg aaacactc
//
LOCUS       DACGEU010000238          493 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.246, whole genome shotgun sequence.
ACCESSION   DACGEU010000238 DACGEU010000000
VERSION     DACGEU010000238.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..493
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.246"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..159)
                     /locus_tag="IXR40_002941"
     CDS             complement(<1..159)
                     /locus_tag="IXR40_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAQ4362703.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNS"
     gene            complement(178..333)
                     /locus_tag="IXR40_002942"
                     /pseudo
     CDS             complement(178..333)
                     /locus_tag="IXR40_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392734.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="(4Fe-4S)-binding protein"
     gene            409..>493
                     /locus_tag="IXR40_002943"
     CDS             409..>493
                     /locus_tag="IXR40_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAQ4362704.1"
                     /translation="MPRRQRRTYSKEFKQQIVDLYLAGKPCA"
BASE COUNT          168 a           97 c           58 g          170 t
ORIGIN      
        1 agaattagaa ctttcatata aagccttttc tatttcattg cttgatttca ttattgttaa
       61 acaagaatac aagcaagaaa gaactatagt taatatgata aaaattatta aagttctatt
      121 tttctttctt gtaatatatg ctatagcatt ttttatcact ttcctaacta ctcctttcta
      181 ttttcttact ccataactaa ttgcatccac tggacaagca tttttacatc gtccacatct
      241 gatacactcc agatgattgc aattctcaac tgaatcttta ttcatttggc aaactttttt
      301 acattttcca caattaatac acttatcctt atcctgaatc ggctacacta gactagacag
      361 aaaaaataag gtgtgtagaa taataaaaaa cacactggag gatttttcat gccaagacgt
      421 caacgaagaa cctattcaaa agaattcaaa caacaaatcg tcgatctcta tctcgctggt
      481 aagccttgcg cag
//
LOCUS       DACGEU010000239          493 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.247, whole genome shotgun sequence.
ACCESSION   DACGEU010000239 DACGEU010000000
VERSION     DACGEU010000239.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..493
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.247"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(54..>493)
                     /locus_tag="IXR40_002944"
     CDS             complement(54..>493)
                     /locus_tag="IXR40_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAQ4362705.1"
                     /translation="KKAEGSPCFLLYQTFPGIGALTAALLLGELGDITRFKTHKQLNA
                     FVGIDIRRYHSGKYTGQDRINKRGNPKARKIIFFTIRNMIRQQRAAPNHIVDYYYKLK
                     KQPIPKKDKVATVACMNKLLKCMHAMVRAHTEYDYAYAVSVDH"
BASE COUNT          133 a           92 c          115 g          153 t
ORIGIN      
        1 tcgtaaaaaa ttttcgatct gggcaaagaa gtggtatact gtaagtggtt tagttaatgg
       61 tccactgaga ccgcgtacgc atagtcgtac tctgtatgtg ccctaaccat agcgtgcata
      121 catttcagaa gcttgttcat acaagcaact gtggcaacct tatctttctt agggataggt
      181 tgctttttta atttgtagta ataatcgaca atatgattag gagctgcgcg ttgctggcga
      241 atcatatttc gaatggtgaa gaaaataatt ttccgtgctt tgggattacc acgcttattg
      301 atgcggtctt ggccagtata cttacctgaa tgataccgtc ggatgtcgat tccgacaaag
      361 gcattcaatt gtttatgggt tttaaatcgt gtgatatctc ctaattcacc gagcaataaa
      421 gcggctgtga gtgcgccaat cccagggaac gtttggtaca acaaaaagca aggagagcct
      481 tcggcttttt tga
//
LOCUS       DACGEU010000240          488 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.248, whole genome shotgun sequence.
ACCESSION   DACGEU010000240 DACGEU010000000
VERSION     DACGEU010000240.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 488)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.248"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..>488)
                     /locus_tag="IXR40_002945"
     CDS             complement(<1..>488)
                     /locus_tag="IXR40_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="beta-1,6-N-acetylglucosaminyltransferase"
                     /protein_id="HAQ4362706.1"
                     /translation="DYPRINRNNTTAFKIFRAIINRCLRMIKLPPKIRHHKFDLYHGS
                     QWWALSKECLTELIQMYEQNQQDYLNFKIGMFAPDEKFFHTLFFNSSFKNKNVIGGPD
                     LPLELKNIEETTLQTSKLANIHIIDPSMNKWFDERDIDQIKESEKLFVRKVKSDYSDK
                     LL"
BASE COUNT          158 a           70 c           66 g          194 t
ORIGIN      
        1 taatagttta tcagagtaat ccgatttaac ttttcttaca aataattttt cactttcttt
       61 tatttgatct atatcccttt catcaaacca tttgttcatg gaaggatcaa taatatgaat
      121 atttgctaat ttcgaagttt gtaaagtagt ttcttcaata tttttcaatt caagtggtaa
      181 atctggtcct ccaataacat ttttattttt gaacgaggaa ttaaaaaaaa gtgtatgaaa
      241 aaatttttca tctggggcaa acatacctat tttaaaattc aggtagtctt gttgattttg
      301 ttcatacatt tgtattaatt ctgttaggca ttctttcgac aaagcccacc attgagaacc
      361 atgatacaaa tcaaatttat ggtgtctaat ttttggggga agtttaatca tcctcagaca
      421 acgattaatt atagctctaa aaattttaaa tgcagttgtg ttattcctat taattctagg
      481 ataatcat
//
LOCUS       DACGEU010000241          483 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.249, whole genome shotgun sequence.
ACCESSION   DACGEU010000241 DACGEU010000000
VERSION     DACGEU010000241.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 483)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.249"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            1..483
                     /locus_tag="IXR40_002946"
                     /pseudo
     CDS             1..483
                     /locus_tag="IXR40_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS3-like element ISEfa8 family transposase"
BASE COUNT          179 a           97 c          100 g          107 t
ORIGIN      
        1 tacgccttct tctttcgata aatggatgaa gcaagcacaa tcaacgggct cattcaaaga
       61 aagagacaac ttaacaccag aacaagcaga attgatcgca ctaagaaaga aaaataagca
      121 actcgaaatg gagaatgata ttttaaagca agcggcgctg atattcggac gaaaagacaa
      181 gtaattgatg ccaacaagca taaatattcc atatcagcga tgtgcaaaat tctaaatatt
      241 tctcgtcaaa cctactatta tcaagcgaaa ccgatcgaaa atgagtccga cttagaagag
      301 atcgttcagg aagagtttat tcgaaaccga aaggcttacg gtacccgaaa attgaagaag
      361 tgtttagcaa agcgtgggct tcaactcagt cggcgccgaa tcggtcgaat catgaaacgc
      421 cgcggattga catctaccta tacgatcgct cattttaaag ggcaacgaac agcttgtaat
      481 gaa
//
LOCUS       DACGEU010000242          470 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.250, whole genome shotgun sequence.
ACCESSION   DACGEU010000242 DACGEU010000000
VERSION     DACGEU010000242.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 470)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.250"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            <1..>470
                     /locus_tag="IXR40_002947"
     CDS             <1..>470
                     /locus_tag="IXR40_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3-like element IS1485 family transposase"
                     /protein_id="HAQ4362707.1"
                     /translation="ALSKRGIQISRRKISRIMKNRGLKSSYTVAYFKVHHSTCNEAKT
                     TNVLNRKFLRDNPLEAIVTDLTYVRVGKKWNYVCFILDLFNREILGYSCGEHKDAVLV
                     KKAFSRIKQPLTEVEIFHTDRGKEFDNQAIDELLTTFDINRSLSHKGCPFDNAV"
BASE COUNT          167 a           78 c           88 g          137 t
ORIGIN      
        1 aagccttatc aaaacgaggc attcagatca gccgacgaaa aattagtaga atcatgaaaa
       61 atagaggatt aaaatcgagc tatactgttg cttattttaa agtacatcat tctacttgca
      121 atgaagccaa aacgacaaac gtattgaatc gtaaattctt aagagacaac ccattagaag
      181 cgatcgtaac agacttgact tatgtacgag tcgggaaaaa atggaattat gtctgtttca
      241 ttttggatct gttcaatcga gaaattctcg gctattcttg tggagaacat aaagatgccg
      301 ttctagtaaa aaaagcattt agccgtatca aacaacctct gacagaggtt gagatttttc
      361 atactgatcg tggaaaagag tttgataacc aagctattga tgaattatta acaacttttg
      421 acatcaatcg atcattgagt cataaaggct gtccttttga taatgccgta
//
LOCUS       DACGEU010000243          462 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.251, whole genome shotgun sequence.
ACCESSION   DACGEU010000243 DACGEU010000000
VERSION     DACGEU010000243.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.251"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..430)
                     /locus_tag="IXR40_002948"
     CDS             complement(<1..430)
                     /locus_tag="IXR40_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAQ4362708.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRA"
BASE COUNT          132 a           92 c           59 g          179 t
ORIGIN      
        1 ctgctcttaa acgaataact tcttcttcaa gagactcatc tttaagtttt ttaggaatgt
       61 ttagcttgga attcatacta atttttctgc cccttttttg gctctcaagt gaagaagcac
      121 cgccttcttc atattgctct atccatttac ttagagttct atttgaaccg atattaaatt
      181 ttttagcagt ttcttggata gaaagaccat ttgtttccat atattctata acatcaagtt
      241 taaattttgt agtgtagctt ttgccacctc caaccaagcc ttcccaacca tgatagttat
      301 aaatccttac ccaatgtcta accagtgtac gatttatttg atatttatgt gcaagatatt
      361 tgtagccgcc ttcgttattt aaatagtctg aaactacttt tttcttaaaa acaaatgtat
      421 atttccgcaa aaaaagcacc ccttttaatt agatttctag tc
//
LOCUS       DACGEU010000244          408 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.253, whole genome shotgun sequence.
ACCESSION   DACGEU010000244 DACGEU010000000
VERSION     DACGEU010000244.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 408)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 408)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..408
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.253"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            <1..390
                     /locus_tag="IXR40_002949"
     CDS             <1..390
                     /locus_tag="IXR40_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAQ4362709.1"
                     /translation="KDRKEICDDFKAVYQANSKEEANTFLSGMIEKWKKNYPKVTQSL
                     IENQDLLTFYDFPPSIRRTIYSTNLIESFNKQIKRYSRRKEQFQNEESLERFLVSIFD
                     TYNQKFLNRSHKGFQQVTDTLVSMFTE"
BASE COUNT          158 a           73 c           64 g          113 t
ORIGIN      
        1 aaagaccgaa aagaaatctg tgatgacttt aaggctgttt atcaagctaa ctcaaaagaa
       61 gaagcgaata ccttcttatc cggcatgatt gagaaatgga agaaaaacta tcctaaagtg
      121 acgcagtcac tcatagaaaa ccaagactta ttaacttttt atgattttcc acctagcatt
      181 cgtagaacca tttactcaac caatctaatc gagtctttca ataagcaaat taaaagatac
      241 agccgtagaa aagagcagtt tcaaaatgaa gaatcactag aacgctttct agtcagcatt
      301 tttgatacat acaatcaaaa atttctaaac agaagccata aaggttttca acaggtaacc
      361 gatacattag tttcaatgtt tactgagtaa ctaattattt tgcaggag
//
LOCUS       DACGEU010000245          403 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.254, whole genome shotgun sequence.
ACCESSION   DACGEU010000245 DACGEU010000000
VERSION     DACGEU010000245.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 403)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 403)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..403
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.254"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
BASE COUNT          150 a           50 c           49 g          154 t
ORIGIN      
        1 aatttaacgc aaaacttatt aaaaaaagac aattctagta tactgaaaat agaattaaaa
       61 aaggagaaca acaaatctat gaaaataagt aaaaaagcat ttcttttagt agttcttatc
      121 ttacttagta ctttatattc agtaaatttt atgagaaatg ctcaagaaat ttatacaaca
      181 ggtgatttat cttttcatct ttcacgaatc aaagggttat cttctatttt tgaagggcca
      241 atcaactata caacatttaa caattatgga gatggactga actattttta tccttttctt
      301 acaataattc ctgcagtcgt tttttatgga atttcaaata acttaatatt aagttatgtt
      361 ctatatattt ggttattaaa tatttgtacg attctgatta gtt
//
LOCUS       DACGEU010000246          392 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.255, whole genome shotgun sequence.
ACCESSION   DACGEU010000246 DACGEU010000000
VERSION     DACGEU010000246.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 392)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 392)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..392
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.255"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            <1..>392
                     /locus_tag="IXR40_002950"
     CDS             <1..>392
                     /locus_tag="IXR40_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="HAQ4362710.1"
                     /translation="QDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHTTIYRWVQEY
                     GKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWLRKKRDTQA
                     AYAFLKRLVKQFDEPKVVVTDKAPSITS"
BASE COUNT          130 a           64 c           82 g          116 t
ORIGIN      
        1 gcaggatgtg attattgtag ccgtgggcta ctatcttcgt tataacctta gctatcgtga
       61 agttcaagaa atcttatatg atcgtggcat taacgtttct catacgacga tttatcgttg
      121 ggtgcaagaa tatggcaaac tactctatca aatttggaaa aagaaaaata aaaaatcctt
      181 ttattcatgg aaaatggatg aaacgtacat caaaattaaa ggaaaatggc attatttgta
      241 tcgagccatc gatgcagatg gtttaacctt ggatatttgg ttacgtaaaa aacgggacac
      301 acaagcagcc tatgcttttc ttaagcggtt agtgaagcag tttgatgaac cgaaggttgt
      361 agtcacagat aaagccccct ctattacaag tg
//
LOCUS       DACGEU010000247          375 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.256, whole genome shotgun sequence.
ACCESSION   DACGEU010000247 DACGEU010000000
VERSION     DACGEU010000247.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 375)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 375)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..375
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.256"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..132)
                     /locus_tag="IXR40_002951"
     CDS             complement(<1..132)
                     /locus_tag="IXR40_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAQ4362711.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     "
BASE COUNT          132 a           69 c           76 g           98 t
ORIGIN      
        1 tcgtatgaat gaagcacctt cgatgtcatt ggcaacagag atttcagata agatagacaa
       61 ttgattgtcg tctgttaaaa aacaaacatc tagtttttca gagctaacgt caataccgac
      121 aaataatttc atggaagaag gacctccttt cgatataaat tttggaaaat gcttcgatac
      181 tgtgggattt cccagaaact cactgtatag ccacaacctc gcctaataga atacggtgat
      241 aaaagagcta gaagctgcct tccaaactac tatttgaaag tctagtccat tatcgaaaca
      301 gctaatgagt tggtagtgat aacagtggtt cgggtaacag actaaacagg gtagacaaac
      361 gctacaggag gaaat
//
LOCUS       DACGEU010000248          367 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.257, whole genome shotgun sequence.
ACCESSION   DACGEU010000248 DACGEU010000000
VERSION     DACGEU010000248.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 367)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 367)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..367
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.257"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            <1..>367
                     /locus_tag="IXR40_002952"
     CDS             <1..>367
                     /locus_tag="IXR40_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAQ4362712.1"
                     /translation="KIPHFSTFGKNYVRRFRETTVFEDIFAYILEQAVKAGFVTEDNL
                     YLDSTHIKANANKHKFTKEMTHDEAKAYQDELEDEINRQRIEAGKRPFTLDLEKEVKL
                     KERKISKADPESGYYVKGER"
BASE COUNT          137 a           61 c           80 g           89 t
ORIGIN      
        1 aaaatccccc atttctcaac ttttggaaag aattatgttc gccgatttag agaaacgacg
       61 gtgtttgagg atatttttgc ctatatttta gaacaagcag ttaaagcagg ttttgtaaca
      121 gaggataatt tgtatctgga ttctacccac atcaaagcta acgccaataa acataagttt
      181 acgaaagaaa tgacccatga tgaagcgaaa gcctatcagg atgaattaga agatgagatc
      241 aatcgtcaac gaatagaggc tggaaaacgc ccttttactt tggacttaga aaaggaagtg
      301 aagctgaaag aaagaaaaat aagtaaagct gatccggaaa gcggctacta cgtcaaaggc
      361 gaacgag
//
LOCUS       DACGEU010000249          346 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.258, whole genome shotgun sequence.
ACCESSION   DACGEU010000249 DACGEU010000000
VERSION     DACGEU010000249.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 346)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 346)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..346
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.258"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
BASE COUNT          113 a           48 c           92 g           93 t
ORIGIN      
        1 aaaatggtga tgtgcgactt ttttctgttc gtaaaaataa aaaaagttta cgaaaatgaa
       61 actaaactga acgattatga cgggcatgta atcaagatga aatgatttta taagcgcgta
      121 ttttgcgttc taagacgttt tagcgttcat ttcgtttagt tatcggcaca atcgttaaaa
      181 cacgtaagag aagcgagaat ggagcctgta aggcgactgg tagcgaaacg gcgtgttaga
      241 ttgtgcaagc cgagaactga atgaaatgaa gagcggaagc gtgaaataat ttcggcagga
      301 ggaggctcaa ggggttcggg gaatgaaatt ccctgaggtc ttttta
//
LOCUS       DACGEU010000250          337 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.259, whole genome shotgun sequence.
ACCESSION   DACGEU010000250 DACGEU010000000
VERSION     DACGEU010000250.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 337)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 337)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..337
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.259"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..250)
                     /locus_tag="IXR40_002953"
     CDS             complement(<1..250)
                     /locus_tag="IXR40_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362713.1"
                     /translation="MVYFNNVFIIIIFLAALISIYQFIFLISYHVPTGTPGLLARQGF
                     IEHRLFGVYTSPNVGAMFGYTSIILSLISVLISKITKTI"
BASE COUNT          136 a           50 c           41 g          110 t
ORIGIN      
        1 gaatcgtttt tgttattttt gaaattaata cactaattaa acttaaaata atagaagtat
       61 atccaaacat agctccaaca tttggacttg tatagacacc aaataaccga tgttcaataa
      121 aaccttgtct tgcaagtaat cctggcgttc ctgttgggac atgataagaa atcaaaaaaa
      181 taaattgata gatagatatt agcgcagcta aaaaaattat gataatgaaa acattattaa
      241 aatacaccat ttttttcttt ttttcctctt cactttgtga aaagtctgca ggaaaaatta
      301 ctatcaaagt aatcagcaaa tatccaaaat tataaat
//
LOCUS       DACGEU010000251          321 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.260, whole genome shotgun sequence.
ACCESSION   DACGEU010000251 DACGEU010000000
VERSION     DACGEU010000251.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 321)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 321)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..321
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.260"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..>321)
                     /locus_tag="IXR40_002954"
     CDS             complement(<1..>321)
                     /locus_tag="IXR40_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAQ4362714.1"
                     /translation="ITRHVWGDLMDEVEHLRLTDLNKSIYKKRKQTIERIFADAKEKH
                     GMRWTKYRGLEKVATHTMLVFAAMNLKKLATWLWKGKEPLFFCSKIRNEVDKKLFQAR
                     VTSL"
BASE COUNT           79 a           78 c           51 g          113 t
ORIGIN      
        1 tccaaactcg taactcgagc ttggaacagc tttttatcta cttcgtttcg aatttttgaa
       61 caaaaaaata aaggctcctt gcctttccat agccaggtgg ctaatttctt taaattcatt
      121 gcagcaaaca ctagcatcgt atgcgtcgcg actttttcca agcctcgata cttggtccaa
      181 cgcatcccat gcttttcttt tgcatccgca aatattcgtt caatcgtttg tttccgtttt
      241 ttgtaaattg atttattcag atctgttagg cgaagatgtt ccacttcatc catcagatct
      301 ccccaaacat gtctcgtgat g
//
LOCUS       DACGEU010000252          321 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.261, whole genome shotgun sequence.
ACCESSION   DACGEU010000252 DACGEU010000000
VERSION     DACGEU010000252.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 321)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 321)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..321
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.261"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            <1..317
                     /locus_tag="IXR40_002955"
     CDS             <1..317
                     /locus_tag="IXR40_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014834562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HAQ4362715.1"
                     /translation="IKIVLSASIPILIDQASEHRSLLLIVSIASAIITIIQSGMSAFN
                     YQDKVQTSTELLMKIEKEKLLYITKTSPYNKTDEENFHLIVTTLQTELNDIISDFNQV
                     NN"
BASE COUNT          130 a           47 c           38 g          106 t
ORIGIN      
        1 ttataaaaat agtcttatca gctagtatcc caatattaat tgatcaggct tccgaacaca
       61 ggtctttact attgattgtt tcaattgctt cagcaataat tacaattata caaagtggta
      121 tgtctgcatt taattatcaa gataaagtac agacttcgac agagttatta atgaaaattg
      181 aaaaagaaaa gttgttatat ataacgaaaa catccccata taataaaaca gatgaagaaa
      241 atttccattt aatcgttaca acccttcaaa ctgaattaaa tgatattatc tctgatttta
      301 atcaagttaa taactaaaaa t
//
LOCUS       DACGEU010000253          311 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.262, whole genome shotgun sequence.
ACCESSION   DACGEU010000253 DACGEU010000000
VERSION     DACGEU010000253.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 311)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 311)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..311
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.262"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(40..>311)
                     /locus_tag="IXR40_002956"
     rRNA            complement(40..>311)
                     /locus_tag="IXR40_002956"
                     /product="16S ribosomal RNA"
BASE COUNT           77 a           83 c           77 g           74 t
ORIGIN      
        1 ctgaacaaag taaaaacaaa ttgtgtagtc tccgtaatat tccttagaaa ggaggtgatc
       61 cagccgcacc ttccgatacg gctaccttgt tacgacttca ccccaatcat ctatcccacc
      121 ttaggcggct ggctccaaaa ggttacctca ccgacttcgg gtgttacaaa ctctcgtggt
      181 gtgacgggcg gtgtgtacaa ggcccgggaa cgtattcacc gcggcgtgct gatccgcgat
      241 tactagcgat tccggcttca tgcaggcgag ttgcagcctg caatccgaac tgagagaagc
      301 tttaagagat t
//
LOCUS       DACGEU010000254          309 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.263, whole genome shotgun sequence.
ACCESSION   DACGEU010000254 DACGEU010000000
VERSION     DACGEU010000254.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 309)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 309)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..309
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.263"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
BASE COUNT          110 a           34 c           56 g          109 t
ORIGIN      
        1 agtataaaaa tgaacaaaca taatagaaaa ataacgaata acaaagaact gatcttgtta
       61 ctaataggga tttggggtat ctttttactc tttaatatgt atatgccgac tatgagagcg
      121 gatgacgtag tttatgcaag tagattagat gaacttggct atttgggtgc ttcgatagaa
      181 cattataaga catggagttc aagaattatt atagaactat tcttaatgtt cttttctaaa
      241 cactttatgc tatggaaatt attaaattct acgattatgt taggaattgt agtattactt
      301 tgcaagtat
//
LOCUS       DACGEU010000255          309 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.264, whole genome shotgun sequence.
ACCESSION   DACGEU010000255 DACGEU010000000
VERSION     DACGEU010000255.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 309)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 309)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..309
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.264"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(33..>309)
                     /locus_tag="IXR40_002957"
     CDS             complement(33..>309)
                     /locus_tag="IXR40_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAQ4362716.1"
                     /translation="KWLFYLSRLIIQTALLKNLPETLDAQLRTKLQNLLTYEEGIYNA
                     MIYPYSNGKIEAKIPHIKTLKRLSYGFKSFENMKIRIFLINQLIQVK"
BASE COUNT           96 a           46 c           54 g          113 t
ORIGIN      
        1 gaaggactga ccttctgtct cagatttttt tgttatttca cttgaatcaa ttgattgatc
       61 aaaaaaatcc tgattttcat gttctcaaat gatttaaatc cataagataa tcgtttcagt
      121 gtcttgatat ggggaatctt ggcctctatt ttgccattag aatacgggta aatcatagca
      181 ttgtaaatac cttcttcata cgttaaaagg ttttgaagtt tcgtgcgaag ttgtgcatca
      241 agtgtttcag gaagattttt taataacgcc gtttgtataa ttaagcgaga caaataaaaa
      301 agccattta
//
LOCUS       DACGEU010000256          299 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.265, whole genome shotgun sequence.
ACCESSION   DACGEU010000256 DACGEU010000000
VERSION     DACGEU010000256.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 299)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 299)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..299
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.265"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            <1..>299
                     /locus_tag="IXR40_002958"
     CDS             <1..>299
                     /locus_tag="IXR40_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAQ4362717.1"
                     /translation="TIVGIHHKSAVITLVERLSKAIIALKPEGRKAVDIENSINEWLQ
                     SVPKNLFKSITFDCGKEFSNWKSISNTNDIDIYFADPGTPSQRGLNEHSNGLLRK"
BASE COUNT          102 a           63 c           54 g           80 t
ORIGIN      
        1 acgattgtcg gcatccacca taaaagtgcc gtcatcacac tcgttgagcg actttcaaaa
       61 gccattatcg ccttgaaacc agaaggccgt aaggcagttg atattgaaaa ttcgattaat
      121 gaatggcttc aatccgtacc caaaaatctt ttcaaatcaa ttacctttga ttgtggaaaa
      181 gaattctcta attggaaaag tattagtaat acgaatgata ttgatattta tttcgcagac
      241 ccaggaacgc cttcccaacg gggattaaat gaacattcaa acggactcct ccgaaaaga
//
LOCUS       DACGEU010000257          298 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.266, whole genome shotgun sequence.
ACCESSION   DACGEU010000257 DACGEU010000000
VERSION     DACGEU010000257.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 298)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 298)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..298
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.266"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            <1..>298
                     /locus_tag="IXR40_002959"
     rRNA            <1..>298
                     /locus_tag="IXR40_002959"
                     /product="23S ribosomal RNA"
BASE COUNT           81 a           54 c           91 g           72 t
ORIGIN      
        1 agacagttcg gtccctatcc gtcgcgggcg ttggaaattt gagaggagct gtccttagta
       61 cgagaggacc gggatggact taccgctggt gtaccagttg ttctgccaag ggcattgctg
      121 ggtagctatg tagggaaggg ataaacgctg aaagcatcta agtgtgaagc ccacctcaag
      181 atgagatttc ccatttcttt aagaaagtaa gatccctgag agatgatcag gtagataggt
      241 caggagtgga agtacagtga tgtatggagc ggactgatac taatcgatcg aggactta
//
LOCUS       DACGEU010000258          297 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.267, whole genome shotgun sequence.
ACCESSION   DACGEU010000258 DACGEU010000000
VERSION     DACGEU010000258.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 297)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 297)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..297
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.267"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
BASE COUNT          105 a           33 c           46 g          113 t
ORIGIN      
        1 gactacctgt attagtcctc ttttttgacc agattttgac cagtctattt tacattctaa
       61 tatattcata tgagctaatt ttatgattaa atggtaagtt tttccttgtt tgttttagtt
      121 taaactagtg tgtaattcaa aaatctatat ggaaggatct gtggggtaaa tcattataca
      181 aaagtaaaat tttacttatt aacaggctgt agaaatataa aaaagaacta aaatttaact
      241 aaattatgtg ctattcttaa ggaaagccaa gtgtatgaga aagtttctga gaatata
//
LOCUS       DACGEU010000259          296 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.269, whole genome shotgun sequence.
ACCESSION   DACGEU010000259 DACGEU010000000
VERSION     DACGEU010000259.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 296)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 296)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..296
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.269"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
BASE COUNT          105 a           52 c           43 g           96 t
ORIGIN      
        1 ctctataatt tctaggactg atggaaattt tctatctgtc ctagtttttt tgtaaaaaaa
       61 caaaaagaca tacaaaattt ccggtagaat agagtctcct acaacatcat tctgggggaa
      121 ttcttgtatg tccatgaatc attttatcaa acaactcttt actattaaag actcaaatat
      181 ccaaattcaa tcctttgaag aaacttttta taaaagcaga aaaagtatcg ttattgaggg
      241 aactctgatc cgtacctaca gacgttgtcc gtgttgtaaa gattctacaa agcaaa
//
LOCUS       DACGEU010000260          294 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.270, whole genome shotgun sequence.
ACCESSION   DACGEU010000260 DACGEU010000000
VERSION     DACGEU010000260.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..294
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.270"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            13..216
                     /locus_tag="IXR40_002960"
     CDS             13..216
                     /locus_tag="IXR40_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362718.1"
                     /translation="MVDKEVISEKVAEALLIPRYWTIETPLVEDAPTMLFEDLVKIAG
                     YELHYQENMETYENEYWLTKLEN"
BASE COUNT          116 a           43 c           59 g           76 t
ORIGIN      
        1 gtcgttcaaa ttttggtgga caaagaagtc atttctgaaa aagtagcaga agctttactt
       61 attccgcggt actggacgat agaaacccct ttagtagagg atgcaccgac tatgctattt
      121 gaagacctag tgaagattgc aggatatgaa ctgcattatc aagaaaacat ggaaacttat
      181 gaaaacgaat attggttaac caaattagag aactaaaaag gagaaaaaaa tatggctcaa
      241 aattactatg acgaatttgt caaattacct ttggataaaa tggcacaaaa aatg
//
LOCUS       DACGEU010000261          289 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.271, whole genome shotgun sequence.
ACCESSION   DACGEU010000261 DACGEU010000000
VERSION     DACGEU010000261.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 289)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 289)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..289
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.271"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            <1..187
                     /locus_tag="IXR40_002961"
     CDS             <1..187
                     /locus_tag="IXR40_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362719.1"
                     /translation="ELDELDTLSENPEKKHNLKKWLVERKAIHEIKKVLHEADKYEKY
                     DEKELDKEFKEINDLLL"
BASE COUNT          123 a           35 c           43 g           88 t
ORIGIN      
        1 agagttagac gaacttgata cgttatctga aaatccagaa aaaaaacata acctaaaaaa
       61 atggttagtt gaacgaaagg ctattcatga aattaaaaaa gttcttcatg aagctgataa
      121 atatgaaaaa tatgatgaaa aagaacttga taaagaattt aaagaaatca atgacttatt
      181 actataattg atttatacga ctcatttttg agtcgtcaga ctgcaaacaa cactctaaat
      241 ttaggagttt gtctacagtc tgaatagatt ttaaatttat tgtccataa
//
LOCUS       DACGEU010000262          288 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.272, whole genome shotgun sequence.
ACCESSION   DACGEU010000262 DACGEU010000000
VERSION     DACGEU010000262.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 288)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 288)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..288
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.272"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            <1..>288
                     /locus_tag="IXR40_002962"
     CDS             <1..>288
                     /locus_tag="IXR40_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAQ4362720.1"
                     /translation="NSTKKSYFYGLKIHMIVTKTGFPITYSITNPGVHDVKVLETLSE
                     EANLPNILGDKGYISHKIHEKLALKGITISVPPRKNMDKSEKLDHSLLGKQR"
BASE COUNT          106 a           58 c           48 g           76 t
ORIGIN      
        1 aactcaacaa aaaaatctta tttttatggt cttaaaattc atatgatcgt tactaagact
       61 ggctttccga ttacttactc aatcacgaat ccaggtgtcc atgacgtgaa agtgttagag
      121 actttatcgg aagaagcgaa tcttcccaat atcctagggg acaaaggata tattagccat
      181 aaaatccatg aaaagcttgc ccttaagggc attactatat ccgttccgcc acgtaaaaac
      241 atggataaat cagaaaaact agaccacagc ttacttggaa aacaaaga
//
LOCUS       DACGEU010000263          281 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.273, whole genome shotgun sequence.
ACCESSION   DACGEU010000263 DACGEU010000000
VERSION     DACGEU010000263.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 281)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 281)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..281
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.273"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            10..>281
                     /locus_tag="IXR40_002963"
     CDS             10..>281
                     /locus_tag="IXR40_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAQ4362721.1"
                     /translation="MQGVIAMMSKNNTNGRNQFAMLTIDDLVPQDHLVRKIDAALDFE
                     FIYPIVEATYSDLGRPSIDPVILIKLVFIQYLFGIRSMRQTIKEVDT"
BASE COUNT           84 a           53 c           56 g           88 t
ORIGIN      
        1 tgaaaacgaa tgcaaggagt gatagctatg atgtctaaaa acaatacgaa tggtagaaat
       61 caatttgcga tgcttacgat tgatgatcta gttcctcaag atcatctcgt tcgaaagatt
      121 gatgccgcgc ttgattttga atttatttat ccaatcgtcg aagccactta ctccgattta
      181 ggtcgcccaa gtatcgatcc agtgattctg atcaaattgg tgtttattca gtatttattc
      241 ggtatccgtt ccatgcgaca aaccattaag gaagtcgata c
//
LOCUS       DACGEU010000264          265 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.274, whole genome shotgun sequence.
ACCESSION   DACGEU010000264 DACGEU010000000
VERSION     DACGEU010000264.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 265)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 265)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..265
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.274"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            <1..>265
                     /locus_tag="IXR40_002964"
     CDS             <1..>265
                     /locus_tag="IXR40_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362722.1"
                     /translation="SAKVRFDEGTTGAIDKLRLVYRTSPGEKILLEANSTNITTDDVG
                     KEITIKGTANVNYQITNLDRFYMSISFVDRDKINGGFKLYDIK"
BASE COUNT          105 a           30 c           55 g           75 t
ORIGIN      
        1 tgagtgcgaa agttcgattt gatgaaggaa ctacaggagc tattgataaa ttacgtttgg
       61 tgtatcgtac atcaccagga gaaaagatat tattggaagc aaatagtaca aatattacaa
      121 cagatgatgt agggaaagaa ataacaatca aaggtacagc taacgttaat tatcaaatca
      181 caaatttaga tcgattttat atgagtatta gctttgttga cagggataaa ataaatggcg
      241 gatttaagtt gtacgacatc aaaat
//
LOCUS       DACGEU010000265          233 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.277, whole genome shotgun sequence.
ACCESSION   DACGEU010000265 DACGEU010000000
VERSION     DACGEU010000265.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 233)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 233)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..233
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.277"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
BASE COUNT           79 a           35 c           45 g           74 t
ORIGIN      
        1 tgagaaaaag catggaatgc gctgcatcag gtatcgaggc ttagaaaaaa atcaggtgca
       61 tacgatgctt gtttttgccg aaatgagtct gaaaaaattg gtcacttagc agtgggagca
      121 tatgtcttca tattttttat tatacaaaaa tagacaaaag tatcagtcta cactcttagt
      181 aaagaggaaa ctgatacttt tgtctacagt atgatatttc ttacatctac ttt
//
LOCUS       DACGEU010000266          231 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.278, whole genome shotgun sequence.
ACCESSION   DACGEU010000266 DACGEU010000000
VERSION     DACGEU010000266.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 231)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 231)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..231
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.278"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            <1..201
                     /locus_tag="IXR40_002965"
     CDS             <1..201
                     /locus_tag="IXR40_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010868911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HAQ4362723.1"
                     /translation="YLNNLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTR
                     KEGTLFGFSVCTEIKVLLGIPA"
BASE COUNT           77 a           45 c           45 g           64 t
ORIGIN      
        1 tacctgaata atttgattga acaagaccat cgtccagtaa agagacgcaa taaattctat
       61 cgaagtttac gcactgcctc taccacgatt aaaggcatgg aagccattcg aggattatat
      121 aagaaaaccc gaaaagaagg cactctcttc gggttttcgg tctgtactga aatcaaggta
      181 ttattgggaa tcccagctta aatcatagat accgtaaggg attttattct t
//
LOCUS       DACGEU010000267          224 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.279, whole genome shotgun sequence.
ACCESSION   DACGEU010000267 DACGEU010000000
VERSION     DACGEU010000267.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 224)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 224)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..224
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.279"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..137)
                     /locus_tag="IXR40_002966"
     CDS             complement(<1..137)
                     /locus_tag="IXR40_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase domain-containing protein"
                     /protein_id="HAQ4362724.1"
                     /translation="MPSTFNVTNIPMKIAFAWGGIIVLYEVFIKKNFFKMRFSWLLIG
                     A"
BASE COUNT           92 a           43 c           22 g           67 t
ORIGIN      
        1 attgctccaa tcagtagcca agaaaaacgc attttaaaaa aatttttctt tataaaaacc
       61 tcatacaaaa ctataattcc accccaagca aaagctattt tcatcgggat attagttaca
      121 ttaaaagtac taggcataaa ataaagcaga caaatgatta aatttattac tcgaaacgca
      181 tctcgactta ataaactctt ctctaaaaca ggtactattc tatt
//
LOCUS       DACGEU010000268          224 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.280, whole genome shotgun sequence.
ACCESSION   DACGEU010000268 DACGEU010000000
VERSION     DACGEU010000268.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 224)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 224)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..224
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.280"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            <1..>224
                     /locus_tag="IXR40_002967"
     CDS             <1..>224
                     /locus_tag="IXR40_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HAQ4362725.1"
                     /translation="PSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHEDNEGDSGVAA
                     ESQTPAKPAAEPTVDTESAGSSSEGVFQFK"
BASE COUNT           70 a           47 c           58 g           49 t
ORIGIN      
        1 ccgtcacctg ttacaggaac ggttaaaaat gtgattgttc cagaaggtac cgtagcaaat
       61 gttggggatg tattagtaga aatcgatgca ccaggacacg aagacaatga aggggacagt
      121 ggtgtagccg cagaatccca aactccagct aaaccggctg ctgaacccac tgttgataca
      181 gaatcagctg gatcgtcaag cgaaggagtc ttccaattta agtt
//
LOCUS       DACGEU010000269          222 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.denovo.281, whole genome shotgun sequence.
ACCESSION   DACGEU010000269 DACGEU010000000
VERSION     DACGEU010000269.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 222)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 222)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..222
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.denovo.281"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            <1..>222
                     /locus_tag="IXR40_002968"
     CDS             <1..>222
                     /locus_tag="IXR40_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAQ4362726.1"
                     /translation="SFIAKNCQVSLTTVIRTLKEFKSYLPKQSKRILPRVLMVDEFRS
                     HASIEDKMSFICADGETGQLIDVLPTRKL"
BASE COUNT           67 a           40 c           45 g           70 t
ORIGIN      
        1 tatcttttat tgcgaaaaat tgtcaggtat ctttgaccac cgttattcgt acgttgaaag
       61 agtttaaaag ctacttacca aagcaatcta agaggattct ccccagagta ttgatggttg
      121 atgaatttcg ttcgcacgct tccatagaag ataaaatgag ctttatttgc gcagatggcg
      181 aaacaggaca attaattgat gtcttgccta cgcgtaaatt gc
//
LOCUS       DACGEU010000270        12927 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.guided.076, whole genome shotgun sequence.
ACCESSION   DACGEU010000270 DACGEU010000000
VERSION     DACGEU010000270.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12927)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12927)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12927
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.guided.076"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..1876)
                     /locus_tag="IXR40_002969"
     CDS             complement(<1..1876)
                     /locus_tag="IXR40_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4362727.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAAARPAQTNTVVKTETFAGETIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVEEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     G"
     gene            complement(1873..2745)
                     /locus_tag="IXR40_002970"
     CDS             complement(1873..2745)
                     /locus_tag="IXR40_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAQ4362728.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            complement(3087..3959)
                     /locus_tag="IXR40_002971"
     CDS             complement(3087..3959)
                     /locus_tag="IXR40_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAQ4362729.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            4087..4656
                     /locus_tag="IXR40_002972"
     CDS             4087..4656
                     /locus_tag="IXR40_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HAQ4362730.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLLVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            4723..5460
                     /locus_tag="IXR40_002973"
     CDS             4723..5460
                     /locus_tag="IXR40_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAQ4362731.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            5691..6959
                     /locus_tag="IXR40_002974"
     CDS             5691..6959
                     /locus_tag="IXR40_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosaminidase"
                     /protein_id="HAQ4362732.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            7446..7910
                     /locus_tag="IXR40_002975"
     CDS             7446..7910
                     /locus_tag="IXR40_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAQ4362733.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            7894..8523
                     /locus_tag="IXR40_002976"
     CDS             7894..8523
                     /locus_tag="IXR40_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HAQ4362734.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGVEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            8877..10355
                     /gene="msr"
                     /locus_tag="IXR40_002977"
     CDS             8877..10355
                     /gene="msr"
                     /locus_tag="IXR40_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Msr family ABC-F type ribosomal protection
                     protein"
                     /protein_id="HAQ4362735.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            10402..10848
                     /locus_tag="IXR40_002978"
     CDS             10402..10848
                     /locus_tag="IXR40_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HAQ4362736.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(11047..11562)
                     /locus_tag="IXR40_002979"
     CDS             complement(11047..11562)
                     /locus_tag="IXR40_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAQ4362737.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            11679..12881
                     /locus_tag="IXR40_002980"
     CDS             11679..12881
                     /locus_tag="IXR40_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAQ4362738.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
BASE COUNT         4030 a         2380 c         2641 g         3876 t
ORIGIN      
        1 cgccatttgt gaatacaacg accatatccg tgtttttgcc tgcagattga atagcggcaa
       61 gatcaactaa agcaatcaat tgacctcttg cgactttttg accttcttct acatataaag
      121 tgaatggttc gccttttaag tcaacagtgt tgatgcccat atgaagcaag acttcgatac
      181 cagcatctgt ttggattccg acagcatgtt tcgttgggaa aatgtttgtg atcgtaccag
      241 cgattggaga gaagatttct ccattttctg gtaatacagc atagccgtca cccatcattt
      301 tttccgcgaa tacatcatct gaaacttcag tgattggaat cagtttccca tttgcgatag
      361 cgtaaatatc ttgttcgatc gtttcaccgg caaatgtttc tgttttaacc acggtgtttg
      421 tttgtgcagg tcgtgctgca gcaccaccat gtagttttgc catctcatct gcaacgaatt
      481 gtacttctgt acctacgatg acttgcgcat tttttccgtc gatgatcttc ataccaggta
      541 cgccagtggc tttgatttta ttttgatcga tcaggcctgt atctttgact tgcaaacgaa
      601 ggcgtgtagt acagttatcg atcgaagtta cattgtcggc tccgcctaat gcagcgtaga
      661 ttttgcttgc ttgtgccgca tatttattgt ctgaattagt cgttgcagta tcgtcatctg
      721 aaagatctgc ttcctcgcgg ccaggagtca tcagatggaa ttttttgata gcaaagttaa
      781 agccaaagta gtaaatcact gctgttacta atccttggac gatcaacatc aatggctgat
      841 tcgcaatcgg atttttcaaa gataggaagt aatcgacaaa tccggcacta aaggcaaatc
      901 ctgctgtcca atggaagaat gcactcactg ctaaagaaat cccagtgaaa attgcatgca
      961 agacatataa tggccaagca acgaacataa atgaaaattc aagtggttct gtcacaccag
     1021 taaagaatga agcaaaagct gctgctagca tcaaggaagc tgtttttgct ttgttttctg
     1081 gacgtgcatt tctgtaaata gcatatgctc ctgctggaag cccgaacatc atgattggga
     1141 aaaatccagc ttgatacatt cctgttacgc cttttgttcc ttcagaagcc aaaaatttac
     1201 caatatcatt gattcctgct acgtcaaacc agaacacgga gttcattgct tgatgcaatc
     1261 ctgtagggat cagtaaacgg ttgaagaagc cataaagacc tgcaccaccc cagcctaaac
     1321 tcaaaatgaa tttagcaaaa gaaactaaag cagagtaaac cggaggccat acgagcagta
     1381 gcactgcact gatcagcaac atgacaaagg cagccaagat tggcactaga cgcttgccgc
     1441 taaagaaaga taaagccatc ggtaattttg cttcgtggaa acgattataa agagctgccg
     1501 caatcaatcc ggcaataata ccaataaata cgttactgat ctgagcaaaa gatggatcaa
     1561 ctgattctgg tttgatattc aataaagtag ctactgaatc agtttttaaa acatttactg
     1621 gaacttcaaa tgcgaccaaa cctgccaagg cagcagcacc tgatttgtcc actgacatcc
     1681 ctagtgctaa cccaacggca aacagcaaag gtaattgacc taaaactgcg ttaccgccag
     1741 cttgtaaaaa atgagcgaca atgtcgttac tataagatgc ccaccagttt ccgatcccta
     1801 ctagtaaagc agcagcaggt aagaccgcaa ctggaagttg aagggaacgt cccattcgtt
     1861 gtagatatgc tttcaatttt tttcctcctc atgattgtta acatttgttt gtacgattgc
     1921 gcttcttaaa cgctcgatat ggatggccaa gtaacccagt tcttctttcg tgatcgcgag
     1981 ctggtattct ttggtcagca acacacggat ttttttagaa atcttatagc tttctgggta
     2041 ttttcgtttg accatttcta cgatttccgt gtctaaaaca gcatattgtt gcgcatgggt
     2101 tcgttgtaga agcagtcgta aatgattcac cagtcttgaa taattcagtg aaaatggttc
     2161 tgaatggata tctgtttcca attctgattc cactaaatgg atgatgtcag atacaatcgt
     2221 cacttcacgg atactgcgat ggttattgtt ccgaccgctt cgtccgctgt gaatatggat
     2281 tgcgatatat cctgcttcgt cataagtata tggaatccca agctcttttg tcagatactc
     2341 tactgcccat tgagcaatac tgaattcatc actgtaaagc acttcgattt ctcttaaaag
     2401 tttgttgcgg atgacgatac cgttattaat gttctccgca gaaaaagcaa tgtggtcggt
     2461 caaagcgatc aatacatgtt cattcaactt ttccatcaaa acagtttccg catgatcaat
     2521 gatcgtttct gctgcaaata aaaagcgttc atcaatctga ttaagtaaat tttgcaactt
     2581 gatttgacct tctggttcca tgacaaatat ccgttcgaca tcacgatcaa aaatcaaatc
     2641 atttcttttt ctgtcaaatc caatcccttt tccaatagct actttttcct gtccaccgtc
     2701 atctaccaat actgcatttt gattaaagat ctttttgatt ttcatgcgcg cacccttttt
     2761 gaagatttgg ttttcacgtt tgctagacca gttgattgcg gccaaacaaa aatagacacg
     2821 aaaaacctcc tagggaaacc atgttcctca gagatttttc atgcctagta tgatctagtc
     2881 acatgaaacg aattattgtt aacgtaatca attttatata gacagttatg ttttgtcaat
     2941 tcttttttta taattatagt aatttactgg aattatcaga aataaaagga agaaataaat
     3001 taagaaactt atgttattta atcgttggat cttttgctta tcttattcgt tgttaaaaag
     3061 ctgaaagcga aggaaaaaaa ctctacttaa ctgtatttct ccgttaggac atctaaaaat
     3121 ttacgagcag caggagaaag aggctggtct tttttccaaa tgagattcag tgaagcttgt
     3181 aatggcggat cgagtgggat gaatattttt tccgtcccat aagtattgat gatcccatct
     3241 agagctaatg caccaaaagt cccgttatcg accatcaaag aagcattgta caataagtta
     3301 tatgttccga cgatcgataa ctgatctatg ctgaaaccta gccattcagc tagttgactg
     3361 tccactgacg tttgccggga aatgatcaaa ggaacagttt tcagttcctg cggatggatg
     3421 acggtttgct ttgctaaagg atgatttcga tgtatcaaaa gtccccaacg atcttgggct
     3481 ggcagtcgaa atgactggta tttttgtttg tttgtcggtt cgattacgag tccaaaatca
     3541 agtaatccgc tatccagttt gtctatgata tcatctgcat tcccgctata taaatgaaac
     3601 tggatatcag gatgcgcctt gatcaacgaa tgaaggctat cagaaatgaa agagattgct
     3661 ttagtttcgc ctccgccaat gtagatttct ccagagatga ttgcgtcatt tgttaaattg
     3721 ttcgccgttt tttctaccaa cgacaagatt tcttttcctt ttgaataaag atatcgacca
     3781 gaatccgtca actgtatctc tcgggagccc cgagtgaaaa gtgtcacacc aagttcttct
     3841 tctaaatctt tcagttgttt tgagagagta ggttgcgtga tatgcagaga ttttgctgct
     3901 cggctgatat ttttttctct agctactgct aaaaaatacg tcagtatacg aatatccatt
     3961 ttttccctcc tgtttttaaa aaagcatacc actaagtata gttaaaagga atagttaagt
     4021 atgttttata agtattagac atgataagcc gtccgttata aagtaaggat aaaaggaggg
     4081 agcaaaatga caagcctcat cgaaaaacaa atcgtcaata aagagattcg agtaacggat
     4141 ccgctctttg aagtgatcca tcagatccaa gctgaaaacg aagagccttt agcagcgctg
     4201 aatactgggt accatgaacc agcagatatc cgcaaacggc tagaaaatat cattagtgac
     4261 aaagtagatg atacggtgac tgttctgctg cctttttata cagatttcgg caaacatatt
     4321 agtataggga aaaatgtctt tatcaatcgt caagtgatgt tcgttgactt aggtggcatc
     4381 tgtttagaag attcagtatt gattggtcct cgtgtcaacc tcatcacggt gaaccatcta
     4441 accgatccaa aagaacgaag aggcttgtta gtaaagccaa tccacatcaa gaaaaatgct
     4501 tggatcggag caggagcaac tattctgcca ggcgtaacga ttggcgagaa tgccattgtt
     4561 gcagcgaatg caactgttac gaaagatgtc ccagacaata ccatcgttgc aggaatccct
     4621 gccaaaatcg tcaaacctgt cgaacggatt atttgaacag taagatgaaa taagagatag
     4681 tgagtataag caagagattt ttcaaaacag gaggagaata gaatgaatga tttatcagaa
     4741 aaagtgattg tcatcatggg cgcttcaagc ggaatcggtg aagcaacaac gaagctatta
     4801 gcagaaaaag gggctaaact agttatagct gcacgccgag aagatcgcct aaaagcaata
     4861 aaagaatctt taccagaagc tgagctatat attcaaacag cagatgtaag agattttgca
     4921 caagtccaag cagttatcga tttagcgatg gaaaagttcg gtcgaatcga tgtattgtac
     4981 aataatgcag gaatcatgcc aaccgctcca ttagttgaag gtcaccgtga tgaatggcaa
     5041 aatatgcttg atatcaacat catgggtgtg ttaaatggaa tttccgccgt acttccaatc
     5101 atggaaaaac aaaaatctgg gcatatcatt tcaactgatt ctgtggcggg acatgttgtt
     5161 tatcctgatt ccgccgttta ttgcggaaca aaatttgctg tccgtgcaat catggaagga
     5221 ttacgtcaag agcaacggca aaataacatc aaatctacga tcatctctcc aggagctgtt
     5281 caaactgaat tatatcaaac catcagcgac aaaaaggctg ctcttgaact tcatgaagcg
     5341 caaaaagaat ggggattgac ctccgaagat atagcttctg ctgtagcatt tgcgatagaa
     5401 acgccagacc ggatgtctgt cagtaacatg attatccgtc cgacgacaca ggaagtataa
     5461 tccataacgg ataatatcca aagagaatta cttgttaaat agttattcaa acgaccatca
     5521 atttaaggcg tgaatggaga agaatattct tcatttacgt ctttttatgt agaaaaagca
     5581 aatttatcaa aaagaaacaa atgttattta aatatggaca ttgacttgct tttacttttt
     5641 tagttacact gttatttagg aaaagtttca taattcaaag gagaaaaaag atgaaagcaa
     5701 agaatttatt atttagcgtt attcttttag gaaatctagc agttgccaac acaacagtgc
     5761 tagctgaaga atcgacagaa actgtcgcaa ctcagacatc gagttcttca gaaacaggaa
     5821 ttgaaaacga tacagagagt actttgcagt cagctactgt ctcagaaaat acaatttcaa
     5881 ccgaagaacc aacaactgaa acaacagaac aaacacaaac cgaagacagt acatcagcag
     5941 aagctcagaa caatccagag aatgcagaag aaatcacgaa ccaattgaca gatgggcaaa
     6001 cattgacaca tacccatcaa gcagatttgt ctgaattcga aaactatact ggctatgctt
     6061 tttatgctcg ctcatctgct aattctcaac aagcgttcat tgatagtatt gcctcaactg
     6121 cacaaagttt ggcaagtgcc aatgacttat atgcatcagt catgattgct caagccatcg
     6181 ttgaaagtgg ctgggggaac agtactttgg cttctgcccc taattacaat ctatttggga
     6241 ttaaaggaag ctataatggc caatctgtta cgatgcctac ttcggaatat gtgaatgggc
     6301 aatggattac ggtgaatgcc gcttttagaa aatatccttc gtacaaagaa tcattgcaag
     6361 ataacgtaac ggtattgaag acgacttctt ttcagccagg cgtttactac tattccggtg
     6421 catggaaaag caatacgaac tcttacaaag atgctacggc ttggctaaca ggtcgttatg
     6481 ccactgcgcc taattatggt tctacattga acaatgtaat cgaaacctat aatctgacac
     6541 agtatgatac agcaccaact tcaacttctc cgatgtatcg tctgtataac cgtcatacag
     6601 gagaacattt atatacattg aatgccggag aaaaaaatta tctgccaact gtaggctggg
     6661 aatatgaagg gattgcttgg caagcaccaa acagcggaca acctgtctac cgtttataca
     6721 atccttacag tggagaccat cattacacaa tggcacaatc tgagatcaac tctttaacaa
     6781 aaatcggttg gcgttatgaa ggtctaagtt tttattctgg tggttccaag ccaatttatc
     6841 gactatttaa tccaaatgaa aaaactggta cccatcacta taccttgagt gctaaggaaa
     6901 gagattggct aacaccgatg ggctggagat atgaaggaat aggattttat ggttattaaa
     6961 aagaggtagt gaaaaagctg ccctgcatca agtagtaaga acagccaaac aaaaacagat
     7021 tttcatgttt tttgtttggt tgaacttatt accgcagatg caagtttttg aacaccgttt
     7081 actcaaaaaa ggttgtgaca acatcttgtc ataacttttt tattactgtt taagcatact
     7141 gatccaattt ctaatattcg acgggattct tgcaaaaggc gatttcggaa atttttggcg
     7201 gtgtaaaatt ttctactgca gaagagctat cttctatagt ttgataagaa tcaataatct
     7261 tggttttagc gttgtgcttt ctttatcatt ttttccgttc attctacaaa aaatttcttt
     7321 tctctatact tttctattga gagcgttttt tttattacac agctgattct ttgacttttt
     7381 tcttttttta ttctattatt gacaagtcaa tcgttgacga gtcaattatt agaaaggagg
     7441 aaattatgtc tttagaagag attagtcacc ttttatatca aatcaaatta gccgatcaaa
     7501 aaatcgtcca gatctttgaa gaaaatatcg gtataagtct tactagatac gagatcatga
     7561 tgagactgaa agaagaaaat ccattgctac aaagcagttt gcaagaaaag ttgcagattg
     7621 atcaaggagc agttactcgt catctgaagg tattggaagc aaatggctat gtttcgcgtc
     7681 agagaaatcc tcagaacaac cgggaagtgt atgtagcgct aacagaaaaa gcccagaaga
     7741 aaatcgagca ttgtgaaatg gaccataaag atacaggttc cgtgctatcc ccggctttca
     7801 gcgatgtaga aatgaaacaa tttctaacac ttttagataa attgaatacc caactttgca
     7861 atataacaac agaaacgaaa gaggttaata ataatggaac aaaaaaatga tttttcaaca
     7921 attatgactg gtagaagatc cgttcgcgta tatgatgaaa catacaaaat cccacacgaa
     7981 gaaatgctgg aaatgatcaa agaagcgacg actgcacctt cttctgtcaa tatgcaacca
     8041 tggcgctttg tggtcgctga aagcgaggaa gcaaaagaaa tcttgcgtcc tttgatccgt
     8101 ttcaatacga gacaaaatga tacttcttct gcaatggtca tgatttttgg cgatatgcaa
     8161 tgttacgaat atggcgaaga aatctataac caagcttacg aatcagggaa gatgccaaaa
     8221 gaagtcagag atcaacaatt agctgcgatc attccttatt acaagagttt ttcaagagaa
     8281 gaaatgaacg atgtagtcaa agtcgattct agcttagcgg ctatgcaatt catgttagtt
     8341 gcgcgtgatc atggctatga aacaaatcca attggtggag tcgaagcaga tcagttggca
     8401 gaggcatttg gtttggataa agaccgttat gttccagtta ttattttatc aataggaaaa
     8461 gcggtagaag aaggttacga gtctgttcgt ttagcaccag aaaagatcac tacgttcgaa
     8521 taaaaggttt tcagttacta ttcagtagct attgcttttt ttgaatcgtg tgtggtaacc
     8581 taataaaaaa ggaggtcgga aaaatgactg catcgatgaa attacgtttc gaacttttga
     8641 ataacaacta aataaattca aaagacatgt ataaacaaca atttcatgga tggagtatgt
     8701 ccattttttc gaacgacagt agaataggtg aaagctatga cagatttggt gatttagtca
     8761 tagttatttc gttcagagta ggaaaagatg tgatgcagtt tttttgcaaa cagatttttc
     8821 tgctcttttt tagtatcgat aattgttgtt ttacatgaaa taggagtgta aaacatatgg
     8881 aaaatttagc agtaaatata acaaatctac aagtcagctt tggcaaccag ctagaactat
     8941 ctattgattc tcttcgtgtc tatcagcaag atcgtatagg gatcatagga gaaaatggtg
     9001 tcggtaaatc gactttgctc aaactaatag ccggtgaact ttttcccgat catgggaaaa
     9061 tccaaacaga gatcaccttc aactacctgc ctcaattaac ctatctcgct gaagcaaagg
     9121 acctaaattt ggaattagcc agtcatttcc agttaagact ggaagaaact tcagagcgga
     9181 aatggagcgg aggggaagaa cgaaagatcg agttgatacg tcttctttct tcttatgaac
     9241 aagggatgct tctagacgag ccaacaaccc atctagatag aaaaagtatt gatcgactga
     9301 ttgaagagct tcgttattat tatggtacgc tggtttttgt tagtcatgat cgctattttc
     9361 tagatgagct agcatcgaaa atctgggaag taaaagacgg agaaatccga gagttttcgg
     9421 ggaattatag tgcctatctc actcaaaagg aattggagaa aaagactcag ctacgagaag
     9481 cagagtcgat catgaaagag aaaaaacgat tggaaaaatc gatccaagaa aagaaaaaac
     9541 aagcggaaaa gttggaaaaa gtgtccagta aaaagaaaaa gcaacaaatc agaccggatc
     9601 ggttgtcttc ctctaaacaa aaagacagtg tacaaaaagc catccaaaag aatgcgaaaa
     9661 cattagagag aagactccaa aaaataggag aaacaaccaa gccgcagcag atgaaacaaa
     9721 tccgttttcc agtaccaaaa tctcttgaac tccacagccg ctatcccatc atgggacaaa
     9781 atgtccaatt ggaaagaagt gggagaacat tactggtaaa tggtgatttt cagttttctt
     9841 taggtaaaaa aatcgcgatt gtcggtgaaa atggttcagg taagacaacc ttattagaac
     9901 atatccgcaa acaaggagaa ggaatccttc tctctccgaa agtaagcttt caagtatatc
     9961 agcaaaaggg ttatcaaatg acatctgaag aatccatcat tcgttttgtc atgagacaaa
    10021 cagagttttc agaatcgctt gtccgtagtt tgctgaatca cttagggttt gctcaggaaa
    10081 ctttgacgaa accgttatgt acattaagtg ggggagaagc gacccgtctg acgattgctt
    10141 tgctttttac taagccaagt aatgtgttgc tgttagatga accgactaat tttattgata
    10201 tggcaacgat cgaagcttta gagaagctaa tgcaaatata tccgggaacg attttgttta
    10261 cttctcatga ttcttacttt gtcgagcgta cggctgatga agtttatgaa ataaaagggc
    10321 agaaaataaa aaaagtactt acgagaaatt tttaaatgtg ctacgatgat tttcgtgaca
    10381 aatttaaagg agtggtacag attgcctaca aataaaaaag aaggaataat ttttacaaca
    10441 atgatgtgtt ttttgatggt cttggggatg agcgcgtata atttatggct gcatcaagat
    10501 cttcatttat caagtttgtt gattggtcta gtgcctggat tcgtggtggc tttcattttg
    10561 gatgtcttca tcatcggtgt gctggcgaaa aaaattgcct ttaaactacc agtaaatcca
    10621 gaaagcaagg tccaaatgat cttaactatt tcatgcttga tggttttagg aatggtgaca
    10681 tgtatgtctt tattcggtgt gatcatggaa caaggaatac ctgatcaatt attctctgct
    10741 tatatgaatg cttggaaaat gaatgtgatt gccgctttac cgttgcagtt gatcatcgtt
    10801 ggcccgcttt caagaagtgt gctaaaagca attcaaagta atgaatgatg gaacactgtt
    10861 atttgaaaaa aggccttggc atgctttttg tcatagtctc ttgaatgcag ttctagaaaa
    10921 atagtgatcc gaacgatagg ttttggcctg tcgttcggat cgctttttct tttccaactg
    10981 tattgctctt ttattgaaga taatttgctc ttcaatagat atttctagaa aggttctgtt
    11041 tatcccttac tcaaaaaact gctgcatttg ttctcttact tgctgacacc attggagttc
    11101 ctgctgacaa agcataattc tgcgctggat cacaacataa cgtccaaatt cttgtttctt
    11161 gtctagcgag aggtcattca attttttttg atttttttgc atgattttgt tcagctgttg
    11221 ttctctagtg aatagcagtc cagtagctgt tgttttatcg agcgtcgaaa aagcatagat
    11281 ttttgctaga aattcatctt tttgcgtagg agcgggagtt tcctctttga tccattcctc
    11341 tacaagagca cgtccttcat cagtcaagtg gtagatcttt ttttgagagt gctcgtcttt
    11401 gtccaaaacg gtcacataac cctgctggtc taacttggca agcgttgtat agatctgact
    11461 gtgatgggct tcccaaaaaa ttgtgatcag ctgcttcaat tcatacccag aacgtggttt
    11521 ggataaaagc acgcataata atatataggc taaagtattc ataaaaatcc tacctctcgt
    11581 cttattttct ttattatatc acagtaaagt ttccacgttt tacatgtgca tatttacatg
    11641 taaaataaat catgtatgat gctaatagag agaaagggat ggaaatattg gagaatcaaa
    11701 tagatataca agaacaaaca aatgaagaaa caaaggggaa aagttcagcg ctagttgtag
    11761 cagctacctg tatgatcgct tttatgggag tgggtctagt agacccaatc ttaaaaacga
    11821 ttgctgcaca gttaaacgct acgccagctg aaacgaccct gttatttact agttacatgt
    11881 tagtcactgg tgtggtgatg ctatttacag gtttcttatc tagtcggatc ggtttgaaaa
    11941 aaacattgat gacaggattg tttatcatcg ttgtattcgc tggtcttggc ggattatctg
    12001 ggaatatcgg aatgctgatt gggttacgtg ccggctgggg tgtcgggaat gctttatttg
    12061 tctctactgc tttagcaacg atcgtcagta ttttagttgg taacacagaa aaagcaatca
    12121 tgatgtatga agcagcactt ggctgcggaa tggctgttgg ccctctagtc ggtggggtct
    12181 tgggcagtgg ttcatggcgt tatccatttt ttggggtagc atttttgatg ttttgcggtt
    12241 ttatagccct agcggtactt ttacctgaaa ctgagaaacc aaagagaaaa gtaggccttt
    12301 gggaaggtgt caaagcgtta agcaatcata aacttcgttc agttggacta atcgcattgt
    12361 tatataattt cggattcttt actttacttg cgtatgcgcc atttttattg attggctatt
    12421 ctgaattaga agtcggtttt gtattttttg gctggggtgt gcttctggct attgcttcga
    12481 ttttcgttgc accggctctt gagcggaagt ttacgactta tcggacaatt ttagcagcat
    12541 ttgtcttatt cattatttgt ttgctgttat taggagctgg aacttctatg ccagtccttg
    12601 taccgatcag cattgtgtta gcaggatttt tccaaggaat tatcaataca ctgttgacga
    12661 cgattgctat ggaaatacca ggtctgcaac gaaacgttgc ttcgtccagc tatagttttg
    12721 tccgcttttt cggtggagct ttagcaccat ttattgcagg tgtgattggt gaacatattg
    12781 gtgaaagcta tgcgttttat tttgcaggtg ccattgttct tatcagtgta tgttgtatca
    12841 tttatcaccg taattatttt gctacaaatg aagaagaata agaaatcaga ggttgtgaaa
    12901 aagctgtcct gcatcaagtc ataagaa
//
LOCUS       DACGEU010000271        10473 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.guided.094, whole genome shotgun sequence.
ACCESSION   DACGEU010000271 DACGEU010000000
VERSION     DACGEU010000271.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10473)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10473)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10473
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.guided.094"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            86..982
                     /locus_tag="IXR40_002981"
     CDS             86..982
                     /locus_tag="IXR40_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HAQ4362739.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            complement(1132..2073)
                     /locus_tag="IXR40_002982"
     CDS             complement(1132..2073)
                     /locus_tag="IXR40_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HAQ4362740.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            2199..3320
                     /locus_tag="IXR40_002983"
     CDS             2199..3320
                     /locus_tag="IXR40_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HAQ4362741.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            3578..5080
                     /locus_tag="IXR40_002984"
     CDS             3578..5080
                     /locus_tag="IXR40_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HAQ4362742.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            5147..5656
                     /locus_tag="IXR40_002985"
     CDS             5147..5656
                     /locus_tag="IXR40_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAQ4362743.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNT"
     gene            5885..6946
                     /locus_tag="IXR40_002986"
     CDS             5885..6946
                     /locus_tag="IXR40_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HAQ4362744.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            6949..7845
                     /gene="murQ"
                     /locus_tag="IXR40_002987"
     CDS             6949..7845
                     /gene="murQ"
                     /locus_tag="IXR40_002987"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HAQ4362745.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            7859..9841
                     /locus_tag="IXR40_002988"
     CDS             7859..9841
                     /locus_tag="IXR40_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAQ4362746.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(9906..10352)
                     /gene="nrdI"
                     /locus_tag="IXR40_002989"
     CDS             complement(9906..10352)
                     /gene="nrdI"
                     /locus_tag="IXR40_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HAQ4362747.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
BASE COUNT         3416 a         1850 c         2273 g         2934 t
ORIGIN      
        1 caaatatagg aaacgtttta ctggcttttt actatttaaa caggctatca taggaaaaag
       61 tgacagagaa agtgaggcgg aaaagatgaa caaaaatgac gtactgctag ttgcaaaaaa
      121 taaatcactt tattttttgc cttccatccg ctctttagat gtttggtccg gaaaagattt
      181 actacagtcg gaattcatta aatcagctag acaacagttg gcaaattatc agctgatcgt
      241 ttttttagat tatggatttg atatggagat ggctcgacgc gtgcgcccat ttaccaatgc
      301 aaaaattgtg ttattttttt ggaatcactt caaagcagaa cacgaggcga tgctgaagca
      361 ggcacaagat gaaccggcaa tcgatgagat ttatcatttt gattttttgg aagcaaaaga
      421 acttgggctg aaacataata gttcatttta ttcgaaacat atgaattttt cttctagcga
      481 accaaagacg gatctatttt ttggtgcaac gaataatggg agaaaagaac gagcagaaag
      541 ctataagcag gaatttataa aaagagatgt tacgaccaac tatttcattc ttccacatcg
      601 agggaatgaa caacctggat atcttactta tgaagagtac ctgaaaaaaa caggggaatc
      661 gcgcgggatt ctggaactgt tgcgggaggg tcagcaagga gtgactttgc ggacatttga
      721 atccatgtat tttcaaaaga aactagtgac ggataatcaa gcgattgctc attatcattt
      781 ttatcgtcct gaaaatattt ttttgcttcg agaacgtgat ttagatgaat taccggaatt
      841 tctgcataca ccatttaagc caatcctatc agagctattg gaattttatg atgcagaaaa
      901 ttgggcaaaa cgatttatca ctaacgattc cactatttat gagcaatacg aatatgacct
      961 ctcctctgtt gaaaacaaat aaaaaaccta cattttgaag agattatgta ctgaaacaaa
     1021 caagcacaat tcttatggca tcatgagagt tgtgttttct ttttgatctt ttattgggct
     1081 taaaaaaaga gaaccagctg ctgattcagc tgattctcat cagagagcct tttattctgc
     1141 gccaaggatt ccttcttttg catggactaa ttgggtcaaa aaggcacaat atggtgtagc
     1201 aatatcatat ttttgtcctt ttcgccaaat ggcaccattg atgtagtcga tttcagtcaa
     1261 acgatggttt ttgatcaggt cttggtacat agatgggtaa tgcaacccga tgttgtcagg
     1321 atcataagta gaagcaatat gttggtacac ttcttcttga tctagtatga ttccttcttt
     1381 tgctgcgata gaagcaaatt cagatacgat tgttcgaacc atgctctctg ccgctttttg
     1441 cgcgcctagt tcagcaatat tacaatccaa aatcgtgcat aaaccattca atgttccatt
     1501 tacacaagct tttcgccaaa tggaataacg aacgttatgg ctatagatcg gatttaaatt
     1561 tgcttcttga aagacttcta caactttttt tgtaaatgct tcgccttctg gttccaagtt
     1621 ctctagttcg atttctccat cacctaacaa tgtgactttt ccgggaccag ctagaccagc
     1681 tgtccacatc gtgatcccaa ataagatatt tttctttggc acatattttt ccagtacatc
     1741 ttcatgacct aatccattta gtaaacacaa aacataagta ttgtcagtaa taatggattg
     1801 gatcgaacaa aacatatcat ctaattgatt ggcttttgtt aatgctacga tcaagtccac
     1861 gtgttcgttg ctttcgatga tttcttctgg tgaatagatt ggcagttttg cgaccacttc
     1921 tttaccgtta aagtcagcaa tcaacccatt tgtacgaatg gcttcaatgt gagcaggcca
     1981 acgatcgatc aagaggacct catttccgct ttgatgtagc atcaatccga ttcggctgcc
     2041 cattgctccg gccccagcta ttgcgatttt catgtttttt ctctccttta ttcaatgagt
     2101 tcccttttag tatatagaaa aatggaagaa aatagcattg ttttgtttga aaaaaatgaa
     2161 aaaaagtgtc ttacttaaga agaaagtgag ggatacagat ggatattttg gcggcaattg
     2221 attcatttaa aggaagtgct tcttcatttg aactaaatca ggcagttcta aatggctggg
     2281 aagatcgtaa aggaagaaaa atcaatgtgc cgattgcaga tggcggagaa aatactgcag
     2341 aagcaatcta ttacgcgctc aggggaacat ggcgtaccat tgatgggatg gatctcttat
     2401 tccgtcagcg aaaaatcagc tatttattga caacttggca aggaaaaaac accgcagtca
     2461 tcgaatctgc acaagcattg gggttagatc tacttgataa accaacggat caaactatcc
     2521 gacttgcttc cagttatgcc ttaggagaac ttattaaaga tgcactgctt caagaagtag
     2581 aacaaattat tgtcacttta ggaggaagcg ggtgtagcga tggtggtcta ggattactcc
     2641 aatccttggg tgcttcttta gaagggtaca cagaaggaaa tcctttatta tctactaaaa
     2701 aacttcattt tgatcgaaga aacgttcttg tttctaaagt aaaattgatt atcgctgcag
     2761 atgttaccaa tccatataca ggtcaacaag gagctgcttg gcaatttgga agacaaaaag
     2821 gaggaataga tacgacgcta gctttcttag ataaacaagc aggaaagatt gctcagcaaa
     2881 taaaagattt ctgggaggtg gatttagatg atattccagg aagtggagca gcaggcggta
     2941 ttggtggagc cctttttttg ttgggagcga agatggtttc tggtttcgat ttagtcagcc
     3001 aaatcactgg attggaaaaa aagatcgaac aagcagatgt catcattaca ggagaagggc
     3061 ggatcgatca gcaaacgatc cacggaaaag ttccatacgg tgtagcagtg cttgcaaaaa
     3121 aatatcgaaa accaataatc gctatttgcg gaagtagaga ccaagagcta gaaggacttt
     3181 ctgattttct cccaattgtc ttaagtattc atttgggtcc aataggttta gaagaagcaa
     3241 tggaacacag gcaaacatta gaaaaaacaa aaatcttagg acagacactt agcagatttt
     3301 tcaccatcct cccgaagtag ttgacaaaat cattttcttt atgctatcgt aatttcaaat
     3361 ataggacaaa gtgagggatc cgtgcattga aaaattaagt cgattgatga aagctgcatt
     3421 cagactgtac cttgtggaga caaggaagca gtgtgcagat tttcgggatt ggcttggttt
     3481 tttcgatgta tgggtctttt tgtgtgtatc caacccttgc atcctcttta gccagttctg
     3541 aaaataggac tggtcttttt ttacgaggtg atggaaaatg tctaaaatcg aaataaaaaa
     3601 tctgacattc ggctacgaca gccaaggcac attattattt gaacaagcaa atctaaattt
     3661 tgacacacaa tggaaactag gacttatcgg acgaaacggt cgaggaaaga caactttact
     3721 gaatattcta caaaacaaac taccttatca agggcaagta atccatcagc aagaatttgc
     3781 ctatttcccg caacagacaa aagataaaga acgtttaacc tattacgtgt taaatgatat
     3841 tacggatttt gagatatggg aaatcgaaag agagctccaa ttgatgcaaa cagatcctga
     3901 aatcttatgg agagaattca gcacactatc ggggggagag aagacaaaag tcctactggc
     3961 acttttattt gtggatgaca ctcatttccc gttaatcgat gaaccaacga atcatttgga
     4021 tatctctggt agaaaacaag tagcggctta tttgaaaaag aaaaaacaag gcttcatcgt
     4081 ggtcagccat gaccggggat ttatcgatga agtagtggac catgttttag caatcgaaaa
     4141 aagtcaactg gaactttatc aagggaattt ctctatctat gaagaacaga aaaaacttcg
     4201 tgatgaattt gaaatggctc aaaatgaaaa attgaaaaaa gaagtcagta ggctaaagaa
     4261 aacagcagct gaaaaagccg aatggtctcg ttcccgagaa ggagataaaa caaagaaaca
     4321 agtcggattc atcgatactg aatctagacg agtgaataaa ggagcagtgg gtgctgatgc
     4381 tgcacggacg atgaaacgat ccaaagcaat cgtgaatcgg atggagaccc agatcagcga
     4441 gaaagaaaaa ctattaaaag atatcgaata tatcgattct ttgacgatga atagccaagc
     4501 gtctcaccat aagcgacttt taagcgtaga agatcttcaa ttagggtatg aaaatctgtt
     4561 attcgagcca attcatttta caatcgagcc tcatcagcgg gtggcgattt caggtcctaa
     4621 cggtgcagga aagtcatcca ttatccatta tcttctgggg gcattcaacg gcaaggttat
     4681 aggagaaaaa taccagccaa aacatctgag cattagttat gcaagccaaa attatgaaga
     4741 caatcgagga acgttggcgg aatttgcaga gaaaaaccaa gtagactacc aagcattttt
     4801 gaacaacctc cgaaagcttg ggatggaaag agatgttttt cataacaaga tcgagcagat
     4861 gagtatgggc caacggaaaa aagtggaatt ggctaaatct ttatcacagc cagctgaact
     4921 atatacatgg gatgaaccat tgaattattt ggatgtcttc aatcaagaac aattagaaca
     4981 actgatcttg aacgtgaaac ctgccatgtt actagtggaa catgatcaaa ccttcctgga
     5041 taaagtatct actgagatta tttctcttga gagaatctaa cccttgtaat ctcaagaaca
     5101 acaaggtatg gttaagggga actttgccaa cgaaggagag aatcacatgc tttatgtaac
     5161 gagacacgga gaaacaactt ggaacgcaca aggattagtt tgcggacggg cagatgtgcc
     5221 gctgactgaa aaaggacaga tgcaggcaca gaaactagca gaaaaggtag tagatttgcc
     5281 tgttccaatc acgaaaatca tccattcccc tcttcaacga gcaagagata cagcacaagc
     5341 agttgctgat cgtctcagct tgccgctgac cgttgatgaa cgattggtag aaatggattt
     5401 tggggattat gatggactgc caagcaaaga tgagaacttt caaaaagcac gtttagcgtt
     5461 cgctgtacga ttcccaaatg gggagtcagt cttagatgtg tatgcacgga tcgttccttt
     5521 attgaaagaa tgcatcgaag acgaagaaaa tgtctatctg ttagtttgcc ataatgcctt
     5581 gataagagtg atcaatgctt attttcatcc gatgcctaat gaggggttct ttacattcat
     5641 ggtagataat acataattgg tttcttatga gtaattatgt ttttgtgtta tttaaataaa
     5701 atatttcaag gcactgcttt tgcttagcag tgcctttttt aggttatgac aattcttttg
     5761 ataatataaa ctcaaccttt agaaatgaaa tttaattatt ttaataaaag tattgaaatt
     5821 ttgtttcttt agatatatac tctagtcata gaaatgaaga cggatacaga aaaagaggga
     5881 taatatgttt ggcttttcaa tatttatgaa cgattctttg tcagaagaga agaaacagta
     5941 tatccgccaa atggcatcca atggctttgt cggtattttc acttccatgc atataccaga
     6001 agatgatgtt tcggcatatc aaaagcgatt gatcgaacta ggaagcgaag cgaaaaagaa
     6061 taaactagaa ttgatggtcg atatttcagg agaggcattg gaacgagcgg gtttttcatt
     6121 agaagatcta acgcctttga aagcaattgg tgtaacaggt ttaagaatgg attatcatat
     6181 ttccaatcag cagattgccg actggtcaca tcaattgaaa atcagtttga atgctagcac
     6241 gatcacgcct aaagatatcg atgaattgaa agaagcagaa gctgatttct cacagattga
     6301 agcttggcat aattattatc cacgtcccga aacagggctg gacaaagaat ggtatcagaa
     6361 aaaaaatcaa tggctcaaaa ttcaaggtct ccttgtccaa ggttttgtac caggagatac
     6421 agagttgaga ggcccactat atcaaggatt gccaactttg gaagaacatc gagggatcca
     6481 tcctcttgca ggcgctctag atctattagc aagtaacacg gatattgttt acatcggaga
     6541 tgcaggtctg tcagaaaacg ttcaggagca atttgcttct ttccaaaaag aacagacagt
     6601 cttgctccat acggaacctg tagatgaaga attttacgaa tatatattag ggaagcatac
     6661 gaatcggcaa gacgatgcaa gagatgtcat acgaagcgta gatgcacgtt ttcgagagat
     6721 tccgcctatc ccagcaagaa atacagctac gcgtatgaaa gggtctatta ctttagataa
     6781 cgaaaagtat ttgcgctata tgggtgagat ccaattaacc aaatatgatt tgccagcgga
     6841 tgaaaaagtg aatgtagtag ctaaagttat caaagaagag ctaccattga tcaaccaaat
     6901 caaagctggt atgaactatc aatttataag aaaagaagga agataaaaat gagcaaaatc
     6961 aatttagaga acctaacaac ggaacgcaga aaccaagaaa cttttggatt agatgagatg
     7021 agtatttctc aagccgttca actaatgaac aaagaagatc agaaagtggc cgctgcggtt
     7081 gaaaaagaac tgacaagtat cgaaccagtg attgctaaca cgattgagtc ctttaaaaaa
     7141 ggtggacgtc tgatttatat gggagccgga acaagtggaa gactaggtgt gttagatgct
     7201 gctgaatgcg taccgacatt cggtgtagaa ccggaaatgg tcataggtct aattgctggt
     7261 ggagaagaag caatgactgt agctgtcgaa ggggccgaag attcttatga gctagggcaa
     7321 gaagatctaa tcaagctgaa tttgacaaaa aatgatatag ttattggtat cgcagctagc
     7381 ggtcgtacac catatgtgat cggtggatta gattacgcaa aatcgatcgg tgctgtcaca
     7441 ggaacgattt cttgcaataa acaagccgaa atcagtaaac acgcggattt cccaatcgaa
     7501 gtcgatgcag gtccagaatt tttgacaggc tctactcgat tgaagtcagg aacagcacaa
     7561 aaacttatct tgaatatgat ttctactatc agtatgattg gtataggtaa agtattcaat
     7621 aacttgatgg tcgatgtcaa accaacaaat gaaaaactaa tcgaacgctc aaaacgaatc
     7681 atcatgcaag cgacagaagc tgattacgaa acagctgaaa agtactttga agaagcagat
     7741 caaaatgtta agctggctat cgtcatgatt ttgacaaata gtgataaaga ggaagctcaa
     7801 gcaaaattag ctgaagcaaa cggatttgta aaagggacct tatgaggggg aaaagaccat
     7861 ggcaaaaaac gaactgactt tggaagaact ggcaaaacaa atttataaag gggcaggcgg
     7921 catgggcaat gtagaaagca ttgtccactg catgactcgt gtgcgtatga agatcatcaa
     7981 tgatgatctt gtaaatgtct ctgaattaaa agcgattcca ggagtgcttg gtgtagtaga
     8041 agatgaacag cttcaagtca tcatcggacc tgggaaagtg aacaaagtag cacagcaaat
     8101 ggttgatttg gcaggcgtga aattaggaga aaaactttct tctgtaagta cagctacagc
     8161 aaattcatca gcatctggaa aagaccgtgt aaacgaacgg gcacaagaaa tgaaagcggc
     8221 acaaaaatcg aaacaaaaac catctaaaat caaatcggta ttaaaagaca tttctaatat
     8281 ctttgtgcca atgattcctg catttgtcgg tactgggatc gtggcaggga ttgccgcagt
     8341 tttagcaaac ttagtcacag ccggaacact tgatgcagca acatggcaac aatatatcga
     8401 tgtgatgaac atcttgaaaa acgggatgtt tagctaccta gttatctata caggtatcaa
     8461 tgctgcacaa gtttttggtg caacaccaac tcttggtgga gttatcgggg ccgttgtgat
     8521 gctgacaggg atgaatccgg aagcaccact gaaaaactta tttactggtg aagctcttgc
     8581 agctggacaa ggtgggatcc taggtgtcat cttcgctgtt tggctattgt caatcgttga
     8641 gaaaaaactg cataaagtag tacctgatgc ggtagatatc atcgttacac caactctttc
     8701 attgattgcc atcggtctga ttgaaatttt cttcatcatg cctttagcag gtttcatttc
     8761 tgatggcatg gtcggtggga tcaactgggt acttggcgtt ggtggagcat ttgccggctt
     8821 cgttctaggc acattattct tgccgatggt tatgttcgga ctgcatcaaa ttttgactcc
     8881 aatccatgtg caaatgattg atgaaactgg tcgtacgcta ttgcttccaa ttcttgcgat
     8941 ggctggtgca ggacaagtgg gtgcagcatt ggcattatgg attcgctgca aaaaagataa
     9001 agaattaaca gaaatgatca aaggagcttt accagtcggg atcctaggaa tcggcgaacc
     9061 attgatttac ggagtaacat tacctctagg acgcccattt attactgctt gtatcggtgg
     9121 aggtatcggc ggggcagtga tcggaatgat cggaaatgtc ggggctatcg ctattggacc
     9181 ttcaggagcc gctttgatcc cattgatctc tgacggtaaa tggttaggct acatccttgg
     9241 attattggca gcttatgctg gtggcttcgt tgctacattc ttcttcggta ttcctaaaga
     9301 ccgtttagaa aaagaagaat tagcgactga aacagccaca gtaaatgaag tgcctgaaaa
     9361 agtagtacct caaacttcag ctgaaagtgt gactatcctc tcatcagttg ctgacggaac
     9421 agttgtttct ttagataaag caagtgatcc agtttttgca caaaagatga tgggtgaagg
     9481 ctactttgta gaaccagaaa acggacatat ctattctcca gttactgggg tagtcagctc
     9541 tgtcttccca acgaaacacg ctattgggat cacaacgcca aatggtttag aaatcttgct
     9601 tcatatggga atcaacacag ttgacttagg cggtacgcca tttgatgtga aagtaacaga
     9661 agggcagcaa gtgacacctg atacgcttgt agcagaagct gacttagaag cgatcaaagc
     9721 agcaggcaaa gaaacatcca tgatcgtctt ggtaaccaat atggatcgtg taaaaaactt
     9781 tgtcttggaa aaaacaggta aagcaaaagc aaaagcacct gtgatggatg tcaaagctta
     9841 atatgataga aacaatagaa acgaaagaag aaactgaaat ctatttttca gcttcttctt
     9901 ttttattatt tattgttttc tgctaaaatc tgataaattc gtgtcacatc agatggtgtt
     9961 ccccgtaatt cataatctgc caagaaagga aagccaaatg tttgtgcata ttgtttggct
    10021 gttagacaat actgattatt gaagttttta tttccgctac cgactacacc aagacaaagt
    10081 ttatgattgt cttcatgttc cagatattca cgcatcgttt cggtcaagat ttctgtatca
    10141 ccgttatcta aaccatttcc gccgtctaaa taagtaggaa cgaaagtaaa aaatggttct
    10201 gtttctttcg taaaatcact attttcatgg atttctttta aagtaacttc aggattgaca
    10261 ggatcttctg catgcatttt ttcagcatat tctgctagat gtttggcaaa ggcacgcgta
    10321 tttcctgaaa tcgatatata taaaatgttc atggatcatc ctccaattct ttccttttag
    10381 tatagcatct tttttaagtt ttttggtggt gtaatttgga aagggactag gcgctttgct
    10441 tgtataatga gaaaaaagcc ggtagaatta tat
//
LOCUS       DACGEU010000272         9516 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.guided.103, whole genome shotgun sequence.
ACCESSION   DACGEU010000272 DACGEU010000000
VERSION     DACGEU010000272.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9516)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9516)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9516
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.guided.103"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            122..2008
                     /locus_tag="IXR40_002990"
     CDS             122..2008
                     /locus_tag="IXR40_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAQ4362748.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            2020..2967
                     /locus_tag="IXR40_002991"
     CDS             2020..2967
                     /locus_tag="IXR40_002991"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HAQ4362749.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            2987..3514
                     /locus_tag="IXR40_002992"
     CDS             2987..3514
                     /locus_tag="IXR40_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAQ4362750.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(3577..4230)
                     /locus_tag="IXR40_002993"
     CDS             complement(3577..4230)
                     /locus_tag="IXR40_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HAQ4362751.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            4362..5204
                     /locus_tag="IXR40_002994"
     CDS             4362..5204
                     /locus_tag="IXR40_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAQ4362752.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            5362..6258
                     /locus_tag="IXR40_002995"
     CDS             5362..6258
                     /locus_tag="IXR40_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HAQ4362753.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            6261..6974
                     /locus_tag="IXR40_002996"
     CDS             6261..6974
                     /locus_tag="IXR40_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HAQ4362754.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            6994..7512
                     /gene="msrA"
                     /locus_tag="IXR40_002997"
     CDS             6994..7512
                     /gene="msrA"
                     /locus_tag="IXR40_002997"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAQ4362755.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            7509..7736
                     /locus_tag="IXR40_002998"
     CDS             7509..7736
                     /locus_tag="IXR40_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HAQ4362756.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            7888..8439
                     /gene="lepB"
                     /locus_tag="IXR40_002999"
     CDS             7888..8439
                     /gene="lepB"
                     /locus_tag="IXR40_002999"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HAQ4362757.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(8522..9064)
                     /locus_tag="IXR40_003000"
     CDS             complement(8522..9064)
                     /locus_tag="IXR40_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HAQ4362758.1"
                     /translation="MNTLIAKDVFRLPEMNARLLSTSALLLALDVILYKIAIGPAYFQ
                     ITFGFLSMALMGYLYGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLF
                     LYHKKINLPSVIAAQLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQI
                     MVVYSFIKTLEARKVFKRAV"
     gene            complement(9301..>9516)
                     /locus_tag="IXR40_003001"
     CDS             complement(9301..>9516)
                     /locus_tag="IXR40_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HAQ4362759.1"
                     /translation="DKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHEVDM
                     GMPEEEMFSLEVQDLDGNTLEPVWMKM"
BASE COUNT         3412 a         1660 c         1889 g         2555 t
ORIGIN      
        1 tatcagaaca ggatcgaatc ggtcctgttc tttttttgag aacacaaaaa gaacaaatac
       61 caaaaaaatt ttcctgaagt tcactatttt tatgatacaa tatccaagat aaggagggaa
      121 catgttgaaa gaattaaaag taactgacct caaaaaaact tatggtgaaa aagatttgtt
      181 tgaccagatt tcttttttgg tccacgaaaa agaccgtatc gggttgattg ggacgaacgg
      241 gacgggtaaa acaagtctct taaatattat tgccggtatc gatagcagcg acggtgatcg
      301 gcaaacagtg ttttatccaa ctgattaccg tattggttat ctttctcaag cagctgaatt
      361 ttccgatgaa ttaactgttc tccaagcagt ctttcaagga aacagcccct tgatccaaac
      421 tgttcgagca tatgaggaag cattgatcga actaggggaa aacggagaag accctgatgt
      481 gcaaaaacgt tatgctaaag cagaagaaca aatgaataaa gaagatgctt ggactacaga
      541 taccaacgca aagattattt tgcaaaaatt aggaatcagt gaattagata aaaaaatcag
      601 tactttatca ggtggtcaga aaaaacgagt tagtctggcg caagtgttga ttgatgaacc
      661 cgatttacta ttactagacg aaccaacaaa ccatttagat tatgaagcga tcgagtggtt
      721 ggaaaactat ttgaaacaat accgtggcgc actattgatg gttacccacg atcgttattt
      781 tctagataga gtagcaaacc gaatcttcga actttcattt ggaaaattat acgagtataa
      841 aggaaattat gaagcttacg tcttagaaaa agcagaacgt gatcgtgtag aagtagaaca
      901 agaagaaaag cgcaagcggc tttataaaca ggaattagct tggatgaggg ctggcgtaca
      961 ggcacgtggc accaagcagc aagcacggat caaccgtttc gaagatctaa aggagaactt
     1021 gtaccaagta aaccaagaag atgatttaga gctgaaccta gcgacacaac gtttagggaa
     1081 aaaagtactg gaaatcaaag atggcagtta ccgtataaat gaccaaacac tgctagaaca
     1141 tttagattta ttgattcaat ctcgggaaag actaggtatt actggtaaaa atggtgcggg
     1201 aaaatcgaca ttgcttaata ttctagctgg cagaattccc ctggatagcg gtacaatgtc
     1261 tatcggtgaa acggttcatc ttgcgtatta tacacaagaa aatgaagaaa tggcaccaga
     1321 taaacggatg attgcttact tacaagaagc tgctgaagaa gcaaaaacag cagatggcag
     1381 tcaaatcgga gtagcagaat tacttgaacg atttttattt ccaagattta tgcatgggac
     1441 actgataggc aaactttcag gcggagaaaa acgccggtta tttttgttga aactgctgat
     1501 tcagcaacct aatgttttat tattggatga accgaccaat gatttggaca tagcaacatt
     1561 gacgattttg gaagattatt ttagaagttt tccaggtgct gtgatcactg tttcccatga
     1621 ccgttatttc ttggacaagg tagcagataa gttattagta ttccaaggaa acggaaaaca
     1681 agaactttat tacggaaaca tgtccagtta tttactgaag caaaaagaga cccagcagcc
     1741 tgctgaaaaa gcgaaaccaa aaatacagag caaggaacct gctgaaaaga agaaattatc
     1801 ttacatggaa caaaaagaat gggaaacgat tgaagatgag attgcagaac ttgaagaaaa
     1861 aatctcattg ctccaagaag agatgaatca tcaaggagat aatttcactc gattacaaga
     1921 attgcaaaac gacgtatctg aaacagaagc acaacttgaa gaaaaaatgg cacggtggga
     1981 atacttgagt gaatgggtag aagattagga ggaaaaagga tggaacaagc gtatcttgac
     2041 ttaggaagaa aattgttgga agaagggcat cgtaaagaag acagaacagg cacaggcaca
     2101 ttaagcttat tcggatacca aatgcggttt gatctgcaaa aagggtttcc tttgttaaca
     2161 acgaaacgag taccttttgg attgatcaaa agcgaattgc tttggttttt aaaaggagat
     2221 acgaatatcc gctatctatt acaaaataaa aaccatattt gggatgaatg ggcatttgaa
     2281 cgctacatca aaagtccaga ctataatgga ccagatatga ctgattttgg ccatagatgt
     2341 ttgacagatc ctgaattcaa tgaagaatat aaaaagcaga gcaagctttt ttgcgagaag
     2401 atcctaaccg atgattcctt tgctgaaaca tacggcgatc ttggacacat ctacggctat
     2461 caatggcgtc actgggaaac aaaagacggt ggctttatcg atcaaatcaa acaagtgatc
     2521 gaagcaatca aaaagactcc tgattctaga agattgatcg tttctgcatg gaatccggaa
     2581 gatgttccta gcatggcttt gcctccttgt catacgatgt ttcaatttta tgttcaagag
     2641 ggacggctaa gctgccaatt gtatcaacgc agtggggatg tgtttctagg cgttccgttc
     2701 aacattgcaa gttatgcgtt gctgactcac ctaattgcac atgaaacagg tttagcggtt
     2761 ggcgaatttg ttcacacatt aggagatgct catctttata tcaatcatat cgaacaaatg
     2821 aaagaacaat tgagccgaga aatacgcgca tttccgactt tagttttgaa tcaggaaaag
     2881 cagtcagtat ttgattttga gatggaagat atccaattag aaggatatga cccacatccg
     2941 gcgatcaaag ctcctatcgc tgtttagaat cagaaaggat gagaaaatgt tagctgcaat
     3001 ttgggcacag gatgaaaacg gattgattgg aaaagaagac cgtcttcctt ggcgtttgcc
     3061 aaatgatctg aaattcttca aacaaatgac agaagcaaat acactagtga tgggacgaaa
     3121 aacattcgaa gggatgggta gccgtccgtt gccgaatcgt cagacgattg ttttgacgag
     3181 agattcttcc tataaagcag aaggcgtgca tgtcatgcat agtgtggaag acgtgcttgc
     3241 tctggaaaaa gaaacagacg gtatcttttt catcgctgga gggtcagctg tttatcaaga
     3301 atttctgcca ttttgtacga tattataccg tacagtcatc catcatgtat tcgatggaga
     3361 tgcttatttt ccacctgttg actggtctga ttggtcactg atcaatacta gtcaaggaga
     3421 aatggatgaa aaaaatcgtt atccgcatca atttgaaacg tatcagcgta atgagaatcc
     3481 tgtaaaaagc gggacaggcg aattgacgat ataaaaaagc tatggataga ctagctgtta
     3541 tttagagctg tcccatccat agctttattt tttttattaa gtaaagaata aaacagagaa
     3601 gtacataaaa cctgcaccta acataacaaa caaatgccaa acaacatgca tatagcggat
     3661 agaattcaag ctataaaaga atgcgcctat cgtgtaagaa agcccgcctg ctaccatcaa
     3721 aataacacca gtcattccaa gagagtgata aagaggaaca gcagccacga cacagagcca
     3781 ccccataaaa atatagatga tcgtagatac ttttgatact ctctcccgtt tatgcaacgt
     3841 caacgcttta tatataatgc caagaatcgc aaacaaccag attaatacaa ataaagtcca
     3901 acctagccat cctcggatac tcagcaaaca aaaaggagta taacttcctg caatcaaaag
     3961 aaaaatcgaa ctatgatcga atacttggaa cacctttttt gcttttgtaa aaatcaatga
     4021 atgaaacaaa gtagacgtta aaaataaaag aatcatcatc gatccataga tagcataaga
     4081 gacaatatgg agggaggaat gcaagtgggc accttttact aaaagaacca ctagtcccgc
     4141 gatactcaat ccagtcccaa ttccatgggt gactgcatta aacacttcat ttaatatttc
     4201 atacgttcga ttaaatttcg ttttttccat gaaaacggct cctttactag gtgtaattaa
     4261 tgaaaaatca ttatttgtct gttatactaa aaatagaaat tgtcttacat gtagtttaac
     4321 atgaataagg catcttgtta aagaaagaga gagagaaaat aatgacaaat gtaaaaatcg
     4381 taacagattc ttcatgtacg atggaaaaaa atgtacgcga tgctttaggc attcgtgtca
     4441 tgccgctatc catcatgatc gacggaacag tatatcccga tgatgaccaa ctagacggcg
     4501 aaagatttat ggaaatgatg gcgaaagcaa aaaatctgcc caaaacaagc caaccaccaa
     4561 ttggagaatt catctcgatg tatgatgagc taggagaaga cggcagtgaa gtgatttcga
     4621 tccatatgac aaaaggcttg agtggaacag tagaagcagc aagacaagcc agtaatctaa
     4681 caaaaacgaa agtaacggtt atcgacagtg ataccactga ccaaggatta tcttttcagg
     4741 taattcgagc agctgaatta gcaaaagaag gtaaaacagt agagaaaatc cttgaagaag
     4801 tcaaaaaagt acaagacaat acaaaattat acatcggaat atccacacta gataacttgg
     4861 taaaaggtgg aagaatcagc cgaacaactg gtttgctgtc tagtgttttg aacatacgcg
     4921 tggtgatgaa tttcgcccat tctgaattaa tccctgtaac taaggggcga ggaaagaaaa
     4981 cgttcgataa atggtttaat aatttgaaaa atgaactgaa agaattgcca aatgtgcgac
     5041 aaatcggtat ttcacatgcg gatgcaaaag aattggcgca agaattcaaa gagggtttgc
     5101 aagaattatt cccggacatg catatccctg tactgcatac gaatccggtt atcgctacgc
     5161 atactggtaa agacgcgttt gcaatcatgt attatgtaga ttagtcgaaa agaggataag
     5221 ccctcagcct gaaaggcttg cagcttattc tctttttctt tataaaatta ggaaaataat
     5281 tgttttcttt tttcataaag actacctttt tgataaaatt tttgataaca ttagaaccaa
     5341 tcgaatacaa gaggtgaaaa aatgaaatta acgaaacgac atttgatcct cgttttgttc
     5401 ccattattaa ttgcgatcat catctatgca ggtttagctg cttctatacc gaaagctggc
     5461 ccactaatga aaccagtaac tactgtgaga gaagatccaa ataaaaaaga aaaacttcac
     5521 tacatagcta tcggagattc gctgactgaa ggagtaggag atcaaaccaa gcaaggagga
     5581 ttcgttcccc ttgtcgcaaa tgatctaaaa gaccgttata atttgaccgc ggttgaaaca
     5641 gaaaactatg gtgtaaatgg tgaacgaagt gaccagatct taaagcgagt aaaaacaaaa
     5701 gaagaaattc gaaacaatat caaaacagct gattttatca cactgactgt tggcggtaat
     5761 gatttgatga aagttatcca aaataattta ttcgggttaa cggtcaattc ctttaaaaag
     5821 ccactgaaaa actatcagga aaatgtcaca gaactattgg aagaatttcg atccctcaat
     5881 aaaaccgcac ctatttacat tttaggcatc tacaatccat tttatttgaa ctttcctgag
     5941 atcactgaca tgcagacaat tgttaacaat tggaacaaag gaacagaaac ggtgacaaaa
     6001 aaaatgccga actgctactt tatcccaatc aatgatttgc tttatcaagg attgaatcag
     6061 gaagtaggtg tcacagaaga aggaacagat caaacaacta gcacgacaga aaatctaaat
     6121 ggcatcaaaa ataatgtgct ctatgaagaa gatcatttcc atccaaataa tttaggttat
     6181 caattgatgg caaatgcagt gagagatcag ctgatcgaga cacaaaacca atggttagag
     6241 aaggaggatg atcaataaac atgaaaacaa gatctgacgt atcttcaaac aaaacaaaga
     6301 aaacaaatta ctggaaattc gccttcctta tccttcttgg ggtagtactt ggttcgaccg
     6361 tatttttagg cagccgtatt tttgctaatc gggaaccaga actcccagaa ataccagctc
     6421 ttacggaaag acaaggagat cctgtcttaa cgatcaattc aaataaagaa aaagtcaatc
     6481 aaatcatcag ctttttcctt agtgagtatc aaaaagatag tgatattgaa tataaatttt
     6541 atttggaaaa tgaagcacta ctcaatggta ctttcgaagt actaggtttt cctatcgatt
     6601 tctatttata ttttgatccg tatgtgatgg aaaacggaaa tgtccaacta aaagctagaa
     6661 gtctttctat cggaacattg agtttgccaa tcaaagatgt gatgaatatg atcaagagaa
     6721 actataaatt accagattgg atcgaagtca atacagatga tctgactatc atgcttaggt
     6781 tggatcaatt ccgaatgcaa aacgggatgt atattaaagc agataaaatc gacttagtaa
     6841 atgatgacat tcggtttagt ctatatttgc caaaagatac ctctgatgct tcaaacaact
     6901 caaataccaa caaaactagc accagcagta ctgaaagcaa gacaaaagaa aataaaaaat
     6961 catcggatga gtagtattag agggggaatc ataatggaac gagcaatatt tgcaggaggc
     7021 tgcttctggt gtatgatcca gcctttcgac acgcttcctg gtatccatac agtgatgtca
     7081 ggatatactg gagggcatgt accagatccg acttatgaac aagtaaaaag ccaaacgact
     7141 ggacatacag aagcagtgga gattatctat gatccaacat tgatttcata tgaacaatta
     7201 gtagaacttt actggcagca aactgatcca actgacgctt tcggacaatt cgaggatcgc
     7261 ggtgacaatt atcgcccggt gatcttttat ttgacagaag aacagcggat cattgctgaa
     7321 aaaagtaaga aacagttagc tgaaagtgga cgtttcgaac agccaatcgt tacaaaaatc
     7381 gaaccagccc aaccatttta tctagcagaa gaagaccatc aagagtatta taaaaagcat
     7441 cctgaaaatt ttaaaagaaa ccatgcacgc cgggctgcct ttatcgaaga aaattggagg
     7501 aacgaagggt gaatcgaagc ttttttcatt atttaatgac actgcgaggc ggtggcacac
     7561 atgatgcttt atctgttttc gctacagaag ccggtaaaga catccaattt cctaagcaca
     7621 gctctagcta cgaagaaatt tctaattatc tggaactgaa tgtcgactat ttgccgtcca
     7681 tggatatctt tgacgaagca tgggaaaaat atttagaaaa taatcatgac atataagaga
     7741 tagttttgta ctttatgatc aaaaaagttt tttgtccaat agcctaattg aaagaattat
     7801 ttttatttca gctatctagt cgcatttttt tgatattttt cttataataa agaaagaatg
     7861 aaaaaaagag ggatggattg atagagattg acaaaaaaac aacgctatat taatcgcttc
     7921 tggcttgtat tcaaatactt acttgtttct gtattccttg cgttcatgtt gcggggattt
     7981 ttattcatcc cggtaccagt ggaaggcaat tcaatggaaa acgtgttgaa gcaaggtgat
     8041 atggttgtga tggaaaaatt ttcggagatc agacgatttg atattgttgt ttttcaatta
     8101 gcagatggca cgatttatat caaacgagta atcggtcttc caggagaaaa tgtcagctac
     8161 caaaatgatc aattgaagat caatgggaaa gtagttaagg aaccttatct aactaaaaac
     8221 ctgaaatcag atcatgcaaa tgcatcctat acgacggact ttacactaca agagctaacg
     8281 ggacaatcca agcttccgga agataattat tttgtacttg gagataatcg aagagtttca
     8341 aaagatagtc gttcgtttgg cacgatcaat aaaactgata ttctaggtaa agcaagattt
     8401 gtctattatc cacttgatga aataaaatgg atccagtgag aaacaataaa gcgtgcagtc
     8461 tgttgagact gcacgcttta ttgtttaatc caaaatcagt ttactacctt agtacgtaaa
     8521 atcaaacagc tcgtttaaac acttttctag cctctaaagt tttgataaat gaataaacaa
     8581 ccattatttg aatagggatt tggatcatat tcctgatgaa tctacctaga aaaattactt
     8641 tgaaatctgc accaaacaaa acagacatca gccaagaatt gataaaaagg ctgactggga
     8701 tcataatcaa taattgggca gcgatgacgg aaggcaggtt tatcttttta tgatataaaa
     8761 ataagccatt aataaatcca ccaaggaaag ccgtgataag aaaagcagct tgaaacgttc
     8821 ctgaaccaaa tatcgtgaaa tttaaagtgt tcgacaacat ttcaagcaaa ccagcccaga
     8881 tcggtccata tagataaccc ataagcgcca tacttaaaaa tccgaatgtg atttgaaaat
     8941 aagcaggacc aatcgctatc ttgtataaga tgacatcaag ggctaataaa agagcagagg
     9001 tcgacaacaa tcttgcattc atttcgggca atctaaaaac gtcttttgca atcaaagtgt
     9061 tcaaaatatt ctctcctttg tcagttaata ataaaaggat accataaaat caccaatgtg
     9121 tcatgacaca ttggtgattt acatacactg gcatctaaca attaaaaaaa gggtgagaag
     9181 actgctttta taaactgtaa aaaagagatt gtacgaataa aaaaaataga ggcggagaat
     9241 acttatcgta tcatccgcct ttgttttttt gttataaaaa acgtcagatt agttatctgc
     9301 ttacatcttc atccatacgg gttctaatgt atttccgtct agatcttgga cttctaatga
     9361 aaacatttct tcttcaggca ttcccatatc tacttcgtgg aaagtaccac cattttcttt
     9421 tgcaatttga gcaaattttt ttacttcatc cgcattttca acactaaacg aaatcaaagc
     9481 accacttgtt tttttattat cagctatttc tttatc
//
LOCUS       DACGEU010000273         6916 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.guided.120, whole genome shotgun sequence.
ACCESSION   DACGEU010000273 DACGEU010000000
VERSION     DACGEU010000273.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6916)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6916)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6916
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.guided.120"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            <1..298
                     /locus_tag="IXR40_003002"
     CDS             <1..298
                     /locus_tag="IXR40_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362760.1"
                     /translation="KEELAKNLEEAKLKISELETIIELQKQQLENFNKKEDSTHKDYS
                     EQLNSIEESVYKLLINSGLASKELEEERAEPEQESSRLGEGTMFSSPSLRFTTD"
     gene            365..1900
                     /locus_tag="IXR40_003003"
     CDS             365..1900
                     /locus_tag="IXR40_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362761.1"
                     /translation="MVGDDMTEHIFNRKSASIILKAKFETGKSKKNNHMVELQKFVDY
                     ISRQEAIRQDKLDHDYSEDELNELARIEKALEKIEQETDQPVIKDLREMDKYIDYMTR
                     KKAILENVDNEIVNGAFSNTKRYITKKDISKIKESVIEAKNNGSVMFQDVISFDNDFL
                     VREGYYNPETNELNENVLYEATKSMMGKMQEKEELVDPFWFATIHRNTEHIHIHVTAM
                     ERKNTREIMEYDGVLQARGKRKQSTLDDMIFKFGSKILDRTNEFEKISKLRKEVPLEL
                     KQSVKDSLIQLYVENNSRYDKELVKYLKELKKEIPSTTRGYNELPEETKEKIDEVTNY
                     MTKDNPKRKEYDRMTKEIDELYQTTYGKRYNPQEYYLNRKKDFNARMGNAVVGQIKLL
                     KQSEEKNLKSNELKNLLDGKKLNVKFDREKPEFKTKYAKQSYDDFQKRLEERQLAREK
                     NEVHFKKISEKFKDKKLIRKIDRVINDDLNMYRAKNDYEVAQRMIEQEKMRQAREFEI
                     GMN"
     gene            1922..2251
                     /locus_tag="IXR40_003004"
     CDS             1922..2251
                     /locus_tag="IXR40_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362762.1"
                     /translation="MKNFDIVCSNTKNIYLRELLNSDSETIEDVKKIIVLFEKENMEL
                     ENWGLFEIPISGNYCFYNWKTEDDVAFANYFFDKNYFSPLYIDKHSNEQVASSIKEAI
                     KLERVRK"
     gene            2253..2516
                     /locus_tag="IXR40_003005"
     CDS             2253..2516
                     /locus_tag="IXR40_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362763.1"
                     /translation="MIDFRTVMDKLSNGDFRVLIELYLNVTSTVKEFLYSNPKTALVL
                     VAVLIVFAVISFIKKMIPLLIIGAVLILGLYFPEVLDQIKNIF"
     gene            2691..3557
                     /locus_tag="IXR40_003006"
     CDS             2691..3557
                     /locus_tag="IXR40_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362764.1"
                     /translation="MKKLRVIATIPMIFSFALLLSACGKEEAGAKSNEAHNISFIDSA
                     EQKDSRCWLVVETSSKNKTPIDKNEYVKAVIQTKDGKAKVFKTDMEQLTLEKVSKMSD
                     EEIIEQALNADKQKFNDKKKSDIDSYNATLDSVKTELENEEKQEFQNDQKIADFQDSI
                     PKIQADIEEIDGVQYSEPEWKMVSATIKMDNENKSPSMETVKLSYKYLDSPIWNLNSF
                     GEVSSEGELSYESTSMDLKLSIPVATTKVLDNFYSGYSNDELDQLLLTKVASKDNKVQ
                     LDSKGKNVSIVE"
     gene            3913..4410
                     /gene="dfrG"
                     /locus_tag="IXR40_003007"
     CDS             3913..4410
                     /gene="dfrG"
                     /locus_tag="IXR40_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HAQ4362765.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            complement(4482..6434)
                     /locus_tag="IXR40_003008"
     CDS             complement(4482..6434)
                     /locus_tag="IXR40_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HAQ4362766.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(6441..6737)
                     /locus_tag="IXR40_003009"
     CDS             complement(6441..6737)
                     /locus_tag="IXR40_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAQ4362767.1"
                     /translation="MQIGVLKWLQFTKQKGVHFPMQFLEPKNKNAKSVDWEISEQVRV
                     IVKQYAEYAERTESEAVDEFLLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
BASE COUNT         2567 a          963 c         1202 g         2184 t
ORIGIN      
        1 aaaagaagag ttagctaaaa acttagaaga agcaaaatta aaaattagcg aacttgaaac
       61 gataatagaa ttgcaaaaac agcaacttga aaactttaat aaaaaagaag acagtacaca
      121 taaagattat agtgaacaat taaatagtat agaagagtct gtctataaac tattaattaa
      181 tagtggatta gctagtaaag aattagaaga agagcgtgct gaaccagaac aagaaagtag
      241 tcgtttggga gagggaacaa tgtttagttc accgtcatta agatttacaa cggattgaac
      301 actaaaaaat tctaatgcaa cttagcatta agtacaaaac cgcctgtaga aaaaattttt
      361 gaaaatggtg ggtgatgata tgactgaaca tatctttaac agaaaaagtg cgagcattat
      421 tcttaaagca aaatttgaaa ctggaaaaag caaaaagaat aatcacatgg tagaacttca
      481 aaaatttgta gattatattt ccagacaaga ggctattagg caagataaac tagatcatga
      541 ttattcagaa gatgaactaa atgaattagc tagaatagaa aaagctttgg aaaaaataga
      601 acaggaaaca gatcaaccag tgattaaaga tttacgtgaa atggataaat atattgatta
      661 tatgacacgt aaaaaagcta tcttagaaaa tgtagataat gaaatagtaa acggagcatt
      721 tagcaataca aaaagatata tcactaaaaa agacatttca aaaataaaag aatcggtcat
      781 agaagcaaaa aataatggat cggtgatgtt ccaagatgta atttcattcg ataatgattt
      841 tttagtaagg gaaggatatt ataatccaga aacaaatgaa ttaaatgaaa atgttctata
      901 tgaagcaaca aagtctatga tgggaaaaat gcaagaaaag gaagaactag ttgatccttt
      961 ttggtttgca acgattcaca gaaatactga acatatccat attcatgtaa cagctatgga
     1021 gcgtaaaaat actcgtgaaa taatggaata tgatggtgtt ttacaagcta ggggtaagag
     1081 aaaacagtct acgttagacg atatgatttt taaattcggt agcaaaatat tagatagaac
     1141 gaacgagttt gaaaaaattt ctaagttgag aaaagaagtt cctttagaac ttaaacagtc
     1201 tgtaaaagat tctttgattc aattatatgt agaaaataat tcaagatatg acaaagaatt
     1261 agtaaagtac ctaaaggaat taaaaaaaga aatacctagt acaacacgtg gctacaatga
     1321 gcttcctgaa gaaacaaaag aaaagattga tgaagtcaca aattatatga caaaggataa
     1381 tccaaaaaga aaagaatatg atcgtatgac taaagaaatt gatgagctat atcaaacaac
     1441 ctacggtaaa cgctacaatc cacaagaata ttatttaaat agaaaaaaag attttaatgc
     1501 tcgaatgggt aatgctgtag taggacaaat caaactttta aagcaatctg aagaaaaaaa
     1561 tttgaaaagt aatgaactta aaaatctatt agacggaaaa aaattaaacg ttaagtttga
     1621 tagagaaaaa ccagaattta aaacgaaata tgctaaacaa agttatgatg atttccaaaa
     1681 aagattagaa gaacgacaat tagcacgtga aaaaaatgaa gtccacttca agaagatttc
     1741 tgaaaaattt aaagataaaa agcttattag aaaaattgat agagtaatca atgatgattt
     1801 aaatatgtat cgtgcgaaaa atgattatga agtagcgcaa cgaatgatag agcaagagaa
     1861 aatgagacaa gcacgtgaat ttgaaatagg aatgaattag tagaaacgga gaatagaaat
     1921 tatgaaaaac ttcgatatag tgtgcagtaa tacaaaaaat atatatttac gtgagctact
     1981 taacagtgat tcggaaacta tagaagatgt aaaaaaaatc atagtgttgt ttgaaaaaga
     2041 aaacatggag ctagagaatt gggggctttt tgaaataccg attagtggga attactgttt
     2101 ttataattgg aagacagaag acgatgtagc ttttgcaaat tacttttttg ataaaaatta
     2161 cttttcccca ttatatatag ataagcatag taatgaacaa gttgcttctt caataaaaga
     2221 agcaataaaa ttggaaagag tgaggaaatg atatgatcga ttttagaacg gttatggata
     2281 aactaagtaa tggagatttt cgcgtattga ttgaactata cttaaatgta acgtctacag
     2341 tcaaagagtt tttatattct aatcccaaaa cagctttagt attagttgca gtactgatag
     2401 tttttgctgt gatctctttt attaagaaaa tgattccgct attaattata ggtgctgtgt
     2461 tgatattagg tttgtatttc cctgaagttt tggatcaaat aaaaaatata ttttaggctc
     2521 taaaagcttc cagtagaaaa ttttgggctt tgatatttgt attaagcggt ttgaaataga
     2581 aatttgataa actacatgaa aagacattat ataagagtat ctgtgtattg gaataaaaat
     2641 atgataatat aaaattatat atcagaccga taaaaaagag gtgcttataa atgaaaaagt
     2701 taagagttat tgcaacaata cctatgattt ttagttttgc gctattatta tctgcatgtg
     2761 gcaaagaaga agctggtgct aagtcaaatg aagcacataa tatctcattc atagatagtg
     2821 cagaacaaaa agactcacgt tgttggttgg tagtcgaaac aagtagtaaa aataaaacgc
     2881 ctattgataa aaatgaatat gtaaaagcgg tgatccaaac taaagatggc aaagcaaaag
     2941 tatttaaaac ggatatggaa cagcttacat tggaaaaagt ttctaaaatg agtgatgaag
     3001 aaataataga acaagcattg aacgctgata aacaaaagtt taatgataag aaaaaaagcg
     3061 atattgatag ctataatgcc actttagatt ctgtaaaaac agaattagaa aatgaggaaa
     3121 aacaagagtt tcaaaatgac caaaaaattg ctgattttca agatagtata cctaaaatac
     3181 aggcggatat agaagagatc gatggtgttc aatattcaga gccggagtgg aaaatggtat
     3241 cagcaacaat taaaatggat aatgaaaaca aatcaccttc aatggaaacc gttaaattat
     3301 cttataaata tttagatagt ccaatttgga atttaaatag ttttggtgaa gtttcgtctg
     3361 aaggagaatt atcttatgaa tctactagta tggatttgaa gttatcaatt ccagttgcca
     3421 caacgaaagt tttagataat ttttattcag gatattctaa tgatgaattg gatcaacttt
     3481 tgcttactaa agtagcttct aaagataaca aagttcaatt agatagtaaa ggtaaaaacg
     3541 taagtatagt tgagtagatg gtaaaataag aagggataag atggttacta taactatctt
     3601 atctcttttt tatttgcatt aagtcagtga aattagatta agtagttcag ttttggagta
     3661 caaaatgaca aaatgtactt caaaatggac tacttttttc attttaactt acataccaaa
     3721 ttacatacaa aatgatttat aaaatgcaat tgaaaatgat aattgaatga aaatttgtga
     3781 ttttgtggta ttatgataat ataacttata gaaaaaattg cttattcaac taacgggcag
     3841 gataatgaga aaaggttttt tgatagaaat aagaaattag atggtaaatt agttaaaaag
     3901 gctgtgttat aaatgaaagt ttctttgatt gctgcgatgg ataagaatag agtgattggc
     3961 aaagagaatg acattccttg gaggattccc aaggactggg aatatgttaa aaatactaca
     4021 aagggacatc cgataatatt aggtaggaag aaccttgaat caatcggaag agccttacct
     4081 gacagaagaa atattattct gacgagagat aaggggttta cctttaatgg ttgtgaaatt
     4141 gttcattcaa tagaagatgt ttttgagtta tgtaaaaacg aagaagaaat ttttattttc
     4201 ggaggagaac agatttataa tttgtttttc ccttatgttg agaaaatgta catcacaaaa
     4261 atacatcatg aattcgaagg agatactttt tttccagaag tgaattatga ggaatggaat
     4321 gaggtatttg cccaaaaagg gataaagaat gataaaaatc cgtataacta ctattttcat
     4381 gtatatgaaa gaaaaaactt attgagttaa cgggtgcgtt aattgaagaa gaacagtaaa
     4441 gataaagcac aagagcttgg gattactcca agctcttttt gtcatttgaa ataaattata
     4501 tctttccaat caaattgttt atctgtaatc cctaatcttt gagcaggtgt caaaaccttt
     4561 ttatccgctg atttaaaagg gcgacaaaag ttgtagtaag ttcttagaat tgtaatcgca
     4621 aattgagcat acttcggatt gaagttagcg taaatatagc tcttcttatc accacgagct
     4681 gttgttaatg gtctttcaag agatgatata taacgtctta tctgttgaat aaagctattg
     4741 gtcgaatggt cattaacatt taatagcatc tttgcgattt cgtttggttc cagagcagat
     4801 aaatccgttc tacaatcaac tgaataaaat cctttatcct tagtggctaa tggatgtttg
     4861 atagggttat cggcatattt gcgatatctt tctccatctt tactaatagc ctcttcgtgg
     4921 aattgatgac ttgttagtaa ttcagttaga taatgagatg ccaaagtccg tagaaacttt
     4981 gttttgaatc ctctgatatc tccccaatcg agcagttctg cttttgcttg tccgaattct
     5041 tttaagcatt gttttctgct tttcgtcttg ttaacttggc aaataaaatg atgtgcatcg
     5101 ctcaacctta attctttcgt gaatactcta taaaaggcgt ttctaataga gaagtcatca
     5161 tcactaatca ttcgccattc gtcggcatta accatttgtt taattaacca atagtgagca
     5221 gttgtagtat aaggagcatc aacatttaaa ccatcgacaa atctactcct attagtaatt
     5281 ttccctaatt cgtgaagata agcattccta ttttcgctat cgttagcgga tggttcttgt
     5341 ggataataag accaatctaa cctatcattt ttacgactaa aagtattgag atggtcttct
     5401 ttgaattttc ttgtatcttc atttaattca tccattgaaa tattccaatc ataggcaaca
     5461 tcagaacgga acacatatct tgataagacc tcagcagata caactatata cgtttgcata
     5521 ttaaggtctt caaaccccgt atatttcttt gaaccttgtc ctttcttacg gacgttattt
     5581 aggtagtagt gcatcttgtc cgtattaagc cacatctcgt taaatttctt tgtttgaagg
     5641 ggttgtgtct catatcgttc taaaaactcc aaacaacgcc tatacagcca ctccagctta
     5701 tgatagtagg ttccaactcc aattcctaaa atatcacaag tacgactgac tgaaaccctt
     5761 ccaacaacca tcttagcgaa cattggaaga atggtgttct tttgttggtg ataagtagtg
     5821 gtttcttctc tttttggtag aacattagtg aacttcttac acgccttaca ttgatagcgt
     5881 tgagatttgc ccctactttt cccccttttg taaaattgct tcggctcatt gaatggggtt
     5941 gattcttctt ccgagcagcc ttctttatga aattgataat ctggctcaac atcttggatg
     6001 ctattgattt ctataaggcg tttaatttct tcaacaacag accaattaga taaaggggtt
     6061 actgtacagt tttgcgatac acctctgcca ataggattgt cattgcagta cataccttta
     6121 tgacctttat ctttggaact accagtcatt ttatatcgac ttggtttccc ttttacatct
     6181 ttgaatttgt gctgttcttt cccaaaatta caacaaaacg gattgatgca gtaattatat
     6241 tgaatgggat attcagaacc gttccattta aaagacgttg gcaagaacaa cattttgtta
     6301 taccttgttg caaatcgttt tggagttaat aaatcatatt gtttagccct atcttttaat
     6361 tcttcgtttg aaatcggaat tttaacatct acaatttcat cttccttcgt ggctaatctt
     6421 ttaagcttgg tcattgtcta tcaacccact ctatctttga tacccatttt ttcaacaatc
     6481 cgcttattac ttcgcttgtt ggcaatccat tcaataaact tcttatcgtc taaaatgttc
     6541 aataagaatt catccactgc ttcgctttca gtacgctctg catattcagc gtattgctta
     6601 actatcaccc ttacttgctc tgatatttcc caatccacag acttagcgtt cttatttttt
     6661 ggctcaagaa attgcatagg aaaatgcacc cctttttgct tagtaaattg taaccatttt
     6721 aacacaccaa tttgcattcc tacaataatt atttcacgtt cgcattttta tatacatttt
     6781 aacttacatt ttgtggtgta aattaacaac aaacgttgat ttaacaataa aaaacgagta
     6841 tcaaattcag ttgcaatttg atactcattt aggtttacat tttcactttt tgtactccaa
     6901 aactgaacta cttaaa
//
LOCUS       DACGEU010000274         6076 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.guided.126, whole genome shotgun sequence.
ACCESSION   DACGEU010000274 DACGEU010000000
VERSION     DACGEU010000274.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6076)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6076)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6076
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.guided.126"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            256..822
                     /gene="amaP"
                     /locus_tag="IXR40_003010"
     CDS             256..822
                     /gene="amaP"
                     /locus_tag="IXR40_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HAQ4362768.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
     gene            835..1023
                     /locus_tag="IXR40_003011"
     CDS             835..1023
                     /locus_tag="IXR40_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HAQ4362769.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            1036..1593
                     /locus_tag="IXR40_003012"
     CDS             1036..1593
                     /locus_tag="IXR40_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAQ4362770.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            1625..1867
                     /locus_tag="IXR40_003013"
     CDS             1625..1867
                     /locus_tag="IXR40_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAQ4362771.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
     gene            2208..3599
                     /gene="amt"
                     /locus_tag="IXR40_003014"
     CDS             2208..3599
                     /gene="amt"
                     /locus_tag="IXR40_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HAQ4362772.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGFLAMTISMVVSLYEYPTFATSGFSLVFFLLLGGLLWFIPVALCAAEMATV
                     KGWEKGVSQTKRY"
     gene            3994..4467
                     /gene="dfrF"
                     /locus_tag="IXR40_003015"
     CDS             3994..4467
                     /gene="dfrF"
                     /locus_tag="IXR40_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrF"
                     /protein_id="HAQ4362773.1"
                     /translation="MIGLIVARSKNNVIGKNGNIPWKIKGEQKQFRELTTGNVVIMGR
                     KSYEEIGHPLPNRMNIVVSTTTEYQGDNLVSVKSLEDALLLAKGRDVYISGGYGLFKE
                     ALQIVDKMYITEVDLNIEDGDTFFPEFDINDFEVLIGETLGEEVKYTRTFYVRKK"
     gene            4594..5250
                     /locus_tag="IXR40_003016"
     CDS             4594..5250
                     /locus_tag="IXR40_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005603505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HAQ4362774.1"
                     /translation="MNKEWSELNKTMQAQIKKKDTYKRGIDTLLTLRSQLIQTLVSFK
                     EELCREDFNSIPFINADGYHSKTIAYSIWHIFRIEDIVVHTVINEDEQVFFAGNYQER
                     INSPIITTGNELMKQQIADFSKQLNLEELYLYIFEVWESTEKMLERLSYDELKRKIPK
                     ERKGYLESLNVVNDNEKAIWLIDYWCNKDICGLIQMPFSRHWIMHTEACLRIKNKIHS
                     "
     gene            5432..5962
                     /locus_tag="IXR40_003017"
     CDS             5432..5962
                     /locus_tag="IXR40_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAQ4362775.1"
                     /translation="MRKVVLFIAMSLDGYIADGNGGVAWLNGHGNDNENIDTYTEFTK
                     DIDTVLMGWNTSHQVVTELSPQEWVYNKFTTYVLTHKECNSSQQIHFTSENPVLLLER
                     LKQEAGKDIWICGGANLVQQLVSKNMIDKYYISVIPTLLGNGVRLLGNIDREIKLRLC
                     KTQTYNGITDLIYMRR"
BASE COUNT         2071 a          893 c         1282 g         1830 t
ORIGIN      
        1 aataataact gagcataatc tttgcaattt ttaatcttga ataatatcct ttaagtatag
       61 ccagcaatca aaagtaaata gagaataagt aagcaattgt tatttcagta tcagactggc
      121 aataaaacgc cgttatgatc cagcaatgtt tggtagcgct ttatttactg atgctatgct
      181 aactgttcgc tatctatact gtgattgtcg gtagagttat ttacagggta aaaataagtt
      241 tataggaggt ggaaaatgaa taaggggtta aaaataatcg gtgttatcat gagtttactg
      301 ctactttcag tatttctagc gattgcgttg atcaatgcgc cgtatattat gcctgaacaa
      361 ttggaacgat ttcgcttctt tactttaacg aattactaca tgcaacaata tattttctgg
      421 gcagctgtag tatttgccgt tcttgctatt atcatcttgc tagtcgttct tttctatcca
      481 aagtcaagag gaactttcgt tatgaaacgg gaagatggca aactaacaat cgacaaaaaa
      541 gcgatcgaag ggttggtacg ttcccattta cacgaagaag agttcattca ttcacctaaa
      601 gtacggatac gttcaacgaa aaatcgaatc catatccatg tcaacggaga cttgaaacga
      661 acttcttcat tagtagggaa aacaggtgta ttgatgcaag atatcgaaga agaagtaact
      721 aaagtactcg gaacaaaaga aacggtcaaa gtggcagtca catacagcgg ttatgaagaa
      781 caagaagata caagagacta caagcactct cgagtggaat aggagggcca aataatgaaa
      841 gaactatttt cagcatacaa gctccctatt atctttgggg gtcttggact actgctagct
      901 gttttatggt taacgattgg atttttcaag acattgttga tcataatcat gacagcaatt
      961 ggcgcaggaa tcggttttta tttgaaacag tcaggaatag ttgatcaatt ttttaaatca
     1021 taggaggaaa caaagatgga aaacaaaaac atgaatacaa caaatggatc agttttggca
     1081 aatgaaaaag gagaaaaccg catgatgaat ggtgaattga cttatgaaga caaagtcatc
     1141 caaaaaatca tcggttatgc attgaaagat gtagatggtc tattgacatt agatggcgga
     1201 tttttctcaa atatggctga aaaattagtc aacacagata acgtaacagc aggtatcaat
     1261 acagaagtag gtaagaaaca agtagctgtg gatctagatg tgatcgtaga atacggtaaa
     1321 gacatcgaag atatttacaa ccaaatcaaa gaattgatca gtactgaagt aaacaatatg
     1381 acacatttag atgttatcga agtgaatgtg aatgttgcag acatcaaaac acaagaagaa
     1441 taccaaaaag atcaagaaac agtacaagac aaagtaacag aagcagcaaa atccacagga
     1501 caatttgctt cacgccaaac agataaagca aaatctgctg taggcaaagg tgcacaaaaa
     1561 gtcaaagaaa ataacgaacc acgtgtacaa taagaagtaa gaagtcagtt aggaggaatt
     1621 taaaatggga tttatttggg cattaatcgt cggcggtatc attggagcaa ttgcaggagc
     1681 aatcacgaat aaaggatcat caatggggat catcgcaaac atcattgctg gtttagtagg
     1741 ttcagcaatt ggacaagctt tactaggaac ttggggacca acaattgcag gaatggctat
     1801 cattccatca ttgatcggtg caatcatttt agtattagtc gtttcattct ttgcacgtaa
     1861 attataagca aattgaagaa aaacttatgt tgaaatgaag aacaaatttg agaaccgtag
     1921 cgacactcgc tgcggttctt ttttatatat tttatatgaa gtattcttta ttccttatga
     1981 aaaaatatct ttaaaaataa aaaaagacga aaataaacgg ttttctataa aaagaagacc
     2041 gtttattttt tgtctttatt tgtgtgaaaa acgaaaaaga gcacaacaca tcaagctttt
     2101 attaattgtc tgtcttttat aaatgcaagt attaattcaa aaaaacagaa gaaaaaaaca
     2161 actacacctt cttttatact cgtaatcgta gaaaggaggc gaaaaaaatg aatacattac
     2221 ctatcaatac aggagataca gcattcatga ttttatgtac agcaatggtt tgcctgatga
     2281 ctcctggtct agcttttttt tacggcggat tagcacggaa gaataatata ctaacgatca
     2341 tgtctcaatc ttttctctcc gttgggataa caacgattat gtgggtattt ggtggattcg
     2401 gattggcctt tggacgggat atcggcggtg ttattggaaa cccggcagat ttctttttga
     2461 tgagacatgt tacaagcttc cccaacatgt ttcatggtgc aacgattcca tttttaatgt
     2521 tctttcttta ccaactgatg tttatcgtga ttaccgttcc tttgatgaca ggagcttttg
     2581 cagggagatt gaatttaaaa ggctatatta tacttgttat tttttggaat ctgctgattt
     2641 atttccctgt ttgccactgg atatggggtg gcggattttt ggatcagatg ggatttagag
     2701 atttcgctgg tggagcagtc atccacacga cagctggatt cggctcttta gcatgtatcc
     2761 tcacacttgg tcaaagaaag attcctttag gagaaagaag tcagcatagc agtcttatgg
     2821 cagctgctat cggtacagga ctgctttggt ttggctggtt cggttttaat tccggtggtg
     2881 cacttcgagc agatgaacaa gcagtcaatg catttggttc aacattcatc gctcttgcat
     2941 ttgcgatgat tacttggctg atcattgcaa aagtaaaagg aaatggcttt gattttgtcg
     3001 acgtactaac aggatccgtt gctggattgg cagccattac gccttgtgcc ggttatgtag
     3061 aagcaaaaag tgccatgctg attgggatca ttgcgggtat cgtctgtcat gctgctgttg
     3121 attttcgtaa aaagaaacaa tgggatgatg cacttgatgt gtggggtgtt catggcatgg
     3181 gcggattcac aggtacgatt ctgataggga tctttgcatc taacagccat ttactaacga
     3241 atccaagcag ctggtacttc ttagggattc aagtgattgg tgtcatcatt actgccgtgt
     3301 atgcctatgt gctgacaaca gtgattttaa aatcggcgat gcactttaca acgatcacta
     3361 ctacaaaaga agaacaagaa gaaggattgg actttttctt ctttggcttt ttggctatga
     3421 ccatctcaat ggtcgtttca ttatatgaat atcccacatt cgcgacctca ggcttcagct
     3481 tagtattttt cttgttatta ggcggtttgc tatggtttat ccctgtggca ttgtgcgcag
     3541 cagagatggc aacggtgaaa ggatgggaaa aaggtgtttc ccaaacaaaa agatattaag
     3601 aaacagccca tgtttacctg cttgcaaaca aaagaatatt gctactagac taagagatac
     3661 tacataagtg tgttggtatc tcttttttgt tgccgtgaaa cagcagacta tttcatttct
     3721 gcttgattac cttaaaactt attagtctat ggtttgtcaa gggcttgttg cgtgagaaat
     3781 gctgaatatc accctttaca aaacataggc tgataagtaa cttttcaaaa gcagaaaaga
     3841 aatggcaatg cttataacaa tatgatataa tgcagatgaa gacaaaaaag gaatttgtcg
     3901 agctggttag ttcgagataa ttttgagttt gttaagatgt ggtgcacttg atggaatcac
     3961 aggtacgaca tcatattatg gaggatgaaa tagatgatag gtttgattgt tgcgaggtca
     4021 aagaataatg ttataggcaa gaatggtaat ataccatgga aaataaaggg agaacaaaag
     4081 caatttagag agttaacaac gggtaatgtg gttattatgg ggcgaaagtc ttatgaagaa
     4141 atcggtcatc cgttgcctaa tagaatgaat attgttgttt ccaccacaac agagtatcaa
     4201 ggagataatt tagtttcagt taaatcatta gaagatgcat tattattggc taaaggacga
     4261 gatgtataca tatctggtgg atatggacta tttaaggaag ctttgcaaat agtagataaa
     4321 atgtatatca cagaagtaga tttaaatatt gaagatggag atacattctt tccagaattt
     4381 gatatcaatg attttgaagt tttgataggg gaaacacttg gtgaggaagt gaaatatacg
     4441 agaacatttt atgtaaggaa aaaatgaatt gagtaaattt tggatttagg gtgttttcat
     4501 aaatatattg ctttttatgc atatataaat tgttgtaaga caaattccag tttgtatggg
     4561 gcgataaaat cagaatttga gagaggattg aatatgaata aggaatggtc tgaacttaat
     4621 aaaacaatgc aggcacaaat aaaaaagaaa gatacttata agaggggtat tgatacttta
     4681 cttactttac gaagtcagtt aatacaaacc ttagtatctt tcaaagaaga attatgcaga
     4741 gaagatttta actcaatccc cttcataaac gctgatggtt atcatagtaa gacgattgct
     4801 tattctattt ggcatatttt ccgcattgaa gatatagttg tgcatacagt gataaatgaa
     4861 gatgaacaag tattttttgc aggcaattat caagagcgta tcaattcacc tatcattaca
     4921 acaggaaatg aactcatgaa acagcagatt gcagactttt caaaacagct taatctggaa
     4981 gaattatatt tatatatttt cgaagtatgg gaaagcactg agaaaatgct tgaacggtta
     5041 tcttatgatg aattgaaaag aaaaataccg aaagaaagaa aaggatactt agaatcgttg
     5101 aatgtagtaa acgacaatga aaaagcaatt tggctgattg attattggtg taataaagat
     5161 atttgtggac taattcaaat gccgttttca agacattgga ttatgcacac agaagcctgt
     5221 ttgcgtataa agaacaagat acattcatag gcaaaaattt cagtttgtag aactaaggaa
     5281 attggaattt aaggaggaat aaagtatggt tagtgatttt ataagagcag catttccatg
     5341 gattttaatg ggtttatttg tagcaatcag ttgttccctt atgagtaaaa aagagaaata
     5401 aattcctgtt tgtatttata aaagagaaaa aatgagaaaa gtagttttat ttattgccat
     5461 gagccttgac ggatatattg cggacggtaa tggtggagta gcttggctaa atggtcatgg
     5521 aaatgacaat gaaaacatcg acacttatac agaatttacc aaagatatag atactgtctt
     5581 aatggggtgg aatacttctc atcaggttgt tactgaactt tctccgcaag aatgggtata
     5641 taataaattt acaacttatg tattaacaca taaagagtgc aattcttccc aacaaattca
     5701 ttttacaagt gaaaatcctg ttttattatt ggaacggcta aaacaagaag caggaaagga
     5761 tatttggatt tgtggcggag caaatcttgt tcagcagttg gtaagcaaaa atatgattga
     5821 taaatattac atttctgtta ttcctactct gttaggaaat ggggttcgtc ttttgggcaa
     5881 catagacagg gaaataaagt taaggctttg taaaacacag acttataacg gaataaccga
     5941 tttgatttat atgcgtagat aactagagag aaacagaaaa gctgttaaac cgacggagcg
     6001 atccgaccac gttggcggga aaatccttaa gatttttcgg ctctttgtca aatgatgttg
     6061 gtaaagagaa atctta
//
LOCUS       DACGEU010000275         3372 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.guided.157, whole genome shotgun sequence.
ACCESSION   DACGEU010000275 DACGEU010000000
VERSION     DACGEU010000275.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3372)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3372)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3372
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.guided.157"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            162..473
                     /locus_tag="IXR40_003018"
                     /pseudo
     CDS             162..473
                     /locus_tag="IXR40_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017722130.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
     gene            580..972
                     /locus_tag="IXR40_003019"
     CDS             580..972
                     /locus_tag="IXR40_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAQ4362776.1"
                     /translation="MEEVLIDDNMVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCY
                     TLLRPDGKTMFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRA
                     CHVYEKLGGKNDYKDEIVYVYDYEKGDK"
     gene            973..2412
                     /locus_tag="IXR40_003020"
                     /note="aph(2'')-Ia"
     CDS             973..2412
                     /locus_tag="IXR40_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="HAQ4362777.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYGGRDKKYTLE
                     SLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFI
                     GEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLP
                     EHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYL
                     VNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKE
                     IKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYIL
                     LRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGII
                     DFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPI
                     ETIVYGIKNIKQEFIENGRKEIYKRTYKD"
     gene            2594..3241
                     /locus_tag="IXR40_003021"
     CDS             2594..3241
                     /locus_tag="IXR40_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000143686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type A-8 chloramphenicol O-acetyltransferase"
                     /protein_id="HAQ4362778.1"
                     /translation="MTFNIINLETWDRKEYFNHYFNQQTTYSVTKEFDITLLKSMIKN
                     KGYELYPALIYTIVNIINQNKVFRTGINSEGNLGYWEKLNPLYTVFNKETEKFSNIWT
                     ESNVSFNSFYNSYKSDLLEYKDKNEMFPKKPIPENTVPISMIPWIDFSSFNLNIGNNS
                     RFLLPIITIGKFYSKNNKIYLPVSLQVHHAVCDGYHVSLFMSEFQNIVDSVNEWI"
BASE COUNT         1378 a          282 c          551 g         1161 t
ORIGIN      
        1 cttatttgat agtagattta aaactttgca acagaaccgt ctagtgtgtt atactttaca
       61 tggaagttgt accgaaatat tgtgttgtga agtctatata attttaaaat tatgaagtct
      121 atatacgtgc gtaaagatat ttaaagagat taaaaataat aaaaataaaa attgaattaa
      181 aaagagatat ggttgattat tggaacgatt gttttaatga tttacatata ttacaaccag
      241 attggaaaac tatcgaacgt acttctgata gagcaatggt ttttatgttg ttgaatgatg
      301 aagaagaatg gggaaaatta gaaagacgta ctaagaataa atataaaaaa ttaattaaag
      361 aaatatctct aattgattta actgatttaa tgaaatcgac tttaaaagcg aacgaaaaac
      421 aattgcaaaa gcagattgat ttttggcaac gtgaatttag attttggaag taaagtaact
      481 ttgttttata caaaatgtta ctttagtata gtcaagtcca taatcctgtg taaaatacta
      541 tacaatgttt tacacaggag tctggacttg actgagttta tggaagaagt tttaattgat
      601 gataatatgg tttttgatat tgataattta aaaggatttc ttaatgatac cagttcattt
      661 gggtttatag ctaaagaaaa taataaaatt ataggatttg catattgcta tacactttta
      721 agacctgatg gaaaaacaat gttttattta cactcaatag gaatgttacc taactatcaa
      781 gacaaaggtt atggttcaaa attattatct tttattaagg aatattctaa agagattggt
      841 tgttctgaaa tgtttttaat aactgataaa ggtaatccta gagcttgcca tgtatatgaa
      901 aaattaggtg gtaaaaatga ttataaagat gaaatagtat atgtatatga ttatgaaaaa
      961 ggtgataaat aaatgaatat agttgaaaat gaaatatgta taagaacttt aatagatgat
     1021 gattttcctt tgatgttaaa atggttaact gatgaaagag tattagaatt ttatggtggt
     1081 agagataaaa aatatacatt agaatcatta aaaaaacatt atacagagcc ttgggaagat
     1141 gaagttttta gagtaattat tgaatataac aatgttccta ttggatatgg acaaatatat
     1201 aaaatgtatg atgagttata tactgattat cattatccaa aaactgatga gatagtctat
     1261 ggtatggatc aatttatagg agagccaaat tattggagta aaggaattgg tacaagatat
     1321 attaaattga tttttgaatt tttgaaaaaa gaaagaaatg ctaatgcagt tattttagac
     1381 cctcataaaa ataatccaag agcaataagg gcataccaaa aatctggttt tagaattatt
     1441 gaagatttgc cagaacatga attacacgag ggcaaaaaag aagattgtta tttaatggaa
     1501 tatagatatg atgataatgc cacaaatgtt aaggcaatga aatatttaat tgagcattac
     1561 tttgataatt tcaaagtaga tagtattgaa ataatcggta gtggttatga tagtgtggca
     1621 tatttagtta ataatgaata catttttaaa acaaaattta gtactaataa gaaaaaaggt
     1681 tatgcaaaag aaaaagcaat atataatttt ttaaatacaa atttagaaac taatgtaaaa
     1741 attcctaata ttgaatattc gtatattagt gatgaattat ctatactagg ttataaagaa
     1801 attaaaggaa cttttttaac accagaaatt tattctacta tgtcagaaga agaacaaaat
     1861 ttgttaaaac gagatattgc cagtttttta agacaaatgc acggtttaga ttatacagat
     1921 attagtgaat gtactattga taataaacaa aatgtattag aagagtatat attgttgcgt
     1981 gaaactattt ataatgattt aactgatata gaaaaagatt atatagaaag ttttatggaa
     2041 agactaaatg caacaacagt ttttgagggt aaaaagtgtt tatgccataa tgattttagt
     2101 tgtaatcatc tattgttaga tggcaataat agattaactg gaataattga ttttggagat
     2161 tctggaatta tagatgaata ttgtgatttt atatacttac ttgaagatag tgaagaagaa
     2221 ataggaacaa attttggaga agatatatta agaatgtatg gaaatataga tattgagaaa
     2281 gcaaaagaat atcaagatat agttgaagaa tattatccta ttgaaactat tgtttatgga
     2341 attaaaaata ttaaacagga atttatcgaa aatggtagaa aagaaattta taaaaggact
     2401 tataaagatt gattatataa tatatgaaaa gctattataa aagacattag tattaaatag
     2461 tttaaaaaaa tgaaaaataa taaaggcttt agtataatta acgtttaaga ggtgacacaa
     2521 tatatgaaaa aatcagagga ttattcctcc taaatacaaa gagataagat gaaatttagg
     2581 aggaaaatta tatatgactt ttaatattat taatttggaa acttgggata gaaaagaata
     2641 ttttaatcat tatttcaatc aacaaacaac ttacagtgtt actaaagaat ttgatatcac
     2701 tttacttaaa agtatgataa aaaataaagg atatgaactg tatcctgctt tgatttatac
     2761 aattgtaaat attataaatc aaaataaagt atttagaaca ggaattaata gtgagggaaa
     2821 tttgggttat tgggaaaaat taaacccttt atatacagtc tttaataaag aaactgaaaa
     2881 attttctaac atttggacag aatcaaatgt tagttttaat tctttttata atagttataa
     2941 gagtgactta cttgaatata aagataaaaa tgaaatgttt cctaaaaaac caatacctga
     3001 aaacacagtt cctatttcga tgattccttg gattgatttt agttcattta atttaaatat
     3061 tggtaataat agtagattcc tattgccaat tattacaata ggtaaatttt atagtaagaa
     3121 taataagatc tatttaccag tctcattgca agttcatcat gcggtatgtg atggttacca
     3181 tgtttcatta tttatgagtg aatttcaaaa tatagttgat agtgtaaatg aatggattta
     3241 aatctaaaat aactttcata aacttaagta attatgatat ttataagttt atagcaacca
     3301 cattttttgg ttgcttgtgg ttttgatttt gaaggttctg ttgcaaagtt ttaaataaag
     3361 aataaaatcc ct
//
LOCUS       DACGEU010000276         2336 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.guided.178, whole genome shotgun sequence.
ACCESSION   DACGEU010000276 DACGEU010000000
VERSION     DACGEU010000276.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2336)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2336)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2336
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.guided.178"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            316..1365
                     /gene="cfr"
                     /locus_tag="IXR40_003022"
     CDS             316..1365
                     /gene="cfr"
                     /locus_tag="IXR40_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cfr family 23S rRNA
                     (adenine(2503)-C(8))-methyltransferase"
                     /protein_id="HAQ4362779.1"
                     /translation="MQQKNKYIRIQEFLKQNKFPNYRMKQITNAIFPGRINNFNEITV
                     LPKSLRDMLIEEFGESILNIVPLKAQQSTQVSKVLFGISGDEKIETVNMKYKAGWESF
                     CISSQCGCNFGCKFCATGDIGLKRNLTSDEITDQILYFHLQGHSIDSISFMGMGEALA
                     NVQVFDALNVLTDPALFALSPRRLSISTIGIIPNIKKLTQNYPQVNLTFSLHSPFNEQ
                     RSELMPINERYPLSDVMDTLDEHIRVTSKKVYIAYIMLHGVNDSIEHAKEVVNLLRGR
                     YRSGNLYHVNIIRYNPTVSSRMRFEEANEKCLVNFYKELKSAGIKVTIRSQFGIDIDA
                     ACGQLYGNYQKTNSQ"
     gene            2066..2336
                     /locus_tag="IXR40_003023"
                     /pseudo
     CDS             2066..2336
                     /locus_tag="IXR40_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008728838.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
BASE COUNT          850 a          310 c          427 g          749 t
ORIGIN      
        1 cggtaaacgg tgcaggttag tttaactaca tttatatcca aaattgtttg tttttcaaat
       61 tacatgtatt tttttgagtt tacataggga aagatttatg gtatactatt taacacttat
      121 attgacaaga aagaggtgaa agcaatgtta actgttttta gaattttgtt tggtaaaaat
      181 gcaaaagttg gtaatcgttc ggcatacaaa gggagtagtc tgtccttttt taagccatat
      241 aaccatacaa aaacagttat cggagctttt cctctacggc aaacaaacca gagttatatg
      301 gaaggatgag aaaacatgca acaaaaaaat aagtatataa gaattcaaga gttcttgaag
      361 cagaataaat ttcctaatta tagaatgaaa caaattacaa atgctatatt cccagggaga
      421 ataaataatt tcaacgaaat aacggttctt cctaaatcac taagagatat gttaattgag
      481 gagtttggag aatcgatttt aaatattgtt cctttaaaag cacaacaatc tacacaagtt
      541 tcaaaagtct tatttggaat ttcaggagac gaaaaaatag aaacggtaaa tatgaaatat
      601 aaagctggtt gggagtcatt ttgtatatca tcgcagtgcg gttgtaattt tggttgtaaa
      661 ttttgtgcaa ctggagatat aggtttaaaa cgtaacttaa cttcagatga aattactgac
      721 cagattttgt actttcactt acaagggcat tcaattgaca gtatttcttt tatgggaatg
      781 ggagaagcat tagcgaatgt acaagttttt gatgctttaa atgtacttac agatcctgcg
      841 ttgtttgctt taagtccgcg taggttatct atatccacta taggaattat tccaaacatt
      901 aaaaaattga ctcaaaacta tccgcaggtc aacctgacat tttcattaca ttctcctttt
      961 aatgaacagc gaagtgagtt aatgccaatt aatgaacgct acccattatc agatgtgatg
     1021 gatacattag atgagcatat acgagtaacc tcaaaaaaag tttatattgc ttatattatg
     1081 ttgcacggag ttaatgattc tattgaacat gcgaaagaag tcgtaaacct tttaagaggt
     1141 agatatagga gtgggaactt gtatcatgtg aacatcatta gatataaccc gactgttagt
     1201 tcacggatgc ggtttgaaga agcaaatgag aaatgtcttg tcaactttta taaagaatta
     1261 aagtcagcag gaattaaagt taccattaga agtcaatttg gcattgatat agacgctgct
     1321 tgcggtcaat tgtatggaaa ctatcaaaaa accaatagcc agtaacttga ggtgagagtg
     1381 atgtttagaa cgtgggaagt accctaataa tttatttagt aacgataaat aaacttatta
     1441 ggatatttat gataaaagga atcttagaaa gaaaaatagg catcactcaa gtggagctaa
     1501 aaagtcgttt gtaaaaattg aaactgcaat taaattattg aatgtgaaaa atggtgatga
     1561 ttagtgttaa acaaaaaaat aatttcagtc aaagtatcag tagagatcat gtagtcatta
     1621 cggatttttg gacgttgact gacaataatg aaattcaact accgtccaac atggaaatta
     1681 tatgcaataa ttatttgaag agtttgaaat tgatgtatca gaagattact ctaaacagta
     1741 gttggaaaaa tttgtcatgc gagaattgcg gatgcagtga attattgata atcaggtgga
     1801 agacagtagt gtatccaatg aagagatgaa cacgaatacc aaaaatcact taaaataagg
     1861 tggatatgca aaaggaatac aatcgtgtta tccttgatat gaaaagcaag aaaagaaatg
     1921 ggaaacattt gttctcaatt taaaaaggca acgtcaattg aaatatttat aatttcgctt
     1981 atctaaaagg ccttagagca tattttaatg aacaaaattg aaaggactga acctataata
     2041 atgattcact aatccataaa ctattttgta tttatacttt acagccattt taagaagttt
     2101 tggcaatact atgtttcaag cagttgcaat gcttgtgtct actttattga atgctatttt
     2161 agatcctatt ttcattaaca taattggatt tcacggagcg gcaatcgcaa ccttaatatc
     2221 acagattatt tgtttggcgt ttatgtgcat ttatatttat cgtaaaaaat tatttaacct
     2281 ttcactatct gattttgata caaaagagat tatgccgttt gtaaaaaatg ctgtgc
//
LOCUS       DACGEU010000277          921 bp    DNA     linear   BCT 13-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW10882
            SAMN05375115-rid9571823.guided.225, whole genome shotgun sequence.
ACCESSION   DACGEU010000277 DACGEU010000000
VERSION     DACGEU010000277.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05375115
            Sequence Read Archive: SRR3870887
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 921)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 921)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-MAR-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-MAR-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000703459.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000703459.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 03/06/2020 20:43:07
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,024
            CDSs (total)                      :: 2,959
            Genes (coding)                    :: 2,898
            CDSs (with protein)               :: 2,898
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 61
            CDSs (without protein)            :: 61
            Pseudo Genes (ambiguous residues) :: 0 of 61
            Pseudo Genes (frameshifted)       :: 29 of 61
            Pseudo Genes (incomplete)         :: 30 of 61
            Pseudo Genes (internal stop)      :: 10 of 61
            Pseudo Genes (multiple problems)  :: 8 of 61
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..921
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05375115-rid9571823.guided.225"
                     /isolate="UW10882"
                     /isolation_source="abdominal drainage"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Heidelberg"
                     /collection_date="2013"
                     /collected_by="Robert Koch Institut"
     gene            308..856
                     /gene="aac(6')"
                     /locus_tag="IXR40_003024"
     CDS             308..856
                     /gene="aac(6')"
                     /locus_tag="IXR40_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HAQ4362780.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT          334 a          131 c          187 g          269 t
ORIGIN      
        1 atctaaaaat tctaaaaatt aagattatta tatgaaaaca ggttttattt gtcaattcat
       61 aattggtttt ttttaaagca aaagataatc tatatcatga tgaacaaaca gagttttttc
      121 ctccaattga tggctttcct gatctttcct attttgaata aagtgtttct gtataatttt
      181 ttattttata agtaagataa ataatgaaag aatagagata ctgattggta gctaaagatt
      241 tttgagcgag aacatttcgt tttttcaaaa ggactgttag aataagcaag aacaaggggg
      301 aagacgtatg ataatcagtg aatttgaccg taataatcca gtattgaaag atcagctttc
      361 tgatttactg agactgactt ggccggaaga atatggagac agctcggcag aagaagtaga
      421 agaaatgatg aatccagaac gaatcgcggt agcagcggta gaccaagatg agttagtagg
      481 atttattggt gcaatccctc aatacggtat cacaggttgg gaattgcatc cattagttgt
      541 agaaagctcc cgacgaaaga accaaatagg tactcgatta gtcaattact tagaaaaaga
      601 agtagcttcc agaggaggaa tcacgattta tttaggtacg gatgatttag accatggaac
      661 aacgttaagt caaacggacc tgtatgagca tacatttgat aaagtggctt ccatccagaa
      721 ccttcgtgaa catccgtatg aattctatga aaaattaggt tataaaatcg taggtgtctt
      781 accaaatgca aatggctggg acaaaccgga tatttggatg gcaaaaacga ttattcctcg
      841 accaaattct caataataaa aagaggttgt gacagaagta atcagcttca agaaataaga
      901 aggaatttac gaaaattact t
//
